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[1][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 312 bits (800), Expect = 7e-84
Identities = 150/167 (89%), Positives = 160/167 (95%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD IG+DG A E YQKDLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 160 FGITVAGYPEAHPDAIGSDGFATPEDYQKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFV 219
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIH
Sbjct: 220 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIH 279
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+AHGIKT+HLYTLNMEKSALAILM+LGLIEESKI+R+L
Sbjct: 280 LGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKITRAL 326
[2][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 310 bits (794), Expect = 3e-83
Identities = 150/162 (92%), Positives = 158/162 (97%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI +DGLA +EGYQ DLAYLKSKVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 147 FGITVAGYPEAHPDVIESDGLATSEGYQNDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 206
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPA+IMAALEPIKDNEEAVKAYGIH
Sbjct: 207 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPADIMAALEPIKDNEEAVKAYGIH 266
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
LGTEMCKKI+AHGI T+HLYTLNMEKSALAILM+LGLIEE+K
Sbjct: 267 LGTEMCKKILAHGINTLHLYTLNMEKSALAILMNLGLIEETK 308
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 308 bits (789), Expect = 1e-82
Identities = 149/167 (89%), Positives = 157/167 (94%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVIG+DG A E Y KDLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 157 FGITVAGYPEAHPDVIGSDGFATLEDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFV 216
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPINNYKGFIRM GFCKTKIPAE+ AALEPIKDNEEAV+AYGIH
Sbjct: 217 NDCRQIGINCPIVPGIMPINNYKGFIRMAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIH 276
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+AHGIKT+HLYTLNMEKSALAILM+LGLIEESKI+R L
Sbjct: 277 LGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKITRPL 323
[4][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 307 bits (787), Expect = 2e-82
Identities = 148/167 (88%), Positives = 158/167 (94%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD+I +DGLA E YQ+DL YLK KVDAGADLI+TQLFYDTDIFLKFV
Sbjct: 161 FGITVAGYPEAHPDMIESDGLATPENYQRDLEYLKRKVDAGADLIITQLFYDTDIFLKFV 220
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPINNYKGF+RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIH
Sbjct: 221 NDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIH 280
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKIMAHGIKT+HLYTLNMEKSALAILM+LGLIEESKISR L
Sbjct: 281 LGTEMCKKIMAHGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPL 327
[5][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 305 bits (782), Expect = 8e-82
Identities = 144/167 (86%), Positives = 159/167 (95%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVIG +GLA E YQ DL YLK K+DAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLKKKIDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI+CPIVPGIMPINNY+GF+RMTGFCKTKIP E+MAALEPIKDNEEAVKAYGIH
Sbjct: 206 NDCRQIGISCPIVPGIMPINNYRGFLRMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKK++AHG+K++HLYTLNMEKSALAILM+LG+I+ESKISRSL
Sbjct: 266 LGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNLGMIDESKISRSL 312
[6][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 303 bits (777), Expect = 3e-81
Identities = 149/165 (90%), Positives = 158/165 (95%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI N G+A +E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 147 FGITVAGYPEAHPDVILN-GVATSEAYQSDLAYLKRKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISR 496
LGTEMCKKI+AHGIKTVHLYTLNMEKSALAILM+LGLIEESKISR
Sbjct: 266 LGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKISR 310
[7][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 303 bits (777), Expect = 3e-81
Identities = 149/165 (90%), Positives = 158/165 (95%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI N G+A +E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 147 FGITVAGYPEAHPDVILN-GVATSEAYQSDLAYLKRKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISR 496
LGTEMCKKI+AHGIKTVHLYTLNMEKSALAILM+LGLIEESKISR
Sbjct: 266 LGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKISR 310
[8][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 296 bits (759), Expect = 4e-79
Identities = 146/167 (87%), Positives = 153/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD I + A E Y DLAYLK KVDAGADLI+TQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLKQKVDAGADLIITQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+A GIKT+HLYTLNMEKSAL ILM+LGLIEESKISRSL
Sbjct: 266 LGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLGLIEESKISRSL 312
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 296 bits (759), Expect = 4e-79
Identities = 146/167 (87%), Positives = 153/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD I + A E Y DLAYLK KVDAGADLI+TQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLKQKVDAGADLIITQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+A GIKT+HLYTLNMEKSAL ILM+LGLIEESKISRSL
Sbjct: 266 LGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLGLIEESKISRSL 312
[10][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 296 bits (757), Expect = 7e-79
Identities = 144/167 (86%), Positives = 157/167 (94%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHP+VI + A E Y+KDLAYLK KVDAGAD+IVTQLFYDTDIFLKFV
Sbjct: 134 FGITVAGYPEAHPEVILGEEGATEEAYRKDLAYLKRKVDAGADVIVTQLFYDTDIFLKFV 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIPAEI AAL+PIKDNEEAVKAYGIH
Sbjct: 194 NDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEAVKAYGIH 253
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+A GIKT+HLYTLNMEK+ALAILM+LGLIEESK+SR+L
Sbjct: 254 LGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTL 300
[11][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 292 bits (747), Expect = 1e-77
Identities = 140/167 (83%), Positives = 153/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI DGLA E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDVIEADGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
TEMCKKI+AHGI ++HLYTLN++KSA+ ILM+LGLI+ESKISRSL
Sbjct: 266 FATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSL 312
[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 292 bits (747), Expect = 1e-77
Identities = 141/167 (84%), Positives = 152/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD I +G A E Y DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIP+EI AAL+PIKDNEEAVK YGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVKQYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+A GIKT+HLYTLNM+KSA+ ILM+LGLIEESK+SR L
Sbjct: 266 LGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPL 312
[13][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 292 bits (747), Expect = 1e-77
Identities = 140/167 (83%), Positives = 153/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI DGLA E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDVIEADGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
TEMCKKI+AHGI ++HLYTLN++KSA+ ILM+LGLI+ESKISRSL
Sbjct: 266 FATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSL 312
[14][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 292 bits (747), Expect = 1e-77
Identities = 140/167 (83%), Positives = 153/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI DGLA E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDVIEADGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
TEMCKKI+AHGI ++HLYTLN++KSA+ ILM+LGLI+ESKISRSL
Sbjct: 266 FATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSL 312
[15][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 291 bits (744), Expect = 2e-77
Identities = 140/167 (83%), Positives = 152/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD I +G A E Y DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIP+EI AAL+PIKDNEEAV+ YGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+A GIKT+HLYTLNM+KSA+ ILM+LGLIEESK+SR L
Sbjct: 266 LGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPL 312
[16][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 288 bits (737), Expect = 1e-76
Identities = 140/167 (83%), Positives = 152/167 (91%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPD+I N+ A E YQKDLAYLK KVDAGADLI+TQLFYDTDI+LKFV
Sbjct: 146 FGITVAGYPEAHPDMIKNEVGATEEDYQKDLAYLKLKVDAGADLIITQLFYDTDIYLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI CPIVPGIMPINNYKGFIRM GFCKTKIP+EI AALEPIKDNEEAV+AYGIH
Sbjct: 206 NDCRQIGIKCPIVPGIMPINNYKGFIRMAGFCKTKIPSEITAALEPIKDNEEAVRAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+AHGIKT+HLYTLNMEKSAL IL +LGLI+ +KI R L
Sbjct: 266 LGTEMCKKILAHGIKTLHLYTLNMEKSALGILANLGLIDMTKIRRPL 312
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 276 bits (707), Expect = 4e-73
Identities = 130/167 (77%), Positives = 149/167 (89%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHP+VIG DG+A E YQKDLAYLK K DAG ++I+TQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPEVIGEDGVASEEAYQKDLAYLKEKCDAGGEVIITQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI PIVPGIMPI NYKGF+RMT CKTK+PAEIMAALEPIKDN+EAV+AYGIH
Sbjct: 206 NDCRQIGIKVPIVPGIMPIQNYKGFLRMTTLCKTKVPAEIMAALEPIKDNDEAVRAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+AH I+T+HLY+LN+EKS L IL +LGLI+ S++SR L
Sbjct: 266 LGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLGLIDFSRVSRPL 312
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 276 bits (707), Expect = 4e-73
Identities = 129/167 (77%), Positives = 148/167 (88%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVIG DG+A E Y+KDLAYLK K DAG ++IVTQLFYDTDIFLKFV
Sbjct: 146 FGITVAGYPEAHPDVIGEDGIASEEAYKKDLAYLKEKCDAGGEVIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGI P+VPGIMPI NYKGF+RMT CKTK+PAEIMA LEPIKDN+EAV+AYGIH
Sbjct: 206 NDCRQIGIKAPVVPGIMPIQNYKGFLRMTSLCKTKVPAEIMATLEPIKDNDEAVRAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LGTEMCKKI+AH I+T+HLY+LN+EKS L IL +LGLI+ SK++R L
Sbjct: 266 LGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLGLIDFSKVTRPL 312
[19][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 264 bits (674), Expect = 3e-69
Identities = 134/165 (81%), Positives = 146/165 (88%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGIT+AGYPEAHPDVI N G+A +E YQ DLAYLK KVDAGADLIVTQLFYDTDIFLKFV
Sbjct: 147 FGITVAGYPEAHPDVILN-GVATSEAYQSDLAYLKRKVDAGADLIVTQLFYDTDIFLKFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCRQIGITCPIVPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIH
Sbjct: 206 NDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIH 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISR 496
LGTEMCKKI+AHGIKT L T+++ +LGLIEESKISR
Sbjct: 266 LGTEMCKKILAHGIKTFGL-TMDLP------WQNLGLIEESKISR 303
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 229 bits (583), Expect = 1e-58
Identities = 110/168 (65%), Positives = 133/168 (79%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AGYPEAHPD I +D + Y D+AYLK KVDAG D+IVTQLFYD D+FL+FV
Sbjct: 140 FGICVAGYPEAHPDGIVDDPEQMKKNYWADIAYLKQKVDAGGDMIVTQLFYDVDVFLQFV 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR +GITCPI+PGIMPI Y GF RMTGFCKTK+PAEI ALE IKDN+EAVKAYGI
Sbjct: 200 KDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGID 259
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
LG MC++++A G + VH+YTLN+EKSA+AIL LGL++ S++ R L
Sbjct: 260 LGVRMCRQLLASGEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPL 307
[21][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 219 bits (557), Expect = 1e-55
Identities = 103/122 (84%), Positives = 115/122 (94%)
Frame = +2
Query: 137 VTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALE 316
VTQLFYDTDIFLKFVNDCRQIGI CPIVPGIMPI+NYKGF+RM GFCKTKIPAE+ AALE
Sbjct: 1 VTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALE 60
Query: 317 PIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISR 496
PIKDN+EAVKAYGIH TEMCKKI+AHGI ++HLYTLN++KSA+ ILM+LGLI+ESKISR
Sbjct: 61 PIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISR 120
Query: 497 SL 502
SL
Sbjct: 121 SL 122
[22][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 180 bits (457), Expect = 4e-44
Identities = 85/164 (51%), Positives = 111/164 (67%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++AGYPE H D + + +D+ YLK KVDAGAD I+TQLFYD DIF +FV
Sbjct: 148 FCISVAGYPEGHSDCVSKE---------EDIRYLKEKVDAGADFIITQLFYDCDIFCEFV 198
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR +GI CPI+PGIMPI Y GF+RMT KTK+P IM LEPIKDN+E VK YG+
Sbjct: 199 EKCRSVGINCPIIPGIMPIQTYAGFVRMTTLSKTKVPQYIMDNLEPIKDNDEEVKKYGVR 258
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKIS 493
L EM K+++ G++ +H YTLN+E+S +L L L+ ++S
Sbjct: 259 LCVEMSKRLLDFGVEGLHFYTLNLERSVRKVLKGLQLVTPDQLS 302
[23][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 175 bits (443), Expect = 2e-42
Identities = 82/168 (48%), Positives = 114/168 (67%), Gaps = 4/168 (2%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI++AGYPE HP+ I E Y+K++ YLK KVDAG D I+TQ+F+D ++F FV
Sbjct: 159 FGISVAGYPEGHPNRISQLSEEEDEDYKKEMDYLKEKVDAGGDFIITQMFFDAEVFKTFV 218
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCR GITCP+VPG+M IN Y GF +MT FCKT++P + ++ IKD+ +AVK +G+
Sbjct: 219 NDCRTWGITCPVVPGLMCINAYPGFKKMTKFCKTRVPKSLEERMDAIKDDADAVKKFGVE 278
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL----GLIEESKIS 493
G E+ + ++ G+K +H YTLN+EK I L GLIE+S+ S
Sbjct: 279 FGAEISRNLLDSGVKILHFYTLNLEKVVYGITDELGITSGLIEKSEES 326
[24][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 162 bits (411), Expect = 9e-39
Identities = 81/178 (45%), Positives = 110/178 (61%), Gaps = 22/178 (12%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDG----LAPAEG-----------------YQKDLAYLKSKVD 118
F + +AGYPE HP+ I L AE Y K++ YLK KVD
Sbjct: 199 FHLAVAGYPEGHPNAISEIADPTTLTAAEAARASVTDGKTYCCLDADYHKEMEYLKKKVD 258
Query: 119 AGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAE 298
AG D+I+TQ+F+D +FL+FV DCR GIT PIVPG+M IN Y GF++M FCKT++P
Sbjct: 259 AGGDMIMTQMFFDAAVFLQFVEDCRAWGITVPIVPGLMCINAYAGFVKMAKFCKTRVPET 318
Query: 299 IMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLG 469
+ A +E IKD+ AVKA+G+ G EMC+ ++A G + +H YTLN+EK +L +LG
Sbjct: 319 LRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEKVVYGVLDALG 376
[25][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 162 bits (410), Expect = 1e-38
Identities = 73/162 (45%), Positives = 105/162 (64%), Gaps = 2/162 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F +++AGYPE HP I DG E +QK+L YLK KVDAGA +++TQLFYD +++KFV
Sbjct: 148 FCVSVAGYPEGHPSRIAEDGTILDEDHQKELEYLKEKVDAGASVVITQLFYDASLYVKFV 207
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR++GIT PI+ G++PI Y GF RM CKT++P ++ +E +K+N EA+K YG+
Sbjct: 208 KDCREMGITVPIIAGLLPITTYAGFTRMVSLCKTRVPGDVKKRVEELKENPEALKEYGVE 267
Query: 362 LGTEMCKKIMAHGI--KTVHLYTLNMEKSALAILMSLGLIEE 481
+M ++I A G+ +H YTLN +L L + E
Sbjct: 268 QCVQMIERIRASGLDYHHLHFYTLNSSAQTFQVLKRLNALVE 309
[26][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 162 bits (409), Expect = 1e-38
Identities = 78/161 (48%), Positives = 106/161 (65%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AE YQ+DL +LK KVDAGAD ++TQLF+ + FLKF+
Sbjct: 194 FDICVAGYPTGHPE---------AESYQQDLRHLKEKVDAGADFVITQLFFRAETFLKFL 244
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+DCR IGITCPI+PGI PI Y+ ++ K ++P EI + LEPIKDN+ A++ YGI
Sbjct: 245 DDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQ 304
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L EMC+ ++ G + +H YTLN E + + +L LGL E
Sbjct: 305 LAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTE 345
[27][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 161 bits (407), Expect = 3e-38
Identities = 77/161 (47%), Positives = 105/161 (65%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AEGY +DL +LK KVDAGAD I+TQLF+ + FL F+
Sbjct: 184 FDICVAGYPRGHPE---------AEGYDQDLKHLKEKVDAGADFIITQLFFRAETFLTFI 234
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCR IGITCPI+PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI
Sbjct: 235 NDCRAIGITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGID 294
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G + +H YTLN E + + +L LG+ +E
Sbjct: 295 LAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[28][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 161 bits (407), Expect = 3e-38
Identities = 77/161 (47%), Positives = 105/161 (65%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AEGY +DL +LK KVDAGAD I+TQLF+ + FL F+
Sbjct: 184 FDICVAGYPRGHPE---------AEGYDQDLKHLKEKVDAGADFIITQLFFRAETFLTFI 234
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCR IGITCPI+PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI
Sbjct: 235 NDCRAIGITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGID 294
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G + +H YTLN E + + +L LG+ +E
Sbjct: 295 LAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[29][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 158 bits (400), Expect = 2e-37
Identities = 79/161 (49%), Positives = 101/161 (62%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AE Y+ DL +LK KVDAGA IVTQLF+ + FLKFV
Sbjct: 190 FDICVAGYPTGHPE---------AESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFV 240
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR IGITCPI+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 241 KDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQ 300
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
EMCK ++A G + +H YTLN E + + +L LGL E
Sbjct: 301 QAVEMCKVLLASGEVSGLHFYTLNREVATMEVLRQLGLWAE 341
[30][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 158 bits (399), Expect = 2e-37
Identities = 74/158 (46%), Positives = 102/158 (64%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD + YQ DL +LK K+DAG I+TQLF+ + FL FV
Sbjct: 162 FSICVAGYPNGHPD---------STSYQDDLLHLKEKIDAGGQFIITQLFFTAEEFLTFV 212
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGI CPI+PGI PI + +++T K IP EI +EPIKDN+ A++ YGI
Sbjct: 213 KDCREIGIDCPIIPGIFPIQTNRSLVQLTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGID 272
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
L T+MC+ ++ G + +H+YTLN+E + + IL +LGL
Sbjct: 273 LATDMCRTLLNSGKVHGLHMYTLNLETATIQILKNLGL 310
[31][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 157 bits (398), Expect = 3e-37
Identities = 72/158 (45%), Positives = 105/158 (66%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AE Y++DL +LK KVDAGAD ++TQLF+ + FLKF+
Sbjct: 194 FDICVAGYPTGHPE---------AESYEQDLRHLKEKVDAGADFVITQLFFRAETFLKFL 244
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR++GITCP++PGI PI Y+ ++ K ++P EI + +EPIKDN+ A++ YGI
Sbjct: 245 EDCRRVGITCPVLPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQ 304
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
L +MC+ ++ G + +H YTLN E + + +L LGL
Sbjct: 305 LAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGL 342
[32][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 157 bits (398), Expect = 3e-37
Identities = 72/158 (45%), Positives = 105/158 (66%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HP+ AE Y++DL +LK KVDAGAD ++TQLF+ + FLKF+
Sbjct: 194 FDICVAGYPTGHPE---------AESYEQDLRHLKEKVDAGADFVITQLFFRAETFLKFL 244
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR++GITCP++PGI PI Y+ ++ K ++P EI + +EPIKDN+ A++ YGI
Sbjct: 245 EDCRRVGITCPVLPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQ 304
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
L +MC+ ++ G + +H YTLN E + + +L LGL
Sbjct: 305 LAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGL 342
[33][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 157 bits (396), Expect = 5e-37
Identities = 74/161 (45%), Positives = 104/161 (64%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD AE Y +DL +LK K+DAGAD I+TQLF+ ++ FL F+
Sbjct: 184 FDICVAGYPRGHPD---------AESYDQDLKHLKEKIDAGADFIITQLFFRSETFLTFL 234
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR IGITCP++PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI
Sbjct: 235 KDCRAIGITCPVLPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGID 294
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G + +H YTLN E + + +L LG+ +E
Sbjct: 295 LAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[34][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 154 bits (390), Expect = 2e-36
Identities = 79/173 (45%), Positives = 109/173 (63%), Gaps = 6/173 (3%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE H + AE ++DL +LK KVDAGADLI+TQLFYDT++F KFV
Sbjct: 120 FCIAVAGYPEGHLE---------AESIEEDLVHLKEKVDAGADLIITQLFYDTEVFFKFV 170
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++GI PI PGIMPI +Y GF +MT FCKTK+P I LE +K +++ VK G+
Sbjct: 171 AAVRKLGIQVPIFPGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVE 230
Query: 362 LGTEMCKKIMAHGIK------TVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
+ MC +IM++G+ +H YTLN+E S I+ L +++ +R L
Sbjct: 231 ICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVL 283
[35][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 154 bits (390), Expect = 2e-36
Identities = 79/173 (45%), Positives = 109/173 (63%), Gaps = 6/173 (3%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE H + AE ++DL +LK KVDAGADLI+TQLFYDT++F KFV
Sbjct: 120 FCIAVAGYPEGHLE---------AESIEEDLVHLKEKVDAGADLIITQLFYDTEVFFKFV 170
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++GI PI PGIMPI +Y GF +MT FCKTK+P I LE +K +++ VK G+
Sbjct: 171 AAVRKLGIRVPIFPGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVE 230
Query: 362 LGTEMCKKIMAHGIK------TVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
+ MC +IM++G+ +H YTLN+E S I+ L +++ +R L
Sbjct: 231 ICVAMCSQIMSYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVL 283
[36][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 154 bits (389), Expect = 3e-36
Identities = 71/162 (43%), Positives = 102/162 (62%), Gaps = 2/162 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F +++AGYPE HP I +G E +QK+L YLK KVDAGA I+TQLFYD +++KFV
Sbjct: 148 FCVSVAGYPEGHPSRIAENGTISHEDHQKELEYLKEKVDAGASFIITQLFYDASLYVKFV 207
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR++GIT PI+ G++PI Y GF+RM CKT +P+++ +E +K+N + +K YG+
Sbjct: 208 KRCREVGITVPILAGLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVE 267
Query: 362 LGTEMCKKIMAHGI--KTVHLYTLNMEKSALAILMSLGLIEE 481
+M + I A G+ +H YTLN IL L + E
Sbjct: 268 QCVQMIECIRASGLDYHHLHFYTLNNSAQIFKILKRLNALVE 309
[37][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 153 bits (387), Expect = 5e-36
Identities = 70/162 (43%), Positives = 101/162 (62%), Gaps = 2/162 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F +++AGYPE HP I DG E +QK+L YLK KVDAGA I+TQLFYD ++++FV
Sbjct: 148 FCVSVAGYPEGHPSRIAEDGAISDEDHQKELEYLKEKVDAGASFIITQLFYDASLYVQFV 207
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR+IGIT PI+ G++PI Y GF+RM CKT +P+++ +E +K+N + +K YG+
Sbjct: 208 KRCREIGITVPILAGLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVE 267
Query: 362 LGTEMCKKIMAHGI--KTVHLYTLNMEKSALAILMSLGLIEE 481
+M + I G+ +H YTLN +L L + E
Sbjct: 268 QCVQMIECIRTSGLDYHHLHFYTLNNSAQTFKVLKRLNALVE 309
[38][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 153 bits (387), Expect = 5e-36
Identities = 80/157 (50%), Positives = 100/157 (63%), Gaps = 1/157 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE H D + D +DL YLK K DAGA I+TQLFYD D FL++
Sbjct: 207 FCIGVAGYPEGHADYVDRD-------VNRDLRYLKDKQDAGAQYIITQLFYDVDRFLEWY 259
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGIMPI NY F RMT CK ++P I+ ALEPIK ++ AVK YG+
Sbjct: 260 RDCREIGITIPILPGIMPIQNYSSFRRMTNLCKVQVPQLILDALEPIKSDDAAVKEYGVS 319
Query: 362 LGTEMCKKI-MAHGIKTVHLYTLNMEKSALAILMSLG 469
L M +I + ++ HL +LN+EKS IL LG
Sbjct: 320 LSIHMVGRIFLETDVRGFHLCSLNLEKSIERILEGLG 356
[39][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 152 bits (385), Expect = 9e-36
Identities = 78/158 (49%), Positives = 100/158 (63%), Gaps = 3/158 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AG+PE HP + + +L +LK K+ AGAD I++Q YDT+ FL F
Sbjct: 172 FGIAVAGHPEGHPS---------STSPEDELDHLKEKMRAGADFIISQFVYDTERFLDFC 222
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR +GI CPI+PGIMPI +Y F RMT +C +P EI LEPIKD++EAVK G
Sbjct: 223 YRCRDVGIQCPILPGIMPIQSYSSFTRMTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCS 282
Query: 362 LGTEMCKKIMAHGIKT---VHLYTLNMEKSALAILMSL 466
L EMC++I+A I VH YTLN+E+SA ILM L
Sbjct: 283 LAAEMCRQILADPIAKIDGVHFYTLNLERSATRILMQL 320
[40][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 150 bits (378), Expect = 6e-35
Identities = 72/161 (44%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ A +++D+ YLK KV AGAD I+TQLF+ D F FV
Sbjct: 184 FDICVAGYPKGHPE---------ATSFEEDVQYLKEKVSAGADFIITQLFFQADTFFNFV 234
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C IGITCPI+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 235 KACTAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 294
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MCK+++A G + +H YTLN E + + +L LG+ E
Sbjct: 295 LAVTMCKELLASGLVPGLHFYTLNREVATMEVLKRLGMWNE 335
[41][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 149 bits (376), Expect = 1e-34
Identities = 72/170 (42%), Positives = 108/170 (63%), Gaps = 4/170 (2%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AG+PE HP D G ++ +LK K+DAGAD +++Q FYD ++FL +V
Sbjct: 133 FGIGVAGHPEGHPSSQKGDN-----GKALEMQHLKEKLDAGADFVISQFFYDVNVFLDYV 187
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR++GI CPI+PGIMP+ +Y ++MT FC +P+ +M L I+ ++EAVK G
Sbjct: 188 KRCRKVGIDCPIIPGIMPVQSYSSLVKMTQFCGISVPSAVMDRLSNIRLDDEAVKQVGCK 247
Query: 362 LGTEMCKKIMAHGIKT----VHLYTLNMEKSALAILMSLGLIEESKISRS 499
+ EMC++I++ G++ H YTLN+E+S IL SLG S+ +RS
Sbjct: 248 IVAEMCEQILSAGLEVDVDGFHFYTLNLERSTTRILTSLGAGSISEQARS 297
[42][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 149 bits (376), Expect = 1e-34
Identities = 71/163 (43%), Positives = 104/163 (63%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ E K + YLK KVDAGAD I+TQ+FYD D F+++
Sbjct: 149 FDIGVAGYPEGHPE---------EEASPKLVQYLKEKVDAGADFIITQMFYDADNFIEWC 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GI PI+PGIMPI Y F+R + +C+ +P MA L+P+KD+++AV+ G
Sbjct: 200 RQVRAAGIEVPIIPGIMPITTYAAFLRRSSWCQINVPEAFMAKLDPVKDDDQAVREVGTE 259
Query: 362 LGTEMCKKIMAHGIKT-VHLYTLNMEKSALAILMSLGLIEESK 487
L +MC+K++ G T +H+YT+N+EK+ + +L LGL+ E +
Sbjct: 260 LVAQMCQKLLDSGYVTHLHMYTMNLEKACIMVLDRLGLLSEDE 302
[43][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 148 bits (374), Expect = 2e-34
Identities = 70/161 (43%), Positives = 101/161 (62%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ AE Y+ DL +LK KV AGAD +++QLF+ ++ FLKF+
Sbjct: 192 FDICVAGYPKGHPE---------AESYEADLRHLKEKVFAGADFVISQLFFRSETFLKFM 242
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DC+ IGI CPI+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+
Sbjct: 243 KDCQAIGIACPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVE 302
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G + +H YTLN E + +L LGL E
Sbjct: 303 LAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNE 343
[44][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 148 bits (374), Expect = 2e-34
Identities = 70/161 (43%), Positives = 101/161 (62%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ AE Y+ DL +LK KV AGAD +++QLF+ ++ FLKF+
Sbjct: 192 FDICVAGYPKGHPE---------AESYEADLRHLKEKVFAGADFVISQLFFRSETFLKFM 242
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DC+ IGI CPI+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+
Sbjct: 243 KDCQAIGIACPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVE 302
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G + +H YTLN E + +L LGL E
Sbjct: 303 LAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNE 343
[45][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 148 bits (374), Expect = 2e-34
Identities = 71/161 (44%), Positives = 101/161 (62%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP HPD + Y++DL +LK KVDAGAD I+TQLF+ + ++KFV
Sbjct: 179 FTVCVAGYPHGHPD---------SPTYEEDLQHLKEKVDAGADFIITQLFFKAERYVKFV 229
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGI PI+PG+MPI Y + K +IP EI A+EPI+DN+EA++ YG+H
Sbjct: 230 EDCRRIGINVPIIPGVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVH 289
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
M +++ G + +H YTLN E + + IL +GL E
Sbjct: 290 QAVTMIRELFDSGLVNGLHFYTLNREVATIQILKQIGLWTE 330
[46][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 148 bits (373), Expect = 2e-34
Identities = 69/158 (43%), Positives = 103/158 (65%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HPD Y+ DL +LK KVDAGAD I+TQLF++ +IF KF+
Sbjct: 167 FTICVAGYPQGHPD---------CTSYEDDLIHLKEKVDAGADFIITQLFFEPNIFFKFL 217
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGI PI+PG+MPI Y +++ K ++P I+ LEPIK+++EA++ YG+
Sbjct: 218 ADCRRIGIDVPIIPGVMPIQAYASLLQLVKLSKLEVPQYIIDDLEPIKNDDEAIREYGVK 277
Query: 362 LGTEMCKKIM-AHGIKTVHLYTLNMEKSALAILMSLGL 472
L MC++++ + + +H+YTLN E + +L LGL
Sbjct: 278 LAVSMCRELLSSDDVPGIHVYTLNREVATTELLQQLGL 315
[47][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 148 bits (373), Expect = 2e-34
Identities = 69/168 (41%), Positives = 102/168 (60%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AGYP+ HP+ Y+ D+ LK K+D G D +VTQLF+D + + KF+
Sbjct: 173 FGIAVAGYPDGHPE---------CSSYEDDIRRLKEKLDNGGDFVVTQLFFDAETYFKFL 223
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR GIT PI+PGI+PI Y + K +P I+ +E IKDN+EA++ +GI
Sbjct: 224 RDCRNAGITAPIIPGILPIQGYNSLRHLVQLSKLPVPQRILDTIESIKDNDEAIRKFGIV 283
Query: 362 LGTEMCKKIMA-HGIKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
T +CKK++A + +H+YTLN E++ + +L +GL E I +SL
Sbjct: 284 EATNLCKKLLASDDVPGIHVYTLNREEAVVKLLKRVGLWHEESIYKSL 331
[48][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 147 bits (371), Expect = 4e-34
Identities = 68/161 (42%), Positives = 101/161 (62%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ AE ++ DL +LK KV AGAD I+TQLF+ + F++F
Sbjct: 187 FDVCVAGYPKGHPE---------AESFEADLQHLKEKVVAGADFIITQLFFQAETFIRFT 237
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPI+PGI PI Y ++ K ++P EI A +EPIKDN+ A++ YGI
Sbjct: 238 KACAAVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEITAVIEPIKDNDAAIRNYGIE 297
Query: 362 LGTEMCKKIMAHGIKT-VHLYTLNMEKSALAILMSLGLIEE 481
L MC++++ G+ + +H YTLN E + + +L LG+ E
Sbjct: 298 LAVTMCRELLVSGVVSGLHFYTLNREVATVEVLKRLGIWNE 338
[49][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 147 bits (371), Expect = 4e-34
Identities = 71/160 (44%), Positives = 106/160 (66%), Gaps = 1/160 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYPE H + G + + YLK KVDAGAD I+TQ+FYD D+FLK+
Sbjct: 150 FDVGVAGYPEGHEEASGAELIG----------YLKEKVDAGADFIITQMFYDADLFLKWC 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R GI+ PI+PGIMPI +Y +R +C+ ++P E + LEP+KD+++AV+ G
Sbjct: 200 DAVRAAGISVPIIPGIMPITSYAALLRRAKWCQVRLPPEFLERLEPVKDDDQAVREIGTV 259
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIE 478
L +MC+KI+A G + +HLYT+N+E+++L IL L LI+
Sbjct: 260 LVADMCRKILASGHVTHLHLYTMNLERASLMILERLQLID 299
[50][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 146 bits (369), Expect = 6e-34
Identities = 70/161 (43%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 213 FDICVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 263
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 264 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 323
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++A G + +H YTLN E + +L LG+ E
Sbjct: 324 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 364
[51][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 146 bits (369), Expect = 6e-34
Identities = 70/161 (43%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 231 FDICVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 281
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 282 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 341
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++A G + +H YTLN E + +L LG+ E
Sbjct: 342 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 382
[52][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 146 bits (369), Expect = 6e-34
Identities = 70/161 (43%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 190 FDICVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 240
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 241 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 300
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++A G + +H YTLN E + +L LG+ E
Sbjct: 301 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 341
[53][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 146 bits (369), Expect = 6e-34
Identities = 70/161 (43%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 220 FDICVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 270
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 271 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 330
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++A G + +H YTLN E + +L LG+ E
Sbjct: 331 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 371
[54][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 145 bits (365), Expect = 2e-33
Identities = 69/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 213 FDLCVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 263
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 264 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 323
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C +++A G + +H YTLN E + +L LG+ E
Sbjct: 324 LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 364
[55][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 145 bits (365), Expect = 2e-33
Identities = 69/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 231 FDLCVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 281
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 282 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 341
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C +++A G + +H YTLN E + +L LG+ E
Sbjct: 342 LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 382
[56][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 145 bits (365), Expect = 2e-33
Identities = 72/166 (43%), Positives = 108/166 (65%), Gaps = 2/166 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ + KDL YLK K+DAG I+TQ+FYD D F+++
Sbjct: 151 FDIGVAGYPEGHPE---------EKERHKDLVYLKEKIDAGGSFIITQMFYDVDNFIQWC 201
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++ R++GI PI+PGIMPI Y F+R + + KIP + LEP+KD+++ V+ G
Sbjct: 202 HEVREMGIDVPIIPGIMPITTYAAFLRRAQWGQIKIPQAFLDVLEPVKDDDQLVRDKGSE 261
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI-EESKIS 493
L +MC+KI+ G +K +H+YT+N+EK+ L IL LGL+ ES+++
Sbjct: 262 LIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILEKLGLLPSESEVN 307
[57][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 145 bits (365), Expect = 2e-33
Identities = 74/163 (45%), Positives = 101/163 (61%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ E QK L YLK K DAGAD I+TQ+FYD D F+ +
Sbjct: 146 FNIGVAGYPEGHPE---------EEDEQKTLRYLKEKCDAGADFIITQMFYDVDNFISWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IG+ PI+PGIMPI+ Y FIR + + IP + AL+PIKD++ V+ G
Sbjct: 197 SKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIAIPQHFLDALDPIKDDDFLVRERGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC K++ G + +H YT+N+EK+ + IL L LIE K
Sbjct: 257 LVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIK 299
[58][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 144 bits (363), Expect = 3e-33
Identities = 68/158 (43%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HPD + ++ DL YLK KV AGAD I+TQLF++ D F FV
Sbjct: 189 FDVCVAGYPKGHPD---------SGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFV 239
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGITCPI+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 240 KACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDGAIRNYGID 299
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
+C++++A G + +H YTLN E + +L LG+
Sbjct: 300 QAVSLCQQLLASGLVPGLHFYTLNREVATTEVLKRLGM 337
[59][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 144 bits (363), Expect = 3e-33
Identities = 68/158 (43%), Positives = 96/158 (60%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HPD A ++ DL YLK KV AGAD I+TQLF++ D F FV
Sbjct: 315 FDICVAGYPKGHPD---------AGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFV 365
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGITCPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 366 KACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIE 425
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
+C++++ G + +H YTLN E + +L LG+
Sbjct: 426 QAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGM 463
[60][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 144 bits (363), Expect = 3e-33
Identities = 68/158 (43%), Positives = 96/158 (60%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HPD A ++ DL YLK KV AGAD I+TQLF++ D F FV
Sbjct: 231 FDICVAGYPKGHPD---------AGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFV 281
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGITCPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 282 KACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIE 341
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
+C++++ G + +H YTLN E + +L LG+
Sbjct: 342 QAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGM 379
[61][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 144 bits (363), Expect = 3e-33
Identities = 68/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 230 FDICVAGYPRGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFV 280
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGI+CPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 281 KACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIE 340
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 341 LAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[62][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 144 bits (363), Expect = 3e-33
Identities = 68/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 230 FDICVAGYPRGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFV 280
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGI+CPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 281 KACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIE 340
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 341 LAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[63][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 144 bits (363), Expect = 3e-33
Identities = 68/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 230 FDICVAGYPRGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFV 280
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGI+CPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 281 KACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIE 340
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 341 LAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[64][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 144 bits (363), Expect = 3e-33
Identities = 70/158 (44%), Positives = 104/158 (65%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AGYP HP+ A Y+ DL YLK+KVDAGAD I++Q+ +D ++F F+
Sbjct: 201 FTIACAGYPAGHPE---------APSYRADLLYLKAKVDAGADFIISQIIFDGEVFKNFL 251
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGI+PI +Y+ R+ + IP I+ +LEPIK++++AV+ +GI
Sbjct: 252 RDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSILTSLEPIKNDDDAVRNFGIW 311
Query: 362 LGTEMCKKIMAHGIKT-VHLYTLNMEKSALAILMSLGL 472
+C+ ++++G T +HL+TLN E S+ IL LGL
Sbjct: 312 HAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGL 349
[65][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 144 bits (363), Expect = 3e-33
Identities = 68/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 189 FDICVAGYPRGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFV 239
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGI+CPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 240 KACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIE 299
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 300 LAVRLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 340
[66][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 144 bits (362), Expect = 4e-33
Identities = 74/163 (45%), Positives = 103/163 (63%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ E K L YLK K DAGA+LI+TQ+FYD D F+K+
Sbjct: 146 FNIGVAAYPEGHPE---------EEDEDKTLQYLKEKCDAGANLIITQMFYDADNFIKWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IGI PI+PGIMPI+ Y FIR + + IP + ALEPIK+++ V+A G
Sbjct: 197 SKLRKIGIDIPIIPGIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC K++ G + +H YT+N+E++ + IL +L LIE K
Sbjct: 257 LVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVK 299
[67][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 144 bits (362), Expect = 4e-33
Identities = 74/158 (46%), Positives = 101/158 (63%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AGYP HP A Y+ DL YLK+K DAGA+ ++TQLF++ + F KFV
Sbjct: 182 FSIGCAGYPLGHPQ---------APSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFV 232
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG
Sbjct: 233 RDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTE 292
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
EMC++++ +G ++HLYT+N E S IL SLGL
Sbjct: 293 RCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSLGL 330
[68][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 144 bits (362), Expect = 4e-33
Identities = 74/178 (41%), Positives = 105/178 (58%), Gaps = 21/178 (11%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGN-------------------DGLAPAEG--YQKDLAYLKSKVD 118
F I ++GYPE HP+ I DGL +QK++ YLK+KVD
Sbjct: 149 FSIAVSGYPEGHPNAITKVQDEAELTESERERVIEMEDGLYVCRDGDFQKEMEYLKAKVD 208
Query: 119 AGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAE 298
AGADLI+TQ+ +D ++ F+ C+ GI P+VPGIM I N GF RMT FCK++ PA
Sbjct: 209 AGADLIITQMVFDAPVYGAFLKACKAYGINIPVVPGIMCIQNAGGFKRMTAFCKSRTPAA 268
Query: 299 IMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ AA+E D++EA++ + G ++C+ + A G +H YTLN+EK LAIL +L L
Sbjct: 269 LRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAGAPGLHFYTLNLEKVTLAILDALNL 326
[69][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 144 bits (362), Expect = 4e-33
Identities = 73/159 (45%), Positives = 100/159 (62%), Gaps = 2/159 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AG+PE HP+ I +G + +L LK K++AGAD I TQ+FYD DIF K+V
Sbjct: 162 FAIAVAGFPEGHPEAI--------DGPELELERLKEKIEAGADFIFTQMFYDFDIFAKWV 213
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
D R GI CPI+PG+MPI Y GF R T T +P AL+P++D+++ V+ G
Sbjct: 214 KDVRAAGINCPIIPGVMPIQTYGGFQRATARFGTLVPQYFHDALDPVRDDDQKVREIGTR 273
Query: 362 LGTEMCKKIMAH--GIKTVHLYTLNMEKSALAILMSLGL 472
L EMCKKI+ GI +H+YT+N+EK + +L LGL
Sbjct: 274 LVGEMCKKIVGTGLGISGLHIYTMNLEKGSRMLLDYLGL 312
[70][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 144 bits (362), Expect = 4e-33
Identities = 74/163 (45%), Positives = 103/163 (63%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ E K L YLK K DAGA+LI+TQ+FYD D F+K+
Sbjct: 146 FNIGVAAYPEGHPE---------EEDEDKTLQYLKEKCDAGANLIITQMFYDADNFIKWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IGI PI+PGIMPI+ Y FIR + + IP + ALEPIK+++ V+A G
Sbjct: 197 SKLRKIGIDIPIIPGIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC K++ G + +H YT+N+E++ + IL +L LIE K
Sbjct: 257 LVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVK 299
[71][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 144 bits (362), Expect = 4e-33
Identities = 69/161 (42%), Positives = 98/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ A ++ DL +LK KV AGAD I+TQLF++ D F +FV
Sbjct: 190 FDLCVAGYPKGHPE---------AGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 240
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +GITCPIVPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI
Sbjct: 241 KACTDMGITCPIVPGIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 300
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C +++A G + +H YTLN E + +L LG+ E
Sbjct: 301 LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTE 341
[72][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 144 bits (362), Expect = 4e-33
Identities = 74/158 (46%), Positives = 101/158 (63%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AGYP HP A Y+ DL YLK+K DAGA+ ++TQLF++ + F KFV
Sbjct: 203 FSIGCAGYPLGHPQ---------APSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFV 253
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG
Sbjct: 254 RDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTE 313
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
EMC++++ +G ++HLYT+N E S IL SLGL
Sbjct: 314 RCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSLGL 351
[73][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 143 bits (361), Expect = 5e-33
Identities = 66/158 (41%), Positives = 99/158 (62%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ E ++ DL +LK KV AGAD I+TQLF++ + F +FV
Sbjct: 189 FDVCVAGYPKGHPE---------GESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFV 239
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGITCPI+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 240 KACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIE 299
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
+C++++A G + +H YTLN E + + +L LGL
Sbjct: 300 QAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGL 337
[74][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 143 bits (360), Expect = 7e-33
Identities = 68/161 (42%), Positives = 97/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 195 FDICVAGYPKGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASSFFSFV 245
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C IGI+CPI+PGI PI Y ++ K ++P I +EPIKDN+ A++ YGI
Sbjct: 246 KACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIE 305
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 306 LAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 346
[75][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 143 bits (360), Expect = 7e-33
Identities = 68/161 (42%), Positives = 97/161 (60%), Gaps = 1/161 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP+ HPD AE ++ DL +LK KV AGAD I+TQLF++ F FV
Sbjct: 230 FDICVAGYPKGHPD---------AESFEDDLKHLKEKVSAGADFIITQLFFEASSFFSFV 280
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C IGI+CPI+PGI PI Y ++ K ++P I +EPIKDN+ A++ YGI
Sbjct: 281 KACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIE 340
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
L +C++++ G + +H YTLN E + + +L LG+ E
Sbjct: 341 LAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[76][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 143 bits (360), Expect = 7e-33
Identities = 70/168 (41%), Positives = 106/168 (63%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ +D L L +LK KVD GAD +VTQ+FYD D FL +
Sbjct: 151 FDIGVAAYPEGHPECDCDDKL---------LLHLKEKVDCGADFMVTQMFYDVDKFLDWC 201
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GI+ PI+PGIMPI +Y FIR T +C+ +P + LEP+KD+++ V+ G
Sbjct: 202 ARVREAGISIPIIPGIMPITSYPSFIRRTQWCQINVPDNFLELLEPVKDDDQLVRDVGTE 261
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESKISRSL 502
L E+C+K++ G + +H+YT+N+EK++L IL L L++ S + + +
Sbjct: 262 LMVELCQKLLDSGYVNHLHMYTMNLEKASLMILEKLDLLKRSNVGKDV 309
[77][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 143 bits (360), Expect = 7e-33
Identities = 77/165 (46%), Positives = 99/165 (60%), Gaps = 1/165 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD +E ++D + K+K DAGAD IVTQLFYD D+FL++V
Sbjct: 149 FCIGVAGYPNPHPD---------SESEEEDFKWFKAKCDAGADFIVTQLFYDVDVFLEWV 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI NY F R+ K +P I + L+PI ++ VK YG
Sbjct: 200 KTCRARGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSITSDLQPISSDDATVKRYGAE 259
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESKIS 493
L T+M +I+ G + VHL TLN+EKS IL +LG SK S
Sbjct: 260 LATKMVSQIIESGLVPGVHLCTLNLEKSVRMILDNLGWSAASKTS 304
[78][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 143 bits (360), Expect = 7e-33
Identities = 75/162 (46%), Positives = 102/162 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCDDQDDPELL---------MEHLKEKVDAGGTFIITQMFYDVDNFLTWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CRQ GIT PI+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G
Sbjct: 197 EKCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +MCKKI+A GI +H YT+N++++ IL LGLI K
Sbjct: 257 LVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHK 298
[79][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 143 bits (360), Expect = 7e-33
Identities = 65/158 (41%), Positives = 99/158 (62%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYP+ HP+ E ++ DL +LK KV AGAD I+TQLF++ + F +FV
Sbjct: 189 FDVCVAGYPKGHPE---------GESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFV 239
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGITCP++PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI
Sbjct: 240 KACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIE 299
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
+C++++A G + +H YTLN E + + +L LGL
Sbjct: 300 QAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGL 337
[80][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 142 bits (359), Expect = 9e-33
Identities = 75/162 (46%), Positives = 102/162 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCDDQDDPELL---------MEHLKEKVDAGGTFIITQMFYDVDNFLTWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CRQ GIT PI+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G
Sbjct: 197 ERCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +MCKKI+A GI +H YT+N++++ IL LGLI K
Sbjct: 257 LVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHK 298
[81][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 142 bits (359), Expect = 9e-33
Identities = 74/157 (47%), Positives = 98/157 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G E + + YLK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPE---------GCEDEEDPELLMKYLKEKVDAGGTFIITQMFYDADNFLDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR+ GIT PI+PGIMPI+ Y FIR T + K KIP M ALEP+K+++ AVK G
Sbjct: 197 KRCRKAGITVPIIPGIMPISTYAAFIRRTNWVKCKIPKGWMEALEPVKNDDAAVKQIGRA 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
L +EMC+K++ +GI +H YT+N+ +S +L L L
Sbjct: 257 LVSEMCRKLLDNGINHLHFYTMNLAQSTTMVLEELNL 293
[82][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 142 bits (359), Expect = 9e-33
Identities = 73/163 (44%), Positives = 101/163 (61%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ E QK L YLK K DAGAD I+TQ+FYD + F+ +
Sbjct: 146 FNIGVAGYPEGHPE---------EEDEQKTLQYLKEKCDAGADFIITQMFYDVENFVSWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IG+ PI+PGIMPI+ Y FIR + + IP + AL+PIKD++ V+ G
Sbjct: 197 SKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIVIPQHFLDALDPIKDDDFLVRERGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC K++ G + +H YT+N+EK+ + IL L LIE K
Sbjct: 257 LVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIK 299
[83][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 142 bits (358), Expect = 1e-32
Identities = 71/163 (43%), Positives = 101/163 (61%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + L L YLK KVDAGAD I+TQ+FYD D F+ +
Sbjct: 149 FNIGVAAYPEGHPEEQNSPNL---------LKYLKEKVDAGADFIITQMFYDVDNFIAWC 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++GIT PI+PGIMPI+ Y FIR + + IP + AL PIK+++ A++ G
Sbjct: 200 AKLRELGITIPIIPGIMPISTYSAFIRRANWSQVAIPQHFLDALNPIKEDDYAIREVGTQ 259
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC+K++ G + +H YT+N+E+S + IL L L+E K
Sbjct: 260 LVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEKLNLVESIK 302
[84][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 142 bits (357), Expect = 2e-32
Identities = 73/158 (46%), Positives = 101/158 (63%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AGYP HP A Y+ DL YLK+K DAGA+ ++TQLF++ + F KFV
Sbjct: 204 FSIGCAGYPLGHPQ---------APSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFV 254
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG
Sbjct: 255 ADCREIGITKPIIPGIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTE 314
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
EMC++++ +G ++HLYT+N E S IL +LGL
Sbjct: 315 RCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKALGL 352
[85][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 142 bits (357), Expect = 2e-32
Identities = 73/158 (46%), Positives = 101/158 (63%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AGYP HP A Y+ DL YLK+K DAGA+ ++TQLF++ + F KFV
Sbjct: 254 FSIGCAGYPLGHPQ---------APSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFV 304
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR+IGIT PI+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG
Sbjct: 305 ADCREIGITKPIIPGIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTE 364
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
EMC++++ +G ++HLYT+N E S IL +LGL
Sbjct: 365 RCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKALGL 402
[86][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 142 bits (357), Expect = 2e-32
Identities = 75/169 (44%), Positives = 106/169 (62%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ I+TQ+FYDTD F+++V
Sbjct: 146 FDIGVGGYPEGADDNPDVDLL---------IDHLKEKVDAGSSFIITQMFYDTDNFIEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GIT PI+PGIMPI+ Y FIR + K +IP E + ALEP+K+++ AVK G
Sbjct: 197 KKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPEWLEALEPVKNDDAAVKEIGKR 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L EMC+K++A G+ +H YT+N+ ++ ++L L LI EE+ + R L
Sbjct: 257 LIAEMCRKLLAAGLNHLHFYTMNLAQATQSVLDELKLIPSEETPLQRPL 305
[87][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 141 bits (355), Expect = 3e-32
Identities = 73/169 (43%), Positives = 106/169 (62%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ ++TQ+FYD D F+++V
Sbjct: 146 FDIGVGGYPEGADDNPDVDQL---------IDHLKEKVDAGSSFVITQMFYDIDNFIEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GIT PI+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G
Sbjct: 197 KKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKR 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L +MC++++A GIK +H YT+N+ ++ A+L L LI EE+ + R L
Sbjct: 257 LVADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPL 305
[88][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 140 bits (353), Expect = 5e-32
Identities = 71/161 (44%), Positives = 99/161 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G +P + + + +LK KVD GAD IVTQ+FYD D F+ +V
Sbjct: 146 FCIGVAGYPE---------GYSPDDDIDESIKHLKLKVDEGADFIVTQMFYDVDNFIAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R GI PI PGIMPI + FIR + KIP M L P+KD++E V+ G+
Sbjct: 197 DKVRAAGINIPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDTLVPVKDDDEGVRERGVE 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEES 484
L EMC+K++A GI +H YT+N+EK+ I+ LGL++E+
Sbjct: 257 LIVEMCRKLIASGITRLHFYTMNLEKAVKMIIERLGLLDEN 297
[89][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 140 bits (352), Expect = 6e-32
Identities = 74/163 (45%), Positives = 102/163 (62%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ D L K L YLK K DAGA+ I+TQ+FYD D F+ +
Sbjct: 146 FNIGVAGYPEGHPEE--TDEL-------KTLEYLKEKCDAGANFIITQMFYDADNFISWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IGI PI+PGIMPI+ Y F+R + + IP + AL+PIKD++ V+ G
Sbjct: 197 SKLRKIGIDLPIIPGIMPISTYSAFLRRAKWSEIAIPQHFLDALDPIKDDDYLVREKGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC+K++ G I +H YT+N+EK+ + IL L LIE K
Sbjct: 257 LVSEMCQKLLESGYINHLHFYTMNLEKATVMILEKLNLIEAVK 299
[90][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 140 bits (352), Expect = 6e-32
Identities = 73/162 (45%), Positives = 101/162 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCDDQDDPDLL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
N CR+ GIT PI+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G
Sbjct: 197 NKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
L MC+KI+A GI +H YT+N++++ +L L LI K
Sbjct: 257 LVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHK 298
[91][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 139 bits (351), Expect = 8e-32
Identities = 72/169 (42%), Positives = 105/169 (62%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ ++TQ+FYD D F+++V
Sbjct: 146 FDIGVGGYPEGADDNPDVDQL---------IDHLKEKVDAGSSFVITQMFYDVDNFIEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GIT PI+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G
Sbjct: 197 KKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKR 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L +MC++++A GI +H YT+N+ ++ A+L L LI EE+ + R L
Sbjct: 257 LVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPL 305
[92][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 139 bits (351), Expect = 8e-32
Identities = 72/169 (42%), Positives = 105/169 (62%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ ++TQ+FYD D F+++V
Sbjct: 146 FDIGVGGYPEGADDNPDVDQL---------IDHLKEKVDAGSSFVITQMFYDVDNFIEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GIT PI+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G
Sbjct: 197 KKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKR 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L +MC++++A GI +H YT+N+ ++ A+L L LI EE+ + R L
Sbjct: 257 LVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPL 305
[93][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 139 bits (351), Expect = 8e-32
Identities = 68/172 (39%), Positives = 106/172 (61%), Gaps = 5/172 (2%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKD----LAYLKSKVDAGADLIVTQLFYDTDIF 169
F I +AGYPE +G Q D L +LK KV+ GAD I+TQ+FYD D F
Sbjct: 139 FAIGVAGYPEG-------------DGEQADQRLLLQHLKEKVECGADFIITQMFYDVDNF 185
Query: 170 LKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKA 349
L++V+ R++G+T PI+PGIMPI+ Y F+R +C ++P + L P+ D++E V+
Sbjct: 186 LRWVHGLREVGVTVPIIPGIMPISTYAAFLRRCSWCGVRVPDNFLQRLAPVSDDDELVRE 245
Query: 350 YGIHLGTEMCKKIMAHGIKT-VHLYTLNMEKSALAILMSLGLIEESKISRSL 502
G L +MC++++ G+ + +HLYT+N+E+ L IL LGL+ E+ +S+
Sbjct: 246 IGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPLVILERLGLLPEASAEQSI 297
[94][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 139 bits (350), Expect = 1e-31
Identities = 72/162 (44%), Positives = 100/162 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G E + + +LK KVDAG I+TQ+FYD DIFL +V
Sbjct: 146 FDIGVAGYPE---------GCEDQEDPELLMTHLKEKVDAGGTFIITQMFYDVDIFLDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR+ GI PI+PGIMPI+ Y F+R + + K ++P M ALEP K+++ AVK G
Sbjct: 197 KRCREQGIKVPILPGIMPISTYAAFLRRSNWVKCRVPPSWMEALEPCKNDDAAVKQIGKK 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC+KI+ GI+ +H YT+N+ +S +L L LI S+
Sbjct: 257 LVSEMCRKILDSGIRHLHFYTMNLAQSTKMVLEELDLIPSSE 298
[95][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 139 bits (350), Expect = 1e-31
Identities = 71/163 (43%), Positives = 100/163 (61%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ E K L YLK K DAGA+ I+TQ+FYD D F+ +
Sbjct: 147 FNIGVAAYPEGHPE---------EEDESKTLHYLKEKCDAGANFIITQMFYDVDNFISWC 197
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+IG+ PI+PGIMPI+ Y FIR + + KIP + ALEPIKD++ V+ G
Sbjct: 198 AKLRKIGVEIPIIPGIMPISTYAAFIRRAKWSEIKIPPHFLEALEPIKDDDFLVREKGTE 257
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L +EMC++++ G + +H YT+N+EK+ + IL L L+E K
Sbjct: 258 LVSEMCQQLIESGYVNHLHFYTMNLEKATVMILEKLNLVEAIK 300
[96][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 139 bits (349), Expect = 1e-31
Identities = 67/159 (42%), Positives = 100/159 (62%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP++ P + + DL YLK K+DAG D I+TQ+FYD D F+ +
Sbjct: 149 FAIGVAGYPECHPEL-------PNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWC 201
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R G+ PI+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +
Sbjct: 202 SQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTN 261
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI 475
L EMC+K++ G + +H+YT+N+EK+ L IL L ++
Sbjct: 262 LIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL 300
[97][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 139 bits (349), Expect = 1e-31
Identities = 76/169 (44%), Positives = 102/169 (60%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ IVTQ+FYDTD F+K+V
Sbjct: 146 FCIGVGGYPEGADDNSDVDQL---------IDHLKEKVDAGSSFIVTQMFYDTDNFIKWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI Y FIR + KT IP + + ALEP+K+++ AVK G
Sbjct: 197 EKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKTHIPPDWLEALEPVKNDDAAVKQVGKR 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL--IEESKISRSL 502
L +MC++++A GIK +H YT+N+ +S +L L L E+ I R L
Sbjct: 257 LIADMCRRLIASGIKHLHFYTMNLAQSTQLVLEELELTPTAEAPIPRPL 305
[98][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 139 bits (349), Expect = 1e-31
Identities = 67/159 (42%), Positives = 100/159 (62%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP++ P + + DL YLK K+DAG D I+TQ+FYD D F+ +
Sbjct: 149 FAIGVAGYPECHPEL-------PNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWC 201
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R G+ PI+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +
Sbjct: 202 SQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTN 261
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI 475
L EMC+K++ G + +H+YT+N+EK+ L IL L ++
Sbjct: 262 LIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL 300
[99][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 139 bits (349), Expect = 1e-31
Identities = 67/159 (42%), Positives = 100/159 (62%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP++ P + + DL YLK K+DAG D I+TQ+FYD D F+ +
Sbjct: 149 FAIGVAGYPECHPEL-------PNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWC 201
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R G+ PI+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +
Sbjct: 202 SQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTN 261
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI 475
L EMC+K++ G + +H+YT+N+EK+ L IL L ++
Sbjct: 262 LIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL 300
[100][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 137 bits (346), Expect = 3e-31
Identities = 67/151 (44%), Positives = 90/151 (59%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I A YPE HP+ G G D+ YLK K D GAD VTQ F+D D F +F
Sbjct: 101 FSIACATYPEGHPESAG--------GVADDIRYLKLKQDNGADAAVTQYFFDNDAFFRFR 152
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR GIT PI+PGIMPI NY +R + C IPA + ++PI+D+ EAVKA GI
Sbjct: 153 DACRAAGITLPIIPGIMPIGNYDQIVRFSSMCGASIPAWLHEQMQPIRDDLEAVKALGIE 212
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
L + C++++ G+ +H YTLN ++ +AI
Sbjct: 213 LAAKQCRELLQAGVPGLHFYTLNKSEATIAI 243
[101][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 137 bits (345), Expect = 4e-31
Identities = 71/158 (44%), Positives = 99/158 (62%)
Frame = +2
Query: 14 IAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVNDCR 193
+AGYPE D D L + +LK KVDAG I+TQ+FYD D FL +VN CR
Sbjct: 41 VAGYPEGCDDQDDPDLL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWVNKCR 91
Query: 194 QIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTE 373
+ GIT PI+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G L
Sbjct: 92 ENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVAN 151
Query: 374 MCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
MC+KI+A GI +H YT+N++++ +L L LI K
Sbjct: 152 MCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHK 189
[102][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 137 bits (345), Expect = 4e-31
Identities = 72/172 (41%), Positives = 108/172 (62%), Gaps = 5/172 (2%)
Frame = +2
Query: 2 FGITIAGYPEA---HPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFL 172
F I + GYPE +PDV ++ + +LK KVDAGA ++TQ+FYDTD F+
Sbjct: 146 FDIGVGGYPEGADDNPDV------------EQLIDHLKEKVDAGASFVITQMFYDTDNFI 193
Query: 173 KFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAY 352
+V CR GI PI+PGIMPI Y FIR + + KT+IP + + ALEP+K+++ AV+
Sbjct: 194 GWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEALEPVKNDDAAVRDI 253
Query: 353 GIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
G L +MC++++A GI +H YT+N+ +S +L L L+ EE+ + R+L
Sbjct: 254 GKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETPLQRAL 305
[103][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 136 bits (343), Expect = 7e-31
Identities = 72/169 (42%), Positives = 103/169 (60%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ +VTQ+FYD + F+++V
Sbjct: 146 FDIGVGGYPEGADDNTDVDQL---------IDHLKEKVDAGSSFVVTQMFYDAENFIEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI Y FIR + + K K+P+E M ALEP+K+++ AV+ G
Sbjct: 197 KKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMEALEPVKNDDSAVRDIGKT 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L MC++++A GIK +H YT+N+ ++ +L L L E+S I R L
Sbjct: 257 LIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSPIQRPL 305
[104][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 136 bits (343), Expect = 7e-31
Identities = 74/167 (44%), Positives = 97/167 (58%), Gaps = 1/167 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE I D + D+ LK+K +AGA IVTQLFYD D +++
Sbjct: 171 FCIGVAGYPEGLKQGIDCD-------MRHDIKVLKAKQEAGAHFIVTQLFYDVDALVRWT 223
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+CR GIT PI+PGIMPI NY F RM C P +++ LEPIK ++ VK +GIH
Sbjct: 224 KECRAAGITIPIIPGIMPIQNYTMFRRMANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIH 283
Query: 362 LGTEMCKKIMAH-GIKTVHLYTLNMEKSALAILMSLGLIEESKISRS 499
L +M K I GI+ HLYTLN+EKSA ++ L + + S S
Sbjct: 284 LSIDMIKSIREQTGIRAFHLYTLNLEKSATCVIKVLADVPDQSASIS 330
[105][TOP]
>UniRef100_UPI00005884BD PREDICTED: similar to Mthfr-prov protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI00005884BD
Length = 326
Score = 136 bits (342), Expect = 9e-31
Identities = 63/129 (48%), Positives = 81/129 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD + Y+ DL LK KVDAGAD I+TQLF++ FLKFV
Sbjct: 205 FVIAVAGYPSGHPDAVS---------YEDDLKCLKEKVDAGADFIITQLFFEAKTFLKFV 255
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR IGIT PI+PG+MPI Y + K +P EIM +EPIK+N+ A++ YG+H
Sbjct: 256 RDCRAIGITVPIIPGVMPIQGYHSLRSLVKLSKLDVPQEIMDVIEPIKENDAAIRNYGVH 315
Query: 362 LGTEMCKKI 388
MCK++
Sbjct: 316 QAVTMCKEL 324
[106][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 136 bits (342), Expect = 9e-31
Identities = 70/158 (44%), Positives = 99/158 (62%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE P+ D L + +LK KVDAG IVTQ+FYDTD FLK+V
Sbjct: 147 FDIGVAAYPEGTPEEPDVDIL---------IDHLKEKVDAGGTFIVTQMFYDTDNFLKWV 197
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR GI PI+PGIMPI+ Y F+R +C+ +IP + + LEP+KD++ V+ G
Sbjct: 198 DKCRAKGINVPIIPGIMPISTYASFMRRANWCQIQIPQDFLDQLEPVKDDDMRVRELGTQ 257
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
L +MC+K++ G IK +H YT+N+EK+ + +L L L
Sbjct: 258 LVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERLNL 295
[107][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 136 bits (342), Expect = 9e-31
Identities = 70/158 (44%), Positives = 97/158 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G E + + +LK KVDAG I+TQ+FYD DIFL +V
Sbjct: 146 FDIGVAGYPE---------GCEDEEDPETLMKHLKEKVDAGGTFIITQMFYDVDIFLDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR+ GI PI+PGIMPI+ Y F+R + + K K+P M ALEP+K+++ AVK G
Sbjct: 197 KRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKK 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L MC+KI+ GI+ +H YT+N+ ++ +L L LI
Sbjct: 257 LVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLI 294
[108][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 136 bits (342), Expect = 9e-31
Identities = 70/158 (44%), Positives = 97/158 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G E + + +LK KVDAG I+TQ+FYD DIFL +V
Sbjct: 146 FDIGVAGYPE---------GCEDEEDPETLMKHLKEKVDAGGTFIITQMFYDVDIFLDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR+ GI PI+PGIMPI+ Y F+R + + K K+P M ALEP+K+++ AVK G
Sbjct: 197 KRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKK 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L MC+KI+ GI+ +H YT+N+ ++ +L L LI
Sbjct: 257 LVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLI 294
[109][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 135 bits (341), Expect = 1e-30
Identities = 66/163 (40%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + K L YLK K D GAD I+TQ+FYD D F+ +
Sbjct: 146 FNIGVAAYPEGHPE---------EDSEAKTLEYLKEKCDVGADFIITQMFYDVDNFISWC 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IG+ PI+PGIMPI+ Y F+R + + IP + LEPIKD++ V+ G
Sbjct: 197 SKIRKIGVNIPIIPGIMPISTYAAFVRRAKWSQIAIPPHFLEVLEPIKDDDYLVREKGTE 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESK 487
L ++MC K++ G + +H YT+N+E++ + IL +L +IE K
Sbjct: 257 LVSQMCTKLLQSGFVNHLHFYTMNLERATIMILETLNIIEPVK 299
[110][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 135 bits (340), Expect = 1e-30
Identities = 70/158 (44%), Positives = 99/158 (62%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCEDQDDPELL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+CR+ GI PI+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G
Sbjct: 197 KNCREKGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L MCKK++A GI +H YT+N++++ +L LGLI
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLI 294
[111][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 134 bits (338), Expect = 3e-30
Identities = 65/159 (40%), Positives = 98/159 (61%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP+ G+D + L +LK KVDAGA+ I+TQ+FYD D+F+K+
Sbjct: 149 FDIGVAGYPEGHPETAGDD--------ETLLDHLKEKVDAGANFIITQMFYDADLFIKWC 200
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R G+ P++PGIMPI Y F+R +C IP E L+PIKD+++ V+ G
Sbjct: 201 QRVRAKGVDVPLIPGIMPITTYAAFLRRANWCDVHIPQEYFDRLDPIKDDDQLVREVGTD 260
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI 475
L +C+K++ G + +H+YT+N+EK+ IL + L+
Sbjct: 261 LIVSLCQKLLDSGYVSHLHIYTMNLEKAPQMILDRMELL 299
[112][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 134 bits (337), Expect = 3e-30
Identities = 72/169 (42%), Positives = 101/169 (59%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ IVTQ+FYDTD F+ +V
Sbjct: 146 FDIGVGGYPEGADDNPDVDLL---------IDHLKEKVDAGSSFIVTQMFYDTDNFINWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI Y F+R + K +IP E + ALEP+K+++ AVK G
Sbjct: 197 KKCRAKGINVPIIPGIMPIQTYAAFMRRANWTKIRIPPEWLEALEPVKNDDAAVKEIGKG 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L +MC++++A GI +H YT+N+ +S +L L L EE+ + + L
Sbjct: 257 LIADMCRRLLAAGINHLHFYTMNLAQSTQLVLEELNLTPSEETPLQKPL 305
[113][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 134 bits (337), Expect = 3e-30
Identities = 71/169 (42%), Positives = 101/169 (59%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAGA ++TQ+FYDTD+F+ +V
Sbjct: 146 FDIGVGGYPEGADDNPDVDLL---------IDHLKEKVDAGASFVITQMFYDTDLFISWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI Y FIR + K IP + + LEP+K+++ AVK G
Sbjct: 197 KKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETLEPVKNDDAAVKEIGKV 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L +MC++++A GI +H YT+N+ ++ +L L L+ EE+ I R L
Sbjct: 257 LIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETPIQRPL 305
[114][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 134 bits (336), Expect = 4e-30
Identities = 70/158 (44%), Positives = 97/158 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCEDQDDPELL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G
Sbjct: 197 KKCRDKGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L MCKK++A GI +H YT+N++++ +L LGLI
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLI 294
[115][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 134 bits (336), Expect = 4e-30
Identities = 70/158 (44%), Positives = 97/158 (61%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCEDQDDPELL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI PI+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G
Sbjct: 197 KKCRDNGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L MCKK++A GI +H YT+N++++ +L LGLI
Sbjct: 257 LVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLI 294
[116][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 131 bits (329), Expect = 3e-29
Identities = 71/155 (45%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D + L L +LK KVD GA IVTQ+FYD D FL++V
Sbjct: 146 FDIGVAGYPEGCDDNKDEESL---------LDHLKEKVDMGASFIVTQMFYDVDNFLRWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GIT PI+PGIMPI Y FIR KIP E MA LEP+K+++ AV+ G
Sbjct: 197 KRVRERGITIPIIPGIMPIATYASFIRRANHMNCKIPEEWMAKLEPVKNDDVAVREIGKT 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L EMC+KI+ GI+ +H YT+N+ ++ +L L
Sbjct: 257 LVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEEL 291
[117][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 131 bits (329), Expect = 3e-29
Identities = 65/156 (41%), Positives = 98/156 (62%), Gaps = 1/156 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YP+ H + ++ K++ YLK+KVDAG+D I+TQLFYD D FL+++
Sbjct: 147 FCVGVAAYPDGHTESTTDE--------DKEIDYLKAKVDAGSDFIITQLFYDVDQFLRWL 198
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GIT P++PGIMPI Y F+R+T C T++PA I L PI +++ VK YG+
Sbjct: 199 AKIRSKGITVPVIPGIMPIQTYASFVRLTKLCGTRVPACITEDLAPISHDDQLVKDYGVK 258
Query: 362 LGTEMCKKI-MAHGIKTVHLYTLNMEKSALAILMSL 466
L +M +++ + GI+ H TLN+EKS +L +L
Sbjct: 259 LAVQMIRRLRLEGGIQGFHFCTLNLEKSVQRVLETL 294
[118][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 130 bits (328), Expect = 4e-29
Identities = 70/168 (41%), Positives = 104/168 (61%), Gaps = 3/168 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYP D Y DLA LK +VDAGAD I TQLF++ + F KF
Sbjct: 167 FAIAVTGYPSQRCD-----------WYDSDLALLKREVDAGADFITTQLFFEVETFFKFE 215
Query: 182 NDCRQIGITCPIVPGIMPINNYKGF--IRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYG 355
DCR IGI PI+PGI+PI N + +R F K+P EI+ L+ K++ EA++A+G
Sbjct: 216 RDCRNIGIDIPIIPGILPIQNLQTVRNLRKMNFA-VKVPNEILEVLKSGKEDLEAIQAFG 274
Query: 356 IHLGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEESKISR 496
I T+MC+++ A G ++ +HLYTLN+EK ++IL +L + +E ++++
Sbjct: 275 IQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILENLKISKEPELNK 322
[119][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 130 bits (327), Expect = 5e-29
Identities = 67/157 (42%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A Y+KDL K KVDAGAD +TQ FY+ D + FV
Sbjct: 136 FFIEVAAYPEMHPQ---------APSYEKDLENFKRKVDAGADSAITQYFYNADAYYHFV 186
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C ++G+T PIVPGIMPI NY R + C IP I LE D+ A++A+G
Sbjct: 187 DSCEKMGVTLPIVPGIMPITNYTQLARFSDACGADIPRWIRKRLEGFGDDSAAIRAFGED 246
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C+K++ G +H YT+N LAI +LGL
Sbjct: 247 VVTRLCEKLLEAGAPGLHFYTMNQAGPTLAIWNNLGL 283
[120][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 130 bits (327), Expect = 5e-29
Identities = 64/158 (40%), Positives = 94/158 (59%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A+ Y D+ YLK K DAGA+ +TQ F++ D + F+
Sbjct: 131 FHLEVAAYPEIHPQ---------AKSYSDDIRYLKGKFDAGANSAITQYFFNPDAYFYFI 181
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C +IGIT PI PGIMPI NYK R + C +IP + ALE D+EE+++A+G+
Sbjct: 182 EQCIKIGITQPIYPGIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEESLRAFGVD 241
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
L TE+C+ ++ + +H YT+N + I+ +LGLI
Sbjct: 242 LVTELCEVLLENEAPGLHFYTMNQTEPTAQIVRNLGLI 279
[121][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 130 bits (326), Expect = 6e-29
Identities = 62/157 (39%), Positives = 92/157 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A + DL K KVDAGAD +TQ FY+ + + +FV
Sbjct: 139 FHIEVACYPEVHPQ---------AASAESDLKNFKRKVDAGADSAITQYFYNPEAYFRFV 189
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+DC ++GI PIVPGIMPI N+ +R + C IP I LE D+ +A++ +G+
Sbjct: 190 DDCERLGIDIPIVPGIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDRKAIRTFGLE 249
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ TE+C++++ G +H YTLN ++ L + +LGL
Sbjct: 250 VVTELCRRLLEQGAPGLHFYTLNRAEACLEVWKALGL 286
[122][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 130 bits (326), Expect = 6e-29
Identities = 66/160 (41%), Positives = 94/160 (58%), Gaps = 2/160 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + G+P+ L P E ++ +LK K+D G + I TQ+F+D DIF+ +V
Sbjct: 106 FDIAVPGFPQHM--------LLPPEERDNEIRWLKEKIDEGVNFIFTQMFFDVDIFISWV 157
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GIT PIVPGIMPI + GFI+ T TKIP + ALEP+K ++E V+ G
Sbjct: 158 KAVRAAGITIPIVPGIMPIQTWNGFIKATNLASTKIPQFFLDALEPVKSDDEKVREVGTK 217
Query: 362 LGTEMCKKIM--AHGIKTVHLYTLNMEKSALAILMSLGLI 475
L +MC+KI+ GI+ +H YT+N+EK +L L L+
Sbjct: 218 LVADMCRKILDSGLGIRGLHFYTMNLEKGTRMLLEELNLV 257
[123][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 129 bits (324), Expect = 1e-28
Identities = 66/158 (41%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYP HPD Y+ DL +LK KVDAGAD I+TQLF++ F KF+
Sbjct: 143 FTICVAGYPAGHPD---------CASYEDDLKHLKEKVDAGADFIITQLFFENKTFFKFL 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
DCR IGI P++PGI+PI + ++P IM L+ IKDN+ A++ YG+
Sbjct: 194 QDCRDIGIKVPVIPGILPIQ----------LSRLEVPKSIMDDLQTIKDNDVAIRNYGVQ 243
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGL 472
MC++++ G + +H YTLN E + IL +LGL
Sbjct: 244 KAINMCRELLDSGLVPGLHFYTLNREVATREILTALGL 281
[124][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 129 bits (323), Expect = 1e-28
Identities = 68/155 (43%), Positives = 94/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVD GA IVTQ+FYD D F+++V
Sbjct: 146 FDIGVAGYPEGSDDNKNEDEL---------LDHLKEKVDMGATFIVTQMFYDADNFIRWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GIT PI+PGIMPI Y F+R + KIP E + ALEP+K+++ AV+ G
Sbjct: 197 KRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKT 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L MC+K++A+GI +H YT+N+ ++ +L L
Sbjct: 257 LVANMCRKLLANGIHHLHFYTMNLAQATRMLLEEL 291
[125][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 129 bits (323), Expect = 1e-28
Identities = 70/155 (45%), Positives = 92/155 (59%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVD GA IVTQ+FYD D F+++V
Sbjct: 141 FDIGVAGYPEGCDDNKDEDLL---------LDHLKEKVDMGASFIVTQMFYDADNFVRWV 191
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GIT PI+PGIMPI Y F+R + +IP E + LEPIK ++ AV+ G
Sbjct: 192 GRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWLQRLEPIKTDDAAVRIVGRQ 251
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L E+C+KI+A GI +H YT+N+ +S IL L
Sbjct: 252 LVVELCRKILAAGIHHLHFYTMNLAQSTALILEDL 286
[126][TOP]
>UniRef100_UPI00015B5A5C PREDICTED: hypothetical protein n=1 Tax=Nasonia vitripennis
RepID=UPI00015B5A5C
Length = 326
Score = 128 bits (321), Expect = 2e-28
Identities = 70/162 (43%), Positives = 100/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP +P++ + D+ YLK+KVDAGAD I+TQ F+++ +F+KFV
Sbjct: 166 FSICVAGYPEMHPH-------SPSK--ELDIFYLKAKVDAGADFILTQFFFESQLFIKFV 216
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
NDCR++GI+ PI+PGI P + K +M C T IP I L I+D++EAV+ +GI
Sbjct: 217 NDCREVGISVPIIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIEDDDEAVRKFGID 276
Query: 362 LGTEMCKKI--MAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
L ++ K+I AH H+YTLN SA+ + L E
Sbjct: 277 LSVKLIKEIRESAH-FCGYHVYTLNRSFSAIEVHRQLNTQHE 317
[127][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 128 bits (321), Expect = 2e-28
Identities = 65/159 (40%), Positives = 97/159 (61%), Gaps = 3/159 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AG+P+ HP+ EG +++ +LK+KVDAGA+ I TQ+FYDT IF +V
Sbjct: 146 FCVAVAGFPQGHPETPDTP-----EGRAQEMEWLKAKVDAGAEFIFTQMFYDTSIFFDWV 200
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GI PI+PGIMPI N++ F + +P+ AL P++ ++E V+ G
Sbjct: 201 KRVREAGINVPIIPGIMPIQNWEKFEKWVQRENIIVPSHFYEALNPVRGDDEKVRQVGTK 260
Query: 362 LGTEMCKKIMAH---GIKTVHLYTLNMEKSALAILMSLG 469
L +MCK I+ + GIK +H+YTLN+EK A +L LG
Sbjct: 261 LVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLLRELG 299
[128][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 128 bits (321), Expect = 2e-28
Identities = 66/160 (41%), Positives = 95/160 (59%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE G AP + + +LK KVD GA IVTQ+FYD + F+ +V
Sbjct: 147 FCIGVAGYPE---------GYAPGDDIDATIKHLKIKVDEGASFIVTQMFYDAENFVDWV 197
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GIT PI PGIMPI ++ F R + +IP + ALEP+KD++ V+ G
Sbjct: 198 KRVRAAGITIPIFPGIMPIQSWSTFNRRCEWSGVRIPQHFIDALEPLKDDDALVREKGSE 257
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
L EMC+K++ +GI +H YT+N+EK+ I+ +GL+ +
Sbjct: 258 LMAEMCQKLVDNGITRLHFYTMNLEKATKMIIEKMGLLNQ 297
[129][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 127 bits (320), Expect = 3e-28
Identities = 68/155 (43%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVD GA IVTQ+FYD D F+++V
Sbjct: 146 FDIGVAGYPEGCDDNKDEDSL---------LDHLKEKVDMGATFIVTQMFYDADNFIRWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R+ GIT PIVPGIMPI Y F+R K+P E MA LE +K+++ AV+ G
Sbjct: 197 GRVRERGITVPIVPGIMPIATYASFLRRANHMNCKVPEEWMAKLESVKNDDVAVRDIGKT 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L +MC+KI++ GI+ +H YT+N+ ++ +L L
Sbjct: 257 LVADMCRKILSAGIRHLHFYTMNLAQATRMVLEEL 291
[130][TOP]
>UniRef100_C5BTQ6 Methylenetetrahydrofolate reductase n=1 Tax=Teredinibacter turnerae
T7901 RepID=C5BTQ6_TERTT
Length = 282
Score = 127 bits (319), Expect = 4e-28
Identities = 62/159 (38%), Positives = 93/159 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP+ A+ Y +D+ YLK K DAGA+ +TQ FY+ D + FV
Sbjct: 133 FELCVAAYPEIHPE---------AKSYLQDIRYLKGKFDAGANCALTQYFYNPDSYFYFV 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+C + GI PI+PGIMPI NY+ R + C +IP I L DN+E+++A+
Sbjct: 184 EECAKEGIEGPIIPGIMPITNYQNIARFSDACGAEIPRWIRKRLNDFGDNQESLQAFTTD 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIE 478
L TE+C ++ +G +H YT+N + IL +LGL++
Sbjct: 244 LVTELCATLLENGAPGLHFYTMNQVEPTRTILTNLGLVD 282
[131][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 127 bits (319), Expect = 4e-28
Identities = 67/155 (43%), Positives = 92/155 (59%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVD GA IVTQ+FYD D F+++V
Sbjct: 146 FDIGVAGYPEGCDDNKNEDEL---------LDHLKEKVDMGATFIVTQMFYDADNFIRWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R G+ PI+PGIMPI Y F+R K KIP + ALEP+K+++ AV+ G
Sbjct: 197 KKVRDRGVNVPILPGIMPIATYASFLRRANHMKAKIPQAWLDALEPVKNDDVAVRDIGKS 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L EMC+K++A+GI +H YT+N+ ++ +L L
Sbjct: 257 LVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEEL 291
[132][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 126 bits (316), Expect = 9e-28
Identities = 61/157 (38%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP AE Y+ D+ YLK K DAGAD +TQ FY+ + + F+
Sbjct: 131 FHIEVAAYPEIHPQ---------AESYESDIQYLKGKFDAGADSAITQYFYNVEAYFYFL 181
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C +GI PI GIMPI NY R + C +IP I LE D++++++A+GI
Sbjct: 182 DRCAALGIDKPIYAGIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQDSIRAFGID 241
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C+ ++ G +H YT+N + L I +LGL
Sbjct: 242 VVTQLCQTLLESGAPGIHFYTMNQTQPTLQICRNLGL 278
[133][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 125 bits (315), Expect = 1e-27
Identities = 69/155 (44%), Positives = 91/155 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVDAGA IVTQ+FYD D F+++V
Sbjct: 146 FDIGVAGYPEGCDDNKDEDLL---------LDHLKEKVDAGATFIVTQMFYDADNFVRWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GI PI+PGIMPI Y F+R KIP E M LEP+K+++ AV+ G
Sbjct: 197 GKVRARGINVPIIPGIMPIATYASFLRRANHMNCKIPDEWMQRLEPVKNDDVAVRDIGKT 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
L E+C+KI+A GI +H YT+N+ ++ +L L
Sbjct: 257 LVAELCRKILAAGIHHLHFYTMNLAQATRMVLEEL 291
[134][TOP]
>UniRef100_A4A9E4 Methylenetetrahydrofolate reductase n=1 Tax=Congregibacter
litoralis KT71 RepID=A4A9E4_9GAMM
Length = 278
Score = 125 bits (313), Expect = 2e-27
Identities = 62/157 (39%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP AE Y+ D+ YLK K DAGAD +TQ FY+ + + F+
Sbjct: 131 FHIEVAAYPEIHPQ---------AESYESDIHYLKGKFDAGADSAITQYFYNVEAYFYFL 181
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C IGI PI GIMPI NY R + C +IP I LE D++E+++A+GI
Sbjct: 182 DRCAAIGIDKPIYAGIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQESIRAFGID 241
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C+ ++ +H YT+N + L I +LGL
Sbjct: 242 VVTQLCQTLLESDAPGIHFYTMNQAQPTLQICRNLGL 278
[135][TOP]
>UniRef100_Q3SFY6 Methylenetetrahydrofolate reductase n=1 Tax=Thiobacillus
denitrificans ATCC 25259 RepID=Q3SFY6_THIDA
Length = 276
Score = 124 bits (312), Expect = 3e-27
Identities = 61/157 (38%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A Y +DLA K KVDAGA+ +TQ F++ D + +FV
Sbjct: 129 FEIEVAAYPEVHPQ---------ARSYGEDLANFKRKVDAGANAAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R +G++ PIVPGIMPI NY R + C +IP + LE D+ +++A+G+
Sbjct: 180 DDARALGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLTSIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C +++A G +H YT+N + I LGL
Sbjct: 240 VVTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL 276
[136][TOP]
>UniRef100_B8KU68 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR51-B RepID=B8KU68_9GAMM
Length = 216
Score = 124 bits (311), Expect = 3e-27
Identities = 62/159 (38%), Positives = 90/159 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ Y+ D+ YLK K+DAGAD +TQ F++ D + F+
Sbjct: 65 FSIAVAAYPEIHPQ---------AKSYETDIFYLKQKLDAGADKAITQFFFNVDSYFYFL 115
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C+ GI PI PGIMPI N+ R G C +IP I + D++E+V+ +GI
Sbjct: 116 DRCQAAGIEQPIHPGIMPIVNFTNLERFAGSCGAEIPRWIRQRVAGFGDDQESVRKFGIE 175
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIE 478
+ T++C + G VH YT+N + L I +LGLI+
Sbjct: 176 VVTQICATLQESGAPGVHFYTMNQVEPTLTIAANLGLID 214
[137][TOP]
>UniRef100_C6P2D6 Methylenetetrahydrofolate reductase n=1 Tax=Sideroxydans
lithotrophicus ES-1 RepID=C6P2D6_9GAMM
Length = 280
Score = 123 bits (309), Expect = 6e-27
Identities = 59/156 (37%), Positives = 95/156 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ ++D+ K K++AGA+ +TQ FY+ D + +FV
Sbjct: 132 FHIEVAAYPEFHPQ---------AKSAREDMLNFKRKMNAGANSAITQYFYNADAYFRFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R++G+T PIVPGIMPI + R + C +IP + +E D+ E+V+A+G+
Sbjct: 183 EETRKLGVTAPIVPGIMPIGRFSQLARFSDNCGAEIPRWMRKTMEGYGDDSESVQAFGLD 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ T++C+K++A G ++H YTLN ++L IL LG
Sbjct: 243 VVTQLCEKLIAGGAPSLHFYTLNQANASLEILKRLG 278
[138][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 123 bits (309), Expect = 6e-27
Identities = 70/170 (41%), Positives = 99/170 (58%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ IVTQ+FYD D FL +V
Sbjct: 146 FDIGVGGYPEGADDNPDVDQL---------IDHLKEKVDAGSTFIVTQMFYDVDNFLNWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR GI IVPGIMPI+ Y F+R + + K +IP + + LEP+K ++ V+ G
Sbjct: 197 EKCRAKGINAAIVPGIMPISTYDAFMRRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTK 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L EMC+K++A G I +H YT+N+ ++ IL L L+ EE+ + + L
Sbjct: 257 LVAEMCRKLLASGHIHHLHFYTMNLAQATRLILEELRLLPSEEAPLQKPL 306
[139][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 123 bits (309), Expect = 6e-27
Identities = 66/160 (41%), Positives = 94/160 (58%), Gaps = 2/160 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AG+P+ + L P E Q ++ +LK KVDAG I TQ+FYD +F+ +V
Sbjct: 146 FDIAVAGFPQ-------HMALPPDERDQ-EIQWLKEKVDAGVAFIFTQMFYDVQLFIDWV 197
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GIT PIVPGI PI + GF R T K +P + ALEPIK+++E V+ G
Sbjct: 198 KAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKIVVPQSFLDALEPIKNDDEKVREVGTR 257
Query: 362 LGTEMCKKIMAH--GIKTVHLYTLNMEKSALAILMSLGLI 475
L +MC++I+ GI+ +H YT+N+EK +L L L+
Sbjct: 258 LVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLV 297
[140][TOP]
>UniRef100_B1ZNX1 Methylenetetrahydrofolate reductase n=1 Tax=Opitutus terrae PB90-1
RepID=B1ZNX1_OPITP
Length = 292
Score = 122 bits (307), Expect = 1e-26
Identities = 63/155 (40%), Positives = 86/155 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +AGYPE HP+ D DL LK KVDAGAD I TQLF+D ++ +FV
Sbjct: 145 FCLGVAGYPEKHPEAASLD---------VDLTNLKRKVDAGADFITTQLFFDNTVYYRFV 195
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
CR +GIT PIVPGIMP+ + R T C +P +++ LE +N + V+ GI
Sbjct: 196 EKCRAVGITVPIVPGIMPVLSLHQIQRFTAMCGATLPKQLITRLEVAAENTDVVETIGID 255
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ ++A+G HLY LN K+ALA+ L
Sbjct: 256 WALTQIRGLLANGAPGYHLYVLNRAKAALALTAGL 290
[141][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 122 bits (307), Expect = 1e-26
Identities = 63/157 (40%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I IA YPE HP A ++ DLA K AGAD +TQ F++ D + FV
Sbjct: 134 FHIEIAAYPEMHPQ---------ARNFEDDLANFVRKAKAGADSAITQYFFNADCYFYFV 184
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++G+ P+VPGIMPI NY R + C +IP + LE D+ ++++A+G
Sbjct: 185 ERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQAFGEQ 244
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ TEMC+K++A G +H YTLN + +LAI +LGL
Sbjct: 245 VITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGL 281
[142][TOP]
>UniRef100_C5V644 Methylenetetrahydrofolate reductase n=1 Tax=Gallionella ferruginea
ES-2 RepID=C5V644_9PROT
Length = 275
Score = 122 bits (306), Expect = 1e-26
Identities = 62/155 (40%), Positives = 89/155 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A+ + DL K K+DAGAD +TQ FY+ D + FV
Sbjct: 129 FHLEVAAYPEVHPQ---------AKSARDDLINFKRKIDAGADSAITQYFYNADSYFHFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++C++ GIT PIVPGIMPI Y R + C +IP + +E D+ E+V+A+G
Sbjct: 180 DECQKQGITAPIVPGIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T MC+K++A G +H YTLN +AI+ L
Sbjct: 240 IVTAMCEKLLAGGAPGLHFYTLNQAAPCMAIVERL 274
[143][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 122 bits (306), Expect = 1e-26
Identities = 69/170 (40%), Positives = 100/170 (58%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + GYPE D D L + +LK KVDAG+ IVTQ+FYD D FL +V
Sbjct: 146 FDIGVGGYPEGADDNPDVDQL---------IDHLKEKVDAGSSFIVTQMFYDVDNFLDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR GI I+PGIMPI+ Y F+R + + K +IP + + LEP+K ++ V+ G
Sbjct: 197 SKCRAKGIKAAIIPGIMPISTYDAFMRRSNWTKIRIPPDWLDKLEPVKADDAKVREIGTK 256
Query: 362 LGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLI--EESKISRSL 502
L EMC+K++A G I +H YT+N+ ++ IL L L+ EE+ + + L
Sbjct: 257 LVAEMCRKLLASGQIHHLHFYTMNLAQATRLILEELRLLPSEEAPLHKPL 306
[144][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 122 bits (306), Expect = 1e-26
Identities = 64/157 (40%), Positives = 92/157 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVDAGA IVTQ+FYD D F+ ++
Sbjct: 146 FDIGVAGYPEGCDDQDDEDLL---------LDHLKEKVDAGATFIVTQMFYDVDNFIDWL 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ G+T P++PGIMPIN Y F+R KIP + A+LE +K+++ AV+ G
Sbjct: 197 GKVKARGVTIPVIPGIMPINTYASFLRRCNHMGCKIPPKWSASLEAVKNDDSAVRNIGKD 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
L EMC++I+ G+ +H YT+N+ ++ +L L L
Sbjct: 257 LVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEELNL 293
[145][TOP]
>UniRef100_B0NXP2 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp. SS2/1
RepID=B0NXP2_9CLOT
Length = 295
Score = 122 bits (305), Expect = 2e-26
Identities = 61/155 (39%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F ++ A YPE H + A+G++KDL LK KVDAGA+ +VTQ+F+D D + + V
Sbjct: 142 FCLSGACYPETHQE---------ADGFKKDLEALKKKVDAGAEYLVTQIFFDNDYYYRLV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R+IGIT PI+ GIMPI N K IR T C IP ++ +E DN EA+K GI+
Sbjct: 193 REARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHYDNPEAMKEIGIN 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ ++ +G+ +H+YT+N ++A + S+
Sbjct: 253 YAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSI 287
[146][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 121 bits (304), Expect = 2e-26
Identities = 54/151 (35%), Positives = 83/151 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + ++D+ Y K KV+AGAD +TQ+F+D F F+
Sbjct: 142 FCIAVASYPEGHPE---------SPNLERDIYYFKQKVEAGADFSITQMFFDNSYFYDFL 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C + G+ PI+PGIMPI N+ + C IP +++ E DN E K GI
Sbjct: 193 DRCTKAGVNIPIIPGIMPITNFNQIRKFASLCGATIPEDVVKLFEKYADNPEETKKIGIE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
T+ C+ ++ +G+K +H YTLN + + I
Sbjct: 253 FATKQCEDLLKNGVKGLHFYTLNKSDATIKI 283
[147][TOP]
>UniRef100_B2AGG4 Methylenetetrahydrofolate reductase n=1 Tax=Cupriavidus taiwanensis
RepID=B2AGG4_CUPTR
Length = 276
Score = 121 bits (304), Expect = 2e-26
Identities = 60/157 (38%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DL KV AGAD +TQ FY+ D + +FV
Sbjct: 129 FNIEVAAYPEYHPQ---------AKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R +G+ PIVPGIMPI NY +R + C ++P + LE D+ E+++A+G+
Sbjct: 180 DDVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++A G+ +H YTLN + AI L L
Sbjct: 240 VVTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL 276
[148][TOP]
>UniRef100_A0Y9Q7 Methylenetetrahydrofolate reductase n=1 Tax=marine gamma
proteobacterium HTCC2143 RepID=A0Y9Q7_9GAMM
Length = 276
Score = 121 bits (304), Expect = 2e-26
Identities = 59/157 (37%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HPD A+G + D+ +LK K DAGA+ +TQ FY+ + + FV
Sbjct: 129 FQLEVAAYPEVHPD---------AKGPENDIEFLKRKFDAGANSAITQYFYNVEAYFYFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C++ GI PI PGIMPI NY R + C +IP I LE ++ E+V+ +GI
Sbjct: 180 EQCQKNGIDRPIYPGIMPITNYHNLARFSKSCGAEIPRWICQRLESFGNDSESVQEFGIE 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C++++A G +H YT+N + I +LG+
Sbjct: 240 VVTQLCQRLLAEGAPGIHFYTMNQVEPNRQIWKNLGI 276
[149][TOP]
>UniRef100_UPI0001BB45A7 5,10-methylenetetrahydrofolate reductase n=1 Tax=alpha
proteobacterium HIMB114 RepID=UPI0001BB45A7
Length = 298
Score = 121 bits (303), Expect = 3e-26
Identities = 64/155 (41%), Positives = 88/155 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++AGYPE HPD ++ + DL LK KVDAGAD I+TQ F+D +IFLKF
Sbjct: 133 FDISVAGYPEIHPD---------SKNKELDLDNLKRKVDAGADRIITQFFFDENIFLKFR 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D + GI ++PGIMPI NYK + C T +PA I E +DN + K G
Sbjct: 184 DDIAKQGIKIQLLPGIMPIQNYKRVKNFSNKCGTSVPAWIEKEFEGSEDNPDVQKMIGSS 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++ KK+ G+ H YTLN + + A+ L
Sbjct: 244 IATDLVKKLQKEGVNEFHFYTLNKYELSYAVCSRL 278
[150][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 121 bits (303), Expect = 3e-26
Identities = 56/151 (37%), Positives = 80/151 (52%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + ++++ Y K KV+AGAD +TQ+F+D F +F+
Sbjct: 142 FCIAVASYPEGHPE---------SSNLEREILYFKKKVEAGADFSITQMFFDNSYFYEFL 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C + GI PI+PGIMPI N+ + C IP E++ E DN E K GI
Sbjct: 193 EKCEKAGINIPIIPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYADNPEETKKIGIE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
T C ++ HG K +H YTLN + + I
Sbjct: 253 FATLQCIDLIKHGAKGLHFYTLNKSDATIKI 283
[151][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 121 bits (303), Expect = 3e-26
Identities = 61/164 (37%), Positives = 93/164 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A + DL KVDAGA+ +TQ F++ D + F+
Sbjct: 134 FNIEVAAYPEFHPQ---------ARTAEDDLKNFARKVDAGANSAITQYFFNADSYFYFI 184
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ ++G+T P+VPGIMPI N+ R + C +IP I LE D+ ++++ +G
Sbjct: 185 DRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRKFGEE 244
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKIS 493
+ TEMC K++A G +H YTLN + +L+I +LG+ E KI+
Sbjct: 245 VVTEMCAKLLAAGAPGLHFYTLNQAEPSLSIWKNLGIGEREKIA 288
[152][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 121 bits (303), Expect = 3e-26
Identities = 64/157 (40%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L L +LK KVDAGA IVTQ+FYD D F+ ++
Sbjct: 146 FDIGVAGYPEGCDDQDDEDLL---------LDHLKEKVDAGATFIVTQMFYDVDNFIDWL 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ G+ P++PGIMPIN Y F+R KIP + AALE +K+++ AV+ G
Sbjct: 197 GKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAALEEVKNDDAAVRNIGKD 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
L EMC++I+ G+ +H YT+N+ ++ +L L L
Sbjct: 257 LVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELSL 293
[153][TOP]
>UniRef100_B0T509 Methylenetetrahydrofolate reductase n=1 Tax=Caulobacter sp. K31
RepID=B0T509_CAUSK
Length = 320
Score = 120 bits (302), Expect = 4e-26
Identities = 58/159 (36%), Positives = 87/159 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + + YPE HP+ + + D+ LK+KVDAGA + ++Q F+DTD FL+FV
Sbjct: 157 FNVLVGVYPEKHPE---------SPSIEHDIEVLKAKVDAGATMAISQFFFDTDAFLRFV 207
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R GIT PIVPG+MP+ N+KG ++M+ C T +P + + + D+ + +
Sbjct: 208 DKVRAAGITIPIVPGVMPVTNFKGLVKMSKACGTAVPDWLTKLFDGLDDDADTRRLIACS 267
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIE 478
+ EMC K+ G H YTLN AI LG+ E
Sbjct: 268 VAAEMCAKLQEQGFSDFHFYTLNRADLVYAICRVLGVRE 306
[154][TOP]
>UniRef100_A1U549 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter aquaeolei
VT8 RepID=A1U549_MARAV
Length = 289
Score = 120 bits (302), Expect = 4e-26
Identities = 58/164 (35%), Positives = 94/164 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A ++DL KV AGA+ +TQ F++ D + F+
Sbjct: 134 FNLEVAAYPEFHPQ---------ARNAEEDLKNFARKVQAGANSAITQYFFNADSYFYFI 184
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ Q+G+T P+VPGIMPI N+ +R + C +IP I LE D+ ++++ +G
Sbjct: 185 DRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRKFGEE 244
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKIS 493
+ TEMC+K++ G +H YTLN + +L+I +LG+ + KI+
Sbjct: 245 VVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIA 288
[155][TOP]
>UniRef100_Q84CU6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=uncultured
bacterium RepID=Q84CU6_9BACT
Length = 253
Score = 120 bits (302), Expect = 4e-26
Identities = 61/166 (36%), Positives = 97/166 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP+ + KD+A K KV+AGA+ +TQ FY++D + +FV
Sbjct: 97 FHLEVAAYPEFHPEALSA---------AKDMANFKRKVEAGANSAITQYFYNSDAYFRFV 147
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C GI+ PIVPGIMPI NY R +G C +IP + LE D+ +++A GI
Sbjct: 148 DSCVADGISVPIVPGIMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYADDMPSLRALGID 207
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKISRS 499
+ +E+C+ ++A G+ ++H YTLN I+ ++GL + + R+
Sbjct: 208 VVSELCEVLLAGGVPSLHFYTLNQAGIISTIINNVGLEDATTQKRN 253
[156][TOP]
>UniRef100_Q4UQY4 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas campestris
pv. campestris RepID=Q4UQY4_XANC8
Length = 275
Score = 120 bits (301), Expect = 5e-26
Identities = 58/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP I D DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQAIDADS---------DLKYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAAQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAE 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C++++A G+ +H YTLN+ K +L LG
Sbjct: 239 VVAGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLG 274
[157][TOP]
>UniRef100_B0RV90 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. campestris str. B100 RepID=B0RV90_XANCB
Length = 285
Score = 120 bits (301), Expect = 5e-26
Identities = 58/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP I D DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 138 FRIEVGAYPETHPQAIDADS---------DLKYFKAKVDAGADAAITQYFYNADAYFHFR 188
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 189 DAAQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAE 248
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C++++A G+ +H YTLN+ K +L LG
Sbjct: 249 VVAGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLG 284
[158][TOP]
>UniRef100_Q1YUX2 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
HTCC2207 RepID=Q1YUX2_9GAMM
Length = 282
Score = 120 bits (301), Expect = 5e-26
Identities = 61/161 (37%), Positives = 90/161 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ AE Y KD+ +L K AGAD +TQ FY D +LKFV
Sbjct: 131 FNINVAAYPEIHPE---------AESYSKDVFWLGEKFKAGADRAITQYFYSADAYLKFV 181
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++C + GI PI+PGIMP+ NY IR + C IP + L+ DN + + +YGI
Sbjct: 182 DECAKGGINQPIIPGIMPLTNYANLIRFSDSCGADIPRWLRWQLKERSDNMDDLVSYGID 241
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEES 484
+ +E+ +K++ G +H YT+N + + +LG E +
Sbjct: 242 IVSELSQKLLDGGAPGLHFYTMNQWQVTGTLCRNLGFAENT 282
[159][TOP]
>UniRef100_B2ZZ98 Methylenetetrahydrofolate reductase n=1 Tax=Methylophilus
methylotrophus RepID=B2ZZ98_METME
Length = 275
Score = 120 bits (301), Expect = 5e-26
Identities = 57/143 (39%), Positives = 86/143 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP+ A QKDL K K+DAGAD +TQ FY+ D + +FV
Sbjct: 130 FHLEVAAYPEFHPE---------AGSAQKDLENFKRKIDAGADSAITQYFYNMDAYFRFV 180
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+++G+T PI+PGIMPI NY R + C +IP + LE D+ +++A+G+
Sbjct: 181 EAAQKMGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDLASLRAFGVD 240
Query: 362 LGTEMCKKIMAHGIKTVHLYTLN 430
+ T++C K++A G+ +H YTLN
Sbjct: 241 VVTDICAKLIASGVDKMHFYTLN 263
[160][TOP]
>UniRef100_A8V3W7 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8V3W7_9AQUI
Length = 230
Score = 120 bits (301), Expect = 5e-26
Identities = 57/151 (37%), Positives = 85/151 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + ++D+ Y K KV+AGAD +TQ+F+D F ++
Sbjct: 80 FSIGVAAYPEGHPE---------SPNLERDIYYFKKKVEAGADFAITQMFFDNKYFYDYL 130
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C++ GI PI+PGIMPI N+K + C IP ++ LE +D E V+ GI
Sbjct: 131 DLCQKEGINIPIIPGIMPITNFKQIRKFALMCGATIPEYLVKKLEKYQDIPEEVEKIGIE 190
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
E C+ ++ H +K +H YTLN K+ L I
Sbjct: 191 YAVEQCEDLLKHNVKGLHFYTLNKSKATLQI 221
[161][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 120 bits (301), Expect = 5e-26
Identities = 61/163 (37%), Positives = 92/163 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A ++DL KV+AGA+ +TQ F++ D +L F+
Sbjct: 163 FNLEVAAYPEFHPQ---------ARSAEEDLKNFARKVEAGANSAITQYFFNADSYLYFI 213
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ + GIT P+VPGIMPI N+ +R + C +IP I LE D+ E+++ +G
Sbjct: 214 DRLEKSGITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQFGEE 273
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKI 490
+ T MC+K++ G +H YTLN + +L I +LGL E KI
Sbjct: 274 VVTRMCEKLLKAGAPGLHFYTLNQVEPSLGIWKNLGLGEREKI 316
[162][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 120 bits (300), Expect = 7e-26
Identities = 55/151 (36%), Positives = 79/151 (52%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + ++++ Y K KV+ GAD +TQ+F+D F +F+
Sbjct: 142 FCIAVASYPEGHPE---------SPNLEREILYFKKKVEVGADFSITQMFFDNSYFYEFL 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C GI PI+PGIMPI N+ + C IP E++ E DN E K GI
Sbjct: 193 EKCEIAGINIPIIPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYADNPEETKKIGIE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
T C ++ HG+K +H YTLN + + I
Sbjct: 253 FATLQCMDLIKHGVKGLHFYTLNKSDATIKI 283
[163][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 119 bits (299), Expect = 8e-26
Identities = 59/157 (37%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A + DL KV AGAD +TQ F++ D + +FV
Sbjct: 129 FNIEVAAYPEYHPQ---------ARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R +G+ PIVPGIMPI NY +R + C ++P + LE D++EA++A+G+
Sbjct: 180 DDVRAMGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C +++ G+ +H YTLN + AI L L
Sbjct: 240 VVTDLCTRLLEAGVPGLHFYTLNAAGATKAIWQRLKL 276
[164][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 119 bits (299), Expect = 8e-26
Identities = 64/160 (40%), Positives = 93/160 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGY E D D L + +LK KVDAG IVTQ+FYD DIFL++V
Sbjct: 146 FDIGVAGYSEGSDDNDNVDEL---------IDHLKEKVDAGGTFIVTQMFYDVDIFLEWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R GI PI+PGIMPI+ + F+R + + IP ALEP+K+++ V+ G
Sbjct: 197 RKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDALEPVKNDDVEVREVGKM 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
L +MC+K++A GI +H YT+N+ ++ +L L L+ +
Sbjct: 257 LVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPD 296
[165][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 119 bits (299), Expect = 8e-26
Identities = 61/128 (47%), Positives = 84/128 (65%), Gaps = 1/128 (0%)
Frame = +2
Query: 86 KDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRM 265
++L +LK+KVDAGAD IVTQLFYD D FL+++ R GIT PI+PGIMPI Y F R+
Sbjct: 164 EELEHLKAKVDAGADFIVTQLFYDVDRFLQWLKKVRAKGITVPIIPGIMPIQTYATFARL 223
Query: 266 TGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAH-GIKTVHLYTLNMEKS 442
T C TK+P+ + A L PIK++++ VK YG+ + ++ GI+ H TLN+EKS
Sbjct: 224 TKLCGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIHRLRNEGGIQGFHFCTLNLEKS 283
Query: 443 ALAILMSL 466
+L L
Sbjct: 284 VQRVLEEL 291
[166][TOP]
>UniRef100_Q7UNJ7 Methylenetetrahydrofolate reductase n=1 Tax=Rhodopirellula baltica
RepID=Q7UNJ7_RHOBA
Length = 294
Score = 119 bits (298), Expect = 1e-25
Identities = 58/156 (37%), Positives = 90/156 (57%)
Frame = +2
Query: 5 GITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVN 184
GI +AGYPE H + + +Q DL LK KVDAGAD+++TQLFYD D F +F +
Sbjct: 146 GIAVAGYPETHQEAVD---------FQTDLTNLKRKVDAGADIVITQLFYDNDDFYRFRD 196
Query: 185 DCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHL 364
C ++GI PIVPGI+P+ N+K R+ CK IP + +A+ D+++ + G+
Sbjct: 197 ACEKVGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMTEADDDQDQFRV-GVEH 255
Query: 365 GTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ ++ +G+ +H Y LN ++A +L L L
Sbjct: 256 ARQQTIDLVNNGVPGIHYYVLNKSEAAAELLDGLSL 291
[167][TOP]
>UniRef100_Q1R0K0 Methylenetetrahydrofolate reductase n=1 Tax=Chromohalobacter
salexigens DSM 3043 RepID=Q1R0K0_CHRSD
Length = 282
Score = 119 bits (297), Expect = 1e-25
Identities = 61/155 (39%), Positives = 84/155 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPEAHP A Y+ DL K+ AGADL +TQ F+ D + FV
Sbjct: 133 FQIAVAAYPEAHPQ---------APSYEHDLQNFVRKMQAGADLAITQYFFSADAYFHFV 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R +G+ PIVPGIMPI NY R + C IP I LE D+ E+++A+G
Sbjct: 184 ERARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAFGSE 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T +C++++ G +H YTLN AL +L +L
Sbjct: 244 VVTRLCQRLLDGGAPGLHFYTLNQATPALRVLDNL 278
[168][TOP]
>UniRef100_A6C2T8 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces maris DSM
8797 RepID=A6C2T8_9PLAN
Length = 297
Score = 119 bits (297), Expect = 1e-25
Identities = 61/158 (38%), Positives = 88/158 (55%)
Frame = +2
Query: 5 GITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVN 184
GI +AGYPE HP+ A + DL LK KVDAGAD I TQLF++ + F +F
Sbjct: 142 GIGVAGYPECHPE---------ASDAEVDLTNLKRKVDAGADAIYTQLFFNNEHFYQFRE 192
Query: 185 DCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHL 364
C + GI PIVPGIMPI Y+ R+ C ++ PA+++ LE +D+ EA G+
Sbjct: 193 RCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQDDLEAQFEIGVEY 252
Query: 365 GTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIE 478
C++++ G+ +H Y LN ++ I +LG E
Sbjct: 253 AIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPE 290
[169][TOP]
>UniRef100_Q476T6 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha
JMP134 RepID=Q476T6_RALEJ
Length = 276
Score = 118 bits (296), Expect = 2e-25
Identities = 58/157 (36%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FQIEVAAYPEYHPQ---------AKSPRHDLENFVRKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R +G+ PIVPGIMPI NY +R + C +++P + LE D+ E+++A+G+
Sbjct: 180 DDARAMGVDVPIVPGIMPITNYSQLMRFSDMCGSEVPRWVAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++A G+ +H YTLN + AI L L
Sbjct: 240 VVTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL 276
[170][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 118 bits (296), Expect = 2e-25
Identities = 60/150 (40%), Positives = 82/150 (54%)
Frame = +2
Query: 17 AGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQ 196
A YPE H + D DL +LK+KVDAG D +VTQLF+D + FV R+
Sbjct: 146 ACYPEGHVETPSRDD---------DLRHLKAKVDAGLDFVVTQLFFDNAFYFDFVERARR 196
Query: 197 IGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM 376
GI PIVPGIMPI NY+ R T C +P + LE +KDN EA+ G+ T
Sbjct: 197 AGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKDNPEAMAQLGVAHATVQ 256
Query: 377 CKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
C ++++ G+ +H YTLN + I+ +L
Sbjct: 257 CMELLSRGVPGIHFYTLNKSPATRMIVSAL 286
[171][TOP]
>UniRef100_C4L7B5 Methylenetetrahydrofolate reductase n=1 Tax=Tolumonas auensis DSM
9187 RepID=C4L7B5_TOLAT
Length = 297
Score = 118 bits (296), Expect = 2e-25
Identities = 59/158 (37%), Positives = 90/158 (56%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++A YPE HP+ A+ Q DL +LK K+DAGA+ +TQ F+D + +L+F
Sbjct: 145 FDISVAAYPEVHPE---------AKSAQADLLHLKRKIDAGANRAITQFFFDVESYLRFR 195
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVK-AYGI 358
+ C IGI IVPGI+P++NYK ++ GF KIP + E I D+++ + G
Sbjct: 196 DRCAAIGIEAEIVPGILPVSNYKNLLKFAGFTNVKIPQWLHQRFEGIADDDQMTRNMVGA 255
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ +M + + G+K H YTLN + AI +LG+
Sbjct: 256 SIAIDMARVLSREGVKDFHFYTLNRSELTYAICHTLGV 293
[172][TOP]
>UniRef100_A1K2Z6 Methylenetetrahydrofolate reductase n=1 Tax=Azoarcus sp. BH72
RepID=A1K2Z6_AZOSB
Length = 277
Score = 118 bits (296), Expect = 2e-25
Identities = 61/157 (38%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP PA+ DLA K K+DAGAD +TQ FY+ D +L FV
Sbjct: 129 FRIEVAAYPEWHPQA-----KTPAD----DLAAFKRKMDAGADSAITQYFYNLDAYLHFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R++GI P+VPGIMPI ++ R + C +IP + E D+ +A++A+G+
Sbjct: 180 DAVRKLGIDKPVVPGIMPIGSFSKLARFSDACGAEIPRWMRRKFESYGDDADAIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ TE+C+K++A G+ +H Y++N I LGL
Sbjct: 240 VVTELCEKLLAAGVPGLHFYSMNQSALTTEICKRLGL 276
[173][TOP]
>UniRef100_C7RKF7 5,10-methylenetetrahydrofolate reductase n=1 Tax=Candidatus
Accumulibacter phosphatis clade IIA str. UW-1
RepID=C7RKF7_9PROT
Length = 279
Score = 118 bits (296), Expect = 2e-25
Identities = 59/157 (37%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A DL + K++AGA+ +TQ FY+ D + +F+
Sbjct: 131 FHIEVAAYPEYHPQ---------ARSPLDDLLAFRRKLEAGANSAITQYFYNFDAYAQFI 181
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR+IGI PIVPGIMPI++Y R + C +IP I LE D+ +++A+G+
Sbjct: 182 DQCRRIGIEVPIVPGIMPISSYSSLARFSDNCGAEIPRWIRKKLESYGDDSASIRAFGLD 241
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C+K++A G +H YTLN + LGL
Sbjct: 242 VVTQLCEKLLASGAPGLHFYTLNQASLTSTLWQRLGL 278
[174][TOP]
>UniRef100_C4KD22 Methylenetetrahydrofolate reductase n=1 Tax=Thauera sp. MZ1T
RepID=C4KD22_THASP
Length = 277
Score = 118 bits (296), Expect = 2e-25
Identities = 60/157 (38%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DLA K KV+AGAD +TQ FY+ D +L FV
Sbjct: 128 FRIEVAAYPEWHPQ---------AKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFV 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R++G+ PIVPGIMPI ++ R + C +IP + E D+ +A++A+G+
Sbjct: 179 DAVRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLD 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C+K++A G +H Y++NM I LGL
Sbjct: 239 VVTRLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGL 275
[175][TOP]
>UniRef100_Q3J7R3 Methylenetetrahydrofolate reductase n=2 Tax=Nitrosococcus oceani
RepID=Q3J7R3_NITOC
Length = 297
Score = 118 bits (296), Expect = 2e-25
Identities = 64/157 (40%), Positives = 86/157 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A Q DL K KV+AGAD +TQ FY+ D +L+FV
Sbjct: 138 FHIEVAAYPEVHPQ---------ARSAQADLINFKHKVEAGADSAITQYFYNVDAYLRFV 188
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C+ +GI PIVPGIMPINNY R + C +IP + LE D + A+ I
Sbjct: 189 ERCKSVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEDFPD-PATMSAFAID 247
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ +++C +++ G +H YTLN LAI +LGL
Sbjct: 248 VVSDLCYRLLEAGAPGLHFYTLNRADPTLAIWDNLGL 284
[176][TOP]
>UniRef100_B5WH86 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia sp. H160
RepID=B5WH86_9BURK
Length = 276
Score = 118 bits (296), Expect = 2e-25
Identities = 58/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ FY+ D + +FV
Sbjct: 129 FWIEVAGYPEYHPQ---------ARSPKHDLENFARKVKAGANSAITQYFYNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLE 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ + +H YTLN + AI LG+
Sbjct: 240 VVTNLCQRLVDAKVPGLHFYTLNTAAATKAICERLGV 276
[177][TOP]
>UniRef100_Q8Y389 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=Q8Y389_RALSO
Length = 276
Score = 118 bits (295), Expect = 2e-25
Identities = 60/157 (38%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAAYPEYHPQ---------ARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N +R + C +IP I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C +++A G +H YTLN + AI LGL
Sbjct: 240 VVTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL 276
[178][TOP]
>UniRef100_C1DIB8 Methylenetetrahydrofolate reductase n=1 Tax=Azotobacter vinelandii
DJ RepID=C1DIB8_AZOVD
Length = 281
Score = 118 bits (295), Expect = 2e-25
Identities = 61/157 (38%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A + DLA +K+ AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNLEDDLARFAAKMKAGADSAITQYFFNADSYFHFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++G+ PIVPGIMPI NY R + C ++P + LE D+ E+++A+G
Sbjct: 183 ERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFGEQ 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T MC+K++ G +H YTLN + +LAI +LGL
Sbjct: 243 VVTAMCEKLLEGGAPGLHFYTLNQAEPSLAIWNNLGL 279
[179][TOP]
>UniRef100_B6J3R7 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
CbuG_Q212 RepID=B6J3R7_COXB2
Length = 290
Score = 118 bits (295), Expect = 2e-25
Identities = 57/155 (36%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ Q+ L + K+ AGA+ +TQ FY+ D + FV
Sbjct: 132 FHIEVAAYPEFHPET---------RTVQEALKNFQQKIAAGANGAITQYFYNRDAYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR +GI PIVPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+
Sbjct: 183 DACRNVGIKAPIVPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++C+ ++A+G+ +H YTLN + I+ +L
Sbjct: 243 VVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENL 277
[180][TOP]
>UniRef100_A9N9C8 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=A9N9C8_COXBR
Length = 290
Score = 118 bits (295), Expect = 2e-25
Identities = 57/155 (36%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ Q+ L + K+ AGA+ +TQ FY+ D + FV
Sbjct: 132 FHIEVAAYPEFHPET---------RTVQEALKNFQQKIAAGANGAITQYFYNRDAYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR +GI PIVPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+
Sbjct: 183 DACRNVGIEAPIVPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++C+ ++A+G+ +H YTLN + I+ +L
Sbjct: 243 VVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENL 277
[181][TOP]
>UniRef100_B5S7H8 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=B5S7H8_RALSO
Length = 276
Score = 118 bits (295), Expect = 2e-25
Identities = 60/157 (38%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAAYPEYHPQ---------ARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N +R + C +IP I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C +++A G +H YTLN + AI LGL
Sbjct: 240 VVTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL 276
[182][TOP]
>UniRef100_B6J6H7 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=B6J6H7_COXB1
Length = 290
Score = 118 bits (295), Expect = 2e-25
Identities = 57/155 (36%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ Q+ L + K+ AGA+ +TQ FY+ D + FV
Sbjct: 132 FHIKVAAYPEFHPET---------RTVQEALKNFQQKIAAGANGAITQYFYNRDAYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR +GI PIVPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+
Sbjct: 183 DACRNVGIEAPIVPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++C+ ++A+G+ +H YTLN + I+ +L
Sbjct: 243 VVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENL 277
[183][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 118 bits (295), Expect = 2e-25
Identities = 67/162 (41%), Positives = 92/162 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE D D L + +LK KVDAG I+TQ+FYD D FL +V
Sbjct: 146 FDIGVAGYPEGCDDQDDPDLL---------MQHLKEKVDAGGTFIITQMFYDVDNFLAWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
N CR GIT PI+PGIMPI+ IP + + ALEP+K+++ AV+ G
Sbjct: 197 NKCRDNGITVPIIPGIMPIHT--------------IPPDWLEALEPVKNDDVAVRNLGKS 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESK 487
L MC+K++A GI +H YT+N++++ +L L LI K
Sbjct: 243 LVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGELELIPSHK 284
[184][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 117 bits (294), Expect = 3e-25
Identities = 53/151 (35%), Positives = 88/151 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + +KD+ Y K KV+AGA+ +TQ+F+D F +++
Sbjct: 143 FSIGVAAYPEGHPE---------SPSLEKDIYYFKKKVEAGAEFAITQMFFDNSYFYRYM 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ + GI P++PGIMPI N++ + C IP +++ LE ++++ E V GI
Sbjct: 194 DLLSKEGINIPVIPGIMPITNFRQIEKFAVMCGATIPKDLVEKLEKVENSPEEVAKIGID 253
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
TE C+ ++ +G+K +H YTLN K+ + I
Sbjct: 254 YATEQCEDLLKNGVKGLHFYTLNKSKATVEI 284
[185][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 117 bits (294), Expect = 3e-25
Identities = 60/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AG+PE H +A EG D +LK K+D GAD +VTQLFY+ + +F
Sbjct: 152 FSIGTAGFPEGH--------IACKEGKHVDWEHLKKKIDCGADFVVTQLFYNNADYFEFR 203
Query: 182 NDC-RQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGI 358
+ +++G + PI PGI+PI + R++ C K+P+ +++ LE + DN+EA AYGI
Sbjct: 204 DHLTKKLGASVPIFPGILPILSAGQIKRISALCGAKLPSRLVSCLEKLADNDEAAAAYGI 263
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
TE C +++ G +H+YTLN S + +L +L L
Sbjct: 264 DYATEQCAELLREGAPGLHMYTLNKAPSTIQVLKNLAL 301
[186][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 117 bits (294), Expect = 3e-25
Identities = 60/157 (38%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAAYPEYHPQ---------ARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N +R + C +IP I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C +++A G +H YTLN + AI LGL
Sbjct: 240 VVTALCDRLLAGGAPGLHFYTLNAAGATRAIWQRLGL 276
[187][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 117 bits (294), Expect = 3e-25
Identities = 63/160 (39%), Positives = 93/160 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGY E D D L + +LK KVDAGA IVTQ+FYDTDIF+ +V
Sbjct: 146 FDIGVAGYSEGSDDNDNVDEL---------IDHLKEKVDAGATFIVTQMFYDTDIFIDWV 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
N R G+ I+PGIMPI+ + F+R + + IP ALEPIK+++ V+ G
Sbjct: 197 NKVRAKGVDAVIIPGIMPIHTHASFLRRAQWTRCNIPQHWTDALEPIKNDDVEVREVGKG 256
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
L +MC++++ GI +H YT+N+ ++ +L L L+ +
Sbjct: 257 LVADMCRRLIEAGITHLHFYTMNLAQATRMVLEELDLLPD 296
[188][TOP]
>UniRef100_Q0KF23 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha H16
RepID=Q0KF23_RALEH
Length = 276
Score = 117 bits (293), Expect = 4e-25
Identities = 59/157 (37%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DL KV AGA+ +TQ FY+ D + +FV
Sbjct: 129 FNIEVAAYPEYHPQ---------AKSPRHDLENFVRKVKAGANSAITQYFYNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R G+ PIVPGIMPI NY +R + C ++P + LE D+ E+++A+G+
Sbjct: 180 DDVRATGLEVPIVPGIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++A G+ +H YTLN + AI L L
Sbjct: 240 VVTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL 276
[189][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 117 bits (293), Expect = 4e-25
Identities = 60/157 (38%), Positives = 87/157 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP + + DL KV AGAD +TQ F++ D + +FV
Sbjct: 129 FHIEVAAYPEYHPQ---------SRSARHDLENFARKVKAGADSAITQYFFNADAYFQFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N +R + C ++P I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T MC +++ G +H YTLN S AI LGL
Sbjct: 240 VVTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL 276
[190][TOP]
>UniRef100_B4SAJ8 Methylenetetrahydrofolate reductase n=1 Tax=Pelodictyon
phaeoclathratiforme BU-1 RepID=B4SAJ8_PELPB
Length = 289
Score = 117 bits (293), Expect = 4e-25
Identities = 64/156 (41%), Positives = 89/156 (57%), Gaps = 1/156 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AG+PE HP+ K++ YLK KVDAGAD IVTQLF+D + FV
Sbjct: 142 FGIGVAGFPEGHPETPNR---------MKEIEYLKEKVDAGADYIVTQLFFDNHDYFDFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGI 358
C GIT PI+PGIMPI KG IRM+ ++PA ++ + N++ V + GI
Sbjct: 193 ERCALGGITVPIIPGIMPITTRKGMIRMSELALGARVPAALLKKVLTAA-NDDEVASVGI 251
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
T ++++ H IK +H YTLNM + L I ++
Sbjct: 252 EWATNQVQELIDHHIKGIHFYTLNMADATLKIFNNI 287
[191][TOP]
>UniRef100_B2SPM2 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae pv.
oryzae PXO99A RepID=B2SPM2_XANOP
Length = 275
Score = 117 bits (293), Expect = 4e-25
Identities = 59/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP D L+ DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQA--TDALS-------DLRYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAVQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGAD 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C+++MA G +H YTLN+ K +L LG
Sbjct: 239 VVAALCERLMAGGAPALHFYTLNLAKPTTQVLQLLG 274
[192][TOP]
>UniRef100_C1ZF18 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces
limnophilus DSM 3776 RepID=C1ZF18_PLALI
Length = 310
Score = 117 bits (293), Expect = 4e-25
Identities = 58/158 (36%), Positives = 87/158 (55%), Gaps = 2/158 (1%)
Frame = +2
Query: 5 GITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVN 184
GI +AGYPE HP+ + + D+A+LK K+ G + TQLFYD + F ++
Sbjct: 154 GIGVAGYPEKHPEAVS---------LETDIAFLKEKITVGGHAVFTQLFYDNETFYRYWE 204
Query: 185 DCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEP--IKDNEEAVKAYGI 358
C + GI PI+PG+MPI Y R+ TK+PAE++ LE ++D++ A GI
Sbjct: 205 MCLKQGIDAPIIPGVMPITEYSRVKRIVEISGTKVPAELLEQLEAAHLRDDKAAQLEIGI 264
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ C+ ++ HG+ +H Y LN + IL SLGL
Sbjct: 265 EYSVQQCQDLIDHGVPGLHFYVLNKAHATSQILQSLGL 302
[193][TOP]
>UniRef100_UPI0001744B57 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B57
Length = 300
Score = 117 bits (292), Expect = 6e-25
Identities = 67/164 (40%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI IAG+PE HP P + D YLK+KVDAGAD I TQLF+D FL F
Sbjct: 146 FGIGIAGFPEGHP-------ATPNRLLEMD--YLKAKVDAGADYICTQLFFDNRDFLDFR 196
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCK-TKIPAEIMAALEPIKDNEEAVKAYGI 358
+ C GI PI+ GIMPI++ G RM + PA+++ A+ +E AV+ GI
Sbjct: 197 DRCHLAGINVPIIAGIMPISSASGMKRMAELAAGARFPAKLLKAISRCNGDEAAVERVGI 256
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEESKI 490
H TE C ++ H H YTLN ++ I SLGL + +
Sbjct: 257 HYATEQCADLLDHQADGFHFYTLNKSRATREIYASLGLKDSRSV 300
[194][TOP]
>UniRef100_UPI0001695145 5,10-methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae
pv. oryzicola BLS256 RepID=UPI0001695145
Length = 275
Score = 117 bits (292), Expect = 6e-25
Identities = 59/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP D L+ DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQA--TDALS-------DLRYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAVQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAD 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C+++MA G +H YTLN+ K +L LG
Sbjct: 239 VVAALCERLMAGGAPALHFYTLNLAKPTTQVLQLLG 274
[195][TOP]
>UniRef100_Q0C0E3 Methylenetetrahydrofolate reductase n=1 Tax=Hyphomonas neptunium
ATCC 15444 RepID=Q0C0E3_HYPNA
Length = 304
Score = 117 bits (292), Expect = 6e-25
Identities = 59/161 (36%), Positives = 93/161 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I+++ YPE HP+ +G D ++A+LK+K DAGAD +TQ F++ D++L F+
Sbjct: 149 FEISVSCYPELHPENLGWDA---------EIAFLKAKQDAGADRAITQFFFEPDVYLAFL 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R G+T PIVPGIM N+ G R+ G C + IPA + + + ++EE +
Sbjct: 200 EKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGSSIPAWLHTLYDGLDEDEETRDLVTAN 259
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEES 484
+ ++C+K+ A G++ H YTLN AL+ LGL +S
Sbjct: 260 VAADLCRKLQAEGVEDFHFYTLNRAGLALSTCRLLGLNPQS 300
[196][TOP]
>UniRef100_C5T5U6 Methylenetetrahydrofolate reductase n=1 Tax=Acidovorax delafieldii
2AN RepID=C5T5U6_ACIDE
Length = 283
Score = 117 bits (292), Expect = 6e-25
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DL +KV AGAD +TQ FY++D + +FV
Sbjct: 136 FHIEVAAYPEVHPQ---------AKSPEADLQAYVTKVRAGADSAITQYFYNSDAYFRFV 186
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
D RQ+G P+VPGIMPI++ +R + C +IP I L+ D+ ++KA+G+
Sbjct: 187 EDARQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLD 246
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C ++ + G+ +H YT+N + L I LG+
Sbjct: 247 VVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI 283
[197][TOP]
>UniRef100_Q21NJ7 Methylenetetrahydrofolate reductase n=1 Tax=Saccharophagus
degradans 2-40 RepID=Q21NJ7_SACD2
Length = 297
Score = 116 bits (291), Expect = 7e-25
Identities = 58/157 (36%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP+ A Y D+ YLK K DAGA+ +TQ F++ D + F+
Sbjct: 132 FHLEVAAYPEIHPE---------ATSYLDDVRYLKGKFDAGANSAITQYFFNPDAYFYFM 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C++ GI PI PGIMPI NY+ R + C IP + +E DN+EA+ ++GI
Sbjct: 183 DQCQKEGIDQPIYPGIMPILNYRNLARFSDSCGADIPRWMRKRMESFGDNQEALISFGID 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+E+C ++ G +H YT+N + I+ +LGL
Sbjct: 243 WISELCDTLLDAGAPGLHFYTMNQTEPTATIIKNLGL 279
[198][TOP]
>UniRef100_B1Y645 Methylenetetrahydrofolate reductase n=1 Tax=Leptothrix cholodnii
SP-6 RepID=B1Y645_LEPCP
Length = 279
Score = 116 bits (291), Expect = 7e-25
Identities = 59/157 (37%), Positives = 87/157 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A Q DL +KV AGAD +TQ F++ D + +FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARSPQADLQAYAAKVQAGADSAITQFFFNADAYWRFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D + +G P+VPGIMPI N G IR +IP I L+ D+ ++KA+G+
Sbjct: 183 DDAQALGARIPVVPGIMPITNSSGIIRFADGSGAEIPRWIRLRLQSYGDDSASIKAFGLD 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C+++ A G+ +H YT+N + L I LGL
Sbjct: 243 VVTDLCERLRAGGVPALHFYTMNSSAAVLQICERLGL 279
[199][TOP]
>UniRef100_A9KD99 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
Dugway 5J108-111 RepID=A9KD99_COXBN
Length = 290
Score = 116 bits (291), Expect = 7e-25
Identities = 56/155 (36%), Positives = 93/155 (60%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ Q+ L + K+ AGA+ +TQ FY+ D + FV
Sbjct: 132 FHIEVAAYPEFHPET---------RTVQEALKNFQQKIAAGANGAITQYFYNRDAYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ CR +GI PIVPGIMPI+++ ++ + C T+IP + LE K+++ ++KAYG+
Sbjct: 183 DACRNVGIEAPIVPGIMPISDFDKLVQFSKTCATEIPRWLYKRLESYKNDKASLKAYGVE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++C+ ++A+G+ +H YTLN + I+ +L
Sbjct: 243 VVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENL 277
[200][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 116 bits (291), Expect = 7e-25
Identities = 57/157 (36%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ D+A K AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNFESDIANFVRKAKAGADSAITQYFFNADSYFYFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
R++G+ P+VPGIMPI NY R + C +IP + LE D+ ++++A+G
Sbjct: 183 ERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFGEQ 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ TEMC++++ G +H Y++N+ +LAI +LGL
Sbjct: 243 VITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLGL 279
[201][TOP]
>UniRef100_Q2Y5Z3 Methylenetetrahydrofolate reductase n=1 Tax=Nitrosospira
multiformis ATCC 25196 RepID=Q2Y5Z3_NITMU
Length = 281
Score = 116 bits (290), Expect = 9e-25
Identities = 58/157 (36%), Positives = 85/157 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A Q+DL K K++AGAD +TQ FY+ D + FV
Sbjct: 134 FHIDVASYPEYHPQ---------ARTAQEDLRNFKRKIEAGADSAITQYFYNADAYFDFV 184
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C +GI P+VPGIMPIN + R + C +IP I LE D+ +++A+G+
Sbjct: 185 DSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDTASIRAFGLD 244
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C +++ G +H YTLN + LGL
Sbjct: 245 VVTDLCARLLNAGAPGLHFYTLNSAGLTTTVWQRLGL 281
[202][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 116 bits (290), Expect = 9e-25
Identities = 59/157 (37%), Positives = 87/157 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP + + DL KV +GAD +TQ F++ D + +FV
Sbjct: 129 FHIEVAAYPEYHPQ---------SRSARHDLENFARKVKSGADSAITQYFFNADAYFQFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N +R + C ++P I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T MC +++ G +H YTLN S AI LGL
Sbjct: 240 VVTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL 276
[203][TOP]
>UniRef100_B0UTC8 Methylenetetrahydrofolate reductase n=1 Tax=Haemophilus somnus 2336
RepID=B0UTC8_HAES2
Length = 294
Score = 116 bits (290), Expect = 9e-25
Identities = 58/157 (36%), Positives = 87/157 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++A YPE HP+ A+ Q DL LK K+DAGA+L++TQ F+D D +L+F
Sbjct: 143 FDISVAAYPEVHPE---------AKSAQADLINLKRKIDAGANLVITQFFFDVDSYLRFR 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C IGI IVPGI+P+ N+K +M KIP+ + E + D++
Sbjct: 194 DRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPSWMAKMYEGLDDDQTTRNLVAAS 253
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ +M K + G+K H YTLN + + AI +LG+
Sbjct: 254 IAMDMVKVLSCEGVKDFHFYTLNRSELSYAICHTLGV 290
[204][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 116 bits (290), Expect = 9e-25
Identities = 62/159 (38%), Positives = 89/159 (55%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I AG+PE H +A G D YL K+ AGAD +VTQLF+D + +F
Sbjct: 145 FSIGTAGFPEGH--------IAQHAGKLVDWQYLADKIAAGADFVVTQLFFDNADYYEFY 196
Query: 182 NDC-RQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGI 358
+ ++G+T PIVPGIMPI R C K+PA+ + L+ + ++EAV AYGI
Sbjct: 197 DHLVGKLGVTVPIVPGIMPILTAGQTRRFVSLCGAKLPAQFLRRLDELDGDDEAVAAYGI 256
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLI 475
TE C ++ G+ +H YTLN +S + I+ +LGL+
Sbjct: 257 EYATEQCASLLEFGVPGLHFYTLNKARSTVQIVRNLGLL 295
[205][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 116 bits (290), Expect = 9e-25
Identities = 51/155 (32%), Positives = 86/155 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP+ + + ++ + K KV+AGAD +TQ+F++ + +FV
Sbjct: 142 FSVGVASYPEGHPE---------SPNMEWEIRFFKEKVEAGADFSITQMFFENRYYYEFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C + GI PI+PGIMPI N+K + C IP ++ +EP++D E V G+
Sbjct: 193 ELCLKAGIEIPIIPGIMPITNFKQIKKFASMCGATIPQSLIEKMEPVEDKPEEVAKIGVE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ C+ ++ +G+ +H YTLN K+ L I ++
Sbjct: 253 FAVKQCEDLLRNGVPGLHFYTLNRSKATLNIYSAI 287
[206][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 116 bits (290), Expect = 9e-25
Identities = 55/151 (36%), Positives = 80/151 (52%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + + ++ Y K KV+AGAD +TQ+F+ D + +FV
Sbjct: 142 FSIGVASYPEGHPE---------SPNLEWEVKYFKEKVEAGADFSITQMFFVNDYYYRFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C+ GI I+PGIMPI N+K + C IP ++ LE ++D E VK GI
Sbjct: 193 EMCKNAGIDISIIPGIMPITNFKQIRKFASLCGATIPQSLIEKLEKVEDKPEEVKKIGIE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
C ++ HG+ +H YTLN + L I
Sbjct: 253 FAINQCLDLIEHGVPGLHFYTLNKSDATLKI 283
[207][TOP]
>UniRef100_Q8KCP5 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobaculum tepidum
RepID=Q8KCP5_CHLTE
Length = 290
Score = 115 bits (289), Expect = 1e-24
Identities = 62/155 (40%), Positives = 91/155 (58%), Gaps = 1/155 (0%)
Frame = +2
Query: 5 GITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVN 184
GI +AG+PE HP+ K+L +LK KVDAGAD IVTQLF+D + +V
Sbjct: 143 GIGVAGFPEGHPETPNR---------MKELEFLKEKVDAGADYIVTQLFFDNHDYFDYVE 193
Query: 185 DCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C GIT PI+PGIMPI + KG IRM ++IP++++ + D++E V G+
Sbjct: 194 RCELAGITVPIIPGIMPIMSKKGMIRMCELALGSRIPSKLLRKVLEAADDKE-VAEIGVE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
T ++++ H +K VH YTLN+ ++ L I +L
Sbjct: 253 WATNQVQELLDHKVKGVHFYTLNLSEATLKIFRNL 287
[208][TOP]
>UniRef100_Q2NZD1 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas oryzae pv.
oryzae RepID=Q2NZD1_XANOM
Length = 275
Score = 115 bits (289), Expect = 1e-24
Identities = 58/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP D L+ DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQA--TDALS-------DLRYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAVQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGAD 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C++++A G +H YTLN+ K +L LG
Sbjct: 239 VVAALCERLIAGGAPALHFYTLNLAKPTTQVLQLLG 274
[209][TOP]
>UniRef100_B3QMQ3 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobaculum parvum
NCIB 8327 RepID=B3QMQ3_CHLP8
Length = 290
Score = 115 bits (289), Expect = 1e-24
Identities = 61/155 (39%), Positives = 90/155 (58%), Gaps = 1/155 (0%)
Frame = +2
Query: 5 GITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVN 184
GI +AG+PE HP+ K+L YLK K+DAGAD IVTQLF+D + +V
Sbjct: 143 GIGVAGFPEGHPETPNR---------MKELEYLKEKIDAGADYIVTQLFFDNRDYFDYVE 193
Query: 185 DCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C GIT PI+PGIMPI KG IRM ++IP++++ + D++E V G+
Sbjct: 194 RCELAGITVPIIPGIMPIMTKKGMIRMGELALGSRIPSKLLRKVLEASDDKE-VAEIGVE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
T ++++ H +K +H YTLN+ ++ L I +L
Sbjct: 253 WATNQVQELLDHKVKGIHFYTLNLSEATLKIFRNL 287
[210][TOP]
>UniRef100_Q6J6A1 Methylenetetrahydrofolate reductase n=1 Tax=Collimonas fungivorans
RepID=Q6J6A1_9BURK
Length = 284
Score = 115 bits (289), Expect = 1e-24
Identities = 56/157 (35%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ Q D+ SKV AGA+ +TQ FY+ D + +FV
Sbjct: 137 FHIEVAAYPEMHPQ---------AKSPQDDVQRFVSKVKAGANGAITQYFYNADAYFRFV 187
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++ +++G P++ GIMPI NY +R + C T+IP I L D+ ++++A+G+
Sbjct: 188 DEAQKLGAAVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDSIRAFGLD 247
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C++++A G +H YTLN + +AI L L
Sbjct: 248 VVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL 284
[211][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 115 bits (289), Expect = 1e-24
Identities = 58/157 (36%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A ++ DL K KV+AGAD +TQ F++ D + +V
Sbjct: 130 FHLEVAAYPEMHPQ---------APNFEADLENFKRKVEAGADSAITQYFFNPDSYFYYV 180
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C ++GI PIVPGIMPI NY R + C +IP I LE D+ E+++ +G
Sbjct: 181 DRCMEMGIEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVESIQKFGEE 240
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC+ ++ + + +H YTLN + I +LGL
Sbjct: 241 VVTQMCEDLVENDVPGLHFYTLNQADPCINIWKNLGL 277
[212][TOP]
>UniRef100_A3VNZ5 Methylenetetrahydrofolate reductase n=1 Tax=Parvularcula
bermudensis HTCC2503 RepID=A3VNZ5_9PROT
Length = 290
Score = 115 bits (289), Expect = 1e-24
Identities = 55/157 (35%), Positives = 86/157 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F +T+ YPE HP+ + D+ +LK KVDAGA +TQ F+D +++ ++V
Sbjct: 133 FEVTVGCYPETHPESANREA---------DIDWLKQKVDAGATRAITQFFFDNNVYERYV 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R+ GI PIVPGIMP+ +YK RM G C IP I E + ++ E + +
Sbjct: 184 DDVRRAGIDIPIVPGIMPVGSYKALSRMAGLCGATIPPTIKDCFEDLDNDPETRRLAAVT 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ C+ ++ G++ +H YTLN A A+ LG+
Sbjct: 244 TVADQCRDLVRRGVEDLHFYTLNRADIAYAVCHLLGI 280
[213][TOP]
>UniRef100_UPI0001AF5FB3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. oryzae str. 1_6 RepID=UPI0001AF5FB3
Length = 281
Score = 115 bits (288), Expect = 2e-24
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ DL + +K +AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNFEDDLKHFVNKANAGADSAITQYFFNADSYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++G++ PIVPGIMPI NY R + C +IP I LE D+ ++++A+G
Sbjct: 183 ERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC++++ G +H YTLN + +LA+ +L L
Sbjct: 243 VITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQL 279
[214][TOP]
>UniRef100_UPI0001873BC3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. tomato T1 RepID=UPI0001873BC3
Length = 281
Score = 115 bits (288), Expect = 2e-24
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ DL + +K +AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNFEDDLKHFVTKANAGADSAITQYFFNADSYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++G++ PIVPGIMPI NY R + C +IP I LE D+ ++++A+G
Sbjct: 183 ERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGED 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC++++ G +H YTLN + +LA+ +L L
Sbjct: 243 VITQMCERLLEDGAPGLHFYTLNQAEPSLAVWNNLQL 279
[215][TOP]
>UniRef100_UPI00016A554F 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
ubonensis Bu RepID=UPI00016A554F
Length = 276
Score = 115 bits (288), Expect = 2e-24
Identities = 56/157 (35%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP + + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FRIEVAGYPEYHPQ---------SRSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P I LE D+ +A++A+G
Sbjct: 180 DDARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN + I LG+
Sbjct: 240 VVTGLCQRLLDAGVPGLHFYTLNSAAATKTICERLGV 276
[216][TOP]
>UniRef100_Q8PP97 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas axonopodis
pv. citri RepID=Q8PP97_XANAC
Length = 275
Score = 115 bits (288), Expect = 2e-24
Identities = 58/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP D L+ DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQAA--DALS-------DLRYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAE 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C++++A G +H YTLN+ K +L LG
Sbjct: 239 VVAALCERLIAGGAPALHFYTLNLAKPTTQVLQLLG 274
[217][TOP]
>UniRef100_Q4ZZ93 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. syringae B728a RepID=Q4ZZ93_PSEU2
Length = 281
Score = 115 bits (288), Expect = 2e-24
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ DL + +K +AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNFEDDLKHFVNKANAGADSAITQYFFNADSYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++G++ PIVPGIMPI NY R + C +IP I LE D+ ++++A+G
Sbjct: 183 ERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC++++ G +H YTLN + +LA+ +L L
Sbjct: 243 VITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQL 279
[218][TOP]
>UniRef100_Q48PB6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. phaseolicola 1448A RepID=Q48PB6_PSE14
Length = 291
Score = 115 bits (288), Expect = 2e-24
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ DL + +K +AGAD +TQ F++ D + FV
Sbjct: 142 FHIEVAAYPEMHPQ---------ARNFEDDLKHFVNKANAGADSAITQYFFNADSYFNFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++G++ PIVPGIMPI NY R + C +IP I LE D+ ++++A+G
Sbjct: 193 ERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC++++ G +H YTLN + +LA+ +L L
Sbjct: 253 VITQMCERLLQGGTPGLHFYTLNQAEPSLAVWNNLQL 289
[219][TOP]
>UniRef100_Q3BXE0 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. vesicatoria str. 85-10 RepID=Q3BXE0_XANC5
Length = 275
Score = 115 bits (288), Expect = 2e-24
Identities = 58/156 (37%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP D L+ DL Y K+KVDAGAD +TQ FY+ D + F
Sbjct: 128 FRIEVGAYPETHPQAA--DALS-------DLRYFKAKVDAGADAAITQYFYNADAYFHFR 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+ PI+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G
Sbjct: 179 DAVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAE 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ +C++++A G +H YTLN+ K +L LG
Sbjct: 239 VVAALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLG 274
[220][TOP]
>UniRef100_B1TB42 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia ambifaria
MEX-5 RepID=B1TB42_9BURK
Length = 276
Score = 115 bits (288), Expect = 2e-24
Identities = 56/157 (35%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------ARSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ +A++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN + I L L
Sbjct: 240 VVTSLCQRLVDAGVPGLHFYTLNAASATRTICERLAL 276
[221][TOP]
>UniRef100_Q87V72 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. tomato RepID=Q87V72_PSESM
Length = 281
Score = 115 bits (287), Expect = 2e-24
Identities = 57/157 (36%), Positives = 90/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A ++ DL + +K +AGAD +TQ F++ D + FV
Sbjct: 132 FHIEVAAYPEMHPQ---------ARNFEDDLKHFVTKANAGADSAITQYFFNADSYFNFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++G++ PIVPGIMPI NY R + C +IP I LE D+ ++++A+G
Sbjct: 183 ERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGED 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T+MC++++ G +H YTLN + +LA+ +L L
Sbjct: 243 VITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQL 279
[222][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 115 bits (287), Expect = 2e-24
Identities = 56/157 (35%), Positives = 86/157 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ + DL + KV+AGA +TQ F++ D + FV
Sbjct: 134 FSIEVAAYPEFHPQ---------AQNAEADLNNFRRKVEAGATSAITQYFFNADSYFYFV 184
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
C + G+ PIVPGIMPI NY R + C +IP + LE D+ +++ +G
Sbjct: 185 ERCEKAGLNLPIVPGIMPITNYSNLARFSDMCGAEIPRWVRKQLEAYGDDSASIRKFGEE 244
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++A G +H YTLN + +LA+ +L L
Sbjct: 245 VVTRLCERLLAAGAPGIHFYTLNQAEPSLAVWDNLNL 281
[223][TOP]
>UniRef100_Q2L158 Methylenetetrahydrofolate reductase n=1 Tax=Bordetella avium 197N
RepID=Q2L158_BORA1
Length = 280
Score = 115 bits (287), Expect = 2e-24
Identities = 56/155 (36%), Positives = 88/155 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A DL + SKV AGA+ +TQ F++ D + FV
Sbjct: 133 FHIEVAAYPEMHPQ---------ATSPTADLGHFVSKVQAGANAAITQYFFNADAYFDFV 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ + G+T PIVPGIMPI NY R + C ++P I L D++ +++A+G+
Sbjct: 184 DRAQARGVTIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAFGVD 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ T++C+ ++ HG+ +H YTLN ++ L+I +L
Sbjct: 244 VVTKLCQTLLDHGVPGLHFYTLNQSEATLSIWKNL 278
[224][TOP]
>UniRef100_B8GXY2 Methylenetetrahydrofolate reductase n=2 Tax=Caulobacter vibrioides
RepID=B8GXY2_CAUCN
Length = 314
Score = 115 bits (287), Expect = 2e-24
Identities = 60/161 (37%), Positives = 87/161 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + + YPE HP+ + + D+ LK KVDAGA L ++Q F+D D FL+FV
Sbjct: 155 FEVLVGVYPEKHPE---------SPSLEHDIDVLKQKVDAGATLGISQFFFDLDAFLRFV 205
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R GIT PIVPGIMP+ N+ G +M C+T IP+ + + ++++ E +
Sbjct: 206 DKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTAIPSWLGNLFDGLENDAETRRLIACS 265
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEES 484
+ EMC K+ G + H YTLN AI LG+ E S
Sbjct: 266 VAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVLGVREIS 306
[225][TOP]
>UniRef100_B8F8Q2 Methylenetetrahydrofolate reductase n=1 Tax=Haemophilus parasuis
SH0165 RepID=B8F8Q2_HAEPS
Length = 293
Score = 115 bits (287), Expect = 2e-24
Identities = 59/160 (36%), Positives = 88/160 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++A YPE HP+ A+ Q DL YLK KVDAGA +TQ F+D D +L+F
Sbjct: 143 FEISVAAYPEVHPE---------AKSAQSDLLYLKQKVDAGASRAITQFFFDIDSYLRFR 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C +GI IVPGI+P++N+K +M KIP+ + + + D++ G
Sbjct: 194 DRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGLDDDQTTRNLVGAS 253
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
+ +M K + G+K H YTLN + + AI +LG+ E
Sbjct: 254 IAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE 293
[226][TOP]
>UniRef100_B2I856 Methylenetetrahydrofolate reductase n=2 Tax=Xylella fastidiosa
RepID=B2I856_XYLF2
Length = 275
Score = 115 bits (287), Expect = 2e-24
Identities = 56/156 (35%), Positives = 89/156 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + I YPE HP A DL Y K+KVDAGAD +TQ FY+ D + FV
Sbjct: 128 FHLEIGAYPETHPQ---------ASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFV 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ +++G+T PIV G+MPI+N+ + C +IP I ++ D+ ++++A+G
Sbjct: 179 DAVQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGAD 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
+ T +C++++A G +H YTLN+ K + +L LG
Sbjct: 239 VVTALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLG 274
[227][TOP]
>UniRef100_A1WFN0 Methylenetetrahydrofolate reductase n=1 Tax=Verminephrobacter
eiseniae EF01-2 RepID=A1WFN0_VEREI
Length = 283
Score = 115 bits (287), Expect = 2e-24
Identities = 59/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDL-AYLKSKVDAGADLIVTQLFYDTDIFLKF 178
F I +A YPE HP A + DL AYL+ KV AGAD +TQ FY++D + +F
Sbjct: 136 FHIEVAAYPETHPQ---------ARSPEADLNAYLR-KVQAGADSAITQYFYNSDAYFRF 185
Query: 179 VNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGI 358
V + R++G P+VPGIMPI++ +R + C +IP I L+ D+ ++KA+G+
Sbjct: 186 VEETRRLGADLPVVPGIMPISSSTQLLRFSDACGAEIPRWIRLRLQAFGDDSASIKAFGL 245
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C ++ + G+ +H YTLN + L I LG+
Sbjct: 246 DVVTDLCDRLRSAGVPALHFYTLNQSTATLEICRRLGI 283
[228][TOP]
>UniRef100_Q1N770 Methylenetetrahydrofolate reductase n=1 Tax=Sphingomonas sp. SKA58
RepID=Q1N770_9SPHN
Length = 300
Score = 115 bits (287), Expect = 2e-24
Identities = 60/157 (38%), Positives = 84/157 (53%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I+++ YPE HPD A Q DL LKSK+DAGA +TQ F++ D + +F+
Sbjct: 145 FEISVSAYPEVHPD---------ARDPQSDLDNLKSKLDAGATRAITQFFFEPDTYFRFM 195
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R GI IVPGIMP+ N+ RM C T +PA + E + D A +
Sbjct: 196 DKVRAAGIDAEIVPGIMPVGNFAAVQRMAAMCNTDVPAWMGRLFEGLDDRPAARQLISAT 255
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
L E+C+K+ G++ H YTLN + + AI LGL
Sbjct: 256 LAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGL 292
[229][TOP]
>UniRef100_Q0BJC4 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia ambifaria
AMMD RepID=Q0BJC4_BURCM
Length = 276
Score = 114 bits (286), Expect = 3e-24
Identities = 55/157 (35%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------ARSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ +A++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN + I L +
Sbjct: 240 VVTSLCQRLVDAGVPGLHFYTLNTASATRTICERLAM 276
[230][TOP]
>UniRef100_B4W9S9 Methylenetetrahydrofolate reductase n=1 Tax=Brevundimonas sp. BAL3
RepID=B4W9S9_9CAUL
Length = 318
Score = 114 bits (286), Expect = 3e-24
Identities = 57/160 (35%), Positives = 84/160 (52%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F +T+ YPE HP+ + D+ LK+KVDAGA V+Q F+D D FL+F
Sbjct: 164 FDVTVGAYPEKHPE---------SPSIDHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFR 214
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ R G+T P++PG+MP++N+ G RM G C T IP + A + + D+ E +
Sbjct: 215 DRVRAAGVTIPLIPGVMPVSNFAGLTRMCGACGTSIPDWLKAHFDGLDDDPETRRLLAAS 274
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
+ E C ++ G H YTLN AI LG+ E+
Sbjct: 275 VAAETCARLHEEGFSDFHFYTLNRADLVYAICRVLGVREQ 314
[231][TOP]
>UniRef100_B1YR55 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia ambifaria
RepID=B1YR55_BURA4
Length = 276
Score = 114 bits (286), Expect = 3e-24
Identities = 55/157 (35%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------ARSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ +A++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN + I L +
Sbjct: 240 VVTSLCQRLVDAGVPGLHFYTLNAASATRTICERLAM 276
[232][TOP]
>UniRef100_B0QUF0 Methylenetetrahydrofolate reductase n=1 Tax=Haemophilus parasuis
29755 RepID=B0QUF0_HAEPR
Length = 293
Score = 114 bits (286), Expect = 3e-24
Identities = 58/160 (36%), Positives = 88/160 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++A YPE HP+ A+ Q DL YLK K+DAGA +TQ F+D D +L+F
Sbjct: 143 FEISVAAYPEVHPE---------AKSAQSDLLYLKQKIDAGASRAITQFFFDIDSYLRFR 193
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ C +GI IVPGI+P++N+K +M KIP+ + + + D++ G
Sbjct: 194 DRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGLDDDQTTRNLVGAS 253
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
+ +M K + G+K H YTLN + + AI +LG+ E
Sbjct: 254 IAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE 293
[233][TOP]
>UniRef100_UPI0000E87FC4 metF; 5,10-methylenetetrahydrofolate reductase oxidoreductase
protein n=1 Tax=Methylophilales bacterium HTCC2181
RepID=UPI0000E87FC4
Length = 277
Score = 114 bits (285), Expect = 4e-24
Identities = 57/155 (36%), Positives = 90/155 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP+ + + D+ K K+DAGA +TQ F++ D + KF+
Sbjct: 130 FLIEVAAYPEFHPEALSA---------KDDMDNFKRKIDAGASGAITQFFFNVDAYFKFM 180
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+C++ I PIVPGIMPI N K R + C ++IP + LE D+ E++++YGI
Sbjct: 181 EECQKRSINIPIVPGIMPIYNIKQLSRFSANCGSEIPRWLKMKLEDYGDDLESLRSYGID 240
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ TE+C+ ++ +G+ +VH YTLN I+ +L
Sbjct: 241 VITELCETLIQYGVPSVHFYTLNQSGIITKIINNL 275
[234][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 114 bits (285), Expect = 4e-24
Identities = 51/120 (42%), Positives = 76/120 (63%), Gaps = 1/120 (0%)
Frame = +2
Query: 125 ADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIM 304
+ I+TQLF+ + FLKF+ DC+ IGITCPI+PGI PI Y ++ K ++P EI
Sbjct: 80 SSFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIK 139
Query: 305 AALEPIKDNEEAVKAYGIHLGTEMCKKIMAHG-IKTVHLYTLNMEKSALAILMSLGLIEE 481
+EPIKDN+ A++ YG+ L MC++++ G + +H YTLN E + +L LG+ E
Sbjct: 140 DVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNE 199
[235][TOP]
>UniRef100_Q3ARK5 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
chlorochromatii CaD3 RepID=Q3ARK5_CHLCH
Length = 289
Score = 114 bits (285), Expect = 4e-24
Identities = 62/156 (39%), Positives = 91/156 (58%), Gaps = 1/156 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FG+ +AG+PE HP+ +++ YLK+KVDAGAD IVTQLF+D + FV
Sbjct: 142 FGVGVAGFPEGHPETPNR---------MQEIEYLKAKVDAGADYIVTQLFFDNRDYFDFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGI 358
C+ GIT P++PGIMPI KG IRM+ ++IPA ++ + +N+ V A GI
Sbjct: 193 ERCQLAGITVPVIPGIMPIATKKGMIRMSELALGSRIPAPLIKQV-LAAENDSDVAAIGI 251
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
T ++++ I+ +H YTLNM + L I +L
Sbjct: 252 EWATAQVQELINQHIRGIHFYTLNMADATLKIFRNL 287
[236][TOP]
>UniRef100_Q2STU2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis E264 RepID=Q2STU2_BURTA
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 55/157 (35%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A + DL KV AGA+ +TQ FY+ D + +FV
Sbjct: 129 FRIEVAAYPEYHPQ---------ARSPKADLENFARKVKAGANAAITQYFYNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D ++G+ P+VPGIMPI N+ +R + C ++P I LE D++++++A+G
Sbjct: 180 DDAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN + A+ LGL
Sbjct: 240 VVTGLCRRLIDAGVPGLHFYTLNGAAATKAVCERLGL 276
[237][TOP]
>UniRef100_Q1GX61 Methylenetetrahydrofolate reductase n=1 Tax=Sphingopyxis alaskensis
RepID=Q1GX61_SPHAL
Length = 312
Score = 114 bits (285), Expect = 4e-24
Identities = 60/157 (38%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I++A YPE HPD A+ Q DL LK K+DAGA+ +TQ F+ D FL+F
Sbjct: 154 FDISVAAYPEVHPD---------ADCPQSDLDNLKRKLDAGANRAITQFFFSPDSFLRFR 204
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ GI PI+PGI+P++N RM C T IPA +++ + + D+ A +
Sbjct: 205 DTAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAIPAWMVSLFDGLDDHPAARQLVAAT 264
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ EMC+++ A G++ H YTLN + + AI LGL
Sbjct: 265 VAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLGL 301
[238][TOP]
>UniRef100_B1JTJ6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia MC0-3 RepID=B1JTJ6_BURCC
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 54/157 (34%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP + + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------SRSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ E+++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN+ + I L +
Sbjct: 240 VVTSLCQRLIDAGVPGLHFYTLNLATATRTICERLAV 276
[239][TOP]
>UniRef100_A0K3F1 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia
cenocepacia RepID=A0K3F1_BURCH
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 54/157 (34%), Positives = 89/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP + + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------SRSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ E+++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T +C++++ G+ +H YTLN+ + I L +
Sbjct: 240 VVTNLCQRLIDAGVPGLHFYTLNLATATRTICERLAV 276
[240][TOP]
>UniRef100_A9AD52 Methylenetetrahydrofolate reductase n=4 Tax=Burkholderia
multivorans RepID=A9AD52_BURM1
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 55/151 (36%), Positives = 87/151 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------ARSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ E+++A+G
Sbjct: 180 DDVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
+ T +C++++ G+ +H YTLN + AI
Sbjct: 240 VVTGLCQRLIDAGVPGLHFYTLNAAAATKAI 270
[241][TOP]
>UniRef100_B1G9E6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia graminis
C4D1M RepID=B1G9E6_9BURK
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 55/151 (36%), Positives = 88/151 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP + + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FWIEVAGYPEYHPQ---------SRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAI 454
+ T++CK+++ + +H YTLN + AI
Sbjct: 240 VVTDLCKRLVDAKVPGLHFYTLNGAAATKAI 270
[242][TOP]
>UniRef100_UPI0001744B6A 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B6A
Length = 314
Score = 114 bits (284), Expect = 5e-24
Identities = 62/157 (39%), Positives = 86/157 (54%), Gaps = 1/157 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AG+PE HP P + D +LK+K+DAGAD I TQLF+D F F
Sbjct: 149 FGIGVAGFPEGHPGT-------PNRLLEMD--HLKAKIDAGADYICTQLFFDNRDFHDFC 199
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGI 358
C GI PI+ GI+P+ + G RM ++PA ++ AL ++ + AV G+
Sbjct: 200 ERCELAGIRVPILAGILPVTSLSGLRRMAELAGGARVPARLLKALMKVQHDPAAVLEVGL 259
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLG 469
H TE C +++ HG+ +HLYTLN L IL LG
Sbjct: 260 HHATEQCSELLHHGVSGIHLYTLNQAGPILEILKRLG 296
[243][TOP]
>UniRef100_Q39KN7 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia sp. 383
RepID=Q39KN7_BURS3
Length = 276
Score = 114 bits (284), Expect = 5e-24
Identities = 53/143 (37%), Positives = 84/143 (58%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP A + DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FHIEVAGYPEYHPQ---------ARSPKADLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P + LE D+ E+++A+G
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGAD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLN 430
+ T +C++++ G+ +H YTLN
Sbjct: 240 VVTSLCQRLVDAGVPGLHFYTLN 262
[244][TOP]
>UniRef100_Q13T38 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia xenovorans
LB400 RepID=Q13T38_BURXL
Length = 276
Score = 114 bits (284), Expect = 5e-24
Identities = 55/157 (35%), Positives = 91/157 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +AGYPE HP + ++DL KV AGA+ +TQ F++ D + +FV
Sbjct: 129 FCIEVAGYPEYHPQ---------SRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFV 179
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R++G+ PIVPGIMPI N+ +R + C ++P I LE D+ E+++A+G+
Sbjct: 180 DDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLD 239
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T++C++++ + +H YTLN + AI L +
Sbjct: 240 VVTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLNV 276
[245][TOP]
>UniRef100_B4SJY7 Methylenetetrahydrofolate reductase n=1 Tax=Stenotrophomonas
maltophilia R551-3 RepID=B4SJY7_STRM5
Length = 275
Score = 114 bits (284), Expect = 5e-24
Identities = 56/155 (36%), Positives = 89/155 (57%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I + YPE HP +D LA DL + K+K+DAGAD +TQ F++ D + FV
Sbjct: 128 FHIEVGAYPETHPQA--SDALA-------DLKHFKAKIDAGADAAITQYFFNPDAYFHFV 178
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
++ R++G+ PI PGIMPI N+ R + C +IP I ++ D+ E+V+A+G
Sbjct: 179 DEVRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTE 238
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
+ +C++++ G +H YTLN+ K ++L L
Sbjct: 239 VVARLCQRLIEDGAPGLHFYTLNLAKPTTSVLKLL 273
[246][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 114 bits (284), Expect = 5e-24
Identities = 62/156 (39%), Positives = 89/156 (57%), Gaps = 1/156 (0%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
FGI +AG+PE HP ++ YLK KVDAGAD IVTQLF+D + FV
Sbjct: 142 FGIGVAGFPEGHPQTPNR---------LDEITYLKEKVDAGADYIVTQLFFDNRDYFDFV 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFC-KTKIPAEIMAALEPIKDNEEAVKAYGI 358
+ C GIT PI+PGIMP+ KG IRM+ +IPAE++ + D++ +A GI
Sbjct: 193 DRCALEGITVPIIPGIMPVTTKKGLIRMSELALGARIPAELLKEVIEAPDDQSVAEA-GI 251
Query: 359 HLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSL 466
T+ ++++ H IK +H YTLN ++ I ++
Sbjct: 252 RWATKQVRELIDHHIKGIHFYTLNHAEATRMIFNNI 287
[247][TOP]
>UniRef100_B1J2Y7 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida W619
RepID=B1J2Y7_PSEPW
Length = 281
Score = 114 bits (284), Expect = 5e-24
Identities = 58/157 (36%), Positives = 88/157 (56%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F + +A YPE HP A ++ DLA KV AGAD +TQ F++ D + FV
Sbjct: 132 FHLEVAAYPEMHPQ---------ARNFEADLANFVHKVKAGADSAITQYFFNADSYFYFV 182
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+++G+ P+VPGIMPI NY R + C +IP I LE D+ +++A+G
Sbjct: 183 ERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEE 242
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
+ T MC++++ G +H YTLN +++LAI +L L
Sbjct: 243 VITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKL 279
[248][TOP]
>UniRef100_A6T2Y7 Methylenetetrahydrofolate reductase n=1 Tax=Janthinobacterium sp.
Marseille RepID=A6T2Y7_JANMA
Length = 283
Score = 114 bits (284), Expect = 5e-24
Identities = 57/160 (35%), Positives = 87/160 (54%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I +A YPE HP A+ Q D+A K AGAD +TQ FY+ D + +FV
Sbjct: 133 FHIEVAAYPEMHPQ---------AKSPQDDIASFVRKAKAGADSAITQYFYNADAYFRFV 183
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+D R+ G P+ GIMPI NY +R + C +IP I L D+ E+++A+G+
Sbjct: 184 DDARKAGTDIPVTAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDSESIRAFGLD 243
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIEE 481
+ T++C++++A G +H YTLN + I L L ++
Sbjct: 244 VVTDLCERLLAGGAPGLHFYTLNQAVATHTIWTRLNLSQK 283
[249][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 114 bits (284), Expect = 5e-24
Identities = 59/159 (37%), Positives = 89/159 (55%)
Frame = +2
Query: 2 FGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYLKSKVDAGADLIVTQLFYDTDIFLKFV 181
F I A Y E H + ++ + DL YLK KVD G D +VTQLF+D +F F+
Sbjct: 142 FCIAAAAYVEGHVN---------SKRLKDDLLYLKQKVDTGVDFLVTQLFFDNRLFYDFL 192
Query: 182 NDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIH 361
+ IGITCPI PGIMPI R+T C IPA+++ ++ DN+E ++ GI
Sbjct: 193 DKTASIGITCPITPGIMPIFKADQIKRITYLCGASIPAKLVIMMDKYGDNDEDMRKAGIE 252
Query: 362 LGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGLIE 478
+ + ++ +G+ +HL T+N KS IL ++GL++
Sbjct: 253 YASNQIRDLIDNGVDGIHLLTMNRPKSTREILTNIGLLK 291
[250][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 113 bits (283), Expect = 6e-24
Identities = 48/120 (40%), Positives = 78/120 (65%)
Frame = +2
Query: 113 VDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIP 292
+DAGAD +TQ FY+ D + +FV++C ++G+ PI+PGIMPI NY +R + C T+IP
Sbjct: 1 MDAGADSAITQYFYNPDAYFRFVDECSRLGVEIPIIPGIMPITNYSSLVRFSDACGTEIP 60
Query: 293 AEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL 472
I LE D+ E+++A+G+ + TE+C++++ G +H YT+N + L + LGL
Sbjct: 61 RWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEGGAPGLHFYTMNQSEPTLRLCDRLGL 120