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[1][TOP]
>UniRef100_B9SY83 Putative uncharacterized protein n=1 Tax=Ricinus communis
RepID=B9SY83_RICCO
Length = 455
Score = 170 bits (430), Expect = 8e-41
Identities = 84/88 (95%), Positives = 86/88 (97%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCR ALPALPISI
Sbjct: 368 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRRALPALPISI 427
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LG++FYFLTRLLMEPFIVGTATNLMMF
Sbjct: 428 TLGIIFYFLTRLLMEPFIVGTATNLMMF 455
[2][TOP]
>UniRef100_C0PF11 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C0PF11_MAIZE
Length = 479
Score = 165 bits (418), Expect = 2e-39
Identities = 80/88 (90%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+CRHALPALPISI
Sbjct: 392 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICRHALPALPISI 451
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG +TNL+MF
Sbjct: 452 MLGVTFYFLTRLLMEPFVVGASTNLVMF 479
[3][TOP]
>UniRef100_B6TCG9 Presenilin n=1 Tax=Zea mays RepID=B6TCG9_MAIZE
Length = 479
Score = 165 bits (418), Expect = 2e-39
Identities = 80/88 (90%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+CRHALPALPISI
Sbjct: 392 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICRHALPALPISI 451
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG +TNL+MF
Sbjct: 452 MLGVTFYFLTRLLMEPFVVGASTNLVMF 479
[4][TOP]
>UniRef100_UPI0001983D1C PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983D1C
Length = 448
Score = 165 bits (417), Expect = 3e-39
Identities = 81/88 (92%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVC ALPALPISI
Sbjct: 361 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCHRALPALPISI 420
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV+FYFLTRLLMEPF+VGT++NLMMF
Sbjct: 421 TLGVVFYFLTRLLMEPFVVGTSSNLMMF 448
[5][TOP]
>UniRef100_B4FNH3 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FNH3_MAIZE
Length = 478
Score = 165 bits (417), Expect = 3e-39
Identities = 79/88 (89%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAII+GLGCTL+LLS+CRHALPALPISI
Sbjct: 391 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLVLLSICRHALPALPISI 450
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG +TNL+MF
Sbjct: 451 MLGVTFYFLTRLLMEPFVVGASTNLVMF 478
[6][TOP]
>UniRef100_A7Q9Z6 Chromosome chr8 scaffold_68, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7Q9Z6_VITVI
Length = 403
Score = 165 bits (417), Expect = 3e-39
Identities = 81/88 (92%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVC ALPALPISI
Sbjct: 316 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCHRALPALPISI 375
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV+FYFLTRLLMEPF+VGT++NLMMF
Sbjct: 376 TLGVVFYFLTRLLMEPFVVGTSSNLMMF 403
[7][TOP]
>UniRef100_A5C902 Putative uncharacterized protein (Fragment) n=1 Tax=Vitis vinifera
RepID=A5C902_VITVI
Length = 414
Score = 165 bits (417), Expect = 3e-39
Identities = 81/88 (92%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVC ALPALPISI
Sbjct: 327 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCHRALPALPISI 386
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV+FYFLTRLLMEPF+VGT++NLMMF
Sbjct: 387 TLGVVFYFLTRLLMEPFVVGTSSNLMMF 414
[8][TOP]
>UniRef100_Q0JNN6 Os01g0276400 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q0JNN6_ORYSJ
Length = 351
Score = 164 bits (415), Expect = 4e-39
Identities = 78/88 (88%), Positives = 86/88 (97%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+C+HALPALPISI
Sbjct: 264 RGIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICKHALPALPISI 323
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG++TNL+MF
Sbjct: 324 LLGVTFYFLTRLLMEPFVVGSSTNLVMF 351
[9][TOP]
>UniRef100_B9EV71 Putative uncharacterized protein n=3 Tax=Oryza sativa Japonica
Group RepID=B9EV71_ORYSJ
Length = 443
Score = 164 bits (415), Expect = 4e-39
Identities = 78/88 (88%), Positives = 86/88 (97%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+C+HALPALPISI
Sbjct: 356 RGIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICKHALPALPISI 415
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG++TNL+MF
Sbjct: 416 LLGVTFYFLTRLLMEPFVVGSSTNLVMF 443
[10][TOP]
>UniRef100_B8ACI9 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=B8ACI9_ORYSI
Length = 478
Score = 164 bits (415), Expect = 4e-39
Identities = 78/88 (88%), Positives = 86/88 (97%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+C+HALPALPISI
Sbjct: 391 RGIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICKHALPALPISI 450
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG++TNL+MF
Sbjct: 451 LLGVTFYFLTRLLMEPFVVGSSTNLVMF 478
[11][TOP]
>UniRef100_C5XH90 Putative uncharacterized protein Sb03g011100 n=1 Tax=Sorghum
bicolor RepID=C5XH90_SORBI
Length = 480
Score = 164 bits (414), Expect = 6e-39
Identities = 79/88 (89%), Positives = 85/88 (96%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAII+GLGCTLILLS+C+HALPALPISI
Sbjct: 393 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIIAGLGCTLILLSICQHALPALPISI 452
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV FYFLTRLLMEPF+VG +TNL+MF
Sbjct: 453 MLGVTFYFLTRLLMEPFVVGASTNLVMF 480
[12][TOP]
>UniRef100_Q0WM47 Presenilin like protein (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q0WM47_ARATH
Length = 125
Score = 159 bits (402), Expect = 1e-37
Identities = 79/88 (89%), Positives = 82/88 (93%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSV ALPALPISI
Sbjct: 38 RGIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVYNRALPALPISI 97
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV+FYFLTRLLMEPF+VG TNLMMF
Sbjct: 98 MLGVVFYFLTRLLMEPFVVGVTTNLMMF 125
[13][TOP]
>UniRef100_O64668 Presenilin-like protein At1g08700 n=2 Tax=Arabidopsis thaliana
RepID=PSNA_ARATH
Length = 453
Score = 159 bits (402), Expect = 1e-37
Identities = 79/88 (89%), Positives = 82/88 (93%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
RGIKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSV ALPALPISI
Sbjct: 366 RGIKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVYNRALPALPISI 425
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMMF 305
LGV+FYFLTRLLMEPF+VG TNLMMF
Sbjct: 426 MLGVVFYFLTRLLMEPFVVGVTTNLMMF 453
[14][TOP]
>UniRef100_C0PSC2 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=C0PSC2_PICSI
Length = 321
Score = 139 bits (351), Expect = 1e-31
Identities = 67/86 (77%), Positives = 79/86 (91%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TLILL+ C+ ALPALP+SI+L
Sbjct: 236 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGVTLILLAFCQKALPALPVSISL 295
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FYFLTRL+ME F+V AT+L++F
Sbjct: 296 GVIFYFLTRLVMEAFVVQIATHLLLF 321
[15][TOP]
>UniRef100_A9S846 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9S846_PHYPA
Length = 477
Score = 139 bits (350), Expect = 1e-31
Identities = 67/86 (77%), Positives = 79/86 (91%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAI++GLG TLILL+V + ALPALPISI+L
Sbjct: 392 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIVAGLGATLILLAVWQRALPALPISISL 451
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FYFL RL+M+PF++ +TNL+ F
Sbjct: 452 GVIFYFLARLVMDPFVLDMSTNLVFF 477
[16][TOP]
>UniRef100_Q0WT05 Putative presenilin n=1 Tax=Arabidopsis thaliana RepID=Q0WT05_ARATH
Length = 397
Score = 135 bits (341), Expect = 2e-30
Identities = 67/86 (77%), Positives = 78/86 (90%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAII+GLG TL+LLSV + ALPALP+SI L
Sbjct: 312 IKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGITLMLLSVYQKALPALPVSIML 371
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FYFL RLL+E F+V ++NL+MF
Sbjct: 372 GVVFYFLARLLLEVFVVQCSSNLVMF 397
[17][TOP]
>UniRef100_Q9SIK7 Presenilin-like protein At2g29900 n=1 Tax=Arabidopsis thaliana
RepID=PSNB_ARATH
Length = 397
Score = 135 bits (341), Expect = 2e-30
Identities = 67/86 (77%), Positives = 78/86 (90%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYDLMTVYACYLAII+GLG TL+LLSV + ALPALP+SI L
Sbjct: 312 IKLGLGDFIFYSVLVGRAAMYDLMTVYACYLAIIAGLGITLMLLSVYQKALPALPVSIML 371
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FYFL RLL+E F+V ++NL+MF
Sbjct: 372 GVVFYFLARLLLEVFVVQCSSNLVMF 397
[18][TOP]
>UniRef100_B9N053 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9N053_POPTR
Length = 408
Score = 135 bits (340), Expect = 2e-30
Identities = 67/86 (77%), Positives = 77/86 (89%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ + ALPALP+SIAL
Sbjct: 323 IKLGLGDFIFYSVLVGRAAMYDFMTVYACYLAIIAGLGVTLMLLAFYQKALPALPVSIAL 382
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GVLFYFLTRLL+E F+V + NL+MF
Sbjct: 383 GVLFYFLTRLLLEVFVVQCSLNLVMF 408
[19][TOP]
>UniRef100_B6U914 Presenilin n=1 Tax=Zea mays RepID=B6U914_MAIZE
Length = 447
Score = 135 bits (339), Expect = 3e-30
Identities = 67/86 (77%), Positives = 76/86 (88%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ R ALPALP+SIAL
Sbjct: 362 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLAFFRKALPALPVSIAL 421
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GVLFY LTR L+E F+V +TNL+MF
Sbjct: 422 GVLFYVLTRTLLEEFVVQCSTNLVMF 447
[20][TOP]
>UniRef100_C5WT76 Putative uncharacterized protein Sb01g014990 n=1 Tax=Sorghum
bicolor RepID=C5WT76_SORBI
Length = 456
Score = 134 bits (337), Expect = 5e-30
Identities = 66/86 (76%), Positives = 76/86 (88%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ R ALPALP+SIAL
Sbjct: 371 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLAFFRKALPALPVSIAL 430
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FY LTR L+E F+V +TNL+MF
Sbjct: 431 GVVFYVLTRTLLEEFVVQCSTNLLMF 456
[21][TOP]
>UniRef100_UPI000198517B PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198517B
Length = 410
Score = 133 bits (334), Expect = 1e-29
Identities = 65/86 (75%), Positives = 75/86 (87%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL++ + ALPALP+SI L
Sbjct: 325 IKLGLGDFIFYSVLVGRAAMYDFMTVYACYLAIIAGLGVTLMLLAIYQKALPALPVSILL 384
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GVLFYF TR L+E FIV + NL+MF
Sbjct: 385 GVLFYFFTRFLLEAFIVQCSLNLLMF 410
[22][TOP]
>UniRef100_A7PDA3 Chromosome chr17 scaffold_12, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PDA3_VITVI
Length = 410
Score = 133 bits (334), Expect = 1e-29
Identities = 65/86 (75%), Positives = 75/86 (87%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL++ + ALPALP+SI L
Sbjct: 325 IKLGLGDFIFYSVLVGRAAMYDFMTVYACYLAIIAGLGVTLMLLAIYQKALPALPVSILL 384
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GVLFYF TR L+E FIV + NL+MF
Sbjct: 385 GVLFYFFTRFLLEAFIVQCSLNLLMF 410
[23][TOP]
>UniRef100_C7J054 Os03g0603700 protein n=1 Tax=Oryza sativa Japonica Group
RepID=C7J054_ORYSJ
Length = 459
Score = 132 bits (333), Expect = 1e-29
Identities = 65/86 (75%), Positives = 76/86 (88%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ R ALPALP+SIAL
Sbjct: 374 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLAFYRKALPALPVSIAL 433
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FY LTR L+E F++ +TNL+MF
Sbjct: 434 GVVFYVLTRTLLETFVMQCSTNLVMF 459
[24][TOP]
>UniRef100_A2XJB8 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2XJB8_ORYSI
Length = 458
Score = 132 bits (333), Expect = 1e-29
Identities = 65/86 (75%), Positives = 76/86 (88%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ R ALPALP+SIAL
Sbjct: 373 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLAFYRKALPALPVSIAL 432
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV+FY LTR L+E F++ +TNL+MF
Sbjct: 433 GVVFYVLTRTLLETFVMQCSTNLVMF 458
[25][TOP]
>UniRef100_A8IAG6 Presenilin protease n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IAG6_CHLRE
Length = 577
Score = 128 bits (321), Expect = 3e-28
Identities = 63/86 (73%), Positives = 73/86 (84%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYS+LVGRAAMYD MTV+A YLAII+GLG TL+ L+V + ALPALP SIAL
Sbjct: 492 IKLGLGDFIFYSMLVGRAAMYDFMTVFAAYLAIIAGLGLTLLCLAVFQKALPALPFSIAL 551
Query: 382 GVLFYFLTRLLMEPFIVGTATNLMMF 305
GV FYFLTRL +EPF++ ATNL F
Sbjct: 552 GVAFYFLTRLTLEPFLIPLATNLAFF 577
[26][TOP]
>UniRef100_B9RLN5 Putative uncharacterized protein n=1 Tax=Ricinus communis
RepID=B9RLN5_RICCO
Length = 357
Score = 104 bits (259), Expect = 5e-21
Identities = 51/63 (80%), Positives = 57/63 (90%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+ + ALPALP+SIAL
Sbjct: 265 IKLGLGDFIFYSVLVGRAAMYDFMTVYACYLAIIAGLGITLLLLAFYQKALPALPVSIAL 324
Query: 382 GVL 374
G L
Sbjct: 325 GTL 327
[27][TOP]
>UniRef100_A8X5S7 C. briggsae CBR-SEL-12 protein n=1 Tax=Caenorhabditis briggsae
RepID=A8X5S7_CAEBR
Length = 450
Score = 100 bits (249), Expect = 8e-20
Identities = 49/89 (55%), Positives = 67/89 (75%), Gaps = 1/89 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVL+G+A+ Y D T ACY+AI+ GL TL+LL+V + ALPALPIS
Sbjct: 362 RGVKLGLGDFIFYSVLLGKASSYFDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPIS 421
Query: 391 IALGVLFYFLTRLLMEPFIVGTATNLMMF 305
I G++FYF TR ++ PF+ + N ++
Sbjct: 422 IFSGLIFYFCTRWIITPFVTFVSQNSFLY 450
[28][TOP]
>UniRef100_Q5C3G2 SJCHGC02321 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5C3G2_SCHJA
Length = 286
Score = 100 bits (248), Expect = 1e-19
Identities = 48/89 (53%), Positives = 66/89 (74%), Gaps = 1/89 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+G+KLGLGDFVFYS+L+GRA + D +TV CY+AI+ G+ T+I+L + R ALPALPIS
Sbjct: 198 KGVKLGLGDFVFYSLLIGRATLDGDAVTVVTCYVAILVGMCITIIVLGITRRALPALPIS 257
Query: 391 IALGVLFYFLTRLLMEPFIVGTATNLMMF 305
IA G+LFYF++ + PF+ TA + F
Sbjct: 258 IACGILFYFVSSATISPFLEATAIERVFF 286
[29][TOP]
>UniRef100_B7FQB3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7FQB3_PHATR
Length = 297
Score = 99.8 bits (247), Expect = 1e-19
Identities = 51/81 (62%), Positives = 60/81 (74%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
I+LGLGDF+FYSVLV +AA Y T AC L I++GLG TL+LLSV ALPALPISI L
Sbjct: 212 IRLGLGDFIFYSVLVAKAAQYSFATFAACLLVILAGLGGTLVLLSVYHSALPALPISIFL 271
Query: 382 GVLFYFLTRLLMEPFIVGTAT 320
GV+FY LTR +EP+I T
Sbjct: 272 GVIFYILTRWSVEPWIEAILT 292
[30][TOP]
>UniRef100_P52166 Presenilin sel-12 n=1 Tax=Caenorhabditis elegans RepID=PSN_CAEEL
Length = 444
Score = 99.8 bits (247), Expect = 1e-19
Identities = 48/89 (53%), Positives = 67/89 (75%), Gaps = 1/89 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVL+G+A+ Y D T ACY+AI+ GL TL+LL+V + ALPALPIS
Sbjct: 356 RGVKLGLGDFIFYSVLLGKASSYFDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPIS 415
Query: 391 IALGVLFYFLTRLLMEPFIVGTATNLMMF 305
I G++FYF TR ++ PF+ + +++
Sbjct: 416 IFSGLIFYFCTRWIITPFVTQVSQKCLLY 444
[31][TOP]
>UniRef100_UPI000186D77E conserved hypothetical protein n=1 Tax=Pediculus humanus corporis
RepID=UPI000186D77E
Length = 477
Score = 98.6 bits (244), Expect = 3e-19
Identities = 48/78 (61%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL+V R ALPALPIS
Sbjct: 389 RGVKLGLGDFIFYSVLVGKASSYGDWNTTVACFVAILIGLCLTLLLLAVFRKALPALPIS 448
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++FYF T+ +++PF
Sbjct: 449 ITFGLIFYFTTKKIVKPF 466
[32][TOP]
>UniRef100_UPI00015B4AF5 PREDICTED: similar to presenilin n=1 Tax=Nasonia vitripennis
RepID=UPI00015B4AF5
Length = 500
Score = 98.6 bits (244), Expect = 3e-19
Identities = 47/78 (60%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FY VLVG+A+ Y D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 412 RGVKLGLGDFIFYGVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 471
Query: 391 IALGVLFYFLTRLLMEPF 338
IA G++FYF TR+++ PF
Sbjct: 472 IAFGLIFYFATRVIVAPF 489
[33][TOP]
>UniRef100_A9VBA9 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9VBA9_MONBE
Length = 612
Score = 98.6 bits (244), Expect = 3e-19
Identities = 47/78 (60%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAM-YDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
G+KLGLGDF+FYSVLVG+AA ++ T+ ACY+AI+ GL CTL+LLS+ + ALPALPISI
Sbjct: 525 GVKLGLGDFIFYSVLVGKAATAHEWTTILACYVAILIGLACTLLLLSIFKKALPALPISI 584
Query: 388 ALGVLFYFLTRLLMEPFI 335
G+ F+FLT +++P I
Sbjct: 585 FFGLCFFFLTSEVLDPLI 602
[34][TOP]
>UniRef100_A8PAF6 Presenilin family protein n=1 Tax=Brugia malayi RepID=A8PAF6_BRUMA
Length = 522
Score = 98.6 bits (244), Expect = 3e-19
Identities = 51/89 (57%), Positives = 66/89 (74%), Gaps = 1/89 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+GIKLGLGDF+FYSVLVG+A+ Y D T ACY+AI+ GL TLILL+V R ALPALPIS
Sbjct: 434 KGIKLGLGDFIFYSVLVGKASSYGDWNTTVACYVAILIGLCFTLILLAVFRKALPALPIS 493
Query: 391 IALGVLFYFLTRLLMEPFIVGTATNLMMF 305
I G++FYF TR ++ PF + +++
Sbjct: 494 IFCGLIFYFCTRGIITPFCTSLSLRHLIY 522
[35][TOP]
>UniRef100_UPI0001792531 PREDICTED: similar to Presenilin CG18803-PB n=1 Tax=Acyrthosiphon
pisum RepID=UPI0001792531
Length = 376
Score = 98.2 bits (243), Expect = 4e-19
Identities = 48/78 (61%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+G+KLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 288 KGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFRRALPALPIS 347
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++FYF TR L++PF
Sbjct: 348 ITFGLVFYFATRGLVKPF 365
[36][TOP]
>UniRef100_C0SKM6 Presenilin n=1 Tax=Schistosoma mansoni RepID=C0SKM6_SCHMA
Length = 494
Score = 98.2 bits (243), Expect = 4e-19
Identities = 47/89 (52%), Positives = 65/89 (73%), Gaps = 1/89 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+G+KLGLGDFVFYS+L+GRA + D +TV CY+AI+ G+ T+I+L + R ALPALPIS
Sbjct: 406 KGVKLGLGDFVFYSLLIGRATLDGDAVTVVTCYVAILVGMCITVIVLGITRQALPALPIS 465
Query: 391 IALGVLFYFLTRLLMEPFIVGTATNLMMF 305
I G+LFYF++ + PF+ TA + F
Sbjct: 466 ITCGILFYFVSSATISPFLEATAIERVFF 494
[37][TOP]
>UniRef100_UPI0000DB7033 PREDICTED: similar to Presenilin CG18803-PB, isoform B n=1 Tax=Apis
mellifera RepID=UPI0000DB7033
Length = 500
Score = 97.1 bits (240), Expect = 9e-19
Identities = 46/78 (58%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 412 RGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 471
Query: 391 IALGVLFYFLTRLLMEPF 338
+ G+ FYF TR+++ PF
Sbjct: 472 VTFGLTFYFATRVIVAPF 489
[38][TOP]
>UniRef100_B7Q2V0 Presenilin, putative (Fragment) n=1 Tax=Ixodes scapularis
RepID=B7Q2V0_IXOSC
Length = 431
Score = 97.1 bits (240), Expect = 9e-19
Identities = 47/78 (60%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 343 RGVKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPIS 402
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++FYF T L++PF
Sbjct: 403 ITFGLIFYFATSSLVQPF 420
[39][TOP]
>UniRef100_C4QD74 Subfamily A22A unassigned peptidase (A22 family) n=1
Tax=Schistosoma mansoni RepID=C4QD74_SCHMA
Length = 501
Score = 96.7 bits (239), Expect = 1e-18
Identities = 46/83 (55%), Positives = 63/83 (75%), Gaps = 1/83 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+G+KLGLGDFVFYS+L+GRA + D +TV CY+AI+ G+ T+I+L + R ALPALPIS
Sbjct: 406 KGVKLGLGDFVFYSLLIGRATLDGDAVTVVTCYVAILVGMCITVIVLGITRQALPALPIS 465
Query: 391 IALGVLFYFLTRLLMEPFIVGTA 323
I G+LFYF++ + PF+ TA
Sbjct: 466 ITCGILFYFVSSATISPFLEATA 488
[40][TOP]
>UniRef100_B4KY37 GI13394 n=1 Tax=Drosophila mojavensis RepID=B4KY37_DROMO
Length = 546
Score = 96.7 bits (239), Expect = 1e-18
Identities = 48/79 (60%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 458 RGIKLGLGDFIFYSVLVGKASTYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 517
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T L++PF+
Sbjct: 518 ITFGLIFCFATNFLVKPFM 536
[41][TOP]
>UniRef100_UPI00017585CF PREDICTED: similar to Presenilin CG18803-PB isoform 1 n=1
Tax=Tribolium castaneum RepID=UPI00017585CF
Length = 463
Score = 96.3 bits (238), Expect = 1e-18
Identities = 46/78 (58%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 375 RGVKLGLGDFIFYSVLVGKASSYGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 434
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++FYF T+ ++ PF
Sbjct: 435 ITFGLIFYFATKEIVSPF 452
[42][TOP]
>UniRef100_C1DYR1 Presenilin ER Ca2+ leak channel family n=1 Tax=Micromonas sp.
RCC299 RepID=C1DYR1_9CHLO
Length = 392
Score = 95.9 bits (237), Expect = 2e-18
Identities = 49/84 (58%), Positives = 60/84 (71%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLV RAA+YD +C+LA++ GL TL LL V ALPALPISIA
Sbjct: 306 IKLGLGDFIFYSVLVARAALYDTFVATSCFLAVLQGLVGTLFLLGVYERALPALPISIAF 365
Query: 382 GVLFYFLTRLLMEPFIVGTATNLM 311
GVL YF +R +EP + A+ L+
Sbjct: 366 GVLAYFGSRYALEPVAMEFASQLV 389
[43][TOP]
>UniRef100_B4N6M7 GK12343 n=1 Tax=Drosophila willistoni RepID=B4N6M7_DROWI
Length = 541
Score = 95.5 bits (236), Expect = 2e-18
Identities = 47/79 (59%), Positives = 63/79 (79%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 453 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 512
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T ++++PF+
Sbjct: 513 ITFGLIFCFATSVVVKPFM 531
[44][TOP]
>UniRef100_B7FQB4 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
1055/1 RepID=B7FQB4_PHATR
Length = 252
Score = 95.1 bits (235), Expect = 3e-18
Identities = 46/76 (60%), Positives = 60/76 (78%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYS+LV +AA+Y T A LAI++GLG TL+LL++ ALPALPISI L
Sbjct: 167 IKLGLGDFIFYSILVSKAAIYSFATFAASSLAILAGLGLTLLLLAIRGQALPALPISIFL 226
Query: 382 GVLFYFLTRLLMEPFI 335
GV+FY TR ++EP++
Sbjct: 227 GVVFYLTTRYVLEPWV 242
[45][TOP]
>UniRef100_B4LGD3 GJ11519 n=1 Tax=Drosophila virilis RepID=B4LGD3_DROVI
Length = 532
Score = 95.1 bits (235), Expect = 3e-18
Identities = 48/79 (60%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL+V R ALPALPIS
Sbjct: 444 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAVWRKALPALPIS 503
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 504 ITFGLIFCFATSAVVKPFM 522
[46][TOP]
>UniRef100_Q29DD6 GA15086 n=2 Tax=pseudoobscura subgroup RepID=Q29DD6_DROPS
Length = 531
Score = 95.1 bits (235), Expect = 3e-18
Identities = 48/79 (60%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL+V R ALPALPIS
Sbjct: 443 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAVWRKALPALPIS 502
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 503 ITFGLIFCFATSAVVKPFM 521
[47][TOP]
>UniRef100_Q010E4 A84702 probable presenilin (ISS) (Fragment) n=1 Tax=Ostreococcus
tauri RepID=Q010E4_OSTTA
Length = 567
Score = 94.7 bits (234), Expect = 4e-18
Identities = 49/77 (63%), Positives = 59/77 (76%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYS+LVGRAAM+ +T C++A+ISGL TL LSV ALPALPISIAL
Sbjct: 334 IKLGLGDFIFYSLLVGRAAMWSWITCAFCFIAVISGLVLTLFALSVHGKALPALPISIAL 393
Query: 382 GVLFYFLTRLLMEPFIV 332
G YFL+ +EP+IV
Sbjct: 394 GAATYFLSSRFVEPWIV 410
[48][TOP]
>UniRef100_B7Z090 Presenilin, isoform C n=2 Tax=Drosophila melanogaster
RepID=B7Z090_DROME
Length = 508
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 420 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 479
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 480 ITFGLIFCFATSAVVKPFM 498
[49][TOP]
>UniRef100_B4QRZ4 GD14885 n=1 Tax=Drosophila simulans RepID=B4QRZ4_DROSI
Length = 527
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 439 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 498
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 499 ITFGLIFCFATSAVVKPFM 517
[50][TOP]
>UniRef100_B4IZ02 GH14546 n=1 Tax=Drosophila grimshawi RepID=B4IZ02_DROGR
Length = 536
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 448 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 507
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 508 ITFGLIFCFATSAVVKPFM 526
[51][TOP]
>UniRef100_B4IUG4 GE23235 n=1 Tax=Drosophila yakuba RepID=B4IUG4_DROYA
Length = 524
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 436 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 495
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 496 ITFGLIFCFATSAVVKPFM 514
[52][TOP]
>UniRef100_B4IAA8 GM22291 n=1 Tax=Drosophila sechellia RepID=B4IAA8_DROSE
Length = 527
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 439 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 498
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 499 ITFGLIFCFATSAVVKPFM 517
[53][TOP]
>UniRef100_B3NIM0 GG16113 n=1 Tax=Drosophila erecta RepID=B3NIM0_DROER
Length = 522
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 434 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 493
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 494 ITFGLIFCFATSAVVKPFM 512
[54][TOP]
>UniRef100_B3M997 GF10339 n=1 Tax=Drosophila ananassae RepID=B3M997_DROAN
Length = 531
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 443 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 502
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 503 ITFGLIFCFATSAVVKPFM 521
[55][TOP]
>UniRef100_B0WS38 Presenilin sel-12 n=1 Tax=Culex quinquefasciatus RepID=B0WS38_CULQU
Length = 526
Score = 94.7 bits (234), Expect = 4e-18
Identities = 48/84 (57%), Positives = 64/84 (76%), Gaps = 1/84 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 438 RGIKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILVGLCLTLLLLAIFRKALPALPIS 497
Query: 391 IALGVLFYFLTRLLMEPFIVGTAT 320
I G++F F T ++++PF A+
Sbjct: 498 IFFGLIFCFATSVIVKPFTEALAS 521
[56][TOP]
>UniRef100_O02194-2 Isoform 2 of Presenilin homolog n=1 Tax=Drosophila melanogaster
RepID=O02194-2
Length = 527
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 439 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 498
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 499 ITFGLIFCFATSAVVKPFM 517
[57][TOP]
>UniRef100_O02194 Presenilin homolog n=1 Tax=Drosophila melanogaster RepID=PSN_DROME
Length = 541
Score = 94.7 bits (234), Expect = 4e-18
Identities = 47/79 (59%), Positives = 62/79 (78%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RGIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPIS
Sbjct: 453 RGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPIS 512
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++F F T +++PF+
Sbjct: 513 ITFGLIFCFATSAVVKPFM 531
[58][TOP]
>UniRef100_UPI0000E46566 PREDICTED: similar to presenilin n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E46566
Length = 480
Score = 94.4 bits (233), Expect = 6e-18
Identities = 49/78 (62%), Positives = 61/78 (78%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA-AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TLILL++ + ALPALPIS
Sbjct: 392 RGVKLGLGDFIFYSVLVGKASASGDWTTTIACFVAILIGLCLTLILLAIFKKALPALPIS 451
Query: 391 IALGVLFYFLTRLLMEPF 338
IA G++FYF T L+ PF
Sbjct: 452 IAFGLVFYFCTSNLVFPF 469
[59][TOP]
>UniRef100_UPI0000E46565 PREDICTED: similar to presenilin n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E46565
Length = 518
Score = 94.4 bits (233), Expect = 6e-18
Identities = 49/78 (62%), Positives = 61/78 (78%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA-AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TLILL++ + ALPALPIS
Sbjct: 430 RGVKLGLGDFIFYSVLVGKASASGDWTTTIACFVAILIGLCLTLILLAIFKKALPALPIS 489
Query: 391 IALGVLFYFLTRLLMEPF 338
IA G++FYF T L+ PF
Sbjct: 490 IAFGLVFYFCTSNLVFPF 507
[60][TOP]
>UniRef100_UPI0000584360 PREDICTED: similar to presenilin isoform 3 n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000584360
Length = 478
Score = 94.4 bits (233), Expect = 6e-18
Identities = 49/78 (62%), Positives = 61/78 (78%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA-AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TLILL++ + ALPALPIS
Sbjct: 390 RGVKLGLGDFIFYSVLVGKASASGDWTTTIACFVAILIGLCLTLILLAIFKKALPALPIS 449
Query: 391 IALGVLFYFLTRLLMEPF 338
IA G++FYF T L+ PF
Sbjct: 450 IAFGLVFYFCTSNLVFPF 467
[61][TOP]
>UniRef100_Q6P0Y0 Presenilin2 n=1 Tax=Danio rerio RepID=Q6P0Y0_DANRE
Length = 441
Score = 94.0 bits (232), Expect = 7e-18
Identities = 48/86 (55%), Positives = 64/86 (74%), Gaps = 2/86 (2%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
RG+KLGLGDF+FYSVLVG+AA D T+ AC++AI+ GL TL+LL++ + ALPALPI
Sbjct: 352 RGVKLGLGDFIFYSVLVGKAAATGGDWNTILACFVAILIGLCLTLLLLAIFKKALPALPI 411
Query: 394 SIALGVLFYFLTRLLMEPFIVGTATN 317
SI G++FYF T L+ PF+ A +
Sbjct: 412 SITFGLVFYFSTDNLVRPFMDSLAAH 437
[62][TOP]
>UniRef100_P97887 Presenilin-1 CTF12 n=1 Tax=Rattus norvegicus RepID=PSN1_RAT
Length = 468
Score = 94.0 bits (232), Expect = 7e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 378 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 437
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 438 ISITFGLIFYFATDYLVQPFM 458
[63][TOP]
>UniRef100_P79802-2 Isoform I-463 of Presenilin-1 n=1 Tax=Microcebus murinus
RepID=P79802-2
Length = 463
Score = 94.0 bits (232), Expect = 7e-18
Identities = 48/81 (59%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDFVFYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 373 RGVKLGLGDFVFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 432
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 433 ISITFGLVFYFATDYLVQPFM 453
[64][TOP]
>UniRef100_P79802 Presenilin-1 CTF12 n=1 Tax=Microcebus murinus RepID=PSN1_MICMU
Length = 467
Score = 94.0 bits (232), Expect = 7e-18
Identities = 48/81 (59%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDFVFYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFVFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDYLVQPFM 457
[65][TOP]
>UniRef100_UPI00015604AB PREDICTED: similar to presenilin 1 n=1 Tax=Equus caballus
RepID=UPI00015604AB
Length = 470
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 380 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 439
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 440 ISITFGLVFYFATDYLVQPFM 460
[66][TOP]
>UniRef100_UPI0000E239A7 PREDICTED: presenilin 1 isoform 6 n=1 Tax=Pan troglodytes
RepID=UPI0000E239A7
Length = 443
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 353 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 412
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 413 ISITFGLVFYFATDYLVQPFM 433
[67][TOP]
>UniRef100_UPI0000D9BCD2 PREDICTED: presenilin 1 (Alzheimer disease 3) isoform 3 n=1
Tax=Macaca mulatta RepID=UPI0000D9BCD2
Length = 436
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 346 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 405
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 406 ISITFGLVFYFATDYLVQPFM 426
[68][TOP]
>UniRef100_UPI0000D9BCD1 PREDICTED: presenilin 1 (Alzheimer disease 3) isoform 4 n=1
Tax=Macaca mulatta RepID=UPI0000D9BCD1
Length = 436
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 346 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 405
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 406 ISITFGLVFYFATDYLVQPFM 426
[69][TOP]
>UniRef100_UPI00005E89A6 PREDICTED: similar to presenilin 1 n=1 Tax=Monodelphis domestica
RepID=UPI00005E89A6
Length = 471
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 381 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 440
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 441 ISITFGLVFYFATDYLVQPFM 461
[70][TOP]
>UniRef100_Q6P2Y8 Presenilin 1 n=2 Tax=Xenopus (Silurana) tropicalis
RepID=Q6P2Y8_XENTR
Length = 433
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 343 RGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 402
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 403 ISITFGLVFYFATDYLVQPFM 423
[71][TOP]
>UniRef100_UPI0001611370 UPI0001611370 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001611370
Length = 375
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 285 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 344
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 345 ISITFGLVFYFATDYLVQPFM 365
[72][TOP]
>UniRef100_UPI0000EB2F47 Presenilin-1 (EC 3.4.23.-) (PS-1) [Contains: Presenilin-1 NTF
subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12
(PS1-CTF12)]. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB2F47
Length = 468
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 378 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 437
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 438 ISITFGLVFYFATDYLVQPFM 458
[73][TOP]
>UniRef100_UPI00004C0F38 Presenilin-1 (EC 3.4.23.-) (PS-1) [Contains: Presenilin-1 NTF
subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12
(PS1-CTF12)]. n=1 Tax=Canis lupus familiaris
RepID=UPI00004C0F38
Length = 466
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 376 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 435
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 436 ISITFGLVFYFATDYLVQPFM 456
[74][TOP]
>UniRef100_Q5EM20 Presenilin 2 (Fragment) n=1 Tax=Mus musculus RepID=Q5EM20_MOUSE
Length = 260
Score = 93.6 bits (231), Expect = 9e-18
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 170 RGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALP 229
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 230 ISITFGLIFYFSTDSLVRPFM 250
[75][TOP]
>UniRef100_Q3TDW2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3TDW2_MOUSE
Length = 339
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 249 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 308
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 309 ISITFGLVFYFATDYLVQPFM 329
[76][TOP]
>UniRef100_Q0MS44 Presenilin 1 n=1 Tax=Sus scrofa RepID=Q0MS44_PIG
Length = 467
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDYLVQPFM 457
[77][TOP]
>UniRef100_A7MBA9 PSEN1 protein n=1 Tax=Bos taurus RepID=A7MBA9_BOVIN
Length = 468
Score = 93.6 bits (231), Expect = 9e-18
Identities = 46/81 (56%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 378 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 437
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
+SI G++FYF T L++PF+
Sbjct: 438 VSITFGLIFYFATDYLVQPFM 458
[78][TOP]
>UniRef100_Q53FV8 Presenilin 1 isoform I-463 variant (Fragment) n=1 Tax=Homo sapiens
RepID=Q53FV8_HUMAN
Length = 463
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 373 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 432
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 433 ISITFGLVFYFATDYLVQPFM 453
[79][TOP]
>UniRef100_B7Z8T5 cDNA FLJ53003, highly similar to Presenilin-1 (EC 3.4.23.-) n=1
Tax=Homo sapiens RepID=B7Z8T5_HUMAN
Length = 264
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 174 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 233
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 234 ISITFGLVFYFATDYLVQPFM 254
[80][TOP]
>UniRef100_O88777 Presenilin-2 CTF subunit n=1 Tax=Rattus norvegicus RepID=PSN2_RAT
Length = 448
Score = 93.6 bits (231), Expect = 9e-18
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[81][TOP]
>UniRef100_O12976 Presenilin-1 n=1 Tax=Xenopus laevis RepID=PSN1_XENLA
Length = 433
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 343 RGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 402
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 403 ISITFGLVFYFATDYLVQPFM 423
[82][TOP]
>UniRef100_Q5R780-2 Isoform I-463 of Presenilin-1 n=1 Tax=Pongo abelii RepID=Q5R780-2
Length = 463
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 373 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 432
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 433 ISITFGLVFYFATDYLVQPFM 453
[83][TOP]
>UniRef100_Q5R780 Presenilin-1 CTF12 n=1 Tax=Pongo abelii RepID=PSN1_PONAB
Length = 467
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDYLVQPFM 457
[84][TOP]
>UniRef100_P49769 Presenilin-1 CTF12 n=2 Tax=Mus musculus RepID=PSN1_MOUSE
Length = 467
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDYLVQPFM 457
[85][TOP]
>UniRef100_P49768-2 Isoform 2 of Presenilin-1 n=2 Tax=Catarrhini RepID=P49768-2
Length = 463
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 373 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 432
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 433 ISITFGLVFYFATDYLVQPFM 453
[86][TOP]
>UniRef100_P49768-6 Isoform 6 of Presenilin-1 n=1 Tax=Homo sapiens RepID=P49768-6
Length = 409
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 319 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 378
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 379 ISITFGLVFYFATDYLVQPFM 399
[87][TOP]
>UniRef100_P49768 Presenilin-1 CTF12 n=2 Tax=Homo sapiens RepID=PSN1_HUMAN
Length = 467
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDYLVQPFM 457
[88][TOP]
>UniRef100_Q6RH31-2 Isoform I-462 of Presenilin-1 n=1 Tax=Canis lupus familiaris
RepID=Q6RH31-2
Length = 462
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 372 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 431
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 432 ISITFGLVFYFATDYLVQPFM 452
[89][TOP]
>UniRef100_Q6RH31 Presenilin-1 CTF12 n=1 Tax=Canis lupus familiaris RepID=PSN1_CANFA
Length = 466
Score = 93.6 bits (231), Expect = 9e-18
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 376 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 435
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 436 ISITFGLVFYFATDYLVQPFM 456
[90][TOP]
>UniRef100_Q9XT97 Presenilin-1 CTF12 n=1 Tax=Bos taurus RepID=PSN1_BOVIN
Length = 478
Score = 93.6 bits (231), Expect = 9e-18
Identities = 46/81 (56%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 388 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 447
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
+SI G++FYF T L++PF+
Sbjct: 448 VSITFGLIFYFATDYLVQPFM 468
[91][TOP]
>UniRef100_UPI000069D99D UPI000069D99D related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069D99D
Length = 451
Score = 93.2 bits (230), Expect = 1e-17
Identities = 49/89 (55%), Positives = 65/89 (73%), Gaps = 3/89 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 361 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 420
Query: 397 ISIALGVLFYFLTRLLMEPFIVGTATNLM 311
ISI G++FYF T ++ PF+ A++ M
Sbjct: 421 ISITFGLIFYFSTDNIVRPFMDTLASHQM 449
[92][TOP]
>UniRef100_UPI00016E4EB5 UPI00016E4EB5 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB5
Length = 436
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 348 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 407
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 408 ITFGLIFYFSTDFLVQPFMDNLAAH 432
[93][TOP]
>UniRef100_UPI00016E4EB4 UPI00016E4EB4 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB4
Length = 444
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 356 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 415
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 416 ITFGLIFYFSTDFLVQPFMDNLAAH 440
[94][TOP]
>UniRef100_UPI00016E4EB3 UPI00016E4EB3 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB3
Length = 417
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 329 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 388
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 389 ITFGLIFYFSTDFLVQPFMDNLAAH 413
[95][TOP]
>UniRef100_UPI00016E4EB2 UPI00016E4EB2 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB2
Length = 422
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 334 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 393
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 394 ITFGLIFYFSTDFLVQPFMDNLAAH 418
[96][TOP]
>UniRef100_UPI00016E4EB1 UPI00016E4EB1 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB1
Length = 423
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 335 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 394
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 395 ITFGLIFYFSTDFLVQPFMDNLAAH 419
[97][TOP]
>UniRef100_UPI00016E4EB0 UPI00016E4EB0 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E4EB0
Length = 406
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/85 (55%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 318 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 377
Query: 391 IALGVLFYFLTRLLMEPFIVGTATN 317
I G++FYF T L++PF+ A +
Sbjct: 378 ITFGLIFYFSTDFLVQPFMDNLAAH 402
[98][TOP]
>UniRef100_Q28HZ1 Presenilin 2 (Alzheimer disease 4) n=1 Tax=Xenopus (Silurana)
tropicalis RepID=Q28HZ1_XENTR
Length = 451
Score = 93.2 bits (230), Expect = 1e-17
Identities = 49/89 (55%), Positives = 65/89 (73%), Gaps = 3/89 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 361 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 420
Query: 397 ISIALGVLFYFLTRLLMEPFIVGTATNLM 311
ISI G++FYF T ++ PF+ A++ M
Sbjct: 421 ISITFGLIFYFSTDNIVRPFMDTLASHQM 449
[99][TOP]
>UniRef100_Q3U4P5 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q3U4P5_MOUSE
Length = 448
Score = 93.2 bits (230), Expect = 1e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[100][TOP]
>UniRef100_B8C3Y7 Presenilin n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8C3Y7_THAPS
Length = 369
Score = 93.2 bits (230), Expect = 1e-17
Identities = 47/76 (61%), Positives = 58/76 (76%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLV +AA AC+L+I++GLG TL+LL+V HALPALPISI L
Sbjct: 284 IKLGLGDFIFYSVLVSKAAENGFAAFVACFLSILTGLGGTLVLLAVYHHALPALPISIFL 343
Query: 382 GVLFYFLTRLLMEPFI 335
V+F+ LT MEP+I
Sbjct: 344 AVVFFVLTIYCMEPWI 359
[101][TOP]
>UniRef100_Q9GU38 Presenilin n=1 Tax=Helix lucorum RepID=Q9GU38_HELLU
Length = 582
Score = 93.2 bits (230), Expect = 1e-17
Identities = 46/84 (54%), Positives = 63/84 (75%), Gaps = 1/84 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FY VLVG+A+ D T AC++AI+ GL CTL+LL++ R ALPALPIS
Sbjct: 494 RGVKLGLGDFIFYGVLVGKASSNGDWNTTLACFVAILIGLCCTLLLLAIFRKALPALPIS 553
Query: 391 IALGVLFYFLTRLLMEPFIVGTAT 320
+ G++F F T L++PF+ A+
Sbjct: 554 LTFGLVFNFATSSLVQPFMDSLAS 577
[102][TOP]
>UniRef100_Q7PR98 AGAP002957-PA (Fragment) n=1 Tax=Anopheles gambiae
RepID=Q7PR98_ANOGA
Length = 456
Score = 93.2 bits (230), Expect = 1e-17
Identities = 46/77 (59%), Positives = 62/77 (80%), Gaps = 1/77 (1%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
GIKLGLGDF+FYSVLVG+A+ Y D T AC++AI+ GL TL+LL++ R ALPALPISI
Sbjct: 369 GIKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILVGLCLTLLLLAIFRKALPALPISI 428
Query: 388 ALGVLFYFLTRLLMEPF 338
G++F F+T ++++PF
Sbjct: 429 FFGLIFCFVTSVIVKPF 445
[103][TOP]
>UniRef100_O12977 Presenilin-2 n=1 Tax=Xenopus laevis RepID=PSN2_XENLA
Length = 449
Score = 93.2 bits (230), Expect = 1e-17
Identities = 49/89 (55%), Positives = 65/89 (73%), Gaps = 3/89 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 359 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 418
Query: 397 ISIALGVLFYFLTRLLMEPFIVGTATNLM 311
ISI G++FYF T ++ PF+ A++ M
Sbjct: 419 ISITFGLIFYFSTDNIVRPFMDTLASHQM 447
[104][TOP]
>UniRef100_Q61144 Presenilin-2 CTF subunit n=1 Tax=Mus musculus RepID=PSN2_MOUSE
Length = 448
Score = 93.2 bits (230), Expect = 1e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[105][TOP]
>UniRef100_UPI000194C58A PREDICTED: presenilin 1 (Alzheimer disease 3) n=1 Tax=Taeniopygia
guttata RepID=UPI000194C58A
Length = 467
Score = 92.8 bits (229), Expect = 2e-17
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISITFGLVFYFATDNLVQPFM 457
[106][TOP]
>UniRef100_UPI000194BE69 PREDICTED: presenilin 2 (Alzheimer disease 4) n=1 Tax=Taeniopygia
guttata RepID=UPI000194BE69
Length = 458
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 368 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 427
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 428 ISITFGLIFYFSTDNLVRPFM 448
[107][TOP]
>UniRef100_UPI000155D36B PREDICTED: similar to presenilin 2 (Alzheimer disease 4) n=1
Tax=Ornithorhynchus anatinus RepID=UPI000155D36B
Length = 455
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 365 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 424
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 425 ISITFGLIFYFSTDNLVRPFM 445
[108][TOP]
>UniRef100_UPI000155C2B6 PREDICTED: similar to presenilin 1 n=1 Tax=Ornithorhynchus anatinus
RepID=UPI000155C2B6
Length = 336
Score = 92.8 bits (229), Expect = 2e-17
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 246 RGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 305
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 306 ISITFGLVFYFATDNLVQPFM 326
[109][TOP]
>UniRef100_UPI0000F2BE65 PREDICTED: similar to presenilin 2 n=1 Tax=Monodelphis domestica
RepID=UPI0000F2BE65
Length = 426
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 336 RGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 395
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 396 ISITFGLIFYFSTDNLVRPFM 416
[110][TOP]
>UniRef100_UPI0000E1F03F PREDICTED: presenilin 2 isoform 2 n=1 Tax=Pan troglodytes
RepID=UPI0000E1F03F
Length = 448
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[111][TOP]
>UniRef100_UPI0000D99CFB PREDICTED: presenilin 2 n=1 Tax=Macaca mulatta RepID=UPI0000D99CFB
Length = 654
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 564 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 623
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 624 ISITFGLIFYFSTDNLVRPFM 644
[112][TOP]
>UniRef100_UPI00005A14BD PREDICTED: similar to Presenilin 2 (PS-2) (STM-2) (E5-1) (AD3LP)
(AD5) n=1 Tax=Canis lupus familiaris RepID=UPI00005A14BD
Length = 717
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 627 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 686
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 687 ISITFGLIFYFSTDNLVRPFM 707
[113][TOP]
>UniRef100_UPI0000EB3683 Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5)
[Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF
subunit]. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3683
Length = 455
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 365 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 424
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 425 ISITFGLIFYFSTDNLVRPFM 445
[114][TOP]
>UniRef100_UPI0000ECC987 Presenilin-2 (EC 3.4.23.-) (PS-2) [Contains: Presenilin-2 NTF
subunit; Presenilin-2 CTF subunit]. n=2 Tax=Gallus
gallus RepID=UPI0000ECC987
Length = 456
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 366 RGVKLGLGDFIFYSVLVGKAAATPSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 425
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 426 ISITFGLIFYFSTDNLVRPFM 446
[115][TOP]
>UniRef100_Q5QHS2 Presenilin 2 n=1 Tax=Gallus gallus RepID=Q5QHS2_CHICK
Length = 456
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 366 RGVKLGLGDFIFYSVLVGKAAATPSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 425
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 426 ISITFGLIFYFSTDNLVRPFM 446
[116][TOP]
>UniRef100_B5X1U6 Presenilin-2 n=1 Tax=Salmo salar RepID=B5X1U6_SALSA
Length = 447
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/86 (55%), Positives = 63/86 (73%), Gaps = 2/86 (2%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPI
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPI 417
Query: 394 SIALGVLFYFLTRLLMEPFIVGTATN 317
SI G++FYF T L+ PF+ A +
Sbjct: 418 SITFGLVFYFSTDNLVRPFMDNLAAH 443
[117][TOP]
>UniRef100_C9J5P7 Putative uncharacterized protein PSEN2 n=1 Tax=Homo sapiens
RepID=C9J5P7_HUMAN
Length = 415
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 325 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 384
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 385 ISITFGLIFYFSTDNLVRPFM 405
[118][TOP]
>UniRef100_B4DVM3 cDNA FLJ51336, highly similar to Presenilin-2 (EC 3.4.23.-) n=1
Tax=Homo sapiens RepID=B4DVM3_HUMAN
Length = 359
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 269 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 328
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 329 ISITFGLIFYFSTDNLVRPFM 349
[119][TOP]
>UniRef100_P49810 Presenilin-2 CTF subunit n=2 Tax=Homo sapiens RepID=PSN2_HUMAN
Length = 448
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[120][TOP]
>UniRef100_A8K8D4 cDNA FLJ77434, highly similar to Homo sapiens presenilin 2
(Alzheimer disease 4) (PSEN2), transcript variant 2,
mRNA n=1 Tax=Homo sapiens RepID=A8K8D4_HUMAN
Length = 447
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 357 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 416
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 417 ISITFGLIFYFSTDNLVRPFM 437
[121][TOP]
>UniRef100_Q5RCN9 Presenilin-2 CTF subunit n=1 Tax=Pongo abelii RepID=PSN2_PONAB
Length = 448
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[122][TOP]
>UniRef100_Q0MS45 Presenilin-2 CTF subunit n=1 Tax=Sus scrofa RepID=PSN2_PIG
Length = 448
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLIFYFSTDNLVRPFM 438
[123][TOP]
>UniRef100_P49810-2 Isoform 2 of Presenilin-2 n=1 Tax=Homo sapiens RepID=P49810-2
Length = 414
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 324 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 383
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 384 ISITFGLIFYFSTDNLVRPFM 404
[124][TOP]
>UniRef100_Q90ZE4 Presenilin-2 n=2 Tax=Danio rerio RepID=PSN2_DANRE
Length = 441
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/86 (55%), Positives = 63/86 (73%), Gaps = 2/86 (2%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPI
Sbjct: 352 RGVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPI 411
Query: 394 SIALGVLFYFLTRLLMEPFIVGTATN 317
SI G++FYF T L+ PF+ A +
Sbjct: 412 SITFGLVFYFSTDNLVRPFMDSLAAH 437
[125][TOP]
>UniRef100_Q9XT96 Presenilin-2 CTF subunit n=1 Tax=Bos taurus RepID=PSN2_BOVIN
Length = 449
Score = 92.8 bits (229), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 359 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 418
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 419 ISITFGLIFYFSTDNLVRPFM 439
[126][TOP]
>UniRef100_Q4JIM4 Presenilin-1 CTF subunit n=1 Tax=Gallus gallus RepID=PSN1_CHICK
Length = 468
Score = 92.8 bits (229), Expect = 2e-17
Identities = 47/81 (58%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 378 RGVKLGLGDFIFYSVLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 437
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 438 ISITFGLVFYFATDNLVQPFM 458
[127][TOP]
>UniRef100_UPI0001560B2C PREDICTED: similar to presenilin 2 n=1 Tax=Equus caballus
RepID=UPI0001560B2C
Length = 448
Score = 92.4 bits (228), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLVFYFSTDNLVRPFM 438
[128][TOP]
>UniRef100_UPI00017B4CF6 UPI00017B4CF6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4CF6
Length = 416
Score = 92.4 bits (228), Expect = 2e-17
Identities = 46/79 (58%), Positives = 61/79 (77%), Gaps = 2/79 (2%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 328 GVKLGLGDFIFYSVLVGKAAATGGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 387
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++FYF T L++PF+
Sbjct: 388 ITFGLVFYFSTDFLVQPFM 406
[129][TOP]
>UniRef100_A4S3L3 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S3L3_OSTLU
Length = 353
Score = 92.4 bits (228), Expect = 2e-17
Identities = 46/77 (59%), Positives = 58/77 (75%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLVGRAAM+ +T C++A++ GL TL+ L + ALPALP+SIAL
Sbjct: 267 IKLGLGDFIFYSVLVGRAAMWSPITCAFCFIAVLLGLVLTLVALGMYGKALPALPVSIAL 326
Query: 382 GVLFYFLTRLLMEPFIV 332
G YFL+R +EP IV
Sbjct: 327 GSATYFLSRFFLEPAIV 343
[130][TOP]
>UniRef100_P79801 Presenilin-2 CTF subunit (Fragment) n=1 Tax=Microcebus murinus
RepID=PSN2_MICMU
Length = 445
Score = 92.4 bits (228), Expect = 2e-17
Identities = 48/81 (59%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALP
Sbjct: 358 RGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALP 417
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 418 ISITFGLVFYFSTDNLVRPFM 438
[131][TOP]
>UniRef100_B8BVL0 Presenilin (Fragment) n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8BVL0_THAPS
Length = 372
Score = 92.0 bits (227), Expect = 3e-17
Identities = 43/75 (57%), Positives = 57/75 (76%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
IKLGLGDF+FYSVLV ++A Y + +L +++GLG TL+LL+V +HALPALPISI L
Sbjct: 298 IKLGLGDFIFYSVLVAKSAQYSFACFVSSFLVVLAGLGGTLVLLAVFKHALPALPISIFL 357
Query: 382 GVLFYFLTRLLMEPF 338
V FY TR ++EP+
Sbjct: 358 AVTFYVFTRFIIEPW 372
[132][TOP]
>UniRef100_C4M1A2 Presenilin 1 peptidase, putative n=1 Tax=Entamoeba histolytica
HM-1:IMSS RepID=C4M1A2_ENTHI
Length = 396
Score = 92.0 bits (227), Expect = 3e-17
Identities = 50/85 (58%), Positives = 61/85 (71%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
+G+KLGLGDFVFYSVLVGR AMYDL V++ +A++SGL TLILL V ALPALPISI
Sbjct: 309 KGVKLGLGDFVFYSVLVGRCAMYDLTIVFSGSVAVLSGLFGTLILLVVFNKALPALPISI 368
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNL 314
G L Y ++R + P + T NL
Sbjct: 369 FFGTLIYCVSRWAIVPLV--TTANL 391
[133][TOP]
>UniRef100_B0E9S5 Presenilin hop-1, putative n=1 Tax=Entamoeba dispar SAW760
RepID=B0E9S5_ENTDI
Length = 233
Score = 92.0 bits (227), Expect = 3e-17
Identities = 50/85 (58%), Positives = 61/85 (71%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
+G+KLGLGDFVFYSVLVGR AMYDL V++ +A++SGL TLILL V ALPALPISI
Sbjct: 146 KGVKLGLGDFVFYSVLVGRCAMYDLTIVFSGSVAVLSGLFGTLILLVVFNKALPALPISI 205
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNL 314
G L Y ++R + P + T NL
Sbjct: 206 FFGTLIYCVSRWAIVPLV--TTANL 228
[134][TOP]
>UniRef100_UPI0000E239A8 PREDICTED: presenilin 1 isoform 5 n=1 Tax=Pan troglodytes
RepID=UPI0000E239A8
Length = 445
Score = 91.7 bits (226), Expect = 4e-17
Identities = 46/80 (57%), Positives = 61/80 (76%), Gaps = 3/80 (3%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
G+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALPI
Sbjct: 356 GVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPI 415
Query: 394 SIALGVLFYFLTRLLMEPFI 335
SI G++FYF T L++PF+
Sbjct: 416 SITFGLVFYFATDYLVQPFM 435
[135][TOP]
>UniRef100_UPI0000D9BCD3 PREDICTED: presenilin 1 (Alzheimer disease 3) isoform 2 n=1
Tax=Macaca mulatta RepID=UPI0000D9BCD3
Length = 438
Score = 91.7 bits (226), Expect = 4e-17
Identities = 46/80 (57%), Positives = 61/80 (76%), Gaps = 3/80 (3%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
G+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALPI
Sbjct: 349 GVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPI 408
Query: 394 SIALGVLFYFLTRLLMEPFI 335
SI G++FYF T L++PF+
Sbjct: 409 SITFGLVFYFATDYLVQPFM 428
[136][TOP]
>UniRef100_UPI00006A3C99 PREDICTED: similar to presenilin 1 n=1 Tax=Ciona intestinalis
RepID=UPI00006A3C99
Length = 439
Score = 91.7 bits (226), Expect = 4e-17
Identities = 46/79 (58%), Positives = 61/79 (77%), Gaps = 1/79 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA-AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
+G+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TLILL++ R ALPALPIS
Sbjct: 351 KGVKLGLGDFIFYSVLVGKASATGDWNTTIACFVAILIGLCLTLILLAIYRKALPALPIS 410
Query: 391 IALGVLFYFLTRLLMEPFI 335
I G++FYF T ++ P++
Sbjct: 411 ITFGLVFYFSTDYVVRPYM 429
[137][TOP]
>UniRef100_Q54ET2 Presenilin-A n=1 Tax=Dictyostelium discoideum RepID=PSNA_DICDI
Length = 622
Score = 91.7 bits (226), Expect = 4e-17
Identities = 44/78 (56%), Positives = 61/78 (78%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
+ I+LGLGDFVFYSVL+G+AA Y + TV+ ++AII+GL TLILL+V R ALPALP+SI
Sbjct: 535 QSIRLGLGDFVFYSVLIGKAASYQITTVFTVFIAIITGLFLTLILLAVFRRALPALPMSI 594
Query: 388 ALGVLFYFLTRLLMEPFI 335
G++ +FLT ++ +I
Sbjct: 595 IFGIIVFFLTFKILIQYI 612
[138][TOP]
>UniRef100_UPI000056A67D Presenilin-1 (EC 3.4.23.-) (PS1) (Zf-PS1). n=1 Tax=Danio rerio
RepID=UPI000056A67D
Length = 456
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 366 RGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 425
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 426 ISITFGLVFYFATDNLVRPFM 446
[139][TOP]
>UniRef100_UPI00016E0E1A UPI00016E0E1A related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E0E1A
Length = 429
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 339 RGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 398
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 399 ISIFFGLVFYFATDNLVQPFM 419
[140][TOP]
>UniRef100_UPI00016E0E19 UPI00016E0E19 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E0E19
Length = 466
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 376 RGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 435
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 436 ISIFFGLVFYFATDNLVQPFM 456
[141][TOP]
>UniRef100_UPI00016E0E18 UPI00016E0E18 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E0E18
Length = 467
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 62/81 (76%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 437 ISIFFGLVFYFATDNLVQPFM 457
[142][TOP]
>UniRef100_UPI0000EB3684 Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5)
[Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF
subunit]. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3684
Length = 461
Score = 90.9 bits (224), Expect = 6e-17
Identities = 47/80 (58%), Positives = 60/80 (75%), Gaps = 3/80 (3%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALPI
Sbjct: 372 GVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPI 431
Query: 394 SIALGVLFYFLTRLLMEPFI 335
SI G++FYF T L+ PF+
Sbjct: 432 SITFGLIFYFSTDNLVRPFM 451
[143][TOP]
>UniRef100_O73869 PS1 protein (Fragment) n=1 Tax=Cyprinus carpio RepID=O73869_CYPCA
Length = 384
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 294 RGVKLGLGDFIFYSMLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 353
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 354 ISITFGLVFYFATDNLVRPFM 374
[144][TOP]
>UniRef100_B7P928 Seven trans-membrane protein, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7P928_IXOSC
Length = 358
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 63/81 (77%), Gaps = 4/81 (4%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
G+K+GLGDFVFYS+LVG+ A Y DL V AC++A++ G+ TL+LLS+ R ALPALP+S+
Sbjct: 272 GVKMGLGDFVFYSILVGKVATYGDLNVVAACFIAVLVGICVTLLLLSMLRVALPALPVSL 331
Query: 388 ALGVLFYFLTRLL---MEPFI 335
ALG+LF F L+ M+PF+
Sbjct: 332 ALGLLFAFPQELIHEFMQPFL 352
[145][TOP]
>UniRef100_Q9W6T7 Presenilin-1 n=1 Tax=Danio rerio RepID=PSN1_DANRE
Length = 456
Score = 90.9 bits (224), Expect = 6e-17
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 366 RGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 425
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L+ PF+
Sbjct: 426 ISITFGLVFYFATDNLVRPFM 446
[146][TOP]
>UniRef100_Q8HXW5 Presenilin-1 CTF12 n=1 Tax=Macaca fascicularis RepID=PSN1_MACFA
Length = 467
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 377 RGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALP 436
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FY T L++PF+
Sbjct: 437 ISITFGLVFYSATDYLVQPFM 457
[147][TOP]
>UniRef100_UPI00017B312F UPI00017B312F related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B312F
Length = 463
Score = 90.1 bits (222), Expect = 1e-16
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 373 RGVKLGLGDFIFYSMLVGNASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 432
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 433 ISIFFGLVFYFATDNLVQPFM 453
[148][TOP]
>UniRef100_Q4TA47 Chromosome 10 SCAF7449, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4TA47_TETNG
Length = 481
Score = 90.1 bits (222), Expect = 1e-16
Identities = 46/81 (56%), Positives = 61/81 (75%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRA---AMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYS+LVG A A D T AC++AI+ GL TL+LL++ + ALPALP
Sbjct: 391 RGVKLGLGDFIFYSMLVGNASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALP 450
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF T L++PF+
Sbjct: 451 ISIFFGLVFYFATDNLVQPFM 471
[149][TOP]
>UniRef100_Q4AEI4 Presenilin n=1 Tax=Ephydatia fluviatilis RepID=Q4AEI4_9METZ
Length = 476
Score = 89.7 bits (221), Expect = 1e-16
Identities = 44/81 (54%), Positives = 60/81 (74%), Gaps = 3/81 (3%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG KLGLGDF+FYS+LVGRAA D + + +C++AI+ GL T ++L + R ALPALP
Sbjct: 386 RGFKLGLGDFIFYSILVGRAAHDSDGDWVIISSCFVAILIGLCLTSLILGIVRRALPALP 445
Query: 397 ISIALGVLFYFLTRLLMEPFI 335
ISI G++FYF +R L+ PF+
Sbjct: 446 ISIFFGLMFYFSSRYLIAPFV 466
[150][TOP]
>UniRef100_B3S0V5 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3S0V5_TRIAD
Length = 325
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/77 (58%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISI 389
G+KLGLGDF+FYS+LVG+AA D T AC++AI+ GL TL+LL++ + ALPALPISI
Sbjct: 238 GVKLGLGDFIFYSILVGKAASNRDWNTTIACFVAILIGLCMTLLLLAIFKRALPALPISI 297
Query: 388 ALGVLFYFLTRLLMEPF 338
A G++F F T L+ PF
Sbjct: 298 AFGLIFNFATSGLIAPF 314
[151][TOP]
>UniRef100_Q54DE8 Presenilin-B n=1 Tax=Dictyostelium discoideum RepID=PSNB_DICDI
Length = 473
Score = 89.0 bits (219), Expect = 2e-16
Identities = 40/76 (52%), Positives = 60/76 (78%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIAL 383
+KLGLGDF+FYS+L+ RAA+ + V++ ++AI++GL TL+ L++ + ALPALPISI L
Sbjct: 388 LKLGLGDFIFYSLLISRAALVHMSCVFSTFIAILTGLFLTLLCLAIFKKALPALPISIFL 447
Query: 382 GVLFYFLTRLLMEPFI 335
G+LFY+L+ + PFI
Sbjct: 448 GILFYYLSNNFLTPFI 463
[152][TOP]
>UniRef100_UPI0001861953 hypothetical protein BRAFLDRAFT_114314 n=1 Tax=Branchiostoma
floridae RepID=UPI0001861953
Length = 417
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/78 (57%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 329 RGVKLGLGDFIFYSVLVGKASSNGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 388
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++F F T L+ PF
Sbjct: 389 ITFGLIFNFATANLVTPF 406
[153][TOP]
>UniRef100_Q8WS59 Presenilin n=1 Tax=Branchiostoma floridae RepID=Q8WS59_BRAFL
Length = 525
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/78 (57%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 437 RGVKLGLGDFIFYSVLVGKASSNGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 496
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++F F T L+ PF
Sbjct: 497 ITFGLIFNFATANLVTPF 514
[154][TOP]
>UniRef100_Q8WS58 Presenilin n=1 Tax=Branchiostoma floridae RepID=Q8WS58_BRAFL
Length = 504
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/78 (57%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 416 RGVKLGLGDFIFYSVLVGKASSNGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 475
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++F F T L+ PF
Sbjct: 476 ITFGLIFNFATANLVTPF 493
[155][TOP]
>UniRef100_C3Z2C5 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3Z2C5_BRAFL
Length = 506
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/78 (57%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVLVG+A+ D T AC++AI+ GL TL+LL++ + ALPALPIS
Sbjct: 418 RGVKLGLGDFIFYSVLVGKASSNGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPIS 477
Query: 391 IALGVLFYFLTRLLMEPF 338
I G++F F T L+ PF
Sbjct: 478 ITFGLIFNFATANLVTPF 495
[156][TOP]
>UniRef100_UPI0000E1F040 PREDICTED: presenilin 2 isoform 1 n=1 Tax=Pan troglodytes
RepID=UPI0000E1F040
Length = 442
Score = 87.4 bits (215), Expect = 7e-16
Identities = 47/80 (58%), Positives = 58/80 (72%), Gaps = 3/80 (3%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALPI 395
G+KLGLGDF+FYSVLVG+AA D T AC++AI+ GL TL+LL+V + ALPALPI
Sbjct: 360 GVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPI 419
Query: 394 SIALGVLFYFLTRLLMEPFI 335
SI G++FYF T L FI
Sbjct: 420 SITFGLIFYFSTDNLHSRFI 439
[157][TOP]
>UniRef100_A2F6H8 Clan AD, family A22, presenilin-like aspartic peptidase n=1
Tax=Trichomonas vaginalis G3 RepID=A2F6H8_TRIVA
Length = 418
Score = 82.8 bits (203), Expect = 2e-14
Identities = 39/87 (44%), Positives = 55/87 (63%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
GIKLGLGDFVFY +L+ RAA T C A++ GL TLI L++ LPALP S+
Sbjct: 332 GIKLGLGDFVFYGILISRAARKGWDTSVVCIEAVLLGLSITLIFLAILERPLPALPFSLV 391
Query: 385 LGVLFYFLTRLLMEPFIVGTATNLMMF 305
LG++FYF+ ++PF + L+++
Sbjct: 392 LGIIFYFIMPYTLKPFALNLRKLLLVY 418
[158][TOP]
>UniRef100_Q6AUZ8 Presenilin family protein, expressed n=1 Tax=Oryza sativa Japonica
Group RepID=Q6AUZ8_ORYSJ
Length = 474
Score = 82.4 bits (202), Expect = 2e-14
Identities = 39/45 (86%), Positives = 43/45 (95%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLS 428
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+
Sbjct: 374 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLA 418
[159][TOP]
>UniRef100_B9F9M2 Putative uncharacterized protein n=1 Tax=Oryza sativa Japonica
Group RepID=B9F9M2_ORYSJ
Length = 436
Score = 82.4 bits (202), Expect = 2e-14
Identities = 39/45 (86%), Positives = 43/45 (95%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLS 428
IKLGLGDF+FYSVLVGRAAMYD MTVYACYLAII+GLG TL+LL+
Sbjct: 374 IKLGLGDFIFYSVLVGRAAMYDYMTVYACYLAIIAGLGITLLLLA 418
[160][TOP]
>UniRef100_Q90X07 Presenilin-2 CTF subunit n=1 Tax=Gallus gallus RepID=PSN2_CHICK
Length = 451
Score = 82.0 bits (201), Expect = 3e-14
Identities = 44/73 (60%), Positives = 54/73 (73%), Gaps = 3/73 (4%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY---DLMTVYACYLAIISGLGCTLILLSVCRHALPALP 398
RG+KLGLGDF+FYSVLVG+AA D T A +AI+ GL TL+LL+V + ALPALP
Sbjct: 366 RGVKLGLGDFIFYSVLVGKAAATPSGDWNTTLAXXVAILIGLCLTLLLLAVFKKALPALP 425
Query: 397 ISIALGVLFYFLT 359
ISI G++FYF T
Sbjct: 426 ISITFGLIFYFST 438
[161][TOP]
>UniRef100_UPI000022181A Hypothetical protein CBG08092 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI000022181A
Length = 448
Score = 79.3 bits (194), Expect = 2e-13
Identities = 40/61 (65%), Positives = 50/61 (81%), Gaps = 1/61 (1%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPIS 392
RG+KLGLGDF+FYSVL+G+A+ Y D T ACY+AI+ GL TL+LL+V + ALPALPIS
Sbjct: 362 RGVKLGLGDFIFYSVLLGKASSYFDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPIS 421
Query: 391 I 389
I
Sbjct: 422 I 422
[162][TOP]
>UniRef100_B7QGI2 Presenilin, putative (Fragment) n=1 Tax=Ixodes scapularis
RepID=B7QGI2_IXOSC
Length = 392
Score = 78.2 bits (191), Expect = 4e-13
Identities = 37/81 (45%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMYDLMT-VYACYLAIISGLGCTLILLSVCRHALPALPISI 389
G+K+GLGDF+FYS+LVG+A+ + ++ V CY+ ++ G+ TL LL + + +PALP+SI
Sbjct: 307 GMKMGLGDFIFYSILVGKASRHGTVSAVVICYIYVVIGIILTLALLVIAQKPVPALPLSI 366
Query: 388 ALGVLFYFLTRLLMEPFIVGT 326
+LG+ YF T +EPF+ T
Sbjct: 367 SLGMFAYFSTISFVEPFMEET 387
[163][TOP]
>UniRef100_A2DZ73 Clan AD, family A22, presenilin-like aspartic peptidase n=1
Tax=Trichomonas vaginalis G3 RepID=A2DZ73_TRIVA
Length = 391
Score = 75.9 bits (185), Expect = 2e-12
Identities = 39/87 (44%), Positives = 50/87 (57%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
GIKLGLGDFVFY +LV RAA C A+I GL TL+ L+V LPALP S+A
Sbjct: 305 GIKLGLGDFVFYGILVSRAARIGWDITILCIFAVILGLSLTLVCLAVWERPLPALPFSLA 364
Query: 385 LGVLFYFLTRLLMEPFIVGTATNLMMF 305
LG++F+ + + F L+ F
Sbjct: 365 LGIVFFIIGAMTFRQFCEHMRWGLVAF 391
[164][TOP]
>UniRef100_A8XEJ8 C. briggsae CBR-HOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XEJ8_CAEBR
Length = 358
Score = 73.9 bits (180), Expect = 8e-12
Identities = 38/87 (43%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYD-LMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
I+LG+GDFVFYS+++G AA L TV AC+L+ + GL TL ++S+ + ALPALP +
Sbjct: 272 IRLGMGDFVFYSLMLGNAAQTSPLTTVLACFLSNLVGLTITLPVVSLSQTALPALPFPLL 331
Query: 385 LGVLFYFLTRLLMEPFIVGTATNLMMF 305
+ LFYF + + + PF + L++F
Sbjct: 332 IAALFYFSSHVALTPFTNLCSLTLILF 358
[165][TOP]
>UniRef100_Q38F54 Presenilin-like aspartic peptidase, putative n=1 Tax=Trypanosoma
brucei RepID=Q38F54_9TRYP
Length = 365
Score = 70.1 bits (170), Expect = 1e-10
Identities = 39/76 (51%), Positives = 51/76 (67%), Gaps = 3/76 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYS+L G AA Y + +A++ GL TL+ L + + ALPALPISI
Sbjct: 278 KLGLGDFIFYSLLCGIAASYSFIPWLMSVIAVLFGLVGTLLFLVLFKEKLTALPALPISI 337
Query: 388 ALGVLFYFLTRLLMEP 341
ALGV+ YF +R L+ P
Sbjct: 338 ALGVITYFSSRYLVVP 353
[166][TOP]
>UniRef100_C9ZXP4 Presenilin-like aspartic peptidase, putative (Presenilin-like
aspartic peptidase, clan ad, family a22a, putative) n=1
Tax=Trypanosoma brucei gambiense DAL972
RepID=C9ZXP4_TRYBG
Length = 365
Score = 70.1 bits (170), Expect = 1e-10
Identities = 39/76 (51%), Positives = 51/76 (67%), Gaps = 3/76 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYS+L G AA Y + +A++ GL TL+ L + + ALPALPISI
Sbjct: 278 KLGLGDFIFYSLLCGIAASYSFIPWLMSVIAVLFGLVGTLLFLVLFKEKLTALPALPISI 337
Query: 388 ALGVLFYFLTRLLMEP 341
ALGV+ YF +R L+ P
Sbjct: 338 ALGVITYFSSRYLVVP 353
[167][TOP]
>UniRef100_A2G9L8 Clan AD, family A22, presenilin-like aspartic peptidase n=1
Tax=Trichomonas vaginalis G3 RepID=A2G9L8_TRIVA
Length = 439
Score = 70.1 bits (170), Expect = 1e-10
Identities = 36/87 (41%), Positives = 49/87 (56%)
Frame = -2
Query: 565 GIKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
G+KLGLGDF+FY +LV RAA LA++ GL TLI L+ LPALP S+A
Sbjct: 353 GVKLGLGDFIFYGILVTRAARVGWDIAILDILAVMDGLALTLICLAYFERPLPALPFSLA 412
Query: 385 LGVLFYFLTRLLMEPFIVGTATNLMMF 305
LG++FY + F +++F
Sbjct: 413 LGIIFYLIGAYTFRGFSTNLRKLVLVF 439
[168][TOP]
>UniRef100_Q4CMV5 Presenilin-like aspartic peptidase, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4CMV5_TRYCR
Length = 372
Score = 68.9 bits (167), Expect = 2e-10
Identities = 39/76 (51%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYSVL RAA+Y M A +A+ GL TL +L + + ALPALPISI
Sbjct: 285 KLGLGDFIFYSVLSARAALYAFMPWAASTVAVCFGLVATLTMLLMYKSRFPALPALPISI 344
Query: 388 ALGVLFYFLTRLLMEP 341
GV +FL R ++ P
Sbjct: 345 CFGVAVFFLYRFVVTP 360
[169][TOP]
>UniRef100_O02100 Presenilin hop-1 n=1 Tax=Caenorhabditis elegans RepID=HOP1_CAEEL
Length = 358
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/76 (42%), Positives = 52/76 (68%), Gaps = 1/76 (1%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
I+LG+GDFVFYS+++G L TV AC+++ + GL TL ++++ + ALPALP +A
Sbjct: 272 IRLGMGDFVFYSLMLGNTVQTCPLPTVVACFVSNLVGLTITLPIVTLSQTALPALPFPLA 331
Query: 385 LGVLFYFLTRLLMEPF 338
+ +FYF + + + PF
Sbjct: 332 IAAIFYFSSHIALTPF 347
[170][TOP]
>UniRef100_Q4E0Z2 Presenilin-like aspartic peptidase, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4E0Z2_TRYCR
Length = 372
Score = 67.8 bits (164), Expect = 6e-10
Identities = 39/76 (51%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYSVL RAA+Y M A +A+ GL TL L + + ALPALPISI
Sbjct: 285 KLGLGDFIFYSVLSARAALYAFMPWAASTVAVCFGLVATLTTLLMYKSRFPALPALPISI 344
Query: 388 ALGVLFYFLTRLLMEP 341
GV +FL R ++ P
Sbjct: 345 CFGVAVFFLYRFVVTP 360
[171][TOP]
>UniRef100_A4HWP2 Presenilin-like aspartic peptidase, putative (Presenilin-like
aspartic peptidase, clan ad,family a22a, putative) n=1
Tax=Leishmania infantum RepID=A4HWP2_LEIIN
Length = 352
Score = 65.9 bits (159), Expect = 2e-09
Identities = 37/87 (42%), Positives = 58/87 (66%), Gaps = 3/87 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYS+LVGRA+ ++ C ++I++G+ TL+ L + R+ ALPALP SI
Sbjct: 265 KLGLGDFIFYSLLVGRASFSGFVSWSFCMVSILAGMLGTLLSLLLFRNSLRALPALPCSI 324
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMM 308
L + + L RL++E T+ +L++
Sbjct: 325 FLSTVVFVLCRLIVESLSSFTSHHLLV 351
[172][TOP]
>UniRef100_Q4QF26 Presenilin-like aspartic peptidase, putative (Presenilin-like
aspartic peptidase, clan ad, family a22a, putative) n=1
Tax=Leishmania major RepID=Q4QF26_LEIMA
Length = 352
Score = 65.5 bits (158), Expect = 3e-09
Identities = 37/87 (42%), Positives = 58/87 (66%), Gaps = 3/87 (3%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYS+LVGRA+ ++ C ++I++G+ TL+ L + R+ ALPALP SI
Sbjct: 265 KLGLGDFIFYSLLVGRASFSGFVSWGFCMVSILAGMLGTLLSLLLFRNSLRALPALPCSI 324
Query: 388 ALGVLFYFLTRLLMEPFIVGTATNLMM 308
L + + L RL++E T+ +L++
Sbjct: 325 FLSTVVFVLCRLIVESLSSFTSHHLLV 351
[173][TOP]
>UniRef100_A8PM37 Presenilin spe-4, putative n=1 Tax=Brugia malayi RepID=A8PM37_BRUMA
Length = 187
Score = 63.5 bits (153), Expect = 1e-08
Identities = 35/76 (46%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
++LG+GDFVFYS+LVG+AA M V + I+ GL TL +LS PALP+SI
Sbjct: 98 VRLGMGDFVFYSLLVGKAAATRSTMCVAGSVVGILVGLVITLTVLSSDDETTPALPVSIT 157
Query: 385 LGVLFYFLTRLLMEPF 338
+ +L +F L +EPF
Sbjct: 158 IALLLHFGIYLFVEPF 173
[174][TOP]
>UniRef100_A4H8C1 Presenilin-like aspartic peptidase, putative (Presenilin-like
aspartic peptidase, clan ad,family a22a, putative) n=1
Tax=Leishmania braziliensis RepID=A4H8C1_LEIBR
Length = 352
Score = 61.6 bits (148), Expect = 4e-08
Identities = 34/74 (45%), Positives = 51/74 (68%), Gaps = 3/74 (4%)
Frame = -2
Query: 559 KLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIISGLGCTLILLSVCRH---ALPALPISI 389
KLGLGDF+FYS+LV RA++ ++ C ++I+ G+ TL+ L + R+ ALPALP SI
Sbjct: 265 KLGLGDFIFYSLLVSRASLSGFVSWGFCVVSILVGMVGTLLSLLLFRNSLRALPALPCSI 324
Query: 388 ALGVLFYFLTRLLM 347
L ++ + L RLL+
Sbjct: 325 FLSIVVFVLCRLLV 338
[175][TOP]
>UniRef100_UPI0001925A79 PREDICTED: similar to presenilin 1, partial n=1 Tax=Hydra
magnipapillata RepID=UPI0001925A79
Length = 287
Score = 56.2 bits (134), Expect = 2e-06
Identities = 30/48 (62%), Positives = 37/48 (77%), Gaps = 3/48 (6%)
Frame = -2
Query: 568 RGIKLGLGDFVFYSVLVGRAAMY-DLMTVYACYLA--IISGLGCTLIL 434
RG+KLGLGDF+FYSVLVG+A+ Y D T AC++A I+SGL TL L
Sbjct: 196 RGVKLGLGDFIFYSVLVGKASSYKDWNTTLACFVAILIVSGLFLTLFL 243
[176][TOP]
>UniRef100_A8XEM9 C. briggsae CBR-SPE-4 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XEM9_CAEBR
Length = 483
Score = 55.5 bits (132), Expect = 3e-06
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%)
Frame = -2
Query: 562 IKLGLGDFVFYSVLVGRAAMYDL-MTVYACYLAIISGLGCTLILLSVCRHALPALPISIA 386
++LG GDFVFYS+L+G+AA ++V I+ GL TL +LS PALP+ +
Sbjct: 403 VRLGFGDFVFYSLLIGQAATGGCPISVGFAAFGILFGLIATLTVLSSEESTTPALPLPVI 462
Query: 385 LGVLFYFLTRLLME 344
G YF++R L++
Sbjct: 463 CGTFCYFVSRFLVD 476
[177][TOP]
>UniRef100_A6MKL6 Presenilin 2-like protein (Fragment) n=1 Tax=Callithrix jacchus
RepID=A6MKL6_CALJA
Length = 57
Score = 53.9 bits (128), Expect = 8e-06
Identities = 26/47 (55%), Positives = 36/47 (76%)
Frame = -2
Query: 475 YLAIISGLGCTLILLSVCRHALPALPISIALGVLFYFLTRLLMEPFI 335
++AI+ GL TL+LL+V + ALPALPISI G++FYF T L+ PF+
Sbjct: 1 FVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFM 47