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[1][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 325 bits (834), Expect = 1e-87
Identities = 151/188 (80%), Positives = 169/188 (89%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRPRA+ KKL+EEWA PLKSVEDIYE+F+++CLGKL+++PWSELDGLQPETKII
Sbjct: 376 LSDYQFMRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKII 435
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L KIN KGFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+
Sbjct: 436 NEQLGKINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVD 495
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K K PF+TY+AVNK G W SNV TDVNAVTWGVFP KEIIQPT+VDP SFSVWKDEAF
Sbjct: 496 KCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAF 555
Query: 546 XIWSRAWA 569
IWSR WA
Sbjct: 556 EIWSRGWA 563
[2][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 320 bits (821), Expect = 4e-86
Identities = 148/182 (81%), Positives = 165/182 (90%)
Frame = +3
Query: 24 MRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEK 203
MRPRA+ KKL+EEWA PLKSVEDIYE+F+++CLGKL+++PWSELDGLQPETKIIN+ L K
Sbjct: 1 MRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGK 60
Query: 204 INTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP 383
IN KGFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAYLEFFCSK+KL+ALV+K K P
Sbjct: 61 INLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFP 120
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
F+TY+AVNK G W SNV TDVNAVTWGVFP KEIIQPT+VDP SFSVWKDEAF IWSR
Sbjct: 121 FVTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRG 180
Query: 564 WA 569
WA
Sbjct: 181 WA 182
[3][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 319 bits (817), Expect = 1e-85
Identities = 149/188 (79%), Positives = 167/188 (88%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRPRA+ KKL EEWA PLKSVEDIYE+F+++CLGKL+++PWSEL+GLQPETKII
Sbjct: 379 LSDYQFMRPRARGKKLFEEWASPLKSVEDIYEKFKVYCLGKLKSSPWSELEGLQPETKII 438
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L +IN KGFLTINSQPAVN EKSDSP+VGWGGPGGYVYQKAYLEFFCSKEKL+ALVE
Sbjct: 439 NEQLGRINLKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVE 498
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
+ K P +TYMAVN+ G W SNV TDVNAVTWGVFPAKEIIQPT+VDP SFSVWKDEAF
Sbjct: 499 RCKAFPLVTYMAVNRGGSWISNVALTDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDEAF 558
Query: 546 XIWSRAWA 569
IWSR WA
Sbjct: 559 EIWSRGWA 566
[4][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 313 bits (803), Expect = 4e-84
Identities = 147/188 (78%), Positives = 165/188 (87%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRPRA+DKKL +EW VPLKS+ED+ ERF FCLGKL+++PWSELDGLQPE+KII
Sbjct: 365 LTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKII 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L IN+KGFLTINSQPAVNGEKSDS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+
Sbjct: 425 NELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVD 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K K P LTYMAVNKEG W SNVG +VNAVTWGVFPA+EIIQPT+VDP SF VWKDEAF
Sbjct: 485 KCKGHPSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAF 544
Query: 546 XIWSRAWA 569
IWSR WA
Sbjct: 545 EIWSRGWA 552
[5][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 310 bits (795), Expect = 4e-83
Identities = 146/188 (77%), Positives = 164/188 (87%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRPRA+DKKL +EW VPLKS+ED+ ERF FCLGKL+++PWSELDGLQPE+KII
Sbjct: 365 LTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKII 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L IN+KGFLTINSQPAVNGEKSDS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+
Sbjct: 425 NELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVD 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K K LTYMAVNKEG W SNVG +VNAVTWGVFPA+EIIQPT+VDP SF VWKDEAF
Sbjct: 485 KCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAF 544
Query: 546 XIWSRAWA 569
IWSR WA
Sbjct: 545 EIWSRGWA 552
[6][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 310 bits (795), Expect = 4e-83
Identities = 146/188 (77%), Positives = 164/188 (87%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRPRA+DKKL +EW VPLKS+ED+ ERF FCLGKL+++PWSELDGLQPE+KII
Sbjct: 358 LTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESKII 417
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L IN+KGFLTINSQPAVNGEKSDS +VGWGGPGGYVYQKAYLEFFCS+EKL+ALV+
Sbjct: 418 NELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVD 477
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K K LTYMAVNKEG W SNVG +VNAVTWGVFPA+EIIQPT+VDP SF VWKDEAF
Sbjct: 478 KCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAF 537
Query: 546 XIWSRAWA 569
IWSR WA
Sbjct: 538 EIWSRGWA 545
[7][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 309 bits (792), Expect = 8e-83
Identities = 144/184 (78%), Positives = 160/184 (86%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QFMRPRA+DKKL +EW VPL S EDI+E+F+ CLGKL+T+PWSELDGLQPETKIIN+ L
Sbjct: 384 QFMRPRARDKKLHDEWVVPLSSAEDIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQL 443
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
KIN KGFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAY+EFFCS +KL AL+EK K
Sbjct: 444 GKINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKA 503
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LTYMAVN+ G SNVGQ DVNAVTWGVFP K+IIQPT+VDP SFSVWKDEAF IW+
Sbjct: 504 LPQLTYMAVNRGGTLLSNVGQNDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWT 563
Query: 558 RAWA 569
R WA
Sbjct: 564 RGWA 567
[8][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 304 bits (778), Expect = 4e-81
Identities = 142/184 (77%), Positives = 159/184 (86%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF RPRA+DKKL +EW VPLKSVEDI E+F+ CLG L+++PWSELDGLQPET+IIN+ L
Sbjct: 369 QFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQL 428
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
K+N+KGFLTINSQP+VN E+SDSPTVGWGGP GYVYQKAYLEFFCSKEKLDA+VEK K
Sbjct: 429 IKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA 488
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P +TYMAVNK W SN Q DVNAVTWGVFPAKEIIQPTIVDP SF+VWKDEAF WS
Sbjct: 489 LPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWS 548
Query: 558 RAWA 569
R+WA
Sbjct: 549 RSWA 552
[9][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 302 bits (774), Expect = 1e-80
Identities = 137/188 (72%), Positives = 160/188 (85%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF RP+ +DKKL +EW VPLKS+ED+ E+F+ C+G L+++PWSELDGLQPETKII
Sbjct: 175 LSDYQFARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKII 234
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L KIN+ GFLTINSQP+VN KSDSP +GWGGPGGYVYQKAYLEFFCSK+KLD LVE
Sbjct: 235 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 294
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K+K P +TYMAVNK W SN G++DVNAVTWGVFPAKE+IQPTIVDP SF VWKDEAF
Sbjct: 295 KSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAF 354
Query: 546 XIWSRAWA 569
IWSR+WA
Sbjct: 355 EIWSRSWA 362
[10][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 302 bits (774), Expect = 1e-80
Identities = 137/188 (72%), Positives = 160/188 (85%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF RP+ +DKKL +EW VPLKS+ED+ E+F+ C+G L+++PWSELDGLQPETKII
Sbjct: 365 LSDYQFARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKII 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ L KIN+ GFLTINSQP+VN KSDSP +GWGGPGGYVYQKAYLEFFCSK+KLD LVE
Sbjct: 425 NEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVE 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K+K P +TYMAVNK W SN G++DVNAVTWGVFPAKE+IQPTIVDP SF VWKDEAF
Sbjct: 485 KSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAF 544
Query: 546 XIWSRAWA 569
IWSR+WA
Sbjct: 545 EIWSRSWA 552
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 300 bits (769), Expect = 4e-80
Identities = 144/184 (78%), Positives = 155/184 (84%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF RPR + KKL EEWAVPLKSVEDI ERF FC GKL ++PWSELDGLQPETKII+D L
Sbjct: 369 QFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQL 428
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
KIN KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K
Sbjct: 429 VKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKA 488
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LTY+AVNK+G SN+ VNAVTWGVFP KEIIQPT+VDP SF VWKDEAF IW+
Sbjct: 489 FPSLTYIAVNKDGESFSNIAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWT 548
Query: 558 RAWA 569
R WA
Sbjct: 549 RGWA 552
[12][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 294 bits (752), Expect = 4e-78
Identities = 141/183 (77%), Positives = 152/183 (83%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF RPR + KKL EEWAVPLKSVEDI ERF FC GKL ++PWSELDGLQPETKII+D L
Sbjct: 369 QFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQL 428
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
IN KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFC+KEKLD L+EK K
Sbjct: 429 VNINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKA 488
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LTY+AVNK+G SN+ VNAVTWGVFP KEIIQPT+VD SF VWKDEAF IW+
Sbjct: 489 FPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWT 548
Query: 558 RAW 566
R W
Sbjct: 549 RGW 551
[13][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 292 bits (747), Expect = 1e-77
Identities = 140/188 (74%), Positives = 156/188 (82%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF RPR + KKL EEWAVP+KSVEDI ERF FC GKL ++PWSELDGLQPETKII
Sbjct: 365 LTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKII 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
+D L KIN KGFLTINSQPAVNGE+SDS +VGWGGPGGYVYQKAYLEFFCSKEKLD L+E
Sbjct: 425 DDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIE 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K+K P LTY+AVNK+G SN+ VNAVTWGVFP KEI+QPT+VD SF VWKDEAF
Sbjct: 485 KSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAF 544
Query: 546 XIWSRAWA 569
IWS+ WA
Sbjct: 545 EIWSKGWA 552
[14][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 292 bits (747), Expect = 1e-77
Identities = 140/188 (74%), Positives = 156/188 (82%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF RPR + KKL EEWAVP+KSVEDI ERF FC GKL ++PWSELDGLQPETKII
Sbjct: 8 LTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKII 67
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
+D L KIN KGFLTINSQPAVNGE+SDS +VGWGGPGGYVYQKAYLEFFCSKEKLD L+E
Sbjct: 68 DDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIE 127
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K+K P LTY+AVNK+G SN+ VNAVTWGVFP KEI+QPT+VD SF VWKDEAF
Sbjct: 128 KSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAF 187
Query: 546 XIWSRAWA 569
IWS+ WA
Sbjct: 188 EIWSKGWA 195
[15][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 292 bits (747), Expect = 1e-77
Identities = 140/188 (74%), Positives = 156/188 (82%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF RPR + KKL EEWAVP+KSVEDI ERF FC GKL ++PWSELDGLQPETKII
Sbjct: 365 LTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKII 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
+D L KIN KGFLTINSQPAVNGE+SDS +VGWGGPGGYVYQKAYLEFFCSKEKLD L+E
Sbjct: 425 DDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIE 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K+K P LTY+AVNK+G SN+ VNAVTWGVFP KEI+QPT+VD SF VWKDEAF
Sbjct: 485 KSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAF 544
Query: 546 XIWSRAWA 569
IWS+ WA
Sbjct: 545 EIWSKGWA 552
[16][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 291 bits (746), Expect = 2e-77
Identities = 132/188 (70%), Positives = 159/188 (84%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QF+R R++ KK++EEW VPL S+ DI E+F FC+GKL++NPWSELDGLQPET I
Sbjct: 365 LNDYQFLRRRSRSKKILEEWVVPLSSIVDIQEKFANFCVGKLKSNPWSELDGLQPETVKI 424
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE 365
N+ LE++N KGFLTINSQPAVNGEKSDSP++GWGG GYVYQKAY+EFFCS EKL+ LVE
Sbjct: 425 NEKLEQLNRKGFLTINSQPAVNGEKSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVE 484
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
K K+ PF+TY+AVNK+G +N+G TDVNAVTWGVFPAKE+IQPT+VDPVSF VWKDEAF
Sbjct: 485 KAKNLPFVTYIAVNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAF 544
Query: 546 XIWSRAWA 569
W + WA
Sbjct: 545 QAWEQEWA 552
[17][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 288 bits (736), Expect = 3e-76
Identities = 138/184 (75%), Positives = 154/184 (83%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF RPR + KKL EEWAVPLKSV+DI ERF FC GKL+++PWSELDGLQPET II+D L
Sbjct: 357 QFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQL 416
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
KIN+KGFLTINSQPAVN EKS+SP+VGWGGPGGYVYQKAY+EFFC+KEKL L+EK+K
Sbjct: 417 VKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKA 476
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LTY+AVNKEG SN+ VNAVTWGVFP KEIIQPT+VD SF VWKDEAF IWS
Sbjct: 477 FPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWS 536
Query: 558 RAWA 569
R WA
Sbjct: 537 RGWA 540
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 274 bits (700), Expect = 4e-72
Identities = 126/184 (68%), Positives = 148/184 (80%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF+R + + KKL +EWAVPL S ED+ + F +C G L T+PWSEL+GLQPET IND L
Sbjct: 369 QFLRKKTRSKKLQKEWAVPLNSCEDVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKL 428
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
+NT+GFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K
Sbjct: 429 VALNTQGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKS 488
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LT++AVN +G +SN+G VNAVTWGVFPAKE+IQPT+VDPVSF VWKDEAF W
Sbjct: 489 NPSLTFIAVNAKGETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQTWD 548
Query: 558 RAWA 569
WA
Sbjct: 549 HEWA 552
[19][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 271 bits (694), Expect = 2e-71
Identities = 128/184 (69%), Positives = 146/184 (79%)
Frame = +3
Query: 18 QFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHL 197
QF R + + KKL +EWAVPL S ED+ F +C G L T+PWSEL+GLQPET IN+ L
Sbjct: 369 QFTRKKTRSKKLQKEWAVPLNSSEDVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKL 428
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
+N GFLTINSQPAVNGEKSDSP+VGWGGPGGYVYQKAY+EFFCS EKL A++EK K
Sbjct: 429 VALNQGGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKT 488
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
P LTY+AVN +G KSNVG T VNAVTWGVFPAKE+IQPT+VDPVSF VWKDEAF W
Sbjct: 489 SPSLTYIAVNAKGETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWD 548
Query: 558 RAWA 569
+ WA
Sbjct: 549 QEWA 552
[20][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 180 bits (456), Expect = 8e-44
Identities = 90/195 (46%), Positives = 121/195 (62%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG-------KLRTNPWSELDGLQ 167
Y + +++ ++ + L++ W L S E +YE F + G K+ PW++ D L
Sbjct: 403 YYLFYLKSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLA 461
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ D LEK+N +G LTINSQP +NG+ S VGWG GGYV+QKAYLEFF S E
Sbjct: 462 PETNLLKDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSEN 521
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K P + Y VN +G +N NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 522 VTALLQVLKKYEPRVNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFM 581
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 582 YWKDEAFALWIEQWA 596
[21][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 179 bits (454), Expect = 1e-43
Identities = 92/194 (47%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGK-------LRTNPWSELDGLQ 167
Y + +++P AK ++L++ W L ++D+ + F + GK +R PW++ D L
Sbjct: 392 YYLFYLKPNAKKEELLDMWGHELTCLQDVCDVFTNYITGKESKNGKKVRKIPWND-DDLA 450
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET IND L +IN++G LTINSQP VN S P VGWG PGGYV+QKAYLEFF S+E
Sbjct: 451 AETSFINDKLARINSRGVLTINSQPNVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSREN 510
Query: 348 LDALVEKTKDRPFLTYMAVNKEGVWK-SNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL + P + Y + EG +N Q AVTWGVFP KEIIQPT+VDPVSF
Sbjct: 511 VQALFKVLPKYPNVNYHIIKFEGDDDYTNCDQQQPIAVTWGVFPGKEIIQPTVVDPVSFK 570
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W+ W
Sbjct: 571 FWKDEAFTLWTEYW 584
[22][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 179 bits (454), Expect = 1e-43
Identities = 94/195 (48%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG-------KLRTNPWSELDGLQ 167
Y++ +++ +K +L++ W L+SVED+YE F F G K+ PWS D L
Sbjct: 387 YHIFYLKNTSKKDELLKMWGEKLESVEDVYEIFTCFVSGERNKYGYKVDALPWSN-DALA 445
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET I LE IN+KG LTINSQP VN S GWGGP GYVYQKAYLEFF S E+
Sbjct: 446 LETLFIKKSLEYINSKGILTINSQPNVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAER 505
Query: 348 LDALVEKTKDRPFLTYMAVN-KEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
L+E + P + Y A++ E + SN AVTWGVFP +EI+QPT+VDP SFS
Sbjct: 506 FKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIAVTWGVFPGREILQPTVVDPTSFS 565
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W+ WA
Sbjct: 566 YWKDEAFALWTNQWA 580
[23][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 177 bits (449), Expect = 5e-43
Identities = 86/195 (44%), Positives = 120/195 (61%), Gaps = 9/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSEL--------DGL 164
+++ +++ + +++ ++ W L +ED+Y F+ + GK N W D L
Sbjct: 381 HHLFYLKSKESEEERLKMWGEKLDCIEDVYHVFQCYLSGK--KNKWGYKVKSLPLNDDEL 438
Query: 165 QPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE 344
QPET +++D L +IN GFLT NSQPAVN S GWGG GGY+YQKAYLEFF K+
Sbjct: 439 QPETSLLSDQLYRINGHGFLTTNSQPAVNAALSTDERFGWGGAGGYIYQKAYLEFFMHKK 498
Query: 345 KLDALVEKTKDRPFLTYMAVNKEGVW-KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSF 521
+D L+E D P + Y ++ G + K+N + AVTWGVFP KEIIQPT+VDP+SF
Sbjct: 499 NVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVTWGVFPGKEIIQPTVVDPISF 558
Query: 522 SVWKDEAFXIWSRAW 566
+ WKDEAF +W W
Sbjct: 559 NFWKDEAFSLWIEKW 573
[24][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 176 bits (447), Expect = 8e-43
Identities = 88/195 (45%), Positives = 121/195 (62%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ N PW++ D L
Sbjct: 397 YYLFYLKSKSPREELLKMWGQELNSEESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLA 455
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ + L+K+N +G LTINSQP VNG+ S P VGWG GYV+QKAYLEFF S E
Sbjct: 456 PETNLLKNELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEM 515
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K P + Y VN G +N NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 516 VSALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPNAVTWGIFPGREIIQPTVVDPVSFV 575
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 576 YWKDEAFALWIEQWA 590
[25][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 176 bits (446), Expect = 1e-42
Identities = 91/179 (50%), Positives = 117/179 (65%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R +++ E W P ++D+ F+ FC G+++ PWSE + ET +I+D L K+N
Sbjct: 383 RYSNEEAKEMWGAPT-CLDDVKTLFQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQ 440
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
GFLTINSQPAV+G +SD GWG GYVYQKAYLEFF S E LDAL+ + + P +T
Sbjct: 441 LGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQIT 500
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AVN +G ++N NAVTWGVFP EIIQPTIV+ +SF WKDEA+ I R WA
Sbjct: 501 YHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWA 558
[26][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 175 bits (444), Expect = 2e-42
Identities = 91/188 (48%), Positives = 112/188 (59%), Gaps = 5/188 (2%)
Frame = +3
Query: 18 QFMRPR----AKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDG-LQPETKI 182
QFMR A+ +K W SV+D+ + F + G++ PW+ELDG L E
Sbjct: 365 QFMRRHSTGEARREKARAAWGAAPASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAA 424
Query: 183 INDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALV 362
I + L +N G+LTINSQP VNG SD GWGGPGGYVY KAY+EFFCS E L
Sbjct: 425 IREPLAALNANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLR 484
Query: 363 EKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEA 542
K P +TY+A G N+ VNAVTWGVFP KE+IQPT+V SF+VWKDEA
Sbjct: 485 AKLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEA 544
Query: 543 FXIWSRAW 566
F +W+ W
Sbjct: 545 FELWTSEW 552
[27][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 174 bits (441), Expect = 4e-42
Identities = 87/195 (44%), Positives = 120/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ N PW++ D L
Sbjct: 397 YYLFYLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLA 455
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ L+K+N +G LTINSQP VNG+ S P VGWG GYV+QKAYLEFF S E
Sbjct: 456 PETNLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEM 515
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K P + Y VN G +N +AVTWG+FP +EIIQPT+VDPVSF
Sbjct: 516 VTALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFM 575
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 576 YWKDEAFALWIEQWA 590
[28][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 174 bits (440), Expect = 5e-42
Identities = 86/195 (44%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F + + + PW++ + L
Sbjct: 407 YYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLA 465
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ D LEK+N +G LTINSQP +NG+ S P VGWG GGYVYQKAYLEFF S E
Sbjct: 466 PETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSEN 525
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K P + Y VN G +N NAVTWG+F +EI+QPT+VDPVSF
Sbjct: 526 VTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFM 585
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 586 SWKDEAFALWIEQWA 600
[29][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 174 bits (440), Expect = 5e-42
Identities = 86/195 (44%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F + + + PW++ + L
Sbjct: 407 YYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLA 465
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ D LEK+N +G LTINSQP +NG+ S P VGWG GGYVYQKAYLEFF S E
Sbjct: 466 PETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSEN 525
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K P + Y VN G +N NAVTWG+F +EI+QPT+VDPVSF
Sbjct: 526 VTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFM 585
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 586 SWKDEAFALWIEQWA 600
[30][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 173 bits (438), Expect = 9e-42
Identities = 87/195 (44%), Positives = 120/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L E ++E F + G+ N PW++ D L
Sbjct: 405 YYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLA 463
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ D LEK+N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S E
Sbjct: 464 TETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEI 523
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K + Y VN +G +N NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 524 VTALLKVLKKYELRVNYHIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFL 583
Query: 525 VWKDEAFXIWSRAWA 569
WKDEAF +W WA
Sbjct: 584 SWKDEAFALWIEQWA 598
[31][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 172 bits (435), Expect = 2e-41
Identities = 82/195 (42%), Positives = 124/195 (63%), Gaps = 8/195 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
+++ ++R +AK +++++ W L V+D++E F+ + G+ N PW++ + L
Sbjct: 348 HHLFYLRSKAKKEQMLKMWGQQLNDVQDVFEVFKCYISGEKNENGVKVTSLPWND-EELA 406
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET I + L N+ G L+INSQP+VN S P +GWGG GGY+YQKAYLEFF S E
Sbjct: 407 LETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEV 466
Query: 348 LDALVEKTKDRPFLTYMAVNK-EGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ L+++ K+ P + Y VN + V +N AVTWGVFP +EI+QPT+VDP+SF
Sbjct: 467 VYILLQELKNYPQVNYHVVNNHDTVDITNCDSQTPVAVTWGVFPGREIVQPTVVDPISFK 526
Query: 525 VWKDEAFXIWSRAWA 569
+WKDEAF +W + W+
Sbjct: 527 IWKDEAFSLWEQQWS 541
[32][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform 3
n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 170 bits (431), Expect = 6e-41
Identities = 84/194 (43%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 426 YYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 484
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 485 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 544
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 545 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 604
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 605 FWKDEAFALWIERW 618
[33][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform 4
n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 170 bits (431), Expect = 6e-41
Identities = 84/194 (43%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 444 YYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 502
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 503 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 562
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 563 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 622
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 623 FWKDEAFALWIERW 636
[34][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 170 bits (431), Expect = 6e-41
Identities = 84/194 (43%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 403 YYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 461
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 462 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 521
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 522 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 581
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 582 FWKDEAFALWIERW 595
[35][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 170 bits (430), Expect = 8e-41
Identities = 86/179 (48%), Positives = 114/179 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R ++ ++ W P +++D+ F FC G+L PWS+ L ET +IN+ L +N
Sbjct: 292 RQTKEEALDLWGSPT-TIQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNE 349
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GF TINSQPAV+G +SD P GWG GYVYQKAYLEFF S ++LD L+ + P +T
Sbjct: 350 RGFFTINSQPAVDGARSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQIT 409
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AVN +G ++N NAVTWG FP EI+QPTIV+ +SF WKDEA+ I R WA
Sbjct: 410 YHAVNAQGDMRTNTTSDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWA 467
[36][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 169 bits (428), Expect = 1e-40
Identities = 88/166 (53%), Positives = 107/166 (64%), Gaps = 3/166 (1%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQP---ETKIINDHLEKINTKGFLTIN 233
W P S D++ F FC G L PWS QP ET +I + L K+N G+LTIN
Sbjct: 381 WGHPTTS-SDLHALFARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTIN 435
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKE 413
SQPAV+G +SD GWG PGGYVYQKAYLEFF S + L L+ + + P +TY AVNK+
Sbjct: 436 SQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQ 495
Query: 414 GVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
G ++N NAVTWGVFP KEI+QPTIV+ VSF WKDEAF +
Sbjct: 496 GDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL 541
[37][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 169 bits (427), Expect = 2e-40
Identities = 83/194 (42%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 426 YYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 484
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 485 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 544
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 545 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 604
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 605 FWKDEAFALWIEQW 618
[38][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 169 bits (427), Expect = 2e-40
Identities = 83/194 (42%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 444 YYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 502
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 503 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 562
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 563 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 622
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 623 FWKDEAFALWIEQW 636
[39][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 169 bits (427), Expect = 2e-40
Identities = 83/194 (42%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F L+ G+ N PW++ + L
Sbjct: 403 YYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 461
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 462 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 521
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 522 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 581
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 582 FWKDEAFALWIEQW 595
[40][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 168 bits (426), Expect = 2e-40
Identities = 90/196 (45%), Positives = 116/196 (59%), Gaps = 9/196 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y++ F+R R KL W L S D+++ F+ F G + N PW++ DGL
Sbjct: 376 YHLFFLRSRTAKDKLRSLWGKELTSEADVWKVFKHFITGAVNENGVKVTETPWND-DGLS 434
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET +++ L + N G LTINSQP VN S P GWG GGY+ QKAYLEFF +K
Sbjct: 435 PETNVLSSTLSRYNELGVLTINSQPNVNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHY 494
Query: 348 LDAL-VEKTKDRPFLTYMAVNKEGVW-KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSF 521
+AL K P + Y +NK G +N +++ NAVTWG+F KEIIQPT+VDPVSF
Sbjct: 495 AEALKTVLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVTWGIFAGKEIIQPTVVDPVSF 554
Query: 522 SVWKDEAFXIWSRAWA 569
VWKDEAF +W WA
Sbjct: 555 IVWKDEAFGLWHERWA 570
[41][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 167 bits (422), Expect = 7e-40
Identities = 84/194 (43%), Positives = 119/194 (61%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + ++ ++ ++L++ W L S E ++E F + G+ N PW++ + L
Sbjct: 400 YYLFCLKSKSPREELLKMWGQELTSEESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLA 458
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L+K+N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S E
Sbjct: 459 AETSLLKEELQKVNRRGILTINSQPNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSET 518
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K + Y VN +G +N NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 519 VAALLKVLKKYELRVNYHIVNVKGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFM 578
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 579 SWKDEAFALWIEQW 592
[42][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 166 bits (421), Expect = 9e-40
Identities = 81/194 (41%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ N PW++ + L
Sbjct: 402 YYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLA 460
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 461 AETSLMKEELLRVNRQGVLTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 520
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 521 VEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 580
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 581 FWKDEAFALWIEQW 594
[43][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 166 bits (421), Expect = 9e-40
Identities = 84/194 (43%), Positives = 118/194 (60%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + ++ + +L++ W L S E ++E F + G+ N PW++ + L
Sbjct: 397 YYLFCLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLA 455
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L K+N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S E
Sbjct: 456 AETSLMKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSET 515
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 516 VEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 575
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 576 FWKDEAFALWIEQW 589
[44][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 166 bits (421), Expect = 9e-40
Identities = 88/197 (44%), Positives = 117/197 (59%), Gaps = 8/197 (4%)
Frame = +3
Query: 3 LLYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDG 161
L Y + PR ++L++ W L E ++E F + G+ N PW++ D
Sbjct: 395 LFYLKSSLPPR---EELLKMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DP 450
Query: 162 LQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSK 341
L ET ++ + LEK+N +G LTINSQP +NG+ S P GWG GGYV+QKAYLEFF S
Sbjct: 451 LATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSN 510
Query: 342 EKLDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVS 518
E + AL++ K + Y VN +G +N NAVTWG+FP +EIIQPT+VDPVS
Sbjct: 511 EIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVS 570
Query: 519 FSVWKDEAFXIWSRAWA 569
F WKDEAF +W WA
Sbjct: 571 FLSWKDEAFALWIEQWA 587
[45][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 166 bits (420), Expect = 1e-39
Identities = 81/194 (41%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E +++ F + G+ N PW++ + L
Sbjct: 402 YYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLA 460
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 461 AETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 520
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 521 VEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 580
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 581 FWKDEAFALWIEQW 594
[46][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 166 bits (419), Expect = 1e-39
Identities = 84/183 (45%), Positives = 112/183 (61%), Gaps = 8/183 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQPETKIINDHLEK 203
++L++ W L E ++E F + G+ N PW++ D L ET ++ + LEK
Sbjct: 274 EELLKMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEK 332
Query: 204 INTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP 383
+N +G LTINSQP +NG+ S P GWG GGYV+QKAYLEFF S E + AL++ K
Sbjct: 333 VNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYE 392
Query: 384 F-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSR 560
+ Y VN +G +N NAVTWG+FP +EIIQPT+VDPVSF WKDEAF +W
Sbjct: 393 LRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIE 452
Query: 561 AWA 569
WA
Sbjct: 453 QWA 455
[47][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 165 bits (418), Expect = 2e-39
Identities = 87/179 (48%), Positives = 114/179 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W PL S++D+ + F + GKL + PWSE T I ND ++ +N
Sbjct: 366 KGTNEQNIKLWGTPL-SIKDLSDLFVRYMEGKLESLPWSEQPITGEATSIRNDLID-LNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAVNG KS PT GWG GYVYQKAYLE S E + ++ + + P T
Sbjct: 424 RGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AVNK+G K+N NAVTWGVFP KEI+QPTIV+ VSF WKDE + + + WA
Sbjct: 484 YYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWA 541
[48][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 165 bits (417), Expect = 3e-39
Identities = 82/194 (42%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG-------KLRTNPWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G K+ PW++ + L
Sbjct: 528 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLA 586
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 587 AETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 646
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 647 VGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 706
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 707 FWKDEAFALWIEQW 720
[49][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 165 bits (417), Expect = 3e-39
Identities = 82/194 (42%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLG-------KLRTNPWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G K+ PW++ + L
Sbjct: 444 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLA 502
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 503 AETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 562
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+ AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 563 VGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 622
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 623 FWKDEAFALWIEQW 636
[50][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 164 bits (416), Expect = 3e-39
Identities = 81/194 (41%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E +++ F G+ N PW++ + L
Sbjct: 402 YYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLA 460
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 461 AETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 520
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 521 VEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 580
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 581 FWKDEAFALWIEQW 594
[51][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 164 bits (415), Expect = 4e-39
Identities = 82/164 (50%), Positives = 106/164 (64%)
Frame = +3
Query: 78 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVNGE 257
+S +D+Y F +C G ++ PW++ L E++ I + L +N GFLTINSQPA+NG
Sbjct: 398 QSEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFLTINSQPAINGL 456
Query: 258 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 437
S GWGG G VY+KAY+EFF S E L+E K P +TY AVN++G K+N
Sbjct: 457 PSTDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGDSKTNTK 516
Query: 438 QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
T NAVTWG+FP KEIIQPT+VD SF VWKDEAF +W W+
Sbjct: 517 GT--NAVTWGIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWS 558
[52][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 163 bits (413), Expect = 7e-39
Identities = 79/194 (40%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 408 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 466
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 467 AETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 526
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EI+QPT+VDP+SF
Sbjct: 527 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFM 586
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 587 FWKDEAFALWIEQW 600
[53][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 163 bits (413), Expect = 7e-39
Identities = 79/194 (40%), Positives = 121/194 (62%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 443 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 501
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 502 AETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 561
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EI+QPT+VDP+SF
Sbjct: 562 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFM 621
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 622 FWKDEAFALWIEQW 635
[54][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 163 bits (412), Expect = 1e-38
Identities = 84/173 (48%), Positives = 111/173 (64%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KSV+D+ + F F GKL PWSE + E+ II D L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSVKDLSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA+NG KS P GWG GYVYQKAYLE S +D ++ + + P LT
Sbjct: 424 RGFLTINSQPAINGAKSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y +NK G ++N T NAVTWG+F +KE+IQPTIV+ VSF WKDEA+ +
Sbjct: 484 YHCINKNGELRTNSSDTP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL 535
[55][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 161 bits (408), Expect = 3e-38
Identities = 79/194 (40%), Positives = 120/194 (61%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 443 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 501
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +N + S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 502 AETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 561
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 562 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 621
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 622 FWKDEAFALWIEQW 635
[56][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 161 bits (408), Expect = 3e-38
Identities = 79/194 (40%), Positives = 120/194 (61%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 443 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 501
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +N + S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 502 AETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 561
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 562 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 621
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 622 FWKDEAFALWIEQW 635
[57][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 161 bits (408), Expect = 3e-38
Identities = 79/194 (40%), Positives = 120/194 (61%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 402 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 460
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +N + S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 461 AETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 520
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 521 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 580
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF +W W
Sbjct: 581 FWKDEAFALWIEQW 594
[58][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 161 bits (407), Expect = 4e-38
Identities = 82/165 (49%), Positives = 105/165 (63%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
++W P K+++DI E F + K+ + PWSE L E I D L ++N +G LTINS
Sbjct: 374 KKWGEP-KAIQDIAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKRGLLTINS 431
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 416
QPAVNG KS P GWG GYVYQK+YLE D ++ + ++ P LTY AV K+G
Sbjct: 432 QPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDG 491
Query: 417 VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
+SNV NAVTWGVFP KEI+QPTIV+ +SF WKDEAF +
Sbjct: 492 ELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL 536
[59][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 160 bits (406), Expect = 5e-38
Identities = 87/186 (46%), Positives = 114/186 (61%)
Frame = +3
Query: 12 NVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIIND 191
N +R + +++ I+ W P KS++D+ + F + GK+ PWS+ + PET I +
Sbjct: 360 NAYGVRLKGTNEQNIKLWGAP-KSIKDLSDIFVRYLNGKVERLPWSD-SAVTPETSDIQN 417
Query: 192 HLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKT 371
L +N +GFLTINSQPAVNG KS P GWG GYVYQKAYLE E +D L+ +
Sbjct: 418 ELLDLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRI 477
Query: 372 KDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
+ P LTY VNK G K+ NAVTWG+F +KEIIQPTIV+ VSF WKDEA+ +
Sbjct: 478 EKNPDLTYYCVNKTGELKAR-SDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL 536
Query: 552 WSRAWA 569
WA
Sbjct: 537 -GEDWA 541
[60][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 160 bits (404), Expect = 8e-38
Identities = 83/179 (46%), Positives = 110/179 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ ++ W P+ + D+ + F + GKL + PWSE + E I L +N
Sbjct: 366 KGTNEQNVKLWGSPM-CIRDLSDLFVRYMEGKLDSLPWSE-QAITTEAGPIRSDLIDLNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAVNG KS P GWG GYVYQKAYLE F S E + ++ + + P T
Sbjct: 424 RGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AVNK+G K+N NAVTWGVFP KEI+QPTIV+ VSF WKDE + + + WA
Sbjct: 484 YYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQQWA 541
[61][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 160 bits (404), Expect = 8e-38
Identities = 86/175 (49%), Positives = 105/175 (60%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
K ++ W P S DI F FC KL PWS+ Q ET +I + L +N GFL
Sbjct: 371 KDALKLWGHPT-SFADIASLFSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFL 428
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAV 404
TINSQPAVN +SD P GWG GYVYQKAYLEFF + L+ L+ + +TY +
Sbjct: 429 TINSQPAVNSARSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVI 488
Query: 405 NKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
NK G ++N NAVTWGVFP KEI+QPTIV+ VSF WKDEAF + + WA
Sbjct: 489 NKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWA 542
[62][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 159 bits (403), Expect = 1e-37
Identities = 79/194 (40%), Positives = 119/194 (61%), Gaps = 8/194 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ + PW++ + L
Sbjct: 443 YYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLA 501
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N G LTINSQP +N + S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 502 AETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET 561
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
++AL++ K + Y V+ +G +N + NAVTWG+FP +EIIQPT+VDP+SF
Sbjct: 562 VEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFM 621
Query: 525 VWKDEAFXIWSRAW 566
WKDEAF W W
Sbjct: 622 FWKDEAFAPWIEQW 635
[63][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 159 bits (401), Expect = 2e-37
Identities = 82/173 (47%), Positives = 108/173 (62%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++DI E F + + + PWSE + E II L ++N
Sbjct: 366 KGSNEQNIKLWGQP-KSIKDIAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAV+G KS P GWG GYVYQKAYLE + + + LV + + P LT
Sbjct: 424 RGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y AV K G ++N NAVTWGVFP KEI+QPTIV+ +SF WKDEAF +
Sbjct: 484 YYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL 536
[64][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 158 bits (400), Expect = 2e-37
Identities = 83/171 (48%), Positives = 104/171 (60%), Gaps = 3/171 (1%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P ++E++ F FC G+L PWS+ ET II L K+N GFLTINSQP
Sbjct: 337 WGYPT-TLEEVSVLFAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQP 394
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVNG +SD GWG GYVYQKAYLEFF L L++ + +TY +NK G
Sbjct: 395 AVNGARSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDL 454
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRAW 566
++N NAVTWGVFP KEIIQPTIV+ +SF WKDEA+ + W+R +
Sbjct: 455 QTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQWARLY 505
[65][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 157 bits (397), Expect = 5e-37
Identities = 82/167 (49%), Positives = 101/167 (60%), Gaps = 1/167 (0%)
Frame = +3
Query: 72 PLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVN 251
P KS ED+YE F L+ GK+ PW E LQPE+ +I L +N GFLTINSQP+VN
Sbjct: 419 PTKS-EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVN 476
Query: 252 GEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKS 428
S + GWGGPGGY+YQKAY E FCS E + LV K + AVN G +
Sbjct: 477 AALSTHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQE 536
Query: 429 NVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
V A+TWGVFP +EI+QPTI DP F VW +EAF +W+ W+
Sbjct: 537 GTELGGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWS 583
[66][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 156 bits (395), Expect = 9e-37
Identities = 82/182 (45%), Positives = 107/182 (58%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K++ W P KS +I + F +C K+ + PWS+L + E +I D L +N
Sbjct: 369 RMSPKEITTSWGSP-KSYSEIGDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNR 426
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
FLTINSQPA+NGEKS P GWG P GYV+QK Y+EFF L+ L E K ++
Sbjct: 427 NAFLTINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVS 486
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRA 563
Y NK G +N NAVTWGVFP +EIIQPTIV+ SF WKDEA+ + W+ A
Sbjct: 487 YFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSLGMEWANA 546
Query: 564 WA 569
++
Sbjct: 547 YS 548
[67][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 155 bits (392), Expect = 2e-36
Identities = 81/173 (46%), Positives = 105/173 (60%), Gaps = 3/173 (1%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
++W P ++V+DI F + +L PWSE + E ++I D L +N +G +TINS
Sbjct: 374 KKWGEP-QTVKDIANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIALNNRGLITINS 431
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 416
QPAVNG KS P GWG GYVYQKAYLE S E + + +D P +TY AV K G
Sbjct: 432 QPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSG 491
Query: 417 VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRAW 566
+N NAVTWGVFP KEI+QPTIV+ +SF WKDEAF + W+R +
Sbjct: 492 NLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEWARCY 544
[68][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 155 bits (391), Expect = 3e-36
Identities = 80/184 (43%), Positives = 107/184 (58%), Gaps = 8/184 (4%)
Frame = +3
Query: 39 KDKKLIEEWAVPLKSVEDIYERFRLFCLG-------KLRTNPWSELDGLQPETKIINDHL 197
KD +L+ W L S +D+++ F + G K+ PWS+ + L PET + + L
Sbjct: 387 KDSELLSMWGRELNSEQDVFDIFVCYLTGRDNKQGFKVTELPWSDGE-LAPETIPLVEKL 445
Query: 198 EKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD 377
N G LTINSQP++N S+ P GWG PGGYV+QKAYLEFF +E L + KD
Sbjct: 446 VHANQNGILTINSQPSLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKD 505
Query: 378 RPFLTYMAVNKEGVWK-SNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
+ + VN G +N NAVTWGVFP EI+QPT+VDP++F WKDEAF +W
Sbjct: 506 GTRINFHLVNSSGESDFTNANMYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLW 565
Query: 555 SRAW 566
+ W
Sbjct: 566 KQQW 569
[69][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 155 bits (391), Expect = 3e-36
Identities = 81/173 (46%), Positives = 106/173 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++D+ F F KL PWSE + ET II L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSSIFVRFLEAKLDRLPWSE-SSITEETDIIKQDLIDLNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA+NG S P GWG GYVYQKAYLE E +D ++ + + LT
Sbjct: 424 RGFLTINSQPAINGASSSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A NK G K+N + NAVTWG+F +KE+IQPTIV+ VSF WKDEA+ +
Sbjct: 484 YYATNKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL 535
[70][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 154 bits (389), Expect = 4e-36
Identities = 82/173 (47%), Positives = 106/173 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++D+ F F G L PWSE + ET I L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAVNG S P GWG GYVYQKAYLE E + ++ + + P LT
Sbjct: 424 RGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A+NK G K+N + NAVTWG+F +KE+IQPTIV+ VSF WKDEAF +
Sbjct: 484 YYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL 535
[71][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 154 bits (388), Expect = 6e-36
Identities = 82/173 (47%), Positives = 106/173 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++D+ F F G L PWSE + ET I L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAVNG S P GWG GYVYQKAYLE E + ++ + + P LT
Sbjct: 424 RGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A+NK G K+N + NAVTWG+F +KE+IQPTIV+ VSF WKDEAF +
Sbjct: 484 YYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL 535
[72][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 154 bits (388), Expect = 6e-36
Identities = 83/182 (45%), Positives = 113/182 (62%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F G L PWSE + ET+II L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
KGFLTINSQPA++G S P GWG GYVYQKAYLE S +D ++ + + LT
Sbjct: 424 KGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRA 563
Y VNK+G K+N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ + W++
Sbjct: 484 YYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKC 542
Query: 564 WA 569
A
Sbjct: 543 HA 544
[73][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 154 bits (388), Expect = 6e-36
Identities = 83/182 (45%), Positives = 113/182 (62%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F G L PWSE + ET+II L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
KGFLTINSQPA++G S P GWG GYVYQKAYLE S +D ++ + + LT
Sbjct: 424 KGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRA 563
Y VNK+G K+N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ + W++
Sbjct: 484 YYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKC 542
Query: 564 WA 569
A
Sbjct: 543 HA 544
[74][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 154 bits (388), Expect = 6e-36
Identities = 83/179 (46%), Positives = 111/179 (62%), Gaps = 3/179 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++DI + F F GKL PWS+ + E I + L K+N
Sbjct: 366 KGTNEQNIKLWGEP-KSIKDISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQ 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPAVNG KS P GWG G+VYQKAYLE +D L+ + + LT
Sbjct: 424 RGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSR 560
Y A NK+G K+N + NA+TWG+F +EIIQPTIV+ VSF WKDEA+ + WS+
Sbjct: 484 YHATNKKGELKTNT-RDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWSK 541
[75][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 154 bits (388), Expect = 6e-36
Identities = 82/164 (50%), Positives = 100/164 (60%), Gaps = 3/164 (1%)
Frame = +3
Query: 78 KSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVNGE 257
KSV+DI F + ++ T PWSE L E + I D L +N +G +TINSQPAVNG
Sbjct: 375 KSVKDIATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGV 433
Query: 258 KSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVWKSNVG 437
+S P GWG P GYVYQKAYLE + L E+ D P LTY AV K G +N
Sbjct: 434 RSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNAT 493
Query: 438 QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSR 560
NAVTWGVFP KEI+QPT+V+ +SF WKDEAF + W+R
Sbjct: 494 YEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEWAR 537
[76][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 153 bits (387), Expect = 8e-36
Identities = 81/180 (45%), Positives = 111/180 (61%)
Frame = +3
Query: 12 NVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIIND 191
N +R + +++ I+ W P KS++D+ + F + GKL PWS+ + ET I +
Sbjct: 360 NAYGVRLKGTNEQNIKLWGAP-KSIKDLSDIFLRYLNGKLERLPWSD-SSVTLETSDIQN 417
Query: 192 HLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKT 371
L +N +GFLTINSQPAVNG KS P GWG G+VYQKAYLE E ++ L+ +
Sbjct: 418 ELLDLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRI 477
Query: 372 KDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
+ P LTY +NK G ++ NAVTWG+F +KEIIQPTIV+ VSF WKDEA+ +
Sbjct: 478 EKNPDLTYYCINKTGELRAR-SDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL 536
[77][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 153 bits (386), Expect = 1e-35
Identities = 81/179 (45%), Positives = 114/179 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R +K++E W P K+V+D+ + GKL + PWS++ + E + I + ++N
Sbjct: 366 RQSPQKVLELWGEP-KTVDDLKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LTINSQPAVNG KS P GWG GYVYQKAYLE + E + LV+K +++ +T
Sbjct: 424 RGILTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEIT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
+ AVNK G ++N NAVTWG++P KE+IQPTIV+ +SF WK+EAF + S WA
Sbjct: 484 FYAVNKTGNLQTN-APGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGSE-WA 540
[78][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 152 bits (384), Expect = 2e-35
Identities = 77/183 (42%), Positives = 114/183 (62%), Gaps = 8/183 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S ++E F L+ G+ N PW++ + L
Sbjct: 433 YYLFYLKSKSPKEELLKMWGEELTSEASVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLA 491
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
ET ++ + L ++N +G LTINSQP +NG+ S P VGWG GGYV+QKAYLEFF S+E
Sbjct: 492 AETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRET 551
Query: 348 LDALVEKTKDRPF-LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFS 524
+AL++ K + Y VN +G +N + NAVTWG+FP +EIIQPT+VDPVSF
Sbjct: 552 AEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM 611
Query: 525 VWK 533
WK
Sbjct: 612 FWK 614
[79][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 152 bits (383), Expect = 2e-35
Identities = 76/152 (50%), Positives = 100/152 (65%), Gaps = 5/152 (3%)
Frame = +3
Query: 126 KLRTNPWSELD-GLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY 302
K+ PW+E + G+QPET +I++ L N G LT+NSQP+VNG S P VGWG PGGY
Sbjct: 442 KVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGY 501
Query: 303 VYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVW-KSNVGQTDVNAVTWGV 470
YQKAYLE F + E D L++ +R F + Y A+NK+ + K+N +T AVTWGV
Sbjct: 502 CYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGV 560
Query: 471 FPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
FP EI QPT+VDP+SF W+DEA+ +W W
Sbjct: 561 FPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQW 592
[80][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 152 bits (383), Expect = 2e-35
Identities = 76/152 (50%), Positives = 100/152 (65%), Gaps = 5/152 (3%)
Frame = +3
Query: 126 KLRTNPWSELD-GLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY 302
K+ PW+E + G+QPET +I++ L N G LT+NSQP+VNG S P VGWG PGGY
Sbjct: 463 KVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGY 522
Query: 303 VYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAVNKEGVW-KSNVGQTDVNAVTWGV 470
YQKAYLE F + E D L++ +R F + Y A+NK+ + K+N +T AVTWGV
Sbjct: 523 CYQKAYLECFMTAELSDKLIQ-IIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGV 581
Query: 471 FPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
FP EI QPT+VDP+SF W+DEA+ +W W
Sbjct: 582 FPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQW 613
[81][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 151 bits (381), Expect = 4e-35
Identities = 78/173 (45%), Positives = 105/173 (60%), Gaps = 3/173 (1%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
++W P + DI F + ++ PWSE + E +I D+L +N +G +T+NS
Sbjct: 374 QKWGEPT-CIRDIANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLDLNKRGLITVNS 431
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 416
QPAVNG KS P GWG GYVYQKAYLE S E + ++ ++ P LTY AV K G
Sbjct: 432 QPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSG 491
Query: 417 VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRAW 566
+ ++N NAVTWGVFP KEI+QPTIV+ +SF WKDEAF + W+R +
Sbjct: 492 MLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGSDWARCY 544
[82][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 150 bits (379), Expect = 6e-35
Identities = 76/165 (46%), Positives = 104/165 (63%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
++W P K+V+DI + F + ++ + PWSE L E I D L ++N +G LT+NS
Sbjct: 374 KKWGEP-KTVQDIAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVELNKRGLLTVNS 431
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 416
QPAVNG KS GWG GYVYQK+YLE + + ++ + ++ P LT+ AV K+G
Sbjct: 432 QPAVNGVKSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDG 491
Query: 417 VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
+SN NAVTWGVFP KEI+QPTIV+ +SF WKDEAF +
Sbjct: 492 ELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL 536
[83][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 150 bits (379), Expect = 6e-35
Identities = 79/173 (45%), Positives = 109/173 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F GKL PWSE + ET II L +N+
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S ++ ++ + + LT
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[84][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 150 bits (379), Expect = 6e-35
Identities = 78/173 (45%), Positives = 109/173 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F G L PWSE + ET ++ L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S +D ++ + + P LT
Sbjct: 424 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK+G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 484 YYCVNKKGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 535
[85][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 150 bits (378), Expect = 8e-35
Identities = 79/179 (44%), Positives = 110/179 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ DI + F + GKL PWS+ + E I D+L ++N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LT+NSQPAVNG +S P GWG G+VYQKAYLE F LD L+ + + P LT
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV K ++N + NA+TWG+F +EI+QPTIVD +SF WKDEA+ + WA
Sbjct: 484 YHAVAKNRELRTNT-RDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWA 540
[86][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 150 bits (378), Expect = 8e-35
Identities = 79/173 (45%), Positives = 109/173 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F GKL PWSE + ET II L +N+
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S ++ ++ + + LT
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[87][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 150 bits (378), Expect = 8e-35
Identities = 78/188 (41%), Positives = 113/188 (60%), Gaps = 9/188 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK E W +P +S+ D+ + G L++ PWS+ + +T++I D L +N
Sbjct: 371 RQSPKKAFELWGLP-QSLADLSGIIINYLKGDLKSLPWSD-GPVGDDTRVIVDDLIYLNQ 428
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD----- 377
GF T+NSQPA+N KS GWG GYVYQK YLEFFC K+ + L+++ ++
Sbjct: 429 HGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKG 488
Query: 378 ----RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
F++Y AV+K+G +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 489 AESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVY 548
Query: 546 XIWSRAWA 569
+++ WA
Sbjct: 549 RLFTE-WA 555
[88][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 150 bits (378), Expect = 8e-35
Identities = 79/179 (44%), Positives = 110/179 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ DI + F + GKL PWS+ + E I D+L ++N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LT+NSQPAVNG +S P GWG G+VYQKAYLE F LD L+ + + P LT
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV K ++N + NA+TWG+F +EI+QPTIVD +SF WKDEA+ + WA
Sbjct: 484 YHAVAKNRELRTNT-RDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWA 540
[89][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 149 bits (377), Expect = 1e-34
Identities = 79/173 (45%), Positives = 103/173 (59%), Gaps = 3/173 (1%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
++W P S++DI F + ++ PWSE + E +I D L ++N +G +T+NS
Sbjct: 374 KKWGEPT-SIKDIANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIELNNRGLITVNS 431
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG 416
QPAVNG KS P GWG GYVYQKAYLE S E + + + P LTY AV K G
Sbjct: 432 QPAVNGVKSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSG 491
Query: 417 VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRAW 566
+N NAVTWGVFP KEI+QPTIV+ +SF WKDEAF + W+R +
Sbjct: 492 NLHTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGMEWARCY 544
[90][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 149 bits (377), Expect = 1e-34
Identities = 79/173 (45%), Positives = 109/173 (63%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F GKL PWSE + ET II L +N+
Sbjct: 366 KGTNEQNIQLWGKP-KSLKELSEIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S ++ ++ + + LT
Sbjct: 424 RGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 484 YYCVNKTGELRTNTTDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL 535
[91][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 149 bits (377), Expect = 1e-34
Identities = 79/173 (45%), Positives = 108/173 (62%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F G L PWSE + ET +I L +N
Sbjct: 352 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNR 409
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S +D ++ + + P LT
Sbjct: 410 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 469
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 470 YYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 521
[92][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 149 bits (375), Expect = 2e-34
Identities = 78/188 (41%), Positives = 112/188 (59%), Gaps = 9/188 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK E W +P +S+ ++ + G L++ PWS+ + +TK+I D L +N
Sbjct: 371 RQSPKKAFELWGLP-QSLAELSGIIINYLKGDLKSLPWSD-GPVGDDTKVIVDDLIYLNQ 428
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD----- 377
GF T+NSQPA+N KS GWG GYVYQK YLEFFC K+ + L++ ++
Sbjct: 429 HGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKG 488
Query: 378 ----RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
F++Y AV+K+G +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 489 AESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVY 548
Query: 546 XIWSRAWA 569
+++ WA
Sbjct: 549 RLFTE-WA 555
[93][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 149 bits (375), Expect = 2e-34
Identities = 78/173 (45%), Positives = 108/173 (62%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++++ E F F G L PWSE + ET ++ L +N
Sbjct: 257 KGTNEQNIKLWGEP-KSLKELSEIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNR 314
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GFLTINSQPA++G S P GWG GYVYQKAYLE S +D ++ + + P LT
Sbjct: 315 RGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLT 374
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y VNK G ++N + NAVTWG+F +KEIIQPTIV+ +SF WKDEA+ +
Sbjct: 375 YYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL 426
[94][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 148 bits (374), Expect = 2e-34
Identities = 79/179 (44%), Positives = 108/179 (60%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P S+ D+ E F F G L PWS+ + PET I D L ++N
Sbjct: 366 KGTNEQNIKLWGEP-NSLRDLAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNR 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+GF TINSQPAVNG KS P GWG G+VYQKAYLE +D L+ + + LT
Sbjct: 424 RGFFTINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV K+G ++N + NA+TWG+F +E++QPTIV+ VSF WKDEA+ + WA
Sbjct: 484 YHAVTKKGELRTNT-RDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWA 540
[95][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 148 bits (374), Expect = 2e-34
Identities = 75/169 (44%), Positives = 101/169 (59%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P+ +DI F+ LG+ PW + ++ ETK I D L K+ K + T+ SQP
Sbjct: 419 WGYPVDE-DDITNIFKRHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQP 476
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVN S GWG GG+V+QKA++E F S +AL ++ D P +TY+A N +G +
Sbjct: 477 AVNAAPSSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEF 536
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
K+N NAVTWGVFP +EIIQ TI+ PVSF W+DEA+ IW WA
Sbjct: 537 KTNASLDSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWGE-WA 584
[96][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 148 bits (374), Expect = 2e-34
Identities = 78/179 (43%), Positives = 110/179 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ DI + F + GKL PWS+ + E I ++L ++N
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNG 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LT+NSQPAVNG +S P GWG G+VYQKAYLE F LD L+ + + LT
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV KEG ++N + NA+TWG+F +EI+QPTIV+ +SF WKDEA+ + WA
Sbjct: 484 YHAVAKEGELRTNT-RDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWA 540
[97][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 148 bits (373), Expect = 3e-34
Identities = 77/182 (42%), Positives = 111/182 (60%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS++D+ F + GKL PWS+ + E K I +L ++N
Sbjct: 366 KGTNEQNIQLWGEP-KSIKDLSRLFVRYLEGKLSRLPWSDTP-ISSEAKAIKPNLIELNN 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LTINSQPAVNG KS P GWG G+VYQKAYLE LD L+ + + LT
Sbjct: 424 RGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRA 563
Y AV+K G ++N + NA+TWG+F +E++QPTIV+ +SF WKDEA+ + W++
Sbjct: 484 YHAVSKNGELRTNTHDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWAKC 542
Query: 564 WA 569
A
Sbjct: 543 HA 544
[98][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 148 bits (373), Expect = 3e-34
Identities = 77/179 (43%), Positives = 110/179 (61%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ D+ + F + GKL PWS+ + E I D+L ++N+
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDVTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNS 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G LT+NSQPAVNG +S P GWG G+VYQKAYLE F LD L+ + + P LT
Sbjct: 424 RGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV K ++N + NA+TWG+F +EI+QPTIV+ +SF WKDEA+ + WA
Sbjct: 484 YHAVAKNRELRTNT-RDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWA 540
[99][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 147 bits (370), Expect = 7e-34
Identities = 73/151 (48%), Positives = 100/151 (66%), Gaps = 4/151 (2%)
Frame = +3
Query: 126 KLRTNPWSELD-GLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY 302
K+ PW+E + G+QPET +I++ L N G LT+NSQP+VNG S P VGWG PGGY
Sbjct: 464 KVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGY 523
Query: 303 VYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAVNKEGVW-KSNVGQTDVNAVTWGVF 473
YQKAYLE F + E + L++ ++ P + Y A++K+ + K+N +T AVTWGVF
Sbjct: 524 CYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPIAVTWGVF 583
Query: 474 PAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
P EI QPT+VDP+SF W+DEA+ +W W
Sbjct: 584 PGSEIAQPTVVDPLSFRAWRDEAYQMWMAQW 614
[100][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 146 bits (368), Expect = 1e-33
Identities = 75/184 (40%), Positives = 109/184 (59%), Gaps = 9/184 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK + W P ++++D + + G+L++ PWS+ + +T ++ ++L +N
Sbjct: 371 RQSPKKAYDLWGTP-QTLKDFSDIIVSYLQGELKSLPWSD-GPIGEDTSVMVENLINLNH 428
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALV---------E 365
KGFLT+NSQPA+N KS GWG GYVYQK YLEFFC K+ L L+ E
Sbjct: 429 KGFLTMNSQPALNAVKSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSE 488
Query: 366 KTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
++Y AV+K G +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 489 GDASSSIISYYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVY 548
Query: 546 XIWS 557
+++
Sbjct: 549 RLFT 552
[101][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 145 bits (367), Expect = 2e-33
Identities = 81/184 (44%), Positives = 108/184 (58%), Gaps = 11/184 (5%)
Frame = +3
Query: 33 RAKDKKLIEEWAVP--LKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKI 206
R KK + W P LK DI F GKL + PWS+ + +++II D+L +
Sbjct: 371 RQSPKKAFDLWGHPGTLKQFSDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIAL 426
Query: 207 NTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK------ 368
N KGF T+NSQP++N KS+ GWG GYVYQK YLEFF K+ + AL+ +
Sbjct: 427 NKKGFFTLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNR 486
Query: 369 ---TKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDE 539
+ LTY AV+++G SN D+NAVTWGVFP +EI+QPTIV+ VSF WKDE
Sbjct: 487 GQGDSNSSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDE 546
Query: 540 AFXI 551
+ +
Sbjct: 547 VYRL 550
[102][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 145 bits (367), Expect = 2e-33
Identities = 82/192 (42%), Positives = 108/192 (56%), Gaps = 10/192 (5%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSEL-DGL 164
Y + +++ + + + + L+++ DI + F F + N PW+E DG+
Sbjct: 416 YYLFYLKGQPTRDEQLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGI 475
Query: 165 QPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE 344
+ ET +I D L N+ GFLTINSQP++NG S P VGWG PGGY YQKAYLEFF S+
Sbjct: 476 RAETSLIKDQLLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQA 535
Query: 345 KLDALVEKTKDRPFLTYMAVNKEGV--WKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVS 518
+ L L VN + W +N T AVTWGVFP EI QPT+VDP+S
Sbjct: 536 NAEVLWSLLPSYSRLNCHIVNHDATIDW-TNTETTMPIAVTWGVFPGSEIAQPTVVDPLS 594
Query: 519 FSVWKDEAFXIW 554
F VWKDEAF W
Sbjct: 595 FRVWKDEAFSAW 606
[103][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 145 bits (367), Expect = 2e-33
Identities = 81/184 (44%), Positives = 108/184 (58%), Gaps = 11/184 (5%)
Frame = +3
Query: 33 RAKDKKLIEEWAVP--LKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKI 206
R KK + W P LK DI F GKL + PWS+ + +++II D+L +
Sbjct: 371 RQSPKKAFDLWGHPGTLKQFSDIIISF---LSGKLNSLPWSD-SAIGQDSEIIVDNLIAL 426
Query: 207 NTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK------ 368
N KGF T+NSQP++N KS+ GWG GYVYQK YLEFF K+ + AL+ +
Sbjct: 427 NKKGFFTLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNR 486
Query: 369 ---TKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDE 539
+ LTY AV+++G SN D+NAVTWGVFP +EI+QPTIV+ VSF WKDE
Sbjct: 487 GQGDSNSSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDE 546
Query: 540 AFXI 551
+ +
Sbjct: 547 VYRL 550
[104][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 145 bits (366), Expect = 2e-33
Identities = 75/160 (46%), Positives = 94/160 (58%), Gaps = 1/160 (0%)
Frame = +3
Query: 90 DIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDS 269
D+YE F + G + PW E LQPE+ +I L K+N GFLT+NSQP V+G S
Sbjct: 385 DVYEVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDGLPSCH 443
Query: 270 PTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEG-VWKSNVGQTD 446
GWGG GG VYQKAY E F S K + L + D P L AVN G + V +
Sbjct: 444 KVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGG 503
Query: 447 VNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
V A+TWGVFP +EI+QPTI DP +F +W +EAF +W W
Sbjct: 504 VTALTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMW 543
[105][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 144 bits (364), Expect = 4e-33
Identities = 77/187 (41%), Positives = 111/187 (59%), Gaps = 8/187 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K+ +E W P +S++D+ + F + G L + PWS+ + E ++ D L +N
Sbjct: 364 RHSPKRAVELWGKP-QSIDDVIDLFVRYLQGNLSSLPWSDGE-TSKEINVLLDDLLALNR 421
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP--- 383
+G LTINSQP VNG S+ GWG G+VYQK YLEFF + L L+ ++
Sbjct: 422 QGILTINSQPCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSY 481
Query: 384 -----FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFX 548
LT+ AVN +G +N + D+NAVTWG+FP KE++QPTIV+ SF WKDEAF
Sbjct: 482 SSNFNTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFR 541
Query: 549 IWSRAWA 569
++ +AW+
Sbjct: 542 VF-KAWS 547
[106][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 144 bits (364), Expect = 4e-33
Identities = 78/186 (41%), Positives = 108/186 (58%), Gaps = 11/186 (5%)
Frame = +3
Query: 33 RAKDKKLIEEWAVP--LKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKI 206
R K+ E W P LK + DI + G L++ PWS+ + +TK+I D L ++
Sbjct: 372 RQSPKRAYELWGTPGSLKELSDIVISY---LKGDLKSLPWSD-GSVGDDTKVIVDDLVEL 427
Query: 207 NTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD--- 377
N +G LT+NSQPA+N KS GWG GYVYQK YLEFFC K+ + L++ D
Sbjct: 428 NKRGLLTMNSQPALNSIKSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNN 487
Query: 378 ------RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDE 539
++Y AV+ +G +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE
Sbjct: 488 NQGDASSAIISYYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDE 547
Query: 540 AFXIWS 557
+ ++S
Sbjct: 548 VYRLFS 553
[107][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 144 bits (362), Expect = 6e-33
Identities = 74/174 (42%), Positives = 106/174 (60%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK +E W+ P K++ED+ + + G+++ PWS+ L E I DHL +N
Sbjct: 378 RQSGKKSLELWSTP-KTIEDVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNR 435
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
K +TINSQP +NG +S+ GWG GYVYQK YLEF EK++ L ++ LT
Sbjct: 436 KMIITINSQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLT 495
Query: 393 YMAV-NKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y AV NK+ + ++ + NAVTWG+FP +E++QPTIV+ VSF WK+E + I
Sbjct: 496 YFAVDNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFYRI 549
[108][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 143 bits (361), Expect = 8e-33
Identities = 76/181 (41%), Positives = 108/181 (59%), Gaps = 8/181 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K+ + W P +S +D+ + L++ PWS+ + +T II D L +N
Sbjct: 111 RQSPKRAFDLWGCP-QSFKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQ 168
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR- 380
+GFLT+NSQP++N KS+ GWG GYV+QK YLEFFC ++ KL +EK ++
Sbjct: 169 RGFLTMNSQPSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKG 228
Query: 381 ----PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFX 548
FLTY A +K G +N + D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 229 GESCSFLTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYR 288
Query: 549 I 551
+
Sbjct: 289 L 289
[109][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 143 bits (361), Expect = 8e-33
Identities = 76/181 (41%), Positives = 108/181 (59%), Gaps = 8/181 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K+ + W P +S +D+ + L++ PWS+ + +T II D L +N
Sbjct: 111 RQSPKRAFDLWGCP-QSFKDLSNLVVSYLKNDLKSLPWSD-GPIGEDTAIIVDKLISLNQ 168
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDR- 380
+GFLT+NSQP++N KS+ GWG GYV+QK YLEFFC ++ KL +EK ++
Sbjct: 169 RGFLTMNSQPSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKG 228
Query: 381 ----PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFX 548
FLTY A +K G +N + D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 229 GESCSFLTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYR 288
Query: 549 I 551
+
Sbjct: 289 L 289
[110][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 143 bits (360), Expect = 1e-32
Identities = 72/161 (44%), Positives = 101/161 (62%), Gaps = 14/161 (8%)
Frame = +3
Query: 126 KLRTNPWSELD-GLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY 302
K+ PW+E + G+QPET +I++ L N G LT+NSQP+VNG S P VGWG PGGY
Sbjct: 514 KVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGY 573
Query: 303 VYQKAYLEFFCSKEKLDALVE-KTKDRPF-LTYMAVNKE-----------GVWKSNVGQT 443
YQKAYLE F + E + L++ ++ P + Y A++K+ ++++N +T
Sbjct: 574 CYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNSHDSMQIFRTNSEET 633
Query: 444 DVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
AVTWGVFP EI QPT+VDP+SF W+DEA+ +W W
Sbjct: 634 TPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQW 674
[111][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 142 bits (359), Expect = 1e-32
Identities = 75/179 (41%), Positives = 106/179 (59%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ D+ F F G+L PWS+ + E I D L ++N
Sbjct: 366 KGTNEQNIKLWGEP-KSIRDLAHIFVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNK 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+G TINSQPAVNG +S P GWG G+VYQKAYLE LD L+ + + LT
Sbjct: 424 RGLFTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
Y AV+K G ++N + NA+TWG+F +E++QPTIV+ +SF WKDEA+ + WA
Sbjct: 484 YHAVSKTGELRTNT-RDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWA 540
[112][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 142 bits (358), Expect = 2e-32
Identities = 76/184 (41%), Positives = 108/184 (58%), Gaps = 9/184 (4%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K+ E W +P +++ DI + G+L + PW + + +T II DHL ++N
Sbjct: 371 RQSPKRAQELWGLP-QTISDITGLVISYLKGQLNSLPWFD-GAIGEDTNIILDHLIELNE 428
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK----LDALVEKTKDR 380
+T+NSQP++N +S GWG GYVYQK YLEFFC K+ LD + + K++
Sbjct: 429 NSLITLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQ 488
Query: 381 -----PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAF 545
++Y AVNK G SN D+NAVTWGVFP +EI+QPTIV+ SF WKDE +
Sbjct: 489 GDSTSAVISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVY 548
Query: 546 XIWS 557
++S
Sbjct: 549 TLFS 552
[113][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 142 bits (357), Expect = 2e-32
Identities = 77/173 (44%), Positives = 102/173 (58%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +++ I+ W P KS+ D+ F F GKL PWS+ + E I L +N
Sbjct: 366 KGTNEQNIKLWGEP-KSLRDLTHIFVNFLEGKLARLPWSDTP-ITTEANAIKTSLIDLNQ 423
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
KG TINSQPAVNG KS P GWG GYVYQKAYLE +D L+ + + LT
Sbjct: 424 KGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLT 483
Query: 393 YMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y AV+K G ++N + NA+TWG+F +EI+QPTIV+ VSF WKDEA+ +
Sbjct: 484 YHAVSKTGELRTNT-RDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL 535
[114][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 140 bits (353), Expect = 7e-32
Identities = 74/174 (42%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K +E W+ P S+ D+ + G L+ PWS++ + E I HL ++N
Sbjct: 378 RQSANKCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQ 435
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+TINSQP VNG +S+ GWG GYVYQK YLEF K KL L++ K+ FLT
Sbjct: 436 HSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLT 495
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A++ +G SN + NAVTWG+FP +EI+QPTIV+ +SF WK+E + I
Sbjct: 496 YFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[115][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 140 bits (353), Expect = 7e-32
Identities = 74/174 (42%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K +E W+ P S+ D+ + G L+ PWS++ + E I HL ++N
Sbjct: 189 RQSANKCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQ 246
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+TINSQP VNG +S+ GWG GYVYQK YLEF K KL L++ K+ FLT
Sbjct: 247 HSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLT 306
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A++ +G SN + NAVTWG+FP +EI+QPTIV+ +SF WK+E + I
Sbjct: 307 YFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 360
[116][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 140 bits (353), Expect = 7e-32
Identities = 74/174 (42%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K +E W+ P S+ D+ + G L+ PWS++ + E I HL ++N
Sbjct: 378 RQSANKCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQ 435
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+TINSQP VNG +S+ GWG GYVYQK YLEF K KL L++ K+ FLT
Sbjct: 436 HSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLT 495
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A++ +G SN + NAVTWG+FP +EI+QPTIV+ +SF WK+E + I
Sbjct: 496 YFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[117][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 140 bits (353), Expect = 7e-32
Identities = 74/174 (42%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K +E W+ P S+ D+ + G L+ PWS++ + E I HL ++N
Sbjct: 378 RQSANKCLELWSTPT-SINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQ 435
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
+TINSQP VNG +S+ GWG GYVYQK YLEF K KL L++ K+ FLT
Sbjct: 436 HSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLT 495
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y A++ +G SN + NAVTWG+FP +EI+QPTIV+ +SF WK+E + I
Sbjct: 496 YFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI 549
[118][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 140 bits (352), Expect = 9e-32
Identities = 79/187 (42%), Positives = 110/187 (58%), Gaps = 4/187 (2%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIIN 188
Y+ + A D++ + W + + + + F F G+++ PW + ET I
Sbjct: 343 YSKETQEKVAADRRRM--WGDHVPNGDHVRRVFTDFIKGEVKRLPWCTEPPTE-ETLFIQ 399
Query: 189 DHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK 368
L ++N LTINSQP VNG S P VGWG GG+VYQKAY+EFFC + +L+ L+
Sbjct: 400 KQLIRLNQCNMLTINSQPRVNGALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRG 459
Query: 369 TKDRPF--LTYMAVNKEG-VWKSNV-GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKD 536
+ + ++YMAV +G +SN+ Q VNAVTWGVFP EIIQPT+VD SF WKD
Sbjct: 460 IEAEKYDSISYMAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKD 519
Query: 537 EAFXIWS 557
EAF +W+
Sbjct: 520 EAFALWN 526
[119][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 139 bits (351), Expect = 1e-31
Identities = 77/182 (42%), Positives = 104/182 (57%), Gaps = 13/182 (7%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P ++ EDI F G+L T PWSE +G PET I D L K+N+KG+ ++ SQP
Sbjct: 471 WGTP-RTTEDINNVFIRHLKGELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQP 528
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAVNKE 413
AVNG +S PT GWG G+V+QKA++EFF L +K + + + + A+N
Sbjct: 529 AVNGLRSSDPTFGWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAA 588
Query: 414 GVWKSN----------VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
G + S+ + NAVTWGVFP KEI+ PTI++ VSF W +EAF IW
Sbjct: 589 GDFVSSDTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGE- 647
Query: 564 WA 569
WA
Sbjct: 648 WA 649
[120][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 139 bits (350), Expect = 1e-31
Identities = 75/178 (42%), Positives = 102/178 (57%), Gaps = 3/178 (1%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
KK + W P KSV D+ F + G + PW +L GL PET +I + L ++N +G+L
Sbjct: 429 KKAYDLWGTP-KSVIDLKSVFIKYLEGSISALPWCDL-GLSPETALIQEELIQLNQRGYL 486
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTY 395
T+ SQPA N S GWG GYVYQKA++E F K++ +A+V+ D R +Y
Sbjct: 487 TLASQPATNASPSTDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSY 546
Query: 396 MAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
+ G ++SN+ N VTWGVFP +IQ TIV+ SF W+DEAF IW WA
Sbjct: 547 YVGDSSGSFESNLETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIWLE-WA 603
[121][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 138 bits (348), Expect = 3e-31
Identities = 75/155 (48%), Positives = 97/155 (62%), Gaps = 4/155 (2%)
Frame = +3
Query: 105 FRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGW 284
F F G+++ PW + ET I L ++N LTINSQP VNG S P VGW
Sbjct: 352 FTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGW 410
Query: 285 GGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--LTYMAVNKEG-VWKSNV-GQTDVN 452
G GG+VYQKAY+EFFC + +L+ L+ + + ++YMAV +G +SN+ Q VN
Sbjct: 411 GPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVN 470
Query: 453 AVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
AVTWGVFP EIIQPT+VD SF WKDEAF +W+
Sbjct: 471 AVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN 505
[122][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 138 bits (348), Expect = 3e-31
Identities = 72/175 (41%), Positives = 105/175 (60%), Gaps = 5/175 (2%)
Frame = +3
Query: 60 EWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQ 239
+W P +S+ D+ + F + GK+ PW++ L PET +I + L ++N KG+ ++ SQ
Sbjct: 426 KWGTP-ESIADLTQVFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 240 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 419
PAVNG KS GWG G +YQK+++E F KE L+ K + +TY NK+G
Sbjct: 484 PAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGE 543
Query: 420 WKSNVG-----QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
KSN+ + NAVTWGVFP+KE++QPT++D SF W +EAF +W WA
Sbjct: 544 IKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWLE-WA 597
[123][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 138 bits (348), Expect = 3e-31
Identities = 72/175 (41%), Positives = 105/175 (60%), Gaps = 5/175 (2%)
Frame = +3
Query: 60 EWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQ 239
+W P +S+ D+ + F + GK+ PW++ L PET +I + L ++N KG+ ++ SQ
Sbjct: 426 KWGTP-ESIADLTQVFINYLSGKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 240 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 419
PAVNG KS GWG G +YQK+++E F KE L+ K + +TY NK+G
Sbjct: 484 PAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGE 543
Query: 420 WKSNVG-----QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
KSN+ + NAVTWGVFP+KE++QPT++D SF W +EAF +W WA
Sbjct: 544 IKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWLE-WA 597
[124][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 137 bits (346), Expect = 4e-31
Identities = 79/174 (45%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK +E W+ P S+EDI + + G+L+ PWS+ L E I L +N
Sbjct: 377 RQSGKKSLELWSAP-NSMEDIAQLVINYLRGELKYLPWSDTS-LNHEVDDILPELVTLNQ 434
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
K +TINSQP +NG KS P GWG GYVYQK YLEF KEKL L + + LT
Sbjct: 435 KLIITINSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLT 494
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
Y AV+ G +N T NAVTWG+FP +E++QPTIV+ VSF WK E + I
Sbjct: 495 YFAVDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHI 548
[125][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 137 bits (345), Expect = 6e-31
Identities = 73/164 (44%), Positives = 95/164 (57%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P++ +DI FR G L PWSE GL PET I+ L +N KG+ T+ SQP
Sbjct: 447 WGYPVEK-KDISTLFRRHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQP 504
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVNG KS P GWG GYV+QK ++EFF + A K + +T+ A N G +
Sbjct: 505 AVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAF 564
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
+++ + VN VTWG F KEI+ PTI++ VSF W DEAF IW
Sbjct: 565 EAS-QEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW 607
[126][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 136 bits (342), Expect = 1e-30
Identities = 74/168 (44%), Positives = 96/168 (57%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P+ +DI FR G+L PWSE GL PET I L +N KG+ T+ SQP
Sbjct: 337 WGHPVDK-QDISALFRKHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQP 394
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVNG +S P GWG GYV+QK ++EFF + AL + +TY A N G +
Sbjct: 395 AVNGVRSTDPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDF 454
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
+++ + VN VTWG F KEI+ PTI++ VSF W +EAF IW R W
Sbjct: 455 EAS-SEESVNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REW 500
[127][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 135 bits (340), Expect = 2e-30
Identities = 73/174 (41%), Positives = 109/174 (62%), Gaps = 6/174 (3%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLG--KLRTNPWSELDGLQPETKIINDHLEKINTKGFL- 224
++EW VP+ S D+ F + K T P+ +L L PE+ +I HL +N+
Sbjct: 414 LKEWGVPV-STSDLSALFTAYLHSDPKHLTTPFCDLP-LSPESHMILPHLLALNSANVQH 471
Query: 225 -TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTK--DRPFLTY 395
T+ SQPAV+ KS+ VGWG GGYV+QKA++EFF ++++++ L EK + + +T
Sbjct: 472 WTVGSQPAVDAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITM 531
Query: 396 MAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
A N++G +K+N + VNAVTWGVFP +EI Q TI++ SF WK+EAF IW+
Sbjct: 532 YAANRKGDFKTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA 585
[128][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 135 bits (340), Expect = 2e-30
Identities = 75/178 (42%), Positives = 107/178 (60%), Gaps = 4/178 (2%)
Frame = +3
Query: 42 DKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGF 221
D ++ W P +++ D+ F +C KL PWS++ L E+ II D L ++N +G
Sbjct: 377 DAEIRALWGSP-ENIRDLGNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAELNRQGI 434
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMA 401
LTINSQP V S P GWG GYV+QKAYLEFF +++ +L+E + Y
Sbjct: 435 LTINSQPPVCAAPSTDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYYI 494
Query: 402 VNKEGVWKSNVGQTDV-NAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSRA 563
+ EG ++N G+ DV +AVTWGVFP E+IQPT+V+ SF WKDEA+ + W++A
Sbjct: 495 TDYEGSLETN-GELDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAYSLGLSWAKA 551
[129][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 135 bits (340), Expect = 2e-30
Identities = 70/174 (40%), Positives = 105/174 (60%), Gaps = 2/174 (1%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
+++W P K+ +D+ F ++ P+S + L PE+ I HLE++ +G+ T+
Sbjct: 399 LQQWGYP-KTFDDLTRIFLAHLHSEIPITPFSPTE-LCPESITILPHLERLTKRGWWTVG 456
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR--PFLTYMAVN 407
SQPAV+G S T GWG GYV+QK ++EFFC ++A+ ++ K R ++ Y N
Sbjct: 457 SQPAVDGISSSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMAN 516
Query: 408 KEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
G +SNV + NAVTWGVFP +EI Q TI++ SF WKDEA+ IW+ +WA
Sbjct: 517 NNGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWA 569
[130][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 134 bits (338), Expect = 4e-30
Identities = 72/173 (41%), Positives = 101/173 (58%), Gaps = 3/173 (1%)
Frame = +3
Query: 48 KLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLT 227
+ +E W P+ D+ + F +GKL PWS+ L PET +I + L ++N KG T
Sbjct: 411 RALELWGYPVDDA-DLSKLFADTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWT 468
Query: 228 INSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE---KLDALVEKTKDRPFLTYM 398
+ SQPA N KSD GWG GGYV+QK++ EFF S E KL L++ +D ++Y
Sbjct: 469 VASQPACNALKSDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQED--LVSYY 526
Query: 399 AVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
+ + +NV + N VTWGVFP +EI+Q TI+ SF W++EAF IWS
Sbjct: 527 VAKSDKLVDTNVSERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS 579
[131][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 134 bits (338), Expect = 4e-30
Identities = 71/179 (39%), Positives = 105/179 (58%), Gaps = 6/179 (3%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R K+ E W P +++ D+ + + +++ PWS+ + +T ++ D L +N
Sbjct: 373 RQSPKRAYELWGCP-QTLNDLSDIIVSYLNNEVKALPWSD-GPIGEDTTVLKDALIALNR 430
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE-----KTKD 377
KG T+NSQPA++ +S+ GWG G+VYQK YLEF K+KL L++ KD
Sbjct: 431 KGLFTLNSQPALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKD 490
Query: 378 R-PFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
+TY AV+K G +N D+NAVTWGVFP +EI+QPTIV+ VSF WKDE + +
Sbjct: 491 TYGLITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSL 549
[132][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 134 bits (337), Expect = 5e-30
Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +K+ E W P S+ D+ F + G +++ PW +L GL PET +I + L ++N
Sbjct: 425 KVSNKRAYELWGSPT-SIRDLKAVFVKYLEGSIQSLPWCDL-GLSPETALIQEELIQLNY 482
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RP 383
+G+LT+ SQP N S GWG G+VYQKA++E F +++ +++ D R
Sbjct: 483 RGYLTLASQPCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRR 542
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
+Y A + +G +++N+ N VTWGVFP ++IQ TI++ SF W+DEAF IWS
Sbjct: 543 KFSYYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWSE- 601
Query: 564 WA 569
WA
Sbjct: 602 WA 603
[133][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 134 bits (336), Expect = 6e-30
Identities = 77/175 (44%), Positives = 101/175 (57%), Gaps = 2/175 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R KK IE W+ P ++++D+ + GKL+ PWS++ L E I HL +N
Sbjct: 380 RQSVKKSIELWSTP-QTLDDMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNK 437
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDR-PFL 389
TINSQP VNG+ S P VGWG GYVYQK YLEF +EKL E ++ L
Sbjct: 438 HHIFTINSQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHL 497
Query: 390 TYMAVNKEGVWKSNVGQ-TDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
TY A++ + +N + + NAVTWGVFP EI+QPTIV+ SF WK+E F I
Sbjct: 498 TYFAIDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFFTI 552
[134][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 134 bits (336), Expect = 6e-30
Identities = 78/180 (43%), Positives = 96/180 (53%), Gaps = 4/180 (2%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R ++ +E W+ P K DI + GKL+ PW ++ L E L +N
Sbjct: 376 RQSPQRALELWSTPTK-FSDIAALVIDYLHGKLKCLPWCDV-ALNHEVDTTMPQLLDLNK 433
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLT 392
LT+NSQP VNG S VGWG GYVYQK YLEF K KL L + D P LT
Sbjct: 434 HMILTLNSQPRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLT 493
Query: 393 YMAVNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI---WSR 560
Y AV+ SN T NAVTWG+FP +E++QPTIV+ VSF WK+E F I W R
Sbjct: 494 YFAVDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDILDEWKR 553
[135][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 134 bits (336), Expect = 6e-30
Identities = 69/175 (39%), Positives = 104/175 (59%), Gaps = 5/175 (2%)
Frame = +3
Query: 60 EWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQ 239
+W P +S+ D+ F + GK+ PW++ L PET +I + L ++N KG+ ++ SQ
Sbjct: 426 KWGTP-ESLADLTRVFINYLSGKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQ 483
Query: 240 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 419
PA+NG KS GWG G +YQK+++E F KE L+ K + +TY +K+G
Sbjct: 484 PAINGCKSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGE 543
Query: 420 WKSNV-----GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
+SN+ + NAVTWGVFP+KE++QPT++D SF W +EAF +W WA
Sbjct: 544 IRSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWVE-WA 597
[136][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 133 bits (334), Expect = 1e-29
Identities = 73/177 (41%), Positives = 107/177 (60%), Gaps = 4/177 (2%)
Frame = +3
Query: 51 LIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTI 230
++ +W P KS++D+ + F K+ T P+S L E+ +I HLE++ + + T+
Sbjct: 383 VLAQWNNP-KSLDDLTQIFLGHLHAKILTTPFSPTP-LSSESLMILPHLERLTRRSWWTV 440
Query: 231 NSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTK--DRPFLTYMAV 404
SQPAV+G S VGWG GGYV+QK ++EFFC ++ +D + + + ++ Y A
Sbjct: 441 GSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAG 500
Query: 405 N--KEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
N +G +SNV + NAVTWGVFP +EI Q TI++ SF WKDEAF IWS WA
Sbjct: 501 NYKADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWSE-WA 556
[137][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 132 bits (333), Expect = 1e-29
Identities = 69/176 (39%), Positives = 99/176 (56%), Gaps = 2/176 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +KK + W P ++ DI F + G + PW +L GL PET +I + L +N
Sbjct: 416 KVSNKKAYQIWGYP-STLNDIKSLFIGYLEGSIEALPWCDL-GLSPETALIQEELIGLNQ 473
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP--F 386
+GFLT+ SQPA N S GWG PGG VYQKA++E F K + +A ++ + P
Sbjct: 474 RGFLTLASQPATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSK 533
Query: 387 LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
+Y + G + SN+ + VTWGVFP +I+Q TI++ SF W+DEAF IW
Sbjct: 534 FSYYFGDSAGSFASNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW 589
[138][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 132 bits (332), Expect = 2e-29
Identities = 75/171 (43%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
++ +E W+ P +++ D+ + G L+ PWS++ L E + D L ++N L
Sbjct: 383 QRSLELWSTP-RTLLDLAALVISYLKGDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVL 440
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDAL-VEKTKDRPFLTYMA 401
TINSQP VNG S P VGWG GYVYQK YLEF K L A T D P LTY A
Sbjct: 441 TINSQPKVNGAPSADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFA 500
Query: 402 VNKEGVWKSN-VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
V+ + SN T NAVTWG+FP +E++QPTIV+ SF WKDE + I
Sbjct: 501 VDADDNLASNHPDDTQANAVTWGIFPGREVLQPTIVEKASFLAWKDEFYRI 551
[139][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 132 bits (332), Expect = 2e-29
Identities = 73/184 (39%), Positives = 106/184 (57%), Gaps = 9/184 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
++ I +W P +SV +I + F + GK+ + PW + L PET +I + L ++N KG+
Sbjct: 418 EEAIHKWGAP-ESVNEIIKVFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWF 475
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLT 392
++ SQPAVNG S GWG G +YQKA++E F K+ KL ++K D +T
Sbjct: 476 SLASQPAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTIT 535
Query: 393 YMAVNKEGVWKSNVG-----QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
Y + EG SN+ NA+TWGVFP+KE++QPTI+D SF W +EAF +W
Sbjct: 536 YYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILWL 595
Query: 558 RAWA 569
WA
Sbjct: 596 E-WA 598
[140][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 132 bits (332), Expect = 2e-29
Identities = 74/184 (40%), Positives = 103/184 (55%), Gaps = 5/184 (2%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ +KK E W P K+++D+ F + G + PW +L GL PET +I + L ++N
Sbjct: 429 KVSNKKAYELWGQP-KTIQDLQIIFIKYLEGSIDALPWCDL-GLSPETALIQEELIQLNE 486
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE-----KLDALVEKTKD 377
+GFLT+ SQPA NG S + GWG G VYQKA++E F K + +E+
Sbjct: 487 RGFLTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQ-YG 545
Query: 378 RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
R LTY A + +G +++N+ N VTWGVF ++IQ TIV SF W DEAF IW
Sbjct: 546 RAKLTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIWL 605
Query: 558 RAWA 569
WA
Sbjct: 606 E-WA 608
[141][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 132 bits (331), Expect = 2e-29
Identities = 71/177 (40%), Positives = 101/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ KK E W P S +DI F + G L PWS+L GL ET +I + L ++N
Sbjct: 441 KVSSKKAYEIWGQP-SSTDDIKTLFIRYLEGSLEALPWSDL-GLSAETALIQEELIQLNE 498
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-- 386
+G+L++ SQPA N S GWG PGGYVYQK+++E F K++ + L K K P
Sbjct: 499 RGYLSLASQPATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVHKQQWE-LEIKPKLEPLGS 557
Query: 387 -LTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
++Y + + +N+ + + VTWGVFP E++Q TIV+ SF W+DEAF IW
Sbjct: 558 KVSYYVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW 614
[142][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 131 bits (330), Expect = 3e-29
Identities = 73/184 (39%), Positives = 105/184 (57%), Gaps = 9/184 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
++ I +W P +SV +I + F + GK+ + PW + L PET +I + L ++N KG+
Sbjct: 418 EEAIHKWGAP-ESVNEIIKVFVSYLSGKIDSLPWVDA-ALSPETALIQEELFEVNNKGWF 475
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLT 392
++ SQPAVNG S GWG G +YQKA++E F K+ KL ++K D +T
Sbjct: 476 SLASQPAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTIT 535
Query: 393 YMAVNKEGVWKSNVG-----QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
Y + EG SN+ NA+TWGVFP KE++QPTI+D SF W +EAF +W
Sbjct: 536 YYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILWL 595
Query: 558 RAWA 569
WA
Sbjct: 596 E-WA 598
[143][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 131 bits (330), Expect = 3e-29
Identities = 69/169 (40%), Positives = 104/169 (61%), Gaps = 3/169 (1%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINS 236
E W P+ S+EDI F + G ++ PWS+L GL ET I + L ++N +G+L++ S
Sbjct: 438 ELWDHPV-SLEDIKNIFIRYLEGSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLAS 495
Query: 237 QPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLTYMAVN 407
QPA NG +S GWG G +YQKA++E F KE+ + +++ ++K+ F Y+ +
Sbjct: 496 QPATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLG-D 554
Query: 408 KEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
G +++N+ NAVTWGVFP E++Q TIV+ SF W+DEAF IW
Sbjct: 555 YTGYFETNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIW 603
[144][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1CZX0_NEOFI
Length = 716
Score = 131 bits (329), Expect = 4e-29
Identities = 78/187 (41%), Positives = 105/187 (56%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHLEK-INTKGF 221
W P+ S EDI FR G L PWSE GL ET++I L K I++KG+
Sbjct: 471 WGYPV-SREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGW 529
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPFL 389
T+ SQPAVNG +SD PT GWG PG G+V+QK ++EFFC + +++ L
Sbjct: 530 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKL 589
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 590 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 649
Query: 534 DEAFXIW 554
+EAF IW
Sbjct: 650 EEAFRIW 656
[145][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 130 bits (328), Expect = 5e-29
Identities = 76/185 (41%), Positives = 108/185 (58%), Gaps = 13/185 (7%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
++ W P K+ +DI + F G+L PWSE + L+ E+ I HL ++N KG+ T+
Sbjct: 449 VKLWDYP-KTRQDINDLFVKHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVA 506
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAV 404
SQPAVNG +S T GWG P G+V+QK+++EFF E L A + ++ + ++ + A
Sbjct: 507 SQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYAS 566
Query: 405 NKEGVW-KSNVG---------QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
N G + S++G NAVTWGVFP KEII PTI++ VSF W +EAF IW
Sbjct: 567 NARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIW 626
Query: 555 SRAWA 569
WA
Sbjct: 627 GE-WA 630
[146][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 130 bits (327), Expect = 7e-29
Identities = 73/187 (39%), Positives = 108/187 (57%), Gaps = 9/187 (4%)
Frame = +3
Query: 36 AKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTK 215
A ++ I +W P +SV DI + F + GK+ PW++ L ET +I + L +N +
Sbjct: 410 ASPEEAIAKWGSP-ESVGDIAKVFMGYLSGKIDILPWTD-SSLSAETTLIQEELFDLNDR 467
Query: 216 GFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF--- 386
G+ ++ SQPAVNG KS GWG G VYQKA++E F KE+ ++ ++ + F
Sbjct: 468 GWFSLASQPAVNGCKSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESELKSSLKPHFEEK 527
Query: 387 -LTYMAVNKEGVWKSNV-----GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFX 548
+TY + EG +SN+ NA+TWGVFP+KE++QPTI+D SF W +EAF
Sbjct: 528 TITYYVGDAEGNIESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFL 587
Query: 549 IWSRAWA 569
+W WA
Sbjct: 588 LWIE-WA 593
[147][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 130 bits (326), Expect = 9e-29
Identities = 77/197 (39%), Positives = 105/197 (53%), Gaps = 25/197 (12%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
++ W P K+ EDI + F G+L PWSE +G ET+ I D+L ++N++G+ ++
Sbjct: 446 LQLWGSP-KTTEDINKIFIRHLKGELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLA 503
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRP---------- 383
SQPAVNG +SD T GWG G+V+QKA++EFF L K K
Sbjct: 504 SQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFAT 563
Query: 384 -------------FLTYMAVNKEGVWKSN--VGQTDVNAVTWGVFPAKEIIQPTIVDPVS 518
F MA EG +++ + NAVTWGVFP KEI+ PTI++ VS
Sbjct: 564 NAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVS 623
Query: 519 FSVWKDEAFXIWSRAWA 569
F W +EAF IWS WA
Sbjct: 624 FRAWSEEAFGIWSE-WA 639
[148][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 130 bits (326), Expect = 9e-29
Identities = 64/130 (49%), Positives = 79/130 (60%)
Frame = +3
Query: 162 LQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSK 341
L E I + L +N +G +TINSQPAVNG KS GWG GYVYQK+YLE
Sbjct: 115 LTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHP 174
Query: 342 EKLDALVEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSF 521
+ ++ + + P +TY AV K G K N NAVTWGVFP KEI+QPTIV+ +SF
Sbjct: 175 DLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISF 234
Query: 522 SVWKDEAFXI 551
WKDEAF +
Sbjct: 235 VAWKDEAFRL 244
[149][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 130 bits (326), Expect = 9e-29
Identities = 77/185 (41%), Positives = 102/185 (55%), Gaps = 13/185 (7%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
++ W P K+ +DI + F G+L PWSE + L E+ I HL ++N KG+ T+
Sbjct: 451 VKLWGHP-KTRQDINDLFVKHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVA 508
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAV 404
SQPAVNG +S T GWG P G+V+QK+++EFF + L EK + + A
Sbjct: 509 SQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAG 568
Query: 405 NKEG--VWKSNVGQTD--------VNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
N +G V G D NAVTWGVFP KEII PTI++ VSF W +EAF IW
Sbjct: 569 NAKGDFVSSDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIW 628
Query: 555 SRAWA 569
WA
Sbjct: 629 GE-WA 632
[150][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 129 bits (325), Expect = 1e-28
Identities = 71/184 (38%), Positives = 107/184 (58%), Gaps = 9/184 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
++ I +W P +S +DI + F + GK+ PW + L ET +I + L ++N KG+
Sbjct: 420 QEAIAKWGTP-ESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWF 477
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLT 392
++ SQP+VNG +S GWG G+V+QK+++E F KE KL ++ D +T
Sbjct: 478 SLASQPSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDIT 537
Query: 393 YMAVNKEGVWKSNV-----GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
Y A + G +SN+ NAVTWGVFP++E++QPTI+D SF W +EAF +WS
Sbjct: 538 YYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS 597
Query: 558 RAWA 569
WA
Sbjct: 598 E-WA 600
[151][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 129 bits (324), Expect = 2e-28
Identities = 78/187 (41%), Positives = 104/187 (55%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHLEK-INTKGF 221
W P+ S EDI FR G L PWSE GL ET++I L K I+ KG+
Sbjct: 444 WGYPV-SREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGW 502
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPFL 389
T+ SQPAVNG +SD PT GWG PG G+V+QK ++EFFC + +++ L
Sbjct: 503 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKL 562
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 563 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 622
Query: 534 DEAFXIW 554
+EAF IW
Sbjct: 623 EEAFRIW 629
[152][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 129 bits (323), Expect = 2e-28
Identities = 78/187 (41%), Positives = 104/187 (55%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHLEK-INTKGF 221
W P+ S EDI FR G L PWSE GL ET++I L K I+ KG+
Sbjct: 444 WGYPV-SREDISALFRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGW 502
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPFL 389
T+ SQPAVNG +SD PT GWG PG G+V+QK ++EFFC + +++ L
Sbjct: 503 WTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKL 562
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 563 AWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 622
Query: 534 DEAFXIW 554
+EAF IW
Sbjct: 623 EEAFRIW 629
[153][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 128 bits (322), Expect = 3e-28
Identities = 74/164 (45%), Positives = 94/164 (57%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P+ S DI F G+L+T PWSE + ET I D L +N+KG+ T+ SQP
Sbjct: 453 WGAPV-SPPDISAIFIRHLRGELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLASQP 510
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVNG +S PT GWG G+V+QKA++EFF AL EK +RP EG
Sbjct: 511 AVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAAL-EKRLNRP-------EMEG-- 560
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
+ NAV+WGVFP KEI+ PTI++ VSF W +EAF IW
Sbjct: 561 -RREREASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIW 603
[154][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 128 bits (321), Expect = 3e-28
Identities = 71/178 (39%), Positives = 103/178 (57%), Gaps = 13/178 (7%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT---------- 212
W P+ S+ DI F + K+ PW + L ET I DHL +N
Sbjct: 464 WGHPV-SLTDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAG 521
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCS---KEKLDALVEKTKDRP 383
KG+ ++ SQPAV+G S P VG+G PGG+V+QK+++E F S K++L A ++
Sbjct: 522 KGWWSVGSQPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASA 581
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
+TY A N +G ++SN+G + N VTW VFP KEI+Q TI++ SF W++EAF IW+
Sbjct: 582 PITYFAGNAKGDFQSNLGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA 639
[155][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 128 bits (321), Expect = 3e-28
Identities = 75/195 (38%), Positives = 106/195 (54%), Gaps = 23/195 (11%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
++ W P +VED+ F G L PWSE + ET+ I D L +N++G+ T+
Sbjct: 429 VQLWGRPA-TVEDVSNIFMRHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVA 486
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK-TKDRPFLTYMAVNK 410
SQPAVNG +S+ T GWG G+V+QKA++E F + AL EK ++ + + A N
Sbjct: 487 SQPAVNGLRSNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNA 546
Query: 411 EGVWKSNVGQTD----------------------VNAVTWGVFPAKEIIQPTIVDPVSFS 524
+G ++S+ G D NAVTWGVFP KEI+ PTI++ VSF
Sbjct: 547 KGDFESSDGGGDAPDGAPTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFR 606
Query: 525 VWKDEAFXIWSRAWA 569
W +EAF IW+ WA
Sbjct: 607 AWSEEAFGIWAE-WA 620
[156][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 127 bits (320), Expect = 5e-28
Identities = 78/178 (43%), Positives = 100/178 (56%), Gaps = 6/178 (3%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
I+ W P S DI + F G+L PWSE +GL ET I L +N KG+ T+
Sbjct: 449 IKLWGHP-SSRADITDIFIRHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVA 506
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RPFLTYMAV 404
SQPAVNG KS GWG G+V+QKA++E F +AL K R +++ A
Sbjct: 507 SQPAVNGVKSTDSIFGWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYAS 566
Query: 405 NKEGVWKSN---VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
N +G + S+ +G T NAVTWG FP KEII PTI++ VSF W +EAF IW WA
Sbjct: 567 NAKGDFISSDEAIGST--NAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWGE-WA 621
[157][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 127 bits (320), Expect = 5e-28
Identities = 66/169 (39%), Positives = 95/169 (56%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P+ DI F+ + + PW + + ++ ETK I +L K+N + T+ SQP
Sbjct: 432 WGYPVDE-SDITSLFQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQP 489
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGVW 422
AVNG S P GWG GG V+QKA++E F + + L + K D P +TY A N + +
Sbjct: 490 AVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEF 549
Query: 423 KSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
+N + +AVTWGV+P +EIIQ TI+ VSF W E+F +W WA
Sbjct: 550 LTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWGE-WA 597
[158][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 127 bits (319), Expect = 6e-28
Identities = 79/188 (42%), Positives = 103/188 (54%), Gaps = 24/188 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P+ S +DI + FR G L PWSE GL ET+ I L I+ KG+
Sbjct: 440 WGYPV-STDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGW 498
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPF 386
T+ SQPAVNG +SD P GWG PG G+V+QK ++EFFC K L L++K
Sbjct: 499 WTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEK- 557
Query: 387 LTYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVW 530
L + A N G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 558 LAWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAW 617
Query: 531 KDEAFXIW 554
DEA+ IW
Sbjct: 618 GDEAYRIW 625
[159][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 127 bits (319), Expect = 6e-28
Identities = 75/187 (40%), Positives = 106/187 (56%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHLEK-INTKGF 221
W P+ S +DI FR G+L PWSE GL ET++I L K I+ KG+
Sbjct: 445 WGYPV-SRDDISTLFRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGW 503
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEK---TKDRPFL 389
T+ SQPAVNG +SD+ T GWG PG G+V+QK ++EFFC + + +++ L
Sbjct: 504 WTLASQPAVNGVRSDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKL 563
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 564 AWFATNAKGEFQSSLPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 623
Query: 534 DEAFXIW 554
+EA+ IW
Sbjct: 624 EEAYRIW 630
[160][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 127 bits (318), Expect = 8e-28
Identities = 78/188 (41%), Positives = 105/188 (55%), Gaps = 24/188 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P+ EDI FR G+L PWSE +GL ET II L I+ KG+
Sbjct: 453 WGYPVTR-EDISTLFRRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGW 511
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFC-SKEKLDAL--VEKTKDRPFL 389
T+ SQPA+NG +SD P GWG PG G+V+QK ++EFFC +K+ L L + + L
Sbjct: 512 WTLASQPAINGVRSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKL 571
Query: 390 TYMAVNKEGVWKSN-------------VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVW 530
+ A N +G ++S+ + +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 572 AWFATNVKGDFESSLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAW 631
Query: 531 KDEAFXIW 554
DEA+ IW
Sbjct: 632 GDEAYRIW 639
[161][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 126 bits (317), Expect = 1e-27
Identities = 70/184 (38%), Positives = 105/184 (57%), Gaps = 9/184 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFL 224
++ I +W P +S +DI + F + GK+ PW + L ET +I + L ++N KG+
Sbjct: 420 QEAIAKWGTP-ESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWF 477
Query: 225 TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKE----KLDALVEKTKDRPFLT 392
++ SQP+VNG +S GWG G+V+QK+++E F KE KL ++ D +T
Sbjct: 478 SLASQPSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDIT 537
Query: 393 YMAVNKEGVWKSNV-----GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWS 557
Y A + G +SN+ NAVTWGVFP +E++QPTI+D SF W +EAF +W
Sbjct: 538 YYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLWL 597
Query: 558 RAWA 569
WA
Sbjct: 598 E-WA 600
[162][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 126 bits (317), Expect = 1e-27
Identities = 79/194 (40%), Positives = 105/194 (54%), Gaps = 30/194 (15%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P S EDI + F G+L PWSE GL ET I + L + I+ +G+
Sbjct: 452 WGYPT-SKEDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGW 510
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFL 389
T+ SQPAVNG +SD P GWG G G+V+QKA++EFFCS + + +++ K + L
Sbjct: 511 WTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDEL 570
Query: 390 TYMAVNKEGVWKSNVGQTD-------------------VNAVTWGVFPAKEIIQPTIVDP 512
++ A N G ++S+ T VNAVTWGVF KEII PTI++
Sbjct: 571 SWFATNASGDFQSSSSFTGITGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEE 630
Query: 513 VSFSVWKDEAFXIW 554
VSF W DEAF IW
Sbjct: 631 VSFRAWGDEAFRIW 644
[163][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 126 bits (316), Expect = 1e-27
Identities = 74/176 (42%), Positives = 96/176 (54%), Gaps = 12/176 (6%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P SV DI F G+L PWSE +GL PET II + L ++NT+G+ T+ SQP
Sbjct: 451 WGHPKSSV-DISTLFIKHIRGELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQP 508
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEK---TKDRPFLTYMAVNKE 413
AVNG S T GWG G+V+QKA++E F L E+ + + + A N
Sbjct: 509 AVNGVPSRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGN 568
Query: 414 GVWKSN---------VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
G + ++ NAVTWGVFP KEII PTI++ VSF W +EAF IW
Sbjct: 569 GDFATSDDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIW 624
[164][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 125 bits (313), Expect = 3e-27
Identities = 66/182 (36%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ K +E W +P K++ D+ + F + G PWS+L GL ET +I + L ++N
Sbjct: 435 KVSKSKALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNY 492
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RP 383
+G+LT+ SQPA N S GWG G +YQKA++E F +++ + ++ D R
Sbjct: 493 RGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRR 552
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
+Y A + G +++N+ + VTWGVFP + Q TI++ SF W+DEAF IWS
Sbjct: 553 KFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE- 611
Query: 564 WA 569
WA
Sbjct: 612 WA 613
[165][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 125 bits (313), Expect = 3e-27
Identities = 66/182 (36%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ K +E W +P K++ D+ + F + G PWS+L GL ET +I + L ++N
Sbjct: 435 KVSKSKALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNY 492
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RP 383
+G+LT+ SQPA N S GWG G +YQKA++E F +++ + ++ D R
Sbjct: 493 RGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRR 552
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
+Y A + G +++N+ + VTWGVFP + Q TI++ SF W+DEAF IWS
Sbjct: 553 KFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE- 611
Query: 564 WA 569
WA
Sbjct: 612 WA 613
[166][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 125 bits (313), Expect = 3e-27
Identities = 66/182 (36%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ K +E W +P K++ D+ + F + G PWS+L GL ET +I + L ++N
Sbjct: 435 KVSKSKALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNY 492
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RP 383
+G+LT+ SQPA N S GWG G +YQKA++E F +++ + ++ D R
Sbjct: 493 RGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRR 552
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
+Y A + G +++N+ + VTWGVFP + Q TI++ SF W+DEAF IWS
Sbjct: 553 KFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE- 611
Query: 564 WA 569
WA
Sbjct: 612 WA 613
[167][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 125 bits (313), Expect = 3e-27
Identities = 66/182 (36%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
+ K +E W +P K++ D+ + F + G PWS+L GL ET +I + L ++N
Sbjct: 435 KVSKSKALELWGIP-KTIGDLKDIFIKYLEGSTDAIPWSDL-GLSAETALIQEELIQLNY 492
Query: 213 KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKD---RP 383
+G+LT+ SQPA N S GWG G +YQKA++E F +++ + ++ D R
Sbjct: 493 RGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRR 552
Query: 384 FLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRA 563
+Y A + G +++N+ + VTWGVFP + Q TI++ SF W+DEAF IWS
Sbjct: 553 KFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE- 611
Query: 564 WA 569
WA
Sbjct: 612 WA 613
[168][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 124 bits (311), Expect = 5e-27
Identities = 78/198 (39%), Positives = 101/198 (51%), Gaps = 34/198 (17%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE-----LDGLQPETKIINDHL-EKINTKGFL 224
W P EDI F+ G L PWSE GL ET I D L + IN +G+
Sbjct: 449 WGYPTTK-EDINTIFQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWW 507
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLT 392
T+ SQPAVNG ++D P GWG G G+V+QKA++EFFC+ L +++ + L
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELA 567
Query: 393 YMAVNKEGVWKSN------------------------VGQTDVNAVTWGVFPAKEIIQPT 500
+ A N G ++S+ G T VNAVTWGVF KEI+ PT
Sbjct: 568 WFATNAAGDFESSSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPT 627
Query: 501 IVDPVSFSVWKDEAFXIW 554
I++ VSF W DEAF IW
Sbjct: 628 IIEEVSFRAWGDEAFRIW 645
[169][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 123 bits (309), Expect = 8e-27
Identities = 74/187 (39%), Positives = 101/187 (54%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P+ +DI FR G+L PWSE GL PET+ I L + I+ KG+
Sbjct: 452 WGYPVTR-DDINTLFRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGW 510
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKTKDR---PFL 389
T+ SQPAVNG +SD P GWG P G+V+QK ++EFFC + ++ + L
Sbjct: 511 WTLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKL 570
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N G ++S++ +VNAVTWGVF KEI+ PTI++ VSF W
Sbjct: 571 AWFATNANGDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWG 630
Query: 534 DEAFXIW 554
DEA+ IW
Sbjct: 631 DEAYRIW 637
[170][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 123 bits (309), Expect = 8e-27
Identities = 78/194 (40%), Positives = 104/194 (53%), Gaps = 30/194 (15%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P S EDI + F G+L PWSE GL ET I + L + I+ +G+
Sbjct: 452 WGYPT-SREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGW 510
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFL 389
T+ SQPAVNG +SD P GWG G G+V+QKA++EFFCS + + +++ K + L
Sbjct: 511 WTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDEL 570
Query: 390 TYMAVNKEGVWKSNVGQTD-------------------VNAVTWGVFPAKEIIQPTIVDP 512
++ A N G ++S+ T VNAVTWGVF KEII PTI++
Sbjct: 571 SWFATNASGDFQSSSSFTGTTGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEE 630
Query: 513 VSFSVWKDEAFXIW 554
VSF W EAF IW
Sbjct: 631 VSFRAWGHEAFRIW 644
[171][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 123 bits (309), Expect = 8e-27
Identities = 78/194 (40%), Positives = 104/194 (53%), Gaps = 30/194 (15%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P S EDI + F G+L PWSE GL ET I + L + I+ +G+
Sbjct: 452 WGYPT-SREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGW 510
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFL 389
T+ SQPAVNG +SD P GWG G G+V+QKA++EFFCS + + +++ K + L
Sbjct: 511 WTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDEL 570
Query: 390 TYMAVNKEGVWKSNVGQTD-------------------VNAVTWGVFPAKEIIQPTIVDP 512
++ A N G ++S+ T VNAVTWGVF KEII PTI++
Sbjct: 571 SWFATNASGDFQSSSSFTGTTGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEE 630
Query: 513 VSFSVWKDEAFXIW 554
VSF W EAF IW
Sbjct: 631 VSFRAWGHEAFRIW 644
[172][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 123 bits (309), Expect = 8e-27
Identities = 72/179 (40%), Positives = 101/179 (56%), Gaps = 6/179 (3%)
Frame = +3
Query: 33 RAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT 212
R ++ +E WA+P S+ D+ + G+LR PWS+ + E +I L +N
Sbjct: 372 RQSAQRSLELWAMP-SSIRDVAMLVVAYLQGELRCLPWSDTP-VSSEVDVIRRQLIALNE 429
Query: 213 KGFL-TINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSK---EKLDALVEKTKDR 380
+ + TINSQP VNG +S+ GWG GYVYQK YLEF + E+L + KT +
Sbjct: 430 QQLIVTINSQPQVNGLRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNET 489
Query: 381 PF-LTYMAVNKEGVWKSNVGQ-TDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXI 551
LTY+A + G W SN AVTWGVFP +E++QPTIV+ +SF W+DE + I
Sbjct: 490 TSSLTYLAADSHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRI 548
[173][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 123 bits (308), Expect = 1e-26
Identities = 63/170 (37%), Positives = 98/170 (57%), Gaps = 5/170 (2%)
Frame = +3
Query: 60 EWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQ 239
+W P ++ +D+ + F + GK+ PW++ L PET +I + L ++N KG+ ++ SQ
Sbjct: 419 KWGSP-ETTKDLAQIFIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQ 476
Query: 240 PAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKEGV 419
PA N KS GWG G VYQKA++E F K+ + L + +TY A +K
Sbjct: 477 PAANACKSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNK 536
Query: 420 WKSNVG-----QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
++ V + NAVTWGVFP+KE++QPT++D SF W +E+F +W
Sbjct: 537 IEAKVPAGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW 586
[174][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 122 bits (307), Expect = 1e-26
Identities = 81/200 (40%), Positives = 102/200 (51%), Gaps = 36/200 (18%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P EDI FR G L PWSE GL PET I +L I +G+
Sbjct: 450 WGYPTTR-EDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGW 508
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEK----LDALVEKTKDRPF 386
TI SQPAV+G +SD P GWG PG G+V+QKA++EFFCSK+ L L+++ F
Sbjct: 509 WTIASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF 568
Query: 387 LTYMAVNKEGVWKSNVGQT------------------------DVNAVTWGVFPAKEIIQ 494
+ A N G ++S+ + VNAVTWGVF KEII
Sbjct: 569 -AWFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIIT 627
Query: 495 PTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 628 PTIIEEVSFRAWGEEAFRIW 647
[175][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 122 bits (307), Expect = 1e-26
Identities = 80/200 (40%), Positives = 105/200 (52%), Gaps = 36/200 (18%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P S EDI + FR G L PWSE GL PET I +L + I+ +G+
Sbjct: 448 WGFPT-SREDINQIFRRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGW 506
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCS----KEKLDALVEKTKDRPF 386
T+ SQPAVNG +SD T GWG PG G+V+QKA++EFFCS + L L+++ F
Sbjct: 507 WTLASQPAVNGVRSDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEF 566
Query: 387 LTYMAVNKEGVWKSNVGQT------------------------DVNAVTWGVFPAKEIIQ 494
+ A N G ++++ + VNAVTWGVF KEII
Sbjct: 567 -AWFATNAAGDFEASTPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIIT 625
Query: 495 PTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 626 PTIIEEVSFRAWGEEAFRIW 645
[176][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 122 bits (306), Expect = 2e-26
Identities = 63/169 (37%), Positives = 99/169 (58%), Gaps = 5/169 (2%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P +SV D+ F + K+ + PW + L PET +I + L ++N++G T+ SQP
Sbjct: 389 WGTP-QSVADVSRVFIDYLSAKISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQP 446
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSK---EKLDALVEKTKDRPFLTYMAVNKE 413
AV+ S +GWG G ++QK+++EFF K E+L L++K +TY N +
Sbjct: 447 AVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSK 506
Query: 414 GVWKSNV--GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIW 554
G +N+ + A+TWGVFP+KE++QPT++D SF W +EAF +W
Sbjct: 507 GEITTNMPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW 555
[177][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 122 bits (306), Expect = 2e-26
Identities = 77/178 (43%), Positives = 97/178 (54%), Gaps = 6/178 (3%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
I+ W P S DI + F G+L PWSE +GL ET I L +N KG+ T+
Sbjct: 449 IKLWGHP-SSRADITDIFIRHLEGQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVA 506
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF---LTYMAV 404
SQPAVNG KS GWG G+V+QKA++E F L K +++ A
Sbjct: 507 SQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYAS 566
Query: 405 NKEGVWKSN---VGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
N +G + S+ VG T NAVTWG FP KEII PTI++ VSF W +EAF IW WA
Sbjct: 567 NAKGDFISSDEAVGST--NAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWGE-WA 621
[178][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 122 bits (305), Expect = 2e-26
Identities = 73/187 (39%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P+ S EDI F G+L PWSE GL ET++I L + I+ G+
Sbjct: 444 WGFPV-SHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGW 502
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKTKDR---PFL 389
T+ SQPAVNG +SD P GWG P G+V+QK ++EFFC + ++++ + L
Sbjct: 503 WTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKL 562
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VN VTWGVF KEI+ PTI++ VSF W
Sbjct: 563 AWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWG 622
Query: 534 DEAFXIW 554
DEAF IW
Sbjct: 623 DEAFRIW 629
[179][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 122 bits (305), Expect = 2e-26
Identities = 80/200 (40%), Positives = 102/200 (51%), Gaps = 36/200 (18%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P EDI FR G L PWSE GL PET I +L I +G+
Sbjct: 450 WGYPTTR-EDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGW 508
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEK----LDALVEKTKDRPF 386
T+ SQPAV+G +SD P GWG PG G+V+QKA++EFFCSK+ L L+++ F
Sbjct: 509 WTLASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEF 568
Query: 387 LTYMAVNKEGVWKSNVGQT------------------------DVNAVTWGVFPAKEIIQ 494
+ A N G ++S+ + VNAVTWGVF KEII
Sbjct: 569 -AWFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIIT 627
Query: 495 PTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 628 PTIIEEVSFRAWGEEAFRIW 647
[180][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 122 bits (305), Expect = 2e-26
Identities = 66/170 (38%), Positives = 98/170 (57%), Gaps = 2/170 (1%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTINSQP 242
W P+ ++DI + F + ++ PWSEL GL PET +I + L ++N K TI+SQP
Sbjct: 386 WGYPV-DLDDITKIFIAYLSNRITALPWSEL-GLNPETGLIQEELIQLNEKHMFTISSQP 443
Query: 243 AVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKL-DALVEKTKDRPFLTYMAVNKEGV 419
+ NG KS GWG GYVYQKA++E F +K++ + ++ + +T+ +
Sbjct: 444 SANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNA 503
Query: 420 WKSNVG-QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
+ +N+ N+VTWG FP KEI+Q TI+ SF W +EAF IW R W
Sbjct: 504 FDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REW 552
[181][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 122 bits (305), Expect = 2e-26
Identities = 73/187 (39%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE------LDGLQPETKIINDHL-EKINTKGF 221
W P+ S EDI F G+L PWSE GL ET++I L + I+ G+
Sbjct: 492 WGFPV-SHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGW 550
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKTKDR---PFL 389
T+ SQPAVNG +SD P GWG P G+V+QK ++EFFC + ++++ + L
Sbjct: 551 WTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKL 610
Query: 390 TYMAVNKEGVWKSNV------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK 533
+ A N +G ++S++ +VN VTWGVF KEI+ PTI++ VSF W
Sbjct: 611 AWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWG 670
Query: 534 DEAFXIW 554
DEAF IW
Sbjct: 671 DEAFRIW 677
[182][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 119 bits (299), Expect = 1e-25
Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 34/198 (17%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE-----LDGLQPETKIINDHL-EKINTKGFL 224
W P +DI F+ G+L PWSE GL ET I D L + IN +G+
Sbjct: 449 WGYPTTK-QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWW 507
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLT 392
T+ SQPAVNG ++D P GWG G G+V+QKA++EFFC +++++ ++
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 567
Query: 393 YMAVNKEGVWKSNV------------------------GQTDVNAVTWGVFPAKEIIQPT 500
+ A N G + S+ G T V AVTWGVF KEI+ PT
Sbjct: 568 WFATNAAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 627
Query: 501 IVDPVSFSVWKDEAFXIW 554
I++ VSF W DEAF IW
Sbjct: 628 IIEEVSFRAWGDEAFRIW 645
[183][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 119 bits (298), Expect = 2e-25
Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 34/198 (17%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE-----LDGLQPETKIINDHL-EKINTKGFL 224
W P +DI F+ G+L PWSE GL ET I D L + IN +G+
Sbjct: 449 WGYPTTK-QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWW 507
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLT 392
T+ SQPAVNG ++D P GWG G G+V+QKA++EFFC +++++ ++
Sbjct: 508 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 567
Query: 393 YMAVNKEGVWKSNV------------------------GQTDVNAVTWGVFPAKEIIQPT 500
+ A N G + S+ G T V AVTWGVF KEI+ PT
Sbjct: 568 WFATNVAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 627
Query: 501 IVDPVSFSVWKDEAFXIW 554
I++ VSF W DEAF IW
Sbjct: 628 IIEEVSFRAWGDEAFRIW 645
[184][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 119 bits (298), Expect = 2e-25
Identities = 65/177 (36%), Positives = 101/177 (57%), Gaps = 5/177 (2%)
Frame = +3
Query: 54 IEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINTKGFLTIN 233
I +W P +++++ + F + GK+ PW++ L PET +I + L ++N KG+ ++
Sbjct: 409 IAKWGSPT-NIKELGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVA 466
Query: 234 SQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPFLTYMAVNKE 413
SQPAVNG +S+ GWG G VYQK+++E F + L + D TY +K
Sbjct: 467 SQPAVNGCRSNDNVFGWGPGNGVVYQKSFVELFIPAKDWKELKPRLDDA--TTYYVGDKS 524
Query: 414 G-----VWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAWA 569
G ++ + + NAVTWGVFP KE++QPT++D SF W +EAF +W WA
Sbjct: 525 GRIELSLFTNESTRHLKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLWLE-WA 580
[185][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 119 bits (297), Expect = 2e-25
Identities = 74/198 (37%), Positives = 99/198 (50%), Gaps = 34/198 (17%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE-----LDGLQPETKIINDHL-EKINTKGFL 224
W P +DI F+ G+L PWSE GL ET I D L IN +G+
Sbjct: 448 WGYPTTK-QDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWW 506
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVE---KTKDRPFLT 392
T+ SQPAVNG ++D P GWG G G+V+QKA++EFFC +++++ ++
Sbjct: 507 TLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFA 566
Query: 393 YMAVNKEGVWKSNV------------------------GQTDVNAVTWGVFPAKEIIQPT 500
+ A N G + S+ G T V AVTWGVF KEI+ PT
Sbjct: 567 WFATNAAGDFMSSSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPT 626
Query: 501 IVDPVSFSVWKDEAFXIW 554
I++ VSF W DEAF IW
Sbjct: 627 IIEEVSFRAWGDEAFRIW 644
[186][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 118 bits (295), Expect = 4e-25
Identities = 79/200 (39%), Positives = 103/200 (51%), Gaps = 36/200 (18%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSE-----LDGLQPETKIINDHLEK-INTKGFL 224
W P S EDI FR G+L PWSE GL PET I L K + +G+
Sbjct: 410 WGTPT-SREDISNIFRRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWW 468
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKE----KLDALVEKTKDRPFL 389
T+ SQP+VNG ++D P GWG G G+V+QKA++EFFC + KL L+ F
Sbjct: 469 TLASQPSVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEF- 527
Query: 390 TYMAVNKEGVWKSNVG----------------QTD---------VNAVTWGVFPAKEIIQ 494
+ A+N +G ++S+ TD VNAVTWGVF KEI+
Sbjct: 528 AWFAMNAKGDFQSSTSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVT 587
Query: 495 PTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 588 PTIIEAVSFRAWGEEAFGIW 607
[187][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 117 bits (294), Expect = 5e-25
Identities = 54/103 (52%), Positives = 70/103 (67%), Gaps = 1/103 (0%)
Frame = +3
Query: 261 SDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF-LTYMAVNKEGVWKSNVG 437
S P VGWG GGYV+QKAYLEFF S+E ++AL++ K + Y V+ +G +N
Sbjct: 4 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 63
Query: 438 QTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSRAW 566
+ NAVTWG+FP +EIIQPT+VDP+SF WKDEAF +W W
Sbjct: 64 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 106
[188][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 116 bits (290), Expect = 1e-24
Identities = 73/189 (38%), Positives = 102/189 (53%), Gaps = 25/189 (13%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSEL------DGLQPETKIINDHLEK-INTKGF 221
W P+ S +D+ FR G+L PWSE +GL ET++I L K I+ +G+
Sbjct: 443 WGHPVDS-KDMSAIFRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGW 501
Query: 222 LTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPFL 389
T+ SQPAVNG +D P GWG G+V+QK ++EFFCS +++ L
Sbjct: 502 WTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKL 561
Query: 390 TYMAVNKEGVWKSNV--------------GQTDVNAVTWGVFPAKEIIQPTIVDPVSFSV 527
T+ A N +G ++S++ VNAVTWGVF KEI+ PTI++ VSF
Sbjct: 562 TWFATNVKGDFESSLPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRA 621
Query: 528 WKDEAFXIW 554
W +EAF IW
Sbjct: 622 WGEEAFRIW 630
[189][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 115 bits (289), Expect = 2e-24
Identities = 70/196 (35%), Positives = 106/196 (54%), Gaps = 9/196 (4%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTN-------PWSELDGLQ 167
Y + +++ ++ ++L++ W L S E ++E F + G+ N PW++ D L
Sbjct: 397 YYLFYLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLA 455
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEK 347
PET ++ L+K+N +G LTINSQP VNG+ S P VGWG GYV+QKAYLEFF S E
Sbjct: 456 PETNLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEM 515
Query: 348 LDALVEKTKD-RPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIQPT-IVDPVSF 521
+ AL++ K P + Y VN V K +++ G+ P + Q + +
Sbjct: 516 VTALIKVLKRYEPRVNYHIVN---VHKHTQLLKLLSSSDTGMGPVIQNAQDLGNLSVIWI 572
Query: 522 SVWKDEAFXIWSRAWA 569
S+ DEAF +W WA
Sbjct: 573 SITDDEAFALWIEQWA 588
[190][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 110 bits (275), Expect = 7e-23
Identities = 65/182 (35%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Frame = +3
Query: 45 KKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINDHLEKINT---- 212
++ + W P+ +DI F F G+L PW ++ + ET + L +N+
Sbjct: 366 EEAVRLWGTPVDE-DDISSIFSRFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSA 423
Query: 213 --KGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKTKDRPF 386
K + T+ SQPAV+G S PT G+G GGY++QKA++E F ++ +ALV+ +
Sbjct: 424 GGKAWWTVGSQPAVDGCDSTDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSST 483
Query: 387 -LTYMAVNKEGV-WKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWKDEAFXIWSR 560
+TY A + +++N+ +N VTWGVFP E+ Q TI++ SF W+DEAF IW R
Sbjct: 484 PVTYFAGKCDPTTFETNLTTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-R 542
Query: 561 AW 566
W
Sbjct: 543 EW 544
[191][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 107 bits (267), Expect = 6e-22
Identities = 74/202 (36%), Positives = 97/202 (48%), Gaps = 36/202 (17%)
Frame = +3
Query: 57 EEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDG-----LQPETKIINDHL-EKINTKG 218
E W P+ EDI FR G+L PWSE L ET+II L + I K
Sbjct: 450 ELWGFPVTR-EDIGTLFRKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKN 508
Query: 219 FLTINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPF 386
+ T+ SQPAVNG +SD P GWG PG G+V+QKA++EFFC V+ T
Sbjct: 509 WWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEE 568
Query: 387 LTYMAVNKEGVWKSN--------------------------VGQTDVNAVTWGVFPAKEI 488
++ A+N G +S+ V ++ AVTWG F +EI
Sbjct: 569 FSWFAINATGHLESSFLLSASSSPKPEDASSTIAADEEPVEVRESKGMAVTWGAFRGREI 628
Query: 489 IQPTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 629 TTPTIIEEVSFRAWGEEAFRIW 650
[192][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 104 bits (259), Expect = 5e-21
Identities = 71/201 (35%), Positives = 95/201 (47%), Gaps = 37/201 (18%)
Frame = +3
Query: 63 WAVPLKSVEDIYERFRLFCLGKLRTNPWSELDG-----LQPETKIINDHL-EKINTKGFL 224
W P+ EDI FR G+L PWSE L ET+ I L + I K +
Sbjct: 454 WGFPVTR-EDIGALFRKHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKKNWW 512
Query: 225 TINSQPAVNGEKSDSPTVGWGGPG-GYVYQKAYLEFFCSKEKLDALVEKT---KDRPFLT 392
T+ SQPAVNG +SD P GWG PG G+V+QKA++EFFC V+ T +
Sbjct: 513 TLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFS 572
Query: 393 YMAVNKEGVWKSN---------------------------VGQTDVNAVTWGVFPAKEII 491
+ A+N G +S+ + ++ AVTWG F +EI
Sbjct: 573 WFAINAAGHLESSFLISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREIT 632
Query: 492 QPTIVDPVSFSVWKDEAFXIW 554
PTI++ VSF W +EAF IW
Sbjct: 633 TPTIIEEVSFRAWGEEAFRIW 653
[193][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 97.4 bits (241), Expect = 7e-19
Identities = 57/135 (42%), Positives = 76/135 (56%), Gaps = 1/135 (0%)
Frame = +3
Query: 6 LYNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETKII 185
L + QFMRP A DKKL EEW VPLKSVEDI +RF FC GKL+ PW E +GLQP+TKII
Sbjct: 11 LIDYQFMRPHACDKKLQEEWVVPLKSVEDIQKRFMKFCRGKLKNGPWKEFEGLQPDTKII 70
Query: 186 NDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGY-VYQKAYLEFFCSKEKLDALV 362
++ + IN KG P + WGG G ++ K ++ + S+ L+
Sbjct: 71 DEPIGNINLKGKWGKIGLP-----------IWWGGVGQVGMFTKRLMQSYPSR----ILL 115
Query: 363 EKTKDRPFLTYMAVN 407
E+ + FL + N
Sbjct: 116 EEVQSSYFLVSLVDN 130
[194][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 89.7 bits (221), Expect = 1e-16
Identities = 43/89 (48%), Positives = 58/89 (65%)
Frame = +3
Query: 141 PWSELDGLQPETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAY 320
PW++ + L ET I + L N+ G L+INSQP+VN S P +GWGG GGY+YQKAY
Sbjct: 5 PWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAY 63
Query: 321 LEFFCSKEKLDALVEKTKDRPFLTYMAVN 407
LEFF S E + L+++ K+ P + Y VN
Sbjct: 64 LEFFASPEVVYILLQELKNYPQVNYHVVN 92
[195][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 87.8 bits (216), Expect = 5e-16
Identities = 43/109 (39%), Positives = 65/109 (59%), Gaps = 7/109 (6%)
Frame = +3
Query: 9 YNVQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLF-------CLGKLRTNPWSELDGLQ 167
Y + +++ ++ + L++ W L S E ++E F + C K+ PW++ + L
Sbjct: 407 YYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWND-EPLA 465
Query: 168 PETKIINDHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQK 314
ET ++ D LEK+N +G LTINSQP +NG+ S P VGWG GGYVYQK
Sbjct: 466 QETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQK 514