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[1][TOP]
>UniRef100_Q7XZ18 Sonic hedgehog protein (Fragment) n=1 Tax=Griffithsia japonica
RepID=Q7XZ18_GRIJA
Length = 155
Score = 79.0 bits (193), Expect = 2e-13
Identities = 53/122 (43%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
Frame = +2
Query: 152 IGDRVRAADGSFSDVFLFTHADPTAKSTFVTLTTAAG-VLTVTPGHYVLVNEGVRTAASA 328
+GDRV G FS LF+H D + + FV ++TA G + T GHY+ VN G A +
Sbjct: 1 LGDRVHVGGGEFSPRVLFSHRDASTRHAFVQVSTACGRSVAATHGHYLYVN-GRLAIAGS 59
Query: 329 VVVGDVLSYMPPAGCAAAAAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTX 508
V VGD L A P VT V GLYNPQTL G IVVD A TFT
Sbjct: 60 VKVGDRLQ---------DAHGAPLDVTKVEVVTKTGLYNPQTLHGDIVVDSVRASTFTKA 110
Query: 509 VE 514
VE
Sbjct: 111 VE 112
[2][TOP]
>UniRef100_B4JTF5 Protein hedgehog C-product n=1 Tax=Drosophila grimshawi
RepID=HH_DROGR
Length = 479
Score = 68.9 bits (167), Expect = 2e-10
Identities = 52/153 (33%), Positives = 71/153 (46%), Gaps = 7/153 (4%)
Frame = +2
Query: 53 ESPESTDDDSECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADP 220
+S S CF ++ ++E GA K + +LAIGDRV + D +S+V LF +
Sbjct: 247 DSSSSISHVHGCFTPESTAQLESGAKKPLGELAIGDRVLSMDAKGQAVYSEVILFMDRNL 306
Query: 221 TAKSTFVTLTTAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDV--LSYMPPAGCAAAAAA 391
TFV L T G VLTVTP H + V + R V V L+Y+ A
Sbjct: 307 EQMETFVQLHTDGGAVLTVTPAHLITVWQPERQTLDFVFADHVEELNYVLVVDDATGGEL 366
Query: 392 TPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
P V V +G+ P T G+IVV+ AA
Sbjct: 367 RPQRVLRVSSVRRRGVVAPLTREGTIVVNSVAA 399
[3][TOP]
>UniRef100_UPI00017B4E83 UPI00017B4E83 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4E83
Length = 209
Score = 68.6 bits (166), Expect = 2e-10
Identities = 57/145 (39%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA-ADGS---FSDVFLFTHADPTAKSTFVTLTT 253
CFP ASV +EGG TKA+ DL G+RV A AD +S V F DP A F TL T
Sbjct: 1 CFPGEASVALEGGGTKAVRDLQPGERVLALADAGELVYSQVLAFLDHDPGAWKLFYTLHT 60
Query: 254 AAGV-LTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG--CAAAAAATPAVVTATGRV 424
AG L +T H + V EG + S P G A PA ++ RV
Sbjct: 61 RAGPRLALTAAHLLFVAEG--NCSEGAERPPAPSRSRPGGPVRAGVPGPWPARLSRITRV 118
Query: 425 V---AKGLYNPQTLVGSIVVDGFAA 490
A+G + P T G++VVDG AA
Sbjct: 119 TLRGARGAFAPLTQQGTLVVDGVAA 143
[4][TOP]
>UniRef100_UPI00017B3FB9 UPI00017B3FB9 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3FB9
Length = 415
Score = 66.6 bits (161), Expect = 9e-10
Identities = 52/147 (35%), Positives = 68/147 (46%), Gaps = 12/147 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-----FSDVFLFTHADPTAKSTFVTLT 250
CF V +EG TK M DL GDRV A+ G +S V F P A S F T+
Sbjct: 203 CFHGDTQVILEGSVTKPMRDLRPGDRVLASSGGGGPLVYSSVLSFLDRQPNATSVFYTIG 262
Query: 251 TAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAA------ATPAVVT 409
T AG +T+T H + V +G R++ + S + P C + AT + VT
Sbjct: 263 TDAGHRITLTAAHLIYVTDGGRSSRDRGLRIVFASEVRPGQCVLTSGGKLGSPATFSPVT 322
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+ GLY P T GSIVV+G A
Sbjct: 323 FVHVRRSTGLYAPLTEHGSIVVNGVLA 349
[5][TOP]
>UniRef100_UPI00017B1C47 UPI00017B1C47 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1C47
Length = 409
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP A V + GG K+++ L GDRV A + FS V +F H DP +KS F++L T
Sbjct: 199 CFPGWARVTLPGGFQKSLSSLTPGDRVMALSETGQVVFSPVLMFLHRDPESKSRFLSLQT 258
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAA----TPAVVTATG 418
G L VTP H+++ ++ S S C AA P+ + +
Sbjct: 259 EDGHRLAVTP-HHLVFSDAYCRPDSRQYRAQFASRARTGTCIVVLAAEGQLRPSRIVSVS 317
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
G+Y P T G+++VDG A ++
Sbjct: 318 EEENTGVYAPLTEAGNVLVDGVLASSY 344
[6][TOP]
>UniRef100_UPI00017B1C46 UPI00017B1C46 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1C46
Length = 442
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP A V + GG K+++ L GDRV A + FS V +F H DP +KS F++L T
Sbjct: 201 CFPGWARVTLPGGFQKSLSSLTPGDRVMALSETGQVVFSPVLMFLHRDPESKSRFLSLQT 260
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAA----TPAVVTATG 418
G L VTP H+++ ++ S S C AA P+ + +
Sbjct: 261 EDGHRLAVTP-HHLVFSDAYCRPDSRQYRAQFASRARTGTCIVVLAAEGQLRPSRIVSVS 319
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
G+Y P T G+++VDG A ++
Sbjct: 320 EEENTGVYAPLTEAGNVLVDGVLASSY 346
[7][TOP]
>UniRef100_UPI000065E181 UPI000065E181 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI000065E181
Length = 465
Score = 66.2 bits (160), Expect = 1e-09
Identities = 50/151 (33%), Positives = 73/151 (48%), Gaps = 16/151 (10%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-------FSDVFLFTHADPTAKSTFVT 244
CFP A V +E G TK+++DL G+RV A GS +S+V F DP+ F T
Sbjct: 253 CFPGEALVTLESGGTKSISDLRPGERVLALAGSDGAAGLVYSEVLAFLDRDPSTWKLFYT 312
Query: 245 LTTAAGV-LTVTPGHYVLVNEGVRTAASAVVVGDV----LSYMPPAGCAAAA----AATP 397
L T AG L++T H + V+EG + + G + S+ P C + AA
Sbjct: 313 LHTRAGPRLSLTAAHLLFVSEGNCSEGAEPSQGTLKTVYASHASPGQCVLVSQGHGAAFL 372
Query: 398 AVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+ +T +G + P T G++VVD AA
Sbjct: 373 SQITRVAVREGRGAFAPLTQQGTLVVDHVAA 403
[8][TOP]
>UniRef100_Q4RW16 Chromosome 9 SCAF14991, whole genome shotgun sequence n=1
Tax=Tetraodon nigroviridis RepID=Q4RW16_TETNG
Length = 551
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP A V + GG K+++ L GDRV A + FS V +F H DP +KS F++L T
Sbjct: 201 CFPGWARVTLPGGFQKSLSSLTPGDRVMALSETGQVVFSPVLMFLHRDPESKSRFLSLQT 260
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAA----TPAVVTATG 418
G L VTP H+++ ++ S S C AA P+ + +
Sbjct: 261 EDGHRLAVTP-HHLVFSDAYCRPDSRQYRAQFASRARTGTCIVVLAAEGQLRPSRIVSVS 319
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
G+Y P T G+++VDG A ++
Sbjct: 320 EEENTGVYAPLTEAGNVLVDGVLASSY 346
[9][TOP]
>UniRef100_Q7PXI1 AGAP001412-PA (Fragment) n=1 Tax=Anopheles gambiae
RepID=Q7PXI1_ANOGA
Length = 406
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
Frame = +2
Query: 80 SECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTL 247
S CF ++V E G + +++L IG+RV+A D + FS+V +F D + FVT+
Sbjct: 201 SGCFTGDSTVLTEAGVHRKLSELRIGERVQAVDAAGRTVFSEVLMFMDRDTHQRREFVTI 260
Query: 248 TTAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTATGRV 424
G +L VTP H V+V R + + V D + A + P V
Sbjct: 261 EAEGGALLKVTPAHLVMVWRRER-SETRFVFADRVREGDHILVHVAGSLEPRAVHRISAT 319
Query: 425 VAKGLYNPQTLVGSIVVDGFAA 490
+A+G+Y P T G+IVVD AA
Sbjct: 320 LAEGVYAPLTGEGTIVVDSIAA 341
[10][TOP]
>UniRef100_B4LZT9 Protein hedgehog C-product n=1 Tax=Drosophila virilis
RepID=HH_DROVI
Length = 483
Score = 65.1 bits (157), Expect = 3e-09
Identities = 49/140 (35%), Positives = 67/140 (47%), Gaps = 5/140 (3%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CF ++ +E GA K +++LAIGDRV + +G +S+V LF + FV L T
Sbjct: 267 CFTPESTALLESGAKKPLSELAIGDRVLSMNGKGQAVYSEVILFMDRNLEQMQNFVQLHT 326
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTATGRVVA 430
+G VLTVTP H + V + R A V V A P V V +
Sbjct: 327 DSGAVLTVTPAHLITVWQPEREALDFVFADRVEELNYVLVHDATGELRPHRVIRVSSVRS 386
Query: 431 KGLYNPQTLVGSIVVDGFAA 490
+G+ P T G+IVVD AA
Sbjct: 387 RGVVAPLTREGTIVVDSVAA 406
[11][TOP]
>UniRef100_UPI0001555BF7 PREDICTED: similar to Indian hedgehog protein precursor (IHH)
(HHG-2), partial n=1 Tax=Ornithorhynchus anatinus
RepID=UPI0001555BF7
Length = 688
Score = 64.7 bits (156), Expect = 3e-09
Identities = 52/152 (34%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAA--DG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A +E GA ++ L GDRV A DG +FSDV LF P A F+ + T
Sbjct: 463 CFPAGARARLESGALVELSSLRPGDRVLAMGEDGRPTFSDVLLFLDRQPAAARAFLVIET 522
Query: 254 AAGV--LTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAAT---PAVVTATG 418
L +TP H + + TA + S + P A PA V A G
Sbjct: 523 RDPPRRLALTPAHLLFAADN-HTAPAGRFRATFASLVRPGQYVLVAGGPGLQPARVAAVG 581
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
A+G Y P T G++VVD A F E
Sbjct: 582 ARAARGAYAPLTRHGTLVVDDVVASCFAAVAE 613
[12][TOP]
>UniRef100_Q4PLX4 Indian hedgehog n=1 Tax=Danio rerio RepID=Q4PLX4_DANRE
Length = 413
Score = 64.7 bits (156), Expect = 3e-09
Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 15/150 (10%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA---ADGS----FSDVFLFTHADPTAKSTFVT 244
CFPA+A V VE G+ K + L G++V A +DGS +S+V F DP+A+ F T
Sbjct: 198 CFPASALVTVEDGSLKTLDSLQPGEKVLASSESDGSGTLVYSEVIAFLDRDPSARKQFFT 257
Query: 245 LTTAAGV-LTVTPGHYVLVNEG--VRTAASAVVVGDVLSYMPPAGCAAA--AAATPAVVT 409
+ T +G L++T H + V+EG +AA+A + S + P C + AA ++
Sbjct: 258 IETDSGAKLSLTAAHLLFVSEGNCSGSAANAELRSVFASDVLPGQCVVSTQAAGQHGRLS 317
Query: 410 ATGRVVA---KGLYNPQTLVGSIVVDGFAA 490
R+ +G++ P T G++VV+G +
Sbjct: 318 RVSRIQMQEDRGVFAPLTSHGTVVVNGIVS 347
[13][TOP]
>UniRef100_B0S8K0 Indian hedgehog homolog a n=1 Tax=Danio rerio RepID=B0S8K0_DANRE
Length = 413
Score = 64.7 bits (156), Expect = 3e-09
Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 15/150 (10%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA---ADGS----FSDVFLFTHADPTAKSTFVT 244
CFPA+A V VE G+ K + L G++V A +DGS +S+V F DP+A+ F T
Sbjct: 198 CFPASALVTVEDGSLKTLDSLQPGEKVLASSESDGSGTLVYSEVIAFLDRDPSARKQFFT 257
Query: 245 LTTAAGV-LTVTPGHYVLVNEG--VRTAASAVVVGDVLSYMPPAGCAAA--AAATPAVVT 409
+ T +G L++T H + V+EG +AA+A + S + P C + AA ++
Sbjct: 258 IETDSGAKLSLTAAHLLFVSEGNCSGSAANAELRSVFASDVLPGQCVVSTQAAGRHGRLS 317
Query: 410 ATGRVVA---KGLYNPQTLVGSIVVDGFAA 490
R+ +G++ P T G++VV+G +
Sbjct: 318 RVSRIQMQEDRGVFAPLTSHGTVVVNGIVS 347
[14][TOP]
>UniRef100_B4K4M0 Protein hedgehog C-product n=1 Tax=Drosophila mojavensis
RepID=HH_DROMO
Length = 476
Score = 64.7 bits (156), Expect = 3e-09
Identities = 52/153 (33%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = +2
Query: 47 ADESPESTDDDSECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHA 214
+D SP S CF ++ +E GA KA+++LAIGDRV + D +S+V LF
Sbjct: 248 SDSSP-SISHVHGCFTPESTALLESGAEKALSELAIGDRVLSMDTKGQPVYSEVILFMDR 306
Query: 215 DPTAKSTFVTLTTAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAA 391
+ FV L T G VLTVTP H + V + R V V A
Sbjct: 307 NLEQVQNFVQLHTDGGAVLTVTPAHLIAVWQAERQTLEFVFADRVEELSQVLVHDATGEL 366
Query: 392 TPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
P V V ++G+ P T G+IVV+ AA
Sbjct: 367 RPQRVLRVDSVQSRGVVAPLTREGTIVVNSVAA 399
[15][TOP]
>UniRef100_UPI0000F2E04F PREDICTED: similar to Indian hedgehog protein precursor (IHH)
(HHG-2) n=1 Tax=Monodelphis domestica
RepID=UPI0000F2E04F
Length = 599
Score = 64.3 bits (155), Expect = 5e-09
Identities = 53/152 (34%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ L GDRV A DGS FSDV +F +P + F + T
Sbjct: 391 CFPAGARVRLENGARVALSALQPGDRVLAMGEDGSPTFSDVIIFLDREPAIQRVFYVIET 450
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
LT+TP H +L T + S + P A PA V A
Sbjct: 451 LDPPRRLTLTPAH-LLFTANNHTEPATGFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 509
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
A G Y P T G++VV+ A F T E
Sbjct: 510 TQTAPGAYAPLTKHGTLVVEDVVASCFATVAE 541
[16][TOP]
>UniRef100_A3KNS3 Indian hedgehog homolog a n=1 Tax=Danio rerio RepID=A3KNS3_DANRE
Length = 413
Score = 63.5 bits (153), Expect = 8e-09
Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 15/150 (10%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA---ADGS----FSDVFLFTHADPTAKSTFVT 244
CFPA+A V +E G K + L G++V A +DGS +S+V F DP+A+ F T
Sbjct: 198 CFPASALVTIEDGRLKTLESLQPGEKVLASSESDGSGTLVYSEVIAFLDRDPSARKQFFT 257
Query: 245 LTTAAGV-LTVTPGHYVLVNEG--VRTAASAVVVGDVLSYMPPAGCAAA--AAATPAVVT 409
+ T +G L++T H + V+EG +AA+A + S + P C + AA ++
Sbjct: 258 IETDSGAKLSLTAAHLLFVSEGNCSGSAANAELRSVFASDVLPGQCVVSTQAAGQHGRLS 317
Query: 410 ATGRV---VAKGLYNPQTLVGSIVVDGFAA 490
R+ +G++ P T G++VV+G +
Sbjct: 318 RVSRIRMQEDRGVFAPLTSHGTVVVNGIVS 347
[17][TOP]
>UniRef100_P56674 Protein hedgehog C-product n=1 Tax=Drosophila hydei RepID=HH_DROHY
Length = 481
Score = 63.5 bits (153), Expect = 8e-09
Identities = 52/153 (33%), Positives = 71/153 (46%), Gaps = 5/153 (3%)
Frame = +2
Query: 47 ADESPESTDDDSECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHA 214
+D SP S CF ++ +E GA KA+ +LAIGDRV + D +S+V LF
Sbjct: 253 SDSSP-SISHMHGCFTPESTALLESGAEKALGELAIGDRVLSMDVKGQPVYSEVILFMDR 311
Query: 215 DPTAKSTFVTLTTAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAA 391
+ FV L T G VLTVTP H + V + R + + V A
Sbjct: 312 NLEQVENFVQLHTDGGAVLTVTPAHLISVWQPERQTLNFIFADRVEELDYVLVRDATGEL 371
Query: 392 TPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
P V G V ++G+ P T G+IVV+ AA
Sbjct: 372 QPQRVLRLGSVQSRGVVAPLTREGTIVVNSVAA 404
[18][TOP]
>UniRef100_UPI00016E63F0 UPI00016E63F0 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E63F0
Length = 428
Score = 61.2 bits (147), Expect = 4e-08
Identities = 46/147 (31%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + V V GG K+++ L GDRV A + FS V LF H DP ++ F++L T
Sbjct: 205 CFPGWSRVTVAGGFQKSLSSLTPGDRVMALSETGQVVFSPVLLFLHRDPESRWRFLSLQT 264
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGC----AAAAAATPAVVTATG 418
G L VTP H+++ ++ S+ S C A P+ + +
Sbjct: 265 EDGRRLAVTP-HHLVFSDAHCGPDSSQYQAQFASRAQTGTCVLVHTAGGEVHPSRIVSIT 323
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
+ G Y P T GS+ VDG A ++
Sbjct: 324 EEESVGAYAPLTEAGSVFVDGVLASSY 350
[19][TOP]
>UniRef100_UPI00016E63EF UPI00016E63EF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E63EF
Length = 413
Score = 61.2 bits (147), Expect = 4e-08
Identities = 46/147 (31%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + V V GG K+++ L GDRV A + FS V LF H DP ++ F++L T
Sbjct: 199 CFPGWSRVTVAGGFQKSLSSLTPGDRVMALSETGQVVFSPVLLFLHRDPESRWRFLSLQT 258
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGC----AAAAAATPAVVTATG 418
G L VTP H+++ ++ S+ S C A P+ + +
Sbjct: 259 EDGRRLAVTP-HHLVFSDAHCGPDSSQYQAQFASRAQTGTCVLVHTAGGEVHPSRIVSIT 317
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
+ G Y P T GS+ VDG A ++
Sbjct: 318 EEESVGAYAPLTEAGSVFVDGVLASSY 344
[20][TOP]
>UniRef100_UPI000001AC51 UPI000001AC51 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI000001AC51
Length = 442
Score = 61.2 bits (147), Expect = 4e-08
Identities = 46/147 (31%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + V V GG K+++ L GDRV A + FS V LF H DP ++ F++L T
Sbjct: 201 CFPGWSRVTVAGGFQKSLSSLTPGDRVMALSETGQVVFSPVLLFLHRDPESRWRFLSLQT 260
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGC----AAAAAATPAVVTATG 418
G L VTP H+++ ++ S+ S C A P+ + +
Sbjct: 261 EDGRRLAVTP-HHLVFSDAHCGPDSSQYQAQFASRAQTGTCVLVHTAGGEVHPSRIVSIT 319
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
+ G Y P T GS+ VDG A ++
Sbjct: 320 EEESVGAYAPLTEAGSVFVDGVLASSY 346
[21][TOP]
>UniRef100_O73803 Fugu hedgehog n=1 Tax=Takifugu rubripes RepID=O73803_TAKRU
Length = 442
Score = 61.2 bits (147), Expect = 4e-08
Identities = 46/147 (31%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + V V GG K+++ L GDRV A + FS V LF H DP ++ F++L T
Sbjct: 201 CFPGWSRVTVAGGFQKSLSSLTPGDRVMALSETGQVVFSPVLLFLHRDPESRWRFLSLQT 260
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGC----AAAAAATPAVVTATG 418
G L VTP H+++ ++ S+ S C A P+ + +
Sbjct: 261 EDGRRLAVTP-HHLVFSDAHCGPDSSQYQAQFASRAQTGTCVLVHTAGGEVHPSRIVSIT 319
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
+ G Y P T GS+ VDG A ++
Sbjct: 320 EEESVGAYAPLTEAGSVFVDGVLASSY 346
[22][TOP]
>UniRef100_Q1HEQ6 Hedgehog (Fragment) n=1 Tax=Tribolium castaneum RepID=Q1HEQ6_TRICA
Length = 305
Score = 60.8 bits (146), Expect = 5e-08
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 6/146 (4%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-----FSDVFLFTHADPTAKSTFVTLT 250
CF ++V G + ++ L IG++++A D S FS+V LF +P+ K F+ +T
Sbjct: 110 CFSGESTVLTSTGLRRNLSSLQIGEKIQALDPSTNELVFSEVLLFLDYNPSQKRQFLHIT 169
Query: 251 TAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTATGRVV 427
A+G LTVTP H +++++ A + GD L A A + + V
Sbjct: 170 LASGRTLTVTPSHLLVLDDRTMKYAQKLQPGDFLLVSDNAKNALISEK----IVRLEAVW 225
Query: 428 AKGLYNPQTLVGSIVVDGFAAFTFTT 505
G++ P T VG++VV+ A + T
Sbjct: 226 RSGVFAPLTGVGTLVVNDVVASCYAT 251
[23][TOP]
>UniRef100_UPI00016E749E UPI00016E749E related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E749E
Length = 420
Score = 60.5 bits (145), Expect = 7e-08
Identities = 53/156 (33%), Positives = 70/156 (44%), Gaps = 21/156 (13%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-------FSDVFLFTHADPTAKSTFVT 244
CF A V +EGG TK M DL GDRV ++ + +S V F P S F T
Sbjct: 202 CFSGDAQVVLEGGVTKPMRDLRPGDRVLSSSATEGLGPFIYSPVLSFLDRRPNVTSVFYT 261
Query: 245 LTTAAG-VLTVTPGHYVLVNE------------GVRTA-ASAVVVGDVLSYMPPAGCAAA 382
+ T AG +T+T H + V + G+R AS V G + +G
Sbjct: 262 IGTVAGHSITLTAAHLIYVTDYPAQEVGFSRDRGLRIVFASEVQPGQCVL---TSGGKVG 318
Query: 383 AAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+ AT + VT + GLY P T GSIVV+G A
Sbjct: 319 SQATFSPVTFVRAQRSTGLYAPLTEHGSIVVNGVLA 354
[24][TOP]
>UniRef100_A9P334 Hedgehog protein n=1 Tax=Trichinella spiralis RepID=A9P334_TRISP
Length = 445
Score = 60.5 bits (145), Expect = 7e-08
Identities = 46/148 (31%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRV--RAADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CF +++V + K M +L IGDRV R ADG +FS V LF H D K+ F +
Sbjct: 227 CFAGSSTVLTKENGRKRMDELEIGDRVLARKADGKLTFSPVILFLHRDQQTKAKFKAVHI 286
Query: 254 AAG-VLTVTPGHYV-----LVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTAT 415
+ +LT++P H + + N+ + V D+L+ + A V
Sbjct: 287 SNDTLLTISPDHLIYKVDPMTNDNSGGSMETVFAADLLAGDQVFVRNGIFDISRATVLGI 346
Query: 416 GRVVAKGLYNPQTLVGSIVVDGFAAFTF 499
G + +GLY P TL G+I VD A +
Sbjct: 347 GEIERQGLYAPMTLEGNIFVDDVLASNY 374
[25][TOP]
>UniRef100_UPI0000E1F98C PREDICTED: Indian hedgehog homolog n=1 Tax=Pan troglodytes
RepID=UPI0000E1F98C
Length = 411
Score = 59.7 bits (143), Expect = 1e-07
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DGS FSDV +F +P F + T
Sbjct: 203 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSTTFSDVLIFLDREPHRLRVFQVIET 262
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + T +A S++ P A PA V A
Sbjct: 263 QDPPRRLALTPAHLLFTADN-HTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVS 321
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 322 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 353
[26][TOP]
>UniRef100_UPI0000D9D1C5 PREDICTED: Indian hedgehog homolog n=1 Tax=Macaca mulatta
RepID=UPI0000D9D1C5
Length = 526
Score = 59.7 bits (143), Expect = 1e-07
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DGS FSDV +F +P F + T
Sbjct: 318 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRLRAFQVIET 377
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + T +A S++ P A PA V A
Sbjct: 378 QDPPRRLALTPAHLLFTADN-HTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVS 436
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 437 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 468
[27][TOP]
>UniRef100_UPI0000D55873 hedgehog n=1 Tax=Tribolium castaneum RepID=UPI0000D55873
Length = 392
Score = 59.7 bits (143), Expect = 1e-07
Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 6/146 (4%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-----FSDVFLFTHADPTAKSTFVTLT 250
CF ++V G + ++ L IG++++A D S FS+V LF +P+ + F+ +T
Sbjct: 197 CFSGESTVLTSTGLRRNLSSLQIGEKIQALDPSTNELVFSEVLLFLDYNPSQRRQFLHIT 256
Query: 251 TAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTATGRVV 427
A+G LTVTP H +++++ A + GD L A A + + V
Sbjct: 257 LASGRTLTVTPSHLLVLDDRTMKYAQKLQPGDFLLVSDNAKNALISEK----IVRLEAVW 312
Query: 428 AKGLYNPQTLVGSIVVDGFAAFTFTT 505
G++ P T VG++VV+ A + T
Sbjct: 313 RSGVFAPLTGVGTLVVNDVVASCYAT 338
[28][TOP]
>UniRef100_Q175B3 Hedgehog n=1 Tax=Aedes aegypti RepID=Q175B3_AEDAE
Length = 418
Score = 59.7 bits (143), Expect = 1e-07
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 10/147 (6%)
Frame = +2
Query: 80 SECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTL 247
S CF ++V+ G T+ +++L IG++V + D S +S+V +F D FV +
Sbjct: 210 SGCFTGDSTVQTSTGETRKLSELQIGEQVLSVDSSGNTVYSEVIMFMDRDTHQSREFVHI 269
Query: 248 TTAAGV-LTVTPGHYVLV---NEG--VRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
G LTVTP H V+V NEG + A + GD + + P V
Sbjct: 270 EADGGAHLTVTPAHLVMVWQKNEGKSLYLFADRIQEGDYIL------VNINSTIEPRKVL 323
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+++G+Y P T G+IVVD AA
Sbjct: 324 RISAKLSQGVYAPLTREGTIVVDSIAA 350
[29][TOP]
>UniRef100_Q4ZFW8 Putative uncharacterized protein IHH n=1 Tax=Homo sapiens
RepID=Q4ZFW8_HUMAN
Length = 293
Score = 59.7 bits (143), Expect = 1e-07
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DGS FSDV +F +P F + T
Sbjct: 85 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRLRAFQVIET 144
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + T +A S++ P A PA V A
Sbjct: 145 QDPPRRLALTPAHLLFTADN-HTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVS 203
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 204 THVALGAYAPLTKHGTLVVEDVVASCFAAVAD 235
[30][TOP]
>UniRef100_Q14623 Indian hedgehog protein C-product n=2 Tax=Homo sapiens
RepID=IHH_HUMAN
Length = 411
Score = 59.7 bits (143), Expect = 1e-07
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DGS FSDV +F +P F + T
Sbjct: 203 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRLRAFQVIET 262
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + T +A S++ P A PA V A
Sbjct: 263 QDPPRRLALTPAHLLFTADN-HTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVS 321
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 322 THVALGAYAPLTKHGTLVVEDVVASCFAAVAD 353
[31][TOP]
>UniRef100_B4G2I8 Protein hedgehog C-product n=1 Tax=Drosophila persimilis
RepID=HH_DROPE
Length = 481
Score = 59.7 bits (143), Expect = 1e-07
Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 11/146 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CF ++ +E G TK ++++AIGDRV + + +S+V LF + FV L T
Sbjct: 266 CFTPESTALLESGITKPLSEIAIGDRVLSMGSNGQPVYSEVILFMDRNLEQMQNFVELHT 325
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDV--LSYM----PPAGCAAAAAATPAVVTA 412
G VLTVTP H + V R V V L+Y+ P G P V
Sbjct: 326 DGGAVLTVTPAHLISVWHPERQQLDYVFADRVEELNYVLVRDPQTG-----ELRPQRVVR 380
Query: 413 TGRVVAKGLYNPQTLVGSIVVDGFAA 490
G V +KG+ P T G+IVV+ AA
Sbjct: 381 VGSVRSKGVVAPLTREGTIVVNSVAA 406
[32][TOP]
>UniRef100_C9SV27 Pyruvate dehydrogenase protein X component n=1 Tax=Verticillium
albo-atrum VaMs.102 RepID=C9SV27_9PEZI
Length = 496
Score = 59.7 bits (143), Expect = 1e-07
Identities = 51/160 (31%), Positives = 65/160 (40%), Gaps = 2/160 (1%)
Frame = +3
Query: 39 TATLMSRPSPQTMTASASRRRPASRWRAVRPRRWR--TSPSATACGPPTAPSPTCSCSRT 212
T + P P ++ SA+ R P++ RP TSP+ T P +P P S +R+
Sbjct: 270 TQVALPSPWPTSLRPSAASRTPSASSCPSRPSSPAPPTSPTTTCPRPRASPPPPTSSTRS 329
Query: 213 QTRPQSRRL*R*PRRRVCSRSPQATTCWSMKASAPPRRRWWSATSSPTCPPRAAPPPPPP 392
S P C +SP C S +S P R S TSS P AAPP P
Sbjct: 330 SASTPSASPPTPPAASTCRKSPP---CLSPPSSRPAPRAA-SPTSSTCSPAAAAPPAPRS 385
Query: 393 PPQLSRQRVGWSPRGCTTPRRWSAASSSMALLRSPSPPXW 512
PP L R R T P + SS + RS P W
Sbjct: 386 PPSLPPPR----GRASTRPGGTYSPSSCREVTRSAPPSSW 421
[33][TOP]
>UniRef100_UPI00015B6385 PREDICTED: similar to hedgehog n=1 Tax=Nasonia vitripennis
RepID=UPI00015B6385
Length = 447
Score = 59.3 bits (142), Expect = 1e-07
Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-----FSDVFLFTHADPTAKSTFVTLT 250
CFP + V G T+ + +L +GDRV A D S +S+V F P + F+ L+
Sbjct: 215 CFPGASLVRTSDGLTRRLDELRLGDRVAAMDHSTGEIVYSEVLAFIDRQPEERRQFIRLS 274
Query: 251 TAAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAV-----VTA 412
T +G VLT+TP H V + A+ V GD L + A V
Sbjct: 275 TKSGQVLTLTPQHLVPIEGKSAVFAARVQPGDRLLVRHVVTSSLELEANNETLRYDEVLE 334
Query: 413 TGRVVAKGLYNPQTLVGSIVVDGFAA 490
V+ +G+Y P T G+++V+ A
Sbjct: 335 AKLVLEEGVYAPLTAQGTLLVNDVVA 360
[34][TOP]
>UniRef100_Q91611 Desert hedgehog protein 2 C-product n=1 Tax=Xenopus laevis
RepID=DHH2_XENLA
Length = 398
Score = 59.3 bits (142), Expect = 1e-07
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 13/153 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP TA V +E G K +++L +GD V D + S V LF H DP +TFV L
Sbjct: 200 CFPGTAMVMMETGKKKPLSELKLGDTVFTTDETGLLIHSVVLLFLHRDPYKTATFV-LIE 258
Query: 254 AAG---VLTVTPGHYVLVNEGVRTA-----ASAVVVGDVLS-YMPPAGCAAAAAATPAVV 406
A G L VTP H + + T A V +GD++ Y+ ++ +V
Sbjct: 259 AEGHPTKLLVTPNHLLFIKSSSSTGFQPTFAYRVQIGDLIQIYVNGTQVQSSKVVRVSVD 318
Query: 407 TATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTT 505
T G+Y P T G+++VDG + T
Sbjct: 319 EQT------GVYAPMTEHGTLLVDGVLTSCYAT 345
[35][TOP]
>UniRef100_C5WZY8 Putative uncharacterized protein Sb01g048565 (Fragment) n=1
Tax=Sorghum bicolor RepID=C5WZY8_SORBI
Length = 201
Score = 58.9 bits (141), Expect = 2e-07
Identities = 56/165 (33%), Positives = 70/165 (42%), Gaps = 4/165 (2%)
Frame = +3
Query: 24 GRVTVTATLMSRPSPQTMTASA-SRRRPASRWRAVRPRRWRTSPSATACGPPTAPSPTCS 200
G++ + R P + TASA + RRPA+ W R W S TA G +
Sbjct: 6 GQIRASGQSSRRGCPASGTASARTSRRPATPWSC--RRTW--SRRRTASG---------A 52
Query: 201 CSRTQTRPQSRRL*R*PRRRVCSRSPQATTCWSMKASAPPRRRWWSATSSPTCPPRAAPP 380
C R +RR R R + TT WS A +P RW + + P C P +
Sbjct: 53 CKWWTGRRSARRW------RTRQRRARCTTAWS--ACSP---RWGARPTPPPCTPPTSAT 101
Query: 381 PPPPPPQLSRQRVGWSPRGCTTPR---RWSAASSSMALLRSPSPP 506
PPPP P + R SPRG PR RWS A S A R P P
Sbjct: 102 PPPPLPSRTPPRGPTSPRGPGAPRPCSRWSTA--SCARTRPPRRP 144
[36][TOP]
>UniRef100_UPI00005A5AA2 PREDICTED: similar to Indian hedgehog protein precursor (IHH)
(HHG-2) n=1 Tax=Canis lupus familiaris
RepID=UPI00005A5AA2
Length = 373
Score = 58.5 bits (140), Expect = 2e-07
Identities = 50/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 165 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRMRAFQVIET 224
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L T +A S + P A PA V A
Sbjct: 225 QDPPRRLALTPAH-LLFTSNNHTEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 283
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 284 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 315
[37][TOP]
>UniRef100_UPI0000EB02AD Indian hedgehog protein precursor (IHH) (HHG-2) [Contains: Indian
hedgehog protein N-product; Indian hedgehog protein
C-product]. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB02AD
Length = 353
Score = 58.5 bits (140), Expect = 2e-07
Identities = 50/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 159 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRMRAFQVIET 218
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L T +A S + P A PA V A
Sbjct: 219 QDPPRRLALTPAH-LLFTSNNHTEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 277
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 278 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 309
[38][TOP]
>UniRef100_Q4THG0 Chromosome undetermined SCAF2971, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4THG0_TETNG
Length = 273
Score = 58.5 bits (140), Expect = 2e-07
Identities = 48/117 (41%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA-ADGS---FSDVFLFTHADPTAKSTFVTLTT 253
CFP ASV +EGG TKA+ DL G+RV A AD +S V F DP A F TL T
Sbjct: 12 CFPGEASVALEGGGTKAVRDLQPGERVLALADAGELVYSQVLAFLDHDPGAWKLFYTLHT 71
Query: 254 AAGV-LTVTPGHYVLVNEG------VRTAASAVVVGDVLSYMPPAGCAAAAAATPAV 403
AG L +T H + V EG R A + + V S A A A PAV
Sbjct: 72 RAGPRLALTAAHLLFVAEGNCSEGAERPPAPSRLCTPVASGRASACWCPGALARPAV 128
[39][TOP]
>UniRef100_Q29AA9 Protein hedgehog C-product n=1 Tax=Drosophila pseudoobscura
pseudoobscura RepID=HH_DROPS
Length = 481
Score = 58.5 bits (140), Expect = 2e-07
Identities = 49/146 (33%), Positives = 69/146 (47%), Gaps = 11/146 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CF ++ +E G TK +++++IGDRV + + +S+V LF + FV L T
Sbjct: 266 CFTPESTALLESGITKPLSEISIGDRVLSMGSNGQPVYSEVILFMDRNLEQMQNFVELHT 325
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDV--LSYM----PPAGCAAAAAATPAVVTA 412
G VLTVTP H + V R V V L+Y+ P G P V
Sbjct: 326 DGGAVLTVTPAHLISVWHPERQQLDYVFADRVEELNYVLVRDPQTG-----ELRPQRVVR 380
Query: 413 TGRVVAKGLYNPQTLVGSIVVDGFAA 490
G V +KG+ P T G+IVV+ AA
Sbjct: 381 VGSVRSKGVVAPLTREGTIVVNSVAA 406
[40][TOP]
>UniRef100_Q7Z264 Hedgehog (Fragment) n=1 Tax=Euscorpius flavicaudis
RepID=Q7Z264_9SCOR
Length = 381
Score = 58.2 bits (139), Expect = 3e-07
Identities = 46/141 (32%), Positives = 67/141 (47%), Gaps = 6/141 (4%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRV----RAADGSFSDVFLFTHADPTAKSTFVTLTT 253
CF + V + GA K M++L +G+ V R ++S V +F DP F L T
Sbjct: 169 CFQGNSVVLTKNGAKK-MSELDVGNEVLDCSRNGFFTYSQVIMFLDWDPKTNRQFYVLHT 227
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVL-SYMPPAGCAAAAAATPAVVTATGRVV 427
G +T+TP H + V G +T V DV + A +P +VT +V
Sbjct: 228 NTGRSITLTPSHLIFVVGGNKTRV--VFTRDVRPGHYILAKHFRENVTSPELVTHVTTIV 285
Query: 428 AKGLYNPQTLVGSIVVDGFAA 490
G+Y P T+ G++VVDGF A
Sbjct: 286 TTGVYAPLTIQGNLVVDGFVA 306
[41][TOP]
>UniRef100_UPI000162ECA3 Indian hedgehog homolog n=1 Tax=Bos taurus RepID=UPI000162ECA3
Length = 309
Score = 57.8 bits (138), Expect = 4e-07
Identities = 50/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 101 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRLRAFQVIET 160
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L T +A S + P A PA V A
Sbjct: 161 QDPPRRLALTPAH-LLFTANNHTEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 219
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 220 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 251
[42][TOP]
>UniRef100_UPI0001951403 UPI0001951403 related cluster n=1 Tax=Bos taurus
RepID=UPI0001951403
Length = 412
Score = 57.8 bits (138), Expect = 4e-07
Identities = 50/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 204 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRLRAFQVIET 263
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L T +A S + P A PA V A
Sbjct: 264 QDPPRRLALTPAH-LLFTANNHTEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 322
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 323 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 354
[43][TOP]
>UniRef100_Q08D77 Indian hedgehog homolog (Drosophila) n=1 Tax=Bos taurus
RepID=Q08D77_BOVIN
Length = 225
Score = 57.8 bits (138), Expect = 4e-07
Identities = 50/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 17 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRLRAFQVIET 76
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L T +A S + P A PA V A
Sbjct: 77 QDPPRRLALTPAH-LLFTANNHTEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 135
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 136 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 167
[44][TOP]
>UniRef100_UPI0001A2DF04 Sonic hedgehog A protein precursor (SHHA) (VHH-1) [Contains: Sonic
hedgehog A protein N-product; Sonic hedgehog A protein
C-product]. n=1 Tax=Danio rerio RepID=UPI0001A2DF04
Length = 416
Score = 57.4 bits (137), Expect = 6e-07
Identities = 47/149 (31%), Positives = 68/149 (45%), Gaps = 14/149 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP +A V ++ G KA+ DL GD+V AAD + FSD +FT D T + F + T
Sbjct: 198 CFPGSALVSLQDGGQKAVKDLNPGDKVLAADSAGNLVFSDFIMFTDRDSTTRRVFYVIET 257
Query: 254 AAGV--LTVTPGHYVLV----NEGVRTA----ASAVVVGDVLSYMPPAGCAAAAAATPAV 403
V +T+T H + V E + T AS+V G + + +G +
Sbjct: 258 QEPVEKITLTAAHLLFVLDNSTEDLHTMTAAYASSVRAGQKVMVVDDSG-----QLKSVI 312
Query: 404 VTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
V +G + P T G+IVVD A
Sbjct: 313 VQRIYTEEQRGSFAPVTAHGTIVVDRILA 341
[45][TOP]
>UniRef100_B6CGL3 Hint2 (Fragment) n=1 Tax=Nematostella vectensis RepID=B6CGL3_NEMVE
Length = 461
Score = 57.4 bits (137), Expect = 6e-07
Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 10/153 (6%)
Frame = +2
Query: 62 ESTDDDSECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAK 229
++ + CFP VE+E G + DL IGDR++ S +SDV F H + T
Sbjct: 271 QTIETGKRCFPGNGKVELESGVQMYIRDLRIGDRIKTVGSSGDVIYSDVIAFLHKNTTIV 330
Query: 230 STFVTL-TTAAGVLTVTPGHYVLVNEGVRTAASAVV-----VGDVLSYMPPAGCAAAAAA 391
FV L T + ++ H + V++ + + A+ V D + +
Sbjct: 331 VEFVALHLTGEHRIIISAKHLIFVSKNGNSTSEAIFADRVHVDDTVYVLEGGKLVVKKVV 390
Query: 392 TPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
A+VT + G+Y P T G++VV+G A
Sbjct: 391 RVAMVTES------GIYAPLTREGTLVVNGVFA 417
[46][TOP]
>UniRef100_Q92008 Sonic hedgehog protein A C-product n=2 Tax=Danio rerio
RepID=SHH_DANRE
Length = 418
Score = 57.4 bits (137), Expect = 6e-07
Identities = 47/149 (31%), Positives = 68/149 (45%), Gaps = 14/149 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP +A V ++ G KA+ DL GD+V AAD + FSD +FT D T + F + T
Sbjct: 198 CFPGSALVSLQDGGQKAVKDLNPGDKVLAADSAGNLVFSDFIMFTDRDSTTRRVFYVIET 257
Query: 254 AAGV--LTVTPGHYVLV----NEGVRTA----ASAVVVGDVLSYMPPAGCAAAAAATPAV 403
V +T+T H + V E + T AS+V G + + +G +
Sbjct: 258 QEPVEKITLTAAHLLFVLDNSTEDLHTMTAAYASSVRAGQKVMVVDDSG-----QLKSVI 312
Query: 404 VTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
V +G + P T G+IVVD A
Sbjct: 313 VQRIYTEEQRGSFAPVTAHGTIVVDRILA 341
[47][TOP]
>UniRef100_P97812 Indian hedgehog protein C-product n=2 Tax=Mus musculus
RepID=IHH_MOUSE
Length = 411
Score = 57.0 bits (136), Expect = 7e-07
Identities = 47/152 (30%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E G A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 203 CFPAGAQVRLENGERVALSAVKPGDRVLAMGEDGTPTFSDVLIFLDREPNRLRAFQVIET 262
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + + T +A S++ P + PA V A
Sbjct: 263 QDPPRRLALTPAHLLFIADN-HTEPAAHFRATFASHVQPGQYVLVSGVPGLQPARVAAVS 321
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 322 THVALGSYAPLTRHGTLVVEDVVASCFAAVAD 353
[48][TOP]
>UniRef100_A8IY37 Sonic hedgehog n=1 Tax=Suncus murinus RepID=A8IY37_SUNMU
Length = 431
Score = 57.0 bits (136), Expect = 7e-07
Identities = 52/158 (32%), Positives = 65/158 (41%), Gaps = 15/158 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFV---- 241
CFP A+V +E G TK + DL GDRV AAD +SD F D A F
Sbjct: 199 CFPGWATVRLEQGGTKRVRDLRPGDRVLAADEQGRLLYSDFLAFLDRDDGATKLFYEIET 258
Query: 242 ------TLTTAAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAV 403
L TAA +L V P + + AS+V G + G A PA
Sbjct: 259 REPRERLLLTAAHLLFVAPPNGTARTPAGASFASSVRPGQRVYVAAERG--GAPRLLPAT 316
Query: 404 VTATG-RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
V G R A G Y P T G+I++D A + E
Sbjct: 317 VHRVGLREEAAGAYAPLTAQGTILIDRVLASCYAVIAE 354
[49][TOP]
>UniRef100_UPI0000ECA1BA Serine/arginine repetitive matrix protein 1. n=1 Tax=Gallus gallus
RepID=UPI0000ECA1BA
Length = 643
Score = 57.0 bits (136), Expect = 7e-07
Identities = 58/174 (33%), Positives = 74/174 (42%), Gaps = 25/174 (14%)
Frame = +3
Query: 60 PSPQTMTASASRRRPASRWRAVRPRRWRTSPSATACGPPTAPSPTCSCSRTQTRPQSRRL 239
P+PQ ++ P R + PRR R SPS +PSP P+ RR
Sbjct: 357 PTPQQSNRASPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSP-------PPPPRRRRS 409
Query: 240 *R*PRRRVCSR----SPQATTCWSMKASAPPRRRWWSATS---------SPTCPPR---A 371
PRRR C+ T+ + S PPRRR S SP+ PP+ A
Sbjct: 410 PSLPRRRYCALILVIFGLLTSSCDLSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 469
Query: 372 APPPPP-----PPPQLSRQRVGWSP----RGCTTPRRWSAASSSMALLRSPSPP 506
+PPPPP P PQ S++RV SP R +R S + SS R SPP
Sbjct: 470 SPPPPPKRRASPSPQ-SKRRVSHSPPPKQRSSPAAKRRSPSISSKH--RKGSPP 520
[50][TOP]
>UniRef100_C1MUJ6 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MUJ6_9CHLO
Length = 300
Score = 57.0 bits (136), Expect = 7e-07
Identities = 56/170 (32%), Positives = 78/170 (45%), Gaps = 13/170 (7%)
Frame = +3
Query: 27 RVTVTATLMS-RPSPQTMTASASRRRPASRWRAVRPRRWRTSPSATACGPPTA------- 182
R +VTA S R + + TA S RR + R A+ R R +P G PTA
Sbjct: 124 RESVTAARRSSRTASRAATAPPSPRRRSRRRSALSSRGTRAAPRRR--GSPTARPRRRRR 181
Query: 183 ----PSPTC-SCSRTQTRPQSRRL*R*PRRRVCSRSPQATTCWSMKASAPPRRRWWSATS 347
PSP + +R ++ P++ R+ R RRR RS +++ ++ SAP R S
Sbjct: 182 RPRRPSPVVWTRARARSNPRTCRVRRRRRRRRSRRSRRSS---ALTRSAPASSR--SPPP 236
Query: 348 SPTCPPRAAPPPPPPPPQLSRQRVGWSPRGCTTPRRWSAASSSMALLRSP 497
PPR APPPPPPPP PRR A+ ++ + RSP
Sbjct: 237 RTRRPPRVAPPPPPPPP---------------PPRRPPVATGAIPVPRSP 271
[51][TOP]
>UniRef100_UPI0000250E2F Indian hedgehog protein n=2 Tax=Rattus norvegicus
RepID=UPI0000250E2F
Length = 449
Score = 56.6 bits (135), Expect = 9e-07
Identities = 48/147 (32%), Positives = 66/147 (44%), Gaps = 9/147 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E G A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 241 CFPAGAQVHLETGERVALSAVKPGDRVLAMGEDGNPTFSDVLIFLDREPNRLRAFQVIET 300
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H + + + T +A S++ P A PA V A
Sbjct: 301 QDPPRRLALTPAHLLFIADN-HTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAIS 359
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTF 499
VA G Y P T G++VV+ A F
Sbjct: 360 THVALGSYAPLTRHGTLVVEDVVASCF 386
[52][TOP]
>UniRef100_A7RW45 Hedgehog2 (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7RW45_NEMVE
Length = 376
Score = 56.6 bits (135), Expect = 9e-07
Identities = 44/155 (28%), Positives = 72/155 (46%), Gaps = 10/155 (6%)
Frame = +2
Query: 44 DADESPESTDDDSECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTH 211
D D+ E+T CFPA ++ + G M DL +GD+V + D +S V +F H
Sbjct: 166 DEDDYRENTG----CFPAASTARLATGEQVPMVDLRLGDKVASVDDRGGIIYSPVIMFLH 221
Query: 212 ADPTAKSTFVTLTTAAGV-LTVTPGH--YVLVNEGVRTA---ASAVVVGDVLSYMPPAGC 373
P F+ + T L +T H Y + + R A V VGD++ G
Sbjct: 222 RSPELIMDFLKIRTENQTELVITASHLIYKINRQSKRKEACFAKDVTVGDLVFV---GGR 278
Query: 374 AAAAAATPAVVTATGRVVAKGLYNPQTLVGSIVVD 478
++ + +P VT+ R ++G++ P T G++ VD
Sbjct: 279 SSTKSLSPGRVTSVERTRSRGVFAPLTQAGNLFVD 313
[53][TOP]
>UniRef100_A7RN29 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7RN29_NEMVE
Length = 143
Score = 56.6 bits (135), Expect = 9e-07
Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 10/145 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTL-T 250
CFP VE+E G + DL IGDR++ S +SDV F H + T FV L
Sbjct: 1 CFPGNGKVELESGVQMYIRDLRIGDRIKTVGSSGDVIYSDVIAFLHKNTTIVVEFVALHL 60
Query: 251 TAAGVLTVTPGHYVLVNEGVRTAASAVV-----VGDVLSYMPPAGCAAAAAATPAVVTAT 415
T + ++ H + V++ + + A+ V D + + A+VT +
Sbjct: 61 TGEHRIIISAKHLIFVSKNGNSTSEAIFADRVHVDDTVYVLEGGKLVVKKVVRVAMVTES 120
Query: 416 GRVVAKGLYNPQTLVGSIVVDGFAA 490
G+Y P T G++VV+G A
Sbjct: 121 ------GIYAPLTREGTLVVNGVFA 139
[54][TOP]
>UniRef100_UPI00017961FA PREDICTED: Indian hedgehog n=1 Tax=Equus caballus
RepID=UPI00017961FA
Length = 343
Score = 56.2 bits (134), Expect = 1e-06
Identities = 49/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 135 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRLRAFQVIET 194
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L + +A S + P A PA V A
Sbjct: 195 QDPPRRLALTPAH-LLFTANNHSEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 253
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 254 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 285
[55][TOP]
>UniRef100_UPI00016E749F UPI00016E749F related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E749F
Length = 430
Score = 56.2 bits (134), Expect = 1e-06
Identities = 51/165 (30%), Positives = 67/165 (40%), Gaps = 30/165 (18%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-------FSDVFLFTHADPTAKSTFVT 244
CF A V +EGG TK M DL GDRV ++ + +S V F P S F T
Sbjct: 200 CFSGDAQVVLEGGVTKPMRDLRPGDRVLSSSATEGLGPFIYSPVLSFLDRRPNVTSVFYT 259
Query: 245 LTTAAG-VLTVTPGHYVLVNEGVRTAASAVVVGD----------------VLSYMPPAGC 373
+ T AG +T+T H + V + V + D S + P C
Sbjct: 260 IGTVAGHSITLTAAHLIYVTDCVWNETYGDLYLDPAQEVGFSRDRGLRIVFASEVQPGQC 319
Query: 374 A------AAAAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+ AT + VT + GLY P T GSIVV+G A
Sbjct: 320 VLTSGGKVGSQATFSPVTFVRAQRSTGLYAPLTEHGSIVVNGVLA 364
[56][TOP]
>UniRef100_Q6DBX7 Sonic hedgehog b n=1 Tax=Danio rerio RepID=Q6DBX7_DANRE
Length = 416
Score = 56.2 bits (134), Expect = 1e-06
Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 12/143 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + +V + G K + DL +GDRV AAD SD +F DPT + F+ + T
Sbjct: 201 CFPGSGTVTLGDGTRKPIKDLKVGDRVLAADEKGNVLISDFIMFIDHDPTTRRQFIVIET 260
Query: 254 AAGV--LTVTPGHYVLVNEG------VRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+ LT+T H V V T AS V GD + + + + T
Sbjct: 261 SEPFTKLTLTAAHLVFVGNSSAASGITATFASNVKPGDTVLVWEDTCESLKSVTVKRIYT 320
Query: 410 ATGRVVAKGLYNPQTLVGSIVVD 478
+G + P T G+I+VD
Sbjct: 321 EE----HEGSFAPVTAHGTIIVD 339
[57][TOP]
>UniRef100_Q4RQR6 Chromosome 2 SCAF15004, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RQR6_TETNG
Length = 415
Score = 56.2 bits (134), Expect = 1e-06
Identities = 52/163 (31%), Positives = 68/163 (41%), Gaps = 28/163 (17%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS-----FSDVFLFTHADPTAKSTFVTLT 250
CF V +EG TK M DL GDRV A+ G +S V F P A S F T+
Sbjct: 202 CFHGDTQVILEGSVTKPMRDLRPGDRVLASSGGGGPLVYSSVLSFLDRQPNATSVFYTIG 261
Query: 251 TAAG-VLTVTPGHYVLVN----------------EGVRTAASAVVVGDVLSYMPPAGCAA 379
T AG +T+T H + V +G R++ + S + P C
Sbjct: 262 TDAGHRITLTAAHLIYVTDCAWSGTHGEPYLDSVQGGRSSRDRGLRIVFASEVRPGQCVL 321
Query: 380 AAA------ATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+ AT + VT + GLY P T GSIVV+G A
Sbjct: 322 TSGGKLGSPATFSPVTFVHVRRSTGLYAPLTEHGSIVVNGVLA 364
[58][TOP]
>UniRef100_B1H1W3 LOC398047 protein (Fragment) n=1 Tax=Xenopus laevis
RepID=B1H1W3_XENLA
Length = 340
Score = 56.2 bits (134), Expect = 1e-06
Identities = 46/155 (29%), Positives = 66/155 (42%), Gaps = 12/155 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V VE G TKA+ DL GDRV ++D +SD +F + K F + T
Sbjct: 95 CFPAGARVMVEFGGTKAVKDLRPGDRVLSSDPQGNLLYSDFLMFIDQERDVKKLFYVIET 154
Query: 254 AAGVLTVTPGHYVLVNE----GVRT----AASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+ + +T H + V + G R+ AS + GD++ P A V
Sbjct: 155 SQRKIRLTAAHLLFVAQTKVNGTRSFKSVFASNIQPGDLIYTADPKTMTLKAVKVEKVDL 214
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
G Y P T G++V+D A + E
Sbjct: 215 EED----TGAYAPLTAHGTVVIDQVLASCYAVIEE 245
[59][TOP]
>UniRef100_Q8MIN9 Indian hedgehog (Fragment) n=1 Tax=Equus caballus
RepID=Q8MIN9_HORSE
Length = 202
Score = 56.2 bits (134), Expect = 1e-06
Identities = 49/152 (32%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRA--ADG--SFSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V +E GA A++ + GDRV A DG +FSDV +F +P F + T
Sbjct: 44 CFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGNPTFSDVLIFLDREPDRLRAFQVIET 103
Query: 254 --AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG---CAAAAAATPAVVTATG 418
L +TP H +L + +A S + P A PA V A
Sbjct: 104 QDPPRRLALTPAH-LLFTANNHSEPAAHFRATFASQVQPGQYVLVAGVPGLQPARVAAVS 162
Query: 419 RVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
VA G Y P T G++VV+ A F +
Sbjct: 163 THVALGAYAPLTRHGTLVVEDVVASCFAAVAD 194
[60][TOP]
>UniRef100_Q1PHR2 Hedgehog (Fragment) n=1 Tax=Saccoglossus kowalevskii
RepID=Q1PHR2_SACKO
Length = 397
Score = 56.2 bits (134), Expect = 1e-06
Identities = 46/147 (31%), Positives = 69/147 (46%), Gaps = 12/147 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAA--DGS--FSDVFLFTHADPTAKSTFVTLTT 253
CFP A+V +E G TK++ L IG++V A DG+ +SDV + + P + F + T
Sbjct: 182 CFPGDATVTLENGLTKSLDQLTIGEKVMAVNEDGTIVYSDVIMMMDSKPNRRQRFHVIET 241
Query: 254 AAG-VLTVTPGHYVLVNEGVRT----AASAVVVGDV-LSY--MPPAGCAAAAAATPAVVT 409
G LT+TP H V + T + S V DV L + ++ PA V
Sbjct: 242 EDGQKLTLTPQHLVYASRSNVTFDPGSVSPVYAADVELGHYVYTSHDRGRYSSIKPAKVI 301
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
V G+Y P T G+I+++ A
Sbjct: 302 TISSVENVGVYAPLTREGTIIINNIVA 328
[61][TOP]
>UniRef100_Q90419 Tiggy-winkle hedgehog protein C-product n=2 Tax=Danio rerio
RepID=TWHH_DANRE
Length = 416
Score = 56.2 bits (134), Expect = 1e-06
Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 12/143 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + +V + G K + DL +GDRV AAD SD +F DPT + F+ + T
Sbjct: 201 CFPGSGTVTLGDGTRKPIKDLKVGDRVLAADEKGNVLISDFIMFIDHDPTTRRQFIVIET 260
Query: 254 AAGV--LTVTPGHYVLVNEG------VRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+ LT+T H V V T AS V GD + + + + T
Sbjct: 261 SEPFTKLTLTAAHLVFVGNSSAASGITATFASNVKPGDTVLVWEDTCESLKSVTVKRIYT 320
Query: 410 ATGRVVAKGLYNPQTLVGSIVVD 478
+G + P T G+I+VD
Sbjct: 321 EE----HEGSFAPVTAHGTIIVD 339
[62][TOP]
>UniRef100_Q92000 Sonic hedgehog protein C-product n=1 Tax=Xenopus laevis
RepID=SHH_XENLA
Length = 444
Score = 56.2 bits (134), Expect = 1e-06
Identities = 46/155 (29%), Positives = 66/155 (42%), Gaps = 12/155 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFPA A V VE G TKA+ DL GDRV ++D +SD +F + K F + T
Sbjct: 199 CFPAGARVMVEFGGTKAVKDLRPGDRVLSSDPQGNLLYSDFLMFIDQERDVKKLFYVIET 258
Query: 254 AAGVLTVTPGHYVLVNE----GVRT----AASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+ + +T H + V + G R+ AS + GD++ P A V
Sbjct: 259 SQRKIRLTAAHLLFVAQTKVNGTRSFKSVFASNIQPGDLIYTADPKTMTLKAVKVEKVDL 318
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
G Y P T G++V+D A + E
Sbjct: 319 EED----TGAYAPLTAHGTVVIDQVLASCYAVIEE 349
[63][TOP]
>UniRef100_Q69L88 cDNA clone:J013069I08, full insert sequence n=1 Tax=Oryza sativa
Japonica Group RepID=Q69L88_ORYSJ
Length = 808
Score = 56.2 bits (134), Expect = 1e-06
Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 3/172 (1%)
Frame = +3
Query: 6 ATVPVTGRVTVTATLMSRPSPQTMTASASRRRPASRWRAVRPRRWRTSPSATACGPPTAP 185
+T P + + T T S SP + TAS+S SPS++ P+AP
Sbjct: 34 STPPPSTAASATPTTSSASSPSSSTASSS------------------SPSSSTSTSPSAP 75
Query: 186 SPTCSCSRTQTRPQSRRL*R*PRRRVCSRSPQATTCWSMKASAPPRRRWWSATSSPTCPP 365
+ T + + + + P S R AS+P R S+TS+ PP
Sbjct: 76 TTTETAALSPSTPSSPATPR-------------------SASSPTSRPRTSSTSTSASPP 116
Query: 366 RAAPPP---PPPPPQLSRQRVGWSPRGCTTPRRWSAASSSMALLRSPSPPXW 512
R+A PP PPPP+ +P G T R +A S+S + SPP W
Sbjct: 117 RSAAPPSSASPPPPRS-------APSGSRTSSRTAAPSASPSSSSPSSPPPW 161
[64][TOP]
>UniRef100_UPI0001925B52 PREDICTED: similar to hedgehog n=1 Tax=Hydra magnipapillata
RepID=UPI0001925B52
Length = 866
Score = 55.8 bits (133), Expect = 2e-06
Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 10/152 (6%)
Frame = +2
Query: 53 ESPESTDDDSECFPATASVEVEG-GATKAMADLAIGDRVRAADGS-----FSDVFLFTHA 214
E + DD +CFP A V V+G + + L + D + D + +S V++F H
Sbjct: 646 EGEIAKSDDPKCFPEKALVYVKGHNSPITLNKLKVRDEALSFDTNSQQLVYSPVYMFGHK 705
Query: 215 DPTAKSTFVTLTTAAGVLTVTPGHYVLVNEGVRTA----ASAVVVGDVLSYMPPAGCAAA 382
D + +TF+ + T+ G ++++ E + A V+VGD L +
Sbjct: 706 DGSIITTFIYIQTSNGFSVTLSAKHMIMVENISNIDVKFADQVLVGDTLLQIETKDNKMI 765
Query: 383 AAATPAVVTATGRVVAKGLYNPQTLVGSIVVD 478
VT V++KG+Y+P T G+I+VD
Sbjct: 766 IVKEK--VTKISNVISKGIYSPFTKTGTIIVD 795
[65][TOP]
>UniRef100_UPI0000DB7FEB PREDICTED: similar to sonic hedgehog, partial n=1 Tax=Apis
mellifera RepID=UPI0000DB7FEB
Length = 225
Score = 55.8 bits (133), Expect = 2e-06
Identities = 39/141 (27%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP + V G+ K + + +GDR+ A D + +S+V F T + FV LTT
Sbjct: 10 CFPGKSLVRTSDGSMKRLDQVQLGDRIAALDSNGDIVYSEVIAFLDRSLTERRQFVRLTT 69
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG-CAAAAAATPAVVTATGRVV 427
+G +LT+TP H V V A + +GD + + V V+
Sbjct: 70 ESGHILTLTPAHLVPVEGRSTVFAGRIRLGDKILVRDSSNEIEVQHRLRWDKVIDNQLVL 129
Query: 428 AKGLYNPQTLVGSIVVDGFAA 490
+G++ P T G++++D A
Sbjct: 130 EEGIFAPLTTEGTVLIDDVVA 150
[66][TOP]
>UniRef100_Q75UQ8 Hedgehog n=1 Tax=Parasteatoda tepidariorum RepID=Q75UQ8_PARTP
Length = 404
Score = 55.8 bits (133), Expect = 2e-06
Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 10/145 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAA--DGS--FSDVFLFTHADPTAKSTFVTLTT 253
CF ++V E G K M+DL +G+RV+ A DG +S+V LF + T + + TL T
Sbjct: 196 CFDGDSTVRTEAGPKK-MSDLQVGERVQVARTDGQTDYSEVILFLDRNETQQRLYNTLET 254
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASA-----VVVGDVLSYMPPAGCAAAAAATPAVVTAT 415
G +T+TP H + +T A V +GD + A+ T V +
Sbjct: 255 ENGRSITLTPTHLIFTASPHQTTPQATFAKHVEIGDYIYV------ASDRKVTLEKVISV 308
Query: 416 GRVVAKGLYNPQTLVGSIVVDGFAA 490
KG++ P T G++VVDG A
Sbjct: 309 TSSAKKGVFAPLTREGNLVVDGVVA 333
[67][TOP]
>UniRef100_UPI0001791CD5 PREDICTED: similar to AGAP001412-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001791CD5
Length = 437
Score = 55.5 bits (132), Expect = 2e-06
Identities = 53/149 (35%), Positives = 67/149 (44%), Gaps = 14/149 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAA--DGSF--SDVFLFTHADPTAKSTFVTLTT 253
CFP + V G K M DL +G+ V A DG S+V LF + TA + +VTL T
Sbjct: 208 CFPGDSVVTTGAGVKKQMKDLRVGESVLALSNDGLLRPSEVLLFLDRNVTALTEYVTLVT 267
Query: 254 AAGV-LTVTPGHYVLVNEG-----VRTA----ASAVVVGDVLSYMPPAGCAAAAAATPAV 403
G +T TP H VL E +R A A +V V D L + V
Sbjct: 268 DTGKSITATPTHLVLRWEKPERSQIRYANPVYAKSVRVNDTLLTVINGDRGQLRLRAERV 327
Query: 404 VTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
V A R GLY P T+ G++VVD A
Sbjct: 328 V-AVSRTEKIGLYAPLTVDGTVVVDDVVA 355
[68][TOP]
>UniRef100_A4UYK7 Sonic hedgehog protein n=1 Tax=Polypterus bichir RepID=A4UYK7_9ACTI
Length = 420
Score = 55.5 bits (132), Expect = 2e-06
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG----SFSDVFLFTHADPTAKSTFVTLTT 253
CFP +ASV ++ G K + DLA GD+V AA+ FSD +F+ D + F + T
Sbjct: 198 CFPGSASVALKDGPQKTVKDLARGDKVLAAESLGKRRFSDFIMFSDQDSATRRVFYVIET 257
Query: 254 AAGV--LTVTPGHYVLVNEG--------VRTAASAVVVGDVLSYMPPAGCAAAAAATPAV 403
V +T+T H + V + AS+V G + G A +
Sbjct: 258 KEPVEKITLTAAHLLFVLDNSTDVVSTMTAAFASSVRAGQKVMVSDHRG---AQLLQSVI 314
Query: 404 VTATGRVVAKGLYNPQTLVGSIVVD 478
V A G Y P T G+IVVD
Sbjct: 315 VERIYTEEASGAYAPVTAHGTIVVD 339
[69][TOP]
>UniRef100_A0JM37 Dhh protein n=1 Tax=Xenopus (Silurana) tropicalis
RepID=A0JM37_XENTR
Length = 396
Score = 55.5 bits (132), Expect = 2e-06
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 11/151 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGSF----SDVFLFTHADPTAKSTFVTLTT 253
CFP TA V + G K++++L +GD V D + S V LF H D +TFV +
Sbjct: 198 CFPGTAMVMMASGEKKSLSELQLGDTVFTTDETGQLIPSVVLLFLHRDLYKTATFVLIEA 257
Query: 254 A--AGVLTVTPGHYVLVNEGVR-----TAASAVVVGDVLSYMPPAGCAAAAAATPAVVTA 412
L VTP H + + + T A V +GD++ P+ V
Sbjct: 258 EGHTSKLLVTPNHLLFIKRSLSAGFLPTFAYRVQIGDLVQIY-----VNGTQLQPSKVVR 312
Query: 413 TGRVVAKGLYNPQTLVGSIVVDGFAAFTFTT 505
G+Y P T G+++VDG + T
Sbjct: 313 VSVEEQTGVYAPMTEHGTLLVDGVLTSCYAT 343
[70][TOP]
>UniRef100_Q66PH6 Sonic hedgehog n=1 Tax=Astyanax mexicanus RepID=Q66PH6_9TELE
Length = 429
Score = 54.7 bits (130), Expect = 4e-06
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 22/153 (14%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP ++ V ++ KA+ DL GD V +AD S +SD +FT DP+ + F + T
Sbjct: 195 CFPGSSHVRLKDSRQKALKDLKPGDSVLSADESGNLVYSDFIMFTDRDPSTRRVFYVIET 254
Query: 254 AAGV--LTVTPGH--YVLVNEGVRTAASAVVVGDVLSYMPPAGCAA-------------- 379
A V +T+T H ++L N T A+A + + + A+
Sbjct: 255 KAPVQKITLTAAHLIFILNNSTQSTQANANYANGAQAMVMTSTFASNVVPGQKVLVVDRN 314
Query: 380 AAAATPAVVTATGRVVAKGLYNPQTLVGSIVVD 478
P VV +G Y P T G+IVVD
Sbjct: 315 GGQLNPVVVERIYMEEHQGSYAPVTSHGTIVVD 347
[71][TOP]
>UniRef100_Q2QJG8 Hedgehog protein n=1 Tax=Capitella sp. I Grassle & Grassle, 1976
RepID=Q2QJG8_9ANNE
Length = 391
Score = 54.7 bits (130), Expect = 4e-06
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 5/140 (3%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAA----DGSFSDVFLFTHADPTAKSTFVTLTT 253
CF A +V+ G++ + L IGD ++A+ D +S V LF H + A ++FVTL T
Sbjct: 197 CFSADDTVKRVDGSSLPIQHLRIGDAIQASTDNGDVVYSPVILFLHREENAVASFVTLKT 256
Query: 254 AAG-VLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTATGRVVA 430
G LT++P H + E AS V +G ++ + P V T
Sbjct: 257 EGGRSLTLSPSHLIHTAEHGEIYASDVKIG---QHLLALNNNRSLDKDPVVAMTT--QYR 311
Query: 431 KGLYNPQTLVGSIVVDGFAA 490
+G++ P T +G+IVV+ ++
Sbjct: 312 RGVFAPLTAIGTIVVNDISS 331
[72][TOP]
>UniRef100_Q91610 Desert hedgehog protein 1 C-product n=1 Tax=Xenopus laevis
RepID=DHH1_XENLA
Length = 396
Score = 54.7 bits (130), Expect = 4e-06
Identities = 44/152 (28%), Positives = 68/152 (44%), Gaps = 12/152 (7%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP TA V + G K +++L IGD V D + S V LF H +P +TFV +
Sbjct: 198 CFPGTAMVMMGTGERKPLSELKIGDTVYTTDETGQLITSVVLLFLHRNPYKTATFVLIEA 257
Query: 254 AA--GVLTVTPGHYVLVNEG-----VRTAASAVVVGDVLS-YMPPAGCAAAAAATPAVVT 409
L VTP H + + + T A V +GD++ Y+ ++ ++
Sbjct: 258 EGHPSKLLVTPNHLLFIQSSSSAGFLPTFAYRVQIGDLVQIYVNGTQVQSSKVVRVSLEE 317
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTT 505
T G+Y P T G+++VDG + T
Sbjct: 318 QT------GVYAPMTEHGTLLVDGVLTSCYAT 343
[73][TOP]
>UniRef100_UPI000019B933 Sonic hedgehog protein precursor (SHH) [Contains: Sonic hedgehog
protein N-product; Sonic hedgehog protein C-product].
n=1 Tax=Rattus norvegicus RepID=UPI000019B933
Length = 437
Score = 54.3 bits (129), Expect = 5e-06
Identities = 54/165 (32%), Positives = 68/165 (41%), Gaps = 22/165 (13%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVT--- 244
CFP +A+V +E G TK + DL+ GDRV AAD +SD F D AK F
Sbjct: 199 CFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIET 258
Query: 245 -------LTTAAGVLTV--------TPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAA 379
L TAA +L V TPG L VR VV + G
Sbjct: 259 REPRERLLLTAAHLLFVAPHNDSGPTPGPSPLFASRVRPGQRVYVVAE------RGGDRR 312
Query: 380 AAAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
A AV + T R A G Y P T G+I+++ A + E
Sbjct: 313 LLPA--AVHSVTLREEAAGAYAPLTAHGTILINRVLASCYAVIEE 355
[74][TOP]
>UniRef100_Q63673 Sonic hedgehog protein C-product n=1 Tax=Rattus norvegicus
RepID=SHH_RAT
Length = 437
Score = 54.3 bits (129), Expect = 5e-06
Identities = 54/165 (32%), Positives = 68/165 (41%), Gaps = 22/165 (13%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVT--- 244
CFP +A+V +E G TK + DL+ GDRV AAD +SD F D AK F
Sbjct: 199 CFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIET 258
Query: 245 -------LTTAAGVLTV--------TPGHYVLVNEGVRTAASAVVVGDVLSYMPPAGCAA 379
L TAA +L V TPG L VR VV + G
Sbjct: 259 REPRERLLLTAAHLLFVAPHNDSGPTPGPSPLFASRVRPGQRVYVVAE------RGGDRR 312
Query: 380 AAAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
A AV + T R A G Y P T G+I+++ A + E
Sbjct: 313 LLPA--AVHSVTLREEAAGAYAPLTADGTILINRVLASCYAVIEE 355
[75][TOP]
>UniRef100_Q82KY9 Putative protoporphyrinogen oxidase n=1 Tax=Streptomyces
avermitilis RepID=Q82KY9_STRAW
Length = 474
Score = 54.3 bits (129), Expect = 5e-06
Identities = 54/176 (30%), Positives = 66/176 (37%), Gaps = 19/176 (10%)
Frame = +3
Query: 30 VTVTATLMSRPSPQTMTASASRRR---PASRWRAVRPRRWRTSPSATACGPPTAPSPTCS 200
V T T S P P S R P W A R WR SPS TA P +P S
Sbjct: 273 VCCTPTPWSSPCPPRPPPSCCAPRHPPPRPSWPASSTRPWRWSPSPTAAVGPASPKAAAS 332
Query: 201 CSRTQTRPQSRRL*R*PRRRVCSRSPQATTCW--SMKASAPPRRR---------WWSATS 347
T SR PR SR+ + TCW + ++ RRR W S +
Sbjct: 333 SCLPSTGAPSRHRRSPPRSGAGSRT-RTPTCWCCARRSGGTARRRSSAGTTPASWTSRAT 391
Query: 348 S----PTCPPRAAPPPPPPPPQLSRQRVGWSPRGCTTPRRWSA-ASSSMALLRSPS 500
+ P PPR +P P P R T R W A A++S + SPS
Sbjct: 392 TCARRPAWPPRRSPAASPAGPTACRSTPS------ATTRAWPASATTSPSCPASPS 441
[76][TOP]
>UniRef100_UPI00017B0D16 UPI00017B0D16 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B0D16
Length = 415
Score = 53.9 bits (128), Expect = 6e-06
Identities = 44/147 (29%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG----SFSDVFLFTHADPTAKSTFVTLTT 253
CFP +++V ++ G K + DL GDRV AADG ++SD F D + F + T
Sbjct: 202 CFPGSSTVTLQDGTKKLVKDLQSGDRVLAADGDGNPTYSDFITFIDRDSATRRLFHVIET 261
Query: 254 AAG-VLTVTPGHYVLV------NEGVRTA-ASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+G +T+T H + V +G+ AS V G + P A + T
Sbjct: 262 DSGQKITLTAAHLLFVARNGSGGDGMSAVFASQVRRGQKVMVSDPERGRLAPVTVKRIYT 321
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
G Y P T+ G++VVD A
Sbjct: 322 QE----HVGSYAPVTVQGNVVVDEILA 344
[77][TOP]
>UniRef100_Q4S4X6 Chromosome 6 SCAF14737, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4S4X6_TETNG
Length = 451
Score = 53.9 bits (128), Expect = 6e-06
Identities = 44/147 (29%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG----SFSDVFLFTHADPTAKSTFVTLTT 253
CFP +++V ++ G K + DL GDRV AADG ++SD F D + F + T
Sbjct: 236 CFPGSSTVTLQDGTKKLVKDLQSGDRVLAADGDGNPTYSDFITFIDRDSATRRLFHVIET 295
Query: 254 AAG-VLTVTPGHYVLV------NEGVRTA-ASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
+G +T+T H + V +G+ AS V G + P A + T
Sbjct: 296 DSGQKITLTAAHLLFVARNGSGGDGMSAVFASQVRRGQKVMVSDPERGRLAPVTVKRIYT 355
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
G Y P T+ G++VVD A
Sbjct: 356 QE----HVGSYAPVTVQGNVVVDEILA 378
[78][TOP]
>UniRef100_Q2PXN1 Sonic hedgehog n=1 Tax=Cyprinus carpio RepID=Q2PXN1_CYPCA
Length = 418
Score = 53.9 bits (128), Expect = 6e-06
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 14/149 (9%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTLTT 253
CFP +A V ++ G KA+ DL GD+V AADG+ +SD +FT D + F + T
Sbjct: 198 CFPGSALVALKDGRQKAVKDLNPGDKVLAADGNGKLVYSDFIMFTDRDSATRRVFYVIET 257
Query: 254 AAGV--LTVTPGHYVLVNEG--------VRTAASAVVVGDVLSYMPPAGCAAAAAATPAV 403
V +T+T H + V + AS+V G + + +G +
Sbjct: 258 KEPVEKITLTAAHLLFVLDNSTDDLHSMTAAFASSVRAGQKVMVVDDSG-----PLKSVI 312
Query: 404 VTATGRVVAKGLYNPQTLVGSIVVDGFAA 490
V +G + P T G+IVVD A
Sbjct: 313 VERIYTEEHQGSFAPVTAHGTIVVDRILA 341
[79][TOP]
>UniRef100_Q9GRA8 Hedgehog protein (Fragment) n=1 Tax=Gryllus bimaculatus
RepID=Q9GRA8_GRYBI
Length = 447
Score = 53.9 bits (128), Expect = 6e-06
Identities = 45/145 (31%), Positives = 61/145 (42%), Gaps = 10/145 (6%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG-----SFSDVFLFTHADPTAKSTFVTLT 250
CF A ++V+ GG A+A+L +G R A +FS V LF DP ++ T
Sbjct: 209 CFAAESTVQTPGGLC-ALAELRVGRRGAGAGPGHGRLAFSPVLLFLDRDPAPRTLLRVRT 267
Query: 251 TAAGVLTVTPGHYVLV-----NEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVTAT 415
+ L +TP H + V E A AV GD L AG A V+
Sbjct: 268 ASGRTLALTPSHLLPVARAGGGEPEARFADAVRPGDALLVAADAG---GAVRPDRVLHVD 324
Query: 416 GRVVAKGLYNPQTLVGSIVVDGFAA 490
G+ P T G++VVDG A
Sbjct: 325 AEATRGGVVAPLTAAGTVVVDGVLA 349
[80][TOP]
>UniRef100_B4KVA7 GI12133 n=1 Tax=Drosophila mojavensis RepID=B4KVA7_DROMO
Length = 1847
Score = 53.9 bits (128), Expect = 6e-06
Identities = 48/150 (32%), Positives = 62/150 (41%), Gaps = 2/150 (1%)
Frame = +3
Query: 54 SRPSPQTMTASASRRRPASRWRAVRPRRWRTSPSATACGPPTAPSPTCSCSRTQTRP--Q 227
SR T + S RRRP + PRR R S G + S + S SRT++R +
Sbjct: 1236 SRSKDSTRSPSPRRRRPM-----LSPRRGRFGKSRLGMGRSRSRSRSLSRSRTRSRSPLR 1290
Query: 228 SRRL*R*PRRRVCSRSPQATTCWSMKASAPPRRRWWSATSSPTCPPRAAPPPPPPPPQLS 407
RR+ P RR S SP P RRR +S + P PP PP
Sbjct: 1291 RRRVKVLPGRRRSSLSPPCKMLGPRSPPPPSRRRSYSRERCYSRSPLPFKPPSPP----- 1345
Query: 408 RQRVGWSPRGCTTPRRWSAASSSMALLRSP 497
R WSP +P R + + S + RSP
Sbjct: 1346 -MRRSWSPSRSRSPSRRRSRTRSRSRSRSP 1374
[81][TOP]
>UniRef100_UPI000186CBB9 hypothetical protein, conserved n=1 Tax=Pediculus humanus corporis
RepID=UPI000186CBB9
Length = 412
Score = 53.5 bits (127), Expect = 8e-06
Identities = 48/156 (30%), Positives = 68/156 (43%), Gaps = 25/156 (16%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG-----SFSDVFLFTHADPTAKSTFVTLT 250
CFP A V + G K+++ L IGD ++ D FS+V LF P ++ +
Sbjct: 188 CFPGGAKVRTKTGVKKSLSSLEIGDEIQVVDSETGDLKFSEVLLFLDKKPENVKHYLNIE 247
Query: 251 TAAG-VLTVTPGHYVLV--NEGV----------RTA-------ASAVVVGDVLSYMPPAG 370
T +G L VTP H ++ N G RT AS + +GD L G
Sbjct: 248 TKSGKKLQVTPSHLIVAIKNAGYQHDNNNLITERTGKNFETFFASEIEIGDALL---TVG 304
Query: 371 CAAAAAATPAVVTATGRVVAKGLYNPQTLVGSIVVD 478
T VV T V +G+Y P T+ G+IVV+
Sbjct: 305 RDGDEKLTDEVVNVT-NVRHEGVYAPLTVEGTIVVN 339
[82][TOP]
>UniRef100_UPI00003AB896 Sonic hedgehog protein precursor (SHH) [Contains: Sonic hedgehog
protein N-product; Sonic hedgehog protein C-product].
n=1 Tax=Gallus gallus RepID=UPI00003AB896
Length = 425
Score = 53.5 bits (127), Expect = 8e-06
Identities = 47/168 (27%), Positives = 70/168 (41%), Gaps = 25/168 (14%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVT--- 244
CFP +A+V +E G TK + DL+ GDRV AAD +SD F + +++ F
Sbjct: 201 CFPGSATVHLEHGGTKLVKDLSPGDRVLAADADGRLLYSDFLTFLDREDSSRKLFYVIET 260
Query: 245 -------LTTAAGVLTVTPGH-----------YVLVNEGVRTAASAVVVGDVLSYMPPAG 370
L TAA +L V P H L V+ V+G+ + PA
Sbjct: 261 RQPRARLLLTAAHLLFVAPQHNQSEATGSTSGQALFASNVKPGQRVYVLGEGGQQLLPA- 319
Query: 371 CAAAAAATPAVVTATGRVVAKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
+V + + R A G Y P T G+I+++ A + E
Sbjct: 320 ---------SVHSVSLREEASGAYAPLTAQGTILINRVLASCYAVIEE 358
[83][TOP]
>UniRef100_A1T591 Putative uncharacterized protein n=1 Tax=Mycobacterium vanbaalenii
PYR-1 RepID=A1T591_MYCVP
Length = 389
Score = 53.5 bits (127), Expect = 8e-06
Identities = 49/179 (27%), Positives = 75/179 (41%), Gaps = 14/179 (7%)
Frame = -2
Query: 501 VKVNAAKPSTTMLPTSVW-------------GLYNPLATTRPVAVTTAGVAAAAAAQPAG 361
VKV A P T+ P S G + +T P + TT+ + + P
Sbjct: 189 VKVEAQDPVATVPPGSPLPTFPDVPVAVLDPGTSSETTSTAPSSETTSPTSPSETTSPTS 248
Query: 360 GM*ERTSPTTTADAAVRTPSLTNT*WPGVTVSTPAAVVSVTNVDFAVGSACVNRNTSEKE 181
E TSPT+ ++ PS T P S+P+ S +VG+A
Sbjct: 249 PS-ETTSPTSPSETTSPAPSSETTSAP---TSSPSPTPSTAPTTTSVGAA---------P 295
Query: 180 PSAARTRSPMARSAIALVAPPSTSTLAVAGKHSLSSSVDSGDS-SASPSPSPDPSPEPS 7
PS++ + S A AP +TST V + S+ + + S +A P+P+P PSP P+
Sbjct: 296 PSSSAPATTTPTSTTATRAPSATSTTVVQSATTTSAPLSTSSSVAAPPTPTPSPSPTPT 354
[84][TOP]
>UniRef100_B0WA40 Hedgehog n=1 Tax=Culex quinquefasciatus RepID=B0WA40_CULQU
Length = 424
Score = 53.5 bits (127), Expect = 8e-06
Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Frame = +2
Query: 80 SECFPATASVEVEGGATKAMADLAIGDRVRAADGS----FSDVFLFTHADPTAKSTFVTL 247
S CF ++V+ G + +++L IG++V + D S +S+V +F D FV +
Sbjct: 216 SGCFTGDSTVQTINGEHRKLSELQIGEKVLSVDSSGRIVYSEVMMFMDRDTHQSREFVHI 275
Query: 248 TTAAGV-LTVTPGHYVLV-----NEGVRTAASAVVVGDVLSYMPPAGCAAAAAATPAVVT 409
T G LTVTP H V+V E A + GD + P V
Sbjct: 276 ETDGGAHLTVTPAHLVMVWQKEIGESRYLFADRIQEGDYVLVNIDNN------LEPRKVL 329
Query: 410 ATGRVVAKGLYNPQTLVGSIVVDGFAA 490
+++G+Y P T G+++VD AA
Sbjct: 330 RISAKLSQGVYAPLTSEGTVLVDSIAA 356
[85][TOP]
>UniRef100_Q90385 Sonic hedgehog protein C-product n=1 Tax=Cynops pyrrhogaster
RepID=SHH_CYNPY
Length = 432
Score = 53.5 bits (127), Expect = 8e-06
Identities = 49/165 (29%), Positives = 70/165 (42%), Gaps = 22/165 (13%)
Frame = +2
Query: 86 CFPATASVEVEGGATKAMADLAIGDRVRAADG----SFSDVFLFTHADPTAKSTFVTLTT 253
CFP +A+V +E G + DL GDRV AADG +SD LF + T + F + T
Sbjct: 201 CFPGSATVALEQGVRIPVKDLRPGDRVLAADGLGKLVYSDFLLFMDKEETVRKVFYVIET 260
Query: 254 AAGVLTVTPGHYVLVNEGVRTAASAVVVGDVLSYMPPAG----CAAAAAATPAVVTA--T 415
+ + +T H + V + S GD S AG A++ A V+T
Sbjct: 261 SRERVRLTAAHLLFVGQAHPGNDSG---GDFRSVFGSAGFRSMFASSVRAGHRVLTVDRE 317
Query: 416 GRVV------------AKGLYNPQTLVGSIVVDGFAAFTFTTXVE 514
GR + A G Y P T G++V+D A + E
Sbjct: 318 GRGLREATVERVYLEEATGAYAPVTAHGTVVIDRVLASCYAVIEE 362
[86][TOP]
>UniRef100_A4HWP8 Chromosome 15 (Fragment) n=1 Tax=Leishmania infantum
RepID=A4HWP8_LEIIN
Length = 1048
Score = 53.5 bits (127), Expect = 8e-06
Identities = 56/170 (32%), Positives = 69/170 (40%), Gaps = 18/170 (10%)
Frame = +3
Query: 57 RPSPQTMTASASRR------RPASRWRAV--RPRRWRTSPSATACGPPTAPSPTCSCSRT 212
R SP T T S R R + RWRA+ +P R+ P+AT C S
Sbjct: 15 RRSPPTATPCWSGRWARPSTRRSGRWRALCSKPAMRRSPPTATPCW-----------SGR 63
Query: 213 QTRPQSRRL*R*PRRRVCSRS------PQATTCWSMKASAPPRRR--WWSATSSPTCPPR 368
RP +RR R R +CS+ P AT CWS + + P RR W A S P
Sbjct: 64 WARPSTRRSGR--WRALCSKPAMRRSPPTATPCWSGRWARPSTRRSGRWRALCSK--PAM 119
Query: 369 AAPPPPPPPPQLSRQRVGWSPRGCTTPRRWSAASSSMALLRSP--SPPXW 512
PP P R W+ R RW A S A+ RSP + P W
Sbjct: 120 RRSPPAATPCWSGRWARPWTRRS----GRWRALCSKPAMRRSPPAATPCW 165
Score = 53.5 bits (127), Expect = 8e-06
Identities = 56/170 (32%), Positives = 69/170 (40%), Gaps = 18/170 (10%)
Frame = +3
Query: 57 RPSPQTMTASASRR------RPASRWRAV--RPRRWRTSPSATACGPPTAPSPTCSCSRT 212
R SP T T S R R + RWRA+ +P R+ P+AT C S
Sbjct: 645 RRSPPTATPCWSGRWARPSTRRSGRWRALCSKPAMRRSPPTATPCW-----------SGR 693
Query: 213 QTRPQSRRL*R*PRRRVCSRS------PQATTCWSMKASAPPRRR--WWSATSSPTCPPR 368
RP +RR R R +CS+ P AT CWS + + P RR W A S P
Sbjct: 694 WARPSTRRSGR--WRALCSKPAMRRSPPTATPCWSGRWARPSTRRSGRWRALCSK--PAM 749
Query: 369 AAPPPPPPPPQLSRQRVGWSPRGCTTPRRWSAASSSMALLRSP--SPPXW 512
PP P R W+ R RW A S A+ RSP + P W
Sbjct: 750 RRSPPAATPCWSGRWARPWTRRS----GRWRALCSKPAMRRSPPTATPCW 795