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[1][TOP]
>UniRef100_C5AML4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia glumae BGR1
           RepID=C5AML4_BURGB
          Length = 300

 Score =  140 bits (352), Expect = 7e-32
 Identities = 88/173 (50%), Positives = 105/173 (60%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V A L A    LA  A  GA +ID STI PA ++A    V A  G     
Sbjct: 60  VITMLPAAAHVRAALTAADGVLAGLA-AGATVIDSSTIDPASAQAFGELVRARGGA---- 114

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
                    +DAPVSGGT  AAAGTLT +VGGA+   A V P+L  MG+  VH GA G G
Sbjct: 115 --------FVDAPVSGGTGGAAAGTLTFMVGGAAADFARVGPVLGAMGKNLVHCGAVGMG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           QV K  NNLVLG SMA VAE+ AL AA G+ P     +L+TS+GRCW+AD Y+
Sbjct: 167 QVAKICNNLVLGISMAGVAESMALGAALGIDPKVLGGILSTSTGRCWSADTYN 219

[2][TOP]
>UniRef100_UPI00016A6DFB 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           oklahomensis C6786 RepID=UPI00016A6DFB
          Length = 298

 Score =  136 bits (343), Expect = 8e-31
 Identities = 82/172 (47%), Positives = 103/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V A L     +      GA+LID STI PA ++A    V           
Sbjct: 60  VVTMLPAAAHVRAVLTQDDGVLAGLGAGAMLIDSSTIDPASAQAFGELVR---------- 109

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G GG    +DAPVSGGT  AAAGTLT +VGG+      V P+LS MG+  VH GA G GQ
Sbjct: 110 GKGGAF--VDAPVSGGTGGAAAGTLTFMVGGSDADYERVKPVLSAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW+AD Y+
Sbjct: 168 VAKVCNNLVLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSADTYN 219

[3][TOP]
>UniRef100_Q2T4A5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           thailandensis E264 RepID=Q2T4A5_BURTA
          Length = 298

 Score =  135 bits (340), Expect = 2e-30
 Identities = 80/172 (46%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V   L   + +      GA++ID STI PA ++A    V          G
Sbjct: 60  VVTMLPAAAHVRGVLTQENGVLAGLAAGAMVIDSSTIDPASAQAFGELVR---------G 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G G  V   DAPVSGGT  AAAGTLT +VGG+    A V P+L+ MG+  VH GA G GQ
Sbjct: 111 GGGAFV---DAPVSGGTGGAAAGTLTFMVGGSDADYARVKPVLAAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSSDTYN 219

[4][TOP]
>UniRef100_UPI00016A412D 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           oklahomensis EO147 RepID=UPI00016A412D
          Length = 298

 Score =  135 bits (339), Expect = 2e-30
 Identities = 81/172 (47%), Positives = 102/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V A L     +      GA+LID STI PA ++A    V           
Sbjct: 60  VVTMLPAAAHVRAVLTQDDGVLAGLGAGAMLIDSSTIDPASAQAFGELVR---------- 109

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G GG    +DAPVSGGT  AAAGTLT +VGG+      V P+LS MG+  VH GA G GQ
Sbjct: 110 GKGGAF--VDAPVSGGTGGAAAGTLTFMVGGSDADYERVKPVLSAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA  L A+ G+ P   A ++ TS+GRCW+AD Y+
Sbjct: 168 VAKVCNNLVLGITMAGVSEAMTLGASLGIDPKVLAGIINTSTGRCWSADTYN 219

[5][TOP]
>UniRef100_A9ANK1 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Burkholderia multivorans
           RepID=A9ANK1_BURM1
          Length = 299

 Score =  135 bits (339), Expect = 2e-30
 Identities = 81/172 (47%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   H +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLTGEHGVLAGLESGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA AL  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMALGVALGIDPKVLAGIINTSTGRCWSSDTYN 219

[6][TOP]
>UniRef100_B9AYQ6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia multivorans
           CGD1 RepID=B9AYQ6_9BURK
          Length = 299

 Score =  135 bits (339), Expect = 2e-30
 Identities = 81/172 (47%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   H +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLTGEHGVLAGLESGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA AL  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMALGVALGIDPKVLAGIMNTSTGRCWSSDTYN 219

[7][TOP]
>UniRef100_C4I1J9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           pseudomallei MSHR346 RepID=C4I1J9_BURPS
          Length = 298

 Score =  134 bits (337), Expect = 4e-30
 Identities = 80/172 (46%), Positives = 103/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V A L   + +      GA++ID STI PA ++A    V          G
Sbjct: 60  VVTMLPAAAHVRAVLTQENGVLAGLAAGAMVIDSSTIDPASAQAFGELVR---------G 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G G  V   DAPVSGGT  AAAGTLT +VGG     A   P+L+ MG+  VH GA G GQ
Sbjct: 111 GGGAFV---DAPVSGGTGGAAAGTLTFMVGGDDADYARAKPVLAAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSSDTYN 219

[8][TOP]
>UniRef100_A3NHU9 3-hydroxyisobutyrate dehydrogenase n=13 Tax=Burkholderia
           pseudomallei RepID=A3NHU9_BURP6
          Length = 298

 Score =  134 bits (337), Expect = 4e-30
 Identities = 80/172 (46%), Positives = 103/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V A L   + +      GA++ID STI PA ++A    V          G
Sbjct: 60  VVTMLPAAAHVRAVLTQENGVLAGLAAGAMVIDSSTIDPASAQAFGELVR---------G 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G G  V   DAPVSGGT  AAAGTLT +VGG     A   P+L+ MG+  VH GA G GQ
Sbjct: 111 GGGAFV---DAPVSGGTGGAAAGTLTFMVGGDDADYARAKPVLAAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSSDTYN 219

[9][TOP]
>UniRef100_UPI00016A31CB 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ubonensis
           Bu RepID=UPI00016A31CB
          Length = 300

 Score =  134 bits (336), Expect = 5e-30
 Identities = 80/172 (46%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   H +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLTGEHGVLAGLGAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVQPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[10][TOP]
>UniRef100_B5S4D5 3-hydroxyisobutyrate dehydrogenase protein n=1 Tax=Ralstonia
           solanacearum RepID=B5S4D5_RALSO
          Length = 298

 Score =  134 bits (336), Expect = 5e-30
 Identities = 82/172 (47%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L A   +    P G  +ID STI P  ++A AA  AA         
Sbjct: 60  VITMLPAAAHVRSVLTADDGILAGIPKGVPIIDSSTIDPDSAKAFAALAAA--------- 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
              G V V DAPVSGGT  AAAGTLT +VGG++ +   V P+LS MG+  VH GA GAGQ
Sbjct: 111 --HGNVFV-DAPVSGGTGGAAAGTLTFMVGGSTAAFEQVRPVLSAMGKHLVHCGATGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NNLVLG +MA VAEA +L  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 168 GAKICNNLVLGITMAGVAEAMSLGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[11][TOP]
>UniRef100_A3RTI8 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Ralstonia solanacearum
           RepID=A3RTI8_RALSO
          Length = 298

 Score =  134 bits (336), Expect = 5e-30
 Identities = 82/172 (47%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L A   +    P G  +ID STI P  ++A AA  AA         
Sbjct: 60  VITMLPAAAHVRSVLTANDGILAGIPKGVPIIDSSTIDPDSAKAFAALAAA--------- 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
              G V V DAPVSGGT  AAAGTLT +VGG++ +   V P+LS MG+  VH GA GAGQ
Sbjct: 111 --HGNVFV-DAPVSGGTGGAAAGTLTFMVGGSTAAFEQVRPVLSAMGKHLVHCGATGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NNLVLG +MA VAEA +L  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 168 GAKICNNLVLGITMAGVAEAMSLGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[12][TOP]
>UniRef100_Q0B7D9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           AMMD RepID=Q0B7D9_BURCM
          Length = 300

 Score =  131 bits (330), Expect = 3e-29
 Identities = 79/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLDAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGAIGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[13][TOP]
>UniRef100_B1TCZ2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           MEX-5 RepID=B1TCZ2_9BURK
          Length = 300

 Score =  131 bits (330), Expect = 3e-29
 Identities = 79/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLDAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[14][TOP]
>UniRef100_B1FII3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           IOP40-10 RepID=B1FII3_9BURK
          Length = 300

 Score =  131 bits (330), Expect = 3e-29
 Identities = 79/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLDAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSEADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[15][TOP]
>UniRef100_Q399N0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia sp. 383
           RepID=Q399N0_BURS3
          Length = 299

 Score =  131 bits (329), Expect = 3e-29
 Identities = 79/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[16][TOP]
>UniRef100_A2WG09 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia dolosa
           AUO158 RepID=A2WG09_9BURK
          Length = 299

 Score =  131 bits (329), Expect = 3e-29
 Identities = 78/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID ST+ PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLAAGATVIDSSTVDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[17][TOP]
>UniRef100_A0B218 3-hydroxyisobutyrate dehydrogenase n=5 Tax=Burkholderia cenocepacia
           RepID=A0B218_BURCH
          Length = 299

 Score =  131 bits (329), Expect = 3e-29
 Identities = 79/172 (45%), Positives = 104/172 (60%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[18][TOP]
>UniRef100_A4JJ70 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           vietnamiensis G4 RepID=A4JJ70_BURVG
          Length = 299

 Score =  130 bits (328), Expect = 4e-29
 Identities = 78/172 (45%), Positives = 103/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLGAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+        P+L+ MG+  VH GA G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERAKPVLAAMGKNIVHCGATGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[19][TOP]
>UniRef100_Q13IC0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia xenovorans
           LB400 RepID=Q13IC0_BURXL
          Length = 298

 Score =  130 bits (327), Expect = 6e-29
 Identities = 82/173 (47%), Positives = 106/173 (61%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           ++TMLP+ A V + L A    LA  A  G  +ID STI PA  +ALA  +AA  G     
Sbjct: 60  VVTMLPAAAHVRSVLTADDGVLAGIAK-GVTIIDSSTIDPASVKALA-ELAAQHGNT--- 114

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
                   ++DAPVSGGT  AAAGTLT +VGG++ +   V P+LS MG+  VH G  G G
Sbjct: 115 --------LVDAPVSGGTGGAAAGTLTFMVGGSAAAYEQVKPVLSAMGKNIVHCGDTGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           QV K  NNLVLG +MA VAEA +L AA G+ P     ++ TS+GRCW++D Y+
Sbjct: 167 QVAKICNNLVLGITMAGVAEAMSLGAALGIDPKVLGGIINTSTGRCWSSDTYN 219

[20][TOP]
>UniRef100_B1YZ51 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           MC40-6 RepID=B1YZ51_BURA4
          Length = 300

 Score =  129 bits (325), Expect = 1e-28
 Identities = 78/172 (45%), Positives = 103/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V + L   + +      GA +ID STI PA ++A  A V        + G
Sbjct: 60  VITMLPAAPHVRSVLAGENGVLAGLDAGATVIDSSTIDPASAQAFGALVR-------EHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
           G+      +DAPVSGGT  AAAGTLT +VGG+      V P+L+ MG+  VH G  G GQ
Sbjct: 113 GA-----FVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGPTGMGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SMAAV+EA +L  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 VAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYN 219

[21][TOP]
>UniRef100_B1FSQ5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia graminis
           C4D1M RepID=B1FSQ5_9BURK
          Length = 308

 Score =  128 bits (322), Expect = 2e-28
 Identities = 78/172 (45%), Positives = 102/172 (59%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L A   +    P G  ++D STI PA  +A A  +A   G      
Sbjct: 60  VITMLPAAAHVRSVLTAEDGVLAGVPKGVTIVDSSTIDPASVKAFA-ELARQHGNT---- 114

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                   +DAPVSGGT  AAAGTLT +VGG++ +  AV P+LS MG+  VH G  G GQ
Sbjct: 115 -------FVDAPVSGGTGGAAAGTLTFMVGGSASAYEAVKPVLSAMGKNIVHCGDTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA VAEA +L  A G+     A ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLVLGVTMAGVAEAMSLGEALGIDVKVLAGIVNTSTGRCWSSDTYN 219

[22][TOP]
>UniRef100_Q3BVW5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Xanthomonas campestris
           pv. vesicatoria str. 85-10 RepID=Q3BVW5_XANC5
          Length = 295

 Score =  127 bits (320), Expect = 4e-28
 Identities = 75/170 (44%), Positives = 100/170 (58%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +  + P GA++ID STI P  +R +A            D 
Sbjct: 61  VISMLPASRHVEGVYLGESGILAQIPDGALVIDCSTIAPVSARRVA------------DA 108

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGGTA AAAGTLT IVGGA+D++    P+L  MG+ + HVG  GAGQ
Sbjct: 109 AKARGLTMLDAPVSGGTAGAAAGTLTFIVGGAADALERARPVLQAMGKNIFHVGDNGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MAA  EA AL  A G+ PV  + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAATGEALALGVAQGLDPVVLSQMMAVSTGRSWATEV 218

[23][TOP]
>UniRef100_B2UHN0 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Ralstonia pickettii
           RepID=B2UHN0_RALPJ
          Length = 297

 Score =  127 bits (320), Expect = 4e-28
 Identities = 83/173 (47%), Positives = 105/173 (60%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V   L A    LA  A  G  +ID STI PA ++ALAA +AA  G     
Sbjct: 60  VITMLPAAAHVRHVLTAEDGVLAGIAK-GVPIIDSSTIDPASAKALAA-LAAEHGNP--- 114

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
                    +DAPVSGGT  AAAGTLT +VGG++ +   V P+LS MG+  VH G  GAG
Sbjct: 115 --------FVDAPVSGGTGGAAAGTLTFMVGGSAAAFEQVRPVLSAMGKNLVHCGDTGAG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q  K  NNLVLG +MA VAEA +L  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 167 QGAKICNNLVLGITMAGVAEAMSLGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[24][TOP]
>UniRef100_A4VKU7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas stutzeri
           A1501 RepID=A4VKU7_PSEU5
          Length = 282

 Score =  127 bits (320), Expect = 4e-28
 Identities = 79/172 (45%), Positives = 101/172 (58%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V +     + L   +  G +LID STI P  +R +A + AA  G      
Sbjct: 47  IITMLPAAPHVKSVYLGENGLIASSRAGVMLIDCSTIDPHSAREVA-KAAAEHGNP---- 101

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                  +LDAPVSGGT  AAAGTLT +VGG+        P+L+ MG+  VH GA G GQ
Sbjct: 102 -------MLDAPVSGGTGGAAAGTLTFMVGGSDADFDRAQPILAAMGKNIVHCGAAGNGQ 154

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K ANN++LG SM  VAEA AL  A G+   T A V+ TSSGRCW++D Y+
Sbjct: 155 VAKVANNMLLGISMIGVAEAMALGVALGMDAKTLAGVINTSSGRCWSSDTYN 206

[25][TOP]
>UniRef100_C1DNT5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Azotobacter vinelandii
           DJ RepID=C1DNT5_AZOVD
          Length = 297

 Score =  125 bits (315), Expect = 1e-27
 Identities = 79/172 (45%), Positives = 101/172 (58%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++A V         L  +   G +LID STI P  +R +AA  AA   G     
Sbjct: 60  IITMLPASAHVKGVYLGEDGLLAQVRPGVMLIDSSTIDPLSAREVAA--AAREHGNP--- 114

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                  +LDAPVSGGTA AAAGTLT +VGG +       P+L+ MG+  VH G  G GQ
Sbjct: 115 -------MLDAPVSGGTAGAAAGTLTFMVGGETADFERARPVLAAMGKNIVHCGPAGNGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K ANN++LG SM  VAEA +L  A G+ P   A V+ +SSGRCW++D Y+
Sbjct: 168 VAKVANNMLLGISMIGVAEAMSLGVALGMEPKVLAGVINSSSGRCWSSDSYN 219

[26][TOP]
>UniRef100_Q8PMV9 3-hydroxyisobutirate dehydrogenase n=1 Tax=Xanthomonas axonopodis
           pv. citri RepID=Q8PMV9_XANAC
          Length = 295

 Score =  125 bits (314), Expect = 2e-27
 Identities = 74/170 (43%), Positives = 99/170 (58%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +  + P GA++ID STI P  +R +A            D 
Sbjct: 61  VISMLPASRHVEGLYLGESGILAQIPDGALVIDCSTIAPLSARKVA------------DA 108

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGGTA AAAGTLT IVGGA+D++    P+L  MG+ + HVG  GAGQ
Sbjct: 109 AKARGLTMLDAPVSGGTAGAAAGTLTFIVGGAADALERARPVLQAMGKNIFHVGDNGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MAA  EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAATGEALALGVAQGLDPAVLSQMMAVSTGRSWATEV 218

[27][TOP]
>UniRef100_Q8XS32 Probable 3-hydroxyisobutyrate dehydrogenase oxidoreductase protein
           n=1 Tax=Ralstonia solanacearum RepID=Q8XS32_RALSO
          Length = 298

 Score =  124 bits (312), Expect = 3e-27
 Identities = 79/171 (46%), Positives = 98/171 (57%), Gaps = 4/171 (2%)
 Frame = +1

Query: 28  ITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           ITMLP+ A V + L A   +      G  +ID STI P  ++ALAA   A          
Sbjct: 61  ITMLPAAAHVHSVLTADDGILAGIAKGVPIIDSSTIDPDSAKALAALATA---------- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
             G   V DAPVSGGT  AAAGTLT +VGG +     V P+LS MG+  VH G  GAGQ 
Sbjct: 111 -HGNPFV-DAPVSGGTGGAAAGTLTFMVGGGAAVFEQVRPVLSAMGKNLVHCGEAGAGQG 168

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            K  NNLVLG +MA VAEA +L  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 169 AKICNNLVLGITMAGVAEAMSLGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[28][TOP]
>UniRef100_B0RX36 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Xanthomonas campestris
           pv. campestris RepID=B0RX36_XANCB
          Length = 295

 Score =  123 bits (309), Expect = 7e-27
 Identities = 77/170 (45%), Positives = 100/170 (58%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +    P GA++ID STI PA +R +A   AA   G D   
Sbjct: 61  VISMLPASKHVEGLYLGDAGILAHIPAGALVIDCSTIAPAMARTVAT--AAHARGLD--- 115

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                  +LDAPVSGGTA AAAGTLT IVGGA+ ++    P+L  MG+ + HVG  GAGQ
Sbjct: 116 -------MLDAPVSGGTAGAAAGTLTFIVGGAAQALERARPVLQAMGKNLFHVGDNGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MAA  EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAATGEAIALGVAQGLDPAVLSQMMAVSTGRSWATEV 218

[29][TOP]
>UniRef100_UPI00016951B5 3-hydroxyisobutirate dehydrogenase n=1 Tax=Xanthomonas oryzae pv.
           oryzicola BLS256 RepID=UPI00016951B5
          Length = 295

 Score =  123 bits (308), Expect = 9e-27
 Identities = 73/170 (42%), Positives = 99/170 (58%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +  + P GA++ID STI P  +R +A            D 
Sbjct: 61  VISMLPASRHVEGLYLGDSGILAQIPHGALVIDCSTIAPLSARKVA------------DA 108

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +   + +LDAPVSGGTA AAAGTLT IVGGA++ +    P+L  MG+ + HVG  GAGQ
Sbjct: 109 ATARGLTMLDAPVSGGTAGAAAGTLTFIVGGAAEVLERARPVLQAMGKNIFHVGDNGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MAA  EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAATGEALALGVAQGLDPAVLSQMMAVSTGRSWATEV 218

[30][TOP]
>UniRef100_Q7NWA9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Chromobacterium
           violaceum RepID=Q7NWA9_CHRVO
          Length = 296

 Score =  123 bits (308), Expect = 9e-27
 Identities = 73/172 (42%), Positives = 100/172 (58%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   VA      + L  R P GA++ID STI    +R +A            +G
Sbjct: 61  VISMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVA------------EG 108

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGGTA AAAGTLT IVGGA++ +A   P+L  MG+ + H G  GAGQ
Sbjct: 109 AREKGLSMLDAPVSGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++LG  MA  AEA AL    G+ P   + +++ SSGR WA ++Y+
Sbjct: 169 TAKICNNMLLGILMAGTAEALALGVKNGLDPKVLSEIISKSSGRNWATELYN 220

[31][TOP]
>UniRef100_B8I9T1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8I9T1_METNO
          Length = 296

 Score =  123 bits (308), Expect = 9e-27
 Identities = 75/169 (44%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V   L  + P+ P GA++ID STI  A +RA  A+ A        + G 
Sbjct: 60  AVITMLPAGRHVLGLLDEILPQVPAGALVIDCSTIDVASARAAHAKAA--------ERGL 111

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVV 378
                 LDAPVSGG   A AGTLT + GG+ ++ A   PLL+ MGR V H G  GAGQ  
Sbjct: 112 AS----LDAPVSGGVGGARAGTLTFMAGGSPEAFARAEPLLARMGRKVVHCGEAGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  VAEA  LA   G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIGVAEAFVLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[32][TOP]
>UniRef100_B4SSP6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Stenotrophomonas
           maltophilia R551-3 RepID=B4SSP6_STRM5
          Length = 296

 Score =  123 bits (308), Expect = 9e-27
 Identities = 72/170 (42%), Positives = 97/170 (57%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +    P GA++ID STI PA +R ++   AA         
Sbjct: 61  VISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAA--------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + ++DAPVSGGTA A AGTLT IVGG  D++    P+L  MG+ + HVGA GAGQ
Sbjct: 112 ---RGLQMIDAPVSGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MA   EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEV 218

[33][TOP]
>UniRef100_B2SRY7 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Xanthomonas oryzae pv.
           oryzae RepID=B2SRY7_XANOP
          Length = 312

 Score =  123 bits (308), Expect = 9e-27
 Identities = 73/170 (42%), Positives = 99/170 (58%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +  + P GA++ID STI P  +R +A            D 
Sbjct: 78  VISMLPASRHVEGLYLGDSGILAQIPHGALVIDCSTIAPLSARKVA------------DA 125

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +   + +LDAPVSGGTA AAAGTLT IVGGA++ +    P+L  MG+ + HVG  GAGQ
Sbjct: 126 ATARGLTMLDAPVSGGTAGAAAGTLTFIVGGAAEVLERARPVLQAMGKNIFHVGDNGAGQ 185

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MAA  EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 186 VAKLCNNMALGVIMAATGEALALGVAQGLDPAVLSQMMAVSTGRSWATEV 235

[34][TOP]
>UniRef100_B2FI84 Putative 3-hydroxyisobutyrate dehydrogenase n=1
           Tax=Stenotrophomonas maltophilia K279a
           RepID=B2FI84_STRMK
          Length = 296

 Score =  123 bits (308), Expect = 9e-27
 Identities = 72/170 (42%), Positives = 97/170 (57%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +    P GA++ID STI PA +R ++   AA         
Sbjct: 61  VISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAA--------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + ++DAPVSGGTA A AGTLT IVGG  D++    P+L  MG+ + HVGA GAGQ
Sbjct: 112 ---RGLQMIDAPVSGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MA   EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEV 218

[35][TOP]
>UniRef100_B8LA10 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Stenotrophomonas sp.
           SKA14 RepID=B8LA10_9GAMM
          Length = 296

 Score =  123 bits (308), Expect = 9e-27
 Identities = 72/170 (42%), Positives = 97/170 (57%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         +    P GA++ID STI PA +R ++   AA         
Sbjct: 61  VISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAA--------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + ++DAPVSGGTA A AGTLT IVGG  D++    P+L  MG+ + HVGA GAGQ
Sbjct: 112 ---RGLQMIDAPVSGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           V K  NN+ LG  MA   EA AL  A G+ P   + ++A S+GR WA +V
Sbjct: 169 VAKLCNNMALGVIMAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEV 218

[36][TOP]
>UniRef100_B0UI80 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Methylobacterium sp.
           4-46 RepID=B0UI80_METS4
          Length = 296

 Score =  122 bits (307), Expect = 1e-26
 Identities = 75/168 (44%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V   L  + PR P GA+LID STI    +RA  AR A        + G  
Sbjct: 61  VVTMLPAGRHVLGLLDEILPRVPAGALLIDCSTIDVESARAAHARAA--------ERGLA 112

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                LDAPVSGG   A AGTLT + GGA ++ A   P+L+ MGR  VH G  GAGQ  K
Sbjct: 113 S----LDAPVSGGVGGARAGTLTFMAGGAPEAFARAEPVLARMGRRIVHCGEAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  VAEA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVAEAFVLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[37][TOP]
>UniRef100_B4EGQ5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia cenocepacia
           J2315 RepID=B4EGQ5_BURCJ
          Length = 296

 Score =  121 bits (304), Expect = 3e-26
 Identities = 74/172 (43%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA LID STI P   RA+A            D 
Sbjct: 60  IITMLPAAQHVRAVYLGDDGVLAGARAGATLIDCSTIDPGTVRAVA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG  +     + P+L  MGR V H G  G GQ
Sbjct: 108 AAQRDFPLADAPVSGGTGGAQAGTLTFMVGADAPLFERIRPVLLDMGRNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIEPAVLAGIINTSTGRCWSSDAYN 219

[38][TOP]
>UniRef100_B2TFI6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           phytofirmans PsJN RepID=B2TFI6_BURPP
          Length = 304

 Score =  121 bits (303), Expect = 3e-26
 Identities = 75/172 (43%), Positives = 99/172 (57%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L A   +      G  +ID STI PA  +A A  +A   G      
Sbjct: 60  VITMLPAAAHVRSVLSADDGVFAGIAKGVTIIDSSTIDPASVKAFA-ELAQQHGNT---- 114

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                   +DAPVSGGT  AAAGTLT +VGG++ +   V P+L+ MG+  VH G  G GQ
Sbjct: 115 -------FVDAPVSGGTGGAAAGTLTFMVGGSASAYEQVKPVLAAMGKNIVHCGDTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA VAEA +L  A G+       ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLVLGITMAGVAEAMSLGEALGIDAKVLGGIINTSTGRCWSSDTYN 219

[39][TOP]
>UniRef100_C0VIU2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter sp. ATCC
           27244 RepID=C0VIU2_9GAMM
          Length = 294

 Score =  121 bits (303), Expect = 3e-26
 Identities = 73/170 (42%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V         +      GA+ ID STI P   + +AA             
Sbjct: 60  VITMLPAAKHVKEVYLGEEGVLEVLKAGALCIDSSTIDPQTIKDIAALAQTK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +H+ DAPVSGGT  A AGTLT +VG    +   V P+LS MG+ V H G  GAGQ
Sbjct: 112 ----NIHICDAPVSGGTIGAQAGTLTFMVGANDQTFEEVKPVLSYMGKNVIHCGEVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL A  G+ P   A V+ TSSGRCW++++
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGAKLGIDPQALAGVVNTSSGRCWSSEI 217

[40][TOP]
>UniRef100_Q5Z106 Putative 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Nocardia
           farcinica RepID=Q5Z106_NOCFA
          Length = 299

 Score =  120 bits (302), Expect = 5e-26
 Identities = 74/168 (44%), Positives = 96/168 (57%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V      L P A  G + ID STI  A+++A A R  A          +G
Sbjct: 62  VITMLPNGKLVLDVYAELLPAAAPGTLFIDCSTIDVADAKAAAERAVA----------AG 111

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
            R   LDAPVSGG A AAAGTLT +VGGA+D  AA  P+L +MG + VH G  G GQ  K
Sbjct: 112 HRA--LDAPVSGGVAGAAAGTLTFMVGGAADDFAAALPVLEVMGGKVVHCGGAGVGQAAK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM A++EA  L    G+   +   V++T+SG+ WA   Y
Sbjct: 170 ICNNMLLGISMIALSEALVLGEKLGLSHQSFFDVVSTASGQSWALTSY 217

[41][TOP]
>UniRef100_B1K2I7 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Burkholderia cenocepacia
           RepID=B1K2I7_BURCC
          Length = 296

 Score =  120 bits (302), Expect = 5e-26
 Identities = 74/172 (43%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA LID STI P   RA+A            D 
Sbjct: 60  IITMLPAAQHVRAVYLGDDGVLAGARAGATLIDCSTIDPGTVRAVA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG        + P+L  MGR V H G  G GQ
Sbjct: 108 AAQRDFPLADAPVSGGTGGAQAGTLTFMVGADGALFERIRPVLLDMGRNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPTVLAGIINTSTGRCWSSDAYN 219

[42][TOP]
>UniRef100_Q143S6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia xenovorans
           LB400 RepID=Q143S6_BURXL
          Length = 297

 Score =  120 bits (301), Expect = 6e-26
 Identities = 74/172 (43%), Positives = 96/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V   L     +      G  ++D STI PA  R  AA             
Sbjct: 60  VITMLPAAAHVRGVLTGSEGVFSGIGDGVTIVDSSTIDPASVREFAALATE--------- 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
               +  ++DAPVSGGT  A+AGTLT +VGG+ ++ A V P+LS MGR  VH G  G GQ
Sbjct: 111 ---HKCVLVDAPVSGGTGGASAGTLTFMVGGSEEAYARVKPVLSTMGRNIVHCGDTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA VAEA AL  A G+       ++ TS+GR W++D Y+
Sbjct: 168 VAKICNNLVLGITMAGVAEAMALGDALGIDAKVLGGIMNTSTGRSWSSDTYN 219

[43][TOP]
>UniRef100_C8SEX3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Mesorhizobium
           opportunistum WSM2075 RepID=C8SEX3_9RHIZ
          Length = 294

 Score =  120 bits (301), Expect = 6e-26
 Identities = 74/168 (44%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V +    +AP+A  GA+ ID STI    +R   A   A   G        
Sbjct: 61  VITMLPAGKHVLSVYEDIAPKAKKGALFIDSSTIDVESARK--AHATAARNG-------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVVK 381
             +  +DAPVSGGT  AAAGTLT + GG+ D+ AA  P+L  M GR VH G  GAGQ  K
Sbjct: 111 --LLSIDAPVSGGTGGAAAGTLTFMAGGSDDAFAAAEPILKPMAGRIVHCGGDGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  VAEA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVAEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[44][TOP]
>UniRef100_Q13M21 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia xenovorans
           LB400 RepID=Q13M21_BURXL
          Length = 301

 Score =  120 bits (300), Expect = 8e-26
 Identities = 75/172 (43%), Positives = 96/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L A   +      G  +ID STI P   +A A             G
Sbjct: 60  VITMLPAAAHVRSVLTADDGIFAGIARGVTIIDSSTIDPVSVKAFAELA-------QQHG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
            S      +DAPVSGGT  AAAGTLT +VGG++     V P+LS MG+  VH G  G GQ
Sbjct: 113 NS-----FVDAPVSGGTGGAAAGTLTFMVGGSASVYEQVKPVLSAMGKNIVHCGDTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA VAEA +L  A G+       ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLVLGITMAGVAEAMSLGEALGIDAKVLGGIINTSTGRCWSSDTYN 219

[45][TOP]
>UniRef100_Q98L30 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Mesorhizobium loti
           RepID=Q98L30_RHILO
          Length = 294

 Score =  119 bits (298), Expect = 1e-25
 Identities = 75/168 (44%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V +    +AP+A   A+ ID STI   ES   A  +AA  G         
Sbjct: 61  VITMLPAGKHVLSVYEDIAPKAKKDALFIDSSTID-VESARKAHAIAAKHG--------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVVK 381
             +  +DAPVSGGT  AAAGTLT + GG++D+ AA  P+L  M GR VH G  GAGQ  K
Sbjct: 111 --LLSIDAPVSGGTGGAAAGTLTFMAGGSNDAFAAAEPVLKPMAGRIVHCGGDGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  VAEA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVAEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[46][TOP]
>UniRef100_B5WBL3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia sp. H160
           RepID=B5WBL3_9BURK
          Length = 297

 Score =  119 bits (298), Expect = 1e-25
 Identities = 75/172 (43%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + L     +         +ID STI PA  +A A  V           
Sbjct: 60  VITMLPAAAHVKSVLTGDDGILAGVGKNVTIIDSSTIDPASVKAFADLVK---------- 109

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
              G   V DAPVSGGT  AAAGTLT +VGG++     V P+LS MG+  VH G    GQ
Sbjct: 110 -QNGNTFV-DAPVSGGTGGAAAGTLTFMVGGSAAVFEHVRPVLSAMGKNIVHCGDTSTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLVLGITMAGVSEAMALGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[47][TOP]
>UniRef100_UPI0001874076 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas syringae pv.
           tomato T1 RepID=UPI0001874076
          Length = 296

 Score =  119 bits (297), Expect = 2e-25
 Identities = 74/176 (42%), Positives = 101/176 (57%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAAT-------LHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +ITMLP+ A V +        L  +AP  P     +D STI P   R +AA +AA  G  
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLKGIAPGVPA----VDCSTIDPQTIRDIAA-IAAQQG-- 112

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGAC 360
                    V + DAPVSGGT  A AGTLT +VGG++   AA+ P+L IMGR  VH G  
Sbjct: 113 ---------VVLGDAPVSGGTGGAQAGTLTFMVGGSTQHFAALKPVLEIMGRNIVHCGEV 163

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G GQ+ K  NN++L  SM  V+E+ AL +A G+     A ++ TS+GRCW+++ Y+
Sbjct: 164 GTGQIAKICNNMLLAISMIGVSESMALGSALGIDTEVLASIINTSTGRCWSSEAYN 219

[48][TOP]
>UniRef100_Q889G7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas syringae pv.
           tomato RepID=Q889G7_PSESM
          Length = 296

 Score =  119 bits (297), Expect = 2e-25
 Identities = 74/176 (42%), Positives = 101/176 (57%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAAT-------LHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +ITMLP+ A V +        L  +AP  P     +D STI P   R +AA +AA  G  
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLKGIAPGVPA----VDCSTIDPQTIRDIAA-IAAQQG-- 112

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGAC 360
                    V + DAPVSGGT  A AGTLT +VGG++   AA+ P+L IMGR  VH G  
Sbjct: 113 ---------VVLGDAPVSGGTGGAQAGTLTFMVGGSAQHFAALKPVLEIMGRNIVHCGEV 163

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G GQ+ K  NN++L  SM  V+E+ AL +A G+     A ++ TS+GRCW+++ Y+
Sbjct: 164 GTGQIAKICNNMLLAISMIGVSESMALGSALGIDTEVLASIINTSTGRCWSSEAYN 219

[49][TOP]
>UniRef100_UPI0001BBA84F 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter lwoffii
           SH145 RepID=UPI0001BBA84F
          Length = 296

 Score =  118 bits (296), Expect = 2e-25
 Identities = 70/172 (40%), Positives = 96/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +++MLP+   V       H +      G++ ID STI P   + +AA   A         
Sbjct: 60  VVSMLPAAKHVREVYLGEHGILEVLQAGSLCIDSSTIDPQTIQEVAAAAQAK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
               ++ V DAPVSGGT  A  GTLT +VG  + +  AV P+L  MG+  VH GA G GQ
Sbjct: 112 ----QIRVCDAPVSGGTLGAKDGTLTFMVGADAATFEAVKPVLGCMGKNLVHCGAVGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNL+LG SM AVAE  AL A  G+ P   A V+ +S+GRCW++++Y+
Sbjct: 168 VAKICNNLILGISMTAVAEGMALGAKLGIDPQALAGVINSSTGRCWSSEIYN 219

[50][TOP]
>UniRef100_Q1BME9 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Burkholderia cenocepacia
           RepID=Q1BME9_BURCA
          Length = 302

 Score =  118 bits (296), Expect = 2e-25
 Identities = 73/172 (42%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA LID STI P   RA+A            D 
Sbjct: 66  IITMLPAAQHVRAVYLGDDGVLAGARGGATLIDCSTIDPGTVRAVA------------DA 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG        + P+L  MG+ V H G  G GQ
Sbjct: 114 AAQRDFPLADAPVSGGTGGAQAGTLTFMVGADGALFERIRPVLLDMGKNVVHCGGTGTGQ 173

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 174 IAKICNNLLLGISMMGVSEAMALGAALGIDPTVLAGIINTSTGRCWSSDTYN 225

[51][TOP]
>UniRef100_B9Z3L6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Lutiella nitroferrum
           2002 RepID=B9Z3L6_9NEIS
          Length = 298

 Score =  118 bits (296), Expect = 2e-25
 Identities = 77/174 (44%), Positives = 96/174 (55%), Gaps = 6/174 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESR--ALAARVAAVMGGGDD 189
           +I+MLP+   V         L  R P G ++ID STI  A +R  A AARVA +      
Sbjct: 61  VISMLPAGKHVEGLYLGEDGLFARLPKGTLVIDCSTIAAASARKVAEAARVAGLC----- 115

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGA 366
                    +LDAPVSGGTA A AGTLT IVGG S  +    PLL  MG+ + H GA GA
Sbjct: 116 ---------MLDAPVSGGTAGATAGTLTFIVGGESADLERARPLLEAMGKNIFHAGASGA 166

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           GQ  K  NN++LG  M   AEA AL    G+ P   + ++A SSGR WA +VY+
Sbjct: 167 GQTAKICNNMLLGILMTGTAEALALGVRNGLDPKVLSDIIAKSSGRNWALEVYN 220

[52][TOP]
>UniRef100_Q3J1K8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacter sphaeroides
           2.4.1 RepID=Q3J1K8_RHOS4
          Length = 290

 Score =  118 bits (295), Expect = 3e-25
 Identities = 71/168 (42%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+ A +      + P    GAVL D ST+    +RA+AA   A   G        
Sbjct: 55  VVTMLPNGAILRQVAQEIVPAMTAGAVLCDCSTVDVESARAVAAEAEAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AAAGTLT +VGG+  + A V PL  IMG + VH G  GAGQ  K
Sbjct: 108 -----LDAPVSGGVGGAAAGTLTFMVGGSDAAFATVQPLFEIMGQKAVHCGGPGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[53][TOP]
>UniRef100_B9KJQ5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacter sphaeroides
           KD131 RepID=B9KJQ5_RHOSK
          Length = 280

 Score =  118 bits (295), Expect = 3e-25
 Identities = 71/168 (42%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+ A +      + P    GAVL D ST+    +RA+AA   A   G        
Sbjct: 45  VVTMLPNGAILRQVAQEIVPAMTAGAVLCDCSTVDVESARAVAAEAEAAGLGA------- 97

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AAAGTLT +VGG+  + A V PL  IMG + VH G  GAGQ  K
Sbjct: 98  -----LDAPVSGGVGGAAAGTLTFMVGGSDAAFATVQPLFEIMGQKAVHCGGPGAGQAAK 152

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 153 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 200

[54][TOP]
>UniRef100_A3PKM8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacter sphaeroides
           ATCC 17029 RepID=A3PKM8_RHOS1
          Length = 290

 Score =  118 bits (295), Expect = 3e-25
 Identities = 71/168 (42%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+ A +      + P    GAVL D ST+    +RA+AA   A   G        
Sbjct: 55  VVTMLPNGAILRQVAQEIVPAMTAGAVLCDCSTVDVESARAVAAEAEAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AAAGTLT +VGG+  + A V PL  IMG + VH G  GAGQ  K
Sbjct: 108 -----LDAPVSGGVGGAAAGTLTFMVGGSDAAFATVQPLFEIMGQKAVHCGGPGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[55][TOP]
>UniRef100_B9BJE0 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Burkholderia multivorans
           RepID=B9BJE0_9BURK
          Length = 296

 Score =  118 bits (295), Expect = 3e-25
 Identities = 72/172 (41%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V +     + +   A  GA LID STI P   R LA            D 
Sbjct: 60  VITMLPAAAHVRSVYEGENGVLAGARGGAWLIDCSTIDPDTVRTLA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG        + P+L +MG+ V H G  G GQ
Sbjct: 108 AAQRDCRLADAPVSGGTGGAQAGTLTFMVGAEPALFEQIRPVLLVMGKHVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKLCNNLLLGISMMGVSEAMALGVALGIDPSVLAGIINTSTGRCWSSDTYN 219

[56][TOP]
>UniRef100_B1Z280 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           MC40-6 RepID=B1Z280_BURA4
          Length = 296

 Score =  117 bits (294), Expect = 4e-25
 Identities = 71/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA  +D STI P   RA+A            D 
Sbjct: 60  VITMLPAAQHVRAVYLGDDGVLAGARAGATFVDCSTIDPDSVRAVA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG  +     + P+L  MG+ V H G  G GQ
Sbjct: 108 AAQHDFPLADAPVSGGTGGAQAGTLTFMVGAPAALFERIRPVLLDMGKNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPAVLAGIINTSTGRCWSSDTYN 219

[57][TOP]
>UniRef100_A8LME9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Dinoroseobacter shibae
           DFL 12 RepID=A8LME9_DINSH
          Length = 291

 Score =  117 bits (294), Expect = 4e-25
 Identities = 71/168 (42%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + +    L P    GAVL+D ST+    +RA+AA+  A   G        
Sbjct: 55  VITMLPNGAILRSVAAELIPAMAPGAVLLDCSTVDVESARAVAAQAEAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGGT  A AGTLT +VGG+  + A   PL  IMG + VH G  G GQ  K
Sbjct: 108 -----LDAPVSGGTGGAEAGTLTFMVGGSDAAFATARPLFDIMGQKAVHCGGAGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  E  ALA   G+       V++TSSG  W+ +VY
Sbjct: 163 ICNNMILGVTMVATCEGFALADKLGLDRQALFDVVSTSSGYSWSMNVY 210

[58][TOP]
>UniRef100_A9D9E3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Hoeflea phototrophica
           DFL-43 RepID=A9D9E3_9RHIZ
          Length = 284

 Score =  117 bits (294), Expect = 4e-25
 Identities = 72/169 (42%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP  A + A    + P    GAV ID ST+    +RA A  +AA  G        
Sbjct: 54  AVITMLPDGAILRAVYADIVPAGTKGAVFIDCSTVDVESARA-AHDMAAAQG-------- 104

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVV 378
              +  +DAPVSGG   A+AGTLT + GG+ +S A   PL  IMG + VH G  GAGQ  
Sbjct: 105 ---LLSVDAPVSGGVGGASAGTLTFMAGGSDESFARAAPLFEIMGQKAVHCGDAGAGQSA 161

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM    EA ALA   G+   +   V++TSSG CW+ + Y
Sbjct: 162 KICNNMLLGISMIGTCEAFALAEKLGLSAQSLFDVVSTSSGSCWSVNTY 210

[59][TOP]
>UniRef100_Q0BA28 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           AMMD RepID=Q0BA28_BURCM
          Length = 296

 Score =  117 bits (293), Expect = 5e-25
 Identities = 71/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA  +D STI P   RA+A            D 
Sbjct: 60  VITMLPAAQHVRAVYLGDDGVLAGARAGATFVDCSTIDPDTVRAVA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG  +     + P+L  MG+ V H G  G GQ
Sbjct: 108 AAQRDFPLADAPVSGGTGGAQAGTLTFMVGAPAALFERIRPVLLDMGKNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPAVLAGIINTSTGRCWSSDTYN 219

[60][TOP]
>UniRef100_B9J935 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Agrobacterium
           radiobacter K84 RepID=B9J935_AGRRK
          Length = 293

 Score =  117 bits (293), Expect = 5e-25
 Identities = 76/169 (44%), Positives = 92/169 (54%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP    V      +    P G +LID STI        +AR A  M G   D G 
Sbjct: 60  AVITMLPKGQHVLTVWTDILRSVPKGTLLIDSSTIDVD-----SARKAHAMAG---DVGC 111

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVV 378
                 LDAPVSGGT  AAAGTLT + GG+S+S AA  PLL +MG+  VH G  GAGQ  
Sbjct: 112 LS----LDAPVSGGTGGAAAGTLTFMAGGSSESFAAAKPLLEVMGKKIVHCGDAGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  V EA  L    G+       V +TSSG+CW+ + Y
Sbjct: 168 KICNNMILGISMIGVCEAFVLGEKLGLSHQALFDVASTSSGQCWSINTY 216

[61][TOP]
>UniRef100_A4JMS8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           vietnamiensis G4 RepID=A4JMS8_BURVG
          Length = 296

 Score =  117 bits (293), Expect = 5e-25
 Identities = 71/169 (42%), Positives = 92/169 (54%), Gaps = 4/169 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+   V A       +   A  GA  +D STI P   RA+A            D 
Sbjct: 60  VVTMLPAAQHVRAVYLGDDGVLAGARAGATFVDCSTIDPDTVRAIA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +       DAPVSGGT  A AGTLT +VG  +   A + PLL  MG+ V H G  G GQ
Sbjct: 108 AAQRNFAFADAPVSGGTGGAQAGTLTFMVGAEAALFARIRPLLLDMGKNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
           + K  NNL+LG SM  V+EA AL AA G+ PV  A ++ TS+GRCW+++
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPVVLAGIINTSTGRCWSSE 216

[62][TOP]
>UniRef100_B1FMF9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ambifaria
           IOP40-10 RepID=B1FMF9_9BURK
          Length = 296

 Score =  117 bits (293), Expect = 5e-25
 Identities = 71/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA  +D STI P   RA+A            D 
Sbjct: 60  VITMLPAAQHVRAVYLGDDGVLAGARAGATFVDCSTIDPDTVRAVA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG  +     + P+L  MG+ V H G  G GQ
Sbjct: 108 AAQRDFPLADAPVSGGTGGAQAGTLTFMVGAPAALFERIRPVLLDMGKNVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPAVLAGIINTSTGRCWSSDTYN 219

[63][TOP]
>UniRef100_UPI00016AF739 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           thailandensis MSMB43 RepID=UPI00016AF739
          Length = 189

 Score =  117 bits (292), Expect = 7e-25
 Identities = 60/110 (54%), Positives = 75/110 (68%), Gaps = 1/110 (0%)
 Frame = +1

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVV 378
           GG    +DAPVSGGT  AAAGTLT +VGG     A V P+L+ MG+  VH GA G GQV 
Sbjct: 1   GGGGAFVDAPVSGGTGGAAAGTLTFMVGGGDADYARVKPVLAAMGKNIVHCGATGMGQVA 60

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           K  NNLVLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW++D Y+
Sbjct: 61  KVCNNLVLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSSDTYN 110

[64][TOP]
>UniRef100_D0DCE0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Citreicella sp. SE45
           RepID=D0DCE0_9RHOB
          Length = 290

 Score =  117 bits (292), Expect = 7e-25
 Identities = 71/168 (42%), Positives = 94/168 (55%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + A    + P    GAVL+D ST+    +RA+A++  A   G        
Sbjct: 55  VITMLPNGAILRAVADEVIPAMAEGAVLLDCSTVDVESARAVASQAEAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AAAGTLT +VGG+  + A   PL  IMG + VH G  GAGQ  K
Sbjct: 108 -----LDAPVSGGIGGAAAGTLTFMVGGSDAAFAVGKPLFDIMGQKAVHCGPSGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+   +   V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQSMFDVVSTSSGYSWSMNAY 210

[65][TOP]
>UniRef100_B9B6P1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia multivorans
           CGD1 RepID=B9B6P1_9BURK
          Length = 296

 Score =  117 bits (292), Expect = 7e-25
 Identities = 73/172 (42%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V       + +   A  GA LID STI P   R LA            D 
Sbjct: 60  VITMLPAAAHVRGVYEGENGVLAGARGGAWLIDCSTIDPDTVRTLA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG        + P+L  MG+ V H G  G GQ
Sbjct: 108 AALRDCRLADAPVSGGTGGAQAGTLTFMVGAEPALFEQIRPVLLAMGKHVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKLCNNLLLGISMMGVSEAMALGAALGIDPSVLAGIINTSTGRCWSSDTYN 219

[66][TOP]
>UniRef100_Q0S0U3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodococcus jostii RHA1
           RepID=Q0S0U3_RHOSR
          Length = 301

 Score =  116 bits (291), Expect = 9e-25
 Identities = 76/164 (46%), Positives = 95/164 (57%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLPS   V      L P A  G + +D STI  A++RA AA +A          G+G
Sbjct: 61  IITMLPSGKHVLDVYADLVPAAAQGTLFLDCSTIDVADARA-AAELAV---------GAG 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
            R   +DAPVSGGT AA  GTLT +VGG +D+V   + LL  MG R V  G  GAGQ  K
Sbjct: 111 HRA--VDAPVSGGTVAADGGTLTFMVGGPADAVDQASSLLDAMGARIVRCGDSGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM AV+EA AL A  G+       V +T+SG+CWA
Sbjct: 169 ICNNMILGISMIAVSEAFALGAKLGLTDQALFDVSSTASGQCWA 212

[67][TOP]
>UniRef100_A1BAK2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Paracoccus denitrificans
           PD1222 RepID=A1BAK2_PARDP
          Length = 291

 Score =  116 bits (291), Expect = 9e-25
 Identities = 69/168 (41%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + A    + P    GAV  D ST+    +RA+A +  A   G        
Sbjct: 55  VITMLPNGAILRAVADEIVPAMAAGAVFCDCSTVDVESARAVAGQAQAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   A AGTLT +VGG++++   V PL  IMG + VH G  GAGQ  K
Sbjct: 108 -----LDAPVSGGVGGATAGTLTFMVGGSAEAFDKVKPLFDIMGQKAVHCGEAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRARMFDVVSTSSGYSWSMNAY 210

[68][TOP]
>UniRef100_Q46TC2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ralstonia eutropha
           JMP134 RepID=Q46TC2_RALEJ
          Length = 297

 Score =  116 bits (290), Expect = 1e-24
 Identities = 74/172 (43%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+ A V         +      G  L+D STI PA  R LAA  AA        G
Sbjct: 60  VMTMLPAAAHVRTAYLGDEGVLAGVRAGVPLVDSSTIDPATVRELAAAAAA-------HG 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                  + DAPVSGGT  A AGTLT +VG   D    V P+L+ MGR  VH G  G GQ
Sbjct: 113 NP-----LADAPVSGGTGGAQAGTLTFMVGATPDLFEQVKPVLANMGRNLVHCGDTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNL+LG SM  V+EA AL    G+     A ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLILGISMIGVSEAMALGVRLGIDANVLAGIVNTSTGRCWSSDTYN 219

[69][TOP]
>UniRef100_B1VV63 Putative 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces
           griseus subsp. griseus NBRC 13350 RepID=B1VV63_STRGG
          Length = 308

 Score =  116 bits (290), Expect = 1e-24
 Identities = 76/170 (44%), Positives = 94/170 (55%), Gaps = 3/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATL--HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           A+ITMLP+   V +      L   A  G + +D STI  A+SRA  A   A         
Sbjct: 61  AVITMLPAGRHVLSLYGPEGLLAAARPGTLFVDCSTIDVADSRAAHAAAEA--------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
            +G R   LDAPVSGG   A AGTLT + GG   + AA  PLLS+MGR  VH GA GAGQ
Sbjct: 112 -AGHRS--LDAPVSGGVVGAEAGTLTFMAGGEEAAFAAAEPLLSVMGRKAVHCGAAGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
             K  NN++LG SM AV+EA  LA + G+       V + +SG+CWA  V
Sbjct: 169 AAKICNNMILGVSMIAVSEAFVLAESLGLSDQALYDVASAASGQCWALTV 218

[70][TOP]
>UniRef100_A4SZ57 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Polynucleobacter
           necessarius subsp. asymbioticus QLW-P1DMWA-1
           RepID=A4SZ57_POLSQ
          Length = 298

 Score =  116 bits (290), Expect = 1e-24
 Identities = 75/185 (40%), Positives = 98/185 (52%), Gaps = 10/185 (5%)
 Frame = +1

Query: 4   TTPPPI------ALITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAA 156
           TTP  I       ++TMLP+   V +       +      G +LID STI P  +R +A 
Sbjct: 51  TTPAAILKEGVEVIVTMLPAAQHVKSVYLGNDGILSGNVDGVILIDSSTIDPMSAREVAK 110

Query: 157 RVAAVMGGGDDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG 336
             AA             +  +LDAPVSGGT  A AGTLT +VGG     A +  LL  MG
Sbjct: 111 AAAAK------------KALMLDAPVSGGTGGAEAGTLTFMVGGEEGLYAQMQSLLQAMG 158

Query: 337 RP-VHVGACGAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
           +  V+ GA G GQV K ANN++LG SM   AEA AL  + G+     A ++ TSSGRCW+
Sbjct: 159 KNIVYCGAAGNGQVAKVANNMLLGISMIGTAEAMALGVSLGMDAKVLAGIINTSSGRCWS 218

Query: 514 ADVYH 528
           +D Y+
Sbjct: 219 SDTYN 223

[71][TOP]
>UniRef100_D0C2A0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter sp.
           RUH2624 RepID=D0C2A0_9GAMM
          Length = 296

 Score =  116 bits (290), Expect = 1e-24
 Identities = 72/170 (42%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA   +         
Sbjct: 60  VITMLPAAKHVKEVYLGENGVLEVLKAGSLCIDSSTIDPQTIKDIAAVAQSK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   V P+LS MG+  VH G  GAGQ
Sbjct: 112 ----NIKICDAPVSGGTIGAQAGTLTFMVGADDQTFNEVKPVLSHMGKNIVHCGDVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ TSSGRCW++DV
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINTSSGRCWSSDV 217

[72][TOP]
>UniRef100_B5GWT3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GWT3_STRCL
          Length = 298

 Score =  116 bits (290), Expect = 1e-24
 Identities = 80/168 (47%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLH----ALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+   V   L     ALA   P GAVL+DMSTI P+ S+ +AA +A   G     
Sbjct: 63  VITMLPNGPHVREALTGPDGALAAMRP-GAVLVDMSTIDPSTSKEMAA-LAERHG----- 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAG 369
                 V +LDAPVSG +A A  GTLT++VGG   ++  + PLL  +GR V H G  GAG
Sbjct: 116 ------VRMLDAPVSGSSAGAVEGTLTVMVGGDPGTLDELRPLLGELGRTVVHCGPNGAG 169

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             VK AN ++ GASMAAVAE+ ALA   GV P     V++ SSG CWA
Sbjct: 170 VSVKLANQIIAGASMAAVAESYALAQRLGVDPRLLFDVVSASSGDCWA 217

[73][TOP]
>UniRef100_A9ALV3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia multivorans
           ATCC 17616 RepID=A9ALV3_BURM1
          Length = 296

 Score =  115 bits (289), Expect = 1e-24
 Identities = 72/172 (41%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V         +   A  GA LID STI P   R LA            D 
Sbjct: 60  VITMLPAAAHVRGVYEGDDGVLAGARGGAWLIDCSTIDPDTVRTLA------------DA 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            +     + DAPVSGGT  A AGTLT +VG        + P+L  MG+ V H G  G GQ
Sbjct: 108 AAQRDCRLADAPVSGGTGGAQAGTLTFMVGAEPALFERIRPVLLAMGKHVVHCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL  A G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKLCNNLLLGISMMGVSEAMALGVALGIDPSVLAGIINTSTGRCWSSDTYN 219

[74][TOP]
>UniRef100_A3M0Z6 3-hydroxyisobutyrate dehydrogenase n=4 Tax=Acinetobacter baumannii
           RepID=A3M0Z6_ACIBT
          Length = 296

 Score =  115 bits (289), Expect = 1e-24
 Identities = 72/170 (42%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA   +         
Sbjct: 60  VITMLPAAKHVKEVYLGENGVLEVLKAGSLCIDSSTIDPQTIKDIAAVAHSK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   V P+LS MG+  VH G  GAGQ
Sbjct: 112 ----NIKICDAPVSGGTIGAQAGTLTFMVGADEQTFNEVKPVLSHMGKNIVHCGDVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ TSSGRCW++DV
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINTSSGRCWSSDV 217

[75][TOP]
>UniRef100_B0VNG1 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Acinetobacter baumannii
           RepID=B0VNG1_ACIBS
          Length = 296

 Score =  115 bits (289), Expect = 1e-24
 Identities = 72/170 (42%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA   +         
Sbjct: 60  VITMLPAAKHVKEVYLGENGVLEVLKAGSLCIDSSTIDPQTIKDIAAVAHSK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   V P+LS MG+  VH G  GAGQ
Sbjct: 112 ----NIKICDAPVSGGTIGAQAGTLTFMVGADEQTFNEVKPVLSHMGKNIVHCGDVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ TSSGRCW++DV
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINTSSGRCWSSDV 217

[76][TOP]
>UniRef100_B2JLY8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia phymatum
           STM815 RepID=B2JLY8_BURP8
          Length = 297

 Score =  115 bits (288), Expect = 2e-24
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V A L     +         +ID STI PA S    A +A + G      
Sbjct: 60  VITMLPAAAHVRAVLAGADGILAGIAKNVTIIDSSTIDPA-SVTTFAELANLNGNT---- 114

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                   +DAPVSGGT  A AGTLT +VGG+  +   V P+L  MG+  VH G    GQ
Sbjct: 115 -------FVDAPVSGGTGGATAGTLTFMVGGSPTAYEHVKPVLQAMGKNIVHCGETSTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG +MA V+EA AL  A G+ P     ++ TS+GRCW++D Y+
Sbjct: 168 VAKICNNLVLGITMAGVSEAMALGEALGIDPKVLGGIINTSTGRCWSSDTYN 219

[77][TOP]
>UniRef100_B0KHT0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas putida GB-1
           RepID=B0KHT0_PSEPG
          Length = 295

 Score =  115 bits (288), Expect = 2e-24
 Identities = 74/173 (42%), Positives = 99/173 (57%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL----HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +        LA   P G   +D STI P  +R ++   A   G G D 
Sbjct: 60  VITMLPAAAHVRSVYLNEDGVLAGIRP-GTPTVDCSTIDPQTARDVSKAAA---GKGVDM 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G         DAPVSGGT  AAAGTLT +VG +++  A++ P+L  MGR  VH G  G G
Sbjct: 116 G---------DAPVSGGTGGAAAGTLTFMVGASAELFASLKPVLEQMGRNIVHCGEVGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 QIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 219

[78][TOP]
>UniRef100_A5FW65 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acidiphilium cryptum
           JF-5 RepID=A5FW65_ACICJ
          Length = 299

 Score =  115 bits (288), Expect = 2e-24
 Identities = 74/172 (43%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           A+ITMLPS   V A   A   + P A  G + ID STI    +RA  A  A         
Sbjct: 60  AVITMLPSGPIVRAVYEAADGILPAARAGTLFIDCSTIDVDSARAAHAMAA--------- 110

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
              G  +  LDAPVSGG   A+AGTLT + GG++++     PLL+ MGR  VH G  GAG
Sbjct: 111 ---GRGMLALDAPVSGGVGGASAGTLTFMAGGSAEAFERGEPLLAAMGRRIVHCGGAGAG 167

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           Q  K  NN++LG SM AV+EA ALA   G+       V +T+SG+CW+   Y
Sbjct: 168 QAAKICNNMILGISMIAVSEAFALADRLGLDRQKLFDVASTASGQCWSLTSY 219

[79][TOP]
>UniRef100_UPI0001B5746A 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces sp. SPB78
           RepID=UPI0001B5746A
          Length = 305

 Score =  115 bits (287), Expect = 2e-24
 Identities = 68/167 (40%), Positives = 91/167 (54%), Gaps = 1/167 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +I+MLP+   V      +   A  G + +D STI  A++RA+ A               G
Sbjct: 68  VISMLPAGRHVLGLYEDILGAARPGTLFVDCSTIDVADARAVHALA------------EG 115

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
             +  LDAPVSGG   A AGTLT +VGG  +  A   PLL +MG+ V H GA G+GQ  K
Sbjct: 116 RGMRCLDAPVSGGVVGAEAGTLTFMVGGGEEEFAEALPLLDVMGKKVVHCGAAGSGQAAK 175

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
             NN++LG SM AV+EA  LA + G+       V +T+SG+CWA  V
Sbjct: 176 ICNNMILGVSMIAVSEAFVLAESLGLSHQALYDVASTASGQCWALSV 222

[80][TOP]
>UniRef100_Q394G9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia sp. 383
           RepID=Q394G9_BURS3
          Length = 296

 Score =  115 bits (287), Expect = 2e-24
 Identities = 72/172 (41%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       +   A  GA LID STI P   RA+A   A          
Sbjct: 60  VITMLPAAQHVRAVYLGDDGVLAGARAGAALIDCSTIDPGTVRAVAEAAAQ--------- 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                  + DAPVSGGT  A AGTLT +VG  +     + P+L  MG+ V   G  G GQ
Sbjct: 111 ---RDFPLADAPVSGGTGGALAGTLTFMVGADAALFERIRPVLLDMGKNVVQCGGTGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL AA G+ P   A ++ TS+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMMGVSEAMALGAALGIDPAVLAGIINTSTGRCWSSDAYN 219

[81][TOP]
>UniRef100_Q2IY82 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris HaA2 RepID=Q2IY82_RHOP2
          Length = 295

 Score =  115 bits (287), Expect = 2e-24
 Identities = 71/168 (42%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V A  + + P A  G+++ID STI   ES A+ A   A  GG        
Sbjct: 61  IVTMLPAGKHVLAVWNEILPHAAPGSLIIDCSTID-VES-AVQAHTLAAKGG-------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  +DAPVSGGT  A A TLT + GG+  + AA  P+L  MG+  VH G  GAGQ  K
Sbjct: 111 --IASIDAPVSGGTGGAKAATLTFMAGGSEAAFAAAKPVLEQMGKKIVHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM AV EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIAVGEAFTLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[82][TOP]
>UniRef100_B3R9Y6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Cupriavidus taiwanensis
           RepID=B3R9Y6_CUPTR
          Length = 301

 Score =  115 bits (287), Expect = 2e-24
 Identities = 78/170 (45%), Positives = 95/170 (55%), Gaps = 5/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAA----TLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +    T   LA   P G  L+D STI PA  R LAA   A        
Sbjct: 60  VITMLPAAAHVRSAYLGTDGVLAGVRP-GVPLVDSSTIDPATVRELAAAAEA-------H 111

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G +     + DAPVSGGT  A AGTLT +VG +    A V P+L+ MGR  VH G  G G
Sbjct: 112 GNA-----LADAPVSGGTVGAQAGTLTFMVGASEALFAQVRPVLAGMGRNLVHCGGTGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
           QV K  NNL+LG SM  V+EA AL    G+     A ++ TS+GRCWA+D
Sbjct: 167 QVAKICNNLILGISMIGVSEAMALGVKLGIDANVLAGIVNTSTGRCWASD 216

[83][TOP]
>UniRef100_A9INM6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bordetella petrii DSM
           12804 RepID=A9INM6_BORPD
          Length = 295

 Score =  115 bits (287), Expect = 2e-24
 Identities = 70/171 (40%), Positives = 98/171 (57%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL--HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           +I+MLP++  V A    + L       A++I+ STI P  +R +AA   A          
Sbjct: 61  VISMLPASKHVEALYLDNDLLSSIDPSALVIECSTIAPDSARKVAAAAQA---------- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
               + ++DAPVSGGT  AAAGTLT IVGG  D++    P+L  MG+ + H G  GAGQV
Sbjct: 111 --RGLAMIDAPVSGGTGGAAAGTLTFIVGGEPDALQRAMPVLQNMGKNIFHAGTAGAGQV 168

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            K  NN++LG  MA  +EA AL  A G+ P   + ++A SSGR WA ++Y+
Sbjct: 169 AKICNNMLLGILMAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYN 219

[84][TOP]
>UniRef100_Q1YGH6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Aurantimonas
           manganoxydans SI85-9A1 RepID=Q1YGH6_MOBAS
          Length = 287

 Score =  115 bits (287), Expect = 2e-24
 Identities = 74/171 (43%), Positives = 93/171 (54%), Gaps = 3/171 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDG 195
           A+ITMLP+   V A    +  +A  GA+LID ST+    +RA    AR A ++       
Sbjct: 54  AVITMLPNGDIVRAVHADIVRQAQAGALLIDCSTVDVDSARAAHDMAREAGLLS------ 107

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   LDAPVSGGT  AAAGTLT +VGG+  + A   PL  IMG + VH G  GAGQ
Sbjct: 108 --------LDAPVSGGTGGAAAGTLTFMVGGSDAAFAKGKPLFDIMGQKAVHCGEAGAGQ 159

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             K  NN++LG SM  V EA  LA   G+       V +TSSG CW+ + Y
Sbjct: 160 AAKICNNMILGISMIGVCEAFHLADKLGLDRQAMFDVASTSSGSCWSINTY 210

[85][TOP]
>UniRef100_UPI0001BB591C 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter
           calcoaceticus RUH2202 RepID=UPI0001BB591C
          Length = 296

 Score =  114 bits (286), Expect = 3e-24
 Identities = 71/170 (41%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA   +         
Sbjct: 60  VITMLPAAKHVKEVYLGENGVLEVLKAGSLCIDSSTIDPQTIKDIAAVAHSK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   V P+LS MG+  VH G  GAGQ
Sbjct: 112 ----NIKICDAPVSGGTIGAQAGTLTFMVGADEQTFNEVKPVLSHMGKNIVHCGEVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ +SSGRCW++DV
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINSSSGRCWSSDV 217

[86][TOP]
>UniRef100_Q88E02 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas putida
           KT2440 RepID=Q88E02_PSEPK
          Length = 295

 Score =  114 bits (286), Expect = 3e-24
 Identities = 74/173 (42%), Positives = 99/173 (57%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL----HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +        LA   P G   +D STI P  +R ++   AA    G D 
Sbjct: 60  VITMLPAAAHVRSVYLNEDGVLAGIRP-GTPTVDCSTIDPQTARDVSKAAAAK---GVDM 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G         DAPVSGGT  AAAGTLT +VG +++  A++ P+L  MGR  VH G  G G
Sbjct: 116 G---------DAPVSGGTGGAAAGTLTFMVGASTELFASLKPVLEQMGRNIVHCGEVGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 QIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 219

[87][TOP]
>UniRef100_B2I0V4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter baumannii
           ACICU RepID=B2I0V4_ACIBC
          Length = 296

 Score =  114 bits (286), Expect = 3e-24
 Identities = 71/170 (41%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA   +         
Sbjct: 60  VITMLPAAKHVKEVYLGENGVLEVLKAGSLCIDSSTIDPQTIKDIAAVAHSK-------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   + P+LS MG+  VH G  GAGQ
Sbjct: 112 ----NIKICDAPVSGGTIGAQAGTLTFMVGADEQTFNELKPVLSHMGKNIVHCGDVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ TSSGRCW++DV
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINTSSGRCWSSDV 217

[88][TOP]
>UniRef100_B1J3N8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas putida W619
           RepID=B1J3N8_PSEPW
          Length = 295

 Score =  114 bits (286), Expect = 3e-24
 Identities = 74/173 (42%), Positives = 98/173 (56%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL----HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +        LA   P G   +D STI P  +R ++   AA    G D 
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLAGVRP-GTPTVDCSTIDPQTAREVSKAAAAK---GVDM 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G         DAPVSGGT  AAAGTLT +VG +++  A + P+L  MGR  VH G  G G
Sbjct: 116 G---------DAPVSGGTGGAAAGTLTFMVGASTELFATLKPVLEQMGRNIVHCGEVGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 QIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 219

[89][TOP]
>UniRef100_A5W940 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas putida F1
           RepID=A5W940_PSEP1
          Length = 295

 Score =  114 bits (286), Expect = 3e-24
 Identities = 74/173 (42%), Positives = 100/173 (57%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +   +    LA   P G   +D STI P  +R ++   AA    G D 
Sbjct: 60  VITMLPAAAHVRSVYLSEDGVLAGIRP-GTPTVDCSTIDPQTARDVSKAAAAK---GVDM 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G         DAPVSGGT  AAAGTLT +VG +++  A++ P+L  MGR  VH G  G G
Sbjct: 116 G---------DAPVSGGTGGAAAGTLTFMVGASTELFASLKPVLEQMGRNIVHCGEVGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 QIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 219

[90][TOP]
>UniRef100_A5EHM7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bradyrhizobium sp. BTAi1
           RepID=A5EHM7_BRASB
          Length = 296

 Score =  114 bits (286), Expect = 3e-24
 Identities = 71/169 (42%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A++TMLP+   V A  + + P    GA++ID STI    +RA  A +AA  G        
Sbjct: 60  AVVTMLPAGKHVLAVWNEVVPAMAKGALIIDSSTIDVESARAAHA-LAAKHG-------- 110

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVV 378
              +  +DAPVSGGT  A A TLT + GG   + AA  P+L  MG+  VH G  GAGQ  
Sbjct: 111 ---IAAIDAPVSGGTGGAKAATLTFMCGGEEGAFAAAKPILEKMGKKIVHCGGAGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM AV+EA AL    G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIAVSEAFALGEKLGLSHQALFDVASTSSGQCWSLTSY 216

[91][TOP]
>UniRef100_Q76KL5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas putida
           RepID=Q76KL5_PSEPU
          Length = 295

 Score =  114 bits (286), Expect = 3e-24
 Identities = 74/173 (42%), Positives = 99/173 (57%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL----HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+ A V +        LA   P G   +D STI P  +R ++   AA    G D 
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLAGIRP-GTPTVDCSTIDPQTARDVSKAAAAK---GVDM 115

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
           G         DAPVSGGT  AAAGTLT +VG +++  A++ P+L  MGR  VH G  G G
Sbjct: 116 G---------DAPVSGGTGGAAAGTLTFMVGASAELFASLKPVLEQMGRNIVHCGEVGTG 166

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 QIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 219

[92][TOP]
>UniRef100_B6BEV1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacterales
           bacterium Y4I RepID=B6BEV1_9RHOB
          Length = 291

 Score =  114 bits (286), Expect = 3e-24
 Identities = 70/169 (41%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+ A +      + P    GA LID ST+    +RA+AA+ A        D G 
Sbjct: 54  AVITMLPNGAILRLVAAEVIPAMAKGATLIDCSTVDVDSARAVAAQAA--------DAG- 104

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVV 378
              +  +DAPVSGG   AA GTLT + GG++++ A   PL  IMG + VH G  GAGQ  
Sbjct: 105 ---LMFVDAPVSGGIGGAAGGTLTFMAGGSAEAFAKAEPLFDIMGQKAVHCGEAGAGQAA 161

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 162 KICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[93][TOP]
>UniRef100_A4EVS2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseobacter sp.
           SK209-2-6 RepID=A4EVS2_9RHOB
          Length = 290

 Score =  114 bits (286), Expect = 3e-24
 Identities = 68/168 (40%), Positives = 88/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + A    + P    GA L+D ST+    +RA+AA  A             
Sbjct: 55  VITMLPNGAILRAVAKEVLPAMSAGAALVDCSTVDVDSARAVAAEAAEAS---------- 104

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AA GTLT + GG  D+ A   PL  IMG + VH GA GAGQ  K
Sbjct: 105 --LLFVDAPVSGGIGGAAGGTLTFMAGGTEDAFAKALPLFDIMGQKAVHCGAAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M    EA ALA   G+       V++TSSG  W  + Y
Sbjct: 163 ICNNMILGVTMIGTCEAFALADKLGLDRQKMFDVVSTSSGYSWTMNAY 210

[94][TOP]
>UniRef100_A3XC07 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseobacter sp. MED193
           RepID=A3XC07_9RHOB
          Length = 290

 Score =  114 bits (286), Expect = 3e-24
 Identities = 67/168 (39%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + A  + + P    GA L+D ST+    +RA+A + AA            
Sbjct: 55  VITMLPNGQILRAVANDVVPAMQAGAALVDCSTVDVDSARAVAEQAAAA----------- 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AA GTLT + GG++D+ A   PL  IMG + VH G  GAGQ  K
Sbjct: 104 -ELLFVDAPVSGGIGGAAGGTLTFMAGGSADAFAKAEPLFDIMGQKAVHCGEAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W  + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWTMNAY 210

[95][TOP]
>UniRef100_UPI00016A6B89 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia ubonensis
           Bu RepID=UPI00016A6B89
          Length = 223

 Score =  114 bits (285), Expect = 4e-24
 Identities = 69/146 (47%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
 Frame = +1

Query: 88  APVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSGGRVHVL-DAPVSGGTAAAAAG 264
           A  GA LID STI P   RA+A   A              R H L DAPVSGGTA A AG
Sbjct: 11  ARAGATLIDCSTIDPGTVRAIADAAAR-------------RDHPLADAPVSGGTAGAQAG 57

Query: 265 TLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVKAANNLVLGASMAAVAEATAL 441
           TLT +VG  +     + P+L  MG+ V H G  G GQ+ K  NNL+LG SM  V+EA AL
Sbjct: 58  TLTFMVGAHAALFEQIRPVLLDMGKNVVHCGGTGTGQIAKICNNLLLGISMMGVSEAMAL 117

Query: 442 AAAAGVPPVTTAVVLATSSGRCWAAD 519
            AA G+ P   A ++ TS+GRCW++D
Sbjct: 118 GAALGIEPTVLAGIINTSTGRCWSSD 143

[96][TOP]
>UniRef100_Q1IFC8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas entomophila
           L48 RepID=Q1IFC8_PSEE4
          Length = 296

 Score =  114 bits (285), Expect = 4e-24
 Identities = 74/174 (42%), Positives = 99/174 (56%), Gaps = 6/174 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL-----HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDD 189
           +ITMLP+ A V +         LA   P G   +D STI P  +R ++   AA    G D
Sbjct: 60  VITMLPAAAHVRSVYLDEETGVLAGIRP-GTPTVDCSTIDPQTARDVSKAAAAK---GVD 115

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGA 366
            G         DAPVSGGT  AAAGTLT +VG +++  A + P+L+ MGR  VH G  G 
Sbjct: 116 MG---------DAPVSGGTGGAAAGTLTFMVGASAELFATLQPVLAQMGRNIVHCGEVGT 166

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           GQ+ K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 167 GQIAKICNNLLLGISMIGVSEAMALGNALGIDTKVLAGIINSSTGRCWSSDTYN 220

[97][TOP]
>UniRef100_Q0K1Z3 3-Hydroxyisobutyrate dehydrogenase n=1 Tax=Ralstonia eutropha H16
           RepID=Q0K1Z3_RALEH
          Length = 301

 Score =  114 bits (285), Expect = 4e-24
 Identities = 76/171 (44%), Positives = 93/171 (54%), Gaps = 6/171 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAV-----LIDMSTIPPAESRALAARVAAVMGGGDD 189
           +ITMLP+ A V +    L P   +  V     L+D STI PA  R LAA   A       
Sbjct: 60  VITMLPAAAHVRSAY--LGPEGVLAGVRPGVPLVDSSTIDPATVRELAAAAEA------- 110

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGA 366
            G +     + DAPVSGGT  A AGTLT +VG      A V P+L+ MGR  VH G  G 
Sbjct: 111 HGNA-----LADAPVSGGTVGAQAGTLTFMVGATEALFAQVRPVLAGMGRNLVHCGGTGT 165

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
           GQV K  NNL+LG SM  V+EA AL    G+     A ++ TS+GRCWA+D
Sbjct: 166 GQVAKICNNLILGISMIGVSEAMALGVKLGIDANVLAGIVNTSTGRCWASD 216

[98][TOP]
>UniRef100_A9BZA5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Delftia acidovorans
           SPH-1 RepID=A9BZA5_DELAS
          Length = 287

 Score =  114 bits (285), Expect = 4e-24
 Identities = 71/161 (44%), Positives = 93/161 (57%), Gaps = 1/161 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           + TMLP +  V A +  LAP  P GA +IDMS+  P  +RALA  +           G  
Sbjct: 62  VFTMLPDSRIVDAVVGELAPHLPPGACIIDMSSADPNRTRALAGLL-----------GER 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
           G + +LDAPVSGG   A AGTL+I+VGG +D +A   PLL  MG+ + HVG  GAG  +K
Sbjct: 111 G-IGLLDAPVSGGVKRAIAGTLSIMVGGDADLLAQHLPLLQRMGQAITHVGPVGAGHALK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGR 504
           A NN V  A++ A AEA    AA G+ P T   V+  S+G+
Sbjct: 170 ALNNYVSAAALIATAEAIHAGAAFGIAPATIVDVINASTGK 210

[99][TOP]
>UniRef100_A4WS72 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacter sphaeroides
           ATCC 17025 RepID=A4WS72_RHOS5
          Length = 290

 Score =  114 bits (285), Expect = 4e-24
 Identities = 70/168 (41%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           + TMLP+   +      L P    GAVL D ST+    +R +AA+  A   G        
Sbjct: 55  VFTMLPNGQILRTVADELVPAMAAGAVLCDCSTVDVQSAREVAAQAEAAGLGA------- 107

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AAAGTLT +VGG+  + A V PL  IMG + VH G  GAGQ  K
Sbjct: 108 -----LDAPVSGGVGGAAAGTLTFMVGGSDAAFATVRPLFEIMGQKAVHCGGPGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[100][TOP]
>UniRef100_B5GAJ6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces sp. SPB74
           RepID=B5GAJ6_9ACTO
          Length = 666

 Score =  114 bits (285), Expect = 4e-24
 Identities = 69/167 (41%), Positives = 90/167 (53%), Gaps = 1/167 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +I+MLP+   V      +   A  G + +D STI  A++RA+ A               G
Sbjct: 429 VISMLPAGRHVLGLYEDVLGAARPGTLFVDCSTIDVADARAVHALA------------EG 476

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  LDAPVSGG   A AGTLT +VGG     A   PLL +MG+  VH GA GAGQ  K
Sbjct: 477 RGMRCLDAPVSGGVVGAEAGTLTFMVGGGEAEFAEALPLLDVMGKKAVHCGAAGAGQAAK 536

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
             NN++LG SM AV+EA  LA + G+       V +T+SG+CWA  V
Sbjct: 537 ICNNMILGVSMIAVSEAFVLAESLGLSHQALYDVASTASGQCWALSV 583

[101][TOP]
>UniRef100_Q134G6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris BisB5 RepID=Q134G6_RHOPS
          Length = 295

 Score =  114 bits (284), Expect = 6e-24
 Identities = 70/168 (41%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V A  + + P    GA++ID STI   ES   A  +AA  G         
Sbjct: 61  VVTMLPAGKHVLAVWNEILPHVAKGALIIDCSTID-VESAVQAHALAAKCGAAS------ 113

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                +DAPVSGGT  A A TLT + GG+  + AA  P+L  MG+  VH G  GAGQ  K
Sbjct: 114 -----IDAPVSGGTGGAKAATLTFMAGGSEAAFAAAKPVLEQMGKKIVHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM AV+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIAVSEAFTLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[102][TOP]
>UniRef100_C3K209 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas fluorescens
           SBW25 RepID=C3K209_PSEFS
          Length = 295

 Score =  114 bits (284), Expect = 6e-24
 Identities = 73/172 (42%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V +       +      G   +D STI P   R +AA  AA  G      
Sbjct: 60  VITMLPAAAHVRSVWLNDDGVLAGIGKGVPAVDCSTIDPQTIRDIAA-AAAKQG------ 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                V V DAPVSGGT  AAAGTLT +VG   +  A + P+L+ MGR  VH G  G GQ
Sbjct: 113 -----VVVADAPVSGGTGGAAAGTLTFMVGATPELFATLQPVLAQMGRNIVHCGDVGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMVGVSEAMALGDALGIDTQVLAGIINSSTGRCWSSDTYN 219

[103][TOP]
>UniRef100_A4YSR2 Putative 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bradyrhizobium
           sp. ORS278 RepID=A4YSR2_BRASO
          Length = 296

 Score =  114 bits (284), Expect = 6e-24
 Identities = 71/169 (42%), Positives = 91/169 (53%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A++TMLP+   V A  + + P    GA++ID STI   ES   A  +AA  G        
Sbjct: 60  AVVTMLPAGKHVLAVWNEVVPAMSKGALIIDSSTID-VESARSAHALAAKHG-------- 110

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVV 378
              +  +DAPVSGGT  A A TLT + GG   + AA  P+L  MG+  VH G  GAGQ  
Sbjct: 111 ---IAAVDAPVSGGTGGAKAATLTFMCGGEEGAFAAAKPILETMGKKIVHCGGAGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM AV EA AL    G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIAVGEAFALGEKLGLSHQALFDVASTSSGQCWSLTSY 216

[104][TOP]
>UniRef100_UPI0000F2F408 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter baumannii
           ATCC 17978 RepID=UPI0000F2F408
          Length = 234

 Score =  113 bits (283), Expect = 7e-24
 Identities = 66/143 (46%), Positives = 83/143 (58%), Gaps = 1/143 (0%)
 Frame = +1

Query: 97  GAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSGGRVHVLDAPVSGGTAAAAAGTLTI 276
           G++ ID STI P   + +AA   +              + + DAPVSGGT  A AGTLT 
Sbjct: 25  GSLCIDSSTIDPQTIKDIAAVAHSK------------NIKICDAPVSGGTIGAQAGTLTF 72

Query: 277 IVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVKAANNLVLGASMAAVAEATALAAAA 453
           +VG    +   V P+LS MG+  VH G  GAGQ+ K  NNL+LG SMAAVAE  AL    
Sbjct: 73  MVGADEQTFNEVKPVLSHMGKNIVHCGDVGAGQIAKICNNLILGISMAAVAEGMALGVKL 132

Query: 454 GVPPVTTAVVLATSSGRCWAADV 522
           G+ P   A V+ TSSGRCW++DV
Sbjct: 133 GIDPQALAGVINTSSGRCWSSDV 155

[105][TOP]
>UniRef100_Q7WA36 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bordetella parapertussis
           RepID=Q7WA36_BORPA
          Length = 297

 Score =  113 bits (283), Expect = 7e-24
 Identities = 68/171 (39%), Positives = 99/171 (57%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGA--VLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           +I+MLP++  V          A +GA  ++I+ STI P  +R +AA   A          
Sbjct: 61  VISMLPASKHVEGLYLGQDLLASIGASALVIECSTIAPDSARKVAAAAQA---------- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
               + ++DAPVSGGT  AAAGTLT IVGG + ++    P+L+ MG+ + H G  GAGQV
Sbjct: 111 --RGIAMIDAPVSGGTGGAAAGTLTFIVGGEAPALERARPVLASMGKNIFHAGGAGAGQV 168

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            K  NN++LG  MA  +EA AL  A G+ P   + +++ SSGR WA ++Y+
Sbjct: 169 AKICNNMLLGILMAGTSEALALGVANGLDPKVLSDIISKSSGRNWATELYN 219

[106][TOP]
>UniRef100_Q7VYA3 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Bordetella
           RepID=Q7VYA3_BORPE
          Length = 297

 Score =  113 bits (283), Expect = 7e-24
 Identities = 68/171 (39%), Positives = 99/171 (57%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGA--VLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           +I+MLP++  V          A +GA  ++I+ STI P  +R +AA   A          
Sbjct: 61  VISMLPASKHVEGLYLGQDLLASIGASALVIECSTIAPDSARKVAAAAQA---------- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
               + ++DAPVSGGT  AAAGTLT IVGG + ++    P+L+ MG+ + H G  GAGQV
Sbjct: 111 --RGIAMIDAPVSGGTGGAAAGTLTFIVGGEAPALERARPVLASMGKNIFHAGGAGAGQV 168

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            K  NN++LG  MA  +EA AL  A G+ P   + +++ SSGR WA ++Y+
Sbjct: 169 AKICNNMLLGILMAGTSEALALGVANGLDPKVLSDIISKSSGRNWATELYN 219

[107][TOP]
>UniRef100_UPI00016ACA67 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia
           pseudomallei 14 RepID=UPI00016ACA67
          Length = 186

 Score =  113 bits (282), Expect = 9e-24
 Identities = 57/104 (54%), Positives = 72/104 (69%), Gaps = 1/104 (0%)
 Frame = +1

Query: 220 LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVKAANNL 396
           +DAPVSGGT  AAAGTLT +VGG     A   P+L+ MG+  VH GA G GQV K  NNL
Sbjct: 4   VDAPVSGGTGGAAAGTLTFMVGGDDADYARAKPVLAAMGKNIVHCGATGMGQVAKVCNNL 63

Query: 397 VLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           VLG +MA V+EA AL A+ G+ P   A ++ TS+GRCW++D Y+
Sbjct: 64  VLGITMAGVSEAMALGASLGIDPKVLAGIINTSTGRCWSSDTYN 107

[108][TOP]
>UniRef100_Q4KIP8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas fluorescens
           Pf-5 RepID=Q4KIP8_PSEF5
          Length = 295

 Score =  113 bits (282), Expect = 9e-24
 Identities = 73/172 (42%), Positives = 100/172 (58%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAAT-LHALAPRAPVGAVL--IDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V +  L      A +G  +  +D STI P  +R +AA  AA  G      
Sbjct: 60  VITMLPAAAHVRSVWLGEDGVLAGIGRGIPAVDCSTIDPQTAREVAA-AAAKQG------ 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                V + DAPVSGGT  A AGTLT +VG +++  A + P+L+ MGR  VH G  G GQ
Sbjct: 113 -----VAMADAPVSGGTGGAQAGTLTFMVGASAELFATLQPVLAQMGRNIVHCGEVGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+LG SM  V+EA AL  A G+     A ++ +S+GRCW++D Y+
Sbjct: 168 IAKICNNLLLGISMIGVSEAMALGDALGIDTQVLAGIINSSTGRCWSSDTYN 219

[109][TOP]
>UniRef100_UPI00018650E0 hypothetical protein BRAFLDRAFT_125003 n=1 Tax=Branchiostoma
           floridae RepID=UPI00018650E0
          Length = 287

 Score =  112 bits (281), Expect = 1e-23
 Identities = 71/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  V       H +  +   G++LID STI PA S+ +A  VAA  GG     
Sbjct: 50  IITMLPSSPNVHEVYCGEHGILSKVKAGSLLIDSSTIDPAVSKEMA-EVAAKKGGV---- 104

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                   +DAPVSGG  AAAA TLT +VGG  +   A   LL  MG+ V + G  G+GQ
Sbjct: 105 -------YMDAPVSGGIKAAAAATLTFMVGGKQEEFEAAKELLQFMGKNVVYCGDVGSGQ 157

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            VK  NN++L   M   +E   L    G+ P   A V+  S+GRCWA+D Y+
Sbjct: 158 AVKICNNMLLAIEMIGTSETMNLGMRLGLDPKLLASVINMSTGRCWASDTYN 209

[110][TOP]
>UniRef100_Q4ZYL2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas syringae pv.
           syringae B728a RepID=Q4ZYL2_PSEU2
          Length = 295

 Score =  112 bits (281), Expect = 1e-23
 Identities = 73/176 (41%), Positives = 98/176 (55%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAAT-------LHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +ITMLP+ A V +        L  ++P  P     +D STI P   R +AA VAA  G  
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLKGISPGVPA----VDCSTIDPQTIRDIAA-VAAQQG-- 112

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGAC 360
                    V + DAPVSGGT  A AGTLT +VGG++   A + P+L  MGR  VH G  
Sbjct: 113 ---------VVLGDAPVSGGTGGAQAGTLTFMVGGSAGHFAVLKPVLEQMGRNIVHCGDV 163

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G GQ+ K  NN++L  SM  VAE+ AL  A G+     A ++ TS+GRCW+++ Y+
Sbjct: 164 GTGQIAKICNNMLLAISMIGVAESMALGNALGIDTEVLAGIINTSTGRCWSSEAYN 219

[111][TOP]
>UniRef100_Q4FTA1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Psychrobacter arcticus
           273-4 RepID=Q4FTA1_PSYA2
          Length = 321

 Score =  112 bits (281), Expect = 1e-23
 Identities = 70/175 (40%), Positives = 97/175 (55%), Gaps = 7/175 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +I+MLP+   V +          L    P G ++ID STI  A++R +A   A+ +G   
Sbjct: 82  VISMLPAGKHVHSVYLGEDRSKGLLADLPKGTLVIDSSTIAAADARKVA-EAASKLG--- 137

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
                   +  LDAPVSGGT  A AGTLT IVGG+ D+ A   P+L++MG+ + H G  G
Sbjct: 138 --------IDFLDAPVSGGTGGAIAGTLTFIVGGSDDAFAKAEPILAVMGKNIFHAGEHG 189

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           AGQV K  NN++LG  MA  AEA  L    G+ P   + ++  SSGR W  +VY+
Sbjct: 190 AGQVAKICNNMLLGILMAGTAEAINLGVKNGLDPKVLSDIMLQSSGRNWTLEVYN 244

[112][TOP]
>UniRef100_Q2L112 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bordetella avium 197N
           RepID=Q2L112_BORA1
          Length = 294

 Score =  112 bits (281), Expect = 1e-23
 Identities = 72/171 (42%), Positives = 99/171 (57%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL--HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           +ITMLP++  V        L  +   GA++ID STI P  +R +AA  AA   G      
Sbjct: 61  VITMLPASKHVEHLYLEQDLLGKIKAGALVIDCSTIAPDSARKVAA--AATARG------ 112

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
               + ++DAPVSGGT  A AGTLT IVGGA+  +    P+L  MG+ + H G  G+GQV
Sbjct: 113 ----LEMIDAPVSGGTGGAVAGTLTFIVGGAA--LERARPVLEKMGKNIFHAGEAGSGQV 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            K  NN++LG  MA  +EA AL  A G+ P   + ++A SSGR WA ++Y+
Sbjct: 167 AKICNNMLLGILMAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYN 217

[113][TOP]
>UniRef100_Q1GNL2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Sphingopyxis alaskensis
           RepID=Q1GNL2_SPHAL
          Length = 291

 Score =  112 bits (281), Expect = 1e-23
 Identities = 70/170 (41%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATL-HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           A++TMLP+   VA    + + P A  G +L+D STI  A +R+    + A    G     
Sbjct: 59  AVVTMLPAGTHVAGVYENDVFPNAAPGTLLLDCSTIDVATARS---NIEAATAKG----- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
               +  +DAPVSGG AAA AGTLT +VGG  +  A   P+L+ MG+ V H G  GAGQ 
Sbjct: 111 ----LVAVDAPVSGGIAAANAGTLTFMVGGTEEGFARAQPILAKMGKAVIHAGDAGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LGASM A  E  ALA   G+ P     + + SSG+CW+   Y
Sbjct: 167 AKICNNMLLGASMVATCETLALAQKLGLDPQKFFDIASVSSGQCWSLTSY 216

[114][TOP]
>UniRef100_C1BAP8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodococcus opacus B4
           RepID=C1BAP8_RHOOB
          Length = 298

 Score =  112 bits (281), Expect = 1e-23
 Identities = 72/164 (43%), Positives = 89/164 (54%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLPS   V      L P A  G + +D STI  A++RA AA +A   G         
Sbjct: 61  IITMLPSGKHVLDVYADLVPAAQPGTLFLDCSTIDVADARA-AAELAVAAGHS------- 112

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                +DAPVSGGT  A  GTLT +VGG +D+V      L  MG R V  G  GAGQ  K
Sbjct: 113 ----AVDAPVSGGTVGADGGTLTFMVGGPADAVDRAATFLDAMGSRIVRCGDAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM AV+EA AL A  G+       V +T+SG+CWA
Sbjct: 169 ICNNMILGISMIAVSEAFALGAKLGLTDQALFDVSSTASGQCWA 212

[115][TOP]
>UniRef100_A4XS20 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas mendocina
           ymp RepID=A4XS20_PSEMY
          Length = 294

 Score =  112 bits (281), Expect = 1e-23
 Identities = 72/172 (41%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         L  R P G ++I+ STI P  +R + A  AA   G     
Sbjct: 61  VISMLPASRHVEGLYLGEDGLLARLPAGTLVIECSTIAPESARKVHA--AARERG----- 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                V +LDAPVSGGTA AAAGTLT +VGG + ++    P+L+ MGR + H G  GAGQ
Sbjct: 114 -----VALLDAPVSGGTAGAAAGTLTFMVGGEAQALEKARPILAAMGRNIFHAGPDGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN VL   M A AEA A+  A G+ P   A ++  SSG  W  + Y+
Sbjct: 169 VAKVCNNQVLAVQMIATAEAMAMGVANGLEPAVLAEIMRQSSGGNWTLEKYN 220

[116][TOP]
>UniRef100_B5WMS7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia sp. H160
           RepID=B5WMS7_9BURK
          Length = 299

 Score =  112 bits (281), Expect = 1e-23
 Identities = 70/169 (41%), Positives = 95/169 (56%), Gaps = 4/169 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP+   V + L A   +         +ID STI P  +R +A R+A + G      
Sbjct: 60  VVTMLPAAVHVRSVLTADDGVFAGCGDSVTVIDSSTIDPTTARDMA-RMAEIRG------ 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                +  +DAPVSGGT  A AGTLT +VGG S+    V P+L  MG+  VH G  G GQ
Sbjct: 113 -----LTFVDAPVSGGTGGAQAGTLTFMVGGTSEQYDRVVPVLKGMGKNIVHCGGVGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
           V K  NNLVLG +MA  AEA AL  + G+ P   A ++ TS+GR W+++
Sbjct: 168 VAKICNNLVLGVTMAGTAEAMALGESLGIDPQVLAGIMNTSTGRSWSSE 216

[117][TOP]
>UniRef100_C5LYJ6 3-hydroxyisobutyrate dehydrogenase, putative n=1 Tax=Perkinsus
           marinus ATCC 50983 RepID=C5LYJ6_9ALVE
          Length = 316

 Score =  112 bits (281), Expect = 1e-23
 Identities = 71/173 (41%), Positives = 95/173 (54%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVA----ATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +I+MLP T  V     AT   +       + LID STI P  ++ +  +           
Sbjct: 80  IISMLPGTRDVVELYTATNGGILSLLEKSSFLIDCSTIDPIAAQHVIRKAQE-------- 131

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGAS-DSVAAVTPLLSIMGRPVHVGACGAG 369
              G R+  +DAPVSGG  AA AGTLT +VG  + + + A T +LS MG P H G  G G
Sbjct: 132 --QGHRM--VDAPVSGGVPAAKAGTLTFMVGADTPEDLKAATEILSAMGNPKHCGGTGLG 187

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q VK +NNL+L ASM  VAE   LA + GV P   A ++ TS+GRCW++D Y+
Sbjct: 188 QAVKVSNNLILAASMLGVAEGFRLAKSLGVDPKVFAEIVNTSTGRCWSSDTYN 240

[118][TOP]
>UniRef100_Q99L13 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Mus
           musculus RepID=3HIDH_MOUSE
          Length = 335

 Score =  112 bits (281), Expect = 1e-23
 Identities = 71/172 (41%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPST---AAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+     V +  + +  +   G++LID STI P+ S+ LA  V  +        
Sbjct: 98  IITMLPSSMNAVEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKM-------- 149

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 150 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLECMGSNVVYCGAVGTGQ 205

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L   +G+ P   A +L  SSGRCW++D Y+
Sbjct: 206 SAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYN 257

[119][TOP]
>UniRef100_Q2GA17 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Novosphingobium
           aromaticivorans DSM 12444 RepID=Q2GA17_NOVAD
          Length = 289

 Score =  112 bits (280), Expect = 2e-23
 Identities = 70/170 (41%), Positives = 99/170 (58%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHA-LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           A+++MLP+ A V +   A +  +AP  A+L+D STI  A +R +A+              
Sbjct: 59  AVVSMLPNGAIVKSVYAADVIGQAPTSALLLDCSTIDVATAREVASAA-----------D 107

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
           + G V V DAPVSGG AAA  GTLT +VGG+ ++ A   P+L+ MG+ V H GA GAGQ 
Sbjct: 108 TAGYVMV-DAPVSGGIAAANGGTLTFMVGGSDEAFARAEPILAAMGKAVIHAGASGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LGASM A  E  A+A   G+   T   + + +SG+CW+   Y
Sbjct: 167 AKICNNMLLGASMVATCETFAMAEKLGLDLQTFYDISSKASGQCWSMTSY 216

[120][TOP]
>UniRef100_Q2CA17 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Oceanicola granulosus
           HTCC2516 RepID=Q2CA17_9RHOB
          Length = 290

 Score =  112 bits (280), Expect = 2e-23
 Identities = 71/168 (42%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +I MLP   AV      +      GAVL+D STI  A +R +A             GGS 
Sbjct: 55  VILMLPDGGAVRDVAGRILDGMSAGAVLVDCSTIDVATAREVARL-----------GGSH 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
           G +  LDAPV+GGT  AA G LT + GG +D+ A V PL   MG R VH GA G GQ  +
Sbjct: 104 G-IACLDAPVTGGTTGAAEGGLTFLAGGDTDAFARVRPLFETMGSRAVHCGAAGNGQAAR 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 LCNNMILGATMIATCEAMALAEKLGLGQKALFNVVSTSSGSSWSMNTY 210

[121][TOP]
>UniRef100_D0CRK5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Silicibacter
           lacuscaerulensis ITI-1157 RepID=D0CRK5_9RHOB
          Length = 290

 Score =  112 bits (280), Expect = 2e-23
 Identities = 69/169 (40%), Positives = 92/169 (54%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   + A    + P    GAV ID ST+    +RA+A +         +  G 
Sbjct: 54  AVITMLPNGDILRAVADQIIPHMEKGAVFIDCSTVDVDSARAVAEQA--------EQAG- 104

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVV 378
              +  +DAPVSGG   AAAGTLT + GG+  + A   PL  IMG + VH GA GAGQ  
Sbjct: 105 ---LLAVDAPVSGGIGGAAAGTLTFMAGGSDAAFAKAAPLFEIMGQKAVHCGAAGAGQAA 161

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 162 KICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[122][TOP]
>UniRef100_Q212Q3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris BisB18 RepID=Q212Q3_RHOPB
          Length = 295

 Score =  112 bits (279), Expect = 2e-23
 Identities = 71/168 (42%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V A    + PR   GA++ID STI    S  + A  AA            
Sbjct: 61  VVTMLPAGNHVLAVWDEILPRIAKGALIIDCSTIDVGSS--IRAHAAAAKH--------- 109

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             V  +DAPVSGGT  A A TLT + GGA  +  A  P+L +MG+  VH G  GAGQ  K
Sbjct: 110 -EVASVDAPVSGGTGGAKAATLTFMAGGAQVAFDAAKPVLELMGKKIVHCGGPGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM AV+EA ALA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIAVSEAFALAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[123][TOP]
>UniRef100_B2S6F0 MmsB, 3-hydroxyisobutyrate dehydrogenase n=9 Tax=Brucella abortus
           RepID=B2S6F0_BRUA1
          Length = 296

 Score =  112 bits (279), Expect = 2e-23
 Identities = 70/170 (41%), Positives = 96/170 (56%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI  A+S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-ADSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT++ GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTVMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[124][TOP]
>UniRef100_C7NLU6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Kytococcus sedentarius
           DSM 20547 RepID=C7NLU6_KYTSD
          Length = 296

 Score =  111 bits (278), Expect = 3e-23
 Identities = 74/168 (44%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVL-IDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           A+ITMLPS   V +    + P A    VL ID STI    +R  A  V        D G 
Sbjct: 59  AVITMLPSGPIVLSCYEEIIPAATGEDVLFIDSSTIDVESARKAADMVR-------DAGH 111

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
           S      +DAPVSGG   + AGTLT +VGG   + A   PLL +MGR  VH G  G GQ 
Sbjct: 112 SS-----IDAPVSGGVVGSEAGTLTFMVGGTEQAFARAEPLLEVMGRKIVHCGDAGNGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
            K  NN++LG  M AV+EA  L    G+ P     V +TSSGRCWA D
Sbjct: 167 AKICNNMLLGVQMIAVSEAFVLGEKLGLDPQAFFDVASTSSGRCWALD 214

[125][TOP]
>UniRef100_UPI00005A2C17 PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase,
           mitochondrial precursor (HIBADH) isoform 1 n=1 Tax=Canis
           lupus familiaris RepID=UPI00005A2C17
          Length = 336

 Score =  111 bits (277), Expect = 4e-23
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 99  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM-------- 150

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 151 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 206

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 207 AAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 258

[126][TOP]
>UniRef100_UPI0000EB202D 3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC
           1.1.1.31) (HIBADH). n=1 Tax=Canis lupus familiaris
           RepID=UPI0000EB202D
          Length = 347

 Score =  111 bits (277), Expect = 4e-23
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 110 IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM-------- 161

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 162 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 217

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 218 AAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 269

[127][TOP]
>UniRef100_A3JS92 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacterales
           bacterium HTCC2150 RepID=A3JS92_9RHOB
          Length = 290

 Score =  111 bits (277), Expect = 4e-23
 Identities = 66/168 (39%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           LITMLP+ A + +  + + P    GA  +D ST+    +RA+A            D  + 
Sbjct: 55  LITMLPNGAILRSVANEVMPALKSGAAFLDCSTVDVESARAVA------------DQANA 102

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             V  LDAPVSGG   A AGTLT +VGG+    +   PL  IMG + VH G  G GQ  K
Sbjct: 103 ADVLALDAPVSGGIGGAVAGTLTFMVGGSDAGFSLAKPLFDIMGQKSVHCGPSGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M A  E+ ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGATMVATCESIALADKLGLDRQALFDVVSTSSGSSWSMNTY 210

[128][TOP]
>UniRef100_B9TM46 3-hydroxyisobutyrate dehydrogenase, putative (Fragment) n=1
           Tax=Ricinus communis RepID=B9TM46_RICCO
          Length = 202

 Score =  111 bits (277), Expect = 4e-23
 Identities = 67/147 (45%), Positives = 85/147 (57%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +I+ML +   V   L A  P  P  A+ IDMS+   AE++A  A++ A           G
Sbjct: 50  VISMLEAGPIVQQVLQAALPALPANALWIDMSSTQQAEAQAFHAQLTA----------QG 99

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPVHVGACGAGQVVKA 384
            R   +DAPVSGG   AAAGTL I+ GG++D  A   P+LS MGRP  VG  GAGQV K 
Sbjct: 100 QRF--IDAPVSGGVGGAAAGTLAIMAGGSADDFADAEPVLSAMGRPTLVGPAGAGQVAKL 157

Query: 385 ANNLVLGASMAAVAEATALAAAAGVPP 465
            N L++GA++  VAEA  LA AAG  P
Sbjct: 158 CNQLIVGATINIVAEAMLLAQAAGADP 184

[129][TOP]
>UniRef100_C9JHR2 Putative uncharacterized protein HIBADH (Fragment) n=1 Tax=Homo
           sapiens RepID=C9JHR2_HUMAN
          Length = 206

 Score =  111 bits (277), Expect = 4e-23
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 42  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM-------- 93

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 94  ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 149

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 150 AAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 201

[130][TOP]
>UniRef100_Q5R5E7 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Pongo
           abelii RepID=3HIDH_PONAB
          Length = 336

 Score =  111 bits (277), Expect = 4e-23
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 99  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM-------- 150

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 151 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 206

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 207 AAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 258

[131][TOP]
>UniRef100_P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=3 Tax=Homininae
           RepID=3HIDH_HUMAN
          Length = 336

 Score =  111 bits (277), Expect = 4e-23
 Identities = 73/172 (42%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 99  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM-------- 150

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 151 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 206

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 207 AAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 258

[132][TOP]
>UniRef100_Q5LRB6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ruegeria pomeroyi
           RepID=Q5LRB6_SILPO
          Length = 290

 Score =  110 bits (276), Expect = 5e-23
 Identities = 68/168 (40%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   + A    + P    GA L+D ST+    +RA+AA           D  + 
Sbjct: 55  VVTMLPNGQILRAVAAEVIPAMTAGAALVDCSTVDVDSARAVAA-----------DAEAA 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
           G + V DAPVSGG   AAAGTLT + GG+  +     PL  IMG + VH GA GAGQ  K
Sbjct: 104 GLLAV-DAPVSGGIGGAAAGTLTFMAGGSDAAFEKAKPLFDIMGQKAVHCGAAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W  + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWTMNAY 210

[133][TOP]
>UniRef100_B0CHA8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Brucella suis ATCC 23445
           RepID=B0CHA8_BRUSI
          Length = 296

 Score =  110 bits (276), Expect = 5e-23
 Identities = 70/170 (41%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ D+     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEDAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[134][TOP]
>UniRef100_B9Z556 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Lutiella nitroferrum
           2002 RepID=B9Z556_9NEIS
          Length = 295

 Score =  110 bits (276), Expect = 5e-23
 Identities = 70/172 (40%), Positives = 98/172 (56%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +++MLP++  V       + L  + P G ++ID STI  A + A+    AA+  G     
Sbjct: 61  VLSMLPASHHVEGLYLGENGLLAQLPKGTLVIDCSTI--AAASAIKVAEAALAAG----- 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPVHV-GACGAGQ 372
                + +LDAPVSGGTA AAAGTLT IVGG +  +    PL   MG+ V + G  GAGQ
Sbjct: 114 -----LRMLDAPVSGGTAGAAAGTLTFIVGGEAADLEQARPLFEAMGKNVFLAGGHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++LG  MA  AEA AL   +G+ P   + ++A SSGR WA ++Y+
Sbjct: 169 SAKICNNMMLGILMAGTAEALALGVKSGLDPKVLSEIMAKSSGRNWALELYN 220

[135][TOP]
>UniRef100_D0B8V2 MmsB family protein n=2 Tax=Brucella melitensis RepID=D0B8V2_BRUME
          Length = 296

 Score =  110 bits (275), Expect = 6e-23
 Identities = 69/170 (40%), Positives = 95/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT++ GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTVMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[136][TOP]
>UniRef100_C1DAN5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Laribacter hongkongensis
           HLHK9 RepID=C1DAN5_LARHH
          Length = 304

 Score =  110 bits (275), Expect = 6e-23
 Identities = 68/175 (38%), Positives = 98/175 (56%), Gaps = 7/175 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +++MLP++  V            L    P G ++ID STI P  ++ +AA  AA      
Sbjct: 61  VVSMLPASRHVEGLYLGDEGESGLLALLPAGTLVIDCSTISPHSAQKVAAAAAA------ 114

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
               SG  + ++DAPVSGGTA AAA TLT +VGG++ ++    PLL+ MG+ + H G  G
Sbjct: 115 ----SG--IDMIDAPVSGGTAGAAAATLTFMVGGSNAALDRAQPLLAAMGKNIFHAGGSG 168

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           AGQV K  NN++LG  M AV+EA AL A  G+     + ++  SSG  W  + Y+
Sbjct: 169 AGQVAKVCNNMILGVQMIAVSEALALGARQGLDVQVLSGIIDQSSGANWVTERYN 223

[137][TOP]
>UniRef100_C0RJS6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Brucella melitensis ATCC
           23457 RepID=C0RJS6_BRUMB
          Length = 296

 Score =  110 bits (275), Expect = 6e-23
 Identities = 69/170 (40%), Positives = 95/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYENIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT++ GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTVMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[138][TOP]
>UniRef100_Q0FTH1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseovarius sp. HTCC2601
           RepID=Q0FTH1_9RHOB
          Length = 290

 Score =  110 bits (275), Expect = 6e-23
 Identities = 67/168 (39%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + +    + P    GAVL+D ST+    +RA+A + A        + G G
Sbjct: 55  VITMLPNGQILRSVAAEVIPAMSPGAVLLDCSTVDVESARAVADQAA--------EAGLG 106

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   A+ GTLT +VGG+ ++ A   PL  IMG + VH G  G GQ  K
Sbjct: 107 A----LDAPVSGGIGGASGGTLTFMVGGSDEAFAKARPLFDIMGQKAVHCGPSGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLSREAMFDVVSTSSGYSWSMNAY 210

[139][TOP]
>UniRef100_A6NVP0 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6NVP0_9BACE
          Length = 306

 Score =  110 bits (275), Expect = 6e-23
 Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 4/169 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I  LP+   V  T+   + +      G V+IDMS++ P  ++A+A + A       + G
Sbjct: 65  IICSLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAA-------EKG 117

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +H +DAPVSGG + AAAGTLTI+VG   ++   V P+  ++G+ + HVG  G G 
Sbjct: 118 -----IHYIDAPVSGGVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGD 172

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
            +K  NNL+LG +MAA+AEA  L    G+   T   V++ SSGR +A D
Sbjct: 173 AIKMVNNLLLGCNMAALAEALTLGVKCGLSVETMKEVISVSSGRSYALD 221

[140][TOP]
>UniRef100_P29266 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Rattus
           norvegicus RepID=3HIDH_RAT
          Length = 335

 Score =  110 bits (275), Expect = 6e-23
 Identities = 70/172 (40%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA---AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+     V +  + +  +   G++LID STI P+ S+ LA  V  +        
Sbjct: 98  IITMLPSSMNSIEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKM-------- 149

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  +  AA   LL  MG  V + GA G+GQ
Sbjct: 150 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVENEFAAAQELLGCMGSNVLYCGAVGSGQ 205

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AEA  L   +G+ P   A +L  SSGRCW++D Y+
Sbjct: 206 SAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYN 257

[141][TOP]
>UniRef100_UPI0001AF5D5F 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas syringae pv.
           oryzae str. 1_6 RepID=UPI0001AF5D5F
          Length = 295

 Score =  110 bits (274), Expect = 8e-23
 Identities = 69/176 (39%), Positives = 97/176 (55%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAAT-------LHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +ITMLP+ A V +        L  ++P  P     +D STI P   R +A  +A   G  
Sbjct: 60  VITMLPAAAHVRSVYLNDDGVLKGISPGVPA----VDCSTIDPQTIRDIAG-IATQQG-- 112

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGAC 360
                    V + DAPVSGGT  A AGTLT +VGG+    A + P+L++MGR  VH G  
Sbjct: 113 ---------VILGDAPVSGGTGGAQAGTLTFMVGGSVQHFATLKPVLALMGRNIVHCGDV 163

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G GQ+ K  NN++L  SM  V+E+ AL  A G+     A ++ TS+GRCW+++ Y+
Sbjct: 164 GTGQIAKICNNMLLAISMIGVSESMALGNALGIDTEVLASIINTSTGRCWSSEAYN 219

[142][TOP]
>UniRef100_UPI0001AED875 putative 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces
           roseosporus NRRL 11379 RepID=UPI0001AED875
          Length = 307

 Score =  110 bits (274), Expect = 8e-23
 Identities = 72/169 (42%), Positives = 91/169 (53%), Gaps = 3/169 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL--HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           +ITMLP+   V +      L   A  G + +D STI  A+SRA  A  AA   G      
Sbjct: 62  VITMLPAGRHVLSLYGPEGLLAAARPGTLFVDCSTIDVADSRA--AHAAASEAGHRS--- 116

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
                  LDAPVSGG   A AGTLT + GG   + A   PLL++MG+  VH GA GAGQ 
Sbjct: 117 -------LDAPVSGGVVGAEAGTLTFMAGGEEAAFAEAEPLLTVMGKKAVHCGAAGAGQA 169

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
            K  NN++LG SM AV+EA  LA + G+       V + +SG+CWA  V
Sbjct: 170 AKICNNMILGVSMIAVSEAFVLAESLGLSDQALFDVASAASGQCWALTV 218

[143][TOP]
>UniRef100_Q46NP2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ralstonia eutropha
           JMP134 RepID=Q46NP2_RALEJ
          Length = 293

 Score =  110 bits (274), Expect = 8e-23
 Identities = 64/172 (37%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+ A V + +     +      G+++ID ST  P  +R L + +A   G      
Sbjct: 60  VITMLPTPAIVRSVIGGPDGIIVHTKPGSLIIDCSTSDPQMARELES-IAQAHGNS---- 114

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                  ++DAPVSGG   A A TLT +VGG  ++  A  P+L+ MG+  V  G+ G+GQ
Sbjct: 115 -------MIDAPVSGGVPGAQAATLTFMVGGTEEAFVAAQPILAAMGKNIVRCGSAGSGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NNL+LG S  AV+E+  L  + G+ P   A ++ TSSG CW ++VY+
Sbjct: 168 AAKICNNLLLGVSTVAVSESMCLGVSLGLSPDVLAAIINTSSGHCWVSEVYN 219

[144][TOP]
>UniRef100_Q1QAL1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Psychrobacter
           cryohalolentis K5 RepID=Q1QAL1_PSYCK
          Length = 321

 Score =  110 bits (274), Expect = 8e-23
 Identities = 70/175 (40%), Positives = 96/175 (54%), Gaps = 7/175 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +I+MLP+   V +          L    P G ++ID STI  A++R +A  VA+ +G   
Sbjct: 82  IISMLPAGKHVHSVYLGEGSSDGLLVDLPKGTLVIDSSTIAAADARKVA-EVASKLG--- 137

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
                   +  LDAPVSGGT  A AGTLT IVGG   + A   P+L++MG+ + H G  G
Sbjct: 138 --------IDFLDAPVSGGTGGAIAGTLTFIVGGDDAAFAKAEPILAVMGKNIFHAGEHG 189

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           AGQV K  NN++LG  MA  AEA  L    G+ P   + ++  SSGR W  +VY+
Sbjct: 190 AGQVAKICNNMLLGILMAGTAEAINLGVKNGLDPKVLSDIMLQSSGRNWTLEVYN 244

[145][TOP]
>UniRef100_Q13LQ9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia xenovorans
           LB400 RepID=Q13LQ9_BURXL
          Length = 296

 Score =  110 bits (274), Expect = 8e-23
 Identities = 74/168 (44%), Positives = 90/168 (53%), Gaps = 7/168 (4%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           ALITMLP++A V A +         A R   GAV+IDMS+  P  SRAL   + A     
Sbjct: 62  ALITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQ---- 117

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGAC 360
                   R+  LDAPVSGG   A  GTL I+VGG +D +A   PLL  MG  V H+G  
Sbjct: 118 --------RLAYLDAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTA 169

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGR 504
           GAG   KA NN V  AS+AA  EA  +A+  G+ P     VL  S+GR
Sbjct: 170 GAGHAAKALNNYVSAASVAATVEALQIASRFGIDPQVMTDVLNASTGR 217

[146][TOP]
>UniRef100_C6RL62 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter
           radioresistens SK82 RepID=C6RL62_ACIRA
          Length = 296

 Score =  110 bits (274), Expect = 8e-23
 Identities = 70/170 (41%), Positives = 92/170 (54%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V       + +      G++ ID STI P   + +AA  A          
Sbjct: 60  VITMLPAAKHVKDVYLGENGVLAVLKAGSLCIDSSTIDPQTIKDIAASAAE--------- 110

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + + DAPVSGGT  A AGTLT +VG    +   V  +LS MG+  VH G  GAGQ
Sbjct: 111 ---REITICDAPVSGGTIGAQAGTLTFMVGTDEATFIRVKTVLSPMGKNMVHCGDVGAGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SMAAVAE  AL    G+ P   A V+ +SSGRCW+++V
Sbjct: 168 IAKICNNLILGISMAAVAEGMALGVKLGIDPQALAGVINSSSGRCWSSEV 217

[147][TOP]
>UniRef100_C6N252 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Legionella drancourtii
           LLAP12 RepID=C6N252_9GAMM
          Length = 301

 Score =  110 bits (274), Expect = 8e-23
 Identities = 69/171 (40%), Positives = 91/171 (53%), Gaps = 4/171 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITML +   V A  H    L      G++LID STI    +R L     A         
Sbjct: 59  IITMLQTGQQVLAVYHGPDGLLTMLKQGSLLIDCSTIDVNSARELHQLAHAQS------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + V+DAPVSGGTA AAAGTLT +VGG   +  A  P+L+ MG+ + H G  G+GQ
Sbjct: 112 -----IRVVDAPVSGGTAGAAAGTLTFMVGGEEAAFHAAQPILAAMGQKIIHTGVAGSGQ 166

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             K  NN++LG SM A++EA  LA    + P     V++ SSG+CWA   Y
Sbjct: 167 AAKICNNMILGISMIAISEAFVLAEQLHLSPQKLFEVVSNSSGQCWAMSKY 217

[148][TOP]
>UniRef100_B5GMB3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GMB3_STRCL
          Length = 304

 Score =  110 bits (274), Expect = 8e-23
 Identities = 68/167 (40%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V      + P A  G +L+D STI  A++R    R  AV  G        
Sbjct: 62  VITMLPAGRHVLGLYEEILPAARPGTLLVDCSTIDVADAREAHRR--AVTAG-------- 111

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  LDAPVSGG   A A TLT + GG         PLL+ MG+  VH G  GAGQ  K
Sbjct: 112 --MRALDAPVSGGVVGAEAATLTFMAGGGEAEFTEARPLLAAMGKKAVHCGGAGAGQAAK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
             NN++LG SM AV+EA  L  + G+       V +T+SG+CWA  V
Sbjct: 170 ICNNMILGVSMIAVSEAFVLGESLGLSHQALYDVASTASGQCWALTV 216

[149][TOP]
>UniRef100_A9FQT9 Transketolase n=1 Tax=Phaeobacter gallaeciensis BS107
           RepID=A9FQT9_9RHOB
          Length = 291

 Score =  110 bits (274), Expect = 8e-23
 Identities = 67/168 (39%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + A    + P    GA L+D ST+    +RA+A           D  GS 
Sbjct: 55  VITMLPNGQILRAVADDVIPAMSAGATLVDCSTVDVDSARAVA-----------DQAGSA 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             + V DAPVSGG   A+ GTLT + GG++ + AA  PL  IMG + VH G  GAGQ  K
Sbjct: 104 NLMFV-DAPVSGGIGGASGGTLTFMAGGSAAAFAAAEPLFDIMGQKAVHCGEAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M    EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGITMIGTCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[150][TOP]
>UniRef100_A3JYR4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Sagittula stellata E-37
           RepID=A3JYR4_9RHOB
          Length = 637

 Score =  110 bits (274), Expect = 8e-23
 Identities = 66/168 (39%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   +      + P    GAVL+D ST+    +RA+A++             S 
Sbjct: 402 VITMLPNGDILRGVATEIIPHMEKGAVLLDCSTVDVDSARAVASQA------------SY 449

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  LDAPVSGG   A+ GTLT +VGG  D+ A   PL  IMG + VH GA G GQ  K
Sbjct: 450 AGLMALDAPVSGGIGGASGGTLTFMVGGPDDAFAIAKPLFDIMGQKAVHCGASGNGQAAK 509

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA +LA   G+       V++TSSG  W+ + Y
Sbjct: 510 ICNNMILGVTMIATCEAFSLADKLGLSREAMFDVVSTSSGYSWSMNAY 557

[151][TOP]
>UniRef100_C3Y133 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3Y133_BRAFL
          Length = 329

 Score =  110 bits (274), Expect = 8e-23
 Identities = 70/172 (40%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  V         +  +   G++LID STI PA S+ +A  VAA  GG     
Sbjct: 92  IITMLPSSPNVQEVYCGEQGILSKVKAGSLLIDSSTIDPAVSKEMA-EVAAKKGGV---- 146

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                   +DAPVSGG  AAAA TLT +VGG  +   A   LL  MG+ V + G  G+GQ
Sbjct: 147 -------YMDAPVSGGIKAAAAATLTFMVGGKQEEFEAAKELLQFMGKNVVYCGDVGSGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            VK  NN++L   M   +E   L    G+ P   A V+  S+GRCWA+D Y+
Sbjct: 200 AVKICNNMLLAIEMIGTSETMNLGMRLGLDPKLLASVINMSTGRCWASDTYN 251

[152][TOP]
>UniRef100_Q1M5Y0 Putative 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhizobium
           leguminosarum bv. viciae 3841 RepID=Q1M5Y0_RHIL3
          Length = 293

 Score =  109 bits (273), Expect = 1e-22
 Identities = 68/170 (40%), Positives = 87/170 (51%), Gaps = 3/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDGG 198
           +ITMLP    V      +   A  G ++ID STI    SR     A+ A+ +        
Sbjct: 61  IITMLPQGRHVLTAWTDILQSAAQGTLVIDCSTIDVESSRKAHEMAKAASCLS------- 113

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
                  LDAPVSGGT  A AGTLT + GG+ D+ A   P+L  MG+  VH G  GAGQ 
Sbjct: 114 -------LDAPVSGGTGGATAGTLTFMAGGSEDAFARAKPILEAMGKKIVHCGEAGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+ + Y
Sbjct: 167 AKICNNMILGISMVGVCEAFVLAEKLGLSHQALFDVASTSSGQCWSINTY 216

[153][TOP]
>UniRef100_B2JSK9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Burkholderia phymatum
           STM815 RepID=B2JSK9_BURP8
          Length = 293

 Score =  109 bits (273), Expect = 1e-22
 Identities = 67/172 (38%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +++MLP+ A V   +     + P A  G ++ID ST  P  +  L A   AV  G     
Sbjct: 60  IVSMLPTPAIVKEVMVSPEGVIPNAREGTLVIDCSTSDPKTAVQLEA--LAVTRG----- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                ++++DAPVSGG   A AGTLT +VGG      A  P+L+ MG+ V H G  G+GQ
Sbjct: 113 -----LNLIDAPVSGGVPGAKAGTLTFMVGGTEAGFLAAKPVLTAMGQNVVHCGPPGSGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NNL+LG S  AV+E+  L    G+ P   A ++ +SSGRCW ++VY+
Sbjct: 168 AAKLCNNLLLGVSTIAVSESMCLGVRLGLDPSVLANIINSSSGRCWVSEVYN 219

[154][TOP]
>UniRef100_A7IHE0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Xanthobacter
           autotrophicus Py2 RepID=A7IHE0_XANP2
          Length = 314

 Score =  109 bits (273), Expect = 1e-22
 Identities = 73/173 (42%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDD 189
           ++TMLPS   V A       L   A  G + ID STI  A +RA   AA+ A        
Sbjct: 76  VVTMLPSGKHVVAATSGSDGLFAAARPGTLFIDSSTIDVASARAFHEAAKTA-------- 127

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGA 366
                G   V DAPVSGG   A AGTLT +VGG  D+  A  PLL +MG+  VH G  G+
Sbjct: 128 -----GHASV-DAPVSGGVGGAEAGTLTFMVGGTDDAFGAARPLLELMGKKIVHCGGAGS 181

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           GQ  K  NN++LG SM AV+EA  L    G+       V +TSSG+CW+   Y
Sbjct: 182 GQAAKICNNMILGISMIAVSEAFVLGEKLGLSHQALYDVASTSSGQCWSLTTY 234

[155][TOP]
>UniRef100_B7QRD0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ruegeria sp. R11
           RepID=B7QRD0_9RHOB
          Length = 292

 Score =  109 bits (273), Expect = 1e-22
 Identities = 67/168 (39%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + +    L P    GA L+D ST+    +RA+A + A        D G  
Sbjct: 55  VITMLPNGQILRSVAEDLVPAMTKGATLVDCSTVDVDSARAVAQQCA--------DAG-- 104

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AAAGTLT + GG+  +  A  PL  IMG + VH G  GAGQ  K
Sbjct: 105 --LQFVDAPVSGGIGGAAAGTLTFMAGGSQGAFEAAKPLFDIMGQKAVHCGDAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M    EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGITMIGTCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[156][TOP]
>UniRef100_C5LVB1 3-hydroxyisobutyrate dehydrogenase, putative n=1 Tax=Perkinsus
           marinus ATCC 50983 RepID=C5LVB1_9ALVE
          Length = 316

 Score =  109 bits (273), Expect = 1e-22
 Identities = 69/173 (39%), Positives = 93/173 (53%), Gaps = 5/173 (2%)
 Frame = +1

Query: 25  LITMLPSTAAV----AATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +I+MLP T  V     AT   +       + LID STI P  ++ +  +           
Sbjct: 80  IISMLPGTRDVEELYTATNGGILSLLEKSSFLIDCSTIDPIAAQHVIRKAQE-------- 131

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGAS-DSVAAVTPLLSIMGRPVHVGACGAG 369
              G R+  +DAPVSGG  AA AGTLT +VG  + + +   T +L  MG P H G  G G
Sbjct: 132 --QGHRM--VDAPVSGGVPAAKAGTLTFMVGADTPEDLKTATAILDAMGNPKHCGGTGLG 187

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q VK +NNL+L ASM  VAE   LA + GV P   A ++ TS+GRCW++D Y+
Sbjct: 188 QAVKVSNNLILAASMLGVAEGFRLAKSLGVDPKVFAEIVNTSTGRCWSSDTYN 240

[157][TOP]
>UniRef100_B8ICT3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8ICT3_METNO
          Length = 295

 Score =  109 bits (272), Expect = 1e-22
 Identities = 73/167 (43%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDG 195
           A++TMLPS A V +        A  G ++ID STI    +R +   AR A ++       
Sbjct: 60  AVLTMLPSGAIVRSVWREAIAAARRGVLMIDASTIDVDSAREVHGLARSAGLLS------ 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                   LDAPVSGGT  A AGTLT +VGG  DS  A  PLL  MGR  VH GA G GQ
Sbjct: 114 --------LDAPVSGGTEGATAGTLTFMVGGDPDSFDAGRPLLEAMGRRIVHCGAPGNGQ 165

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             K  NN++LG +M AV+EA  LA+  G+       V +TSSG+C+A
Sbjct: 166 AAKICNNMILGVTMIAVSEAFNLASQVGLSHQALFDVASTSSGQCYA 212

[158][TOP]
>UniRef100_A5VR79 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Brucella ovis ATCC 25840
           RepID=A5VR79_BRUO2
          Length = 296

 Score =  109 bits (272), Expect = 1e-22
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[159][TOP]
>UniRef100_C9VBA4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Brucella neotomae 5K33
           RepID=C9VBA4_BRUNE
          Length = 296

 Score =  109 bits (272), Expect = 1e-22
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[160][TOP]
>UniRef100_C7LCR1 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Brucella
           RepID=C7LCR1_BRUMC
          Length = 296

 Score =  109 bits (272), Expect = 1e-22
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[161][TOP]
>UniRef100_C0G746 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Brucella
           RepID=C0G746_9RHIZ
          Length = 310

 Score =  109 bits (272), Expect = 1e-22
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 74  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 124

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 125 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 180

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 181 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 230

[162][TOP]
>UniRef100_Q6FBV7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acinetobacter sp. ADP1
           RepID=Q6FBV7_ACIAD
          Length = 297

 Score =  108 bits (271), Expect = 2e-22
 Identities = 72/170 (42%), Positives = 95/170 (55%), Gaps = 4/170 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPV---GAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V     A      V   G++ ID STI P   + +A ++ A  G      
Sbjct: 60  VITMLPAAKHVKEIYLAEDGVFTVLKQGSICIDSSTIDPQSIKDIA-KIGAEKG------ 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                + V DAPVSGGT  A AGTLT +VG  +D    V  +LS MG+  V+ G  G+GQ
Sbjct: 113 -----IKVCDAPVSGGTIGAQAGTLTFMVGTDADLFEQVKSVLSSMGKNIVYCGEVGSGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           + K  NNL+LG SM AVAE  AL A  G+ P   A V+ +SSGRCW+++V
Sbjct: 168 IAKICNNLILGISMTAVAEGMALGAKLGIDPQILAGVINSSSGRCWSSEV 217

[163][TOP]
>UniRef100_Q07P08 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris BisA53 RepID=Q07P08_RHOP5
          Length = 295

 Score =  108 bits (271), Expect = 2e-22
 Identities = 69/169 (40%), Positives = 89/169 (52%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A++TMLP+   V A  + + P    GA++ID STI   ES   A  +A+  G G      
Sbjct: 60  AIVTMLPAGKHVLAVWNEVLPHVAKGALIIDCSTID-VESAKAAHELASKHGIGS----- 113

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVV 378
                 +DAPVSGGT  A   TLT + GG   +  A  P+L  MG+  VH GA GAGQ  
Sbjct: 114 ------IDAPVSGGTGGAKGATLTFMAGGEVLAFEAAKPVLEKMGKKIVHCGAAGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIGVCEAFTLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[164][TOP]
>UniRef100_B3QES7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris TIE-1 RepID=B3QES7_RHOPT
          Length = 295

 Score =  108 bits (271), Expect = 2e-22
 Identities = 68/168 (40%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V A  + + P A  GA++ID STI   ES   A  +AA            
Sbjct: 61  IVTMLPAGKHVLAVWNEILPHAAKGALIIDCSTID-VESAVQAHALAAKHD--------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  +DAPVSGGT  A   TLT + GG+  + AA  P+L  MG+  VH G  GAGQ  K
Sbjct: 111 --IASVDAPVSGGTGGAKGATLTFMAGGSEAAFAAAKPVLEQMGKKIVHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVSEAFTLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[165][TOP]
>UniRef100_A9M5X6 3-hydroxyisobutyrate dehydrogenase n=3 Tax=Brucella
           RepID=A9M5X6_BRUC2
          Length = 296

 Score =  108 bits (271), Expect = 2e-22
 Identities = 69/170 (40%), Positives = 93/170 (54%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V +    +AP+A   ++ +D STI   +S   A  +AA  G        
Sbjct: 60  AVITMLPAGKHVISVYEDIAPKARKDSLFVDCSTID-VDSARKAHELAATHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[166][TOP]
>UniRef100_A9F2T6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Phaeobacter
           gallaeciensis 2.10 RepID=A9F2T6_9RHOB
          Length = 291

 Score =  108 bits (271), Expect = 2e-22
 Identities = 67/168 (39%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + A    + P    GA L+D ST+    +RA+A           D  GS 
Sbjct: 55  VITMLPNGQILRAVADDVIPAMAEGATLVDCSTVDVDSARAVA-----------DQAGSA 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             + V DAPVSGG   A+ GTLT + GG++ + AA  PL  IMG + VH G  GAGQ  K
Sbjct: 104 NLMFV-DAPVSGGIGGASGGTLTFMAGGSAAAFAAAEPLFDIMGQKAVHCGDAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M    EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGITMIGTCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[167][TOP]
>UniRef100_UPI0000F2E77E PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase,
           mitochondrial precursor (HIBADH) n=1 Tax=Monodelphis
           domestica RepID=UPI0000F2E77E
          Length = 341

 Score =  108 bits (270), Expect = 2e-22
 Identities = 70/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA---AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++     V    + +  +   G++LID STI P+ S+ LA  V   MG      
Sbjct: 104 IITMLPTSLNAIEVYTGPNGILRKVKKGSLLIDSSTIDPSVSKELAKEVEK-MGA----- 157

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA AG LT +VGG     AA   LL  MG   V+ GA G G+
Sbjct: 158 ------LFMDAPVSGGVGAARAGNLTFMVGGPEQEFAAAKELLGCMGSNVVYCGAVGTGE 211

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++LG SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 212 AAKICNNMLLGISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 263

[168][TOP]
>UniRef100_Q5BKJ0 MGC108315 protein n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=Q5BKJ0_XENTR
          Length = 328

 Score =  108 bits (270), Expect = 2e-22
 Identities = 70/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA---AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+A    V    + +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 92  IITMLPSSANAIEVYTGSNGILKKVKKGSLLIDSSTIDPAVSKELAKAVEKM-------- 143

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG      A   LLS MG   V+ GA G GQ
Sbjct: 144 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEQEFDAAKELLSCMGANVVYCGAVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   +E   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAISMIGTSETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 251

[169][TOP]
>UniRef100_Q28R38 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28R38_JANSC
          Length = 290

 Score =  108 bits (270), Expect = 2e-22
 Identities = 68/168 (40%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + A    + P     AV +D ST+    +R +A + A        D G G
Sbjct: 55  VITMLPNGAILRAVAAEIIPAMAPDAVFVDCSTVEVDAAREVAEQAA--------DAGLG 106

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                LDAPVSGG   AA GTLT +VGG+ D+ A V PL  IMG + V  G  G GQ  K
Sbjct: 107 W----LDAPVSGGVGGAAGGTLTFMVGGSEDAFARVQPLFDIMGQKAVLCGPAGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA A+A   G+   +   V++TSSG  W  + Y
Sbjct: 163 ICNNMILGVTMIATCEAFAMADKLGLARQSMFDVVSTSSGYSWTMNAY 210

[170][TOP]
>UniRef100_C6B6Q4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhizobium leguminosarum
           bv. trifolii WSM1325 RepID=C6B6Q4_RHILS
          Length = 293

 Score =  108 bits (270), Expect = 2e-22
 Identities = 68/170 (40%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDGG 198
           +ITMLP    V      +   A  G ++ID STI    SR     A+ A+ +        
Sbjct: 61  IITMLPQGKHVLTAWTDILQSAAQGMLVIDCSTIDVDSSRKAHEMAKAASCLS------- 113

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
                  LDAPVSGGT  A AGTLT + GG  D+ A   P+L  MG+  VH G  GAGQ 
Sbjct: 114 -------LDAPVSGGTGGATAGTLTFMAGGTEDAFARAKPILEAMGKKIVHCGEAGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+ + Y
Sbjct: 167 AKICNNMILGISMVGVCEAFVLAEKLGLSHQALFDVASTSSGQCWSINTY 216

[171][TOP]
>UniRef100_A9CG44 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Agrobacterium
           tumefaciens str. C58 RepID=A9CG44_AGRT5
          Length = 294

 Score =  108 bits (270), Expect = 2e-22
 Identities = 69/168 (41%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP    V +    L  +   G +LID ST+   ES   A  +AA  G         
Sbjct: 61  VITMLPKGEHVVSVYGDLVRKVSAGTLLIDCSTVD-MESALKAHELAASAGCPS------ 113

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                +DAPVSGGT+ AAAGTLT + GG  D+ +A  P+L  MG+  VH G  G GQ  K
Sbjct: 114 -----VDAPVSGGTSGAAAGTLTFMCGGEPDAFSAARPVLEAMGKKIVHCGKGGNGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM AV+EA  L    G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIAVSEAFVLGEKLGLSHQALFDVASTSSGQCWSLTTY 216

[172][TOP]
>UniRef100_B9QV22 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Labrenzia alexandrii
           DFL-11 RepID=B9QV22_9RHOB
          Length = 296

 Score =  108 bits (270), Expect = 2e-22
 Identities = 66/171 (38%), Positives = 90/171 (52%), Gaps = 4/171 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +++MLP+   V         +   A  G +LID STI    +RA++A  A          
Sbjct: 62  IVSMLPAGKHVRQVYMGEGGILDNAKAGTLLIDSSTIDVDSARAVSAAAA---------- 111

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
             G  + ++DAPVSGG A AAAGTLT +VGG   +  A  P L IMG+  VH G  G GQ
Sbjct: 112 --GKSMPIVDAPVSGGVAGAAAGTLTFMVGGEDSAFEAAKPYLDIMGKTIVHAGGAGTGQ 169

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             K  NN++LG SM  V+EA  LA   G+       + +T+SG+CW+   Y
Sbjct: 170 AAKICNNMILGISMIGVSEAFVLAERLGLDAQKLFDISSTASGQCWSLTSY 220

[173][TOP]
>UniRef100_Q2HJD7 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Bos
           taurus RepID=3HIDH_BOVIN
          Length = 336

 Score =  108 bits (270), Expect = 2e-22
 Identities = 72/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI P  S+ LA  V  +        
Sbjct: 99  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPMVSKELAKEVEKM-------- 150

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG  +  AA   LL  MG   V+ GA G GQ
Sbjct: 151 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEEEFAAAQELLGCMGSNVVYCGAVGTGQ 206

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NNL+L  SM   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 207 AAKICNNLLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 258

[174][TOP]
>UniRef100_UPI000155C6B7 PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase,
           mitochondrial precursor (HIBADH) n=1 Tax=Ornithorhynchus
           anatinus RepID=UPI000155C6B7
          Length = 337

 Score =  108 bits (269), Expect = 3e-22
 Identities = 73/172 (42%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLH--ALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  A+ A      +  +   G++LID STI PA S+ LA + A  MG      
Sbjct: 100 IITMLPSSLNAIEAYTGPTGILKKVKKGSLLIDSSTIDPAVSKELA-KEAEKMGAV---- 154

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA AG LT +VGGA    AA   LL  MG   V  GA G GQ
Sbjct: 155 -------FMDAPVSGGVGAARAGNLTFMVGGAEQEFAAAKELLGCMGSNVVFCGAVGTGQ 207

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L   M   AEA  L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 208 AAKICNNMLLAIGMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 259

[175][TOP]
>UniRef100_Q6NRB2 MGC84587 protein n=1 Tax=Xenopus laevis RepID=Q6NRB2_XENLA
          Length = 328

 Score =  108 bits (269), Expect = 3e-22
 Identities = 70/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA---AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+A    V    + +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 92  IITMLPSSANATEVYTGSNGILKKVKKGSLLIDSSTIDPAVSKELAKGVEKM-------- 143

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG      A   LLS MG   V+ GA G GQ
Sbjct: 144 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEQEFDAAKELLSCMGANVVYCGAVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   +E   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAISMIGTSETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 251

[176][TOP]
>UniRef100_Q164T3 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseobacter
           denitrificans OCh 114 RepID=Q164T3_ROSDO
          Length = 641

 Score =  108 bits (269), Expect = 3e-22
 Identities = 64/168 (38%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +++MLP+ A +      + P    GA+ +D ST+    +RA+A                 
Sbjct: 405 VLSMLPNGAILRDVASTVLPVMKPGALFLDCSTVDVDSARAVA------------QAARD 452

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             V  +DAPVSGG   AAAGTLT + GG++++     PL  IMG + VH GA GAGQ  K
Sbjct: 453 ASVQFVDAPVSGGVGGAAAGTLTFMAGGSAEAFETARPLFDIMGQKAVHCGAPGAGQAAK 512

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 513 ICNNMILGATMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 560

[177][TOP]
>UniRef100_B1M7T1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Methylobacterium
           radiotolerans JCM 2831 RepID=B1M7T1_METRJ
          Length = 290

 Score =  108 bits (269), Expect = 3e-22
 Identities = 71/163 (43%), Positives = 86/163 (52%), Gaps = 3/163 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL--HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           LITMLP++A V A L     A   P GA +IDMS+  P  SRAL   +A           
Sbjct: 62  LITMLPNSAIVEAVLLDDGWADALPAGATVIDMSSSEPVRSRALGETLA----------- 110

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQV 375
            G  +  LDAPVSGG   A  GTL I+VGGA+D +A   P+L  MG  V H+G  G+G  
Sbjct: 111 -GKGLGYLDAPVSGGVKRAVNGTLAILVGGAADLLARWRPVLEAMGTSVLHIGPAGSGHA 169

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGR 504
            KA NN V  A + A  EA  +A   G+ P     VL  SSGR
Sbjct: 170 AKALNNFVSAAGLLATVEALHVAQRFGIAPEAMTDVLNASSGR 212

[178][TOP]
>UniRef100_B9SB22 3-hydroxyisobutyrate dehydrogenase, putative n=1 Tax=Ricinus
           communis RepID=B9SB22_RICCO
          Length = 388

 Score =  108 bits (269), Expect = 3e-22
 Identities = 69/174 (39%), Positives = 94/174 (54%), Gaps = 6/174 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVL-----IDMSTIPPAESRALAARVAAVMGGGDD 189
           +ITMLPST+ V    +        G  L     I+ STI P  SR L+A V+  +    +
Sbjct: 138 VITMLPSTSHVLDVYNGPNGLLQGGTFLRPQLFINSSTIDPETSRKLSAAVSNFVV--KE 195

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGA 366
             G+  +  +LDAPVSGG  AA AGTLT +VGG+ D+  A  PL   MG+  ++ G  G 
Sbjct: 196 KTGNWEKPLMLDAPVSGGVLAAEAGTLTFMVGGSKDAYLAAKPLFLSMGKSTIYCGGAGT 255

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G   K  NNL +  SM  V+EA AL  + G+   T   V  +SS RCW++D Y+
Sbjct: 256 GSAAKICNNLAMAVSMLGVSEALALGQSLGIDADTLTKVFNSSSARCWSSDSYN 309

[179][TOP]
>UniRef100_UPI0001B487F1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Brucella sp. 83/13
           RepID=UPI0001B487F1
          Length = 296

 Score =  107 bits (268), Expect = 4e-22
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+IT+LP+   V +    +AP+A   ++ ID STI   +S   A  +AA  G        
Sbjct: 60  AVITILPAGKHVISVYEDIAPKARKDSLFIDCSTID-VDSAHKAHELAAAHG-------- 110

Query: 202 GGRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQV 375
               H+ +DAPVSGGT  AAAGTLT + GG+ ++     P+L  M G+ VH G  GAGQ 
Sbjct: 111 ----HLSIDAPVSGGTGGAAAGTLTFMAGGSEEAFKRGEPILQPMAGKIVHCGGDGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 167 AKICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[180][TOP]
>UniRef100_UPI000155E196 PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase,
           mitochondrial precursor (HIBADH) n=1 Tax=Equus caballus
           RepID=UPI000155E196
          Length = 336

 Score =  107 bits (268), Expect = 4e-22
 Identities = 72/172 (41%), Positives = 93/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTA-AVAATLHA--LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP++  A+ A   A  +  +   G++LID STI PA S+ LA + A  MG      
Sbjct: 99  IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAISKELA-KEAEKMGAV---- 153

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA +G LT +VGG  D  AA   LL  MG   V+ GA G GQ
Sbjct: 154 -------FMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQ 206

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   AE   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 207 AAKICNNMLLAISMIGTAETMNLGIRLGLDPKLLAKILNMSSGRCWSSDSYN 258

[181][TOP]
>UniRef100_Q92TQ7 Putative 3-hydroxyisobutyrate dehydrogenase protein n=1
           Tax=Sinorhizobium meliloti RepID=Q92TQ7_RHIME
          Length = 298

 Score =  107 bits (268), Expect = 4e-22
 Identities = 72/168 (42%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP++A V      L      G +LID STI    +R        V G  +  G   
Sbjct: 61  VITMLPASAHVLYVWDELLGFVDPGTLLIDSSTIDVESARK-------VHGFAEKAGCPS 113

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                LDAPVSGGTA AAA TLT +VGG+  + +    LL  MG+  VH G  GAGQ  K
Sbjct: 114 -----LDAPVSGGTAGAAAATLTFMVGGSEGAFSRGKHLLEAMGKKIVHCGDAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SMAAV EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGVSMAAVCEAFVLAERLGLSHQALFDVASTSSGQCWSLTTY 216

[182][TOP]
>UniRef100_Q89N85 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Bradyrhizobium japonicum
           RepID=Q89N85_BRAJA
          Length = 295

 Score =  107 bits (268), Expect = 4e-22
 Identities = 69/168 (41%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V    + + P    GA++ID STI   ES   A  +AA  G         
Sbjct: 61  VVTMLPAGKHVLGVWNEVVPVMTKGALIIDSSTID-VESARQAHALAAKNG--------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             V  +DAPVSGGT  A   TLT + GG   + AA  P+L  MG+  VH G  GAGQ  K
Sbjct: 111 --VLSVDAPVSGGTGGAKGATLTFMCGGEDKAFAAAKPVLENMGKKIVHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM AV+EA AL    G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIAVSEAFALGEKLGLSHQALFDVASTSSGQCWSLTTY 216

[183][TOP]
>UniRef100_Q3KIG6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas fluorescens
           Pf0-1 RepID=Q3KIG6_PSEPF
          Length = 295

 Score =  107 bits (268), Expect = 4e-22
 Identities = 68/172 (39%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V +       +      G   +D STI P  +R +AA  AA  G      
Sbjct: 60  VITMLPAAVHVRSVWLGEDGVLAGIGKGVPAVDCSTIDPQTARDVAA-AAAKQG------ 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                V + DAPVSGGT  A AGTLT +VG   +  A + P+L+ MGR  VH G  G GQ
Sbjct: 113 -----VAMADAPVSGGTGGATAGTLTFMVGTTPELFATLQPVLAQMGRNIVHCGEVGTGQ 167

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           + K  NNL+L  SM  V+EA AL  A G+     A ++ +S+GRCW++++Y+
Sbjct: 168 IAKICNNLLLAISMVGVSEAMALGDALGIDTTVLAGIINSSTGRCWSSEMYN 219

[184][TOP]
>UniRef100_Q11IS1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Chelativorans sp. BNC1
           RepID=Q11IS1_MESSB
          Length = 294

 Score =  107 bits (268), Expect = 4e-22
 Identities = 70/169 (41%), Positives = 91/169 (53%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP+   V      +  +A  G + ID STI  A     +ARVA +M         
Sbjct: 60  AIITMLPAGKHVLTVYEDILAKAAAGTLFIDSSTIDVA-----SARVAHLMAR------K 108

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVV 378
            G + V DAPVSGG   A AG+LT + GG++++ A   P+L  M GR VH G  GAGQ  
Sbjct: 109 HGHLSV-DAPVSGGVVGAEAGSLTFMAGGSAEAFAKAEPILKPMAGRIVHCGDGGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  VAEA  LA   G+       V + SSG+CW+   Y
Sbjct: 168 KICNNMILGISMIGVAEAFVLAEKLGLSHQALFEVASASSGQCWSLTTY 216

[185][TOP]
>UniRef100_Q0SGI4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodococcus jostii RHA1
           RepID=Q0SGI4_RHOSR
          Length = 299

 Score =  107 bits (268), Expect = 4e-22
 Identities = 67/164 (40%), Positives = 85/164 (51%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLPS   V      + P A  G + ID STI  A++RA             D+    
Sbjct: 62  VITMLPSGKHVLGLYAEILPAAKPGTLFIDSSTIDVADARA-----------AHDEAVEA 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
           G   V DAPVSGG   A AGTL  +VGG +D   +  PLL +MG+ V H G  G GQ  K
Sbjct: 111 GHRSV-DAPVSGGVVGATAGTLAFMVGGTADDFESAKPLLDVMGKKVVHCGDPGNGQAAK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM AV+EA  L    G+       V + +SG+CWA
Sbjct: 170 ICNNMILGVSMIAVSEAFVLGEKLGLSNQALFDVASNASGQCWA 213

[186][TOP]
>UniRef100_A5WC61 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Psychrobacter sp. PRwf-1
           RepID=A5WC61_PSYWF
          Length = 309

 Score =  107 bits (268), Expect = 4e-22
 Identities = 69/180 (38%), Positives = 94/180 (52%), Gaps = 12/180 (6%)
 Frame = +1

Query: 25  LITMLPSTA-----------AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAV 171
           +ITMLP++            A   T   L    P G ++ID STI  A +R +A R+A  
Sbjct: 65  VITMLPASKHVNTVYLGDAEATQLTADGLLSELPSGTLVIDSSTIDAAAARNVA-RIATT 123

Query: 172 MGGGDDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-H 348
            G           + ++DAPVSGGTA A AGTLT IVGG   +     P+L  MG+ + H
Sbjct: 124 KG-----------IDMVDAPVSGGTAGAEAGTLTFIVGGEDSAFNRAEPILKAMGKNIFH 172

Query: 349 VGACGAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
            G+ GAGQV K  NN++LG  M+  AEA  L    G+     + ++  SSGR W  +VY+
Sbjct: 173 AGSNGAGQVAKICNNMLLGILMSGTAEALNLGVKNGLDAKVLSDIMLQSSGRNWTLEVYN 232

[187][TOP]
>UniRef100_A0KK12 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Aeromonas hydrophila
           subsp. hydrophila ATCC 7966 RepID=A0KK12_AERHH
          Length = 306

 Score =  107 bits (268), Expect = 4e-22
 Identities = 62/147 (42%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
 Frame = +1

Query: 91  PVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSGGRVHVLDAPVSGGTAAAAAGTL 270
           P+GA++ID STI  A +R + A   A              +  LDAPVSGG A AAAGTL
Sbjct: 93  PLGALVIDCSTIDVASARQVGAAAQA------------RGIRFLDAPVSGGVAGAAAGTL 140

Query: 271 TIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVKAANNLVLGASMAAVAEATALAA 447
           T IVGG      A  P+L+ MG+ + H GA GAGQ+ K  NN++L   MA  AEA AL  
Sbjct: 141 TFIVGGEQADFEAAKPVLACMGQNLFHAGALGAGQIAKMCNNMLLAIHMAGTAEALALGV 200

Query: 448 AAGVPPVTTAVVLATSSGRCWAADVYH 528
             G+ P   + ++  SSG  W+ + Y+
Sbjct: 201 KEGLDPGVLSTIMGKSSGNNWSLERYN 227

[188][TOP]
>UniRef100_C9D450 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Silicibacter sp.
           TrichCH4B RepID=C9D450_9RHOB
          Length = 290

 Score =  107 bits (268), Expect = 4e-22
 Identities = 64/168 (38%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   +      + P    GA  +D ST+    +RA+A + AA            
Sbjct: 55  VITMLPNGDILRHVASEIIPAMGAGAAFVDCSTVDVDSARAVADQAAAA----------- 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AA GTLT + GG++++ A   PL  IMG + VH G  GAGQ  K
Sbjct: 104 -GLLAVDAPVSGGIGGAAGGTLTFMAGGSAEAFAKAAPLFDIMGQKAVHCGDAGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 210

[189][TOP]
>UniRef100_B9NSD9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacteraceae
           bacterium KLH11 RepID=B9NSD9_9RHOB
          Length = 276

 Score =  107 bits (268), Expect = 4e-22
 Identities = 69/169 (40%), Positives = 90/169 (53%), Gaps = 1/169 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A++TMLP+   + A    + P     AVLID ST+    +RA+A + A      D D  S
Sbjct: 40  AVVTMLPNGQILRAVADEVIPAMQEEAVLIDCSTVDVDSARAVAQQAA------DADLLS 93

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVV 378
                 +DAPVSGG   AAAGTLT + GG   + A   PL  IMG + VH G  G+GQ  
Sbjct: 94  ------VDAPVSGGIGGAAAGTLTFMAGGTDAAFAKAAPLFDIMGQKAVHCGEAGSGQAA 147

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG +M A  EA ALA   G+       V++TSSG  W  + Y
Sbjct: 148 KICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWTMNAY 196

[190][TOP]
>UniRef100_B4JA17 GH19800 n=1 Tax=Drosophila grimshawi RepID=B4JA17_DROGR
          Length = 322

 Score =  107 bits (268), Expect = 4e-22
 Identities = 67/170 (39%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHAL-APRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           +ITMLP+   V A+   + A       + ID STI P   ++L  R++A           
Sbjct: 88  VITMLPNNDIVDASYEEMTANGVNKNTIFIDSSTIDPVLVKSLQKRISA----------K 137

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVV 378
           G R   +DAPVSGG   A   TLT +VGG +D   AV  +L  MG+ + H G  G GQ  
Sbjct: 138 GARF--IDAPVSGGVPGAEQATLTFMVGGTTDEYNAVKAVLECMGKRITHCGDYGMGQAA 195

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           K ANN++L  SM  V+EA  LA   G+ P T A ++ +S+GRCWA+++Y+
Sbjct: 196 KLANNMMLAISMIGVSEAMNLAIRLGLNPKTFAEIINSSTGRCWASELYN 245

[191][TOP]
>UniRef100_Q54CX6 Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1
           Tax=Dictyostelium discoideum RepID=3HIDH_DICDI
          Length = 321

 Score =  107 bits (268), Expect = 4e-22
 Identities = 67/172 (38%), Positives = 89/172 (51%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP++A V       + +      G +L+D STI PA +R +A+             
Sbjct: 82  IVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQST----- 136

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQ 372
                  +LD PVSGGT  A AGTLT +VGG+          L  MG+  VH G  G GQ
Sbjct: 137 -------MLDCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQ 189

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NNLVLG SM AV+EA  L    G+ P   A +  TSS RCW +++Y+
Sbjct: 190 VAKVCNNLVLGISMIAVSEAMNLGVKQGMDPKKLAGIFNTSSARCWTSELYN 241

[192][TOP]
>UniRef100_Q5XGV0 LOC495134 protein n=1 Tax=Xenopus laevis RepID=Q5XGV0_XENLA
          Length = 328

 Score =  107 bits (267), Expect = 5e-22
 Identities = 69/172 (40%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+A         + +  +   G++LID STI PA S+ LA  V  +        
Sbjct: 92  IITMLPSSANAVEAYSGSNGILKKVKKGSLLIDSSTIDPAVSKDLAKAVEKM-------- 143

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
              G V  +DAPVSGG  AA +G LT +VGG      A   LLS MG  V + GA G GQ
Sbjct: 144 ---GAVF-MDAPVSGGVGAARSGNLTFMVGGVEQEFDAAKELLSCMGANVIYCGAVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L  SM   +E   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAISMIGTSETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 251

[193][TOP]
>UniRef100_A8DSV9 Hibadhb n=1 Tax=Haplochromis burtoni RepID=A8DSV9_HAPBU
          Length = 329

 Score =  107 bits (267), Expect = 5e-22
 Identities = 68/172 (39%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  V       + +  +   G++LID STI PA S+ +AA           D 
Sbjct: 92  IITMLPSSPNVIDVYTGPNGILKKVKKGSLLIDSSTIDPAVSKEMAA-----------DA 140

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
              G V  +DAPVSGG  AA++G LT +VGGA +   A   LLS MG  V + G  G GQ
Sbjct: 141 EKMGAVF-MDAPVSGGVGAASSGKLTFMVGGAEEEFTAAKELLSCMGANVIYCGQVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L   M   +E   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAIGMIGTSETMNLGIRLGLDPKLLAQILNMSSGRCWSSDTYN 251

[194][TOP]
>UniRef100_Q6N493 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodopseudomonas
           palustris RepID=Q6N493_RHOPA
          Length = 295

 Score =  107 bits (267), Expect = 5e-22
 Identities = 67/168 (39%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V A  + + P A  GA++ID STI   ES   A  +A             
Sbjct: 61  IVTMLPAGKHVLAVWNEILPHAAKGALIIDCSTID-VESAVQAHALATKHD--------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  +DAPVSGGT  A   TLT + GG+  + AA  P+L  MG+  VH G  GAGQ  K
Sbjct: 111 --IASVDAPVSGGTGGAKGATLTFMAGGSEAAFAAAKPVLEQMGKKIVHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVSEAFTLAEKLGLSHQALFDVASTSSGQCWSLTSY 216

[195][TOP]
>UniRef100_A6X032 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ochrobactrum anthropi
           ATCC 49188 RepID=A6X032_OCHA4
          Length = 296

 Score =  107 bits (267), Expect = 5e-22
 Identities = 69/169 (40%), Positives = 92/169 (54%), Gaps = 2/169 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V +    +AP A   ++ ID STI   +S   A  +AA  G         
Sbjct: 61  VITMLPAGKHVLSVYEDIAPNARKDSLFIDCSTID-VDSARKAHELAASHG--------- 110

Query: 205 GRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVV 378
              H+ +DAPVSGGT  A+AGTLT + GG+ D+     P+L  M G+ VH G  GAGQ  
Sbjct: 111 ---HLSIDAPVSGGTGGASAGTLTFMAGGSDDAFTRGEPILQPMAGKIVHCGGDGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[196][TOP]
>UniRef100_Q0QLF5 2-hydroxymethyl glutarate dehydrogenase n=1 Tax=Eubacterium barkeri
           RepID=Q0QLF5_EUBBA
          Length = 301

 Score =  107 bits (267), Expect = 5e-22
 Identities = 63/169 (37%), Positives = 95/169 (56%), Gaps = 4/169 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           + T LP+   V   ++    +      G V++DMS++ P+ +  +A +VAA  G      
Sbjct: 64  IFTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMA-KVAAEKG------ 116

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +  +DAPVSGGT  A AGTLTI+VG +      + P+LS++G+ + HVG  GAG 
Sbjct: 117 -----IDYVDAPVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGD 171

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAAD 519
            VK  NNL+LG +MA++AEA  L    G+ P T   ++  SSGR +A +
Sbjct: 172 AVKIVNNLLLGCNMASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAME 220

[197][TOP]
>UniRef100_C8PZQ2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Enhydrobacter aerosaccus
           SK60 RepID=C8PZQ2_9GAMM
          Length = 308

 Score =  107 bits (267), Expect = 5e-22
 Identities = 69/173 (39%), Positives = 92/173 (53%), Gaps = 7/173 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +ITMLP+   V            L        +L+D STI  +++R +A   A       
Sbjct: 69  VITMLPAGQHVKEVYLGKDGNQGLLDVVGKNTLLVDSSTIAASDAREVAEAAA------- 121

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
           D G     +  +DAPVSGGTA AAAGTL+ IVGG ++    V P+L  MG+ + H G  G
Sbjct: 122 DKG-----IQFMDAPVSGGTAGAAAGTLSFIVGGQAEQFEQVKPVLEAMGKNIFHAGEVG 176

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           AGQV K  NN++LG  M   AEA  L A  G+ P   A +L+ S+GR WA +V
Sbjct: 177 AGQVAKICNNMLLGVIMTGTAEAMNLGAKNGLDPKVLASILSASTGRNWALEV 229

[198][TOP]
>UniRef100_C1A225 3-hydroxyisobutyrate dehydrogenase n=2 Tax=Rhodococcus erythropolis
           RepID=C1A225_RHOE4
          Length = 297

 Score =  107 bits (267), Expect = 5e-22
 Identities = 67/164 (40%), Positives = 86/164 (52%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLPS   V      L P A  G + ID STI  A++R    +  A          +G
Sbjct: 61  VITMLPSGKHVLGLYEELLPVATPGTLFIDCSTIDVADAREAHDKAEA----------AG 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
            R   +DAPVSGG   A AGTL  +VGG+     A +PLL +MGR V H G  G GQ  K
Sbjct: 111 HRS--VDAPVSGGVVGATAGTLAFMVGGSEADFQAASPLLDVMGRKVVHCGDAGVGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM A++EA  L    G+       V + +SG+CWA
Sbjct: 169 ICNNMILGISMIAISEAFVLGEKLGLSNQALFDVASNASGQCWA 212

[199][TOP]
>UniRef100_B6AV67 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacterales
           bacterium HTCC2083 RepID=B6AV67_9RHOB
          Length = 638

 Score =  107 bits (267), Expect = 5e-22
 Identities = 66/168 (39%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A + +    + P    GAV++D ST+    +R +AA   A            
Sbjct: 403 VITMLPNGAILRSVAEEVIPAMGAGAVMLDCSTVDVESARDVAALCDAA----------- 451

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             V  LDAPVSGG   A+ GTLT +VGG  +      PL  IMG + VH GA G GQ  K
Sbjct: 452 -GVLPLDAPVSGGVGGASGGTLTFMVGGNENGFQKALPLFEIMGQKSVHCGASGNGQAAK 510

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M A  E+ ALA   G+       V++TSSG  W+ + Y
Sbjct: 511 ICNNMILGATMIATCESFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 558

[200][TOP]
>UniRef100_Q5RF30 Putative uncharacterized protein DKFZp469F1932 n=1 Tax=Pongo abelii
           RepID=Q5RF30_PONAB
          Length = 235

 Score =  107 bits (267), Expect = 5e-22
 Identities = 65/145 (44%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
 Frame = +1

Query: 97  GAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSGGRVHVLDAPVSGGTAAAAAGTLTI 276
           G++LID STI PA S+ LA  V  +           G V  +DAPVSGG  AA +G LT 
Sbjct: 25  GSLLIDSSTIDPAVSKELAKEVEKM-----------GAVF-MDAPVSGGVGAARSGNLTF 72

Query: 277 IVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVKAANNLVLGASMAAVAEATALAAAA 453
           +VGG  D  AA   LL  MG   V+ GA G GQ  K  NN++L  SM   AEA  L    
Sbjct: 73  MVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRL 132

Query: 454 GVPPVTTAVVLATSSGRCWAADVYH 528
           G+ P   A +L  SSGRCW++D Y+
Sbjct: 133 GLDPKLLAKILNMSSGRCWSSDTYN 157

[201][TOP]
>UniRef100_Q9SUC0 Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=2
           Tax=Arabidopsis thaliana RepID=3HIDH_ARATH
          Length = 347

 Score =  107 bits (267), Expect = 5e-22
 Identities = 69/174 (39%), Positives = 91/174 (52%), Gaps = 6/174 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA-----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDD 189
           +ITMLPS++ V           L       A+ ID STI P  +R ++  V+        
Sbjct: 97  VITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKISLAVSNCNLKEKR 156

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGA 366
           D     +  +LDAPVSGG  AA AGTLT +VGG  D+  A  P+L  MGR  ++ G  G 
Sbjct: 157 DNWE--KPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMGRTSIYCGGSGN 214

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G   K  NNL +  SM   +EA AL  + G+   T   VL TSSGRCW++D Y+
Sbjct: 215 GSAAKICNNLAMAVSMLGTSEALALGQSLGISASTLTEVLNTSSGRCWSSDAYN 268

[202][TOP]
>UniRef100_C3KM95 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhizobium sp. NGR234
           RepID=C3KM95_RHISN
          Length = 298

 Score =  107 bits (266), Expect = 7e-22
 Identities = 71/168 (42%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ + V      L      G ++ID STI    +R + A          D  G  
Sbjct: 61  VITMLPAGSHVIYVWDELLGFVDPGTLIIDSSTIDVESARKVHAFA--------DKAGCP 112

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                LDAPVSGGTA AAAGTLT +VGG+  + +    LL  MG+  VH G  GAGQ  K
Sbjct: 113 S----LDAPVSGGTAGAAAGTLTFMVGGSDGAFSRGKHLLEAMGKKIVHCGDAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SMAAV EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGVSMAAVCEAFVLAERLGLSHQALFDVASTSSGQCWSLTSY 216

[203][TOP]
>UniRef100_A4TEE1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Mycobacterium gilvum
           PYR-GCK RepID=A4TEE1_MYCGI
          Length = 290

 Score =  107 bits (266), Expect = 7e-22
 Identities = 62/164 (37%), Positives = 87/164 (53%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++T LP+ A V A    + P A  GA+LID STI   ++RA+  +  A            
Sbjct: 61  VVTSLPNGAVVKAVYDEVVPAAKAGALLIDTSTISVDDARAIHEQATA------------ 108

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVVK 381
           G +  +DAPVSGG   A AGTL  +VGG  ++     P+L  M G+ +H GA GAGQ  K
Sbjct: 109 GGLAQIDAPVSGGIKGATAGTLAFMVGGDDEAFERAKPVLEPMAGKIIHCGASGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN+VL     A+ EA  LA   G+P  +   V+  ++G CW+
Sbjct: 169 LCNNMVLAVQQIAIGEAFVLAEKLGLPAQSLFDVITGATGNCWS 212

[204][TOP]
>UniRef100_A1TQD4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acidovorax citrulli
           AAC00-1 RepID=A1TQD4_ACIAC
          Length = 299

 Score =  107 bits (266), Expect = 7e-22
 Identities = 67/175 (38%), Positives = 91/175 (52%), Gaps = 7/175 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL------HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +I+MLP++  V A          L P+   G ++ID STI  A SR +A           
Sbjct: 60  VISMLPASPHVEALFLGGGQQPGLLPQLAAGTLVIDCSTIAAATSRKVA----------- 108

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
            D      +  +DAPVSGGT  A AGTLT +VGG +  +    P+L  MG  + H G  G
Sbjct: 109 -DAARERGIAFIDAPVSGGTGGAVAGTLTFMVGGDAADLERARPVLEKMGANIFHAGGVG 167

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           AGQ  K  NN++LG  MA  +EA AL AA G+ P   + ++  SSG  WA + Y+
Sbjct: 168 AGQTAKICNNMLLGILMAGTSEALALGAANGLDPAVLSEIMRRSSGGNWALEKYN 222

[205][TOP]
>UniRef100_UPI00017C2AB4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Acyrthosiphon pisum
           RepID=UPI00017C2AB4
          Length = 328

 Score =  106 bits (265), Expect = 9e-22
 Identities = 66/168 (39%), Positives = 89/168 (52%), Gaps = 1/168 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP +  V +   AL   +    + +D STI P  S+ ++            D   
Sbjct: 93  AVITMLPESQHVLSAYSALLESSKPEQLFVDCSTISPESSKKVS------------DMAE 140

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVV 378
                 L APVSGG   A  GTLT +VGG   ++ A   LL  MG R V+ G  G+G V 
Sbjct: 141 KKGCKFLGAPVSGGVVGAENGTLTFMVGGDESTLTAAEHLLGSMGSRWVYCGPAGSGLVA 200

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
           K  NN++LG +MAAVAEA  L    G+ P   A V+ TS+GRCWA+++
Sbjct: 201 KICNNMILGMTMAAVAEAMNLGIKLGMEPKVLASVINTSTGRCWASEI 248

[206][TOP]
>UniRef100_Q87H47 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Vibrio parahaemolyticus
           RepID=Q87H47_VIBPA
          Length = 298

 Score =  106 bits (265), Expect = 9e-22
 Identities = 64/172 (37%), Positives = 96/172 (55%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP++  V +     + +      G +LID STI PA +R++  + A + G      
Sbjct: 61  VVTMLPASQHVQSVYLGQYGILDSVDAGTLLIDSSTIDPATARSVGEQ-AELRG------ 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +  +DAPVSGG A AAAGTLT IVGG+ ++      +L+ MG+ + H G  GAGQ
Sbjct: 114 -----ISFVDAPVSGGVAGAAAGTLTFIVGGSQENFVQAKAVLNHMGKNIFHAGDAGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  M+   EA  L    G+ P   + ++  SSGR WA ++Y+
Sbjct: 169 VAKICNNMMLGILMSGTCEALNLGMENGLDPKVLSDIMLQSSGRNWALELYN 220

[207][TOP]
>UniRef100_Q2SP85 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Hahella chejuensis KCTC
           2396 RepID=Q2SP85_HAHCH
          Length = 296

 Score =  106 bits (265), Expect = 9e-22
 Identities = 68/173 (39%), Positives = 92/173 (53%), Gaps = 4/173 (2%)
 Frame = +1

Query: 22  ALITMLPSTA---AVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           A++TMLP++    AV    + L  +     +LID STI P  SR +AA            
Sbjct: 60  AVVTMLPASEHSEAVYLGENGLLNQLSERPLLIDCSTIAPETSRRIAAEA---------- 109

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAG 369
             S     +LDAPVSGGTA A AGTLT I+GGA   +    P+LS MG+ + H G  GAG
Sbjct: 110 --SKKGFAMLDAPVSGGTAGATAGTLTFIIGGAPQDLEKAQPILSAMGKNLFHAGDHGAG 167

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           Q  K  NN++L   M   AEA  L    G+ P   + ++  SSGR W+ ++Y+
Sbjct: 168 QAAKICNNMLLAVHMIGTAEALQLGVNLGLDPKVLSDIMLKSSGRNWSLELYN 220

[208][TOP]
>UniRef100_B6A4Z0 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhizobium leguminosarum
           bv. trifolii WSM2304 RepID=B6A4Z0_RHILW
          Length = 281

 Score =  106 bits (265), Expect = 9e-22
 Identities = 65/168 (38%), Positives = 84/168 (50%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   +      L      G+V  D STI    +RA+A   A             
Sbjct: 45  VITMLPNGTVLREVAEQLIGALVPGSVFCDCSTIDVESARAVAVMAARA----------- 93

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  LDAPVSGG   A AGTLT +VGG   +   + PLL +MG + VH G  GAGQ  K
Sbjct: 94  -NIDALDAPVSGGVGGAVAGTLTFMVGGTEAAYGKIKPLLDVMGSKAVHCGPSGAGQSAK 152

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W  + Y
Sbjct: 153 ICNNMILGVTMVATCEAFALADKLGLERQKMFEVVSTSSGSSWTMNSY 200

[209][TOP]
>UniRef100_B1LTH4 2-hydroxy-3-oxopropionate reductase n=1 Tax=Methylobacterium
           radiotolerans JCM 2831 RepID=B1LTH4_METRJ
          Length = 301

 Score =  106 bits (265), Expect = 9e-22
 Identities = 70/171 (40%), Positives = 97/171 (56%), Gaps = 4/171 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           L   LP+  AV A L    ALA R   GAV++D+ST+   ++ A+   VAA         
Sbjct: 65  LFLCLPNGDAVEAALLGTGALAERLAPGAVVVDLSTVAHDQALAVGRAVAAT-------- 116

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
              GR  V DAPVSG  A A AGTLT++ GGA+ +VA V PLL  +G  + H+G  GAGQ
Sbjct: 117 ---GRAFV-DAPVSGAPAGAEAGTLTVMCGGAAGAVARVRPLLERIGTTILHMGPAGAGQ 172

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           + K  NN++   ++AA+AE   +A A G+ P   A V+ T + R +AA  +
Sbjct: 173 LTKTINNVLYDINIAALAEVLPMAVAMGLDPDQVAQVVTTGTSRSYAAQYF 223

[210][TOP]
>UniRef100_Q1VBB5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Vibrio alginolyticus
           12G01 RepID=Q1VBB5_VIBAL
          Length = 298

 Score =  106 bits (265), Expect = 9e-22
 Identities = 66/172 (38%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLP++  V +       +      G +LID STI PA +R L    A+ +G      
Sbjct: 61  VVTMLPASQHVQSVYLGQDGILDSVESGTLLIDSSTIDPATAR-LVGEKASQLG------ 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +  +DAPVSGG A AAAGTLT IVGG+ ++      +LS MG+ + H G  GAGQ
Sbjct: 114 -----ISFVDAPVSGGVAGAAAGTLTFIVGGSQENFVQAKAVLSHMGKNIFHAGDAGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  M+   EA  L    G+ P   + ++  SSGR WA ++Y+
Sbjct: 169 VAKICNNMMLGILMSGTCEALNLGMENGLDPKVLSDIMLQSSGRNWALELYN 220

[211][TOP]
>UniRef100_C1AW59 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodococcus opacus B4
           RepID=C1AW59_RHOOB
          Length = 299

 Score =  106 bits (264), Expect = 1e-21
 Identities = 67/164 (40%), Positives = 85/164 (51%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLPS   V      +   A  G + ID STI  A++RA             D+    
Sbjct: 62  VITMLPSGKHVLGLYAEILSAAKPGTLFIDSSTIDVADARA-----------AHDEAVKA 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
           G   V DAPVSGG   A AGTL  +VGGA+D   +  PLL +MG+ V H G  G GQ  K
Sbjct: 111 GHRSV-DAPVSGGVVGATAGTLAFMVGGAADDFESAKPLLDVMGKKVVHCGDPGNGQAAK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM AV+EA  L    G+       V + +SG+CWA
Sbjct: 170 ICNNMILGVSMIAVSEAFVLGEKLGLSNQALFDVASNASGQCWA 213

[212][TOP]
>UniRef100_B6JHU8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Oligotropha
           carboxidovorans OM5 RepID=B6JHU8_OLICO
          Length = 295

 Score =  106 bits (264), Expect = 1e-21
 Identities = 67/168 (39%), Positives = 87/168 (51%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+ A V +    + PR   G ++ID STI  A   AL A   A   G        
Sbjct: 61  VITMLPAGAHVLSVWREIVPRLARGTLVIDCSTIDVAS--ALQAHELATAAG-------- 110

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGGT  A   TLT + GG   + AA  P+L  MG + +H G  GAGQ  K
Sbjct: 111 --LRSVDAPVSGGTIGAKNATLTFMAGGEPKAFAAAQPILEKMGAKIIHCGGAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  V EA +L    G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGISMIGVCEAFSLGERLGLSHQALFDVASTSSGQCWSLTSY 216

[213][TOP]
>UniRef100_B6IMT5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodospirillum centenum
           SW RepID=B6IMT5_RHOCS
          Length = 297

 Score =  106 bits (264), Expect = 1e-21
 Identities = 69/172 (40%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALA---PRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           A++TMLP+   V       A    R   G +LID STI    +RA+A           D 
Sbjct: 62  AVVTMLPAGPHVRGVYLGEAGVIARVRPGTLLIDSSTIDVETARAVA-----------DA 110

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
            G  G   ++DAPVSGGT  A AGTLT +VGG+  +     P+L +MG+  VH G  G G
Sbjct: 111 AGQAGH-DMVDAPVSGGTGGATAGTLTFMVGGSGTAFDRARPILEVMGKTIVHAGGPGTG 169

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           Q  K  NN++LG SM AV EA ALA   G+       + + SSG+CW+   Y
Sbjct: 170 QAAKICNNMILGISMIAVGEAFALADKLGLERQKLFDISSKSSGQCWSLTSY 221

[214][TOP]
>UniRef100_B1LX52 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Methylobacterium
           radiotolerans JCM 2831 RepID=B1LX52_METRJ
          Length = 297

 Score =  106 bits (264), Expect = 1e-21
 Identities = 68/168 (40%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V      L    P G +LID ST+   ES   A  +AA  G         
Sbjct: 62  VVTMLPAGRHVVEVWTQLVEALPAGTLLIDSSTVD-VESARKAHALAAARG--------- 111

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVVK 381
                +DAPVSGGT  A AGTLT + GGA  +     PLL  MG+ V H G  GAGQ  K
Sbjct: 112 --CLSVDAPVSGGTGGAKAGTLTFMAGGAEAAFDRAEPLLKAMGKNVFHCGDAGAGQAAK 169

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SM  V+EA AL    G+       V + SSG+CW+   Y
Sbjct: 170 ICNNMILGISMIGVSEAFALGEKLGLSHQALYDVASVSSGQCWSLTTY 217

[215][TOP]
>UniRef100_A9WI89 6-phosphogluconate dehydrogenase NAD-binding n=2 Tax=Chloroflexus
           RepID=A9WI89_CHLAA
          Length = 289

 Score =  106 bits (264), Expect = 1e-21
 Identities = 66/155 (42%), Positives = 83/155 (53%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           LI ML  + AVA  L  L P    G ++IDM +  P  S+  A  +A        + G G
Sbjct: 57  LILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLA--------NRGIG 108

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPVHVGACGAGQVVKA 384
                +DAPVSGG   AAAGTL I+VGG +  V    P+L  +GRP HVG  GAG  VK 
Sbjct: 109 W----VDAPVSGGPEGAAAGTLAIMVGGTASDVERAEPILRALGRPTHVGPPGAGHTVKV 164

Query: 385 ANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLA 489
            N L++G ++ AVAEA  LA A G+ P      LA
Sbjct: 165 INQLIVGLTIQAVAEAMVLAEAYGIDPALLRTALA 199

[216][TOP]
>UniRef100_C4WEB1 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ochrobactrum intermedium
           LMG 3301 RepID=C4WEB1_9RHIZ
          Length = 296

 Score =  106 bits (264), Expect = 1e-21
 Identities = 69/169 (40%), Positives = 92/169 (54%), Gaps = 2/169 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   V A    +AP A   ++ ID STI   +S   A  +AA  G         
Sbjct: 61  VITMLPAGKHVLAVYEDIAPTARKDSLFIDCSTID-VDSARKAHELAASHG--------- 110

Query: 205 GRVHV-LDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIM-GRPVHVGACGAGQVV 378
              H+ +DAPVSGGT  A+AGTLT + GG+ ++     P+L  M G+ VH G  GAGQ  
Sbjct: 111 ---HLSIDAPVSGGTGGASAGTLTFMAGGSDEAFRRGEPILQPMAGKIVHCGGDGAGQAA 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LG SM  V+EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 168 KICNNMILGISMIGVSEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTY 216

[217][TOP]
>UniRef100_A3SR62 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseovarius nubinhibens
           ISM RepID=A3SR62_9RHOB
          Length = 290

 Score =  106 bits (264), Expect = 1e-21
 Identities = 66/168 (39%), Positives = 87/168 (51%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   +      + P    GAV +D ST+  A +RA+A           +D    
Sbjct: 55  VITMLPNGDILRKVAAEIIPAMSKGAVFLDCSTVDVASARAVA-----------EDAQKA 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
           G +  LDAPVSGG   A+ GTLT +VGG     A   PL  IMG + VH G  G GQ  K
Sbjct: 104 G-LSALDAPVSGGIGGASGGTLTFMVGGDDAGFATAKPLFDIMGQKAVHCGPSGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQAMFDVVSTSSGYSWSINAY 210

[218][TOP]
>UniRef100_C1C2H0 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Caligus
           clemensi RepID=C1C2H0_9MAXI
          Length = 324

 Score =  106 bits (264), Expect = 1e-21
 Identities = 72/171 (42%), Positives = 95/171 (55%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPR-APVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           LITMLP+   V +   + A   A  GA+ ID STI P+ S+ LA  V+        DG +
Sbjct: 87  LITMLPNNEIVTSIYSSSALGVARKGALFIDCSTISPSLSQKLAKSVSE-----KSDGSA 141

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSV-AAVTPLLSIMGRPV-HVGACGAGQV 375
                 +DAPVSGG  AA +GTLTI+VG  SD+V +     L  +GR V H G  G GQ 
Sbjct: 142 -----FVDAPVSGGVNAANSGTLTIMVGAESDAVFSKAKSALDAVGRNVIHCGGVGTGQA 196

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           VK  NN++L  SM   +EA  L    G+     A +L+TS+GRCW+ D Y+
Sbjct: 197 VKLCNNMLLAISMIGTSEAMNLGENLGLDVKLLASILSTSTGRCWSVDTYN 247

[219][TOP]
>UniRef100_UPI0001AEE93E 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Streptomyces albus J1074
           RepID=UPI0001AEE93E
          Length = 263

 Score =  105 bits (263), Expect = 2e-21
 Identities = 64/167 (38%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           ++TMLP+   V      +   A  G + +D STI  A++RA   R  A            
Sbjct: 27  VLTMLPAGGHVLGLYDEVLTAARPGTLFVDCSTIDVADARAAHERAVAA----------- 75

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
             +  +DAPVSGG   A A TLT++ GG     A   PLL  MG+  VH G  GAGQ  K
Sbjct: 76  -GMRAVDAPVSGGVVGAEAATLTLMAGGGEAEFAEARPLLEAMGKKAVHCGGPGAGQAAK 134

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
             NN++LG SM AV+EA  L  + G+       V +T+SG+CWA  V
Sbjct: 135 ICNNMILGISMIAVSEAFVLGESLGLSHQALYDVASTASGQCWALSV 181

[220][TOP]
>UniRef100_B4RB38 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Phenylobacterium
           zucineum HLK1 RepID=B4RB38_PHEZH
          Length = 298

 Score =  105 bits (263), Expect = 2e-21
 Identities = 72/170 (42%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATL-HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGG 198
           A+ITMLP+   V +     + P AP  A+LID STI    +RA+A +  A          
Sbjct: 60  AVITMLPAGPHVRSVYAEQVLPHAPKSALLIDCSTIDVESARAVAGQAKA---------- 109

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
            G R    DAPVSGGTAAA AGTL  +VG      A V  +++ M R  +  G  GAGQ 
Sbjct: 110 QGFRF--ADAPVSGGTAAAEAGTLAFMVGCDEADFAEVERIIAPMSRATIRAGDHGAGQA 167

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN+VLG SM  V EA ALA   G+ PV    + + SSG+CW+   Y
Sbjct: 168 AKICNNMVLGISMIGVCEALALAEKLGLDPVKFYEISSQSSGQCWSLTSY 217

[221][TOP]
>UniRef100_A6V1M4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           PA7 RepID=A6V1M4_PSEA7
          Length = 298

 Score =  105 bits (263), Expect = 2e-21
 Identities = 70/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGDDGLLARLAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPILENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA +VY+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVRNGLDPAVLSEVMKQSSGGNWALNVYN 220

[222][TOP]
>UniRef100_A4SM69 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Aeromonas salmonicida
           subsp. salmonicida A449 RepID=A4SM69_AERS4
          Length = 301

 Score =  105 bits (263), Expect = 2e-21
 Identities = 66/175 (37%), Positives = 92/175 (52%), Gaps = 7/175 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA------LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           +I+MLP+   V A   A      L    P GA++ID STI  A +R +            
Sbjct: 56  VISMLPAGEHVRALWLAGNGGQDLLAALPTGALVIDCSTIDVASARQVG----------- 104

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACG 363
            +      +  +DAPVSGG A A+AGTLT IVGG      A +P+L+ MG+ + H GA G
Sbjct: 105 -EAAKARGIRFVDAPVSGGVAGASAGTLTFIVGGELADFEAASPILAHMGQNLFHAGALG 163

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           AGQ+ K  NN++L   MA  AEA AL    G+ P   + ++  SSG  W+ + Y+
Sbjct: 164 AGQIAKMCNNMLLAIHMAGTAEALALGVKEGLDPSVLSTIMGKSSGNNWSLERYN 218

[223][TOP]
>UniRef100_A9GST5 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Roseobacter litoralis
           Och 149 RepID=A9GST5_9RHOB
          Length = 640

 Score =  105 bits (263), Expect = 2e-21
 Identities = 66/168 (39%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +++MLP+ A +     A+ P    GA+ +D ST+    +RA+A            D    
Sbjct: 405 VLSMLPNGAILRDVAAAVLPVMKPGALFLDCSTVDVDSARAVAR-----------DAQDA 453

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
           G + V DAPVSGG   AAAGTLT + GG++ +     PL  IMG + VH G  GAGQ  K
Sbjct: 454 GLLFV-DAPVSGGIGGAAAGTLTFMAGGSAAAFETAQPLFDIMGQKAVHCGDAGAGQAAK 512

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M A  EA ALA   G+       V++TSSG  W+ + Y
Sbjct: 513 ICNNMILGATMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWSMNAY 560

[224][TOP]
>UniRef100_A3JFX4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Marinobacter sp. ELB17
           RepID=A3JFX4_9ALTE
          Length = 295

 Score =  105 bits (263), Expect = 2e-21
 Identities = 67/172 (38%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       L    P G ++ID STI P  ++ +AA+            
Sbjct: 61  VITMLPAGQHVEAVYLGAEGLLAALPEGTLVIDSSTIAPETAKKVAAQA----------- 109

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
            S  +V  LDAPVSGG   A AGTLT I GG+    AA  P+L  MG+ +   G  G+GQ
Sbjct: 110 -SEHKVRFLDAPVSGGVGGAKAGTLTFICGGSEVDYAAAQPILQDMGKNIFRAGEHGSGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++L   MA  +EA AL    G+ P   + ++  SSG  WA +VY+
Sbjct: 169 VAKICNNMLLAILMAGTSEALALGVKNGLDPAVLSEIMKQSSGGNWALNVYN 220

[225][TOP]
>UniRef100_B6A3K7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhizobium leguminosarum
           bv. trifolii WSM2304 RepID=B6A3K7_RHILW
          Length = 293

 Score =  105 bits (262), Expect = 2e-21
 Identities = 66/170 (38%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDGG 198
           +ITMLP    V      +   A    ++ID STI    SR     A+ A+ +        
Sbjct: 61  VITMLPQGRHVLTAWTDILQTAAQNTLVIDCSTIDVESSRKAHEMAKAASCLS------- 113

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
                  LDAPVSGGT  A AGTLT + GG+ ++ A   P+L  MG+  VH G  GAGQ 
Sbjct: 114 -------LDAPVSGGTGGATAGTLTFMAGGSDEAFARAKPILEAMGKKIVHCGEAGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+ + Y
Sbjct: 167 AKICNNMILGISMVGVCEAFVLAEKLGLSHQALFDVASTSSGQCWSINTY 216

[226][TOP]
>UniRef100_A6VAN4 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           PA7 RepID=A6VAN4_PSEA7
          Length = 298

 Score =  105 bits (262), Expect = 2e-21
 Identities = 70/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP++  V         L      GA++++ STI PA +R + A  AA   G     
Sbjct: 61  VISMLPASQHVEGLYLGDDGLLMHIAAGALVLECSTIAPASARKVHA--AARERG----- 113

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGGTA AAAGTLT +VGG ++++    PL   MGR + H G  GAGQ
Sbjct: 114 -----LAMLDAPVSGGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN +L   M   AEA AL  A G+     A ++  SSG  WA +VY+
Sbjct: 169 VAKVCNNQLLAVLMIGTAEAMALGVANGLEAKVLAEIMRRSSGGNWALEVYN 220

[227][TOP]
>UniRef100_A4F9Q6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Saccharopolyspora
           erythraea NRRL 2338 RepID=A4F9Q6_SACEN
          Length = 295

 Score =  105 bits (262), Expect = 2e-21
 Identities = 69/165 (41%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
 Frame = +1

Query: 22  ALITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           A+ITMLP    +      +   A    +LID ST+  A++R    R A        + G 
Sbjct: 60  AVITMLPGGKQLLECYDQVLGAASPETLLIDSSTVDVADARKAHERAA--------EAGF 111

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVV 378
           G     +DAPVSGGTA A AGTLT +VGG  ++     P+L  M R V H G  G GQV 
Sbjct: 112 GS----VDAPVSGGTAGAEAGTLTFMVGGTEENYNRAQPVLEPMARKVIHCGGPGNGQVT 167

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
           K  NNLVLGASM AV+EA  L    GV       V++ S+G+CW+
Sbjct: 168 KMCNNLVLGASMIAVSEAFVLGERLGVSHQALYDVVSISTGQCWS 212

[228][TOP]
>UniRef100_UPI00016E742C UPI00016E742C related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E742C
          Length = 329

 Score =  105 bits (261), Expect = 3e-21
 Identities = 67/172 (38%), Positives = 89/172 (51%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  V       + +  +   G++LID STI P  S+ +AA  A  MG      
Sbjct: 92  IITMLPSSPNVMEVYTGSNGILKKVKKGSLLIDSSTIDPTVSKEMAA-AAEKMGAV---- 146

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA++  LT +VGGA +   A   LLS MG   V+ G  G GQ
Sbjct: 147 -------FMDAPVSGGVGAASSAKLTFMVGGAEEEFTAAKELLSCMGANVVYCGQVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L   M   AE   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAIGMIGTAETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 251

[229][TOP]
>UniRef100_Q1KKZ7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Takifugu rubripes
           RepID=Q1KKZ7_TAKRU
          Length = 325

 Score =  105 bits (261), Expect = 3e-21
 Identities = 67/172 (38%), Positives = 89/172 (51%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLPS+  V       + +  +   G++LID STI P  S+ +AA  A  MG      
Sbjct: 87  IITMLPSSPNVMEVYTGSNGILKKVKKGSLLIDSSTIDPTVSKEMAA-AAEKMGAV---- 141

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA++  LT +VGGA +   A   LLS MG   V+ G  G GQ
Sbjct: 142 -------FMDAPVSGGVGAASSAKLTFMVGGAEEEFTAAKELLSCMGANVVYCGQVGTGQ 194

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L   M   AE   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 195 AAKICNNMLLAIGMIGTAETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 246

[230][TOP]
>UniRef100_B5X3N8 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1 Tax=Salmo
           salar RepID=B5X3N8_SALSA
          Length = 332

 Score =  105 bits (261), Expect = 3e-21
 Identities = 65/172 (37%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           ++TMLPS+  V       + +  +   G++LID STI PA S+ +A   A  MG      
Sbjct: 92  IVTMLPSSPNVIEVYTGPNGILKKVKKGSLLIDSSTIDPAVSKEMAV-AAEKMGAV---- 146

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQ 372
                   +DAPVSGG  AA++G LT +VGG  +   A   LL+ MG   V+ GA G GQ
Sbjct: 147 -------FMDAPVSGGVGAASSGKLTFMVGGVEEEFTAAQELLTCMGANVVYCGAVGTGQ 199

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
             K  NN++L   M   +E   L    G+ P   A +L  SSGRCW++D Y+
Sbjct: 200 AAKICNNMLLAIGMIGTSETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYN 251

[231][TOP]
>UniRef100_Q02R40 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           UCBPP-PA14 RepID=Q02R40_PSEAB
          Length = 298

 Score =  105 bits (261), Expect = 3e-21
 Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGADGLLARVAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPILENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA ++Y+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYN 220

[232][TOP]
>UniRef100_B7VAL2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           LESB58 RepID=B7VAL2_PSEA8
          Length = 298

 Score =  105 bits (261), Expect = 3e-21
 Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPILENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA ++Y+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYN 220

[233][TOP]
>UniRef100_B1MKI2 Probable 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Mycobacterium
           abscessus ATCC 19977 RepID=B1MKI2_MYCA9
          Length = 293

 Score =  105 bits (261), Expect = 3e-21
 Identities = 68/164 (41%), Positives = 82/164 (50%), Gaps = 1/164 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP  A V A    L P A  G + ID ST+  A++RA  A  AA   G        
Sbjct: 61  VITMLPKGAHVLAAYEDLLPAARPGTLFIDSSTVDVADARA--AHEAATAAGH------- 111

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
                 DAPVSGG   A A TLT +VG       A  P+L  MG R VH G  G GQ  K
Sbjct: 112 ---RFADAPVSGGVPGATAATLTFMVGADDAVFVAAEPILDAMGKRVVHCGGPGVGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
             NN++LG SM A++EA  L    G+       V A +SG+CWA
Sbjct: 169 ICNNMILGVSMIAISEAFVLGEKLGLSHQALFDVAANASGQCWA 212

[234][TOP]
>UniRef100_A9WQX6 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Renibacterium
           salmoninarum ATCC 33209 RepID=A9WQX6_RENSM
          Length = 294

 Score =  105 bits (261), Expect = 3e-21
 Identities = 67/170 (39%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
 Frame = +1

Query: 10  PPPIALITMLPSTAAVAATLHA-LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGD 186
           P    ++TM PS   +    +  L   AP G + +D STI   E+RA AA +A   G   
Sbjct: 55  PDAEVVLTMFPSGKHLLDAYNGGLLAAAPAGPLFLDCSTINVDEARA-AAELAVAAGH-- 111

Query: 187 DDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACG 363
                       DAPVSGG   A AG+LT +VG +++  A V P+L++MG R VH GA G
Sbjct: 112 ---------RAADAPVSGGVVGAEAGSLTFMVGASAEEFAFVQPVLNVMGKRAVHCGANG 162

Query: 364 AGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWA 513
           AGQ  K  NN++LG SM   AEA  L    G+       V++T+SG+CW+
Sbjct: 163 AGQAAKICNNMLLGISMIGAAEAFVLGEKLGLEHQALYDVISTASGQCWS 212

[235][TOP]
>UniRef100_A7HX74 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Parvibaculum
           lavamentivorans DS-1 RepID=A7HX74_PARL1
          Length = 296

 Score =  105 bits (261), Expect = 3e-21
 Identities = 68/173 (39%), Positives = 88/173 (50%), Gaps = 6/173 (3%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTI--PPAESRALAARVAAVMGGGDD 189
           ++TMLP+   V +       L   A  G V ID STI  P A     AA  A +M     
Sbjct: 61  VVTMLPAGEHVRSVYLGEGGLLSVAAKGTVFIDSSTIDVPSARETIAAAEKAGMM----- 115

Query: 190 DGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGA 366
                    ++DAPVSGG   A AGTLT + GG  D+     PLL IMG+ + H GA G 
Sbjct: 116 ---------MIDAPVSGGVGGAEAGTLTFMAGGTVDAFEKAKPLLEIMGKNIFHAGAAGN 166

Query: 367 GQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           GQV K  NN++LG SM  V+EA  L    G+   T   + +T+SG+CW+   Y
Sbjct: 167 GQVAKVCNNMILGISMIGVSEAFVLGEKLGLDAQTLFDISSTASGQCWSMTSY 219

[236][TOP]
>UniRef100_A3LE29 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           2192 RepID=A3LE29_PSEAE
          Length = 298

 Score =  105 bits (261), Expect = 3e-21
 Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPILENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA ++Y+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYN 220

[237][TOP]
>UniRef100_A3KXJ7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           C3719 RepID=A3KXJ7_PSEAE
          Length = 298

 Score =  105 bits (261), Expect = 3e-21
 Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPILENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA ++Y+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYN 220

[238][TOP]
>UniRef100_C1BUI0 3-hydroxyisobutyrate dehydrogenase, mitochondrial n=1
           Tax=Lepeophtheirus salmonis RepID=C1BUI0_9MAXI
          Length = 322

 Score =  105 bits (261), Expect = 3e-21
 Identities = 72/171 (42%), Positives = 95/171 (55%), Gaps = 3/171 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALA-PRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           LITMLP+   V +   + A   A   AV ID STI P+ S+ LA  V+      D D  S
Sbjct: 87  LITMLPNNDIVQSVYSSTALDNARKSAVFIDCSTISPSISQKLANEVS------DRDKNS 140

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSV-AAVTPLLSIMGRPV-HVGACGAGQV 375
                 +DAPVSGG  AA AGTLTI+VG  +  V +    +L  +G+ V H G  G+GQ 
Sbjct: 141 S----FVDAPVSGGVNAANAGTLTIMVGAKNKDVFSKAKNILEAVGKNVIHCGDVGSGQA 196

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           VK  NN++L  SM   +EA  L    G+ P   A VL++S+GRCW+ D Y+
Sbjct: 197 VKLCNNMLLAISMIGTSEAMNLGKNLGLDPNLLASVLSSSTGRCWSVDTYN 247

[239][TOP]
>UniRef100_Q2RTB2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodospirillum rubrum
           ATCC 11170 RepID=Q2RTB2_RHORT
          Length = 296

 Score =  104 bits (260), Expect = 3e-21
 Identities = 70/172 (40%), Positives = 92/172 (53%), Gaps = 5/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHA----LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDD 192
           +ITMLP+   V A        +A  AP G +LID STI  A +RA+A   AA   G    
Sbjct: 61  VITMLPAGTIVRAVYEGPGGVIANAAP-GTLLIDCSTIDVASARAVAE--AATAAG---- 113

Query: 193 GGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAG 369
                 + ++DAPVSGG A AAA TLT +VGG  ++  A  P+L+ MG   VH GA G G
Sbjct: 114 ------LSMVDAPVSGGVAGAAAATLTFMVGGPPETFEAARPILAAMGGTIVHAGAAGTG 167

Query: 370 QVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           Q  K  NN++LG SM    EA  LA   G+       + + +SG+CW+   Y
Sbjct: 168 QAAKICNNMLLGISMIGTCEAFMLAKRLGLDAQKLFDISSKASGQCWSLTSY 219

[240][TOP]
>UniRef100_Q2K0S1 Putative 3-hydroxyisobutyrate dehydrogenase protein n=1
           Tax=Rhizobium etli CFN 42 RepID=Q2K0S1_RHIEC
          Length = 293

 Score =  104 bits (260), Expect = 3e-21
 Identities = 66/170 (38%), Positives = 85/170 (50%), Gaps = 3/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRAL--AARVAAVMGGGDDDGG 198
           +ITMLP    V      +      G ++ID STI    SR     A+ A  +        
Sbjct: 61  VITMLPQGRHVLTAWADILQSTAQGTLVIDCSTIDVESSRKAHEMAKTAGCLS------- 113

Query: 199 SGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQV 375
                  LDAPVSGGT  A+AGTLT + GG+ D+     P+L  MG+  VH G  GAGQ 
Sbjct: 114 -------LDAPVSGGTGGASAGTLTFMAGGSDDAFLKGKPILEAMGKKIVHCGEAGAGQA 166

Query: 376 VKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
            K  NN++LG SM  V EA  LA   G+       V +TSSG+CW+ + Y
Sbjct: 167 AKICNNMILGISMVGVCEAFVLAEKLGLSHQALFDVASTSSGQCWSINTY 216

[241][TOP]
>UniRef100_C5CR26 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Variovorax paradoxus
           S110 RepID=C5CR26_VARPS
          Length = 300

 Score =  104 bits (260), Expect = 3e-21
 Identities = 65/176 (36%), Positives = 90/176 (51%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAP-------VGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +I+MLP++A V           P        G ++ID STI  A SR +A          
Sbjct: 60  VISMLPASAHVEGLFLGSGGSKPGLLDSIRAGTLVIDSSTIAAATSRKVA---------- 109

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGAC 360
             D  +   + ++DAPVSGGT  A AGTLT +VGG +D +    P+L  MG  + H G  
Sbjct: 110 --DAAAAKGIAMIDAPVSGGTGGAIAGTLTFMVGGEADDLERARPVLEKMGANIFHAGGV 167

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           GAGQ  K  NN++LG  M   +EA AL  A G+ P   + ++  SSG  WA + Y+
Sbjct: 168 GAGQTAKICNNMLLGILMIGTSEALALGVANGLDPKVLSEIMRRSSGGNWALEKYN 223

[242][TOP]
>UniRef100_A5V3Z9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Sphingomonas wittichii
           RW1 RepID=A5V3Z9_SPHWW
          Length = 296

 Score =  104 bits (260), Expect = 3e-21
 Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 2/169 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL-HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           +++MLP+   V A   + +    P  A+LID STI  A +RA+    AA           
Sbjct: 61  VVSMLPAGQHVRAVYENDVFGSVPPSALLIDCSTIDVASARAVNGAAAAK---------- 110

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVV 378
              + ++DAPVSGG AAA  GTLT +VGG+++  A   P+L++MG+ V H G  G+GQ  
Sbjct: 111 --GLAMVDAPVSGGIAAANGGTLTFMVGGSAEHFARAEPVLALMGKAVIHAGGAGSGQAA 168

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
           K  NN++LGA+M A  EA ALA+  G+   T   + + +SG+ W+   Y
Sbjct: 169 KIVNNMILGATMVATCEAFALASKLGLDLQTFYDISSKASGQSWSMTSY 217

[243][TOP]
>UniRef100_A1U2I9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Marinobacter aquaeolei
           VT8 RepID=A1U2I9_MARAV
          Length = 295

 Score =  104 bits (260), Expect = 3e-21
 Identities = 67/172 (38%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +ITMLP+   V A       L    P G ++ID STI P  SRA+A   AA         
Sbjct: 61  VITMLPAGKHVEAVYLGEDGLLAALPAGTLVIDSSTIAPETSRAVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                +  +DAPVSGG   A AGTLT I GG   +     P+L  MG+ + H G  GAGQ
Sbjct: 113 ----DLAFIDAPVSGGVGGATAGTLTFICGGEVATYNKARPVLEAMGKNIFHAGPHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++L   MA  +EA AL    G+ P   + ++  SSG  WA ++Y+
Sbjct: 169 VAKICNNMMLAILMAGTSEALALGVKNGLDPAVLSEIMKQSSGGNWALNLYN 220

[244][TOP]
>UniRef100_A3VDC7 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Rhodobacterales
           bacterium HTCC2654 RepID=A3VDC7_9RHOB
          Length = 290

 Score =  104 bits (260), Expect = 3e-21
 Identities = 64/168 (38%), Positives = 86/168 (51%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   + A    + P    GA+  D ST+    +RA+A            D    
Sbjct: 55  VITMLPNGKILRAVADEIVPAMDKGALFADCSTVDVESARAVA------------DQAME 102

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AA GTLT + GG+ ++   V PLL IMG + VH G  G GQ  K
Sbjct: 103 AGLLAIDAPVSGGITGAANGTLTFMAGGSEEAFDKVKPLLDIMGQKAVHCGPSGNGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LGA+M    EA ALA   G+       V++TSSG  W  + Y
Sbjct: 163 ICNNMILGATMIVTCEAFALADKLGLDRQAMFDVVSTSSGYSWTMNAY 210

[245][TOP]
>UniRef100_B9GH10 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GH10_POPTR
          Length = 347

 Score =  104 bits (260), Expect = 3e-21
 Identities = 70/176 (39%), Positives = 92/176 (52%), Gaps = 8/176 (4%)
 Frame = +1

Query: 25  LITMLPSTAAVA-------ATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGG 183
           +ITMLPS++ V          L       P   +LID STI P  SR ++  V+  +   
Sbjct: 97  VITMLPSSSHVLDVYTGPNGLLRCANLMRP--QLLIDSSTIDPQTSRKVSVAVSNCILKE 154

Query: 184 DDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGR-PVHVGAC 360
             D     +  +LDAPVSGG  AA AGTLT +VGG+ D+  A  PL   MG+  ++ G  
Sbjct: 155 KKDHWE--KPVMLDAPVSGGVLAAEAGTLTFMVGGSEDAYLAAKPLFLSMGKNAIYCGGA 212

Query: 361 GAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           G G   K  NNL L  SM  V+EA  L  + G+   T   VL TSS RCW++D Y+
Sbjct: 213 GTGSAAKICNNLALAVSMLGVSEAFVLGQSLGISAGTLTKVLNTSSARCWSSDSYN 268

[246][TOP]
>UniRef100_B4LJ32 GJ22064 n=1 Tax=Drosophila virilis RepID=B4LJ32_DROVI
          Length = 322

 Score =  104 bits (260), Expect = 3e-21
 Identities = 67/170 (39%), Positives = 92/170 (54%), Gaps = 2/170 (1%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHAL-APRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGS 201
           +ITMLP+   V A+   + A       + ID STI P   ++L  R++A           
Sbjct: 88  VITMLPNNDIVDASYEEMTANGVNKNTIFIDSSTIDPNLVKSLQKRISA----------K 137

Query: 202 GGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQVV 378
           G R   +DAPVSGG   A   TLT +VGG      AV  +L  MG+ + H G  G GQ  
Sbjct: 138 GARF--IDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKRITHCGDYGMGQAA 195

Query: 379 KAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           K ANN++L  SM  V+EA  LA   G+ P T A ++ +S+GRCWA++VY+
Sbjct: 196 KLANNMMLAISMIGVSEAMNLAMRLGLNPKTFAEIINSSTGRCWASEVYN 245

[247][TOP]
>UniRef100_P28811 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Pseudomonas aeruginosa
           RepID=MMSB_PSEAE
          Length = 298

 Score =  104 bits (260), Expect = 3e-21
 Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
 Frame = +1

Query: 25  LITMLPSTAAVAATL---HALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDG 195
           +I+MLP+   V +       L  R     +LID STI P  +R +A   AA         
Sbjct: 61  VISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAK-------- 112

Query: 196 GSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRPV-HVGACGAGQ 372
                + +LDAPVSGG   A AGTL+ IVGG ++  A   P+L  MGR + H G  GAGQ
Sbjct: 113 ----GLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQ 168

Query: 373 VVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVYH 528
           V K  NN++LG  MA  AEA AL    G+ P   + V+  SSG  WA ++Y+
Sbjct: 169 VAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYN 220

[248][TOP]
>UniRef100_Q1QWU9 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1QWU9_CHRSD
          Length = 310

 Score =  104 bits (259), Expect = 4e-21
 Identities = 67/175 (38%), Positives = 91/175 (52%), Gaps = 4/175 (2%)
 Frame = +1

Query: 10  PPPIALITMLPSTAAVAATLHA---LAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGG 180
           P     +  LP++A V   +     L  RAP G+V++D ST  PA +R LA +V      
Sbjct: 63  PEADVYLLSLPTSAHVREVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEA--- 119

Query: 181 GDDDGGSGGRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGA 357
                     +  LDAPVSGG A AA+G L +++GG S ++  + P+L  M  R  HVG 
Sbjct: 120 ---------GLEWLDAPVSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGP 170

Query: 358 CGAGQVVKAANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADV 522
            G+G VVK ANN +  A +   AEA  LAA AGV P      L + SGR   ++V
Sbjct: 171 AGSGHVVKLANNYLCAAHLLTTAEAVTLAARAGVDPAACLAGLNSGSGRSAVSEV 225

[249][TOP]
>UniRef100_Q1GHN2 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Ruegeria sp. TM1040
           RepID=Q1GHN2_SILST
          Length = 290

 Score =  104 bits (259), Expect = 4e-21
 Identities = 63/168 (37%), Positives = 86/168 (51%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP+   +      + P    GA  +D ST+    +RA+A + A             
Sbjct: 55  VITMLPNGDILRHVASEIIPAMTNGAAFVDCSTVDVDSARAVAQQAAEA----------- 103

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMG-RPVHVGACGAGQVVK 381
             +  +DAPVSGG   AA GTLT + GG+ ++ A   PL  IMG + VH G  GAGQ  K
Sbjct: 104 -GLLAVDAPVSGGIGGAAGGTLTFMAGGSEEAFAKAAPLFDIMGQKAVHCGDSGAGQAAK 162

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG +M A  EA ALA   G+       V++TSSG  W  + Y
Sbjct: 163 ICNNMILGVTMIATCEAFALADKLGLDRQKMFDVVSTSSGYSWTMNAY 210

[250][TOP]
>UniRef100_A6UHB8 3-hydroxyisobutyrate dehydrogenase n=1 Tax=Sinorhizobium medicae
           WSM419 RepID=A6UHB8_SINMW
          Length = 298

 Score =  104 bits (259), Expect = 4e-21
 Identities = 68/168 (40%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
 Frame = +1

Query: 25  LITMLPSTAAVAATLHALAPRAPVGAVLIDMSTIPPAESRALAARVAAVMGGGDDDGGSG 204
           +ITMLP++A V      L      G +LID STI    +R +                  
Sbjct: 61  VITMLPASAHVLYVWDELLGFVDPGTLLIDSSTIDVESARKVHGLAEKA----------- 109

Query: 205 GRVHVLDAPVSGGTAAAAAGTLTIIVGGASDSVAAVTPLLSIMGRP-VHVGACGAGQVVK 381
                LDAPVSGGTA AA  TLT +VGG+  + +    LL  MG+  VH G  GAGQ  K
Sbjct: 110 -NCPSLDAPVSGGTAGAAGATLTFMVGGSDGAFSRGKHLLEAMGKKIVHCGDAGAGQAAK 168

Query: 382 AANNLVLGASMAAVAEATALAAAAGVPPVTTAVVLATSSGRCWAADVY 525
             NN++LG SMAAV EA  LA   G+       V +TSSG+CW+   Y
Sbjct: 169 ICNNMILGVSMAAVCEAFVLAERLGLSHQALFDVASTSSGQCWSLTTY 216