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[1][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 93.6 bits (231), Expect = 6e-18
Identities = 59/158 (37%), Positives = 85/158 (53%), Gaps = 6/158 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD-PGETVTDKVAFYNKQN 178
++ RL + LN +LK+LMPGL+AK FRT+NAS+TL + L + G V +KV Y N
Sbjct: 722 DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHAN 781
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H M +L + E ++ELK L++ KG AK GA P
Sbjct: 782 KEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAK-GADGEP 840
Query: 359 -----PVEVTQYMPVKPEILESMTADEKAQERKRAADL 457
P + + + +E M D+K +E +A L
Sbjct: 841 KRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVAL 878
[2][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 93.2 bits (230), Expect = 8e-18
Identities = 59/152 (38%), Positives = 80/152 (52%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNK 181
++ RL T LN +LK +MP L+AK FRT+NAS+TL LQ GET + +A Y + NK
Sbjct: 429 DLFERLDTTKLNLHLKGIMPSLTAKVFRTYNASITLDNLLQDTTGETTIEIIADYQRANK 488
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPP 361
VA LCNH R++ GH M +LE + E ++EL+ L + KG K S
Sbjct: 489 QVAILCNHQRSVSKGHSAQMERLEGKMQELEEQLEELETDLDRAKKGKPPLK---DSEGK 545
Query: 362 VEVTQYMPVKPEILESMTADEKAQERKRAADL 457
V+ Q PE LE A K + K D+
Sbjct: 546 VKRNQ----TPEALEKKIAATKQKIDKMRLDM 573
[3][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 92.8 bits (229), Expect = 1e-17
Identities = 58/147 (39%), Positives = 77/147 (52%), Gaps = 1/147 (0%)
Frame = +2
Query: 17 LSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAE 193
L + LN +LK+LMPGL+AK FRT+NAS+TL + L + G V +KV Y NK VA
Sbjct: 709 LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAI 768
Query: 194 LCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT 373
+CNH RT+ H M +L + E A V+ELK L++ KG K+ A P
Sbjct: 769 ICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKR-- 826
Query: 374 QYMPVKPEILESMTADEKAQERKRAAD 454
+ PE LE A A+ K D
Sbjct: 827 ---NLNPESLEKKIAQTNAKIEKMERD 850
[4][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 92.4 bits (228), Expect = 1e-17
Identities = 47/107 (43%), Positives = 66/107 (61%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNK 181
++ RL T LN +LK +MPGL+AK FRT+NAS+TL LQ GET + +A Y + NK
Sbjct: 299 DLFERLDTTKLNLHLKGIMPGLTAKVFRTYNASITLDTLLQDTRGETTIEIIADYQRANK 358
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
VA LCNH R++ GH M +LE + E ++EL+ L + +G
Sbjct: 359 EVAILCNHQRSVSKGHSAQMERLELKMQELEEQLEELETDLDRAKRG 405
[5][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 91.3 bits (225), Expect = 3e-17
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD-PGETVTDKVAFYNKQN 178
++ RL + LN +LK+LMPGL+AK FRT+NAS+TL + L + G V +KV Y N
Sbjct: 723 DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQHAN 782
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H M +L + E ++ELK L++ K GK GA P
Sbjct: 783 KEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKK-GKPPSKGADGKP 841
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
+ PE LE A A+ K D
Sbjct: 842 K------RNLNPEALERKMAQINAKIEKMERD 867
[6][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 90.9 bits (224), Expect = 4e-17
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD-PGETVTDKVAFYNKQN 178
++ RL + LN +LK+LMPGL+AK FRT+NAS+TL + L + G V +KV Y + N
Sbjct: 722 DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRAN 781
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H M +L + E ++ELK L++ K GK G P
Sbjct: 782 KEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKK-GKPPSKGDDGEP 840
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
+ PE LE A A+ K D
Sbjct: 841 K------RNLNPEALERKIAQTNAKIEKMERD 866
[7][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 89.7 bits (221), Expect = 9e-17
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
++ +L + LN +LK+LMPGL+AK FRT+NAS+TL E L + G +K+ Y N
Sbjct: 679 DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHAN 738
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH R++ H M +L + E + ELK LA+ KG P
Sbjct: 739 KEVAIICNHQRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKG----------KP 788
Query: 359 PVEVTQYMPVK---PEILESMTADEKAQERKRAADL 457
P++ + P K PE+LE A + K D+
Sbjct: 789 PLKDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDM 824
[8][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 89.7 bits (221), Expect = 9e-17
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
++ +L + LN +LK+LMPGL+AK FRT+NAS+TL E L + G +K+ Y N
Sbjct: 585 DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHAN 644
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH R++ H M +L + E + ELK LA+ KG P
Sbjct: 645 KEVAIICNHQRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKG----------KP 694
Query: 359 PVEVTQYMPVK---PEILESMTADEKAQERKRAADL 457
P++ + P K PE+LE A + K D+
Sbjct: 695 PLKDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDM 730
[9][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 89.4 bits (220), Expect = 1e-16
Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 307 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 366
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H + KL R E +KELK L + KG P
Sbjct: 367 KEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG----------KP 416
Query: 359 PVEVT---QYMPVKPEILESMTADEKAQERKRAADL 457
P+E + + ++P E A + A+ K D+
Sbjct: 417 PLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDM 452
[10][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 89.4 bits (220), Expect = 1e-16
Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 189 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 248
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H + KL R E +KELK L + KG P
Sbjct: 249 KEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG----------KP 298
Query: 359 PVEVT---QYMPVKPEILESMTADEKAQERKRAADL 457
P+E + + ++P E A + A+ K D+
Sbjct: 299 PLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDM 334
[11][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 89.4 bits (220), Expect = 1e-16
Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 63 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 122
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H + KL R E +KELK L + KG P
Sbjct: 123 KEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG----------KP 172
Query: 359 PVEVT---QYMPVKPEILESMTADEKAQERKRAADL 457
P+E + + ++P E A + A+ K D+
Sbjct: 173 PLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDM 208
[12][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 89.4 bits (220), Expect = 1e-16
Identities = 49/108 (45%), Positives = 66/108 (61%), Gaps = 1/108 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ +L T LN +LK+LMPGL+AK FRT+NAS+TL E L + + V +KV Y + N
Sbjct: 687 DLFDKLDTTKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKVVIYQRAN 746
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
K VA +CNH RT+ H M KL + E A +KELK L + KG
Sbjct: 747 KEVAIICNHQRTISKSHGAQMSKLIEKIEELKATLKELKTDLDRAKKG 794
[13][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 89.4 bits (220), Expect = 1e-16
Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 709 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 768
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H + KL R E +KELK L + KG P
Sbjct: 769 KEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG----------KP 818
Query: 359 PVEVT---QYMPVKPEILESMTADEKAQERKRAADL 457
P+E + + ++P E A + A+ K D+
Sbjct: 819 PLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDM 854
[14][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 89.0 bits (219), Expect = 2e-16
Identities = 54/152 (35%), Positives = 78/152 (51%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD-PGETVTDKVAFYNKQN 178
N+ +L LN +LK+LMPGLSAK FRT+NAS+TL E L + G V+ KVA Y N
Sbjct: 705 NLFDKLDTCKLNAHLKELMPGLSAKVFRTYNASITLDEMLNKETKGGDVSQKVAVYQHAN 764
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH R++ H M +L+ + + +++ELK L++ KG K +
Sbjct: 765 KEVAIICNHQRSVSKSHSTQMMRLDEKINKLKNFIEELKTDLSRAKKGKPPLKGSDGKTK 824
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
+ PE +E A + K D
Sbjct: 825 -------RNMNPEAIEKKIAQTNVKIEKMERD 849
[15][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 88.6 bits (218), Expect = 2e-16
Identities = 59/157 (37%), Positives = 85/157 (54%), Gaps = 8/157 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ TS+N YL +LM GLSAK FRTFNAS+TL + LQ +P + V K+ YN+
Sbjct: 300 DLFDRLTTTSVNKYLSELMEGLSAKVFRTFNASLTLQDQLQKLTNPEDNVNAKILSYNRA 359
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGL------AKWNKGGKGAK 337
N+ VA LCNH RT P + M L+ + ++ VKE K+ L AK +K K
Sbjct: 360 NRAVAILCNHQRTAPKTFEKSMSNLQLKISDKKKTVKEAKKELKALRVKAKESKSESNNK 419
Query: 338 AGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRA 448
A V+ + K E+ TA +K + ++ A
Sbjct: 420 AVEKKKAQVQRLEEQLFKLEV----TATDKEENKEIA 452
[16][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 88.2 bits (217), Expect = 3e-16
Identities = 54/153 (35%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ +L LN +LK+LMPGL+AK FRTFNAS+TL + L D + +K+ Y N
Sbjct: 683 DLFDKLDTNKLNAHLKELMPGLTAKVFRTFNASITLDDKLNKDTKDGDAAEKIVVYQHAN 742
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH R++ H M KL + E +KELK L + KG K+ S
Sbjct: 743 KQVAIICNHQRSVSKSHSAQMTKLNEKIDELQDVLKELKVDLDRARKGKSPTKSSDGKSK 802
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAADL 457
+ PE+LE + A+ K D+
Sbjct: 803 -------RSLTPEVLEKKISQTNAKIEKMQRDM 828
[17][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 87.8 bits (216), Expect = 3e-16
Identities = 55/150 (36%), Positives = 81/150 (54%), Gaps = 5/150 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+LMPGL+AK FRT+NAS+TL E L + + V +K+ YN+ N
Sbjct: 673 DLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKIVIYNQAN 732
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGG---KGAKAGAA 349
K VA +CNH RT+ H M +L + E + +KELK L + KG KGA
Sbjct: 733 KQVAIICNHQRTISKSHDAQMSRLTEKIEELKSTLKELKTDLDRAKKGKPPLKGADGKQK 792
Query: 350 SS-PPVEVTQYMPVKPEILESMTADEKAQE 436
S P + + + + +E M K +E
Sbjct: 793 RSLTPEAIEKKIATTNQKIEKMEMAMKTKE 822
[18][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 87.4 bits (215), Expect = 4e-16
Identities = 55/151 (36%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ +L T LN +LK LMPGL+AK FRT+NAS+TL + L + + T+ +K+A Y + N
Sbjct: 712 DLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRAN 771
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG-----GKGAKAG 343
K VA +CNH R++ H M +L + E A ELK L+K KG K K
Sbjct: 772 KEVAIICNHQRSVSKSHDSQMTRLNEKIDELKAQRDELKADLSKVRKGKNLGNDKDGKPK 831
Query: 344 AASSPPVEVTQYMPVKPEILESMTADEKAQE 436
+P + ++ +I E M D+K +E
Sbjct: 832 RNLAPEAFEKKISQIETKI-EKMEMDKKIKE 861
[19][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 87.4 bits (215), Expect = 4e-16
Identities = 55/151 (36%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ +L T LN +LK LMPGL+AK FRT+NAS+TL + L + + T+ +K+A Y + N
Sbjct: 712 DLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRAN 771
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG-----GKGAKAG 343
K VA +CNH R++ H M +L + E A ELK L+K KG K K
Sbjct: 772 KEVAIICNHQRSVSKSHDSQMTRLNEKIDELKAQRDELKADLSKVRKGKNLGNDKDGKPK 831
Query: 344 AASSPPVEVTQYMPVKPEILESMTADEKAQE 436
+P + ++ +I E M D+K +E
Sbjct: 832 RNLAPEAFEKKISQIETKI-EKMEMDKKIKE 861
[20][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 86.3 bits (212), Expect = 1e-15
Identities = 56/158 (35%), Positives = 83/158 (52%), Gaps = 7/158 (4%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ ++ T LN +LK LMPGL+AK FRT+NAS+TL L + + T+ +K+A Y + NK
Sbjct: 718 LFDKIDTTRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTLLEKIAVYQRANK 777
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPP 361
VA +CNH R++ H+ M KL + E + ++ELK L+K AK G
Sbjct: 778 EVAIICNHQRSVSKSHESQMIKLNEKIDELKSQMEELKADLSK-------AKKGKPLGYD 830
Query: 362 VEVTQYMPVKPEILESMTA------DEKAQERKRAADL 457
E Q + PE +E A D+ ++K DL
Sbjct: 831 KEGKQKRNLAPEAIEKKIAMVEGKIDKMEMDKKIKEDL 868
[21][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 86.3 bits (212), Expect = 1e-15
Identities = 57/154 (37%), Positives = 77/154 (50%), Gaps = 3/154 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ +L + LN +LK+LMPGL+AK FRT+NAS+TL E L D E V KV Y N
Sbjct: 654 DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVVVYQHAN 713
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H M +L + E + LK LA+ KG P
Sbjct: 714 KEVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKG----------KP 763
Query: 359 PVEVT--QYMPVKPEILESMTADEKAQERKRAAD 454
P++ + + PE LE A A+ K D
Sbjct: 764 PLKDADGKRRNLTPEALERKIAQTNAKIEKMERD 797
[22][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 85.1 bits (209), Expect = 2e-15
Identities = 50/118 (42%), Positives = 71/118 (60%), Gaps = 6/118 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RLS TSLN +L +LMPGLSAK FRT+NAS+TL + L + G +VT K YN+
Sbjct: 512 DLFDRLSTTSLNKFLGELMPGLSAKVFRTYNASITLQQQLNELTEEGASVTAKFLQYNRA 571
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
N+ VA LCNH R P M +KL+ ++ + A KE+K ++++ GK K
Sbjct: 572 NRAVAILCNHQRAAPKTFDKQMENIVNKLKEKKKQMKAVKKEIKELKREYHEKGKSEK 629
[23][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 84.7 bits (208), Expect = 3e-15
Identities = 48/117 (41%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN YL++LM GL+AK FRT+NAS+TL + L PGE + +K+ YN+
Sbjct: 546 DLFDRLNTSILNKYLQELMDGLTAKVFRTYNASITLQQQLNELTSPGENIPEKILSYNRA 605
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+T+ + E K+ L+ K K AKA A
Sbjct: 606 NRAVALLCNHQRAPPKTFEKSMQNLQTK-------IDEKKKQLSAAKKEHKAAKADA 655
[24][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 84.7 bits (208), Expect = 3e-15
Identities = 53/129 (41%), Positives = 74/129 (57%), Gaps = 4/129 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQN 178
++ +L + LN +LK+LMPGL+AK FRT+NASVTL + L + G + +KVA YN N
Sbjct: 673 DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLAN 732
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGG---KGAKAGAA 349
K VA +CNH R++ H + KL + E A ++E K LA+ KG KGA A
Sbjct: 733 KEVAIICNHQRSVSKSHSVQISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAK 792
Query: 350 SSPPVEVTQ 376
+ E Q
Sbjct: 793 RNLAPEALQ 801
[25][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 84.7 bits (208), Expect = 3e-15
Identities = 46/113 (40%), Positives = 65/113 (57%), Gaps = 6/113 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ------GDPGETVTDKVAF 163
++ +L + LN +LK+LMPGL+AK FRT+NAS+TL E ++ G V +KV
Sbjct: 559 DLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMVRCKLLSRETKGGDVAEKVVV 618
Query: 164 YNKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
Y NK VA +CNH RT+ H M +L + E +KEL+ L + NKG
Sbjct: 619 YQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEELKGLLKELQEDLTRVNKG 671
[26][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 84.3 bits (207), Expect = 4e-15
Identities = 55/155 (35%), Positives = 76/155 (49%), Gaps = 4/155 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD-PGETVTDKVAFYNKQN 178
++ +L + LN +LK LMPGL+AK FRT+NAS+TL E L + G V +K+ Y N
Sbjct: 690 DLFDKLDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHAN 749
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP 358
K VA +CNH RT+ H M +L + E + L+ LA+ KG P
Sbjct: 750 KEVAIICNHQRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKG----------KP 799
Query: 359 PVEVTQYMP---VKPEILESMTADEKAQERKRAAD 454
P+E P + PE LE A+ K D
Sbjct: 800 PLEDADGKPKRNLTPEALERKIGQTNAKIEKMERD 834
[27][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 84.3 bits (207), Expect = 4e-15
Identities = 50/116 (43%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
N+ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 399 NLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 458
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 459 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 514
[28][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 84.0 bits (206), Expect = 5e-15
Identities = 45/108 (41%), Positives = 63/108 (58%), Gaps = 1/108 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+LMPGL+AK FRT+NAS+TL E L + + V +K YN+ N
Sbjct: 656 DLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKFVIYNQAN 715
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
K VA +CNH RT+ H M +L + E +KE K L + KG
Sbjct: 716 KQVAIICNHQRTISKSHDAQMSRLTEKLEELKGTLKEFKTDLDRAKKG 763
[29][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 83.2 bits (204), Expect = 8e-15
Identities = 47/118 (39%), Positives = 70/118 (59%), Gaps = 6/118 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ T LN +L +LM GL+AK FRT+NAS TL E L+ +P +TV +K+ YN+
Sbjct: 766 DLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRA 825
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
N+ VA LCNH R++P H+ M K+E +R + KE+K + G + K
Sbjct: 826 NRAVAILCNHQRSVPKSHEKSMENLKAKIEAKREQINEIKKEVKNAKRNGDSGTEAKK 883
[30][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 83.2 bits (204), Expect = 8e-15
Identities = 43/108 (39%), Positives = 67/108 (62%), Gaps = 1/108 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ ++ + LN +LK LMPGL+AK FRT+NAS+TL L + + TV +K+A Y + N
Sbjct: 370 DLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTVLEKIAVYQRAN 429
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
K VA +CNH R++ H+ M ++ + E + ++ELK L K KG
Sbjct: 430 KEVAIICNHQRSVSKSHESQMTRMNEKIDELKSQMEELKADLNKAKKG 477
[31][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 83.2 bits (204), Expect = 8e-15
Identities = 40/86 (46%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL+ + LN++L LMPGLSAK FRT NAS T++E L+ P + +++DKV YN+ N+
Sbjct: 486 LFDRLNTSKLNNHLTSLMPGLSAKVFRTHNASYTMSEQLKNTPKDASISDKVLAYNRANR 545
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
+VA LCNH RT+ H M ++E +
Sbjct: 546 MVAILCNHQRTISKTHSAQMERIEDK 571
[32][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 82.8 bits (203), Expect = 1e-14
Identities = 47/107 (43%), Positives = 67/107 (62%), Gaps = 9/107 (8%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQN 178
+ RL+ T +N +L +LM GL+AK FRT+NAS TL + L+ DP TV +K+ YN+ N
Sbjct: 819 LFDRLNTTVMNKHLNELMDGLTAKVFRTYNASWTLQQQLEELTDPNSTVAEKILSYNRAN 878
Query: 179 KVVAELCNHVRTLPSGHKGHMH----KLETRR---AEAVAWVKELKR 298
+ VA LCNH R++P H+ M K++ +R AEA VK+ KR
Sbjct: 879 RAVAILCNHQRSVPKSHEKSMENLKAKIDAKREAIAEAEQIVKDAKR 925
[33][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 82.8 bits (203), Expect = 1e-14
Identities = 44/123 (35%), Positives = 75/123 (60%), Gaps = 2/123 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + +N +L +LM GL+AK FRT+NAS TL E L + +T+++K+ YN+
Sbjct: 58 DLFDRLNTSIMNKHLNELMDGLTAKVFRTYNASSTLQEQLDLLTNEDDTLSEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R++P GH+ M KL+ + + +++E+++ + K AK G+
Sbjct: 118 NRAVAILCNHQRSVPKGHQKSMEKLKEKIEQKREFIQEMQKXV---KDAAKDAKHGSVKE 174
Query: 356 PPV 364
V
Sbjct: 175 KVV 177
[34][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 194 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 253
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 254 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 309
[35][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 82.4 bits (202), Expect = 1e-14
Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RLS TSLN YL +LM GL+AK FRT+NAS TL E L DP ++ DK+ YN+
Sbjct: 358 DLFDRLSTTSLNKYLSELMEGLTAKVFRTYNASYTLQEQLHQVIDPKMSIEDKILIYNRS 417
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH RT+ M L + + +KE K+
Sbjct: 418 NRAVAILCNHQRTVSKTFDKQMSNLREKIEKKEQQLKEAKK 458
[36][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 301 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 360
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 361 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[37][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 301 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 360
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 361 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[38][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 194 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 253
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 254 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 309
[39][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 301 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 360
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 361 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[40][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 82.4 bits (202), Expect = 1e-14
Identities = 44/88 (50%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQ 175
+I RL+ T LN +LK M GL+AK FRT+NAS T++ LQ P E T+ +KV YN
Sbjct: 609 DIFDRLTTTQLNKHLKSYMDGLTAKVFRTYNASFTMSRLLQELPVEKATIAEKVKLYNDC 668
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH RT+ +GH+ M KL R
Sbjct: 669 NRKVAILCNHKRTVGAGHQAQMEKLGDR 696
[41][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 82.4 bits (202), Expect = 1e-14
Identities = 44/86 (51%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RLS SLN YL LM GLSAK FRT+NAS T+AE L+ P T+ DK+ FYN+ N+
Sbjct: 538 IFDRLSTNSLNKYLTSLMDGLSAKVFRTYNASYTMAEELKKMPKNLTLADKILFYNRANR 597
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH R++ H M + R
Sbjct: 598 TVAILCNHQRSVTKNHDVQMERFAER 623
[42][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 82.4 bits (202), Expect = 1e-14
Identities = 49/116 (42%), Positives = 72/116 (62%), Gaps = 6/116 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L++LM GL+AK FRT+NAS+TL E L+ +++ K+ YN+
Sbjct: 399 DLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRA 458
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVK-ELKRGLAKWNKGGKG 331
N+VVA LCNH R PS + M L+T+ + E VA + EL+R A+ G G
Sbjct: 459 NRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG 514
[43][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 82.0 bits (201), Expect = 2e-14
Identities = 49/117 (41%), Positives = 70/117 (59%), Gaps = 5/117 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN++L++LM GL+AK FRTFNAS TL L+ DP TV +K+ YN+
Sbjct: 769 DLFDRLNTSVLNEHLRELMEGLTAKVFRTFNASFTLQNQLRELTDPDMTVPEKLLAYNRA 828
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAWVKELKRGLAKWNKGGKGAK 337
N+ VA LCNH R +P H+ M L+ + + EAV + + L K N K AK
Sbjct: 829 NRAVAILCNHQRAVPKTHEKSMSNLKEKIRAKQEAVETCERELKDLKKSNVRDKVAK 885
[44][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 82.0 bits (201), Expect = 2e-14
Identities = 54/154 (35%), Positives = 84/154 (54%), Gaps = 3/154 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP +V +K+ YN+
Sbjct: 842 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQNQLDLLTDPNASVAEKLLTYNRA 901
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAAS 352
N+ VA LCNH R++P GH+ M L+ + RA+ A L ++++ K AK G+
Sbjct: 902 NRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----LDECESEYHDLRKAAKRGS-- 955
Query: 353 SPPVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
+ E + AD+K ++ +R D
Sbjct: 956 ---------------VKEKLNADKKGKQLERLKD 974
[45][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 81.3 bits (199), Expect = 3e-14
Identities = 41/88 (46%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 853 DLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRA 912
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH+ M L+ +
Sbjct: 913 NRAVAILCNHQRSVPKGHQKSMENLKEK 940
[46][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 81.3 bits (199), Expect = 3e-14
Identities = 41/88 (46%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 841 DLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRA 900
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH+ M L+ +
Sbjct: 901 NRAVAILCNHQRSVPKGHQKSMENLKEK 928
[47][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 81.3 bits (199), Expect = 3e-14
Identities = 41/88 (46%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 803 DLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 862
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH+ M L+ +
Sbjct: 863 NRAVAILCNHQRSVPKGHQKSMENLKEK 890
[48][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 81.3 bits (199), Expect = 3e-14
Identities = 45/123 (36%), Positives = 72/123 (58%), Gaps = 2/123 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL E L + ++VT+K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMDGLTAKVFRTYNASSTLQEQLDLLTNEDDSVTEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R++P GH+ M KL+ + + + E+++ + K AK G+
Sbjct: 118 NRAVAILCNHQRSVPKGHQKSMEKLKEKIEQKKEHIAEMQKQV---KDAAKDAKHGSVKE 174
Query: 356 PPV 364
V
Sbjct: 175 KVV 177
[49][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 80.9 bits (198), Expect = 4e-14
Identities = 44/91 (48%), Positives = 59/91 (64%), Gaps = 5/91 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGE--TVTDKVAFY 166
++ RL+ T LN +L MPGL+AK FRT+NAS T++E L+G DP +V +KV Y
Sbjct: 633 DLFDRLTTTQLNKHLTNYMPGLTAKVFRTYNASFTMSELLKGLSKDPRSRGSVAEKVKLY 692
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N N+ VA LCNH RT+ +GH+ M KL R
Sbjct: 693 NDCNREVAILCNHKRTVGAGHEQQMQKLGDR 723
[50][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 80.5 bits (197), Expect = 5e-14
Identities = 47/120 (39%), Positives = 70/120 (58%), Gaps = 2/120 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ + LN +L +LM GL+AK FRTFNAS TL + L+ DP +V +K+ YN+
Sbjct: 546 DLFDRLNTSILNQHLHELMDGLTAKVFRTFNASWTLQQQLEKLTDPDVSVAEKILQYNRA 605
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R +P H+ M L+ + A VKE K ++ + + K G+ S
Sbjct: 606 NRAVAILCNHQRAIPKTHEKSMGNLKEKIQTKRAAVKEAKE---QYKQAKRDVKDGSVHS 662
[51][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 80.5 bits (197), Expect = 5e-14
Identities = 41/101 (40%), Positives = 66/101 (65%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL E L + ++VT+K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASHTLQEQLDKLTNAEDSVTEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH R++P GH+ M KL+ + + ++E++R
Sbjct: 118 NRAVAILCNHQRSVPKGHQKSMEKLKEKIDQKREQIEEMQR 158
[52][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 80.1 bits (196), Expect = 7e-14
Identities = 42/108 (38%), Positives = 66/108 (61%), Gaps = 1/108 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ ++ + LN +LK LMPGL+AK FRT+NAS+TL L + + TV +K+A Y + N
Sbjct: 700 DLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTVLEKIAVYQRAN 759
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
K VA +CN R++ H+ M ++ + E + ++ELK L K KG
Sbjct: 760 KEVAIICNQQRSVSKSHESQMTRMNEKIDELKSQMEELKADLNKAKKG 807
[53][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 80.1 bits (196), Expect = 7e-14
Identities = 44/105 (41%), Positives = 64/105 (60%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + +N+YLK LM GL+AK FRTFNAS TL + L+ DP +V +K+ YN+
Sbjct: 787 DLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRA 846
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P H+ M K+ +R + KE K+
Sbjct: 847 NRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKK 891
[54][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 80.1 bits (196), Expect = 7e-14
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L D TV +K+ YN+
Sbjct: 862 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDGSATVAEKLLAYNRA 921
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R++P GH+ M L+ + + + + A+++ K AK G+
Sbjct: 922 NRAVAILCNHQRSVPKGHQKSMDNLKEKIRAKRDNIDDCE---AEYHDLKKAAKRGS--- 975
Query: 356 PPVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
+ E + AD+KA++ +R D
Sbjct: 976 --------------VKEKVNADKKAKQLERLKD 994
[55][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 79.7 bits (195), Expect = 9e-14
Identities = 52/115 (45%), Positives = 64/115 (55%), Gaps = 4/115 (3%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T A L+ E TV +KV YN N+
Sbjct: 585 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANR 644
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR--RAEAVAW-VKELKRGLAKWNKGGKGAK 337
VA LCNH RT+ +GH M KL R W VK + L K KGAK
Sbjct: 645 RVAILCNHKRTVTAGHANQMEKLGDRIKGLRYQKWRVKMMMLDLDPSQKKKKGAK 699
[56][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 79.3 bits (194), Expect = 1e-13
Identities = 46/108 (42%), Positives = 64/108 (59%), Gaps = 6/108 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RLS TSLN +L+ LM GL+AK FRT+NAS+TL E L+ D + V K+ YN+
Sbjct: 487 DLFDRLSTTSLNKHLQDLMDGLTAKVFRTYNASITLQEQLKALTDAEDNVAAKILSYNRA 546
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKRGLA 307
N+ VA LCNH R P + M K++ ++ + V ELKR A
Sbjct: 547 NRAVAILCNHQRATPKTFEKSMQNLQAKIDAKKEQLDEAVTELKRAKA 594
[57][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 79.3 bits (194), Expect = 1e-13
Identities = 40/101 (39%), Positives = 64/101 (63%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 92 DLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNDDDTVAEKILSYNRA 151
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH R++P GH+ M KL+ + + + E++R
Sbjct: 152 NRAVAILCNHQRSVPKGHQKTMEKLKEKIEQKREQINEMQR 192
[58][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 79.3 bits (194), Expect = 1e-13
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 9/109 (8%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ + LN++L+ LM GL+AK FRTFNAS TL L DP TV +K+ YN+
Sbjct: 764 DLFDRLNTSVLNEHLRDLMDGLTAKVFRTFNASFTLQNQLAELTDPNMTVPEKMLAYNRA 823
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR---RAEAVAW----VKELKRG 301
N+ VA LCNH R +P H M L+ + + EAV +K++KRG
Sbjct: 824 NRAVAILCNHQRAVPKTHDKSMSNLKEKIRLKKEAVETCQRELKDMKRG 872
[59][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 79.3 bits (194), Expect = 1e-13
Identities = 46/107 (42%), Positives = 63/107 (58%), Gaps = 2/107 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN +L+ MPGL+AK FRT+NAS T+ + L P E TV +K+ YN N+
Sbjct: 507 LFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKILRYNAANR 566
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGLAKWNK 319
VA LCNH RT+ GH + K T R E + W K KR + + +K
Sbjct: 567 TVAILCNHQRTVTKGHASSVQK-ATERIEELEWQKVRYKRAILQLDK 612
[60][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 394 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 453
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 454 NRAVAILCNHQRSVPKSHEKSMENLKEK 481
[61][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/102 (41%), Positives = 60/102 (58%), Gaps = 3/102 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP---GETVTDKVAFYNK 172
+I ++ T LND+LK M GLSAK FRT+NAS+TL + P +V DK+A++NK
Sbjct: 386 DIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLAYFNK 445
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N VA LCNH +++ H MH+L + + + LKR
Sbjct: 446 ANTEVAILCNHQKSISKNHHNLMHQLTQKSSYTRTIIDALKR 487
[62][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/102 (41%), Positives = 60/102 (58%), Gaps = 3/102 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP---GETVTDKVAFYNK 172
+I ++ T LND+LK M GLSAK FRT+NAS+TL + P +V DK+A++NK
Sbjct: 386 DIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLAYFNK 445
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N VA LCNH +++ H MH+L + + + LKR
Sbjct: 446 ANTEVAILCNHQKSISKNHHNLMHQLTQKSSYTRTIIDALKR 487
[63][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 787 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 846
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 847 NRAVAILCNHQRSVPKSHEKSMENLKEK 874
[64][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 393 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 452
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 453 NRAVAILCNHQRSVPKSHEKSMENLKEK 480
[65][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 783 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 842
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 843 NRAVAILCNHQRSVPKSHEKSMENLKEK 870
[66][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 782 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 841
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 842 NRAVAILCNHQRSVPKSHEKSMENLKEK 869
[67][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 79.0 bits (193), Expect = 2e-13
Identities = 41/111 (36%), Positives = 66/111 (59%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 92 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 151
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
N+ VA LCNH R++P GH M KL+ + + + E++R + + K
Sbjct: 152 NRAVAILCNHQRSVPKGHAKSMEKLKEKIEQKKDTISEMERQVQDAQRAAK 202
[68][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/104 (40%), Positives = 67/104 (64%), Gaps = 6/104 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ + LN +L +LM GL+AK FRT+NAS TL + L + ++V++K+ YN+
Sbjct: 40 DLFDRLNTSILNKHLNELMEGLTAKVFRTYNASFTLQQQLDQLTNADDSVSEKMLSYNRA 99
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLE----TRRAEAVAWVKELK 295
N+ VA LCNH R++P GH+ M KL+ T+R + K++K
Sbjct: 100 NRAVAVLCNHQRSVPKGHEKSMEKLKEKIGTKRDQIAEMEKQVK 143
[69][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 79.0 bits (193), Expect = 2e-13
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN +L+ MPGL+AK FRT+NAS T+ + L P E TV +K+ YN N+
Sbjct: 478 LFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKMLKYNAANR 537
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGL 304
VA LCNH RT+ GH + K T R E + W K LKR +
Sbjct: 538 TVAILCNHQRTVTKGHAASVQK-ATERIEELEWQKIRLKRAI 578
[70][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 79.0 bits (193), Expect = 2e-13
Identities = 43/86 (50%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T A L+ E TV +KV YN N+
Sbjct: 581 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANR 640
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ +GH M KL R
Sbjct: 641 RVAILCNHKRTVTAGHANQMEKLGDR 666
[71][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 79.0 bits (193), Expect = 2e-13
Identities = 40/88 (45%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 785 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 844
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 845 NRAVAILCNHQRSVPKSHEKSMENLKEK 872
[72][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 79.0 bits (193), Expect = 2e-13
Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 2/114 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQ 175
++ RL +LND+L+ LM GL+ K FRT+NAS+TL E L +P + V K+ YN+
Sbjct: 540 DLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRA 599
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
N+ VA LCNH R + G M KLE + + VKE + L K +GA+
Sbjct: 600 NRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAAL----KSARGAE 649
[73][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 79.0 bits (193), Expect = 2e-13
Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 2/114 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQ 175
++ RL +LND+L+ LM GL+ K FRT+NAS+TL E L +P + V K+ YN+
Sbjct: 612 DLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRA 671
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
N+ VA LCNH R + G M KLE + + VKE + L K +GA+
Sbjct: 672 NRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAAL----KSARGAE 721
[74][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 78.6 bits (192), Expect = 2e-13
Identities = 40/88 (45%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 394 DLFDRLKTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 453
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H+ M L+ +
Sbjct: 454 NRAVAILCNHQRSVPKSHEKSMENLKEK 481
[75][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 78.6 bits (192), Expect = 2e-13
Identities = 40/88 (45%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL + L D TV +K+ YN+
Sbjct: 796 DLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQDQLDKLTDGDATVAEKLLAYNRA 855
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH+ M L+ +
Sbjct: 856 NRAVAILCNHQRSVPKGHQKSMENLKEK 883
[76][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 78.6 bits (192), Expect = 2e-13
Identities = 42/111 (37%), Positives = 66/111 (59%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ + +N +L +LM GL+AK FRT+NAS TL + L +TV +K+ YN+
Sbjct: 58 DLFDRLNTSIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTSADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
N+ VA LCNH R++P GH+ M KL+ + + V + +R L + K
Sbjct: 118 NRAVAILCNHQRSVPKGHQKSMEKLKEKIEQKREQVADAQRQLKDAQRDAK 168
[77][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 78.6 bits (192), Expect = 2e-13
Identities = 43/105 (40%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL SLN YL+ LMPGL+AK FRT+NAS+TL + L T + + YN+
Sbjct: 559 DLFDRLDTASLNKYLQSLMPGLTAKVFRTYNASITLQQQLDKLTKDDSTAPELLLCYNRA 618
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAK 310
N+ VA LCNH R +P H+ M L+ + +KE K L K
Sbjct: 619 NRQVAILCNHQRAVPKSHEKSMENLKAKIKAKKTELKEAKEELEK 663
[78][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 78.6 bits (192), Expect = 2e-13
Identities = 44/103 (42%), Positives = 64/103 (62%), Gaps = 2/103 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ RL + LN YL+ MPGL+AK FRT+NAS T+ + L P E TV +K+ YN N
Sbjct: 465 DLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKLLKYNAAN 524
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGL 304
+ VA LCNH R++ GH + K+ ++ E + W K LK+G+
Sbjct: 525 RAVAILCNHQRSVTKGHAQSVEKM-NQKIEELLWQKIRLKKGI 566
[79][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 78.2 bits (191), Expect = 3e-13
Identities = 44/103 (42%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQ 175
N+ RL+ + LN YL++LM GL+AK FRT+NAS TL L D ++VT K+ YN+
Sbjct: 238 NLFDRLNTSILNKYLQELMEGLTAKVFRTYNASSTLQNQLVELTDADDSVTAKMLSYNRA 297
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGL 304
N+ VA LCNH R P M L+ + + +KE K+GL
Sbjct: 298 NRAVAVLCNHQRAAPKTFDKQMENLQEKIDKKHLDIKEAKKGL 340
[80][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E471B7
Length = 879
Score = 78.2 bits (191), Expect = 3e-13
Identities = 44/103 (42%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQ 175
N+ RL+ + LN YL++LM GL+AK FRT+NAS TL L D ++VT K+ YN+
Sbjct: 677 NLFDRLNTSILNKYLQELMEGLTAKVFRTYNASSTLQNQLVELTDADDSVTAKMLSYNRA 736
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGL 304
N+ VA LCNH R P M L+ + + +KE K+GL
Sbjct: 737 NRAVAVLCNHQRAAPKTFDKQMENLQEKIDKKHLDIKEAKKGL 779
[81][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 78.2 bits (191), Expect = 3e-13
Identities = 39/101 (38%), Positives = 65/101 (64%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRTFNAS TL + L + +T+++K+ YN+
Sbjct: 92 DLFDRLNTQIMNKHLNELMDGLTAKVFRTFNASYTLQQQLDELTNADDTLSEKILSYNRA 151
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH R++P GH+ M KL+ + + + E+++
Sbjct: 152 NRAVAILCNHQRSVPKGHQKTMEKLKEKIDQKREQITEMQK 192
[82][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 78.2 bits (191), Expect = 3e-13
Identities = 43/103 (41%), Positives = 61/103 (59%), Gaps = 5/103 (4%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNK 181
+ RL LN+YL+ LM GL+AK FRT+NAS+TL + L+ P G TV +K+ Y + N+
Sbjct: 2211 LFDRLRTQQLNEYLQSLMDGLTAKVFRTYNASITLQDQLKSTPAGGTVEEKLLAYQRANR 2270
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR----RAEAVAWVKELKR 298
VA LCNH R P H M +L+ + E + +KE K+
Sbjct: 2271 AVAILCNHQRAAPKTHDEQMERLDEALVKIQKELDSTIKERKK 2313
[83][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 77.8 bits (190), Expect = 4e-13
Identities = 44/123 (35%), Positives = 70/123 (56%), Gaps = 2/123 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + ++V +K+ YN+
Sbjct: 735 DLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNADDSVAEKILAYNRA 794
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R++P GH+ M KL+ + +K+ +R + K AK G+
Sbjct: 795 NRAVAILCNHQRSVPKGHEKSMEKLKEKIDAKKEAIKDAERQV---KDAAKDAKHGSVKE 851
Query: 356 PPV 364
V
Sbjct: 852 KTV 854
[84][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 77.8 bits (190), Expect = 4e-13
Identities = 53/158 (33%), Positives = 78/158 (49%), Gaps = 6/158 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+LM GL+AK FRT+NAS+TL L + + V +KV Y + N
Sbjct: 707 DLFDELDTSKLNTHLKELMAGLTAKVFRTYNASITLDLMLSKETRDGDVPEKVVVYQQAN 766
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG-----GKGAKAG 343
K VA +CNH RT+ H + KL + E +KEL L + KG G K
Sbjct: 767 KEVAIICNHQRTVSKSHGAQVEKLAVKIEELREQIKELNIDLDRAKKGRTPLMGSDGKRK 826
Query: 344 AASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 457
+P + M + +I E M D + +E + L
Sbjct: 827 RNLTPEALEKKIMQTQGKI-EKMERDMQTKEDMKTVAL 863
[85][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 77.8 bits (190), Expect = 4e-13
Identities = 53/158 (33%), Positives = 78/158 (49%), Gaps = 6/158 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+LM GL+AK FRT+NAS+TL L + + V +KV Y + N
Sbjct: 22 DLFDELDTSKLNTHLKELMAGLTAKVFRTYNASITLDLMLSKETRDGDVPEKVVVYQQAN 81
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG-----GKGAKAG 343
K VA +CNH RT+ H + KL + E +KEL L + KG G K
Sbjct: 82 KEVAIICNHQRTVSKSHGAQVEKLAVKIEELREQIKELNIDLDRAKKGRTPLMGSDGKRK 141
Query: 344 AASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 457
+P + M + +I E M D + +E + L
Sbjct: 142 RNLTPEALEKKIMQTQGKI-EKMERDMQTKEDMKTVAL 178
[86][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 77.8 bits (190), Expect = 4e-13
Identities = 58/158 (36%), Positives = 82/158 (51%), Gaps = 7/158 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE----TVTDKVAFYN 169
++ +L+ +SLN YLK M LSAK FRT+NAS+TL + L P T +KV FYN
Sbjct: 757 DLFDQLTTSSLNKYLKGFMENLSAKVFRTYNASLTLEKELAKMPESLIKATADEKVLFYN 816
Query: 170 KQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAA 349
+ N+ VA LCNH R+L H M K++ + AE + KE + + K GKG K +
Sbjct: 817 RCNREVAILCNHQRSLSKTHTETMGKIDEKIAE---FKKEKLQQQIAYLK-GKGKKPVLS 872
Query: 350 SSPPVEVTQYMPVKPEIL---ESMTADEKAQERKRAAD 454
S E T + E+ ++DE +KR D
Sbjct: 873 DSESDEDTPKKATPKKATPKKETKSSDEATPNKKRKKD 910
[87][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 77.0 bits (188), Expect = 6e-13
Identities = 39/88 (44%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L D +V +K+ YN+
Sbjct: 844 DLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDSNASVAEKLLTYNRA 903
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH+ M L+ +
Sbjct: 904 NRAVAILCNHQRSVPKGHQKSMENLKEK 931
[88][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 77.0 bits (188), Expect = 6e-13
Identities = 40/111 (36%), Positives = 67/111 (60%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +T+ +K+ YN+
Sbjct: 92 DLFDRLNTQIMNKHLNELMDGLTAKVFRTYNASWTLQQQLDELTNADDTLAEKILSYNRA 151
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
N+ VA LCNH R++P GH+ M KL+ + + + +++R + K K
Sbjct: 152 NRAVAILCNHQRSVPKGHQKSMEKLKEKIDQKKENITDMQRQVKDAQKDAK 202
[89][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 77.0 bits (188), Expect = 6e-13
Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+G T+ +K+ YN N+
Sbjct: 621 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANR 680
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 681 QVAILCNHKRTVTASHSTQMEKLGDR 706
[90][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 77.0 bits (188), Expect = 6e-13
Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+G T+ +K+ YN N+
Sbjct: 626 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANR 685
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 686 QVAILCNHKRTVTASHSTQMEKLGDR 711
[91][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans
RepID=Q5KB99_CRYNE
Length = 881
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 603 DIFDRLTTTLLNKHLNSMMPGLTAKVFRTYNASWTFQEQLKNTPKNGTVAEKIAAYNTAN 662
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 663 RDVAILCNHQKSVSKGFEGSFAKAEDK 689
[92][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 75.9 bits (185), Expect = 1e-12
Identities = 39/88 (44%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RLS LN +L++LM GL+AK FRT+NAS+TL E L+ +P ++V K+ YN+
Sbjct: 391 DLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNASITLQEQLKALTNPEDSVAGKLLSYNRA 450
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R+ P + M L+T+
Sbjct: 451 NRAVAILCNHQRSTPKTFEKSMQNLQTK 478
[93][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 75.9 bits (185), Expect = 1e-12
Identities = 39/88 (44%), Positives = 58/88 (65%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RLS LN +L++LM GL+AK FRT+NAS+TL E L+ +P ++V K+ YN+
Sbjct: 391 DLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNASITLQEQLKALTNPEDSVAGKLLSYNRA 450
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R+ P + M L+T+
Sbjct: 451 NRAVAILCNHQRSTPKTFEKSMQNLQTK 478
[94][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 75.5 bits (184), Expect = 2e-12
Identities = 45/111 (40%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ TSLN +L+ LM GL+AK FRT+NASVTL E L+ ++V K+ YN+
Sbjct: 453 DLFDRLTTTSLNKHLQDLMDGLTAKVFRTYNASVTLQEQLRALTRAEDSVAAKILSYNRA 512
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
N+ VA LCNH R P + M L+ + V E K L + G K
Sbjct: 513 NRAVAILCNHQRATPKTFEKSMQNLQLKIEAKKKQVAEAKAELKQARAGHK 563
[95][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 75.5 bits (184), Expect = 2e-12
Identities = 38/101 (37%), Positives = 63/101 (62%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ LN +L +LM GL+AK FRT+NAS TL + L + +++++K+ YN+
Sbjct: 58 DLFDRLNTAILNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNEDDSISEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P GH+ M K++ + +K+ +R
Sbjct: 118 NRAVAILCNHQRAVPKGHEKSMEKIKEKIDAKRQAIKDAER 158
[96][TOP]
>UniRef100_Q8WZF2 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZF2_CRYNE
Length = 270
Score = 75.5 bits (184), Expect = 2e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 36 DIFDRLTTTLLNKHLNGMMPGLTAKVFRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTAN 95
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 96 RDVAILCNHQKSVSKGFEGSFAKAEDK 122
[97][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 75.5 bits (184), Expect = 2e-12
Identities = 41/85 (48%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
+I RL+ T LN +L MPGL+AK FRT+NAS T+++ LQ TV +KV YN
Sbjct: 591 DIFDRLTTTQLNKHLSSYMPGLTAKVFRTYNASYTMSKLLQELKVTNATVHEKVKLYNDC 650
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKL 250
N+ VA LCNH RT+ + H+ M KL
Sbjct: 651 NRQVAILCNHKRTVGASHEQQMKKL 675
[98][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 75.5 bits (184), Expect = 2e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 566 DIFDRLTTTLLNKHLNGMMPGLTAKVFRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTAN 625
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 626 RDVAILCNHQKSVSKGFEGSFAKAEDK 652
[99][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 75.5 bits (184), Expect = 2e-12
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN YL+ MPGL+AK FRT+NAS T+ + L P + +V +K+ YN N+
Sbjct: 467 LFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANR 526
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSP 358
VA LCNH RT+ GH + K R E + W K KR + + +K
Sbjct: 527 TVAILCNHQRTVTKGHAQTVEKANNRIQE-LEWQKIRCKRAILQLDK------------- 572
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
++ + P E ++ +T +++A KR D
Sbjct: 573 --DLLKKEPKYFEEIDDLTKEDEATIHKRIID 602
[100][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 75.5 bits (184), Expect = 2e-12
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN YL+ MPGL+AK FRT+NAS T+ + L P + +V +K+ YN N+
Sbjct: 491 LFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANR 550
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSP 358
VA LCNH RT+ GH + K R E + W K KR + + +K
Sbjct: 551 TVAILCNHQRTVTKGHAQTVEKANNRIQE-LEWQKIRCKRAILQLDK------------- 596
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
++ + P E ++ +T +++A KR D
Sbjct: 597 --DLLKKEPKYFEEIDDLTKEDEATIHKRIID 626
[101][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 75.5 bits (184), Expect = 2e-12
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN YL+ MPGL+AK FRT+NAS T+ + L P + +V +K+ YN N+
Sbjct: 491 LFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANR 550
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSP 358
VA LCNH RT+ GH + K R E + W K KR + + +K
Sbjct: 551 TVAILCNHQRTVTKGHAQTVEKANNRIQE-LEWQKIRCKRAILQLDK------------- 596
Query: 359 PVEVTQYMPVKPEILESMTADEKAQERKRAAD 454
++ + P E ++ +T +++A KR D
Sbjct: 597 --DLLKKEPKYFEEIDDLTKEDEATIHKRIID 626
[102][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 75.1 bits (183), Expect = 2e-12
Identities = 43/104 (41%), Positives = 62/104 (59%), Gaps = 6/104 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RLS LN +L+ LM GL+AK FRT+NAS+TL + LQ DP E++ K+ YN+
Sbjct: 301 DLFDRLSTPLLNKHLQSLMEGLTAKVFRTYNASITLQQQLQELTDPEESMPSKILSYNRA 360
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELK 295
N+ VA LCNH R P M K++ ++ + + KELK
Sbjct: 361 NRAVAILCNHQRAPPKTFDQSMANLKSKIDAKKEQILLAKKELK 404
[103][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 75.1 bits (183), Expect = 2e-12
Identities = 42/104 (40%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKL----ETRRAEAVAWVKELK 295
N+ VA LCNH R++P H M KL E +R + V K++K
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEKIEQKREQIVDAQKQVK 161
[104][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 75.1 bits (183), Expect = 2e-12
Identities = 42/104 (40%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKL----ETRRAEAVAWVKELK 295
N+ VA LCNH R++P H M KL E +R + V K++K
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEKIEQKREQIVDAQKQVK 161
[105][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 75.1 bits (183), Expect = 2e-12
Identities = 56/182 (30%), Positives = 78/182 (42%), Gaps = 33/182 (18%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-------------DPGET 142
+I +++ LNDYLK LM GL+AK FRT+NAS+TL L+ PG++
Sbjct: 459 DIFDKINTVKLNDYLKDLMTGLTAKVFRTYNASITLCRQLRRLKVRKSLDSSLMLQPGKS 518
Query: 143 --------------VTDKVAFYNKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAW 280
V + ++FYN+ N+ VA LCNH R++P H+ M K++
Sbjct: 519 DDDLDKPVLVDVTDVNELISFYNEANRRVAILCNHQRSIPKQHESSMSKMQ--------- 569
Query: 281 VKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYM------PVKPEILESMTADEKAQERK 442
A+A S E+ YM KP ES T D K RK
Sbjct: 570 -----------------AQAELISEEIAELQAYMKYLESNQTKPFTFESRTVDAKGNPRK 612
Query: 443 RA 448
A
Sbjct: 613 AA 614
[106][TOP]
>UniRef100_Q8X232 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8X232_CRYNE
Length = 270
Score = 75.1 bits (183), Expect = 2e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 36 DIFDRLTTTLLNKHLNTMMPGLTAKVFRTYNASWTFQEQLKKTPKNGTVAEKIAAYNTAN 95
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 96 RDVAILCNHQKSVSKGFEGSFAKAEDK 122
[107][TOP]
>UniRef100_Q8WZG9 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZG9_CRYNE
Length = 270
Score = 75.1 bits (183), Expect = 2e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 36 DIFDRLTTTLLNKHLNTMMPGLTAKVFRTYNASWTFQEQLKKTPKNGTVAEKIAAYNTAN 95
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 96 RDVAILCNHQKSVSKGFEGSFAKAEDK 122
[108][TOP]
>UniRef100_Q8WZG1 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZG1_CRYNE
Length = 270
Score = 75.1 bits (183), Expect = 2e-12
Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I RL+ T LN +L +MPGL+AK FRT+NAS T E L+ P TV +K+A YN N
Sbjct: 36 DIFDRLTTTLLNKHLNTMMPGLTAKVFRTYNASWTFQEQLRKTPKNGTVAEKIAAYNTAN 95
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH +++ G +G K E +
Sbjct: 96 RDVAILCNHQKSVSKGFEGSFAKAEDK 122
[109][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 75.1 bits (183), Expect = 2e-12
Identities = 45/102 (44%), Positives = 62/102 (60%), Gaps = 2/102 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN +L+ M GL+AK FRT+NAS T+ E L P E +V +K+ YN N+
Sbjct: 439 LFDRLDPSLLNKFLQNYMTGLTAKVFRTYNASKTMQEQLDLIPNEGSVAEKLLKYNAANR 498
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKE-LKRGL 304
VA LCNH RT+ +GH + K + R E W KE LK+G+
Sbjct: 499 TVAILCNHQRTVTAGHAKSVAK-SSDRIEEFKWQKERLKKGI 539
[110][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6H1W4_PENCW
Length = 864
Score = 75.1 bits (183), Expect = 2e-12
Identities = 40/87 (45%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQN 178
I RL+ ++LN +L MPGL+AK FRT+NAS T+ L G T+ +KV YN N
Sbjct: 584 IFDRLTTSALNKHLANYMPGLTAKVFRTYNASYTMGCVLNEMNASGGTIAEKVKAYNDAN 643
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH RT+ +GH M K+ R
Sbjct: 644 RKVAILCNHKRTVTAGHANAMEKMGER 670
[111][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina
RepID=B2AY06_PODAN
Length = 904
Score = 75.1 bits (183), Expect = 2e-12
Identities = 39/88 (44%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQ 175
+I RL+ + LN +L MPGL+AK FRT+NAS T++ LQ E T+ +K+ YN
Sbjct: 621 DIFDRLTTSQLNKHLSNYMPGLTAKVFRTYNASHTMSTLLQSLSVENRTMAEKIKLYNDC 680
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA +CNH RT+ + H+ M KL R
Sbjct: 681 NREVAVICNHKRTVGAAHEAQMEKLADR 708
[112][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 74.7 bits (182), Expect = 3e-12
Identities = 52/142 (36%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDP-GETVTDKVAFYNK 172
++ RL+ ++LN YL LM GL+AK FRT+NAS+TL L DP E V K+ YN+
Sbjct: 279 DLFDRLNTSTLNKYLNSLMDGLTAKVFRTYNASITLLNQLLELTDPDDENVASKILSYNR 338
Query: 173 QNKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKRGLA--KWNKGGKGA 334
N+ VA LCNH R P M K+E ++ + +E K + K NK
Sbjct: 339 ANRAVAVLCNHQRAAPKNFSEQMGRMNEKIEKKQRDIQDAKQETKSAKSDYKHNKSEAKR 398
Query: 335 KAGAASSPPVEVTQYMPVKPEI 400
KA VE Q +K E+
Sbjct: 399 KAYEGKKKKVERLQEQLIKLEV 420
[113][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 74.7 bits (182), Expect = 3e-12
Identities = 49/135 (36%), Positives = 72/135 (53%), Gaps = 6/135 (4%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQN 178
+ RL+ + LN +L LMPGL+AK FRT+NAS+TL + L+ + ++V +K+ YN+ N
Sbjct: 419 LFDRLNTSLLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELTNESDSVAEKLLSYNRAN 478
Query: 179 KVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
+ VA LCNH R P M K+E R+ + V ELK+ K K +
Sbjct: 479 RAVAILCNHQRAPPKTFDQSMANLQSKIEARKEQLVLAKSELKQA----KKEAKAKGSAD 534
Query: 347 ASSPPVEVTQYMPVK 391
A + V + M VK
Sbjct: 535 AKLQALVVRKKMAVK 549
[114][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 74.7 bits (182), Expect = 3e-12
Identities = 44/105 (41%), Positives = 65/105 (61%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ L+ +SLN +L+ LM GL+AK FRT+NASVTL E L+ ++VT KV YN+
Sbjct: 94 DLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRA 153
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P + M K+ET++A+ EL++
Sbjct: 154 NRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVELQK 198
[115][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 74.7 bits (182), Expect = 3e-12
Identities = 44/105 (41%), Positives = 65/105 (61%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ L+ +SLN +L+ LM GL+AK FRT+NASVTL E L+ ++VT KV YN+
Sbjct: 391 DLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRA 450
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P + M K+ET++A+ EL++
Sbjct: 451 NRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVELQK 495
[116][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/89 (44%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNK 172
+I +L+ T LND+LK M GLSAK FRT+NAS+TL + DP + DK+A++NK
Sbjct: 383 DIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNK 442
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N VA LCNH +++ K M +L T+
Sbjct: 443 ANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[117][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/89 (44%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNK 172
+I +L+ T LND+LK M GLSAK FRT+NAS+TL + DP + DK+A++NK
Sbjct: 697 DIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNK 756
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N VA LCNH +++ K M +L T+
Sbjct: 757 ANTEVAILCNHQKSVSKNFKLQMMQLTTK 785
[118][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/89 (44%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNK 172
+I +L+ T LND+LK M GLSAK FRT+NAS+TL + DP + DK+A++NK
Sbjct: 383 DIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNK 442
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N VA LCNH +++ K M +L T+
Sbjct: 443 ANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[119][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/89 (44%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNK 172
+I +L+ T LND+LK M GLSAK FRT+NAS+TL + DP + DK+A++NK
Sbjct: 383 DIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNK 442
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N VA LCNH +++ K M +L T+
Sbjct: 443 ANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[120][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 74.7 bits (182), Expect = 3e-12
Identities = 39/83 (46%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +2
Query: 17 LSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVA 190
L+ LND+LK LM GL+ K FRT+NAS+TL L D TV +K+ YN+ N+ VA
Sbjct: 430 LNAHELNDHLKNLMIGLTTKVFRTYNASLTLQNQLDELTDEEATVAEKLLVYNRANRAVA 489
Query: 191 ELCNHVRTLPSGHKGHMHKLETR 259
LCNH R++P GH+ M L +
Sbjct: 490 ILCNHQRSIPKGHQQIMENLRKK 512
[121][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/88 (45%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQ 175
+I RL+ + LN +L M GL+AK FRT+NAS T+++ LQ E T+ +K+ YN
Sbjct: 624 DIFDRLTTSQLNKHLSSYMTGLTAKVFRTYNASWTMSQLLQKLEVEDRTMAEKIKLYNDC 683
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH RT+ +GH+ M KL R
Sbjct: 684 NREVAILCNHKRTVGAGHEAQMEKLGDR 711
[122][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 74.7 bits (182), Expect = 3e-12
Identities = 44/105 (41%), Positives = 65/105 (61%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ L+ +SLN +L+ LM GL+AK FRT+NASVTL E L+ ++VT KV YN+
Sbjct: 392 DLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRA 451
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P + M K+ET++A+ EL++
Sbjct: 452 NRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVELQK 496
[123][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 74.3 bits (181), Expect = 4e-12
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ LS T LN +L++LM GL+AK FRT+NAS+TL E L+ +P + + K+ YN+
Sbjct: 460 DLFDHLSTTFLNKHLQRLMDGLTAKVFRTYNASITLQEQLKALTNPEDNIAGKLLSYNRA 519
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKRGLAKWNKGGKGAKA 340
N+ VA LCNH R++P M K++ ++ + +E+K+ ++ K K AKA
Sbjct: 520 NRAVAILCNHQRSIPKTFAKSMQVLQEKIDAKKKQVEEAQEEVKKAEDEF-KDTKDAKA 577
[124][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 74.3 bits (181), Expect = 4e-12
Identities = 42/113 (37%), Positives = 63/113 (55%), Gaps = 2/113 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ SLN +L LMPGL+AK FRT+NAS+TL + L+ + + V +K+ YN+
Sbjct: 329 DLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRA 388
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGA 334
N+ VA LCNH R P M L+ + + K+ L + K KG+
Sbjct: 389 NRAVAVLCNHQRAPPKSFDQSMANLQAKIDSRKEQLDLAKKELKQAKKEAKGS 441
[125][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 74.3 bits (181), Expect = 4e-12
Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 2/139 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 714 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 773
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + K LA + K AKA A
Sbjct: 774 NRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKDQLADARRDLKSAKAEAKVR 826
Query: 356 PPVEVTQYMPVKPEILESM 412
V+ + + K + ++ +
Sbjct: 827 KDVKTKKVVETKKKAVQRL 845
[126][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 74.3 bits (181), Expect = 4e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ T +N +L +LM GL+AK FRT+NAS TL + L +P +T +K+ YN+
Sbjct: 788 DLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRA 847
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M L+ +
Sbjct: 848 NRAVAILCNHQRSVPKTHAKSMENLKAK 875
[127][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 74.3 bits (181), Expect = 4e-12
Identities = 42/113 (37%), Positives = 63/113 (55%), Gaps = 2/113 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ SLN +L LMPGL+AK FRT+NAS+TL + L+ + + V +K+ YN+
Sbjct: 407 DLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRA 466
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGA 334
N+ VA LCNH R P M L+ + + K+ L + K KG+
Sbjct: 467 NRAVAVLCNHQRAPPKSFDQSMANLQAKIDSRKEQLDLAKKELKQAKKEAKGS 519
[128][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 74.3 bits (181), Expect = 4e-12
Identities = 40/103 (38%), Positives = 62/103 (60%), Gaps = 2/103 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L +LM GL+AK FRT+NAS TL E L+ + ++ +K+ YN+
Sbjct: 80 DLFDRLNTSILNKHLNELMEGLTAKVFRTYNASKTLQEQLELLTEADMSLPEKMLAYNRA 139
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGL 304
N+ VA LCNH R +P M L+ + E A ++E K+ L
Sbjct: 140 NRAVAILCNHQRAVPKTFDKQMENLQKKMEEKEAQIRECKKEL 182
[129][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 74.3 bits (181), Expect = 4e-12
Identities = 38/101 (37%), Positives = 62/101 (61%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N+ VA LCNH R++P H M KL+ + + ++E ++
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEKIEQKREQIEEAQK 158
[130][TOP]
>UniRef100_A4HB62 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania braziliensis
RepID=A4HB62_LEIBR
Length = 637
Score = 74.3 bits (181), Expect = 4e-12
Identities = 39/89 (43%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE---TVTDKVAFYNK 172
+I +L+ T LND+LK M GLSAK FRT+NAS+TL + P + ++ DK+A++NK
Sbjct: 383 DIFDQLNPTQLNDHLKSFMNGLSAKVFRTYNASITLDRWFKEKPVDSKWSIADKLAYFNK 442
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N VA LCNH + + K M +L T+
Sbjct: 443 ANTEVAILCNHQKAISKNFKLQMMQLTTK 471
[131][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 74.3 bits (181), Expect = 4e-12
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+AE L+ + +KV YN N+
Sbjct: 593 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASHTMAELLKDMKATGNIAEKVKAYNDANR 652
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 653 RVAILCNHKRTVGASHANQMEKMSER 678
[132][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 74.3 bits (181), Expect = 4e-12
Identities = 40/86 (46%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ T+ +KV YN N+
Sbjct: 617 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKKMSATGTIPEKVKQYNDANR 676
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 677 EVAILCNHKRTVAASHANQMEKLGDR 702
[133][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 73.9 bits (180), Expect = 5e-12
Identities = 42/104 (40%), Positives = 62/104 (59%), Gaps = 6/104 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + LQ DP E++ K+ YN+
Sbjct: 301 DLFDRLNTPLLNKHLQSLMEGLTAKVFRTYNASITLQQQLQELTDPEESIPAKILSYNRA 360
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELK 295
N+ VA LCNH R P M K++ ++ + + KELK
Sbjct: 361 NRAVAILCNHQRAPPKTFDQSMANLKSKIDAKKEQILLAKKELK 404
[134][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 73.9 bits (180), Expect = 5e-12
Identities = 42/95 (44%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN +L+ MPGL+AK FRT+NAS T+ + L P E +VT+K+ YN N+
Sbjct: 454 LFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGSVTEKMVRYNAANR 513
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
VA LCNH RT+ H M K T + E W K
Sbjct: 514 AVAILCNHQRTVGRSHAQSMQK-ATEKIEEYQWQK 547
[135][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 73.9 bits (180), Expect = 5e-12
Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T+A L Q + T+ +KV YN N+
Sbjct: 626 IFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMATLLRQMNATGTIHEKVKQYNDANR 685
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ +GH M KL R
Sbjct: 686 KVAILCNHKRTVAAGHANQMEKLGER 711
[136][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 73.9 bits (180), Expect = 5e-12
Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T+A L Q + T+ +KV YN N+
Sbjct: 626 IFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMATLLRQMNATGTIHEKVKQYNDANR 685
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ +GH M KL R
Sbjct: 686 KVAILCNHKRTVAAGHANQMEKLGER 711
[137][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 73.9 bits (180), Expect = 5e-12
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ +V +KV YN N+
Sbjct: 719 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKDMKATGSVAEKVKAYNDANR 778
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 779 RVAILCNHKRTVTASHANQMEKMSER 804
[138][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 73.9 bits (180), Expect = 5e-12
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ +V +KV YN N+
Sbjct: 607 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKDMKATGSVAEKVKAYNDANR 666
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 667 RVAILCNHKRTVTASHANQMEKMSER 692
[139][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 73.6 bits (179), Expect = 7e-12
Identities = 54/154 (35%), Positives = 80/154 (51%), Gaps = 7/154 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L+ LM GL+AK FRT+NASVTL + L+ P E + K+ YN+
Sbjct: 579 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASVTLQQQLKELTAPDENIPAKILSYNRA 638
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA--- 346
N+ VA LCNH R P + M L+T+ + K LA + K AKA A
Sbjct: 639 NRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKDQLANARRDLKSAKADAKVQ 691
Query: 347 --ASSPPVEVTQYMPVKPEILESMTADEKAQERK 442
A S V T+ V+ + M + +A +R+
Sbjct: 692 RDAKSKKVVETKKKAVQRLEEQLMKLEVQATDRE 725
[140][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 73.6 bits (179), Expect = 7e-12
Identities = 50/141 (35%), Positives = 76/141 (53%), Gaps = 8/141 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL L+ E + K+ YN+
Sbjct: 553 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQAQLKELTSAEENIPAKILSYNRA 612
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLET----RRAEAVAWVKELK--RGLAKWNKGGKGAK 337
N+ VA LCNH R P + M L+T ++A+ A +ELK + AK + K K
Sbjct: 613 NRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKK 672
Query: 338 AGAASSPPVEVTQYMPVKPEI 400
A A V+ +K E+
Sbjct: 673 AVEAKKKAVQRIDDQLMKLEV 693
[141][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 73.6 bits (179), Expect = 7e-12
Identities = 50/141 (35%), Positives = 76/141 (53%), Gaps = 8/141 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL L+ E + K+ YN+
Sbjct: 551 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQAQLKELTSAEENIPAKILSYNRA 610
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLET----RRAEAVAWVKELK--RGLAKWNKGGKGAK 337
N+ VA LCNH R P + M L+T ++A+ A +ELK + AK + K K
Sbjct: 611 NRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKK 670
Query: 338 AGAASSPPVEVTQYMPVKPEI 400
A A V+ +K E+
Sbjct: 671 AVEAKKKAVQRIDDQLMKLEV 691
[142][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 73.6 bits (179), Expect = 7e-12
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L + + V K+ YN+
Sbjct: 556 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLNELTNSEDNVPAKILSYNRA 615
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+T+ + E KR L KGAKA A
Sbjct: 616 NRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLVEAKREL-------KGAKADA 665
[143][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/101 (36%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQ 175
I +++ T+LN+YLK + LSAK FRT+NAS+TL E + DP +++DK+ ++NK
Sbjct: 410 IFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEWFREKPVDPKASLSDKLVYFNKA 469
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N VA+LCNH R++P + ++ + + + L+R
Sbjct: 470 NTEVAKLCNHQRSIPKTFHVSVQSIKYKLEDIKRTIDTLRR 510
[144][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/101 (36%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQ 175
I +++ T+LN+YLK + LSAK FRT+NAS+TL E + DP +++DK+ ++NK
Sbjct: 445 IFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEWFREKPVDPKASLSDKLVYFNKA 504
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
N VA+LCNH R++P + ++ + + + L+R
Sbjct: 505 NTEVAKLCNHQRSIPKTFHVSVQSIKYKLEDIKRTIDTLRR 545
[145][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[146][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[147][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[148][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[149][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[150][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[151][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +T +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNEDDTEAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P GH M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKGHAKSMEKLKEK 145
[152][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 73.6 bits (179), Expect = 7e-12
Identities = 42/105 (40%), Positives = 65/105 (61%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ L+ +SLN +L+ LM GL+AK FRT+NAS+TL E L+ +++T KV YN+
Sbjct: 392 DLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRA 451
Query: 176 NKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELKR 298
N+ VA LCNH R +P + M K+ET++A+ EL++
Sbjct: 452 NRAVAVLCNHQRAIPKTFEESMQTLQKKIETKKAQVAEAQVELQK 496
[153][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 73.2 bits (178), Expect = 9e-12
Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L+ +++ K+ YN+
Sbjct: 568 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSLPAKILSYNRA 627
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + E ++ L+ K KGAKA +S
Sbjct: 628 NRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKGAKAEHKAS 680
Query: 356 PPVEVTQYMPVKPEILE 406
+ + + VK + ++
Sbjct: 681 HDDKSKKAVEVKRKAVQ 697
[154][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 9e-12
Identities = 37/88 (42%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +TV +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNAEDTVAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[155][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 73.2 bits (178), Expect = 9e-12
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 3/108 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD---PGETVTDKVAFYNK 172
N+ +SV LND+LK+ M GL+AK FRT+NAS TL + L G +V KV FY+
Sbjct: 380 NLFSDISVDDLNDFLKKQMEGLTAKVFRTYNASFTLQQQLDLGGKLDGHSVQQKVDFYDN 439
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWN 316
NK VA LCNH +T+ + K+ T+ +++EL++ K N
Sbjct: 440 ANKQVAILCNHQKTISKQFELTKKKINTKLECMKTYIQELEQHYKKKN 487
[156][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 72.8 bits (177), Expect = 1e-11
Identities = 36/88 (40%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +T+ +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLTELMDGLTAKVFRTYNASWTLQQQLDELTNADDTIAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P H M KL+ +
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEK 145
[157][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 72.8 bits (177), Expect = 1e-11
Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQ 175
++ RL +LN++L+ LM GL+ K FRT+NAS+TL E L +P + V K+ YN+
Sbjct: 631 DLFDRLDTATLNEHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPDDNVAAKILSYNRA 690
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R + G M KLE +
Sbjct: 691 NRQVAILCNHQRAVSKGFDESMAKLEQK 718
[158][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 72.8 bits (177), Expect = 1e-11
Identities = 38/86 (44%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ ++ +K+ YN N+
Sbjct: 632 IFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKDLKSTGSIAEKIKDYNDANR 691
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 692 KVAILCNHKRTVTASHASQMEKLGDR 717
[159][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 72.8 bits (177), Expect = 1e-11
Identities = 39/87 (44%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
+I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ TV +KV YN N
Sbjct: 625 DIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMARLLKEMKATGTVQEKVKAYNDAN 684
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH RT+ + H + K+ R
Sbjct: 685 REVAILCNHKRTVAASHATSIEKMNER 711
[160][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 72.8 bits (177), Expect = 1e-11
Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ T LN L+ M GL+AK FRT+NAS T+ + L P E TV +KV +N N
Sbjct: 500 DLFDRINPTMLNKQLQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAAN 559
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
+ VA LCNH RT+ GH + K+ + E + LKR
Sbjct: 560 RTVAILCNHQRTVSKGHGSSVQKINDKLKELMWQKIRLKR 599
[161][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 72.4 bits (176), Expect = 1e-11
Identities = 49/141 (34%), Positives = 76/141 (53%), Gaps = 8/141 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL L+ E + K+ YN+
Sbjct: 549 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQAQLKELTSEEENIPAKILSYNRA 608
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLET----RRAEAVAWVKELK--RGLAKWNKGGKGAK 337
N+ VA LCNH R P + M L+T ++ + A +ELK + AK K K K
Sbjct: 609 NRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKK 668
Query: 338 AGAASSPPVEVTQYMPVKPEI 400
A + V+ + +K E+
Sbjct: 669 AVESKKKAVQRIEDQLMKLEV 689
[162][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 72.4 bits (176), Expect = 1e-11
Identities = 49/141 (34%), Positives = 76/141 (53%), Gaps = 8/141 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL L+ E + K+ YN+
Sbjct: 549 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQAQLKELTSEEENIPAKILSYNRA 608
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLET----RRAEAVAWVKELK--RGLAKWNKGGKGAK 337
N+ VA LCNH R P + M L+T ++ + A +ELK + AK K K K
Sbjct: 609 NRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKK 668
Query: 338 AGAASSPPVEVTQYMPVKPEI 400
A + V+ + +K E+
Sbjct: 669 AVESKKKAVQRIEDQLMKLEV 689
[163][TOP]
>UniRef100_C4Q6C8 DNA topoisomerase type I, putative n=2 Tax=Schistosoma mansoni
RepID=C4Q6C8_SCHMA
Length = 587
Score = 72.4 bits (176), Expect = 1e-11
Identities = 38/88 (43%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ T LN YL++LM GL+AK FRT+NAS TL E L+ +P + K+ YN+
Sbjct: 483 DLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRA 542
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P M L+ +
Sbjct: 543 NRAVAVLCNHQRSVPKSFAKSMENLQKK 570
[164][TOP]
>UniRef100_C4Q6C7 DNA topoisomerase type I, putative n=1 Tax=Schistosoma mansoni
RepID=C4Q6C7_SCHMA
Length = 652
Score = 72.4 bits (176), Expect = 1e-11
Identities = 38/88 (43%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ T LN YL++LM GL+AK FRT+NAS TL E L+ +P + K+ YN+
Sbjct: 483 DLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRA 542
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P M L+ +
Sbjct: 543 NRAVAVLCNHQRSVPKSFAKSMENLQKK 570
[165][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 72.4 bits (176), Expect = 1e-11
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L Q MPGL+AK FRT+NAS T++E L+ +KV YN N+
Sbjct: 592 IFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANR 651
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 652 KVAILCNHKRTVGAAHAHQMEKMSER 677
[166][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 72.4 bits (176), Expect = 1e-11
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L Q MPGL+AK FRT+NAS T++E L+ +KV YN N+
Sbjct: 592 IFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANR 651
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 652 KVAILCNHKRTVGAAHAHQMEKMSER 677
[167][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 72.4 bits (176), Expect = 1e-11
Identities = 44/113 (38%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ RL+ LN +L+ +PGLSAK FRT+NAS T+ + L P E +V +KV YN N
Sbjct: 484 DLFDRLTPNILNKHLQNYLPGLSAKVFRTYNASKTMQDQLDLIPNEGSVGEKVVKYNAAN 543
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
+ VA LCNH RT P H + ++ E LKR + + +K K K
Sbjct: 544 REVAILCNHQRTKPKSHDMGVQRISDNIRELFWQKLRLKRMILELDKSLKKTK 596
[168][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 72.4 bits (176), Expect = 1e-11
Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP--GETVTDKVAFYNKQ 175
N+ R++ LN +L M GL+AK FRT+NAS T L + T+ +K+ YNK
Sbjct: 601 NLFDRVTTAGLNKHLTSYMKGLTAKVFRTYNASSTFQRLLDEEDLTNATIQEKINAYNKA 660
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELK 295
N++VA LCNH R P H M K+ + A V K K
Sbjct: 661 NRMVAILCNHQRAAPKTHDQSMEKMRYKAAPVVEMKKNKK 700
[169][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 72.0 bits (175), Expect = 2e-11
Identities = 46/137 (33%), Positives = 77/137 (56%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L+ ++V K+ YN+
Sbjct: 371 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRA 430
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + E ++ L+ K K AKA +S
Sbjct: 431 NRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKAS 483
Query: 356 PPVEVTQYMPVKPEILE 406
+ + + VK + ++
Sbjct: 484 HDDKSKKAVEVKRKAVQ 500
[170][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 72.0 bits (175), Expect = 2e-11
Identities = 46/137 (33%), Positives = 77/137 (56%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L+ ++V K+ YN+
Sbjct: 603 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRA 662
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + E ++ L+ K K AKA +S
Sbjct: 663 NRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKAS 715
Query: 356 PPVEVTQYMPVKPEILE 406
+ + + VK + ++
Sbjct: 716 HDDKSKKAVEVKRKAVQ 732
[171][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 72.0 bits (175), Expect = 2e-11
Identities = 46/137 (33%), Positives = 77/137 (56%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L+ ++V K+ YN+
Sbjct: 565 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + E ++ L+ K K AKA +S
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKAS 677
Query: 356 PPVEVTQYMPVKPEILE 406
+ + + VK + ++
Sbjct: 678 HDDKSKKAVEVKRKAVQ 694
[172][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 72.0 bits (175), Expect = 2e-11
Identities = 46/137 (33%), Positives = 77/137 (56%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L++LM GL+AK FRT+NAS+TL + L+ ++V K+ YN+
Sbjct: 565 DLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 355
N+ VA LCNH R P + M L+T+ + E ++ L+ K K AKA +S
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKAS 677
Query: 356 PPVEVTQYMPVKPEILE 406
+ + + VK + ++
Sbjct: 678 HDDKSKKAVEVKRKAVQ 694
[173][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 72.0 bits (175), Expect = 2e-11
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 563 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 622
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+T+ + K LA + K AKA A
Sbjct: 623 NRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKSAKADA 672
[174][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 71.6 bits (174), Expect = 3e-11
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 8/141 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L+ LM GL+AK FRT+NAS+TL + L+ +P + + K+ YN+
Sbjct: 564 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRA 623
Query: 176 NKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELK--RGLAKWNKGGKGAK 337
N+ VA LCNH R P + M K++ ++ + +ELK + AK + K K
Sbjct: 624 NRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRELKSAKADAKVRRDEKSKK 683
Query: 338 AGAASSPPVEVTQYMPVKPEI 400
A + V+ + +K E+
Sbjct: 684 AVESKKKAVQRIEEQLMKLEV 704
[175][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 71.6 bits (174), Expect = 3e-11
Identities = 41/103 (39%), Positives = 61/103 (59%), Gaps = 5/103 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTL-AECLQGDPGE----TVTDKVAFY 166
+++ + + +NDY KQ M LSAK FRT+NAS+TL E + DP E ++ V FY
Sbjct: 435 DMIFSIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQELCKFDPEEHDISDPSEMVKFY 494
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELK 295
N N+ VA LCNH R P H+ M +L+ + A+ A ++ L+
Sbjct: 495 NDANRRVAILCNHQRAPPKQHEAGMERLKKKLADQEATLRGLE 537
[176][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 71.6 bits (174), Expect = 3e-11
Identities = 41/103 (39%), Positives = 61/103 (59%), Gaps = 5/103 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTL-AECLQGDPGE----TVTDKVAFY 166
+++ + + +NDY KQ M LSAK FRT+NAS+TL E + DP E ++ V FY
Sbjct: 435 DMIFSIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQELCKFDPEEHDISDPSEMVKFY 494
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELK 295
N N+ VA LCNH R P H+ M +L+ + A+ A ++ L+
Sbjct: 495 NDANRRVAILCNHQRAPPKQHEAGMERLKKKLADQEATLRGLE 537
[177][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 71.6 bits (174), Expect = 3e-11
Identities = 38/111 (34%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQ 175
++ RL+ +N +L +LM GL+AK FRT+NAS TL + L + +++ +K+ YN+
Sbjct: 58 DLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDSLAEKILSYNRA 117
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
N+ VA LCNH R++P H M KL+ + + + + +R + K K
Sbjct: 118 NRAVAILCNHQRSVPKSHAKSMEKLKEKIDQKREQIADAQRQVKDAQKDAK 168
[178][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 71.6 bits (174), Expect = 3e-11
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
+I RL + LN +L+ MPGL+AK FRT+NAS T+ + L P E TV +K+ +N N
Sbjct: 484 DIFDRLDPSVLNKHLQNYMPGLTAKVFRTYNASKTMDDQLALIPNEGTVAEKLVKFNAAN 543
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH +T+ H + K+E R E V W K
Sbjct: 544 RAVAILCNHQKTVSKTHGESVGKIEDRINE-VVWQK 578
[179][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 71.2 bits (173), Expect = 3e-11
Identities = 43/117 (36%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L+ LM GL+AK FRT+NAS+TL + L+ +P + + K+ YN+
Sbjct: 573 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRA 632
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 633 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRELKSAKADA 682
[180][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 71.2 bits (173), Expect = 3e-11
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 2/110 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQN 178
+ RL + LN +L LMPGL+AK FRT+NAS+TL E L+ + ++V +K+ YN+ N
Sbjct: 430 LFDRLYTSMLNKHLSSLMPGLTAKVFRTYNASITLQEQLKELTNKSDSVAEKLLSYNRAN 489
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGK 328
+ VA LCNH R P M L+++ + K GL + K K
Sbjct: 490 RAVAILCNHQRAPPKTFDQSMATLQSKIDARKEQLALAKSGLKQAKKEAK 539
[181][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 71.2 bits (173), Expect = 3e-11
Identities = 38/86 (44%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T+A L+ T+ +K+ YN N+
Sbjct: 630 IFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANR 689
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 690 KVAILCNHKRTVTASHASQMEKLGDR 715
[182][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 71.2 bits (173), Expect = 3e-11
Identities = 38/86 (44%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T+A L+ T+ +K+ YN N+
Sbjct: 630 IFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANR 689
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M KL R
Sbjct: 690 KVAILCNHKRTVTASHASQMEKLGDR 715
[183][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 71.2 bits (173), Expect = 3e-11
Identities = 36/86 (41%), Positives = 55/86 (63%), Gaps = 2/86 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGETVT--DKVAFYNKQ 175
+I RL+ T LN +L MPGLSAK FRT+NAS T+++ L+ ++ +K+ YN
Sbjct: 628 DIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMSDLLKKLKNSDISMQEKIKLYNDC 687
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLE 253
N+ VA LCNH RT+ + H+ + K++
Sbjct: 688 NRKVAILCNHKRTVGASHEAAIEKMD 713
[184][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 71.2 bits (173), Expect = 3e-11
Identities = 36/86 (41%), Positives = 55/86 (63%), Gaps = 2/86 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGETVT--DKVAFYNKQ 175
+I RL+ T LN +L MPGLSAK FRT+NAS T+++ L+ ++ +K+ YN
Sbjct: 629 DIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMSDLLKKLKNSDISMQEKIKLYNDC 688
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLE 253
N+ VA LCNH RT+ + H+ + K++
Sbjct: 689 NRKVAILCNHKRTVGASHEAAIEKMD 714
[185][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 71.2 bits (173), Expect = 3e-11
Identities = 46/117 (39%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E V K+ YN+
Sbjct: 565 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA K K AKA A
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARKDLKSAKADA 674
[186][TOP]
>UniRef100_Q5BXE0 SJCHGC03473 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BXE0_SCHJA
Length = 238
Score = 70.9 bits (172), Expect = 4e-11
Identities = 37/88 (42%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN YL++LM GL+AK FRT+NAS TL E L+ +P + K+ YN+
Sbjct: 134 DLFDRLNTSVLNQYLRELMDGLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRA 193
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++P M L+ +
Sbjct: 194 NRAVAVLCNHQRSVPKSFAKSMENLQKK 221
[187][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 70.9 bits (172), Expect = 4e-11
Identities = 37/87 (42%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQN 178
+I RL+ ++LN +L MPGL+AK FRT+NAS T+A L+ T+ +KV YN N
Sbjct: 607 DIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMARLLKSLKATGTIQEKVKAYNDAN 666
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH RT+ + H + K+ +
Sbjct: 667 REVAILCNHKRTVAATHGASIDKMNEK 693
[188][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 563 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 622
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 623 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 672
[189][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 565 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 674
[190][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 802 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 861
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 862 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 911
[191][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 550 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 609
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 610 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 659
[192][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 567 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 626
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 627 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 676
[193][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 358 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 417
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 418 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 467
[194][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 70.5 bits (171), Expect = 6e-11
Identities = 45/116 (38%), Positives = 64/116 (55%), Gaps = 5/116 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL-----QGDPGETVTDKVAFY 166
++ R+ +SLN+YLK M GL+AK FRT+NAS TL + L +G + DK+ FY
Sbjct: 492 DLFDRIDASSLNEYLKSQMEGLTAKVFRTYNASHTLQKELDKADEEGLDKMDLKDKLNFY 551
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGA 334
++ N+ VA LCNH +T+ + K+E R + KEL L K K G A
Sbjct: 552 DEANRNVAILCNHQKTVGKNFDVMVGKMEQRINVYKDYEKELHTHLNKCKKNGVNA 607
[195][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 70.5 bits (171), Expect = 6e-11
Identities = 45/117 (38%), Positives = 63/117 (53%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT NAS+TL + L+ P E + K+ YN+
Sbjct: 563 DLFDRLNTGILNKHLQDLMEGLTAKVFRTHNASITLQQQLKELTAPDENIPAKILSYNRA 622
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+T+ + K LA + K AKA A
Sbjct: 623 NRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKSAKADA 672
[196][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 70.5 bits (171), Expect = 6e-11
Identities = 38/96 (39%), Positives = 59/96 (61%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ +LN +L+ M GL+AK FRT+NAS T+ + + P E TV +KV YN N
Sbjct: 486 DLFDRITPATLNKHLQAYMKGLTAKVFRTYNASKTMQDQMDLIPNEGTVAEKVMKYNAAN 545
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H+ + K++ + E + W K
Sbjct: 546 RTVAILCNHQRTVSKAHQNSVGKIQEKIKE-MEWQK 580
[197][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 70.5 bits (171), Expect = 6e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E + K+ YN+
Sbjct: 565 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKSAKADA 674
[198][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 70.1 bits (170), Expect = 7e-11
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E V K+ YN+
Sbjct: 556 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRA 615
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 616 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKSAKADA 665
[199][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 70.1 bits (170), Expect = 7e-11
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E V K+ YN+
Sbjct: 565 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKSAKADA 674
[200][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 70.1 bits (170), Expect = 7e-11
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E V K+ YN+
Sbjct: 565 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRA 624
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 625 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKSAKADA 674
[201][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 69.7 bits (169), Expect = 1e-10
Identities = 40/91 (43%), Positives = 54/91 (59%), Gaps = 5/91 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ---GDPGE--TVTDKVAFY 166
++ RL+ + LN +L M GL+AK FRT+NAS T++ L DP TV +KV Y
Sbjct: 624 DLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLY 683
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N N+ VA LCNH RT+ + H+ M KL R
Sbjct: 684 NDCNREVAILCNHKRTVGASHEQQMAKLGDR 714
[202][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 69.7 bits (169), Expect = 1e-10
Identities = 37/86 (43%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T++ L+ T+ +KV YN N+
Sbjct: 602 IFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMSTLLKDMKATGTIAEKVKAYNDANR 661
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 662 QVAILCNHKRTVTASHANQMEKMGER 687
[203][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 69.7 bits (169), Expect = 1e-10
Identities = 40/91 (43%), Positives = 54/91 (59%), Gaps = 5/91 (5%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ---GDPGE--TVTDKVAFY 166
++ RL+ + LN +L M GL+AK FRT+NAS T++ L DP TV +KV Y
Sbjct: 623 DLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLY 682
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N N+ VA LCNH RT+ + H+ M KL R
Sbjct: 683 NDCNREVAILCNHKRTVGASHEQQMAKLGDR 713
[204][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 69.7 bits (169), Expect = 1e-10
Identities = 37/86 (43%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T++ L+ T+ +KV YN N+
Sbjct: 602 IFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMSTLLKDMKATGTIAEKVKAYNDANR 661
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 662 QVAILCNHKRTVTASHANQMEKMGER 687
[205][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 69.3 bits (168), Expect = 1e-10
Identities = 49/147 (33%), Positives = 71/147 (48%), Gaps = 18/147 (12%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG--------------DPGET 142
+ RL+ + LN +L LMPGL+AK FRT+NAS+TL + L+ ++
Sbjct: 407 LFDRLNTSLLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELTNVIILFFFPCRLPESDS 466
Query: 143 VTDKVAFYNKQNKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELKRGLAK 310
V +K+ YN+ N+ VA LCNH R P M K+E R+ + V ELK+
Sbjct: 467 VAEKLLSYNRANRAVAILCNHQRAPPKTFDQSMANLQSKIEARKEQLVLAKSELKQA--- 523
Query: 311 WNKGGKGAKAGAASSPPVEVTQYMPVK 391
K K + A + V + M VK
Sbjct: 524 -KKEAKAKGSADAKLQALVVRKKMAVK 549
[206][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 69.3 bits (168), Expect = 1e-10
Identities = 38/89 (42%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ---GDPGETVTDKVAFYNK 172
+I RL+ + LN +L MPGL+AK FRT+NAS T++ LQ + +KV YN
Sbjct: 622 DIFDRLTTSQLNKHLSSYMPGLTAKVFRTYNASYTMSTLLQKLHSKKNISDAEKVKIYND 681
Query: 173 QNKVVAELCNHVRTLPSGHKGHMHKLETR 259
N+ VA LCNH R++ + H M KL R
Sbjct: 682 CNRQVAILCNHKRSVGASHDAQMKKLGDR 710
[207][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 68.9 bits (167), Expect = 2e-10
Identities = 44/127 (34%), Positives = 72/127 (56%), Gaps = 2/127 (1%)
Frame = +2
Query: 32 LNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNH 205
LN +L++LM GL+AK FRT+NAS+TL + L+ +++ K+ YN+ N+ VA LCNH
Sbjct: 591 LNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNH 650
Query: 206 VRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMP 385
R P + M L+T+ + E ++ L+ K KGAKA +S + + +
Sbjct: 651 QRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKGAKAEHKASHDDKSKKAVE 703
Query: 386 VKPEILE 406
VK + ++
Sbjct: 704 VKRKAVQ 710
[208][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 68.9 bits (167), Expect = 2e-10
Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQN 178
+I + +N +L+ LMPGL+ K FRT+NAS+TL L+ +T K A Y+ N
Sbjct: 296 DIFDHVDPQKVNAHLQTLMPGLTIKVFRTYNASITLDRLLKDTKKNDTTLQKKATYDAAN 355
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKR 298
K VA LCNH + + H M KL ++ + V E+K+
Sbjct: 356 KEVAILCNHQKGVSKAHDAQMEKLAEKKKDLAKQVAEMKK 395
[209][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 68.9 bits (167), Expect = 2e-10
Identities = 38/86 (44%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNK 181
I RL+ ++LN +L Q MPGL+AK FRT+NAS T++E L+ +KV YN N+
Sbjct: 592 IFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANR 651
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + + M K+ R
Sbjct: 652 KVAILCNHKRTVGAVTRDQMEKMSER 677
[210][TOP]
>UniRef100_UPI000187C7E9 hypothetical protein MPER_03600 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187C7E9
Length = 238
Score = 68.2 bits (165), Expect = 3e-10
Identities = 36/85 (42%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGD--PGETVTDKVAFYNKQ 175
N+ R++ LN +L M GL+AK FRT+NAS T L G T+ +K+ YNK
Sbjct: 31 NLFDRVNTAMLNKHLNSEMKGLTAKVFRTYNASHTFQTLLDESHLEGATLQEKLNAYNKA 90
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKL 250
N++VA LCNH R++P H M K+
Sbjct: 91 NRLVAILCNHQRSVPKTHDQSMQKM 115
[211][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 68.2 bits (165), Expect = 3e-10
Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T++ L+ + +KV YN N+
Sbjct: 605 IFDRLTTSALNKHLSAYMQGLTAKVFRTYNASHTMSTLLKDMKATGNIAEKVKAYNDANR 664
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 665 KVAILCNHKRTVAASHANQMEKMSER 690
[212][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum
RepID=TOP1_DICDI
Length = 893
Score = 68.2 bits (165), Expect = 3e-10
Identities = 36/87 (41%), Positives = 55/87 (63%), Gaps = 3/87 (3%)
Frame = +2
Query: 17 LSVTSLNDYLKQLMPGLSAKEFRTFNASVTL---AECLQGDPGETVTDKVAFYNKQNKVV 187
L+VT LN++LK+ M GLSAK FRT+NAS+TL + + +++ +K+ FYN+ N+ V
Sbjct: 656 LTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKELDKMDTKEFQSIDEKILFYNRCNREV 715
Query: 188 AELCNHVRTLPSGHKGHMHKLETRRAE 268
A LCNH + P M K++ + E
Sbjct: 716 AILCNHQKAPPKNLAETMSKIDEKIQE 742
[213][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 67.8 bits (164), Expect = 4e-10
Identities = 43/116 (37%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ-GDPGETVTDKVAFYNKQN 178
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + + E + K+ YN+ N
Sbjct: 547 DLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQVSFFTADENIPAKILSYNRAN 606
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
+ VA LCNH R P + M L+T+ + K LA + K AKA A
Sbjct: 607 RAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKSAKADA 655
[214][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 67.8 bits (164), Expect = 4e-10
Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQ 175
++ R+S +LN L + M GL+AK FRTFNAS TL + L + TV +K+ YN+
Sbjct: 398 DLFDRISTVNLNKALTESMSGLTAKVFRTFNASTTLQDQLNKLTSDDCTVEEKILSYNRA 457
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAAS 352
N+ VA LCNH R P + M L+ + + ++E ++ L + + K + +S
Sbjct: 458 NRAVAILCNHQRAAPKTFEKSMQLLQEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSS 516
[215][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 67.8 bits (164), Expect = 4e-10
Identities = 42/111 (37%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ-----GDPGETVTDKVAFY 166
+I + T +N +L+ LMPGL+ K FRT+NAS TL + L+ GD TV K A Y
Sbjct: 451 DIFDHIDPTKVNKHLQTLMPGLTIKVFRTYNASYTLNKLLKETTPAGD--STVPMKKAAY 508
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNK 319
+ NK VA LCNH + + H M KL+ ++ + L+R NK
Sbjct: 509 DAANKEVAVLCNHQKGVSKAHDAQMEKLQDKKKIIEKEIAALRRDKKDTNK 559
[216][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 67.8 bits (164), Expect = 4e-10
Identities = 38/104 (36%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
+I R++ + +N L+ M GL+AK FRT+NAS T+ + L P E T +KV +N N
Sbjct: 571 DIFDRINPSMVNKQLQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTAAEKVVKFNAAN 630
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAK 310
+ VA LCNH RT+ H + K+ + E + LK+ + K
Sbjct: 631 RTVAILCNHQRTVSKNHGNSVQKINDKLRELIWQKIRLKKMILK 674
[217][TOP]
>UniRef100_Q941M6 Topoisomerase I (Fragment) n=1 Tax=Oryza sativa RepID=Q941M6_ORYSA
Length = 105
Score = 67.4 bits (163), Expect = 5e-10
Identities = 34/69 (49%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 37 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 96
Query: 179 KVVAELCNH 205
K VA LCNH
Sbjct: 97 KEVAILCNH 105
[218][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 67.4 bits (163), Expect = 5e-10
Identities = 49/161 (30%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLA------ECLQGDPGETVTDKVAFY 166
+ H ++ T LN++LKQ M GLSAK FRT+NAS TL E T ++KV Y
Sbjct: 379 VFHVINPTMLNNHLKQFMDGLSAKVFRTYNASKTLQTELRKYEVSPAWRNLTASEKVVEY 438
Query: 167 NKQNKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N N+ VA LCNH R++ + + + + K+LK+ + K G+ K
Sbjct: 439 NNANREVAILCNHQRSVSKAQETQLENITAKVGMLKKQKKDLKK-ILKLLTAGEADKIPT 497
Query: 347 ASSPPVEVTQYMPVKPEI----LESMTADEKAQERKRAADL 457
SP + + K E + M D K ++ + L
Sbjct: 498 KKSPQTMTDEQVVKKIEAWNGKISKMEMDLKHKDDNKEVSL 538
[219][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 67.4 bits (163), Expect = 5e-10
Identities = 37/86 (43%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
I RL+ ++LN +L M GL+AK FRT+NAS T+A L+ +KV YN N+
Sbjct: 607 IFDRLTTSALNKHLSTYMQGLTAKVFRTYNASYTMATLLKDMKATGNNAEKVKAYNDANR 666
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETR 259
VA LCNH RT+ + H M K+ R
Sbjct: 667 RVAILCNHKRTVTASHANQMEKMSER 692
[220][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 67.0 bits (162), Expect = 6e-10
Identities = 40/113 (35%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQN 178
+I + + +N +L+ LMPGL+ K FRT+NAS+TL L D T K A Y+ N
Sbjct: 576 DIFDLIDPSKVNAHLQTLMPGLTIKVFRTYNASITLDSLLADTDTNLTTLQKKAKYDAAN 635
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 337
K VA LCNH + + H M KL ++ + + ++K+ NK K K
Sbjct: 636 KEVAILCNHQKGVSKAHDEQMGKLNDKKKDLAKQITDMKK-----NKDDKNQK 683
[221][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 67.0 bits (162), Expect = 6e-10
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 12/147 (8%)
Frame = +2
Query: 32 LNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--------GDPGETVTDKVAFYNKQNKVV 187
LN LK +M GLS K FRT+NAS+ L L +TV K Y+ NK V
Sbjct: 385 LNKELKNIMDGLSVKVFRTYNASIVLDRLLSEWEATKKGHSTAQTVDQKKVDYDIANKEV 444
Query: 188 AELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG----GKGAKAGAASS 355
A LCNH R++P H M K++ + A + EL+ L KG K K GA +
Sbjct: 445 AILCNHQRSVPKTHTNQMEKIQEKLAGMNKELAELEDELRAAQKGKAENKKANKCGAPTI 504
Query: 356 PPVEVTQYMPVKPEILESMTADEKAQE 436
P + + K + + + +++E
Sbjct: 505 LPWALNSKIDKKKQAIAKVELQARSKE 531
[222][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 66.6 bits (161), Expect = 8e-10
Identities = 47/143 (32%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLA----ECLQGDPGETVTDKVAFYN 169
++ RL+ + LN +L+ LM GL+AK FRT+NAS+TL E GD + V K+ YN
Sbjct: 582 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLNELTNGD--DNVPAKILSYN 639
Query: 170 KQNKVVAELCNHVRTLPSGHKGHM----HKLETRRAEAVAWVKELK--RGLAKWNKGGKG 331
+ N+ VA LCNH R P + M K++ ++ + + +ELK + AK + K
Sbjct: 640 RANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLMDARRELKSAKADAKVKRDEKS 699
Query: 332 AKAGAASSPPVEVTQYMPVKPEI 400
K + V+ + +K E+
Sbjct: 700 KKLVESKKKAVQRVEEQLMKLEV 722
[223][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 66.6 bits (161), Expect = 8e-10
Identities = 43/117 (36%), Positives = 63/117 (53%), Gaps = 2/117 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ + LN +L+ LM GL+AK FRT+NAS+TL + L + + V K+ YN+
Sbjct: 619 DLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRA 678
Query: 176 NKVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 346
N+ VA LCNH R P + M L+ + + K LA + K AKA A
Sbjct: 679 NRAVAILCNHQRAPPKTFEKSMMNLQGK-------IDAKKDQLADARREFKSAKADA 728
[224][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 65.5 bits (158), Expect = 2e-09
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R+S LN + M GL+AK FRT+NAS T+ + L P E TV +KV +N N
Sbjct: 511 DLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAAN 570
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + K+ + E + W K
Sbjct: 571 RTVAILCNHQRTVSKTHGSSVQKIHDKLKE-LEWHK 605
[225][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 65.5 bits (158), Expect = 2e-09
Identities = 40/99 (40%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQN 178
+I ++ + +N +L+ LMPGL+ K FRT+NAS L + L+ +P +TV K A Y+ N
Sbjct: 504 DIFDQIDPSKVNKHLQTLMPGLTIKVFRTYNASFVLNKLLKDTNPRDTVPLKKAAYDAAN 563
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELK 295
K VA LCNH + H M KL ++ A KELK
Sbjct: 564 KEVAVLCNHQKGESKAHGAQMEKLVDKKK---AMEKELK 599
[226][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 65.5 bits (158), Expect = 2e-09
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R+S LN + M GL+AK FRT+NAS T+ + L P E TV +KV +N N
Sbjct: 511 DLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAAN 570
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + K+ + E + W K
Sbjct: 571 RTVAILCNHQRTVSKTHGSSVQKIHDKLKE-LEWHK 605
[227][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 65.5 bits (158), Expect = 2e-09
Identities = 40/102 (39%), Positives = 58/102 (56%), Gaps = 2/102 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL LN +L+ MPGL+AK FRT+NAS T+ + L + +V +K+ YN N+
Sbjct: 521 LFDRLDPPILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIVNKGSVAEKMLRYNAANR 580
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGL 304
VA LCNH R++ GH + K + E + W K LKR +
Sbjct: 581 TVAILCNHQRSVGKGHAEAVRK-ANEKIEELEWQKIRLKRAI 621
[228][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 64.7 bits (156), Expect = 3e-09
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Frame = +2
Query: 5 ILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNK 181
+ RL + LN +L+ M GL+AK FRT+NAS T+ + L E +V +K+ YN N+
Sbjct: 565 LFDRLDPSVLNKHLQHYMQGLTAKVFRTYNASKTMQDQLDLIKNEGSVAEKILKYNAANR 624
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK-ELKRGLAKWNK 319
VA LCNH R++ H + K + + E + W K LKR + + +K
Sbjct: 625 TVAILCNHQRSVAKTHAQSVQK-ASDKIEELEWQKVRLKRAILQLDK 670
[229][TOP]
>UniRef100_Q941M5 Topoisomerase I (Fragment) n=1 Tax=Spinacia oleracea
RepID=Q941M5_SPIOL
Length = 102
Score = 64.3 bits (155), Expect = 4e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 1/68 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ L + LN +LK+L+PGL+AK FRT+NAS+TL E L + + VT K+ Y K N
Sbjct: 35 DLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKAN 94
Query: 179 KVVAELCN 202
K VA LCN
Sbjct: 95 KEVAILCN 102
[230][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 63.9 bits (154), Expect = 5e-09
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R+S LN + M GL+AK FRT+NAS T+ + + P E TV +KV +N N
Sbjct: 476 DLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKVVRFNAAN 535
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H GH + R + + W K
Sbjct: 536 RTVAILCNHQRTVSKTH-GHSVQRIHDRIKEMMWQK 570
[231][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 63.9 bits (154), Expect = 5e-09
Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 3/111 (2%)
Frame = +2
Query: 29 SLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ---GDPGETVTDKVAFYNKQNKVVAELC 199
+LN L + M GL+AK FRTFNAS TL + L D G TV +K+ YN+ N+ VA LC
Sbjct: 3 NLNKALTESMSGLTAKVFRTFNASTTLQDQLNKLTSDDG-TVEEKILSYNRANRAVAILC 61
Query: 200 NHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAAS 352
NH R P + M L+ + + ++E ++ L + + K + +S
Sbjct: 62 NHQRAAPKTFEKSMQLLQEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSS 112
[232][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 63.9 bits (154), Expect = 5e-09
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R+S LN + M GL+AK FRT+NAS T+ + + P E TV +KV +N N
Sbjct: 476 DLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKVVRFNAAN 535
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H GH + R + + W K
Sbjct: 536 RTVAILCNHQRTVSKTH-GHSVQRIHDRIKEMMWQK 570
[233][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 63.5 bits (153), Expect = 7e-09
Identities = 38/107 (35%), Positives = 54/107 (50%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNK 181
++ +L + LN +LK+LMPGL+AK FRT+NAS+TL E
Sbjct: 1266 DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDE---------------------- 1303
Query: 182 VVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVKELKRGLAKWNKG 322
+VA +CNH RT+ H M +L + E + LK LA+ KG
Sbjct: 1304 MVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKG 1350
[234][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 63.2 bits (152), Expect = 9e-09
Identities = 35/96 (36%), Positives = 55/96 (57%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ + +N L+ M GL+AK FRT+NAS T+ + + E TV +KV +N N
Sbjct: 499 DLFDRINPSLVNKQLQNYMKGLTAKVFRTYNASKTMQDQIDLIENEGTVAEKVVKFNAAN 558
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + K+ + E + W K
Sbjct: 559 RTVAILCNHQRTVSKNHSNTVQKINDKLKE-LMWQK 593
[235][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 61.2 bits (147), Expect = 3e-08
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN +L+ LM GL+AK FRT+NAS+TL + L+ P E V + YN+
Sbjct: 561 DLFDRLNTGILNKHLQGLMEGLTAKVFRTYNASITLQQQLKELTAPDENV-PAILSYNRA 619
Query: 176 NKVVAELCNHVRTLPSGHKGHM---HKLETRRAEAVAWVKELKRGLA 307
N+ VA LCNH R P + M K++ ++ + K+LK A
Sbjct: 620 NRAVAILCNHQRAPPKTFEKSMMNQSKIDAKKDQLADARKDLKSAKA 666
[236][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 61.2 bits (147), Expect = 3e-08
Identities = 35/96 (36%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ + +N L+ M GL+AK FRT+NAS T+ + + E TV +KVA +N N
Sbjct: 502 DLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAAN 561
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + ++ + E + W K
Sbjct: 562 RTVAILCNHQRTVSKTHGDSVQRINDKLKEFM-WQK 596
[237][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 61.2 bits (147), Expect = 3e-08
Identities = 35/96 (36%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ + +N L+ M GL+AK FRT+NAS T+ + + E TV +KVA +N N
Sbjct: 502 DLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAAN 561
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + ++ + E + W K
Sbjct: 562 RTVAILCNHQRTVSKTHGDSVQRINDKLKEFM-WQK 596
[238][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 60.1 bits (144), Expect = 8e-08
Identities = 41/108 (37%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTL------AECLQGDPGETVTDKVAF 163
++ L+ T LN +LK +M GL+AK FRT+NAS TL E G T +KV
Sbjct: 312 DVFSDLTPTILNAHLKSIMEGLTAKVFRTYNASKTLQDELTKTETAAGWKRLTAAEKVVE 371
Query: 164 YNKQNKVVAELCNHVRTLPSGHKGHMH----KLETRRAEAVAWVKELK 295
YN N+ VA LCNH R++ + + KL+T + A K LK
Sbjct: 372 YNNANREVAILCNHQRSVSKAQETTLENLGDKLQTLNDQKKALKKILK 419
[239][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 60.1 bits (144), Expect = 8e-08
Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ + +N L+ M GL+AK FRT+NAS T+ + + E TV +KVA +N N
Sbjct: 500 DLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAAN 559
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETR 259
+ VA LCNH RT+ H + ++ +
Sbjct: 560 RTVAILCNHQRTVSKTHGDSVQRINDK 586
[240][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 59.3 bits (142), Expect = 1e-07
Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQN 178
++ R++ + +N L+ M GL+AK FRT+NAS T+ + + E TV +KV +N N
Sbjct: 499 DLFDRINPSLVNRQLQYYMKGLTAKVFRTYNASKTMQDQIDLIENEGTVAEKVVKFNAAN 558
Query: 179 KVVAELCNHVRTLPSGHKGHMHKLETRRAEAVAWVK 286
+ VA LCNH RT+ H + ++ + E + W K
Sbjct: 559 RTVAILCNHQRTVSKTHGDSIQRINDKLKEFM-WQK 593
[241][TOP]
>UniRef100_Q1WWG8 IP16129p (Fragment) n=1 Tax=Drosophila melanogaster
RepID=Q1WWG8_DROME
Length = 382
Score = 57.0 bits (136), Expect = 6e-07
Identities = 30/63 (47%), Positives = 42/63 (66%), Gaps = 2/63 (3%)
Frame = +2
Query: 2 NILHRLSVTSLNDYLKQLMPGLSAKEFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQ 175
++ RL+ LN++LK+LM GL+AK FRT+NAS TL L DP TV +K+ YN+
Sbjct: 300 DLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRA 359
Query: 176 NKV 184
N+V
Sbjct: 360 NRV 362
[242][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 55.8 bits (133), Expect = 1e-06
Identities = 31/61 (50%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +2
Query: 80 FRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGHMHKLET 256
FRT+NAS T+A L Q TV +KV YN N+ VA LCNH RT+ +GH M KL
Sbjct: 635 FRTYNASYTMATLLKQMQATGTVHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLSE 694
Query: 257 R 259
R
Sbjct: 695 R 695