[UP]
[1][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum
RepID=TOP1_DICDI
Length = 893
Score = 226 bits (577), Expect = 6e-58
Identities = 104/172 (60%), Positives = 128/172 (74%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A +DG +E VGN+ +EPP LFLGRG HP TG +K+RI P DVTLN+G IP P+PG
Sbjct: 434 ATIDGFKEKVGNYMIEPPGLFLGRGQHPKTGMLKQRIMPSDVTLNIGEGEVIPPSPIPGE 493
Query: 196 NWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRK 375
W +I+HN+ VTWLA W++S+ GG+KYVWL+ S KG +D KFE AR LK+CI IRK
Sbjct: 494 KWKEIVHNNTVTWLAFWRESVNGGFKYVWLAPSSKIKGQADRKKFEVARGLKNCIGDIRK 553
Query: 376 EYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y+K + + E RQ + ALYLID LALRVGNEK ED+ADTVGCCSLRVEH+
Sbjct: 554 GYQKSFNDESTEKRQLAVALYLIDFLALRVGNEKGEDQADTVGCCSLRVEHI 605
[2][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 221 bits (563), Expect = 3e-56
Identities = 105/176 (59%), Positives = 132/176 (75%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ +DGR+E VGNFR+EPP LF GRGDHP TGK+K R+ PE V +N+G ++ IP P
Sbjct: 264 KYKYCFLDGRKEKVGNFRIEPPGLFRGRGDHPKTGKLKTRVVPEQVIINIGKDSVIPS-P 322
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
PGHNW ++ H++ VTWLA W +++ KYV+LSAGS+ KG SD K+EKAR+LK I
Sbjct: 323 PPGHNWKEVRHDNTVTWLATWNENVNNNVKYVFLSAGSSLKGQSDLKKYEKARELKLYID 382
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+IRK+YRK K EVRQR+TA+YLID ALR GNEK EDEADTVGCCSLR EH+
Sbjct: 383 NIRKQYRKELEDKLMEVRQRATAMYLIDLFALRAGNEKGEDEADTVGCCSLRYEHI 438
[3][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 219 bits (558), Expect = 1e-55
Identities = 102/177 (57%), Positives = 129/177 (72%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ VA VDGR E VGNFRVEPP LF GRG+HP GK+K+R+ P D+T+N+G N P+PE P
Sbjct: 147 KYKVAYVDGRPEPVGNFRVEPPGLFRGRGEHPKMGKIKKRVYPRDITINIGENEPVPEHP 206
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSI-TGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
PG W ++ H+ VTWLA WKD+I T YKYV+L A S FK SD AK+EKAR+LK I
Sbjct: 207 YPGQTWKEVKHDHTVTWLAYWKDTISTKDYKYVFLGATSTFKADSDLAKYEKARKLKEII 266
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+RK Y + W + + RQ A+Y IDKLALR G+EK EDEADTVGCC+L+VE++
Sbjct: 267 VDVRKNYERDWDSSDQRKRQMGVAMYFIDKLALRAGHEKDEDEADTVGCCTLKVENI 323
[4][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 218 bits (555), Expect = 2e-55
Identities = 101/175 (57%), Positives = 130/175 (74%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F V L++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ PE +T+N+G P+PE P
Sbjct: 264 FKVCLLNGRKEQVGNFRIEPPGLFRGRGAHPKTGKLKRRVMPEQITINIGKGVPVPEPPA 323
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG++ H++ V WLA W ++I KYV +A S+ KGMSD+ KFEKAR+LK +A+
Sbjct: 324 -GHKWGEVRHDNSVAWLAMWHENINNSIKYVLFAANSSLKGMSDYKKFEKARELKKHVAT 382
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ RQR+TA+YLID LALR G EK +DEADTVGCCSLR EH+
Sbjct: 383 IRKDYEKELKSEAMFERQRATAMYLIDVLALRAGGEKGDDEADTVGCCSLRYEHI 437
[5][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 216 bits (549), Expect = 1e-54
Identities = 100/171 (58%), Positives = 127/171 (74%)
Frame = +1
Query: 19 LVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHN 198
++DGR+E VGNFR+EPP LF GRG HP TG +KRR+ PE +T+N+G P+PE P+PGH
Sbjct: 321 ILDGRKEKVGNFRIEPPGLFRGRGSHPKTGSLKRRVYPEQITINIGEGVPVPE-PLPGHQ 379
Query: 199 WGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKE 378
W ++ H++ VTWLA W ++I KYV+L+AGS+ KG SD K+EK+R+LK I IRK
Sbjct: 380 WAEVKHDNTVTWLATWHENINNNVKYVFLAAGSSLKGQSDLKKYEKSRKLKDYIDDIRKG 439
Query: 379 YRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
YRK ++ RQR TA+YLID ALR GNEK EDEADTVGCCSLR EH+
Sbjct: 440 YRKDLKSELTVERQRGTAMYLIDVFALRAGNEKGEDEADTVGCCSLRYEHV 490
[6][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 215 bits (548), Expect = 1e-54
Identities = 101/177 (57%), Positives = 131/177 (74%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ A+++G + + N+ +E P LFLGRG HP TG VK+RI+ ED+T+N+G P+PE
Sbjct: 529 QKYGFAMINGHRQRISNWAIERPGLFLGRGAHPKTGLVKKRIEAEDITINIGKGVPVPE- 587
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W K++H+ V WLA WK++I G+KYVWL A SA KG SD KFE AR+LK I
Sbjct: 588 PPPGHKWCKVVHDDKVAWLAMWKENINNGFKYVWLHASSAVKGRSDMKKFEVARKLKDHI 647
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ E RQR+TA+YLID+LALRVGNEK ED ADTVGCCSLRVEH+
Sbjct: 648 EKIRKKYLKELGSEELEERQRATAIYLIDRLALRVGNEKDEDTADTVGCCSLRVEHV 704
[7][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 215 bits (547), Expect = 2e-54
Identities = 103/175 (58%), Positives = 129/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L DGR++ VGNFRVEPP LF GRG+HP TG+VK+R+ PE +T+N+G NA +PE P
Sbjct: 405 YMYCLWDGRKQKVGNFRVEPPGLFRGRGEHPKTGRVKKRVMPEQITINIGENAKVPEPPA 464
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W +I H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I
Sbjct: 465 -GHRWKEIKHDHEGTWLAMWQENINGAYKYVMLAANSDIKGQSDFKKFEKARELKKHIDR 523
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+YRK +K RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ +H+
Sbjct: 524 IRKDYRKDLNSKMMADRQRATAIYLIDQFALRAGNEKGEDEADTVGCCSLKFQHI 578
[8][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 214 bits (546), Expect = 2e-54
Identities = 102/173 (58%), Positives = 129/173 (74%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI+P D+T+N+G APIPECP+PG
Sbjct: 455 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGE 514
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+LK I IR
Sbjct: 515 RWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIR 574
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + +K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 575 SAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 627
[9][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 214 bits (546), Expect = 2e-54
Identities = 104/170 (61%), Positives = 128/170 (75%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DGR E VGNF+VEPP+LF GRG HP TGK+KRRI+PED+ LNLG APIP P GH W
Sbjct: 223 LDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRIRPEDIVLNLGEGAPIPP-PPSGHQW 281
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
G+I H++ V WLA W+++I G +KYV L+A S+ KG SD KFEKAR+LK I IRKEY
Sbjct: 282 GEIRHDNTVQWLAMWRENIFGSFKYVRLAANSSLKGQSDFKKFEKARELKKHIDRIRKEY 341
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
R + +K RQ++ A+YLID ALR G EK+E+EADTVGCCSLR EH+
Sbjct: 342 RNNFKSKLMVERQKAVAVYLIDVFALRAGGEKSEEEADTVGCCSLRYEHI 391
[10][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans
RepID=Q5KB99_CRYNE
Length = 881
Score = 214 bits (545), Expect = 3e-54
Identities = 105/175 (60%), Positives = 128/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ A VDGR+E VGNFR EPP LF GRG+HP G VK R++PED+ +N+G APIP +
Sbjct: 383 YLYANVDGRKEKVGNFRAEPPGLFKGRGEHPKKGTVKNRLRPEDIIINIGKEAPIPVPNI 442
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PG W I H++ VTWLA WK+++ G KYV+LSAGSA+KG SD AKFEKAR+L +
Sbjct: 443 PGQ-WKGIQHDNTVTWLAHWKENVNGNAKYVFLSAGSAWKGQSDRAKFEKARELIKHVDK 501
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y +K RQR+TALY ID+LALR GNEK EDEADTVGCCSLR EH+
Sbjct: 502 IRKDYTADLKSKVMADRQRATALYFIDRLALRAGNEKGEDEADTVGCCSLRYEHV 556
[11][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 214 bits (545), Expect = 3e-54
Identities = 102/169 (60%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G A +P P PGH W
Sbjct: 413 DGRKQKVGNFRVEPPALFRGRGEHPKTGRVKTRVQPEQITINIGKGAAVPP-PPPGHKWK 471
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+YR
Sbjct: 472 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRKDYR 531
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 532 KGLKDELTANRQRATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 580
[12][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 214 bits (544), Expect = 4e-54
Identities = 105/175 (60%), Positives = 128/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ A VDGR+E VGNFR EPP LF GRG+HP G VK R++PED+ +N+G APIP +
Sbjct: 346 YLYANVDGRKEKVGNFRAEPPGLFKGRGEHPKKGTVKNRLRPEDIIINIGKEAPIPVPNI 405
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PG W I H++ VTWLA WK+++ G KYV+LSAGSA+KG SD AKFEKAR+L +
Sbjct: 406 PGQ-WKGIQHDNTVTWLAHWKENVNGNAKYVFLSAGSAWKGQSDRAKFEKARELIKHVDK 464
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y +K RQR+TALY ID+LALR GNEK EDEADTVGCCSLR EH+
Sbjct: 465 IRKDYTADLKSKIMADRQRATALYFIDRLALRAGNEKGEDEADTVGCCSLRYEHV 519
[13][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 213 bits (543), Expect = 5e-54
Identities = 100/173 (57%), Positives = 132/173 (76%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI+P D+T+N+G APIPECP+PG
Sbjct: 494 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIKPSDITINIGKGAPIPECPIPGE 553
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I+ +KYV+L+A SA KG SD K+EK+R+LK + IR
Sbjct: 554 SWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSALKGQSDKEKYEKSRKLKHHVHKIR 613
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + +K K +Q + A YLIDKLALR GNEK EDEA+TVGCC+L+V+++
Sbjct: 614 DTYTKDFRSKDKTKKQIAVATYLIDKLALRAGNEKDEDEAETVGCCTLKVDNV 666
[14][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 213 bits (543), Expect = 5e-54
Identities = 101/173 (58%), Positives = 129/173 (74%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRGDHP GK+K RI P D+ +N+G +AP+PECP+PG
Sbjct: 81 AVVDGVKEKVGNFRVEPPGLFRGRGDHPKMGKLKTRILPHDIVINIGKDAPVPECPIPGQ 140
Query: 196 NWGKIIHNSCVTWLAGWKDSITG-GYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA WKD I +KYV+L+A S+ KG SD K+EKAR LK I +IR
Sbjct: 141 KWKEVRHDNTVTWLAYWKDPINDKEFKYVFLAASSSLKGQSDMLKYEKARTLKDYIDNIR 200
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ Y K +++ +Q + A YLID+LALR GNEK EDEADTVGCCSL+VEH+
Sbjct: 201 RTYTKDFSSSDPTKQQIAVATYLIDRLALRAGNEKDEDEADTVGCCSLKVEHV 253
[15][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 213 bits (543), Expect = 5e-54
Identities = 100/173 (57%), Positives = 132/173 (76%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI+P D+T+N+G APIPECP+PG
Sbjct: 494 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIKPSDITINIGKGAPIPECPIPGE 553
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I+ +KYV+L+A SA KG SD K+EK+R+LK + IR
Sbjct: 554 SWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSALKGQSDKEKYEKSRKLKHHVHKIR 613
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + +K K +Q + A YLIDKLALR GNEK EDEA+TVGCC+L+V+++
Sbjct: 614 DTYTKDFRSKDKTKKQIAVATYLIDKLALRAGNEKDEDEAETVGCCTLKVDNV 666
[16][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 213 bits (542), Expect = 7e-54
Identities = 104/175 (59%), Positives = 128/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F +DGR E VGNFRVEPP+LF GRG HP TGK+KRR+ PED+ LNL NAPIP P
Sbjct: 300 FKFCELDGRREQVGNFRVEPPDLFRGRGAHPKTGKLKRRVYPEDIVLNLDRNAPIPAVP- 358
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ V WLA W+++I+ +KYV L+A S+ KG SD KFEKAR+LK I S
Sbjct: 359 EGHKWGEIKHDNTVQWLAMWRENISNSFKYVRLAANSSLKGQSDFKKFEKARELKKYIDS 418
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+YR +K RQ++ A+YLID ALR G EK++DEADTVGCCSLR EH+
Sbjct: 419 IRKDYRTNLKSKLMLERQKAVAIYLIDVFALRAGGEKSDDEADTVGCCSLRYEHV 473
[17][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 213 bits (541), Expect = 9e-54
Identities = 101/173 (58%), Positives = 131/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRIQP D+T+N+G AP+PECP+PG
Sbjct: 499 AVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIQPSDITINIGKGAPVPECPIPGE 558
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W +I H++ VTWLA W D I+ +KYV+L+A S+ KG SD K+EK+R+LK I IR
Sbjct: 559 SWKEIKHDNTVTWLAFWNDPISQKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGHIQRIR 618
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V+++
Sbjct: 619 ENYTKDFKNKDVTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNV 671
[18][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 213 bits (541), Expect = 9e-54
Identities = 102/173 (58%), Positives = 130/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A VDG++E VGNFRVEPP LF GRG+HP GK+K+RI+P D+T+N+G +APIPECPVPG
Sbjct: 486 AWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGE 545
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S KG+SD K+EKAR LK I IR
Sbjct: 546 RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIR 605
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K +A+K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 606 AAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 658
[19][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 213 bits (541), Expect = 9e-54
Identities = 100/169 (59%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P PGH W
Sbjct: 415 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVP-VPPPGHKWK 473
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG+SD+ KFEKAR+LK I IRK+Y+
Sbjct: 474 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGLSDYKKFEKARELKKHIDRIRKDYK 533
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 534 KGLKHELMSERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 582
[20][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 213 bits (541), Expect = 9e-54
Identities = 100/169 (59%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P PGH W
Sbjct: 415 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVP-VPPPGHKWK 473
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG+SD+ KFEKAR+LK I IRK+Y+
Sbjct: 474 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGLSDYKKFEKARELKKHIDRIRKDYK 533
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 534 KGLKHELMSERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 582
[21][TOP]
>UniRef100_A6R590 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6R590_AJECN
Length = 651
Score = 213 bits (541), Expect = 9e-54
Identities = 100/169 (59%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P PGH W
Sbjct: 415 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVP-VPPPGHKWK 473
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+I H+ TWLA W++++ G YKYV L+A S KG+SD+ KFEKAR+LK I IRK+Y+
Sbjct: 474 EIKHDQEGTWLAMWQENVNGNYKYVMLAANSDIKGLSDYKKFEKARELKKHIDRIRKDYK 533
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 534 KGLKHELMSERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKFEHV 582
[22][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 212 bits (540), Expect = 1e-53
Identities = 101/173 (58%), Positives = 130/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI P D+T+N+G N+ IPECP+PG
Sbjct: 436 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIHPSDITINIGKNSQIPECPIPGE 495
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+LK+ I IR
Sbjct: 496 SWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKNYIKDIR 555
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + +K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 556 ATYTKDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 608
[23][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 212 bits (540), Expect = 1e-53
Identities = 103/176 (58%), Positives = 129/176 (73%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F +DGR+E VGNFRVEPP+LF GRG HP TGK+KRR+ PED+ LNL +APIP P
Sbjct: 244 KFKFCELDGRKEQVGNFRVEPPDLFRGRGAHPKTGKLKRRVYPEDIILNLSKDAPIPPAP 303
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH+WG+I H++ V WLA WK++I G +KYV L+A S+ G SD KFEKAR+LK I
Sbjct: 304 -QGHHWGEIRHDNTVQWLAMWKENIFGSFKYVRLAANSSLNGQSDLKKFEKARELKKYIG 362
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+YR+ + +K RQ++ A Y ID ALR G EK+EDEADTVGCCSLR EH+
Sbjct: 363 DIRKDYRESFKSKIMLERQKAVATYFIDVFALRAGGEKSEDEADTVGCCSLRFEHV 418
[24][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 211 bits (538), Expect = 2e-53
Identities = 100/170 (58%), Positives = 128/170 (75%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DGR E VGNF+VEPP+LF GRG HP TGK+KRR+ PED+ LNL +AP+P P GH W
Sbjct: 251 LDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAP-EGHKW 309
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
G+I H++ V WLA W+++I +KYV L+A S+ KG SD+ KFEKARQLKS I +IR++Y
Sbjct: 310 GEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDY 369
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ +K RQ++ A+YLID ALR G EK+EDEADTVGCCSLR EH+
Sbjct: 370 TRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHV 419
[25][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 211 bits (538), Expect = 2e-53
Identities = 100/169 (59%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG VK R+QPE +T+N+G +AP+P P GH W
Sbjct: 402 DGRKQKVGNFRVEPPALFRGRGEHPKTGTVKTRVQPEQITINIGKDAPVP-APPEGHRWK 460
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W++++ G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 461 EVRHDQEGTWLAMWQENVNGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIDRIRKDYK 520
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 521 KGLKDELMVNRQRATAVYLIDQFALRAGNEKGEDEADTVGCCSLKFEHV 569
[26][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 211 bits (538), Expect = 2e-53
Identities = 100/176 (56%), Positives = 128/176 (72%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DGR+E VGNFR+EPP LF GRG+HP G +K+R+ PED+T+N+G A IP
Sbjct: 381 KYKTCVMDGRKEKVGNFRIEPPGLFRGRGEHPKKGSLKKRVYPEDITINIGKEAKIPVPN 440
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
+PG W K+IH++ VTWLA W ++I +KYV+L+AGS KG SD KFEKAR+LK I
Sbjct: 441 IPG-KWKKVIHDNTVTWLATWTENINNSHKYVFLAAGSRLKGQSDMQKFEKARELKDHIE 499
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y + K RQR+TA+Y IDKLALR GNEK EDEADTVGCCSLR EH+
Sbjct: 500 KIRADYTEDLRNKVMAHRQRATAMYFIDKLALRAGNEKGEDEADTVGCCSLRCEHV 555
[27][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 211 bits (538), Expect = 2e-53
Identities = 100/170 (58%), Positives = 128/170 (75%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DGR E VGNF+VEPP+LF GRG HP TGK+KRR+ PED+ LNL +AP+P P GH W
Sbjct: 275 LDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAP-EGHKW 333
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
G+I H++ V WLA W+++I +KYV L+A S+ KG SD+ KFEKARQLKS I +IR++Y
Sbjct: 334 GEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDY 393
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ +K RQ++ A+YLID ALR G EK+EDEADTVGCCSLR EH+
Sbjct: 394 TRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHV 443
[28][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 211 bits (537), Expect = 3e-53
Identities = 100/170 (58%), Positives = 128/170 (75%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DGR E VGNF+VEPP+LF GRG HP TGK+KRR+ PED+ LNL +AP+P P GH W
Sbjct: 275 LDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAP-EGHKW 333
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
G+I H++ V WLA W+++I +KYV L+A S+ KG SD+ KFEKARQLKS I +IR++Y
Sbjct: 334 GEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDY 393
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ +K RQ++ A+YLID ALR G EK+EDEADTVGCCSLR EH+
Sbjct: 394 TRNLKSKLMLERQKAVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHV 443
[29][TOP]
>UniRef100_A4HB62 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania braziliensis
RepID=A4HB62_LEIBR
Length = 637
Score = 210 bits (535), Expect = 4e-53
Identities = 100/169 (59%), Positives = 121/169 (71%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR E V NFRVEPP LF GRG HPL GK+K R+QPE +T+N+G A +P P GH WG
Sbjct: 170 DGRREQVANFRVEPPGLFRGRGKHPLMGKLKARVQPEGITINIGETAEVP-VPPAGHKWG 228
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H+ VTWLA W+DS+ G KYV L+A S+ KG SD KFEKAR+LK + IR Y
Sbjct: 229 AVQHDHTVTWLAMWRDSVVGNAKYVMLAASSSVKGQSDMMKFEKARKLKDKVDDIRASYM 288
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + + V QR+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 289 EDFKSNDVHVAQRAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHI 337
[30][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 210 bits (534), Expect = 6e-53
Identities = 100/173 (57%), Positives = 131/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RIQP D+T+N+G +APIPECP+PG
Sbjct: 468 AIVDGVKEKVGNFRVEPPALFRGRGEHPKMGKLKKRIQPSDITINIGKDAPIPECPIPGE 527
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+LK I +IR
Sbjct: 528 SWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIR 587
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y+K +K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+V ++
Sbjct: 588 AAYQKDLRSKDITKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANV 640
[31][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 210 bits (534), Expect = 6e-53
Identities = 101/169 (59%), Positives = 125/169 (73%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 411 DGRKQKVGNFRVEPPALFRGRGEHPKTGRVKTRVQPEQITINIGKGAAVPPPPA-GHKWK 469
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I IRK+YR
Sbjct: 470 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDFKKFEKARELKKHIDRIRKDYR 529
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 530 KGLKDELMANRQRATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 578
[32][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 210 bits (534), Expect = 6e-53
Identities = 99/169 (58%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G +A +P P PGH W
Sbjct: 417 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKDAKVPP-PPPGHKWK 475
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 476 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRKDYK 535
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 536 KSLKHELMSERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 584
[33][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 210 bits (534), Expect = 6e-53
Identities = 99/169 (58%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TGKVK R+ PE +T+N+G +A +P P GH W
Sbjct: 366 DGRKQKVGNFRVEPPSLFRGRGEHPKTGKVKTRVMPEQITINIGKDAKVPP-PPEGHKWK 424
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W++++ G YKYV L+A S KG SD+ KFEKAR+LK I IR++YR
Sbjct: 425 EVRHDQEGTWLAMWQENVNGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDKIREDYR 484
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQR+TA+YLIDK ALR GNEK EDEADTVGCCSL+ E++
Sbjct: 485 KGLKSDLMADRQRATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENI 533
[34][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 209 bits (532), Expect = 1e-52
Identities = 105/176 (59%), Positives = 127/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
FT DGR+E VGNFRVEPP+LF GRG+HP TGKVK+R+QPE +T+N+G A IPE P
Sbjct: 403 FTHCTWDGRKEKVGNFRVEPPSLFRGRGEHPKTGKVKQRVQPEQITINIGKGAKIPE-PP 461
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W + H+ TWLA W+++I YKYV L A SA KG SD KFEKAR+LK I
Sbjct: 462 KGHQWKAVQHDQKATWLAMWQENINQNYKYVMLGADSAIKGQSDFKKFEKARELKKHIDK 521
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y K ++ RQR+TA+Y IDKLALR GNEK E+EADTVGCCSL+ EH+
Sbjct: 522 IRKDYTKELKSEIMADRQRATAMYFIDKLALRAGNEKDTENEADTVGCCSLKYEHV 577
[35][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 209 bits (532), Expect = 1e-52
Identities = 99/173 (57%), Positives = 129/173 (74%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI P D+T+N+G AP+PECP+PG
Sbjct: 482 AVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRILPSDITINIGKGAPVPECPIPGE 541
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EK+R+LK I IR
Sbjct: 542 SWKEVKHDNTVTWLAFWNDPINPKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGHIQRIR 601
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V+++
Sbjct: 602 ENYTKDFKNKDVTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNV 654
[36][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 209 bits (532), Expect = 1e-52
Identities = 100/173 (57%), Positives = 130/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+V+G +E VGNFRVEPP LF GRG+HP GK+K RI+P D+T+N+G +APIPECP+PG
Sbjct: 455 AIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGE 514
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+LK I +IR
Sbjct: 515 RWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIR 574
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K +A+K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V ++
Sbjct: 575 AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANV 627
[37][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 209 bits (532), Expect = 1e-52
Identities = 99/173 (57%), Positives = 129/173 (74%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+KRRI P D+T+N+G AP+PECP+PG
Sbjct: 152 AVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRILPSDITINIGKGAPVPECPIPGE 211
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EK+R+LK I IR
Sbjct: 212 SWKEVKHDNTVTWLAFWNDPINPKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGHIQRIR 271
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V+++
Sbjct: 272 ENYTKDFKNKDVTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNV 324
[38][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 209 bits (532), Expect = 1e-52
Identities = 101/173 (58%), Positives = 131/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+V+G +E VGNFRVEPP+LF GRG+HP GK+K+ I+P D+T+N+G +APIPECP+PG
Sbjct: 472 AIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGE 531
Query: 196 NWGKIIHNSCVTWLAGWKDSI-TGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W +I H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR LK I IR
Sbjct: 532 SWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIR 591
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K +A+K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 592 AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 644
[39][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 209 bits (532), Expect = 1e-52
Identities = 101/169 (59%), Positives = 125/169 (73%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 411 DGRKQKVGNFRVEPPALFRGRGEHPKTGRVKIRVQPEQITINIGKGAAVPPPPA-GHKWK 469
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I IRK+YR
Sbjct: 470 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDFKKFEKARELKKHIDRIRKDYR 529
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 530 KGLKDELMANRQRATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 578
[40][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 209 bits (532), Expect = 1e-52
Identities = 105/176 (59%), Positives = 127/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
FT DGR+E VGNFRVEPP+LF GRG+HP TGKVK+R+QPE +T+N+G A IPE P
Sbjct: 402 FTHCTWDGRKEKVGNFRVEPPSLFRGRGEHPKTGKVKQRVQPEQITINIGKGAKIPE-PP 460
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W + H+ TWLA W+++I YKYV L A SA KG SD KFEKAR+LK I
Sbjct: 461 KGHQWKAVQHDQKATWLAMWQENINQNYKYVMLGADSAIKGQSDFKKFEKARELKKHIDK 520
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y K ++ RQR+TA+Y IDKLALR GNEK E+EADTVGCCSL+ EH+
Sbjct: 521 IRKDYTKELKSEIMADRQRATAMYFIDKLALRAGNEKDTENEADTVGCCSLKYEHV 576
[41][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 209 bits (531), Expect = 1e-52
Identities = 100/173 (57%), Positives = 127/173 (73%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RI P D+T+N+G AP+PECP+PG
Sbjct: 461 AVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGE 520
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR LK I +IR
Sbjct: 521 RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIR 580
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 581 ATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 633
[42][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 209 bits (531), Expect = 1e-52
Identities = 100/173 (57%), Positives = 127/173 (73%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RI P D+T+N+G AP+PECP+PG
Sbjct: 367 AVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGE 426
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR LK I +IR
Sbjct: 427 RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIR 486
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 487 ATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 539
[43][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 209 bits (531), Expect = 1e-52
Identities = 99/169 (58%), Positives = 120/169 (71%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR E V NFRVEPP LF GRG HPL GK+K R+QPED+T+N+G A +P P GH W
Sbjct: 170 DGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVP-VPPAGHKWA 228
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H+ VTWLA W+DS+ G KYV L+ S+ KG SD KFEKAR+LK + IR Y
Sbjct: 229 AVQHDHTVTWLAMWRDSVAGNMKYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYM 288
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + + V QR+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 289 EDFKSNDLHVAQRAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHI 337
[44][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 209 bits (531), Expect = 1e-52
Identities = 99/169 (58%), Positives = 120/169 (71%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR E V NFRVEPP LF GRG HPL GK+K R+QPED+T+N+G A +P P GH W
Sbjct: 170 DGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVP-VPPAGHKWA 228
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H+ VTWLA W+DS+ G KYV L+ S+ KG SD KFEKAR+LK + IR Y
Sbjct: 229 AVQHDHTVTWLAMWRDSVAGNMKYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYM 288
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + + V QR+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 289 EDFKSNDLHVAQRAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHI 337
[45][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 209 bits (531), Expect = 1e-52
Identities = 102/176 (57%), Positives = 127/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+T +VD E VGNFRVEPPNLF GRGDHP GK+K+ I PEDVT+N +AP P CPV
Sbjct: 215 YTHVIVDELRERVGNFRVEPPNLFRGRGDHPKMGKLKQYILPEDVTVNCAADAPAPRCPV 274
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH + ++H+ VTWLA + D+I KYV+L+A S FKG SD K+EKAR+LK I
Sbjct: 275 PGHAYKDVVHDPAVTWLAWFTDTINNQVKYVFLNAASGFKGQSDWLKYEKARKLKKYIRG 334
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR +Y K + + ++ TA+YLID+LALRVGNEK E+EADTVGCCSLRVEH+
Sbjct: 335 IRDDYTKKMKSSDDDEKELGTAVYLIDRLALRVGNEKNTEEEADTVGCCSLRVEHM 390
[46][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 209 bits (531), Expect = 1e-52
Identities = 95/176 (53%), Positives = 127/176 (72%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++D ++ VGNF++EPP LF GRGDHP GK+K+R+ PE+VT+N+G +A +P+ P
Sbjct: 75 EYGFCMMDHHKQRVGNFKIEPPGLFRGRGDHPKQGKLKKRVMPEEVTINIGKDAKVPDPP 134
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W K+I + VTWLA W ++I G YKYV L+ S KG D K+E AR+LK C+
Sbjct: 135 A-GHKWKKVICDDTVTWLACWIENIQGSYKYVMLNPTSRLKGEKDWRKYETARKLKECVD 193
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR++YRK W +K +RQR ALY IDKLALR G+EK +D ADTVGCCSLRVEH+
Sbjct: 194 KIREDYRKDWKSKEMRLRQRGVALYFIDKLALRAGHEKDDDTADTVGCCSLRVEHI 249
[47][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 208 bits (530), Expect = 2e-52
Identities = 100/173 (57%), Positives = 126/173 (72%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRGDHP GK+K RI P D+ +N+G +A +PECP+PG
Sbjct: 211 AVVDGVKEKVGNFRVEPPGLFRGRGDHPKMGKLKTRILPHDIVINIGKDAAVPECPIPGQ 270
Query: 196 NWGKIIHNSCVTWLAGWKDSITG-GYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W +I H++ VTWLA WKD I +KYV+L+A S+ KG SD K+EKAR LK I IR
Sbjct: 271 RWKEIRHDNTVTWLAYWKDPINDKEFKYVFLAASSSLKGQSDMQKYEKARMLKDYIDDIR 330
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ Y +++ +Q + A YLID+LALR GNEK EDEADTVGCCSL+VEH+
Sbjct: 331 RTYTHDFSSSDPTKQQIAVATYLIDRLALRAGNEKDEDEADTVGCCSLKVEHV 383
[48][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 208 bits (530), Expect = 2e-52
Identities = 102/176 (57%), Positives = 127/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+T +VD E VGNFRVEPPNLF GRGDHP GK+K+ I PEDVT+N +AP P CPV
Sbjct: 215 YTHVIVDELRERVGNFRVEPPNLFRGRGDHPKMGKLKQYILPEDVTVNCAADAPAPRCPV 274
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH + ++H+ VTWLA + D+I KYV+L+A S FKG SD K+EKAR+LK I
Sbjct: 275 PGHAYKDVVHDPAVTWLAWFTDTINNQVKYVFLNAASGFKGQSDWLKYEKARKLKKYIRG 334
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR +Y K + + ++ TA+YLID+LALRVGNEK E+EADTVGCCSLRVEH+
Sbjct: 335 IRDDYTKKMKSTDDDEKELGTAVYLIDRLALRVGNEKNTEEEADTVGCCSLRVEHM 390
[49][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 208 bits (530), Expect = 2e-52
Identities = 99/169 (58%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+QPE +T+N+G A +P P GH W
Sbjct: 370 DGRKQKVGNFRVEPPGLFRGRGEHPKTGKVKTRVQPEQITINIGKEAKVPP-PPEGHKWK 428
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W++++ G YKYV L+A S KG SD+ KFEKAR+LK I IR++YR
Sbjct: 429 EVRHDQEGTWLAMWQENVNGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIREDYR 488
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
G ++ RQR+TA+YLIDK ALR GNEK EDEADTVGCCSL+ E++
Sbjct: 489 VGLKSELMADRQRATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENV 537
[50][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 208 bits (529), Expect = 2e-52
Identities = 98/169 (57%), Positives = 120/169 (71%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR E V NFRVEPP LF GRG HPL GK+K R+QPED+T+N+G A +P P GH W
Sbjct: 170 DGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVP-VPPAGHKWA 228
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H+ VTWLA W+D++ G KYV L+ S+ KG SD KFEKAR+LK + IR Y
Sbjct: 229 AVQHDHTVTWLAMWRDNVAGNMKYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYM 288
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + + V QR+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 289 EAFKSNDLHVAQRAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHI 337
[51][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 207 bits (528), Expect = 3e-52
Identities = 99/173 (57%), Positives = 130/173 (75%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+V+G +E VGNFRVEPP LF GRG+HP GK+K RI+P D+T+N+G +APIP+CP+PG
Sbjct: 438 AIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPKCPIPGE 497
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+LK I +IR
Sbjct: 498 RWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIR 557
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K +A+K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V ++
Sbjct: 558 TAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANV 610
[52][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 207 bits (528), Expect = 3e-52
Identities = 101/176 (57%), Positives = 127/176 (72%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ L++GR E VGNFR+EPP LF GRG HP TG+VK+RI PEDV+LNL +APIP P
Sbjct: 263 KYKYCLLNGRRERVGNFRIEPPGLFRGRGSHPKTGRVKKRIYPEDVSLNLSEDAPIPP-P 321
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W +I H++ V WLA W++++T KYV +A S+ KG SD KFEKAR+LK I
Sbjct: 322 PEGHQWKEIKHDNTVAWLATWRENVTNTVKYVLFAADSSLKGRSDFKKFEKARELKKYIH 381
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y+K +++K RQ + A YLID ALR G EKAEDEADTVGCCSLR EH+
Sbjct: 382 RIRKDYKKNFSSKVMLERQMAVATYLIDVFALRAGGEKAEDEADTVGCCSLRYEHV 437
[53][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 207 bits (527), Expect = 4e-52
Identities = 97/169 (57%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DG++E V NFRVEPP LF GRG HP+ GK+K+R++PED+T+N+ +PIP+ P GH W
Sbjct: 173 DGKKEQVANFRVEPPGLFRGRGQHPMMGKLKKRVEPEDITINIDEFSPIPK-PPEGHRWK 231
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+++H VTWLA W+DSI G +KYV L+ SA KG SD KFEKAR+LK+ + IR+ Y
Sbjct: 232 EVLHEHNVTWLAMWRDSILGSFKYVMLAPSSAIKGQSDMLKFEKARELKNHVDEIRRCYI 291
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + ++ QR+ A+Y IDKLALRVGNEK DEADTVGCCSLRVEH+
Sbjct: 292 EDFESRELMKAQRAVAMYFIDKLALRVGNEKGSDEADTVGCCSLRVEHI 340
[54][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 207 bits (527), Expect = 4e-52
Identities = 105/178 (58%), Positives = 131/178 (73%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP- 183
F ALVD +E VGNFR+EPP LF GRG+HP +G +KRRI PEDVTLN+ +AP+P+ P
Sbjct: 165 FVYALVDWIKEKVGNFRIEPPGLFKGRGEHPKSGMLKRRIFPEDVTLNIAEDAPVPKVPN 224
Query: 184 -VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GH W I H++ VTWLA ++DSI +KY++LSA S FKGMSD+ K+EKAR+LK I
Sbjct: 225 SMKGHAWKDIFHDNTVTWLAYYRDSINNQFKYIFLSASSGFKGMSDYNKYEKARKLKDHI 284
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
+IR +YRK + RQ TA YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 285 DAIRSDYRKKMTSGDITQRQLGTATYLIDFLALRVGGEKDTDEEADTVGCCSLRVEHI 342
[55][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 207 bits (527), Expect = 4e-52
Identities = 97/169 (57%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DG++E V NFRVEPP LF GRG HP+ GK+K+R++PED+T+N+ +PIP+ P GH W
Sbjct: 173 DGKKEQVANFRVEPPGLFRGRGQHPMMGKLKKRVEPEDITINIDEFSPIPK-PPEGHRWK 231
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+++H VTWLA W+DSI G +KYV L+ SA KG SD KFEKAR+LK+ + IR+ Y
Sbjct: 232 EVLHEHNVTWLAMWRDSILGSFKYVMLAPSSAIKGQSDMLKFEKARELKNHVDEIRRCYI 291
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + ++ QR+ A+Y IDKLALRVGNEK DEADTVGCCSLRVEH+
Sbjct: 292 EDFESRELMKAQRAVAMYFIDKLALRVGNEKGSDEADTVGCCSLRVEHI 340
[56][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 207 bits (527), Expect = 4e-52
Identities = 97/169 (57%), Positives = 128/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G +AP+P P GH W
Sbjct: 387 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKSRVQPEQITINIGKDAPVPP-PPEGHRWK 445
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 446 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIDKIRKDYK 505
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 506 KNMKNELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 554
[57][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 207 bits (527), Expect = 4e-52
Identities = 96/176 (54%), Positives = 129/176 (73%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ + DGR++ VGNFRVEPP LF GRG+HP TG++K+R+ PE +T+N+G NA +P P
Sbjct: 386 EYMFCMWDGRKQKVGNFRVEPPGLFRGRGEHPKTGRIKKRVAPEQITINIGENAKVPPPP 445
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I
Sbjct: 446 A-GHRWKEVKHDHEGTWLAMWQENINGAYKYVMLAANSDIKGQSDFKKFEKARELKKHID 504
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR++YR+ ++ RQR+TA+YLID+ ALR GNEK EDEADTVGCCSL+ +H+
Sbjct: 505 RIRQDYRRELKSEKMVDRQRATAIYLIDQFALRAGNEKGEDEADTVGCCSLKFQHI 560
[58][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 207 bits (527), Expect = 4e-52
Identities = 97/176 (55%), Positives = 131/176 (74%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F L DGR+E +GNFRVEPP+LF GRGDHP TG++K+++ PE +T+N+G +A IP+ P
Sbjct: 388 FKYCLWDGRKEKMGNFRVEPPSLFRGRGDHPKTGRIKKQVFPEQITINIGKDAKIPK-PP 446
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++H++ TWLA W+++I G YKYV + S+ KG SDH KFEKAR+LK I
Sbjct: 447 DGHKWKAVVHDNKATWLASWQENINGAYKYVMTGSSSSVKGKSDHMKFEKARELKKHIDR 506
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y K ++ RQR+TA+YLID+ ALR GNEK AE+EA+TVGCCSL+ EH+
Sbjct: 507 IRRDYGKDLKSETMADRQRATAMYLIDRFALRAGNEKNAEEEAETVGCCSLKFEHV 562
[59][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 207 bits (527), Expect = 4e-52
Identities = 97/169 (57%), Positives = 128/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G +AP+P P GH W
Sbjct: 387 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKSRVQPEQITINIGKDAPVPP-PPEGHRWK 445
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 446 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIDKIRKDYK 505
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 506 KNMKNELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 554
[60][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 207 bits (527), Expect = 4e-52
Identities = 100/175 (57%), Positives = 128/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F L++GR+E VGNFR+EPP LF GRG HP TGK+KRR++PE VTLNL IPE P
Sbjct: 351 FKTCLLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVRPEQVTLNLSKGVKIPEPPA 410
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH+W ++ H++ VTWLA WK++I+ +KYV +A S+ KG SD KFEKAR+L+ + +
Sbjct: 411 -GHHWAEVRHDNEVTWLAMWKENISDSFKYVRFAANSSVKGQSDFKKFEKARELRQHVDA 469
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK EDEADTVGCCSLR EHL
Sbjct: 470 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHL 524
[61][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 207 bits (526), Expect = 5e-52
Identities = 105/178 (58%), Positives = 131/178 (73%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP- 183
F ALVD +E VGNFR+EPP LF GRG+HP +G +KRRI PEDVTLN+ +AP+P+ P
Sbjct: 177 FVYALVDWIKEKVGNFRIEPPGLFKGRGEHPKSGMLKRRIFPEDVTLNIAEDAPVPKVPN 236
Query: 184 -VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GH W I H++ VTWLA ++DSI +KY++LSA S FKGMSD+ K+EKAR+LK I
Sbjct: 237 SMKGHAWKDIFHDNTVTWLAYYRDSINNQFKYIFLSASSGFKGMSDYNKYEKARKLKDHI 296
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
+IR +YRK + RQ TA YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 297 DAIRDDYRKKMTSGDITQRQLGTATYLIDFLALRVGGEKDTDEEADTVGCCSLRVEHI 354
[62][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 207 bits (526), Expect = 5e-52
Identities = 98/169 (57%), Positives = 124/169 (73%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P GH W
Sbjct: 406 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVPTPPA-GHKWK 464
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IR +Y+
Sbjct: 465 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRSDYK 524
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 525 KGLKQELMAERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 573
[63][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 207 bits (526), Expect = 5e-52
Identities = 98/169 (57%), Positives = 124/169 (73%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P GH W
Sbjct: 411 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVP-IPPAGHKWK 469
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IR +Y+
Sbjct: 470 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRSDYK 529
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 530 KGLKQELMAERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 578
[64][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 207 bits (526), Expect = 5e-52
Identities = 98/169 (57%), Positives = 124/169 (73%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P GH W
Sbjct: 411 DGRKQKVGNFRVEPPALFRGRGEHPKTGKVKTRVMPEQITINIGKEAKVP-IPPAGHKWK 469
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IR +Y+
Sbjct: 470 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRSDYK 529
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
KG + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+
Sbjct: 530 KGLKQELMAERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHV 578
[65][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 207 bits (526), Expect = 5e-52
Identities = 99/175 (56%), Positives = 128/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G AP+P P
Sbjct: 386 YMYCLWDGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKARVQPEQITINIGKGAPVPP-PP 444
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I
Sbjct: 445 EGHRWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDFKKFEKARELKKHIDR 504
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y+K + RQ++TA+YLID+ ALR GNEK EDEADTVGCCSL+ E++
Sbjct: 505 IRKDYQKSLKHELMVERQKATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYENV 559
[66][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 206 bits (525), Expect = 6e-52
Identities = 99/170 (58%), Positives = 126/170 (74%), Gaps = 1/170 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E +GNFRVEPP LF GRG+HP GK+K+RI P ++TLN+G APIPECP+ G
Sbjct: 89 AVVDGVKEKIGNFRVEPPGLFRGRGEHPKMGKLKKRIHPCEITLNIGKGAPIPECPIAGE 148
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L AGS+ KG+SD K+EKAR L I +IR
Sbjct: 149 RWKEVKHDNTVTWLAFWADPINPKEFKYVFLGAGSSLKGLSDKEKYEKARNLTDHIDNIR 208
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRV 522
Y K + AK ++RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V
Sbjct: 209 TTYTKNFTAKDVKMRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 258
[67][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 206 bits (525), Expect = 6e-52
Identities = 98/175 (56%), Positives = 130/175 (74%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G +AP+P P
Sbjct: 498 YMYCLWDGRKQKVGNFRVEPPALFRGRGEHPKTGRVKARVQPEQITINIGKDAPVPP-PP 556
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H+ TWLA W+++I G YKYV L+A S KG+SD+ KFEKAR+LK I
Sbjct: 557 EGHRWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGLSDYKKFEKARELKKHIDR 616
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y+K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 617 IRKDYQKALKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 671
[68][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 206 bits (525), Expect = 6e-52
Identities = 98/175 (56%), Positives = 130/175 (74%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G +AP+P P
Sbjct: 386 YMYCLWDGRKQKVGNFRVEPPALFRGRGEHPKTGRVKARVQPEQITINIGKDAPVPP-PP 444
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H+ TWLA W+++I G YKYV L+A S KG+SD+ KFEKAR+LK I
Sbjct: 445 EGHRWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGLSDYKKFEKARELKKHIDR 504
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y+K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 505 IRKDYQKALKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 559
[69][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 206 bits (525), Expect = 6e-52
Identities = 99/170 (58%), Positives = 126/170 (74%), Gaps = 1/170 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E +GNFRVEPP LF GRG+HP GK+K+RI P ++TLN+G APIPECP+ G
Sbjct: 491 AVVDGVKEKIGNFRVEPPGLFRGRGEHPKMGKLKKRIHPCEITLNIGKGAPIPECPIAGE 550
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L AGS+ KG+SD K+EKAR L I +IR
Sbjct: 551 RWKEVKHDNTVTWLAFWADPINPKEFKYVFLGAGSSLKGLSDKEKYEKARNLTDHIDNIR 610
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRV 522
Y K + AK ++RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V
Sbjct: 611 TTYTKNFTAKDVKMRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 660
[70][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 205 bits (522), Expect = 1e-51
Identities = 94/177 (53%), Positives = 125/177 (70%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNF++EPP LF GRG+HP GK+K+R+ PED+ +N ++ IP+
Sbjct: 562 KEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPK- 620
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W +I H+ VTWLA W ++I G KYV L+ S KG D K+E AR+L I
Sbjct: 621 PPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLI 680
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR EYR+ W +K +RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 681 DKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 737
[71][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 205 bits (522), Expect = 1e-51
Identities = 101/175 (57%), Positives = 123/175 (70%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F +DGR+E VGNFR+EPP LF GRG HP TGK+KRR+ PEDV LNL A IP+ P
Sbjct: 257 FKFCFLDGRKEQVGNFRIEPPGLFRGRGAHPKTGKLKRRVYPEDVVLNLDKEAEIPKAP- 315
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H+S V WLA W+++I+ +KYV +A S+ KGMSD KFEKARQL+ I +
Sbjct: 316 EGHKWGEIRHDSTVQWLAMWRENISNSFKYVRFAANSSLKGMSDFKKFEKARQLRGFIDA 375
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y K +K RQ + A Y ID ALR G EKA+DEADTVGCCSLR EH+
Sbjct: 376 IRADYTKNLKSKVMLERQIAVACYFIDVFALRAGGEKADDEADTVGCCSLRYEHV 430
[72][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 205 bits (522), Expect = 1e-51
Identities = 101/175 (57%), Positives = 125/175 (71%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L++GR E VGNF+VEPP+LF GRG HP TGK+K+R+ PED+TLNLG APIP P
Sbjct: 266 YRTCLLNGRRENVGNFKVEPPSLFRGRGAHPKTGKLKKRVYPEDITLNLGIEAPIPPAP- 324
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H+ V WLA WK++I+ +KYV L+A S+ KG+SD KFE AR+LK I
Sbjct: 325 EGHKWGEIRHDKSVVWLAMWKENISDSFKYVKLAANSSIKGISDMKKFETARRLKDHIER 384
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y+K + RQ +TA YLID ALR G EK EDEADTVGCCSLR EH+
Sbjct: 385 IRDDYKKMLKDPFMQNRQIATATYLIDVFALRAGGEKGEDEADTVGCCSLRYEHV 439
[73][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6H1W4_PENCW
Length = 864
Score = 205 bits (522), Expect = 1e-51
Identities = 97/169 (57%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G +A +P P PGH W
Sbjct: 369 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKTRVQPEQITINIGKDAKVPP-PPPGHKWK 427
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD KFEKAR+LK I IRK+Y+
Sbjct: 428 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDFKKFEKARELKKHIEKIRKDYQ 487
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 488 KNLKHDMMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 536
[74][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 205 bits (522), Expect = 1e-51
Identities = 97/169 (57%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G +AP+P P GH W
Sbjct: 390 DGRKQKVGNFRVEPPALFRGRGEHPKTGRVKSRVQPEQITINIGKDAPVPP-PPEGHKWK 448
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 449 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKHHIGRIRKDYQ 508
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 509 KNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 557
[75][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 205 bits (521), Expect = 2e-51
Identities = 101/176 (57%), Positives = 126/176 (71%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
FT + DGR++ VGNFRVEPP+LF GRG+HP TGKVK R+ PE +T+N+G A IP+ P
Sbjct: 412 FTHCMWDGRKQKVGNFRVEPPSLFRGRGEHPKTGKVKNRVTPEQITINIGKGAKIPD-PP 470
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W + H+ TWLA W+++I YKYV L A S KG SD KFEKAR+LK I
Sbjct: 471 KGHQWKAVQHDQKATWLAMWQENINNNYKYVMLGAASDIKGQSDFKKFEKARELKKHIDR 530
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y K ++ RQR+TA+YLID+LALR GNEK E+EADTVGCCSL+ EH+
Sbjct: 531 IRKDYTKELKSEVMADRQRATAMYLIDRLALRAGNEKDTENEADTVGCCSLKYEHI 586
[76][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 204 bits (520), Expect = 2e-51
Identities = 97/169 (57%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 377 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP-PPEGHKWK 435
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK IA IRK+Y+
Sbjct: 436 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIARIRKDYQ 495
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 496 KNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 544
[77][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 204 bits (520), Expect = 2e-51
Identities = 97/169 (57%), Positives = 127/169 (75%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 377 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP-PPEGHKWK 435
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK IA IRK+Y+
Sbjct: 436 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIARIRKDYQ 495
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 496 KNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 544
[78][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 204 bits (520), Expect = 2e-51
Identities = 101/176 (57%), Positives = 128/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ + DGR+E VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G A +P P
Sbjct: 407 YKTCIWDGRKEDVGNFRVEPPGLFRGRGEHPKTGKVKLRVTPEQITINIGKEATVPS-PP 465
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W I H++ TWLA W+++I G YKYV L+A S+ KG SD+ KFEKAR+LK I
Sbjct: 466 EGHKWKAIQHDNKATWLAMWQENINGAYKYVMLAAKSSIKGQSDYKKFEKARELKEHIDR 525
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y + A+ RQR+TA+YLIDK ALR GNEK AE+EA+TVGCCSL+ EH+
Sbjct: 526 IRKDYTQDLHAELMADRQRATAVYLIDKFALRAGNEKDAENEAETVGCCSLKYEHV 581
[79][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 204 bits (519), Expect = 3e-51
Identities = 98/170 (57%), Positives = 125/170 (73%), Gaps = 1/170 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A++DG E +GNFRVEPP LF GRG+HP GK+K+RI+P D+T+N+G APIPECP+PG
Sbjct: 489 AVLDGVRERIGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKEAPIPECPIPGE 548
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ H++ VTWLA W D I +KYV+L+A S+ KG SD K+EKAR+L + I SIR
Sbjct: 549 RWKEVKHDNTVTWLAFWSDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLHNHIGSIR 608
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRV 522
Y K + K RQ + A YLIDKLALR GNEK +DEADTVGCC+L+V
Sbjct: 609 AAYTKDFNNKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 658
[80][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 204 bits (519), Expect = 3e-51
Identities = 99/169 (58%), Positives = 120/169 (71%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR E V NFRVEPP LF GRG HPL GK+K R+QPED+T+N+G A +P P GH W
Sbjct: 485 DGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVP-VPPAGHKWA 543
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H+ VTWLA W+DS+ G KYV L+ S+ KG SD KFEKAR+LK + IR Y
Sbjct: 544 AVQHDHTVTWLAMWRDSVAGNMKYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYM 603
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + + V QR+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 604 EDFKSNDLHVAQRAVAMY-IDRLALRVGNEKGEDEADTVGCCSLRVEHI 651
[81][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 204 bits (519), Expect = 3e-51
Identities = 94/177 (53%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G ++ +P
Sbjct: 168 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPS- 226
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 227 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 286
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 287 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 343
[82][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 204 bits (519), Expect = 3e-51
Identities = 94/177 (53%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G ++ +P
Sbjct: 561 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPS- 619
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 620 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 679
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 680 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 736
[83][TOP]
>UniRef100_Q1WWG8 IP16129p (Fragment) n=1 Tax=Drosophila melanogaster
RepID=Q1WWG8_DROME
Length = 382
Score = 204 bits (519), Expect = 3e-51
Identities = 94/177 (53%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G ++ +P
Sbjct: 74 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPS- 132
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 133 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 192
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 193 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 249
[84][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 204 bits (519), Expect = 3e-51
Identities = 94/177 (53%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G ++ +P
Sbjct: 168 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPS- 226
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 227 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 286
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 287 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 343
[85][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 204 bits (519), Expect = 3e-51
Identities = 93/177 (52%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G N+ +P+
Sbjct: 616 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIAARDVSINCGKNSKVPQ- 674
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 675 PPPGERWKEVRHDNTVTWLASWTENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKFI 734
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 735 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 791
[86][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 204 bits (519), Expect = 3e-51
Identities = 100/173 (57%), Positives = 127/173 (73%)
Frame = +1
Query: 13 VALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPG 192
V L+ GR+E V F+++PP+LF GRG HP TGK+KRR+QPEDV LNL +APIPE P G
Sbjct: 235 VLLLTGRKEQVDTFKIDPPDLFRGRGAHPKTGKLKRRVQPEDVVLNLDKDAPIPEPPA-G 293
Query: 193 HNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
H WG+I H++ V WL W+++I+ +KYV L+A S+ KGMSD KFEK+R+LK+ I IR
Sbjct: 294 HKWGEIRHDNTVQWLCMWRENISNSFKYVRLAANSSLKGMSDFKKFEKSRELKNYIDIIR 353
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+YRK +K RQ + A YLID ALR G EK+EDEADTVGCCSLR EH+
Sbjct: 354 ADYRKNLKSKVMLDRQIAVATYLIDVFALRAGGEKSEDEADTVGCCSLRYEHI 406
[87][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 204 bits (519), Expect = 3e-51
Identities = 101/176 (57%), Positives = 128/176 (72%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ + DGR+E VGNFRVEPP LF GRG+HP TGKVK R+ PE +T+N+G +A +P P
Sbjct: 408 YKTCIWDGRKEDVGNFRVEPPGLFRGRGEHPKTGKVKLRVTPEQITINIGKDATVPS-PP 466
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W I H++ TWLA W+++I G YKYV L+A S+ KG SD KFEKAR+LK I
Sbjct: 467 EGHKWKAIQHDNKATWLAMWQENINGAYKYVMLAAKSSIKGQSDFKKFEKARELKEHIDR 526
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y + A+ RQR+TA+YLIDK ALR GNEK AE+EA+TVGCCSL+ EH+
Sbjct: 527 IRKDYTQDLKAELMADRQRATAVYLIDKFALRAGNEKDAENEAETVGCCSLKYEHV 582
[88][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 204 bits (519), Expect = 3e-51
Identities = 94/177 (53%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G ++ +P
Sbjct: 559 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPS- 617
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 618 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 677
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 678 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 734
[89][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 204 bits (518), Expect = 4e-51
Identities = 94/177 (53%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G + +P
Sbjct: 167 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKESKVPS- 225
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 226 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 285
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 286 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 342
[90][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 204 bits (518), Expect = 4e-51
Identities = 94/177 (53%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G + +P
Sbjct: 556 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKESKVPS- 614
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 615 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 674
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 675 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 731
[91][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 204 bits (518), Expect = 4e-51
Identities = 96/169 (56%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP+LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 378 DGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP-PPEGHKWK 436
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK I IRK+Y+
Sbjct: 437 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKYIGKIRKDYQ 496
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 497 KNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 545
[92][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 204 bits (518), Expect = 4e-51
Identities = 98/175 (56%), Positives = 129/175 (73%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L +G +E VGNFRVEPP LF GRG HP TGK+KRR+ PE VTLN+G A IPE P
Sbjct: 280 YKTCLFNGHKELVGNFRVEPPGLFRGRGAHPRTGKLKRRVYPEMVTLNIGAGAKIPEAP- 338
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH+WG+I +++ VTWLA W+++I +KYV +A S+ KG+SD KFE AR+L+S + +
Sbjct: 339 PGHSWGEIKNDNTVTWLAMWRENIADSFKYVRFAASSSIKGVSDFKKFETARRLRSHVDA 398
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ ++A+YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 399 IRKDYTKMLKSELMQDRQMASAIYLIDVFALRAGGEKGDDEADTVGCCSLRYEHI 453
[93][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 203 bits (517), Expect = 5e-51
Identities = 97/169 (57%), Positives = 126/169 (74%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR++ VGNFRVEPP LF GRG+HP TG+VK R+QPE +T+N+G A +P P GH W
Sbjct: 377 DGRKQKVGNFRVEPPPLFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP-PPEGHKWK 435
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H+ TWLA W+++I G YKYV L+A S KG SD+ KFEKAR+LK IA IRK+Y+
Sbjct: 436 EVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIARIRKDYQ 495
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + RQ++TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++
Sbjct: 496 KNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENV 544
[94][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 203 bits (516), Expect = 7e-51
Identities = 97/169 (57%), Positives = 123/169 (72%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
+G++E V NFRVEPP LF GRG+HP+ GK+K+RI PEDV LN+G APIP+ P GH W
Sbjct: 198 NGKKEQVANFRVEPPGLFRGRGEHPMRGKLKKRILPEDVVLNIGKEAPIPQAPA-GHKWK 256
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++H+ VTWLA W + G KYV L+ S KG SD+AKFE AR+LK+ I IR+ Y
Sbjct: 257 GVVHDQNVTWLAMWYEPTIGQCKYVMLAPSSTLKGQSDYAKFETARELKNHIDDIRESYT 316
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K +++ + RQR+ A Y IDKLALRVG+EK E+EADTVGCCSLR EH+
Sbjct: 317 KDFSSTDEMERQRAVATYFIDKLALRVGHEKGEEEADTVGCCSLRKEHI 365
[95][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 203 bits (516), Expect = 7e-51
Identities = 97/169 (57%), Positives = 123/169 (72%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
+G++E V NFRVEPP LF GRG+HP+ GK+K+RI PEDV LN+G APIP+ P GH W
Sbjct: 233 NGKKEQVANFRVEPPGLFRGRGEHPMRGKLKKRILPEDVVLNIGKEAPIPQAPA-GHKWK 291
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++H+ VTWLA W + G KYV L+ S KG SD+AKFE AR+LK+ I IR+ Y
Sbjct: 292 GVVHDQNVTWLAMWYEPTIGQCKYVMLAPSSTLKGQSDYAKFETARELKNHIDDIRESYT 351
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K +++ + RQR+ A Y IDKLALRVG+EK E+EADTVGCCSLR EH+
Sbjct: 352 KDFSSTDEMERQRAVATYFIDKLALRVGHEKGEEEADTVGCCSLRKEHI 400
[96][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 203 bits (516), Expect = 7e-51
Identities = 100/175 (57%), Positives = 126/175 (72%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ PE VTLNLG +A IPE P
Sbjct: 282 YRTCYLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVVPEQVTLNLGKDAKIPEPPA 341
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ VTWLA WK++I+ KYV + S+ KG SD KFE AR+L+ + S
Sbjct: 342 -GHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVKGQSDFKKFETARKLRDHVDS 400
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK EDEADTVGCCSLR EH+
Sbjct: 401 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHV 455
[97][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 203 bits (516), Expect = 7e-51
Identities = 100/175 (57%), Positives = 126/175 (72%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ PE VTLNLG +A IPE P
Sbjct: 282 YRTCYLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVVPEQVTLNLGKDAKIPEPPA 341
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ VTWLA WK++I+ KYV + S+ KG SD KFE AR+L+ + S
Sbjct: 342 -GHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVKGQSDFKKFETARKLRDHVDS 400
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK EDEADTVGCCSLR EH+
Sbjct: 401 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHV 455
[98][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 202 bits (515), Expect = 9e-51
Identities = 93/177 (52%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRIQ DV++N G + +P
Sbjct: 577 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKESHVPS- 635
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 636 PPPGQRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 695
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 696 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 752
[99][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 202 bits (515), Expect = 9e-51
Identities = 98/177 (55%), Positives = 129/177 (72%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ AL+DGR+ T+GNFR+EPP LF GRG+HP GK+K R+ PEDV +N+GP +PE P
Sbjct: 1989 EYGFALMDGRKVTIGNFRIEPPGLFQGRGEHPKMGKLKLRVMPEDVIINVGPKDKVPEPP 2048
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWLAGWK++I KY+ LSA + KG +D K+E AR+LK +
Sbjct: 2049 A-GHKWKEVKHDNTVTWLAGWKENIQDQNKYIMLSADTHIKGRNDWKKYETARKLKEHVD 2107
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y + +K RQR+TALY IDKLALR G EK AE++ADTVGCCSLRVEHL
Sbjct: 2108 KIRRDYTRDLKSKLMFERQRATALYFIDKLALRAGGEKDAEEQADTVGCCSLRVEHL 2164
[100][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 202 bits (514), Expect = 1e-50
Identities = 90/177 (50%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +DG +E +GNF++EPP LF GRG+HP G +KRR++ ED+ +N ++ IPE
Sbjct: 509 KEYGFCNIDGHKEKIGNFKIEPPGLFRGRGEHPKMGMLKRRVEAEDIIINCSQDSKIPE- 567
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H+ VTWLA W +++ KY+ L+ S KG D K+E AR+L CI
Sbjct: 568 PPPGHKWKEVRHDDNVTWLASWTENVQNQVKYIMLNPSSKLKGEKDWQKYETARRLHKCI 627
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR+EY+ W +K +RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 628 DKIREEYKDDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 684
[101][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 202 bits (514), Expect = 1e-50
Identities = 93/177 (52%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G ++ +P
Sbjct: 557 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIHASDVSINCGKDSKVPS- 615
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 616 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 675
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 676 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 732
[102][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 201 bits (512), Expect = 2e-50
Identities = 98/178 (55%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ DG +E +GNFRVEPP+LF GRG+HP G++K+RI PEDV +N ++ P
Sbjct: 11 KEYGFCSFDGHKEKIGNFRVEPPSLFRGRGEHPKQGQLKKRIGPEDVIINCSKDSKWP-I 69
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W K+IH + VTWLA W ++I G KYV L+ S KG D AK+E AR+LK +
Sbjct: 70 PPEGHKWKKVIHENSVTWLASWTENIQGAIKYVMLNPSSRIKGEKDWAKYETARKLKESV 129
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR EYR+ W +K VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 130 DRIRNEYREDWKSKEMRVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 187
[103][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 201 bits (512), Expect = 2e-50
Identities = 92/176 (52%), Positives = 123/176 (69%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F L+DG E +GNF++EPP LF GRG+HP G++K+RIQPEDV +N ++ IPE P
Sbjct: 173 EFGYCLLDGHREKIGNFKLEPPGLFRGRGEHPKMGRLKKRIQPEDVAINCSKDSKIPEPP 232
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWLA W ++I KY+ L+ S KG D K+E AR+LK C+
Sbjct: 233 A-GHKWKRVQHDNTVTWLASWLENIPKRPKYIMLNPSSKLKGEKDWQKYETARRLKECVK 291
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
SIRK Y + W ++ + RQR A+Y IDKLALR GNEK ++ ADTVGCCSLRVEH+
Sbjct: 292 SIRKRYMQDWKSREMKSRQRGVAIYFIDKLALRAGNEKDDESADTVGCCSLRVEHI 347
[104][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 201 bits (512), Expect = 2e-50
Identities = 92/177 (51%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G + +P+
Sbjct: 618 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIAAADVSINCGKQSKVPQ- 676
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 677 PPPGERWKEVRHDNTVTWLASWTENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKFI 736
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 737 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 793
[105][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 201 bits (512), Expect = 2e-50
Identities = 99/175 (56%), Positives = 125/175 (71%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F ++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ PE VTLNL +A IPE P
Sbjct: 279 FKTCYLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVAPEQVTLNLSKDAKIPEPPA 338
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ VTWLA WK++I+ KYV + S+ KG SD KFE AR+L++ +
Sbjct: 339 -GHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVKGQSDFKKFETARKLRNYVDD 397
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK EDEADTVGCCSLR EH+
Sbjct: 398 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHV 452
[106][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 201 bits (511), Expect = 3e-50
Identities = 92/177 (51%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ + +DG +E +GNF++EPP LF GRG+HP GK+K+R+ PEDV +N ++ P+
Sbjct: 592 KEYGICTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRLVPEDVLINCSKDSVHPK- 650
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W +I H+ VTWLA W ++I G KYV L+ S KG D K+E AR+L +
Sbjct: 651 PPPGHKWKEIRHDPTVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAKSV 710
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR+ W +K +RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 711 DKIRATYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 767
[107][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 201 bits (511), Expect = 3e-50
Identities = 92/177 (51%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI +V++N G N+ +P
Sbjct: 570 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIGASEVSINCGKNSKVPT- 628
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 629 PPPGQRWKEVRHDNTVTWLASWVENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 688
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 689 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 745
[108][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 201 bits (510), Expect = 4e-50
Identities = 99/174 (56%), Positives = 127/174 (72%), Gaps = 2/174 (1%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RI+P D+T+N+G +APIPECP+PG
Sbjct: 504 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGE 563
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ +++ VTWLA W D I +KYV+L+A S KG SD K+EKAR LK I IR
Sbjct: 564 RWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIR 623
Query: 373 KEYRKGWA-AKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 624 AAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 677
[109][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 201 bits (510), Expect = 4e-50
Identities = 97/175 (55%), Positives = 126/175 (72%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ PE VTLNLG +A +PE P
Sbjct: 279 YKTCYLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVAPEQVTLNLGKDAKVPEPPA 338
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ VTWLA WK++I+ KYV + S+ KG SD KFE AR+L++ +
Sbjct: 339 -GHQWGEIRHDNEVTWLAMWKENISDSTKYVRFANNSSIKGQSDFKKFETARRLRNHVDE 397
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 398 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGDDEADTVGCCSLRYEHV 452
[110][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 200 bits (509), Expect = 5e-50
Identities = 92/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NFR+EPP LF GRG+HP G +KRRIQPED+ +N ++ +P
Sbjct: 352 KEYGFCVMDNHRERIANFRIEPPGLFRGRGNHPKMGMLKRRIQPEDIIINCSKDSKVPP- 410
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 411 PPPGHRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 470
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 471 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 528
[111][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 200 bits (509), Expect = 5e-50
Identities = 94/177 (53%), Positives = 127/177 (71%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F ALVDG E VGN+ +EPP F GRG+HP GK+K+R++PE V +N+ +AP+P C
Sbjct: 73 KFGYALVDGHLEKVGNYNMEPPGAFRGRGEHPKMGKLKQRVEPEQVMINVSEDAPVPMCS 132
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
VPGH WG++ H+ V WL WK++I KY+ L+A S+FKG SD +K+ KA +L I
Sbjct: 133 VPGHAWGEVRHDPTVQWLCQWKENINNQVKYMQLAAQSSFKGKSDRSKYNKAAKLCGNID 192
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR +Y+K +K E RQ +TA+++ID+LALRVG EK ++EADTVGCCSLRVEHL
Sbjct: 193 KIRTDYKKNLTSKSLETRQLATAMWVIDRLALRVGGEKDTDEEADTVGCCSLRVEHL 249
[112][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 200 bits (508), Expect = 6e-50
Identities = 91/177 (51%), Positives = 123/177 (69%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +DG +E +GNFR+EPP LF GRG+HP G +K+R+ PEDV +N ++ IP+
Sbjct: 540 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVLPEDVIINCSKDSKIPK- 598
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W K+ H+ VTWLA W +++ G KYV L+ S KG D K+E AR+L I
Sbjct: 599 PPDGHKWKKVQHDPSVTWLASWTENVQGNVKYVMLNPSSKLKGEKDMVKYETARKLAKKI 658
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR++Y+ W +K ++RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 659 DKIREQYQADWKSKEMKIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 715
[113][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 200 bits (508), Expect = 6e-50
Identities = 95/177 (53%), Positives = 126/177 (71%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++T A+VDG + VGNFRVEPP LF GRG+HP G++K+RI P D+ +N+G A +PECP
Sbjct: 461 KYTWAIVDGVKRRVGNFRVEPPGLFRGRGEHPKMGRLKKRIHPSDIVINIGSEAQVPECP 520
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGG-YKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+PG W I +++ VTWL W D I +KYV+L+A S+ KG SD K+EKAR LK I
Sbjct: 521 IPGEGWKDIRNDNTVTWLCYWSDPINPKLFKYVFLAASSSLKGQSDKEKYEKARMLKDYI 580
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+IR Y K + +K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 581 GNIRAYYTKDFTSKDITKQQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 637
[114][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 200 bits (508), Expect = 6e-50
Identities = 99/174 (56%), Positives = 126/174 (72%), Gaps = 2/174 (1%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RI+P D+T+N+G +APIPECP+PG
Sbjct: 503 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGE 562
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ +++ VTWLA W D I KYV+L+A S KG SD K+EKAR LK I IR
Sbjct: 563 RWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIR 622
Query: 373 KEYRKGWA-AKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 623 AAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 676
[115][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 200 bits (508), Expect = 6e-50
Identities = 98/174 (56%), Positives = 126/174 (72%), Gaps = 2/174 (1%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GRG+HP GK+K+RI+P D+T+N+G +APIPECP+PG
Sbjct: 503 AIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGE 562
Query: 196 NWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W ++ +++ VTWLA W D + KYV+L+A S KG SD K+EKAR LK I IR
Sbjct: 563 RWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIR 622
Query: 373 KEYRKGWA-AKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
Y K + K +Q + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 623 AAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 676
[116][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 200 bits (508), Expect = 6e-50
Identities = 99/175 (56%), Positives = 125/175 (71%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ++GR+E VGNFR+EPP LF GRG HP TGK+KRR+ E VTLNLG +A IPE P
Sbjct: 280 YRTCYLNGRKELVGNFRIEPPGLFRGRGAHPKTGKLKRRVVSEQVTLNLGKDAKIPEPPA 339
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG+I H++ VTWLA WK++I+ KYV + S+ KG SD KFE AR+L+ + S
Sbjct: 340 -GHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVKGQSDFKKFETARKLRDHVDS 398
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K ++ + RQ +TA+YLID ALR G EK EDEADTVGCCSLR EH+
Sbjct: 399 IRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHV 453
[117][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 199 bits (507), Expect = 8e-50
Identities = 93/178 (52%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ L+D E +GNFR+EPP LF GRGDHP GK+KRRI+PED+ +N ++ P+
Sbjct: 319 QEYGFCLMDNHRERIGNFRIEPPGLFRGRGDHPKMGKLKRRIRPEDIIINCSKDSVQPKA 378
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 379 P-PGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 437
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 438 ERIRAQYREDWRSKEMRIRQRAVALYFIDKLALRAGNEKDEGETADTVGCCSLRVEHI 495
[118][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 199 bits (507), Expect = 8e-50
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 338 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[119][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 199 bits (507), Expect = 8e-50
Identities = 100/189 (52%), Positives = 129/189 (68%), Gaps = 17/189 (8%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A+VDG +E VGNFRVEPP LF GR P GK+K+RI P D+T+N+G +APIPECP+PG
Sbjct: 471 AVVDGVKENVGNFRVEPPGLFRGRESIPKMGKLKKRISPSDITINIGKDAPIPECPIPGE 530
Query: 196 NWGKIIHNSCVTWLAGWKDSITG-GYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
+W ++ H++ VTWLA W D I G +KYV+L+A S+ KG SD K+EKAR+LK I IR
Sbjct: 531 SWKEVRHDNTVTWLAYWNDPINGKEFKYVFLAASSSLKGQSDKEKYEKARKLKGYIEGIR 590
Query: 373 KEYRKGWAAKGKEVRQ----------------RSTALYLIDKLALRVGNEKAEDEADTVG 504
Y K +++K RQ + A YLIDKLALR GNEK +DEADTVG
Sbjct: 591 TAYTKDFSSKDVTKRQIAVATYLIDKLALRAGNAVATYLIDKLALRAGNEKDDDEADTVG 650
Query: 505 CCSLRVEHL 531
CC+L+VE++
Sbjct: 651 CCTLKVENV 659
[120][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 199 bits (507), Expect = 8e-50
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 131 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 189
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 190 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 249
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 250 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 307
[121][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 199 bits (507), Expect = 8e-50
Identities = 92/177 (51%), Positives = 121/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G + +P
Sbjct: 627 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIGASDVSINCGKESKVPP- 685
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 686 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKSI 745
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 746 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 802
[122][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 199 bits (507), Expect = 8e-50
Identities = 92/177 (51%), Positives = 121/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G + +P
Sbjct: 615 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIGASDVSINCGKESKVPP- 673
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 674 PPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKSI 733
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 734 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 790
[123][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 199 bits (507), Expect = 8e-50
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 394
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 395 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 454
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 455 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 512
[124][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 199 bits (507), Expect = 8e-50
Identities = 97/170 (57%), Positives = 118/170 (69%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DGR E VGNFR+EPP LF GRG HP GK+KRR+ PEDV LNL APIPE P GH W
Sbjct: 291 IDGRVEQVGNFRIEPPGLFRGRGAHPKNGKLKRRVYPEDVVLNLDKEAPIPE-PPKGHKW 349
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
G+I H++ V WL+ W+++I+ +KYV +A S KGMSD KFEKAR LK I +R +Y
Sbjct: 350 GEIRHDNTVQWLSMWRENISNSFKYVRFAANSTLKGMSDFKKFEKARMLKDHIDKVRTDY 409
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+ + RQ + A YLID ALR G EKA+DEADTVGCCSLR EH+
Sbjct: 410 KSKMKSPKTLDRQMAVATYLIDVFALRAGGEKADDEADTVGCCSLRYEHV 459
[125][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 199 bits (507), Expect = 8e-50
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 394
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 395 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 454
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 455 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 512
[126][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 199 bits (507), Expect = 8e-50
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 338 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[127][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 199 bits (506), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 320 KEYGFCIMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 378
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 379 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 438
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 439 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 496
[128][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 199 bits (506), Expect = 1e-49
Identities = 93/178 (52%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+QF ++D +E + NFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ PE
Sbjct: 322 QQFGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKYPE- 380
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 381 PPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 440
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 441 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 498
[129][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 199 bits (506), Expect = 1e-49
Identities = 93/178 (52%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+QF ++D +E + NFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ PE
Sbjct: 322 QQFGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKYPE- 380
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 381 PPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 440
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 441 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 498
[130][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 199 bits (506), Expect = 1e-49
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 336 KEYGFCVMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 394
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 395 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 454
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 455 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 512
[131][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 199 bits (506), Expect = 1e-49
Identities = 93/178 (52%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+QF ++D +E + NFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ PE
Sbjct: 327 QQFGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKYPE- 385
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 386 PPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 445
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 446 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 503
[132][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 199 bits (506), Expect = 1e-49
Identities = 98/175 (56%), Positives = 123/175 (70%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
F +DGR+E VGNF++EPP LF GRG HP TGK+KRR+ PEDV LNL +A IP P
Sbjct: 344 FKYCELDGRKEQVGNFKIEPPGLFRGRGAHPKTGKLKRRVYPEDVVLNLDKDATIPPLP- 402
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
G WG+I H++ V WLA W+++I+ +KYV +A S+ G SD KFEK+RQLK I +
Sbjct: 403 EGQKWGEIRHDNTVQWLAMWRENISNSFKYVRFAANSSLNGQSDFKKFEKSRQLKYHIDA 462
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K K RQ++ A+YLID ALR G EKA+DEADTVGCCSLR EH+
Sbjct: 463 IRKDYNKNLKNKVMLERQKAVAIYLIDVFALRAGGEKADDEADTVGCCSLRYEHV 517
[133][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 199 bits (505), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 336 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 394
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 395 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 454
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 455 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 512
[134][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 199 bits (505), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 329 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 387
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 388 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 447
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 448 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 505
[135][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 199 bits (505), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 340 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 398
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 399 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 458
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 459 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 516
[136][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 199 bits (505), Expect = 1e-49
Identities = 100/174 (57%), Positives = 124/174 (71%), Gaps = 2/174 (1%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
ALVDG E VGN+ +E P LF GRG+HP G +K RI PE++T+NL AP+P+C +PGH
Sbjct: 161 ALVDGCLERVGNYTLEQPTLFKGRGEHPKAGLLKARIFPEELTVNLSTQAPVPQCKLPGH 220
Query: 196 NWGKIIHNSCVTWLAGWKDSIT--GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASI 369
+WGKI+H + VTWL + DS +KYV +A S FK M+D K+EKAR+LK+ I I
Sbjct: 221 SWGKIVHRNDVTWLFSYVDSSIRKDNHKYVQFAATSRFKQMNDKRKYEKARRLKNQIDQI 280
Query: 370 RKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
R+ Y K + + RQ TA YLIDKLALRVGNEK EDEADTVGCCSLRVEH+
Sbjct: 281 RENYTKKLQSDSIKERQLGTATYLIDKLALRVGNEKDEDEADTVGCCSLRVEHI 334
[137][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 199 bits (505), Expect = 1e-49
Identities = 95/170 (55%), Positives = 123/170 (72%), Gaps = 1/170 (0%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR+E VGNFRVEPP LF GRG+HP TG VK+R+ PE VT+N+G +A +P P PGH W
Sbjct: 409 DGRKEKVGNFRVEPPGLFRGRGEHPKTGTVKKRVMPEQVTINIGKDAKVP-APPPGHKWK 467
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H++ TWLA W++++ G YKYV L+A S KG +D KFEKAR LK I IR +Y
Sbjct: 468 AVQHDNKATWLAMWQENVNGNYKYVMLAANSTVKGQADFKKFEKARDLKKHIDRIRADYT 527
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
+ ++ RQR+TA+YLID+ ALR GNEK E+EA+TVGCCSL+ EH+
Sbjct: 528 RELKSEVMADRQRATAMYLIDRFALRAGNEKDTENEAETVGCCSLKFEHV 577
[138][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 199 bits (505), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 338 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[139][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 199 bits (505), Expect = 1e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 338 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[140][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 198 bits (504), Expect = 2e-49
Identities = 91/178 (51%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N ++ IP
Sbjct: 346 KEYGYCVMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDSKIP-A 404
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 405 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 464
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 465 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 522
[141][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 198 bits (504), Expect = 2e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 487 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPP- 545
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 546 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 605
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 606 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 663
[142][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 198 bits (504), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 144 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 202
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 203 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 262
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 263 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 320
[143][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 198 bits (504), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 330 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 388
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 389 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 448
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 449 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 506
[144][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 198 bits (504), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 376 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 434
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 435 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 494
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 495 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 552
[145][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 198 bits (504), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 338 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[146][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 198 bits (504), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 338 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 457 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 514
[147][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 198 bits (504), Expect = 2e-49
Identities = 91/177 (51%), Positives = 122/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG +E +GNFR+EPP LF GRG+HP G +KRRI DV++N G + +P+
Sbjct: 636 KEYGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIAAADVSINCGKQSKVPQP 695
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P+ G W ++ H++ VTWLA W +++ G KY+ L+ S KG DH K+E AR+L I
Sbjct: 696 PMGGR-WKEVRHDNTVTWLASWTENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVI 754
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 755 DKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHV 811
[148][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina
RepID=B2AY06_PODAN
Length = 904
Score = 198 bits (504), Expect = 2e-49
Identities = 95/170 (55%), Positives = 123/170 (72%), Gaps = 1/170 (0%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR+E VGNFRVEPP LF GRG+HP TG VK+R+ PE VT+N+G A +P+ P GH W
Sbjct: 406 DGRKEKVGNFRVEPPGLFRGRGEHPKTGTVKKRVMPEQVTINIGKEAKVPDPPA-GHKWK 464
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H++ TWLA W++++ G YKYV L+A S KG +D+ KFEKAR+L IA IR +Y
Sbjct: 465 AVQHDNKATWLAMWQENVNGNYKYVMLAANSTVKGQADYKKFEKARELNKHIARIRADYT 524
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
++ RQR+TA+YLIDK ALR GNEK E+EA+TVGCCSL+ EH+
Sbjct: 525 AELKSEIMAERQRATAMYLIDKFALRAGNEKDTENEAETVGCCSLKFEHV 574
[149][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 198 bits (503), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 341 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 399
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 400 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 459
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 460 DRIRTQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 517
[150][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 198 bits (503), Expect = 2e-49
Identities = 92/178 (51%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E +GNFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P+
Sbjct: 322 QEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPK- 380
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWLA W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 381 PPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 440
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 441 DRIRTQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 498
[151][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 198 bits (503), Expect = 2e-49
Identities = 96/176 (54%), Positives = 120/176 (68%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+T A +DGR E VGNFRVEPP LF GRG+HP GK+KRR+ PED+T+N+G +A +PE P
Sbjct: 76 YTWATIDGRREKVGNFRVEPPGLFRGRGEHPKMGKIKRRVVPEDITINIGKDAKVPEPPA 135
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH+W +IHN TWLAGW D I +KYV A S K SD K+EKAR L I
Sbjct: 136 -GHSWKAVIHNDTATWLAGWNDVINVKDWKYVQFGATSTVKAESDQKKYEKARSLHKYIE 194
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y++ ++ KE+ Q + A YL+DKLALR G EK ED ADTVG C+LR H+
Sbjct: 195 KIRKDYKRNMMSESKEMAQLAVATYLVDKLALRAGGEKDEDLADTVGVCTLRAGHI 250
[152][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 198 bits (503), Expect = 2e-49
Identities = 92/177 (51%), Positives = 120/177 (67%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +DG +E +GNFR+EPP LF GRG+HP G VKRR+ PEDV +N G + P+
Sbjct: 543 KEYGTCSIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMVKRRVMPEDVIINCGKESVWPKA 602
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H++ V+WLA W +++ G KYV L+ S KG D K+E AR+L I
Sbjct: 603 P-EGHRWKEVRHDNSVSWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARRLLKHI 661
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K +RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 662 DKIRDTYRDEWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 718
[153][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 197 bits (502), Expect = 3e-49
Identities = 90/178 (50%), Positives = 123/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NF++EPP LF GRG+HP G +KRRI PED+ +N ++ +P
Sbjct: 337 KEYGYCVMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDSKVPP- 395
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 396 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 455
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 456 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 513
[154][TOP]
>UniRef100_A0CF77 Chromosome undetermined scaffold_174, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CF77_PARTE
Length = 725
Score = 197 bits (502), Expect = 3e-49
Identities = 99/174 (56%), Positives = 124/174 (71%), Gaps = 2/174 (1%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
ALVDG E VGN+ +E P LF GRG+HP G +K RI PE++T+NL AP+P+C +PGH
Sbjct: 161 ALVDGCLERVGNYTLEQPTLFKGRGEHPKAGLLKARIFPEELTVNLSTQAPVPQCKLPGH 220
Query: 196 NWGKIIHNSCVTWLAGWKDSIT--GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASI 369
+WGKI+H + VTWL + DS +KYV +A S FK M+D K+EKAR+LK+ I I
Sbjct: 221 SWGKIVHRNDVTWLFSYVDSSIRKDNHKYVQFAATSRFKQMNDKRKYEKARRLKNQIDQI 280
Query: 370 RKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
R+ Y K + + RQ TA YLIDKLALRVGN+K EDEADTVGCCSLRVEH+
Sbjct: 281 RENYTKKLQSDSIKERQLGTATYLIDKLALRVGNDKDEDEADTVGCCSLRVEHI 334
[155][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 197 bits (501), Expect = 4e-49
Identities = 91/177 (51%), Positives = 121/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ + +DG +E +GNFR+EPP LF GRG+HP G VKRR+ PEDV +N ++ P+
Sbjct: 538 KEYGICNIDGHKEKIGNFRIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCAKDSVYPKA 597
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H++ V+WLA W +++ G KYV L+ S KG D K+E AR+L I
Sbjct: 598 P-EGHRWKEVRHDNTVSWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARRLLKHI 656
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K +RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 657 DKIRDTYRDEWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 713
[156][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 197 bits (501), Expect = 4e-49
Identities = 91/178 (51%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NFR+EPP LF GRGDHP GK+K+RI PED+ +N ++ IP
Sbjct: 392 QEYGYCIMDNHKERIANFRIEPPGLFRGRGDHPKMGKLKKRIMPEDIIINCSKDSKIPVA 451
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H+ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 452 PA-GHKWKEVRHDGKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKMCV 510
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR Y++ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 511 EKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 568
[157][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 197 bits (500), Expect = 5e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+Q+ ++D +E + NFR+EPP LF GRGDHP G +KRRI+P+D+ +N ++ PE
Sbjct: 326 QQYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPQDIIINCSKDSKYPE- 384
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 385 PPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 444
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 445 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 502
[158][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 197 bits (500), Expect = 5e-49
Identities = 91/178 (51%), Positives = 122/178 (68%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+Q+ ++D +E + NFR+EPP LF GRGDHP G +KRRI+P+D+ +N ++ PE
Sbjct: 324 QQYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPQDIIINCSKDSKYPE- 382
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 383 PPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 442
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 443 DRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 500
[159][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 197 bits (500), Expect = 5e-49
Identities = 97/177 (54%), Positives = 123/177 (69%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
QF ++VDG E VGNF +EPP F GRG+HP GK+K R+ PE V+LNL AP+P CP
Sbjct: 139 QFGFSIVDGHIERVGNFNMEPPGAFRGRGEHPKMGKLKSRVLPEQVSLNLSECAPVPPCP 198
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
VPGH W + H+ WLA WK++I KY+ L+A S+FKG SD +K+ KA L I
Sbjct: 199 VPGHAWSDVRHDPRGQWLATWKENINNQSKYMQLAAQSSFKGKSDRSKYSKAGLLCKNIE 258
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK Y+K +K EV+Q +TA ++ID+LALRVG EK ++EADTVGCCSLRVEHL
Sbjct: 259 KIRKSYKKDLKSKDMEVKQLATATWVIDRLALRVGGEKDTDEEADTVGCCSLRVEHL 315
[160][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 196 bits (499), Expect = 7e-49
Identities = 101/178 (56%), Positives = 129/178 (72%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIP--EC 180
+ ALVD +E VGNFR+EPP LF GRG+HP +G +K+RI E+VTLN+ +AP+P +
Sbjct: 173 YIYALVDWIKEKVGNFRIEPPGLFRGRGEHPKSGMLKKRIFSEEVTLNVAEDAPVPKVDS 232
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GH W + H+S VTWLA +KDSI +KY++LSA S FKGMSD+ K+EKAR+LK+ I
Sbjct: 233 SIIGHAWKDVFHDSNVTWLAYYKDSINNQFKYIFLSASSGFKGMSDYNKYEKARKLKNFI 292
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
+IR +Y K + RQ TA YLID LALRVG EK E+EADTVGCCSLRVEH+
Sbjct: 293 HAIRDDYNKKMKSNDIIHRQLGTATYLIDFLALRVGGEKDIEEEADTVGCCSLRVEHI 350
[161][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 196 bits (499), Expect = 7e-49
Identities = 93/176 (52%), Positives = 122/176 (69%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ VA +DG ++ +GNFR+EPP+LF GRG HP G++K+R+ PEDV +N ++ IP+ P
Sbjct: 334 YGVAYIDGHKQKIGNFRIEPPDLFRGRGGHPKMGRLKKRVNPEDVIINCSKDSEIPK-PP 392
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H++ VTWL W D+I G KY+ L+ S KG D+ KFE AR+LK + S
Sbjct: 393 EGHRWKEVRHDNTVTWLCSWTDNILGSIKYIMLNPSSKIKGEKDYEKFETARRLKDIVGS 452
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR+ Y K +K VRQR+ ALY IDKLALR GNEK DE ADTVGCCSLR EH+
Sbjct: 453 IRENYTKDLKSKEMRVRQRAVALYFIDKLALRAGNEKDVDEAADTVGCCSLRCEHI 508
[162][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 196 bits (499), Expect = 7e-49
Identities = 96/170 (56%), Positives = 124/170 (72%), Gaps = 1/170 (0%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR+E VGNFRVEPP LF GRG+HP TG +K R+ PE VT+N+G A +PE P GH W
Sbjct: 407 DGRKEKVGNFRVEPPALFRGRGEHPKTGTIKERVPPEAVTINIGKGAKVPEPPA-GHKWK 465
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H++ TWLA W++++ G YKYV L+A SA KG +D KFEKAR+LK I IR +Y
Sbjct: 466 AVQHDNKATWLAMWQENVNGNYKYVMLAANSAVKGQADFKKFEKARELKKHIDRIRADYT 525
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
+ ++ RQR+TA+Y IDKLALR GNEK E+EA+TVGCCSL+VE++
Sbjct: 526 RELRSEIMADRQRATAMYFIDKLALRAGNEKDTENEAETVGCCSLKVENV 575
[163][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 196 bits (499), Expect = 7e-49
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 338 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS- 396
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 397 PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 456
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTV CCSLRVEH+
Sbjct: 457 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHI 514
[164][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 196 bits (498), Expect = 9e-49
Identities = 91/177 (51%), Positives = 121/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +DG +E +GNF++EPP LF GRG+HP G +K+R+ PEDV +N ++ IP+
Sbjct: 320 KEYGFCTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGMLKKRVVPEDVLINCSKDSNIPK- 378
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H+ VTWLA W +++ G KYV L+ S KG D K+E AR+L I
Sbjct: 379 PPPGHKWKEVRHDFGVTWLASWIENVQGQVKYVMLNPSSKLKGEKDWQKYETARRLAKSI 438
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR+ Y W ++ VRQRS ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 439 DKIRENYINDWKSREMHVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 495
[165][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 196 bits (498), Expect = 9e-49
Identities = 93/178 (52%), Positives = 125/178 (70%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +D E +GNF++EPP LF GRGDHP G +K+RI PED+ +N ++ IPE
Sbjct: 74 QEYGYCSMDHHRERIGNFKIEPPALFRGRGDHPKQGMLKKRILPEDIIINCSKDSKIPE- 132
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWLA W +++ G KY+ L+A S KG D K+E AR+LK +
Sbjct: 133 PPPGHKWKEVRHDNTVTWLASWTENVQGSVKYIMLNANSKLKGEKDWEKYEVARKLKHHV 192
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IRK YR+ + +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 193 VTIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 250
[166][TOP]
>UniRef100_Q0V9D3 Putative uncharacterized protein (Fragment) n=1 Tax=Xenopus
(Silurana) tropicalis RepID=Q0V9D3_XENTR
Length = 495
Score = 196 bits (498), Expect = 9e-49
Identities = 93/178 (52%), Positives = 125/178 (70%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ +D E +GNF++EPP LF GRGDHP G +K+RI PED+ +N ++ IPE
Sbjct: 252 QEYGYCSMDHHRERIGNFKIEPPALFRGRGDHPKQGMLKKRILPEDIIINCSKDSKIPE- 310
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PGH W ++ H++ VTWLA W +++ G KY+ L+A S KG D K+E AR+LK +
Sbjct: 311 PPPGHKWKEVRHDNTVTWLASWTENVQGSVKYIMLNANSKLKGEKDWEKYEVARKLKHHV 370
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IRK YR+ + +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 371 VTIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 428
[167][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 196 bits (497), Expect = 1e-48
Identities = 90/171 (52%), Positives = 122/171 (71%), Gaps = 1/171 (0%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DG ++ VGNFR+EPP LF GRGDHP GK+K+R+ ++V +N+G A +P+ P G W
Sbjct: 292 MDGHKQKVGNFRIEPPGLFRGRGDHPKQGKLKKRVSAKEVIINIGKEAKVPQ-PPEGQKW 350
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEY 381
+ H++ V+WLA W ++I GGYKYV L+A + KG D K+E AR+LK C+ +IR+ Y
Sbjct: 351 KAVQHDNTVSWLACWVENIAGGYKYVMLNAATRLKGEKDWQKYETARKLKECVETIRENY 410
Query: 382 RKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
W +K ++RQR A+Y IDKLALR G+EK E E ADTVGCCSLRVEH+
Sbjct: 411 INDWKSKEMKIRQRGVAMYFIDKLALRAGHEKEEGESADTVGCCSLRVEHI 461
[168][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 196 bits (497), Expect = 1e-48
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 575 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 634
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 635 PT-GHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 693
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 694 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 751
[169][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 196 bits (497), Expect = 1e-48
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NF++EPP LF GRG+HP G +KRRI PED+ +N +A +P
Sbjct: 323 KEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 382
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 383 PT-GHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 441
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR+ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 442 DKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 499
[170][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 195 bits (496), Expect = 1e-48
Identities = 95/175 (54%), Positives = 121/175 (69%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L++G +E VGNFR+EPP LF GRG HP TGK+KRR+ PEDVTLNL IPE P
Sbjct: 291 YKTCLLNGHKEQVGNFRIEPPGLFRGRGAHPKTGKLKRRVMPEDVTLNLSEGCKIPE-PP 349
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H++ V+WLA WK++I +KYV +A S+ KG+SD KFE +R+L+ I
Sbjct: 350 QGHKWAEVRHDNTVSWLAMWKENIADSFKYVRFAANSSIKGLSDFKKFETSRKLRYHIDE 409
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K + RQ +TA YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 410 IRKDYTKMLKDPLMQNRQMATACYLIDIFALRAGGEKGDDEADTVGCCSLRYEHI 464
[171][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 195 bits (496), Expect = 1e-48
Identities = 95/175 (54%), Positives = 121/175 (69%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L++G +E VGNFR+EPP LF GRG HP TGK+KRR+ PEDVTLNL IPE P
Sbjct: 291 YKTCLLNGHKEQVGNFRIEPPGLFRGRGAHPKTGKLKRRVMPEDVTLNLSEGCKIPE-PP 349
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H++ V+WLA WK++I +KYV +A S+ KG+SD KFE +R+L+ I
Sbjct: 350 QGHKWAEVRHDNTVSWLAMWKENIADSFKYVRFAANSSIKGLSDFKKFETSRKLRYHIDE 409
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IRK+Y K + RQ +TA YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 410 IRKDYTKMLKDPLMQNRQMATACYLIDIFALRAGGEKGDDEADTVGCCSLRYEHI 464
[172][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 195 bits (495), Expect = 2e-48
Identities = 96/175 (54%), Positives = 120/175 (68%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L++GR+E VGNFRVEPP LF GRG HP TGK+K+R+ PED+TLNL +PE P
Sbjct: 256 YKTCLLNGRKEQVGNFRVEPPGLFRGRGAHPKTGKLKKRVYPEDITLNLSKECKVPE-PP 314
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG++ H++ V WLA WK++I+ KYV +A S+ KG SD KFE AR LK I +
Sbjct: 315 AGHKWGEVRHDNTVAWLAMWKENISDSLKYVRFAANSSVKGQSDFKKFETARNLKFHIDA 374
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y K + RQ +TA YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 375 IRTDYTKLLKDPLMQNRQMATATYLIDVFALRAGGEKGDDEADTVGCCSLRYEHI 429
[173][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 195 bits (495), Expect = 2e-48
Identities = 96/175 (54%), Positives = 120/175 (68%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ L++GR+E VGNFRVEPP LF GRG HP TGK+K+R+ PED+TLNL +PE P
Sbjct: 256 YKTCLLNGRKEQVGNFRVEPPGLFRGRGAHPKTGKLKKRVYPEDITLNLSKECKVPE-PP 314
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH WG++ H++ V WLA WK++I+ KYV +A S+ KG SD KFE AR LK I +
Sbjct: 315 AGHKWGEVRHDNTVAWLAMWKENISDSLKYVRFAANSSVKGQSDFKKFETARNLKFHIDA 374
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y K + RQ +TA YLID ALR G EK +DEADTVGCCSLR EH+
Sbjct: 375 IRTDYTKLLKDPLMQNRQMATATYLIDVFALRAGGEKGDDEADTVGCCSLRYEHI 429
[174][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 194 bits (494), Expect = 3e-48
Identities = 90/178 (50%), Positives = 119/178 (66%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D E + NFR+EPP LF GRGDHP GK+K+RI PED+ +N ++ P
Sbjct: 355 QEYGFCVMDNHRERIANFRIEPPGLFRGRGDHPKMGKLKKRIMPEDIIINCSKDSKYPVA 414
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ H+ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 415 PA-GHKWKEVRHDGKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKMCV 473
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR Y++ W +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 474 EKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 531
[175][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 194 bits (494), Expect = 3e-48
Identities = 93/177 (52%), Positives = 120/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F L+D E +GNF++EPP LF GRG+HP G +K+RIQPED+ +N A IP P
Sbjct: 213 EFGYCLLDHHRERIGNFKIEPPGLFRGRGEHPKQGMLKKRIQPEDIIINCSKEACIP-VP 271
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWL W ++I G KY+ L+A S KG D K+E AR+LKSC+
Sbjct: 272 PAGHRWKEVRHDNTVTWLVSWTENIQGSIKYIMLNANSKLKGEKDWEKYEVARKLKSCVD 331
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IR +YR ++ RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 332 NIRSQYRSDLKSRQMSTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 388
[176][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 194 bits (494), Expect = 3e-48
Identities = 93/177 (52%), Positives = 120/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F L+D E +GNF++EPP LF GRG+HP G +K+RIQPED+ +N A IP P
Sbjct: 203 EFGYCLLDHHRERIGNFKIEPPGLFRGRGEHPKQGMLKKRIQPEDIIINCSKEACIP-VP 261
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWL W ++I G KY+ L+A S KG D K+E AR+LKSC+
Sbjct: 262 PAGHRWKEVRHDNTVTWLVSWTENIQGSIKYIMLNANSKLKGEKDWEKYEVARKLKSCVD 321
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IR +YR ++ RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 322 NIRSQYRSDLKSRQMSTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 378
[177][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 194 bits (494), Expect = 3e-48
Identities = 93/176 (52%), Positives = 120/176 (68%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ +A++DG + V NFR+EPP +F GRG HP G +K+RI PEDV +N G + IP+ P
Sbjct: 308 YGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPK-PP 366
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH W ++ H++ VTWL W +S+ G KY+ L+ S KG D K+E AR+LK I
Sbjct: 367 PGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGG 426
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR+ Y + +K VRQR+TALY IDKLALR GNEK DE ADTVGCCSLRVEH+
Sbjct: 427 IRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHI 482
[178][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 194 bits (494), Expect = 3e-48
Identities = 93/176 (52%), Positives = 120/176 (68%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ +A++DG + V NFR+EPP +F GRG HP G +K+RI PEDV +N G + IP+ P
Sbjct: 380 YGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPK-PP 438
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH W ++ H++ VTWL W +S+ G KY+ L+ S KG D K+E AR+LK I
Sbjct: 439 PGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGG 498
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR+ Y + +K VRQR+TALY IDKLALR GNEK DE ADTVGCCSLRVEH+
Sbjct: 499 IRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHI 554
[179][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 194 bits (493), Expect = 3e-48
Identities = 91/178 (51%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P
Sbjct: 329 QEYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPT- 387
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 388 PPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 447
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W +K ++RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEHL
Sbjct: 448 DRIRSQYRDDWKSKEMKIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHL 505
[180][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 194 bits (493), Expect = 3e-48
Identities = 87/177 (49%), Positives = 121/177 (68%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ + ++DG +E +GNF++EPP LF GRG+HP G VKRR+ PEDV +N ++ IP
Sbjct: 561 KEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPS- 619
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ V+WLA W +++ G KY+ L+ S KG D K+E AR+L I
Sbjct: 620 PPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHI 679
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR W +K +RQR+ A+Y IDKLALR GNEK +D+ADTVGCCSLR EH+
Sbjct: 680 DKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHI 736
[181][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 194 bits (493), Expect = 3e-48
Identities = 91/176 (51%), Positives = 123/176 (69%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ +A++DG +E + NFR+EPP +F GRG HP G +K+RI PEDV +N G ++ IP+ P+
Sbjct: 399 YGIAIIDGHKEKIANFRIEPPGVFRGRGGHPKMGFIKKRIVPEDVIVNCGKDSVIPKPPL 458
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
GH W ++ H++ V+WL W +S+ G KY+ L+A S KG D+ K+E AR+LK I
Sbjct: 459 -GHKWKEVRHDNTVSWLCSWTESVLGQNKYIMLNASSKIKGSKDYEKYETARRLKKKIGG 517
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR+ Y W +K +RQR+TALY IDKLALR GNEK DE ADTVGCCSLR EH+
Sbjct: 518 IRERYIADWKSKEMRIRQRATALYFIDKLALRAGNEKDVDESADTVGCCSLRYEHI 573
[182][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 194 bits (492), Expect = 4e-48
Identities = 92/177 (51%), Positives = 122/177 (68%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++D E +GNF++EPP LF GRGDHP G +K+RI+PEDV +N + IPE P
Sbjct: 103 EYGFCVLDHHRERIGNFKIEPPGLFRGRGDHPKQGMLKKRIRPEDVIINCSKESRIPEAP 162
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H+ VTWLA W +++ G KYV L+A S KG D K+E AR+LK+C+
Sbjct: 163 A-GHKWKEVRHDKTVTWLASWTENVQGSCKYVMLNANSKLKGEKDWEKYEVARKLKTCVD 221
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IR +Y++ +K RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 222 AIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 278
[183][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 194 bits (492), Expect = 4e-48
Identities = 92/177 (51%), Positives = 122/177 (68%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++D E +GNF++EPP LF GRGDHP G +K+RI+PEDV +N + IPE P
Sbjct: 181 EYGFCVLDHHRERIGNFKIEPPGLFRGRGDHPKQGMLKKRIRPEDVIINCSKESRIPEAP 240
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H+ VTWLA W +++ G KYV L+A S KG D K+E AR+LK+C+
Sbjct: 241 A-GHKWKEVRHDKTVTWLASWTENVQGSCKYVMLNANSKLKGEKDWEKYEVARKLKTCVD 299
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IR +Y++ +K RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 300 AIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 356
[184][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 194 bits (492), Expect = 4e-48
Identities = 92/176 (52%), Positives = 118/176 (67%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+T A +DGR E VGNFR+EPP LF GRG+HP GK+KRR+ PED+T+N+G +A +P P
Sbjct: 356 YTWATIDGRREKVGNFRIEPPGLFRGRGEHPKMGKIKRRVMPEDITINIGKDARVPP-PP 414
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSIT-GGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
PGH+W +IHN TWLAGW D I +KYV A S K SD K+EKAR L I
Sbjct: 415 PGHSWKAVIHNDTATWLAGWNDVINVKDWKYVQFGATSTVKAESDQKKYEKARSLHKFIE 474
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +Y++ ++ +E+ Q + YL+DKLALR G EK ED ADTVG C+LR H+
Sbjct: 475 KIRADYKRNMQSESREMAQLAVTTYLVDKLALRAGGEKDEDLADTVGVCTLRAGHI 530
[185][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 193 bits (491), Expect = 6e-48
Identities = 93/177 (52%), Positives = 122/177 (68%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ +D E +GNF++EPP LF GRGDHP G +K+RI PED+ +N ++ IPE P
Sbjct: 75 EYGYCAMDHHREKIGNFKIEPPALFRGRGDHPKQGMLKKRILPEDIIINCSKDSKIPE-P 133
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
PGH W ++ H++ VTWLA W +++ G KY+ L+A S KG D K+E AR+LK
Sbjct: 134 PPGHKWKEVRHDNTVTWLASWTENVQGSVKYIMLNANSKLKGEKDWEKYEIARKLKHHAE 193
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IRK YR+ + +K +VRQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 194 KIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAGNEKEEGESADTVGCCSLRVEHI 250
[186][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 192 bits (488), Expect = 1e-47
Identities = 88/178 (49%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++DG + VGNF++EPP LF GRGDHP GK+KRRI+ +D+ +N+G +A +P
Sbjct: 131 QEYGFCIIDGHRQRVGNFKIEPPGLFRGRGDHPKQGKIKRRIEAKDIIINIGKDAKLP-A 189
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ +++ VTWLA W ++I G KY+ L+ S K D+ K+E AR+LK I
Sbjct: 190 PPPGQKWKEVRYDNKVTWLASWTENINGSIKYIMLNPTSKIKAEKDYQKYETARKLKRYI 249
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR++Y+ W +K +RQRS ALY ID+LALR G+EK E E ADTVGCCSLR EH+
Sbjct: 250 DKIRQDYKADWKSKEMRIRQRSAALYFIDRLALRAGHEKEEGESADTVGCCSLRYEHI 307
[187][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 192 bits (487), Expect = 2e-47
Identities = 93/177 (52%), Positives = 120/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ A++DGR E VGNFRVEPP LF GRG+HP G++K+RI PED+T+N+G P P+ P
Sbjct: 283 KYNWAVIDGRRERVGNFRVEPPGLFRGRGEHPKMGRIKKRIMPEDITINIGKGVPAPD-P 341
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSI-TGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
PGH W +IHN VTWL GW D+I T +KYV A S+ K SD K+EKAR+LK +
Sbjct: 342 GPGHKWKDVIHNDTVTWLCGWNDTINTKDWKYVQFGAMSSIKAESDIQKYEKARKLKLAV 401
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+IR++Y K +Q + YL+DKLALR G EK ED ADTVG C+LRV H+
Sbjct: 402 DAIRRDYFKKMKTGDMLAKQLAVTTYLVDKLALRAGGEKDEDLADTVGVCTLRVGHV 458
[188][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 192 bits (487), Expect = 2e-47
Identities = 95/170 (55%), Positives = 121/170 (71%), Gaps = 1/170 (0%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DGR+E VGN RVE P LF GRGDHP TG +K+R+ PE +T+N+G A +PE P GH W
Sbjct: 376 DGRKEKVGNPRVEIPGLFRGRGDHPKTGCIKKRVLPEQITINIGKEAKVPEPPA-GHKWK 434
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
+ H++ TWLA W+++I G YKYV L+A S KG +D KFEKAR+LK I IR +Y
Sbjct: 435 AVQHDNKATWLAMWQENINGHYKYVMLAANSTVKGKADFKKFEKARELKKYIDRIRADYT 494
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
K ++ RQR+TA+YLIDK ALR GNEK E+EA+TVGCCSL+ EH+
Sbjct: 495 KDLKSEVMADRQRATAMYLIDKFALRAGNEKDTENEAETVGCCSLKYEHV 544
[189][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 191 bits (486), Expect = 2e-47
Identities = 91/178 (51%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
R+F ++DG +E +GNF++EPP LF GRGDHP G +KRRI PEDV +N ++ IPE
Sbjct: 172 REFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPEP 231
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W +S+ KY+ L+ S KG + KFE AR+L+ +
Sbjct: 232 PA-GHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFV 290
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQR+ ALY IDKLALR GNEK + E ADTVGCCSLRVEH+
Sbjct: 291 DEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHV 348
[190][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 191 bits (485), Expect = 3e-47
Identities = 92/177 (51%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG E +GNF+ EPP LF GRGDHP G +K+RI PEDV +N ++ IPE P
Sbjct: 165 EYGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKKRIMPEDVIINCSKDSKIPEPP 224
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
V GH W ++ ++ VTWLA W ++I KY+ L+ S KG D KFE AR+LK +
Sbjct: 225 V-GHKWKEVRFDNTVTWLASWTENIQNSLKYIMLNPSSKLKGEKDWQKFEVARKLKDVVH 283
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +Y+ W +K + RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 284 KIRAQYQADWKSKEMKKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 340
[191][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 191 bits (485), Expect = 3e-47
Identities = 92/177 (51%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG E +GNF+ EPP LF GRGDHP G +K+RI PEDV +N ++ IPE P
Sbjct: 165 EYGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKKRIMPEDVIINCSKDSKIPEPP 224
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
V GH W ++ ++ VTWLA W ++I KY+ L+ S KG D KFE AR+LK +
Sbjct: 225 V-GHKWKEVRFDNTVTWLASWTENIQNSLKYIMLNPSSKLKGEKDWQKFEVARKLKDVVH 283
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +Y+ W +K + RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 284 KIRAQYQADWKSKEMKKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 340
[192][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 191 bits (485), Expect = 3e-47
Identities = 97/191 (50%), Positives = 124/191 (64%), Gaps = 19/191 (9%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVP-- 189
A++DG E VG F +EPP LF GRG+HP G +K RIQPE V +N+ +AP+P+C VP
Sbjct: 256 AILDGFREKVGQFMIEPPTLFKGRGEHPKMGMMKGRIQPEAVVINISKDAPVPKCSVPDC 315
Query: 190 ----------------GHNWGKIIHNSCVTWLAGWKD-SITGGYKYVWLSAGSAFKGMSD 318
GH W +I+H VTWLA +KD S+ +KY++LSA S K +D
Sbjct: 316 IHICRQIFNEFPKKQLGHGWSEIVHKQDVTWLASYKDDSVKKQHKYIFLSAESKLKAEND 375
Query: 319 HAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADT 498
K+EKAR+LK+ I IR+ Y + + RQ TA YLIDKLALRVGNEK+E+EADT
Sbjct: 376 KKKYEKARRLKNLIGQIRENYERKLRSSDPVDRQLGTATYLIDKLALRVGNEKSEEEADT 435
Query: 499 VGCCSLRVEHL 531
VGCCSLRVEH+
Sbjct: 436 VGCCSLRVEHI 446
[193][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 191 bits (485), Expect = 3e-47
Identities = 93/176 (52%), Positives = 121/176 (68%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ LVDG E + NFR+EPP LF GRGDHP G +KRR+Q D+ +N G ++ IP P
Sbjct: 200 KYGFCLVDGHRERISNFRLEPPGLFRGRGDHPKMGMIKRRVQACDIIINCGRDSKIP-MP 258
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
G W ++ H++ VTWLA W D++ G KY+ L++ S + SDH K+E AR+L I
Sbjct: 259 PRGQMWKEVRHDNTVTWLASWVDNVQGQSKYIILNSWSKIRCESDHNKYETARRLHKFID 318
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR YR+ W +K VRQR+ ALY IDKLALRVGNEK +D+ADTVGCCSLRVEH+
Sbjct: 319 KIRATYREEWKSKDIFVRQRAVALYFIDKLALRVGNEKEKDQADTVGCCSLRVEHV 374
[194][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 191 bits (484), Expect = 4e-47
Identities = 92/177 (51%), Positives = 118/177 (66%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F ++DG E +GNF+ EPP LF GRGDHP G +K+RI PEDV +N ++ IPE P
Sbjct: 261 EFGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGLLKKRIMPEDVIINCSKDSKIPE-P 319
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ ++ VTWLA W ++I KY+ L+ S KG D K+E AR+LK +
Sbjct: 320 PSGHKWKEVRFDNTVTWLASWTENIQNSIKYIMLNPSSKLKGEKDWQKYELARRLKGVVD 379
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W +K + RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 380 KIRAQYRADWKSKEMKKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 436
[195][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 190 bits (482), Expect = 6e-47
Identities = 91/178 (51%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNF++EPP LF GRGDHP G +KRRI PEDV +N ++ IPE
Sbjct: 74 QEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEP 133
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W +SI KY+ L+ S KG + KFE AR+L+ +
Sbjct: 134 PA-GHQWKEVRSDNTVTWLAAWTESIQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFV 192
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQR+ ALY IDKLALR GNEK + E ADTVGCCSLRVEH+
Sbjct: 193 DEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHV 250
[196][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 189 bits (481), Expect = 8e-47
Identities = 91/177 (51%), Positives = 120/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG E +GNF+ EPP LF GRG+HP G +K+RI PEDV +N ++ IPE P
Sbjct: 234 EYGYCILDGHREKIGNFKTEPPGLFRGRGEHPKMGMLKKRIMPEDVIINCSKDSKIPE-P 292
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ ++ VTWLA W ++I KY+ L+ S KG D K+E AR+LK +
Sbjct: 293 PEGHKWKEVRFDNTVTWLASWTENIQNTLKYIMLNPSSKLKGEKDWEKYEVARRLKDVVH 352
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+IR +YRK W +K + RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 353 TIRAQYRKDWKSKEIKKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 409
[197][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 189 bits (481), Expect = 8e-47
Identities = 92/173 (53%), Positives = 121/173 (69%), Gaps = 1/173 (0%)
Frame = +1
Query: 16 ALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
A +DGR E VGN++VEPP LF GRG+HP G+VK+RI PED+ +N+G A +PE P+PGH
Sbjct: 234 ATIDGRRERVGNYKVEPPGLFRGRGEHPKMGRVKKRIMPEDIIINIGKGAKVPE-PLPGH 292
Query: 196 NWGKIIHNSCVTWLAGWKDSI-TGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIR 372
W +IIHN+ VTWL GW D+I T +KYV A S+ K SD K+EKAR+LK + +IR
Sbjct: 293 KWKQIIHNNTVTWLCGWNDTINTKDWKYVQFGATSSIKAESDIQKYEKARKLKLAVDAIR 352
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
++Y K + +Q + YL+DKLALR G EK +D ADTVG C+LRV H+
Sbjct: 353 RDYFKKMKSGSVLEQQLAVTTYLVDKLALRAGGEKDDDLADTVGVCTLRVGHI 405
[198][TOP]
>UniRef100_C4Q6C8 DNA topoisomerase type I, putative n=2 Tax=Schistosoma mansoni
RepID=C4Q6C8_SCHMA
Length = 587
Score = 189 bits (481), Expect = 8e-47
Identities = 88/176 (50%), Positives = 118/176 (67%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG ++ +GNFR+EPP LF GRG+HP G +K+RI PEDV +N ++ +P P
Sbjct: 258 EYGYCILDGHKQRIGNFRIEPPGLFRGRGNHPKMGMLKKRIMPEDVIINCSKDSKVP-AP 316
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWLA W ++I +KY+ L+ S KG D K+E AR L I
Sbjct: 317 PKGHKWKEVRHDNSVTWLACWTENIQNSFKYIMLNPSSRLKGEKDWKKYETARCLHKVID 376
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +YR + K +RQR+ ALY IDKLALR GNEK EDEADTVGCCSLR EH+
Sbjct: 377 KIRADYRADFKHKEMRIRQRAVALYFIDKLALRAGNEKDEDEADTVGCCSLRYEHI 432
[199][TOP]
>UniRef100_C4Q6C7 DNA topoisomerase type I, putative n=1 Tax=Schistosoma mansoni
RepID=C4Q6C7_SCHMA
Length = 652
Score = 189 bits (481), Expect = 8e-47
Identities = 88/176 (50%), Positives = 118/176 (67%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG ++ +GNFR+EPP LF GRG+HP G +K+RI PEDV +N ++ +P P
Sbjct: 258 EYGYCILDGHKQRIGNFRIEPPGLFRGRGNHPKMGMLKKRIMPEDVIINCSKDSKVP-AP 316
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWLA W ++I +KY+ L+ S KG D K+E AR L I
Sbjct: 317 PKGHKWKEVRHDNSVTWLACWTENIQNSFKYIMLNPSSRLKGEKDWKKYETARCLHKVID 376
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR +YR + K +RQR+ ALY IDKLALR GNEK EDEADTVGCCSLR EH+
Sbjct: 377 KIRADYRADFKHKEMRIRQRAVALYFIDKLALRAGNEKDEDEADTVGCCSLRYEHI 432
[200][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 189 bits (481), Expect = 8e-47
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNF++EPP LF GRGDHP G +KRRI PEDV +N ++ IPE
Sbjct: 74 QEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEP 133
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W +S+ KY+ L+ S KG + KFE AR+L+ +
Sbjct: 134 PA-GHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFV 192
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQR+ ALY IDKLALR GNEK + E ADTVGCCSLRVEH+
Sbjct: 193 DEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHV 250
[201][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 189 bits (481), Expect = 8e-47
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNF++EPP LF GRGDHP G +KRRI PEDV +N ++ IPE
Sbjct: 74 QEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEP 133
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W +S+ KY+ L+ S KG + KFE AR+L+ +
Sbjct: 134 PA-GHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFV 192
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQR+ ALY IDKLALR GNEK + E ADTVGCCSLRVEH+
Sbjct: 193 DEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHV 250
[202][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 189 bits (481), Expect = 8e-47
Identities = 90/178 (50%), Positives = 121/178 (67%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG +E +GNF++EPP LF GRGDHP G +KRRI PEDV +N ++ IPE
Sbjct: 172 QEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEP 231
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W +S+ KY+ L+ S KG + KFE AR+L+ +
Sbjct: 232 PA-GHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFV 290
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQR+ ALY IDKLALR GNEK + E ADTVGCCSLRVEH+
Sbjct: 291 DEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHV 348
[203][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 187 bits (476), Expect = 3e-46
Identities = 92/178 (51%), Positives = 118/178 (66%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F +DG E +GNF+ EPP LF GRGDHP G +KRRI PEDVT+N ++ IP+
Sbjct: 226 QEFGYCTLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRILPEDVTINCSRDSKIPKP 285
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ VTWLA W ++I KYV L+ S KG D K+E AR+LK +
Sbjct: 286 PA-GHQWKEVRSDNTVTWLASWTENIQNSIKYVMLNPSSKLKGEKDWQKYEVARRLKGVV 344
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +YR W ++ + RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 345 DEIRSQYRADWKSREMKKRQCAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHI 402
[204][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 187 bits (476), Expect = 3e-46
Identities = 92/181 (50%), Positives = 121/181 (66%), Gaps = 5/181 (2%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ L+D E +GNF++EPP LF GRG+HP GK+K+RIQPEDV +N + E
Sbjct: 187 EYGYCLLDHHRERIGNFKIEPPGLFRGRGEHPKQGKLKKRIQPEDVIINCSNSRVDRESR 246
Query: 184 VP----GHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLK 351
+P GH W ++ H++ VTWLA W ++I G KY+ L+A S KG D K+E AR+LK
Sbjct: 247 IPVPPAGHRWKEVRHDNTVTWLASWTENIQGSIKYIMLNANSKLKGEKDWEKYEVARKLK 306
Query: 352 SCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEH 528
SC+ +IR +Y ++ RQR+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH
Sbjct: 307 SCVDNIRNQYLMDLKSREMCTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEH 366
Query: 529 L 531
+
Sbjct: 367 I 367
[205][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 186 bits (473), Expect = 7e-46
Identities = 97/176 (55%), Positives = 119/176 (67%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ALVD E VGN RVEPP LF GRG+HP G +KRRI DV LNL +AP+P +
Sbjct: 446 YAYALVDFIREKVGNTRVEPPGLFRGRGEHPKQGMLKRRIFSYDVILNLAEDAPVPRVAL 505
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH W + H++ VTWLA ++DSI KY++L+A S FKG D K+EKAR+LK +
Sbjct: 506 PGHAWKDVFHDNSVTWLAFYRDSINDQVKYMYLAAQSKFKGQQDFLKYEKARKLKLHVDR 565
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y K + RQ TA YLID LALRVG EK ++EADTVGCCSLRVEHL
Sbjct: 566 IRQDYFKKLESTNSLDRQLGTATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHL 621
[206][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 186 bits (473), Expect = 7e-46
Identities = 97/176 (55%), Positives = 119/176 (67%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ALVD E VGN RVEPP LF GRG+HP G +KRRI DV LNL +AP+P +
Sbjct: 446 YAYALVDFIREKVGNTRVEPPGLFRGRGEHPKQGMLKRRIFSYDVILNLAEDAPVPRVAL 505
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH W + H++ VTWLA ++DSI KY++L+A S FKG D K+EKAR+LK +
Sbjct: 506 PGHAWKDVFHDNSVTWLAFYRDSINDQVKYMYLAAQSKFKGQQDFLKYEKARKLKLHVDR 565
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y K + RQ TA YLID LALRVG EK ++EADTVGCCSLRVEHL
Sbjct: 566 IRQDYFKKLESTNSLDRQLGTATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHL 621
[207][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 186 bits (473), Expect = 7e-46
Identities = 97/176 (55%), Positives = 119/176 (67%), Gaps = 1/176 (0%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ALVD E VGN RVEPP LF GRG+HP G +KRRI DV LNL +AP+P +
Sbjct: 446 YAYALVDFIREKVGNTRVEPPGLFRGRGEHPKQGMLKRRIFSYDVILNLAEDAPVPRVAL 505
Query: 187 PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
PGH W + H++ VTWLA ++DSI KY++L+A S FKG D K+EKAR+LK +
Sbjct: 506 PGHAWKDVFHDNSVTWLAFYRDSINDQVKYMYLAAQSKFKGQQDFLKYEKARKLKLHVDR 565
Query: 367 IRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y K + RQ TA YLID LALRVG EK ++EADTVGCCSLRVEHL
Sbjct: 566 IRQDYFKKLESTNSLDRQLGTATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHL 621
[208][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 186 bits (472), Expect = 9e-46
Identities = 96/178 (53%), Positives = 122/178 (68%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC-- 180
+T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP P
Sbjct: 283 YTFALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPAPRLYD 342
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GHNWG I H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LKSC+
Sbjct: 343 DMCGHNWGDIYHDNKVTWLAYYKDSINDQIKYTFLSAQSKFKGYKDFLKYENARKLKSCV 402
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y+ +K +Q TA+YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 403 HKIRKDYQNKMKSKNIINKQLGTAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHV 460
[209][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 185 bits (470), Expect = 2e-45
Identities = 96/178 (53%), Positives = 121/178 (67%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC-- 180
+T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP P
Sbjct: 338 YTFALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPAPRLYD 397
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GHNWG I H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LKSC+
Sbjct: 398 DMCGHNWGDIYHDNKVTWLAYYKDSINDQIKYTFLSAQSKFKGYKDFLKYENARKLKSCV 457
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IRK+Y+ K +Q TA+YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 458 HKIRKDYQNKMKNKNIVNKQLGTAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHV 515
[210][TOP]
>UniRef100_P41511 DNA topoisomerase 1 n=1 Tax=Ustilago maydis RepID=TOP1_USTMA
Length = 1019
Score = 185 bits (470), Expect = 2e-45
Identities = 90/175 (51%), Positives = 117/175 (66%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ + LVDG E+ VGN VEPP LFLGRG HP GKVKRRI P D+T+N + P P+ P
Sbjct: 290 KWKICLVDGVEQRVGNVNVEPPGLFLGRGAHPKAGKVKRRISPGDITINHSADHPAPQPP 349
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
+W +++ VTWLA WK++I G YKYV+L A S FK SD KFEKAR+L + +
Sbjct: 350 AGMGDWAEVVEKKDVTWLAYWKENINGQYKYVFLDATSNFKTNSDREKFEKARKLDTVVK 409
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEH 528
IR++ K +K + RQ +T ++LID +LR GNEK EDEA+T G CSLR EH
Sbjct: 410 QIRRDVNKNLKSKVRHERQIATIVWLIDNFSLRAGNEKGEDEAETYGVCSLRCEH 464
[211][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 184 bits (468), Expect = 3e-45
Identities = 93/186 (50%), Positives = 121/186 (65%), Gaps = 10/186 (5%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ L+D E +GNF++EPP LF GRG+HP GK+K+RIQPEDV +N + IP P
Sbjct: 171 EYGYCLLDHHRERIGNFKIEPPGLFRGRGEHPKQGKLKKRIQPEDVIINCSKESRIP-VP 229
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ VTWLA W ++I G KY+ L+A S KG D K+E AR+LKSC+
Sbjct: 230 PAGHRWKEVRHDNTVTWLASWTENIQGSIKYIMLNANSKLKGEKDWEKYEVARKLKSCVD 289
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLID---------KLALRVGNEKAEDE-ADTVGCCS 513
+IR +Y ++ RQR+ ALY ID KLALR GNEK E E ADTVGCCS
Sbjct: 290 NIRNQYLMDLKSREMCTRQRAVALYFIDKVGVTVVILKLALRAGNEKEEGETADTVGCCS 349
Query: 514 LRVEHL 531
LRVEH+
Sbjct: 350 LRVEHI 355
[212][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 184 bits (468), Expect = 3e-45
Identities = 95/178 (53%), Positives = 122/178 (68%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC-- 180
+T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP+P
Sbjct: 286 YTYALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRLYD 345
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GHNWG I H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LKSC+
Sbjct: 346 NMCGHNWGDIYHDNKVTWLAYYKDSINDQIKYTFLSAQSKFKGYKDLMKYENARKLKSCV 405
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y+ K +Q TA+YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 406 HKIREDYKNKMKNKNIIDKQLGTAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHI 463
[213][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
RepID=B3L6G4_PLAKH
Length = 924
Score = 183 bits (465), Expect = 6e-45
Identities = 94/177 (53%), Positives = 122/177 (68%), Gaps = 3/177 (1%)
Frame = +1
Query: 10 TVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC--P 183
T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP+P
Sbjct: 321 TYALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRLYGD 380
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
+ GH+WG I H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LKSC+
Sbjct: 381 MCGHSWGDIYHDNKVTWLAYYKDSINDQLKYTFLSAQSKFKGYKDFLKYENARKLKSCVH 440
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++Y+ +K +Q TA+YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 441 KIREDYKHKMKSKNILEKQLGTAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHV 497
[214][TOP]
>UniRef100_A8PY85 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
7966 RepID=A8PY85_MALGO
Length = 877
Score = 183 bits (465), Expect = 6e-45
Identities = 87/175 (49%), Positives = 118/175 (67%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ + LVDG E+ GN VEPP LFLGRG HP G+VK RIQPE +T+N + P P+ P
Sbjct: 249 EYKLCLVDGIEQKAGNVTVEPPGLFLGRGAHPKAGRVKTRIQPEQITINHSADHPPPK-P 307
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH+WG+++ VTWLA W+++I GG+KYV+L A S FK SD KFEKAR+L +C+
Sbjct: 308 PKGHSWGEVVERKDVTWLALWRENINGGFKYVFLDASSTFKTESDREKFEKARRLDTCVK 367
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEH 528
+R + K +K + + +T ++LID +LR GNEK EDEA+T G CSLR H
Sbjct: 368 QVRADVLKNLRSKDRLDQMIATIVWLIDNFSLRAGNEKGEDEAETYGVCSLRCGH 422
[215][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 181 bits (460), Expect = 2e-44
Identities = 88/178 (49%), Positives = 117/178 (65%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG E +GNF+ EPP LF GRGDHP G +KRR+ PEDV +N ++ IPE
Sbjct: 165 QEFGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEP 224
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ V WLA W ++I +KY+ L+ S KG D K+E AR+LK +
Sbjct: 225 PA-GHQWKEVRSDNTVMWLAAWVENIQNSFKYIILNPSSKPKGEMDWQKYEVARRLKGVV 283
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +Y+ W + + RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 284 DKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHV 341
[216][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 181 bits (459), Expect = 3e-44
Identities = 89/178 (50%), Positives = 116/178 (65%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG E +GNF+ EPP LF GRGDHP G +KRR+ PEDV +N ++ IPE
Sbjct: 164 QEFGYCVLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEP 223
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ V WLA W + I +KYV L+ S KG D K+E AR+LK +
Sbjct: 224 PA-GHQWKEVRSDNTVMWLAAWVEHIQNSFKYVILNPSSKPKGEMDWQKYEVARRLKGVV 282
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +Y+ W + + RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 283 DKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHI 340
[217][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 181 bits (459), Expect = 3e-44
Identities = 89/178 (50%), Positives = 116/178 (65%), Gaps = 1/178 (0%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F ++DG E +GNF+ EPP LF GRGDHP G +KRR+ PEDV +N ++ IPE
Sbjct: 165 QEFGYCVLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEP 224
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P GH W ++ ++ V WLA W + I +KYV L+ S KG D K+E AR+LK +
Sbjct: 225 PA-GHQWKEVRSDNTVMWLAAWVEHIQNSFKYVILNPSSKPKGEMDWQKYEVARRLKGVV 283
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
IR +Y+ W + + RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 284 DKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHI 341
[218][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax
RepID=A5KB33_PLAVI
Length = 931
Score = 181 bits (458), Expect = 4e-44
Identities = 94/178 (52%), Positives = 120/178 (67%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC-- 180
+T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP+P
Sbjct: 320 YTYALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRLYD 379
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
+ GH WG H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LKSC+
Sbjct: 380 DMCGHCWGDTYHDNKVTWLAYYKDSINDQLKYTFLSAQSKFKGYKDFLKYENARKLKSCV 439
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHL 531
IR++YR K +Q TA+YLID LALRVG EK ++EADTVGCCSLRVEH+
Sbjct: 440 HKIREDYRHKMRNKSILDKQLGTAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHV 497
[219][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 180 bits (456), Expect = 6e-44
Identities = 87/170 (51%), Positives = 115/170 (67%), Gaps = 1/170 (0%)
Frame = +1
Query: 25 DGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWG 204
DG E +GNFR+EPP LF GRG+HP GK+K+RI PE++T+N N+ IP+ P GH W
Sbjct: 60 DGHREKIGNFRLEPPGLFRGRGNHPKMGKLKKRIIPENITINCSKNSKIPKPPA-GHKWK 118
Query: 205 KIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYR 384
++ H++ VTWL W +++ KY+ L+ S KG D K+E AR LKS + IR++Y
Sbjct: 119 EVRHDNAVTWLVSWTENVQNQNKYIMLNPSSRVKGEKDWQKYEVARNLKSKVDRIREDYM 178
Query: 385 KGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
+ + VRQR+ ALY IDKLALR GNEK + E ADTVGCCSLR EH+
Sbjct: 179 RDLKSDEMMVRQRAVALYFIDKLALRAGNEKEDGESADTVGCCSLRCEHI 228
[220][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 176 bits (446), Expect = 9e-43
Identities = 93/179 (51%), Positives = 118/179 (65%), Gaps = 3/179 (1%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F ALVD E V + ++EPP LF GRG HP G +K R+ P+DV LNL +AP+P+
Sbjct: 454 RFNYALVDWVREKVSSNKLEPPGLFKGRGLHPKQGLLKARMFPKDVILNLSKDAPVPKVS 513
Query: 184 V---PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKS 354
GH+W I H++ VTWLA +KDSI +KY++LSA S FKG D K+ KAR+LK+
Sbjct: 514 NFQREGHSWKDIYHDNSVTWLAYYKDSINDQFKYMYLSAQSKFKGFHDFLKYNKARELKA 573
Query: 355 CIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
I IR +Y + +Q TA+YLID LALRVG EK DEADTVGCCSLRVEH+
Sbjct: 574 YIQKIRDDYNTKMLSMDIYEKQLGTAVYLIDFLALRVGGEKDADEADTVGCCSLRVEHI 632
[221][TOP]
>UniRef100_UPI000187DC43 hypothetical protein MPER_08287 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187DC43
Length = 343
Score = 174 bits (441), Expect = 4e-42
Identities = 89/165 (53%), Positives = 114/165 (69%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++T +DGR+E VGNFRVEPP LF GRG+HP G +K R+ PED+ LN+G +AP P
Sbjct: 104 KYTHRFLDGRKEKVGNFRVEPPGLFRGRGEHPKKGSLKYRVCPEDIALNIGKDAPTPIPN 163
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
+PG W I H++ VTWLA ++I +KYV+L+AGS+ KG SD AKFEKAR+LK +
Sbjct: 164 IPG-KWKAIQHDNTVTWLATRTENINQSHKYVFLAAGSSLKGRSDMAKFEKARELKIHVD 222
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADT 498
IR+ Y +K RQR+TA +DKLALR GNEK EDEADT
Sbjct: 223 RIRQNYTVDLKSKVMAERQRATATCFVDKLALRAGNEKGEDEADT 267
[222][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 171 bits (432), Expect = 4e-41
Identities = 91/178 (51%), Positives = 113/178 (63%), Gaps = 3/178 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPV 186
+ ALVD E VG+ R+EPP LF GRG HP G +K R P V LNL +AP+P+ +
Sbjct: 236 YCYALVDWIREKVGSNRMEPPGLFKGRGLHPKQGLLKGRTFPHSVVLNLSKDAPVPKVSM 295
Query: 187 ---PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSC 357
GH W I H+S VTWLA ++D++ KY++ +A S FKG+ D K+ KAR+LK
Sbjct: 296 FERQGHGWSDIFHDSSVTWLAYYRDTVNDQTKYMYPAAQSKFKGLHDFLKYSKARELKKH 355
Query: 358 IASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
I IRK+Y + RQ TA YLID LALRVG EK DEADTVGCCSLRVEH+
Sbjct: 356 IMKIRKDYHGKMRSPEIVDRQLGTATYLIDFLALRVGGEKDADEADTVGCCSLRVEHI 413
[223][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 169 bits (427), Expect = 1e-40
Identities = 93/187 (49%), Positives = 117/187 (62%), Gaps = 11/187 (5%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F ALVD E V + ++EPP LF GRG HP G +K R+ P+DV LNL +AP+P+
Sbjct: 455 RFNYALVDWVREKVSSNKLEPPGLFKGRGLHPKQGLLKSRMFPKDVILNLSKDAPVPKVT 514
Query: 184 V---PGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKS 354
GH+W I H++ VTWLA +KDSI +KY++LSA S FKG D K+ KAR+LK+
Sbjct: 515 NFQREGHSWKDIYHDNSVTWLAYYKDSINDQFKYMYLSAQSKFKGFHDFLKYNKARELKA 574
Query: 355 CIASIRKEYRKGWAAK--------GKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCC 510
I IR +Y +Q TA+YLID LALRVG EK DEADTVGCC
Sbjct: 575 YIQKIRDDYNTKMLCMTIIYTITLDIYEKQLGTAVYLIDYLALRVGGEKDADEADTVGCC 634
Query: 511 SLRVEHL 531
SLRVEH+
Sbjct: 635 SLRVEHI 641
[224][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 162 bits (410), Expect = 1e-38
Identities = 78/140 (55%), Positives = 102/140 (72%), Gaps = 1/140 (0%)
Frame = +1
Query: 106 GKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWGKIIHNSCVTWLAGWKDSITGG-YKYVW 282
G++K+RI P ++TLN+G APIPECP+ G W ++ H++ VTWLA W D I +KYV+
Sbjct: 1 GELKKRIHPCEITLNIGKGAPIPECPIAGERWKEVKHDNTVTWLAFWADPINPKEFKYVF 60
Query: 283 LSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALR 462
L AGS+ KG+SD K+EKAR L I +IR Y K + AK ++RQ + A YLIDKLALR
Sbjct: 61 LGAGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYLIDKLALR 120
Query: 463 VGNEKAEDEADTVGCCSLRV 522
GNEK +DEADTVGCC+L+V
Sbjct: 121 AGNEKDDDEADTVGCCTLKV 140
[225][TOP]
>UniRef100_A9A2H9 2-alkenal reductase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A2H9_NITMS
Length = 551
Score = 160 bits (404), Expect = 7e-38
Identities = 86/176 (48%), Positives = 111/176 (63%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ VA++DG+E VGN+ EPP +F+GRG+HPL G+ K R+ +DVTLNLG A +PE
Sbjct: 123 KYGVAVMDGKEVEVGNYMAEPPGIFIGRGEHPLRGRWKPRVTAKDVTLNLGKEAKVPE-- 180
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
WGKIIH+ WLA W D +T KYVWLS S K D K+EKA +L+ I
Sbjct: 181 ---GKWGKIIHDKDSMWLASWMDFLTQKRKYVWLSDSSDLKQGRDKEKYEKAVKLEKEIE 237
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
I+K K K + +TA YLI K A+RVG+EK EDEADTVG +LR EH+
Sbjct: 238 KIKKAMVKD--MKDSKKNNVATACYLIYKTAMRVGDEKDEDEADTVGATTLRKEHI 291
[226][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E471B7
Length = 879
Score = 157 bits (396), Expect = 6e-37
Identities = 79/140 (56%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
Frame = +1
Query: 115 KRRIQPEDVTLNLGPNAPIPECPVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAG 294
K+RI PEDV +N ++ P P GH W K+IH + VTWLA W ++I G KYV L+
Sbjct: 488 KQRIGPEDVIINCSKDSKWP-IPPEGHKWKKVIHENSVTWLASWTENIQGAIKYVMLNPS 546
Query: 295 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 474
S KG D AK+E AR+LK + IR EYR+ W +K VRQR+ ALY IDKLALR GNE
Sbjct: 547 SRIKGEKDWAKYETARKLKESVDRIRNEYREDWKSKEMRVRQRAVALYFIDKLALRAGNE 606
Query: 475 KAEDE-ADTVGCCSLRVEHL 531
K E E ADTVGCCSLRVEH+
Sbjct: 607 KEEGETADTVGCCSLRVEHI 626
[227][TOP]
>UniRef100_B7Q9Y0 DNA topoisomerase I, putative (Fragment) n=1 Tax=Ixodes scapularis
RepID=B7Q9Y0_IXOSC
Length = 499
Score = 155 bits (392), Expect = 2e-36
Identities = 68/150 (45%), Positives = 100/150 (66%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG + +GNF++EPP LF GRG+HP G +KRR+ PEDV +N+G A IP P
Sbjct: 351 EYGFCIIDGHRQKIGNFKIEPPGLFRGRGEHPKMGMLKRRVMPEDVIINIGKEAKIPP-P 409
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
GH W ++ H++ V+WL+ W ++I G KY+ L+ S KG D K+E AR+LKS +
Sbjct: 410 PEGHRWKEVRHDNTVSWLSSWTENILGQTKYIMLNPSSKLKGEKDMQKYEMARKLKSKVG 469
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKL 453
IR++Y + W +K +RQRS ALY IDK+
Sbjct: 470 VIREDYMRDWKSKEMRIRQRSVALYFIDKV 499
[228][TOP]
>UniRef100_B3TAG0 Putative eukaryotic DNA topoisomerase I, catalytic core n=1
Tax=uncultured marine crenarchaeote HF4000_APKG8D22
RepID=B3TAG0_9ARCH
Length = 563
Score = 155 bits (391), Expect = 2e-36
Identities = 73/171 (42%), Positives = 110/171 (64%)
Frame = +1
Query: 19 LVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHN 198
++DG+E +GN+ EPP +F+GRG+HP+ G+ K R+ +DVTLNLG A IPE
Sbjct: 135 IIDGKEVEIGNYMAEPPGIFMGRGEHPMRGRYKLRVTAKDVTLNLGKEAKIPEA-----K 189
Query: 199 WGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKE 378
WGKI+H+ W+A W D +T KYVWL+ + K D AK++KA+ L I +++ +
Sbjct: 190 WGKIVHDRNSMWIASWMDILTQKRKYVWLADTAGIKQEMDQAKYDKAKNLSKEIENVKAQ 249
Query: 379 YRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + ++ ++ +TA YLI + ++RVG+EK DEADTVG +LR EH+
Sbjct: 250 IIKDMQSNEQKNKRIATACYLIYRTSMRVGDEKDPDEADTVGATTLRKEHI 300
[229][TOP]
>UniRef100_B3T4E9 Putative eukaryotic DNA topoisomerase I, catalytic core n=1
Tax=uncultured marine crenarchaeote HF4000_ANIW133O4
RepID=B3T4E9_9ARCH
Length = 563
Score = 155 bits (391), Expect = 2e-36
Identities = 73/171 (42%), Positives = 110/171 (64%)
Frame = +1
Query: 19 LVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHN 198
++DG+E +GN+ EPP +F+GRG+HP+ G+ K R+ +DVTLNLG A IPE
Sbjct: 135 IIDGKEVEIGNYMAEPPGIFMGRGEHPMRGRYKLRVTAKDVTLNLGKEAKIPEA-----K 189
Query: 199 WGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIASIRKE 378
WGKI+H+ W+A W D +T KYVWL+ + K D AK++KA+ L I +++ +
Sbjct: 190 WGKIVHDRNSMWIASWMDILTQKRKYVWLADTAGIKQEMDQAKYDKAKNLSKEIENVKAQ 249
Query: 379 YRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
K + ++ ++ +TA YLI + ++RVG+EK DEADTVG +LR EH+
Sbjct: 250 IIKDMQSNEQKNKRIATACYLIYRTSMRVGDEKDPDEADTVGATTLRKEHI 300
[230][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 154 bits (388), Expect = 5e-36
Identities = 85/176 (48%), Positives = 115/176 (65%), Gaps = 4/176 (2%)
Frame = +1
Query: 16 ALVDGRE-ETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPE-DVTLNLGPNAPIPECPVP 189
A+VDG E VGNFRV + +VK+ + + D+T+N+G +APIPE P+P
Sbjct: 338 AVVDGMSREKVGNFRVGTTRVVQRSWRASKDPQVKKNVYSQIDITINIGKDAPIPEPPIP 397
Query: 190 GHNWGKIIHNSCVTWLAGWKDSITGG-YKYVWLSAGSAFKGMSDHAKFEKARQLKSCIAS 366
G W +I H++ VTWLA W D I +KYV+L+A S+ KG K+EK+R+LK I
Sbjct: 398 GERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGKVTREKYEKSRKLKDYIEG 457
Query: 367 IRKE-YRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
IR Y K +A+K + RQ + A YLIDKLALR GNEK +DEADTVGCC+L+VE++
Sbjct: 458 IRAAAYTKDFASKDSKKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 513
[231][TOP]
>UniRef100_A0RU10 DNA topoisomerase IB n=1 Tax=Cenarchaeum symbiosum
RepID=A0RU10_CENSY
Length = 519
Score = 150 bits (378), Expect = 7e-35
Identities = 76/176 (43%), Positives = 109/176 (61%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ +A++DG+E + ++ EPP +F+GRG HPL GK KRRI P+DV LN+G A P
Sbjct: 120 KYGIAVMDGKEVEIASYMAEPPGIFIGRGKHPLRGKWKRRIGPQDVVLNMGTKAKAP--- 176
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCIA 363
PG W KI+H W+A W D++ KYVWL+ + K D +K+EKA L I
Sbjct: 177 -PG-KWKKIVHEKDGIWIAKWTDNLVKKDKYVWLADTAGLKQERDRSKYEKAVALSKKIG 234
Query: 364 SIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
I + K +K ++ + +TA YLI + A+RVG+EK +DEADTVG +LR EH+
Sbjct: 235 EIEAKIVKDMKSKDPKISKIATACYLIYRTAMRVGDEKDKDEADTVGATTLRKEHI 290
[232][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 145 bits (367), Expect = 1e-33
Identities = 73/143 (51%), Positives = 95/143 (66%), Gaps = 1/143 (0%)
Frame = +1
Query: 106 GKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWL 285
G +KRRI PEDV +N ++ IPE P GH W ++ ++ VTWLA W +SI KY+ L
Sbjct: 2 GMLKRRITPEDVVINCSRDSKIPEPPA-GHQWKEVRSDNTVTWLAAWTESIQNSIKYIML 60
Query: 286 SAGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRV 465
+ S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR
Sbjct: 61 NPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRA 120
Query: 466 GNEKAEDE-ADTVGCCSLRVEHL 531
GNEK + E ADTVGCCSLRVEH+
Sbjct: 121 GNEKEDGEAADTVGCCSLRVEHV 143
[233][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 145 bits (366), Expect = 2e-33
Identities = 72/143 (50%), Positives = 95/143 (66%), Gaps = 1/143 (0%)
Frame = +1
Query: 106 GKVKRRIQPEDVTLNLGPNAPIPECPVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWL 285
G +KRRI PEDV +N ++ IPE P GH W ++ ++ VTWLA W +S+ KY+ L
Sbjct: 2 GMLKRRITPEDVVINCSRDSKIPEPPA-GHQWKEVRSDNTVTWLAAWTESVQNSIKYIML 60
Query: 286 SAGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRV 465
+ S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR
Sbjct: 61 NPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRA 120
Query: 466 GNEKAEDE-ADTVGCCSLRVEHL 531
GNEK + E ADTVGCCSLRVEH+
Sbjct: 121 GNEKEDGEAADTVGCCSLRVEHV 143
[234][TOP]
>UniRef100_UPI000179DDCD DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2)
(TOP1mt). n=1 Tax=Bos taurus RepID=UPI000179DDCD
Length = 620
Score = 139 bits (349), Expect = 2e-31
Identities = 72/177 (40%), Positives = 105/177 (59%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
++F +++DG E +G+F+ EP ++ GRGDHP ++KRR+ PEDV +N ++ +PE
Sbjct: 128 QEFGCSILDGHREKIGSFKTEPWSV-RGRGDHPKMERLKRRVLPEDVVINCSRDSTVPEP 186
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P G W ++ + V WLA W +++ KYV L+ G KG D K+E A +LK +
Sbjct: 187 PA-GPQWKEVGCDCTVMWLAAWTENVQNFIKYVTLNPGCKLKGERDWGKYEAAWRLKGAV 245
Query: 361 ASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
I +YR + RQR+ ALY I+KLAL+ GN E+ GCCSLRVEHL
Sbjct: 246 GKICSQYRTAGTSPEMRTRQRAVALYFINKLALQTGN--GEEGGGLGGCCSLRVEHL 300
[235][TOP]
>UniRef100_Q6IQI8 Top1l protein (Fragment) n=1 Tax=Danio rerio RepID=Q6IQI8_DANRE
Length = 469
Score = 135 bits (341), Expect = 1e-30
Identities = 59/141 (41%), Positives = 90/141 (63%)
Frame = +1
Query: 1 RQFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC 180
+++ ++D +E + NFR+EPP LF GRGDHP G +KRRI+PED+ +N ++ P
Sbjct: 329 QEYGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPT- 387
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLKSCI 360
P PG W ++ H++ VTWL W ++I G KY+ L+ S KG D K+E AR+LK C+
Sbjct: 388 PPPGTKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCV 447
Query: 361 ASIRKEYRKGWAAKGKEVRQR 423
IR +YR W +K K+ +++
Sbjct: 448 DRIRSQYRDDWKSKKKKKKKK 468
[236][TOP]
>UniRef100_Q4XMK5 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium chabaudi
RepID=Q4XMK5_PLACH
Length = 429
Score = 120 bits (301), Expect = 6e-26
Identities = 60/117 (51%), Positives = 77/117 (65%), Gaps = 2/117 (1%)
Frame = +1
Query: 7 FTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPEC-- 180
+T ALVD E + + + EPP LF GRG+HP G +K+RI PEDV +N+ +AP P
Sbjct: 313 YTFALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPAPRLYD 372
Query: 181 PVPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKFEKARQLK 351
+ GHNWG I H++ VTWLA +KDSI KY +LSA S FKG D K+E AR+LK
Sbjct: 373 DMCGHNWGDIYHDNKVTWLAYYKDSINDQIKYTFLSAQSKFKGYKDFLKYENARKLK 429
[237][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6JVY3_SCHJY
Length = 654
Score = 116 bits (291), Expect = 9e-25
Identities = 49/91 (53%), Positives = 66/91 (72%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F L+DGR+E VGNFR+EPP LF GRG HP TG +KRR+ PE +T+N+G A +PE P
Sbjct: 363 KFKWCLLDGRKEKVGNFRIEPPGLFRGRGSHPKTGTLKRRVYPEQITINIGKGAKVPE-P 421
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKY 276
+PGH W ++ H+ VTWLA W +++ G KY
Sbjct: 422 LPGHKWAEVRHDDQVTWLAMWHENVNGNVKY 452
[238][TOP]
>UniRef100_B4LSA9 GJ16237 n=1 Tax=Drosophila virilis RepID=B4LSA9_DROVI
Length = 557
Score = 113 bits (283), Expect = 7e-24
Identities = 63/172 (36%), Positives = 97/172 (56%), Gaps = 2/172 (1%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLT-GKVKRRIQPEDVTLNLGPNAPIPECPVPGHN 198
+DG + FR++PP L R + LT G ++ R+ PED+ +N A P P PGH
Sbjct: 183 IDGERHRINQFRIKPPGLCCPRKGYSLTMGMIRPRVLPEDIMINCDEYAE-PPAPPPGHR 241
Query: 199 WGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFK-GMSDHAKFEKARQLKSCIASIRK 375
W +++H+ V+WL W D ++G YV + + + + E AR+L+ + SIR+
Sbjct: 242 WRQVVHDRSVSWLYSWHDLVSGNTYYVRARIDQSKRYRLPLRNQLETARRLQQHLPSIRR 301
Query: 376 EYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
EYR+ W++ VRQRS ALY ID+LA+ + ++ D V C LRVE+L
Sbjct: 302 EYRQLWSSDQWLVRQRSVALYCIDQLAMTC---EDPEQPDKVTLCDLRVENL 350
[239][TOP]
>UniRef100_UPI0001A2BD10 UPI0001A2BD10 related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2BD10
Length = 349
Score = 108 bits (271), Expect = 2e-22
Identities = 48/101 (47%), Positives = 68/101 (67%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
+F L+DG E +GNF++EPP LF GRG+HP G++K+RIQPEDV +N ++ IPE P
Sbjct: 250 EFGYCLLDGHREKIGNFKLEPPGLFRGRGEHPKMGRLKKRIQPEDVAINCSKDSKIPE-P 308
Query: 184 VPGHNWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFK 306
GH W ++ H++ VTWLA W ++I KY+ L+ S K
Sbjct: 309 PAGHKWKRVQHDNTVTWLASWLENIQKRPKYIMLNPSSKLK 349
[240][TOP]
>UniRef100_C3ZV88 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3ZV88_BRAFL
Length = 299
Score = 95.5 bits (236), Expect = 2e-18
Identities = 46/77 (59%), Positives = 56/77 (72%), Gaps = 1/77 (1%)
Frame = +1
Query: 304 KGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAE 483
+G D K+E AR+L C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNEK
Sbjct: 2 QGEKDWMKYETARKLHKCVDRIRAQYREEWKSKEMRIRQRAVALYFIDKLALRAGNEKDS 61
Query: 484 DE-ADTVGCCSLRVEHL 531
DE ADTVGCCSLRVEH+
Sbjct: 62 DEAADTVGCCSLRVEHI 78
[241][TOP]
>UniRef100_Q5BXE0 SJCHGC03473 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BXE0_SCHJA
Length = 238
Score = 94.4 bits (233), Expect = 5e-18
Identities = 48/83 (57%), Positives = 55/83 (66%)
Frame = +1
Query: 283 LSAGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALR 462
L+ S KG D K+E AR L I IR +YR + K +RQR+ ALY IDKLALR
Sbjct: 1 LNPSSRLKGEKDWKKYETARCLHKVIDKIRADYRADFKHKEMRIRQRAVALYFIDKLALR 60
Query: 463 VGNEKAEDEADTVGCCSLRVEHL 531
GNEK EDEADTVGCCSLR EH+
Sbjct: 61 AGNEKDEDEADTVGCCSLRYEHI 83
[242][TOP]
>UniRef100_Q5C1T3 SJCHGC05060 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5C1T3_SCHJA
Length = 330
Score = 91.7 bits (226), Expect = 3e-17
Identities = 37/81 (45%), Positives = 56/81 (69%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECP 183
++ ++DG ++ +GNFR+EPP LF GRG+HP G +K+RI PEDV +N ++ +P P
Sbjct: 250 EYGYCILDGHKQRIGNFRIEPPGLFRGRGNHPKMGMLKKRIMPEDVIINCSKDSKVP-AP 308
Query: 184 VPGHNWGKIIHNSCVTWLAGW 246
GH W ++ H++ VTWLA W
Sbjct: 309 PKGHKWKEVRHDNSVTWLACW 329
[243][TOP]
>UniRef100_B4KJC7 GI24443 n=1 Tax=Drosophila mojavensis RepID=B4KJC7_DROMO
Length = 555
Score = 90.1 bits (222), Expect = 9e-17
Identities = 54/166 (32%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Frame = +1
Query: 19 LVDGREETVGNFRVEPPNLFLGRGDHPLT-GKVKRRIQPEDVTLNLGPNAPIPECPVPGH 195
LVDG + FR+ P L R T G ++ R+ PEDV +N N P P GH
Sbjct: 179 LVDGESRRITQFRISRPGLCCPRHGFSTTMGTIRPRVLPEDVVINCDENEE-PPAPPCGH 237
Query: 196 NWGKIIHNSCVTWLAGWKDSITGGYKYVWLSAGSAFKGMSDHAKF-EKARQLKSCIASIR 372
W ++H+ V W+ W D +TG + + S+ + + AR+L+ + IR
Sbjct: 238 LWAAVVHDRTVRWVYAWNDIVTGCMHHAYPRNESSRRSRPPRRDLLDTARRLQQHLHHIR 297
Query: 373 KEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEADTVGCC 510
EY+ +++ VRQRS ALY ID+LA+ E+ E G C
Sbjct: 298 NEYQTLQSSENWLVRQRSVALYCIDQLAMSCDAEEVPAETTVCGLC 343
[244][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 72.0 bits (175), Expect = 2e-11
Identities = 33/40 (82%), Positives = 36/40 (90%)
Frame = +1
Query: 412 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 2 VRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 41
[245][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 71.6 bits (174), Expect = 3e-11
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 412 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 2 IRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 41
[246][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 71.6 bits (174), Expect = 3e-11
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 412 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 2 IRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI 41
[247][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 70.5 bits (171), Expect = 7e-11
Identities = 31/40 (77%), Positives = 36/40 (90%)
Frame = +1
Query: 412 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL 531
+RQR+ ALY ID+LALR GNEK ED+ADTVGCCSLRVEH+
Sbjct: 2 IRQRAVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHI 41
[248][TOP]
>UniRef100_B3MVN1 GF23753 n=1 Tax=Drosophila ananassae RepID=B3MVN1_DROAN
Length = 240
Score = 63.9 bits (154), Expect = 7e-09
Identities = 35/91 (38%), Positives = 48/91 (52%)
Frame = +1
Query: 22 VDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNLGPNAPIPECPVPGHNW 201
+DG+ V +F + P+L+ G P G VK RIQPEDV +N N P P GH W
Sbjct: 135 IDGKRHRVPHFSFDGPSLYRRSG--PKYGMVKPRIQPEDVNINSQENGA-PGAP-DGHTW 190
Query: 202 GKIIHNSCVTWLAGWKDSITGGYKYVWLSAG 294
+IH+ V WL W D+++G Y + G
Sbjct: 191 KSVIHDRRVDWLWSWTDALSGRVHYQVIQVG 221
[249][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 62.0 bits (149), Expect = 3e-08
Identities = 31/40 (77%), Positives = 33/40 (82%), Gaps = 1/40 (2%)
Frame = +1
Query: 415 RQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHL 531
RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH+
Sbjct: 4 RQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHI 43
[250][TOP]
>UniRef100_UPI000187E0BD hypothetical protein MPER_05582 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187E0BD
Length = 265
Score = 56.2 bits (134), Expect = 1e-06
Identities = 26/50 (52%), Positives = 33/50 (66%)
Frame = +1
Query: 4 QFTVALVDGREETVGNFRVEPPNLFLGRGDHPLTGKVKRRIQPEDVTLNL 153
++T +DGR+E VGNFRVEPP LF GRG+HP G +K P + L L
Sbjct: 207 KYTHCFLDGRKEKVGNFRVEPPGLFRGRGEHPKKGSLKVIGSPSLIALGL 256