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[1][TOP]
>UniRef100_B9SQS5 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS5_RICCO
Length = 510
Score = 367 bits (943), Expect = e-100
Identities = 178/192 (92%), Positives = 186/192 (96%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KTSVP+E VYSD++ARFLSEYRFDV+KLEPLVAKPHSPDN ALARECKDV
Sbjct: 308 DSTTFKYLEDKTSVPFEPVYSDEKARFLSEYRFDVSKLEPLVAKPHSPDNCALARECKDV 367
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAKVFLASG KKVKVPTFLVPATQKVWMDVYSLPVPGSGG
Sbjct: 368 KIDRVYIGSCTGGKTEDFMAAAKVFLASG-KKVKVPTFLVPATQKVWMDVYSLPVPGSGG 426
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 427 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPMVCVSTTNRNFPGRMGHKEGQIY 486
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 487 LASPYTAAASAL 498
[2][TOP]
>UniRef100_UPI0001983BAD PREDICTED: similar to Os02g0125100 n=1 Tax=Vitis vinifera
RepID=UPI0001983BAD
Length = 508
Score = 367 bits (941), Expect = e-100
Identities = 177/192 (92%), Positives = 185/192 (96%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KT VPYE VYSD+QARFLSEYRFDV+KLEPLVAKPHSPDNRALARECKDV
Sbjct: 306 DSTTHKYLEDKTDVPYEPVYSDEQARFLSEYRFDVSKLEPLVAKPHSPDNRALARECKDV 365
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVF ASG KKVKVPTFLVPATQKVWMDVYSLPVPG GG
Sbjct: 366 KIDRVYIGSCTGGKTEDFLAAAKVFHASG-KKVKVPTFLVPATQKVWMDVYSLPVPGCGG 424
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASPSCGACLGGP+DTYARMNEPQVCVSTTNRNFPGRMGH+EG+IY
Sbjct: 425 KTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQVCVSTTNRNFPGRMGHKEGQIY 484
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 485 LASPYTAAASAL 496
[3][TOP]
>UniRef100_C5XT62 Putative uncharacterized protein Sb04g002120 n=1 Tax=Sorghum
bicolor RepID=C5XT62_SORBI
Length = 507
Score = 364 bits (934), Expect = 3e-99
Identities = 174/192 (90%), Positives = 184/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEGKTSV YE VYSD QARF S+YRFDV+KLEP+VAKPHSPDNRALARECKDV
Sbjct: 305 DETTFKYLEGKTSVDYEPVYSDAQARFFSDYRFDVSKLEPVVAKPHSPDNRALARECKDV 364
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K++RVYIGSCTGGKTEDF+AAAKVFLASG KKVKVPTFLVPATQKVWMDVYSLPVPGSGG
Sbjct: 365 KVDRVYIGSCTGGKTEDFLAAAKVFLASG-KKVKVPTFLVPATQKVWMDVYSLPVPGSGG 423
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASPSCGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 424 KTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQIY 483
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 484 LASPYTAAASAL 495
[4][TOP]
>UniRef100_B9SQS6 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS6_RICCO
Length = 621
Score = 363 bits (931), Expect = 7e-99
Identities = 173/192 (90%), Positives = 184/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KTSVPYE VYSD+QARFLSEYRFD++KLEPLVAKPHSPDNRALARECKDV
Sbjct: 419 DSTTFKYLEDKTSVPYEPVYSDEQARFLSEYRFDISKLEPLVAKPHSPDNRALARECKDV 478
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF AAAKVFLASG KKVKVPTFLVPATQKVWMDVYS+PVPGSGG
Sbjct: 479 KIDRVYIGSCTGGKTEDFTAAAKVFLASG-KKVKVPTFLVPATQKVWMDVYSIPVPGSGG 537
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCS+IFEEAGCDTPASP C AC+GGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 538 KTCSRIFEEAGCDTPASPGCSACMGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQIY 597
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 598 LASPYTAAASAL 609
[5][TOP]
>UniRef100_B9HSU8 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HSU8_POPTR
Length = 462
Score = 363 bits (931), Expect = 7e-99
Identities = 173/192 (90%), Positives = 185/192 (96%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KT++PYE VYSD QARFLSEYRFD++KLEPLVAKPHSPDNRALAREC+DV
Sbjct: 260 DSTTFKYLEDKTTLPYEPVYSDAQARFLSEYRFDISKLEPLVAKPHSPDNRALARECRDV 319
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMA AKVFLASG KKVKVPTFLVPATQKVWMDVY+LPVPGSGG
Sbjct: 320 KIDRVYIGSCTGGKTEDFMAVAKVFLASG-KKVKVPTFLVPATQKVWMDVYTLPVPGSGG 378
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASPSCGACLGGPKDT+ARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 379 KTCAQIFEEAGCDTPASPSCGACLGGPKDTHARMNEPMVCVSTTNRNFPGRMGHKEGQIY 438
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 439 LASPYTAAASAL 450
[6][TOP]
>UniRef100_B9HKV5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HKV5_POPTR
Length = 443
Score = 359 bits (921), Expect = 1e-97
Identities = 171/192 (89%), Positives = 185/192 (96%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KTS+PYE VYSD QARFL+EYRFDVTKLEPLVAKPHSPDNRALARECKDV
Sbjct: 241 DSTTFKYLEDKTSLPYEPVYSDAQARFLTEYRFDVTKLEPLVAKPHSPDNRALARECKDV 300
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAKVFLASG KKV+VPTFLVPAT KVWMD+Y+LPVPGSGG
Sbjct: 301 KIDRVYIGSCTGGKTEDFMAAAKVFLASG-KKVRVPTFLVPATGKVWMDLYTLPVPGSGG 359
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPA+P+CGAC+GGP+DTYARMN+P VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 360 KTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRNFPGRMGHKEGQIY 419
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 420 LASPYTAAASAL 431
[7][TOP]
>UniRef100_B4FG11 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FG11_MAIZE
Length = 505
Score = 358 bits (920), Expect = 1e-97
Identities = 171/192 (89%), Positives = 183/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEGKTSV YE VYSD QARF S+YRFDV+KLEP+VAKPHSPDNRA ARECKDV
Sbjct: 303 DETTFKYLEGKTSVDYEPVYSDAQARFFSDYRFDVSKLEPVVAKPHSPDNRAPARECKDV 362
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVFLASG KKVKVPTFLVPATQKVW+D+YSLPVPGSGG
Sbjct: 363 KIDRVYIGSCTGGKTEDFLAAAKVFLASG-KKVKVPTFLVPATQKVWLDIYSLPVPGSGG 421
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASP+CGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 422 KTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQIY 481
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 482 LASPYTAAASAL 493
[8][TOP]
>UniRef100_C4JBG7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4JBG7_MAIZE
Length = 505
Score = 358 bits (919), Expect = 2e-97
Identities = 170/192 (88%), Positives = 184/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEG+TSV Y+ VYSD +ARF S+YRFDV+KLEP+VAKPHSPDNRALARECKDV
Sbjct: 303 DETTFKYLEGRTSVDYQPVYSDAEARFFSDYRFDVSKLEPVVAKPHSPDNRALARECKDV 362
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVFLASG KKVKVPTFLVPATQKVWMDVYSLPVPGSGG
Sbjct: 363 KIDRVYIGSCTGGKTEDFLAAAKVFLASG-KKVKVPTFLVPATQKVWMDVYSLPVPGSGG 421
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASP+CGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 422 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQIY 481
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 482 LASPYTAAASAL 493
[9][TOP]
>UniRef100_Q6Z702 Os02g0125100 protein n=2 Tax=Oryza sativa RepID=Q6Z702_ORYSJ
Length = 514
Score = 358 bits (918), Expect = 2e-97
Identities = 169/192 (88%), Positives = 183/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ YLEGKTSV YE VYSD QARF+S+YRFDV+KLEP++AKPHSPDNRALARECKDV
Sbjct: 312 DQTTFNYLEGKTSVEYEPVYSDAQARFVSDYRFDVSKLEPVIAKPHSPDNRALARECKDV 371
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF AAAKVFLASG KKVKVPTFLVPATQKVWMD+YS+PVPG+GG
Sbjct: 372 KIDRVYIGSCTGGKTEDFFAAAKVFLASG-KKVKVPTFLVPATQKVWMDIYSIPVPGAGG 430
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASPSCGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 431 KTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPMVCVSTTNRNFPGRMGHKEGQIY 490
Query: 542 LASPYTAAASAL 577
LASP+TAAASAL
Sbjct: 491 LASPFTAAASAL 502
[10][TOP]
>UniRef100_B6U6T6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6U6T6_MAIZE
Length = 504
Score = 358 bits (918), Expect = 2e-97
Identities = 171/192 (89%), Positives = 183/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEGKTSV YE VYSD QARF S+YRFDV+KLEP+VAKPHSPDNRA ARECKDV
Sbjct: 302 DETTFKYLEGKTSVDYEPVYSDAQARFFSDYRFDVSKLEPVVAKPHSPDNRAPARECKDV 361
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAK+FLASG KKVKVPTFLVPATQKVW+DVYSLPVPGSGG
Sbjct: 362 KIDRVYIGSCTGGKTEDFLAAAKLFLASG-KKVKVPTFLVPATQKVWLDVYSLPVPGSGG 420
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASP+CGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 421 KTCSQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQIY 480
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 481 LASPYTAAASAL 492
[11][TOP]
>UniRef100_UPI0001983576 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983576
Length = 508
Score = 357 bits (916), Expect = 4e-97
Identities = 171/192 (89%), Positives = 183/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KTS+PYE VYSD+QARFLSEYRFD++KLEPLVAKPHSPD ALARECKDV
Sbjct: 306 DSTTHKYLEDKTSLPYEPVYSDEQARFLSEYRFDISKLEPLVAKPHSPDKCALARECKDV 365
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVF ASG KKVKVPTFLVPATQKVWMDVYSLPVPG GG
Sbjct: 366 KIDRVYIGSCTGGKTEDFLAAAKVFHASG-KKVKVPTFLVPATQKVWMDVYSLPVPGCGG 424
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPASP+CGAC+GGP+DTYARMNEPQVCVSTTNRNFPGRMGH+E +IY
Sbjct: 425 KTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQVCVSTTNRNFPGRMGHKESQIY 484
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 485 LASPYTAAASAL 496
[12][TOP]
>UniRef100_C4IZQ5 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4IZQ5_MAIZE
Length = 505
Score = 357 bits (915), Expect = 5e-97
Identities = 169/192 (88%), Positives = 183/192 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEG+TSV Y+ VYSD +ARF S+YRFDV+KLEP+VAKPHSPDNRALARECKDV
Sbjct: 303 DETTFKYLEGRTSVDYQPVYSDAEARFFSDYRFDVSKLEPVVAKPHSPDNRALARECKDV 362
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AA KVFLASG KKVKVPTFLVPATQKVWMDVYSLPVPGSGG
Sbjct: 363 KIDRVYIGSCTGGKTEDFLAAVKVFLASG-KKVKVPTFLVPATQKVWMDVYSLPVPGSGG 421
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASP+CGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 422 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQIY 481
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 482 LASPYTAAASAL 493
[13][TOP]
>UniRef100_B6TYJ6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6TYJ6_MAIZE
Length = 492
Score = 357 bits (915), Expect = 5e-97
Identities = 169/191 (88%), Positives = 183/191 (95%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLEG+TSV Y+ VYSD +ARF S+YRFDV+KLEP+VAKPHSPDNRALARECKDV
Sbjct: 303 DETTFKYLEGRTSVDYQPVYSDAEARFFSDYRFDVSKLEPVVAKPHSPDNRALARECKDV 362
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVFLASG KKVKVPTFLVPATQKVWMDVYSLPVPGSGG
Sbjct: 363 KIDRVYIGSCTGGKTEDFLAAAKVFLASG-KKVKVPTFLVPATQKVWMDVYSLPVPGSGG 421
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASP+CGACLGGP+DTYARMNEP VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 422 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNEPTVCVSTTNRNFPGRMGHKEGQIY 481
Query: 542 LASPYTAAASA 574
LASPYTAAASA
Sbjct: 482 LASPYTAAASA 492
[14][TOP]
>UniRef100_Q94AR8 3-isopropylmalate dehydratase n=1 Tax=Arabidopsis thaliana
RepID=LEUC_ARATH
Length = 509
Score = 344 bits (882), Expect = 3e-93
Identities = 162/192 (84%), Positives = 181/192 (94%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T Y+E +TSVP+E VYSD A F+++YRFDV+KLEP+VAKPHSPDNRALARECKDV
Sbjct: 307 DATTLNYVENRTSVPFEPVYSDGNASFVADYRFDVSKLEPVVAKPHSPDNRALARECKDV 366
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAK+F A+G +KVKVPTFLVPATQKVWMDVY+LPVPG+GG
Sbjct: 367 KIDRVYIGSCTGGKTEDFMAAAKLFHAAG-RKVKVPTFLVPATQKVWMDVYALPVPGAGG 425
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQVCVSTTNRNFPGRMGH+EG+IY
Sbjct: 426 KTCAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIY 485
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 486 LASPYTAAASAL 497
[15][TOP]
>UniRef100_C0PRG9 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=C0PRG9_PICSI
Length = 237
Score = 339 bits (870), Expect = 8e-92
Identities = 159/192 (82%), Positives = 178/192 (92%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ YLEGKTS +E++YSD+ AR+L EYRFDV+KLEPLVAKPHSPDNRALAREC+ +
Sbjct: 36 DQTTFDYLEGKTSSSFEALYSDEAARYLQEYRFDVSKLEPLVAKPHSPDNRALARECRHI 95
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAK+ L S G+KVKVPTFLVPATQKVWMD+Y+LPVPG G
Sbjct: 96 KIDRVYIGSCTGGKTEDFMAAAKI-LISAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 154
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASP+CGACLGGP+DTYARMN PQVCVSTTNRNFPGRMGH+EG+IY
Sbjct: 155 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHKEGQIY 214
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 215 LASPYTAAASAL 226
[16][TOP]
>UniRef100_B8LQY6 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQY6_PICSI
Length = 515
Score = 339 bits (870), Expect = 8e-92
Identities = 159/192 (82%), Positives = 178/192 (92%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ YLEGKTS +E++YSD+ AR+L EYRFDV+KLEPLVAKPHSPDNRALAREC+ +
Sbjct: 314 DQTTFDYLEGKTSSSFEALYSDEAARYLQEYRFDVSKLEPLVAKPHSPDNRALARECRHI 373
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAK+ L S G+KVKVPTFLVPATQKVWMD+Y+LPVPG G
Sbjct: 374 KIDRVYIGSCTGGKTEDFMAAAKI-LISAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 432
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC+QIFEEAGCDTPASP+CGACLGGP+DTYARMN PQVCVSTTNRNFPGRMGH+EG+IY
Sbjct: 433 KTCAQIFEEAGCDTPASPNCGACLGGPRDTYARMNVPQVCVSTTNRNFPGRMGHKEGQIY 492
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 493 LASPYTAAASAL 504
[17][TOP]
>UniRef100_B8LQ24 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQ24_PICSI
Length = 516
Score = 339 bits (869), Expect = 1e-91
Identities = 157/192 (81%), Positives = 179/192 (93%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T+ YLEGKTS +E++YSD+ AR+L EYRFDV+KLEPLVAKPHSPDNRALAREC+ +
Sbjct: 315 DQITFDYLEGKTSSSFEALYSDEAARYLQEYRFDVSKLEPLVAKPHSPDNRALARECRHI 374
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDFMAAAK+ + S G+KVKVPTFLVPATQKVWMD+Y+LPVPG G
Sbjct: 375 KIDRVYIGSCTGGKTEDFMAAAKIMI-SAGQKVKVPTFLVPATQKVWMDLYTLPVPGGNG 433
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTCSQIFEEAGCDTPA+P+CGACLGGP+DTYARMN PQVCVSTTN+NFPGRMGH+EG+IY
Sbjct: 434 KTCSQIFEEAGCDTPANPNCGACLGGPRDTYARMNVPQVCVSTTNKNFPGRMGHKEGQIY 493
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 494 LASPYTAAASAL 505
[18][TOP]
>UniRef100_A9TGU1 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9TGU1_PHYPA
Length = 518
Score = 333 bits (853), Expect = 7e-90
Identities = 158/192 (82%), Positives = 176/192 (91%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T KYLEGKTS PY+ SD A FL EYRFDV+KLEPLVAKPHSPDNR LARECKDV
Sbjct: 317 DATTAKYLEGKTSKPYQVFTSDGNASFLQEYRFDVSKLEPLVAKPHSPDNRGLARECKDV 376
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAA++ LA G+KVKVPTFLVPATQKVWMD+YSLPVPG+ G
Sbjct: 377 KIDRVYIGSCTGGKTEDFLAAAEL-LAISGQKVKVPTFLVPATQKVWMDLYSLPVPGTDG 435
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KTC++IF++AGCDTPASPSC ACLGGP+DTYARMN+PQVCVSTTNRNFPGRMGH+EG+IY
Sbjct: 436 KTCAEIFQQAGCDTPASPSCAACLGGPRDTYARMNDPQVCVSTTNRNFPGRMGHKEGQIY 495
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 496 LASPYTAAASAL 507
[19][TOP]
>UniRef100_A7QRJ3 Chromosome chr8 scaffold_150, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QRJ3_VITVI
Length = 424
Score = 302 bits (773), Expect = 1e-80
Identities = 146/166 (87%), Positives = 154/166 (92%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KT VPYE VYSD+QARFLSEYRFDV+KLEPLVAKPHSPDNRALARECKDV
Sbjct: 260 DSTTHKYLEDKTDVPYEPVYSDEQARFLSEYRFDVSKLEPLVAKPHSPDNRALARECKDV 319
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVF AS GKKVKVPTFLVPATQKVWMDVYSLPVPG GG
Sbjct: 320 KIDRVYIGSCTGGKTEDFLAAAKVFHAS-GKKVKVPTFLVPATQKVWMDVYSLPVPGCGG 378
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNR 499
KTCSQIFEEAGCDTPASPSCGACLGGP+DTYARMNEPQ + N+
Sbjct: 379 KTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQASMRLYNK 424
[20][TOP]
>UniRef100_A5AN38 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5AN38_VITVI
Length = 252
Score = 301 bits (772), Expect = 2e-80
Identities = 164/235 (69%), Positives = 172/235 (73%), Gaps = 50/235 (21%)
Frame = +2
Query: 23 LEGKTSVPYE--SVYSDQQARFLSEYRFDVTKLEPLVAK---------------PHSPDN 151
LEGK P+ S+ D RFLSEYRFDV+KLEPLVAK PHSPDN
Sbjct: 8 LEGKRR-PFTKASLRRDSVHRFLSEYRFDVSKLEPLVAKVRDFYMALSEIIFIFPHSPDN 66
Query: 152 RALARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDV 331
RALARECKDVKI+RVYIGSCTGGKTEDF+AAAKVF SG KKVKVPTFLVPATQKVWMDV
Sbjct: 67 RALARECKDVKIDRVYIGSCTGGKTEDFLAAAKVFHVSG-KKVKVPTFLVPATQKVWMDV 125
Query: 332 YSLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQ------------ 475
YSLPVPG GGKTCSQIFEEAGCDTPASPSCGACLGGP+DTYARMNEPQ
Sbjct: 126 YSLPVPGCGGKTCSQIFEEAGCDTPASPSCGACLGGPRDTYARMNEPQATFGCGWIPFFF 185
Query: 476 ---------------------VCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
VCVSTTNRNFPGRMGH+EG+IYLASPYTAAASAL
Sbjct: 186 GHGGCMINYLMILDLLYLHLKVCVSTTNRNFPGRMGHKEGQIYLASPYTAAASAL 240
[21][TOP]
>UniRef100_A8JG03 Isopropylmalate dehydratase, large subunit n=1 Tax=Chlamydomonas
reinhardtii RepID=A8JG03_CHLRE
Length = 487
Score = 296 bits (757), Expect = 1e-78
Identities = 136/192 (70%), Positives = 167/192 (86%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ Y++ +T +E VYSD A ++++Y++DV+KLEPLVA PHSPDNR AREC DV
Sbjct: 286 DQTTFDYVKARTQEAFEPVYSDGAASYIADYKWDVSKLEPLVAAPHSPDNRKTARECSDV 345
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF++AAK+F + ++VKVPT+LVPATQKVW DVY++PVPG G
Sbjct: 346 KIDRVYIGSCTGGKTEDFISAAKLFYRAK-RQVKVPTYLVPATQKVWADVYTMPVPGCDG 404
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KT ++IFEE+GC TPA+PSC ACLGGP+DT+ARMNEP+VCVSTTNRNFPGRMGH+EG+IY
Sbjct: 405 KTAAEIFEESGCITPAAPSCAACLGGPRDTFARMNEPEVCVSTTNRNFPGRMGHKEGQIY 464
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 465 LASPYTAAASAL 476
[22][TOP]
>UniRef100_A7NXJ3 Chromosome chr5 scaffold_2, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7NXJ3_VITVI
Length = 507
Score = 293 bits (750), Expect = 7e-78
Identities = 140/158 (88%), Positives = 150/158 (94%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS T+KYLE KTS+PYE VYSD+QARFLSEYRFD++KLEPLVAKPHSPD ALARECKDV
Sbjct: 323 DSTTHKYLEDKTSLPYEPVYSDEQARFLSEYRFDISKLEPLVAKPHSPDKCALARECKDV 382
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKTEDF+AAAKVF AS GKKVKVPTFLVPATQKVWMDVYSLPVPG GG
Sbjct: 383 KIDRVYIGSCTGGKTEDFLAAAKVFHAS-GKKVKVPTFLVPATQKVWMDVYSLPVPGCGG 441
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQ 475
KTCSQIFEEAGCDTPASP+CGAC+GGP+DTYARMNEPQ
Sbjct: 442 KTCSQIFEEAGCDTPASPTCGACMGGPRDTYARMNEPQ 479
[23][TOP]
>UniRef100_Q111B2 Homoaconitate hydratase family protein n=1 Tax=Trichodesmium
erythraeum IMS101 RepID=Q111B2_TRIEI
Length = 439
Score = 261 bits (668), Expect = 2e-68
Identities = 124/192 (64%), Positives = 156/192 (81%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T++YL G+T P+ES YSD+ A F S+ +DVTKLEP+VAKPHSPDN+ LAR C+DV
Sbjct: 243 DEMTFEYLRGRTDKPFESFYSDKNAEFYSDRSYDVTKLEPVVAKPHSPDNKELARNCQDV 302
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+RVYIGSCTGGKT DF+ AAK+ +VKVPT+LVPATQKV+ D++ + G
Sbjct: 303 KIDRVYIGSCTGGKTSDFLHAAKLI---KDHQVKVPTYLVPATQKVYEDLFIIK---HDG 356
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KT S+IF +AGC PA+PSC ACLGGPKDT+ R+NEP++CVSTTNRNFPGRMG+++ ++Y
Sbjct: 357 KTLSEIFLDAGCIEPAAPSCAACLGGPKDTFGRLNEPEICVSTTNRNFPGRMGNKQAQVY 416
Query: 542 LASPYTAAASAL 577
LASPYTAAASAL
Sbjct: 417 LASPYTAAASAL 428
[24][TOP]
>UniRef100_C0Z3H8 AT4G13430 protein n=1 Tax=Arabidopsis thaliana RepID=C0Z3H8_ARATH
Length = 175
Score = 249 bits (635), Expect = 1e-64
Identities = 117/130 (90%), Positives = 127/130 (97%)
Frame = +2
Query: 188 NRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKT 367
+RVYIGSCTGGKTEDFMAAAK+F A+G +KVKVPTFLVPATQKVWMDVY+LPVPG+GGKT
Sbjct: 35 DRVYIGSCTGGKTEDFMAAAKLFHAAG-RKVKVPTFLVPATQKVWMDVYALPVPGAGGKT 93
Query: 368 CSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLA 547
C+QIFEEAGCDTPASPSCGACLGGP DTYAR+NEPQVCVSTTNRNFPGRMGH+EG+IYLA
Sbjct: 94 CAQIFEEAGCDTPASPSCGACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLA 153
Query: 548 SPYTAAASAL 577
SPYTAAASAL
Sbjct: 154 SPYTAAASAL 163
[25][TOP]
>UniRef100_C4C1N1 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4C1N1_9FUSO
Length = 435
Score = 203 bits (516), Expect = 9e-51
Identities = 99/192 (51%), Positives = 137/192 (71%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y+ KT P+E +YSD+ A + +EY+++ ++EP+VAKP +P N LA+ DV
Sbjct: 236 DEITVEYVTEKTDKPFELIYSDKDADYSAEYKYNANEMEPIVAKPFNPGNTDLAKNLGDV 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K++R YIGSCTGGKT DF+AAAK+ G+KV + TF+VP+T KV + + + G
Sbjct: 296 KLDRAYIGSCTGGKTTDFVAAAKIL---KGRKVAIETFIVPSTVKVEEALSKIII---DG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+TC +IFE+AGC PSC ACLGGP DT+ R + +V +STTNRNFPGRMG + ++Y
Sbjct: 350 ETCMEIFEKAGCKI-GPPSCAACLGGPVDTFGRTHANEVVISTTNRNFPGRMGSMDSQVY 408
Query: 542 LASPYTAAASAL 577
LASPYTAAASA+
Sbjct: 409 LASPYTAAASAV 420
[26][TOP]
>UniRef100_A1BES2 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BES2_CHLPD
Length = 431
Score = 200 bits (508), Expect = 7e-50
Identities = 107/192 (55%), Positives = 127/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D++T Y+ +T PYE SD AR+ S Y ++V +LEP+VA PHSPDNRA R +
Sbjct: 236 DAITEAYVNARTQKPYELFRSDPDARYHSSYTYNVRELEPVVACPHSPDNRATVRSVQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I R YIGSCTGGK DFM AAK+ GKKV VPT +VPAT KV D L + G
Sbjct: 296 AITRSYIGSCTGGKLSDFMMAAKIL---NGKKVSVPTNIVPATVKVAAD---LAIEQYEG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+T QIFE+AGC A PSC ACLGGP DT R + V VSTTNRNFPGRMG ++ +Y
Sbjct: 350 RTLKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKKAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[27][TOP]
>UniRef100_A4SFC8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SFC8_PROVI
Length = 431
Score = 196 bits (499), Expect = 8e-49
Identities = 103/192 (53%), Positives = 128/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +++ KTS PYE SD A + S+ R++ +++EP+VAKPHSPDNRA + K
Sbjct: 236 DEITEAFVKSKTSKPYEIFTSDPGAAYFSKTRYNASEMEPVVAKPHSPDNRATVQSMKGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DF AAK+ GK+V VPT +VPAT KV + L G
Sbjct: 296 KITKSYIGSCTGGKLADFKLAAKIL---SGKRVSVPTNIVPATVKV---AHDLETELYNG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K+ IFE+AGC A PSC ACLGGP DT R + V VSTTNRNFPGRMG ++ E+Y
Sbjct: 350 KSLKSIFEDAGCSI-ALPSCAACLGGPTDTVGRSVDRDVVVSTTNRNFPGRMGSKQAEVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[28][TOP]
>UniRef100_B4SDL0 Homoaconitate hydratase family protein n=1 Tax=Pelodictyon
phaeoclathratiforme BU-1 RepID=B4SDL0_PELPB
Length = 431
Score = 195 bits (496), Expect = 2e-48
Identities = 106/192 (55%), Positives = 127/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS+ Y++ ++ PYE SD AR+ S+YR+DV LEP+VA+PHSPDNRA R +
Sbjct: 236 DSIAENYVKARSQKPYELFQSDPDARYHSKYRYDVRTLEPVVAQPHSPDNRATVRSVQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DFM AAK+ G KV V T +VPAT KV D L G
Sbjct: 296 KITKSYIGSCTGGKLTDFMMAAKIL---KGHKVSVTTNIVPATVKVARD---LECELYDG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
++ QIFE+AGC T A PSC ACLGGP DT R + V VSTTNRNFPGRMG + +Y
Sbjct: 350 QSLKQIFEDAGC-TIALPSCAACLGGPADTVGRSVDNDVVVSTTNRNFPGRMGSKHAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[29][TOP]
>UniRef100_Q3APC5 3-isopropylmalate dehydratase n=1 Tax=Chlorobium chlorochromatii
CaD3 RepID=Q3APC5_CHLCH
Length = 431
Score = 192 bits (489), Expect = 1e-47
Identities = 103/192 (53%), Positives = 126/192 (65%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D++ +Y++ +T PYE SD A++ S YR++V LEP+VA+PHSPDNRA R
Sbjct: 236 DNIAEEYVKARTKKPYEIFQSDPDAKYHSTYRYNVRDLEPVVAQPHSPDNRATVRSVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DFM AAK+ G+KV V T +VPAT V SL G
Sbjct: 296 KITKSYIGSCTGGKLSDFMMAAKIL---KGQKVTVTTTIVPATTLV---ARSLETEQYDG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K+ QIFEEAGC+ A PSC ACLGGP DT R + + VSTTNRNFPGRMG + +Y
Sbjct: 350 KSLKQIFEEAGCNV-ALPSCAACLGGPADTVGRSVDNDLVVSTTNRNFPGRMGSKHAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[30][TOP]
>UniRef100_B3EHN8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium limicola
DSM 245 RepID=B3EHN8_CHLL2
Length = 431
Score = 191 bits (485), Expect = 3e-47
Identities = 104/192 (54%), Positives = 127/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+VT Y++ +S PYE SD A + S YR++ +LEP+VAKPHSPDNRA R +
Sbjct: 236 DAVTEAYVKAHSSKPYEIFQSDPDADYHSVYRYNARELEPVVAKPHSPDNRATVRSMQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DFM AAK+ GK+V VPT +VPAT V +L G
Sbjct: 296 KITKSYIGSCTGGKLTDFMLAAKIL---KGKQVTVPTNIVPATVLV---ARALECETWEG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
T +IFE+AGC A PSC ACLGGP DT R + V VSTTNRNFPGRMG ++ ++Y
Sbjct: 350 VTLKKIFEDAGCSI-ALPSCAACLGGPADTVGRSADQDVVVSTTNRNFPGRMGSKKADVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAV 420
[31][TOP]
>UniRef100_Q3B597 3-isopropylmalate dehydratase n=1 Tax=Chlorobium luteolum DSM 273
RepID=Q3B597_PELLD
Length = 431
Score = 191 bits (484), Expect = 5e-47
Identities = 102/192 (53%), Positives = 126/192 (65%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +++ +T+ YE +SD A++ S YR+D +KLEP+VAKPHSPDNRA R
Sbjct: 236 DEITEAFVKARTTKSYEIFHSDPDAKYHSLYRYDASKLEPVVAKPHSPDNRATVRSVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I + YIGSCTGGK DF AA++ G+KV V T +VPAT +V D L G
Sbjct: 296 PITKSYIGSCTGGKLTDFKMAARIL---NGRKVAVTTNIVPATVQVARD---LEQEMHEG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KT QIF EAGC+ A PSC ACLGGP DT R + + VSTTNRNFPGRMG + E+Y
Sbjct: 350 KTLKQIFMEAGCNI-ALPSCAACLGGPADTVGRSVDRDIVVSTTNRNFPGRMGSKNAEVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[32][TOP]
>UniRef100_C1ZRL8 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Rhodothermus marinus
DSM 4252 RepID=C1ZRL8_RHOMR
Length = 432
Score = 190 bits (482), Expect = 8e-47
Identities = 97/192 (50%), Positives = 127/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+ +T P+E +SD AR+ SEY +DV+KLEP+VAKPH PDNRA E
Sbjct: 236 DEKTIAYVRERTDAPFEIYHSDPDARYHSEYVYDVSKLEPVVAKPHRPDNRATVTEVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K++R YIGSCTGGK EDF+AAA++ G++V++ TF+VPA+ V ++ + G
Sbjct: 296 KLDRAYIGSCTGGKLEDFIAAARIL---KGQEVRIDTFVVPASTYVEQQLHHYKI---DG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ IF AGC SCGACLGGP DT+ R + +V +STTNRNFPGRMG ++ +Y
Sbjct: 350 VSLYDIFVNAGCKI-GHASCGACLGGPPDTFGRTHGTEVVISTTNRNFPGRMGSKQASVY 408
Query: 542 LASPYTAAASAL 577
LASP T AASAL
Sbjct: 409 LASPLTVAASAL 420
[33][TOP]
>UniRef100_UPI00016C35D3 homoaconitate hydratase family protein n=1 Tax=Gemmata
obscuriglobus UQM 2246 RepID=UPI00016C35D3
Length = 435
Score = 188 bits (478), Expect = 2e-46
Identities = 99/194 (51%), Positives = 127/194 (65%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSV--PYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK 175
D VT Y+ + + PY V SD A+F+ E +DV+KLEP++AKPHSPDN+A + K
Sbjct: 237 DQVTLDYVNKRNAGNRPYTVVKSDPGAQFVFEKVYDVSKLEPVIAKPHSPDNKAFVSQVK 296
Query: 176 DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGS 355
K++R YIGSCTGGK DF AAA++ GK VK+ TF+VPAT +V L
Sbjct: 297 GTKLDRAYIGSCTGGKLTDFKAAAQLL---NGKTVKIDTFVVPATTEV---ARGLDTETI 350
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
GG++ IF AG SC ACLGGP DT+ R+N P C+STTNRNFPGRMGH++ +
Sbjct: 351 GGRSLRDIFLSAGAKI-GDASCAACLGGPSDTFGRLNAPISCISTTNRNFPGRMGHKDAQ 409
Query: 536 IYLASPYTAAASAL 577
++LASP T AASAL
Sbjct: 410 VFLASPLTVAASAL 423
[34][TOP]
>UniRef100_B4S6N0 Homoaconitate hydratase family protein n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S6N0_PROA2
Length = 432
Score = 187 bits (476), Expect = 4e-46
Identities = 98/192 (51%), Positives = 128/192 (66%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT Y++ +TS PYE +SD A + S Y ++V +LEP+VA+PHSPDNRA R +
Sbjct: 236 DEVTEAYVKARTSKPYEIFHSDPDAIYHSIYHYNVEELEPVVAQPHSPDNRATVRSVQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+I + YIGSCTGGK DF AAK+ G++V + T +VPAT +V SL G
Sbjct: 296 RITKSYIGSCTGGKLSDFKMAAKIL---NGQQVSIQTNIVPATVEV---AKSLETEQYEG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K+ ++ E+AGC T A PSC ACLGGP DT+ R + + VSTTNRNFPGRMG ++ +Y
Sbjct: 350 KSIRKVLEDAGC-TIAQPSCAACLGGPADTFGRSEDNDLVVSTTNRNFPGRMGSKKAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[35][TOP]
>UniRef100_Q8KER8 3-isopropylmalate dehydratase, large subunit, putative n=1
Tax=Chlorobaculum tepidum RepID=Q8KER8_CHLTE
Length = 431
Score = 187 bits (474), Expect = 7e-46
Identities = 103/192 (53%), Positives = 123/192 (64%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+VT +++ +TS PYE SD A++ S YR++V K+EP+VAKPHSPDNRA
Sbjct: 236 DAVTEAFVKARTSKPYEIFTSDPDAQYHSMYRYNVEKMEPIVAKPHSPDNRATVHSVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I + YIGSCTGGK DF AAK+ GKKV V T +VPAT V L G
Sbjct: 296 PITKSYIGSCTGGKLTDFKLAAKIL---KGKKVAVTTNIVPATVLV---ASQLETEMYDG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+T IFEEAGC+ A PSC ACLGGP DT R + V VSTTNRNFPGRMG + +Y
Sbjct: 350 QTLRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKFASVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[36][TOP]
>UniRef100_B3QM97 Homoaconitate hydratase family protein n=1 Tax=Chlorobaculum parvum
NCIB 8327 RepID=B3QM97_CHLP8
Length = 431
Score = 186 bits (472), Expect = 1e-45
Identities = 104/192 (54%), Positives = 124/192 (64%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+VT +++ +TS PYE SD A++ S YR++V KLEP+VA+PHSPDNRA R
Sbjct: 236 DAVTEAFVKARTSKPYEIFQSDPDAQYHSMYRYNVEKLEPVVAQPHSPDNRATVRSVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I + YIGSCTGGK DF AAK+ GKKV V T +VPAT V L G
Sbjct: 296 PITKSYIGSCTGGKITDFRLAAKIL---KGKKVAVTTNIVPATVLV---ASQLENEMYDG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+T IFEEAGC+ A PSC ACLGGP DT R + V VSTTNRNFPGRMG + +Y
Sbjct: 350 QTLRHIFEEAGCNI-ALPSCAACLGGPSDTVGRSVDNDVVVSTTNRNFPGRMGSKMAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAV 420
[37][TOP]
>UniRef100_Q0YQD5 Homoaconitate hydratase family protein:3-isopropylmalate
dehydratase, prokaryotic n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YQD5_9CHLB
Length = 431
Score = 186 bits (472), Expect = 1e-45
Identities = 101/192 (52%), Positives = 123/192 (64%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DSV Y+ ++ PYE SD A++ S Y ++V +LEP+VA+PHSPDNRA R +
Sbjct: 236 DSVAESYVRARSQKPYEIFRSDPDAKYHSRYHYNVRELEPVVAQPHSPDNRATVRSVQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DF+ AAK+ GKKV V T +VPAT V +L G
Sbjct: 296 KITKSYIGSCTGGKLTDFVMAAKIL---KGKKVSVTTNIVPATVLV---ARALETERFEG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
T QIFE+AGC A PSC ACLGGP DT R + + VSTTNRNFPGRMG + +Y
Sbjct: 350 VTLKQIFEDAGCSI-ALPSCAACLGGPSDTVGRSVDNDLVVSTTNRNFPGRMGSKHAGVY 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAV 420
[38][TOP]
>UniRef100_B3QSN7 Homoaconitate hydratase family protein n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QSN7_CHLT3
Length = 431
Score = 184 bits (468), Expect = 3e-45
Identities = 95/192 (49%), Positives = 124/192 (64%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +++ +TS PYE +SD A++ S Y ++V +LEP+VAKPHSPDNR R
Sbjct: 236 DEITEAFVKARTSAPYEIFHSDPDAKYFSTYHYNVEELEPVVAKPHSPDNRDTVRNVAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K+ + Y+GSCTGGK DF AAKV G+ VKVPTF+VP + V + + G
Sbjct: 296 KLTKCYLGSCTGGKLTDFEFAAKVL---HGQTVKVPTFVVPGSTLVAKQLTEKTI---DG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
T +IFE+AGC A SC ACLGGP DT R ++ +STTNRNFPGRMG ++ E+Y
Sbjct: 350 MTYMEIFEKAGC-IIAESSCAACLGGPADTVGRSSDGDTVISTTNRNFPGRMGSKKSEVY 408
Query: 542 LASPYTAAASAL 577
LASP T AASA+
Sbjct: 409 LASPLTVAASAV 420
[39][TOP]
>UniRef100_B3EKV4 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EKV4_CHLPB
Length = 432
Score = 176 bits (446), Expect = 1e-42
Identities = 98/192 (51%), Positives = 122/192 (63%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS+T Y++ ++ PYE SD A + S +R+ +LEP+VA PHSPDNRA R +
Sbjct: 236 DSITEAYVKERSDKPYEIFTSDPDALYHSIHRYKTEELEPVVAMPHSPDNRATVRSVQGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI + YIGSCTGGK DF+ AAKV G V VPT +VPAT +V SL G
Sbjct: 296 KITKSYIGSCTGGKLIDFVMAAKVL---KGNTVSVPTNIVPATVEV---AQSLTTEEFDG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ I +EAGC T A PSC ACLGGP DT+ R + + VSTTNRNFPGRMG ++ +
Sbjct: 350 QPIITILKEAGC-TIAPPSCAACLGGPSDTFGRSVDNDLVVSTTNRNFPGRMGSKKAGVC 408
Query: 542 LASPYTAAASAL 577
LASP TAAASA+
Sbjct: 409 LASPLTAAASAI 420
[40][TOP]
>UniRef100_B2VKF3 3-isopropylmalate dehydratase large subunit n=1 Tax=Erwinia
tasmaniensis RepID=B2VKF3_ERWT9
Length = 436
Score = 175 bits (443), Expect = 3e-42
Identities = 90/192 (46%), Positives = 122/192 (63%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
+ T YL +T +P+ V D AR+ +VT+++PLVAKPHSPDN K+V
Sbjct: 236 NQATLDYLATRTDIPFSVVEPDADARYSQVLDINVTEMQPLVAKPHSPDNVVAIDTLKNV 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++ YIGSCTGGK DF+AAA+V G+KV VPTF VPAT++V+ + S + G
Sbjct: 296 AISQAYIGSCTGGKLADFIAAARVI---KGRKVVVPTFAVPATKEVFHGLISTDI---DG 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
++ +I +AG + C AC GGP DT+ R+N+P +STTNRNF GRMGH+ IY
Sbjct: 350 QSVYRILCDAGVQLSSESGCAACCGGPADTFGRVNQPISVISTTNRNFVGRMGHKRANIY 409
Query: 542 LASPYTAAASAL 577
LASPY AA+A+
Sbjct: 410 LASPYAVAAAAV 421
[41][TOP]
>UniRef100_B3E0P6 3-isopropylmalate dehydratase large subunit n=1
Tax=Methylacidiphilum infernorum V4 RepID=B3E0P6_METI4
Length = 455
Score = 172 bits (435), Expect = 2e-41
Identities = 87/192 (45%), Positives = 119/192 (61%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D V K L+ T +E V D+ F + Y D++ +EP VA PH+P NR A+E V
Sbjct: 259 DFVRQKVLKNGTKKEFEVVDPDKDQHFFASYFIDLSLVEPTVAAPHNPGNRMKAKELGSV 318
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI+R Y+GSCTGGK DF+A A + + V V TF VP+T +V ++ + + G
Sbjct: 319 KIDRAYLGSCTGGKLSDFIAFASILK---NRTVSVETFAVPSTPEVVDQLHKIEIEG--- 372
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K+ EAG +PSC ACLGGP DT+ R+N+P VC+S+TNRNFPGRMG + ++Y
Sbjct: 373 KSIWDTLREAGVQITENPSCAACLGGPMDTFGRVNKPLVCISSTNRNFPGRMGDKSSQVY 432
Query: 542 LASPYTAAASAL 577
LASP T A+SA+
Sbjct: 433 LASPLTVASSAI 444
[42][TOP]
>UniRef100_B4D0Q5 Aconitate hydratase domain protein n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0Q5_9BACT
Length = 456
Score = 172 bits (435), Expect = 2e-41
Identities = 93/184 (50%), Positives = 114/184 (61%)
Frame = +2
Query: 26 EGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIG 205
E T +E DQ +F+ + FD++KLEP VA P R A+E V ++R YIG
Sbjct: 267 ENGTKSTFEPAEIDQDQKFIYDKVFDLSKLEPTVACHPDPGQRKTAKELAGVSLDRAYIG 326
Query: 206 SCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFE 385
SCTGGKT DF+A A+V GK VK+ TF VPAT KV V L G++ I E
Sbjct: 327 SCTGGKTSDFLAFARVVK---GKSVKIDTFGVPATTKV---VQELKDTQWDGQSVWNILE 380
Query: 386 EAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAA 565
AG + SC ACLGGP DT+ RMN P C+S TNRNFPGRMGH+E +++LASPYT A
Sbjct: 381 SAGVRMTENASCAACLGGPVDTFGRMNTPLKCISATNRNFPGRMGHKESQVFLASPYTVA 440
Query: 566 ASAL 577
ASAL
Sbjct: 441 ASAL 444
[43][TOP]
>UniRef100_A9PBQ8 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9PBQ8_POPTR
Length = 97
Score = 169 bits (429), Expect = 1e-40
Identities = 75/85 (88%), Positives = 84/85 (98%)
Frame = +2
Query: 323 MDVYSLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRN 502
MD+Y+LPVPGSGGKTCSQIFEEAGCDTPA+P+CGAC+GGP+DTYARMN+P VCVSTTNRN
Sbjct: 1 MDLYTLPVPGSGGKTCSQIFEEAGCDTPANPTCGACMGGPRDTYARMNKPVVCVSTTNRN 60
Query: 503 FPGRMGHREGEIYLASPYTAAASAL 577
FPGRMGH+EG+IYLASPYTAAASAL
Sbjct: 61 FPGRMGHKEGQIYLASPYTAAASAL 85
[44][TOP]
>UniRef100_A6DRT0 3-isopropylmalate dehydratase n=1 Tax=Lentisphaera araneosa
HTCC2155 RepID=A6DRT0_9BACT
Length = 433
Score = 168 bits (426), Expect = 2e-40
Identities = 91/192 (47%), Positives = 119/192 (61%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ Y++ +T VPY +D A + Y + ++LEP VA P +PD R E
Sbjct: 236 DAKVEAYVKERTDVPYTLFKADADADYKDVYEINCSELEPTVAIPSAPDKRKGVSEIAGT 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+ R YIGSCTGGKTEDF AAA++ G+KV + TF+VP+T V D+ +L
Sbjct: 296 DLTRAYIGSCTGGKTEDFAAAAEIMY---GQKVAMDTFVVPSTTFVEKDLNTLKFKD--- 349
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
KT +IF EAGC P C ACLGGP+DT+ R + ++ VSTTNRNFPGRMG + ++Y
Sbjct: 350 KTYMEIFLEAGCRI-GPPGCAACLGGPEDTFGRTHAEEIVVSTTNRNFPGRMGSMQAKVY 408
Query: 542 LASPYTAAASAL 577
LASPY AAASAL
Sbjct: 409 LASPYVAAASAL 420
[45][TOP]
>UniRef100_B9XBH0 Aconitate hydratase domain protein n=1 Tax=bacterium Ellin514
RepID=B9XBH0_9BACT
Length = 455
Score = 166 bits (421), Expect = 9e-40
Identities = 91/190 (47%), Positives = 116/190 (61%)
Frame = +2
Query: 8 VTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKI 187
V Y+ T Y+ V D +F+ + D++KLEP VA P R A+E DVK+
Sbjct: 261 VDYRCKLNGTKATYQPVERDANEKFVYDMVVDLSKLEPTVACHPDPGQRKKAKEM-DVKL 319
Query: 188 NRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKT 367
+R YIGSCTGGKT DF+ A+V GK+V + TF VPAT ++ V+ L G KT
Sbjct: 320 DRAYIGSCTGGKTSDFLEFARVLK---GKRVMIDTFGVPATPEI---VHDLQTARWGEKT 373
Query: 368 CSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLA 547
QI +AG + C ACLGGP DT+ RMN P C+S TNRNFPGRMGH+E +++LA
Sbjct: 374 VWQILVDAGVQMTENAGCAACLGGPVDTFGRMNTPMKCISATNRNFPGRMGHKESQVFLA 433
Query: 548 SPYTAAASAL 577
SP T AASAL
Sbjct: 434 SPATVAASAL 443
[46][TOP]
>UniRef100_Q6B920 3-isopropylmalate dehydratase large subunit n=1 Tax=Gracilaria
tenuistipitata var. liui RepID=Q6B920_GRATL
Length = 439
Score = 155 bits (393), Expect = 2e-36
Identities = 79/190 (41%), Positives = 114/190 (60%), Gaps = 1/190 (0%)
Frame = +2
Query: 11 TYKYLEGKTSVP-YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKI 187
T +Y+ ++ + ++ + DQ A + +DVT ++P +AKPHSPDN + KI
Sbjct: 243 TIEYINARSDIKDFDIIVPDQSAHYTKVLEYDVTNIQPQIAKPHSPDNVDSIDNVEGEKI 302
Query: 188 NRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKT 367
+R YIGSCTGGK+ DF AAAK+ KV + TF VPAT++V+ D+ + + +
Sbjct: 303 DRAYIGSCTGGKSSDFYAAAKILK---NHKVSIDTFGVPATREVFYDIINQKIDDI---S 356
Query: 368 CSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLA 547
+I AG PSC AC GGP DT+ R+N +STTNRNF GRMG + +IYL
Sbjct: 357 VYEILVNAGVHMTTEPSCAACCGGPIDTFGRVNNTMSVISTTNRNFSGRMGAKSAQIYLG 416
Query: 548 SPYTAAASAL 577
SPY+ A++A+
Sbjct: 417 SPYSVASTAI 426
[47][TOP]
>UniRef100_B3TAM8 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8G2 RepID=B3TAM8_9ARCH
Length = 423
Score = 150 bits (380), Expect = 5e-35
Identities = 83/192 (43%), Positives = 112/192 (58%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + YL + Y++VY D A++ Y +DVT+LEPLVAKP SP N ++ +E +
Sbjct: 237 DQKVFDYLSERGVTEYDAVYDDDDAQYKKTYEYDVTELEPLVAKPFSPQNVSVVQETTGI 296
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++ YIGSCTG K ED A AK+ GKKVK+ T ++PA ++
Sbjct: 297 ELDKSYIGSCTGAKYEDLEAVAKIL---KGKKVKIRTEILPAAISIYKKATE-------- 345
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 542 LASPYTAAASAL 577
L SP AAASA+
Sbjct: 402 LTSPLVAAASAV 413
[48][TOP]
>UniRef100_B3T9D1 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG6J21 RepID=B3T9D1_9ARCH
Length = 423
Score = 150 bits (380), Expect = 5e-35
Identities = 83/192 (43%), Positives = 112/192 (58%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + YL + Y++VY D A++ Y +DVT+LEPLVAKP SP N ++ +E +
Sbjct: 237 DQKVFDYLSERGVTEYDAVYDDDDAQYKKTYEYDVTELEPLVAKPFSPQNVSVVQETTGI 296
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++ YIGSCTG K ED A AK+ GKKVK+ T ++PA ++
Sbjct: 297 ELDKSYIGSCTGAKYEDLEAVAKIL---KGKKVKIRTEILPAAISIYKKATE-------- 345
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 542 LASPYTAAASAL 577
L SP AAASA+
Sbjct: 402 LTSPLVAAASAV 413
[49][TOP]
>UniRef100_B3T8D2 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG5E24 RepID=B3T8D2_9ARCH
Length = 423
Score = 150 bits (380), Expect = 5e-35
Identities = 83/192 (43%), Positives = 112/192 (58%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + YL + Y++VY D A++ Y +DVT+LEPLVAKP SP N ++ +E +
Sbjct: 237 DQKVFDYLSERGVTEYDAVYDDDDAQYKKTYEYDVTELEPLVAKPFSPQNVSVVQETTGI 296
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++ YIGSCTG K ED A AK+ GKKVK+ T ++PA ++
Sbjct: 297 ELDKSYIGSCTGAKYEDLEAVAKIL---KGKKVKIRTEILPAAISIYKKATE-------- 345
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+QIF +AG P+CGAC G A+ +VCVSTTNRNFPGRMGH E + Y
Sbjct: 346 NGLTQIFIDAGA-VVGPPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVESKTY 401
Query: 542 LASPYTAAASAL 577
L SP AAASA+
Sbjct: 402 LTSPLVAAASAV 413
[50][TOP]
>UniRef100_B3TBB7 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8O8 RepID=B3TBB7_9ARCH
Length = 423
Score = 148 bits (374), Expect = 3e-34
Identities = 81/192 (42%), Positives = 115/192 (59%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + YL + Y++VY D+ A++ Y +DV++LEPLVAKP SP N ++ +E +
Sbjct: 237 DQKVFDYLAERGVTEYDAVYDDEDAQYAKTYEYDVSELEPLVAKPFSPQNVSVVQETTGI 296
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+I++ YIGSCTG K ED +A A++ G+KVKV T +VPA ++ +
Sbjct: 297 EIDKSYIGSCTGAKYEDLVAVARIL---KGRKVKVRTEVVPAAISIYKK--------ASE 345
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+IF +AG +P+CGAC G A+ +VCVSTTNRNFPGRMGH + + Y
Sbjct: 346 NGLDKIFLDAGA-VIGAPTCGACCGAHMGVLAK---DEVCVSTTNRNFPGRMGHVDSKTY 401
Query: 542 LASPYTAAASAL 577
L SP AAASA+
Sbjct: 402 LTSPLVAAASAV 413
[51][TOP]
>UniRef100_C9RAX0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ammonifex
degensii KC4 RepID=C9RAX0_9THEO
Length = 421
Score = 140 bits (352), Expect = 9e-32
Identities = 85/194 (43%), Positives = 111/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YLEG+ PY+ SD AR+ + Y FDV++LEP VA PHSP N E +
Sbjct: 230 DEKTAAYLEGRARRPYKFFQSDPDARYQAVYEFDVSRLEPQVALPHSPANTRPVTEVTHI 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA+V GKKV V ++P TQ+++
Sbjct: 290 TIDQVVIGSCTNGRLEDLRVAAQVL---KGKKVHPYVRLIVIPGTQEIYRQALR------ 340
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 341 --EGLIEIFLEAG-GAVSTPTCGPCLGGHMGVLAK---GERAVATTNRNFVGRMGHPESE 394
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 395 VYLASPAVAAASAV 408
[52][TOP]
>UniRef100_A9A5B7 3-isopropylmalate dehydratase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A5B7_NITMS
Length = 422
Score = 139 bits (350), Expect = 2e-31
Identities = 79/192 (41%), Positives = 112/192 (58%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D YL + + + D A++ + Y ++ +++EPLVAKP SP+N A+ RE V
Sbjct: 236 DQKVVDYLSSRGATNAQVFKGDDDAQYANVYEYEASEMEPLVAKPFSPENIAVVREAPSV 295
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++ YIGSCTG K ED AAAK+ GK VK+ T ++PA+ + +Y +
Sbjct: 296 ELDKSYIGSCTGAKYEDLEAAAKIL---KGKTVKIRTEILPAS----ISIYKRAMENG-- 346
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
IF +AG T P+CGAC G A+ ++C+STTNRNFPGRMGH E E Y
Sbjct: 347 --LLTIFLDAGV-TVGPPTCGACCGAHMGVLAK---NEICISTTNRNFPGRMGHVESETY 400
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 401 LSSPMVAAASAV 412
[53][TOP]
>UniRef100_A4J182 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum reducens MI-1 RepID=A4J182_DESRM
Length = 418
Score = 139 bits (349), Expect = 2e-31
Identities = 79/194 (40%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y+EG+T PY SD A++ Y FDV K+EP VA PH P+N + V
Sbjct: 229 DEITRQYVEGRTKRPYTFYTSDPDAQYSKVYEFDVNKIEPQVAFPHLPENARPVSQAGHV 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++ IGSCT G+ ED AA++ GKKV +V ++P TQ+++
Sbjct: 289 DIDQAVIGSCTNGRMEDLRLAAEIL---KGKKVHQQVRLIVIPGTQEIYRQAMR------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +AG ++P+CG CLGG A+ + C++TTNRNF GRMGH E E
Sbjct: 340 --EGLFEIFLDAGA-VVSTPTCGPCLGGHMGILAK---GERCIATTNRNFVGRMGHAESE 393
Query: 536 IYLASPYTAAASAL 577
+YLA+P AAASA+
Sbjct: 394 VYLANPAVAAASAI 407
[54][TOP]
>UniRef100_C7GFH7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Roseburia
intestinalis L1-82 RepID=C7GFH7_9FIRM
Length = 420
Score = 138 bits (347), Expect = 3e-31
Identities = 81/194 (41%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D++ +Y+E + PY +D+ A + Y D++ L+P VA PH P+N E D+
Sbjct: 231 DNLAKEYMEAHSKRPYVVYEADEDAEYEETYTIDLSTLKPTVAFPHLPENTKTIDEVGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ +D AA + GKKV + ++PATQK+++D
Sbjct: 291 KIDQVVIGSCTNGRMDDLRVAASIL---KGKKVAKGLRVIVIPATQKIYLDAME------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH E E
Sbjct: 342 --EGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EHERCVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 396 IYLASPAVAAASAI 409
[55][TOP]
>UniRef100_A0RXN9 3-isopropylmalate dehydratase large subunit n=1 Tax=Cenarchaeum
symbiosum RepID=A0RXN9_CENSY
Length = 429
Score = 138 bits (347), Expect = 3e-31
Identities = 76/192 (39%), Positives = 112/192 (58%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YL + + + V D A + + ++ +++EPLVAKP+SP+N ++ RE V
Sbjct: 242 DKKTAGYLSSRGATGIKPVIGDDDAEYSEVFEYEGSEMEPLVAKPYSPENVSIVREAPSV 301
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++ YIGSCTG K ED AAA++ G+KV++ T ++PA ++ + G
Sbjct: 302 ELDKAYIGSCTGAKMEDLEAAARIL---KGRKVRIRTEVLPAAISIYRKAVERGLVG--- 355
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
IF +AG T P+CGAC G + + +VC+STTNRNFPGRMG E + Y
Sbjct: 356 -----IFLDAGA-TVGPPTCGACCGAHMGV---LGKGEVCISTTNRNFPGRMGDIESQTY 406
Query: 542 LASPYTAAASAL 577
LASP AAASA+
Sbjct: 407 LASPLVAAASAV 418
[56][TOP]
>UniRef100_C4FRW1 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
17748 RepID=C4FRW1_9FIRM
Length = 419
Score = 136 bits (342), Expect = 1e-30
Identities = 84/195 (43%), Positives = 116/195 (59%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KD 178
D+VT +Y++G+ + P E + D A + D++KL+P+VA PH P N E KD
Sbjct: 230 DAVTEEYIKGRVNRPVEPIAPDADAVYAQTITIDLSKLQPVVAFPHLPSNTHYINEIDKD 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+KI++V IGSCT G+ ED +AAA++F G+KV V ++P +Q DVY +
Sbjct: 290 IKIDQVIIGSCTNGRYEDLVAAAEIFK---GRKVAPFVRCIVIPGSQ----DVYDQAMKD 342
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 343 G----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVDS 394
Query: 533 EIYLASPYTAAASAL 577
E+YLASPY AAASA+
Sbjct: 395 EVYLASPYVAAASAV 409
[57][TOP]
>UniRef100_Q8PZT3 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina mazei RepID=LEUC1_METMA
Length = 391
Score = 136 bits (342), Expect = 1e-30
Identities = 81/192 (42%), Positives = 109/192 (56%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ +L+ + PYE VYSD A +L E+ +D +EP VA PH DN E +
Sbjct: 206 DEKTFDFLKNRAVAPYEPVYSDPDASYLKEFVYDAGDIEPQVACPHQVDNVKPVGEVEGT 265
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V+IG+CT G+ ED AA V GKKV V T ++PA++ +
Sbjct: 266 HVDQVFIGTCTNGRLEDLEVAASVL---KGKKVTVRTIIIPASRSTLLAAIK-------- 314
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+I +AG T A+P CG CLG + + E +VCVST NRNF GRMG ++G IY
Sbjct: 315 NGTMEILLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KDGFIY 369
Query: 542 LASPYTAAASAL 577
LASP TAAASAL
Sbjct: 370 LASPATAAASAL 381
[58][TOP]
>UniRef100_C0V4R3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Veillonella
parvula DSM 2008 RepID=C0V4R3_9FIRM
Length = 419
Score = 135 bits (341), Expect = 2e-30
Identities = 83/195 (42%), Positives = 116/195 (59%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KD 178
D++T +Y++G+ + P E + D A + D++KL+P+VA PH P N E KD
Sbjct: 230 DAITEEYIKGRVNRPVEPIAPDADAVYAQTITIDLSKLQPVVAFPHLPSNTHYINEIDKD 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+KI++V IGSCT G+ ED +AAA++F G+KV V ++P +Q DVY +
Sbjct: 290 IKIDQVIIGSCTNGRYEDLVAAAEIFK---GRKVAPFVRCIVIPGSQ----DVYDQAMKD 342
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
IF +A C ++P+CG CLGG A E + VSTTNRNF GRMGH +
Sbjct: 343 G----LLDIFIQADCAV-STPTCGPCLGGYMGIMA---EGERTVSTTNRNFRGRMGHVDS 394
Query: 533 EIYLASPYTAAASAL 577
E+YLASPY AAASA+
Sbjct: 395 EVYLASPYVAAASAV 409
[59][TOP]
>UniRef100_C1TNL5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dethiosulfovibrio peptidovorans DSM 11002
RepID=C1TNL5_9BACT
Length = 419
Score = 135 bits (340), Expect = 2e-30
Identities = 84/194 (43%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y E + S P+ + Y D+ + DV KL PLVA PHSPDN A D
Sbjct: 229 DETTLAYAEARASRPFTARYPDEGCEYAKRVEIDVEKLTPLVAAPHSPDNVRPASTFGDT 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
+I +V+IGSCT G+ ED AAA V GKKV V ++PA+ +V+
Sbjct: 289 EIQQVFIGSCTNGRLEDMAAAASVL---EGKKVHPSVRCIVIPASYEVYNACLE------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
K + F EAG +P+CG CLGG A E + CVST+NRNF GRMGH + E
Sbjct: 340 --KGYIRTFTEAGA-AVCTPTCGPCLGGHMGILA---EGERCVSTSNRNFVGRMGHPKSE 393
Query: 536 IYLASPYTAAASAL 577
+YLASP TAA SA+
Sbjct: 394 VYLASPVTAAWSAV 407
[60][TOP]
>UniRef100_C0FYL9 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
DSM 16841 RepID=C0FYL9_9FIRM
Length = 436
Score = 134 bits (338), Expect = 4e-30
Identities = 80/194 (41%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + +Y+E + PY +D+ A + +EY D++ L+P V+ PH P+N E DV
Sbjct: 247 DDLAKQYMEEHSKRPYVVYEADEDAEYDAEYTIDLSTLKPTVSFPHLPENTRTIDEVGDV 306
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ +D AA V GKKVK + ++PATQK+++
Sbjct: 307 KIDQVVIGSCTNGRMDDLRIAASVL---KGKKVKKGLRVIVIPATQKIYLQAME------ 357
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH + E
Sbjct: 358 --EGLLRTFIEAGA-VVSTPTCGPCLGGYMGILA---AGERCVSTTNRNFVGRMGHVDSE 411
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 412 VYLASPAVAAASAI 425
[61][TOP]
>UniRef100_C4ZBK5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Eubacterium
rectale ATCC 33656 RepID=C4ZBK5_EUBR3
Length = 420
Score = 134 bits (337), Expect = 5e-30
Identities = 79/194 (40%), Positives = 111/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y++ + P+ +D A + EY D++ L+ V+ PH PDN E DV
Sbjct: 231 DDLTREYMKEHSKRPFTEYEADSDAEYDEEYTIDLSTLKSTVSFPHLPDNTRTIDEVGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ +D AAK+ GKKV + ++PATQK+++
Sbjct: 291 KIDQVVIGSCTNGRMDDLRIAAKIL---EGKKVADGIRVIVIPATQKIYLQAME------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG A E + CVSTTNRNF GRMGH + E
Sbjct: 342 --EGLLKTFIEAGA-IVSTPTCGPCLGGYMGVLA---EGERCVSTTNRNFVGRMGHVDSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[62][TOP]
>UniRef100_C1QEQ6 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
murdochii DSM 12563 RepID=C1QEQ6_9SPIR
Length = 201
Score = 134 bits (337), Expect = 5e-30
Identities = 80/194 (41%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T +YL+ Y +D A + EY D++ +EP VA PH P+N A+E KD+
Sbjct: 15 DNQTIEYLKDIVKRDYTIYKADDDAVYEKEYDIDLSSIEPTVACPHLPENTKDAKELKDI 74
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
K+++V IGSCT G+ D AA + GKK+ V ++PATQKV+ + L
Sbjct: 75 KVDQVVIGSCTNGRLSDMATAANIL---KGKKIAKNVRCIIIPATQKVYKECIKLGY--- 128
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG + +
Sbjct: 129 -----MDIFIDAGC-AVSTPTCGPCLGGYMGILA---HDEVAVTTTNRNFVGRMGDKTSK 179
Query: 536 IYLASPYTAAASAL 577
+YLASP TAA SAL
Sbjct: 180 VYLASPATAAYSAL 193
[63][TOP]
>UniRef100_C0EDN6 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
DSM 5476 RepID=C0EDN6_9CLOT
Length = 421
Score = 134 bits (337), Expect = 5e-30
Identities = 80/194 (41%), Positives = 111/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT Y++ K + PY + D A + + Y D+++++ V+ PH PDN E DV
Sbjct: 231 DEVTIAYMKDKVNRPYTAYAPDPDAEYDAVYDIDLSQIKSTVSFPHLPDNTRTIDEVGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AAK+ GK+V V ++PATQK++++ L
Sbjct: 291 KIDQVVIGSCTNGRLSDIAVAAKIL---EGKQVAKHVRAIVIPATQKIYLEALKLGY--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH E E
Sbjct: 345 -----LETFVKAGC-VVSTPTCGPCLGGHMGILA---AGERAVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPEVAAASAV 409
[64][TOP]
>UniRef100_UPI0001966B48 hypothetical protein SUBVAR_01587 n=1 Tax=Subdoligranulum variabile
DSM 15176 RepID=UPI0001966B48
Length = 419
Score = 134 bits (336), Expect = 7e-30
Identities = 79/194 (40%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + YL+G++ P+ +D A + D+ LEP V+ PH P+N LA+E KD+
Sbjct: 231 DEICEAYLKGRSQRPWVKYEADPDAEYERTVIIDLDTLEPTVSYPHLPENTHLAKEGKDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI+++ IGSCT G+ ED AA ++ GK + V ++PAT V+ +
Sbjct: 291 KIDQIVIGSCTNGRIEDMQAAYEIL---KGKHIAKGVRGIIIPATMAVYKECIL------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ ++ F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + E
Sbjct: 342 --RGYTEAFIDAGC-IVSTPTCGPCLGGYMGILA---AGERCVSTTNRNFVGRMGHVDSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP TAAASAL
Sbjct: 396 VYLASPATAAASAL 409
[65][TOP]
>UniRef100_A5D4W1 3-isopropylmalate dehydratase large subunit n=1 Tax=Pelotomaculum
thermopropionicum SI RepID=A5D4W1_PELTS
Length = 420
Score = 133 bits (335), Expect = 9e-30
Identities = 78/194 (40%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+EG+ PY SD A++ YR+D ++EP VA PH P+N E ++
Sbjct: 231 DETTRVYVEGRCKRPYRFYRSDPDAKYEKIYRYDAAQIEPQVAFPHLPENSRPVSEAGNI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
+I++V IGSCT G+ ED AA+V G+KV V + P T K+++
Sbjct: 291 EIDQVVIGSCTNGRMEDLREAARVL---KGRKVHKNVRLIIFPGTPKIYLQALR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG AR + CV+TTNRNF GRMGH E E
Sbjct: 342 --EGLIETFVEAG-GVVSTPTCGPCLGGHSGILAR---GERCVATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YL++P AAASA+
Sbjct: 396 VYLSNPAVAAASAV 409
[66][TOP]
>UniRef100_Q12TV2 Homoaconitase large subunit n=1 Tax=Methanococcoides burtonii DSM
6242 RepID=Q12TV2_METBU
Length = 413
Score = 133 bits (334), Expect = 1e-29
Identities = 76/192 (39%), Positives = 111/192 (57%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ +LEG+ YE VY+D+ A + +EY D LEP +A PH DN E +
Sbjct: 228 DQKTFDFLEGRAVEGYEPVYADEDAEYCAEYDIDGANLEPQIALPHQVDNVCDVSEIEGK 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K+++V+IG+CT G+ ED AA++ G++V V T ++PA++ + ++
Sbjct: 288 KVDQVFIGTCTNGRLEDLEVAAEIL---KGEQVAVRTIVIPASRSIMLEAVR-------- 336
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
++ +AG T SP CG CLGG + E +VC+ST NRNF GRMG + G IY
Sbjct: 337 NGTAETLLDAGV-TLGSPGCGPCLGGHMGV---IGEGEVCISTANRNFRGRMG-KGGFIY 391
Query: 542 LASPYTAAASAL 577
L+SP TAAASA+
Sbjct: 392 LSSPATAAASAI 403
[67][TOP]
>UniRef100_Q8TVF2 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Methanopyrus
kandleri RepID=LEUC1_METKA
Length = 418
Score = 132 bits (331), Expect = 3e-29
Identities = 81/194 (41%), Positives = 111/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ + V D AR+ +E DV+ LEP VAKP SPDN E + +
Sbjct: 229 DEKTLEYVKKRAGTEGRPVEPDPDARYEAELTLDVSDLEPQVAKPFSPDNVVPVGEVEGI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V+IGSCT G+ ED AA+V G++V V ++PA+++V+ V
Sbjct: 289 AIDQVFIGSCTNGRYEDLKVAAEVL---EGEEVHDDVRLIVIPASREVYHRTLKDGV--- 342
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
++ EAG P+CG CLGG A E + CV+T+NRNFPGRMGHRE E
Sbjct: 343 -----LEVLHEAGA-LICPPNCGPCLGGHMGVLA---EGERCVATSNRNFPGRMGHRESE 393
Query: 536 IYLASPYTAAASAL 577
+YLASP TAAASA+
Sbjct: 394 VYLASPATAAASAI 407
[68][TOP]
>UniRef100_C7H4B6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Faecalibacterium prausnitzii A2-165
RepID=C7H4B6_9FIRM
Length = 419
Score = 131 bits (329), Expect = 4e-29
Identities = 85/197 (43%), Positives = 112/197 (56%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGK---TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC 172
D VT YL G+ T V YE+ D A + D+ KLEP V+ PH P+N A E
Sbjct: 231 DEVTRAYLNGRSQRTPVYYEA---DPDAEYEKTIEIDLDKLEPTVSYPHLPENTHPASEG 287
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPV 346
KD++I++V IGSCT G+ ED AA + GK + V ++PAT V+ +
Sbjct: 288 KDIRIDQVVIGSCTNGRLEDMEAAYNIL---KGKHIAKGVRGIIIPATMAVYKECIL--- 341
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ ++ F +AGC ++P+CG CLGG A E + CVSTTNRNF GRMGH
Sbjct: 342 -----RGWTEAFIDAGC-IVSTPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHV 392
Query: 527 EGEIYLASPYTAAASAL 577
+ E+YLASP TAAASAL
Sbjct: 393 KSEVYLASPATAAASAL 409
[69][TOP]
>UniRef100_B0PBC0 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC0_9FIRM
Length = 419
Score = 130 bits (328), Expect = 6e-29
Identities = 77/194 (39%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT Y++G+ + YE+ D A + D++ + P VA PH P+N E DV
Sbjct: 231 DEVTRAYMQGRVNRTYETFMPDDGAAYARVIEIDLSSIRPTVAFPHLPENTRTVDEAGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+I++V IGSCT G+ D AAA++ GKKV V ++P TQ+++ +
Sbjct: 291 RIDQVVIGSCTNGRIGDLAAAARLM---SGKKVADGVRCIVIPGTQQIYREAIHAGY--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
F +AGC ++P+CG CLGG A E + CV+TTNRNF GRMGH + E
Sbjct: 345 -----IDTFLDAGC-AVSTPTCGPCLGGYMGILA---EGERCVATTNRNFVGRMGHVKSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[70][TOP]
>UniRef100_A6TTR7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Alkaliphilus
metalliredigens QYMF RepID=A6TTR7_ALKMQ
Length = 420
Score = 130 bits (327), Expect = 7e-29
Identities = 79/194 (40%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y+ + PY +D+ A + Y D+++L P VA PH PDN E DV
Sbjct: 231 DELTLEYVRVHSKRPYTVYRADEDAVYEETYEIDLSRLLPTVAFPHIPDNIRTIDEVGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ +D AAKV GK+V V + PATQK+++D
Sbjct: 291 KIDQVVIGSCTNGRIQDLRMAAKVM---EGKQVAKGVRVIVFPATQKIYLDAMK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E E
Sbjct: 342 --EGLLETFIKAGA-VVSTPTCGPCLGGHMGVLAK---GERAIATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[71][TOP]
>UniRef100_A8UWH6 3-isopropylmalate dehydratase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1
RepID=A8UWH6_9AQUI
Length = 432
Score = 130 bits (327), Expect = 7e-29
Identities = 78/196 (39%), Positives = 110/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ + ++ SD A + S Y +D +K+EPLVA P+ P N E +
Sbjct: 230 DDKTIEYVKERAQKEWKVYESDPDAEYHSVYEWDASKIEPLVAWPYLPSNVHPVSESTHI 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLAS--GGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
+++ +IGSCT G+ ED AAKVF ++ GKKV V ++PA++ V+M
Sbjct: 290 NVDQAFIGSCTNGRIEDLRIAAKVFESALKQGKKVHPYVRCIVIPASKNVYMQAMK---- 345
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ IF EAGC S +CG CLGG A E + C+ST+NRNFPGRMGH +
Sbjct: 346 ----EGLIDIFMEAGCAVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGRMGHPK 397
Query: 530 GEIYLASPYTAAASAL 577
E YLA+P AASA+
Sbjct: 398 SESYLANPAVVAASAV 413
[72][TOP]
>UniRef100_O67078 3-isopropylmalate dehydratase large subunit n=1 Tax=Aquifex
aeolicus RepID=LEUC_AQUAE
Length = 432
Score = 130 bits (327), Expect = 7e-29
Identities = 78/196 (39%), Positives = 110/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ + P++ SD A + S Y +D +++EPLVA P+ P N E +
Sbjct: 230 DEKTIEYVKQRAKRPWKVYQSDPDAEYHSVYEWDASQIEPLVAWPYLPSNVHPVSESTHI 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLAS--GGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
I++ +IGSCT G+ ED AAKVF A+ GKKV V ++PA++ ++
Sbjct: 290 TIDQAFIGSCTNGRIEDLRVAAKVFEAALKQGKKVHPYVRCIVIPASKAIYKQALK---- 345
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ IF EAGC S +CG CLGG A E + C+ST+NRNFPGRMGH +
Sbjct: 346 ----EGLIDIFMEAGCVVSTS-TCGPCLGGHMGVLA---EGERCISTSNRNFPGRMGHPK 397
Query: 530 GEIYLASPYTAAASAL 577
E YLA+P AASA+
Sbjct: 398 SESYLANPAVVAASAI 413
[73][TOP]
>UniRef100_C0R088 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
hyodysenteriae WA1 RepID=C0R088_BRAHW
Length = 415
Score = 130 bits (326), Expect = 1e-28
Identities = 79/194 (40%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ Y +D A + EY D++ +EP VA PH P+N A+E K++
Sbjct: 229 DDQTIEYLKDIVKRDYTVFKADDDAVYDKEYDIDLSLIEPTVACPHLPENTKEAKELKNI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
K+++V IGSCT G+ D AA + GKKV V ++PATQKV+ + L
Sbjct: 289 KVDQVVIGSCTNGRLSDMATAANIL---KGKKVAKGVRCIVIPATQKVYKECIKLGY--- 342
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
IF +AGC ++P+CG CLGG A +V V+TTNRNF GRMG + +
Sbjct: 343 -----MDIFIDAGC-AVSTPTCGPCLGGYMGILA---HDEVAVTTTNRNFVGRMGDKTSK 393
Query: 536 IYLASPYTAAASAL 577
+YLASP TAA SA+
Sbjct: 394 VYLASPATAAYSAI 407
[74][TOP]
>UniRef100_B5YEF5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
thermophilum H-6-12 RepID=B5YEF5_DICT6
Length = 424
Score = 130 bits (326), Expect = 1e-28
Identities = 80/196 (40%), Positives = 111/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARECKD 178
D +T Y+ + ++ SD+ A++ Y +DV+ LEP+VA PH P N + ++ KD
Sbjct: 231 DEITLDYVRNRAKRDFKIYKSDEDAQYKEVYEWDVSDLEPIVAFPHLPSNIKKISEISKD 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+ I++VYIGSCT G+ ED AAK+ G KV V + PAT ++M
Sbjct: 291 IYIDQVYIGSCTNGRIEDLRIAAKILK---GHKVHKDVRLIITPATPNIYMQALK----- 342
Query: 353 SGGKTCSQIFEEAGCD-TPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ +IF EAG TP PSCG CLGG A E + V+TTNRNF GRMGH +
Sbjct: 343 ---EGLIEIFLEAGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPK 394
Query: 530 GEIYLASPYTAAASAL 577
E+YL++P AAASA+
Sbjct: 395 SEVYLSNPAVAAASAI 410
[75][TOP]
>UniRef100_A8S7H1 Putative uncharacterized protein n=1 Tax=Faecalibacterium
prausnitzii M21/2 RepID=A8S7H1_9FIRM
Length = 419
Score = 130 bits (326), Expect = 1e-28
Identities = 81/194 (41%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL G++ P +D A + D++ LEP V+ PH P+N +A E KD+
Sbjct: 231 DEVTKAYLAGRSQRPPVFYEADPDAVYEKTIEIDLSALEPTVSYPHLPENTHVASEGKDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA + GK + V ++PAT V+ +
Sbjct: 291 KIDQVVIGSCTNGRLEDMEAAYNIL---KGKHIAKGVRGIIIPATMAVYKECIL------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + E
Sbjct: 342 --RGWTTAFIDAGC-IVSTPTCGPCLGGYMGILA---AGERCVSTTNRNFVGRMGHVDSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP TAAASAL
Sbjct: 396 VYLASPATAAASAL 409
[76][TOP]
>UniRef100_UPI00016C08CB 3-isopropylmalate dehydratase, large subunit n=1 Tax=Epulopiscium
sp. 'N.t. morphotype B' RepID=UPI00016C08CB
Length = 421
Score = 129 bits (324), Expect = 2e-28
Identities = 78/194 (40%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +YL+G+T Y SD A + D++K+ P V+ PHSPDN E ++
Sbjct: 231 DFITREYLKGRTDREYIVYTSDADAIYDEVITIDLSKVRPTVSCPHSPDNTXTLDELPEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED A+ + GKKV V + P TQ++++D + + +
Sbjct: 291 KIDQVVIGSCTNGRLEDLRMASDIL---KGKKVAKGVRAIVFPGTQQIYLDALAEGIVTN 347
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+AGC ++P+CG CLGG A+ + VSTTNRNF GRMGH E E
Sbjct: 348 --------LVKAGC-VMSTPTCGPCLGGHMGILAK---GEKAVSTTNRNFVGRMGHIESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[77][TOP]
>UniRef100_A3DHI4 3-isopropylmalate dehydratase large subunit n=3 Tax=Clostridium
thermocellum RepID=LEUC_CLOTH
Length = 419
Score = 129 bits (324), Expect = 2e-28
Identities = 76/194 (39%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ ++ Y+ +D+ A +++ Y D+++++P VA PH P N ++
Sbjct: 231 DEKTIEYVKEHSTRQYKVYKADEDAEYVATYEIDLSQVKPTVAFPHLPSNTRTIDNVGNI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA+V G+KV V ++PATQK+W +
Sbjct: 291 KIDQVVIGSCTNGRIEDLRVAAEVL---KGRKVHKDVRCIIIPATQKIWKQAMN------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 342 --EGLFDIFIDAGA-AVSTPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 396 IYLASPAVAAASAV 409
[78][TOP]
>UniRef100_B9L0Y1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermomicrobium roseum DSM 5159 RepID=B9L0Y1_THERP
Length = 422
Score = 129 bits (323), Expect = 2e-28
Identities = 83/194 (42%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T ++L T+ PYE V SD AR+ FDV+ L PLVA PH P N A E +D+
Sbjct: 233 DDKTREWLAKVTTEPYEPVDSDPDARYAQIIEFDVSNLRPLVALPHLPSNVRPADEVRDL 292
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D AA++ G++V +V ++P +Q+V +
Sbjct: 293 PIDQVVIGSCTNGRLSDLRIAAEIL---KGRQVHPRVRCIVIPGSQEV--------AKQA 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGHRE E
Sbjct: 342 TREGLVDIFLEAGAVFSVS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHRESE 397
Query: 536 IYLASPYTAAASAL 577
+ LASP AAASA+
Sbjct: 398 VILASPAVAAASAV 411
[79][TOP]
>UniRef100_Q3Z9A7 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides
ethenogenes 195 RepID=Q3Z9A7_DEHE1
Length = 417
Score = 128 bits (322), Expect = 3e-28
Identities = 77/193 (39%), Positives = 110/193 (56%), Gaps = 1/193 (0%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD 178
D T +YL Y+ + +D+ A + D T LEP+VAKPH+ DN A ARE K
Sbjct: 227 DRQTLEYLRSVGREADYQPLAADEDAVYERVIEIDATALEPMVAKPHTVDNTATARELKG 286
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 358
K+++V+IG+CTGG+ +D AA +F + + + PA+QKV+++ L
Sbjct: 287 TKLDQVFIGTCTGGRLDDLAVAAAIF-KNRRHHPQTRLIVTPASQKVYLEAIRLGY---- 341
Query: 359 GKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEI 538
+I +AG + P CGACLG + + + +VC+ST NRNF GRMG+ EG I
Sbjct: 342 ----IEILVQAGANV-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFI 393
Query: 539 YLASPYTAAASAL 577
YLAS TAAASA+
Sbjct: 394 YLASAATAAASAI 406
[80][TOP]
>UniRef100_B8E2X0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
turgidum DSM 6724 RepID=B8E2X0_DICTD
Length = 424
Score = 128 bits (322), Expect = 3e-28
Identities = 81/196 (41%), Positives = 110/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARECKD 178
D +T +Y+ + ++ SD+ A + Y +DVT LEP+VA PH P N + ++ KD
Sbjct: 231 DEITLEYVRNRAKRNFKVYKSDEDAHYKEIYEWDVTNLEPIVAFPHLPSNIKKISDIGKD 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+ I++VYIGSCT G+ ED AAK+ G KV V + PAT V+M
Sbjct: 291 IYIDQVYIGSCTNGRIEDLRLAAKILK---GHKVHKDVRLIVTPATPNVYMQALK----- 342
Query: 353 SGGKTCSQIFEEAGCD-TPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ +IF E G TP PSCG CLGG A E + V+TTNRNF GRMGH +
Sbjct: 343 ---EGLIEIFLEVGASITP--PSCGPCLGGHLGVLA---EGEKAVATTNRNFVGRMGHPK 394
Query: 530 GEIYLASPYTAAASAL 577
E+YL++P AAASA+
Sbjct: 395 SEVYLSNPAVAAASAI 410
[81][TOP]
>UniRef100_B1I1Y2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Candidatus
Desulforudis audaxviator MP104C RepID=B1I1Y2_DESAP
Length = 420
Score = 128 bits (322), Expect = 3e-28
Identities = 78/192 (40%), Positives = 107/192 (55%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++G+T P+E SD A + +DV+K+EP VA PHSPDN E V
Sbjct: 231 DIRTLEYVQGRTIRPFELFASDPDAVYARTITYDVSKIEPQVAFPHSPDNTRPVTEAGRV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+I++V IGSCT G+ ED AA+V L V ++P TQ+++
Sbjct: 291 EIDQVVIGSCTNGRMEDLRLAARV-LERRRVHAGVRLIVIPGTQEIYRQAME-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ IF +AG ++P+CG CLGG AR + V+TTNRNF GRMGH E E+Y
Sbjct: 342 EGLLAIFIQAGA-AVSTPTCGPCLGGHMGVLAR---GERAVATTNRNFVGRMGHPESEVY 397
Query: 542 LASPYTAAASAL 577
L +P AAASA+
Sbjct: 398 LTNPAVAAASAV 409
[82][TOP]
>UniRef100_C6LJ75 3-isopropylmalate dehydratase, large subunit n=1 Tax=Bryantella
formatexigens DSM 14469 RepID=C6LJ75_9FIRM
Length = 422
Score = 128 bits (322), Expect = 3e-28
Identities = 79/195 (40%), Positives = 111/195 (56%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KD 178
D + Y++ + PY+ +D+ A + EY D++ L+P VA PH P+N E +D
Sbjct: 231 DDLAIAYMKEHSQRPYKIYEADEDAVYDEEYTIDLSALKPTVAFPHLPENTKTIDEITED 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
V I++ IGSCT G+ +D AAK+ G+KVK V ++PATQKV++
Sbjct: 291 VVIDQAVIGSCTNGRIDDLRCAAKIL---EGRKVKKGVRCIVIPATQKVYLQAME----- 342
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ + F EAG ++P+CG CLGG A E + C+STTNRNF GRMGH
Sbjct: 343 ---EGLLKTFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVNS 395
Query: 533 EIYLASPYTAAASAL 577
E+YLASP AAASA+
Sbjct: 396 EVYLASPAVAAASAV 410
[83][TOP]
>UniRef100_C4G1B4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
49176 RepID=C4G1B4_ABIDE
Length = 421
Score = 128 bits (322), Expect = 3e-28
Identities = 78/194 (40%), Positives = 111/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++ ++ PY+ +D+ A + ++++LEP VA PH P+N E D+
Sbjct: 231 DELTLNYIKEHSTKPYKVYEADEDAVYDEVIEINLSELEPTVAFPHLPENTRTIGETGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AA+V GKKV + ++PATQ+V++ S
Sbjct: 291 KIDQVVIGSCTNGRISDIRVAAEVM---KGKKVAPGIRVIVIPATQEVYLT--------S 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F +AGC ++P+CG CLGG A + VSTTNRNF GRMGH E E
Sbjct: 340 LKEGLITTFVQAGC-IVSTPTCGPCLGGHMGVLA---AGERAVSTTNRNFVGRMGHTESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[84][TOP]
>UniRef100_C7II84 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7II84_9CLOT
Length = 419
Score = 128 bits (321), Expect = 4e-28
Identities = 75/194 (38%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ + Y +D+ A++ Y D+ +++P VA PH P+N + D+
Sbjct: 231 DEKTVEYVKEHSIRSYTVYKADEDAQYSEVYEIDLAEIKPTVAFPHLPENARTIDKVGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA++ G+KV V ++PATQK+W +
Sbjct: 291 KIDQVVIGSCTNGRIEDMRIAAQIL---KGQKVSDNVRCIIIPATQKIWKQAMN------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 342 --EGLFDIFIDAGA-AVSTPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[85][TOP]
>UniRef100_Q46B45 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosarcina
barkeri str. Fusaro RepID=Q46B45_METBF
Length = 413
Score = 128 bits (321), Expect = 4e-28
Identities = 77/192 (40%), Positives = 108/192 (56%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ +L+ + + PY+ VY+DQ A ++ E + +EP VA PH DN E +
Sbjct: 228 DEKTFAFLKNRAAAPYDPVYADQDAVYVKEPVYSAEDIEPQVACPHQVDNVKPVGEVEGT 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++V+IG+CT G+ ED AA + GKKV V T ++PA++ +
Sbjct: 288 HIDQVFIGTCTNGRLEDLEVAAAIL---KGKKVAVRTIVIPASRTTLLAAIE-------- 336
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+I +AG T A+P CG CLG + + E +VC+ST NRNF GRMG + G IY
Sbjct: 337 NGTMEILLKAGI-TLATPGCGPCLGAHQGV---LGEGEVCLSTANRNFKGRMG-KSGFIY 391
Query: 542 LASPYTAAASAL 577
LASP TAAASAL
Sbjct: 392 LASPATAAASAL 403
[86][TOP]
>UniRef100_B8CX22 3-isopropylmalate dehydratase large subunit n=1 Tax=Halothermothrix
orenii H 168 RepID=LEUC_HALOH
Length = 420
Score = 128 bits (321), Expect = 4e-28
Identities = 76/192 (39%), Positives = 103/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+KYLE + Y YSD A + +DV+ +EP VA PH P+N E D+
Sbjct: 231 DEKTFKYLENRAQRDYTPCYSDDDAEYEKVIEYDVSDIEPQVAFPHLPENTRPISEEGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++ IGSCT G+ ED AA + L V ++P TQ ++
Sbjct: 291 KIDQAVIGSCTNGRMEDLRIAAGI-LKEKQVHHDVRCIVIPGTQDIYKQALK-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +IF EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E E+Y
Sbjct: 342 EGLIEIFIEAGA-AVSTPTCGPCLGGHMGILAR---GEKAIATTNRNFVGRMGHPESEVY 397
Query: 542 LASPYTAAASAL 577
LA+P AAASA+
Sbjct: 398 LANPAVAAASAI 409
[87][TOP]
>UniRef100_Q8TLF1 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina acetivorans RepID=LEUC1_METAC
Length = 424
Score = 128 bits (321), Expect = 4e-28
Identities = 77/192 (40%), Positives = 108/192 (56%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+++L+ + + YE VY+D A +L E+ +D +EP VA PH DN E +
Sbjct: 239 DEKTFEFLKNRAAATYEPVYADPDAVYLEEFTYDADDIEPQVACPHQVDNVKPVGEVEGT 298
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V+IG+CT G+ ED AA V GK+V V T ++PA++ +
Sbjct: 299 HVDQVFIGTCTNGRLEDLEVAAAVL---KGKQVAVRTIVIPASRTTLLAAIE-------- 347
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +AG T A+P CG CLG + + E +VCVST NRNF GRMG + G IY
Sbjct: 348 NGTMETLLKAGV-TLATPGCGPCLGAHQGV---LGEGEVCVSTANRNFKGRMG-KGGFIY 402
Query: 542 LASPYTAAASAL 577
LASP TAAASAL
Sbjct: 403 LASPATAAASAL 414
[88][TOP]
>UniRef100_C9L6F6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Blautia
hansenii DSM 20583 RepID=C9L6F6_RUMHA
Length = 425
Score = 127 bits (320), Expect = 5e-28
Identities = 79/195 (40%), Positives = 110/195 (56%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T +Y++ + PY+ D+ A + EY D++KL P VA PH P N E +D
Sbjct: 234 DEKTEEYMKEHSKRPYKRYEPDEDAVYDEEYTIDLSKLRPTVAFPHLPSNTKTIDEIQDD 293
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
V I + IGSCT G+ +D AA++ +KVK V ++PATQK+++
Sbjct: 294 VIIQQSVIGSCTNGRIDDLRCAAQILK---NRKVKKGVRCIIIPATQKIYLQALE----- 345
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH +
Sbjct: 346 ---EGLLKIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVKS 398
Query: 533 EIYLASPYTAAASAL 577
E+YLASP AAASA+
Sbjct: 399 EVYLASPAVAAASAI 413
[89][TOP]
>UniRef100_B4U7U5 3-isopropylmalate dehydratase large subunit n=1
Tax=Hydrogenobaculum sp. Y04AAS1 RepID=LEUC_HYDS0
Length = 424
Score = 127 bits (319), Expect = 6e-28
Identities = 74/194 (38%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+E + PY+ SD+ A ++ Y +D + +EP+VA P+ P N E +
Sbjct: 230 DEKTIEYVEKRAKKPYKIYQSDKDAHYVEVYEWDASSIEPMVAWPYLPSNVHPVSESTHI 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPT--FLVPATQKVWMDVYSLPVPGS 355
I++ +IGSCT G+ ED AA + GKKV T ++PA++ V++
Sbjct: 290 TIDQAFIGSCTNGRIEDLRIAASIL---KGKKVHPYTRCVVIPASKNVYLQALH------ 340
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF EAGC S +CG CLGG A+ + C+ST+NRNFPGRMGH + E
Sbjct: 341 --EGLVDIFIEAGCAVSTS-TCGPCLGGHMGILAK---GERCISTSNRNFPGRMGHPQSE 394
Query: 536 IYLASPYTAAASAL 577
YLA+P AASA+
Sbjct: 395 AYLANPAVVAASAV 408
[90][TOP]
>UniRef100_B0TCR2 3-isopropylmalate dehydratase large subunit n=1 Tax=Heliobacterium
modesticaldum Ice1 RepID=LEUC_HELMI
Length = 420
Score = 127 bits (318), Expect = 8e-28
Identities = 77/194 (39%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+E + + PY+ SD A++ ++DV KLEP+VA PH P+N E V
Sbjct: 231 DKKTIAYVEERATRPYKVYTSDPDAKYARVIKYDVEKLEPVVAFPHLPENTRPVSEAGHV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
+I++V IGSCT G+ ED AAK+ GKKV V + P TQ ++
Sbjct: 291 EIDQVVIGSCTNGRIEDLRMAAKIL---QGKKVHKNVRCIIFPGTQAIYKQAIK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E E
Sbjct: 342 --EGLIDIFIDAGA-AVSTPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YL P AAASA+
Sbjct: 396 VYLCGPNVAAASAI 409
[91][TOP]
>UniRef100_Q2RG98 3-isopropylmalate dehydratase large subunit n=1 Tax=Moorella
thermoacetica ATCC 39073 RepID=LEUC_MOOTA
Length = 421
Score = 126 bits (317), Expect = 1e-27
Identities = 75/194 (38%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+ G+ Y SD AR+ E D +K+EP VA PH P+N +E ++
Sbjct: 231 DEKTVEYIRGRLQRDYRIYQSDPDARYNQEIDIDASKIEPQVALPHLPENARSVKEIGEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA++ G+KV +V ++P TQ+++ +
Sbjct: 291 KIDQVVIGSCTNGRLEDLRVAAQIL---KGQKVHPEVRLIVIPGTQQIYAAALA------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH E E
Sbjct: 342 --EGLIATFIEAGA-AVSTPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLA P AAASA+
Sbjct: 396 VYLAGPAVAAASAV 409
[92][TOP]
>UniRef100_C6PQI2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
carboxidivorans P7 RepID=C6PQI2_9CLOT
Length = 421
Score = 126 bits (316), Expect = 1e-27
Identities = 74/192 (38%), Positives = 108/192 (56%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ ++ Y +D+ A + D++ + P VA PH P+N E +V
Sbjct: 231 DDKTIEYVKEHSNREYTVYTADEDAEYSKVIEIDLSSIRPTVAFPHLPENTRTIDEVGEV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++ IGSCT G+ ED AAAKVF + K +V + PATQK++++
Sbjct: 291 FIDQAVIGSCTNGRIEDLRAAAKVFKGNKVNK-RVRAIIFPATQKIYLEALR-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +IF EAG ++P+CG CLGG A+ + ++TTNRNF GRMGH E E+Y
Sbjct: 342 EGLLEIFIEAGA-VVSTPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGHPESEVY 397
Query: 542 LASPYTAAASAL 577
LASP AAASA+
Sbjct: 398 LASPAVAAASAI 409
[93][TOP]
>UniRef100_B5YKE0 3-isopropylmalate dehydratase large subunit n=1
Tax=Thermodesulfovibrio yellowstonii DSM 11347
RepID=LEUC_THEYD
Length = 421
Score = 126 bits (316), Expect = 1e-27
Identities = 74/194 (38%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y++ + PY+ SDQ A++ +D +++ P+VA PH P N A E +
Sbjct: 231 DKITEEYVKLRAKRPYKIYNSDQDAKYFEIKEYDCSRIPPVVACPHLPSNVKPANELSHI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA V G+KV +V ++PATQK++M
Sbjct: 291 KIDQVVIGSCTNGRLEDLREAAMVL---KGRKVHPEVRMIIIPATQKIYMQALK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +A + P+CG CLGG A+ + ++TTNRNF GRMGH E E
Sbjct: 342 --EGLIEIFIDAQA-VVSPPTCGPCLGGHMGILAK---GERAIATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YL++P AAAS +
Sbjct: 396 VYLSNPAVAAASGV 409
[94][TOP]
>UniRef100_Q3AEQ4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Carboxydothermus hydrogenoformans Z-2901
RepID=Q3AEQ4_CARHZ
Length = 421
Score = 125 bits (315), Expect = 2e-27
Identities = 76/194 (39%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y++G+ ++ SD AR+ + Y +V ++EP VA PH P+N +E
Sbjct: 232 DELTLEYVKGRAKREFKVFASDPDARYEAVYEINVEEIEPQVALPHLPENAVPVKEVSGK 291
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA + GKKVK V ++P +Q V+
Sbjct: 292 DIDQVVIGSCTNGRIEDLRVAAAIL---KGKKVKDYVRCIIIPGSQSVYRQALK------ 342
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF EAG ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 343 --EGLIDIFLEAGA-AVSTPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHVESE 396
Query: 536 IYLASPYTAAASAL 577
+YLA P AAASA+
Sbjct: 397 VYLAGPAVAAASAI 410
[95][TOP]
>UniRef100_C0QS35 3-isopropylmalate dehydratase, large subunit n=1 Tax=Persephonella
marina EX-H1 RepID=C0QS35_PERMH
Length = 428
Score = 125 bits (315), Expect = 2e-27
Identities = 75/194 (38%), Positives = 105/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D ++L+ KT P + +D A++ EY FD +K+EP+VA P+ P N E
Sbjct: 231 DEKVLEWLKDKTDRPLRMLKADPDAKYCCEYEFDASKIEPVVAAPNLPSNVKPVTEVAGK 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
IN+V+IGSCT G+ D AA + G+KV V ++PA+ +++
Sbjct: 291 PINQVFIGSCTNGRMSDLRIAAHIL---KGRKVHPDVRCIVIPASDRIYKQALH------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +I +AGC S +CG CLGG A E +VCVST+NRNF GRMGH E
Sbjct: 342 --EGILEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCVSTSNRNFTGRMGHPNSE 395
Query: 536 IYLASPYTAAASAL 577
+YLA P AAASA+
Sbjct: 396 VYLAGPAVAAASAV 409
[96][TOP]
>UniRef100_C4CHB6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Sphaerobacter
thermophilus DSM 20745 RepID=C4CHB6_9CHLR
Length = 418
Score = 125 bits (315), Expect = 2e-27
Identities = 82/194 (42%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T ++L T PYE V SD A +L FDV+ L+P+VA PH P N A E D+
Sbjct: 229 DDKTREWLARVTDRPYEPVESDPDAEYLKVIEFDVSNLKPVVALPHLPSNVYPADEVGDM 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D AK+ G++V V ++P +Q+V +
Sbjct: 289 PIHQVVIGSCTNGRISDLREVAKIL---KGRQVHPNVRCIVIPGSQEV--------AKQA 337
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + IF EAG S +CG CLGG A+ + CVSTTNRNF GRMGHRE E
Sbjct: 338 TREGLADIFLEAGAIFSTS-TCGPCLGGYMGVLAK---GERCVSTTNRNFRGRMGHREAE 393
Query: 536 IYLASPYTAAASAL 577
I LA P AAASA+
Sbjct: 394 IILAGPQVAAASAV 407
[97][TOP]
>UniRef100_A8CU07 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
VS RepID=A8CU07_9CHLR
Length = 417
Score = 125 bits (315), Expect = 2e-27
Identities = 76/193 (39%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD 178
D T +YL Y+ + +D+ A + D T LEP V+KPH+ DN A ARE K
Sbjct: 227 DRQTLEYLRSVGREADYQPLAADENAVYERVIEIDATALEPTVSKPHTVDNTATARELKG 286
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 358
K+++V+IG+CTGG+ +D AA +F + + + PA+QKV+++ L
Sbjct: 287 TKLDQVFIGTCTGGRLDDLAVAAAIF-KNRRHHPQTRLIVTPASQKVYLEAIRLGY---- 341
Query: 359 GKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEI 538
+I +AG + P CGACLG + + + +VC+ST NRNF GRMG+ EG I
Sbjct: 342 ----IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFI 393
Query: 539 YLASPYTAAASAL 577
YLAS TAAASA+
Sbjct: 394 YLASAATAAASAI 406
[98][TOP]
>UniRef100_B9E370 Putative uncharacterized protein n=1 Tax=Clostridium kluyveri NBRC
12016 RepID=B9E370_CLOK1
Length = 426
Score = 125 bits (313), Expect = 3e-27
Identities = 75/194 (38%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ ++ Y +D+ A ++ D++K+ P VA PH P+N E ++
Sbjct: 237 DEKTIEYVKEHSNRSYTVYEADEDAEYVKTIEIDLSKIPPTVAFPHIPENTRTIDEVGEI 296
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AAKV G+KV V T + PATQ +++
Sbjct: 297 KIDQVVIGSCTNGRIGDLRVAAKVL---KGRKVNSNVRTIIFPATQSIYLQAMK------ 347
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 348 --EGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGHVESE 401
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 402 VYLASPAVAAASAV 415
[99][TOP]
>UniRef100_A5FS15 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. BAV1 RepID=A5FS15_DEHSB
Length = 431
Score = 125 bits (313), Expect = 3e-27
Identities = 74/193 (38%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD 178
D T +YL Y+ + +D A + D T LEP ++KPH+ DN A ARE K
Sbjct: 241 DRQTLEYLRSVGREADYQPLAADADAVYERVIEIDATALEPTISKPHTVDNTATARELKG 300
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 358
K+++V+IG+CTGG+ +D AA +F + + + + PA+QK++++ L
Sbjct: 301 TKLDQVFIGTCTGGRLDDLAVAAAIF-KNRKRHPQTRLIVTPASQKIYLEAIRLGY---- 355
Query: 359 GKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEI 538
+I +AG + P CGACLG + + + +VC+ST NRNF GRMG+ EG I
Sbjct: 356 ----IEILVQAGANI-MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFI 407
Query: 539 YLASPYTAAASAL 577
YLAS TAAASA+
Sbjct: 408 YLASAATAAASAI 420
[100][TOP]
>UniRef100_A5ZAM9 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
ATCC 27560 RepID=A5ZAM9_9FIRM
Length = 421
Score = 125 bits (313), Expect = 3e-27
Identities = 76/194 (39%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y++ ++ Y +D+ A + EY D++ L P VA PH P+N E DV
Sbjct: 231 DDLTIEYMKEHSTKEYTVYEADEDAEYDEEYTIDLSTLRPTVAFPHLPENTRTIDEVGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AAK+ G++V V + PATQ +++
Sbjct: 291 KIDQVVIGSCTNGRIEDMRTAAKIL---EGREVAKGVRCIVFPATQAIYLQCIE------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F +AGC ++P+CG CLGG A+ + V+TTNRNF GRMG E E
Sbjct: 342 --EGIMTTFIKAGC-AVSTPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGDPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[101][TOP]
>UniRef100_A5MZ75 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
kluyveri DSM 555 RepID=LEUC_CLOK5
Length = 420
Score = 125 bits (313), Expect = 3e-27
Identities = 75/194 (38%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ ++ Y +D+ A ++ D++K+ P VA PH P+N E ++
Sbjct: 231 DEKTIEYVKEHSNRSYTVYEADEDAEYVKTIEIDLSKIPPTVAFPHIPENTRTIDEVGEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AAKV G+KV V T + PATQ +++
Sbjct: 291 KIDQVVIGSCTNGRIGDLRVAAKVL---KGRKVNSNVRTIIFPATQSIYLQAMK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF E+G ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 342 --EGLLEIFIESGA-VVSTPTCGPCLGGHMGILAK---GERAVATTNRNFTGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAV 409
[102][TOP]
>UniRef100_B8I4G0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
cellulolyticum H10 RepID=B8I4G0_CLOCE
Length = 419
Score = 124 bits (311), Expect = 5e-27
Identities = 75/194 (38%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ + Y +D+ A + Y D+ +++P VA PH P+N D+
Sbjct: 231 DEKTVEYVKEHSIRHYTVYKADEDAEYSEVYEIDLAEVKPTVAFPHLPENARTIDNVGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA V G+KV V ++PATQK+W +
Sbjct: 291 KIDQVVIGSCTNGRIEDMRIAAGVL---KGRKVSDNVRCIIIPATQKIWKQAMN------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG A+ + V+TTNRNF GRMGH E E
Sbjct: 342 --EGLFDIFIDAGA-AVSTPTCGPCLGGHMGILAK---GERAVATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLA P AAASA+
Sbjct: 396 VYLAGPAVAAASAV 409
[103][TOP]
>UniRef100_A4XJ48 3-isopropylmalate dehydratase large subunit n=1
Tax=Caldicellulosiruptor saccharolyticus DSM 8903
RepID=LEUC_CALS8
Length = 429
Score = 124 bits (311), Expect = 5e-27
Identities = 74/195 (37%), Positives = 110/195 (56%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T +Y++ ++ PY+ +D+ A + Y D++K+ P VA PH P+N E +
Sbjct: 233 DEKTIEYVKQHSTKPYKIFKADEDAEYSEVYEIDISKIRPTVAFPHLPENTKTIDEITEK 292
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+ I++V IGSCT G+ ED AAK+ G+KVK + + PATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK---GRKVKKGLRCIIFPATQNIYKQALK----- 344
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF +AGC ++P+CG CLGG A E + ++TTNRNF GRMGH
Sbjct: 345 ---EGLIEIFIDAGC-VVSTPTCGPCLGGHMGILA---EGERALATTNRNFVGRMGHPNS 397
Query: 533 EIYLASPYTAAASAL 577
E+YL+SP AAASA+
Sbjct: 398 EVYLSSPAIAAASAV 412
[104][TOP]
>UniRef100_Q0AV21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Syntrophomonas
wolfei subsp. wolfei str. Goettingen RepID=Q0AV21_SYNWW
Length = 419
Score = 124 bits (310), Expect = 7e-27
Identities = 73/194 (37%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++ + P+E SD A + +DV+KLEP+VA PH P+N E V
Sbjct: 231 DEITLDYVKKRVKRPFELYQSDPDAVYFDIKEYDVSKLEPVVAFPHLPENTRPVTEATHV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
+++V IGSCT G+ ED A + G+KV ++ + P T++++++
Sbjct: 291 SLDQVVIGSCTNGRIEDMEITASLL---KGQKVHPEIRVIIFPGTREIYLEALR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG AR + ++TTNRNF GRMGH E E
Sbjct: 342 --RGYIETFIEAGA-VVSTPTCGPCLGGHMGILAR---GEKALATTNRNFVGRMGHPESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAV 409
[105][TOP]
>UniRef100_C0FIT9 Putative uncharacterized protein n=1 Tax=Clostridium sp. M62/1
RepID=C0FIT9_9CLOT
Length = 278
Score = 124 bits (310), Expect = 7e-27
Identities = 75/194 (38%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +Y++ + ++ +D+ A + + Y D++ L+P VA PH P+N E DV
Sbjct: 88 DEKAVQYMKEHSKREFQIHEADEDAEYEAVYTIDLSALKPTVAFPHLPENTKTIDEAGDV 147
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA++ G+KVK V ++PATQ +++
Sbjct: 148 AIDQVVIGSCTNGRLEDMRIAAEIL---KGRKVKKGVRCIVIPATQAIYLQCIK------ 198
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG A + CVSTTNRNF GRMGH + E
Sbjct: 199 --EGLMETFIEAGA-VVSTPTCGPCLGGYMGILA---AGERCVSTTNRNFVGRMGHVDSE 252
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 253 VYLASPAVAAASAV 266
[106][TOP]
>UniRef100_A8SZ55 Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC
27759 RepID=A8SZ55_9FIRM
Length = 461
Score = 124 bits (310), Expect = 7e-27
Identities = 74/194 (38%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y++ ++ Y +D+ A + +EY D+++L+P VA PH P+N E D+
Sbjct: 271 DELTEEYMKEHSTKSYTKYEADEDAVYDAEYTIDLSQLKPTVAFPHLPENTKTIDEVGDI 330
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AA + G+KV V ++P TQ +++
Sbjct: 331 KIDQVVIGSCTNGRISDMRIAADII---KGRKVADGVRVIVIPGTQDIYLQCIE------ 381
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG M + VSTTNRNF GRMGH + E
Sbjct: 382 --EGLMTIFVKAGA-VVSTPTCGPCLGGHMGV---MAAGERAVSTTNRNFVGRMGHVDSE 435
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 436 VYLASPAVAAASAI 449
[107][TOP]
>UniRef100_Q3ZZK0 Homoaconitate hydratase family protein n=1 Tax=Dehalococcoides sp.
CBDB1 RepID=Q3ZZK0_DEHSC
Length = 417
Score = 123 bits (309), Expect = 9e-27
Identities = 70/177 (39%), Positives = 104/177 (58%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
Y+ + +D A + D T LEP ++KPH+ DN A ARE K K+++V+IG+CTGG+
Sbjct: 243 YQPLAADVDAVYERVIEIDATALEPTISKPHTVDNTATARELKGTKLDQVFIGTCTGGRL 302
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
+D AA +F + + + + PA+QK++++ L +I +AG +
Sbjct: 303 DDLAVAAAIF-KNRKRHPQTRLIVTPASQKIYLEAIRLGY--------IEILVQAGANI- 352
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
P CGACLG + + + +VC+ST NRNF GRMG+ EG IYLAS TAAASA+
Sbjct: 353 MPPGCGACLGVHQGV---LGDGEVCLSTANRNFKGRMGNPEGFIYLASAATAAASAI 406
[108][TOP]
>UniRef100_A9BGP4 3-isopropylmalate dehydratase, large subunit n=1 Tax=Petrotoga
mobilis SJ95 RepID=A9BGP4_PETMO
Length = 419
Score = 123 bits (309), Expect = 9e-27
Identities = 77/194 (39%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ + Y V SD A + +DV+ +EP VA PH P+N E K +
Sbjct: 229 DEKTKEYLKERAVRDYTPVSSDPDASYEEVIEYDVSNIEPQVAFPHLPENTKPVTEAKRI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++ IGSCT G+ ED AA V G KV V + P TQ ++M
Sbjct: 289 KIDQSVIGSCTNGRIEDLRIAAHVL---KGHKVNSDVRCIIFPGTQDIYMQALK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E E
Sbjct: 340 --EGLIEIFIEAGA-AVSTPTCGPCLGGHMGVLAK---GEKAISTTNRNFVGRMGHPESE 393
Query: 536 IYLASPYTAAASAL 577
+YL++P AAASA+
Sbjct: 394 VYLSNPAVAAASAI 407
[109][TOP]
>UniRef100_C9LTJ0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Selenomonas
sputigena ATCC 35185 RepID=C9LTJ0_9FIRM
Length = 420
Score = 123 bits (309), Expect = 9e-27
Identities = 74/193 (38%), Positives = 105/193 (54%), Gaps = 1/193 (0%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T +Y+EG+ YE V SD A++ D++ L P+VA PH P N + +
Sbjct: 230 DEKTKEYVEGRVKGAYEPVTSDADAKYCRTVEIDLSSLRPVVAFPHLPGNTKRVMDIAEP 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 358
+KI++V IGSCT G+ ED +A + L V ++P +Q V+ + L
Sbjct: 290 IKIDQVVIGSCTNGRLEDLEISAGL-LKGHEVHPDVRCIVIPGSQAVYQEAMHLGY---- 344
Query: 359 GKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEI 538
+F +AGC A+P+CG CLGG + + CVSTTNRNF GRMGH + E+
Sbjct: 345 ----IDVFIDAGCAV-AAPTCGPCLGGYMGI---LTAGERCVSTTNRNFRGRMGHVDSEV 396
Query: 539 YLASPYTAAASAL 577
YLA P+ AAASA+
Sbjct: 397 YLAGPHVAAASAI 409
[110][TOP]
>UniRef100_C6PDK3 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermoanaerobacterium thermosaccharolyticum DSM 571
RepID=C6PDK3_CLOTS
Length = 418
Score = 123 bits (309), Expect = 9e-27
Identities = 73/194 (37%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++G+ + Y+ +D+ A ++ Y D++K++P VA PH P+N E ++
Sbjct: 229 DEITETYVKGRANRKYKVFKADKDADYVESYDIDLSKIKPQVAFPHLPENTKPIDEVGNI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D +V GKKV V + PATQ ++++
Sbjct: 289 KIDQVVIGSCTNGRISDMEVTYEVL---KGKKVHPDVRLIIFPATQDIYLECVK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG A+ + +STTNRNF GRMGH E E
Sbjct: 340 --RGYIEEFIKAGA-AVSTPTCGPCLGGHMGILAK---DERAISTTNRNFVGRMGHTESE 393
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 394 VYLASPAVAAASAI 407
[111][TOP]
>UniRef100_C4EWE6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4EWE6_9BACT
Length = 417
Score = 123 bits (309), Expect = 9e-27
Identities = 80/192 (41%), Positives = 105/192 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+ + +E VY D A + E + L PLVA P+ P N ARE +DV
Sbjct: 228 DEATLAYVAPRARRSFEPVYPDPGAAYERELTVRLDSLPPLVACPNLPSNVRPARELRDV 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+I++V+IGSCT G+ ED AAKV L V L+PA+++ D+ + G
Sbjct: 288 EIHQVFIGSCTNGRIEDLRQAAKV-LKGRRLHPSVRGVLIPASRR---DMAAAMQEG--- 340
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
++F EAG +PSCG CLGG A E +VCVST NRNF GRMGH ++Y
Sbjct: 341 --LMEVFMEAGFSI-CTPSCGPCLGGHLGILA---EGEVCVSTGNRNFTGRMGHPRSQVY 394
Query: 542 LASPYTAAASAL 577
LASP AAAS +
Sbjct: 395 LASPAVAAASGV 406
[112][TOP]
>UniRef100_Q8U2A1 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
furiosus RepID=LEUC1_PYRFU
Length = 424
Score = 123 bits (309), Expect = 9e-27
Identities = 78/196 (39%), Positives = 111/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRA-LARECK- 175
D T +Y++G+ Y+ SD+ A++ +DV+K+EP VA PH P+N +++ K
Sbjct: 232 DKKTIEYVKGRAKREYKIYKSDEDAKYYKVIEYDVSKIEPQVAFPHLPENTVPISKAAKM 291
Query: 176 DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
++KI++V IGSCT G+ ED AA+V G+KV V ++P + V+
Sbjct: 292 NIKIDQVVIGSCTNGRLEDLRMAAEVL---EGQKVAPWVRLIILPCSPTVYFKAMK---- 344
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ +IF EAG P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 345 ----EGLLEIFLEAGA-VIGPPTCGPCLGGHMGILA---SGERAVSTTNRNFVGRMGHPK 396
Query: 530 GEIYLASPYTAAASAL 577
E+YLASPY AAASA+
Sbjct: 397 SEVYLASPYVAAASAI 412
[113][TOP]
>UniRef100_C0CLF7 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
DSM 10507 RepID=C0CLF7_9FIRM
Length = 422
Score = 123 bits (308), Expect = 1e-26
Identities = 74/195 (37%), Positives = 111/195 (56%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARECKD 178
D + Y+ + ++ +D+ A + EY D+++L+P +A PH P+N R + D
Sbjct: 231 DDLAVAYMREHSKREFKIYEADEDAVYEEEYTIDLSQLKPTIAFPHLPENTRTIDEITAD 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
V I++ IGSCT G+ ED AA++ G+KVK + ++PATQ +++
Sbjct: 291 VVIDQSVIGSCTNGRMEDLRIAAEILK---GRKVKKGIRCIVIPATQAIYLQAMK----- 342
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF EAG ++P+CG CLGG A E + C+STTNRNF GRMGH +
Sbjct: 343 ---EGLLEIFIEAGA-VVSTPTCGPCLGGYMGILA---EGERCISTTNRNFVGRMGHVDS 395
Query: 533 EIYLASPYTAAASAL 577
E+YLASP AAASA+
Sbjct: 396 EVYLASPAVAAASAV 410
[114][TOP]
>UniRef100_C9KJM7 3-isopropylmalate dehydratase, large subunit n=2 Tax=Mitsuokella
multacida DSM 20544 RepID=C9KJM7_9FIRM
Length = 420
Score = 122 bits (307), Expect = 2e-26
Identities = 73/195 (37%), Positives = 109/195 (55%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D +T Y++ + + PYE V +D A + E ++++L+P+VA PH P N + K+
Sbjct: 230 DEITKAYVDARVTKPYEPVAADDDAEYCREVDINLSELKPVVAFPHLPGNTKRVEDIKEP 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPG 352
++I++V IGSCT G+ ED AA + G KV +V ++P + ++ +
Sbjct: 290 IEIDQVIIGSCTNGRLEDMEIAASILK---GHKVADRVRCIVIPGSPAIYKE-------- 338
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
S + F +AGC ++P+CG CLGG A CVSTTNRNF GRMGH +
Sbjct: 339 SMKRGYIDTFIDAGCAV-STPTCGPCLGGYMGIMAAGER---CVSTTNRNFRGRMGHVDS 394
Query: 533 EIYLASPYTAAASAL 577
E+YLA P AAASA+
Sbjct: 395 EVYLAGPQVAAASAI 409
[115][TOP]
>UniRef100_C8WM14 3-isopropylmalate dehydratase, large subunit n=2 Tax=Eggerthella
lenta DSM 2243 RepID=C8WM14_9ACTN
Length = 422
Score = 122 bits (306), Expect = 2e-26
Identities = 74/192 (38%), Positives = 99/192 (51%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL+G+T PY +SD A + Y D + P V+ PH P N A E +DV
Sbjct: 233 DDVTRAYLDGRTERPYTEYHSDADATYAKVYEIDAASIVPTVSFPHLPSNTRPAAEARDV 292
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++ IGSCT G+ D AA V L V ++PATQ V+
Sbjct: 293 KIDQAVIGSCTNGRIADMRQAADV-LRGRTVHPDVRCIVIPATQAVYRQCME-------- 343
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +F +A C ++P+CG CLGG A + ++TTNRNF GRMG E+Y
Sbjct: 344 EGLMDVFLDANC-AVSTPTCGPCLGGYMGILA---AGERAIATTNRNFVGRMGDPTSEVY 399
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 400 LSSPAIAAASAV 411
[116][TOP]
>UniRef100_UPI00019E5A8A 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum acetoxidans DSM 771
RepID=UPI00019E5A8A
Length = 310
Score = 122 bits (305), Expect = 3e-26
Identities = 74/194 (38%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y+EG+ PY SD A + R+D +K+EPLVA PH P+N + V
Sbjct: 121 DEITRAYVEGRVKKPYTFYKSDADAVYSDIRRYDASKIEPLVAFPHLPENTRPVSQAGLV 180
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
++++V IGSCT G+ ED AA V GKKV ++ ++P TQ+++
Sbjct: 181 ELDQVVIGSCTNGRMEDLRLAAGVL---KGKKVSDRIRLIVIPGTQQIYKQAMR------ 231
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +AG ++P+CG CLGG A+ + ++TTNRNF GRMG E E
Sbjct: 232 --EGLIEIFIDAG-GAVSTPTCGPCLGGYMGILAK---GERSLATTNRNFVGRMGSPESE 285
Query: 536 IYLASPYTAAASAL 577
+YL +P AAASA+
Sbjct: 286 VYLCNPAVAAASAI 299
[117][TOP]
>UniRef100_C8W661 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum acetoxidans DSM 771
RepID=C8W661_9FIRM
Length = 420
Score = 122 bits (305), Expect = 3e-26
Identities = 74/194 (38%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y+EG+ PY SD A + R+D +K+EPLVA PH P+N + V
Sbjct: 231 DEITRAYVEGRVKKPYTFYKSDADAVYSDIRRYDASKIEPLVAFPHLPENTRPVSQAGLV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
++++V IGSCT G+ ED AA V GKKV ++ ++P TQ+++
Sbjct: 291 ELDQVVIGSCTNGRMEDLRLAAGVL---KGKKVSDRIRLIVIPGTQQIYKQAMR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +AG ++P+CG CLGG A+ + ++TTNRNF GRMG E E
Sbjct: 342 --EGLIEIFIDAG-GAVSTPTCGPCLGGYMGILAK---GERSLATTNRNFVGRMGSPESE 395
Query: 536 IYLASPYTAAASAL 577
+YL +P AAASA+
Sbjct: 396 VYLCNPAVAAASAI 409
[118][TOP]
>UniRef100_A6UTQ6 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
aeolicus Nankai-3 RepID=A6UTQ6_META3
Length = 425
Score = 122 bits (305), Expect = 3e-26
Identities = 72/181 (39%), Positives = 100/181 (55%)
Frame = +2
Query: 35 TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCT 214
T+ PY ++ D+ A+F Y +V LEPL A PH+ DN ARE I++V+IGSCT
Sbjct: 247 TTRPYTALKGDEDAKFEETYEIEVNDLEPLFACPHAVDNVKTAREVAGRPIDQVFIGSCT 306
Query: 215 GGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAG 394
G+ ED AA + GG V + PA+++V ++ + + Q F E G
Sbjct: 307 NGRVEDLRAAINIIDQHGGIADDVRVVVTPASREVMLEAIN--------EGIIQKFYEYG 358
Query: 395 CDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASA 574
C +PSC AC+G Y + +V V+T+NRNF GR G E E+YLASP TAAA A
Sbjct: 359 C-VVTNPSCSACMGA---LYGILGPNEVGVATSNRNFRGREGSLESEVYLASPITAAACA 414
Query: 575 L 577
+
Sbjct: 415 V 415
[119][TOP]
>UniRef100_C4FI11 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium yellowstonense SS-5
RepID=C4FI11_9AQUI
Length = 431
Score = 121 bits (304), Expect = 3e-26
Identities = 73/194 (37%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +++ +T ++ SD A++ EY FD +K+EP+VA P P N E
Sbjct: 231 DEKTVEWVRKRTDREFKLYKSDPDAKYCCEYEFDASKIEPVVACPSLPSNVKPVSEVAGT 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V+IGSCT G+ D AA + GKKV +V ++PA+ +++
Sbjct: 291 HIDQVFIGSCTNGRLSDLRIAAAIL---KGKKVHPEVRCIVIPASDQIYKQALH------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +I EAGC S +CG CLGG A E +VC+ST+NRNF GRMGH + +
Sbjct: 342 --EGIIEILAEAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQ 395
Query: 536 IYLASPYTAAASAL 577
+YL+SP AAASA+
Sbjct: 396 VYLSSPAVAAASAV 409
[120][TOP]
>UniRef100_B1QZX5 3-isopropylmalate dehydratase, large subunit n=2 Tax=Clostridium
butyricum RepID=B1QZX5_CLOBU
Length = 419
Score = 121 bits (304), Expect = 3e-26
Identities = 74/194 (38%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ ++ +D+ A++ Y D++ L P V+ PH PDN DV
Sbjct: 231 DEKTEEYLKDHAKREWKKYEADEDAQYDEVYEIDLSTLRPTVSFPHLPDNTRTIDNTGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D A + GKKV + ++P TQK+++
Sbjct: 291 KIDQVVIGSCTNGRISDLRVARDIL---KGKKVDKTIRCIVIPGTQKIYLQALE------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E E
Sbjct: 342 --EGIIKDLIEAGA-IVSTPTCGPCLGGHMGILAK---DERCVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAI 409
[121][TOP]
>UniRef100_B9MLV4 3-isopropylmalate dehydratase large subunit n=1 Tax=Anaerocellum
thermophilum DSM 6725 RepID=LEUC_ANATD
Length = 429
Score = 121 bits (304), Expect = 3e-26
Identities = 72/195 (36%), Positives = 110/195 (56%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T +Y++ ++ PY+ +D+ A + + D++K+ P VA PH P+N E +
Sbjct: 233 DEKTIEYVKQHSTKPYKIFKADEDAEYSQVFEIDISKIRPTVAFPHLPENTKTIDEITEK 292
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+ I++V IGSCT G+ ED AAK+ G+KVK + + PATQ ++
Sbjct: 293 IYIDQVVIGSCTNGRIEDLRIAAKILK---GRKVKKGLRCIIFPATQNIYKQALK----- 344
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF +AGC ++P+CG CLGG A + + ++TTNRNF GRMGH
Sbjct: 345 ---EGFIEIFIDAGC-VVSTPTCGPCLGGHMGILA---DGEKALATTNRNFVGRMGHPNS 397
Query: 533 EIYLASPYTAAASAL 577
E+YL+SP AAASA+
Sbjct: 398 EVYLSSPAIAAASAV 412
[122][TOP]
>UniRef100_C1DUH4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium azorense Az-Fu1
RepID=C1DUH4_SULAA
Length = 431
Score = 121 bits (303), Expect = 4e-26
Identities = 72/194 (37%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +++ +T+ ++ SD A++ EY FD K+EP+VA P+ P N E
Sbjct: 231 DEKTIEWVRKRTNREFKIYKSDPDAKYCCEYEFDANKIEPVVACPNLPSNVKPVSEVAGT 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V+IGSCT G+ D AA + GKKV +V ++PA+ +++
Sbjct: 291 HIDQVFIGSCTNGRLSDLRIAAAIL---KGKKVHPEVRCIVIPASDQIYKQALH------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH + +
Sbjct: 342 --EGIIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQ 395
Query: 536 IYLASPYTAAASAL 577
+YL+SP AAASA+
Sbjct: 396 VYLSSPAVAAASAV 409
[123][TOP]
>UniRef100_A8AB09 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ignicoccus
hospitalis KIN4/I RepID=A8AB09_IGNH4
Length = 419
Score = 121 bits (303), Expect = 4e-26
Identities = 77/194 (39%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT K+ E + + + D A++ + FDV+KLEP VA PHS DN E +
Sbjct: 231 DEVTVKFFE-EAGISVKPFGPDPGAQYEDVWEFDVSKLEPQVAVPHSVDNVVAVGEVEGT 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++ +IGSCT G+ EDF+ AAK+ G+KV V +PA+ K +M +
Sbjct: 290 PIDQAFIGSCTNGRYEDFVEAAKIL---KGRKVAPGVRCIAIPASLKQYMRLLK------ 340
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ I EAGC A +CG CLGG + +V +S++NRNF GRMGH E +
Sbjct: 341 --EGIIDILTEAGCFV-AHSTCGPCLGGHLGV---LGPGEVAISSSNRNFKGRMGHPESK 394
Query: 536 IYLASPYTAAASAL 577
+YLASP T AASA+
Sbjct: 395 VYLASPATVAASAV 408
[124][TOP]
>UniRef100_B1H0A6 3-isopropylmalate dehydratase large subunit n=1 Tax=uncultured
Termite group 1 bacterium phylotype Rs-D17
RepID=LEUC_UNCTG
Length = 420
Score = 121 bits (303), Expect = 4e-26
Identities = 73/194 (37%), Positives = 103/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y+ + Y+ SD+ A++L Y D +K+ P V+ P P N ++ K
Sbjct: 231 DEITENYVAKRAQRKYKFYISDKDAKYLKIYEIDCSKILPQVSMPFLPSNTKAVKDIKKT 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA + GKKV V T ++PAT +V+
Sbjct: 291 YIDQVVIGSCTNGRIEDLRVAASII--KKGKKVNSNVRTLIIPATPEVYSQALD------ 342
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +AG A P+CG CLGG A + C STTNRNF GRMGH E +
Sbjct: 343 --EGLLRIFMDAGAIISA-PTCGPCLGGHMGILA---SGEKCASTTNRNFRGRMGHVESQ 396
Query: 536 IYLASPYTAAASAL 577
++L +P AAASA+
Sbjct: 397 LFLVNPAVAAASAI 410
[125][TOP]
>UniRef100_P81291 Isopropylmalate/citramalate isomerase large subunit n=1
Tax=Methanocaldococcus jannaschii RepID=LEUC_METJA
Length = 424
Score = 121 bits (303), Expect = 4e-26
Identities = 70/181 (38%), Positives = 97/181 (53%)
Frame = +2
Query: 35 TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCT 214
T P+E + D+ A F Y + K+EP+ A PH+ DN ARE I++V+IGSCT
Sbjct: 246 TERPFEVIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVKQAREVAGKPIDQVFIGSCT 305
Query: 215 GGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAG 394
G+ ED A K+ GG V + PA+++ ++ + + F + G
Sbjct: 306 NGRLEDLRMAIKIIEKHGGIADDVRVVVTPASREEYLKALK--------EGIIEKFLKYG 357
Query: 395 CDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASA 574
C +PSC AC+G Y + +VCVST+NRNF GR G E EIYLASP TAAA A
Sbjct: 358 C-VVTNPSCSACMG---SLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACA 413
Query: 575 L 577
+
Sbjct: 414 V 414
[126][TOP]
>UniRef100_A9KT79 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
phytofermentans ISDg RepID=LEUC_CLOPH
Length = 421
Score = 121 bits (303), Expect = 4e-26
Identities = 74/194 (38%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++ + PY +D+ A + ++++LEP VA PH P+N +E +V
Sbjct: 231 DDLTISYMKEHGAKPYTIYEADEDAEYEQIITINLSELEPTVAFPHLPENTKTVKEAGEV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+I++V IGSCT G+ D AAKV G+KV + + PATQ +++
Sbjct: 291 RIDQVVIGSCTNGRIGDLRIAAKVL---EGRKVAKGMRAIVFPATQAIYLQAIE------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ Q F +AGC ++P+CG CLGG A + STTNRNF GRMGH E E
Sbjct: 342 --EGLIQTFIKAGC-VVSTPTCGPCLGGHMGILA---AGERAASTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YL SP AAASA+
Sbjct: 396 VYLCSPAVAAASAV 409
[127][TOP]
>UniRef100_A6LPX4 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
beijerinckii NCIMB 8052 RepID=LEUC_CLOB8
Length = 419
Score = 121 bits (303), Expect = 4e-26
Identities = 75/194 (38%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ S ++ +D+ A + + D+++L P V+ PH PDN DV
Sbjct: 231 DDKTEEYLKDHASREWKVYEADEDAEYDKVFEIDLSELRPTVSFPHLPDNTRTIDNTGDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D A + GKKVK + ++P TQK+++ +
Sbjct: 291 AIDQVVIGSCTNGRISDLRMARDIL---KGKKVKKGIRCIVIPGTQKIYLQAIKEGIVTD 347
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
EAG ++P+CG CLGG A+ + CVSTTNRNF GRMGH E E
Sbjct: 348 --------LVEAGA-AFSTPTCGPCLGGHMGILAK---GERCVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASAL
Sbjct: 396 VYLASPAVAAASAL 409
[128][TOP]
>UniRef100_A7VIP8 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
RepID=A7VIP8_9CLOT
Length = 441
Score = 120 bits (302), Expect = 6e-26
Identities = 74/194 (38%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++ ++ Y+ +D A + EY D++ L P VA PH P+N E D+
Sbjct: 251 DELTEAYMKEHSTKAYKKYEADADAVYDEEYTIDLSTLRPTVAFPHLPENTKTIDEVGDI 310
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AA + G++V V ++P TQ+V++
Sbjct: 311 KIDQVVIGSCTNGRISDMRIAADII---KGRQVAPGVRVIVIPGTQEVYLQCIE------ 361
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG M + VSTTNRNF GRMGH + E
Sbjct: 362 --EGLMTIFVKAGA-VVSTPTCGPCLGGHMGV---MAAGERAVSTTNRNFVGRMGHVDSE 415
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 416 VYLASPAVAAASAI 429
[129][TOP]
>UniRef100_Q24XT4 3-isopropylmalate dehydratase large subunit n=2
Tax=Desulfitobacterium hafniense RepID=LEUC_DESHY
Length = 421
Score = 120 bits (301), Expect = 8e-26
Identities = 73/194 (37%), Positives = 105/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+ + PY+ +SD A+++ Y +DV + VA PH P+N E K +
Sbjct: 232 DEKTLAYVNERAKRPYKVYHSDPDAQYVEVYEWDVADIPLQVAFPHLPENAKPVSEGKGI 291
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ ED AA++ G+KV V ++P TQ ++
Sbjct: 292 KIDQVVIGSCTNGRLEDMQVAAQIL---KGQKVHGDVRLIVIPGTQDIYKQAMQ------ 342
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG ++P+CG CLGG A+ + +STTNRNF GRMGH E E
Sbjct: 343 --EGLIDIFIDAGA-VVSTPTCGPCLGGYMGILAK---GERALSTTNRNFVGRMGHPESE 396
Query: 536 IYLASPYTAAASAL 577
+YL+ P AAASA+
Sbjct: 397 VYLSGPAVAAASAV 410
[130][TOP]
>UniRef100_C4GAI7 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
DSM 14600 RepID=C4GAI7_9FIRM
Length = 434
Score = 120 bits (301), Expect = 8e-26
Identities = 71/174 (40%), Positives = 102/174 (58%), Gaps = 2/174 (1%)
Frame = +2
Query: 62 SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKTEDFMA 241
+D A + +EY D++ L+P V+ PH P+N + +D+ I++V IGSCT G+ D A
Sbjct: 265 ADADADYAAEYTIDLSSLKPTVSFPHLPENTRTIDQIEDIAIDQVVIGSCTNGRLSDLKA 324
Query: 242 AAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTPASP 415
AA++ G+KV +V T ++PATQ++++D + F EAG ++P
Sbjct: 325 AAEIL---KGRKVADRVRTIIIPATQQIYLDAMQAGY--------LKTFIEAGA-VVSTP 372
Query: 416 SCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+CG CLGG A + CVSTTNRNF GRMG E+YLASP AAASA+
Sbjct: 373 TCGPCLGGYMGILA---AGERCVSTTNRNFVGRMGDVTSEVYLASPAVAAASAV 423
[131][TOP]
>UniRef100_A5IJM1 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IJM1_THEP1
Length = 417
Score = 120 bits (300), Expect = 1e-25
Identities = 74/196 (37%), Positives = 108/196 (55%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D +T Y E + + E +Y D+ A+++ E D+++LEP VA P P N E +
Sbjct: 228 DEITIAY-ERERGIEVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKE 286
Query: 179 -VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
+KI++ IGSCT G+ ED AA++ G+ V V ++P +QKV+
Sbjct: 287 RIKIDQAVIGSCTNGRIEDLRLAAQILK---GRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 530 GEIYLASPYTAAASAL 577
+++LASP AAASA+
Sbjct: 392 SKVFLASPAVAAASAI 407
[132][TOP]
>UniRef100_A5KNQ3 Putative uncharacterized protein n=1 Tax=Ruminococcus torques ATCC
27756 RepID=A5KNQ3_9FIRM
Length = 451
Score = 120 bits (300), Expect = 1e-25
Identities = 78/195 (40%), Positives = 101/195 (51%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T +YL+ PY +D+ A + D++K+ P VA PH P N E +
Sbjct: 237 DEKTVEYLDAHCEKPYTVYEADEDAVYDDVVEIDLSKVRPTVAFPHLPGNAKTIDEIEAE 296
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPG 352
VKI++V IGSCT G+ ED AA + L V +VPATQK++
Sbjct: 297 EQVKIDQVVIGSCTNGRMEDMRKAAAI-LKGHTVHPDVRVMVVPATQKIYKQCIK----- 350
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 351 ---EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAAGEK---CVSTTNRNFVGRMGHVDS 403
Query: 533 EIYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 404 LIYLASPEVAAASAI 418
[133][TOP]
>UniRef100_C9RGT8 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
vulcanius M7 RepID=C9RGT8_9EURY
Length = 422
Score = 120 bits (300), Expect = 1e-25
Identities = 69/181 (38%), Positives = 97/181 (53%)
Frame = +2
Query: 35 TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCT 214
T P+E + D+ A F Y + K+EP+ A PH+ DN ARE I++V+IGSCT
Sbjct: 244 TERPFEIIKGDEDAEFEEVYEIEADKIEPVFACPHNVDNVKQAREVAGRPIDQVFIGSCT 303
Query: 215 GGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAG 394
G+ ED A +V GG + + PA+++ ++ + + F + G
Sbjct: 304 NGRVEDLRMAIEVIEKHGGIADNIRVIITPASREEYLKALK--------EGIIEKFLKYG 355
Query: 395 CDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASA 574
C +PSC AC+G Y + +VCVST+NRNF GR G E EIYLASP TAAA A
Sbjct: 356 C-VVTNPSCSACMG---SLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACA 411
Query: 575 L 577
+
Sbjct: 412 V 412
[134][TOP]
>UniRef100_A0RMG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
fetus subsp. fetus 82-40 RepID=LEUC_CAMFF
Length = 421
Score = 120 bits (300), Expect = 1e-25
Identities = 83/198 (41%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +2
Query: 2 DSVTYKYLEGKT--SVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC- 172
D +T ++LE K S P + YSD+ A + R DV+KL+P++A P P N E
Sbjct: 230 DDITKEFLESKNLRSKP-KFHYSDEGANYEQVLRIDVSKLDPVIAYPFLPSNGKSINEAL 288
Query: 173 -KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLP 343
D+KI++V+IGSCT G+ D AA++ GK+V T L+ PATQK+ +L
Sbjct: 289 KDDLKIDQVFIGSCTNGRLSDLRIAARILK---GKRVAKHTRLIITPATQKI-----ALA 340
Query: 344 VPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGH 523
G IF EAG ++P+CGACLGG + + CVSTTNRNF GRMG
Sbjct: 341 AQKEG---LMDIFVEAGA-VVSNPTCGACLGGYMGI---LGAGERCVSTTNRNFVGRMGD 393
Query: 524 REGEIYLASPYTAAASAL 577
R E+YLA+ AAASA+
Sbjct: 394 RTSEVYLANSAVAAASAI 411
[135][TOP]
>UniRef100_Q9WZ24 3-isopropylmalate dehydratase large subunit 2 n=2 Tax=Thermotoga
RepID=LEUC2_THEMA
Length = 417
Score = 120 bits (300), Expect = 1e-25
Identities = 74/196 (37%), Positives = 108/196 (55%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D +T Y E + + E +Y D+ A+++ E D+++LEP VA P P N E +
Sbjct: 228 DEITIAY-ERERGIEVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKE 286
Query: 179 -VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
+KI++ IGSCT G+ ED AA++ G+ V V ++P +QKV+
Sbjct: 287 RIKIDQAVIGSCTNGRIEDLRLAAQILK---GRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ IF +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDIFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 530 GEIYLASPYTAAASAL 577
+++LASP AAASA+
Sbjct: 392 SKVFLASPAVAAASAI 407
[136][TOP]
>UniRef100_O28084 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Archaeoglobus
fulgidus RepID=LEUC2_ARCFU
Length = 416
Score = 120 bits (300), Expect = 1e-25
Identities = 71/179 (39%), Positives = 105/179 (58%), Gaps = 2/179 (1%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
+ V +D+ A + E DV+ L P+V+KPH+ DN A E + ++N+VYIG+CT G+
Sbjct: 242 FREVKADEDAEYEKEIYMDVSSLVPVVSKPHNVDNVAEISEVEGTEVNQVYIGTCTNGRL 301
Query: 227 EDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCD 400
D AA++ G+KVK V +VPA+++V++ K ++F EAG
Sbjct: 302 SDLEVAARIL---KGRKVKEGVRLIVVPASRRVYLQALD--------KGLIRVFVEAG-G 349
Query: 401 TPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+P CG C+G + A + +VC+ST NRNF GRMG+ EI+LASP TAAASA+
Sbjct: 350 MVLNPGCGPCVGIHQGILA---DGEVCISTQNRNFKGRMGNPNAEIFLASPATAAASAV 405
[137][TOP]
>UniRef100_C7I822 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermotoga
naphthophila RKU-10 RepID=C7I822_9THEM
Length = 417
Score = 119 bits (299), Expect = 1e-25
Identities = 73/196 (37%), Positives = 108/196 (55%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D +T Y E + + E +Y D+ A+++ E D+++LEP VA P P N E +
Sbjct: 228 DEITIAY-ERERGIEVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKE 286
Query: 179 -VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
+KI++ IGSCT G+ ED AA++ G+ V V ++P +QKV+
Sbjct: 287 RIKIDQAVIGSCTNGRIEDLRLAAQILK---GRTVSPDVRCIIIPGSQKVYKQALK---- 339
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ +F +AGC ++P+CG CLGG A E +V +STTNRNF GRMGH
Sbjct: 340 ----EGLIDVFIDAGCAV-STPTCGPCLGGHMGVLA---EGEVAISTTNRNFVGRMGHPN 391
Query: 530 GEIYLASPYTAAASAL 577
+++LASP AAASA+
Sbjct: 392 SKVFLASPAVAAASAI 407
[138][TOP]
>UniRef100_C1I927 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I927_9CLOT
Length = 424
Score = 119 bits (299), Expect = 1e-25
Identities = 75/194 (38%), Positives = 102/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT +YL ++ +D+ A + Y D++KL P VA PH PDN E +V
Sbjct: 231 DDVTIRYLVDHAQREWKVYEADEDAEYDEVYEIDLSKLRPTVAFPHLPDNTRTIDEVGEV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+++V IGSCT G+ D A + KKVK V + P TQK+++
Sbjct: 291 AVDQVVIGSCTNGRISDLRVARDIL---KNKKVKKGVRCIVFPGTQKIYLQALE------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + EAG ++P+CG CLGG A+ + +STTNRNF GRMGH E E
Sbjct: 342 --EGIIKDLVEAGA-VVSTPTCGPCLGGHMGILAK---GERAISTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASAL
Sbjct: 396 VYLASPAVAAASAL 409
[139][TOP]
>UniRef100_A0B7A3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7A3_METTP
Length = 382
Score = 119 bits (299), Expect = 1e-25
Identities = 67/186 (36%), Positives = 110/186 (59%)
Frame = +2
Query: 20 YLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVY 199
YL + PY ++SD + + E +DV+ + P++A P+ DN R+ +++++V+
Sbjct: 204 YLARRARRPYTHIHSDPGS-YYREIEYDVSDIPPMIAAPYRVDNVHPVRDLAGIEVDQVF 262
Query: 200 IGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQI 379
IG+CT G+ ED AA++ GK+VK+ T ++PA++++++ G+ +
Sbjct: 263 IGTCTNGRLEDLEMAARIV---KGKRVKIRTLVIPASREIYL--------GALRSGVIET 311
Query: 380 FEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYT 559
EAG P CG CLG + + +VC+ST+NRNFPGRMG R G++YLASP T
Sbjct: 312 LVEAGA-MIGPPGCGPCLGAHMGV---LGDGEVCLSTSNRNFPGRMG-RNGKVYLASPAT 366
Query: 560 AAASAL 577
AAA+A+
Sbjct: 367 AAATAI 372
[140][TOP]
>UniRef100_C7P908 3-isopropylmalate dehydratase n=1 Tax=Methanocaldococcus fervens
AG86 RepID=C7P908_METFA
Length = 420
Score = 119 bits (299), Expect = 1e-25
Identities = 74/201 (36%), Positives = 104/201 (51%), Gaps = 9/201 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV---------YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNR 154
D +TY YL+ + + E + + +A + E D+T +E VA PH PDN
Sbjct: 224 DEITYNYLKNERGLSDEKIAELKKERITVNKDEANYYREIEIDITDMEEQVAVPHHPDNV 283
Query: 155 ALARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVY 334
E + +IN+V+IGSCT G+ D AAK +L G V ++PA++KV++
Sbjct: 284 KPVSEVEGTEINQVFIGSCTNGRLSDLREAAK-YLKGGKVHKDVKLIVIPASKKVFLQAL 342
Query: 335 SLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGR 514
+ + F +AG +P CG CLG + A E +VC+STTNRNF GR
Sbjct: 343 R--------EGLIETFIKAGA-MICTPGCGPCLGAHQGVLA---EGEVCLSTTNRNFRGR 390
Query: 515 MGHREGEIYLASPYTAAASAL 577
MGH IYLASP AA SA+
Sbjct: 391 MGHINSYIYLASPKVAAISAV 411
[141][TOP]
>UniRef100_B5IER5 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IER5_9EURY
Length = 418
Score = 119 bits (299), Expect = 1e-25
Identities = 71/194 (36%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YL+ + PYE ++ D+ A + Y +D + L P +A PH+ DN + + +
Sbjct: 229 DEKTEAYLKTRARAPYEIMHPDEDAEYERRYEYDASDLVPKIAFPHTVDNVYDIDKAEGI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
++N+V++G+CT G+ ED AA++ GKKV V + PA+ VW + +
Sbjct: 289 EVNQVFLGTCTNGRVEDLEIAARIL---KGKKVNKNVRMLVFPASWDVWRE--------A 337
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
K + EAG +P CG CLG A + + C+ST NRNF GRMG+ E
Sbjct: 338 DEKGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPNAE 393
Query: 536 IYLASPYTAAASAL 577
IYL SP TAAA+AL
Sbjct: 394 IYLGSPATAAATAL 407
[142][TOP]
>UniRef100_C0D3T2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
DSM 15981 RepID=C0D3T2_9CLOT
Length = 446
Score = 119 bits (298), Expect = 2e-25
Identities = 73/194 (37%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YL+ + ++ +D A + + Y D+++L+P V+ PH P N DV
Sbjct: 257 DEQTVAYLKEHSKRDFKVYEADPDAEYDATYVIDLSELKPTVSFPHLPSNTRTIDNVGDV 316
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++ IGSCT G+ +D AA++ G+KV V ++PATQ +++
Sbjct: 317 KIDQSVIGSCTNGRIDDMRVAAEIL---KGRKVAKNVRCIVIPATQAIYLQAMR------ 367
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH + E
Sbjct: 368 --EGLLEIFVEAGA-IVSTPTCGPCLGGYMGILA---AGERCISTTNRNFVGRMGHVDSE 421
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 422 VYLASPAVAAASAV 435
[143][TOP]
>UniRef100_A8RZ58 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
BAA-613 RepID=A8RZ58_9CLOT
Length = 420
Score = 119 bits (298), Expect = 2e-25
Identities = 70/194 (36%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D + +Y++ + + +D+ A + Y D+++L+P V+ PH P N + +V
Sbjct: 231 DELAVEYMKEHSKREFTVYEADEDAEYDETYVIDLSELKPTVSFPHLPSNTRTIDQVGEV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
K+++ IGSCT G+ ED AA+V G+K+ V ++PATQ +++
Sbjct: 291 KVDQAVIGSCTNGRIEDMRIAAEVL---KGRKIAKGVRCIVIPATQSIYLQAMK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF EAG ++P+CG CLGG A + C+STTNRNF GRMGH + E
Sbjct: 342 --EGLLEIFIEAGA-VVSTPTCGPCLGGYMGILA---AGERCISTTNRNFVGRMGHVDSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAV 409
[144][TOP]
>UniRef100_Q6LY44 3-isopropylmalate dehydratase n=1 Tax=Methanococcus maripaludis
RepID=Q6LY44_METMP
Length = 424
Score = 119 bits (298), Expect = 2e-25
Identities = 69/197 (35%), Positives = 104/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEG-----KTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAR 166
D T Y++ T+ P+E V D+ A F ++ DV+ LEP++A PH+ DN R
Sbjct: 230 DDKTINYVKNAMEANNTAKPFELVLGDKNAEFEEKFEIDVSNLEPVMACPHNVDNVKAVR 289
Query: 167 ECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPV 346
E I++V+IGSCT G+ ED AA V GG + + PA++ + ++
Sbjct: 290 EVAGTPIDQVFIGSCTNGRLEDLRAALNVIEKHGGISKDIRVVVTPASRSIMLEAID--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F + GC +PSC AC+G Y + +V ++T+NRNF GR G
Sbjct: 347 -----EGLIKKFYQYGC-VVTNPSCSACMGA---LYGLLGPGEVGIATSNRNFRGREGSL 397
Query: 527 EGEIYLASPYTAAASAL 577
E ++YLASP TAAA A+
Sbjct: 398 ESDVYLASPITAAACAV 414
[145][TOP]
>UniRef100_A4FX22 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanococcus
maripaludis C5 RepID=A4FX22_METM5
Length = 424
Score = 119 bits (298), Expect = 2e-25
Identities = 68/197 (34%), Positives = 105/197 (53%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEG-----KTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAR 166
D T Y++ T+ P+E + D+ A F ++ DV+ LEP++A PH+ DN R
Sbjct: 230 DDKTINYVKNAMEMNNTAKPFEFILGDKDAEFEKKFEIDVSNLEPVMACPHNVDNVKAVR 289
Query: 167 ECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPV 346
E I++V+IGSCT G+ ED AA +V GG + + PA++ + ++
Sbjct: 290 EVAGTPIDQVFIGSCTNGRLEDLRAALEVIEKHGGISKDIRVVVTPASRSIMLEAID--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F + GC +PSC AC+G Y + +V ++T+NRNF GR G
Sbjct: 347 -----EGLIKKFYQYGC-VVTNPSCSACMGA---LYGLLGPGEVGIATSNRNFRGREGSL 397
Query: 527 EGEIYLASPYTAAASAL 577
E ++YLASP TAAA A+
Sbjct: 398 ESDVYLASPITAAACAV 414
[146][TOP]
>UniRef100_C7P7J9 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
fervens AG86 RepID=C7P7J9_METFA
Length = 424
Score = 119 bits (298), Expect = 2e-25
Identities = 69/181 (38%), Positives = 97/181 (53%)
Frame = +2
Query: 35 TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCT 214
T P+E + D+ A F Y + K+EP+ A PH+ DN ARE I++V+IGSCT
Sbjct: 246 TERPFEIIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVKPAREVAGRPIDQVFIGSCT 305
Query: 215 GGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAG 394
G+ ED A ++ GG V + PA+++ ++ + + F + G
Sbjct: 306 NGRFEDLKMAIEIIDKHGGIADNVRVVVTPASREEYLKALKAGI--------IEKFLKYG 357
Query: 395 CDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASA 574
C +PSC AC+G Y + +VCVST+NRNF GR G E EIYLASP TAAA A
Sbjct: 358 C-VVTNPSCSACMG---SLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACA 413
Query: 575 L 577
+
Sbjct: 414 V 414
[147][TOP]
>UniRef100_Q97EE0 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
acetobutylicum RepID=LEUC_CLOAB
Length = 422
Score = 119 bits (298), Expect = 2e-25
Identities = 70/194 (36%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++G++ + +D+ A + D++ L+P VA PH P+N + +V
Sbjct: 233 DEKTIEYMKGRSDRELKKFDADEDAEYSRVIEIDLSTLKPTVAFPHLPENTKTIDQVGEV 292
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+++V IGSCT G+ ED AA + GKK+K + + P TQ ++++
Sbjct: 293 NVDQVVIGSCTNGRMEDLRIAASIL---KGKKIKKGIRLIVFPGTQNIYLEAME------ 343
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAG ++P+CG CLGG A E + +STTNRNF GRMGH + E
Sbjct: 344 --EGLVRTFIEAG-GIVSTPTCGPCLGGHMGILA---EGERAISTTNRNFVGRMGHPKSE 397
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 398 VYLASPAVAAASAI 411
[148][TOP]
>UniRef100_A0LMK9 3-isopropylmalate dehydratase, large subunit n=1
Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LMK9_SYNFM
Length = 419
Score = 119 bits (297), Expect = 2e-25
Identities = 77/194 (39%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT +Y++G+ YE SD A F S + +DV+ EP+VA PHSP N
Sbjct: 231 DPVTEEYVKGRAKRSYEFYRSDPDAAFESVHEWDVSAFEPMVALPHSPANVRPVSRIPRT 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA + G+KV V ++PAT++++
Sbjct: 291 VIDQVVIGSCTNGRYEDLETAAAIL---KGRKVAPGVRCMIIPATREIYRQAL------R 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
G + + EA T P+CG CLGG A + V+TTNRNF GRMGH E E
Sbjct: 342 NGLLETFVDAEAAVST---PTCGPCLGGHMGILA---AGEKAVATTNRNFLGRMGHAESE 395
Query: 536 IYLASPYTAAASAL 577
IYL++P AAASA+
Sbjct: 396 IYLSNPAVAAASAV 409
[149][TOP]
>UniRef100_C4ETQ1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4ETQ1_9BACT
Length = 420
Score = 119 bits (297), Expect = 2e-25
Identities = 66/177 (37%), Positives = 104/177 (58%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
+E++++DQ A + E + +++L P VAKPH+ DN A + K +I++ +IGSCT G+
Sbjct: 248 WEAIWADQGATYAKELSYCLSELVPGVAKPHTVDNYAPVDQVKGAQIHQAFIGSCTNGRI 307
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
ED AA + G++V V T ++PA+ +V+ + + F +AGC
Sbjct: 308 EDLREAATIL---KGRQVAVRTIVIPASWRVYRQAME--------EGLLETFLDAGC-VI 355
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
++P CG C+G + A + C+ST NRNF GRMG+++ IYLASP T AASA+
Sbjct: 356 SNPGCGPCMGNHQGILA---PGETCISTANRNFKGRMGNKDSFIYLASPLTVAASAV 409
[150][TOP]
>UniRef100_C4CQ67 3-isopropylmalate dehydratase, large subunit n=1 Tax=Sphaerobacter
thermophilus DSM 20745 RepID=C4CQ67_9CHLR
Length = 424
Score = 119 bits (297), Expect = 2e-25
Identities = 74/192 (38%), Positives = 100/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL G+T P++ SD A F R D+ + PL+A PHSP N E
Sbjct: 230 DEVTAAYLAGRTDRPWQPERSDPDASFARRVRIDLDGVPPLIALPHSPGNVVPVAEAAGR 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++VYIG+C G D AA + LA V +VPA+QKV+ + +
Sbjct: 290 KIDQVYIGNCANGTMTDLRQAASI-LAGNRVHPDVRAIIVPASQKVYREALA-------- 340
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F AG ++P+CGAC GG A + V+TTNRNF GRMG + E+Y
Sbjct: 341 EGLIDQFVAAGA-IVSTPTCGACFGGHMGVLA---AGERAVATTNRNFKGRMGSADAEVY 396
Query: 542 LASPYTAAASAL 577
LA+ Y AAA+A+
Sbjct: 397 LANAYVAAAAAV 408
[151][TOP]
>UniRef100_B1L3C3 Homoaconitate hydratase family protein n=1 Tax=Candidatus
Korarchaeum cryptofilum OPF8 RepID=B1L3C3_KORCO
Length = 384
Score = 119 bits (297), Expect = 2e-25
Identities = 78/194 (40%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL G+ YSD + E DV+ LEPLVA PHSP N A E D
Sbjct: 197 DDVTLSYLNGRLRRAPRPEYSDDGSHS-DEISIDVSSLEPLVAIPHSPANVKPASEV-DA 254
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+I++ +IGSCTGG+ +D AA++ G++VK V ++PA+++++++ +
Sbjct: 255 EIDQAFIGSCTGGRLKDLEVAARILR---GRRVKEGVRLIVIPASRRIYLEALRRGI--- 308
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
I E+G T PSCG CLG A E +V +ST+NRNF GRMGH E
Sbjct: 309 -----IDILIESGA-TIGPPSCGPCLGAHLGVLA---EGEVAISTSNRNFRGRMGHPESR 359
Query: 536 IYLASPYTAAASAL 577
+YLAS T AASA+
Sbjct: 360 VYLASAATVAASAV 373
[152][TOP]
>UniRef100_A6VG92 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C7 RepID=A6VG92_METM7
Length = 424
Score = 119 bits (297), Expect = 2e-25
Identities = 69/197 (35%), Positives = 104/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEG-----KTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAR 166
D T Y++ T+ P+E + D+ A F ++ +V LEP++A PH+ DN R
Sbjct: 230 DDKTINYVKNAMETNNTAKPFEFILGDKNAEFEEKFEIEVDNLEPVMACPHNVDNVKTVR 289
Query: 167 ECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPV 346
E I++V+IGSCT G+ ED AA KV GG + + PA++ V ++
Sbjct: 290 EVAGTPIDQVFIGSCTNGRIEDLRAALKVIEKHGGISKDIRVVVTPASRSVMLEAID--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F + GC +PSC AC+G Y + +V ++T+NRNF GR G
Sbjct: 347 -----EGLIKKFYQYGC-VVTNPSCSACMGA---LYGLLGPGEVGIATSNRNFRGREGSL 397
Query: 527 EGEIYLASPYTAAASAL 577
E ++YLASP TAAA A+
Sbjct: 398 ESDVYLASPITAAACAV 414
[153][TOP]
>UniRef100_B5IEF0 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IEF0_9EURY
Length = 418
Score = 119 bits (297), Expect = 2e-25
Identities = 68/192 (35%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YL+ + PYE ++ D+ A + Y +D + L P +A PH+ DN + + +
Sbjct: 229 DEKTEAYLKTRARAPYEIMHPDEDAEYERRYEYDASDLVPKIAFPHTVDNVYDIDKAEGI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++N+V++G+CT G+ ED AA++ + K V + PA+ VW + +
Sbjct: 289 EVNQVFLGTCTNGRVEDLEVAARILKGNKVNK-NVRMLVFPASWDVWRE--------ANE 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K + EAG +P CG CLG A + + C+ST NRNF GRMG+ EIY
Sbjct: 340 KGILRTLAEAGA-VIMNPGCGPCLGAHAGVLA---DGEKCLSTANRNFKGRMGNPNAEIY 395
Query: 542 LASPYTAAASAL 577
L SP TAAA+AL
Sbjct: 396 LGSPATAAATAL 407
[154][TOP]
>UniRef100_B5ICW8 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5ICW8_9EURY
Length = 419
Score = 119 bits (297), Expect = 2e-25
Identities = 79/197 (40%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK- 175
D+ T KYLE Y + SD A F EY F+V +LEP V+ PH+ DN E K
Sbjct: 227 DATTKKYLEEMGRGEKYREIKSDDDAWFEKEYEFNVDELEPTVSFPHTVDNTRTISEAKK 286
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
+++I++VYIG+CT G+ ED AAK+ G KV T L+ PA+++V++
Sbjct: 287 MNIRIDQVYIGTCTNGRIEDLRVAAKIL---DGNKVNKKTRLIVIPASRRVYIQALK--- 340
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F EAG SP CG C+G K A + + +ST NRNF GRMG+
Sbjct: 341 -----EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNP 391
Query: 527 EGEIYLASPYTAAASAL 577
EIYL SP TAAA+A+
Sbjct: 392 NAEIYLGSPATAAATAI 408
[155][TOP]
>UniRef100_A1RVH3 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
islandicum DSM 4184 RepID=LEUC_PYRIL
Length = 414
Score = 119 bits (297), Expect = 2e-25
Identities = 73/192 (38%), Positives = 107/192 (55%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL+ + V Y+ Q R++ +Y +++KLEPLVA P+S DN RE + V
Sbjct: 227 DVVTVDYLQRERGVSYKPP-DLQPGRYVDKYVVELSKLEPLVAAPYSVDNVKAVREVEGV 285
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++V+IGSCT G+ DF AA++ +VK +PA+ ++ L
Sbjct: 286 EVDQVFIGSCTNGRLSDFEIAARILRRG---RVKSRCIAIPASYTIFRKALELGY----- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
I +AGC +CG CLGG + +V VST+NRNF GRMGH + ++Y
Sbjct: 338 ---IDILTKAGC-VVTYGTCGPCLGG---HFGVAGPGEVVVSTSNRNFKGRMGHPDSKVY 390
Query: 542 LASPYTAAASAL 577
LA+P TAAA+AL
Sbjct: 391 LANPATAAAAAL 402
[156][TOP]
>UniRef100_B1C4Q4 Putative uncharacterized protein n=1 Tax=Clostridium spiroforme DSM
1552 RepID=B1C4Q4_9FIRM
Length = 424
Score = 118 bits (296), Expect = 3e-25
Identities = 80/197 (40%), Positives = 107/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y+E + Y+ +D+ A + D++K+ P VA PH P N E + +
Sbjct: 230 DDQTIAYMEEHSKKDYKVYTADEDAEYERVIEIDLSKVRPTVAFPHLPGNGHTIDEIEAM 289
Query: 182 K---INRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPV 346
+ I++V IGSCT G+ D AA + GKKV V +VPATQK+++ V
Sbjct: 290 EPIYIDQVVIGSCTNGRISDLRKAAAILK---GKKVARNVRVMVVPATQKIFLQCI---V 343
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
G ++IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG
Sbjct: 344 EG-----LAEIFVEAGCAFN-TPSCGPCMGGHMGVMAKGEK---CVSTTNRNFVGRMGDT 394
Query: 527 EGEIYLASPYTAAASAL 577
E IYLASP AAASA+
Sbjct: 395 EALIYLASPEVAAASAI 411
[157][TOP]
>UniRef100_B5IBC4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBC4_9EURY
Length = 419
Score = 118 bits (296), Expect = 3e-25
Identities = 79/197 (40%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK- 175
D+ T KYLE Y + SD A F EY F+V +LEP V+ PH+ DN E K
Sbjct: 227 DATTKKYLEEMGRGDKYREIKSDDDAWFEKEYEFNVDELEPTVSFPHTVDNTRTISEAKK 286
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
+++I++VYIG+CT G+ ED AAK+ G KV T L+ PA+++V++
Sbjct: 287 MNIRIDQVYIGTCTNGRIEDLRVAAKIL---DGNKVNKKTRLIVIPASRRVYIQALK--- 340
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F EAG SP CG C+G K A + + +ST NRNF GRMG+
Sbjct: 341 -----EGLLEKFVEAGAAIE-SPGCGPCVGIHKGVLA---DGERVLSTQNRNFKGRMGNP 391
Query: 527 EGEIYLASPYTAAASAL 577
EIYL SP TAAA+A+
Sbjct: 392 NAEIYLGSPATAAATAI 408
[158][TOP]
>UniRef100_B2UYH6 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum E3 str. Alaska E43 RepID=LEUC_CLOBA
Length = 419
Score = 118 bits (296), Expect = 3e-25
Identities = 74/194 (38%), Positives = 102/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ T ++ +D+ A + D++ L+P V+ PH PDN V
Sbjct: 231 DDKTVEYLKEHTEKEWKIYEADEDAEYDEVIEIDLSTLKPTVSFPHLPDNTRTIDNANRV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D A + GKKVK + ++P TQK+++ +
Sbjct: 291 NIDQVVIGSCTNGRISDLRIARGILK---GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ EAG ++P+CG CLGG A+ CVSTTNRNF GRMGH E E
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAKGER---CVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASAL
Sbjct: 396 VYLASPAVAAASAL 409
[159][TOP]
>UniRef100_Q0QLE2 2,3-dimethylmalate dehydratase large subunit n=1 Tax=Eubacterium
barkeri RepID=Q0QLE2_EUBBA
Length = 420
Score = 118 bits (295), Expect = 4e-25
Identities = 78/195 (40%), Positives = 107/195 (54%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T Y+E S Y+ +D A + + D+++L+ VA PH P+N ++
Sbjct: 231 DDQTISYMEEHGSGDYKVYAADADAVYEKTFDIDLSQLKSTVAFPHLPENTKTVDAIEEP 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
V I++V IGSCT G+ ED AA + GK VK V ++PAT K+++D
Sbjct: 291 VTIDQVVIGSCTNGRFEDLKRAADILR---GKHVKKGVRMLVIPATHKIYLDAMEAGY-- 345
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ F EAG T ++P+CG CLGG A E + CVSTTNRNF GRMGH +
Sbjct: 346 ------LREFIEAGA-TISTPTCGPCLGGYMGILA---EGERCVSTTNRNFVGRMGHVDS 395
Query: 533 EIYLASPYTAAASAL 577
E+YLASP AAASA+
Sbjct: 396 EVYLASPEVAAASAI 410
[160][TOP]
>UniRef100_C0C2K0 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0C2K0_9CLOT
Length = 417
Score = 118 bits (295), Expect = 4e-25
Identities = 75/193 (38%), Positives = 98/193 (50%), Gaps = 2/193 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T YL+ YE SD A F Y+F +L P VA PH D A +DV
Sbjct: 230 DDITEAYLDSIGVKDYEPYQSDADASFYRTYQFRAEELRPQVACPHEVDRVTEADNVRDV 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI + Y+GSCTGG+ D AA GKKV V + PA++ +W + +
Sbjct: 290 KIQQAYLGSCTGGRLHDLKTAAAYL---KGKKVAPGVRLLISPASRSIWRE--------A 338
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
G I EAG +P+CG C+G A + C+S++NRNF GRMG +EG+
Sbjct: 339 GRLGYLDILAEAG-GVIMAPTCGVCVGLHSGLIA---AGETCISSSNRNFLGRMGSKEGQ 394
Query: 536 IYLASPYTAAASA 574
IYL SP T AASA
Sbjct: 395 IYLGSPLTVAASA 407
[161][TOP]
>UniRef100_A6BFK8 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
13814 RepID=A6BFK8_9FIRM
Length = 424
Score = 118 bits (295), Expect = 4e-25
Identities = 77/195 (39%), Positives = 103/195 (52%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T +YL+ T Y+ +D A + S D++++ P VA PH P N E +
Sbjct: 230 DEKTEEYLKEHTKKEYKVYEADGDAEYESVVEIDLSEVRPTVAFPHLPGNAKTIDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPG 352
+KI++V IGSCT G+ ED AA + L V +VPATQK++
Sbjct: 290 EPIKIDQVVIGSCTNGRMEDMRKAAAI-LQGHTVHPDVRVMVVPATQKIYKQCIR----- 343
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 344 ---EGLLEIFVDAGCAVN-TPSCGPCMGGHMGVMAAGEK---CVSTTNRNFVGRMGHVDS 396
Query: 533 EIYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 397 LIYLASPEVAAASAI 411
[162][TOP]
>UniRef100_A1HRB1 3-isopropylmalate dehydratase n=1 Tax=Thermosinus carboxydivorans
Nor1 RepID=A1HRB1_9FIRM
Length = 417
Score = 118 bits (295), Expect = 4e-25
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +YL+ K YE ++D ++ +E+ FDV+ L+P VA PHS DN E
Sbjct: 227 DEITLEYLKDKVKGDYEIFHTDPGYQYAAEHTFDVSGLKPQVAAPHSVDNVHDITEYIGR 286
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPT--FLVPATQKVWMDVYSLPVPGS 355
+ + ++G+CTGG+ +D AAK+ GKKV T +VPA++ V+++
Sbjct: 287 PVQQAFLGTCTGGRVQDLAVAAKILK---GKKVHPRTRFIVVPASKAVFLEAME------ 337
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
K Q EAG T +P C ACLG + A + C++ ++RNFPGRMGH + E
Sbjct: 338 --KGYIQTLVEAGA-TFVTPGCAACLGTHQGMLAA---GETCITASSRNFPGRMGHTKAE 391
Query: 536 IYLASPYTAAASAL 577
I++ SP AA+AL
Sbjct: 392 IFIGSPAAVAAAAL 405
[163][TOP]
>UniRef100_B0K0Y2 3-isopropylmalate dehydratase large subunit n=4
Tax=Thermoanaerobacter RepID=LEUC_THEPX
Length = 418
Score = 118 bits (295), Expect = 4e-25
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++G+ Y+ D+ A + Y ++ ++ P VA PH P+N E V
Sbjct: 229 DEITEAYVKGRAKREYKVFERDEDAEYSEVYEINLDEIRPQVAFPHLPENTRSIDEVGKV 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D A K+ GKKV V + PATQ+++++
Sbjct: 289 KIDQVVIGSCTNGRLSDMEIAYKIL---KGKKVHPDVRLLIFPATQEIYLECVK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG AR + ++TTNRNF GRMGH E E
Sbjct: 340 --RGYIEEFIKAGA-AVSTPTCGPCLGGHMGILAR---GERALATTNRNFVGRMGHPESE 393
Query: 536 IYLASPYTAAASAL 577
+YL+SP AAASA+
Sbjct: 394 VYLSSPAVAAASAI 407
[164][TOP]
>UniRef100_B2V844 3-isopropylmalate dehydratase large subunit n=1
Tax=Sulfurihydrogenibium sp. YO3AOP1 RepID=LEUC_SULSY
Length = 431
Score = 118 bits (295), Expect = 4e-25
Identities = 70/192 (36%), Positives = 105/192 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T ++ +T+ ++ SD A++ EY FD +K+EP+VA P P N E
Sbjct: 231 DEKTVDWVRKRTNREFKLYKSDPDAKYCCEYEFDASKIEPVVACPSLPSNVKPVSEVAGT 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++V+IGSCT G+ D AA + L S +V ++PA+ +++
Sbjct: 291 HIDQVFIGSCTNGRLSDLRIAAAI-LKSKKVHPEVRCIVIPASDQIYKQALH-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +I +AGC S +CG CLGG A E +VC+ST+NRNF GRMGH + ++Y
Sbjct: 342 EGIIEILADAGCLISTS-TCGPCLGGHMGILA---EGEVCLSTSNRNFVGRMGHPKSQVY 397
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 398 LSSPAVAAASAV 409
[165][TOP]
>UniRef100_Q1AVC5 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Rubrobacter
xylanophilus DSM 9941 RepID=LEUC2_RUBXD
Length = 424
Score = 118 bits (295), Expect = 4e-25
Identities = 71/192 (36%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT +YL+ + + SD A ++ + + D+ LEPLVA PHSP N E +
Sbjct: 230 DEVTARYLDRRADREWHPERSDPDASYVRKVKIDLNSLEPLVALPHSPGNVVAVSEARGT 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++VYIG+C+ G D A++ L V +VPA+QKV+ S
Sbjct: 290 KIDQVYIGNCSNGTITDLRQTAEI-LRGNRVHPDVRAIIVPASQKVYRQAIS-------- 340
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +F EAG ++P+CGAC GG A E + ++TTNRNF GRMG E+
Sbjct: 341 EGLIDVFVEAGA-VVSTPTCGACFGGHMGVLA---EGERAITTTNRNFKGRMGSPLAEVC 396
Query: 542 LASPYTAAASAL 577
LA+ Y AAA+A+
Sbjct: 397 LANAYVAAAAAV 408
[166][TOP]
>UniRef100_C6PJB4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermoanaerobacter italicus Ab9 RepID=C6PJB4_9THEO
Length = 418
Score = 117 bits (294), Expect = 5e-25
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++G+ Y+ D+ A + Y ++ ++ P VA PH P+N E V
Sbjct: 229 DEITEAYVKGRAKREYKVFERDEDAEYSEVYEINLDEIRPQVAFPHLPENTRSIDEVGKV 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D A K+ GKKV V + PATQ+++++
Sbjct: 289 KIDQVVIGSCTNGRLSDMEIAYKIL---KGKKVHPDVRLLIFPATQEIYLECVK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG AR + ++TTNRNF GRMGH E E
Sbjct: 340 --RGYIEEFIKAGA-AISTPTCGPCLGGHMGILAR---GERALATTNRNFVGRMGHPESE 393
Query: 536 IYLASPYTAAASAL 577
+YL+SP AAASA+
Sbjct: 394 VYLSSPAVAAASAI 407
[167][TOP]
>UniRef100_C5UT24 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
botulinum E1 str. 'BoNT E Beluga' RepID=C5UT24_CLOBO
Length = 419
Score = 117 bits (294), Expect = 5e-25
Identities = 74/194 (38%), Positives = 101/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T KYL+ T ++ +D+ A + ++ L P V+ PH PDN V
Sbjct: 231 DNKTVKYLKEHTVKEWKVYKADEDAEYDEVIEIELNTLRPTVSFPHLPDNTRTIDNANGV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D A + GKKVK + ++P TQK+++ +
Sbjct: 291 DIDQVVIGSCTNGRISDLRIARDILK---GKKVKKGIRCIVIPGTQKIYLQALEEGI--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ EAG ++P+CG CLGG A+ CVSTTNRNF GRMGH E E
Sbjct: 345 -----IKDLIEAGA-VVSTPTCGPCLGGHMGILAKGER---CVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASAL
Sbjct: 396 VYLASPAVAAASAL 409
[168][TOP]
>UniRef100_B1C9W1 Putative uncharacterized protein n=1 Tax=Anaerofustis
stercorihominis DSM 17244 RepID=B1C9W1_9FIRM
Length = 424
Score = 117 bits (294), Expect = 5e-25
Identities = 74/198 (37%), Positives = 108/198 (54%), Gaps = 6/198 (3%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y + ++ +E +D+ A++ D++KL P V+ PH P+N E V
Sbjct: 231 DDKTIEYAKEHSTKTFEVFEADEDAQYDEVIEIDLSKLRPTVSFPHLPENTKTVDEAGKV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSL----P 343
I++ IGSCT G+ ED AA + GK+V KV T ++PATQK+++D L
Sbjct: 291 YIDQAVIGSCTNGRLEDIKMAADIL---RGKQVDKKVRTIVIPATQKIYLDSIKLGYVED 347
Query: 344 VPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGH 523
+ +G IF ++P+CG CLGG A + +STTNRNF GRMGH
Sbjct: 348 IVNAGA-----IF--------STPTCGPCLGGHMGILA---AGEKAISTTNRNFVGRMGH 391
Query: 524 REGEIYLASPYTAAASAL 577
+ E+YL+SP AAASA+
Sbjct: 392 VDSEVYLSSPAVAAASAI 409
[169][TOP]
>UniRef100_Q0W1Q4 3-isopropylmalate dehydratase, large subunit n=1 Tax=uncultured
methanogenic archaeon RC-I RepID=Q0W1Q4_UNCMA
Length = 414
Score = 117 bits (294), Expect = 5e-25
Identities = 71/192 (36%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ +L+G+ Y VY+ + A + E DV+KL P V+ P DN E +
Sbjct: 228 DEKTFAFLKGRAVEEYRPVYASRDAVYCDELHLDVSKLHPQVSCPPDVDNVKDVGEVEGT 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V IGSCT G+ ED AA + G+KV+ T ++PA++ V +D V
Sbjct: 288 HVDQVLIGSCTNGRYEDLAGAAAIL---KGRKVRCRTLIIPASRSVMLDAVQTGVAAD-- 342
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
AG T +P CG CLGG A E + C++TTNRNF GRMG + ++Y
Sbjct: 343 ------LLAAGA-TICNPGCGPCLGGHMGVLA---EGEACLATTNRNFRGRMG-KGADVY 391
Query: 542 LASPYTAAASAL 577
L SP TAAA+A+
Sbjct: 392 LGSPLTAAATAI 403
[170][TOP]
>UniRef100_A2SR25 3-isopropylmalate dehydratase, large subunit n=1
Tax=Methanocorpusculum labreanum Z RepID=A2SR25_METLZ
Length = 392
Score = 117 bits (294), Expect = 5e-25
Identities = 72/192 (37%), Positives = 104/192 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T++Y+ G+T V S+ SD+ A F +D+ K+ P +A PH+ DN E
Sbjct: 204 DEKTWEYMRGRTEVTPFSLASDEDAVFFETRNYDIAKINPKIAVPHNVDNVVDVTEVAGK 263
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V+IGSCT G+ EDF AA+V L V +VPA++ +M V +
Sbjct: 264 PVDQVFIGSCTNGRYEDFAEAAEV-LGDNVFSEDVRVIMVPASKAEYMKVLKAGL----- 317
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F EAG A P CG C+GG + + +V +ST+NRNF GR G E +Y
Sbjct: 318 ---IEKFVEAGALVEA-PCCGPCMGG---AFGLLAPGEVSLSTSNRNFRGRQGSTESFVY 370
Query: 542 LASPYTAAASAL 577
L+SP TAAASA+
Sbjct: 371 LSSPATAAASAI 382
[171][TOP]
>UniRef100_Q9UZ07 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
abyssi RepID=LEUC1_PYRAB
Length = 423
Score = 117 bits (294), Expect = 5e-25
Identities = 74/195 (37%), Positives = 108/195 (55%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRA-LARECK- 175
D T Y++ + ++ SD+ A++ +DVT EP+VA PH P+N +++ K
Sbjct: 231 DKKTLDYVKERAKRKFKVYKSDEDAKYYKVIEYDVTNWEPVVAFPHLPENTVPISKAAKM 290
Query: 176 DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK-VPTFLVPATQKVWMDVYSLPVPG 352
++KI++V+IGSCT G+ ED AA++ G K K V ++P + V+
Sbjct: 291 NIKIDQVFIGSCTNGRIEDLRMAAEIL--EGQKVAKWVRLIVIPCSPTVYWKALK----- 343
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ +IF EAG P+CG CLGG A + VSTTNRNF GRMGH +
Sbjct: 344 ---EGLIEIFLEAGA-VIGPPTCGPCLGGHMGVLA---SGERAVSTTNRNFVGRMGHPKS 396
Query: 533 EIYLASPYTAAASAL 577
E+YLA+PY AAASA+
Sbjct: 397 EVYLANPYVAAASAV 411
[172][TOP]
>UniRef100_B9KB94 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KB94_THENN
Length = 417
Score = 117 bits (293), Expect = 6e-25
Identities = 73/194 (37%), Positives = 105/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D T Y E + + E +Y D+ A ++ E ++++LEP VA P P N E +
Sbjct: 228 DETTIAY-EKERGIEVEEMYPDEDAEYVKEVEMNLSELEPQVAYPFLPSNTKDISESEKE 286
Query: 179 -VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGS 355
+KI++V IGSCT G+ ED AA++ L V ++P +QKV+
Sbjct: 287 RIKIDQVVIGSCTNGRIEDLRLAAQI-LKGRTVSPNVRCIIIPGSQKVYKQALK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AGC ++P+CG CLGG A E ++ VSTTNRNF GRMGH +
Sbjct: 340 --EGLIDIFLDAGCAV-STPTCGPCLGGHMGVLA---EGEIAVSTTNRNFVGRMGHPNSK 393
Query: 536 IYLASPYTAAASAL 577
++LASP AAASA+
Sbjct: 394 VFLASPAVAAASAV 407
[173][TOP]
>UniRef100_C0WAT0 3-isopropylmalate dehydratase n=1 Tax=Acidaminococcus sp. D21
RepID=C0WAT0_9FIRM
Length = 418
Score = 117 bits (293), Expect = 6e-25
Identities = 75/192 (39%), Positives = 100/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y +G+ YE V +D A + D+T L P+VA PH P N D+
Sbjct: 230 DEKTKAYEQGRVE-DYEIVTADSDAVYKRTVTIDLTALTPVVAFPHLPGNTKAIGTFGDI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++V IGSCT G+ ED AAK+ L V ++P +Q+V+ +
Sbjct: 289 PIDQVVIGSCTNGRLEDLAIAAKI-LEGRTVHPDVRCIVIPGSQEVYKEAMK-------- 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
K F +AGC ++P+CG CLGG A + CVSTTNRNF GRMGH + E+Y
Sbjct: 340 KGYIDTFIDAGC-VVSTPTCGPCLGGYMGILA---AGERCVSTTNRNFRGRMGHVDSEVY 395
Query: 542 LASPYTAAASAL 577
LA P AAASA+
Sbjct: 396 LAGPQVAAASAI 407
[174][TOP]
>UniRef100_B0G7V2 Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC
27755 RepID=B0G7V2_9FIRM
Length = 425
Score = 117 bits (293), Expect = 6e-25
Identities = 77/197 (39%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T +YL T Y +D+ A + D+ ++ P VA PH P N E +
Sbjct: 230 DDKTIQYLNEHTKKEYTVYEADEDAEYEQVVEIDLAEVRPTVAFPHLPGNAKTIDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPV 346
+KI++V IGSCT G+ ED AA + G KV V ++PATQK++
Sbjct: 290 EPIKIDQVVIGSCTNGRMEDMRKAAAILK---GHKVHEDVRVMVIPATQKIYKQCIH--- 343
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH
Sbjct: 344 -----EGLMDIFVDAGCAVN-TPSCGPCMGGHMGVMAAGEK---CVSTTNRNFVGRMGHV 394
Query: 527 EGEIYLASPYTAAASAL 577
+ IYLASP AAASA+
Sbjct: 395 DSLIYLASPEVAAASAI 411
[175][TOP]
>UniRef100_A1HLS2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HLS2_9FIRM
Length = 420
Score = 117 bits (293), Expect = 6e-25
Identities = 72/194 (37%), Positives = 105/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL + YE+V D A ++ ++ LEP+VA PH P+N A + +D+
Sbjct: 230 DDATIRYLSTRVERDYEAVSPDADASYVRTVVINLDDLEPVVALPHLPENVRPAAQVRDI 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ ED AA + GK V +V ++P +Q V+++
Sbjct: 290 AIDQVVIGSCTNGRLEDLAQAAAIL---EGKTVHPRVRAIVIPGSQAVYLEAMQ------ 340
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F AG ++P+CG CLGG A + V+TTNRNF GRMGH + E
Sbjct: 341 --RGYIETFIRAGA-VVSTPTCGPCLGGYMGILA---AGERAVATTNRNFRGRMGHVDSE 394
Query: 536 IYLASPYTAAASAL 577
+YLA P AAASA+
Sbjct: 395 VYLAGPAVAAASAV 408
[176][TOP]
>UniRef100_A9AAG0 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C6 RepID=A9AAG0_METM6
Length = 424
Score = 117 bits (293), Expect = 6e-25
Identities = 68/197 (34%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEG-----KTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAR 166
D T Y++ T+ P+E + D+ A F ++ +V LEP++A PH+ DN R
Sbjct: 230 DDKTINYVKNAMETNNTAKPFEFILGDKNAEFEEKFEIEVDNLEPVMACPHNVDNVKAVR 289
Query: 167 ECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPV 346
E I++V+IGSCT G+ ED AA V GG + + PA++ V ++
Sbjct: 290 EVAGTPIDQVFIGSCTNGRIEDLRAALNVIEKHGGISKDIRVVVTPASRSVMLEAID--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ + F + GC +PSC AC+G Y + +V ++T+NRNF GR G
Sbjct: 347 -----EGLIKKFYQYGC-VVTNPSCSACMGA---LYGLLGSGEVGIATSNRNFRGREGSL 397
Query: 527 EGEIYLASPYTAAASAL 577
E ++YLASP TAAA A+
Sbjct: 398 ESDVYLASPITAAACAV 414
[177][TOP]
>UniRef100_C5STD4 3-isopropylmalate dehydratase n=1 Tax=Sulfolobus solfataricus 98/2
RepID=C5STD4_SULSO
Length = 415
Score = 117 bits (293), Expect = 6e-25
Identities = 71/192 (36%), Positives = 101/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ E V D A+++ EY + K+EPLVA PHS DN + E +
Sbjct: 229 DQETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDKMEPLVAAPHSVDNVKVVNELEGT 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ +
Sbjct: 289 PVDQVYIGSCTNGRLSDFEIAAKIM---KGKKVKSRCIAIPASYRMFKEALE-------- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ Q +AGC +CG CLGG + + VST++RNF GRMG E +IY
Sbjct: 338 RGYIQTLVDAGCIVTYG-TCGPCLGG---HFGIAGPGENIVSTSSRNFKGRMGSNEAKIY 393
Query: 542 LASPYTAAASAL 577
L+ P AA SAL
Sbjct: 394 LSGPAVAAISAL 405
[178][TOP]
>UniRef100_Q3Z894 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides ethenogenes 195 RepID=Q3Z894_DEHE1
Length = 416
Score = 117 bits (292), Expect = 8e-25
Identities = 70/194 (36%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+ + Y +D A + Y FD++KLEP V+ PHSP N + +
Sbjct: 228 DEKTLEYVTPRAKRQYTVYDNDADASYAKTYNFDISKLEPQVSLPHSPANARPISQIGKI 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
K+++V IGSCT G+ ED +AK+ G KV + T ++P +Q+V++D
Sbjct: 288 KVDQVIIGSCTNGRLEDLAISAKLL---EGNKVSPDLRTIVIPGSQQVYLDALKAGY--- 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + E
Sbjct: 342 -----IETFINAGV-AVSTPTCGPCLGGHMGILA---AGERCLATTNRNFVGRMGSPKSE 392
Query: 536 IYLASPYTAAASAL 577
+YLA P AAA+A+
Sbjct: 393 VYLAGPAVAAATAI 406
[179][TOP]
>UniRef100_C8SB74 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SB74_FERPL
Length = 419
Score = 117 bits (292), Expect = 8e-25
Identities = 82/196 (41%), Positives = 108/196 (55%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYES---VYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC 172
D VT YL+ V YE +YSD+ A + E DV+ LEP VA PHS DN E
Sbjct: 230 DKVTEDYLKS-IGVDYEIPEWLYSDEDA-YWKEVSLDVSNLEPQVACPHSVDNVKPVSEV 287
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK-VPTFLVPATQKVWMDVYSLPVP 349
+ VKI++V+IGSCT G+ ED AA++ G K K V ++PA++ +
Sbjct: 288 EGVKIDQVFIGSCTNGRYEDLKVAAEIL--KGEKVAKGVRLIVIPASRSHYKRALK---- 341
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
+ IF EAG PSCG C+GG ++ + +V +ST+NRNF GR G E
Sbjct: 342 ----EGLIDIFVEAGA-IVEFPSCGPCMGG---SFGLIASKEVSLSTSNRNFIGRQGSPE 393
Query: 530 GEIYLASPYTAAASAL 577
GEIYL SP TAAASA+
Sbjct: 394 GEIYLCSPATAAASAI 409
[180][TOP]
>UniRef100_B1YD98 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
neutrophilus V24Sta RepID=LEUC_THENV
Length = 415
Score = 117 bits (292), Expect = 8e-25
Identities = 71/192 (36%), Positives = 106/192 (55%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL+ + V Y+ S + R++ Y ++ +LEPLVA P+S DN ARE + V
Sbjct: 227 DEVTADYLQRERGVSYKPP-SLEPGRYVDRYEVELQRLEPLVAAPYSVDNVKAAREVEGV 285
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++V+IGSCT G+ DF AA+V + K +PA+ V+ L
Sbjct: 286 EVDQVFIGSCTNGRLSDFEVAARVLKRG---RAKARCIAIPASYAVFRRAMELGY----- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +AGC +CG CLGG + +V V+T+NRNF GR+GH + ++Y
Sbjct: 338 ---IDVLTKAGC-VVTYGTCGPCLGG---HFGVAGPGEVVVTTSNRNFKGRVGHPDSKVY 390
Query: 542 LASPYTAAASAL 577
LA+P TAAA+AL
Sbjct: 391 LANPATAAAAAL 402
[181][TOP]
>UniRef100_B2TIQ9 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum B str. Eklund 17B RepID=LEUC_CLOBB
Length = 419
Score = 117 bits (292), Expect = 8e-25
Identities = 73/194 (37%), Positives = 100/194 (51%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL+ T +E +D+ A + ++ L P V+ PH PDN D+
Sbjct: 231 DDKTVEYLKEHTKKEWEVYKADEDAEYDEVIEIELNTLRPTVSFPHLPDNTRTIDNVGDI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I++V IGSCT G+ D A + GKKVK + ++P TQ +++ +
Sbjct: 291 DIDQVVIGSCTNGRISDLRIARDILK---GKKVKKGIRCIVIPGTQNIYLQALEEGI--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ EAG ++P+CG CLGG A+ CVSTTNRNF GRMGH E E
Sbjct: 345 -----IKDLIEAGV-VVSTPTCGPCLGGHMGILAKGER---CVSTTNRNFVGRMGHVESE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASAL
Sbjct: 396 VYLASPAVAAASAL 409
[182][TOP]
>UniRef100_C4V4K3 3-isopropylmalate dehydratase n=1 Tax=Selenomonas flueggei ATCC
43531 RepID=C4V4K3_9FIRM
Length = 420
Score = 116 bits (291), Expect = 1e-24
Identities = 74/195 (37%), Positives = 105/195 (53%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KD 178
D V Y+EG+ + P+ V +D AR+ D++ L P+V+ PH P+N +
Sbjct: 230 DDVCRAYVEGRMTKPFAPVAADADARYAQTVEIDLSALRPVVSFPHLPENTKRVMDIGAP 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPG 352
+ I++V IGSCT G+ ED AA + G KV +V ++P + V+ +
Sbjct: 290 IAIDQVVIGSCTNGRLEDMEIAASILK---GHKVHERVRCIVIPGSPYVYEE-------- 338
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
S + IF EAG ++P+CG CLGG A CVSTTNRNF GRMGH +
Sbjct: 339 SMKRGYLAIFMEAGAAI-STPTCGPCLGGYMGILAAGER---CVSTTNRNFRGRMGHVDS 394
Query: 533 EIYLASPYTAAASAL 577
E+YLA P+ AAASA+
Sbjct: 395 EVYLAGPHVAAASAI 409
[183][TOP]
>UniRef100_B9D2G7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
rectus RM3267 RepID=B9D2G7_WOLRE
Length = 424
Score = 116 bits (291), Expect = 1e-24
Identities = 77/197 (39%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV-YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-- 172
D T ++L+GK + YSD+ A + + DV+KL+P++A P P N RE
Sbjct: 233 DETTKEFLKGKNLRAEPKLHYSDEGANYEQILQIDVSKLDPVIAYPFLPSNGKSVREAVK 292
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
D+ I++ +IGSCT G+ D AA++ G+KV T L+ PATQK+ +
Sbjct: 293 DDIAIDQAFIGSCTNGRLSDLRIAAEILK---GRKVARKTRLIITPATQKIALQAQK--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ IF EAG ++P+CGACLGG + + CVSTTNRNF GRMG R
Sbjct: 347 -----EGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDR 397
Query: 527 EGEIYLASPYTAAASAL 577
E+YLA+ AAASA+
Sbjct: 398 TSEVYLANSAVAAASAV 414
[184][TOP]
>UniRef100_A8ABG2 3-isopropylmalate dehydratase n=1 Tax=Ignicoccus hospitalis KIN4/I
RepID=A8ABG2_IGNH4
Length = 429
Score = 116 bits (291), Expect = 1e-24
Identities = 71/196 (36%), Positives = 110/196 (56%), Gaps = 4/196 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKT-SVPY-ESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK 175
D +++EG+ VP E + D A + E+ +D++++EP+VAKP+SP N E +
Sbjct: 229 DEEVMRFVEGRARGVPKPELTFPDPGAHYKDEFTYDLSEIEPMVAKPYSPANSVPVSEVE 288
Query: 176 DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPT--FLVPATQKVWMDVYSLPVP 349
+++++V+IGSCT G+ ED AA++ GKKV T ++ A++ V++
Sbjct: 289 GIEVDQVFIGSCTNGRLEDVAVAARIL---KGKKVAPNTRCIVITASRNVYLQALK---- 341
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHRE 529
K + EAGC +CG C+G Y + +V + TTNRNF GR GHR
Sbjct: 342 ----KGYVDVLTEAGC-LVTFGTCGPCVGA---HYGVLGPNEVGLFTTNRNFRGRSGHRT 393
Query: 530 GEIYLASPYTAAASAL 577
++YLASP TAAASA+
Sbjct: 394 SKVYLASPATAAASAV 409
[185][TOP]
>UniRef100_UPI0001979722 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
cinaedi CCUG 18818 RepID=UPI0001979722
Length = 420
Score = 116 bits (290), Expect = 1e-24
Identities = 66/192 (34%), Positives = 104/192 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y +G+TS + +D+ A + + ++ ++ VA PH P+N + ++
Sbjct: 231 DDITIEYAKGRTSKEFRIYKADEDAEYEEVFDIELDSIDHTVAFPHLPENTKEREQWGEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++V IGSCT G+ D AA + K ++PATQ ++++ +
Sbjct: 291 KIDQVVIGSCTNGRLSDMEVAANILKDKTIAK-NTRCIIIPATQNIYLECIN-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ + F +AG ++P+CG CLGG A + CVSTTNRNF GRMGH E+Y
Sbjct: 342 RGYLETFIKAGA-VVSTPTCGPCLGGHMGILAANEK---CVSTTNRNFVGRMGHTTSEVY 397
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 398 LSSPEVAAASAV 409
[186][TOP]
>UniRef100_A5FR41 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. BAV1 RepID=A5FR41_DEHSB
Length = 416
Score = 116 bits (290), Expect = 1e-24
Identities = 68/192 (35%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+ + Y +D A + Y FD++KLEP V+ PHSP N + +
Sbjct: 228 DEKTLEYVTPRAKRQYTVYDNDADASYAKTYNFDISKLEPQVSLPHSPANARPVSQIGKI 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K+++V IGSCT G+ ED +AK+ L + T ++P +Q+V++D
Sbjct: 288 KVDQVIIGSCTNGRLEDLAVSAKL-LKGNVVHPDLRTIVIPGSQQVYLDALKAGY----- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + E+Y
Sbjct: 342 ---IETFINAGV-AVSTPTCGPCLGGHMGILA---AGERCLATTNRNFVGRMGSPKSEVY 394
Query: 542 LASPYTAAASAL 577
LA P AAA+A+
Sbjct: 395 LAGPAVAAATAI 406
[187][TOP]
>UniRef100_C6RH21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Campylobacter
showae RM3277 RepID=C6RH21_9PROT
Length = 424
Score = 116 bits (290), Expect = 1e-24
Identities = 77/197 (39%), Positives = 107/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV-YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-- 172
D T ++L+GK + YSD+ A + DV+KL+P++A P P N RE
Sbjct: 233 DETTKEFLKGKNLRAEPKLHYSDEGANYEQILEIDVSKLDPVIAYPFLPSNGKSVREAVR 292
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
D+ I++ +IGSCT G+ D AA++ G+KV T L+ PATQK+ +
Sbjct: 293 DDIAIDQAFIGSCTNGRLSDLRIAAEILK---GRKVARKTRLIITPATQKIALQAQK--- 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ IF EAG ++P+CGACLGG + + CVSTTNRNF GRMG R
Sbjct: 347 -----EGLMDIFAEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDR 397
Query: 527 EGEIYLASPYTAAASAL 577
E+YLA+ AAASA+
Sbjct: 398 TSEVYLANSAVAAASAV 414
[188][TOP]
>UniRef100_C3XG48 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
bilis ATCC 43879 RepID=C3XG48_9HELI
Length = 420
Score = 116 bits (290), Expect = 1e-24
Identities = 66/192 (34%), Positives = 104/192 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +Y +G+TS + +D+ A + + ++ ++ VA PH P+N + ++
Sbjct: 231 DDITIEYAKGRTSKEFRIYKADEDAEYEEVFDIELDSIDHTVAFPHLPENTKEREQWGEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++V IGSCT G+ D AA + K ++PATQ ++++ +
Sbjct: 291 KIDQVVIGSCTNGRLSDMEVAANILKDKTIAK-NTRCIIIPATQNIYLECIN-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ + F +AG ++P+CG CLGG A + CVSTTNRNF GRMGH E+Y
Sbjct: 342 RGYLETFIKAGA-VVSTPTCGPCLGGHMGILAANEK---CVSTTNRNFVGRMGHTTSEVY 397
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 398 LSSPEVAAASAV 409
[189][TOP]
>UniRef100_Q2NE97 LeuC1 n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE97_METST
Length = 418
Score = 116 bits (290), Expect = 1e-24
Identities = 72/194 (37%), Positives = 108/194 (55%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +YL+ +T+ Y +D+ A L DV+ LEP VA P+ DN A E +DV
Sbjct: 230 DKITDEYLKNRTTKQYTKFTTDKDAASLEVMDIDVSDLEPQVACPNYVDNVKPASEVEDV 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+I++V+IGSCT G+ +D AA+V G K+ V T ++PA++ ++
Sbjct: 290 EIDQVFIGSCTNGRLKDLEQAARVL---KGNKINPGVRTLVIPASRTIYKQALD------ 340
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG +P CG CLGG + + +V +ST+NRNF GR G EG+
Sbjct: 341 --EGLMDIFVDAGA-LICNPCCGPCLGGHVGV---IGDGEVSLSTSNRNFKGRQGSPEGK 394
Query: 536 IYLASPYTAAASAL 577
+YL+SP AA SA+
Sbjct: 395 VYLSSPIVAAESAI 408
[190][TOP]
>UniRef100_C7MMM0 3-isopropylmalate dehydratase, large subunit n=1
Tax=Cryptobacterium curtum DSM 15641 RepID=C7MMM0_CRYCD
Length = 423
Score = 115 bits (289), Expect = 2e-24
Identities = 74/194 (38%), Positives = 99/194 (51%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T YL+ +T PY D+ A + D + P VA PH P N E +DV
Sbjct: 234 DTTTRAYLDARTERPYTVYNPDEGAVYARTITIDAADIVPTVAFPHLPSNTRPVAEARDV 293
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++ IGSCT G+ ED AAA V G+ V +V ++PATQ V+
Sbjct: 294 AIDQAVIGSCTNGRIEDMRAAAHVL---NGRTVHPRVRCIVIPATQAVFKQCID------ 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + IF A C ++P+CG CLGG A + ++TTNRNF GRMG E
Sbjct: 345 --EGLTDIFVNAHC-VVSTPTCGPCLGGHMGVLA---PGERAIATTNRNFIGRMGDTTSE 398
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 399 VYLASPAVAAASAV 412
[191][TOP]
>UniRef100_Q4JC09 3-isopropylmalate dehydratase large subunit n=1 Tax=Sulfolobus
acidocaldarius RepID=LEUC_SULAC
Length = 414
Score = 115 bits (289), Expect = 2e-24
Identities = 67/192 (34%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ Y++ + V D A+++ EY D++KL+PLVA PHS DN E +
Sbjct: 228 DQETFNYIKTARGYEPQMVTPDSDAKYVDEYNIDLSKLDPLVAAPHSVDNVKSVNEVEGT 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V+IGSCT G+ D AAK+ GKKVK T ++PA+ +++ L
Sbjct: 288 PVDQVFIGSCTNGRISDLEMAAKIL---KGKKVKTRTIVIPASYQLFKKALELGY----- 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
Q +AG +CG CLGG + + +ST++RNF GRMG + ++Y
Sbjct: 340 ---VQTLADAGAIITYG-TCGPCLGG---HFGIAGPGETIISTSSRNFKGRMGSPDAKVY 392
Query: 542 LASPYTAAASAL 577
L+ P AAA+AL
Sbjct: 393 LSGPAVAAATAL 404
[192][TOP]
>UniRef100_A8MDY8 3-isopropylmalate dehydratase large subunit n=1 Tax=Caldivirga
maquilingensis IC-167 RepID=LEUC_CALMQ
Length = 415
Score = 115 bits (289), Expect = 2e-24
Identities = 71/192 (36%), Positives = 109/192 (56%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T YL + + + D A+++ EY ++ KLEPLVA PHS DN E + +
Sbjct: 228 DEETVSYLSRSRGINVKPITPDPDAKYVDEYTIELNKLEPLVAAPHSVDNVKPVSEVEGI 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++ V+IGSCT G+ D AAA++ L +G KVK ++PA++ D+++ +
Sbjct: 288 EVDYVFIGSCTNGRLSDLEAAARI-LKNG--KVKARCIVIPASR----DLFTKALDAGYV 340
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+T + +AGC +CG CLGG + + + VST +RNF GRMG EG++Y
Sbjct: 341 ETLT----KAGC-VVTYGTCGPCLGG---HFGVIGPGETAVSTGSRNFKGRMGSPEGKVY 392
Query: 542 LASPYTAAASAL 577
LA+ TAAA+AL
Sbjct: 393 LANAATAAATAL 404
[193][TOP]
>UniRef100_UPI000196B289 hypothetical protein CATMIT_00953 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196B289
Length = 425
Score = 115 bits (288), Expect = 2e-24
Identities = 77/197 (39%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D +YL+ Y+ +D+ A + D++ + P VA PH P N E +
Sbjct: 230 DEAAIEYLDKHAKRDYKIYEADKDAEYEEIVDVDLSAIRPTVAFPHLPGNAKTVDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPV 346
+ I++V IGSCT G+ ED AA + GKKV V +VPATQK+++ +
Sbjct: 290 DKIYIDQVVIGSCTNGRMEDLRKAAAILK---GKKVADNVRVMVVPATQKIYLQCILEGI 346
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ F EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG
Sbjct: 347 --------LETFVEAGCAVN-TPSCGPCMGGHMGVLAKGEK---CVSTTNRNFVGRMGDV 394
Query: 527 EGEIYLASPYTAAASAL 577
E IYLASP TAAASA+
Sbjct: 395 ESLIYLASPETAAASAI 411
[194][TOP]
>UniRef100_Q3ZXI5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. CBDB1 RepID=Q3ZXI5_DEHSC
Length = 416
Score = 115 bits (288), Expect = 2e-24
Identities = 67/192 (34%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+ + Y +D A + Y FD++K+EP V+ PHSP N + +
Sbjct: 228 DEKTLEYVTPRAKRQYTVYDNDADASYAKTYNFDISKIEPQVSLPHSPANARPVSQIGKI 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K+++V IGSCT G+ ED +AK+ L + T ++P +Q+V++D
Sbjct: 288 KVDQVIIGSCTNGRLEDLAVSAKL-LKGNVVHPDLRTIVIPGSQQVYLDALKAGY----- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + E+Y
Sbjct: 342 ---IETFINAGV-AVSTPTCGPCLGGHMGILA---AGERCLATTNRNFVGRMGSPKSEVY 394
Query: 542 LASPYTAAASAL 577
LA P AAA+A+
Sbjct: 395 LAGPAVAAATAI 406
[195][TOP]
>UniRef100_A8CP51 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. VS RepID=A8CP51_9CHLR
Length = 416
Score = 115 bits (288), Expect = 2e-24
Identities = 68/192 (35%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y+ + Y +D A + Y FD++KLEP V+ PHSP N + +
Sbjct: 228 DEKTLEYVTPRAKRQYTVYDNDADASYAKTYNFDISKLEPQVSLPHSPANARPISQIGKI 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
K+++V IGSCT G+ ED +AK+ L + T ++P +Q+V++D
Sbjct: 288 KVDQVIIGSCTNGRLEDLAISAKL-LEVNKVNPDLRTIVIPGSQQVYLDALKAGY----- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F AG ++P+CG CLGG A + C++TTNRNF GRMG + E+Y
Sbjct: 342 ---IETFINAGV-AVSTPTCGPCLGGHMGILA---AGERCLATTNRNFVGRMGSPKSEVY 394
Query: 542 LASPYTAAASAL 577
LA P AAA+A+
Sbjct: 395 LAGPAVAAATAI 406
[196][TOP]
>UniRef100_A7B6Z9 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
29149 RepID=A7B6Z9_RUMGN
Length = 425
Score = 115 bits (288), Expect = 2e-24
Identities = 75/195 (38%), Positives = 100/195 (51%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T YLE + Y+ +D+ A + D++++ P VA PH P N E +
Sbjct: 230 DEQTKAYLEEHSKKEYQIFEADEDADYEQVVTIDLSEVRPTVAFPHLPGNAKTIDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPG 352
+KI++V IGSCT G+ ED AA + L V ++PATQK++
Sbjct: 290 EPIKIDQVVIGSCTNGRMEDMRKAAAI-LKGHTVHPDVRVMVIPATQKIYKQCIK----- 343
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ IF +AGC +PSCG C+GG A CVSTTNRNF GRMGH +
Sbjct: 344 ---EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAAGER---CVSTTNRNFVGRMGHVDS 396
Query: 533 EIYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 397 LIYLASPEVAAASAI 411
[197][TOP]
>UniRef100_C4KKU6 3-isopropylmalate dehydratase n=1 Tax=Sulfolobus islandicus M.16.4
RepID=C4KKU6_SULIK
Length = 415
Score = 115 bits (288), Expect = 2e-24
Identities = 69/192 (35%), Positives = 101/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ E V D A+++ EY + ++EPLVA PHS DN + E +
Sbjct: 229 DQETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDEMEPLVAAPHSVDNVKVVNELEGT 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ +
Sbjct: 289 PVDQVYIGSCTNGRLSDFEIAAKIM---KGKKVKSRCIAIPASYRMFKEALE-------- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ Q +AGC +CG CLGG + + VST++RNF GRMG E ++Y
Sbjct: 338 RGYIQTLVDAGCIVTYG-TCGPCLGG---HFGIAGPGENIVSTSSRNFKGRMGSNEAKVY 393
Query: 542 LASPYTAAASAL 577
L+ P AA SAL
Sbjct: 394 LSGPAVAAISAL 405
[198][TOP]
>UniRef100_A6UPF6 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
vannielii SB RepID=A6UPF6_METVS
Length = 424
Score = 115 bits (288), Expect = 2e-24
Identities = 64/184 (34%), Positives = 98/184 (53%)
Frame = +2
Query: 26 EGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIG 205
+ T+ P++ + D+ A + ++ +V LEP++A PH+ DN RE I++V+IG
Sbjct: 243 KNNTARPFDIIIGDKNAEYEEKFEIEVNDLEPVMACPHNVDNVKTVREVSGTPIDQVFIG 302
Query: 206 SCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFE 385
SCT G+ ED AA V GG + + PA++ V + + Q F
Sbjct: 303 SCTNGRIEDLRAALNVIEKHGGISKDIRVIVTPASRSVMLKALD--------EGLIQKFY 354
Query: 386 EAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAA 565
+ GC +PSC AC+G Y + +V ++T+NRNF GR G E ++YLASP TAA
Sbjct: 355 KYGC-VVTNPSCSACMGA---LYGLLGPKEVGIATSNRNFRGREGSLESDVYLASPITAA 410
Query: 566 ASAL 577
A A+
Sbjct: 411 ACAV 414
[199][TOP]
>UniRef100_Q974R0 3-isopropylmalate dehydratase large subunit n=1 Tax=Sulfolobus
tokodaii RepID=LEUC_SULTO
Length = 415
Score = 115 bits (288), Expect = 2e-24
Identities = 70/192 (36%), Positives = 99/192 (51%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y++ V D+ A+++ EY D+ KLEPLVA PHS DN E + +
Sbjct: 228 DEETVNYIKTNRGYEPNIVRPDEGAKYVDEYTIDLGKLEPLVAAPHSVDNVKTVNEVEGL 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++V+IGSCT G+ DF AAK+ GK+VK +PA+ ++ L
Sbjct: 288 DVDQVFIGSCTNGRISDFEIAAKIL---KGKRVKSRCIAIPASYDLFKKAMELGY----- 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ AGC +CG CLGG + + VST++RNF GRMG + ++Y
Sbjct: 340 ---IETLVNAGCIVTYG-TCGPCLGG---HFGVAGPGETIVSTSSRNFKGRMGSNDSKVY 392
Query: 542 LASPYTAAASAL 577
LA P AAASAL
Sbjct: 393 LAGPAVAAASAL 404
[200][TOP]
>UniRef100_Q97VY2 3-isopropylmalate dehydratase large subunit n=3 Tax=Sulfolobus
RepID=LEUC_SULSO
Length = 416
Score = 115 bits (288), Expect = 2e-24
Identities = 69/192 (35%), Positives = 101/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ E V D A+++ EY + ++EPLVA PHS DN + E +
Sbjct: 230 DQETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDEMEPLVAAPHSVDNVKVVNELEGT 289
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ +
Sbjct: 290 PVDQVYIGSCTNGRLSDFEIAAKIM---KGKKVKSRCIAIPASYRMFKEALE-------- 338
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ Q +AGC +CG CLGG + + VST++RNF GRMG E ++Y
Sbjct: 339 RGYIQTLVDAGCIVTYG-TCGPCLGG---HFGIAGPGENIVSTSSRNFKGRMGSNEAKVY 394
Query: 542 LASPYTAAASAL 577
L+ P AA SAL
Sbjct: 395 LSGPAVAAISAL 406
[201][TOP]
>UniRef100_A4WMI6 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
arsenaticum DSM 13514 RepID=LEUC_PYRAR
Length = 415
Score = 115 bits (288), Expect = 2e-24
Identities = 70/191 (36%), Positives = 105/191 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+VT +YL+ V Y S + + +Y ++ +LEPLVA PHS DN RE + V
Sbjct: 227 DAVTAEYLKTARGVDYTPP-SLEPGNYADKYTVELGRLEPLVAAPHSVDNVKTVREVEGV 285
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++V+IGSCT G+ D AA++ G++VK +PA+ +V+ L
Sbjct: 286 EVDQVFIGSCTNGRLRDIATAARIL---KGRRVKTRCIAIPASYEVFKTAMKLGY----- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ EAGC +CG CLGG + +V ++T+NRNF GR+GH E +IY
Sbjct: 338 ---IDVLTEAGC-VVTYGTCGPCLGG---HFGVAGPGEVHLTTSNRNFKGRVGHPEAKIY 390
Query: 542 LASPYTAAASA 574
LA+P AAA+A
Sbjct: 391 LANPAVAAATA 401
[202][TOP]
>UniRef100_Q58409 Homoaconitase large subunit n=1 Tax=Methanocaldococcus jannaschii
RepID=HACA_METJA
Length = 420
Score = 115 bits (288), Expect = 2e-24
Identities = 72/201 (35%), Positives = 103/201 (51%), Gaps = 9/201 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV---------YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNR 154
D +TY YL+ + + E + + +A + E D+T +E VA PH PDN
Sbjct: 224 DEITYDYLKKERGLSDEDIAKLKKERITVNRDEANYYKEIEIDITDMEEQVAVPHHPDNV 283
Query: 155 ALARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVY 334
+ + +IN+V+IGSCT G+ D AAK +L V ++PA++KV++
Sbjct: 284 KPISDVEGTEINQVFIGSCTNGRLSDLREAAK-YLKGREVHKDVKLIVIPASKKVFLQAL 342
Query: 335 SLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGR 514
+ IF +AG +P CG CLG + A E ++C+STTNRNF GR
Sbjct: 343 K--------EGIIDIFVKAGA-MICTPGCGPCLGAHQGVLA---EGEICLSTTNRNFKGR 390
Query: 515 MGHREGEIYLASPYTAAASAL 577
MGH IYLASP AA SA+
Sbjct: 391 MGHINSYIYLASPKIAAISAV 411
[203][TOP]
>UniRef100_B5IBY4 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IBY4_9EURY
Length = 409
Score = 115 bits (287), Expect = 3e-24
Identities = 66/177 (37%), Positives = 102/177 (57%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
++++ +D++A ++ E DV LEPL+A P +P N E + ++I+ +IGSCT G+
Sbjct: 242 FKAIEADKEAEYVEEIHIDVNNLEPLMASPPNPCNVHPVSEYEGMEIDGAFIGSCTNGRY 301
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
ED +AAAK+ GKK+KVP + P T+++W+ + + +IF EAG
Sbjct: 302 EDLVAAAKIL---KGKKLKVPLTITPTTREIWLRLMK--------EGIWEIFAEAGA-VL 349
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+P CG C G +V +STTNRN+PG+ G G++YL SP AAASA+
Sbjct: 350 TNPGCGGCAEGMPGLIG----DEVYLSTTNRNYPGKQG--PGKLYLVSPVIAAASAV 400
[204][TOP]
>UniRef100_B8FMM4 3-isopropylmalate dehydratase large subunit n=1
Tax=Desulfatibacillum alkenivorans AK-01
RepID=LEUC_DESAA
Length = 419
Score = 115 bits (287), Expect = 3e-24
Identities = 71/192 (36%), Positives = 101/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D+ T +Y +G+ SD A++ +DVT LEP VA PH P+N + +V
Sbjct: 231 DAKTKEYADGRVIRKPVFYASDPDAKYAKVIEYDVTDLEPQVAFPHLPENTRPISQVGEV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
I++V IGSCT G+ ED +AA++ + K V ++PAT +++
Sbjct: 291 PIHQVIIGSCTNGRIEDMRSAARILTGNKADK-NVRLIIIPATPQIYRQAME-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ F AG + P+CG CLGG A + V+TTNRNF GRMGH E E+Y
Sbjct: 342 EGLFDTFLSAGA-VISPPTCGPCLGGHMGILA---AGERAVATTNRNFVGRMGHVESEVY 397
Query: 542 LASPYTAAASAL 577
LA+P AAASA+
Sbjct: 398 LANPAVAAASAI 409
[205][TOP]
>UniRef100_A7VNU8 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
RepID=A7VNU8_9CLOT
Length = 428
Score = 114 bits (286), Expect = 4e-24
Identities = 75/194 (38%), Positives = 100/194 (51%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT Y G+ +D+ A + EY D++ L P VA PH P+N V
Sbjct: 231 DDVTRAYCNGRFQGTPVEYAADEDAVYEKEYVIDLSALRPTVAFPHLPENTRTIDNVGQV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AA + GKKV V + P TQ +++D
Sbjct: 291 KIDQVVIGSCTNGRLSDLRIAANLL---KGKKVAKNVRCIVFPGTQTIYLDAMR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG A + VSTTNRNF GRMGH + E
Sbjct: 342 --EGLVEAFIQAGA-VVSTPTCGPCLGGHMGILA---AGERAVSTTNRNFVGRMGHVDSE 395
Query: 536 IYLASPYTAAASAL 577
+YLASP AAASA+
Sbjct: 396 VYLASPAVAAASAV 409
[206][TOP]
>UniRef100_C3MUB5 3-isopropylmalate dehydratase n=2 Tax=Sulfolobus islandicus
RepID=C3MUB5_SULIM
Length = 415
Score = 114 bits (286), Expect = 4e-24
Identities = 69/192 (35%), Positives = 100/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ E V D A+++ EY + ++EPLVA PHS DN + E +
Sbjct: 229 DQETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDEMEPLVAAPHSVDNVKVVNELEGT 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ +
Sbjct: 289 PVDQVYIGSCTNGRLSDFEIAAKIM---KGKKVKSRCIAIPASYRMFKEALE-------- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ Q +AGC +CG CLGG + + VST++RNF GRMG E +Y
Sbjct: 338 RGYIQTLVDAGCIITYG-TCGPCLGG---HFGIAGPGENIVSTSSRNFKGRMGSNEARVY 393
Query: 542 LASPYTAAASAL 577
L+ P AA SAL
Sbjct: 394 LSGPAVAAISAL 405
[207][TOP]
>UniRef100_B0KAH5 3-isopropylmalate dehydratase large subunit n=3
Tax=Thermoanaerobacter RepID=LEUC_THEP3
Length = 417
Score = 114 bits (286), Expect = 4e-24
Identities = 71/194 (36%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++G+ Y+ D A + Y + ++ P VA PH P+N E V
Sbjct: 229 DEITEAYVKGRAKREYKVFERDVDAEYSEVYEISLDEIRPQVAFPHLPENTRNIDEVGKV 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D A K+ GKKV V + PATQ+++++
Sbjct: 289 KIDQVVIGSCTNGRISDMEIAYKIL---KGKKVHPDVRLLIFPATQEIYLECVK------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F +AG ++P+CG CLGG A+ + ++TTNRNF GRMGH E E
Sbjct: 340 --RGYIEEFIKAGA-AVSTPTCGPCLGGHMGILAK---GERALATTNRNFVGRMGHPESE 393
Query: 536 IYLASPYTAAASAL 577
+YL+SP AAASA+
Sbjct: 394 VYLSSPAVAAASAI 407
[208][TOP]
>UniRef100_A6Q5L6 3-isopropylmalate dehydratase large subunit n=1 Tax=Nitratiruptor
sp. SB155-2 RepID=LEUC_NITSB
Length = 421
Score = 114 bits (286), Expect = 4e-24
Identities = 78/197 (39%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV-YSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARECK 175
D VT +L K + YSD+ A + DV LEP++A PH P N R ++ K
Sbjct: 230 DEVTKAFLADKPLAREPKIHYSDEDAEYEQVIEIDVNNLEPVIAFPHLPSNGRPISEAAK 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
D+K+++V+IGSCT G+ D AA++ G+KV T ++ PATQK+ +
Sbjct: 290 MDLKVDQVFIGSCTNGRLSDIAIAAEILK---GRKVARHTRMIVTPATQKILKEAEK--- 343
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ I +AG ++P+CGACLGG A + + CVSTTNRNF GRMG R
Sbjct: 344 -----RGYIDILIDAGA-VVSNPTCGACLGGYMGILA---DNERCVSTTNRNFVGRMGAR 394
Query: 527 EGEIYLASPYTAAASAL 577
EIYLA+ AAASA+
Sbjct: 395 TSEIYLANSAVAAASAV 411
[209][TOP]
>UniRef100_Q1Q122 Similar to 3-isopropylmalate dehydratase, large subunit n=1
Tax=Candidatus Kuenenia stuttgartiensis
RepID=Q1Q122_9BACT
Length = 437
Score = 114 bits (285), Expect = 5e-24
Identities = 69/194 (35%), Positives = 103/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y+ G+ Y + +SD + + Y F+ ++ P VA P P+N + +
Sbjct: 238 DKITENYVAGRVKREYVAYHSDPDSHYSKVYEFNAEEIVPQVALPSLPENTKSVYDVCGI 297
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI++V IGSCT G+ D AAK+ GKK + ++PATQ+++
Sbjct: 298 KIDQVVIGSCTNGRISDLRIAAKIL---KGKKAHPSLRLIIIPATQEIYKQALK------ 348
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ +IF +A ++P+CG CLGG A E + ++TTNRNF GRMGH + E
Sbjct: 349 --EGLIEIFIDAEA-VVSTPTCGPCLGGHMGILA---EGERALTTTNRNFVGRMGHPKSE 402
Query: 536 IYLASPYTAAASAL 577
IYL SP AAASA+
Sbjct: 403 IYLCSPAVAAASAI 416
[210][TOP]
>UniRef100_C3RJS7 Putative uncharacterized protein n=1 Tax=Mollicutes bacterium D7
RepID=C3RJS7_9MOLU
Length = 422
Score = 114 bits (285), Expect = 5e-24
Identities = 77/197 (39%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T Y+E + Y +D+ A + D+ K+ P VA PH P N E +
Sbjct: 228 DEQTIAYMEKHSVKEYAVYEADEDAEYDEVIEIDLGKVRPTVAFPHLPGNGHTIDEIEAM 287
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPV 346
+ I++V IGSCT G+ D AA + GK+V V +VPATQK+++
Sbjct: 288 DKIMIDQVVIGSCTNGRLSDLRKAAAILK---GKQVAKNVRVMVVPATQKIFVQCIH--- 341
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ ++IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG
Sbjct: 342 -----EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAKGEK---CVSTTNRNFVGRMGDT 392
Query: 527 EGEIYLASPYTAAASAL 577
E IYLASP AAASA+
Sbjct: 393 EALIYLASPEVAAASAI 409
[211][TOP]
>UniRef100_B0N943 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
1402 RepID=B0N943_9FIRM
Length = 424
Score = 114 bits (285), Expect = 5e-24
Identities = 77/197 (39%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T Y+E + Y +D+ A + D+ K+ P VA PH P N E +
Sbjct: 230 DEQTIAYMEKHSVKEYAVYEADEDAEYDEVIEIDLGKVRPTVAFPHLPGNGHTIDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPV 346
+ I++V IGSCT G+ D AA + GK+V V +VPATQK+++
Sbjct: 290 DKIMIDQVVIGSCTNGRLSDLRKAAAILK---GKQVAKNVRVMVVPATQKIFVQCIH--- 343
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ ++IF EAGC +PSCG C+GG A+ + CVSTTNRNF GRMG
Sbjct: 344 -----EGLAEIFVEAGCAFN-TPSCGPCMGGHMGVMAKGEK---CVSTTNRNFVGRMGDT 394
Query: 527 EGEIYLASPYTAAASAL 577
E IYLASP AAASA+
Sbjct: 395 EALIYLASPEVAAASAI 411
[212][TOP]
>UniRef100_C3MKR7 3-isopropylmalate dehydratase n=1 Tax=Sulfolobus islandicus
L.S.2.15 RepID=C3MKR7_SULIL
Length = 415
Score = 114 bits (285), Expect = 5e-24
Identities = 69/192 (35%), Positives = 100/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +Y++ E V D A+++ EY + ++EPLVA PHS DN + E
Sbjct: 229 DQETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDEMEPLVAAPHSVDNVKVVNELGGT 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ +
Sbjct: 289 PVDQVYIGSCTNGRLSDFEIAAKIM---KGKKVKSRCIAIPASYRMFKEALE-------- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ Q +AGC +CG CLGG + + VST++RNF GRMG E ++Y
Sbjct: 338 RGYIQTLVDAGCIVTYG-TCGPCLGG---HFGIAGPGENIVSTSSRNFKGRMGSNEAKVY 393
Query: 542 LASPYTAAASAL 577
L+ P AA SAL
Sbjct: 394 LSGPAVAAISAL 405
[213][TOP]
>UniRef100_A8EQZ0 3-isopropylmalate dehydratase large subunit n=1 Tax=Arcobacter
butzleri RM4018 RepID=LEUC_ARCB4
Length = 426
Score = 114 bits (285), Expect = 5e-24
Identities = 70/177 (39%), Positives = 102/177 (57%), Gaps = 4/177 (2%)
Frame = +2
Query: 59 YSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARECKD-VKINRVYIGSCTGGKTED 232
YSD+ A + DV KLEP++A P+ P N ++++ D +K+++V+IGSCT G+ D
Sbjct: 255 YSDEDANYCQVIEIDVAKLEPVIAYPYLPSNGHSVSQAVSDNIKVDQVFIGSCTNGRLSD 314
Query: 233 FMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
F AA++ G+KV V L P TQK+ + L + +AG
Sbjct: 315 FKIAAEIL---AGQKVARHVRLILTPGTQKILREATKLGYIDT--------LVDAGA-VV 362
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
++P+CGACLGG + + +VC+STTNRNF GRMG R +IYLA+ AAASA+
Sbjct: 363 SNPTCGACLGGYMGI---LGDNEVCISTTNRNFVGRMGSRSSKIYLANSAVAAASAI 416
[214][TOP]
>UniRef100_B6FST2 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FST2_9CLOT
Length = 438
Score = 114 bits (284), Expect = 7e-24
Identities = 75/197 (38%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD- 178
D Y++ + Y+ +D+ A + D++K+ P VA PH P N E ++
Sbjct: 244 DEKAEAYMKEHSEKEYKVYTADEDAEYDEVVEIDLSKVRPTVAFPHLPGNAKTIDEVEEM 303
Query: 179 --VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPV 346
+KI++V IGSCT G+ ED AA V G KV V ++PATQK+++
Sbjct: 304 EPIKIDQVVIGSCTNGRMEDMRRAAAVLK---GHKVHPDVRVMVIPATQKIYLQCIE--- 357
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ F E+GC +PSCG C+GG A + CVSTTNRNF GRMGH
Sbjct: 358 -----EGLVTTFIESGCAFN-TPSCGPCMGGHMGVMAAGEK---CVSTTNRNFVGRMGHV 408
Query: 527 EGEIYLASPYTAAASAL 577
+ IYLASP AAASA+
Sbjct: 409 DSLIYLASPEVAAASAI 425
[215][TOP]
>UniRef100_B0A9M7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
16795 RepID=B0A9M7_9CLOT
Length = 429
Score = 114 bits (284), Expect = 7e-24
Identities = 78/199 (39%), Positives = 105/199 (52%), Gaps = 7/199 (3%)
Frame = +2
Query: 2 DSVTYKYLEG---KTSVPYESVY-SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARE 169
D T +Y+E KT +VY +D+ A + D+++L+P VA PH P+N E
Sbjct: 231 DEKTKEYMEAHPCKTIEKNPTVYEADEDAEYDRVIEIDLSELKPTVAFPHLPENTKTTDE 290
Query: 170 C-KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSL 340
+D+KI++V IGSCT G+ ED AA++ GKKV V + P TQ ++++
Sbjct: 291 ITEDIKIDQVVIGSCTNGRIEDMRIAAEIMR---GKKVADDVRCIVFPGTQAIYLEAIEK 347
Query: 341 PVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMG 520
G + A TP +CG CLGG A VSTTNRNF GRMG
Sbjct: 348 ------GYITDMVLAGAAISTP---TCGPCLGGHMGILAAGER---AVSTTNRNFVGRMG 395
Query: 521 HREGEIYLASPYTAAASAL 577
H E E+YLASP AAASA+
Sbjct: 396 HTESEVYLASPAVAAASAI 414
[216][TOP]
>UniRef100_Q703X6 3-isopropylmalate dehydratase large subunit n=1 Tax=Thermoproteus
tenax RepID=Q703X6_THETE
Length = 415
Score = 114 bits (284), Expect = 7e-24
Identities = 70/192 (36%), Positives = 102/192 (53%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
DS TY YLE KT V +++ EY ++ +LEPLVA PHS DN RE + V
Sbjct: 229 DSETYAYLE-KTRGAAPRVDFVPGGKYIDEYTVELDRLEPLVAAPHSVDNVKSVREVEGV 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++V+IGSCT G+ D AAA++ + K +PA+ V+
Sbjct: 288 EVDQVFIGSCTNGRLSDIEAAARILKRG---RAKARCIAIPASYSVFRQALEAGY----- 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ +AGC +CG C+GG + + + VST+NRNF GRMG + ++Y
Sbjct: 340 ---IDVLTKAGC-VVTYGTCGPCIGG---HFGVLGPGETAVSTSNRNFVGRMGANDSKVY 392
Query: 542 LASPYTAAASAL 577
LA+ YTAAA+AL
Sbjct: 393 LANAYTAAAAAL 404
[217][TOP]
>UniRef100_C5U763 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
infernus ME RepID=C5U763_9EURY
Length = 424
Score = 114 bits (284), Expect = 7e-24
Identities = 66/177 (37%), Positives = 93/177 (52%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
++ + D+ A F Y + K+EP+ A PH+ DN RE I++V+IGSCT G+
Sbjct: 250 FKPIKGDEDAEFSEVYEIEADKIEPVFACPHNVDNVKQCREVAGKPIDQVFIGSCTNGRL 309
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
ED A V GG V + PA+++ ++ + + F + GC
Sbjct: 310 EDLRMAINVIEKHGGIAEDVRVIVTPASREEYLKALK--------EGIIEKFIKYGC-VV 360
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+PSC AC+G Y + +VCVST+NRNF GR G E EIYLASP TAAA A+
Sbjct: 361 TNPSCSACMG---SLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACAV 414
[218][TOP]
>UniRef100_B5I9M1 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5I9M1_9EURY
Length = 409
Score = 114 bits (284), Expect = 7e-24
Identities = 66/177 (37%), Positives = 101/177 (57%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
++ + +D++A ++ E DV LEPL+A P +P N E + ++I+ +IGSCT G+
Sbjct: 242 FKVIKADKEAEYVEEIHIDVNNLEPLMASPPNPCNVHPVSEYEGMEIDGAFIGSCTNGRY 301
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
ED +AAAK+ GKK+KVP + P T+++W+ + + +IF EAG
Sbjct: 302 EDLVAAAKIL---KGKKLKVPLTITPTTREIWLRLMK--------EGIWEIFAEAGA-VL 349
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+P CG C G +V +STTNRN+PG+ G G++YL SP AAASA+
Sbjct: 350 TNPGCGGCAEGMPGLIG----DEVYLSTTNRNYPGKQG--PGKLYLVSPVIAAASAV 400
[219][TOP]
>UniRef100_C8PKG7 3-isopropylmalate dehydratase large subunit n=1 Tax=Campylobacter
gracilis RM3268 RepID=C8PKG7_9PROT
Length = 421
Score = 113 bits (283), Expect = 9e-24
Identities = 78/197 (39%), Positives = 109/197 (55%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKT-SVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-- 172
D +T ++L K + YSD+ A + + DV+KL+P++A P P N RE
Sbjct: 230 DEITKEFLADKNLRAEPKFHYSDEGANYEQILQIDVSKLDPVIAYPFLPSNGKSVREAVR 289
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
D+ +++V+IGSCT G+ D AA++ G+KV T L+ PATQK+ +L
Sbjct: 290 DDIAVDQVFIGSCTNGRLSDLRIAAQILK---GRKVARKTRLIITPATQKI-----ALAA 341
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
G IF EAG ++P+CGACLGG + + CVSTTNRNF GRMG R
Sbjct: 342 QKEG---LWDIFVEAGA-VVSNPTCGACLGGYMGI---LGVGERCVSTTNRNFVGRMGDR 394
Query: 527 EGEIYLASPYTAAASAL 577
E+YLA+ AAASA+
Sbjct: 395 TSEVYLANSAVAAASAV 411
[220][TOP]
>UniRef100_B5CQV8 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
29176 RepID=B5CQV8_9FIRM
Length = 424
Score = 113 bits (283), Expect = 9e-24
Identities = 75/195 (38%), Positives = 99/195 (50%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D T YL Y +D+ A + D++K+ P VA PH P N E +
Sbjct: 230 DEKTKAYLAEHCKKEYTVYEADEDAVYDEVIEIDLSKVRPTVAFPHLPGNAKTIDEVEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPG 352
+KI++V IGSCT G+ ED AA + L V ++PATQK++ +
Sbjct: 290 EPIKIDQVVIGSCTNGRMEDLRKAAAI-LKGHTVHPDVRVMVIPATQKIYKECIK----- 343
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH +
Sbjct: 344 ---EGLLDIFVDAGCAVN-TPSCGPCMGGHMGVMAAGEK---CVSTTNRNFVGRMGHVDS 396
Query: 533 EIYLASPYTAAASAL 577
IYLASP AAASA+
Sbjct: 397 LIYLASPEVAAASAI 411
[221][TOP]
>UniRef100_B0NJ74 Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC
35704 RepID=B0NJ74_EUBSP
Length = 424
Score = 113 bits (283), Expect = 9e-24
Identities = 76/197 (38%), Positives = 103/197 (52%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D +Y++ + Y+ +D A + + D+ K+ P VA PH P N E +
Sbjct: 230 DEKAEEYMKEHSDKEYKIYEADADADYDAVVEVDLAKVRPTVAFPHLPGNAKTIDEIEAM 289
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPV 346
+KI++V IGSCT G+ ED AA V G+KV V ++PATQK++
Sbjct: 290 EPIKIDQVVIGSCTNGRMEDMRRAAAVLK---GRKVHPDVRVMVIPATQKIYKQCIK--- 343
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH
Sbjct: 344 -----EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAAGEK---CVSTTNRNFVGRMGHV 394
Query: 527 EGEIYLASPYTAAASAL 577
+ IYLASP AAASA+
Sbjct: 395 DSLIYLASPEVAAASAI 411
[222][TOP]
>UniRef100_A6NUW5 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
ATCC 29799 RepID=A6NUW5_9BACE
Length = 422
Score = 113 bits (283), Expect = 9e-24
Identities = 72/194 (37%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT YL G+ + +E+ +D A + E D+ +L P VA PH P N + + +
Sbjct: 231 DDVTRAYLNGRVTREWEAFEADPDAVYEREVVIDLDQLRPTVALPHLPSNTRTVDQVEGM 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
I +V IGSCT G+ +D AA++ G+KV V + PATQ++ +D +
Sbjct: 291 PIQQVVIGSCTNGRLKDIKEAAEIL---KGRKVAKGVRCIVFPATQQIMLDAMAAGY--- 344
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
Q EAGC ++P+CG CLGG +++ + +STTNRNF GRMG E
Sbjct: 345 -----IQTLVEAGC-AVSTPTCGPCLGGHMGV---LSDGERAISTTNRNFVGRMGPVSSE 395
Query: 536 IYLASPYTAAASAL 577
I L+SP AAASA+
Sbjct: 396 IILSSPAVAAASAV 409
[223][TOP]
>UniRef100_A1HRB9 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HRB9_9FIRM
Length = 420
Score = 113 bits (283), Expect = 9e-24
Identities = 75/195 (38%), Positives = 102/195 (52%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGK-TSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD 178
D+ +YL+ + + Y SD A F + YRFD ++LEP+VA PH DN K
Sbjct: 230 DTKVVEYLKARGITEGYTLFASDSDAVFCATYRFDASELEPVVACPHEVDNVTELSNVKG 289
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
I++ YIGSCTGG+ D AAA+V G+KV V + PA+ ++W
Sbjct: 290 QVIHQAYIGSCTGGRYNDLAAAARVL---KGRKVANGVRLLVSPASHEIWRQ-------- 338
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ I EAG A P+CG C+G A + + C+S+TNRNF GRMG +
Sbjct: 339 AAADGILSILAEAGAIILA-PTCGVCVGLHSGLLA---DGEYCISSTNRNFIGRMGSKNA 394
Query: 533 EIYLASPYTAAASAL 577
IYLASP AASA+
Sbjct: 395 GIYLASPMAVAASAI 409
[224][TOP]
>UniRef100_C8SBC1 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SBC1_FERPL
Length = 427
Score = 113 bits (283), Expect = 9e-24
Identities = 73/195 (37%), Positives = 105/195 (53%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYL-EGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKD 178
D VT K+L E + + D+ A + E FDV+ L P+VAKPH DN A E +
Sbjct: 237 DEVTKKFLMERGRGDKFREIKPDEDAEYEKEMYFDVSDLTPIVAKPHQVDNIARIDEVEG 296
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPG 352
VK+++V++G+CT G+ D A++ G+KV V + PA+++V+M
Sbjct: 297 VKVDQVFVGTCTNGRLSDLEVVARIL---KGRKVHKDVRLLVGPASREVYMKALERGY-- 351
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+I + G P P CG C+G A + +VC+ST NRNF GRMG+
Sbjct: 352 -----IQEIIKAGGVILP--PGCGPCVGIHLGILA---DGEVCLSTQNRNFKGRMGNPNA 401
Query: 533 EIYLASPYTAAASAL 577
EIYL+SP TAAASA+
Sbjct: 402 EIYLSSPATAAASAI 416
[225][TOP]
>UniRef100_Q7M9Z9 3-isopropylmalate dehydratase large subunit n=1 Tax=Wolinella
succinogenes RepID=LEUC_WOLSU
Length = 422
Score = 113 bits (283), Expect = 9e-24
Identities = 75/198 (37%), Positives = 111/198 (56%), Gaps = 6/198 (3%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVY--SDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALAREC 172
DS+T ++L + S+ E Y +D A + DV KLEP++A P P N +++++
Sbjct: 230 DSITKEFLASRKSLRAEPKYYQADADALYEQTIEIDVEKLEPVIAYPFLPSNGKSISQAV 289
Query: 173 KD-VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLP 343
KD +KI++ +IGSCT G+ D AA++ GK+V V + P TQ+++ D +
Sbjct: 290 KDDLKIDQAFIGSCTNGRLSDLRIAAQILK---GKRVHPDVRLIITPGTQQIYKDAHQ-- 344
Query: 344 VPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGH 523
+ EAG ++P+CGACLGG + + + CVSTTNRNF GRMG
Sbjct: 345 ------EGLIDTLLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGA 394
Query: 524 REGEIYLASPYTAAASAL 577
R E+YLA+ AAASAL
Sbjct: 395 RSSEVYLANSAVAAASAL 412
[226][TOP]
>UniRef100_A7IA28 3-isopropylmalate dehydratase large subunit n=1 Tax=Candidatus
Methanoregula boonei 6A8 RepID=LEUC_METB6
Length = 416
Score = 113 bits (283), Expect = 9e-24
Identities = 69/194 (35%), Positives = 109/194 (56%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D VT++Y++G+ + ++ SD A+F + ++V LEP VA PH+ D + +
Sbjct: 228 DKVTWEYMKGRRKITPFALASDDDAKFAEKRTYNVADLEPQVAVPHNVDQGIPVGKVEGT 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I++V+IGSCT G+ ED + AA+V G KK KV ++PA++ ++ +
Sbjct: 288 HIDQVFIGSCTNGRYEDLVEAAEVL---GKKKFDPKVRVLVIPASRDEYLKALEAGL--- 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ F AG A P CG C+GG ++ + +V ++T+NRNF GR G EG+
Sbjct: 342 -----VERFVRAGALVEA-PCCGPCMGG---SFGLIAAGEVSLATSNRNFRGRQGSTEGK 392
Query: 536 IYLASPYTAAASAL 577
+YL SP TAAASA+
Sbjct: 393 VYLCSPATAAASAI 406
[227][TOP]
>UniRef100_C5F2A2 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
pullorum MIT 98-5489 RepID=C5F2A2_9HELI
Length = 422
Score = 113 bits (282), Expect = 1e-23
Identities = 74/199 (37%), Positives = 113/199 (56%), Gaps = 7/199 (3%)
Frame = +2
Query: 2 DSVTYKYLEGKTSV---PYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALARE 169
D +T ++L+ + + P E YSD A + + D++KLEP++A P P N +++++
Sbjct: 230 DEITREFLKSRPFLRANPRE-FYSDADANYTQTIQIDISKLEPVIAYPFLPSNGKSISQA 288
Query: 170 CKD-VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSL 340
KD +KI++V+IGSCT G+ D A+++ GKKV V + P TQ ++ + + L
Sbjct: 289 LKDDLKIDQVFIGSCTNGRLSDLKIASEILK---GKKVHQDVRLIITPGTQNIYKEAHKL 345
Query: 341 PVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMG 520
I EAG ++P+CGACLGG + + + CVSTTNRNF GRMG
Sbjct: 346 GY--------IDILLEAGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMG 393
Query: 521 HREGEIYLASPYTAAASAL 577
R E+YLA+ AA SA+
Sbjct: 394 ARNSEVYLANSAVAAISAI 412
[228][TOP]
>UniRef100_C0BZF9 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0BZF9_9CLOT
Length = 431
Score = 113 bits (282), Expect = 1e-23
Identities = 77/197 (39%), Positives = 102/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK-- 175
D Y++ + Y +D+ A + D++K+ P VA PH P N E +
Sbjct: 237 DEQAETYMKEHSDKSYTIYEADEDAVYDEVVEIDLSKVRPTVAFPHLPGNAKTIDEIEAM 296
Query: 176 -DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPV 346
V+I++V IGSCT G+ ED AA V G KV V ++PATQK++ S
Sbjct: 297 EPVRIDQVVIGSCTNGRMEDMRRAAAVLK---GHKVHPDVRAMIIPATQKIYKQCIS--- 350
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
+ IF +AGC +PSCG C+GG A + CVSTTNRNF GRMGH
Sbjct: 351 -----EGLVDIFIDAGCAFN-TPSCGPCMGGHMGVLAAGEK---CVSTTNRNFVGRMGHV 401
Query: 527 EGEIYLASPYTAAASAL 577
+ IYLASP AAASA+
Sbjct: 402 DSLIYLASPEVAAASAI 418
[229][TOP]
>UniRef100_C5CJ10 Homoaconitate hydratase family protein n=1 Tax=Kosmotoga olearia
TBF 19.5.1 RepID=C5CJ10_KOSOT
Length = 417
Score = 112 bits (281), Expect = 2e-23
Identities = 67/177 (37%), Positives = 100/177 (56%)
Frame = +2
Query: 47 YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDVKINRVYIGSCTGGKT 226
Y + SD A + Y DV+ LEP VA PH+ DN E + +KI++V+IG+CT G+
Sbjct: 242 YREIKSDPDAVYEKIYEIDVSNLEPAVALPHTVDNTKSISEVEGIKIDQVFIGTCTNGRL 301
Query: 227 EDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTP 406
ED AA + L K V ++PA+++V++ + +IF E+G T
Sbjct: 302 EDLRVAASI-LKGREKHPDVRLIVIPASKEVYLKALE--------EGLIKIFVESGA-TV 351
Query: 407 ASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
+P CG C+G + + + + +ST NRNF GRMG+ + EI+LASP TAAASA+
Sbjct: 352 LAPGCGPCVGVHQGV---LGDGERVLSTQNRNFKGRMGNPKAEIFLASPATAAASAI 405
[230][TOP]
>UniRef100_A4J6Z5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum reducens MI-1 RepID=A4J6Z5_DESRM
Length = 418
Score = 112 bits (281), Expect = 2e-23
Identities = 71/194 (36%), Positives = 101/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T+ +L+ T + +V +D A + DV+ LEP VAKPH DN + E K +
Sbjct: 228 DDKTFAWLKQYTERQFTAVSADANANYYKVLELDVSNLEPQVAKPHRVDNVSPLSEVKGL 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
I + ++G+CT G+ ED AA + GKKV V + PA++K++++ V
Sbjct: 288 PIQQAFLGTCTNGRLEDLRIAASIL---AGKKVHPDVRFIVAPASRKIYLEAMEEGV--- 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
Q EAG +P CG C+G ++ + +ST NRNF GRMG+ E
Sbjct: 342 -----IQRLVEAGA-AVVTPGCGPCVGTHNGV---PSDGETVISTANRNFKGRMGNSNAE 392
Query: 536 IYLASPYTAAASAL 577
IYLASP T AASAL
Sbjct: 393 IYLASPATVAASAL 406
[231][TOP]
>UniRef100_C2A003 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurospirillum deleyianum DSM 6946
RepID=C2A003_SULDE
Length = 421
Score = 112 bits (281), Expect = 2e-23
Identities = 79/197 (40%), Positives = 105/197 (53%), Gaps = 5/197 (2%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV-YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-- 172
D +T +L K YSD A ++ DV L+P++A P P N E
Sbjct: 230 DEITKAFLSDKNLAREPKFFYSDDDATYVQVLHIDVANLDPVIAYPFLPSNGKSINEAVK 289
Query: 173 KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLV--PATQKVWMDVYSLPV 346
D+ I++V+IGSCT G+ ED AA + G+KV T L+ PATQK+ SL
Sbjct: 290 DDLAIDQVFIGSCTNGRLEDLRIAASILK---GRKVARKTRLIITPATQKI-----SLQA 341
Query: 347 PGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHR 526
G +IF EAG ++P+CGACLGG + + + CV+TTNRNF GRMG R
Sbjct: 342 QKEG---LVEIFIEAGA-VFSNPTCGACLGGYMGI---LGKNERCVATTNRNFVGRMGDR 394
Query: 527 EGEIYLASPYTAAASAL 577
EIYLA+ AAASA+
Sbjct: 395 TSEIYLANSAVAAASAV 411
[232][TOP]
>UniRef100_C0B4W1 Putative uncharacterized protein n=1 Tax=Coprococcus comes ATCC
27758 RepID=C0B4W1_9FIRM
Length = 417
Score = 112 bits (281), Expect = 2e-23
Identities = 69/194 (35%), Positives = 102/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D V +YL+ P +SD A ++ EY FD++K+EP+VAKP DN A A++ + +
Sbjct: 229 DDVAMEYLKEHGREPKAVYHSDPDAHYVREYTFDLSKVEPVVAKPDFVDNLAPAKDVRGI 288
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
KI+ ++GSC G+ ED A+V GKKV KV +VPA+Q ++
Sbjct: 289 KIDEAFLGSCNNGRIEDLRVGAQVI---KGKKVSEKVRFLVVPASQTIYRQALE------ 339
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +AG +P+C C G + + E +V +ST RNF GR GH +
Sbjct: 340 --EGLIDIFMDAGA-IVMNPNCSVCWGSCQGV---IGENEVLISTGTRNFKGRAGHPSSK 393
Query: 536 IYLASPYTAAASAL 577
+YL S T ASA+
Sbjct: 394 VYLGSAATVTASAI 407
[233][TOP]
>UniRef100_Q18AJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile 630 RepID=LEUC_CLOD6
Length = 425
Score = 112 bits (281), Expect = 2e-23
Identities = 77/199 (38%), Positives = 105/199 (52%), Gaps = 7/199 (3%)
Frame = +2
Query: 2 DSVTYKYLEG---KTSVPYESVY-SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARE 169
D T +Y+ T ++Y +D+ A + Y D+ KL+ VA PH P+N E
Sbjct: 231 DDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETVAFPHLPENTRTVDE 290
Query: 170 C-KDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSL 340
KD+KI++V IGSCT G+ D A++ GKKV V + P TQKV+++
Sbjct: 291 IDKDIKIDQVVIGSCTNGRISDLEVVAEIMK---GKKVADGVRVMIFPGTQKVYLEAIE- 346
Query: 341 PVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMG 520
K F EAG ++P+CG CLGG A + +STTNRNF GRMG
Sbjct: 347 -------KGYITTFIEAGAAV-STPTCGPCLGGHMGILAAGEKS---ISTTNRNFVGRMG 395
Query: 521 HREGEIYLASPYTAAASAL 577
H + E+YLASP AAASA+
Sbjct: 396 HVDSEVYLASPAVAAASAI 414
[234][TOP]
>UniRef100_UPI000038E0FA 3-isopropylmalate dehydratase large subunit n=1 Tax=Ferroplasma
acidarmanus fer1 RepID=UPI000038E0FA
Length = 413
Score = 112 bits (280), Expect = 2e-23
Identities = 71/194 (36%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T +YL + + Y+ V SD+ A F + D+ +EP +A P+SPDN +A +
Sbjct: 226 DEKTIEYLNQRNTGSYKIVKSDENADFSQTFNIDMNNIEPSIAIPNSPDNVRIASAIHE- 284
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
KI++ YIGSCT G+ ED AA + G+KV V +VPA+Q+V+ +
Sbjct: 285 KIDQAYIGSCTNGRIEDIRKAAAILK---GRKVNRNVRLMVVPASQEVYNQALREGL--- 338
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ I E G + +CGACLGG + +VC+S+TNRNF GRMG + +
Sbjct: 339 ----INTIVEAGGYFS--GTTCGACLGGYMGV---LGPDEVCISSTNRNFIGRMGDKTSK 389
Query: 536 IYLASPYTAAASAL 577
+YLA+P A+SA+
Sbjct: 390 VYLANPSIVASSAI 403
[235][TOP]
>UniRef100_Q1IZK5 3-isopropylmalate dehydratase large subunit n=1 Tax=Deinococcus
geothermalis DSM 11300 RepID=Q1IZK5_DEIGD
Length = 431
Score = 112 bits (280), Expect = 2e-23
Identities = 76/202 (37%), Positives = 102/202 (50%), Gaps = 10/202 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVP--YESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECK 175
D T Y+ + P Y SD AR+ D +K+EP VA PH P N +A + +
Sbjct: 231 DDTTRAYMAARGVTPDQYTEYTSDPDARYKVVIDLDASKVEPTVAYPHIPSNGRVAGQDR 290
Query: 176 DVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVP 349
+ I Y+GSCT G+ D A++ G++V V +VPATQ +W
Sbjct: 291 -IPITHAYVGSCTNGRIGDLRDVARILK---GRRVADGVQMIVVPATQAIWKQ------- 339
Query: 350 GSGGKTCSQIFEEAGCDTPASPSCGACLG------GPKDTYARMNEPQVCVSTTNRNFPG 511
+ + +IF EAG + PSCGACLG GP D VC+S++NRNF G
Sbjct: 340 -AAQEGLLEIFVEAGASV-SYPSCGACLGMHSGVLGPGD---------VCISSSNRNFVG 388
Query: 512 RMGHREGEIYLASPYTAAASAL 577
RMG +IYLASP T AASA+
Sbjct: 389 RMGDPSAQIYLASPATVAASAV 410
[236][TOP]
>UniRef100_A6TSE5 3-isopropylmalate dehydratase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TSE5_ALKMQ
Length = 425
Score = 112 bits (280), Expect = 2e-23
Identities = 71/195 (36%), Positives = 106/195 (54%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D Y++ +T +E + +D + + Y F+V L+P VA PHS DN + K+V
Sbjct: 227 DEKIIAYVKERTGKTFEILKTDDDYEYAASYTFNVEDLKPQVALPHSVDNGVDIDKIKEV 286
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPT--FLVPATQKVWMDVYSLPVPGS 355
K+++V+IG+CTGG+ ED AA++ K+ T ++PA+++V
Sbjct: 287 KVDQVFIGTCTGGRLEDIEVAARII---KNNKIHRDTRLLVIPASKEVLEKAIE------ 337
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEP-QVCVSTTNRNFPGRMGHREG 532
K +AG T SP CG CLG T+ + P +VC +T++RNFPGRMG E
Sbjct: 338 --KGYMTTLIKAGA-TFTSPGCGPCLG----THQGLLAPGEVCATTSSRNFPGRMGSTEA 390
Query: 533 EIYLASPYTAAASAL 577
+IYL SP TAAA A+
Sbjct: 391 DIYLVSPATAAAIAI 405
[237][TOP]
>UniRef100_Q2LWJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Syntrophus
aciditrophicus SB RepID=LEUC_SYNAS
Length = 420
Score = 112 bits (280), Expect = 2e-23
Identities = 71/194 (36%), Positives = 101/194 (52%), Gaps = 2/194 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y++ + PY SD A + DV ++EP VA PH P N E V
Sbjct: 231 DEITEAYVKPRAKRPYTFYASDPDAAYAQVIEIDVNRIEPQVAFPHLPSNTKGISEVGQV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVYSLPVPGS 355
+++V IGSCT G+ ED AAA V G+K +V ++PATQ+++
Sbjct: 291 PLDQVVIGSCTNGRIEDLRAAAAVL---KGRKADPRVRLIVIPATQEIYRMAMK------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ IF +A ++P+CG CLGG A + ++TTNRNF GRMGH E
Sbjct: 342 --EGLFDIFLDANA-AISTPTCGPCLGGHMGILA---AGERALATTNRNFVGRMGHPRSE 395
Query: 536 IYLASPYTAAASAL 577
+YL++P AAASA+
Sbjct: 396 VYLSNPAVAAASAV 409
[238][TOP]
>UniRef100_Q7VH31 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
hepaticus RepID=LEUC_HELHP
Length = 420
Score = 112 bits (280), Expect = 2e-23
Identities = 66/192 (34%), Positives = 101/192 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T Y +G+T + +D A + + D+ + VA PH P+N + ++
Sbjct: 231 DDITISYAKGRTKRDFRIYKADVDAEYEQVFDIDLDSINHTVAFPHLPENTKEKDDWGEI 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
KI++V IGSCT G+ D AA++ K ++PATQ ++++ +
Sbjct: 291 KIDQVVIGSCTNGRLSDMAVAAEILKDKTIAK-NTRCIIIPATQNIYLECIN-------- 341
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ + F +AG ++P+CG CLGG A + CVSTTNRNF GRMGH E+Y
Sbjct: 342 RGYLETFIKAGA-VVSTPTCGPCLGGHMGILAANEK---CVSTTNRNFVGRMGHITSEVY 397
Query: 542 LASPYTAAASAL 577
L+SP AAASA+
Sbjct: 398 LSSPEVAAASAV 409
[239][TOP]
>UniRef100_A4YF03 3-isopropylmalate dehydratase large subunit n=1 Tax=Metallosphaera
sedula DSM 5348 RepID=LEUC_METS5
Length = 415
Score = 112 bits (279), Expect = 3e-23
Identities = 70/191 (36%), Positives = 100/191 (52%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D T Y++ E V D A++L E+ ++ KLEPLVA P+S DN ARE V
Sbjct: 228 DVETKDYIKTMRGKEVELVTPDPGAKYLDEHTIELDKLEPLVAAPYSVDNVKTAREESKV 287
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
+++VYIGSCT G+ DF A+++ GKKVK +P++ ++ +
Sbjct: 288 PVDQVYIGSCTNGRLSDFRIASEIL---KGKKVKTRCIAIPSSYTMFKQAMEMGY----- 339
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ AGC +CG CLGG + +V VST++RNF GRMG E ++Y
Sbjct: 340 ---IEDLVNAGC-VVTYGTCGPCLGG---HFGVAGPGEVIVSTSSRNFRGRMGSNEAKVY 392
Query: 542 LASPYTAAASA 574
L+ P AAASA
Sbjct: 393 LSGPSVAAASA 403
[240][TOP]
>UniRef100_C5ZZ28 3-isopropylmalate dehydratase, large subunit n=1 Tax=Helicobacter
canadensis MIT 98-5491 RepID=C5ZZ28_9HELI
Length = 421
Score = 111 bits (278), Expect = 4e-23
Identities = 71/198 (35%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYE--SVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDN-RALAREC 172
D +T ++L + + + YSD+ A + + D++ LEP++A P P N +++++
Sbjct: 230 DEITREFLASRKELRAKPKEFYSDKDANYTRVLKIDISTLEPVIAYPFLPSNGKSISQAL 289
Query: 173 KD-VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLP 343
KD +KI++V+IGSCT G+ D A+++ GKKV V + P TQ+++ + Y L
Sbjct: 290 KDDLKIDQVFIGSCTNGRLADLKIASEILK---GKKVHKDVRLIVTPGTQQIYKEAYQLG 346
Query: 344 VPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGH 523
I E+G ++P+CGACLGG + + + CVSTTNRNF GRMG
Sbjct: 347 Y--------IDILLESGA-LISNPTCGACLGGYMGI---LGDNERCVSTTNRNFVGRMGA 394
Query: 524 REGEIYLASPYTAAASAL 577
R E+YLA+ AA SA+
Sbjct: 395 RSSEVYLANSAVAAMSAI 412
[241][TOP]
>UniRef100_B0MLF2 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
15702 RepID=B0MLF2_9FIRM
Length = 418
Score = 111 bits (278), Expect = 4e-23
Identities = 68/195 (34%), Positives = 105/195 (53%), Gaps = 3/195 (1%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KD 178
D +T Y++ + ++ +D+ A + D++ ++ V+ PH P+N E +D
Sbjct: 231 DEITMAYMKERADRDFDIFKADEDAVYSRVIDIDLSTVKQTVSFPHLPENTKTVDEITED 290
Query: 179 VKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPG 352
+KI++ IGSCT G+ D AA++ GK + V ++P TQKV++
Sbjct: 291 IKIDQAVIGSCTNGRISDMRIAAEILK---GKHIAKGVRCIVIPGTQKVYLQCIK----- 342
Query: 353 SGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREG 532
+ ++IF AGC ++P+CG CLGG A +STTNRNF GRMGH +
Sbjct: 343 ---EGLAEIFVNAGC-VLSTPTCGPCLGGHMGILAAGER---AISTTNRNFVGRMGHVDS 395
Query: 533 EIYLASPYTAAASAL 577
E+YLASP AAASA+
Sbjct: 396 EVYLASPAVAAASAI 410
[242][TOP]
>UniRef100_C5U5J5 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
infernus ME RepID=C5U5J5_9EURY
Length = 416
Score = 111 bits (278), Expect = 4e-23
Identities = 71/201 (35%), Positives = 105/201 (52%), Gaps = 9/201 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV-------YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRAL 160
D +T+ YL + + E + ++ ++ E D+T++E +A PHSPDN
Sbjct: 223 DEITFNYLREERGLSEEKINKLKREAIKVEEGNYIKEIFIDITEMEEQIALPHSPDNVKP 282
Query: 161 ARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKV--KVPTFLVPATQKVWMDVY 334
E + ++I++V+IGSCT G+ ED AK GKKV V ++PA++KV++
Sbjct: 283 ISEVEGLEIDQVFIGSCTNGRIEDLRIVAKYL---KGKKVHKDVKLIIIPASKKVYLKAL 339
Query: 335 SLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGR 514
+ +IF +AG P CG CLG + A E +VC+ST+NRNF GR
Sbjct: 340 K--------EGLIEIFIKAGA-MICPPGCGPCLGAHQGVLA---EGEVCLSTSNRNFRGR 387
Query: 515 MGHREGEIYLASPYTAAASAL 577
MG IYL SP AA SA+
Sbjct: 388 MGDPNSYIYLCSPKIAAISAV 408
[243][TOP]
>UniRef100_A1VAE7 3-isopropylmalate dehydratase large subunit n=1 Tax=Desulfovibrio
vulgaris DP4 RepID=LEUC_DESVV
Length = 419
Score = 111 bits (278), Expect = 4e-23
Identities = 76/194 (39%), Positives = 102/194 (52%), Gaps = 3/194 (1%)
Frame = +2
Query: 5 SVTYKYLEGKTSVPYESVYS-DQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
++TY G+T ++ +S D A + E FDVT + P+VA PH PDN E KDV
Sbjct: 234 TLTYCTAAGRTG---DAAFSADAGAVYERELSFDVTGMTPVVACPHLPDNVKPVSEVKDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+ +V IGSCT G+ D AA V G+KV V ++PAT +W
Sbjct: 291 TVQQVVIGSCTNGRIGDLREAAAVL---RGRKVSRDVRCIVLPATPGIWRQALR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAGC +CG CLGG A + + ++TTNRNF GRMG E E
Sbjct: 342 --EGLIETFMEAGC-IVGPATCGPCLGGHMGILA---DGERAIATTNRNFKGRMGSLESE 395
Query: 536 IYLASPYTAAASAL 577
+YL+ P TAAASA+
Sbjct: 396 VYLSGPATAAASAV 409
[244][TOP]
>UniRef100_Q726X4 3-isopropylmalate dehydratase large subunit n=2 Tax=Desulfovibrio
vulgaris RepID=LEUC_DESVH
Length = 419
Score = 111 bits (278), Expect = 4e-23
Identities = 76/194 (39%), Positives = 102/194 (52%), Gaps = 3/194 (1%)
Frame = +2
Query: 5 SVTYKYLEGKTSVPYESVYS-DQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
++TY G+T ++ +S D A + E FDVT + P+VA PH PDN E KDV
Sbjct: 234 TLTYCTTAGRTG---DTAFSADAGAVYERELSFDVTGMTPVVACPHLPDNVKPVSEVKDV 290
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGS 355
+ +V IGSCT G+ D AA V G+KV V ++PAT +W
Sbjct: 291 TVQQVVIGSCTNGRIGDLREAAAVL---RGRKVSRDVRCIVLPATPGIWRQALR------ 341
Query: 356 GGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGE 535
+ + F EAGC +CG CLGG A + + ++TTNRNF GRMG E E
Sbjct: 342 --EGLIETFMEAGC-IVGPATCGPCLGGHMGILA---DGERAIATTNRNFKGRMGSLESE 395
Query: 536 IYLASPYTAAASAL 577
+YL+ P TAAASA+
Sbjct: 396 VYLSGPATAAASAV 409
[245][TOP]
>UniRef100_Q8ZW41 3-isopropylmalate dehydratase large subunit n=1 Tax=Pyrobaculum
aerophilum RepID=LEUC_PYRAE
Length = 415
Score = 111 bits (277), Expect = 5e-23
Identities = 68/191 (35%), Positives = 104/191 (54%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESVYSDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALARECKDV 181
D +T +YL+ + V Y + + +Y ++ +LEPLVA P+S DN RE + V
Sbjct: 227 DVITAEYLKTERGVDYTPPRIEP-GNYADKYTVELPRLEPLVAAPYSVDNIKSVREVEGV 285
Query: 182 KINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVYSLPVPGSGG 361
++++V+IGSCT G+ D AAK+ G++VK +PA+ +V+ L
Sbjct: 286 EVDQVFIGSCTNGRLSDIAVAAKIL---KGRRVKSRCIAIPASYEVFRRAMKLGY----- 337
Query: 362 KTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIY 541
+ EAGC +CG CLGG + +V V+T+NRNF GR+GH + +IY
Sbjct: 338 ---IDVLTEAGC-VVTYGTCGPCLGG---HFGVAGPGEVVVTTSNRNFRGRVGHPDAKIY 390
Query: 542 LASPYTAAASA 574
LA+P AAA+A
Sbjct: 391 LANPAVAAATA 401
[246][TOP]
>UniRef100_UPI0001B0C0E1 homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
vulcanius M7 RepID=UPI0001B0C0E1
Length = 449
Score = 110 bits (276), Expect = 6e-23
Identities = 70/201 (34%), Positives = 103/201 (51%), Gaps = 9/201 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV---------YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNR 154
D +TY YL+ + + + + + +A + E D+T +E +A PH PDN
Sbjct: 254 DEITYNYLKKERGLSDDDINKLKKERITVNKDEANYHKEVVIDITDMEEQIAVPHHPDNV 313
Query: 155 ALARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVY 334
E I++V+IGSCT G+ ED AAK +L V ++PA++KV++
Sbjct: 314 KPVSEVAGKAIDQVFIGSCTNGRLEDLREAAK-YLKGRRVHEDVKLIVIPASKKVFLQAL 372
Query: 335 SLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGR 514
+ ++F +AG +P CG CLG + A E +VC+STTNRNF GR
Sbjct: 373 K--------EGIIEVFIKAGA-MICTPGCGPCLGAHQGVLA---EGEVCLSTTNRNFRGR 420
Query: 515 MGHREGEIYLASPYTAAASAL 577
MGH IYL+SP AA SA+
Sbjct: 421 MGHINSYIYLSSPKIAAISAV 441
[247][TOP]
>UniRef100_UPI00016C5FE1 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile QCD-97b34 RepID=UPI00016C5FE1
Length = 425
Score = 110 bits (276), Expect = 6e-23
Identities = 71/175 (40%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
Frame = +2
Query: 62 SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KDVKINRVYIGSCTGGKTEDFM 238
+D+ A + Y D+ +L+ VA PH P+N E KD+KI++V IGSCT G+ D
Sbjct: 255 ADEDAVYDEVYEIDLAELKETVAFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLE 314
Query: 239 AAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTPAS 412
A++ GKKV V + P TQKV+++ K F EAG ++
Sbjct: 315 VVAEIMK---GKKVADGVRVMIFPGTQKVYLEAIE--------KGYITTFIEAGAAV-ST 362
Query: 413 PSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
P+CG CLGG A + +STTNRNF GRMGH + E+YLASP AAASA+
Sbjct: 363 PTCGPCLGGHMGILAAGEKS---ISTTNRNFVGRMGHVDSEVYLASPAVAAASAI 414
[248][TOP]
>UniRef100_UPI00006DC4EC hypothetical protein CdifQ_04001012 n=1 Tax=Clostridium difficile
QCD-32g58 RepID=UPI00006DC4EC
Length = 191
Score = 110 bits (276), Expect = 6e-23
Identities = 71/175 (40%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
Frame = +2
Query: 62 SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KDVKINRVYIGSCTGGKTEDFM 238
+D+ A + Y D+ +L+ VA PH P+N E KD+KI++V IGSCT G+ D
Sbjct: 21 ADEDAVYDEVYEIDLAELKETVAFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLE 80
Query: 239 AAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTPAS 412
A++ GKKV V + P TQKV+++ K F EAG ++
Sbjct: 81 VVAEIMK---GKKVADGVRVMIFPGTQKVYLEAIE--------KGYITTFIEAGAAV-ST 128
Query: 413 PSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
P+CG CLGG A + +STTNRNF GRMGH + E+YLASP AAASA+
Sbjct: 129 PTCGPCLGGHMGILAAGEKS---ISTTNRNFVGRMGHVDSEVYLASPAVAAASAI 180
[249][TOP]
>UniRef100_C9XME3 3-isopropylmalate dehydratase large subunit n=2 Tax=Clostridium
difficile RepID=C9XME3_CLODI
Length = 364
Score = 110 bits (276), Expect = 6e-23
Identities = 71/175 (40%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
Frame = +2
Query: 62 SDQQARFLSEYRFDVTKLEPLVAKPHSPDNRALAREC-KDVKINRVYIGSCTGGKTEDFM 238
+D+ A + Y D+ +L+ VA PH P+N E KD+KI++V IGSCT G+ D
Sbjct: 194 ADEDAVYDEVYEIDLAELKETVAFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLE 253
Query: 239 AAAKVFLASGGKKVK--VPTFLVPATQKVWMDVYSLPVPGSGGKTCSQIFEEAGCDTPAS 412
A++ GKKV V + P TQKV+++ K F EAG ++
Sbjct: 254 VVAEIMK---GKKVADGVRVMIFPGTQKVYLEAIE--------KGYITTFIEAGAAV-ST 301
Query: 413 PSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGRMGHREGEIYLASPYTAAASAL 577
P+CG CLGG A + +STTNRNF GRMGH + E+YLASP AAASA+
Sbjct: 302 PTCGPCLGGHMGILAAGEKS---ISTTNRNFVGRMGHVDSEVYLASPAVAAASAI 353
[250][TOP]
>UniRef100_C9RHV4 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
vulcanius M7 RepID=C9RHV4_9EURY
Length = 419
Score = 110 bits (276), Expect = 6e-23
Identities = 70/201 (34%), Positives = 103/201 (51%), Gaps = 9/201 (4%)
Frame = +2
Query: 2 DSVTYKYLEGKTSVPYESV---------YSDQQARFLSEYRFDVTKLEPLVAKPHSPDNR 154
D +TY YL+ + + + + + +A + E D+T +E +A PH PDN
Sbjct: 224 DEITYNYLKKERGLSDDDINKLKKERITVNKDEANYHKEVVIDITDMEEQIAVPHHPDNV 283
Query: 155 ALARECKDVKINRVYIGSCTGGKTEDFMAAAKVFLASGGKKVKVPTFLVPATQKVWMDVY 334
E I++V+IGSCT G+ ED AAK +L V ++PA++KV++
Sbjct: 284 KPVSEVAGKAIDQVFIGSCTNGRLEDLREAAK-YLKGRRVHEDVKLIVIPASKKVFLQAL 342
Query: 335 SLPVPGSGGKTCSQIFEEAGCDTPASPSCGACLGGPKDTYARMNEPQVCVSTTNRNFPGR 514
+ ++F +AG +P CG CLG + A E +VC+STTNRNF GR
Sbjct: 343 K--------EGIIEVFIKAGA-MICTPGCGPCLGAHQGVLA---EGEVCLSTTNRNFRGR 390
Query: 515 MGHREGEIYLASPYTAAASAL 577
MGH IYL+SP AA SA+
Sbjct: 391 MGHINSYIYLSSPKIAAISAV 411