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[1][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 94.4 bits (233), Expect = 5e-18
Identities = 66/180 (36%), Positives = 91/180 (50%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H Q
Sbjct: 724 GLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQ 783
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E A V+ELK L++ KG PP L+S A
Sbjct: 784 MLRLNEKIEELKAVVEELKSDLSRVKKG----------KPP-------------LKSKNA 820
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K PK +++ + L+ + + ++ K+ D E KEDL+TVALGTSK
Sbjct: 821 DGK----------PK----RNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSK 866
[2][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 92.4 bits (228), Expect = 2e-17
Identities = 62/178 (34%), Positives = 94/178 (52%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 185
L+AKVFRT+NAS+TL LQ GET + +A Y + NK VA LCNH R++ GH QM+
Sbjct: 450 LTAKVFRTYNASITLDNLLQDTTGETTIEIIADYQRANKQVAILCNHQRSVSKGHSAQME 509
Query: 186 KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADE 365
+LE + E ++EL+ L + KG PP++ ++ ++ + T +
Sbjct: 510 RLEGKMQELEEQLEELETDLDRAKKG----------KPPLKDSE-----GKVKRNQTPE- 553
Query: 366 KAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
A E+K AA ++++ K+ DM +K+DL+TVALGTSK
Sbjct: 554 -ALEKKIAA----------------------TKQKIDKMRLDMRVKDDLKTVALGTSK 588
[3][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 92.0 bits (227), Expect = 2e-17
Identities = 60/179 (33%), Positives = 90/179 (50%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM 182
GL+AKVFRT+NAS+TL LQ GET + +A Y + NK VA LCNH R++ GH QM
Sbjct: 319 GLTAKVFRTYNASITLDTLLQDTRGETTIEIIADYQRANKEVAILCNHQRSVSKGHSAQM 378
Query: 183 QKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 362
++LE + E ++EL+ L + +G PP+
Sbjct: 379 ERLELKMQELEEQLEELETDLDRAKRG----------KPPL------------------- 409
Query: 363 EKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K E K + ++ + L+ + +++ K+ DM +K+DL+TVALGTSK
Sbjct: 410 -KDSEGK---------VKRNQTPEALEKKIASTTQKIDKMRLDMRVKDDLKTVALGTSK 458
[4][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 90.5 bits (223), Expect = 7e-17
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q
Sbjct: 327 GLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQ 386
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL R E +KELK L + KG PP+E
Sbjct: 387 IEKLTARIEELKEVLKELKTNLDRAKKG----------KPPLE----------------- 419
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+D K+ +S+ + + + + ++ K+ DM KEDL+TVALGTSK
Sbjct: 420 ---------GSDGKKI---RSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSK 467
[5][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 90.5 bits (223), Expect = 7e-17
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q
Sbjct: 209 GLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQ 268
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL R E +KELK L + KG PP+E
Sbjct: 269 IEKLTARIEELKEVLKELKTNLDRAKKG----------KPPLE----------------- 301
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+D K+ +S+ + + + + ++ K+ DM KEDL+TVALGTSK
Sbjct: 302 ---------GSDGKKI---RSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSK 349
[6][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 90.5 bits (223), Expect = 7e-17
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q
Sbjct: 83 GLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQ 142
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL R E +KELK L + KG PP+E
Sbjct: 143 IEKLTARIEELKEVLKELKTNLDRAKKG----------KPPLE----------------- 175
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+D K+ +S+ + + + + ++ K+ DM KEDL+TVALGTSK
Sbjct: 176 ---------GSDGKKI---RSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSK 223
[7][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 90.5 bits (223), Expect = 7e-17
Identities = 62/185 (33%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ------GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPS 164
GL+AKVFRT+NAS+TL E ++ G V +KV Y NK VA +CNH RT+
Sbjct: 579 GLTAKVFRTYNASITLDEMVRCKLLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSK 638
Query: 165 GHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
H QM +L + E +KEL+ L + NKG PP++ + P +
Sbjct: 639 SHSAQMVRLNEKIEELKGLLKELQEDLTRVNKG----------KPPLKNSDGKPKR---- 684
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
+ K + K + K+ R + + + ++ K+ D E KEDL+TVA
Sbjct: 685 ---NLNLKRYKGKLLKLIQKLRKWSETRRLSVTKKIAQTNTKIEKMERDKETKEDLKTVA 741
Query: 525 LGTSK 539
LGTSK
Sbjct: 742 LGTSK 746
[8][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 90.5 bits (223), Expect = 7e-17
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q
Sbjct: 729 GLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQ 788
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL R E +KELK L + KG PP+E
Sbjct: 789 IEKLTARIEELKEVLKELKTNLDRAKKG----------KPPLE----------------- 821
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+D K+ +S+ + + + + ++ K+ DM KEDL+TVALGTSK
Sbjct: 822 ---------GSDGKKI---RSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSK 869
[9][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 89.4 bits (220), Expect = 2e-16
Identities = 62/180 (34%), Positives = 90/180 (50%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + V +KV Y + NK VA +CNH RT+ H Q
Sbjct: 707 GLTAKVFRTYNASITLDEKLYEETEDGDVAEKVVIYQRANKEVAIICNHQRTISKSHGAQ 766
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M KL + E A +KELK L + KG PP++ A
Sbjct: 767 MSKLIEKIEELKATLKELKTDLDRAKKG----------KPPLK---------------DA 801
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K + +++ + ++ + +R+ K+ +M+ KEDL+TVALGTSK
Sbjct: 802 DGKQK--------------RNLSPENIEKKIASTNQRIEKMELNMKTKEDLKTVALGTSK 847
[10][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 88.6 bits (218), Expect = 3e-16
Identities = 60/180 (33%), Positives = 91/180 (50%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GLSAKVFRT+NAS+TL E L + G V+ KVA Y NK VA +CNH R++ H Q
Sbjct: 725 GLSAKVFRTYNASITLDEMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRSVSKSHSTQ 784
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L+ + + +++ELK L++ KG PP++ +
Sbjct: 785 MMRLDEKINKLKNFIEELKTDLSRAKKG----------KPPLK---------------GS 819
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K + ++M + ++ + + ++ K+ D E KEDL+TVALGTSK
Sbjct: 820 DGKTK--------------RNMNPEAIEKKIAQTNVKIEKMERDKETKEDLKTVALGTSK 865
[11][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 88.2 bits (217), Expect = 3e-16
Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + V +K+ YN+ NK VA +CNH RT+ H Q
Sbjct: 693 GLTAKVFRTYNASITLDEKLYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQ 752
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E + +KELK L + KG PP++ A
Sbjct: 753 MSRLTEKIEELKSTLKELKTDLDRAKKG----------KPPLK---------------GA 787
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K + +S+ + ++ + +++ K+ M+ KEDL+TVALGTSK
Sbjct: 788 DGKQK--------------RSLTPEAIEKKIATTNQKIEKMEMAMKTKEDLKTVALGTSK 833
[12][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 87.4 bits (215), Expect = 6e-16
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H Q
Sbjct: 743 GLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQ 802
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E ++ELK L++ KG PP S A
Sbjct: 803 MSRLNEKIDELKTAMEELKTDLSRVKKG----------KPP---------------SKGA 837
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K PK +++ + L+ + + ++ K+ D E KEDL+TVALGTSK
Sbjct: 838 DGK----------PK----RNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSK 883
[13][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 87.0 bits (214), Expect = 8e-16
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + G +K+ Y NK VA +CNH R++ H Q
Sbjct: 699 GLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQ 758
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E + ELK LA+ KG KP + +S
Sbjct: 759 MSRLSEKMRELQGVLDELKTDLARAKKG----------------------KPPLKDS--- 793
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K PK K+M + L+ + + ++ K+ DM+ KEDL+TVALGTSK
Sbjct: 794 DGK----------PK----KNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSK 839
[14][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 87.0 bits (214), Expect = 8e-16
Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + G +K+ Y NK VA +CNH R++ H Q
Sbjct: 605 GLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQ 664
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E + ELK LA+ KG KP + +S
Sbjct: 665 MSRLSEKMRELQGVLDELKTDLARAKKG----------------------KPPLKDS--- 699
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K PK K+M + L+ + + ++ K+ DM+ KEDL+TVALGTSK
Sbjct: 700 DGK----------PK----KNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSK 745
[15][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 86.3 bits (212), Expect = 1e-15
Identities = 58/180 (32%), Positives = 93/180 (51%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL L + + T+ +K+A Y + NK VA +CNH R++ H+ Q
Sbjct: 737 GLTAKVFRTYNASITLDGILHEETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHESQ 796
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M KL + E + ++ELK L+K KG KP +
Sbjct: 797 MIKLNEKIDELKSQMEELKADLSKAKKG----------------------KP-----LGY 829
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D++ ++++ A + ++ + E ++ K+ D ++KEDL+TVALGTSK
Sbjct: 830 DKEGKQKRNLAP------------EAIEKKIAMVEGKIDKMEMDKKIKEDLKTVALGTSK 877
[16][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 84.7 bits (208), Expect = 4e-15
Identities = 56/180 (31%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + + T+ +K+A Y + NK VA +CNH R++ H Q
Sbjct: 732 GLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQ 791
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E A ELK L+K KG +++
Sbjct: 792 MTRLNEKIDELKAQRDELKADLSKVRKG---------------------------KNLGN 824
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D+ + ++ A + + + + E ++ K+ D ++KEDL+TVALGTSK
Sbjct: 825 DKDGKPKRNLAP------------EAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSK 872
[17][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 84.7 bits (208), Expect = 4e-15
Identities = 58/180 (32%), Positives = 87/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + + V +K YN+ NK VA +CNH RT+ H Q
Sbjct: 676 GLTAKVFRTYNASITLDEKLYEETEDGDVAEKFVIYNQANKQVAIICNHQRTISKSHDAQ 735
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E +KE K L + KG PP++ A
Sbjct: 736 MSRLTEKLEELKGTLKEFKTDLDRAKKG----------KPPLK---------------DA 770
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K + +++ + ++ + +++ K+ M+ KEDL+TVALGTSK
Sbjct: 771 DGKQK--------------RNLTPEAIEKKIATTNQKIEKMELSMKTKEDLKTVALGTSK 816
[18][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 84.7 bits (208), Expect = 4e-15
Identities = 56/180 (31%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + + T+ +K+A Y + NK VA +CNH R++ H Q
Sbjct: 732 GLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQ 791
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E A ELK L+K KG +++
Sbjct: 792 MTRLNEKIDELKAQRDELKADLSKVRKG---------------------------KNLGN 824
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D+ + ++ A + + + + E ++ K+ D ++KEDL+TVALGTSK
Sbjct: 825 DKDGKPKRNLAP------------EAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSK 872
[19][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 84.3 bits (207), Expect = 5e-15
Identities = 69/222 (31%), Positives = 103/222 (46%), Gaps = 43/222 (19%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH RT+ GH
Sbjct: 526 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKILRYNAANRTVAILCNHQRTVTKGHASS 585
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKWNKGGK----------------------------- 269
+QK T R E + W K KR + + +K +
Sbjct: 586 VQK-ATERIEELEWQKVRYKRAILQLDKSERKKNQNYFKEIDDLTKEEELTIHKRIIERE 644
Query: 270 -----------GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL 416
K + P+ +Q + E L + EK ER+ K+ L
Sbjct: 645 REKYKRKFERENEKRKFSKEDPIPDSQLL----EWLAKVDDLEKLYERESTTG--KIELR 698
Query: 417 KSMR-CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+S++ ++LK N+++ E+R+ + ++ KED TVALGTSK
Sbjct: 699 ESLQNLEKLKQNVEKLEKRITNCSLQLKDKEDNSTVALGTSK 740
[20][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 84.0 bits (206), Expect = 6e-15
Identities = 61/180 (33%), Positives = 84/180 (46%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L D E V KV Y NK VA +CNH RT+ H Q
Sbjct: 674 GLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVVVYQHANKEVAIICNHQRTISKSHTAQ 733
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E + LK LA+ KG PP++ A
Sbjct: 734 MTRLTEKIDEMKGVLNGLKTDLARAKKG----------KPPLK---------------DA 768
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K +++ + L+ + + ++ K+ D + KEDL+TVALGTSK
Sbjct: 769 DGKR---------------RNLTPEALERKIAQTNAKIEKMERDKDTKEDLKTVALGTSK 813
[21][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 83.6 bits (205), Expect = 8e-15
Identities = 73/214 (34%), Positives = 108/214 (50%), Gaps = 35/214 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GLSAKVFRT+NAS T+AE L+ P T+ DK+ FYN+ N+ VA LCNH R++ H Q
Sbjct: 557 GLSAKVFRTYNASYTMAEELKKMPKNLTLADKILFYNRANRTVAILCNHQRSVTKNHDVQ 616
Query: 180 MQK-------LETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVE--VTQYMPVK 332
M++ L+ +R + L+ LAK + G S V+ T Y K
Sbjct: 617 MERFAERIKALQYQRMRLRKMMLNLEPKLAKSKPELLAKEEGITDSWIVKHHETLYELEK 676
Query: 333 PEIL---------------ESMTADEKAQERKRAADLPKVPL---LKSMRCDQLKSNLKR 458
+I +S+ + + + R +AAD K L LKS + D +S++++
Sbjct: 677 EKIKKKFDRENEKLAAEDPKSVLPESELEVRLKAADELKKALDAELKSKKVDPGRSSMEQ 736
Query: 459 AEERLAKLT-------SDMEMKEDLQTVALGTSK 539
E+RL KL + M K++ +T ALGTSK
Sbjct: 737 LEKRLNKLNERINVMRTQMIDKDENKTTALGTSK 770
[22][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 83.2 bits (204), Expect = 1e-14
Identities = 58/180 (32%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL L + + TV +K+A Y + NK VA +CNH R++ H+ Q
Sbjct: 390 GLTAKVFRTYNASITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNHQRSVSKSHESQ 449
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M ++ + E + ++ELK L NK KG G S KP+
Sbjct: 450 MTRMNEKIDELKSQMEELKADL---NKAKKGKPLGYDSEG----------KPK------- 489
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+++ + ++ + E ++ K+ D +KEDL+TVALGTSK
Sbjct: 490 -------------------RNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSK 530
[23][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 82.8 bits (203), Expect = 1e-14
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRTFNAS+TL + L D + +K+ Y NK VA +CNH R++ H Q
Sbjct: 703 GLTAKVFRTFNASITLDDKLNKDTKDGDAAEKIVVYQHANKQVAIICNHQRSVSKSHSAQ 762
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M KL + E +KELK L + KG K+ S + PE+LE
Sbjct: 763 MTKLNEKIDELQDVLKELKVDLDRARKGKSPTKSSDGKSK-------RSLTPEVLE---- 811
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ + ++ K+ DM+ K DL+TVALGTSK
Sbjct: 812 ----------------------------KKISQTNAKIEKMQRDMKTKVDLKTVALGTSK 843
[24][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 82.8 bits (203), Expect = 1e-14
Identities = 62/180 (34%), Positives = 82/180 (45%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H Q
Sbjct: 742 GLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQ 801
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E ++ELK L++ KG AK GA P + PE LE A
Sbjct: 802 MSRLNEKIDELKTALEELKTDLSRAKKGKPPAK-GADGEPK------RNLNPESLERKIA 854
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
A ++ K+ D + KEDL+ VAL TSK
Sbjct: 855 QTNA--------------------------------KIEKMERDKKTKEDLKAVALSTSK 882
[25][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 82.4 bits (202), Expect = 2e-14
Identities = 60/180 (33%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NASVTL + L G + +KVA YN NK VA +CNH R++ H Q
Sbjct: 693 GLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQ 752
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
+ KL + E A ++E K LA+ KG PP++ A
Sbjct: 753 ISKLNEKIDELKALLEEFKVDLARAKKG----------KPPLK---------------GA 787
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D KA+ +++ + L+ + + ++ + +E KE+L+TVALGTSK
Sbjct: 788 DGKAK--------------RNLAPEALQKKIDQTNVKIENIEKQIETKEELKTVALGTSK 833
[26][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 81.6 bits (200), Expect = 3e-14
Identities = 60/180 (33%), Positives = 86/180 (47%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL E L + G V +K+ Y NK VA +CNH RT+ H Q
Sbjct: 710 GLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQ 769
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E + L+ LA+ KG PP+E A
Sbjct: 770 MTRLNGKIDELKGILDGLQTDLARAKKG----------KPPLE---------------DA 804
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K PK +++ + L+ + + ++ K+ D E KE L+T+ALGTSK
Sbjct: 805 DGK----------PK----RNLTPEALERKIGQTNAKIEKMERDKETKEGLKTIALGTSK 850
[27][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 80.9 bits (198), Expect = 5e-14
Identities = 60/180 (33%), Positives = 81/180 (45%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L + G V +KV Y + NK VA +CNH RT+ H Q
Sbjct: 742 GLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSAQ 801
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M +L + E ++ELK L++ K GK G P + PE LE A
Sbjct: 802 MSRLNEKIDELKTALEELKTDLSRAKK-GKPPSKGDDGEPK------RNLNPEALERKIA 854
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
A ++ K+ D + KEDL+ VAL TSK
Sbjct: 855 QTNA--------------------------------KIEKMERDKKTKEDLKAVALSTSK 882
[28][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 80.9 bits (198), Expect = 5e-14
Identities = 70/217 (32%), Positives = 103/217 (47%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T A L+ E TV +KV YN N+ VA LCNH RT+ +GH Q
Sbjct: 600 GLTAKVFRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQ 659
Query: 180 MQKLETR---------RAEAV-------------------------AWVKELKRGLAKWN 257
M+KL R R + + AW++E + L +
Sbjct: 660 MEKLGDRIKGLRYQKWRVKMMMLDIDPSQKKKKGSKYFELDEDLDQAWIQEHQAFLIEEQ 719
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERK--RAADLPKVPLL-KSMR 428
K K K + + +KP+ LE A K E+K + KV + K
Sbjct: 720 K-QKITKKFEKDNEKLAADGEKEMKPKELEERLAVLKDMEKKFQKENKTGKVEVEGKGQT 778
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++N+ + E+R+ ++ E KE+ + VALGTSK
Sbjct: 779 VEKLENNVTKLEQRIENMSLQAEDKENNKEVALGTSK 815
[29][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 80.5 bits (197), Expect = 7e-14
Identities = 60/180 (33%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL L + + V +KV Y + NK VA +CNH RT+ H Q
Sbjct: 727 GLTAKVFRTYNASITLDLMLSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQ 786
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL + E +KEL L + KG P+ M +
Sbjct: 787 VEKLAVKIEELREQIKELNIDLDRAKKG----------RTPL---------------MGS 821
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K RKR ++ + L+ + + + ++ K+ DM+ KED++TVALGTSK
Sbjct: 822 DGK---RKR-----------NLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSK 867
[30][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 80.5 bits (197), Expect = 7e-14
Identities = 60/180 (33%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL L + + V +KV Y + NK VA +CNH RT+ H Q
Sbjct: 42 GLTAKVFRTYNASITLDLMLSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQ 101
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
++KL + E +KEL L + KG P+ M +
Sbjct: 102 VEKLAVKIEELREQIKELNIDLDRAKKG----------RTPL---------------MGS 136
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D K RKR ++ + L+ + + + ++ K+ DM+ KED++TVALGTSK
Sbjct: 137 DGK---RKR-----------NLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSK 182
[31][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 80.1 bits (196), Expect = 9e-14
Identities = 57/180 (31%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL L + + TV +K+A Y + NK VA +CN R++ H+ Q
Sbjct: 720 GLTAKVFRTYNASITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNQQRSVSKSHESQ 779
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M ++ + E + ++ELK L NK KG G S KP+
Sbjct: 780 MTRMNEKIDELKSQMEELKADL---NKAKKGKPLGYDSEG----------KPK------- 819
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+++ + ++ + E ++ K+ D +KEDL+TVALGTSK
Sbjct: 820 -------------------RNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSK 860
[32][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 79.3 bits (194), Expect = 2e-13
Identities = 60/181 (33%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GLSAKVFRTFNAS+TL + LQ +P + V K+ YN+ N+ VA LCNH RT P +
Sbjct: 320 GLSAKVFRTFNASLTLQDQLQKLTNPEDNVNAKILSYNRANRAVAILCNHQRTAPKTFEK 379
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ + ++ VKE K+ L K +K+
Sbjct: 380 SMSNLQLKISDKKKTVKEAKKELKALRVKAKESKS------------------------E 415
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
++ KA E+K K+ ++R EE+L KL KE+ + +ALGTS
Sbjct: 416 SNNKAVEKK-------------------KAQVQRLEEQLFKLEVTATDKEENKEIALGTS 456
Query: 537 K 539
K
Sbjct: 457 K 457
[33][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 79.0 bits (193), Expect = 2e-13
Identities = 61/181 (33%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+
Sbjct: 566 GLTAKVFRTFNASWTLQQQLEKLTDPDVSVAEKILQYNRANRAVAILCNHQRAIPKTHEK 625
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ + A VKE K QY K ++ + +
Sbjct: 626 SMGNLKEKIQTKRAAVKEAKE-------------------------QYKQAKRDVKDG-S 659
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
K Q KR K L+R +E+L KL KE+ +T+ALGTS
Sbjct: 660 VHSKTQLEKR------------------KKALERLKEQLTKLEVQETDKEENKTIALGTS 701
Query: 537 K 539
K
Sbjct: 702 K 702
[34][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 79.0 bits (193), Expect = 2e-13
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH RT+ GH
Sbjct: 497 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKMLKYNAANRTVAILCNHQRTVTKGHAAS 556
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKWN-KGGKGAKAGAASSPPVEVTQYMPVKPEILE-- 347
+QK T R E + W K LKR + + + K K A + Q + ++E
Sbjct: 557 VQK-ATERIEELEWQKIRLKRAILQLDEKQAKKDPKFFAEVTDLVKEQEAAIHKRLIEKE 615
Query: 348 ------SMTADEKAQERKRAADLPKVPL--------------------------LKSMRC 431
+ + + ++ ++ +LP+ L S
Sbjct: 616 REKYVKKFSRENEKRKFEKQEELPESQLKEWMARVDELEKQYNEELESGKVQLKTNSESA 675
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++LK +++ ++R+ T ++ KED VALGTSK
Sbjct: 676 EKLKMQIEKLDQRIETATIQLKDKEDNSQVALGTSK 711
[35][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 79.0 bits (193), Expect = 2e-13
Identities = 69/217 (31%), Positives = 102/217 (47%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T A L+ E TV +KV YN N+ VA LCNH RT+ +GH Q
Sbjct: 604 GLTAKVFRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQ 663
Query: 180 MQKLETR---------RAEAV-------------------------AWVKELKRGLAKWN 257
M+KL R R + + AW++E + L +
Sbjct: 664 MEKLGDRIKGLRYQKWRVKMMMLDLDPSQKKKKGAKYFELDDDLDQAWIQEHQAFLVEEQ 723
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERK--RAADLPKVPLL-KSMR 428
K K K + + +KP+ L+ A K E+K + KV K
Sbjct: 724 K-QKITKKFEKENEKLAAEGEKEMKPKELDERLAVLKDMEKKFQKENKTGKVEAEGKGQT 782
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++N+ + E+R+ ++ E KE+ + VALGTSK
Sbjct: 783 IEKLENNVAKLEQRIETMSLQAEDKENNKEVALGTSK 819
[36][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 77.8 bits (190), Expect = 5e-13
Identities = 60/181 (33%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L PGE + +K+ YN+ N+ VA LCNH R P +
Sbjct: 566 GLTAKVFRTYNASITLQQQLNELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEK 625
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E K+ L+ K K AKA A +
Sbjct: 626 SMQNLQTK-------IDEKKKQLSAAKKEHKAAKADAKA--------------------L 658
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+ K+A + K ++R E+L KL +E+ + +ALGTS
Sbjct: 659 HDEKS---KKAVETK-------------KKAVQRISEQLMKLEVQATDREENKQIALGTS 702
Query: 537 K 539
K
Sbjct: 703 K 703
[37][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 76.6 bits (187), Expect = 1e-12
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L + ++VT+K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 78 GLTAKVFRTYNASHTLQEQLDKLTNAEDSVTEKILSYNRANRAVAILCNHQRSVPKGHQK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + ++E++R + + AK G+ + E +
Sbjct: 138 SMEKLKEKIDQKREQIEEMQRQV---KDAARDAKHGS-----------------VKEKLV 177
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+K K +L R +E+L KL +++ +++ALGTS
Sbjct: 178 HDKK------------------------KKSLDRLKEQLKKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[38][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 76.6 bits (187), Expect = 1e-12
Identities = 62/216 (28%), Positives = 98/216 (45%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E T +KV +N N+ VA LCNH RT+ H
Sbjct: 591 GLTAKVFRTYNASKTMQDQLDLIPNEGTAAEKVVKFNAANRTVAILCNHQRTVSKNHGNS 650
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKG------AKAGAASSPPVEVTQYMPV---- 329
+QK+ + E + LK+ + K K + S+ +E ++ +
Sbjct: 651 VQKINDKLRELIWQKIRLKKMILKLEPKLKKKDPKYFEELEDLSNEEIEHIHHLVIERHR 710
Query: 330 ------------------KP--------EILESMTADEKAQERKRAADLPKVPLLKSMRC 431
KP E L+ +T EK +++ P++P K
Sbjct: 711 QQVQKKFERDNEKLKLEKKPLLKKKDIKEKLDKITELEKEYKKELKTGKPEIP--KGATV 768
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++LK+ ++ E R+ T ++ KED V+LGTSK
Sbjct: 769 EKLKTQVENMENRIVSTTLQLKDKEDNSEVSLGTSK 804
[39][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 76.3 bits (186), Expect = 1e-12
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L + ++VT+K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 78 GLTAKVFRTYNASSTLQEQLDLLTNEDDSVTEKILSYNRANRAVAILCNHQRSVPKGHQK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ K +A+ K K A A ++ VK +++
Sbjct: 138 SMEKLKEK-------IEQKKEHIAEMQKQVKDAAKDA---------KHGSVKEKVVH--- 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +++L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKALERLKDQLKKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[40][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 76.3 bits (186), Expect = 1e-12
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L + +T+++K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 78 GLTAKVFRTYNASSTLQEQLDLLTNEDDTLSEKILSYNRANRAVAILCNHQRSVPKGHQK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + +++E+++ + K AK G+ VK +++
Sbjct: 138 SMEKLKEKIEQKREFIQEMQKXV---KDAAKDAKHGS-------------VKEKVVH--- 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R ++L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKALERLRDQLMKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[41][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 76.3 bits (186), Expect = 1e-12
Identities = 68/216 (31%), Positives = 99/216 (45%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GLSAKVFRT+NAS T+ + L P E +V +KV YN N+ VA LCNH RT P H
Sbjct: 504 GLSAKVFRTYNASKTMQDQLDLIPNEGSVGEKVVKYNAANREVAILCNHQRTKPKSHDMG 563
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAK---------AGAASSPPVE-------- 308
+Q++ E LKR + + +K K K ++
Sbjct: 564 VQRISDNIRELFWQKLRLKRMILELDKSLKKTKPYYFEELDDLSVEEEQAIQDRVIAKER 623
Query: 309 --------------VTQYMPVKPEIL---ESMTADEKAQERKRAADLPKVPLLKS--MRC 431
T+ P+ PE + + DE A E K+ K P +KS +
Sbjct: 624 EKATKKFTRDNEKLKTEDSPLLPEAMLEEKLKKIDELAAEYKKELKTRK-PEIKSVTVTV 682
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L+S +++ E+R+ T ++ KED VALGTSK
Sbjct: 683 EKLESQVEKLEQRIRNATLLLQDKEDNSQVALGTSK 718
[42][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 75.9 bits (185), Expect = 2e-12
Identities = 66/198 (33%), Positives = 97/198 (48%), Gaps = 20/198 (10%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLAECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
LSAKVFRT+NAS+TL + L P T +KV FYN+ N+ VA LCNH R+L H
Sbjct: 778 LSAKVFRTYNASLTLEKELAKMPESLIKATADEKVLFYNRCNREVAILCNHQRSLSKTHT 837
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL--- 344
M K++ + AE + KE + + K GKG K + S E T +
Sbjct: 838 ETMGKIDEKIAE---FKKEKLQQQIAYLK-GKGKKPVLSDSESDEDTPKKATPKKATPKK 893
Query: 345 ESMTADEKAQERKR--------AADLPKVPLLKSMRC-----DQLKSNLKRAEERLAKLT 485
E+ ++DE +KR A D + P K R ++ K+ ++R + + K
Sbjct: 894 ETKSSDEATPNKKRKKDDDEEEADDFKETPKKKVKRALPDSVEKCKAAIERVDTSINKWN 953
Query: 486 SDMEMKEDLQTVALGTSK 539
K++L++VAL TSK
Sbjct: 954 IKKTEKDELKSVALTTSK 971
[43][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 75.9 bits (185), Expect = 2e-12
Identities = 54/181 (29%), Positives = 90/181 (49%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL + L + +T+++K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 112 GLTAKVFRTFNASYTLQQQLDELTNADDTLSEKILSYNRANRAVAILCNHQRSVPKGHQK 171
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + + + + K K A+ A Q+ VK +++
Sbjct: 172 TMEKLKEK-------IDQKREQITEMQKQVKDAQRDA---------QHGSVKEKVV---- 211
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +++L KL K++ +++ALGTS
Sbjct: 212 ------------------------LDKKKKGLERLKDQLVKLEVQETDKDENKSIALGTS 247
Query: 537 K 539
K
Sbjct: 248 K 248
[44][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 75.9 bits (185), Expect = 2e-12
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 33/212 (15%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG-------------DPGET--------------VTDKVA 101
GL+AKVFRT+NAS+TL L+ PG++ V + ++
Sbjct: 479 GLTAKVFRTYNASITLCRQLRRLKVRKSLDSSLMLQPGKSDDDLDKPVLVDVTDVNELIS 538
Query: 102 FYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKA 281
FYN+ N+ VA LCNH R++P H+ M K++ A+A
Sbjct: 539 FYNEANRRVAILCNHQRSIPKQHESSMSKMQ--------------------------AQA 572
Query: 282 GAASSPPVEVTQYM------PVKPEILESMTADEKAQERKRAADLPKVPLLKSMRCDQLK 443
S E+ YM KP ES T D K RK A + M+ + +
Sbjct: 573 ELISEEIAELQAYMKYLESNQTKPFTFESRTVDAKGNPRKAAT-------RQGMKLEACQ 625
Query: 444 SNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
L+ A +R M +K+D +TVALGTSK
Sbjct: 626 KKLETAMKRSKVHAIKMRIKDDNKTVALGTSK 657
[45][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 75.1 bits (183), Expect = 3e-12
Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGD---PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GL+AKVFRT+NAS TL + L G +V KV FY+ NK VA LCNH +T+ +
Sbjct: 400 GLTAKVFRTYNASFTLQQQLDLGGKLDGHSVQQKVDFYDNANKQVAILCNHQKTISKQFE 459
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
+K+ T+ +++EL++ K N P E
Sbjct: 460 LTKKKINTKLECMKTYIQELEQHYKKKN-------------------------PNEYEEE 494
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
E+ ++K + + K P + D++K +++ +E+ K +E KE+ + +ALGT
Sbjct: 495 VQLEEGSQKKNSIFIKKFP----GQHDKIKQTIQKTQEKYQKELKGLEKKEENKEIALGT 550
Query: 534 SK 539
SK
Sbjct: 551 SK 552
[46][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 75.1 bits (183), Expect = 3e-12
Identities = 65/225 (28%), Positives = 99/225 (44%), Gaps = 46/225 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T++ LQ P E T+ +KV YN N+ VA LCNH RT+ +GH+
Sbjct: 629 GLTAKVFRTYNASFTMSRLLQELPVEKATIAEKVKLYNDCNRKVAILCNHKRTVGAGHQA 688
Query: 177 QMQKLETR---------RAEAV-------------------------AWVKELKRGL--- 245
QM+KL R R + + W++E L
Sbjct: 689 QMEKLGDRIKGLKYQQWRTKMMILDVDPKQKKKLGADFFKLDEELDNEWIEEHLNFLYEE 748
Query: 246 ------AKWNKGGKGAKA-GAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPK 404
K+ K + A G+ P E+ + + E+L + + K ++ + P
Sbjct: 749 QRTKITKKFEKDNEKLVAEGSKKLPEKELKERLKAASELLTKLKKEHKTKKVEAEGRSPT 808
Query: 405 VPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
V ++L K+ EER L + ++ + VALGTSK
Sbjct: 809 V--------EKLLEGAKKIEERAKNLELQAQDRDGNKEVALGTSK 845
[47][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 74.7 bits (182), Expect = 4e-12
Identities = 56/181 (30%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + ++V +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 755 GLTAKVFRTYNASWTLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEK 814
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +K+ +R + K AK G+ E T Y
Sbjct: 815 SMEKLKEKIDAKKEAIKDAERQV---KDAAKDAKHGSVK----EKTVY------------ 855
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ +T+ALGTS
Sbjct: 856 -------------------------DKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTS 890
Query: 537 K 539
K
Sbjct: 891 K 891
[48][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 74.7 bits (182), Expect = 4e-12
Identities = 57/184 (30%), Positives = 87/184 (47%), Gaps = 5/184 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L+ DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 838 GLTAKVFRTYNASWTLQQQLEELTDPNSTVAEKILSYNRANRAVAILCNHQRSVPKSHEK 897
Query: 177 QMQKLETR---RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 347
M+ L+ + + EA+A +++ + + K G VK ++L
Sbjct: 898 SMENLKAKIDAKREAIAEAEQIVKDAKRDAKHGS-------------------VKEKVL- 937
Query: 348 SMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVAL 527
E+K K L R +E+L KL +E+ + +AL
Sbjct: 938 --------YEKK-------------------KKQLDRLKEQLMKLEVQATDREENKEIAL 970
Query: 528 GTSK 539
GTSK
Sbjct: 971 GTSK 974
[49][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 74.7 bits (182), Expect = 4e-12
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + P E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 496 GLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKVVRFNAANRTVAILCNHQRTVSKTHGHS 555
Query: 180 MQKLETRRAEAVAWVK--------ELKRGLAKWNKGG--------------------KGA 275
+Q++ R E + W K EL+ GL + + + A
Sbjct: 556 VQRIHDRIKE-MMWQKIRTKKMILELEPGLRRKDPKYFEELEDLSKEDEQHVHHLLLERA 614
Query: 276 KAGAASSPPVEVTQYMPVKPEILESMTADE-----KAQERKRAADLPK-VPLLKS-MRCD 434
+ A E + E+L S DE K QE+ A +L P++KS +
Sbjct: 615 REQAQRKFERENQKLKAEGKELLSSSVLDEKMEKIKEQEKDLAEELKTGKPVMKSTTTVE 674
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+LK+ +++ + R+ T ++ KED V+LGTSK
Sbjct: 675 KLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSK 709
[50][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 74.7 bits (182), Expect = 4e-12
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + P E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 496 GLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKVVRFNAANRTVAILCNHQRTVSKTHGHS 555
Query: 180 MQKLETRRAEAVAWVK--------ELKRGLAKWNKGG--------------------KGA 275
+Q++ R E + W K EL+ GL + + + A
Sbjct: 556 VQRIHDRIKE-MMWQKIRTKKMILELEPGLRRKDPKYFEELEDLSKEDEQHVHHLLLERA 614
Query: 276 KAGAASSPPVEVTQYMPVKPEILESMTADE-----KAQERKRAADLPK-VPLLKS-MRCD 434
+ A E + E+L S DE K QE+ A +L P++KS +
Sbjct: 615 REQAQRKFERENQKLKAEGKELLSSSVLDEKMEKIKEQEKDLAEELKTGKPVMKSTTTVE 674
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+LK+ +++ + R+ T ++ KED V+LGTSK
Sbjct: 675 KLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSK 709
[51][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 74.3 bits (181), Expect = 5e-12
Identities = 57/181 (31%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L+ +P +TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 786 GLTAKVFRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEK 845
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+ L+ + E KR Q +K E+ +
Sbjct: 846 SMENLKAK--------IEAKR------------------------EQINEIKKEVKNAKR 873
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ E K+ K L R +E+L KL KE+ +T+ALGTS
Sbjct: 874 NGDSGTEAKK------------------KKQLDRLKEQLLKLEVQETDKEENKTIALGTS 915
Query: 537 K 539
K
Sbjct: 916 K 916
[52][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 74.3 bits (181), Expect = 5e-12
Identities = 57/182 (31%), Positives = 90/182 (49%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP +V +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 862 GLTAKVFRTYNASKTLQNQLDLLTDPNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQK 921
Query: 177 QMQKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M+ L+ + RA+ A L ++++ K AK G+ + E +
Sbjct: 922 SMENLKEKIRAKRDA----LDECESEYHDLRKAAKRGS-----------------VKEKL 960
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
AD+K ++ L+R +++L KL +++ +T+ALGT
Sbjct: 961 NADKKGKQ------------------------LERLKDQLKKLELQETDRDENKTIALGT 996
Query: 534 SK 539
SK
Sbjct: 997 SK 998
[53][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 74.3 bits (181), Expect = 5e-12
Identities = 61/181 (33%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + L+ P G TV +K+ Y + N+ VA LCNH R P H Q
Sbjct: 2230 GLTAKVFRTYNASITLQDQLKSTPAGGTVEEKLLAYQRANRAVAILCNHQRAAPKTHDEQ 2289
Query: 180 MQKLETRRAEAVAWV-KELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M++L+ EA+ + KEL + + K K +A
Sbjct: 2290 MERLD----EALVKIQKELDSTIKERKKLKKDLRA------------------------- 2320
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ +D+ K L R D LK + R EERL K KE+ + +AL TS
Sbjct: 2321 ---------QGSDVSKTDL---NRLDVLKRKVDRLEERLHKKQIAKVDKEENKCIALSTS 2368
Query: 537 K 539
K
Sbjct: 2369 K 2369
[54][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 74.3 bits (181), Expect = 5e-12
Identities = 67/228 (29%), Positives = 103/228 (45%), Gaps = 49/228 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSG 167
GL+AKVFRT+NAS T++E L+G DP +V +KV YN N+ VA LCNH RT+ +G
Sbjct: 653 GLTAKVFRTYNASFTMSELLKGLSKDPRSRGSVAEKVKLYNDCNREVAILCNHKRTVGAG 712
Query: 168 HKGQMQKLETR-----------------------RAEAVA-----------WVKELKRGL 245
H+ QMQKL R + + A W+KE ++ L
Sbjct: 713 HEQQMQKLGDRIKGLRYQQWRTKKMILDIDPTQKKKKGAAWFELDEDLDEEWIKEHQQFL 772
Query: 246 ---------AKWNKGGKGAKAG-AASSPPVEVTQYMPVKPEILESMTADEKAQERKRAAD 395
K+ K + KA P E+ + + V E+ + K ++ +
Sbjct: 773 IEEQRTKITKKFEKDNEKLKANKERPMPEKELKERLQVVKELEAKFKKENKTKKVEAEGR 832
Query: 396 LPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
P V D+ +++ +ER+ L + E ++ + VALGTSK
Sbjct: 833 GPTV--------DKFIKAIEKLDERVKVLETQAEDRDGNKEVALGTSK 872
[55][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 73.9 bits (180), Expect = 7e-12
Identities = 58/181 (32%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +P + + K+ YN+ N+ VA LCNH R++P
Sbjct: 480 GLTAKVFRTYNASITLQEQLKALTNPEDNIAGKLLSYNRANRAVAILCNHQRSIPKTFAK 539
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+ + A VE Q K E T
Sbjct: 540 SMQVLQEKI---------------------------DAKKKQVEEAQEEVKKAEDEFKDT 572
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D KA+ + ++ K LKR EE+LAK+ KE+ + +ALGTS
Sbjct: 573 KDAKAE----------------LNVEKKKKLLKRLEEQLAKMNIQATDKEENKQIALGTS 616
Query: 537 K 539
K
Sbjct: 617 K 617
[56][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 73.9 bits (180), Expect = 7e-12
Identities = 53/181 (29%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH
Sbjct: 112 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKGHAK 171
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + E++R
Sbjct: 172 SMEKLKEKIEQKKDTISEMER--------------------------------------- 192
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ Q+ +RAA V + + D+ K L++ +++L KL K++ +++ALGTS
Sbjct: 193 ---QVQDAQRAAKRGSVK--EKVVYDKKKKALEKLKDQLVKLEVQETDKDENKSIALGTS 247
Query: 537 K 539
K
Sbjct: 248 K 248
[57][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 73.6 bits (179), Expect = 9e-12
Identities = 57/182 (31%), Positives = 90/182 (49%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 873 GLTAKVFRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQK 932
Query: 177 QMQKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M+ L+ + RA+ A + ++++ K AK G+ + E +
Sbjct: 933 SMENLKEKIRAKRDA----IDDCESEYHDLKKAAKRGS-----------------VKEKV 971
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
AD+K ++ L+R +++L KL +++ +T+ALGT
Sbjct: 972 NADKKGKQ------------------------LERLKDQLKKLELQETDRDENKTIALGT 1007
Query: 534 SK 539
SK
Sbjct: 1008 SK 1009
[58][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 73.6 bits (179), Expect = 9e-12
Identities = 57/182 (31%), Positives = 90/182 (49%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 861 GLTAKVFRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQK 920
Query: 177 QMQKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M+ L+ + RA+ A + ++++ K AK G+ + E +
Sbjct: 921 SMENLKEKIRAKRDA----IDDCESEYHDLKKAAKRGS-----------------VKEKV 959
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
AD+K ++ L+R +++L KL +++ +T+ALGT
Sbjct: 960 NADKKGKQ------------------------LERLKDQLKKLELQETDRDENKTIALGT 995
Query: 534 SK 539
SK
Sbjct: 996 SK 997
[59][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 73.6 bits (179), Expect = 9e-12
Identities = 64/221 (28%), Positives = 100/221 (45%), Gaps = 42/221 (19%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L Q + T+ +KV YN N+ VA LCNH RT+ +GH Q
Sbjct: 645 GLTAKVFRTYNASYTMATLLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQ 704
Query: 180 MQKLETR--RAEAVAW-VKELKRGLAKWNKGGKGA------------------------- 275
M+KL R W +K++ L K KGA
Sbjct: 705 MEKLGERIKGLRYQKWRIKQMMLDLDPKIKKKKGAEFFELDPDLDEEWIKQHQAFLVEEQ 764
Query: 276 -------------KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL 416
K A ++V + + + E+ E + A K + + + +
Sbjct: 765 RQKIQKKFDKDNEKLRAEGEKEMKVKE-LEKRLEVAEELAAKFKKENKTKKVEAEG---- 819
Query: 417 KSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K ++ ++NL + ++R+ ++ + KED + VALGTSK
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSK 860
[60][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 73.6 bits (179), Expect = 9e-12
Identities = 64/221 (28%), Positives = 100/221 (45%), Gaps = 42/221 (19%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L Q + T+ +KV YN N+ VA LCNH RT+ +GH Q
Sbjct: 645 GLTAKVFRTYNASYTMATLLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQ 704
Query: 180 MQKLETR--RAEAVAW-VKELKRGLAKWNKGGKGA------------------------- 275
M+KL R W +K++ L K KGA
Sbjct: 705 MEKLGERIKGLRYQKWRIKQMMLDLDPKIKKKKGAEFFELDPDLDEEWIKQHQAFLVEEQ 764
Query: 276 -------------KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL 416
K A ++V + + + E+ E + A K + + + +
Sbjct: 765 RQKIQKKFDKDNEKLRAEGEKEMKVKE-LEKRLEVAEELAAKFKKENKTKKVEAEG---- 819
Query: 417 KSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K ++ ++NL + ++R+ ++ + KED + VALGTSK
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSK 860
[61][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 73.6 bits (179), Expect = 9e-12
Identities = 63/216 (29%), Positives = 97/216 (44%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ GH
Sbjct: 520 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKGHGSS 579
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKA---------GAASSPPVEVTQYMPVK 332
+QK+ + E + LKR + K ++ + T +
Sbjct: 580 VQKINDKLKELMWQKIRLKRMILVLEPKLKNKQSHYFCEIDDLAKEDEEHIHHTVIARQR 639
Query: 333 PEILESMTAD-------------EKAQERK----RAADL----------PKVPLLKSMRC 431
++L+ M D EK+ E K + DL K + K++
Sbjct: 640 EQVLKKMQRDNEKLKLEKQEILTEKSDEIKEKMAKIDDLEKEYKAELNGAKPEVKKNLTV 699
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L+ ++ E R+ T ++ KED V+LGTSK
Sbjct: 700 EKLQQQVEVIENRIVTTTLQLKDKEDNSEVSLGTSK 735
[62][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 73.2 bits (178), Expect = 1e-11
Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P +
Sbjct: 411 GLTAKVFRTYNASITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEK 470
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + K L K + E+ E+
Sbjct: 471 SMQNLQTK-------IDAKKEQLEK-------------------------AQQELEEAED 498
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ ++ K A ++ K K L+R +E+LAKL KE+ + +ALGTS
Sbjct: 499 EFKDKKDAKAAGNVQK-----------KKKLLERLKEQLAKLNVQATDKEENKQIALGTS 547
Query: 537 K 539
K
Sbjct: 548 K 548
[63][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 73.2 bits (178), Expect = 1e-11
Identities = 69/220 (31%), Positives = 99/220 (45%), Gaps = 41/220 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E +VT+K+ YN N+ VA LCNH RT+ H
Sbjct: 473 GLTAKVFRTYNASKTMQDQLDLIPNEGSVTEKMVRYNAANRAVAILCNHQRTVGRSHAQS 532
Query: 180 MQKLETRRAEAVAWVK-------------EL----------------------KRGLAKW 254
MQK T + E W K EL KR L +
Sbjct: 533 MQK-ATEKIEEYQWQKIRYKKAILQLDESELKANPKFFKEINDLTKEEQMSIHKRVLERE 591
Query: 255 NKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPK-----VPLLK 419
+ + A E + +P LES AD + ++ +L P L+
Sbjct: 592 REKYQKKFARENEKRKFEGEELLPESQ--LESWLADVEEMGKEYVEELETGLVTVKPTLQ 649
Query: 420 SMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
S+ ++LK+ + + E+R+ + M+ KED TVAL TSK
Sbjct: 650 SV--EKLKAQIDKLEQRIRTTSIQMKDKEDNSTVALSTSK 687
[64][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 73.2 bits (178), Expect = 1e-11
Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 46/225 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GLSAKVFRT NAS T++E L+ P + +++DKV YN+ N++VA LCNH RT+ H Q
Sbjct: 505 GLSAKVFRTHNASYTMSEQLKNTPKDASISDKVLAYNRANRMVAILCNHQRTISKTHSAQ 564
Query: 180 MQKLETR----------------------------RAEAVA-----WVKE---------- 230
M+++E + +EAV+ W+KE
Sbjct: 565 MERIEDKILALKYQKIRLRKAILTLDPKLEKSRPDLSEAVSDIDEDWIKEHQKVLIEKEY 624
Query: 231 --LKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPK 404
+KR K N+ K P + +++ E + M + K + K +
Sbjct: 625 DKIKRKFQKDNE--KLISQNETPMPESRLEKFL----EKINEMKEEFKIENEKGRVESKT 678
Query: 405 VPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ + + L +K+ ER+ ++ + M K +T ALGTSK
Sbjct: 679 ----RGITIETLDLQIKKINERIHQMKALMIDKAQNKTTALGTSK 719
[65][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 73.2 bits (178), Expect = 1e-11
Identities = 61/216 (28%), Positives = 100/216 (46%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+G T+ +K+ YN N+ VA LCNH RT+ + H Q
Sbjct: 645 GLTAKVFRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQ 704
Query: 180 MQKL-----------------------ETRRAEAVA-----------WVKELKRGLAKWN 257
M+KL + ++ + A W+KE + L +
Sbjct: 705 MEKLGDRIKGLKYQQWRLKQMMLDLDPKLKKKKGAAYFELDESLDQEWIKEHQAFLVEEQ 764
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA--DEKAQERKRAADLPKVPLLKSMRC 431
+ K + V + E+ E + A + +A+ +K VP K +
Sbjct: 765 RQKIKKKFEKDNEKRVAEGEKEMKAKELEERLEAANELEAKFKKENKSKKVVPEGKGVTV 824
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ L + +R+ ++ E KE+ + VALGTSK
Sbjct: 825 EKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSK 860
[66][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 72.8 bits (177), Expect = 1e-11
Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P +
Sbjct: 411 GLTAKVFRTYNASITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEK 470
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + K L K + E+ E+
Sbjct: 471 SMQNLQTK-------IDAKKEQLEK-------------------------AQQELEEAED 498
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ ++ K A++ K K L+R +E+LAKL KE+ + +ALGTS
Sbjct: 499 EFKDKKDAKAEANVQK-----------KKKLLERLKEQLAKLNVQATDKEENKQIALGTS 547
Query: 537 K 539
K
Sbjct: 548 K 548
[67][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 72.8 bits (177), Expect = 1e-11
Identities = 53/181 (29%), Positives = 88/181 (48%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 112 GLTAKVFRTYNASWTLQQQLDELTNDDDTVAEKILSYNRANRAVAILCNHQRSVPKGHQK 171
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + E++R + K A+ A + + E M
Sbjct: 172 TMEKLKEKIEQKREQINEMQRQV-------KDAQRDARNG-------------SVKEKMV 211
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+K K L++ +E++ +L K++ +++ALGTS
Sbjct: 212 FDKK------------------------KKALEKLKEQMIRLEVQETDKDENKSIALGTS 247
Query: 537 K 539
K
Sbjct: 248 K 248
[68][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 72.8 bits (177), Expect = 1e-11
Identities = 56/185 (30%), Positives = 89/185 (48%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + ++V++K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 60 GLTAKVFRTYNASFTLQQQLDQLTNADDSVSEKMLSYNRANRAVAVLCNHQRSVPKGHEK 119
Query: 177 QMQKLE----TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
M+KL+ T+R + K++K K AK G+ +
Sbjct: 120 SMEKLKEKIGTKRDQIAEMEKQVK-------DAQKDAKRGS-----------------VK 155
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E + D+K K +L+R E+L KL +++ +++A
Sbjct: 156 EKVVYDKK------------------------KKHLERLREQLVKLEVAETDRDENKSIA 191
Query: 525 LGTSK 539
LGTSK
Sbjct: 192 LGTSK 196
[69][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 72.4 bits (176), Expect = 2e-11
Identities = 60/181 (33%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L + + V K+ YN+ N+ VA LCNH R P +
Sbjct: 576 GLTAKVFRTYNASITLQQQLNELTNSEDNVPAKILSYNRANRAVAILCNHQRAPPKTFEK 635
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E KR L KGAKA A +
Sbjct: 636 SMQNLQTKIDAKKEQLVEAKREL-------KGAKADA--------------------KVR 668
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK ++ A K L+R EE+L KL +E+ + +ALGTS
Sbjct: 669 KDEKFKKAVEAK----------------KKALQRVEEQLMKLEVQATDREENKQIALGTS 712
Query: 537 K 539
K
Sbjct: 713 K 713
[70][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 72.4 bits (176), Expect = 2e-11
Identities = 54/181 (29%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L +TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTSADDTVAEKILSYNRANRAVAILCNHQRSVPKGHQK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + V + +R L + AK G+ + E +
Sbjct: 138 SMEKLKEKIEQKREQVADAQRQL---KDAQRDAKRGS-----------------VKERVV 177
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
AD+K K L R ++L +L +++ +++ALGTS
Sbjct: 178 ADKK------------------------KKQLDRLRDQLVRLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[71][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 72.4 bits (176), Expect = 2e-11
Identities = 63/215 (29%), Positives = 99/215 (46%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + P E TV +KV YN N+ VA LCNH RT+ H+
Sbjct: 506 GLTAKVFRTYNASKTMQDQMDLIPNEGTVAEKVMKYNAANRTVAILCNHQRTVSKAHQNS 565
Query: 180 MQKLETRRAEAVAWVK-ELKRGL--------AKWNKGGKGAKAGAASSPPVEVTQYMP-- 326
+ K++ + E + W K LK+ + AK K + + + + VTQ +
Sbjct: 566 VGKIQEKIKE-MEWQKIRLKKMILVLDSSQKAKNPKYFEELEDMTSEDQLMVVTQMIERQ 624
Query: 327 -----------------VKPEILESMTADEK-------AQERKRAADLPKVPLLKSMRCD 434
K E+L EK +E + + +V + K +
Sbjct: 625 REQAKRKWTRDNEKRAMEKQELLTEEDLQEKLSKIKASEEEYRHEIESGEVEVTKGASVE 684
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+LK +++ E R+ ++ KED V+LGTSK
Sbjct: 685 KLKVQIEKIENRILNTNFQLKDKEDNSEVSLGTSK 719
[72][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 72.0 bits (175), Expect = 3e-11
Identities = 55/180 (30%), Positives = 77/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+ KVFRT+NAS+TL L+ +T K A Y+ NK VA LCNH + + H Q
Sbjct: 316 GLTIKVFRTYNASITLDRLLKDTKKNDTTLQKKATYDAANKEVAILCNHQKGVSKAHDAQ 375
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M+KL ++ + V E+K+
Sbjct: 376 MEKLAEKKKDLAKQVAEMKK--------------------------------------KT 397
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D+K Q++K AA +ER +KL M MKE+L+TV+LGTSK
Sbjct: 398 DDKNQKKKLAA----------------------LKERQSKLAIQMNMKEELKTVSLGTSK 435
[73][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 72.0 bits (175), Expect = 3e-11
Identities = 60/216 (27%), Positives = 100/216 (46%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+G T+ +K+ YN N+ VA LCNH RT+ + H Q
Sbjct: 640 GLTAKVFRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQ 699
Query: 180 MQKL-----------------------ETRRAEAVA-----------WVKELKRGLAKWN 257
M+KL + ++ + A W++E + L +
Sbjct: 700 MEKLGDRIKGLKYQQWRLKQMMLDLDPKLKKKKGAAYFELDESLDQEWIREHQAFLVEEQ 759
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA--DEKAQERKRAADLPKVPLLKSMRC 431
+ K + V + E+ E + A + +A+ +K VP K +
Sbjct: 760 RQKIKKKFEKDNEKRVAEGEKEMKAKELEERLEAANELEAKFKKENKSKKVVPEGKGVTV 819
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ L + +R+ ++ E KE+ + VALGTSK
Sbjct: 820 EKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSK 855
[74][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 71.6 bits (174), Expect = 3e-11
Identities = 61/224 (27%), Positives = 99/224 (44%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+AE L+ + +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 612 GLTAKVFRTYNASHTMAELLKDMKATGNIAEKVKAYNDANRRVAILCNHKRTVGASHANQ 671
Query: 180 MQKLETR-----------RAEAV-----------------------AWVKELKRGLA--- 248
M+K+ R + + + W+KE + L
Sbjct: 672 MEKMSERIKGLRYQRWRLKQQMLDLDPNLKKKKGAKFFELDEDIDKEWIKEHQAFLVEEQ 731
Query: 249 ------KWNKGG-KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
K+ K K A G E+ + + V E+ + + K + + P V
Sbjct: 732 RQKIRKKFEKDNEKLAAEGEKEMKASELEERLQVATELEKKYNRENKTGKVEAEGKAPTV 791
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+++++N+++ E+R+ + + KED + VALGTSK
Sbjct: 792 --------EKIEANIQKLEQRIETMELQAQDKEDNKEVALGTSK 827
[75][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 71.2 bits (173), Expect = 4e-11
Identities = 58/188 (30%), Positives = 80/188 (42%), Gaps = 9/188 (4%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--------DPGETVTDKVAFYNKQNKVVAELCNHVRTL 158
GLS KVFRT+NAS+ L L +TV K Y+ NK VA LCNH R++
Sbjct: 395 GLSVKVFRTYNASIVLDRLLSEWEATKKGHSTAQTVDQKKVDYDIANKEVAILCNHQRSV 454
Query: 159 PSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKG-GKGAKAGAASSPPVEVTQYMPVKP 335
P H QM+K++ + A + EL+ L KG + KA +P +
Sbjct: 455 PKTHTNQMEKIQEKLAGMNKELAELEDELRAAQKGKAENKKANKCGAPTI---------- 504
Query: 336 EILESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQ 515
LP L S + + ++ +AK+ KEDL+
Sbjct: 505 --------------------LPWA----------LNSKIDKKKQAIAKVELQARSKEDLK 534
Query: 516 TVALGTSK 539
TVALGTSK
Sbjct: 535 TVALGTSK 542
[76][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 71.2 bits (173), Expect = 4e-11
Identities = 63/217 (29%), Positives = 105/217 (48%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH R++ GH
Sbjct: 485 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKLLKYNAANRAVAILCNHQRSVTKGHAQS 544
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKW--NKGGKGAKAGAASSPPVEVTQY---------- 320
++K+ ++ E + W K LK+G+ + ++ K K + +V Q
Sbjct: 545 VEKM-NQKIEELLWQKIRLKKGILQLEPSRAQKNKKYFKEINDMTKVEQATIHKRIVDRE 603
Query: 321 ----------------------MPVKPEILESM-TADEKAQERKRAADLPKVPLLKSMR- 428
+P K E+ E + D+ ++ K KV L +M+
Sbjct: 604 RERLKKKFERDNEKLVAEKKDPLP-KTELKEWLKKVDDLEKQYKTELKTGKVELKATMQS 662
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L+ +++ EER+ + ++ KE+ V+LGTSK
Sbjct: 663 VEKLEKQVEKLEERIKTSSIQLKDKEENSQVSLGTSK 699
[77][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 214 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 273
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 274 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 309
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 310 ----KSRSVLEKKRRL-------------------LEKLQEQLAQLSVQATDKEENKQVA 346
Query: 525 LGTSK 539
LGTSK
Sbjct: 347 LGTSK 351
[78][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 70.9 bits (172), Expect = 6e-11
Identities = 58/184 (31%), Positives = 79/184 (42%), Gaps = 5/184 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL L+ DP TV +K+ YN+ N+ VA LCNH R +P H+
Sbjct: 789 GLTAKVFRTFNASFTLQNQLRELTDPDMTVPEKLLAYNRANRAVAILCNHQRAVPKTHEK 848
Query: 177 QMQKLETR---RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 347
M L+ + + EAV + + L K N K AK
Sbjct: 849 SMSNLKEKIRAKQEAVETCERELKDLKKSNVRDKVAK----------------------- 885
Query: 348 SMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVAL 527
D+ + L+R E+L KL K++ +T+AL
Sbjct: 886 ----------------------------DKKQKQLERLREQLNKLELQETDKDENKTIAL 917
Query: 528 GTSK 539
GTSK
Sbjct: 918 GTSK 921
[79][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 70.9 bits (172), Expect = 6e-11
Identities = 54/181 (29%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +++++K+ YN+ N+ VA LCNH R +P GH+
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDKLTNEDDSISEKILSYNRANRAVAILCNHQRAVPKGHEK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+K++ + +K+ +R + K A+ A E T Y
Sbjct: 138 SMEKIKEKIDAKRQAIKDAERQV-------KDAQRDAKHGSVKEKTVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
E+KR L+R +E+L KL +++ +T+ALGTS
Sbjct: 179 ------EKKRKL-------------------LERLKEQLTKLEIQETDRDENKTIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[80][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 214 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 273
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 274 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 309
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 310 ----KSRSVLEKKRRL-------------------LEKLQEQLAQLSVQATDKEENKQVA 346
Query: 525 LGTSK 539
LGTSK
Sbjct: 347 LGTSK 351
[81][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 321 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 380
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 381 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 416
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 417 ----KSRSVLEKKRRL-------------------LEKLQEQLAQLSVQATDKEENKQVA 453
Query: 525 LGTSK 539
LGTSK
Sbjct: 454 LGTSK 458
[82][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 70.9 bits (172), Expect = 6e-11
Identities = 68/219 (31%), Positives = 106/219 (48%), Gaps = 40/219 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T+++ LQ E T+ +K+ YN N+ VA LCNH RT+ +GH+
Sbjct: 644 GLTAKVFRTYNASWTMSQLLQKLEVEDRTMAEKIKLYNDCNREVAILCNHKRTVGAGHEA 703
Query: 177 QMQKLETR---------RAEAV-------------------------AWVKELKRGLAKW 254
QM+KL R R + + AWV+E ++ LAK
Sbjct: 704 QMEKLGDRIKGLKYQKWRTKMMMLDLDPKLKKKKGAEFFELDSDLDQAWVEEHQQFLAK- 762
Query: 255 NKGGKGAKAGAASSPPVEVTQY--MPVKPEILESMTADEKAQER-KRAADLPKVPLL-KS 422
K K A + +E + +P K E+ E + A + + + K+ KV K
Sbjct: 763 ELQEKIEKKFAKDNEKLEADKQAKLPAK-ELKERLKAVAELEAKFKKENKTKKVEAEGKG 821
Query: 423 MRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L + +++ +ER+ L +E + VALGTSK
Sbjct: 822 PSVEKLTTAVEKLDERIRTLEMQSADREGNKEVALGTSK 860
[83][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 70.9 bits (172), Expect = 6e-11
Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 21/200 (10%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP--GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T L + T+ +K+ YNK N++VA LCNH R P H
Sbjct: 621 GLTAKVFRTYNASSTFQRLLDEEDLTNATIQEKINAYNKANRMVAILCNHQRAAPKTHDQ 680
Query: 177 QMQKLETRRAEAVA-----------------WVKELKRGLAKWNKGGKGAKAGAASSPPV 305
M+K+ + A V W+++ + L K + K K + +
Sbjct: 681 SMEKMRYKAAPVVEMKKNKKYTQEESDIDDDWIEKHEESL-KEKEIEKAEKKFEKENEKL 739
Query: 306 EVTQYMPVKPEIL-ESMTADEKAQER-KRAADLPKVPLLKSMRCDQLKSNLKRAEERLAK 479
E K +L E + A E+ ER + K L + ++L+ +++ ++R+
Sbjct: 740 EAEGKDKQKKSVLKERIEAIEEEFERLAQERGTGKATLKRERPTEKLEEMIEKLDDRIKT 799
Query: 480 LTSDMEMKEDLQTVALGTSK 539
M +++ + VALGTSK
Sbjct: 800 FKLQMIDRDEGKEVALGTSK 819
[84][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 419 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 478
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 479 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 514
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 515 ----KSRSVLEKKRRL-------------------LEKLQEQLAQLSVQATDKEENKQVA 551
Query: 525 LGTSK 539
LGTSK
Sbjct: 552 LGTSK 556
[85][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 419 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 478
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 479 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 514
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 515 ----KSRSVLEKKRRL-------------------LEKLQEQLAQLSVQATDKEENKQVA 551
Query: 525 LGTSK 539
LGTSK
Sbjct: 552 LGTSK 556
[86][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 70.5 bits (171), Expect = 7e-11
Identities = 54/181 (29%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ D + V K+ YN+ N+ VA LCNH R P +
Sbjct: 507 GLTAKVFRTYNASITLQEQLKALTDAEDNVAAKILSYNRANRAVAILCNHQRATPKTFEK 566
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+ + + K E L+
Sbjct: 567 SMQNLQAK----------------------------------------IDAKKEQLDEAV 586
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ K R +A K + ++ K L++ EE+L KL+ KE+ + +ALGTS
Sbjct: 587 TELK---RAKADHKAKKDIKSKSNLEKKKKLLQKIEEQLMKLSVQATDKEENKQIALGTS 643
Query: 537 K 539
K
Sbjct: 644 K 644
[87][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 70.5 bits (171), Expect = 7e-11
Identities = 57/180 (31%), Positives = 77/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+ KVFRT+NAS+TL L D T K A Y+ NK VA LCNH + + H Q
Sbjct: 596 GLTIKVFRTYNASITLDSLLADTDTNLTTLQKKAKYDAANKEVAILCNHQKGVSKAHDEQ 655
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M KL ++ + + ++K+ NK
Sbjct: 656 MGKLNDKKKDLAKQITDMKK-----NK--------------------------------- 677
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D+K Q++K L +ER AKL MEMKE+L+TV+LGTSK
Sbjct: 678 DDKNQKKK----------------------LTALKERAAKLAIQMEMKEELKTVSLGTSK 715
[88][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 70.1 bits (170), Expect = 1e-10
Identities = 58/181 (32%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ +++ K+ YN+ N+ VA LCNH R P +
Sbjct: 588 GLTAKVFRTYNASITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNHQRAPPKTFEK 647
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K KGAKA +S
Sbjct: 648 SMQNLQTK-------IDEKQKQLSAARKQLKGAKAEHKASHD-----------------D 683
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 684 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 724
Query: 537 K 539
K
Sbjct: 725 K 725
[89][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment) n=1
Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 70.1 bits (170), Expect = 1e-10
Identities = 58/181 (32%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ +++ K+ YN+ N+ VA LCNH R P +
Sbjct: 601 GLTAKVFRTYNASITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNHQRAPPKTFEK 660
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K KGAKA +S
Sbjct: 661 SMQNLQTK-------IDEKQKQLSAARKQLKGAKAEHKASHD-----------------D 696
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 697 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 737
Query: 537 K 539
K
Sbjct: 738 K 738
[90][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 70.1 bits (170), Expect = 1e-10
Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +T+ +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 112 GLTAKVFRTYNASWTLQQQLDELTNADDTLAEKILSYNRANRAVAILCNHQRSVPKGHQK 171
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + K + + K A+ A E Y
Sbjct: 172 SMEKLKEK-------IDQKKENITDMQRQVKDAQKDAKHGSVKEKVVY------------ 212
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R ++L KL +++ +++ALGTS
Sbjct: 213 -------------------------DKKKKALERLRDQLMKLEVQETDRDENKSIALGTS 247
Query: 537 K 539
K
Sbjct: 248 K 248
[91][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 70.1 bits (170), Expect = 1e-10
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 321 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 380
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 381 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 416
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 417 ----KSRSVLEKKRWL-------------------LEKLQEQLAQLSVQATDKEENKQVA 453
Query: 525 LGTSK 539
LGTSK
Sbjct: 454 LGTSK 458
[92][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 70.1 bits (170), Expect = 1e-10
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS +
Sbjct: 321 GLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEK 380
Query: 177 QMQKLETR---RAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ L+T+ + E VA + EL+R A+ G G
Sbjct: 381 SMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDG------------------------ 416
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
E+KR L++ +E+LA+L+ KE+ + VA
Sbjct: 417 ----KSRSVLEKKRWL-------------------LEKLQEQLAQLSVQATDKEENKQVA 453
Query: 525 LGTSK 539
LGTSK
Sbjct: 454 LGTSK 458
[93][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 70.1 bits (170), Expect = 1e-10
Identities = 64/217 (29%), Positives = 99/217 (45%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 519 GLTAKVFRTYNASKTMQDQIDLIENEGTVAEKVVKFNAANRTVAILCNHQRTVSKNHSNT 578
Query: 180 MQKLETRRAEAVAWVK------------ELKRGLAKW--------------------NKG 263
+QK+ + E + W K +LK+ AK+ N+
Sbjct: 579 VQKINDKLKE-LMWQKIRLKKMILVLEPKLKKKDAKYFEEIDDLIKEDIEHIHHTIINRQ 637
Query: 264 GKGAKAGAASSPPVEVTQYMPV--KPEILESM---TADEKAQERKRAADLPKVPLLKSMR 428
+ + + P+ K +I E M T EK +++R P VP K+
Sbjct: 638 REQVQKKFERDNEKLKLEGKPLLTKKDIKEKMDKITELEKEYKQERKTGKPVVP--KNAT 695
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++LK ++ E R+ + ++ KED V+LGTSK
Sbjct: 696 VEKLKGQIETLENRILTTSFQLKDKEDNSEVSLGTSK 732
[94][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 70.1 bits (170), Expect = 1e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 583 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 642
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+T+ + K LA + K AKA A ++++
Sbjct: 643 SMMNLQTK-------IDAKKEQLADARRDLKSAKADA----------------KVMKDAK 679
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 680 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 719
Query: 537 K 539
K
Sbjct: 720 K 720
[95][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 69.7 bits (169), Expect = 1e-10
Identities = 60/185 (32%), Positives = 83/185 (44%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P +
Sbjct: 114 GLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEK 173
Query: 177 QMQ----KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ K+ET++A+ EL++
Sbjct: 174 SMQTLQKKIETKKAQVAEAQVELQKA---------------------------------- 199
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
+ R R PK L K R L + EE+LA+L + KE+ + VA
Sbjct: 200 -------ETDLRMRGDSKPKSFLQKQRR-------LLKLEEQLARLCAKATDKEENKQVA 245
Query: 525 LGTSK 539
LGT+K
Sbjct: 246 LGTAK 250
[96][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 69.7 bits (169), Expect = 1e-10
Identities = 60/185 (32%), Positives = 83/185 (44%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P +
Sbjct: 411 GLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEK 470
Query: 177 QMQ----KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ K+ET++A+ EL++
Sbjct: 471 SMQTLQKKIETKKAQVAEAQVELQKA---------------------------------- 496
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
+ R R PK L K R L + EE+LA+L + KE+ + VA
Sbjct: 497 -------ETDLRMRGDSKPKSFLQKQRR-------LLKLEEQLARLCAKATDKEENKQVA 542
Query: 525 LGTSK 539
LGT+K
Sbjct: 543 LGTAK 547
[97][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 69.7 bits (169), Expect = 1e-10
Identities = 56/182 (30%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L D TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 816 GLTAKVFRTYNASKTLQDQLDKLTDGDATVAEKLLAYNRANRAVAILCNHQRSVPKGHQK 875
Query: 177 QMQKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M+ L+ + RA+ A + ++++ K AK G+ + E +
Sbjct: 876 SMENLKEKIRAKRDA----IDDCESEYHDLKKAAKRGS-----------------VKEKV 914
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
AD+K ++ L+R +E+L KL +++ +T+AL T
Sbjct: 915 NADKKGKQ------------------------LERLKEQLKKLELQETDRDENKTIALST 950
Query: 534 SK 539
SK
Sbjct: 951 SK 952
[98][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 69.7 bits (169), Expect = 1e-10
Identities = 54/181 (29%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L D TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 882 GLTAKVFRTYNASKTLQSQLDLLTDGSATVAEKLLAYNRANRAVAILCNHQRSVPKGHQK 941
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ + + + + A+++ K AK G+ + E +
Sbjct: 942 SMDNLKEKIRAKRDNIDDCE---AEYHDLKKAAKRGS-----------------VKEKVN 981
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
AD+KA++ L+R +++L KL +++ +T+AL TS
Sbjct: 982 ADKKAKQ------------------------LERLKDQLKKLELQETDRDENKTIALSTS 1017
Query: 537 K 539
K
Sbjct: 1018 K 1018
[99][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 69.7 bits (169), Expect = 1e-10
Identities = 60/185 (32%), Positives = 83/185 (44%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P +
Sbjct: 412 GLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEK 471
Query: 177 QMQ----KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ K+ET++A+ EL++
Sbjct: 472 SMQTLQKKIETKKAQVAEAQVELQKA---------------------------------- 497
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
+ R R PK L K R L + EE+LA+L + KE+ + VA
Sbjct: 498 -------ETDLRMRGDSKPKSFLQKQRR-------LLKLEEQLARLCAKATDKEENKQVA 543
Query: 525 LGTSK 539
LGT+K
Sbjct: 544 LGTAK 548
[100][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 69.3 bits (168), Expect = 2e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 583 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 642
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++L+
Sbjct: 643 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVLKDAK 679
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 680 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 719
Query: 537 K 539
K
Sbjct: 720 K 720
[101][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 69.3 bits (168), Expect = 2e-10
Identities = 57/181 (31%), Positives = 78/181 (43%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L D ++VT K+ YN+ N+ VA LCNH R P
Sbjct: 258 GLTAKVFRTYNASSTLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDK 317
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
QM+ L+ + + +KE K+GL +K E S
Sbjct: 318 QMENLQEKIDKKHLDIKEAKKGL-------------------------KAIKSEYKNSRN 352
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
K K+A ++R E+LAKL KE+ + +ALGTS
Sbjct: 353 EKLKLAMEKKA------------------KQVERLVEQLAKLEMKATDKEENKEIALGTS 394
Query: 537 K 539
K
Sbjct: 395 K 395
[102][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 69.3 bits (168), Expect = 2e-10
Identities = 57/181 (31%), Positives = 78/181 (43%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L D ++VT K+ YN+ N+ VA LCNH R P
Sbjct: 697 GLTAKVFRTYNASSTLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDK 756
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
QM+ L+ + + +KE K+GL +K E S
Sbjct: 757 QMENLQEKIDKKHLDIKEAKKGL-------------------------KAIKSEYKNSRN 791
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
K K+A ++R E+LAKL KE+ + +ALGTS
Sbjct: 792 EKLKLAMEKKA------------------KQVERLVEQLAKLEMKATDKEENKEIALGTS 833
Query: 537 K 539
K
Sbjct: 834 K 834
[103][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 69.3 bits (168), Expect = 2e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 822 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 881
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++L+
Sbjct: 882 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVLKDAK 918
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 919 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 958
Query: 537 K 539
K
Sbjct: 959 K 959
[104][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 69.3 bits (168), Expect = 2e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 570 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 629
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++L+
Sbjct: 630 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVLKDAK 666
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 667 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 706
Query: 537 K 539
K
Sbjct: 707 K 707
[105][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 69.3 bits (168), Expect = 2e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 587 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 646
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++L+
Sbjct: 647 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVLKDAK 683
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 684 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 723
Query: 537 K 539
K
Sbjct: 724 K 724
[106][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 69.3 bits (168), Expect = 2e-10
Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIEEAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[107][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 69.3 bits (168), Expect = 2e-10
Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 47/226 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ ++ +K+ YN N+ VA LCNH RT+ + H Q
Sbjct: 651 GLTAKVFRTYNASYTMATLLKDLKSTGSIAEKIKDYNDANRKVAILCNHKRTVTASHASQ 710
Query: 180 MQKLETR---------RAEAV-------------------------AWVKE--------- 230
M+KL R R + + W+KE
Sbjct: 711 MEKLGDRIKGLKYQEWRVKQMMLDLDPKIKKKKGPAFFELDESLDQEWIKEHQDYLVEEQ 770
Query: 231 ---LKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLP 401
+K+ K N+ K A G P E+ + + E+ +++ A K + + + +
Sbjct: 771 RQKIKKKFEKDNE--KRAAEGEKEMKPKELEERL----EVAKALEAKFKRENKTKKVEAE 824
Query: 402 KVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K + ++L++ L + +R+ ++ E +E+ + VALGTSK
Sbjct: 825 G----KGVTIEKLENQLLKLSQRIENMSLQAEDRENNKEVALGTSK 866
[108][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 69.3 bits (168), Expect = 2e-10
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E V K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA K K AKA A ++++
Sbjct: 645 SMMNLQSK-------IDAKKDQLADARKDLKSAKADA----------------KVMKDAK 681
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 682 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[109][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 68.9 bits (167), Expect = 2e-10
Identities = 61/181 (33%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NASVTL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 599 GLTAKVFRTYNASVTLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 658
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+T+ + K LA + K AK
Sbjct: 659 SMMNLQTK-------IDAKKDQLANARRDLKSAK-------------------------- 685
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
AD K Q R A KV K K ++R EE+L KL +E+ + +ALGTS
Sbjct: 686 ADAKVQ---RDAKSKKVVETK-------KKAVQRLEEQLMKLEVQATDREENKQIALGTS 735
Query: 537 K 539
K
Sbjct: 736 K 736
[110][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 68.9 bits (167), Expect = 2e-10
Identities = 58/181 (32%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P +
Sbjct: 391 GLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEK 450
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K K AKA +S
Sbjct: 451 SMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKASHD-----------------D 486
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 487 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 527
Query: 537 K 539
K
Sbjct: 528 K 528
[111][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 68.9 bits (167), Expect = 2e-10
Identities = 58/181 (32%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P +
Sbjct: 623 GLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEK 682
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K K AKA +S
Sbjct: 683 SMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKASHD-----------------D 718
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 719 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 759
Query: 537 K 539
K
Sbjct: 760 K 760
[112][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 68.9 bits (167), Expect = 2e-10
Identities = 58/181 (32%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K K AKA +S
Sbjct: 645 SMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKASHD-----------------D 680
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 681 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[113][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 68.9 bits (167), Expect = 2e-10
Identities = 58/181 (32%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + E ++ L+ K K AKA +S
Sbjct: 645 SMQNLQTK-------IDEKQKQLSAARKQLKAAKAEHKASHD-----------------D 680
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+KA E KR A ++R EE+L KL +E+ + +ALGTS
Sbjct: 681 KSKKAVEVKRKA-------------------VQRIEEQLMKLQVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[114][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 68.9 bits (167), Expect = 2e-10
Identities = 51/181 (28%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L+ + ++ +K+ YN+ N+ VA LCNH R +P
Sbjct: 100 GLTAKVFRTYNASKTLQEQLELLTEADMSLPEKMLAYNRANRAVAILCNHQRAVPKTFDK 159
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
QM+ L+ + E A ++E K+ L + +++
Sbjct: 160 QMENLQKKMEEKEAQIRECKKELKQHKSDYNNSRS------------------------E 195
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D++ ERK K +++ E+++ KL KE+ + +ALGTS
Sbjct: 196 KDKQLLERK-------------------KKRMQQLEDQMKKLEVQATDKEENKQIALGTS 236
Query: 537 K 539
K
Sbjct: 237 K 237
[115][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 68.9 bits (167), Expect = 2e-10
Identities = 52/181 (28%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQITDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[116][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 68.9 bits (167), Expect = 2e-10
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIVDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLVKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[117][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 68.9 bits (167), Expect = 2e-10
Identities = 50/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +T +K+ YN+ N+ VA LCNH R++P GH
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNEDDTEAEKILSYNRANRAVAILCNHQRSVPKGHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ K E +
Sbjct: 138 SMEKLKE--------------------------------------------KIEQKKDAI 153
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+D + Q + D + + + + D+ K L+R +++L KL +++ +++ALGTS
Sbjct: 154 SDAEQQVKDAQRDAKRGSVKEKVVYDKKKKTLERLKDQLMKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[118][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 68.9 bits (167), Expect = 2e-10
Identities = 66/212 (31%), Positives = 102/212 (48%), Gaps = 38/212 (17%)
Frame = +3
Query: 18 VFRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 194
VFRT+NAS T+A L Q TV +KV YN N+ VA LCNH RT+ +GH QM+KL
Sbjct: 634 VFRTYNASYTMATLLKQMQATGTVHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKL- 692
Query: 195 TRRAEAVAW----VKELKRGLAKWNKGGKGAKAGAASSPPVE--VTQYM----------- 323
+ R + +++ +K++ L K KG + S E V Q+
Sbjct: 693 SERIKGLSYQKWRIKQMMIDLDPKIKKKKGPEFFQLDSDLDEEWVKQHQAFLVEEQRQKI 752
Query: 324 ---------PVKPEILESMTADEKAQERKRAADL----------PKVPLL-KSMRCDQLK 443
++ E + M A E Q + A +L KV + K M ++L+
Sbjct: 753 QKKFEKENEKLRAEGEKEMKAKELEQRLEAAKELEAKFKKENKTKKVEVEGKGMTIEKLE 812
Query: 444 SNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+NL + ++R+ ++ + KE+ + VALGTSK
Sbjct: 813 NNLAKLDQRIETMSLQAQDKEENKEVALGTSK 844
[119][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 68.6 bits (166), Expect = 3e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ +P + + K+ YN+ N+ VA LCNH R P +
Sbjct: 593 GLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEK 652
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A +
Sbjct: 653 SMMNLQSK-------IDAKKEQLADARRELKSAKADA--------------------KVR 685
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ + K ++R EE+L KL +E+ + +ALGTS
Sbjct: 686 RDEKSKK----------------TVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTS 729
Query: 537 K 539
K
Sbjct: 730 K 730
[120][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 68.6 bits (166), Expect = 3e-10
Identities = 55/181 (30%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 734 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 793
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+T+ + K LA + K AKA A V+ + + K
Sbjct: 794 SMMNLQTK-------IDAKKDQLADARRDLKSAKAEAKVRKDVKTKKVVETK-------- 838
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
K ++R EE+L KL +E+ + +ALGTS
Sbjct: 839 ----------------------------KKAVQRLEEQLMKLEVQATDREENKQIALGTS 870
Query: 537 K 539
K
Sbjct: 871 K 871
[121][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 68.6 bits (166), Expect = 3e-10
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 645 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVMKDAK 681
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 682 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[122][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 68.6 bits (166), Expect = 3e-10
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 378 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 437
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 438 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVMKDAK 474
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 475 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 514
Query: 537 K 539
K
Sbjct: 515 K 515
[123][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 68.6 bits (166), Expect = 3e-10
Identities = 34/68 (50%), Positives = 46/68 (67%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 823 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKGHQK 882
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 883 SMENLKEK 890
[124][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 68.6 bits (166), Expect = 3e-10
Identities = 52/181 (28%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIDEAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[125][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 68.6 bits (166), Expect = 3e-10
Identities = 52/181 (28%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIEDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[126][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 68.6 bits (166), Expect = 3e-10
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIVDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[127][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 68.6 bits (166), Expect = 3e-10
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQITDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[128][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 68.6 bits (166), Expect = 3e-10
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQITDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[129][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 68.6 bits (166), Expect = 3e-10
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL L DP TV +K+ YN+ N+ VA LCNH R +P H
Sbjct: 784 GLTAKVFRTFNASFTLQNQLAELTDPNMTVPEKMLAYNRANRAVAILCNHQRAVPKTHDK 843
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ + + +K E +E T
Sbjct: 844 SMSNLKEK----------------------------------------IRLKKEAVE--T 861
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ ++ KR + S+ D+ + L+R +++L KL +++ +T+ALGTS
Sbjct: 862 CQRELKDMKRGGSVK-----GSVDRDKKQKQLERLKDQLKKLELQETDRDENKTIALGTS 916
Query: 537 K 539
K
Sbjct: 917 K 917
[130][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 68.6 bits (166), Expect = 3e-10
Identities = 54/181 (29%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 583 GLTAKVFRTHNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 642
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+T+ + K LA + K AKA A ++++
Sbjct: 643 SMMNLQTK-------IDAKKEQLADARRDLKSAKADA----------------KVMKDAK 679
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 680 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 719
Query: 537 K 539
K
Sbjct: 720 K 720
[131][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 68.6 bits (166), Expect = 3e-10
Identities = 61/216 (28%), Positives = 98/216 (45%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ T+ +K+ YN N+ VA LCNH RT+ + H Q
Sbjct: 649 GLTAKVFRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQ 708
Query: 180 MQKLETR---------RAEAV-------------------------AWVKELKRGLAKWN 257
M+KL R R + + W+KE + L +
Sbjct: 709 MEKLGDRIKGLRYQEWRVKQMMLDLDPKIKKKKGSAFFELDESLDHEWIKEHQAYLVEEQ 768
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQER-KRAADLPKVPLL-KSMRC 431
+ K + V + E+ E + A ++ + + KR KV K +
Sbjct: 769 RQKIKKKFEKDNQKRVAEGEREMKAKELEERLEAAKELEAKFKRENKTKKVEAEGKGITI 828
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ L + +R+ ++ E KE+ + VALGTSK
Sbjct: 829 EKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSK 864
[132][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 68.6 bits (166), Expect = 3e-10
Identities = 61/216 (28%), Positives = 98/216 (45%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ T+ +K+ YN N+ VA LCNH RT+ + H Q
Sbjct: 649 GLTAKVFRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQ 708
Query: 180 MQKLETR---------RAEAV-------------------------AWVKELKRGLAKWN 257
M+KL R R + + W+KE + L +
Sbjct: 709 MEKLGDRIKGLRYQEWRVKQMMLDLDPKIKKKKGSAFFELDESLDHEWIKEHQAYLVEEQ 768
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQER-KRAADLPKVPLL-KSMRC 431
+ K + V + E+ E + A ++ + + KR KV K +
Sbjct: 769 RQKIKKKFEKDNQKRVAEGEREMKAKELEERLEAAKELEAKFKRENKTKKVEAEGKGITI 828
Query: 432 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ L + +R+ ++ E KE+ + VALGTSK
Sbjct: 829 EKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSK 864
[133][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 68.6 bits (166), Expect = 3e-10
Identities = 64/217 (29%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ +V +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 738 GLTAKVFRTYNASYTMATLLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQ 797
Query: 180 MQKLETR----------------------------------RAEAVAWVKELKRGLAKWN 257
M+K+ R ++ WVKE + L +
Sbjct: 798 MEKMSERIKGLRYQRWRLKQQMLDLDPSLKKKKGAKFFEMDEDISMEWVKEHQAFLLE-E 856
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERK--RAADLPKVPLL-KSMR 428
+ K K + + +K LE K E K R KV + KS
Sbjct: 857 QRQKIKKKFEKENEKLAAEGEKEMKASELEHRLEAVKEMENKFMRENKTGKVEVEGKSPS 916
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ + + E+R+ + + KED + VALGTSK
Sbjct: 917 VEKLEAAITKLEQRIETMELQAQDKEDNKEVALGTSK 953
[134][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 68.6 bits (166), Expect = 3e-10
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 645 SMMNLQSK-------IDAKKEQLADARRDLKSAKADA----------------KVMKDAK 681
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 682 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[135][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 68.2 bits (165), Expect = 4e-10
Identities = 41/98 (41%), Positives = 58/98 (59%), Gaps = 6/98 (6%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GLSAKVFRT+NAS+TL + L + G +VT K YN+ N+ VA LCNH R P
Sbjct: 532 GLSAKVFRTYNASITLQQQLNELTEEGASVTAKFLQYNRANRAVAILCNHQRAAPKTFDK 591
Query: 177 QMQ----KLETRRAEAVAWVKELKRGLAKWNKGGKGAK 278
QM+ KL+ ++ + A KE+K ++++ GK K
Sbjct: 592 QMENIVNKLKEKKKQMKAVKKEIKELKREYHEKGKSEK 629
[136][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 68.2 bits (165), Expect = 4e-10
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P +
Sbjct: 569 GLTAKVFRTYNASITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 628
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + K L+ + KGAKA A +
Sbjct: 629 SMQNLQTK-------IDAKKEQLSAAKRELKGAKADA--------------------KVR 661
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ + K ++R E++L KL +E+ + +ALGTS
Sbjct: 662 KDEKSKK----------------AVESKKKAVQRIEDQLMKLEVQATDREENKQIALGTS 705
Query: 537 K 539
K
Sbjct: 706 K 706
[137][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 68.2 bits (165), Expect = 4e-10
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P +
Sbjct: 569 GLTAKVFRTYNASITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 628
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ + K L+ + KGAKA A +
Sbjct: 629 SMQNLQTK-------IDAKKEQLSAAKRELKGAKADA--------------------KVR 661
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ + K ++R E++L KL +E+ + +ALGTS
Sbjct: 662 KDEKSKK----------------AVESKKKAVQRIEDQLMKLEVQATDREENKQIALGTS 705
Query: 537 K 539
K
Sbjct: 706 K 706
[138][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 68.2 bits (165), Expect = 4e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E V K+ YN+ N+ VA LCNH R P +
Sbjct: 576 GLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEK 635
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 636 SMMNLQSK-------IDAKKDQLADARRDLKSAKADA----------------KVMKDAK 672
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 673 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 712
Query: 537 K 539
K
Sbjct: 713 K 713
[139][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 68.2 bits (165), Expect = 4e-10
Identities = 61/215 (28%), Positives = 99/215 (46%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGH--- 170
GL+AKVFRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH
Sbjct: 486 GLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQT 545
Query: 171 ----KGQMQKLETRRAEAVAWVKELKRGLAK-----------WNKGGKGAKAGAASSPPV 305
++Q+LE ++ + +L + L K K + +
Sbjct: 546 VEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREI 605
Query: 306 EVTQYMPV---------KPEILESM-------TADEKAQERKRAADLPKVPLLKSMR-CD 434
E Q V K E+L DEK QE ++ +V L S +
Sbjct: 606 EKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVE 665
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++K+ +++ E+R+ + ++ KE+ V+LGTSK
Sbjct: 666 KIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSK 700
[140][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 68.2 bits (165), Expect = 4e-10
Identities = 61/215 (28%), Positives = 99/215 (46%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGH--- 170
GL+AKVFRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH
Sbjct: 510 GLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQT 569
Query: 171 ----KGQMQKLETRRAEAVAWVKELKRGLAK-----------WNKGGKGAKAGAASSPPV 305
++Q+LE ++ + +L + L K K + +
Sbjct: 570 VEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREI 629
Query: 306 EVTQYMPV---------KPEILESM-------TADEKAQERKRAADLPKVPLLKSMR-CD 434
E Q V K E+L DEK QE ++ +V L S +
Sbjct: 630 EKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVE 689
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++K+ +++ E+R+ + ++ KE+ V+LGTSK
Sbjct: 690 KIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSK 724
[141][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 68.2 bits (165), Expect = 4e-10
Identities = 63/217 (29%), Positives = 96/217 (44%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ +V +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 626 GLTAKVFRTYNASYTMATLLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQ 685
Query: 180 MQKLETR----------------------------------RAEAVAWVKELKRGLAKWN 257
M+K+ R ++ WVKE + L +
Sbjct: 686 MEKMSERIKGLRYQRWRLKQQMLDLDPSLKKKKGAKFFEMDEDISMEWVKEHQAYLLE-E 744
Query: 258 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQER--KRAADLPKVPLL-KSMR 428
+ K K + + +K LES K E K+ KV + KS
Sbjct: 745 QRQKIKKKFEKENEKLAAEGEKEMKASELESRLEAVKEMENKFKKENKTGKVDVEGKSSS 804
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ + + E+R+ + + KE+ + VALGTSK
Sbjct: 805 VEKLEAAITKLEQRIETMELQAQDKEENKEVALGTSK 841
[142][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae RepID=TOP1_YEAST
Length = 769
Score = 68.2 bits (165), Expect = 4e-10
Identities = 61/215 (28%), Positives = 99/215 (46%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGH--- 170
GL+AKVFRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH
Sbjct: 510 GLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQT 569
Query: 171 ----KGQMQKLETRRAEAVAWVKELKRGLAK-----------WNKGGKGAKAGAASSPPV 305
++Q+LE ++ + +L + L K K + +
Sbjct: 570 VEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREI 629
Query: 306 EVTQYMPV---------KPEILESM-------TADEKAQERKRAADLPKVPLLKSMR-CD 434
E Q V K E+L DEK QE ++ +V L S +
Sbjct: 630 EKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVE 689
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++K+ +++ E+R+ + ++ KE+ V+LGTSK
Sbjct: 690 KIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSK 724
[143][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 68.2 bits (165), Expect = 4e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E V K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 645 SMMNLQSK-------IDAKKDQLADARRDLKSAKADA----------------KVMKDAK 681
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 682 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[144][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 68.2 bits (165), Expect = 4e-10
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ P E V K+ YN+ N+ VA LCNH R P +
Sbjct: 585 GLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEK 644
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A ++++
Sbjct: 645 SMMNLQSK-------IDAKKDQLADARRDLKSAKADA----------------KVMKDAK 681
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ + +K+A ++R EE+L KL +E+ + +ALGTS
Sbjct: 682 TKKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTS 721
Query: 537 K 539
K
Sbjct: 722 K 722
[145][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 67.8 bits (164), Expect = 5e-10
Identities = 63/215 (29%), Positives = 95/215 (44%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 531 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSS 590
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKWNKGGK---------------------------GA 275
+QK+ + E + W K K+ + + K A
Sbjct: 591 VQKIHDKLKE-LEWHKIRTKKMILQLEPNLKTKDPDYFEELDDLSKEDTEHIHRALIERA 649
Query: 276 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQ-----ERKRAADLP--KVPLLKSMRCD 434
+ A E + +L +EK + E++ A +L K + KS+ +
Sbjct: 650 REAARKRFQRENDKLKIEDKPLLTEKDLEEKMEKVNELEKEYAEELKTGKPQIKKSVTVE 709
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+LKS + R+ T ++ KED V+LGTSK
Sbjct: 710 KLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSK 744
[146][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 67.8 bits (164), Expect = 5e-10
Identities = 56/182 (30%), Positives = 88/182 (48%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L D +V +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 864 GLTAKVFRTYNASKTLQNQLDLLTDSNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQK 923
Query: 177 QMQKLETR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M+ L+ + RA+ A + A+++ K AK G+ + E +
Sbjct: 924 SMENLKEKIRAKRDA----IDDCEAEYHDLKKAAKRGS-----------------VKERV 962
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
AD+K + L+R +++L KL +++ +T+ALGT
Sbjct: 963 IADKKGK------------------------ILERLKDQLKKLELQETDRDENKTIALGT 998
Query: 534 SK 539
SK
Sbjct: 999 SK 1000
[147][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 67.8 bits (164), Expect = 5e-10
Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +T+ +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTIAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQITDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKTLERLKEQLMKLEVMETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[148][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 67.8 bits (164), Expect = 5e-10
Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ E L P E +V +K+ YN N+ VA LCNH RT+ +GH
Sbjct: 458 GLTAKVFRTYNASKTMQEQLDLIPNEGSVAEKLLKYNAANRTVAILCNHQRTVTAGHAKS 517
Query: 180 MQKLETRRAEAVAWVKE-LKRGL 245
+ K + R E W KE LK+G+
Sbjct: 518 VAK-SSDRIEEFKWQKERLKKGI 539
[149][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 67.8 bits (164), Expect = 5e-10
Identities = 63/215 (29%), Positives = 95/215 (44%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 531 GLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSS 590
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKWNKGGK---------------------------GA 275
+QK+ + E + W K K+ + + K A
Sbjct: 591 VQKIHDKLKE-LEWHKIRTKKMILQLEPNLKTKDPDYFEELDDLSKEDTEHIHRALIERA 649
Query: 276 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQ-----ERKRAADLP--KVPLLKSMRCD 434
+ A E + +L +EK + E++ A +L K + KS+ +
Sbjct: 650 REAARKRFQRENDKLKIEDKPLLTEKDLEEKMEKVNELEKEYAEELKTGKPQIKKSVTVE 709
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+LKS + R+ T ++ KED V+LGTSK
Sbjct: 710 KLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSK 744
[150][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 67.4 bits (163), Expect = 6e-10
Identities = 56/181 (30%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P +
Sbjct: 573 GLTAKVFRTYNASITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 632
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ A + KR L K AKA A +
Sbjct: 633 SMQNLQTKIDAKKAQLSAAKREL-------KSAKADA--------------------KVR 665
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ A K ++R +++L KL +E+ + +ALGTS
Sbjct: 666 RDEKSKKAVEAK----------------KKAVQRIDDQLMKLEVQATDREENKQIALGTS 709
Query: 537 K 539
K
Sbjct: 710 K 710
[151][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 67.4 bits (163), Expect = 6e-10
Identities = 56/181 (30%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P +
Sbjct: 571 GLTAKVFRTYNASITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEK 630
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+T+ A + KR L K AKA A +
Sbjct: 631 SMQNLQTKIDAKKAQLSAAKREL-------KSAKADA--------------------KVR 663
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ A K ++R +++L KL +E+ + +ALGTS
Sbjct: 664 RDEKSKKAVEAK----------------KKAVQRIDDQLMKLEVQATDREENKQIALGTS 707
Query: 537 K 539
K
Sbjct: 708 K 708
[152][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 67.4 bits (163), Expect = 6e-10
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 6/85 (7%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+
Sbjct: 807 GLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEK 866
Query: 177 QM----QKLETRRAEAVAWVKELKR 239
M +K+ +R + KE K+
Sbjct: 867 SMGNLKEKIRVKREQVEQCQKEFKK 891
[153][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 67.4 bits (163), Expect = 6e-10
Identities = 62/227 (27%), Positives = 93/227 (40%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 623 GLTAKVFRTYNASWTFQEQLKNTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 682
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 683 FAKAEDKIRALKYQRLKLRLQLFSLNPKIKKKHPELAEDESDVDDEFMERHEAELLEKAL 742
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 743 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLSEIKAEFKELKKERKA-- 789
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ + ++L + + R +ER+A ++ ++ L+ VALGTSK
Sbjct: 790 KKIDAKRGATEEKLLAQVARIDERIATAKVQLQDRDKLKDVALGTSK 836
[154][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 67.4 bits (163), Expect = 6e-10
Identities = 57/176 (32%), Positives = 86/176 (48%), Gaps = 8/176 (4%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ T+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 636 GLTAKVFRTYNASYTMATLLKKMSATGTIPEKVKQYNDANREVAILCNHKRTVAASHANQ 695
Query: 180 MQKLETR--RAEAVAW-VKELKRGLAKWNKGGKGAKAGAASSPP----VEVTQYMPVKPE 338
M+KL R + W +K++ + K KGA ++ Q V+ E
Sbjct: 696 MEKLGDRIKGLQYQKWRIKQMMLDIDSKIKKKKGAAYFELDDDLDMEWIKEHQAFLVE-E 754
Query: 339 ILESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKE 506
+ + + + KR AD K M+ +L+ LK A+E AK + + K+
Sbjct: 755 LRQKIRKKFDKENEKRVADGE-----KEMKAKELEERLKAADELEAKYKKENKTKK 805
[155][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 67.4 bits (163), Expect = 6e-10
Identities = 56/185 (30%), Positives = 83/185 (44%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ +++T KV YN+ N+ VA LCNH R +P +
Sbjct: 412 GLTAKVFRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEE 471
Query: 177 QMQ----KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
MQ K+ET++A+
Sbjct: 472 SMQTLQKKIETKKAQ--------------------------------------------- 486
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
A+ + + +K DL KS Q + L + EE+LA+L + KE+ + VA
Sbjct: 487 ---VAEAQVELQKAETDLRMRGDSKSKSFLQKQQRLLKLEEQLARLCTKATDKEENKQVA 543
Query: 525 LGTSK 539
LGT+K
Sbjct: 544 LGTAK 548
[156][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 67.0 bits (162), Expect = 8e-10
Identities = 58/182 (31%), Positives = 81/182 (44%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPG-ETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GL+AKVFRT+NAS+TL L DP E V K+ YN+ N+ VA LCNH R P
Sbjct: 299 GLTAKVFRTYNASITLLNQLLELTDPDDENVASKILSYNRANRAVAVLCNHQRAAPKNFS 358
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
QM ++ + +++ +R + + K AK + Y K E
Sbjct: 359 EQMGRMNEK-------IEKKQRDIQDAKQETKSAK-----------SDYKHNKSE----- 395
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
A KA E K K ++R +E+L KL KE+ + +ALGT
Sbjct: 396 -AKRKAYEGK-------------------KKKVERLQEQLIKLEVQATDKEENKEIALGT 435
Query: 534 SK 539
SK
Sbjct: 436 SK 437
[157][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 67.0 bits (162), Expect = 8e-10
Identities = 57/181 (31%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NASVTL E L+ ++V K+ YN+ N+ VA LCNH R P +
Sbjct: 473 GLTAKVFRTYNASVTLQEQLRALTRAEDSVAAKILSYNRANRAVAILCNHQRATPKTFEK 532
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+ + ++ K+ +A+ K A+AG
Sbjct: 533 SMQNLQLK-------IEAKKKQVAEAKAELKQARAG------------------------ 561
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+ R D + L K R L++ EE+L +L++ KE+ + VALGTS
Sbjct: 562 ------HKCRGDDRSRSFLEKRERL------LEKLEEQLMRLSTQATDKEESKQVALGTS 609
Query: 537 K 539
K
Sbjct: 610 K 610
[158][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 67.0 bits (162), Expect = 8e-10
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P
Sbjct: 321 GLTAKVFRTYNASITLQQQLQELTDPEESMPSKILSYNRANRAVAILCNHQRAPPKTFDQ 380
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ S + Q + K E+ E+
Sbjct: 381 SMANLK--------------------------------SKIDAKKEQILLAKKELKEA-- 406
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
+K + K + L KV + K ++RAEE+L ++ +E+ + +AL TS
Sbjct: 407 --KKEAKEKESEKLNKV-------VESKKRGVQRAEEQLMRMEVQATDREENKQIALSTS 457
Query: 537 K 539
K
Sbjct: 458 K 458
[159][TOP]
>UniRef100_Q8X232 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8X232_CRYNE
Length = 270
Score = 67.0 bits (162), Expect = 8e-10
Identities = 62/227 (27%), Positives = 94/227 (41%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 56 GLTAKVFRTYNASWTFQEQLKKTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 115
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 116 FAKAEDKIRALKYQRLKLRLQLFSLDPKIKKKHPELAEDESDMDDEFMERHEAELLDKAL 175
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 176 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLSEIKAEFKELKKERKA-- 222
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ +S ++L + + + +ER+A ++ ++ L+ VALGTSK
Sbjct: 223 KKIDPKRSATGEKLLAQISKIDERIATAKVQLQDRDKLKDVALGTSK 269
[160][TOP]
>UniRef100_Q8WZF2 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZF2_CRYNE
Length = 270
Score = 67.0 bits (162), Expect = 8e-10
Identities = 62/227 (27%), Positives = 93/227 (40%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 56 GLTAKVFRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 115
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 116 FAKAEDKIRALKYQRLKLRLQLFSLNPKIKKKHPELAEDESDVDDEFMERHEAELLEKAL 175
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 176 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLSEIKAEFKELKKERKA-- 222
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ + ++L + + R +ER+A ++ ++ L+ VALGTSK
Sbjct: 223 KKIDPKRGATEEKLLAQIARIDERIATAKVQLQDRDKLKDVALGTSK 269
[161][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 67.0 bits (162), Expect = 8e-10
Identities = 61/224 (27%), Positives = 94/224 (41%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ T+ +KV YN N+ VA LCNH RT+ + H
Sbjct: 627 GLTAKVFRTYNASYTMARLLKSLKATGTIQEKVKAYNDANREVAILCNHKRTVAATHGAS 686
Query: 180 MQKLETR--------------------------------RAEAV--AWVK--------EL 233
+ K+ + R E + WVK E+
Sbjct: 687 IDKMNEKIKGLRYQVWRTKMMMIDVDPKIKKKKGAEYFERPEDLDAEWVKQHQDAEVDEM 746
Query: 234 KRGLAK--WNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
++ + K K A G P E+T + E+ + K + + P V
Sbjct: 747 RQKITKKFEKDNEKLAAEGEKEMKPKELTDRLEKVEELASKYKKENKTGKVEAEGKGPTV 806
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++N+ + +R+ + ME KE + VALGTSK
Sbjct: 807 --------EKLEANIDKINQRIENMRIQMEDKEGNKEVALGTSK 842
[162][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 67.0 bits (162), Expect = 8e-10
Identities = 62/227 (27%), Positives = 93/227 (40%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 586 GLTAKVFRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 645
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 646 FAKAEDKIRALKYQRLKLRLQLFSLNPKIKKKHPELAEDESDVDDEFMERHEAELLEKAL 705
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 706 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLSEIKAEFKELKKERKA-- 752
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ + ++L + + R +ER+A ++ ++ L+ VALGTSK
Sbjct: 753 KKIDPKRGATEEKLLAQIARIDERIATAKVQLQDRDKLKDVALGTSK 799
[163][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 67.0 bits (162), Expect = 8e-10
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 7/186 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + L +++ +K+ FYN+ N+ VA LCNH + P
Sbjct: 671 GLSAKVFRTYNASITLQKELDKMDTKEFQSIDEKILFYNRCNREVAILCNHQKAPPKNLA 730
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
M K++ + + + +++L R K K K + S + + ++ I
Sbjct: 731 ETMSKID-EKIQELRDLQDLCR--IKIGKTPKSQQEDIESREAERLPKL--IQLAITNKK 785
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLK----RAEERLAKLTSDMEMKEDLQTV 521
D++ +++ + D+ K KS K +K + EE++ K K++L+TV
Sbjct: 786 DKDKEKTDKEISFDV-KAAFEKSRTLPDAKGKIKEKIAKYEEQIKKQEILKTGKDELKTV 844
Query: 522 ALGTSK 539
ALGTSK
Sbjct: 845 ALGTSK 850
[164][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 66.6 bits (161), Expect = 1e-09
Identities = 53/180 (29%), Positives = 81/180 (45%), Gaps = 1/180 (0%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS+TL + + E + K+ YN+ N+ VA LCNH R P +
Sbjct: 567 GLTAKVFRTYNASITLQQQVSFFTADENIPAKILSYNRANRAVAILCNHQRAPPKTFEKS 626
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M L+T+ + K LA + K AKA A ++L+
Sbjct: 627 MMNLQTK-------IDAKKEQLADARRDLKSAKADA----------------KVLKDAKT 663
Query: 360 DEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ + +K+A ++R EE+L KL +E+ + +ALGTSK
Sbjct: 664 KKVVESKKKA--------------------VQRLEEQLMKLEVQATDREENKQIALGTSK 703
[165][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 66.6 bits (161), Expect = 1e-09
Identities = 60/188 (31%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ + ++V +K+ YN+ N+ VA LCNH R P
Sbjct: 438 GLTAKVFRTYNASITLQQQLKELTNESDSVAEKLLSYNRANRAVAILCNHQRAPPKTFDQ 497
Query: 177 QM----QKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
M K+E R+ + V ELK+ AK KG
Sbjct: 498 SMANLQSKIEARKEQLVLAKSELKQ--AKKEAKAKG------------------------ 531
Query: 345 ESMTADEKAQE---RKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQ 515
+AD K Q RK+ A +KR EE+L KL +E+ +
Sbjct: 532 ---SADAKLQALVVRKKMA-------------------VKRCEEQLLKLEVQATDREENK 569
Query: 516 TVALGTSK 539
+ALGTSK
Sbjct: 570 QIALGTSK 577
[166][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 66.6 bits (161), Expect = 1e-09
Identities = 52/181 (28%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNAEDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + +++ + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IEQKREQIEDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L+R +E+L KL +++ +++ALGTS
Sbjct: 179 -------------------------DKKKKMLERLKEQLIKLEVLETDRDENKSIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[167][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 66.6 bits (161), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + + + K K A+ A E Y
Sbjct: 138 SMEKLKEK-------IDQKREQITDAQKQVKDAQRDAKHGSVKEKVVY------------ 178
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K L++ +E+L KL +++ + +ALGTS
Sbjct: 179 -------------------------DKKKKMLEKLKEQLIKLEVQETDRDENKAIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[168][TOP]
>UniRef100_Q8WZG9 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZG9_CRYNE
Length = 270
Score = 66.6 bits (161), Expect = 1e-09
Identities = 62/227 (27%), Positives = 94/227 (41%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 56 GLTAKVFRTYNASWTFQEQLKKTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 115
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 116 FAKAEDKIRALKYQRLKLRLQLFSLNPKIKKKYPELAEDESDMDDEFMERHEAELLDKAL 175
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 176 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLNEIKAEFKELKKERKA-- 222
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ +S ++L + + + +ER+A ++ ++ L+ VALGTSK
Sbjct: 223 KKIDPKRSATEEKLLAQISKIDERIATAKVQLQDRDKLKDVALGTSK 269
[169][TOP]
>UniRef100_Q8WZG1 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZG1_CRYNE
Length = 270
Score = 66.6 bits (161), Expect = 1e-09
Identities = 62/227 (27%), Positives = 94/227 (41%), Gaps = 48/227 (21%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G
Sbjct: 56 GLTAKVFRTYNASWTFQEQLRKTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGS 115
Query: 180 MQKLETR------------------------------------------RAEAVAWVKEL 233
K E + R EA K L
Sbjct: 116 FAKAEDKIRALKYQRLKLRLQLFSLNPKIKKKHPELAEDESDMDDEFMERHEAELLDKAL 175
Query: 234 KRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADL 398
+ KW+ G G K E L + A+ K +++R A
Sbjct: 176 ENAKKKWDTDNVKLEGDGKKKKTKGE-----------LDERLSEIKAEFKELKKERKA-- 222
Query: 399 PKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K+ +S ++L + + + +ER+A ++ ++ L+ VALGTSK
Sbjct: 223 KKIDPKRSATEEKLLAQISKIDERIATAKVQLQDRDKLKDVALGTSK 269
[170][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 66.6 bits (161), Expect = 1e-09
Identities = 63/225 (28%), Positives = 98/225 (43%), Gaps = 46/225 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T+++ LQ TV +KV YN N+ VA LCNH RT+ + H+
Sbjct: 611 GLTAKVFRTYNASYTMSKLLQELKVTNATVHEKVKLYNDCNRQVAILCNHKRTVGASHEQ 670
Query: 177 QMQKL-----------------------ETRRAEAVA-----------WVKELKRGL--- 245
QM+KL + ++ + A WVK + L
Sbjct: 671 QMKKLVEQIKGLRYQKWRTKMMMLDLDPKLKKKKGAAYFELDEDLTEEWVKSHQEFLVED 730
Query: 246 --AKWNK-----GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPK 404
AK NK K G P E+ + + E+ + K ++ + P
Sbjct: 731 QKAKINKKFEKDNEKRIADGEKPLPASELKERLKAASELEAKFKKENKTKKVEAEGKGPS 790
Query: 405 VPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
V ++L++ L++ ++R+ L +E + VALGTSK
Sbjct: 791 V--------EKLEAALEKLDQRIKNLELQSADREGNKEVALGTSK 827
[171][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 66.6 bits (161), Expect = 1e-09
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+ KVFRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G
Sbjct: 560 GLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDE 619
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 278
MQKLE + + VKE + L K +GA+
Sbjct: 620 SMQKLEQKIKDKKKEVKEAEAAL----KSARGAE 649
[172][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 66.6 bits (161), Expect = 1e-09
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+ KVFRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G
Sbjct: 632 GLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDE 691
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAK 278
MQKLE + + VKE + L K +GA+
Sbjct: 692 SMQKLEQKIKDKKKEVKEAEAAL----KSARGAE 721
[173][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 66.2 bits (160), Expect = 1e-09
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ +P + + K+ YN+ N+ VA LCNH R P +
Sbjct: 584 GLTAKVFRTYNASITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEK 643
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA + K AKA A +
Sbjct: 644 SMMNLQSK-------IDAKKEQLADARRELKSAKADA--------------------KVR 676
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK+++ + K ++R EE+L KL +E+ + +AL TS
Sbjct: 677 RDEKSKK----------------AVESKKKAVQRIEEQLMKLEVQATDREENKQIALSTS 720
Query: 537 K 539
K
Sbjct: 721 K 721
[174][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 414 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 473
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 474 SMENLKEK 481
[175][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 807 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 866
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 867 SMENLKEK 874
[176][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 414 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 473
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 474 SMENLKEK 481
[177][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 413 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 472
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 473 SMENLKEK 480
[178][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 803 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 862
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 863 SMENLKEK 870
[179][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 66.2 bits (160), Expect = 1e-09
Identities = 36/81 (44%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L DP ++ DK+ YN+ N+ VA LCNH RT+
Sbjct: 378 GLTAKVFRTYNASYTLQEQLHQVIDPKMSIEDKILIYNRSNRAVAILCNHQRTVSKTFDK 437
Query: 177 QMQKLETRRAEAVAWVKELKR 239
QM L + + +KE K+
Sbjct: 438 QMSNLREKIEKKEQQLKEAKK 458
[180][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 802 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 861
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 862 SMENLKEK 869
[181][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 66.2 bits (160), Expect = 1e-09
Identities = 57/217 (26%), Positives = 99/217 (45%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T+ L G T+ +KV YN N+ VA LCNH RT+ +GH
Sbjct: 603 GLTAKVFRTYNASYTMGCVLNEMNASGGTIAEKVKAYNDANRKVAILCNHKRTVTAGHAN 662
Query: 177 QMQKLETR-----------------------RAEAVA-----------WVKELKRGLAKW 254
M+K+ R + + A W++E + L +
Sbjct: 663 AMEKMGERIKGLRYQKWRLKQQMLDLDPTLKKKKGAAFFEIDEDLDKEWIEEHQAFLIEE 722
Query: 255 NKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQER-KRAADLPKVPL-LKSMR 428
+ K + V + E+ E + A ++ +++ K+ KV +
Sbjct: 723 QRNKINKKFEKDNEKRVADGEKEMKVSELEERLQAVKELEKKFKKENKTGKVEAEARGAT 782
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++++ + ++R+ ++ + KED + VALGTSK
Sbjct: 783 VEKLENSINKIDQRVETMSVQAQDKEDNKEVALGTSK 819
[182][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 66.2 bits (160), Expect = 1e-09
Identities = 61/224 (27%), Positives = 97/224 (43%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ TV +KV YN N+ VA LCNH RT+ + H
Sbjct: 645 GLTAKVFRTYNASYTMARLLKEMKATGTVQEKVKAYNDANREVAILCNHKRTVAASHATS 704
Query: 180 MQKLETR--------------------------------RAEAV--AWVKE--------- 230
++K+ R R E + WVK+
Sbjct: 705 IEKMNERINGLRYQAWRTKMMMIDVDPKIKKKKGAEYFERPEDLDDEWVKQHQDAEVEEM 764
Query: 231 LKRGLAKWNKGGKGAKA-GAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
++ + K+ K + KA G E+ + + E+ + K + + P V
Sbjct: 765 RQKIIKKFEKDNEKLKADGEKELKQKELNERLEKAEELAAKYKKENKTGKIEAEGKGPTV 824
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++N+++ +R+ + ME KE + VALGTSK
Sbjct: 825 --------EKLEANVEKIVQRIENMKIQMEDKEGNKEVALGTSK 860
[183][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+
Sbjct: 805 GLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEK 864
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 865 SMENLKEK 872
[184][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 65.9 bits (159), Expect = 2e-09
Identities = 62/213 (29%), Positives = 100/213 (46%), Gaps = 34/213 (15%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L P E TV +K+ +N N+ VA LCNH +T+ H
Sbjct: 504 GLTAKVFRTYNASKTMDDQLALIPNEGTVAEKLVKFNAANRAVAILCNHQKTVSKTHGES 563
Query: 180 MQKLETRRAEAVAWVK--------ELKRGLAK--------WNKGGKGAKAGAASSPPVEV 311
+ K+E R E V W K +L+ L K ++ K K A+ +
Sbjct: 564 VGKIEDRINE-VVWQKWRHKRMLLDLEPKLLKKEPKLFEDLDELSKEEKTACANRLLEKD 622
Query: 312 TQYMPVKPE------ILESMTADEKAQERKRAADLPKV--PLLKSMR---------CDQL 440
++ K E + E K++ + DL LK ++ ++L
Sbjct: 623 SERWTKKFERDNEKLVAEKQKPKPKSELNAKLKDLADTNKQYLKEIKSNKVEGKGTVEKL 682
Query: 441 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++ +++ E R+ + ++ KED +VALGTSK
Sbjct: 683 RAQVEKLETRVTTMRMQLKDKEDNSSVALGTSK 715
[185][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 65.9 bits (159), Expect = 2e-09
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++ L+ + +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 624 GLTAKVFRTYNASHTMSTLLKDMKATGNIAEKVKAYNDANRKVAILCNHKRTVAASHANQ 683
Query: 180 MQKLETR----------------------------------RAEAVAWVKELKRGLA--- 248
M+K+ R + WVKE + L
Sbjct: 684 MEKMSERIKGLRYQRWRLKQQMLDLEPSLKKKKGAKYFEMDEDMDLEWVKEHQAFLVEEQ 743
Query: 249 ------KWNKGG-KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
K+ K K A G E+ + V ++ + + K + + P V
Sbjct: 744 RQKIQKKFEKDNEKLAAEGEKEMKATELESRLQVAKDLEKKFNKENKTGKVEAEGKAPTV 803
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D++++ + + E+R+ + + KE+ + VALGTSK
Sbjct: 804 --------DKIEAAITKLEQRIETMELQAQDKEENKEVALGTSK 839
[186][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 65.5 bits (158), Expect = 2e-09
Identities = 59/217 (27%), Positives = 101/217 (46%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGETVT--DKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GLSAKVFRT+NAS T+++ L+ ++ +K+ YN N+ VA LCNH RT+ + H+
Sbjct: 648 GLSAKVFRTYNASWTMSDLLKKLKNSDISMQEKIKLYNDCNRKVAILCNHKRTVGASHEA 707
Query: 177 QMQKLE--TRRAEAVAW-VKELKRGLAKWNKGGKGA-----------------KAGAASS 296
++K++ + + W +K++ L K KGA +A +
Sbjct: 708 AIEKMDDAVKGLKYQKWRLKQMILDLDPKQKKKKGADWFALDEELDEAWIQEHQAFLVAQ 767
Query: 297 PPVEVTQYMPVKPEILES-----MTADEKAQERKRAADLPK-----------VPLLKSMR 428
+++ + + E L S M E + + A DL K K
Sbjct: 768 ERIKIEKKFAKENEKLVSEGQKEMKTKELNERLQAATDLEKKFKKENKSKKVEAEGKGSS 827
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++ ++N+ + +ER+A + E +E + VALGTSK
Sbjct: 828 VEKFEANITKIDERIANMLLKREDREGNKEVALGTSK 864
[187][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 65.1 bits (157), Expect = 3e-09
Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+ KVFRT+NAS+TL L D TV +K+ YN+ N+ VA LCNH R++P GH+
Sbjct: 445 GLTTKVFRTYNASLTLQNQLDELTDEEATVAEKLLVYNRANRAVAILCNHQRSIPKGHQQ 504
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+ L + + +L+ A++N E+ S T
Sbjct: 505 IMENLRKKIHNKSNAINDLE---AEFN--------------------------ELKRSAT 535
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
A+++K A K L+R +++L KL + +E+ + VAL TS
Sbjct: 536 LSGTAKDKKIAECKGK--------------QLERLKDQLKKLKLEETNREENKCVALTTS 581
Query: 537 K 539
K
Sbjct: 582 K 582
[188][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 65.1 bits (157), Expect = 3e-09
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++ L+ T+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 621 GLTAKVFRTYNASHTMSTLLKDMKATGTIAEKVKAYNDANRQVAILCNHKRTVTASHANQ 680
Query: 180 MQKL----------------------------------ETRRAEAVAWVKELKRGL---- 245
M+K+ E + W+KE + L
Sbjct: 681 MEKMGERIKGLRYQRWRLKQQMLDLEPNLKKKKGAKFFEMDEDIDMEWIKEHQAFLLEEQ 740
Query: 246 -----AKWNKGG-KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
K++K K A G E+ + V ++ + + K + + P V
Sbjct: 741 RQKIQKKFDKDNEKLAAEGEKEMKAKELENRLEVVKDMEKKFNKENKTGKVEAEGKGPTV 800
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ +++ E+R+ + + KED + VALGTSK
Sbjct: 801 --------EKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSK 836
[189][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 65.1 bits (157), Expect = 3e-09
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 45/224 (20%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++ L+ T+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 621 GLTAKVFRTYNASHTMSTLLKDMKATGTIAEKVKAYNDANRQVAILCNHKRTVTASHANQ 680
Query: 180 MQKL----------------------------------ETRRAEAVAWVKELKRGL---- 245
M+K+ E + W+KE + L
Sbjct: 681 MEKMGERIKGLRYQRWRLKQQMLDLEPNLKKKKGAKFFEMDEDIDMEWIKEHQAFLLEEQ 740
Query: 246 -----AKWNKGG-KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKV 407
K++K K A G E+ + V ++ + + K + + P V
Sbjct: 741 RQKIQKKFDKDNEKLAAEGEKEMKAKELENRLEVVKDMEKKFNKENKTGKVEAEGKGPTV 800
Query: 408 PLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L++ +++ E+R+ + + KED + VALGTSK
Sbjct: 801 --------EKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSK 836
[190][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 65.1 bits (157), Expect = 3e-09
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 38/217 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGETVT--DKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GLSAKVFRT+NAS T+++ L+ ++ +K+ YN N+ VA LCNH RT+ + H+
Sbjct: 649 GLSAKVFRTYNASWTMSDLLKKLKNSDISMQEKIKLYNDCNRKVAILCNHKRTVGASHEA 708
Query: 177 QMQKLE--TRRAEAVAW-VKELKRGLAKWNKGGKGA-----------------KAGAASS 296
++K++ + + W +K++ + K KGA +A +
Sbjct: 709 AIEKMDDAVKGLKYQKWRLKQMILDIDPKQKKKKGADWFALDEELDESWIQEHQAFLVAQ 768
Query: 297 PPVEVTQYMPVKPEILES-----MTADEKAQERKRAADLPK-----------VPLLKSMR 428
+++ + + E L S M E + A DL K K
Sbjct: 769 ERIKIEKKFAKENEKLVSEGQKEMKTKELNERLHAATDLEKKFKKENKTKKVEAEGKGPS 828
Query: 429 CDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
D+ ++N+ + +ER+A + E +E + VALGTSK
Sbjct: 829 VDKFEANITKIDERIANMLLKREDREGNKEVALGTSK 865
[191][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 64.7 bits (156), Expect = 4e-09
Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 3/182 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ---GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GL+AKVFRTFNAS TL + L D G TV +K+ YN+ N+ VA LCNH R P +
Sbjct: 14 GLTAKVFRTFNASTTLQDQLNKLTSDDG-TVEEKILSYNRANRAVAILCNHQRAAPKTFE 72
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
MQ L+ + + ++E ++ E+ E+
Sbjct: 73 KSMQLLQEKIQKKKEQIEEARK--------------------------------ELKEAK 100
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGT 533
D+ K + + K CDQLK KL +E+ + +ALGT
Sbjct: 101 QVDKDTPSDKSSKLVEKKQKAVQRLCDQLK-----------KLQLQETDREENKVIALGT 149
Query: 534 SK 539
SK
Sbjct: 150 SK 151
[192][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 64.7 bits (156), Expect = 4e-09
Identities = 52/162 (32%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K
Sbjct: 403 GLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFK 462
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
QM +L T+ + ++ L K K A+ +E M + E LES
Sbjct: 463 LQMMQLTTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESY 516
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAK 479
+E+ +E + P ++S + + S K+AE K
Sbjct: 517 GTEEQKKEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 557
[193][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 64.7 bits (156), Expect = 4e-09
Identities = 52/162 (32%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K
Sbjct: 717 GLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFK 776
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
QM +L T+ + ++ L K K A+ +E M + E LES
Sbjct: 777 LQMMQLTTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESY 830
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAK 479
+E+ +E + P ++S + + S K+AE K
Sbjct: 831 GTEEQKKEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 871
[194][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 64.7 bits (156), Expect = 4e-09
Identities = 52/162 (32%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K
Sbjct: 403 GLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFK 462
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
QM +L T+ + ++ L K K A+ +E M + E LES
Sbjct: 463 LQMMQLTTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESY 516
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAK 479
+E+ +E + P ++S + + S K+AE K
Sbjct: 517 GTEEQKKEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 557
[195][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 64.3 bits (155), Expect = 5e-09
Identities = 36/84 (42%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P
Sbjct: 321 GLTAKVFRTYNASITLQQQLQELTDPEESIPAKILSYNRANRAVAILCNHQRAPPKTFDQ 380
Query: 177 QM----QKLETRRAEAVAWVKELK 236
M K++ ++ + + KELK
Sbjct: 381 SMANLKSKIDAKKEQILLAKKELK 404
[196][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 64.3 bits (155), Expect = 5e-09
Identities = 52/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K
Sbjct: 403 GLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFK 462
Query: 174 GQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 353
QM +L T+ + ++ L K K A+ +E M + E LES
Sbjct: 463 LQMMQLTTKS----EYTRKTLELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESY 516
Query: 354 TADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMK 503
+E+ +E + P ++S + + S K+A+ K + + K
Sbjct: 517 GTEEQKKEFEEIVAKRAAPRVRSEK--KSSSGTKKAKSASGKTRAATKKK 564
[197][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina
RepID=B2AY06_PODAN
Length = 904
Score = 64.3 bits (155), Expect = 5e-09
Identities = 33/68 (48%), Positives = 46/68 (67%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T++ LQ E T+ +K+ YN N+ VA +CNH RT+ + H+
Sbjct: 641 GLTAKVFRTYNASHTMSTLLQSLSVENRTMAEKIKLYNDCNREVAVICNHKRTVGAAHEA 700
Query: 177 QMQKLETR 200
QM+KL R
Sbjct: 701 QMEKLADR 708
[198][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 63.9 bits (154), Expect = 7e-09
Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L +P +T +K+ YN+ N+ VA LCNH R++P H
Sbjct: 808 GLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAK 867
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+ L+ + + K + +
Sbjct: 868 SMENLKAK----------------------------------------IEAKKQAINDAE 887
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D +++K+A D R +E+L KL KE+ + +ALGTS
Sbjct: 888 LDSTYEKKKKALD--------------------RLKEQLTKLEVQATDKEENKEIALGTS 927
Query: 537 K 539
K
Sbjct: 928 K 928
[199][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 63.9 bits (154), Expect = 7e-09
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLA------ECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPS 164
GLSAKVFRT+NAS TL E T ++KV YN N+ VA LCNH R++
Sbjct: 398 GLSAKVFRTYNASKTLQTELRKYEVSPAWRNLTASEKVVEYNNANREVAILCNHQRSVSK 457
Query: 165 GHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 344
+ Q++ + + V +K+ K+ L K IL
Sbjct: 458 AQETQLENITAK----VGMLKKQKKDLKK-----------------------------IL 484
Query: 345 ESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 524
+ +TA E A +P ++M +Q+ ++ +++K+ D++ K+D + V+
Sbjct: 485 KLLTAGE-------ADKIPTKKSPQTMTDEQVVKKIEAWNGKISKMEMDLKHKDDNKEVS 537
Query: 525 LGTSK 539
LGTSK
Sbjct: 538 LGTSK 542
[200][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 63.9 bits (154), Expect = 7e-09
Identities = 34/82 (41%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP---GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + P +V DK+A++NK N VA LCNH +++ H
Sbjct: 406 GLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHH 465
Query: 174 GQMQKLETRRAEAVAWVKELKR 239
M +L + + + LKR
Sbjct: 466 NLMHQLTQKSSYTRTIIDALKR 487
[201][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 63.9 bits (154), Expect = 7e-09
Identities = 34/82 (41%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDP---GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + P +V DK+A++NK N VA LCNH +++ H
Sbjct: 406 GLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHH 465
Query: 174 GQMQKLETRRAEAVAWVKELKR 239
M +L + + + LKR
Sbjct: 466 NLMHQLTQKSSYTRTIIDALKR 487
[202][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 63.5 bits (153), Expect = 9e-09
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRTFNAS TL + L + TV +K+ YN+ N+ VA LCNH R P +
Sbjct: 418 GLTAKVFRTFNASTTLQDQLNKLTSDDCTVEEKILSYNRANRAVAILCNHQRAAPKTFEK 477
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
MQ L+ + + ++E ++ E+ E+
Sbjct: 478 SMQLLQEKIQKKKEQIEEARK--------------------------------ELKEAKQ 505
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
D+ K + + K CDQLK KL +E+ + +ALGTS
Sbjct: 506 VDKDTPSDKSSKLVEKKQKAVQRLCDQLK-----------KLQLQETDREENKVIALGTS 554
Query: 537 K 539
K
Sbjct: 555 K 555
[203][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 63.5 bits (153), Expect = 9e-09
Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL + L + +++ +K+ YN+ N+ VA LCNH R++P H
Sbjct: 78 GLTAKVFRTYNASWTLQQQLDELTNADDSLAEKILSYNRANRAVAILCNHQRSVPKSHAK 137
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+KL+ + + + + +R + K AK G+ + E +
Sbjct: 138 SMEKLKEKIDQKREQIADAQRQV---KDAQKDAKHGS-----------------VKEKLV 177
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
++K K L + +++L KL +++ +T+ALGTS
Sbjct: 178 YEKK------------------------KKMLDKLKDQLKKLEVQETDRDENKTIALGTS 213
Query: 537 K 539
K
Sbjct: 214 K 214
[204][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 63.5 bits (153), Expect = 9e-09
Identities = 60/181 (33%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+ KVFRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G
Sbjct: 651 GLTVKVFRTYNASITLQEQLIKLTNPDDNVAAKILSYNRANRQVAILCNHQRAVSKGFDE 710
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M KLE + V LKR S + Q K E+ E+
Sbjct: 711 SMAKLEQK-------VMSLKR-----------------KSFFRLIFQIKDKKAEVKEA-- 744
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
E A + R A+ K + DQ K E+L KL K++ + +ALGTS
Sbjct: 745 --EAALKSARGAEKEKA----QKKYDQKK-------EQLKKLKIQRTDKDENKQIALGTS 791
Query: 537 K 539
K
Sbjct: 792 K 792
[205][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 63.5 bits (153), Expect = 9e-09
Identities = 56/181 (30%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L + + V K+ YN+ N+ VA LCNH R P +
Sbjct: 639 GLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEK 698
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+ + + K LA + K AKA A +
Sbjct: 699 SMMNLQGK-------IDAKKDQLADARREFKSAKADA--------------------KVR 731
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
DEK ++ L++S K ++R EE+L KL +E+ + +ALGTS
Sbjct: 732 RDEKTKK-----------LVESK-----KKAVQRIEEQLMKLEVQATDREENKQIALGTS 775
Query: 537 K 539
K
Sbjct: 776 K 776
[206][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 63.2 bits (152), Expect = 1e-08
Identities = 58/181 (32%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL E L+ + ++V +K+ YN+ N+ VA LCNH R P
Sbjct: 449 GLTAKVFRTYNASITLQEQLKELTNKSDSVAEKLLSYNRANRAVAILCNHQRAPPKTFDQ 508
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M L+++ + K LA G K AK A + E L+++
Sbjct: 509 SMATLQSK-------IDARKEQLALAKSGLKQAKKEAKAKGSSEFK---------LQTLV 552
Query: 357 ADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTS 536
ERK+AA RC+QL +A +R E+ + +ALGTS
Sbjct: 553 ------ERKKAA---------VKRCEQLLKMEIQATDR-----------EENKQIALGTS 586
Query: 537 K 539
K
Sbjct: 587 K 587
[207][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 63.2 bits (152), Expect = 1e-08
Identities = 53/179 (29%), Positives = 75/179 (41%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM 182
GL+AKVFRT+NAS+TL E +VA +CNH RT+ H QM
Sbjct: 1286 GLTAKVFRTYNASITLDE----------------------MVAIICNHQRTISKSHTAQM 1323
Query: 183 QKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 362
+L + E + LK LA+ KG PP+
Sbjct: 1324 TRLTEKIDEMKGVLNGLKTDLARAKKG----------KPPL------------------- 1354
Query: 363 EKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
K + KR P+ +L+ + + ++ K+ D + KEDL+TVALGTSK
Sbjct: 1355 -KDADGKRRNLTPEATY-------RLERKIAQTNAKIEKMERDKDTKEDLKTVALGTSK 1405
[208][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/81 (39%), Positives = 51/81 (62%), Gaps = 3/81 (3%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
LSAKVFRT+NAS+TL E + DP +++DK+ ++NK N VA+LCNH R++P
Sbjct: 430 LSAKVFRTYNASITLDEWFREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHV 489
Query: 177 QMQKLETRRAEAVAWVKELKR 239
+Q ++ + + + L+R
Sbjct: 490 SVQSIKYKLEDIKRTIDTLRR 510
[209][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/81 (39%), Positives = 51/81 (62%), Gaps = 3/81 (3%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
LSAKVFRT+NAS+TL E + DP +++DK+ ++NK N VA+LCNH R++P
Sbjct: 465 LSAKVFRTYNASITLDEWFREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHV 524
Query: 177 QMQKLETRRAEAVAWVKELKR 239
+Q ++ + + + L+R
Sbjct: 525 SVQSIKYKLEDIKRTIDTLRR 545
[210][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 63.2 bits (152), Expect = 1e-08
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 35/214 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + E TV +KV +N N+ VA LCNH RT+ H
Sbjct: 519 GLTAKVFRTYNASKTMQDQIDLIENEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGDS 578
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKG------AKAGAASSPPVEVTQYMPV---- 329
+Q++ + E + LK+ + + K + +E + +
Sbjct: 579 IQRINDKLKEFMWQKIRLKKMILQLEPKLKKKDPKYFEEIEDLIKEDIEHIHHTIIKRQR 638
Query: 330 ------------------KPEILESMTAD------EKAQERKRAADLPKVPLLKSMRCDQ 437
KP + ES D E +E K+ K + K+ ++
Sbjct: 639 EQVKKKLERDNEKLKLEGKPLLTESDIKDKLDKIDELEKEYKKELKTGKPIITKNATVEK 698
Query: 438 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
LK ++ E R+ ++ ++ KED V+LGTSK
Sbjct: 699 LKQQIETLENRILNVSFQLKDKEDNSEVSLGTSK 732
[211][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 63.2 bits (152), Expect = 1e-08
Identities = 64/216 (29%), Positives = 89/216 (41%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+A L+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 626 GLTAKVFRTYNASYTMATLLKDMKATGNNAEKVKAYNDANRRVAILCNHKRTVTASHANQ 685
Query: 180 MQKLETR--RAEAVAW-VKELKRGLAKWNKGGKGAKAGAASSPP-------------VEV 311
M+K+ R W +K+ L K KGAK E
Sbjct: 686 MEKMSERIKGLRYQRWRLKQQMLNLEPTLKKKKGAKFFEMDEDMDMDWVKEHQAFLLEEQ 745
Query: 312 TQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRCDQLKSN-------------- 449
Q + K E A E +E K + ++ +K M K N
Sbjct: 746 QQKIKKKFEKENEKLAAEGEKEMKASELDSRLEAVKEMELRFKKENKTGKVEAEGKSPSV 805
Query: 450 ------LKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ + E+R+ + + KED + VALGTSK
Sbjct: 806 ARIEAAITKLEQRIETMELQAQDKEDNKEVALGTSK 841
[212][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 62.8 bits (151), Expect = 2e-08
Identities = 36/71 (50%), Positives = 45/71 (63%), Gaps = 5/71 (7%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSG 167
GL+AKVFRT+NAS T++ L DP TV +KV YN N+ VA LCNH RT+ +
Sbjct: 644 GLTAKVFRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGAS 703
Query: 168 HKGQMQKLETR 200
H+ QM KL R
Sbjct: 704 HEQQMAKLGDR 714
[213][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 62.8 bits (151), Expect = 2e-08
Identities = 57/183 (31%), Positives = 81/183 (44%), Gaps = 4/183 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ----GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGH 170
GL+AKVFRT+NAS+TL + L GD + V K+ YN+ N+ VA LCNH R P
Sbjct: 602 GLTAKVFRTYNASITLQQQLNELTNGD--DNVPAKILSYNRANRAVAILCNHQRAPPKTF 659
Query: 171 KGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILES 350
+ M L+ G AK Q M + E L+S
Sbjct: 660 EKSMMNLQ----------------------GKIDAKK----------DQLMDARRE-LKS 686
Query: 351 MTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALG 530
AD K + +++ L + K ++R EE+L KL +E+ + +ALG
Sbjct: 687 AKADAKVKRDEKSKKL----------VESKKKAVQRVEEQLMKLEVQATDREENKQIALG 736
Query: 531 TSK 539
TSK
Sbjct: 737 TSK 739
[214][TOP]
>UniRef100_A4HB62 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania braziliensis
RepID=A4HB62_LEIBR
Length = 637
Score = 62.8 bits (151), Expect = 2e-08
Identities = 32/69 (46%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGET---VTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GLSAKVFRT+NAS+TL + P ++ + DK+A++NK N VA LCNH + + K
Sbjct: 403 GLSAKVFRTYNASITLDRWFKEKPVDSKWSIADKLAYFNKANTEVAILCNHQKAISKNFK 462
Query: 174 GQMQKLETR 200
QM +L T+
Sbjct: 463 LQMMQLTTK 471
[215][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 62.8 bits (151), Expect = 2e-08
Identities = 36/71 (50%), Positives = 45/71 (63%), Gaps = 5/71 (7%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSG 167
GL+AKVFRT+NAS T++ L DP TV +KV YN N+ VA LCNH RT+ +
Sbjct: 643 GLTAKVFRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGAS 702
Query: 168 HKGQMQKLETR 200
H+ QM KL R
Sbjct: 703 HEQQMAKLGDR 713
[216][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 62.4 bits (150), Expect = 2e-08
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLA-ECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGH 170
LSAKVFRT+NAS+TL E + DP E ++ V FYN N+ VA LCNH R P H
Sbjct: 456 LSAKVFRTYNASITLEQELCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQH 515
Query: 171 KGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILES 350
+ M++L+ + A+ A ++ L +G + G S V+
Sbjct: 516 EAGMERLKKKLADQEATLRGL--------EGRRDELLGKTVSKDVK-------------- 553
Query: 351 MTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALG 530
E E+K L KS D L +K + + + KED +TV+L
Sbjct: 554 ----EIIVEKK---------LEKSNNMDSLVRKIKSQKLAAERTKIQIADKEDNKTVSLT 600
Query: 531 TSK 539
TSK
Sbjct: 601 TSK 603
[217][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 62.0 bits (149), Expect = 3e-08
Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L T + + YN+ N+ VA LCNH R +P H+
Sbjct: 579 GLTAKVFRTYNASITLQQQLDKLTKDDSTAPELLLCYNRANRQVAILCNHQRAVPKSHEK 638
Query: 177 QMQKLETRRAEAVAWVKELKRGLAK 251
M+ L+ + +KE K L K
Sbjct: 639 SMENLKAKIKAKKTELKEAKEELEK 663
[218][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 62.0 bits (149), Expect = 3e-08
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 40/219 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++E L+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 611 GLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAAHAHQ 670
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M+K+ R LK+ + + K K GA E +K ++
Sbjct: 671 MEKMSERIKGQRYQKWRLKQMMLDLDPSLK-KKKGAQFFELDEDIDKEWIKEH--QAFLI 727
Query: 360 DEKAQERKRAADLPKVPLL----KSMRCDQLKSNLKRAEE-------------------- 467
+E+AQ+ K+ + LL K M+ +L++ L+ +E
Sbjct: 728 EEQAQKIKKKFEKDNEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRS 787
Query: 468 -----------RLAKLTSDMEM----KEDLQTVALGTSK 539
+L + +ME+ KED + VALGTSK
Sbjct: 788 PTVEKLEASITKLQQRIENMELQAQDKEDNKEVALGTSK 826
[219][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 62.0 bits (149), Expect = 3e-08
Identities = 56/214 (26%), Positives = 94/214 (43%), Gaps = 35/214 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + E TV +KVA +N N+ VA LCNH RT+ H
Sbjct: 522 GLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDS 581
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKG------AKAGAASSPPVEVTQYMPV---- 329
+Q++ + E + LK+ + + K + +E + +
Sbjct: 582 VQRINDKLKEFMWQKIRLKKMILQLEPKLKKKDPKYFEEIDDLIKEDIEHIHHTIIKRQR 641
Query: 330 ------------------KPEILESMTAD------EKAQERKRAADLPKVPLLKSMRCDQ 437
KP + ES D E +E ++ K + K+ ++
Sbjct: 642 EQAKKKLERDNEKLKLEGKPLLTESDIKDKLDKIDELEKEYQKELKTGKPIVTKNATVEK 701
Query: 438 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
LK ++ E ++ ++ ++ KED V+LGTSK
Sbjct: 702 LKQQIETLENKILNVSIQLKDKEDNSEVSLGTSK 735
[220][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 62.0 bits (149), Expect = 3e-08
Identities = 56/214 (26%), Positives = 94/214 (43%), Gaps = 35/214 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + E TV +KVA +N N+ VA LCNH RT+ H
Sbjct: 522 GLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDS 581
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKG------AKAGAASSPPVEVTQYMPV---- 329
+Q++ + E + LK+ + + K + +E + +
Sbjct: 582 VQRINDKLKEFMWQKIRLKKMILQLEPKLKKKDPKYFEEIDDLIKEDIEHIHHTIIKRQR 641
Query: 330 ------------------KPEILESMTAD------EKAQERKRAADLPKVPLLKSMRCDQ 437
KP + ES D E +E ++ K + K+ ++
Sbjct: 642 EQAKKKLERDNEKLKLEGKPLLTESDIKDKLDKIDELEKEYQKELKTGKPIVTKNATVEK 701
Query: 438 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
LK ++ E ++ ++ ++ KED V+LGTSK
Sbjct: 702 LKQQIETLENKILNVSIQLKDKEDNSEVSLGTSK 735
[221][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 62.0 bits (149), Expect = 3e-08
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 40/219 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++E L+ +KV YN N+ VA LCNH RT+ + H Q
Sbjct: 611 GLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAAHAHQ 670
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M+K+ R LK+ + + K K GA E +K ++
Sbjct: 671 MEKMSERIKGQRYQKWRLKQMMLDLDPSLK-KKKGAQFFELDEDIDKEWIKEH--QAFLI 727
Query: 360 DEKAQERKRAADLPKVPLL----KSMRCDQLKSNLKRAEE-------------------- 467
+E+AQ+ K+ + LL K M+ +L++ L+ +E
Sbjct: 728 EEQAQKIKKKFEKDNEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRS 787
Query: 468 -----------RLAKLTSDMEM----KEDLQTVALGTSK 539
+L + +ME+ KED + VALGTSK
Sbjct: 788 PTVEKLEASITKLQQRIENMELQAQDKEDNKEVALGTSK 826
[222][TOP]
>UniRef100_UPI000187C7E9 hypothetical protein MPER_03600 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187C7E9
Length = 238
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/65 (49%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGD--PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS T L G T+ +K+ YNK N++VA LCNH R++P H
Sbjct: 51 GLTAKVFRTYNASHTFQTLLDESHLEGATLQEKLNAYNKANRLVAILCNHQRSVPKTHDQ 110
Query: 177 QMQKL 191
MQK+
Sbjct: 111 SMQKM 115
[223][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 61.6 bits (148), Expect = 3e-08
Identities = 61/216 (28%), Positives = 104/216 (48%), Gaps = 37/216 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + L E +V +K+ YN N+ VA LCNH R++ H
Sbjct: 584 GLTAKVFRTYNASKTMQDQLDLIKNEGSVAEKILKYNAANRTVAILCNHQRSVAKTHAQS 643
Query: 180 MQKLETRRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASS-----PPVEVTQYMPVKPEI 341
+QK + + E + W K LKR + + +K + + VE + + +
Sbjct: 644 VQK-ASDKIEELEWQKVRLKRAILQLDKNERKKRPKFFEEIDDFRKEVEASIHERIIERE 702
Query: 342 LE------SMTADEKAQERKRAAD-------LPKVPLLKSMRCDQLK----------SNL 452
++ + D+K E++ D L KV L+ +LK +++
Sbjct: 703 IDKCHKKFARENDKKRFEKQELLDESVLKEWLEKVEELRQQYARELKTSVTEVKSSSNSI 762
Query: 453 KRAEERLAKL-----TSDMEM--KEDLQTVALGTSK 539
++ E+++ KL TS +++ KE+ V+LGTSK
Sbjct: 763 EKLEKQIEKLDQRIETSSIQLRDKEENSQVSLGTSK 798
[224][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 61.6 bits (148), Expect = 3e-08
Identities = 58/219 (26%), Positives = 98/219 (44%), Gaps = 40/219 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T+ + + E TV +KVA +N N+ VA LCNH RT+ H
Sbjct: 520 GLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDS 579
Query: 180 MQKLETRRAEAVAWVK------------ELKRGLAKW---------------------NK 260
+Q++ + + W K +LK+ +K+ +
Sbjct: 580 VQRIND-KLKKFMWQKIRLKKMILQLEPKLKKKDSKYFEEIDDLIKEDIEHIHHTIIKRQ 638
Query: 261 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD------EKAQERKRAADLPKVPLLKS 422
+ K + ++ + KP + ES D E +E ++ K + K+
Sbjct: 639 REQAKKKLERDNEKLK----LEGKPLLTESDIKDKLDKIDELEKEYQKELKTGKPIVTKN 694
Query: 423 MRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++LK ++ E R+ ++ ++ KED V+LGTSK
Sbjct: 695 ATVEKLKQQIETLENRILNVSIQLKDKEDNSEVSLGTSK 733
[225][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 61.2 bits (147), Expect = 5e-08
Identities = 60/200 (30%), Positives = 83/200 (41%), Gaps = 21/200 (10%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--------------DPGETVTDKVAFYNKQNKVVAELC 140
GL+AKVFRT+NAS+TL + L+ ++V +K+ YN+ N+ VA LC
Sbjct: 426 GLTAKVFRTYNASITLQQQLKELTNVIILFFFPCRLPESDSVAEKLLSYNRANRAVAILC 485
Query: 141 NHVRTLPSGHKGQM----QKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVE 308
NH R P M K+E R+ + V ELK+ AK KG
Sbjct: 486 NHQRAPPKTFDQSMANLQSKIEARKEQLVLAKSELKQ--AKKEAKAKG------------ 531
Query: 309 VTQYMPVKPEILESMTADEKAQE---RKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAK 479
+AD K Q RK+ A +KR EE+L K
Sbjct: 532 ---------------SADAKLQALVVRKKMA-------------------VKRCEEQLLK 557
Query: 480 LTSDMEMKEDLQTVALGTSK 539
L +E+ + +ALGTSK
Sbjct: 558 LEVQATDREENKQIALGTSK 577
[226][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 61.2 bits (147), Expect = 5e-08
Identities = 36/82 (43%), Positives = 51/82 (62%), Gaps = 5/82 (6%)
Frame = +3
Query: 6 LSAKVFRTFNASVTLA-ECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGH 170
LSAKVFRT+NAS+TL E + DP E ++ V FYN N+ VA LCNH R P H
Sbjct: 456 LSAKVFRTYNASITLEQELCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQH 515
Query: 171 KGQMQKLETRRAEAVAWVKELK 236
+ M++L+ + A+ A ++ L+
Sbjct: 516 EAGMERLKKKLADQEATLRGLE 537
[227][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 61.2 bits (147), Expect = 5e-08
Identities = 56/218 (25%), Positives = 93/218 (42%), Gaps = 39/218 (17%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ---GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHK 173
GL+AKVFRT+NAS T++ LQ + +KV YN N+ VA LCNH R++ + H
Sbjct: 642 GLTAKVFRTYNASYTMSTLLQKLHSKKNISDAEKVKIYNDCNRQVAILCNHKRSVGASHD 701
Query: 174 GQMQKLETR---------RAEAV-------------------------AWVKELKRGLAK 251
QM+KL R R + + WVKE + L +
Sbjct: 702 AQMKKLGDRILGLKYQQWRTKMMMIDLDPKLKKKKGAQFFERIPELTDEWVKEHQAFLVE 761
Query: 252 WNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL--KSM 425
+ K + V + + E+ E + A + + + K L + +
Sbjct: 762 EKRAAITKKFEKDNEKAVANGEKKMPEKELKERLKAASEMDAMYKKENKTKKVLAEGRGV 821
Query: 426 RCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
++L+ +K+ +ER+ + ++ + VALGTSK
Sbjct: 822 TVEKLEQQVKKLDERIRTMELQAADRDGNKEVALGTSK 859
[228][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 60.8 bits (146), Expect = 6e-08
Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 5/184 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECL-----QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSG 167
GL+AKVFRT+NAS TL + L +G + DK+ FY++ N+ VA LCNH +T+
Sbjct: 512 GLTAKVFRTYNASHTLQKELDKADEEGLDKMDLKDKLNFYDEANRNVAILCNHQKTVGKN 571
Query: 168 HKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 347
+ K+E R + KEL L K K G A E
Sbjct: 572 FDVMVGKMEQRINVYKDYEKELHTHLNKCKKNGVNA----------------------YE 609
Query: 348 SMTADEKAQERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTVAL 527
E+ + K + K P K ++++ +++ ++++ + + + KE + +AL
Sbjct: 610 KEVILEEKDDGKHKMFVKKFPGTK----EKIQEAIEKIKKKIDEEQNKKQSKEKNKEIAL 665
Query: 528 GTSK 539
GTSK
Sbjct: 666 GTSK 669
[229][TOP]
>UniRef100_B6KLS9 Voltage gated chloride channel domain-containing protein n=1
Tax=Toxoplasma gondii ME49 RepID=B6KLS9_TOXGO
Length = 1779
Score = 60.1 bits (144), Expect = 1e-07
Identities = 46/162 (28%), Positives = 68/162 (41%)
Frame = -2
Query: 525 APPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQSST 346
+PPS PPSS P + + P + S+ + ++ P ++PP P PS S+
Sbjct: 200 SPPSSSPPSSSPPS-SSTSPSPSSPPSSSPPSPSPPPSSPPSSSPPSSSPPSPSSPPPSS 258
Query: 345 PESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGGSPASASGPCA 166
P S + P+ + PP + P S P S+ P + +P P P SP+ +S P
Sbjct: 259 PPSSSSPSSSSPPPSSSPPSSSPPSSSSPSSSSPPPSSSPPPPSPPSSSTSPSPSSPP-- 316
Query: 165 HWAASARGCTVPPPPCSACCKMPPCPSPSRQGHLGGTQPGSP 40
S+ + PPP S PP SP P SP
Sbjct: 317 ----SSSPPSPSPPPSSPPSSSPPSSSPPSPPSPSSPPPSSP 354
[230][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 59.3 bits (142), Expect = 2e-07
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ + + V +K+ YN+ N+ VA LCNH R P
Sbjct: 349 GLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQ 408
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 275
M L+ + + K+ L + K KG+
Sbjct: 409 SMANLQAKIDSRKEQLDLAKKELKQAKKEAKGS 441
[231][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 59.3 bits (142), Expect = 2e-07
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS+TL + L+ + + V +K+ YN+ N+ VA LCNH R P
Sbjct: 427 GLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQ 486
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 275
M L+ + + K+ L + K KG+
Sbjct: 487 SMANLQAKIDSRKEQLDLAKKELKQAKKEAKGS 519
[232][TOP]
>UniRef100_C4Q6C7 DNA topoisomerase type I, putative n=1 Tax=Schistosoma mansoni
RepID=C4Q6C7_SCHMA
Length = 652
Score = 59.3 bits (142), Expect = 2e-07
Identities = 50/186 (26%), Positives = 81/186 (43%), Gaps = 7/186 (3%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L+ +P + K+ YN+ N+ VA LCNH R++P
Sbjct: 503 GLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAK 562
Query: 177 QMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 356
M+ L+ + + K E + +T
Sbjct: 563 SMENLQKK----------------------------------------IDAKREQISEIT 582
Query: 357 ADEKA-----QERKRAADLPKVPLLKSMRCDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 521
++ K + K+A+ K + ++LK L A+E L+KL +++ + +
Sbjct: 583 SEAKQIKADYKNHKQAS--------KKVAYEKLKKRLASAKEALSKLQLQATDRDENKEI 634
Query: 522 ALGTSK 539
AL TSK
Sbjct: 635 ALSTSK 640
[233][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 58.5 bits (140), Expect = 3e-07
Identities = 37/91 (40%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQ-----GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSG 167
GL+ KVFRT+NAS TL + L+ GD TV K A Y+ NK VA LCNH + +
Sbjct: 471 GLTIKVFRTYNASYTLNKLLKETTPAGD--STVPMKKAAYDAANKEVAVLCNHQKGVSKA 528
Query: 168 HKGQMQKLETRRAEAVAWVKELKRGLAKWNK 260
H QM+KL+ ++ + L+R NK
Sbjct: 529 HDAQMEKLQDKKKIIEKEIAALRRDKKDTNK 559
[234][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 58.5 bits (140), Expect = 3e-07
Identities = 63/219 (28%), Positives = 97/219 (44%), Gaps = 40/219 (18%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+AKVFRT+NAS T++E L+ +KV YN N+ VA LCNH RT+ + + Q
Sbjct: 611 GLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAVTRDQ 670
Query: 180 MQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA 359
M+K+ R LK+ + + K K GA E +K ++
Sbjct: 671 MEKMSERIKGQRYQKWRLKQMMLDLDPSLK-KKKGAQFFELDEDIDKEWIKEH--QAFLI 727
Query: 360 DEKAQERKRAADLPKVPLL----KSMRCDQLKSNLKRAEE-------------------- 467
+E+AQ+ K+ + LL K M+ +L++ L+ +E
Sbjct: 728 EEQAQKIKKKFEKDNEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRS 787
Query: 468 -----------RLAKLTSDMEM----KEDLQTVALGTSK 539
+L + +ME+ KED + VALGTSK
Sbjct: 788 PTVEKLEASITKLQQRIENMELQAQDKEDNKEVALGTSK 826
[235][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 58.2 bits (139), Expect = 4e-07
Identities = 46/152 (30%), Positives = 69/152 (45%)
Frame = +3
Query: 84 VTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKG 263
V + V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 782 VGELVQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKP 841
Query: 264 GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRCDQLK 443
K V+ Q P K + + M D A+ +L+
Sbjct: 842 PSKRKERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQ 881
Query: 444 SNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ LKR + L K+ ++K+D +TVALGTSK
Sbjct: 882 ALLKRRADHLLKI----KLKDDNKTVALGTSK 909
[236][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 58.2 bits (139), Expect = 4e-07
Identities = 46/152 (30%), Positives = 69/152 (45%)
Frame = +3
Query: 84 VTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKG 263
V + V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 782 VGELVQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKP 841
Query: 264 GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRCDQLK 443
K V+ Q P K + + M D A+ +L+
Sbjct: 842 PSKRKERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQ 881
Query: 444 SNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ LKR + L K+ ++K+D +TVALGTSK
Sbjct: 882 ALLKRRADHLLKI----KLKDDNKTVALGTSK 909
[237][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 58.2 bits (139), Expect = 4e-07
Identities = 46/152 (30%), Positives = 69/152 (45%)
Frame = +3
Query: 84 VTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKG 263
V + V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 782 VGELVQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKP 841
Query: 264 GKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRCDQLK 443
K V+ Q P K + + M D A+ +L+
Sbjct: 842 PSKRKERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQ 881
Query: 444 SNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+ LKR + L K+ ++K+D +TVALGTSK
Sbjct: 882 ALLKRRADHLLKI----KLKDDNKTVALGTSK 909
[238][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 58.2 bits (139), Expect = 4e-07
Identities = 55/215 (25%), Positives = 100/215 (46%), Gaps = 36/215 (16%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGH--- 170
GL+AKVFRT+NAS T+ + L + +V +K+ YN N+ VA LCNH R++ GH
Sbjct: 540 GLTAKVFRTYNASKTMQDQLDLIVNKGSVAEKMLRYNAANRTVAILCNHQRSVGKGHAEA 599
Query: 171 ---------KGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYM 323
+ + QK+ +RA KE+K+ + + G K S + + +
Sbjct: 600 VRKANEKIEELEWQKIRLKRAILQLEPKEMKKRPKFFAEIGDLTKEDEESIHKRIIEREI 659
Query: 324 P--------------------VKPEILESMTADEKAQERKRAADLP--KVPLLKSMR-CD 434
+K E L+ E+K + ++ +V + ++ +
Sbjct: 660 ERCHRKFQRENDKRKFDNEELIKEEELKEWLDKVSETEKKYSLEVETGEVEIKSTLNTVE 719
Query: 435 QLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 539
+L+ N+++ E+R+ + ++ KE+ V+LGTSK
Sbjct: 720 KLEKNIEKLEQRIQTSSIQLKDKEENSQVSLGTSK 754
[239][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 57.4 bits (137), Expect = 7e-07
Identities = 36/79 (45%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQ 179
GL+ KVFRT+NAS L + L+ +P +TV K A Y+ NK VA LCNH + H Q
Sbjct: 524 GLTIKVFRTYNASFVLNKLLKDTNPRDTVPLKKAAYDAANKEVAVLCNHQKGESKAHGAQ 583
Query: 180 MQKLETRRAEAVAWVKELK 236
M+KL ++ A KELK
Sbjct: 584 MEKLVDKKK---AMEKELK 599
[240][TOP]
>UniRef100_Q5BXE0 SJCHGC03473 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BXE0_SCHJA
Length = 238
Score = 57.4 bits (137), Expect = 7e-07
Identities = 30/68 (44%), Positives = 43/68 (63%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L+ +P + K+ YN+ N+ VA LCNH R++P
Sbjct: 154 GLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAK 213
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 214 SMENLQKK 221
[241][TOP]
>UniRef100_C4Q6C8 DNA topoisomerase type I, putative n=2 Tax=Schistosoma mansoni
RepID=C4Q6C8_SCHMA
Length = 587
Score = 57.4 bits (137), Expect = 7e-07
Identities = 30/68 (44%), Positives = 43/68 (63%), Gaps = 2/68 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 176
GL+AKVFRT+NAS TL E L+ +P + K+ YN+ N+ VA LCNH R++P
Sbjct: 503 GLTAKVFRTYNASRTLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAK 562
Query: 177 QMQKLETR 200
M+ L+ +
Sbjct: 563 SMENLQKK 570
[242][TOP]
>UniRef100_A7PAK3 Chromosome chr14 scaffold_9, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PAK3_VITVI
Length = 717
Score = 55.8 bits (133), Expect = 2e-06
Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 5/168 (2%)
Frame = -2
Query: 528 PAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQSS 349
P+PP+ PPS P P A P T A A +S P +PPP PS R S
Sbjct: 88 PSPPASPPPSPPASPPPSPPASPPPSPPTSAPPPAVNSTPPPVLSPPPPSEGSPSPRVSP 147
Query: 348 TPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGGSPASASG-- 175
P P+ PP + P + P S + + P P++ SP SG
Sbjct: 148 APPVGTPPS----PPAVSPSTPPPDNVPSPTS---SSSPPPPVASSPQNSPSPPPPSGSE 200
Query: 174 PCAHWAASARGCTVPPPPCSACCKMPPC---PSPSRQGHLGGTQPGSP 40
P + AR PPPP PP P+P GT SP
Sbjct: 201 PLSPPPTPARSTISPPPPSVPSSSSPPSISPPAPPSNSSDTGTPTSSP 248
[243][TOP]
>UniRef100_Q3AZB7 Translation initiation factor IF-2 n=1 Tax=Synechococcus sp. CC9902
RepID=IF2_SYNS9
Length = 1176
Score = 55.8 bits (133), Expect = 2e-06
Identities = 55/193 (28%), Positives = 74/193 (38%), Gaps = 28/193 (14%)
Frame = -2
Query: 528 PAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAP--------WANPPPVFSP 373
PA P+ P P + P A P GST AG T ATAP + P P +
Sbjct: 104 PAQPAASKPLQPSVKAVAPPARPAPAGSTSAGSTPNKPATAPARPTAATTTSTPRPAAAA 163
Query: 372 VPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPY-STWPAHA*APLPTQRPRHGG 196
PS S P+ P G P A + +P ++P + PA P+ +P
Sbjct: 164 APSRPAPSKPQGAPKPQVVG-KPSAPELVSKPTPATKPTGAAKPAIVSKPITAAKPAVVA 222
Query: 195 SPASA-------SGPCAHWAASARGCTVPPPPCSACCKMP------PCPSPSRQGHLGGT 55
PA+A + P A+S + PPP S P P +PSR G G
Sbjct: 223 KPAAAKPTIVKPTAPTPRPASSPAAASSAPPPASTPRPAPSRPTPRPAAAPSRPGAPQGQ 282
Query: 54 QP------GSPKR 34
+P G+P R
Sbjct: 283 KPQIVSRAGAPPR 295
[244][TOP]
>UniRef100_Q21D92 OmpA/MotB n=1 Tax=Rhodopseudomonas palustris BisB18
RepID=Q21D92_RHOPB
Length = 617
Score = 55.1 bits (131), Expect = 3e-06
Identities = 55/169 (32%), Positives = 65/169 (38%), Gaps = 6/169 (3%)
Frame = -2
Query: 528 PAPPSGG--PPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQ 355
PA P GG PP +P P A P A P A RTA A A PPP +P P
Sbjct: 64 PAGPGGGAAPPQAPPPAAAPPRAEPPA-------RTAPPPAATAPAAPPPAAAPRP---- 112
Query: 354 SSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGGSPASASG 175
TP + A PP+A P R + P + P AP P+ +P +
Sbjct: 113 --TPPAAA-------PPEA------PRRPTPPPAAAPQRPTAPPAATAPQRPAAPTQPAQ 157
Query: 174 PCAHWAASARGCTVPPPPCSACCKMPPCPSPSRQG----HLGGTQPGSP 40
P A AA T PP A P RQG G T PG+P
Sbjct: 158 PSAPTAAPPAAVTPPPGAAPAQRSAPGAGPAERQGLERRAPGATAPGAP 206
[245][TOP]
>UniRef100_B9QEP3 Chloride channel protein k, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9QEP3_TOXGO
Length = 1733
Score = 55.1 bits (131), Expect = 3e-06
Identities = 45/162 (27%), Positives = 73/162 (45%), Gaps = 1/162 (0%)
Frame = -2
Query: 525 APPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQSST 346
+P S PP S P P + P + S + T+ S ++ P ++PP SP + S++
Sbjct: 191 SPSSSSPPPSSSP----PPSSPPSPSSAPSSSTSPSPSSPPSSSPP---SPSSAPSSSTS 243
Query: 345 PESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGG-SPASASGPC 169
P + P+ + PP + + P S P S+ P+ + P P+ P SP+ +S P
Sbjct: 244 PSPSSPPSPSSPPPSSPPSSSPPSPSSPPSSSPPSPS--PPPSSPPSSSSTSPSPSSAPS 301
Query: 168 AHWAASARGCTVPPPPCSACCKMPPCPSPSRQGHLGGTQPGS 43
+ +S+ + PPP S PP PSP + P S
Sbjct: 302 SSPPSSSPSSSSPPPSSS-----PPPPSPPSSSPPSSSSPSS 338
[246][TOP]
>UniRef100_B9Q1D7 Chloride channel, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9Q1D7_TOXGO
Length = 1756
Score = 55.1 bits (131), Expect = 3e-06
Identities = 51/164 (31%), Positives = 74/164 (45%), Gaps = 3/164 (1%)
Frame = -2
Query: 525 APPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQSST 346
+PPS PPSS + P + S + +A SS+T+P + PP SP PS SS
Sbjct: 202 SPPSSSPPSSSPSSSSPPPSSSPPPSSPPSPSSAPSSSTSPSPSSPPSSSP-PS--PSSA 258
Query: 345 PESQA*PACTG*PPQA--EKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGG-SPASASG 175
P S P+ + PP + + P S P S+ P+ + P P+ P SP+ +S
Sbjct: 259 PSSSTSPSPSSPPPSSPPSSSSTSPSPSSAPSSSPPSPS--PPPSSPPSSSSTSPSPSSA 316
Query: 174 PCAHWAASARGCTVPPPPCSACCKMPPCPSPSRQGHLGGTQPGS 43
P + +S+ + PPP S PP PSP + P S
Sbjct: 317 PSSSPPSSSPSSSSPPPSSS-----PPPPSPPSSSPPSSSSPSS 355
[247][TOP]
>UniRef100_Q941M6 Topoisomerase I (Fragment) n=1 Tax=Oryza sativa RepID=Q941M6_ORYSA
Length = 105
Score = 54.3 bits (129), Expect = 6e-06
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 3 GLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNH 146
GL+AKVFRT+NAS+TL E L + + VT K+ Y K NK VA LCNH
Sbjct: 57 GLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAILCNH 105
[248][TOP]
>UniRef100_Q89X06 Blr0521 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89X06_BRAJA
Length = 745
Score = 54.3 bits (129), Expect = 6e-06
Identities = 53/169 (31%), Positives = 62/169 (36%), Gaps = 8/169 (4%)
Frame = -2
Query: 528 PAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRTACSSATAPWANPPPVFSPVPSHRQSS 349
P PP GP + P P P A P A TA + AP A P P +P P+ +
Sbjct: 178 PPPPPAGPAARPTPA---PTATPTPVAPPPAAPTARPGSPAPAATPAPTPTPAPT----A 230
Query: 348 TPESQA*PA---CTG*PPQAEKTRHQPWRLSRPYS-----TWPAHA*APLPTQRPRHGGS 193
TP A PA G PP P RP S + PA P PT P GG+
Sbjct: 231 TPAPTATPAPGSTPGAPPAGRPGAPPPG--VRPGSPPAAGSPPAPGATPAPTTTPAPGGT 288
Query: 192 PASASGPCAHWAASARGCTVPPPPCSACCKMPPCPSPSRQGHLGGTQPG 46
SG + A G P P + P P R G G PG
Sbjct: 289 ATPPSGRPGPASTPAPGAATPAPTATPAPGGALTPPPGRPG--AGPTPG 335