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[1][TOP]
>UniRef100_C6TGN4 Putative uncharacterized protein n=1 Tax=Glycine max
RepID=C6TGN4_SOYBN
Length = 232
Score = 249 bits (637), Expect = 8e-65
Identities = 124/182 (68%), Positives = 144/182 (79%), Gaps = 3/182 (1%)
Frame = +2
Query: 38 INRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEE 217
IN +SIEYAVK LL+ LGED+NREGI KTP RVAKA FEGTRGY+Q+ I+EGALFPE
Sbjct: 30 INTTSIEYAVKVLLMDLGEDINREGIIKTPHRVAKALFEGTRGYKQSAKEIVEGALFPEA 89
Query: 218 GLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRV 397
G+D+T K+GH G LV VRD++ YSYCESC+LPF KCHVGY+PS QRV+GLSKL RV
Sbjct: 90 GVDST-KVGHAGE---LVIVRDLEFYSYCESCMLPFYFKCHVGYVPSGQRVLGLSKLSRV 145
Query: 398 AEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNI 568
FAKR QEPQRLANE+C ALH+GI+P GVA++LQCTHI P + FDSNHKG V
Sbjct: 146 TNVFAKRFQEPQRLANEVCSALHQGIEPAGVAVVLQCTHINIPDTESNFFDSNHKGLVET 205
Query: 569 LV 574
LV
Sbjct: 206 LV 207
[2][TOP]
>UniRef100_UPI0001982DCA PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001982DCA
Length = 455
Score = 249 bits (636), Expect = 1e-64
Identities = 122/177 (68%), Positives = 143/177 (80%), Gaps = 3/177 (1%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
IE AVK LL GLGED+NREGIRKTP RVAKA EGTRGYRQ +I++GALFPE GLD
Sbjct: 30 IEEAVKVLLQGLGEDINREGIRKTPARVAKALCEGTRGYRQKAKDIVQGALFPEAGLDEG 89
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+GH GGVGGLV VRD+DL+SYCESCLLPFQ+KCHVGY+PS Q+VVGLSKL RVA+ FA
Sbjct: 90 --VGHAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGQQVVGLSKLSRVADVFA 147
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
KRLQ+PQRLA+E+C AL+ GI+P GVA++LQC HI FP + DS H+ WV + V
Sbjct: 148 KRLQDPQRLADEVCSALNHGIKPTGVAVVLQCLHIHFPNLELGFLDSTHQEWVKVSV 204
[3][TOP]
>UniRef100_B9IBE3 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9IBE3_POPTR
Length = 465
Score = 248 bits (634), Expect = 2e-64
Identities = 119/178 (66%), Positives = 144/178 (80%), Gaps = 3/178 (1%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE AVK LL GLGED+NREG++KTP RVAKA EGT+GY+Q V I++GALFPE GLD+
Sbjct: 34 AIEDAVKVLLQGLGEDINREGLKKTPLRVAKALREGTKGYKQRVKEIVQGALFPEVGLDD 93
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
++G GG GGLV VRD+DL+SYCESCLLPFQ+KC +GY+PS QRVVGLSKL RVA+ F
Sbjct: 94 --EVGQAGGAGGLVIVRDLDLFSYCESCLLPFQVKCQIGYVPSGQRVVGLSKLSRVADVF 151
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
AKRLQ+PQRLA+EIC ALH G+ P GVA++LQC HI FP + DSNH+GWV +V
Sbjct: 152 AKRLQDPQRLADEICSALHHGVMPAGVAVVLQCLHIQFPNIESLFLDSNHQGWVKAVV 209
[4][TOP]
>UniRef100_B9SYL5 GTP cyclohydrolase I, putative n=1 Tax=Ricinus communis
RepID=B9SYL5_RICCO
Length = 469
Score = 248 bits (633), Expect = 2e-64
Identities = 122/178 (68%), Positives = 140/178 (78%), Gaps = 3/178 (1%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE AV LL GLGED+NREG++KTP RVAKA G RGY+QN +I+ ALFPE GLDN
Sbjct: 34 AIENAVSVLLQGLGEDINREGLKKTPLRVAKALLYGNRGYKQNANDIVHSALFPESGLDN 93
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+GH GG GGLV VRD+DL+SYCESCLLPFQ+KCH+GY+PS QRVVGLSKL RVA+ F
Sbjct: 94 A--VGHAGGAGGLVIVRDLDLFSYCESCLLPFQVKCHIGYVPSGQRVVGLSKLSRVADVF 151
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
AKRLQ PQRLANEIC ALH GI+P GVA+ILQC HI FP DSNH+G+V LV
Sbjct: 152 AKRLQGPQRLANEICSALHHGIKPAGVAVILQCLHIHFPSFGSLLLDSNHQGFVKALV 209
[5][TOP]
>UniRef100_B9GQM6 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GQM6_POPTR
Length = 465
Score = 246 bits (627), Expect = 1e-63
Identities = 123/194 (63%), Positives = 150/194 (77%), Gaps = 3/194 (1%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
E++ L E + +IE AVK LL GLGED+NREG++KTP RVAKA EGT+GY+Q
Sbjct: 18 ELDCLDLGFEDQLETVAIEDAVKVLLQGLGEDINREGLKKTPLRVAKALREGTKGYKQKA 77
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+I++ ALFPE GLD+ +GH GG GGLV VRD+DL+SYCESCLLPFQ+KC +GY+PS
Sbjct: 78 KDIVQSALFPEVGLDDA--VGHAGGAGGLVIVRDLDLFSYCESCLLPFQVKCQIGYVPSG 135
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD-- 535
QRVVGLSKL RVA+ FAKRLQ+PQRLA+EIC ALH GI+P GVA+ILQC+HI FP +
Sbjct: 136 QRVVGLSKLSRVADVFAKRLQDPQRLADEICSALHLGIKPAGVAVILQCSHIHFPNIEPP 195
Query: 536 -FDSNHKGWVNILV 574
DSN +GWV LV
Sbjct: 196 FLDSNLQGWVKALV 209
[6][TOP]
>UniRef100_A7QEB5 Chromosome chr1 scaffold_84, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QEB5_VITVI
Length = 445
Score = 244 bits (623), Expect = 3e-63
Identities = 120/178 (67%), Positives = 143/178 (80%), Gaps = 3/178 (1%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE AVK LL GLGED+NREG+ KTP RVAKA EGTRGYRQ +I++GALFPE GL+N
Sbjct: 19 TIEEAVKVLLQGLGEDINREGLSKTPARVAKALREGTRGYRQKAKDIVQGALFPEAGLNN 78
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
IGH GGVGGLV VRD+DL+SYCESCLLPFQ+KCHVGY+PS Q VVGLSKL RVA+ F
Sbjct: 79 G--IGHAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGQCVVGLSKLSRVADVF 136
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
AKRLQ+PQRLA+++C AL+ GI+P GVA++LQC HI FP + DS H+ WV + V
Sbjct: 137 AKRLQDPQRLADDVCSALNHGIKPAGVAVVLQCLHIHFPNLELGFLDSTHQEWVTVSV 194
[7][TOP]
>UniRef100_A5BLJ4 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BLJ4_VITVI
Length = 445
Score = 244 bits (623), Expect = 3e-63
Identities = 120/178 (67%), Positives = 143/178 (80%), Gaps = 3/178 (1%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE AVK LL GLGED+NREG+ KTP RVAKA EGTRGYRQ +I++GALFPE GL+N
Sbjct: 19 AIEEAVKVLLQGLGEDINREGLSKTPARVAKALREGTRGYRQKAKDIVQGALFPEAGLNN 78
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
IGH GGVGGLV VRD+DL+SYCESCLLPFQ+KCHVGY+PS Q VVGLSKL RVA+ F
Sbjct: 79 G--IGHAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGQCVVGLSKLSRVADVF 136
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
AKRLQ+PQRLA+++C AL+ GI+P GVA++LQC HI FP + DS H+ WV + V
Sbjct: 137 AKRLQDPQRLADDVCSALNHGIKPAGVAVVLQCLHIHFPNLELGLLDSTHQEWVKVSV 194
[8][TOP]
>UniRef100_Q8VYU3 GTP cyclohydrolase I n=1 Tax=Solanum lycopersicum
RepID=Q8VYU3_SOLLC
Length = 456
Score = 238 bits (608), Expect = 2e-61
Identities = 117/175 (66%), Positives = 140/175 (80%), Gaps = 3/175 (1%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
I+ AV+ LL GLGED+NREGI+KTPFRVAKA +GTRGY+Q V +I+ GALFPE GL+
Sbjct: 32 IQDAVRVLLQGLGEDINREGIKKTPFRVAKALRQGTRGYKQKVNDIVHGALFPEAGLEGG 91
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+ G GGVGGLV VRD+DL+SYCESCLLPFQ+KCHVGY+PS +RVVGLSKL RVA+ FA
Sbjct: 92 S--GQAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGKRVVGLSKLSRVADIFA 149
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNI 568
KRLQ PQRLA+E+C AL GI+P GVA++LQC HI FP + DS +GWV I
Sbjct: 150 KRLQSPQRLADEVCTALQHGIKPTGVAVVLQCMHIHFPNFESAFLDSTSQGWVKI 204
[9][TOP]
>UniRef100_Q9SFV7 GTP cyclohydrolase I n=1 Tax=Arabidopsis thaliana
RepID=Q9SFV7_ARATH
Length = 466
Score = 231 bits (589), Expect = 3e-59
Identities = 113/179 (63%), Positives = 140/179 (78%), Gaps = 4/179 (2%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+I+ AVK LL GL EDVNREGI+KTPFRVAKA EGTRGY+Q V + ++ ALFPE GLD
Sbjct: 34 AIQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDE 93
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+G GGVGGLV VRD+D YSYCESCLLPF +KCH+GY+PS QRV+GLSK RV + F
Sbjct: 94 G--VGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVF 151
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD----SNHKGWVNILV 574
AKRLQ+PQRLA++IC AL ++P GVA++L+C+HI FP D D S+H+G+V +LV
Sbjct: 152 AKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHIHFPSLDLDSLNLSSHRGFVKLLV 210
[10][TOP]
>UniRef100_Q8S3C2 GTP cyclohydrolase I n=1 Tax=Arabidopsis thaliana
RepID=Q8S3C2_ARATH
Length = 466
Score = 231 bits (589), Expect = 3e-59
Identities = 113/179 (63%), Positives = 140/179 (78%), Gaps = 4/179 (2%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+I+ AVK LL GL EDVNREGI+KTPFRVAKA EGTRGY+Q V + ++ ALFPE GLD
Sbjct: 34 AIQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDE 93
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+G GGVGGLV VRD+D YSYCESCLLPF +KCH+GY+PS QRV+GLSK RV + F
Sbjct: 94 G--VGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVF 151
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD----SNHKGWVNILV 574
AKRLQ+PQRLA++IC AL ++P GVA++L+C+HI FP D D S+H+G+V +LV
Sbjct: 152 AKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHIHFPSLDLDSLNLSSHRGFVKLLV 210
[11][TOP]
>UniRef100_Q3EBB1 Putative uncharacterized protein At3g07270.2 n=1 Tax=Arabidopsis
thaliana RepID=Q3EBB1_ARATH
Length = 466
Score = 231 bits (589), Expect = 3e-59
Identities = 113/179 (63%), Positives = 140/179 (78%), Gaps = 4/179 (2%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+I+ AVK LL GL EDVNREGI+KTPFRVAKA EGTRGY+Q V + ++ ALFPE GLD
Sbjct: 34 AIQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDE 93
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+G GGVGGLV VRD+D YSYCESCLLPF +KCH+GY+PS QRV+GLSK RV + F
Sbjct: 94 G--VGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVF 151
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD----SNHKGWVNILV 574
AKRLQ+PQRLA++IC AL ++P GVA++L+C+HI FP D D S+H+G+V +LV
Sbjct: 152 AKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHIHFPSLDLDSLNLSSHRGFVKLLV 210
[12][TOP]
>UniRef100_A3AYB4 Putative uncharacterized protein n=1 Tax=Oryza sativa Japonica
Group RepID=A3AYB4_ORYSJ
Length = 483
Score = 226 bits (576), Expect = 1e-57
Identities = 114/188 (60%), Positives = 138/188 (73%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
E + LV D + ++E AV+ LLLGLGED REG+R+TP RVAKAF +GTRGY+Q V
Sbjct: 25 EEDDLVEGDGEAAAADAMEPAVRALLLGLGEDARREGLRRTPKRVAKAFRDGTRGYKQKV 84
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+I++GALFPE G+D + G GG GG V VRDIDL+SYCESCLLPF I+ HVGY+PS
Sbjct: 85 KDIVQGALFPEVGVDK--RTGSAGGTGGQVVVRDIDLFSYCESCLLPFSIQFHVGYVPSG 142
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD 541
RVVGLSKL RVA+ FAKRLQ PQRLA+E+C ALH IQP GVA+ LQC HIP P
Sbjct: 143 GRVVGLSKLSRVADVFAKRLQNPQRLASEVCGALHASIQPAGVAVALQCWHIPLPENLKC 202
Query: 542 SNHKGWVN 565
+GW++
Sbjct: 203 KTLQGWIS 210
[13][TOP]
>UniRef100_A2XYL4 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2XYL4_ORYSI
Length = 483
Score = 225 bits (573), Expect = 2e-57
Identities = 113/188 (60%), Positives = 138/188 (73%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
E + LV D + ++E AV+ LLLGLGED REG+R+TP RVAKAF +GTRGY+Q V
Sbjct: 25 EEDDLVEGDGEAAAADAMEPAVRALLLGLGEDARREGLRRTPKRVAKAFRDGTRGYKQKV 84
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+I++GALFPE G+D + G GG GG V VRDIDL+SYCESCLLPF I+ HVGY+PS
Sbjct: 85 KDIVQGALFPEVGVDK--RTGSAGGTGGQVVVRDIDLFSYCESCLLPFSIQFHVGYVPSG 142
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD 541
RVVGLSKL RVA+ FAKRLQ PQRLA+E+C ALH I+P GVA+ LQC HIP P
Sbjct: 143 GRVVGLSKLSRVADVFAKRLQNPQRLASEVCGALHASIEPAGVAVALQCWHIPLPENLKC 202
Query: 542 SNHKGWVN 565
+GW++
Sbjct: 203 KTLQGWIS 210
[14][TOP]
>UniRef100_B6TEC8 GTP cyclohydrolase I 1 n=1 Tax=Zea mays RepID=B6TEC8_MAIZE
Length = 468
Score = 223 bits (569), Expect = 6e-57
Identities = 111/171 (64%), Positives = 131/171 (76%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E AV+ LLLGLGED REG+ +TP RVAKAF +GTRGYRQ V +I++GALFPE G+D
Sbjct: 37 AVEPAVRALLLGLGEDDRREGLLRTPKRVAKAFRDGTRGYRQKVKDIVQGALFPEVGVDK 96
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ G GG GG V VRDI+L+SYCESCLLPF I+CHVGY+PS RVVGLSKL RV++ F
Sbjct: 97 --RTGSAGGTGGQVVVRDIELFSYCESCLLPFSIQCHVGYVPSGGRVVGLSKLSRVSDVF 154
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNHKGWV 562
AKRLQ PQRLANEIC ALH IQP GVA+ LQC HIP P +GW+
Sbjct: 155 AKRLQNPQRLANEICGALHASIQPAGVAVALQCWHIPLPENLECKTLEGWI 205
[15][TOP]
>UniRef100_B4FH02 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FH02_MAIZE
Length = 475
Score = 223 bits (568), Expect = 8e-57
Identities = 110/171 (64%), Positives = 131/171 (76%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E AV+ LLLGLGED REG+R+TP RV+KAF +GTRGYRQ V +I+ GALFPE G+D
Sbjct: 39 AMEPAVRALLLGLGEDDRREGLRRTPKRVSKAFRDGTRGYRQKVKDIVRGALFPEVGVDK 98
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ G GG GG V VRDI+L+SYCESCLLPF I+CHVGY+PS RVVGLSKL RV++ F
Sbjct: 99 --RTGSAGGTGGQVVVRDIELFSYCESCLLPFSIQCHVGYVPSGGRVVGLSKLSRVSDVF 156
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNHKGWV 562
AKRLQ PQRLANE+C ALH IQP GVA+ LQC HIP P +GW+
Sbjct: 157 AKRLQNPQRLANEVCGALHASIQPAGVAVALQCWHIPLPENLECKTLQGWI 207
[16][TOP]
>UniRef100_B0EVI7 GTP cyclohydrolase 1 isoform TaC n=1 Tax=Triticum aestivum
RepID=B0EVI7_WHEAT
Length = 480
Score = 223 bits (568), Expect = 8e-57
Identities = 111/169 (65%), Positives = 131/169 (77%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E AV+ LL GLGED REG+R+TP RVAKAF +GTRGYRQ V +I++GALFPE G+D
Sbjct: 38 AMEPAVRALLAGLGEDDRREGLRRTPKRVAKAFRDGTRGYRQKVKDIVQGALFPEVGVDK 97
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ G GG GG V VRDIDLYSYCESCLLPF I+CHVGY+PS RVVGLSKL RVA+ F
Sbjct: 98 --RTGSAGGTGGQVVVRDIDLYSYCESCLLPFSIQCHVGYVPSGGRVVGLSKLSRVADVF 155
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNHKG 556
AKR Q PQRLANE+C ALH IQP GVA+ +QC HIP P ++F + G
Sbjct: 156 AKRFQNPQRLANEVCGALHASIQPAGVAVAMQCWHIPLP-ENFKCKNSG 203
[17][TOP]
>UniRef100_B0EVI8 GTP cyclohydrolase 1 isoform TaA n=1 Tax=Triticum aestivum
RepID=B0EVI8_WHEAT
Length = 480
Score = 220 bits (561), Expect = 5e-56
Identities = 109/159 (68%), Positives = 125/159 (78%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE AV+ LL GLGED REG+ +TP RVAKAF +GTRGYRQ V +I++GALFPE G+D
Sbjct: 38 AIEPAVRALLAGLGEDDRREGLCRTPKRVAKAFRDGTRGYRQKVKDIVQGALFPEVGVDK 97
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ G GG GG V VRDIDLYSYCESCLLPF I+CHVGY+PS RVVGLSKL RVA+ F
Sbjct: 98 --RTGSAGGTGGQVVVRDIDLYSYCESCLLPFSIQCHVGYVPSGGRVVGLSKLSRVADVF 155
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFP 526
AKR Q PQRLANE+C ALH IQP GVA+ +QC HIP P
Sbjct: 156 AKRFQNPQRLANEVCGALHVSIQPAGVAVAMQCWHIPLP 194
[18][TOP]
>UniRef100_A5BKQ2 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BKQ2_VITVI
Length = 435
Score = 200 bits (508), Expect = 7e-50
Identities = 106/177 (59%), Positives = 124/177 (70%), Gaps = 3/177 (1%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
IE AVK LL GLGED+NREGIRKTP RVAKA EGTRGYRQ +I++GALFPE GLD
Sbjct: 30 IEEAVKVLLQGLGEDINREGIRKTPARVAKALCEGTRGYRQKAKDIVQGALFPEAGLDEG 89
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+GH GGVGGLV KCHVGY+PS Q+VVGLSKL RVA+ FA
Sbjct: 90 --VGHAGGVGGLV--------------------KCHVGYVPSGQQVVGLSKLSRVADVFA 127
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKD---FDSNHKGWVNILV 574
KRLQ+PQRLA+E+C AL+ GI+P GVA++LQC HI FP + DS H+ WV + V
Sbjct: 128 KRLQDPQRLADEVCSALNHGIKPAGVAVVLQCLHIHFPNLELGFLDSTHQEWVKVSV 184
[19][TOP]
>UniRef100_A9S209 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
patens RepID=A9S209_PHYPA
Length = 434
Score = 195 bits (496), Expect = 2e-48
Identities = 99/178 (55%), Positives = 131/178 (73%), Gaps = 7/178 (3%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AVK LL+GLGEDVNR+G+ KTP RVA+AF + TRGYRQ+ +++ GALF E G +N
Sbjct: 6 AVKVLLVGLGEDVNRDGLLKTPLRVAQAFQDATRGYRQSAKDVVGGALFMEPGASGSN-- 63
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G GGG GG+V VR++DL++ CE+CLLPF+I+CH+ YIP +RVVGLSKLPRVAE FAK+L
Sbjct: 64 GSGGGCGGIVVVRNVDLFALCEACLLPFRIRCHIAYIPVGERVVGLSKLPRVAEIFAKKL 123
Query: 422 QEPQRLANEICLALHEGIQPQ--GVAIILQCTHIPFP-----YKDFDSNHKGWVNILV 574
Q P R ANE+ L+L E +QP+ GVA+ ++ H+ +P D +S H GWV+ V
Sbjct: 124 QNPHRFANEVVLSLTEALQPEPLGVAVAVESWHLQWPGESGVVADLES-HVGWVSSTV 180
[20][TOP]
>UniRef100_B2CHJ5 GTP cyclohydrolase 1 isoform TaA n=1 Tax=Hordeum vulgare
RepID=B2CHJ5_HORVU
Length = 480
Score = 194 bits (494), Expect = 3e-48
Identities = 100/159 (62%), Positives = 117/159 (73%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E AV+ LL GLGED REG+R+TP RVAKAF +GTRGYRQ V +I+ GALFPE G+D
Sbjct: 38 AMEPAVRALLAGLGEDDRREGLRRTPKRVAKAFRDGTRGYRQKVKDIVLGALFPEVGVDK 97
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ G GG GG V DIDLYSY ESCLL + C VGY+PS RVVGLSKL RVA+ F
Sbjct: 98 --RTGSAGGTGGQVVEPDIDLYSYWESCLLSSSLPCSVGYVPSGGRVVGLSKLSRVADVF 155
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFP 526
AKR Q PQRLANE+C ALH IQP GVA+ ++ HIP P
Sbjct: 156 AKRFQNPQRLANEVCGALHASIQPAGVAVAMEGWHIPLP 194
[21][TOP]
>UniRef100_A5AY84 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5AY84_VITVI
Length = 404
Score = 193 bits (491), Expect = 7e-48
Identities = 92/140 (65%), Positives = 112/140 (80%), Gaps = 3/140 (2%)
Frame = +2
Query: 164 GYRQNVLNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHV 343
GYRQ +I++GALFPE GL+N IGH GGVGGLV VRD+DL+SYCESCLLPFQ+KCHV
Sbjct: 16 GYRQKAKDIVQGALFPEAGLNNG--IGHAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHV 73
Query: 344 GYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPF 523
GY+PS Q VVGLSKL RVA+ FAKRLQ+PQRLA+++C AL+ GI+P GVA++LQC HI F
Sbjct: 74 GYVPSGQCVVGLSKLSRVADVFAKRLQDPQRLADDVCSALNHGIKPAGVAVVLQCLHIHF 133
Query: 524 PYKD---FDSNHKGWVNILV 574
P + DS H+ WV + V
Sbjct: 134 PNLELGFLDSTHQEWVKVSV 153
[22][TOP]
>UniRef100_A9SYS9 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9SYS9_PHYPA
Length = 432
Score = 179 bits (453), Expect = 2e-43
Identities = 90/172 (52%), Positives = 124/172 (72%), Gaps = 5/172 (2%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AVK LL GLGEDV+R+G+ KTP RVA+AF T+GYRQ +++ GALF E G TN
Sbjct: 4 AVKVLLDGLGEDVSRDGLLKTPLRVAQAFQGATKGYRQAAKDVVGGALFMEPGTGGTN-- 61
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G GGG GG+V VR+++L++ CE+CLLPF+I+CH+ Y+P +RVVGLSKLPRVAE FAK+L
Sbjct: 62 GSGGGCGGMVVVRNVELFALCEACLLPFRIRCHIAYVPVGERVVGLSKLPRVAEIFAKKL 121
Query: 422 QEPQRLANEICLALHEGIQPQ--GVAIILQCTHIPFPYKDFDSN---HKGWV 562
Q P+R A E+ +L E +QP+ GVA+ ++ H+ +P ++ + GWV
Sbjct: 122 QNPRRFAYEVASSLTEALQPEPLGVAVAVESWHLQWPGNGVAADLEKYVGWV 173
[23][TOP]
>UniRef100_A7QSC6 Chromosome chr3 scaffold_158, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QSC6_VITVI
Length = 214
Score = 161 bits (408), Expect = 3e-38
Identities = 85/155 (54%), Positives = 107/155 (69%), Gaps = 1/155 (0%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
IE AVK LL GLGED+NREGIRKTP RVAKA EGTRGYRQ +I++GALFPE
Sbjct: 30 IEEAVKVLLQGLGEDINREGIRKTPARVAKALCEGTRGYRQKAKDIVQGALFPE------ 83
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPR-VAEAF 409
VGGLV VRD+DL+SYCESCLLPFQ+KCHVGY+PS Q+VVGLSKL R + +
Sbjct: 84 -------AVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGQQVVGLSKLSRSIVHFY 136
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTH 514
+LQ +RL ++ + + V ++++ +H
Sbjct: 137 GFKLQVQERLTRQVSETV-SSLLGGDVIVVVEASH 170
[24][TOP]
>UniRef100_Q0J9B5 Os04g0662700 protein (Fragment) n=1 Tax=Oryza sativa Japonica Group
RepID=Q0J9B5_ORYSJ
Length = 399
Score = 146 bits (368), Expect = 1e-33
Identities = 70/112 (62%), Positives = 82/112 (73%)
Frame = +2
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
T + GG GG V VRD+DL+SYCESCLLPF I+ HVGY+PS RVVGLSKL RVA+ F
Sbjct: 15 TRGLVRAGGTGGQVVVRDMDLFSYCESCLLPFSIQFHVGYVPSGGRVVGLSKLSRVADVF 74
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNHKGWVN 565
AKRLQ PQRLA+E+C ALH IQP GVA+ LQC HIP P +GW++
Sbjct: 75 AKRLQNPQRLASEVCGALHASIQPAGVAVALQCWHIPLPENLKCKTLQGWIS 126
[25][TOP]
>UniRef100_Q968X8 GTP cyclohydrolase I n=2 Tax=Physarum polycephalum
RepID=Q968X8_PHYPO
Length = 228
Score = 142 bits (359), Expect = 1e-32
Identities = 73/167 (43%), Positives = 111/167 (66%)
Frame = +2
Query: 17 VSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
+S D SI + +++L+ +GED +REG+++TP R+AKA T+GY Q++ +++
Sbjct: 36 LSKDNCDKQLQSIADSTRNILVNIGEDPDREGLQQTPMRMAKAMMFFTQGYEQSLSDVLN 95
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
GA+F E+ + +V VRDID++S CE L+PF KCH+GYIP N +V+G
Sbjct: 96 GAIFNEDHNE-------------MVVVRDIDIFSLCEHHLVPFFGKCHIGYIP-NGKVLG 141
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+AE FA+RLQ +RL +I LAL E IQP GVA++++ +H+
Sbjct: 142 LSKLARIAEIFARRLQVQERLTRQIALALEEAIQPLGVAVVIEASHM 188
[26][TOP]
>UniRef100_B2WLS0 GTP cyclohydrolase I n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WLS0_PYRTR
Length = 329
Score = 140 bits (353), Expect = 7e-32
Identities = 75/169 (44%), Positives = 111/169 (65%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
K + +E + N + + AV+ +L LGED +REG+ TP R AKA T+GY +N+ +I
Sbjct: 133 KEATEEEKAANLAKLSGAVRTMLECLGEDPDREGLLDTPERYAKALLFFTKGYEENLRDI 192
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E+ + LV VRDI+++S CE L+PF K H+GYIP N+RV
Sbjct: 193 VNGAVFHEDHDE-------------LVIVRDIEIFSLCEHHLVPFTGKMHIGYIP-NRRV 238
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSKL R+AE FA+RLQ +RL ++ LAL E +QPQGVA++++ +H+
Sbjct: 239 IGLSKLARIAEMFARRLQVQERLTKQVALALSEMLQPQGVAVVVESSHL 287
[27][TOP]
>UniRef100_C1ED74 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1ED74_9CHLO
Length = 564
Score = 139 bits (351), Expect = 1e-31
Identities = 78/185 (42%), Positives = 109/185 (58%), Gaps = 21/185 (11%)
Frame = +2
Query: 32 VSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP 211
V ++R +E +V+ +L LGEDV+REG+ TP RVAKA RGY + ++ + ALF
Sbjct: 18 VEVDRDELERSVRAMLEALGEDVHREGLADTPKRVAKAMAFAVRGYGMSAIDAVGSALFH 77
Query: 212 EEGLDN-------------TNKIGHGGGVG-------GLVFVRDIDLYSYCESCLLPFQI 331
E GL++ T GG V G+V +RD+ +S E LLPF
Sbjct: 78 EPGLESDEANAAIEAERAATGAERSGGAVDDHLLARPGVVLIRDVPFFSTAEDSLLPFYG 137
Query: 332 KCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCT 511
+ HVGY+PS ++VGLSK+ R+AE FA+RLQ P RLA +I ALHEG P+GV ++L+
Sbjct: 138 RAHVGYVPSRGQIVGLSKVARLAEVFARRLQNPNRLAADIATALHEGAAPRGVHVVLEAA 197
Query: 512 HI-PF 523
+ PF
Sbjct: 198 QMGPF 202
[28][TOP]
>UniRef100_Q968X9 GTP cyclohydrolase I n=1 Tax=Physarum polycephalum
RepID=Q968X9_PHYPO
Length = 195
Score = 139 bits (349), Expect = 2e-31
Identities = 72/163 (44%), Positives = 108/163 (66%)
Frame = +2
Query: 17 VSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
+S D SI + +++L+ +GED +REG+++TP R+AKA T+GY Q++ +++
Sbjct: 36 LSKDNCDKQLQSIADSTRNILVNIGEDPDREGLQQTPMRMAKAMMFFTQGYEQSLSDVLN 95
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
GA+F E+ + +V VRDID++S CE L+PF KCH+GYIP N +V+G
Sbjct: 96 GAIFNEDHNE-------------MVVVRDIDIFSLCEHHLVPFFGKCHIGYIP-NGKVLG 141
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQ 505
LSKL R+AE FA+RLQ +RL +I LAL E IQP GVA++++
Sbjct: 142 LSKLARIAEIFARRLQVQERLTRQIALALEEAIQPLGVAVVIE 184
[29][TOP]
>UniRef100_Q0UAF8 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UAF8_PHANO
Length = 325
Score = 137 bits (344), Expect = 8e-31
Identities = 73/169 (43%), Positives = 109/169 (64%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
K + +E + AV+ +L LGED +REG+R TP R AKA T+GY +N+ +I
Sbjct: 131 KEATEEEKKERLEKLSGAVRTMLECLGEDPDREGLRDTPDRYAKALLFFTKGYEENLRDI 190
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E+ + LV V+DI+++S CE L+PF K H+GYIP N+RV
Sbjct: 191 VNGAVFHEDHDE-------------LVIVKDIEIFSLCEHHLVPFTGKMHIGYIP-NRRV 236
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSKL R+AE F++RLQ +RL ++ LAL E +QPQGVA++++ +H+
Sbjct: 237 IGLSKLARIAEMFSRRLQVQERLTKQVALALSEMLQPQGVAVVVESSHL 285
[30][TOP]
>UniRef100_B2ABS9 Predicted CDS Pa_0_1000 n=1 Tax=Podospora anserina
RepID=B2ABS9_PODAN
Length = 446
Score = 136 bits (342), Expect = 1e-30
Identities = 71/166 (42%), Positives = 108/166 (65%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S ++ + ++ AV+ LL +GED +REG+ TP R AKA T+GY++NV +I+ G
Sbjct: 253 SPEQKELRMEKMKGAVRTLLECIGEDPDREGLLATPERYAKAMLFFTKGYQENVRDIVNG 312
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E G +V V+DI+++S CE L+PF K H+GYIPSN V+G+
Sbjct: 313 AIFQE-------------GHNEMVIVKDIEVFSMCEHHLVPFNGKMHIGYIPSNA-VIGI 358
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKLPR+AE FA+RLQ +RL E+ A+ E ++PQGVA++++ +H+
Sbjct: 359 SKLPRIAELFARRLQIQERLTKEVAHAIMEVLKPQGVAVVMESSHL 404
[31][TOP]
>UniRef100_B1XRI3 GTP cyclohydrolase I n=1 Tax=Synechococcus sp. PCC 7002
RepID=B1XRI3_SYNP2
Length = 212
Score = 134 bits (337), Expect = 5e-30
Identities = 73/160 (45%), Positives = 106/160 (66%)
Frame = +2
Query: 38 INRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEE 217
++ + ++ AV+ LLLGLGED +REG+R TP R+ KA T GY Q++ ++ GA+F E
Sbjct: 23 VSEAEMQAAVRTLLLGLGEDPDREGLRDTPKRLVKALKFLTSGYHQSLDELLNGAVFHE- 81
Query: 218 GLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRV 397
NTN+ +V VRDIDL+S CE +LP + HV YIP N +V+GLSK+ R+
Sbjct: 82 ---NTNE---------MVLVRDIDLFSSCEHHILPILGRAHVAYIP-NGKVIGLSKIARI 128
Query: 398 AEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +A+RLQ +RL +I ALH +QPQGVA++++ TH+
Sbjct: 129 CEMYARRLQVQERLTQQIADALHGLLQPQGVAVVVEATHM 168
[32][TOP]
>UniRef100_A8PWS4 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
7966 RepID=A8PWS4_MALGO
Length = 228
Score = 134 bits (336), Expect = 6e-30
Identities = 68/166 (40%), Positives = 106/166 (63%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S +E + N + AV+ +L LGED +R G++ TP R A+A T+GY + + ++I
Sbjct: 37 SPEEATANEDRLAGAVRTILECLGEDPDRSGLQDTPKRYARALLWMTKGYEERLCDVISN 96
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E + +V VRDID++S CE L+PF+ K H+GYIP N+ V+GL
Sbjct: 97 AIFDENHDE-------------MVIVRDIDVFSLCEHHLVPFKGKIHIGYIP-NRMVIGL 142
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE FA+RL +RL ++ LAL+E ++P+GVA++++C H+
Sbjct: 143 SKLARIAETFARRLSVQERLTRQVALALNEALKPRGVAVVMECEHM 188
[33][TOP]
>UniRef100_Q54769 GTP cyclohydrolase 1 n=2 Tax=Synechococcus elongatus
RepID=GCH1_SYNE7
Length = 213
Score = 134 bits (336), Expect = 6e-30
Identities = 71/161 (44%), Positives = 106/161 (65%)
Frame = +2
Query: 35 SINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPE 214
+++++ +E AV+ LLLG+GED REG+ KTP RVA+A+ T GY Q++ +++ GA+F E
Sbjct: 22 AVSQAEMEAAVRTLLLGVGEDPEREGLLKTPKRVAEAYRFLTSGYSQSLDDLVNGAIFDE 81
Query: 215 EGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPR 394
G +V VRDI +S CE +LPF K HV YIP NQ+VVGLSKL R
Sbjct: 82 -------------GHNEMVLVRDITAFSLCEHHMLPFMGKVHVAYIP-NQKVVGLSKLAR 127
Query: 395 VAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ E +++RLQ +RL +I ++ E + PQGVA++++ TH+
Sbjct: 128 IVEMYSRRLQVQERLTRQIAESVQEILDPQGVAVVMEATHM 168
[34][TOP]
>UniRef100_A5DIE0 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DIE0_PICGU
Length = 261
Score = 133 bits (335), Expect = 8e-30
Identities = 73/171 (42%), Positives = 113/171 (66%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRS-SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
+++ ++E S +R I AV+ +L LGED +REG+ +TP R A+A T+GY N+
Sbjct: 65 QRIEQTEEESKSRELRIAGAVRTILTELGEDPDREGLLETPERYARAMLFFTKGYEDNIR 124
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++I+ A+F E+ + +V VRDI+LYS CE L+PF K H+GYIP N+
Sbjct: 125 DVIKRAVFEEDHDE-------------MVIVRDIELYSLCEHHLVPFFGKAHIGYIP-NK 170
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE + +RLQ +RL +I +AL+E +QP+GVA++++ TH+
Sbjct: 171 RVLGLSKLARLAEMYCRRLQVQERLTKQIAMALNEMLQPRGVAVVIEATHM 221
[35][TOP]
>UniRef100_UPI00015C3BE9 GTP cyclohydrolase I n=1 Tax=Neurospora crassa OR74A
RepID=UPI00015C3BE9
Length = 182
Score = 133 bits (334), Expect = 1e-29
Identities = 70/152 (46%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL +GED +REG+ TP R AKA T+GY++NV +I+ GA+F E
Sbjct: 4 AVRTLLECIGEDPDREGLLATPERYAKAMLFLTKGYQENVRDIVNGAIFQE--------- 54
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V V+DI+++S CE L+PF K H+GYIPSN V+G+SKLPR+AE FA+RL
Sbjct: 55 ----GHNEMVIVKDIEVFSMCEHHLVPFTGKMHIGYIPSNA-VIGISKLPRIAELFARRL 109
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL E+ A+ E ++PQGVA++++ +H+
Sbjct: 110 QIQERLTKEVANAIMEILKPQGVAVVMESSHL 141
[36][TOP]
>UniRef100_B0JNJ5 GTP cyclohydrolase I n=1 Tax=Microcystis aeruginosa NIES-843
RepID=B0JNJ5_MICAN
Length = 232
Score = 133 bits (334), Expect = 1e-29
Identities = 72/166 (43%), Positives = 107/166 (64%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+SDE N+ + AV+++L+ +GED REG+ KTP RVA+A T+GY+Q++ ++ G
Sbjct: 40 TSDE---NKEQMMDAVRNILISVGEDPEREGLLKTPKRVAEAMQFLTQGYQQSLETLVNG 96
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E G +V VRDID +S CE +LPF + HV YIP NQ+VVGL
Sbjct: 97 AIFDE-------------GHNEMVLVRDIDFFSLCEHHMLPFMGRAHVAYIP-NQKVVGL 142
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I A+ E + PQGVA++++ TH+
Sbjct: 143 SKLARIVEMYSRRLQVQERLTRQIAEAIQEILDPQGVAVVMEATHM 188
[37][TOP]
>UniRef100_Q6CHC2 YALI0A10310p n=1 Tax=Yarrowia lipolytica RepID=Q6CHC2_YARLI
Length = 301
Score = 133 bits (334), Expect = 1e-29
Identities = 71/166 (42%), Positives = 106/166 (63%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+ +E I AVK +L LGED NREG+ +TP R A+A T+GY NV ++I+
Sbjct: 110 TEEEAKAREGRIADAVKTILTELGEDPNREGLLETPERYARAMLFFTKGYEDNVKDVIKR 169
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI+++S CE L+PF K H+GYIP N RV+GL
Sbjct: 170 AVFEEDHDE-------------MVIVRDIEIFSLCEHHLVPFFGKIHIGYIP-NSRVLGL 215
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE F++RLQ +RL ++ +AL E ++PQGVA++++ +H+
Sbjct: 216 SKLARLAEMFSRRLQVQERLTKQVAMALWEILEPQGVAVVIEASHM 261
[38][TOP]
>UniRef100_P51599 GTP cyclohydrolase 1 n=1 Tax=Neurospora crassa RepID=GCH1_NEUCR
Length = 313
Score = 133 bits (334), Expect = 1e-29
Identities = 70/152 (46%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL +GED +REG+ TP R AKA T+GY++NV +I+ GA+F E
Sbjct: 135 AVRTLLECIGEDPDREGLLATPERYAKAMLFLTKGYQENVRDIVNGAIFQE--------- 185
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V V+DI+++S CE L+PF K H+GYIPSN V+G+SKLPR+AE FA+RL
Sbjct: 186 ----GHNEMVIVKDIEVFSMCEHHLVPFTGKMHIGYIPSNA-VIGISKLPRIAELFARRL 240
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL E+ A+ E ++PQGVA++++ +H+
Sbjct: 241 QIQERLTKEVANAIMEILKPQGVAVVMESSHL 272
[39][TOP]
>UniRef100_C5DD81 KLTH0B09064p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DD81_LACTC
Length = 244
Score = 132 bits (333), Expect = 1e-29
Identities = 73/167 (43%), Positives = 109/167 (65%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIE 196
S +E I AVK +L LGEDV+REG+ +TP R AKA T+GY+ N++N +I+
Sbjct: 50 SPEETQQRTDRIAEAVKVILSELGEDVSREGLLETPQRYAKAMMYFTKGYQHNIINDVIK 109
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E+ + +V VRDI++YS CE L+PF K H+GYIP N++V+G
Sbjct: 110 NAVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKVHIGYIP-NKKVLG 155
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+AE +A+RLQ +RL +I +AL E ++P+GVA++++ H+
Sbjct: 156 LSKLARLAEMYARRLQVQERLTKQIAMALSEILKPRGVAVVIEAAHM 202
[40][TOP]
>UniRef100_Q94465 GTP cyclohydrolase 1 n=1 Tax=Dictyostelium discoideum
RepID=GCH1_DICDI
Length = 232
Score = 132 bits (333), Expect = 1e-29
Identities = 73/170 (42%), Positives = 109/170 (64%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E L+ + EV ++++ +VK LL LGED +REG+ KTP R++KA T+GY Q+V
Sbjct: 39 EPLIHNHEVL---NTMQSSVKTLLSSLGEDPDREGLLKTPLRMSKALLFFTQGYEQSVDE 95
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
+I A+F E + +V VRDID++S CE ++PF KCH+GYIP +Q+
Sbjct: 96 VIGEAIFNENHHE-------------MVVVRDIDIFSLCEHHMVPFHGKCHIGYIP-DQK 141
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL RVAE FA+RLQ +RL +I A+ + P GVA++++ +H+
Sbjct: 142 VLGLSKLARVAEIFARRLQVQERLTRQIAQAIQAHLNPMGVAVVIEASHM 191
[41][TOP]
>UniRef100_A8YCG2 Genome sequencing data, contig C283 n=1 Tax=Microcystis aeruginosa
PCC 7806 RepID=A8YCG2_MICAE
Length = 232
Score = 132 bits (332), Expect = 2e-29
Identities = 69/159 (43%), Positives = 103/159 (64%)
Frame = +2
Query: 41 NRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEG 220
N+ + AV+++L+ +GED REG+ KTP RVA+A T+GY+Q++ ++ GA+F E
Sbjct: 44 NKEQMMDAVRNILISVGEDPEREGLLKTPKRVAEAMQFLTQGYQQSLETLVNGAIFDE-- 101
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
G +V VRDID +S CE +LPF + HV YIP NQ+VVGLSKL R+
Sbjct: 102 -----------GHNEMVLVRDIDFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIV 149
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +++RLQ +RL +I A+ E + PQGVA++++ TH+
Sbjct: 150 EMYSRRLQVQERLTRQIAEAIQEILDPQGVAVVMEATHM 188
[42][TOP]
>UniRef100_C1MWJ7 GTP cyclohydrolase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MWJ7_9CHLO
Length = 661
Score = 132 bits (331), Expect = 2e-29
Identities = 74/185 (40%), Positives = 102/185 (55%), Gaps = 29/185 (15%)
Frame = +2
Query: 38 INRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEE 217
++ +E AV+D+L LGEDV REG+R TP RVAKA TRGY + ++ + ALF E
Sbjct: 20 VDARELERAVRDMLRALGEDVEREGLRDTPKRVAKALAFATRGYAMSAVDAVGSALFNEP 79
Query: 218 GL-----------------------------DNTNKIGHGGGVGGLVFVRDIDLYSYCES 310
GL D+ + G G+V VRDI +S E
Sbjct: 80 GLREDQEREAAAAGGFERGAEEDGGEEEDDDDDDDDDARGRSRAGVVVVRDIPFFSTSED 139
Query: 311 CLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGV 490
L+PF +CHVGY+P + +VGLSK+ RVAE FA+R+Q P RLA ++ AL G P+GV
Sbjct: 140 DLMPFYGRCHVGYVPRDGVIVGLSKVARVAEVFARRVQTPSRLARDVAEALDAGASPRGV 199
Query: 491 AIILQ 505
++ L+
Sbjct: 200 SVFLE 204
[43][TOP]
>UniRef100_C4Y0R9 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4Y0R9_CLAL4
Length = 306
Score = 131 bits (330), Expect = 3e-29
Identities = 70/164 (42%), Positives = 104/164 (63%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E I AVK +L LGEDV REG+ +TP R A+A T+GY N+ ++I+ A+
Sbjct: 117 EEAKAREQRIAGAVKTILTELGEDVTREGLLETPERYARAMMYFTKGYEDNIRDVIKRAV 176
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RVVGLSK
Sbjct: 177 FEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVVGLSK 222
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 223 LARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 266
[44][TOP]
>UniRef100_Q55759 GTP cyclohydrolase 1 n=1 Tax=Synechocystis sp. PCC 6803
RepID=GCH1_SYNY3
Length = 234
Score = 131 bits (330), Expect = 3e-29
Identities = 71/164 (43%), Positives = 103/164 (62%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+ V +N+ + AV+ +L +GED REG+ KTP RVA+A T+GY Q++ ++ GA+
Sbjct: 41 ENVELNKEKMMDAVRVMLESVGEDPEREGLLKTPKRVAEAMQFLTQGYDQSLEKLVNGAI 100
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E G +V VRDID +S CE +LPF K H+ YIP NQ+VVGLSK
Sbjct: 101 FDE-------------GHNEMVLVRDIDFFSLCEHHMLPFMGKAHLAYIP-NQKVVGLSK 146
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+ E F++RLQ +RL +I A+ E + PQGVA++++ TH+
Sbjct: 147 LARIVEMFSRRLQVQERLTRQIAEAVQEILDPQGVAVVMEATHM 190
[45][TOP]
>UniRef100_Q6BH96 DEHA2G20306p n=1 Tax=Debaryomyces hansenii RepID=Q6BH96_DEBHA
Length = 268
Score = 131 bits (329), Expect = 4e-29
Identities = 72/166 (43%), Positives = 107/166 (64%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+ +E + I AVK +L LGEDV+REG+ +TP R A+A T+GY N+ ++I+
Sbjct: 77 TQEEANGREMRIASAVKTILTELGEDVDREGLLETPERYARAMLYFTKGYEDNIRDVIKR 136
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F EE D +V VRDI++YS CE L+PF K H+ YIP N+RV+GL
Sbjct: 137 AVF-EENHDE------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGL 182
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +A+R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 183 SKLARLAEMYARRFQVQERLTKQIAMALGEILKPRGVAVVIEATHM 228
[46][TOP]
>UniRef100_C4QVZ7 GTP-cyclohydrolase I, catalyzes the first step in the folic acid
biosynthetic pathway n=1 Tax=Pichia pastoris GS115
RepID=C4QVZ7_PICPG
Length = 251
Score = 131 bits (329), Expect = 4e-29
Identities = 68/164 (41%), Positives = 106/164 (64%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E I AVK +L LGEDV REG+ +TP R A+A T+GY N+ ++I+ A+
Sbjct: 64 EEAEAREKRIASAVKTILTELGEDVEREGLLETPERYARAMLFFTKGYEDNIKDVIKRAV 123
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E+ + +V V+DID+YS CE L+PF K H+GYIP N++V+GLSK
Sbjct: 124 FEEDHDE-------------MVIVKDIDVYSLCEHHLVPFFGKVHIGYIP-NKKVLGLSK 169
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE +++R Q +RL +I +A++E ++P+GVA++++ TH+
Sbjct: 170 LARLAEMYSRRFQVQERLTKQIAMAVYEILKPRGVAVVMEATHM 213
[47][TOP]
>UniRef100_UPI0001923BE4 PREDICTED: similar to GTP cyclohydrolase 1 n=1 Tax=Hydra
magnipapillata RepID=UPI0001923BE4
Length = 239
Score = 130 bits (327), Expect = 7e-29
Identities = 67/164 (40%), Positives = 104/164 (63%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E + N S+I +V ++ G+GED NREG+ KTP R AKA T+GY +N+ +++ GA+
Sbjct: 50 EEYNSNVSNIAESVLKVIRGVGEDPNREGLLKTPERFAKAMLFFTKGYTENLQDVVNGAV 109
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E+ + LV V+DID +S CE L+ F K HVGY+P N++V+G+SK
Sbjct: 110 FNEDHDE-------------LVIVKDIDFFSMCEHHLVTFYGKVHVGYLP-NKKVIGISK 155
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ R+ E F++RLQ +RL +I LAL E + P GV ++++ H+
Sbjct: 156 IARIVEIFSRRLQVQERLTKQIALALFEAVSPSGVGVVIEACHM 199
[48][TOP]
>UniRef100_B4VSW2 GTP cyclohydrolase I n=1 Tax=Microcoleus chthonoplastes PCC 7420
RepID=B4VSW2_9CYAN
Length = 224
Score = 130 bits (327), Expect = 7e-29
Identities = 71/152 (46%), Positives = 98/152 (64%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LLLG+GED REG+ KTP RVA+A T GY Q++ ++ GA+F E
Sbjct: 43 AVRTLLLGVGEDPEREGLLKTPKRVAEAMRFLTGGYNQSLEELVNGAIFDE--------- 93
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGLSKL RV E +A+RL
Sbjct: 94 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARVVEMYARRL 148
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++PQGVA++++ TH+
Sbjct: 149 QVQERLTRQIAEAIQTILEPQGVAVVMEATHM 180
[49][TOP]
>UniRef100_Q74Z71 AGR335Cp n=1 Tax=Eremothecium gossypii RepID=Q74Z71_ASHGO
Length = 243
Score = 130 bits (327), Expect = 7e-29
Identities = 72/166 (43%), Positives = 108/166 (65%), Gaps = 1/166 (0%)
Frame = +2
Query: 23 SDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIEG 199
++E + + I AVK +L LGEDV REG+ TP R AKA T+GY+ N+LN +I
Sbjct: 50 TEEEAARAARIADAVKTILTELGEDVTREGLLDTPQRYAKAMLYFTKGYQDNILNDVINN 109
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI+++S CE L+PF K H+GYIP +RV+GL
Sbjct: 110 AVFDEDHDE-------------MVIVRDIEIHSLCEHHLVPFFGKVHIGYIP-RRRVLGL 155
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +A+RLQ +RL +I +AL + ++P+GVA++++ TH+
Sbjct: 156 SKLARLAEMYARRLQVQERLTKQIAMALQDILRPRGVAVVVEATHM 201
[50][TOP]
>UniRef100_A3LNS0 GTP cyclohydrolase I (GTP-CH-I) n=1 Tax=Pichia stipitis
RepID=A3LNS0_PICST
Length = 270
Score = 130 bits (327), Expect = 7e-29
Identities = 72/164 (43%), Positives = 106/164 (64%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E + I AVK +L LGEDV+REG+ +TP R A+A T+GY N+ ++I+ A+
Sbjct: 81 EEAEAREARIADAVKVILHELGEDVDREGLLETPERYARAMLFFTKGYEDNIRDVIKRAV 140
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F EE D +V VRDI++YS CE L+PF K H+ YIP N+RV+GLSK
Sbjct: 141 F-EENHDE------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGLSK 186
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE +A+R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 187 LARLAEMYARRFQVQERLTKQIAMALSEILRPRGVAVVIEATHM 230
[51][TOP]
>UniRef100_Q7NK98 GTP cyclohydrolase 1 n=1 Tax=Gloeobacter violaceus RepID=GCH1_GLOVI
Length = 214
Score = 130 bits (327), Expect = 7e-29
Identities = 71/152 (46%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL+G+GED R G+ +TP RVA+A T+GY Q++ ++ GA+F +
Sbjct: 34 AVRTLLVGVGEDPERNGLERTPKRVAEALKFLTKGYGQSLEELLNGAIFD---------L 84
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
GH LV VRDIDL+S CE +LPF + HVGYIP +Q+VVGLSKL R+ E +A+RL
Sbjct: 85 GHDE----LVLVRDIDLFSMCEHHMLPFIGRAHVGYIP-DQKVVGLSKLARIVEMYARRL 139
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I AL E +QP+GVA++++ +H+
Sbjct: 140 QVQERLTRQIAEALQEVLQPRGVAVVIEASHM 171
[52][TOP]
>UniRef100_Q5AK63 Putative uncharacterized protein FOL2 n=1 Tax=Candida albicans
RepID=Q5AK63_CANAL
Length = 276
Score = 130 bits (326), Expect = 9e-29
Identities = 69/166 (41%), Positives = 106/166 (63%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+S+E I AVK +L LGED +REG+ +TP R A+A T+GY N+ ++I+
Sbjct: 89 TSEEAKAREERIASAVKVILEELGEDTSREGLLETPERYARAMLYFTKGYEDNIRDVIKR 148
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RV+GL
Sbjct: 149 AVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGL 194
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 195 SKLARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 240
[53][TOP]
>UniRef100_C4YRY1 GTP cyclohydrolase I n=1 Tax=Candida albicans RepID=C4YRY1_CANAL
Length = 280
Score = 130 bits (326), Expect = 9e-29
Identities = 69/166 (41%), Positives = 106/166 (63%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+S+E I AVK +L LGED +REG+ +TP R A+A T+GY N+ ++I+
Sbjct: 89 TSEEAKAREERIASAVKVILEELGEDTSREGLLETPERYARAMLYFTKGYEDNIRDVIKR 148
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RV+GL
Sbjct: 149 AVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGL 194
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 195 SKLARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 240
[54][TOP]
>UniRef100_B9WI16 GTP cyclohydrolase I, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WI16_CANDC
Length = 280
Score = 130 bits (326), Expect = 9e-29
Identities = 69/166 (41%), Positives = 106/166 (63%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+S+E I AVK +L LGED +REG+ +TP R A+A T+GY N+ ++I+
Sbjct: 89 TSEEAKAREERIASAVKVILEELGEDTSREGLLETPERYARAMLYFTKGYEDNIRDVIKR 148
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RV+GL
Sbjct: 149 AVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGL 194
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 195 SKLARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 240
[55][TOP]
>UniRef100_B1WXA7 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. ATCC 51142
RepID=B1WXA7_CYAA5
Length = 212
Score = 129 bits (325), Expect = 1e-28
Identities = 73/169 (43%), Positives = 105/169 (62%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
+LVSS + + AV+ LLLGLGED +REG+R TP RV KA T GY Q++ +
Sbjct: 13 RLVSSSHPPVTEEEMRQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYHQSLDEL 72
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E NT++ +V VRDIDL+S CE +LP + HV YIP +V
Sbjct: 73 LNGAVFHE----NTDE---------MVLVRDIDLFSSCEHHILPILGRAHVAYIPDG-KV 118
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSK+ R+ E + +RLQ +RL +I AL +QP+GVA++++ TH+
Sbjct: 119 IGLSKIARICEMYGRRLQVQERLTAQIADALQGLLQPKGVAVVVEATHM 167
[56][TOP]
>UniRef100_C8V749 Putative uncharacterized protein n=1 Tax=Aspergillus nidulans FGSC
A4 RepID=C8V749_EMENI
Length = 329
Score = 129 bits (325), Expect = 1e-28
Identities = 66/152 (43%), Positives = 104/152 (68%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L LGED +REG+R+TP R AKA T+GY +NV +++ GA+F E+ +
Sbjct: 152 AVRTILECLGEDPDREGLRETPDRYAKAMLYFTKGYEENVRDLVNGAVFHEDHDE----- 206
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DID++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 207 --------LVIVKDIDVFSLCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 257
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E ++P+GV ++++ +H+
Sbjct: 258 QVQERLTKQVALAISEVLKPRGVGVVMESSHL 289
[57][TOP]
>UniRef100_A4QU95 GTP cyclohydrolase I, putative n=1 Tax=Magnaporthe grisea
RepID=A4QU95_MAGGR
Length = 310
Score = 129 bits (325), Expect = 1e-28
Identities = 67/152 (44%), Positives = 101/152 (66%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL +GED +R+G+ TP R AKA T+GY++N+ +I+ A+F E
Sbjct: 131 AVRTLLECVGEDPDRQGLLATPDRYAKALLFLTKGYQENIKDIVNNAIFHE--------- 181
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V V+DI+++S CE L+PF K H+GYIP+N V+GLSKLPR+AE FA+RL
Sbjct: 182 ----GHNEMVIVKDIEIFSMCEHHLVPFTGKMHIGYIPANS-VIGLSKLPRIAELFARRL 236
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL E+ A+ E ++PQGVA++++ +H+
Sbjct: 237 QIQERLTKEVANAIFEVLKPQGVAVVMESSHL 268
[58][TOP]
>UniRef100_A2QUD9 Function: catalyzes synthesis of D-erythro-7 n=1 Tax=Aspergillus
niger CBS 513.88 RepID=A2QUD9_ASPNC
Length = 315
Score = 129 bits (325), Expect = 1e-28
Identities = 70/171 (40%), Positives = 112/171 (65%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L SS E + R + AV+ +L +GED REG+R+TP R AKA T+GY +NV
Sbjct: 119 ERLESSPEETEERIKKLAGAVRTILECVGEDPEREGLRETPERYAKAMLYFTKGYEENVR 178
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 179 DLVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DR 224
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL ++ LA+ E ++P+GV ++++ +H+
Sbjct: 225 RVLGLSKLARLAEMFSRRLQVQERLTKQVALAISEVLKPRGVGVVMESSHL 275
[59][TOP]
>UniRef100_Q2UA70 GTP cyclohydrolase I n=1 Tax=Aspergillus oryzae RepID=Q2UA70_ASPOR
Length = 278
Score = 129 bits (324), Expect = 2e-28
Identities = 70/170 (41%), Positives = 110/170 (64%), Gaps = 1/170 (0%)
Frame = +2
Query: 11 KLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
+L SS E + R + AV+ +L +GED REG+R+TP R AKA T+GY +NV +
Sbjct: 83 RLESSPEETEERVQKLAGAVRTILECIGEDPEREGLRETPERYAKAMLYFTKGYEENVRD 142
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP N+R
Sbjct: 143 LVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFMGKMHIGYIP-NRR 188
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+AE F++RLQ +RL ++ LA+ E ++P GV ++++ +H+
Sbjct: 189 VLGLSKLARLAEMFSRRLQVQERLTKQVALAISEVLKPLGVGVVMESSHL 238
[60][TOP]
>UniRef100_B8NRB2 GTP cyclohydrolase I, putative n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8NRB2_ASPFN
Length = 331
Score = 129 bits (324), Expect = 2e-28
Identities = 70/170 (41%), Positives = 110/170 (64%), Gaps = 1/170 (0%)
Frame = +2
Query: 11 KLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
+L SS E + R + AV+ +L +GED REG+R+TP R AKA T+GY +NV +
Sbjct: 136 RLESSPEETEERVQKLAGAVRTILECIGEDPEREGLRETPERYAKAMLYFTKGYEENVRD 195
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP N+R
Sbjct: 196 LVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFMGKMHIGYIP-NRR 241
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+AE F++RLQ +RL ++ LA+ E ++P GV ++++ +H+
Sbjct: 242 VLGLSKLARLAEMFSRRLQVQERLTKQVALAISEVLKPLGVGVVMESSHL 291
[61][TOP]
>UniRef100_A5E346 GTP cyclohydrolase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E346_LODEL
Length = 307
Score = 129 bits (324), Expect = 2e-28
Identities = 69/164 (42%), Positives = 106/164 (64%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E S I AVK +L LGED +REG+ +TP R A+A T+GY +N+ ++I+ A+
Sbjct: 118 EEASQREKRISDAVKIILEELGEDTSREGLVETPERYARAMLYFTKGYEENIRDVIKRAV 177
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RV+GLSK
Sbjct: 178 FEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGLSK 223
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 224 LARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 267
[62][TOP]
>UniRef100_P51601 GTP cyclohydrolase 1 n=6 Tax=Saccharomyces cerevisiae
RepID=GCH1_YEAST
Length = 243
Score = 129 bits (324), Expect = 2e-28
Identities = 69/156 (44%), Positives = 105/156 (67%), Gaps = 1/156 (0%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIEGALFPEEGLDN 229
I A+K +L LGEDVNREG+ TP R AKA T+GY+ N+++ +I+ A+F E+ +
Sbjct: 61 ISGAIKTILTELGEDVNREGLLDTPQRYAKAMLYFTKGYQTNIMDDVIKNAVFEEDHDE- 119
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V VRDI++YS CE L+PF K H+GYIP N++V+GLSKL R+AE +
Sbjct: 120 ------------MVIVRDIEIYSLCEHHLVPFFGKVHIGYIP-NKKVIGLSKLARLAEMY 166
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ +RL +I +AL + ++P GVA++++ +H+
Sbjct: 167 ARRLQVQERLTKQIAMALSDILKPLGVAVVMEASHM 202
[63][TOP]
>UniRef100_B0JGA3 GTP cyclohydrolase I n=1 Tax=Microcystis aeruginosa NIES-843
RepID=B0JGA3_MICAN
Length = 218
Score = 129 bits (323), Expect = 2e-28
Identities = 70/169 (41%), Positives = 109/169 (64%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
++++ + ++ + + AV+ LLLGLGED +REG+R TP RV KA T GY+Q++ +
Sbjct: 20 EVITEPKSPVSEAEMMQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYQQSLDEL 79
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E N N+ +V +RDID++S CE +LP + HV YIP N +V
Sbjct: 80 LNGAVFHE----NANE---------MVLIRDIDIFSSCEHHILPIIGRAHVAYIP-NGKV 125
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSK+ R+ E +A+RLQ +RL +I AL +QPQGVA++++ TH+
Sbjct: 126 IGLSKIARICEMYARRLQVQERLTAQIADALQGLLQPQGVAVVIEATHM 174
[64][TOP]
>UniRef100_B7KE49 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. PCC 7424
RepID=B7KE49_CYAP7
Length = 247
Score = 128 bits (322), Expect = 3e-28
Identities = 70/159 (44%), Positives = 99/159 (62%)
Frame = +2
Query: 41 NRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEG 220
N+ + AV+ +L +GED REG+ KTP RVA+A T+GY Q++ ++ A+F E
Sbjct: 59 NKEKMMQAVEMILESVGEDPGREGLLKTPKRVAEAMQFLTQGYNQSLEELVNDAIFDE-- 116
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
G +V VRDID +S CE +LPF K HV YIP NQ+VVGLSKL R+
Sbjct: 117 -----------GHNEMVLVRDIDFFSLCEHHMLPFMGKAHVAYIP-NQKVVGLSKLARIV 164
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +A+RLQ +RL +I A+ E + PQGVA++++ TH+
Sbjct: 165 EMYARRLQVQERLTRQIAEAIQEILNPQGVAVVMEATHM 203
[65][TOP]
>UniRef100_C1ZU49 GTP cyclohydrolase I n=1 Tax=Rhodothermus marinus DSM 4252
RepID=C1ZU49_RHOMR
Length = 210
Score = 128 bits (322), Expect = 3e-28
Identities = 71/167 (42%), Positives = 104/167 (62%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+I+ V+++L +GED +REG+R+TP RVA A T+GY Q+ I+E ALF E+ +
Sbjct: 30 AIQQHVREILRWIGEDPDREGLRRTPERVALALQYLTQGYHQDPRAILEAALFEEDYSE- 88
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
++ VRDI +YS CE LLPF K HV YIP N+++VGLSK+PRV + F
Sbjct: 89 ------------MILVRDIQIYSLCEHHLLPFFGKAHVAYIP-NKKIVGLSKIPRVVDVF 135
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
A+RLQ +RL +I AL E +QP GVA++++ H+ + + H
Sbjct: 136 ARRLQVQERLTIQIRDALEEVLQPLGVAVVIEAQHLCMMMRGVEKQH 182
[66][TOP]
>UniRef100_C5MJ32 GTP cyclohydrolase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5MJ32_CANTT
Length = 281
Score = 128 bits (322), Expect = 3e-28
Identities = 69/166 (41%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S +E I AVK +L LGED REG+ +TP R A+A T+GY N+ ++I+
Sbjct: 90 SPEEAKAREERIADAVKVILEELGEDTTREGLLETPERYARAMLYFTKGYEDNIRDVIKR 149
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V VRDI++YS CE L+PF K H+ YIP N+RV+GL
Sbjct: 150 AVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKAHIAYIP-NKRVLGL 195
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+AE +++R Q +RL +I +AL E ++P+GVA++++ TH+
Sbjct: 196 SKLARLAEMYSRRFQVQERLTKQIAMALSEILKPRGVAVVIEATHM 241
[67][TOP]
>UniRef100_B6HKY8 Pc21g16300 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6HKY8_PENCW
Length = 341
Score = 128 bits (322), Expect = 3e-28
Identities = 64/152 (42%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A++ +L +GED REG+R+TP R AKA T+GY +NV +++ A+F E+ +
Sbjct: 164 AIRTILECIGEDPEREGLRETPLRYAKAMLYFTKGYEENVRDLVNNAVFHEDHDE----- 218
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DID++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 219 --------LVIVKDIDVFSMCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 269
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E +QP+GV ++++ +H+
Sbjct: 270 QVQERLTKQVALAISEVLQPRGVGVVMESSHL 301
[68][TOP]
>UniRef100_Q72LY8 GTP cyclohydrolase 1 n=2 Tax=Leptospira interrogans
RepID=GCH1_LEPIC
Length = 183
Score = 128 bits (322), Expect = 3e-28
Identities = 65/155 (41%), Positives = 97/155 (62%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E V ++L +GED REG+ TP RV KA+ T GYR ++ I+ GA+F E
Sbjct: 1 MEEDVINILKSIGEDPTREGLLNTPKRVKKAYEFLTSGYRADITKIVNGAIFEEP----- 55
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
G+V VRDI++YS CE LLPF K HV Y+P N++++G+SK+PR+ + FA
Sbjct: 56 --------TEGMVLVRDIEMYSLCEHHLLPFYGKAHVAYLP-NKKIIGISKIPRIVDVFA 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I A+ E + PQGVA++++ H+
Sbjct: 107 RRLQVQERLTEQIAYAIQEVLDPQGVAVVIKAKHL 141
[69][TOP]
>UniRef100_A8ZL68 GTP cyclohydrolase I n=1 Tax=Acaryochloris marina MBIC11017
RepID=A8ZL68_ACAM1
Length = 210
Score = 128 bits (321), Expect = 4e-28
Identities = 72/171 (42%), Positives = 108/171 (63%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
V L + + ++ + ++ AV+ LLLGLGED +REG+R TP R+ KA T GY+Q++
Sbjct: 10 VPALTTEAQPIVSEAEMQAAVRTLLLGLGEDPDREGLRDTPKRMVKALKFLTSGYQQSLD 69
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++ GA+FPE+ LD +V VRDIDL+S CE + P K HV YIP N
Sbjct: 70 ELLNGAIFPED-LDE------------MVLVRDIDLFSSCEHHIWPIIGKVHVAYIP-NG 115
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ R+ E +A+RLQ +RL +I AL + PQGVA++++ +H+
Sbjct: 116 KVIGLSKIARICEMYARRLQVQERLTAQIADALQGLLNPQGVAVVVEASHM 166
[70][TOP]
>UniRef100_C7QKY2 GTP cyclohydrolase I n=2 Tax=Cyanothece RepID=C7QKY2_CYAP0
Length = 214
Score = 128 bits (321), Expect = 4e-28
Identities = 70/169 (41%), Positives = 105/169 (62%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
KL++ + + + AV+ LLLGLGED +REG+R TP RV KA T GY Q++ +
Sbjct: 15 KLITQSQPPVTEEEMRQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYHQSLDEL 74
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E NT++ +V VRDIDL+S CE +LP + H+ YIP +V
Sbjct: 75 LNGAVFHE----NTDE---------MVLVRDIDLFSSCEHHILPILGRAHIAYIPDG-KV 120
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSK+ R+ E + +RLQ +RL +I AL +QP+GVA++++ TH+
Sbjct: 121 IGLSKIARICEMYGRRLQVQERLTAQIADALQGLLQPKGVAVVVEATHM 169
[71][TOP]
>UniRef100_C5JFH9 GTP cyclohydrolase I n=1 Tax=Ajellomyces dermatitidis SLH14081
RepID=C5JFH9_AJEDS
Length = 392
Score = 128 bits (321), Expect = 4e-28
Identities = 70/171 (40%), Positives = 112/171 (65%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L ++ E S R+ + AV+ +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 196 ERLEATPEESEKRTQKLADAVRTILECIGEDPQREGLLGTPERYAKALMYFTKGYEENVR 255
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 256 DLVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DR 301
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL ++ LA+ E ++PQGVA++++ +H+
Sbjct: 302 RVLGLSKLARLAEMFSRRLQVQERLTKQVALAIAEVLKPQGVAVVMESSHL 352
[72][TOP]
>UniRef100_C5GI46 GTP cyclohydrolase I n=1 Tax=Ajellomyces dermatitidis ER-3
RepID=C5GI46_AJEDR
Length = 312
Score = 128 bits (321), Expect = 4e-28
Identities = 70/171 (40%), Positives = 112/171 (65%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L ++ E S R+ + AV+ +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 116 ERLEATPEESEKRTQKLADAVRTILECIGEDPQREGLLGTPERYAKALMYFTKGYEENVR 175
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 176 DLVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DR 221
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL ++ LA+ E ++PQGVA++++ +H+
Sbjct: 222 RVLGLSKLARLAEMFSRRLQVQERLTKQVALAIAEVLKPQGVAVVMESSHL 272
[73][TOP]
>UniRef100_B6HE33 Pc20g04620 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6HE33_PENCW
Length = 301
Score = 128 bits (321), Expect = 4e-28
Identities = 68/171 (39%), Positives = 104/171 (60%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
++KL S + + AV +L +GE+ REG+R TP R A A T+GY ++V
Sbjct: 105 IQKLESPQGENRGVQKLARAVCTILECIGEEPTREGLRATPERYANAMLYFTKGYAESVH 164
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E G LV +RDID++S CE L+PF K H+GYIP N
Sbjct: 165 DLVNGAVFHE-------------GHDELVILRDIDVFSLCEHHLVPFTGKVHIGYIPDN- 210
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
R++GLSKL + E FA+RLQ +RL ++ LA+ E + P+GVA++++C+H+
Sbjct: 211 RILGLSKLAHLVEMFARRLQVQERLTKQVALAISEALNPRGVAVVMECSHL 261
[74][TOP]
>UniRef100_B7KJE3 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. PCC 7424
RepID=B7KJE3_CYAP7
Length = 218
Score = 127 bits (320), Expect = 5e-28
Identities = 72/168 (42%), Positives = 106/168 (63%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L + ++ + + AV+ LLLGLGED +REG+R TP RV KA T GY Q++ ++
Sbjct: 21 LTTEHHSPVSEADMIQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYHQSLDELL 80
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
GA+F E+ TN+ +V VRDIDL+S CE +LP + HV YIP N +V+
Sbjct: 81 NGAVFGED----TNE---------MVLVRDIDLFSSCEHHILPILGRAHVAYIP-NGKVI 126
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
GLSK+ R+ E +A+RLQ +RL +I AL ++PQGVA++++ TH+
Sbjct: 127 GLSKIARICEMYARRLQVQERLTAQIADALQGLLKPQGVAVVIEATHM 174
[75][TOP]
>UniRef100_Q6CXB4 KLLA0A09735p n=1 Tax=Kluyveromyces lactis RepID=Q6CXB4_KLULA
Length = 245
Score = 127 bits (320), Expect = 5e-28
Identities = 72/172 (41%), Positives = 109/172 (63%), Gaps = 2/172 (1%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+ +DE R I AVK +L LGED REG+ TP R AKA T+GY+ N++
Sbjct: 47 ERAEETDEEEQKRVGRIADAVKTILSELGEDTEREGLLDTPTRYAKAMLYFTKGYQDNIM 106
Query: 185 N-IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
N +I+ A+F E+ + +V VRDI+++S CE L+PF K H+GYIP N
Sbjct: 107 NDVIKNAVFEEDHDE-------------MVIVRDIEIFSLCEHHLVPFFGKVHIGYIP-N 152
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++V+GLSKL R+AE +A+R Q +RL +I +AL + ++P+GVA++++ TH+
Sbjct: 153 KKVLGLSKLARLAEMYARRFQVQERLTKQIAMALSDILKPRGVAVVIEATHM 204
[76][TOP]
>UniRef100_O61573 GTP cyclohydrolase 1 n=1 Tax=Ostertagia ostertagi RepID=GCH1_OSTOS
Length = 213
Score = 127 bits (320), Expect = 5e-28
Identities = 65/170 (38%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
+K+++ + + N + A ++ +GEDVNR+G+ KTP R AKA T+GY Q + +
Sbjct: 19 QKIIAFSKKTSNLDKMTAAYSSIISHVGEDVNRQGLLKTPDRAAKAMLYFTKGYEQQLDD 78
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
I+ A+F E + +V VRDI+++S CE L+PF K H+GYIP N++
Sbjct: 79 ILNDAVFDENHDE-------------MVIVRDIEMFSLCEHHLVPFNGKVHIGYIP-NKK 124
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E F++RLQ +RL +I A+ + +QP GVA++++ +H+
Sbjct: 125 VLGLSKLARIVEMFSRRLQVQERLTKQIATAMVQAVQPAGVAVVIEASHM 174
[77][TOP]
>UniRef100_B0S8X8 GTP cyclohydrolase 1 n=2 Tax=Leptospira biflexa serovar Patoc
RepID=GCH1_LEPBA
Length = 183
Score = 127 bits (320), Expect = 5e-28
Identities = 64/155 (41%), Positives = 101/155 (65%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E ++++L +GED NREG+ KTP RV KA+ T GY+ ++ ++ GA+F E NT
Sbjct: 1 MENLIEEILKQIGEDPNREGLVKTPNRVKKAYDFLTSGYKADINQLVNGAIFEE----NT 56
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
G+V VRDI++YS CE LLPF + HV YIP N++++G+SK+PR+ + FA
Sbjct: 57 T---------GMVLVRDIEMYSLCEHHLLPFYGRAHVAYIP-NKKIIGISKIPRIVDVFA 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL ++I A+ E + P GV ++++ H+
Sbjct: 107 RRLQVQERLTDQIAQAIQETLDPLGVGVVIKAKHL 141
[78][TOP]
>UniRef100_B0CDI3 GTP cyclohydrolase I n=1 Tax=Acaryochloris marina MBIC11017
RepID=B0CDI3_ACAM1
Length = 211
Score = 127 bits (319), Expect = 6e-28
Identities = 71/170 (41%), Positives = 109/170 (64%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E L + + ++ + +E AV+ LLLG+GED +REG+R TP RV K+ + GY+Q++
Sbjct: 12 ETLTTEAQPIVSEAEMEAAVRTLLLGMGEDPDREGLRDTPKRVVKSLKFLSSGYQQSLDE 71
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ GA+F E+ LD +V VRDIDL+S CE +LP K HV YIP N +
Sbjct: 72 LLNGAVFSED-LDE------------MVLVRDIDLFSSCEHHILPIIGKAHVAYIP-NGK 117
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSK+ R+ E +A+RLQ +RL +I AL ++PQGVA++++ +H+
Sbjct: 118 VIGLSKIARICEMYARRLQVQERLTAQIADALQGLLKPQGVAVVVEASHM 167
[79][TOP]
>UniRef100_A3IH31 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. CCY0110
RepID=A3IH31_9CHRO
Length = 216
Score = 127 bits (319), Expect = 6e-28
Identities = 71/169 (42%), Positives = 104/169 (61%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
+L+S + + AV+ LLLGLGED +REG+R TP RV KA T GY Q++ +
Sbjct: 17 RLISRSHPPVTEEEMHQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYHQSLDEL 76
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E NT++ +V VRDIDL+S CE +LP + HV YIP +V
Sbjct: 77 LNGAVFHE----NTDE---------MVLVRDIDLFSSCEHHILPILGRAHVAYIPDG-KV 122
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSK+ R+ E + +RLQ +RL +I AL +QP+GVA++++ TH+
Sbjct: 123 IGLSKIARICEMYGRRLQVQERLTAQIADALQGLLQPKGVAVVVEATHM 171
[80][TOP]
>UniRef100_C5DVK7 ZYRO0D07480p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DVK7_ZYGRC
Length = 243
Score = 127 bits (319), Expect = 6e-28
Identities = 70/156 (44%), Positives = 103/156 (66%), Gaps = 1/156 (0%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIEGALFPEEGLDN 229
I AVK +L LGEDV REG+ TP R AKA T+GY+ N+++ +I+ A+F E+ +
Sbjct: 61 ISGAVKTILEELGEDVTREGLADTPQRYAKAMLFFTKGYQTNIMDDVIKNAVFEEDHDE- 119
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V VRDI++YS CE L+PF K H+GYIP N+RV+GLSKL R+AE +
Sbjct: 120 ------------MVIVRDIEIYSLCEHHLVPFFGKVHIGYIP-NKRVLGLSKLARLAEMY 166
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I +AL + ++P GVA++++ TH+
Sbjct: 167 CRRLQVQERLTKQIAMALGDILKPMGVAVVIEATHM 202
[81][TOP]
>UniRef100_B1XK67 GTP cyclohydrolase I n=1 Tax=Synechococcus sp. PCC 7002
RepID=B1XK67_SYNP2
Length = 239
Score = 127 bits (318), Expect = 8e-28
Identities = 69/152 (45%), Positives = 97/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV +L +GED +REG+ KTP RVAKA T+GY Q++ +I+ GA+F E
Sbjct: 58 AVHTMLEAVGEDPDREGLLKTPLRVAKAMQFLTQGYNQSLEDIVNGAIFDE--------- 108
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDID +S CE +LPF + HV YIP NQ+VVGLSKL R+ E +++RL
Sbjct: 109 ----GHNEMVLVRDIDFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIVEMYSRRL 163
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ E + PQGVA++++ H+
Sbjct: 164 QVQERLTRQIAEAVQEILDPQGVAVVMEGIHM 195
[82][TOP]
>UniRef100_B4W132 GTP cyclohydrolase I n=1 Tax=Microcoleus chthonoplastes PCC 7420
RepID=B4W132_9CYAN
Length = 207
Score = 127 bits (318), Expect = 8e-28
Identities = 69/168 (41%), Positives = 106/168 (63%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L +SD+ ++ + AV+ LLLGLGE+ +REG++ TP RV KA T GY Q++ ++
Sbjct: 10 LSTSDKPLVSDEEMRQAVRTLLLGLGENPDREGLQDTPKRVVKALKFLTSGYHQSLDELL 69
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
GA+F E+ + +V VRDID++S CE +LP + HV YIP N +V+
Sbjct: 70 NGAVFTEDANE-------------MVLVRDIDIFSSCEHHILPILGRAHVAYIP-NGKVI 115
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
GLSK+ R+ E + +RLQ +RL +I AL E ++PQGVA++++ TH+
Sbjct: 116 GLSKIARICEMYGRRLQVQERLTAQIADALTELLKPQGVAVVVEATHL 163
[83][TOP]
>UniRef100_A8YDV7 FolE2 protein n=1 Tax=Microcystis aeruginosa PCC 7806
RepID=A8YDV7_MICAE
Length = 218
Score = 127 bits (318), Expect = 8e-28
Identities = 67/169 (39%), Positives = 107/169 (63%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
++++ + ++ + A++ LLLGLGED +REG+R TP RV KA T GY+Q++ +
Sbjct: 20 EVITEPKSPVSEFEMMQAIRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYQQSLDEL 79
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
+ GA+F E+ + +V +RDID++S CE +LP + HV YIP N +V
Sbjct: 80 LNGAVFHEDANE-------------MVLIRDIDIFSSCEHHILPIIGRAHVAYIP-NGKV 125
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+GLSK+ R+ E +A+RLQ +RL +I AL +QPQGVA++++ TH+
Sbjct: 126 IGLSKIARICEMYARRLQVQERLTAQIADALQGLLQPQGVAVVIEATHM 174
[84][TOP]
>UniRef100_Q2Q448 GTP cyclohydrolase I n=1 Tax=Toxoplasma gondii RepID=Q2Q448_TOXGO
Length = 262
Score = 127 bits (318), Expect = 8e-28
Identities = 70/159 (44%), Positives = 106/159 (66%), Gaps = 1/159 (0%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP-EEG 220
+++IE V+ +L +GEDV R G+R+TP RVA A +RGYR + ++I ALF EEG
Sbjct: 63 KNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALFSVEEG 122
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
++ + G G+V V ID+ S CE LLPF KCH+GYIP ++ V+G+SK R+
Sbjct: 123 HEDGQYLA---GKQGMVTVGRIDISSLCEHHLLPFFGKCHIGYIP-DKHVLGISKFARIM 178
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +++RLQ +RL +I LA+ + +P+GVA++L+CTH+
Sbjct: 179 EIYSRRLQIQERLTQQIALAVMKVAKPRGVAVLLECTHM 217
[85][TOP]
>UniRef100_B9QJ00 GTP cyclohydrolase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9QJ00_TOXGO
Length = 563
Score = 127 bits (318), Expect = 8e-28
Identities = 70/159 (44%), Positives = 106/159 (66%), Gaps = 1/159 (0%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP-EEG 220
+++IE V+ +L +GEDV R G+R+TP RVA A +RGYR + ++I ALF EEG
Sbjct: 364 KNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALFSVEEG 423
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
++ + G G+V V ID+ S CE LLPF KCH+GYIP ++ V+G+SK R+
Sbjct: 424 HEDGQYLA---GKQGMVTVGRIDISSLCEHHLLPFFGKCHIGYIP-DKHVLGISKFARIM 479
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +++RLQ +RL +I LA+ + +P+GVA++L+CTH+
Sbjct: 480 EIYSRRLQIQERLTQQIALAVMKVAKPRGVAVLLECTHM 518
[86][TOP]
>UniRef100_B9PWR5 GTP cyclohydrolase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWR5_TOXGO
Length = 563
Score = 127 bits (318), Expect = 8e-28
Identities = 70/159 (44%), Positives = 106/159 (66%), Gaps = 1/159 (0%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP-EEG 220
+++IE V+ +L +GEDV R G+R+TP RVA A +RGYR + ++I ALF EEG
Sbjct: 364 KNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALFSVEEG 423
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
++ + G G+V V ID+ S CE LLPF KCH+GYIP ++ V+G+SK R+
Sbjct: 424 HEDGQYLA---GKQGMVTVGRIDISSLCEHHLLPFFGKCHIGYIP-DKHVLGISKFARIM 479
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +++RLQ +RL +I LA+ + +P+GVA++L+CTH+
Sbjct: 480 EIYSRRLQIQERLTQQIALAVMKVAKPRGVAVLLECTHM 518
[87][TOP]
>UniRef100_B6KNL1 GTP cyclohydrolase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KNL1_TOXGO
Length = 563
Score = 127 bits (318), Expect = 8e-28
Identities = 70/159 (44%), Positives = 106/159 (66%), Gaps = 1/159 (0%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP-EEG 220
+++IE V+ +L +GEDV R G+R+TP RVA A +RGYR + ++I ALF EEG
Sbjct: 364 KNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALFSVEEG 423
Query: 221 LDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVA 400
++ + G G+V V ID+ S CE LLPF KCH+GYIP ++ V+G+SK R+
Sbjct: 424 HEDGQYLA---GKQGMVTVGRIDISSLCEHHLLPFFGKCHIGYIP-DKHVLGISKFARIM 479
Query: 401 EAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +++RLQ +RL +I LA+ + +P+GVA++L+CTH+
Sbjct: 480 EIYSRRLQIQERLTQQIALAVMKVAKPRGVAVLLECTHM 518
[88][TOP]
>UniRef100_C7YV22 Putative uncharacterized protein n=1 Tax=Nectria haematococca mpVI
77-13-4 RepID=C7YV22_NECH7
Length = 312
Score = 127 bits (318), Expect = 8e-28
Identities = 69/152 (45%), Positives = 99/152 (65%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL +GED +REG+ TP R AKA T+GY+ N +I+ ALF E
Sbjct: 134 AVRTLLECVGEDPDREGLLDTPSRYAKALLFLTQGYQVNAEDIVNNALFRE--------- 184
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V V+DI+++S CE L+PF K H+GYIP N+ V+GLSKLPR+AE FA+RL
Sbjct: 185 ----GHSEMVVVKDIEVFSLCEHHLVPFTGKMHIGYIP-NETVIGLSKLPRIAEMFARRL 239
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL E+ A+ E ++PQGVA++++ +H+
Sbjct: 240 QIQERLTKEVANAIMEILKPQGVAVVMESSHL 271
[89][TOP]
>UniRef100_A7EWA1 GTP cyclohydrolase n=1 Tax=Sclerotinia sclerotiorum 1980 UF-70
RepID=A7EWA1_SCLS1
Length = 303
Score = 127 bits (318), Expect = 8e-28
Identities = 64/166 (38%), Positives = 109/166 (65%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S ++ ++ S + AV+ +L +GED +REG+ TP R AKA T+GY++NV +I+
Sbjct: 110 SPEQAAVRMSKLTGAVRTILECIGEDPDREGLLATPERYAKAMLYLTKGYQENVRDIVND 169
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++ V+G+
Sbjct: 170 AIFHEDHNE-------------LVIVKDIEVFSMCEHHMVPFTGKMHIGYIP-DRNVIGI 215
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKLPR+A+ F++RLQ +RL ++ A+ E ++PQGVA++++ +H+
Sbjct: 216 SKLPRIADMFSRRLQIQERLTKDVAHAVMEILKPQGVAVVMESSHL 261
[90][TOP]
>UniRef100_Q90WT2 GTP cyclohydrolase I n=1 Tax=Danio rerio RepID=Q90WT2_DANRE
Length = 240
Score = 126 bits (317), Expect = 1e-27
Identities = 64/156 (41%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L GLGE+ +R+G+ KTP R AKA T+GY + + +I+ A+F E+ +
Sbjct: 58 ALEAAYTTILRGLGENTDRQGLLKTPLRAAKAMQFLTKGYHETIYDILNDAIFDEDHEE- 116
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
LV V+DID++S CE L+PF K H+GY+PS ++VVGLSKL R+ E +
Sbjct: 117 ------------LVIVKDIDMFSLCEHHLVPFFGKVHIGYLPS-KKVVGLSKLARIVEIY 163
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I +A+ E +QP GVA++++ H+
Sbjct: 164 SRRLQVQERLTKQIAMAISEALQPVGVAVVIEAAHM 199
[91][TOP]
>UniRef100_Q6IQV5 GTP cyclohydrolase 2 n=1 Tax=Danio rerio RepID=Q6IQV5_DANRE
Length = 240
Score = 126 bits (317), Expect = 1e-27
Identities = 64/156 (41%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L GLGE+ +R+G+ KTP R AKA T+GY + + +I+ A+F E+ +
Sbjct: 58 ALEAAYTTILRGLGENTDRQGLLKTPLRAAKAMQFLTKGYHETIYDILNDAIFDEDHEE- 116
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
LV V+DID++S CE L+PF K H+GY+PS ++VVGLSKL R+ E +
Sbjct: 117 ------------LVIVKDIDMFSLCEHHLVPFFGKVHIGYLPS-KKVVGLSKLARIVEIY 163
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I +A+ E +QP GVA++++ H+
Sbjct: 164 SRRLQVQERLTKQIAMAISEALQPVGVAVVIEAAHM 199
[92][TOP]
>UniRef100_Q3UC70 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q3UC70_MOUSE
Length = 241
Score = 126 bits (317), Expect = 1e-27
Identities = 62/166 (37%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S +E +N + A +LL LGED R+G+ KTP+R A A T+GY++ + +++
Sbjct: 51 SEEENQVNLPKLAAAYSSILLSLGEDPQRQGLLKTPWRAATAMQYFTKGYQETISDVLND 110
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V V+DID++S CE L+PF + H+GY+P N++V+GL
Sbjct: 111 AIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGRVHIGYLP-NKQVLGL 156
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 157 SKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHM 202
[93][TOP]
>UniRef100_Q0CDY3 GTP cyclohydrolase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CDY3_ASPTN
Length = 333
Score = 126 bits (317), Expect = 1e-27
Identities = 69/170 (40%), Positives = 110/170 (64%), Gaps = 1/170 (0%)
Frame = +2
Query: 11 KLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
+L SS E + R + AV+ +L +GED REG+R+TP R AKA T+GY +NV +
Sbjct: 138 RLESSPEQTEERIQKLAGAVRTILECVGEDPEREGLRETPERYAKAMLYFTKGYEENVRD 197
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++R
Sbjct: 198 LVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DRR 243
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+AE F++RLQ +RL ++ LA+ E ++P GV ++++ +H+
Sbjct: 244 VLGLSKLARLAEMFSRRLQVQERLTKQVALAISEVLKPLGVGVVMESSHL 293
[94][TOP]
>UniRef100_Q05915 GTP cyclohydrolase 1 n=2 Tax=Mus musculus RepID=GCH1_MOUSE
Length = 241
Score = 126 bits (317), Expect = 1e-27
Identities = 62/166 (37%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S +E +N + A +LL LGED R+G+ KTP+R A A T+GY++ + +++
Sbjct: 51 SEEENQVNLPKLAAAYSSILLSLGEDPQRQGLLKTPWRAATAMQYFTKGYQETISDVLND 110
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V V+DID++S CE L+PF + H+GY+P N++V+GL
Sbjct: 111 AIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGRVHIGYLP-NKQVLGL 156
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 157 SKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHM 202
[95][TOP]
>UniRef100_UPI00016E2AFC UPI00016E2AFC related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E2AFC
Length = 198
Score = 126 bits (316), Expect = 1e-27
Identities = 63/157 (40%), Positives = 100/157 (63%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
S +E + K++L LGEDVNREG+ +TP R AKA T+GY +++ I+ GA+F E +
Sbjct: 17 SQMEKSYKNILTELGEDVNREGLLRTPLRAAKAMQFLTKGYNESIKEILNGAIFDENHEE 76
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+++S CE L+PF K H+ Y+P N++VVGLSKL R+ E
Sbjct: 77 -------------VVIVKDIEMFSLCEHHLVPFFGKAHIAYLP-NKKVVGLSKLARIVEV 122
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+++R Q +RL +I A+ E ++P GVA++++ H+
Sbjct: 123 YSRRFQVQERLTKQIASAISEALEPAGVAVVIEAVHM 159
[96][TOP]
>UniRef100_C6XWQ1 GTP cyclohydrolase I n=1 Tax=Pedobacter heparinus DSM 2366
RepID=C6XWQ1_PEDHD
Length = 210
Score = 126 bits (316), Expect = 1e-27
Identities = 67/157 (42%), Positives = 97/157 (61%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
+++ + KD+L LGED NREG+ KTP RVAKA T GY N I+ A+F E+
Sbjct: 27 AAVAHHYKDILGQLGEDPNREGLIKTPERVAKALQYLTHGYDLNPAEILRSAMFKED--- 83
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+++S CE +LPF K H+ YIP N +VGLSK+PR+ +A
Sbjct: 84 ----------YSQMVVVKDIEVFSMCEHHMLPFFGKAHIAYIP-NGHIVGLSKIPRIVDA 132
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ +RL NEI + + + P GVA++++C H+
Sbjct: 133 FARRLQVQERLTNEIRDCIQDTLMPAGVAVVIECKHL 169
[97][TOP]
>UniRef100_Q6FTV6 Similar to uniprot|P51601 Saccharomyces cerevisiae YGR267c FOL2 GTP
cyclohydrolase I n=1 Tax=Candida glabrata
RepID=Q6FTV6_CANGA
Length = 245
Score = 126 bits (316), Expect = 1e-27
Identities = 71/167 (42%), Positives = 106/167 (63%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIE 196
+ +E I AVK +L LGEDV REG+ TP R AKA T+GY+ N+++ +I
Sbjct: 52 TEEEEKQRTGRIADAVKVILEELGEDVTREGLLDTPQRYAKAMLFFTKGYQTNIMDDVIN 111
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E+ + +V VRDI++YS CE L+PF K H+GYIP N++V+G
Sbjct: 112 NAVFEEDHDE-------------MVIVRDIEIYSLCEHHLVPFFGKVHIGYIP-NKKVIG 157
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+AE +A+RLQ +RL +I +AL E ++P GVA++++ +H+
Sbjct: 158 LSKLARLAEMYARRLQVQERLTKQIAMALSEILKPLGVAVVIEASHM 204
[98][TOP]
>UniRef100_C5P4L9 GTP cyclohydrolase I, putative n=2 Tax=Coccidioides
RepID=C5P4L9_COCP7
Length = 338
Score = 126 bits (316), Expect = 1e-27
Identities = 69/171 (40%), Positives = 110/171 (64%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L S+ E + R + AV+ + +GED REG+ TP R AKA T+GY +NV
Sbjct: 142 ERLESTPEETEERIQKLAGAVRTIFECIGEDPEREGLLGTPERYAKAMLYFTKGYEENVR 201
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 202 DLVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DR 247
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL ++ LA+ E ++PQGVA++++ +H+
Sbjct: 248 RVLGLSKLARLAEMFSRRLQVQERLTKQVALAIAEVLKPQGVAVVMESSHL 298
[99][TOP]
>UniRef100_C0NTH8 GTP cyclohydrolase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NTH8_AJECG
Length = 390
Score = 126 bits (316), Expect = 1e-27
Identities = 69/171 (40%), Positives = 111/171 (64%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L ++ E S R+ + AV+ +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 194 ERLEATPEESEKRTQKLANAVRTVLECIGEDPEREGLLGTPERYAKALMYFTKGYEENVR 253
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE L+PF K H+GYIP ++
Sbjct: 254 DLVNGAVFHEDHDE-------------LVIVKDIEVFSLCEHHLVPFTGKMHIGYIP-DR 299
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSK R+AE F++RLQ +RL ++ LA+ E ++P+GVA++++ +H+
Sbjct: 300 RVLGLSKFARLAEMFSRRLQVQERLTKQVALAISEVLKPRGVAVVMESSHL 350
[100][TOP]
>UniRef100_A6S4P2 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S4P2_BOTFB
Length = 303
Score = 126 bits (316), Expect = 1e-27
Identities = 64/166 (38%), Positives = 109/166 (65%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S ++ +I + + AV+ +L +GED +REG+ TP R AKA T+GY++NV +I+
Sbjct: 110 SPEQAAIRMTKLTGAVRTILECIGEDPDREGLLATPERYAKALLYLTKGYQENVRDIVND 169
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + LV V+DI+++S CE ++PF K H+GYIP ++ V+G+
Sbjct: 170 AIFNEDHNE-------------LVIVKDIEVFSMCEHHMVPFTGKMHIGYIP-DRNVIGI 215
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKLPR+A+ F++RLQ +RL ++ A+ E ++PQGVA++++ +H+
Sbjct: 216 SKLPRIADMFSRRLQIQERLTKDVAHAVMEILKPQGVAVVMESSHL 261
[101][TOP]
>UniRef100_Q8DJB8 GTP cyclohydrolase 1 n=1 Tax=Thermosynechococcus elongatus BP-1
RepID=GCH1_THEEB
Length = 229
Score = 126 bits (316), Expect = 1e-27
Identities = 69/152 (45%), Positives = 99/152 (65%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LL +GED +REG+ KTP RVA+A T GY Q++ ++ GA+F +EG D
Sbjct: 49 AVRTILLNVGEDPDREGLLKTPKRVAEAMQFLTSGYSQSLETLVNGAIF-DEGHDE---- 103
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V VRDI+ +S CE +LPF K HV YIP NQRV+GLSKL RV E +A+RL
Sbjct: 104 --------MVLVRDINFFSLCEHHMLPFIGKAHVAYIP-NQRVIGLSKLARVVEMYARRL 154
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ A+ + P+GVA++++ TH+
Sbjct: 155 QVQERLTRQVAEAIETVLDPKGVAVVMEATHM 186
[102][TOP]
>UniRef100_B0CF69 GTP cyclohydrolase I n=1 Tax=Acaryochloris marina MBIC11017
RepID=B0CF69_ACAM1
Length = 232
Score = 125 bits (315), Expect = 2e-27
Identities = 67/152 (44%), Positives = 101/152 (66%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LLG+GED REG+ KTP RVA+A T GY+Q++ +++ A+F +EG D
Sbjct: 52 AVETMLLGVGEDPEREGLLKTPKRVAEAMRFLTSGYQQSLEDLVNNAIF-DEGHDE---- 106
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V VRDID +S CE +LPF K HV YIP NQ+V+GLSKL R+ E +++RL
Sbjct: 107 --------MVLVRDIDAFSLCEHHMLPFIGKAHVAYIP-NQKVIGLSKLARIVEMYSRRL 157
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++P+GVA++++ +H+
Sbjct: 158 QVQERLTRQIAEAVQTALEPKGVAVVMEASHM 189
[103][TOP]
>UniRef100_A7TNW0 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TNW0_VANPO
Length = 242
Score = 125 bits (315), Expect = 2e-27
Identities = 69/153 (45%), Positives = 103/153 (67%), Gaps = 1/153 (0%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN-IIEGALFPEEGLDNTNK 238
AVK +L LGEDV REG+ TP R AKA T+GY+ N+++ +I+ ALF E+ +
Sbjct: 63 AVKVILEELGEDVTREGLLDTPQRYAKAMLYFTKGYQTNIMDDVIKNALFEEDHDE---- 118
Query: 239 IGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKR 418
+V VRDI+++S CE L+PF K H+GYIP N++V+GLSKL R+AE +A+R
Sbjct: 119 ---------MVIVRDIEIFSLCEHHLVPFFGKVHIGYIP-NKKVLGLSKLARLAEMYARR 168
Query: 419 LQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LQ +RL +I +AL + ++P GVA++++ TH+
Sbjct: 169 LQVQERLTKQIAMALRDILKPIGVAVVIEATHM 201
[104][TOP]
>UniRef100_Q4C4T8 GTP cyclohydrolase I n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4C4T8_CROWT
Length = 218
Score = 125 bits (314), Expect = 2e-27
Identities = 68/172 (39%), Positives = 108/172 (62%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
++ L ++ +++ + AV+ LLLGLGED +REG++ TP RV KA T GY Q++
Sbjct: 17 KLPSLTTTKHPAVSEEEMRQAVRTLLLGLGEDPDREGLKDTPKRVVKALKFLTSGYNQSL 76
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
++ GA+F E+ TN+ +V VRDIDL+S CE +LP + HV YIP
Sbjct: 77 EELLNGAVFHED----TNE---------MVLVRDIDLFSSCEHHILPILGRVHVAYIPDG 123
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ R+ E + +RLQ +RL +I AL E ++P+GVA++++ +H+
Sbjct: 124 -KVIGLSKIARICEMYGRRLQAQERLTAQIADALQELLKPKGVAVLVEASHL 174
[105][TOP]
>UniRef100_A3IRZ7 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. CCY0110
RepID=A3IRZ7_9CHRO
Length = 218
Score = 125 bits (314), Expect = 2e-27
Identities = 69/172 (40%), Positives = 106/172 (61%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
++ L ++ + ++ + AV+ LLLGLGED +REG++ TP RV KA T GY Q++
Sbjct: 17 KLPSLTTTQQPPVSEEEMRQAVRTLLLGLGEDPDREGLKDTPKRVVKALKFLTSGYHQSL 76
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
++ GA+F E N N+ +V VRDIDL+S CE +LP + HV YIP
Sbjct: 77 DELLNGAVFHE----NANE---------MVLVRDIDLFSSCEHHILPILGRAHVAYIPDG 123
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ R+ E + +RLQ +RL +I AL +QP+GVA++++ TH+
Sbjct: 124 -KVIGLSKIARICEMYGRRLQVQERLTAQIADALQGLLQPKGVAVVVEATHM 174
[106][TOP]
>UniRef100_B0Y2R1 GTP cyclohydrolase I, putative n=2 Tax=Aspergillus fumigatus
RepID=B0Y2R1_ASPFC
Length = 334
Score = 125 bits (314), Expect = 2e-27
Identities = 63/152 (41%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ + +GED REG+R+TP R AKA T+GY +NV +++ GA+F E+ +
Sbjct: 157 AVRTIFECIGEDPEREGLRETPERYAKAMLYFTKGYEENVRDLVNGAVFHEDHDE----- 211
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DI+++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 212 --------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 262
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E ++P+GV ++++ +H+
Sbjct: 263 QVQERLTKQVALAISEVLKPRGVGVVMESSHL 294
[107][TOP]
>UniRef100_A6QSY1 GTP cyclohydrolase I n=1 Tax=Ajellomyces capsulatus NAm1
RepID=A6QSY1_AJECN
Length = 390
Score = 125 bits (314), Expect = 2e-27
Identities = 68/171 (39%), Positives = 111/171 (64%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L ++ E + R+ + AV+ +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 194 ERLEATPEENEKRTQKLANAVRTVLECIGEDPEREGLLGTPERYAKALMYFTKGYEENVR 253
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE L+PF K H+GYIP ++
Sbjct: 254 DLVNGAVFHEDHDE-------------LVIVKDIEIFSLCEHHLVPFTGKMHIGYIP-DR 299
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSK R+AE F++RLQ +RL ++ LA+ E ++P+GVA++++ +H+
Sbjct: 300 RVLGLSKFARLAEMFSRRLQVQERLTKQVALAISEVLKPRGVAVVIESSHL 350
[108][TOP]
>UniRef100_A1D001 GTP cyclohydrolase I, putative n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1D001_NEOFI
Length = 334
Score = 125 bits (314), Expect = 2e-27
Identities = 63/152 (41%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ + +GED REG+R+TP R AKA T+GY +NV +++ GA+F E+ +
Sbjct: 157 AVRTIFECIGEDPEREGLRETPERYAKAMLYFTKGYEENVRDLVNGAVFHEDHDE----- 211
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DI+++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 212 --------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 262
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E ++P+GV ++++ +H+
Sbjct: 263 QVQERLTKQVALAISEVLKPRGVGVVMESSHL 294
[109][TOP]
>UniRef100_A1C522 GTP cyclohydrolase I, putative n=1 Tax=Aspergillus clavatus
RepID=A1C522_ASPCL
Length = 335
Score = 125 bits (314), Expect = 2e-27
Identities = 63/152 (41%), Positives = 102/152 (67%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ + +GED REG+R+TP R AKA T+GY +NV +++ GA+F E+ +
Sbjct: 158 AVRTIFECIGEDPEREGLRETPERYAKAMLYFTKGYEENVRDLVNGAVFHEDHDE----- 212
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DI+++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 213 --------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 263
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E ++P+GV ++++ +H+
Sbjct: 264 QVQERLTKQVALAISEVLKPRGVGVVMESSHL 295
[110][TOP]
>UniRef100_B5UB79 GTP cyclohydrolase 2 n=1 Tax=Paralichthys olivaceus
RepID=B5UB79_PAROL
Length = 221
Score = 125 bits (313), Expect = 3e-27
Identities = 63/156 (40%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L LGED +R+G+ +TP R AKA T+GY + + +I+ A+F E+ +
Sbjct: 40 ALEAAYTSILQELGEDTDRQGLLRTPLRAAKAMQFLTKGYHETIDDILNNAIFDEDHDE- 98
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID++S CE L+PF K H+GYIP N++VVGLSKL R+ E F
Sbjct: 99 ------------MVIVKDIDVFSLCEHHLVPFFGKVHIGYIP-NKKVVGLSKLARIVEIF 145
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I + + E +QP+GVA++++ +H+
Sbjct: 146 SRRLQVQERLTKQIAMGISEALQPKGVAVVIEASHM 181
[111][TOP]
>UniRef100_Q3MA34 GTP cyclohydrolase n=1 Tax=Anabaena variabilis ATCC 29413
RepID=Q3MA34_ANAVT
Length = 235
Score = 125 bits (313), Expect = 3e-27
Identities = 66/152 (43%), Positives = 98/152 (64%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L+G+GED REG+ KTP RVA+A T GY Q++ ++ GA+F E
Sbjct: 54 AVRSILVGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELLNGAVFDE--------- 104
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGLSKL R+ E +++RL
Sbjct: 105 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIVEMYSRRL 159
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++PQGVA++++ +H+
Sbjct: 160 QVQERLTRQIAEAVQTILEPQGVAVVMEASHM 191
[112][TOP]
>UniRef100_Q4BWY2 GTP cyclohydrolase I n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4BWY2_CROWT
Length = 241
Score = 125 bits (313), Expect = 3e-27
Identities = 70/166 (42%), Positives = 107/166 (64%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+S++ S++R +E AV +L LGED REG+ KTP RVA+A T+GY Q++ ++ G
Sbjct: 48 TSNDESMDR--MEEAVYTMLEELGEDPEREGLLKTPKRVAEAMKFLTQGYNQSLEELVNG 105
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGL
Sbjct: 106 AIFDE-------------GHNEMVLVRDINFFSLCEHHMLPFMGQAHVAYIP-NQKVVGL 151
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I A+ E ++P+GVA++++ +H+
Sbjct: 152 SKLARIVEMYSRRLQVQERLTRQIAEAIQEILEPRGVAVVIEASHM 197
[113][TOP]
>UniRef100_Q5KLK7 GTP cyclohydrolase I, putative n=1 Tax=Filobasidiella neoformans
RepID=Q5KLK7_CRYNE
Length = 435
Score = 125 bits (313), Expect = 3e-27
Identities = 65/164 (39%), Positives = 107/164 (65%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+E S N + A++ +L +GED +REG+++TP R AKA T+GY + ++++I A+
Sbjct: 241 EEKSANMELLTSALRTVLECIGEDPDREGLQRTPERYAKALLWMTKGYEERLVDVINDAV 300
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F E+ + +V VRDI+++S CE L+PF K +GYIPS + V+GLSK
Sbjct: 301 FAEDHDE-------------MVIVRDIEVFSLCEHHLVPFTGKISIGYIPS-KLVLGLSK 346
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE F++RLQ +RL ++ LA+ E I+P+GVA++++ +H+
Sbjct: 347 LARIAETFSRRLQVQERLTKQVALAVEEAIRPRGVAVVMEASHM 390
[114][TOP]
>UniRef100_C6HE89 GTP cyclohydrolase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HE89_AJECH
Length = 390
Score = 125 bits (313), Expect = 3e-27
Identities = 69/171 (40%), Positives = 110/171 (64%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L ++ E S R+ + AV+ +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 194 ERLEATPEESEKRTQKLANAVRTVLECIGEDPEREGLLGTPERYAKALMYFTKGYEENVR 253
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ GA+F E+ + LV V+DI+++S CE L+PF K H+GYIP +
Sbjct: 254 DLVNGAVFHEDHDE-------------LVIVKDIEIFSLCEHHLVPFTGKMHIGYIP-DC 299
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSK R+AE F++RLQ +RL ++ LA+ E ++P+GVA++++ +H+
Sbjct: 300 RVLGLSKFARLAEMFSRRLQVQERLTKQVALAISEVLKPRGVAVVMESSHL 350
[115][TOP]
>UniRef100_Q8YLL1 GTP cyclohydrolase 1 1 n=1 Tax=Nostoc sp. PCC 7120
RepID=GCH11_ANASP
Length = 235
Score = 125 bits (313), Expect = 3e-27
Identities = 66/152 (43%), Positives = 98/152 (64%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L+G+GED REG+ KTP RVA+A T GY Q++ ++ GA+F E
Sbjct: 54 AVRSILVGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELLNGAVFDE--------- 104
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGLSKL R+ E +++RL
Sbjct: 105 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIVEMYSRRL 159
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++PQGVA++++ +H+
Sbjct: 160 QVQERLTRQIAEAVQTILEPQGVAVVMEASHM 191
[116][TOP]
>UniRef100_UPI00016E02DE UPI00016E02DE related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E02DE
Length = 237
Score = 124 bits (312), Expect = 4e-27
Identities = 64/156 (41%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L LGED++R+G+ +TP R AKA T+GY + V +I+ ALF E+ +
Sbjct: 57 ALEAAYTCILRELGEDMDRQGLLRTPLRAAKAMQFLTKGYHETVDDILNNALFDEDHDE- 115
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID++S CE L+PF K H+GYIP N++VVGLSKL R+ E +
Sbjct: 116 ------------MVIVKDIDMFSLCEHHLVPFFGKVHIGYIP-NKKVVGLSKLARIVEIY 162
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL ++ L + E +QP+GVA++++ H+
Sbjct: 163 SRRLQVQERLTKQVALGISEALQPKGVAVVIEAVHM 198
[117][TOP]
>UniRef100_C2BSB2 GTP cyclohydrolase I n=1 Tax=Mobiluncus curtisii ATCC 43063
RepID=C2BSB2_9ACTO
Length = 191
Score = 124 bits (312), Expect = 4e-27
Identities = 71/161 (44%), Positives = 97/161 (60%)
Frame = +2
Query: 35 SINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPE 214
S N + AV+DLL+ +GED +REG+R TP R+A++F E +GYR++ +E +FP
Sbjct: 4 SYNPDGVTQAVRDLLVAVGEDPDREGLRDTPERMARSFAEMLQGYREDPKKHLE-RMFPV 62
Query: 215 EGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPR 394
E D LV V+DI S CE LLPF HVGYIP +RV GLSKL R
Sbjct: 63 EHND-------------LVLVKDIPFNSMCEHHLLPFVGLAHVGYIPQGKRVTGLSKLAR 109
Query: 395 VAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ + +A RLQ +RL +I AL + +QPQGV ++LQ H+
Sbjct: 110 LVDGYAHRLQVQERLTQQIADALWDVLQPQGVIVVLQAEHM 150
[118][TOP]
>UniRef100_B9YH83 GTP cyclohydrolase I n=1 Tax='Nostoc azollae' 0708
RepID=B9YH83_ANAAZ
Length = 235
Score = 124 bits (312), Expect = 4e-27
Identities = 64/152 (42%), Positives = 98/152 (64%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L+G+GED REG+ KTP RVA+A T GY Q++ ++ GA+F E
Sbjct: 54 AVRTMLIGVGEDPEREGLLKTPKRVAEAMMFLTGGYNQSLEELVNGAIFDE--------- 104
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ ++ CE +LPF + HV YIP NQ+VVGLSK+ R+ E +++RL
Sbjct: 105 ----GHNEMVLVRDINFFTLCEHHMLPFMGRAHVAYIP-NQKVVGLSKMARIVEMYSRRL 159
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++P+GVA++++ TH+
Sbjct: 160 QVQERLTRQIAEAVQTILEPKGVAVVMEATHM 191
[119][TOP]
>UniRef100_A6EU75 GTP cyclohydrolase I n=1 Tax=unidentified eubacterium SCB49
RepID=A6EU75_9BACT
Length = 199
Score = 124 bits (312), Expect = 4e-27
Identities = 65/149 (43%), Positives = 98/149 (65%)
Frame = +2
Query: 71 DLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHG 250
++L G+GEDV+REGI KTP R AKA T G+ Q+ I++ A+F E+ D
Sbjct: 24 NILKGIGEDVDREGIVKTPERAAKAMQFLTSGHNQDPAEILKSAMFAEDYND-------- 75
Query: 251 GGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEP 430
+V ++DI+LYS CE +LPF K H+ YIP N +VGLSK+PRV + FA+RLQ
Sbjct: 76 -----MVIIKDIELYSLCEHHILPFFGKAHIAYIP-NGHIVGLSKIPRVVDIFARRLQVQ 129
Query: 431 QRLANEICLALHEGIQPQGVAIILQCTHI 517
+RL ++I ++E ++PQGVA++++ +H+
Sbjct: 130 ERLTHDILECINETLKPQGVAVVIEASHM 158
[120][TOP]
>UniRef100_UPI00005453A5 PREDICTED: similar to GTP cyclohydrolase 1 precursor (GTP
cyclohydrolase I) (GTP-CH-I) n=1 Tax=Danio rerio
RepID=UPI00005453A5
Length = 251
Score = 124 bits (311), Expect = 5e-27
Identities = 63/170 (37%), Positives = 107/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ SI A +L GLGED R+G+ KTP+R A A T+GY++ +++
Sbjct: 57 ERTRSLEDNEMSLPSIAAAYTTILRGLGEDPQRQGLLKTPWRAATAMQFFTKGYQEKIID 116
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+P + H+GY+P N+R
Sbjct: 117 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPIFGRVHIGYLP-NKR 162
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 163 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVVEATHM 212
[121][TOP]
>UniRef100_UPI00005220E8 PREDICTED: similar to abnormal CATecholamine distribution family
member (cat-4) n=1 Tax=Ciona intestinalis
RepID=UPI00005220E8
Length = 222
Score = 124 bits (311), Expect = 5e-27
Identities = 67/161 (41%), Positives = 102/161 (63%)
Frame = +2
Query: 35 SINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPE 214
S + +E A + +L +GEDVNR+GI KTP R A+A T+GY +N+ I+ A+F E
Sbjct: 36 SNQHNRLEGAFRSILEEIGEDVNRQGILKTPKRAAEAIKFFTKGYNENLQEIVNEAIFDE 95
Query: 215 EGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPR 394
+ D +V V+DID++S CE L+PF K +GYIP N+RV+G+SKL R
Sbjct: 96 DHDD-------------IVIVKDIDMFSMCEHHLVPFTGKVAIGYIP-NKRVLGISKLAR 141
Query: 395 VAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ E +++RLQ +RL +I AL E I+P GVA++++ +H+
Sbjct: 142 IVEMYSRRLQVQERLTKQIASALVEVIEPSGVAVVIEASHM 182
[122][TOP]
>UniRef100_C1BKK9 GTP cyclohydrolase I n=1 Tax=Osmerus mordax RepID=C1BKK9_OSMMO
Length = 241
Score = 124 bits (311), Expect = 5e-27
Identities = 62/156 (39%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE A +L GLGE+ +R+G+ +TP R AKA T+GY + + +I+ A+F E+ +
Sbjct: 60 AIEAAYTTILRGLGENTDRQGLLRTPLRAAKAMQFLTKGYHETIYDILNDAIFDEDHDE- 118
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V++ID++S CE L+PF K H+GY+P N++VVGLSKL R+ E +
Sbjct: 119 ------------MVIVKEIDVFSLCEHHLVPFFGKVHIGYLP-NKKVVGLSKLARIVEIY 165
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I +A+ E +QP GVA++++ H+
Sbjct: 166 SRRLQVQERLTKQIAMAISEALQPAGVAVVIEAAHM 201
[123][TOP]
>UniRef100_Q72HH0 GTP cyclohydrolase I n=1 Tax=Thermus thermophilus HB27
RepID=Q72HH0_THET2
Length = 207
Score = 124 bits (311), Expect = 5e-27
Identities = 69/179 (38%), Positives = 105/179 (58%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L + EV + R ++ + L +GED REG+ KTP RVAKA+ TRGYRQ + ++
Sbjct: 13 LTFATEVDLER--LQALAAEWLQVIGEDPGREGLLKTPERVAKAWAFLTRGYRQRLEEVV 70
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
GA+FP EG + +V V+ ++ YS CE LLPF K H+GYIP +++
Sbjct: 71 GGAVFPAEGSE-------------MVVVKGVEFYSMCEHHLLPFFGKVHIGYIPDG-KIL 116
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
GLSK R+ + FA+RLQ +RLA +I A+ E ++PQGV ++++ H+ + + H
Sbjct: 117 GLSKFARIVDMFARRLQVQERLAVQIAEAIQEVLEPQGVGVVVEGVHLCMMMRGVEKQH 175
[124][TOP]
>UniRef100_Q5SH52 GTP cyclohydrolase I n=1 Tax=Thermus thermophilus HB8
RepID=Q5SH52_THET8
Length = 220
Score = 124 bits (311), Expect = 5e-27
Identities = 69/179 (38%), Positives = 105/179 (58%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L + EV + R ++ + L +GED REG+ KTP RVAKA+ TRGYRQ + ++
Sbjct: 27 LTFATEVDLER--LQALAAEWLQVIGEDPGREGLLKTPERVAKAWAFLTRGYRQRLEEVV 84
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
GA+FP EG + +V V+ ++ YS CE LLPF K H+GYIP +++
Sbjct: 85 GGAVFPAEGSE-------------MVVVKGVEFYSMCEHHLLPFFGKVHIGYIPDG-KIL 130
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
GLSK R+ + FA+RLQ +RLA +I A+ E ++PQGV ++++ H+ + + H
Sbjct: 131 GLSKFARIVDMFARRLQVQERLAVQIAEAIQEVLEPQGVGVVVEGVHLCMMMRGVEKQH 189
[125][TOP]
>UniRef100_A8EVB6 GTP cyclohydrolase I n=1 Tax=Arcobacter butzleri RM4018
RepID=A8EVB6_ARCB4
Length = 190
Score = 124 bits (311), Expect = 5e-27
Identities = 69/154 (44%), Positives = 99/154 (64%)
Frame = +2
Query: 56 EYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTN 235
E A+K++L +GED+NREG+ TP RV KAF GY Q+ II+ ALF +TN
Sbjct: 8 ENAIKNILTYIGEDINREGLLDTPKRVRKAFEFMCSGYNQDPKEIIQKALFT-----STN 62
Query: 236 KIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAK 415
+V V+DI+ YS+CE +LP K HV YIP N +VVGLSK+PRV + FA+
Sbjct: 63 D--------EMVVVKDIEFYSFCEHHMLPIIGKAHVAYIP-NGKVVGLSKIPRVVDVFAR 113
Query: 416 RLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RLQ +++ +IC AL+E ++P+GVA+++ H+
Sbjct: 114 RLQIQEQMTEQICEALNEHLRPKGVAVMIDARHM 147
[126][TOP]
>UniRef100_B4WJ44 GTP cyclohydrolase I n=1 Tax=Synechococcus sp. PCC 7335
RepID=B4WJ44_9SYNE
Length = 249
Score = 124 bits (311), Expect = 5e-27
Identities = 68/152 (44%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LL +GED REG+ KTP RVA+A T+GY Q++ I+ A+F E
Sbjct: 66 AVRTMLLSVGEDPEREGLLKTPHRVAEAMRFLTQGYSQSLETIVNDAIFDE--------- 116
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQRVVGLSKL R+ E +A+RL
Sbjct: 117 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQRVVGLSKLARIVEMYARRL 171
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ E + P GVA++++ +H+
Sbjct: 172 QVQERLNRQIAEAVQEVLDPLGVAVVMEASHM 203
[127][TOP]
>UniRef100_C4JM52 GTP cyclohydrolase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM52_UNCRE
Length = 338
Score = 124 bits (311), Expect = 5e-27
Identities = 64/152 (42%), Positives = 101/152 (66%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ + +GED REG+ TP R AKA T+GY +NV +++ GA+F E+ +
Sbjct: 161 AVRTIFECIGEDPEREGLLGTPERYAKAMLYFTKGYEENVRDLVNGAVFHEDHDE----- 215
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DI+++S CE ++PF K H+GYIP ++RV+GLSKL R+AE F++RL
Sbjct: 216 --------LVIVKDIEVFSLCEHHMVPFTGKMHIGYIP-DRRVLGLSKLARLAEMFSRRL 266
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ LA+ E ++PQGVA++++ +H+
Sbjct: 267 QVQERLTKQVALAIAEVLKPQGVAVVMESSHL 298
[128][TOP]
>UniRef100_Q2JPT8 GTP cyclohydrolase 1 n=1 Tax=Synechococcus sp. JA-2-3B'a(2-13)
RepID=GCH1_SYNJB
Length = 229
Score = 124 bits (311), Expect = 5e-27
Identities = 73/170 (42%), Positives = 105/170 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+L SSD ++ ++ AV+ LL G+GED REG+RKTP RV A T GYRQ++
Sbjct: 34 EELGSSD---VSDPAMVAAVETLLRGIGEDPQREGLRKTPERVVAALKFLTSGYRQSLEE 90
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F +EG D +V +RD+ L+S CE LLPF K HV YIP Q+
Sbjct: 91 LLNSAIF-DEGHDE------------MVLLRDVSLFSLCEHHLLPFIGKAHVAYIPK-QK 136
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
VVGLSK+ R+ E +++RLQ +RL +I AL E + P GV ++++ TH+
Sbjct: 137 VVGLSKIARIVEMYSRRLQVQERLTRQIAEALMEVLDPYGVGVVIEATHM 186
[129][TOP]
>UniRef100_B7A8L3 GTP cyclohydrolase I n=1 Tax=Thermus aquaticus Y51MC23
RepID=B7A8L3_THEAQ
Length = 204
Score = 124 bits (310), Expect = 7e-27
Identities = 67/183 (36%), Positives = 109/183 (59%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
E+E+ + E ++ +E + L +GED NREG+ KTP RVAKA+ TRGYRQ++
Sbjct: 7 EIEETGLTFETELDLGRLEGLAAEWLQVIGEDPNREGLLKTPERVAKAWAFLTRGYRQSL 66
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
I+ GA+F EG + +V V+ I+ YS CE +LPF + H+GYIP
Sbjct: 67 EEIVNGAVFRAEGSE-------------MVVVKGIEFYSLCEHHMLPFFGQVHIGYIP-G 112
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFD 541
++++GLSK R+ + FA+RLQ +RLA +I A+ + ++P+GV ++++ H+ + +
Sbjct: 113 EKILGLSKFARIVDLFARRLQVQERLAVQIAEAIQQVLEPRGVGVVVEGVHLCMMMRGVE 172
Query: 542 SNH 550
H
Sbjct: 173 KQH 175
[130][TOP]
>UniRef100_B5W0I2 GTP cyclohydrolase I n=1 Tax=Arthrospira maxima CS-328
RepID=B5W0I2_SPIMA
Length = 239
Score = 124 bits (310), Expect = 7e-27
Identities = 66/152 (43%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LLG+GED REG+ KTP RVA A T GY Q++ ++ A+F E
Sbjct: 59 AVETILLGVGEDPEREGLLKTPKRVADAMRFLTNGYSQSLEELVNDAIFDE--------- 109
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF K HV YIP NQ+V+GLSKL RV E +++RL
Sbjct: 110 ----GHEEMVLVRDINFFSLCEHHMLPFMGKAHVAYIP-NQKVIGLSKLARVVEMYSRRL 164
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL ++ A+ ++PQGVA++++ +H+
Sbjct: 165 QVQERLTRQVAEAIQSVLEPQGVAVVMEASHM 196
[131][TOP]
>UniRef100_A0ZJZ3 GTP cyclohydrolase I n=1 Tax=Nodularia spumigena CCY9414
RepID=A0ZJZ3_NODSP
Length = 236
Score = 124 bits (310), Expect = 7e-27
Identities = 65/171 (38%), Positives = 104/171 (60%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
+ L + + + + + AV+ LL+GLGED +REG++ TP RV KA T+GY ++
Sbjct: 36 ISSLTAQKQPKVTEAEMMQAVRTLLIGLGEDPDREGLKDTPKRVMKALQFLTKGYTDSLD 95
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++ GA+F E+ + +V VRDID++S CE +LP + HV YIP N
Sbjct: 96 ELLNGAVFTEDANE-------------MVLVRDIDIFSSCEHHILPIIGRAHVAYIP-NG 141
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ R+ E + +RLQ +RL +I AL ++PQGVA++++ TH+
Sbjct: 142 KVIGLSKIARICEMYGRRLQVQERLTTQIADALQGLLKPQGVAVVVEATHM 192
[132][TOP]
>UniRef100_Q04P36 GTP cyclohydrolase 1 n=2 Tax=Leptospira borgpetersenii serovar
Hardjo-bovis RepID=GCH1_LEPBJ
Length = 183
Score = 124 bits (310), Expect = 7e-27
Identities = 60/155 (38%), Positives = 96/155 (61%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E + ++L +GED REG+ TP RV KA+ T GY ++ ++ GA+F E
Sbjct: 1 MEENIVNILKSIGEDPTREGLLNTPKRVKKAYDFLTSGYHVDITKVVNGAIFEES----- 55
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
G++ VRDI++YS CE LLPF + HV Y+P N++++G+SK+PR+ + FA
Sbjct: 56 --------TEGMILVRDIEVYSLCEHHLLPFYGRAHVAYLP-NKKIIGISKIPRIVDVFA 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I A+ E + PQGVA++++ H+
Sbjct: 107 RRLQVQERLTEQIAYAVQEVLDPQGVAVVIKAKHL 141
[133][TOP]
>UniRef100_UPI00016EA5B3 UPI00016EA5B3 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016EA5B3
Length = 257
Score = 123 bits (309), Expect = 9e-27
Identities = 62/170 (36%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ S+ A +L GLGED R+G+ KTP+R A A T+GY++ +++
Sbjct: 63 ERTRSVEDNEMSLPSLAAAYTTILRGLGEDTQRQGLLKTPWRAATAMQFFTKGYQEKIVD 122
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+P K H+GY+P N+R
Sbjct: 123 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPIFGKVHIGYLP-NKR 168
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E + P GV ++++ TH+
Sbjct: 169 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALHPTGVGVVIEATHM 218
[134][TOP]
>UniRef100_UPI00003AE0AC GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I). n=1 Tax=Gallus
gallus RepID=UPI00003AE0AC
Length = 236
Score = 123 bits (309), Expect = 9e-27
Identities = 62/170 (36%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ S+ A +L LGED R+G+ KTP+R A A T+GY++ + +
Sbjct: 42 ERPRSEEDNELSLPSLAAAYTTILRALGEDPERQGLLKTPWRAATAMQFFTKGYQETIAD 101
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 102 VLNDAIFDEDHDE-------------MVIVKDIDMFSLCEHHLVPFVGKVHIGYLP-NKQ 147
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 148 VLGLSKLARIVEIYSRRLQVQERLTKQIAIAITEALQPAGVGVVIEATHM 197
[135][TOP]
>UniRef100_Q6DIE0 GTP cyclohydrolase 1 n=1 Tax=Xenopus (Silurana) tropicalis
RepID=Q6DIE0_XENTR
Length = 247
Score = 123 bits (309), Expect = 9e-27
Identities = 62/170 (36%), Positives = 105/170 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N S+ A +L LGED R+G+ KTP+R A A T+GY++ + +
Sbjct: 53 ERARSEEDNELNLPSLATAYGTILRALGEDPGRQGLLKTPWRAATAMQYFTKGYQETISD 112
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 113 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFIGKVHIGYLP-NKQ 158
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E + P GV ++++ TH+
Sbjct: 159 VLGLSKLARIVEIYSRRLQVQERLTKQIAIAITEALHPSGVGVVVEATHM 208
[136][TOP]
>UniRef100_C7QLK1 GTP cyclohydrolase I n=2 Tax=Cyanothece RepID=C7QLK1_CYAP0
Length = 239
Score = 123 bits (308), Expect = 1e-26
Identities = 66/152 (43%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L LGED REG+ KTP RVA+A T GY Q++ ++ GA+F E
Sbjct: 58 AVRTMLEALGEDPEREGLLKTPKRVAEAMAFLTEGYSQSLETLVNGAIFDE--------- 108
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGLSKL R+ E +++RL
Sbjct: 109 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIVEMYSRRL 163
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ E + P+GVA++++ +H+
Sbjct: 164 QVQERLTRQIAEAVQEILDPRGVAVVMEASHM 195
[137][TOP]
>UniRef100_A0YRC3 GTP cyclohydrolase I n=1 Tax=Lyngbya sp. PCC 8106
RepID=A0YRC3_9CYAN
Length = 231
Score = 123 bits (308), Expect = 1e-26
Identities = 67/152 (44%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LLG+GED REG+ KTP RVA A T GY Q++ +++ A+F E
Sbjct: 51 AVRTMLLGVGEDPEREGLLKTPKRVADAMRFLTSGYNQSLEDLVNEAIFDE--------- 101
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI ++S CE +LPF K HV YIP NQ+V+GLSKL R+ E +A+RL
Sbjct: 102 ----GHEEMVLVRDITVFSMCEHHMLPFMGKAHVAYIP-NQKVIGLSKLARIVEMYARRL 156
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ + PQGVA++++ +H+
Sbjct: 157 QVQERLTRQIAEAVQGVLDPQGVAVVIEASHM 188
[138][TOP]
>UniRef100_A7RNY6 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RNY6_NEMVE
Length = 208
Score = 123 bits (308), Expect = 1e-26
Identities = 63/168 (37%), Positives = 105/168 (62%), Gaps = 2/168 (1%)
Frame = +2
Query: 20 SSDEVSINR--SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
++DE ++ + ++I A + +L +GED +R+G+ KTP R AKA T+GY + V I+
Sbjct: 13 ATDEATVGKEVAAISKAYETILSNIGEDKDRQGLLKTPERAAKAMLYFTKGYEEKVQEIL 72
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
A+F E+ + LV V+DI+++S CE L+PF K H+GY+P N+++V
Sbjct: 73 NDAVFDEDHDE-------------LVIVKDIEMFSLCEHHLVPFMGKVHIGYLP-NKKIV 118
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
GLSKL R+ E F++RLQ +RL +I +A+ E + P GV ++++ H+
Sbjct: 119 GLSKLARLVEMFSRRLQVQERLTKQIAMAIVEAVNPAGVGVVIEAKHM 166
[139][TOP]
>UniRef100_B6K3T4 GTP cyclohydrolase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6K3T4_SCHJY
Length = 233
Score = 123 bits (308), Expect = 1e-26
Identities = 69/170 (40%), Positives = 105/170 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E++ +S+E + +I AV +L LGED R+G+ TP R AKA T+GY +N+
Sbjct: 40 ERMETSEEEKVK--TISNAVSTILKCLGEDPTRQGLLGTPERYAKAMLYFTKGYEENLRE 97
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
+I A+F EE D +V VRDI+++S CE L+PF K H+GYIP +R
Sbjct: 98 VINNAVF-EENHDE------------MVIVRDIEVFSLCEHHLVPFIGKIHIGYIP-RKR 143
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+A FA+RLQ +RL ++ ++ + + PQGVA++++ TH+
Sbjct: 144 VLGLSKLARIANMFARRLQVQERLTKQVAQSIQKVLNPQGVAVVMEATHM 193
[140][TOP]
>UniRef100_B8HSZ7 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. PCC 7425
RepID=B8HSZ7_CYAP4
Length = 235
Score = 122 bits (307), Expect = 1e-26
Identities = 66/152 (43%), Positives = 99/152 (65%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +LLG+GE+ REG+ KTP RVA+A T GY Q++ ++ GA+F +EG D
Sbjct: 55 AVRSILLGVGENPEREGLLKTPKRVAEAMMFLTGGYSQSLEELVNGAIF-DEGHDE---- 109
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V VRDI +S CE +LPF K HV YIP NQ+V+GLSKL R+ E +++RL
Sbjct: 110 --------MVLVRDIHAFSLCEHHMLPFIGKAHVAYIP-NQKVIGLSKLARIVEMYSRRL 160
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++P+GVA++++ +H+
Sbjct: 161 QVQERLTRQIAEAVQTVLEPKGVAVVMEASHM 192
[141][TOP]
>UniRef100_A9B5F8 GTP cyclohydrolase I n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
RepID=A9B5F8_HERA2
Length = 206
Score = 122 bits (307), Expect = 1e-26
Identities = 69/158 (43%), Positives = 96/158 (60%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
R +E AV+ +L GLGEDV+REG+++TP RVAK F E T GY + + +I A+F E
Sbjct: 19 REDMEAAVRTILEGLGEDVDREGLQRTPHRVAKMFGELTAGYHTDPVALINDAIFTVE-- 76
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+V VRDI+ S CE +LPF K HV Y+P N +V+GLSK+PR+ +
Sbjct: 77 -----------YNEMVLVRDIEFSSLCEHHMLPFWGKAHVAYVP-NGKVLGLSKIPRIVD 124
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FAKRLQ +RL EI + + I GVA+++Q H+
Sbjct: 125 MFAKRLQVQERLTREIADFVAQTIDASGVAVVVQGAHM 162
[142][TOP]
>UniRef100_A6EK86 GTP cyclohydrolase I n=1 Tax=Pedobacter sp. BAL39
RepID=A6EK86_9SPHI
Length = 210
Score = 122 bits (307), Expect = 1e-26
Identities = 68/157 (43%), Positives = 95/157 (60%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
+SI D+L LGE+ REG+ KTP RVAKA T GY N I+ GA+F E+
Sbjct: 27 ASIANHYTDILSKLGENPEREGLIKTPERVAKALQYLTHGYDLNPAEILRGAMFKED--- 83
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+++S CE +LPF K H+ YIP N +VGLSK+PRV +A
Sbjct: 84 ----------YSQMVVVKDIEVFSMCEHHMLPFFGKAHIAYIP-NGHIVGLSKIPRVVDA 132
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ +RL NEI + + + P GVA++++C H+
Sbjct: 133 FARRLQVQERLTNEIRDCIQDTLNPVGVAVVIECKHL 169
[143][TOP]
>UniRef100_A0Z9X1 GTP cyclohydrolase I n=1 Tax=Nodularia spumigena CCY9414
RepID=A0Z9X1_NODSP
Length = 235
Score = 122 bits (307), Expect = 1e-26
Identities = 65/151 (43%), Positives = 96/151 (63%)
Frame = +2
Query: 65 VKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIG 244
V+ +++G+GED REG+ KTP RVA+A T GY Q++ ++ A+F E
Sbjct: 55 VRAIIVGVGEDPEREGLLKTPKRVAEAMQFLTSGYNQSLEELLNDAIFDE---------- 104
Query: 245 HGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQ 424
G +V VRDI+ +S CE +LPF K HV YIP NQ+VVGLSKL R+ E +++RLQ
Sbjct: 105 ---GHNEMVLVRDINFFSLCEHHMLPFMGKAHVAYIP-NQKVVGLSKLARIVEMYSRRLQ 160
Query: 425 EPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RL +I A+ ++PQGVA++++ TH+
Sbjct: 161 VQERLTRQIAEAIQTILEPQGVAVVMEATHM 191
[144][TOP]
>UniRef100_C4JSS5 GTP cyclohydrolase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JSS5_UNCRE
Length = 243
Score = 122 bits (307), Expect = 1e-26
Identities = 65/172 (37%), Positives = 106/172 (61%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
++E ++ D I + + AV+ +L +GED REG+R TP R AKA T+GY ++V
Sbjct: 48 QLESTLNGDGDRIRK--LAKAVRTILECVGEDPEREGLRTTPERYAKAMLYFTKGYAEDV 105
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+++ GA+F E GLV VRDID++S CE ++PF K H+GYIP
Sbjct: 106 QSLVNGAIFHEN-------------YDGLVIVRDIDVFSLCEHHVVPFTGKMHIGYIPDG 152
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
R++GLSK+ R+AE F++RLQ +RL ++ + + + + P+GV +I++ +H+
Sbjct: 153 -RILGLSKVARLAEIFSRRLQIQERLTKQVAMTIFDVLNPKGVGVIMESSHL 203
[145][TOP]
>UniRef100_B0CRX4 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
RepID=B0CRX4_LACBS
Length = 181
Score = 122 bits (307), Expect = 1e-26
Identities = 65/152 (42%), Positives = 99/152 (65%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ +L +GED +REG+++TP R A+A TRGY + + ++I A+F E+ +
Sbjct: 4 AVRTILECIGEDPDREGLQRTPERYAQAIMWMTRGYEERLADVINDAVFAEDHDE----- 58
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V VRDID+ S CE L+PF K + YIP NQ V+GLSKL R+AE F++RL
Sbjct: 59 --------MVLVRDIDISSLCEHHLVPFTGKIAIAYIP-NQLVLGLSKLARIAETFSRRL 109
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I +A+ E I+P+GVA++++ TH+
Sbjct: 110 QVQERLTKQIAIAVQEAIKPRGVAVVMEATHL 141
[146][TOP]
>UniRef100_P22288 GTP cyclohydrolase 1 n=1 Tax=Rattus norvegicus RepID=GCH1_RAT
Length = 241
Score = 122 bits (307), Expect = 1e-26
Identities = 60/166 (36%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S ++ +N ++ A +L LGED R+G+ KTP+R A A T+GY++ + +++
Sbjct: 51 SEEDNELNLPNLAAAYSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISDVLND 110
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V V+DID++S CE L+PF + H+GY+P N++V+GL
Sbjct: 111 AIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGRVHIGYLP-NKQVLGL 156
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 157 SKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHM 202
[147][TOP]
>UniRef100_UPI00017B39B2 UPI00017B39B2 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B39B2
Length = 244
Score = 122 bits (306), Expect = 2e-26
Identities = 62/156 (39%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L LGED++R+G+ +TP R AKA T+GY + V +++ A+F E+ +
Sbjct: 63 ALETAYTCILRELGEDLDRQGLLRTPLRAAKAMQFLTKGYHETVDDVLNNAIFDEDHDE- 121
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID++S CE L+PF K H+GYIP N++VVGLSKL RV E +
Sbjct: 122 ------------MVIVKDIDMFSLCEHHLVPFFGKVHIGYIP-NKKVVGLSKLARVVEIY 168
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL ++ + + E +QP+GVA++++ H+
Sbjct: 169 SRRLQVQERLTKQVAVGIWEALQPKGVAVVIEAVHM 204
[148][TOP]
>UniRef100_UPI00004C0E8E PREDICTED: similar to GTP cyclohydrolase I (GTP-CH-I) isoform 1 n=1
Tax=Canis lupus familiaris RepID=UPI00004C0E8E
Length = 249
Score = 122 bits (306), Expect = 2e-26
Identities = 61/170 (35%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGED R+G+ KTP+R A A T+GY++ + +
Sbjct: 55 ERPRSEEDNELNLPNLAAAYSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISD 114
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 115 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 160
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 161 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHM 210
[149][TOP]
>UniRef100_Q4T7V8 Chromosome undetermined SCAF7971, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4T7V8_TETNG
Length = 196
Score = 122 bits (306), Expect = 2e-26
Identities = 62/156 (39%), Positives = 101/156 (64%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E A +L LGED++R+G+ +TP R AKA T+GY + V +++ A+F E+ +
Sbjct: 15 ALETAYTCILRELGEDLDRQGLLRTPLRAAKAMQFLTKGYHETVDDVLNNAIFDEDHDE- 73
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID++S CE L+PF K H+GYIP N++VVGLSKL RV E +
Sbjct: 74 ------------MVIVKDIDMFSLCEHHLVPFFGKVHIGYIP-NKKVVGLSKLARVVEIY 120
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL ++ + + E +QP+GVA++++ H+
Sbjct: 121 SRRLQVQERLTKQVAVGIWEALQPKGVAVVIEAVHM 156
[150][TOP]
>UniRef100_B1WPW8 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. ATCC 51142
RepID=B1WPW8_CYAA5
Length = 239
Score = 122 bits (306), Expect = 2e-26
Identities = 68/166 (40%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+SDE + ++ AV +L +GED REG+ KTP RVA+A T+GY Q++ ++ G
Sbjct: 47 TSDE---STEKMKEAVYTMLEAVGEDPEREGLLKTPKRVAEAMKFLTQGYNQSLEELVNG 103
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGL
Sbjct: 104 AIFDE-------------GHNEMVLVRDINFFSLCEHHMLPFMGQAHVAYIP-NQKVVGL 149
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I A+ E ++P+GVA++++ +H+
Sbjct: 150 SKLARIVEMYSRRLQVQERLTRQIAEAIQEILEPRGVAVVMEASHM 195
[151][TOP]
>UniRef100_C2G1R4 GTP cyclohydrolase I n=1 Tax=Sphingobacterium spiritivorum ATCC
33300 RepID=C2G1R4_9SPHI
Length = 210
Score = 122 bits (306), Expect = 2e-26
Identities = 70/169 (41%), Positives = 101/169 (59%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
K+ + + ++R + Y D+L LGED REG+ KTP RVAKA T GY + +
Sbjct: 17 KIDKYNPLHVDRIATHYT--DILQALGEDPAREGLLKTPERVAKALKYLTHGYDLDPAAV 74
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
++GA+F E+ +V V+DI++YS CE +LPF K HV YIP N +
Sbjct: 75 LKGAMFEED-------------YSQMVVVKDIEVYSLCEHHMLPFFGKAHVAYIP-NGHI 120
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
VGLSK+PRV + FA+RLQ +RL NEI + E + QGVA++++C H+
Sbjct: 121 VGLSKIPRVVDIFARRLQVQERLTNEIRDCIQETLGAQGVAVVMECKHM 169
[152][TOP]
>UniRef100_A4ARF9 GTP cyclohydrolase I n=1 Tax=Flavobacteriales bacterium HTCC2170
RepID=A4ARF9_9FLAO
Length = 199
Score = 122 bits (306), Expect = 2e-26
Identities = 62/144 (43%), Positives = 93/144 (64%)
Frame = +2
Query: 86 LGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGGGVGG 265
+GEDV+REG+ KTP R AKA T+GY+Q+ I++ A+F E
Sbjct: 29 IGEDVSREGLVKTPERAAKAMLFLTQGYQQDAAEILKSAMFQES-------------YNE 75
Query: 266 LVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLAN 445
+V V+DI+LYS CE +LPF K H+ YIP+ Q +VGLSKLPR+ + FA+RLQ +RL
Sbjct: 76 MVIVKDIELYSLCEHHMLPFFGKAHIAYIPNGQ-IVGLSKLPRIVDVFARRLQVQERLTE 134
Query: 446 EICLALHEGIQPQGVAIILQCTHI 517
+I +++ ++PQGVA++++ H+
Sbjct: 135 QILDCINDTLKPQGVAVVIEAAHM 158
[153][TOP]
>UniRef100_A3IMW7 GTP cyclohydrolase I n=1 Tax=Cyanothece sp. CCY0110
RepID=A3IMW7_9CHRO
Length = 239
Score = 122 bits (306), Expect = 2e-26
Identities = 68/166 (40%), Positives = 104/166 (62%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
+SDE + ++ AV +L +GED REG+ KTP RVA+A T+GY Q++ ++ G
Sbjct: 47 TSDE---STEKMKEAVYTMLEAVGEDPEREGLLKTPKRVAEAMKFLTQGYNQSLEELVNG 103
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGL
Sbjct: 104 AIFDE-------------GHNEMVLVRDINFFSLCEHHMLPFMGQAHVAYIP-NQKVVGL 149
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I A+ E ++P+GVA++++ +H+
Sbjct: 150 SKLARIVEMYSRRLQVQERLTRQIAEAIQEILEPRGVAVVMEASHM 195
[154][TOP]
>UniRef100_UPI0000F2B278 PREDICTED: similar to GTP cyclohydrolase I (GTP-CH-I) n=1
Tax=Monodelphis domestica RepID=UPI0000F2B278
Length = 355
Score = 122 bits (305), Expect = 3e-26
Identities = 62/172 (36%), Positives = 107/172 (62%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
+ E+ S ++ +N S+ A +L LGED R+G+ KTP+R A A T+GY++ +
Sbjct: 159 KTERTRSVEDNELNLPSLAGAYSTILRSLGEDPERQGLLKTPWRAATAMQFFTKGYQETI 218
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+I+ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N
Sbjct: 219 SDILNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-N 264
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++++GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 265 KQLLGLSKLARIVEIYSRRLQVQERLTKQIAVAVTEALRPAGVGVVVEATHM 316
[155][TOP]
>UniRef100_Q4RGI4 Chromosome undetermined SCAF15099, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4RGI4_TETNG
Length = 217
Score = 122 bits (305), Expect = 3e-26
Identities = 62/170 (36%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ S+ A +L GLGED R+G+ KTP+R A A T+GY++ +L+
Sbjct: 23 ERTRSVEDNEMSLPSLAAAYTSILKGLGEDPKRQGLLKTPWRAATAMQFFTKGYQEKILD 82
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+P + H+GY+P N+R
Sbjct: 83 VMNDAIFDEDHDE-------------MVIVKDIDIFSMCEHHLVPIFGRVHIGYLP-NKR 128
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E + P GV ++++ TH+
Sbjct: 129 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALHPCGVGVVIEATHM 178
[156][TOP]
>UniRef100_A0M1E0 GTP cyclohydrolase I n=1 Tax=Gramella forsetii KT0803
RepID=A0M1E0_GRAFK
Length = 198
Score = 122 bits (305), Expect = 3e-26
Identities = 66/150 (44%), Positives = 98/150 (65%)
Frame = +2
Query: 68 KDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGH 247
++++ G+GE+ +REGI KTP R AKA T+GY + I++ A+F EE D
Sbjct: 22 QEIIKGVGENPDREGIVKTPERAAKAMQFLTQGYSMDAEEILKKAVF-EESYDE------ 74
Query: 248 GGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQE 427
+V V+DI+LYS CE +LPF K H+ YIP N +++GLSKLPRV + FA+RLQ
Sbjct: 75 ------MVVVKDIELYSLCEHHMLPFFGKAHIAYIP-NGKIIGLSKLPRVVDVFARRLQV 127
Query: 428 PQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RL ++I L+E +QPQGVA++++ H+
Sbjct: 128 QERLTHDILECLNETLQPQGVAVVIEAVHM 157
[157][TOP]
>UniRef100_C5PNR1 GTP cyclohydrolase I n=1 Tax=Sphingobacterium spiritivorum ATCC
33861 RepID=C5PNR1_9SPHI
Length = 210
Score = 122 bits (305), Expect = 3e-26
Identities = 70/169 (41%), Positives = 101/169 (59%)
Frame = +2
Query: 11 KLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNI 190
K+ + + ++R + Y D+L LGED REG+ KTP RVAKA T GY + +
Sbjct: 17 KIDKYNPLHVDRIATHYT--DILQALGEDPAREGLLKTPERVAKALKFLTHGYDLDPAAV 74
Query: 191 IEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRV 370
++GA+F E+ +V V+DI++YS CE +LPF K HV YIP N +
Sbjct: 75 LKGAMFEED-------------YSQMVVVKDIEVYSLCEHHMLPFFGKAHVAYIP-NGHI 120
Query: 371 VGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
VGLSK+PRV + FA+RLQ +RL NEI + E + QGVA++++C H+
Sbjct: 121 VGLSKIPRVVDIFARRLQVQERLTNEIRDCIQETLGAQGVAVVMECKHM 169
[158][TOP]
>UniRef100_Q2JR69 GTP cyclohydrolase 1 n=1 Tax=Synechococcus sp. JA-3-3Ab
RepID=GCH1_SYNJA
Length = 229
Score = 122 bits (305), Expect = 3e-26
Identities = 69/152 (45%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ LL G+GED REG++KTP RV A T GYRQ++ ++I GA+F +EG D
Sbjct: 49 AVETLLRGIGEDPQREGLKKTPERVVAALKFLTSGYRQSLEDLINGAIF-DEGHDE---- 103
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V +RDI L+S CE LLPF K HV YIP Q+VVGLSK+ R+ E +++RL
Sbjct: 104 --------MVLLRDITLFSLCEHHLLPFIGKAHVAYIP-RQKVVGLSKIARIVEMYSRRL 154
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I AL + P GV ++++ TH+
Sbjct: 155 QVQERLTRQIAEALMTMLDPYGVGVVIEATHM 186
[159][TOP]
>UniRef100_B2J1L7 GTP cyclohydrolase 1 n=1 Tax=Nostoc punctiforme PCC 73102
RepID=GCH1_NOSP7
Length = 235
Score = 122 bits (305), Expect = 3e-26
Identities = 64/152 (42%), Positives = 97/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV+ ++LG+GED REG+ KTP RVA+A T GY Q++ ++ A+F E
Sbjct: 54 AVRKIILGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELVNDAIFDE--------- 104
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
G +V VRDI+ +S CE +LPF + HV YIP NQ+VVGLSKL R+ E +++RL
Sbjct: 105 ----GHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIP-NQKVVGLSKLARIVEMYSRRL 159
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ ++P+GVA++++ +H+
Sbjct: 160 QVQERLTRQIAEAIQTILEPRGVAVVMEASHM 191
[160][TOP]
>UniRef100_Q8YN49 GTP cyclohydrolase 1 2 n=1 Tax=Nostoc sp. PCC 7120
RepID=GCH12_ANASP
Length = 216
Score = 122 bits (305), Expect = 3e-26
Identities = 66/171 (38%), Positives = 105/171 (61%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
V L + ++ + + AV+ LL+GLGE+ +REG+ TP RV KA T+GY +++
Sbjct: 16 VSSLSTQQTPTVTEAEMVQAVRTLLIGLGENPDREGLLDTPKRVVKALQFLTKGYNESLD 75
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++ GA+F E+ + +V +RDID++S CE +LP + HV YIP N
Sbjct: 76 ELLNGAVFTEDANE-------------MVLIRDIDIFSSCEHHILPIIGRAHVAYIP-NG 121
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ RV E +A+RLQ +RL +I AL ++PQGVA++++ TH+
Sbjct: 122 KVIGLSKIARVCEMYARRLQVQERLTLQIADALQGLLKPQGVAVVIEATHM 172
[161][TOP]
>UniRef100_Q3MBR5 GTP cyclohydrolase n=1 Tax=Anabaena variabilis ATCC 29413
RepID=Q3MBR5_ANAVT
Length = 216
Score = 121 bits (304), Expect = 3e-26
Identities = 66/171 (38%), Positives = 105/171 (61%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
V L + ++ + + AV+ LL+GLGE+ +REG+ TP RV KA T+GY +++
Sbjct: 16 VSSLSTQQTPTVTEAEMVQAVRTLLIGLGENPDREGLLDTPKRVVKALQFLTKGYNESLD 75
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++ GA+F E+ + +V +RDID++S CE +LP + HV YIP N
Sbjct: 76 ELLNGAVFTEDANE-------------MVLIRDIDIFSSCEHHILPIIGRAHVAYIP-NG 121
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ RV E +A+RLQ +RL +I AL ++PQGVA++++ TH+
Sbjct: 122 KVIGLSKIARVCEMYARRLQVQERLTLQIADALQGLLKPQGVAVVVEATHM 172
[162][TOP]
>UniRef100_A1BF47 GTP cyclohydrolase n=1 Tax=Chlorobium phaeobacteroides DSM 266
RepID=A1BF47_CHLPD
Length = 219
Score = 121 bits (304), Expect = 3e-26
Identities = 72/171 (42%), Positives = 103/171 (60%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E L+ D S S++ AV LL G+GE+ +REG+ KTP RVA++ TRGYRQN
Sbjct: 24 ECLMDGDTASPEEISNLSGAVSMLLQGIGENPDREGLLKTPERVARSMRFLTRGYRQNPE 83
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ A+F E +V VRDID++S CE LLPF K HV YIP
Sbjct: 84 ELLKKAVFTES-------------YDEMVLVRDIDIFSMCEHHLLPFFGKAHVAYIPDG- 129
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++VGLSK+ RV E FA+RLQ +RL +I A+ + + P+GVA++++ H+
Sbjct: 130 KIVGLSKIGRVVEVFARRLQVQERLTQQIRDAIQDVLNPKGVAVVIEAKHL 180
[163][TOP]
>UniRef100_Q26E86 GTP cyclohydrolase I n=1 Tax=Flavobacteria bacterium BBFL7
RepID=Q26E86_9BACT
Length = 198
Score = 121 bits (304), Expect = 3e-26
Identities = 63/155 (40%), Positives = 98/155 (63%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
I+ + ++ +GEDV REG+ KTP R AKA T GY ++ + I++GA+F E+ D
Sbjct: 17 IKNQYQGVIKNIGEDVTREGLIKTPERAAKAMQFLTSGYDKDPVEILKGAMFAEDYND-- 74
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V ++DI+LYS CE +LPF K H+ YIP N +VGLSK+PR+ + FA
Sbjct: 75 -----------MVIIKDIELYSLCEHHMLPFFGKAHIAYIP-NGHIVGLSKIPRIVDVFA 122
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL ++I LH ++P GVA++++ +H+
Sbjct: 123 RRLQVQERLTHDILECLHNTLKPLGVAVVIEASHM 157
[164][TOP]
>UniRef100_B8NIE9 GTP cyclohydrolase I, putative n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8NIE9_ASPFN
Length = 224
Score = 121 bits (304), Expect = 3e-26
Identities = 69/172 (40%), Positives = 106/172 (61%), Gaps = 1/172 (0%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSS-IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
V L + + I+R + + +++ +L +GED NR+G+ KTP R AKA T+GY ++
Sbjct: 25 VVSLCLDEHMKISREARMAASIRSILEDIGEDPNRDGLLKTPERYAKALLFFTKGYEESA 84
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
+I + A+F I H +V VRDI+++S CE L+PF K H+ YIP N
Sbjct: 85 YDIGKDAIF---------NINHNE----IVLVRDIEVFSMCEHHLIPFVGKVHIAYIP-N 130
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE +A+RLQ +RL +I A+ E +QPQGVA++++ H+
Sbjct: 131 GRVLGLSKLARIAEIYARRLQVQERLTKQISQAIEELLQPQGVAVVMESAHM 182
[165][TOP]
>UniRef100_B8MDF1 GTP cyclohydrolase I, putative n=1 Tax=Talaromyces stipitatus ATCC
10500 RepID=B8MDF1_TALSN
Length = 307
Score = 121 bits (304), Expect = 3e-26
Identities = 69/171 (40%), Positives = 106/171 (61%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L S E + R + AVK +L +GED REG+ TP R AKA T+GY +NV
Sbjct: 111 ERLEESPEQNEERVKRLASAVKTILECVGEDPEREGLLGTPERYAKAMLWFTKGYMENVR 170
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ A F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 171 DLVNNATFMEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKIHIGYIP-DR 216
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL +I LA+ E + P+GV ++++ +H+
Sbjct: 217 RVLGLSKLARLAEMFSRRLQVQERLTKQIALAIKEVLNPRGVGVVMESSHL 267
[166][TOP]
>UniRef100_O13774 GTP cyclohydrolase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=GCH1_SCHPO
Length = 235
Score = 121 bits (304), Expect = 3e-26
Identities = 65/155 (41%), Positives = 96/155 (61%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
I A+ +L LGED R+G+ TP R AKA T+GY QN+ +I A+F E+ +
Sbjct: 55 ISNAISTILECLGEDPERQGLLGTPERYAKAMLYFTKGYEQNLTEVINEAVFQEDHEE-- 112
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V VRDID++S CE L+PF K H+GYIP +RV+GLSKL R+A F+
Sbjct: 113 -----------MVIVRDIDVFSLCEHHLVPFIGKIHIGYIP-RKRVLGLSKLARIANMFS 160
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL ++ A+ ++PQGVA++++ TH+
Sbjct: 161 RRLQVQERLTKQVAQAIQAVLKPQGVAVVMEATHM 195
[167][TOP]
>UniRef100_P50141 GTP cyclohydrolase 1 n=1 Tax=Gallus gallus RepID=GCH1_CHICK
Length = 236
Score = 121 bits (304), Expect = 3e-26
Identities = 61/170 (35%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ S+ A +L LGED R+G+ KTP+R A A T+GY++ + +
Sbjct: 42 ERPRSEEDNELSLPSLAAAYTTILRALGEDPERQGLLKTPWRAATAMQFFTKGYQETIAD 101
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V++ID++S CE L+PF K H+GY+P N++
Sbjct: 102 VLNDAIFDEDHDE-------------MVIVKNIDMFSLCEHHLVPFVGKVHIGYLP-NKQ 147
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 148 VLGLSKLARIVEIYSRRLQVQERLTKQIAIAITEALQPAGVGVVIEATHM 197
[168][TOP]
>UniRef100_A3XM03 Putative GTP cyclohydrolase I n=1 Tax=Leeuwenhoekiella blandensis
MED217 RepID=A3XM03_9FLAO
Length = 199
Score = 121 bits (303), Expect = 4e-26
Identities = 64/158 (40%), Positives = 97/158 (61%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ ++ K ++ LGEDV REGI KTP R AKA T GY + I++GA+F E+
Sbjct: 15 KEDVKDRYKAIITDLGEDVTREGIVKTPERAAKAMMYLTSGYDMDASEILKGAMFKEDYR 74
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V V++I+LYS CE LLPF K H+ YIP +VGLSKLPRV +
Sbjct: 75 E-------------MVIVKNIELYSLCEHHLLPFFGKAHIAYIPDGH-IVGLSKLPRVVD 120
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
F++RLQ +RL ++I ++ ++PQGVA++++ +H+
Sbjct: 121 VFSRRLQVQERLTHDILECINNTLKPQGVAVVIEASHM 158
[169][TOP]
>UniRef100_Q7XM20 OSJNBa0084K01.11 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q7XM20_ORYSJ
Length = 451
Score = 121 bits (303), Expect = 4e-26
Identities = 79/201 (39%), Positives = 99/201 (49%), Gaps = 30/201 (14%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGI-------RKTPFRVAKAFFEGT----------------- 160
+E AV+ LLLGLGED REG+ R+ P + +
Sbjct: 1 MEPAVRALLLGLGEDARREGLXEDAQARRQWPVPRRHPMWLNSQEQNPYNSSMHPNPSYI 60
Query: 161 ------RGYRQNVLNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLP 322
+GY Q V +I+ ALFPE G+D SC
Sbjct: 61 MLGLILKGYMQKVRDIVPVALFPEVGVDQRTG-----------------------SCWRN 97
Query: 323 FQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIIL 502
+ I+ HVGY+PS RVVGLSKL RVA+ FAKRLQ PQRLA+E+C ALH IQP GVA+ L
Sbjct: 98 WSIQFHVGYVPSGGRVVGLSKLSRVADVFAKRLQNPQRLASEVCGALHASIQPAGVAVAL 157
Query: 503 QCTHIPFPYKDFDSNHKGWVN 565
QC HIP P +GW++
Sbjct: 158 QCWHIPLPENLKCKTLQGWIS 178
[170][TOP]
>UniRef100_C5KXM9 GTP cyclohydrolase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5KXM9_9ALVE
Length = 259
Score = 121 bits (303), Expect = 4e-26
Identities = 68/167 (40%), Positives = 102/167 (61%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGL-GEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
SS + + SSIE A + +L + GED +R+G++KTP R AKA T+GY +++ I+
Sbjct: 63 SSTKSGSSTSSIESAARRILESIDGEDADRQGLQKTPMRYAKALEFLTKGYSESLEEIVN 122
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E DN +V VRDID++S CE LLPF +GYIP +V+G
Sbjct: 123 DAVFDVEPSDNDE----------MVMVRDIDMFSLCEHHLLPFYGTVDIGYIPRG-KVLG 171
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+ E F++RLQ +R+ +I A+ E I P GVA++++ +H+
Sbjct: 172 LSKLARITEMFSRRLQVQERMTQQIARAVEEAINPMGVAVVIRASHM 218
[171][TOP]
>UniRef100_C5KXM8 GTP cyclohydrolase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5KXM8_9ALVE
Length = 258
Score = 121 bits (303), Expect = 4e-26
Identities = 68/167 (40%), Positives = 102/167 (61%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGL-GEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
SS + + SSIE A + +L + GED +R+G++KTP R AKA T+GY +++ I+
Sbjct: 62 SSTKSGSSTSSIESAARRILESIDGEDADRQGLQKTPMRYAKALEFLTKGYSESLEEIVN 121
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E DN +V VRDID++S CE LLPF +GYIP +V+G
Sbjct: 122 DAVFDVEPSDNDE----------MVMVRDIDMFSLCEHHLLPFYGTVDIGYIPRG-KVLG 170
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+ E F++RLQ +R+ +I A+ E I P GVA++++ +H+
Sbjct: 171 LSKLARITEMFSRRLQVQERMTQQIARAVEEAINPMGVAVVIRASHM 217
[172][TOP]
>UniRef100_Q2UNT8 GTP cyclohydrolase I n=1 Tax=Aspergillus oryzae RepID=Q2UNT8_ASPOR
Length = 237
Score = 121 bits (303), Expect = 4e-26
Identities = 67/164 (40%), Positives = 101/164 (61%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
D S + + +++ +L +GED NR+G+ KTP R AKA T+GY ++ +I + A+
Sbjct: 46 DSKSGTEARMAASIRSILEDIGEDPNRDGLLKTPERYAKALLFFTKGYEESAYDIGKDAI 105
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F I H +V VRDI+++S CE L+PF K H+ YIP N RV+GLSK
Sbjct: 106 F---------NINHNE----IVLVRDIEVFSMCEHHLIPFVGKVHIAYIP-NGRVLGLSK 151
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+AE +A+RLQ +RL +I A+ E +QPQGVA++++ H+
Sbjct: 152 LARIAEIYARRLQVQERLTKQISQAIEELLQPQGVAVVMESAHM 195
[173][TOP]
>UniRef100_Q8KEA8 GTP cyclohydrolase 1 n=1 Tax=Chlorobaculum tepidum RepID=GCH1_CHLTE
Length = 224
Score = 121 bits (303), Expect = 4e-26
Identities = 68/156 (43%), Positives = 96/156 (61%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
S+ AV LL G+GED REG+ TP RVAK+ T+GYRQ+ +++ A+F E
Sbjct: 43 SMTDAVYSLLKGVGEDPEREGLLLTPERVAKSLRFLTKGYRQDPEQLLKKAVFTES---- 98
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID+YS CE +LPF K HV YIP ++VGLSK+PRV E F
Sbjct: 99 ---------YDEMVLVKDIDIYSMCEHHMLPFFGKAHVAYIPDG-KIVGLSKIPRVVEVF 148
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ +RL +I A+ + P+GVA++++ TH+
Sbjct: 149 ARRLQVQERLTQQIRDAIQNVLNPRGVAVVIEATHM 184
[174][TOP]
>UniRef100_UPI00006D5646 PREDICTED: GTP cyclohydrolase 1 (dopa-responsive dystonia) isoform
3 n=1 Tax=Macaca mulatta RepID=UPI00006D5646
Length = 250
Score = 120 bits (302), Expect = 6e-26
Identities = 60/170 (35%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGE+ R+G+ KTP+R A A T+GY++ + +
Sbjct: 56 ERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISD 115
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 116 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 161
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 162 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHM 211
[175][TOP]
>UniRef100_B4SBX8 GTP cyclohydrolase I n=1 Tax=Pelodictyon phaeoclathratiforme BU-1
RepID=B4SBX8_PELPB
Length = 218
Score = 120 bits (302), Expect = 6e-26
Identities = 71/167 (42%), Positives = 100/167 (59%)
Frame = +2
Query: 17 VSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
V +D + IN I AV +L G+GED REG+ KTP RVAK+ T+GYR++ +++
Sbjct: 29 VQNDPMIIN--GISSAVSAMLEGIGEDPQREGLLKTPERVAKSLRFLTKGYREDPEELLK 86
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E +V VRDIDL+S CE +LPF K HV YIP ++VG
Sbjct: 87 KAVFTE-------------AYDEMVLVRDIDLFSMCEHHMLPFFGKAHVAYIPDG-KIVG 132
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL RV E FA+RLQ +RL +I A+ + P+GVA++++ H+
Sbjct: 133 LSKLARVVEVFARRLQVQERLTQQIRDAIQNVLNPKGVAVVIEAKHL 179
[176][TOP]
>UniRef100_Q1VSB5 GTP cyclohydrolase I n=1 Tax=Psychroflexus torquis ATCC 700755
RepID=Q1VSB5_9FLAO
Length = 194
Score = 120 bits (302), Expect = 6e-26
Identities = 64/155 (41%), Positives = 96/155 (61%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
I+ + + +L +GED R GI KTP R AKA T+GY N I+ GA+F E D
Sbjct: 17 IKSSYESILKNIGEDTTRNGIVKTPERAAKAMRFLTQGYNMNPEEILLGAMFEEPYED-- 74
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V ++DI+LYS CE +LPF K HVGYIP N ++VGLSK+PR+ + FA
Sbjct: 75 -----------MVLIKDIELYSLCEHHMLPFFGKVHVGYIP-NGKIVGLSKIPRIVDVFA 122
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL ++I +++ +QP+GV ++++ H+
Sbjct: 123 RRLQVQERLTHDILECINDTLQPKGVGVVIEAQHM 157
[177][TOP]
>UniRef100_C1XV88 GTP cyclohydrolase I n=1 Tax=Meiothermus silvanus DSM 9946
RepID=C1XV88_9DEIN
Length = 201
Score = 120 bits (302), Expect = 6e-26
Identities = 66/155 (42%), Positives = 96/155 (61%)
Frame = +2
Query: 86 LGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGGGVGG 265
+GE+ REG+RKTP R+AKA+ TRGY QN+ II GA+F EG +
Sbjct: 34 IGENPEREGLRKTPERMAKAWAFLTRGYCQNLEEIINGAIFQGEGSE------------- 80
Query: 266 LVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQRLAN 445
+V V+ I+ YS CE LLPF K H+GYIP N +++GLSK R+ + FA+RLQ +RLA
Sbjct: 81 MVVVKGIEFYSMCEHHLLPFFGKVHIGYIP-NGKILGLSKFGRITDMFARRLQVQERLAA 139
Query: 446 EICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
+I A+ E ++PQGV ++++ H+ + + H
Sbjct: 140 QIADAIVEVLEPQGVGVVIEGVHLCMMMRGVEKQH 174
[178][TOP]
>UniRef100_A8J097 GTP cyclohydrolase I n=1 Tax=Chlamydomonas reinhardtii
RepID=A8J097_CHLRE
Length = 209
Score = 120 bits (302), Expect = 6e-26
Identities = 70/147 (47%), Positives = 92/147 (62%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E AV+ L+ GLGED+ REG+R TP RVAKA + T+GY Q+ + + ALF E
Sbjct: 13 MEQAVRVLIHGLGEDLEREGLRDTPKRVAKALLDCTQGYHQDTSSTLGTALFHEP----- 67
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
I H G G +V VRDID S E LLPF +CHV Y P N V+GLSKL R+ + +A
Sbjct: 68 --IVHDGDEG-VVLVRDIDFASTSEETLLPFHGRCHVAYRPKNGVVLGLSKLARLTKQYA 124
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVA 493
KRLQ +RLA E+ AL + ++ G+A
Sbjct: 125 KRLQTQERLAAEVAHALQQSLECYGIA 151
[179][TOP]
>UniRef100_P30793 GTP cyclohydrolase 1 n=2 Tax=Homo sapiens RepID=GCH1_HUMAN
Length = 250
Score = 120 bits (302), Expect = 6e-26
Identities = 60/170 (35%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGE+ R+G+ KTP+R A A T+GY++ + +
Sbjct: 56 ERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISD 115
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 116 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 161
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 162 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHM 211
[180][TOP]
>UniRef100_Q5ZRW0 GTP cyclohydrolase I n=2 Tax=Legionella pneumophila
RepID=Q5ZRW0_LEGPH
Length = 188
Score = 120 bits (301), Expect = 7e-26
Identities = 64/156 (41%), Positives = 94/156 (60%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E +LL LGED+NREG++ TP R A A T+GY +N+ II GALF +
Sbjct: 9 AMEKLYSNLLKELGEDINREGLKDTPGRAANALRYLTKGYNENLDEIINGALFDSD---- 64
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+ +V V+DI+LYS CE LLPF KCHVGY+P +V+GLSK+ R+ + +
Sbjct: 65 ---------MSEMVIVKDIELYSLCEHHLLPFLGKCHVGYLPDG-KVIGLSKIARIVDFY 114
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ +RL EI + +GVA++++ H+
Sbjct: 115 ARRLQIQERLTGEIAHCIESTTGARGVAVVIEAKHL 150
[181][TOP]
>UniRef100_B3QP43 GTP cyclohydrolase I n=1 Tax=Chlorobaculum parvum NCIB 8327
RepID=B3QP43_CHLP8
Length = 230
Score = 120 bits (301), Expect = 7e-26
Identities = 68/152 (44%), Positives = 92/152 (60%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
AV LL G+GED REG+ TP RVAK+ T+GY Q+ ++ ALF E
Sbjct: 53 AVYSLLQGIGEDPEREGLLMTPERVAKSLRFLTKGYEQDPEELLMKALFTES-------- 104
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V V+DIDLYS CE +LPF K HV YIP ++VGLSK+PRV E FA+RL
Sbjct: 105 -----YDEMVLVKDIDLYSMCEHHMLPFFGKAHVAYIPDG-KIVGLSKIPRVVEVFARRL 158
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ + P+GVA++++ TH+
Sbjct: 159 QVQERLTQQIRDAIQNVLNPRGVAVVIEATHM 190
[182][TOP]
>UniRef100_C7R116 GTP cyclohydrolase I n=1 Tax=Jonesia denitrificans DSM 20603
RepID=C7R116_JONDD
Length = 200
Score = 120 bits (301), Expect = 7e-26
Identities = 70/164 (42%), Positives = 100/164 (60%), Gaps = 1/164 (0%)
Frame = +2
Query: 29 EVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALF 208
EV ++R++ AV++LL +GED +REG+R TP RVAKA+ E G RQN
Sbjct: 14 EVDLDRAAA--AVRELLTAVGEDPDREGLRDTPRRVAKAYAEVFAGLRQN---------- 61
Query: 209 PEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ-RVVGLSK 385
P + L+ IGH ++ VRDID+YS CE L+PF HVGYIP RV GLSK
Sbjct: 62 PTDVLNTVFDIGHDE----MILVRDIDVYSTCEHHLVPFHGVAHVGYIPGEDGRVTGLSK 117
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+ + +AKR Q +RL +I +L + + P+GV ++++C H+
Sbjct: 118 LARLVDVYAKRPQVQERLTTQIADSLVDVLHPRGVIVVVECEHL 161
[183][TOP]
>UniRef100_C3YVL1 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3YVL1_BRAFL
Length = 180
Score = 120 bits (301), Expect = 7e-26
Identities = 63/155 (40%), Positives = 96/155 (61%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E A +L +GED R+G+ KTP R A A T+GY++++ ++ A+F E+
Sbjct: 1 MEAAYHTILSSVGEDPARQGLLKTPSRAASALIFFTKGYQEDLQEVVSDAIFDED----- 55
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V VRDI+L+S CE L+PF K VGY+P N++V+GLSK+ R+ E ++
Sbjct: 56 --------TDEMVIVRDIELFSLCEHHLVPFMGKVSVGYLP-NKKVLGLSKIARIVEMYS 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I LAL E IQP GVA++ + TH+
Sbjct: 107 RRLQVQERLTKQIALALSEAIQPAGVAVVCEATHM 141
[184][TOP]
>UniRef100_Q10VY5 GTP cyclohydrolase n=1 Tax=Trichodesmium erythraeum IMS101
RepID=Q10VY5_TRIEI
Length = 212
Score = 120 bits (300), Expect = 1e-25
Identities = 66/163 (40%), Positives = 100/163 (61%)
Frame = +2
Query: 29 EVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALF 208
+ S+ + + AV+ LL+GLGE+ +REG+ TP RV KA T GY Q++ ++ GA+F
Sbjct: 20 QTSVTEAEMVQAVRTLLIGLGENPDREGLLDTPKRVVKALKFLTSGYNQSLDELLNGAVF 79
Query: 209 PEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKL 388
E+ +V VRDIDL+S CE +LP + HV YIP N +V+GLSK+
Sbjct: 80 SED-------------TSEMVLVRDIDLFSSCEHHILPIIGRAHVAYIP-NGKVIGLSKI 125
Query: 389 PRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
R+ E +A+RLQ +RL +I AL ++P GVA++++ TH+
Sbjct: 126 ARICEMYARRLQVQERLTAQIADALQGLLRPLGVAVVVEATHM 168
[185][TOP]
>UniRef100_A8M8H8 GTP cyclohydrolase I n=1 Tax=Salinispora arenicola CNS-205
RepID=A8M8H8_SALAI
Length = 219
Score = 120 bits (300), Expect = 1e-25
Identities = 70/164 (42%), Positives = 101/164 (61%), Gaps = 1/164 (0%)
Frame = +2
Query: 29 EVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALF 208
E SI+ +E AV+++L+ +GED +R+G+++TP RVA+A+ E G R +
Sbjct: 30 EDSIDLVRVENAVREILIAVGEDPDRDGLQQTPARVARAYAELFAGLRVD---------- 79
Query: 209 PEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIP-SNQRVVGLSK 385
P + L T + H LV VRDID+ S CE LLPF+ H+GYIP SN R+ GLSK
Sbjct: 80 PAQVLVTTFEANHDE----LVLVRDIDVMSLCEHHLLPFRGSAHIGYIPGSNGRITGLSK 135
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+ E FA+R Q +RL +I L E +QP+GV ++L+C H+
Sbjct: 136 LARLVEVFARRPQVQERLTAQIADLLMEQLQPRGVIVVLECEHM 179
[186][TOP]
>UniRef100_A4XCS8 GTP cyclohydrolase n=1 Tax=Salinispora tropica CNB-440
RepID=A4XCS8_SALTO
Length = 219
Score = 120 bits (300), Expect = 1e-25
Identities = 67/164 (40%), Positives = 102/164 (62%), Gaps = 1/164 (0%)
Frame = +2
Query: 29 EVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALF 208
E S++ + +E AV+++L+ +GED +R+G+++TP RVA+A+ E G R +
Sbjct: 30 EESVDLARLEKAVREILIAVGEDPDRDGLQQTPARVARAYAELLAGLRVD---------- 79
Query: 209 PEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIP-SNQRVVGLSK 385
P + L T + GH LV VRDID+ S CE LLPF+ H+GYIP +N R+ GLSK
Sbjct: 80 PAQVLTTTFEAGHDE----LVLVRDIDVMSLCEHHLLPFRGSAHIGYIPGANGRITGLSK 135
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+ E FA+R Q +RL ++ L +QP+GV ++L+C H+
Sbjct: 136 LARLVEVFARRPQVQERLTVQVADLLMAQLQPRGVIVVLECEHM 179
[187][TOP]
>UniRef100_A6PUM1 GTP cyclohydrolase I n=1 Tax=Victivallis vadensis ATCC BAA-548
RepID=A6PUM1_9BACT
Length = 179
Score = 120 bits (300), Expect = 1e-25
Identities = 63/166 (37%), Positives = 98/166 (59%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
++ ++D+L+ +GED REG+ TP RV K+ TRGYRQ + ++ GALF E D
Sbjct: 1 MQQQIRDILVEIGEDPEREGLLDTPKRVEKSLKFLTRGYRQTLEEVVNGALFEAESDD-- 58
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V VRDI+ +S CE +LPF KCHVGYIP +++G+SK+ R+ + FA
Sbjct: 59 -----------MVIVRDIEFFSMCEHHMLPFFGKCHVGYIPKG-KILGVSKVARIVDMFA 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
+RLQ +RL +I AL E + +GV ++++ H+ + + H
Sbjct: 107 RRLQIQERLTRQISGALMEILGAEGVGVVMEARHLCMQMRGVEKQH 152
[188][TOP]
>UniRef100_A5KGI1 GTP cyclohydrolase I n=1 Tax=Campylobacter jejuni subsp. jejuni
CG8486 RepID=A5KGI1_CAMJE
Length = 194
Score = 120 bits (300), Expect = 1e-25
Identities = 68/158 (43%), Positives = 94/158 (59%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV KA+ T GY QNV I+ ALF
Sbjct: 6 QKKFEDCVKTMLEIIGENPNREGLIKTPNRVFKAYEFLTSGYTQNVKEILNDALFESSNN 65
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 66 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 111
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E + +GV ++++ H+
Sbjct: 112 VFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHM 149
[189][TOP]
>UniRef100_C1JLF1 GTP cyclohydrolase (Fragment) n=1 Tax=Oryctolagus cuniculus
RepID=C1JLF1_RABIT
Length = 193
Score = 120 bits (300), Expect = 1e-25
Identities = 60/166 (36%), Positives = 102/166 (61%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEG 199
S ++ +N ++ A +L LGED R+G+ KTP+R A A T+GY++ + +++
Sbjct: 3 SEEDNELNLPNLAAAYASILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISDVLND 62
Query: 200 ALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGL 379
A+F E+ + +V V+DID +S CE L+PF K H+GY+P N++V+GL
Sbjct: 63 AIFDEDHDE-------------MVIVKDIDTFSMCEHHLVPFVGKVHIGYLP-NKQVLGL 108
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +++RLQ +RL +I +A+ E + P GV ++++ TH+
Sbjct: 109 SKLARIVEIYSRRLQVQERLTKQIAVAITEALHPAGVGVVVEATHM 154
[190][TOP]
>UniRef100_C5LDD1 GTP cyclohydrolase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LDD1_9ALVE
Length = 259
Score = 120 bits (300), Expect = 1e-25
Identities = 67/167 (40%), Positives = 102/167 (61%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGL-GEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
SS + + SSIE A + +L + GED +R+G++KTP R A+A T+GY +++ I+
Sbjct: 63 SSTKSGSSTSSIESAARRILESIDGEDADRQGLQKTPMRYARALEFLTKGYSESLEEIVN 122
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E DN +V VRDID++S CE LLPF +GYIP +V+G
Sbjct: 123 DAVFDVEPSDNDE----------MVMVRDIDMFSLCEHHLLPFYGTVDIGYIPRG-KVLG 171
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+ E F++RLQ +R+ +I A+ E I P GVA++++ +H+
Sbjct: 172 LSKLARITEMFSRRLQVQERMTQQIARAVEEAINPMGVAVVIRASHM 218
[191][TOP]
>UniRef100_C5LDD0 GTP cyclohydrolase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LDD0_9ALVE
Length = 258
Score = 120 bits (300), Expect = 1e-25
Identities = 67/167 (40%), Positives = 102/167 (61%), Gaps = 1/167 (0%)
Frame = +2
Query: 20 SSDEVSINRSSIEYAVKDLLLGL-GEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIE 196
SS + + SSIE A + +L + GED +R+G++KTP R A+A T+GY +++ I+
Sbjct: 62 SSTKSGSSTSSIESAARRILESIDGEDADRQGLQKTPMRYARALEFLTKGYSESLEEIVN 121
Query: 197 GALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVG 376
A+F E DN +V VRDID++S CE LLPF +GYIP +V+G
Sbjct: 122 DAVFDVEPSDNDE----------MVMVRDIDMFSLCEHHLLPFYGTVDIGYIPRG-KVLG 170
Query: 377 LSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
LSKL R+ E F++RLQ +R+ +I A+ E I P GVA++++ +H+
Sbjct: 171 LSKLARITEMFSRRLQVQERMTQQIARAVEEAINPMGVAVVIRASHM 217
[192][TOP]
>UniRef100_B6QFJ0 GTP cyclohydrolase I, putative n=1 Tax=Penicillium marneffei ATCC
18224 RepID=B6QFJ0_PENMQ
Length = 307
Score = 120 bits (300), Expect = 1e-25
Identities = 67/171 (39%), Positives = 106/171 (61%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
E+L + E + R + AVK +L +GED REG+ TP R A+A T+GY +NV
Sbjct: 111 ERLEETPEQNAERVKKLAGAVKTILECVGEDPEREGLLGTPERYARAMLWFTKGYMENVR 170
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ A F E+ + LV V+DI+++S CE ++PF K H+GYIP ++
Sbjct: 171 DLVNNATFMEDHDE-------------LVIVKDIEVFSLCEHHMVPFTGKIHIGYIP-DR 216
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
RV+GLSKL R+AE F++RLQ +RL +I LA+ E + P+GV ++++ +H+
Sbjct: 217 RVLGLSKLARLAEMFSRRLQVQERLTKQIALAIKEVLNPRGVGVVMESSHL 267
[193][TOP]
>UniRef100_P51594 GTP cyclohydrolase 1 n=5 Tax=Campylobacter jejuni RepID=GCH1_CAMJE
Length = 190
Score = 120 bits (300), Expect = 1e-25
Identities = 68/158 (43%), Positives = 94/158 (59%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV KA+ T GY QNV I+ ALF
Sbjct: 2 QKKFEDCVKTMLEIIGENPNREGLIKTPNRVFKAYEFLTSGYTQNVKEILNDALFESSNN 61
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 62 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 107
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E + +GV ++++ H+
Sbjct: 108 VFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHM 145
[194][TOP]
>UniRef100_A8FJZ5 GTP cyclohydrolase 1 n=1 Tax=Campylobacter jejuni subsp. jejuni
81116 RepID=GCH1_CAMJ8
Length = 190
Score = 120 bits (300), Expect = 1e-25
Identities = 68/158 (43%), Positives = 94/158 (59%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV KA+ T GY QNV I+ ALF
Sbjct: 2 QKKFEDCVKTILEIIGENPNREGLIKTPNRVFKAYEFLTSGYTQNVKEILNDALFESSNN 61
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 62 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 107
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E + +GV ++++ H+
Sbjct: 108 VFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHM 145
[195][TOP]
>UniRef100_Q4C6P8 GTP cyclohydrolase I n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4C6P8_CROWT
Length = 218
Score = 119 bits (299), Expect = 1e-25
Identities = 66/172 (38%), Positives = 102/172 (59%)
Frame = +2
Query: 2 EVEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNV 181
++ L ++ ++ + AV+ LLLGLGED +REG++ TP RV KA T GY Q++
Sbjct: 17 KLPSLTTTQRPLVSDEEMRQAVRTLLLGLGEDPDREGLKDTPKRVVKALKFLTSGYHQSL 76
Query: 182 LNIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSN 361
++ A+F E + +V VRDIDL+S CE +LP + HV YIP
Sbjct: 77 DELLNEAVFHESANE-------------MVLVRDIDLFSSCEHHILPIIGRAHVAYIPDG 123
Query: 362 QRVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSK+ R+ E + +RLQ +RL +I AL +QP+GVA++++ TH+
Sbjct: 124 -KVIGLSKIARICEMYGRRLQVQERLTGQIADALQGLLQPKGVAVVVEATHM 174
[196][TOP]
>UniRef100_A6DCP8 GTP cyclohydrolase I n=1 Tax=Caminibacter mediatlanticus TB-2
RepID=A6DCP8_9PROT
Length = 192
Score = 119 bits (299), Expect = 1e-25
Identities = 67/173 (38%), Positives = 105/173 (60%)
Frame = +2
Query: 32 VSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP 211
+S++ +E A K +L +GE+ NR+G+ KTP RVAK+F E GY ++ ++ ALF
Sbjct: 1 MSVDLEKLETAAKMILEAIGENPNRDGLIKTPKRVAKSFEEICSGYFKDPKEVLNDALF- 59
Query: 212 EEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLP 391
D+TN +V VRDI+ YS CE +LPF + HV YIP +++VVGLSK+P
Sbjct: 60 ----DSTNN--------EMVVVRDIEFYSMCEHHILPFFGRVHVAYIP-DKKVVGLSKIP 106
Query: 392 RVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
R+ E FA+RLQ ++L +I A+ E ++P+GV +++ H+ + + H
Sbjct: 107 RMVEVFARRLQIQEQLTEQIADAIMEVVKPKGVGVVIHARHMCMEMRGVKTKH 159
[197][TOP]
>UniRef100_A3UBT5 GTP cyclohydrolase I n=1 Tax=Croceibacter atlanticus HTCC2559
RepID=A3UBT5_9FLAO
Length = 199
Score = 119 bits (299), Expect = 1e-25
Identities = 69/165 (41%), Positives = 101/165 (61%)
Frame = +2
Query: 23 SDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGA 202
+DE+ SSI + LGEDV REGI KTP R AKA T GY + I++GA
Sbjct: 15 TDEIKSQFSSI-------ITNLGEDVAREGIVKTPERAAKAMQFLTSGYDIDAAEILKGA 67
Query: 203 LFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLS 382
+F E+ D +V V++I+LYS CE +LPF K H+ YIP N +VGLS
Sbjct: 68 MFKEDYND-------------MVVVKNIELYSLCEHHMLPFFGKAHIAYIP-NGHIVGLS 113
Query: 383 KLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
KLPRV + FA+RLQ +RL ++I +++ ++P+GVA++++ +H+
Sbjct: 114 KLPRVVDVFARRLQVQERLTHDILECINDTLKPKGVAVVIEASHM 158
[198][TOP]
>UniRef100_A2TP10 GTP cyclohydrolase I n=1 Tax=Dokdonia donghaensis MED134
RepID=A2TP10_9FLAO
Length = 198
Score = 119 bits (299), Expect = 1e-25
Identities = 63/148 (42%), Positives = 94/148 (63%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
++ LGED +REGI KTP R AKA T GY + I++GA+F E+ D
Sbjct: 24 IIKSLGEDTSREGIVKTPERAAKAMQYLTSGYEMDAAAILKGAMFKEDYDD--------- 74
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V V++I+LYS CE +LPF K H+ YIP N +VGLSKLPR+ + FA+RLQ +
Sbjct: 75 ----MVIVKNIELYSLCEHHMLPFFGKAHIAYIP-NGHIVGLSKLPRIVDVFARRLQVQE 129
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL ++I ++ +QP+GVA++++ +H+
Sbjct: 130 RLTHDILECINTTLQPKGVAVVIEASHM 157
[199][TOP]
>UniRef100_Q2GYY2 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2GYY2_CHAGB
Length = 233
Score = 119 bits (299), Expect = 1e-25
Identities = 66/170 (38%), Positives = 103/170 (60%), Gaps = 1/170 (0%)
Frame = +2
Query: 11 KLVSSDEVSINR-SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
++ S E S+ R + AV+ +L +GE+ +R G+ TP R AKA T+GY QN+
Sbjct: 75 RIEESPEQSVKRLGKLGDAVRTMLECIGENPDRPGVLNTPERYAKAMMFLTQGYGQNIHE 134
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
I+ A+F E G +V V+DID++S CE +LPF K H+ YIP +
Sbjct: 135 IVNNAIFHE-------------GHHEMVIVKDIDIFSICEHHMLPFIGKMHIAYIPYHS- 180
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+G+SKLPR+AE F++RLQ +RL ++ + E +QPQGVA++++ +H+
Sbjct: 181 VIGISKLPRIAEMFSRRLQIQERLTKDVANTIMEVLQPQGVAVVMEASHL 230
[200][TOP]
>UniRef100_Q19980 GTP cyclohydrolase 1 n=1 Tax=Caenorhabditis elegans
RepID=GCH1_CAEEL
Length = 223
Score = 119 bits (299), Expect = 1e-25
Identities = 59/152 (38%), Positives = 97/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A + ++ +GED+NR+G+ KTP R AKA T+GY + ++ A+F E+ +
Sbjct: 46 AYQSIIQHVGEDINRQGLLKTPERAAKAMMAFTKGYDDQLDELLNEAVFDEDHDE----- 100
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V V+DI+++S CE L+PF K H+GYIP N++V+GLSKL R+ E F++RL
Sbjct: 101 --------MVIVKDIEMFSLCEHHLVPFMGKVHIGYIP-NKKVLGLSKLARIVEMFSRRL 151
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ + +QP GVA++++ +H+
Sbjct: 152 QVQERLTKQIATAMVQAVQPSGVAVVIEASHM 183
[201][TOP]
>UniRef100_Q5X1C9 GTP cyclohydrolase I n=2 Tax=Legionella pneumophila
RepID=Q5X1C9_LEGPA
Length = 179
Score = 119 bits (298), Expect = 2e-25
Identities = 64/155 (41%), Positives = 93/155 (60%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E +LL LGED+NREG++ TP R A A T+GY +N+ II GALF +
Sbjct: 1 MEKLYSNLLKELGEDINREGLKDTPGRAANALRYLTKGYNENLDEIINGALFDSD----- 55
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+ +V V+DI+LYS CE LLPF KCHVGY+P +V+GLSK+ R+ + +A
Sbjct: 56 --------MSEMVIVKDIELYSLCEHHLLPFLGKCHVGYLPDG-KVIGLSKIARIVDFYA 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL EI + +GVA++++ H+
Sbjct: 107 RRLQIQERLTGEIAHCIESITGARGVAVVIEAKHL 141
[202][TOP]
>UniRef100_A4CLH3 GTP cyclohydrolase I n=1 Tax=Robiginitalea biformata HTCC2501
RepID=A4CLH3_9FLAO
Length = 198
Score = 119 bits (298), Expect = 2e-25
Identities = 61/148 (41%), Positives = 94/148 (63%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
+L +GED REG+ KTP R AKA T+GYRQ+ + I++GA+F E +
Sbjct: 24 ILREIGEDPAREGLLKTPERAAKAMLFLTQGYRQDAVEILKGAMFRESYSE--------- 74
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V ++DI++YS CE +LPF K HV YIP +VGLSK+PRV + FA+RLQ +
Sbjct: 75 ----MVLIKDIEVYSLCEHHMLPFYGKAHVAYIPDGH-IVGLSKIPRVVDVFARRLQVQE 129
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL ++I ++ ++P+GVA++++ H+
Sbjct: 130 RLTDDILECINTTLKPRGVAVVIEAAHM 157
[203][TOP]
>UniRef100_P51596 GTP cyclohydrolase 1 (Fragment) n=1 Tax=Oncorhynchus mykiss
RepID=GCH1_ONCMY
Length = 225
Score = 119 bits (298), Expect = 2e-25
Identities = 59/170 (34%), Positives = 106/170 (62%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ ++ S+ A ++ GLG+D R+G+ KTP+R A A T+GY++ +++
Sbjct: 64 ERTRSIEDNEMSLPSLAAAYTTIIRGLGKDPQRQGLLKTPWRAATAMQFFTKGYQEKIID 123
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+ E+ + +V V+DID++S CE L+P + H+GY+P N+R
Sbjct: 124 VLNDAILDEDHDE-------------MVIVKDIDMFSMCEHHLVPIFGRVHIGYLP-NKR 169
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
V+GLSKL R+ E +++RLQ +RL +I +A+ E +QP GV ++++ TH+
Sbjct: 170 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHM 219
[204][TOP]
>UniRef100_C7PRB8 GTP cyclohydrolase I n=1 Tax=Chitinophaga pinensis DSM 2588
RepID=C7PRB8_CHIPD
Length = 195
Score = 119 bits (297), Expect = 2e-25
Identities = 71/170 (41%), Positives = 100/170 (58%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
++ V+SD + +SSI LGEDV REG++KTP RVAKA T GY+ +
Sbjct: 10 DEKVTSDLIQHYKSSIAL--------LGEDVEREGLQKTPERVAKAMQFLTEGYQMDAKA 61
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
I+EGA F E + +V V+DI+LYS CE +LPF K H+ YIP N
Sbjct: 62 ILEGAKFTETYSE-------------MVIVKDIELYSLCEHHMLPFFGKAHIAYIP-NGY 107
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ GLSKL RV + FA+RLQ +RL ++I A+ E +QP GV ++++ H+
Sbjct: 108 ITGLSKLARVVDVFARRLQVQERLTHQILDAIQETLQPLGVGVVIEAQHL 157
[205][TOP]
>UniRef100_C0BJL5 GTP cyclohydrolase I n=1 Tax=Flavobacteria bacterium MS024-2A
RepID=C0BJL5_9BACT
Length = 197
Score = 119 bits (297), Expect = 2e-25
Identities = 66/155 (42%), Positives = 94/155 (60%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
I+ +D+L LGED REG+ KTP R AKA T GY Q+ I++ A+F E
Sbjct: 16 IQTNYEDILHLLGEDKAREGLLKTPERAAKAMRFLTEGYEQDPKKILKSAMFEET----- 70
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V V+DI+LYS CE +LPF K H+ YIP N +VGLSK+PRV + FA
Sbjct: 71 --------YNEMVIVKDIELYSLCEHHMLPFFGKAHIAYIP-NGHIVGLSKIPRVVDVFA 121
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I ++E +QP GVA++++ +H+
Sbjct: 122 RRLQVQERLTEQILDCINETLQPTGVAVVIEASHM 156
[206][TOP]
>UniRef100_A8X8K8 C. briggsae CBR-CAT-4 protein n=1 Tax=Caenorhabditis briggsae
RepID=A8X8K8_CAEBR
Length = 228
Score = 119 bits (297), Expect = 2e-25
Identities = 59/156 (37%), Positives = 99/156 (63%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
S+ A + ++ +GED++R+G+ KTP R AKA T+GY + ++ A+F E+ +
Sbjct: 47 SMRNAYESIIQHVGEDIHRQGLLKTPERAAKAMMAFTKGYDDQLDELLNEAVFDEDHDE- 105
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DI+++S CE L+PF K H+GYIP N++V+GLSKL R+ E F
Sbjct: 106 ------------MVIVKDIEMFSLCEHHLVPFMGKVHIGYIP-NKKVLGLSKLARIVEMF 152
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I A+ + +QP GVA++++ +H+
Sbjct: 153 SRRLQVQERLTKQIATAMVQAVQPSGVAVVIEASHM 188
[207][TOP]
>UniRef100_A7H1R1 GTP cyclohydrolase 1 n=1 Tax=Campylobacter jejuni subsp. doylei
269.97 RepID=GCH1_CAMJD
Length = 190
Score = 119 bits (297), Expect = 2e-25
Identities = 69/158 (43%), Positives = 93/158 (58%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV KA+ T GY QNV I+ ALF
Sbjct: 2 QKKFEDCVKTMLEIIGENPNREGLIKTPNRVFKAYEFLTSGYTQNVKEILNDALFESSNN 61
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 62 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 107
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E +GV +I++ H+
Sbjct: 108 VFARRLQIQEQLTEQIAQALMENADAKGVGVIIEARHM 145
[208][TOP]
>UniRef100_C3XZ05 Putative uncharacterized protein n=2 Tax=Branchiostoma floridae
RepID=C3XZ05_BRAFL
Length = 180
Score = 118 bits (296), Expect = 3e-25
Identities = 63/155 (40%), Positives = 97/155 (62%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E A +L +GE+ R+G+ KTP R AKA T+GY++++ I+ A+F E+
Sbjct: 1 MEAAYHTILSSVGEEPARQGLLKTPSRAAKALMFFTKGYQEDLQGILNDAVFDED----- 55
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
+V VRDI+++S CE L+PF K VGY+P N++V+GLSK+ R+ E ++
Sbjct: 56 --------TDEMVIVRDIEMFSMCEHHLVPFIGKVSVGYLP-NKKVLGLSKIARIVEMYS 106
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL +I LAL E IQP GVA++ + TH+
Sbjct: 107 RRLQVQERLTKQIALALSEAIQPAGVAVVCEATHM 141
[209][TOP]
>UniRef100_UPI00017B4446 UPI00017B4446 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4446
Length = 174
Score = 118 bits (296), Expect = 3e-25
Identities = 61/151 (40%), Positives = 94/151 (62%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
S +E + KD+L LGED REG+++TP R AKA T+GY ++V I+ A+F E +
Sbjct: 37 SQMEKSYKDILTELGEDATREGLQRTPLRAAKAMQFLTKGYNESVKEILNDAIFDENHQE 96
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+++S CE L+PF K H+ Y+P N++VVGLSKL R+ E
Sbjct: 97 -------------VVIVKDIEMFSLCEHHLVPFFGKAHIAYLP-NKKVVGLSKLARIVEV 142
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAII 499
+++R Q +RL +I A+ E ++P GVA++
Sbjct: 143 YSRRFQVQERLTKQIASAISEALEPAGVAVV 173
[210][TOP]
>UniRef100_Q481T3 GTP cyclohydrolase I n=1 Tax=Colwellia psychrerythraea 34H
RepID=Q481T3_COLP3
Length = 181
Score = 118 bits (296), Expect = 3e-25
Identities = 63/156 (40%), Positives = 96/156 (61%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
SIE ++++ +GED+NREG+ TP R AKA T+GY+QN+ +++ GALF E +
Sbjct: 2 SIENNYREIIATIGEDINREGLIDTPKRAAKAMEFLTQGYQQNINDVVNGALFESEADE- 60
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V++I+LYS CE +LPF KCH+ Y PS +V+GLSK R+ + +
Sbjct: 61 ------------MVVVKNIELYSMCEHHMLPFIGKCHIAYFPSG-KVLGLSKFARIVDMY 107
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ + LA EI L++ E GV +I++ H+
Sbjct: 108 ARRLQIQENLAREIALSIQEITGSIGVGVIIEAQHL 143
[211][TOP]
>UniRef100_B5VY61 GTP cyclohydrolase I n=1 Tax=Arthrospira maxima CS-328
RepID=B5VY61_SPIMA
Length = 215
Score = 118 bits (296), Expect = 3e-25
Identities = 65/160 (40%), Positives = 102/160 (63%)
Frame = +2
Query: 38 INRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEE 217
++ + AV+ LLLGLGE+ +REG++ TP RV KA T GY Q++ ++ GA+F E
Sbjct: 26 VSEEEMRQAVRTLLLGLGENPDREGLKDTPKRVVKALKFLTSGYHQSLDELLNGAVFHE- 84
Query: 218 GLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRV 397
NT++ +V VRDID++S CE +LP + HV YIP +V+GLSK+ R+
Sbjct: 85 ---NTDE---------MVLVRDIDIFSSCEHHILPILGRAHVAYIPDG-KVIGLSKVARI 131
Query: 398 AEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
E +A+RLQ +RL +I AL ++P+GVA++++ +H+
Sbjct: 132 CEMYARRLQVQERLTAQIADALQGLLKPKGVAVVVEASHM 171
[212][TOP]
>UniRef100_Q5HWX4 GTP cyclohydrolase 1 n=1 Tax=Campylobacter jejuni RM1221
RepID=GCH1_CAMJR
Length = 190
Score = 118 bits (296), Expect = 3e-25
Identities = 67/158 (42%), Positives = 94/158 (59%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV KA+ GY QNV +I+ ALF
Sbjct: 2 QKKFEDCVKTILEIIGENPNREGLIKTPNRVFKAYEFLASGYTQNVKDILNDALFESSNN 61
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 62 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 107
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E + +GV ++++ H+
Sbjct: 108 VFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHM 145
[213][TOP]
>UniRef100_A1VXS2 GTP cyclohydrolase 1 n=2 Tax=Campylobacter jejuni subsp. jejuni
RepID=GCH1_CAMJJ
Length = 190
Score = 118 bits (296), Expect = 3e-25
Identities = 67/158 (42%), Positives = 93/158 (58%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E VK +L +GE+ NREG+ KTP RV K + T GY QNV I+ ALF
Sbjct: 2 QKKFEDCVKTMLEIIGENPNREGLIKTPNRVFKTYEFLTSGYTQNVKEILNDALFESSNN 61
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
+ +V VRDI+ YS CE LLPF + HV YIP N++VVGLSK+PR+ E
Sbjct: 62 E-------------MVLVRDIEFYSLCEHHLLPFFGRAHVAYIP-NKKVVGLSKIPRLVE 107
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ ++L +I AL E + +GV ++++ H+
Sbjct: 108 VFARRLQIQEQLTEQIAQALMENVDAKGVGVVIEARHM 145
[214][TOP]
>UniRef100_B3EIA8 GTP cyclohydrolase I n=1 Tax=Chlorobium limicola DSM 245
RepID=B3EIA8_CHLL2
Length = 219
Score = 118 bits (295), Expect = 4e-25
Identities = 69/171 (40%), Positives = 103/171 (60%)
Frame = +2
Query: 5 VEKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVL 184
+ +L +D +++R I AV +L G+GED REG+ KTP RVA++ TRGYRQ+
Sbjct: 26 LHELQDTDTEALSR--IADAVSSMLDGVGEDPEREGLVKTPERVARSMRFLTRGYRQDPE 83
Query: 185 NIIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
+++ A+F E +V VRDID++S CE LLPF K HV YIP
Sbjct: 84 EVLKKAVFTE-------------AYDEMVLVRDIDIFSMCEHHLLPFFGKAHVAYIPDG- 129
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++VGLSK+ RV E +A+RLQ +RL +I A+ + P+GVA++++ H+
Sbjct: 130 KIVGLSKIARVVEVYARRLQVQERLTQQIRDAIQNVLNPRGVAVVIEARHM 180
[215][TOP]
>UniRef100_C4Q4I6 GTP cyclohydrolase I n=1 Tax=Schistosoma mansoni RepID=C4Q4I6_SCHMA
Length = 303
Score = 118 bits (295), Expect = 4e-25
Identities = 61/152 (40%), Positives = 98/152 (64%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A ++L+ +GE+ NR+G+ KTP R AK+ T+GY + V +I+ A+F E +
Sbjct: 126 AYHNILVAIGENPNRQGLLKTPQRAAKSILYFTKGYEECVNDILNDAIFDEHHDE----- 180
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
LV V+DI+++S CE L+PF +GYIP N++++GLSKL R+ E +++RL
Sbjct: 181 --------LVIVKDIEMFSMCEHHLIPFIGHVSIGYIP-NKKILGLSKLARIVEIYSRRL 231
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL EI +AL+E I+P+GV +I++ TH+
Sbjct: 232 QVQERLTKEIAIALNESIKPKGVGVIIEATHM 263
[216][TOP]
>UniRef100_UPI0000E46177 PREDICTED: similar to GTP cyclohydrolase I precursor (GTP-CH-I) n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E46177
Length = 273
Score = 117 bits (294), Expect = 5e-25
Identities = 59/152 (38%), Positives = 97/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A + ++ G+GED NR+G++KTP R AKA T+GY + + +++ A+F E+ +
Sbjct: 97 AYRSIIRGVGEDPNRQGLKKTPDRAAKAMMFFTKGYEEKIEDVLNDAIFDEDHDE----- 151
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V V+DI+++S CE L+PF K VGY+P N+RV+GLSK+ R+ E +++RL
Sbjct: 152 --------MVVVKDIEMFSLCEHHLVPFIGKVSVGYLP-NKRVLGLSKVARLVEIYSRRL 202
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I LA+ E I P GV ++++ H+
Sbjct: 203 QVQERLTKQIALAVTEAIAPAGVGVVIEAVHM 234
[217][TOP]
>UniRef100_UPI00005A173C PREDICTED: similar to GTP cyclohydrolase I (GTP-CH-I) isoform 2 n=1
Tax=Canis lupus familiaris RepID=UPI00005A173C
Length = 250
Score = 117 bits (294), Expect = 5e-25
Identities = 61/171 (35%), Positives = 106/171 (61%), Gaps = 1/171 (0%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGED R+G+ KTP+R A A T+GY++ + +
Sbjct: 55 ERPRSEEDNELNLPNLAAAYSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISD 114
Query: 188 -IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ 364
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N+
Sbjct: 115 DVLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NK 160
Query: 365 RVVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 161 QVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHM 211
[218][TOP]
>UniRef100_Q1IPJ1 GTP cyclohydrolase n=1 Tax=Candidatus Koribacter versatilis
Ellin345 RepID=Q1IPJ1_ACIBL
Length = 199
Score = 117 bits (294), Expect = 5e-25
Identities = 67/179 (37%), Positives = 99/179 (55%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
+ ++ +S E V +LL +GED REG+ +TP R AKA T+GY ++ ++ GAL
Sbjct: 6 EPTTLTSASNEELVAELLQRIGEDPKREGLLRTPERYAKALKFLTKGYDEDPETVLNGAL 65
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSK 385
F +V V+DI+++S CE LLPF K H+ YIP N +V+GLSK
Sbjct: 66 FTVT-------------YDEMVIVKDIEMFSLCEHHLLPFFGKVHIAYIP-NGKVIGLSK 111
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNHKGWV 562
LPR+ E FA+RLQ +RL EI + I+P GV +I++ H+ + + H V
Sbjct: 112 LPRLVEVFARRLQVQERLTTEIAQTIERVIEPLGVGVIIEARHLCMMMRGVEKQHSSTV 170
[219][TOP]
>UniRef100_C1A6G2 GTP cyclohydrolase I n=1 Tax=Gemmatimonas aurantiaca T-27
RepID=C1A6G2_GEMAT
Length = 222
Score = 117 bits (294), Expect = 5e-25
Identities = 68/157 (43%), Positives = 97/157 (61%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
S E V+ L +GED R+G+ KTP RVA++ TRGY + ++I ALF E D
Sbjct: 37 SEYETMVRRQLELIGEDPTRDGLLKTPGRVARSMAWLTRGYDLDPRSVIGDALFAE---D 93
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+ N +V VRDI++YS CE +LPF K H+ YIP N ++VGLSKLPRV E
Sbjct: 94 HEN----------MVMVRDIEMYSMCEHHMLPFFGKVHIAYIP-NGKIVGLSKLPRVVEV 142
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
FA+RLQ +RL +I A+ + +QP+GV ++++ H+
Sbjct: 143 FARRLQVQERLGEQIANAIVDVLQPKGVGVVIEAVHL 179
[220][TOP]
>UniRef100_UPI0000D9BC2B PREDICTED: GTP cyclohydrolase 1 (dopa-responsive dystonia) isoform
2 n=1 Tax=Macaca mulatta RepID=UPI0000D9BC2B
Length = 213
Score = 117 bits (293), Expect = 6e-25
Identities = 59/168 (35%), Positives = 104/168 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGE+ R+G+ KTP+R A A T+GY++ + +
Sbjct: 56 ERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISD 115
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 116 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 161
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCT 511
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ T
Sbjct: 162 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEAT 209
[221][TOP]
>UniRef100_Q4SEZ7 Chromosome 1 SCAF14609, whole genome shotgun sequence n=1
Tax=Tetraodon nigroviridis RepID=Q4SEZ7_TETNG
Length = 263
Score = 117 bits (293), Expect = 6e-25
Identities = 61/150 (40%), Positives = 93/150 (62%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
S +E + KD+L LGED REG+++TP R AKA T+GY ++V I+ A+F E +
Sbjct: 37 SQMEKSYKDILTELGEDATREGLQRTPLRAAKAMQFLTKGYNESVKEILNDAIFDENHQE 96
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+++S CE L+PF K H+ Y+P N++VVGLSKL R+ E
Sbjct: 97 -------------VVIVKDIEMFSLCEHHLVPFFGKAHIAYLP-NKKVVGLSKLARIVEV 142
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAI 496
+++R Q +RL +I A+ E ++P GVA+
Sbjct: 143 YSRRFQVQERLTKQIASAISEALEPAGVAV 172
[222][TOP]
>UniRef100_C7PWZ1 GTP cyclohydrolase I n=1 Tax=Catenulispora acidiphila DSM 44928
RepID=C7PWZ1_CATAD
Length = 234
Score = 117 bits (293), Expect = 6e-25
Identities = 66/155 (42%), Positives = 97/155 (62%), Gaps = 1/155 (0%)
Frame = +2
Query: 56 EYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTN 235
E AV++LLL +GED +REG+++TP RV++A+ E G Q PE+ L T
Sbjct: 55 ERAVRELLLAVGEDPDREGLKETPARVSRAYREIFAGLHQG----------PEDVLTTTF 104
Query: 236 KIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPS-NQRVVGLSKLPRVAEAFA 412
+GH +V VRDI++YS CE L+PF HVGYIPS + R+ GLSKL R+ + +A
Sbjct: 105 DLGHDE----MVLVRDIEVYSTCEHHLVPFHGVAHVGYIPSVDGRITGLSKLARLVDVYA 160
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
KR Q +RL +I AL ++P+GV ++++C H+
Sbjct: 161 KRPQVQERLTTQIADALVRILEPRGVIVVVECEHL 195
[223][TOP]
>UniRef100_C0V9G4 GTP cyclohydrolase I n=1 Tax=Xylanimonas cellulosilytica DSM 15894
RepID=C0V9G4_9MICO
Length = 202
Score = 117 bits (293), Expect = 6e-25
Identities = 65/161 (40%), Positives = 102/161 (63%), Gaps = 1/161 (0%)
Frame = +2
Query: 38 INRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEE 217
++ + E AV++LLL +GE+ +REG+R+TP RVA+A+ E G RQ PE+
Sbjct: 17 VDLARAEAAVRELLLAVGENPDREGLRETPARVARAYQEVFAGLRQE----------PED 66
Query: 218 GLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV-GLSKLPR 394
L T IGH +V V+DI++YS CE L+PF HVGYIPS V+ GLSK+ R
Sbjct: 67 VLTTTFDIGH----EEMVLVKDIEVYSTCEHHLVPFHGVAHVGYIPSTDGVITGLSKIAR 122
Query: 395 VAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ + +A+R Q +RL +++ AL + ++P+GV ++++C H+
Sbjct: 123 LVDVYARRPQVQERLTSQVADALVKILRPRGVIVVIECEHL 163
[224][TOP]
>UniRef100_A9DXR7 GTP cyclohydrolase I n=1 Tax=Kordia algicida OT-1
RepID=A9DXR7_9FLAO
Length = 198
Score = 117 bits (293), Expect = 6e-25
Identities = 61/150 (40%), Positives = 94/150 (62%)
Frame = +2
Query: 68 KDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGH 247
K ++ LGED REG+ KTP R AKA T+GY + I++GA+F E+
Sbjct: 22 KAIIEELGEDTTREGLLKTPERAAKAMQFLTQGYDMDPAEILKGAMFAED---------- 71
Query: 248 GGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQE 427
+V V+DI+LYS CE +LPF K H+ YIP N +VGLSKLPR+ + F++RLQ
Sbjct: 72 ---YNEMVIVKDIELYSLCEHHILPFFGKAHIAYIP-NGHIVGLSKLPRIVDVFSRRLQV 127
Query: 428 PQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RL ++I ++ ++P+GVA++++ +H+
Sbjct: 128 QERLTHDILECINNTLKPKGVAVVIEASHM 157
[225][TOP]
>UniRef100_B4LMQ4 GJ20545 n=1 Tax=Drosophila virilis RepID=B4LMQ4_DROVI
Length = 270
Score = 117 bits (293), Expect = 6e-25
Identities = 60/148 (40%), Positives = 97/148 (65%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
LL GLGE+ +R+G+ KTP R AKA T+GY QN+ +++ GA+F E+ +
Sbjct: 97 LLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQNLEDVLNGAVFDEDHDE--------- 147
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V V+DI+++S CE L+PF K +GY+P N +++GLSKL R+ E F++RLQ +
Sbjct: 148 ----MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPCN-KILGLSKLARIVEIFSRRLQVQE 202
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL +I +A+ + +QP GVA++++ H+
Sbjct: 203 RLTKQIAVAVTQAVQPAGVAVVVEGVHM 230
[226][TOP]
>UniRef100_B4KNC3 GI20812 n=1 Tax=Drosophila mojavensis RepID=B4KNC3_DROMO
Length = 274
Score = 117 bits (293), Expect = 6e-25
Identities = 60/148 (40%), Positives = 97/148 (65%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
LL GLGE+ +R+G+ KTP R AKA T+GY QN+ +++ GA+F E+ +
Sbjct: 101 LLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQNLEDVLNGAVFDEDHDE--------- 151
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V V+DI+++S CE L+PF K +GY+P N +++GLSKL R+ E F++RLQ +
Sbjct: 152 ----MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPCN-KILGLSKLARIVEIFSRRLQVQE 206
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL +I +A+ + +QP GVA++++ H+
Sbjct: 207 RLTKQIAVAVTQAVQPAGVAVVVEGVHM 234
[227][TOP]
>UniRef100_B4J6Q1 GH20729 n=1 Tax=Drosophila grimshawi RepID=B4J6Q1_DROGR
Length = 337
Score = 117 bits (293), Expect = 6e-25
Identities = 60/148 (40%), Positives = 97/148 (65%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
LL GLGE+ +R+G+ KTP R AKA T+GY QN+ +++ GA+F E+ +
Sbjct: 164 LLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQNLEDVLNGAVFDEDHDE--------- 214
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V V+DI+++S CE L+PF K +GY+P N +++GLSKL R+ E F++RLQ +
Sbjct: 215 ----MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPCN-KILGLSKLARIVEIFSRRLQVQE 269
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL +I +A+ + +QP GVA++++ H+
Sbjct: 270 RLTKQIAVAVTQAVQPAGVAVVVEGVHM 297
[228][TOP]
>UniRef100_P30793-2 Isoform GCH-2 of GTP cyclohydrolase 1 n=2 Tax=Homo sapiens
RepID=P30793-2
Length = 213
Score = 117 bits (293), Expect = 6e-25
Identities = 59/168 (35%), Positives = 104/168 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGE+ R+G+ KTP+R A A T+GY++ + +
Sbjct: 56 ERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISD 115
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 116 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 161
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCT 511
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ T
Sbjct: 162 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEAT 209
[229][TOP]
>UniRef100_P30793-4 Isoform GCH-4 of GTP cyclohydrolase 1 n=1 Tax=Homo sapiens
RepID=P30793-4
Length = 233
Score = 117 bits (293), Expect = 6e-25
Identities = 59/168 (35%), Positives = 104/168 (61%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
E+ S ++ +N ++ A +L LGE+ R+G+ KTP+R A A T+GY++ + +
Sbjct: 56 ERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISD 115
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
++ A+F E+ + +V V+DID++S CE L+PF K H+GY+P N++
Sbjct: 116 VLNDAIFDEDHDE-------------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQ 161
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCT 511
V+GLSKL R+ E +++RLQ +RL +I +A+ E ++P GV ++++ T
Sbjct: 162 VLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEAT 209
[230][TOP]
>UniRef100_UPI0000382827 COG0302: GTP cyclohydrolase I n=1 Tax=Magnetospirillum
magnetotacticum MS-1 RepID=UPI0000382827
Length = 233
Score = 117 bits (292), Expect = 8e-25
Identities = 65/166 (39%), Positives = 102/166 (61%), Gaps = 1/166 (0%)
Frame = +2
Query: 23 SDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGA 202
+D ++ E AV++LLL +GED +REG+R+TP RVA+A+ E G RQ ++
Sbjct: 27 ADVPPYDQDRAEAAVRELLLAVGEDPDREGLRETPARVARAYREIFAGLRQEAADV---- 82
Query: 203 LFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPS-NQRVVGL 379
L T +GH +V V+DI++YS CE L+PF HVGYIP+ + R+ GL
Sbjct: 83 ------LTTTFDLGHEE----MVLVKDIEVYSTCEHHLVPFHGVAHVGYIPNVDGRITGL 132
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ E +A+R Q +RL +++ AL E ++P+G ++++C H+
Sbjct: 133 SKLARLVEVYARRPQVQERLTSQVADALVEHLKPRGAIVVVECEHL 178
[231][TOP]
>UniRef100_Q117H2 GTP cyclohydrolase n=1 Tax=Trichodesmium erythraeum IMS101
RepID=Q117H2_TRIEI
Length = 243
Score = 117 bits (292), Expect = 8e-25
Identities = 67/170 (39%), Positives = 102/170 (60%)
Frame = +2
Query: 8 EKLVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLN 187
+KL + D + ++ AV+ +LL + E+ REG+ TP R A+A T GY Q++
Sbjct: 48 QKLSTED----SNERMKEAVRTILLSVEENPEREGLLNTPKRFAEAMQFLTSGYSQSLEE 103
Query: 188 IIEGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQR 367
I+ GA+F E G +V VRDI+ +S CE +LPF K H+ YIP NQ+
Sbjct: 104 IVNGAIFDE-------------GHNEMVLVRDINFFSLCEHHMLPFMGKAHIAYIP-NQK 149
Query: 368 VVGLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
VVGLSKL RV + +++RLQ +RL +I A+ ++P+GVA++++ THI
Sbjct: 150 VVGLSKLARVVDMYSRRLQVQERLNRQIAEAIQTILEPKGVAVVIEATHI 199
[232][TOP]
>UniRef100_C5C888 GTP cyclohydrolase I n=1 Tax=Micrococcus luteus NCTC 2665
RepID=C5C888_MICLC
Length = 206
Score = 117 bits (292), Expect = 8e-25
Identities = 67/165 (40%), Positives = 97/165 (58%), Gaps = 1/165 (0%)
Frame = +2
Query: 26 DEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGAL 205
D +++R IE AV+++LL +GED +REG+ TP RVAKA+ E G Q+
Sbjct: 17 DSTAVDRPRIEAAVREILLAIGEDPDREGLADTPARVAKAYAEFFAGLHQS--------- 67
Query: 206 FPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ-RVVGLS 382
P++ L T I H LV V+DI YS CE L+PF H+GYIPS + RV GLS
Sbjct: 68 -PDQVLGTTFDIAH----EELVLVKDIPFYSTCEHHLVPFHGAAHIGYIPSAEGRVTGLS 122
Query: 383 KLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
KL R+ E +A+R Q +RL ++ AL E + P+G ++++ H+
Sbjct: 123 KLARLVELYARRPQVQERLTTQVVEALMEHLAPRGAIVVVEAEHM 167
[233][TOP]
>UniRef100_B9L6X5 GTP cyclohydrolase I n=1 Tax=Nautilia profundicola AmH
RepID=B9L6X5_NAUPA
Length = 192
Score = 117 bits (292), Expect = 8e-25
Identities = 65/173 (37%), Positives = 105/173 (60%)
Frame = +2
Query: 32 VSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFP 211
+S++ +E A K +L +GEDV+R+G+ KTP RVAK+F GY ++ ++ ALF
Sbjct: 1 MSVDLEKLELAAKMILEAIGEDVDRDGLVKTPRRVAKSFEYICSGYFKDPKEVLNDALF- 59
Query: 212 EEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLP 391
++TN +V VR+I+ YS CE +LPF + HV YIP +++VVGLSK+P
Sbjct: 60 ----ESTNN--------EMVVVRNIEFYSMCEHHILPFFGRVHVAYIP-DKKVVGLSKIP 106
Query: 392 RVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
R+ FA+RLQ ++L +I A+ E +QP+GV +++ H+ + ++ H
Sbjct: 107 RMVNVFARRLQIQEQLTEQIADAIMEVVQPKGVGVVIHARHMCMEMRGVETKH 159
[234][TOP]
>UniRef100_C4RE48 GTP cyclohydrolase I n=1 Tax=Micromonospora sp. ATCC 39149
RepID=C4RE48_9ACTO
Length = 196
Score = 117 bits (292), Expect = 8e-25
Identities = 67/164 (40%), Positives = 100/164 (60%), Gaps = 1/164 (0%)
Frame = +2
Query: 29 EVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALF 208
E +++ + IE AV+++L+ +GED +R+G+ KTP RVA+A+ E G R +
Sbjct: 7 EEAVDLARIEKAVREILIAVGEDPDRDGLVKTPARVARAYAELFAGLRVD---------- 56
Query: 209 PEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPS-NQRVVGLSK 385
P + L T + H LV VRDIDL S CE LLPF+ H+GYIP + R+ GLSK
Sbjct: 57 PAQVLSTTFEANHEE----LVLVRDIDLMSLCEHHLLPFRGSAHIGYIPGPDGRITGLSK 112
Query: 386 LPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
L R+ E FA+R Q +RL ++I L + + P+GV ++L+C H+
Sbjct: 113 LARLVEVFARRPQVQERLTSQIADLLMDKLAPRGVVVVLECEHM 156
[235][TOP]
>UniRef100_C3BW12 GTP cyclohydrolase 1 n=1 Tax=Bacillus pseudomycoides DSM 12442
RepID=C3BW12_9BACI
Length = 195
Score = 117 bits (292), Expect = 8e-25
Identities = 68/168 (40%), Positives = 94/168 (55%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L + V I+ IE AVK +L +GED+NREGI +TP RVAK + E +G QN
Sbjct: 3 LKTIQSVEIDTDKIEVAVKMILEAIGEDINREGILETPKRVAKMYKEVFQGLGQN----- 57
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
P E L H LV V+DI YS CE L+PF + H+GYIP+N +V
Sbjct: 58 -----PSEHLLKIFNENHEE----LVLVKDIPFYSMCEHHLVPFFGRAHIGYIPNNGKVT 108
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
GLSKL R E KR Q +R+ NE+ + E ++P+GV ++++ H+
Sbjct: 109 GLSKLARALETICKRPQLQERITNELANVIFETLEPKGVIVVIEAEHM 156
[236][TOP]
>UniRef100_C3AVK5 GTP cyclohydrolase 1 n=2 Tax=Bacillus mycoides RepID=C3AVK5_BACMY
Length = 195
Score = 117 bits (292), Expect = 8e-25
Identities = 68/168 (40%), Positives = 94/168 (55%)
Frame = +2
Query: 14 LVSSDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNII 193
L + V I+ IE AVK +L +GED+NREGI +TP RVAK + E +G QN
Sbjct: 3 LKTIQSVEIDTDKIEVAVKMILEAIGEDINREGILETPKRVAKMYKEVFQGLGQN----- 57
Query: 194 EGALFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVV 373
P E L H LV V+DI YS CE L+PF + H+GYIP+N +V
Sbjct: 58 -----PSEHLLKIFNENHEE----LVLVKDIPFYSMCEHHLVPFFGRAHIGYIPNNGKVT 108
Query: 374 GLSKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
GLSKL R E KR Q +R+ NE+ + E ++P+GV ++++ H+
Sbjct: 109 GLSKLARALETICKRPQLQERITNELANVIFETLEPKGVIVVIEAEHM 156
[237][TOP]
>UniRef100_Q607T5 GTP cyclohydrolase 1 n=1 Tax=Methylococcus capsulatus
RepID=GCH1_METCA
Length = 185
Score = 117 bits (292), Expect = 8e-25
Identities = 62/157 (39%), Positives = 94/157 (59%)
Frame = +2
Query: 47 SSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLD 226
S +E L+ +GEDV+REG+ TP R A AF GY Q++ +++ A+F + D
Sbjct: 3 SVMETLFSQLIQEIGEDVSREGLVDTPKRAASAFRFLNSGYHQSLDHVLNNAVFEADSED 62
Query: 227 NTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEA 406
+V V+DI+LYS CE LLPF KCHVGY+P +V+GLSK+ R+ E
Sbjct: 63 -------------MVIVKDIELYSLCEHHLLPFIGKCHVGYLPQG-KVIGLSKIARIVEM 108
Query: 407 FAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+A+RLQ +RL +I A+ + P+GVA++++ H+
Sbjct: 109 YARRLQIQERLTKQIADAIQTAVNPRGVAVVVEAKHL 145
[238][TOP]
>UniRef100_UPI000069DF28 UPI000069DF28 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069DF28
Length = 177
Score = 116 bits (291), Expect = 1e-24
Identities = 62/152 (40%), Positives = 96/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A +L L E+ REG+ TP R AKA T+GY++ V +++ A+F E+ +
Sbjct: 1 AYSTILRELAENPEREGLLLTPSRAAKAMQFLTKGYKETVYDVMNNAVFDEDHDE----- 55
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V V+DID++S CE L+PF K H+GYIP N++VVGLSKL R+AE +++RL
Sbjct: 56 --------IVIVKDIDIFSLCEHHLVPFFGKVHIGYIP-NKKVVGLSKLARIAEIYSRRL 106
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I A+ E +QP GVA++++ +H+
Sbjct: 107 QVQERLTKQIAFAILEALQPIGVAVVMEASHM 138
[239][TOP]
>UniRef100_C2A0B1 GTP cyclohydrolase I n=1 Tax=Sulfurospirillum deleyianum DSM 6946
RepID=C2A0B1_SULDE
Length = 191
Score = 116 bits (291), Expect = 1e-24
Identities = 65/169 (38%), Positives = 97/169 (57%)
Frame = +2
Query: 44 RSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGL 223
+ E AVK +L +GE+ REG+ KTP RV KA+ T+GY Q+ ++ ALF
Sbjct: 4 KEEFENAVKTMLEIIGENTQREGLLKTPSRVFKAYEYMTQGYHQSPTEVLNEALFES--- 60
Query: 224 DNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAE 403
DN +V ++DI+ YS CE LLP + HV YIP N +VVGLSK+PR+ +
Sbjct: 61 DNNQ----------MVLIKDIEFYSMCEHHLLPIIGRAHVAYIP-NGKVVGLSKIPRMVD 109
Query: 404 AFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHIPFPYKDFDSNH 550
FA+RLQ ++L +I A+ + I P+GV +++Q H+ + + H
Sbjct: 110 IFARRLQIQEQLTEQIAKAIDDVIAPKGVGVVIQARHMCMEMRGVEKTH 158
[240][TOP]
>UniRef100_B5HIA5 GTP cyclohydrolase I n=1 Tax=Streptomyces pristinaespiralis ATCC
25486 RepID=B5HIA5_STRPR
Length = 201
Score = 116 bits (291), Expect = 1e-24
Identities = 65/155 (41%), Positives = 98/155 (63%), Gaps = 1/155 (0%)
Frame = +2
Query: 56 EYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTN 235
E AV++LL+ +GED +REG+R+TP RVA+A+ E G Q PE+ L T
Sbjct: 22 ENAVRELLIAVGEDPDREGLRETPARVARAYREIFAGLWQQ----------PEDVLTTTF 71
Query: 236 KIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQ-RVVGLSKLPRVAEAFA 412
IGH +V V+DI++YS CE L+PF+ HVGYIPS ++ GLSKL R+ + FA
Sbjct: 72 DIGHDE----MVLVKDIEVYSTCEHHLVPFRGVAHVGYIPSTTGKITGLSKLARLVDVFA 127
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+R Q +R+ +I +L E ++P+GV ++++C H+
Sbjct: 128 RRPQVQERMTTQIADSLMEILEPRGVIVVVECEHM 162
[241][TOP]
>UniRef100_B7G4N1 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7G4N1_PHATR
Length = 186
Score = 116 bits (291), Expect = 1e-24
Identities = 62/151 (41%), Positives = 95/151 (62%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A K +L +GED +REG+ KTP R AKA +GY + ++ GA+F E +
Sbjct: 4 ACKTILECIGEDPHREGLLKTPLRWAKALLYMCQGYDKRPEDVTNGAVFHENHSE----- 58
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V VR+ID++S CE ++PF + H+GYIP N +++GLSKL R+AE +A+RL
Sbjct: 59 --------MVVVRNIDIHSLCEHHMVPFTGRVHIGYIP-NGKILGLSKLARIAELYARRL 109
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTH 514
Q +RL +I A+ E ++P GVA++++CTH
Sbjct: 110 QVQERLTRQIADAIVETVEPLGVAVVVECTH 140
[242][TOP]
>UniRef100_B4P9G3 GE12177 n=1 Tax=Drosophila yakuba RepID=B4P9G3_DROYA
Length = 271
Score = 116 bits (291), Expect = 1e-24
Identities = 60/148 (40%), Positives = 97/148 (65%)
Frame = +2
Query: 74 LLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIGHGG 253
LL GLGE+ +R+G+ KTP R AKA T+GY Q++ +++ GA+F E+ +
Sbjct: 98 LLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQSLEDVLNGAVFDEDHDE--------- 148
Query: 254 GVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQEPQ 433
+V V+DI+++S CE L+PF K +GY+P N +++GLSKL R+ E FA+RLQ +
Sbjct: 149 ----MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPCN-KILGLSKLARIVEIFARRLQVQE 203
Query: 434 RLANEICLALHEGIQPQGVAIILQCTHI 517
RL +I +A+ + +QP GVA++++ H+
Sbjct: 204 RLTKQIAVAVTQAVQPAGVAVVVEGVHM 231
[243][TOP]
>UniRef100_Q8IZH9 GTP cyclohydrolase I type IV (Fragment) n=1 Tax=Homo sapiens
RepID=Q8IZH9_HUMAN
Length = 177
Score = 116 bits (291), Expect = 1e-24
Identities = 57/152 (37%), Positives = 97/152 (63%)
Frame = +2
Query: 62 AVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKI 241
A +L LGE+ R+G+ KTP+R A A T+GY++ + +++ A+F E+ +
Sbjct: 1 AYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDE----- 55
Query: 242 GHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRL 421
+V V+DID++S CE L+PF K H+GY+P N++V+GLSKL R+ E +++RL
Sbjct: 56 --------MVIVKDIDMFSMCEHHLVPFVGKVHIGYLP-NKQVLGLSKLARIVEIYSRRL 106
Query: 422 QEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
Q +RL +I +A+ E ++P GV ++++ TH+
Sbjct: 107 QVQERLTKQIAVAITEALRPAGVGVVVEATHM 138
[244][TOP]
>UniRef100_Q3ATN0 GTP cyclohydrolase 1 n=1 Tax=Chlorobium chlorochromatii CaD3
RepID=GCH1_CHLCH
Length = 223
Score = 116 bits (291), Expect = 1e-24
Identities = 65/156 (41%), Positives = 94/156 (60%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
++E AV +L +GED REG+ KTP RVA++ T+GY +N +++ ALF E
Sbjct: 43 NLESAVYTMLQNVGEDPQREGLLKTPERVARSMRFLTKGYHENPEELLQKALFTES---- 98
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V VRDIDL+S CE +LPF K HV YIP ++VGLSKL RV E F
Sbjct: 99 ---------YDEMVLVRDIDLFSMCEHHMLPFFGKAHVAYIPDG-KIVGLSKLARVVEVF 148
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
++RLQ +RL +I A+ + P+GVA++++ H+
Sbjct: 149 SRRLQVQERLTQQIRDAIQNVLNPKGVAVVIEAKHL 184
[245][TOP]
>UniRef100_Q47ZY9 GTP cyclohydrolase I n=1 Tax=Colwellia psychrerythraea 34H
RepID=Q47ZY9_COLP3
Length = 182
Score = 116 bits (290), Expect = 1e-24
Identities = 62/156 (39%), Positives = 96/156 (61%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
+IE +++L +GED+NR G+ TP R AKA T+GY+QN+ +++ GALF + +
Sbjct: 2 TIENNYREILATIGEDINRGGLLDTPKRAAKAMEFLTQGYKQNIDDVVNGALFESDADE- 60
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V++I+LYS CE +LPF KCH+ YIP N +V+GLSK R+ + +
Sbjct: 61 ------------MVVVKNIELYSMCEHHMLPFIGKCHIAYIP-NGKVLGLSKFARIVDMY 107
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ + LA EI L++ E GV +I++ H+
Sbjct: 108 ARRLQIQENLAREIALSIQEITGSIGVGVIIEAQHL 143
[246][TOP]
>UniRef100_C2MB05 GTP cyclohydrolase I n=1 Tax=Porphyromonas uenonis 60-3
RepID=C2MB05_9PORP
Length = 207
Score = 116 bits (290), Expect = 1e-24
Identities = 64/151 (42%), Positives = 90/151 (59%)
Frame = +2
Query: 65 VKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIG 244
V LL LGED REG+ KTP RV+KA T+GY+++ L I+ A F E+
Sbjct: 32 VNALLTELGEDPTREGLLKTPERVSKALHFLTKGYQEDPLAILRAATFREDYQQ------ 85
Query: 245 HGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQ 424
+V VRDID YS CE +LPF K HVGYIP N+ + GLSK+PR+ + FA+RLQ
Sbjct: 86 -------MVIVRDIDFYSLCEHHMLPFFGKVHVGYIP-NKYITGLSKIPRIVDVFARRLQ 137
Query: 425 EPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RL +I + + + P GV ++++ H+
Sbjct: 138 VQERLTTQIKDCIQQALSPLGVIVVIEAQHM 168
[247][TOP]
>UniRef100_UPI0000587DDF PREDICTED: similar to GTP cyclohydrolase I n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000587DDF
Length = 209
Score = 115 bits (289), Expect = 2e-24
Identities = 61/155 (39%), Positives = 93/155 (60%)
Frame = +2
Query: 53 IEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNT 232
+E A + +L +GED +RE ++KTP R AKA TRGY+ + +++ GA+F +
Sbjct: 31 LELAYRSVLRAVGEDPDREDLKKTPHRAAKAMMFFTRGYQDQIEDVLNGAIFEADH---- 86
Query: 233 NKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFA 412
G+V VR I+++S CE LLP K VGY+P V+GLSK+ R+ E ++
Sbjct: 87 ---------DGMVVVRGIEMFSLCEHHLLPIVGKVSVGYLPKKS-VLGLSKIARIVEMYS 136
Query: 413 KRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+RLQ +RL EI LA+ + I P GV +I++ TH+
Sbjct: 137 RRLQAQERLTKEIALAVVQAIDPAGVGVIVEATHM 171
[248][TOP]
>UniRef100_A9KFF3 GTP cyclohydrolase 1 n=5 Tax=Coxiella burnetii RepID=GCH1_COXBN
Length = 184
Score = 115 bits (289), Expect = 2e-24
Identities = 60/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 65 VKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDNTNKIG 244
VK +L+ LGED NREG+R TP R KA T+GY + + ++++ A+F + G+D
Sbjct: 9 VKAILIALGEDPNREGLRDTPKRYEKALEHLTKGYHEKLPSVVKKAVF-QSGMDE----- 62
Query: 245 HGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAFAKRLQ 424
+V ++DI+LYS CE LLPF +CHV Y+PS +++G+SKL R+ + FAKRLQ
Sbjct: 63 -------MVILKDIELYSLCEHHLLPFIGRCHVAYLPSG-KIIGISKLARIVDMFAKRLQ 114
Query: 425 EPQRLANEICLALHEGIQPQGVAIILQCTHI 517
+ L +I A+ + +GV +I++ H+
Sbjct: 115 VQENLTKQIAEAILTATEAKGVGVIIEAKHL 145
[249][TOP]
>UniRef100_C4DLB0 GTP cyclohydrolase I n=1 Tax=Stackebrandtia nassauensis DSM 44728
RepID=C4DLB0_9ACTO
Length = 214
Score = 115 bits (289), Expect = 2e-24
Identities = 63/166 (37%), Positives = 103/166 (62%), Gaps = 1/166 (0%)
Frame = +2
Query: 23 SDEVSINRSSIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGA 202
S + ++ IE AV+++L +GED +REG+ KTP RVA+A+ E G R + +++
Sbjct: 21 SVDTQVDLKRIETAVREILYAIGEDPDREGLAKTPGRVARAYAELFAGLRVDPAQVLK-T 79
Query: 203 LFPEEGLDNTNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIP-SNQRVVGL 379
+F E+ + L+ VRDI+++S+CE LLPF H+GYIP ++ R+ GL
Sbjct: 80 VFSEDHDE-------------LIVVRDIEVFSFCEHHLLPFTGVAHIGYIPGAHGRITGL 126
Query: 380 SKLPRVAEAFAKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
SKL R+ EA+A+R Q +RL ++I LHE ++ GV ++++C H+
Sbjct: 127 SKLARLVEAYARRPQVQERLTSQIADQLHETLEANGVIVVVECEHM 172
[250][TOP]
>UniRef100_A4SF37 GTP cyclohydrolase 1 n=1 Tax=Chlorobium phaeovibrioides DSM 265
RepID=GCH1_PROVI
Length = 223
Score = 115 bits (289), Expect = 2e-24
Identities = 65/156 (41%), Positives = 95/156 (60%)
Frame = +2
Query: 50 SIEYAVKDLLLGLGEDVNREGIRKTPFRVAKAFFEGTRGYRQNVLNIIEGALFPEEGLDN 229
S+ +V LL G+GED REG+ KTP RVA++ TRGYRQ+ +++ A+F E
Sbjct: 43 SMSESVYTLLEGVGEDPEREGLLKTPERVARSLAFLTRGYRQDPEEMLKKAVFTES---- 98
Query: 230 TNKIGHGGGVGGLVFVRDIDLYSYCESCLLPFQIKCHVGYIPSNQRVVGLSKLPRVAEAF 409
+V V+DID++S CE +LPF K HV YIP ++VGLSKL RV E F
Sbjct: 99 ---------YDEMVLVKDIDIFSMCEHHMLPFFGKAHVAYIPDG-KIVGLSKLARVVEVF 148
Query: 410 AKRLQEPQRLANEICLALHEGIQPQGVAIILQCTHI 517
A+RLQ +RL +I A+ + + P+GV ++++ H+
Sbjct: 149 ARRLQVQERLTQQIRDAIQDVLHPKGVGVVIEAKHM 184