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[1][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 196 bits (497), Expect = 1e-48
Identities = 98/169 (57%), Positives = 126/169 (74%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR GNEK EDEADTVGCCSLR EH+ +PP TV FDFLGKDSIRY N V
Sbjct: 403 ATAMYLIDLFALRAGNEKGEDEADTVGCCSLRYEHISLSPPNTVVFDFLGKDSIRYYNEV 462
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL++F R+ K D +F RL+ + LN++L LMPGLSAKVFRT NAS T++E
Sbjct: 463 QVDPQVFKNLKIFKRSPKTEGDMLFDRLNTSKLNNHLTSLMPGLSAKVFRTHNASYTMSE 522
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ P + +++DKV YN+ N++VA LCNH RT+ H QM+++E +
Sbjct: 523 QLKNTPKDASISDKVLAYNRANRMVAILCNHQRTISKTHSAQMERIEDK 571
[2][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 193 bits (490), Expect = 7e-48
Identities = 103/168 (61%), Positives = 119/168 (70%), Gaps = 2/168 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVE 184
TA+YLID ALR GNEK EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY N VE
Sbjct: 456 TAMYLIDVFALRAGNEKGEDEADTVGCCSLRYEHVTLKPPRTVVFDFLGKDSIRYYNEVE 515
Query: 185 VDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
VD VF NL++F R K+ D IF RLS SLN YL LM GLSAKVFRT+NAS T+AE
Sbjct: 516 VDPQVFKNLKIFKRPPKKEGDLIFDRLSTNSLNKYLTSLMDGLSAKVFRTYNASYTMAEE 575
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ P T+ DK+ FYN+ N+ VA LCNH R++ H QM++ R
Sbjct: 576 LKKMPKNLTLADKILFYNRANRTVAILCNHQRSVTKNHDVQMERFAER 623
[3][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 192 bits (487), Expect = 2e-47
Identities = 95/170 (55%), Positives = 121/170 (71%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLID+LALR GNEK EDEADTVGCCSL+VEH+ P ++ FDFLGKDSIRY N V
Sbjct: 218 AVATYLIDRLALRAGNEKDEDEADTVGCCSLKVEHVSLIAPKSLQFDFLGKDSIRYFNTV 277
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EVD+ V+ + F + K+ D++F RL T LN +LK +MPGL+AKVFRT+NAS+TL
Sbjct: 278 EVDERVYKAIGQFKKGKKGGDDLFERLDTTKLNLHLKGIMPGLTAKVFRTYNASITLDTL 337
Query: 362 LQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
LQ GET + +A Y + NK VA LCNH R++ GH QM++LE + E
Sbjct: 338 LQDTRGETTIEIIADYQRANKEVAILCNHQRSVSKGHSAQMERLELKMQE 387
[4][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 190 bits (483), Expect = 5e-47
Identities = 94/170 (55%), Positives = 120/170 (70%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLID+LALR GNEK EDEADTVGCCSL+VEH+ P ++ FDFLGKDSIRY N V
Sbjct: 348 AVATYLIDRLALRAGNEKDEDEADTVGCCSLKVEHVTLVAPKSLQFDFLGKDSIRYFNTV 407
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EVD+ V+ + F + K+ D++F RL T LN +LK +MP L+AKVFRT+NAS+TL
Sbjct: 408 EVDERVYKAIGQFKKGKKEGDDLFERLDTTKLNLHLKGIMPSLTAKVFRTYNASITLDNL 467
Query: 362 LQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
LQ GET + +A Y + NK VA LCNH R++ GH QM++LE + E
Sbjct: 468 LQDTTGETTIEIIADYQRANKQVAILCNHQRSVSKGHSAQMERLEGKMQE 517
[5][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 190 bits (482), Expect = 6e-47
Identities = 99/174 (56%), Positives = 124/174 (71%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ P V FDFLGKDSIR
Sbjct: 680 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVELYPELNGKENVVVFDFLGKDSIR 739
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NL LF NKQP D++F RL+ T LN +L +LM GL+AKVFRT+NAS
Sbjct: 740 YYNEVPVEKRVFKNLLLFKENKQPQDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASW 799
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL E L+ +P +TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 800 TLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKAK 853
[6][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 188 bits (477), Expect = 2e-46
Identities = 100/183 (54%), Positives = 126/183 (68%), Gaps = 10/183 (5%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 732 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIALHEKKDGKEYVVVFDFLGKDSIR 791
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF +LQLF NK P D +F RL+ T +N +L +LM GL+AKVFRT+NAS
Sbjct: 792 YYNEVPVEKRVFKSLQLFMENKSPGDELFDRLNTTVMNKHLNELMDGLTAKVFRTYNASW 851
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAE 511
TL + L+ DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ + + E
Sbjct: 852 TLQQQLEELTDPNSTVAEKILSYNRANRAVAILCNHQRSVPKSHEKSMENLKAKIDAKRE 911
Query: 512 AVA 520
A+A
Sbjct: 912 AIA 914
[7][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 187 bits (474), Expect = 5e-46
Identities = 98/174 (56%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ V FDFLGKDSIR
Sbjct: 683 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIDLHKELNGKENVVVFDFLGKDSIR 742
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+P D++F RL+ + LN++L++LM GL+AKVFRTFNAS
Sbjct: 743 YYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVLNEHLRELMEGLTAKVFRTFNASF 802
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L+ DP TV +K+ YN+ N+ VA LCNH R +P H+ M L+ +
Sbjct: 803 TLQNQLRELTDPDMTVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMSNLKEK 856
[8][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 186 bits (473), Expect = 7e-46
Identities = 99/175 (56%), Positives = 121/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 459 AVALYFIDKLALRAGNEKDEGETADTVGCCSLRVEHIKLHPQLDGQDYVVEFDFLGKDSI 518
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQ D++F RL+ + LN YL++LM GL+AKVFRT+NAS
Sbjct: 519 RYYNKIPVEKRVFKNLQLFLENKQSEDDLFDRLNTSILNKYLQELMDGLTAKVFRTYNAS 578
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L PGE + +K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 579 ITLQQQLNELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQTK 633
[9][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 186 bits (473), Expect = 7e-46
Identities = 97/174 (55%), Positives = 124/174 (71%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 6 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIELHEQKDDKEFVVVFDFLGKDSIR 65
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF NK P+D++F RL+ +N +L +LM GL+AKVFRTFNAS
Sbjct: 66 YYNEVPVEKRVFKNLQLFMENKAPADDLFDRLNTQIMNKHLNELMDGLTAKVFRTFNASY 125
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L + +T+++K+ YN+ N+ VA LCNH R++P GH+ M+KL+ +
Sbjct: 126 TLQQQLDELTNADDTLSEKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLKEK 179
[10][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 186 bits (472), Expect = 9e-46
Identities = 96/169 (56%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + V
Sbjct: 538 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEV 597
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 598 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 657
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+G T+ +K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 658 LLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGDR 706
[11][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 186 bits (472), Expect = 9e-46
Identities = 96/169 (56%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + V
Sbjct: 543 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEV 602
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 603 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 662
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+G T+ +K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 663 LLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGDR 711
[12][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 186 bits (472), Expect = 9e-46
Identities = 98/169 (57%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLIDK ALR GNEK EDEADTVGCCSL+ E++ PP TV FDFLGKDSIR+ + V
Sbjct: 498 ATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENISLRPPNTVIFDFLGKDSIRFYDEV 557
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T A
Sbjct: 558 EVDPQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFAT 617
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ E TV +KV YN N+ VA LCNH RT+ +GH QM+KL R
Sbjct: 618 LLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGDR 666
[13][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 186 bits (471), Expect = 1e-45
Identities = 97/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 6 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIELHEQKDDKEYVVVFDFLGKDSIR 65
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF NK P D++F RL+ +N +L +LM GL+AKVFRT+NAS
Sbjct: 66 YYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASW 125
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH+ M+KL+ +
Sbjct: 126 TLQQQLDELTNDDDTVAEKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLKEK 179
[14][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 186 bits (471), Expect = 1e-45
Identities = 98/174 (56%), Positives = 120/174 (68%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDFLGKDSIR
Sbjct: 678 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIELHKELNGKENVVVFDFLGKDSIR 737
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+P D++F RL+ + LN++L+ LM GL+AKVFRTFNAS
Sbjct: 738 YYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVLNEHLRDLMDGLTAKVFRTFNASF 797
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R +P H M L+ +
Sbjct: 798 TLQNQLAELTDPNMTVPEKMLAYNRANRAVAILCNHQRAVPKTHDKSMSNLKEK 851
[15][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 186 bits (471), Expect = 1e-45
Identities = 98/169 (57%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLIDK ALR GNEK EDEADTVGCCSL+ E++ PP TV FDFLGKDSIR+ + V
Sbjct: 502 ATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENVSLRPPNTVIFDFLGKDSIRFYDEV 561
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T A
Sbjct: 562 EVDPQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFAT 621
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ E TV +KV YN N+ VA LCNH RT+ +GH QM+KL R
Sbjct: 622 LLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGDR 670
[16][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 185 bits (470), Expect = 1e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 756 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNNKENVVVFDFPGKDSIR 815
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 816 YYNEVEVEKRVFKNLELFMENKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 875
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP +V +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 876 TLQNQLDLLTDPNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 929
[17][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 184 bits (468), Expect = 3e-45
Identities = 97/174 (55%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 702 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIR 761
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF NK PSD++F RL+ T +N +L +LM GL+AKVFRT+NAS
Sbjct: 762 YYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASW 821
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L +P +T +K+ YN+ N+ VA LCNH R++P H M+ L+ +
Sbjct: 822 TLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAK 875
[18][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 184 bits (467), Expect = 3e-45
Identities = 99/180 (55%), Positives = 126/180 (70%), Gaps = 11/180 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
S ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDFLGKDSIR
Sbjct: 460 SVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIQLHEEFNDKEYVVVFDFLGKDSIR 519
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NL++F NK+ SD++F RL+ + LN +L +LM GL+AKVFRTFNAS
Sbjct: 520 YYNEVPVEKRVFKNLKIFMENKKGSDDLFDRLNTSILNQHLHELMDGLTAKVFRTFNASW 579
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM----QKLETRRA 508
TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+ M +K++T+RA
Sbjct: 580 TLQQQLEKLTDPDVSVAEKILQYNRANRAVAILCNHQRAIPKTHEKSMGNLKEKIQTKRA 639
[19][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 184 bits (467), Expect = 3e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 767 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNDKENVVVFDFPGKDSIR 826
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 827 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASK 886
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 887 TLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 940
[20][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 184 bits (467), Expect = 3e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 755 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNDKENVVVFDFPGKDSIR 814
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 815 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASK 874
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 875 TLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 928
[21][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 184 bits (467), Expect = 3e-45
Identities = 94/167 (56%), Positives = 121/167 (72%), Gaps = 2/167 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TALY IDKLALR G EK AE++ADTVGCCSLRVEHL+ P + FDFLGKDSIRY+N
Sbjct: 2128 ATALYFIDKLALRAGGEKDAEEQADTVGCCSLRVEHLELLPGDELVFDFLGKDSIRYQNQ 2187
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
V+VD V+ N+ F ++K+P D +F RL LN+YL+ LM GL+AKVFRT+NAS+TL +
Sbjct: 2188 VKVDHQVWKNVGHFKKSKEPGDELFDRLRTQQLNEYLQSLMDGLTAKVFRTYNASITLQD 2247
Query: 359 CLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
L+ P G TV +K+ Y + N+ VA LCNH R P H QM++L+
Sbjct: 2248 QLKSTPAGGTVEEKLLAYQRANRAVAILCNHQRAAPKTHDEQMERLD 2294
[22][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 184 bits (467), Expect = 3e-45
Identities = 94/169 (55%), Positives = 120/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TALY ID+LALR GNEK EDEADTVGCCSLR EH+ +PP T+ FDFLGKDS+R+ V
Sbjct: 521 ATALYFIDRLALRAGNEKGEDEADTVGCCSLRYEHVTLSPPNTIIFDFLGKDSMRFHQEV 580
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF N++LF + K+ D+IF RL+ T LN +L +MPGL+AKVFRT+NAS T E
Sbjct: 581 EVDPQVFKNIKLFKADPKKKGDDIFDRLTTTLLNKHLNSMMPGLTAKVFRTYNASWTFQE 640
Query: 359 CLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ P TV +K+A YN N+ VA LCNH +++ G +G K E +
Sbjct: 641 QLKNTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAEDK 689
[23][TOP]
>UniRef100_C4Q6C8 DNA topoisomerase type I, putative n=2 Tax=Schistosoma mansoni
RepID=C4Q6C8_SCHMA
Length = 587
Score = 184 bits (466), Expect = 4e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK EDEADTVGCCSLR EH+K P V FDFLGKDSIR
Sbjct: 397 AVALYFIDKLALRAGNEKDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIR 456
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y+NAV V K VF N++LF +NK+ +D++F RL+ T LN YL++LM GL+AKVFRT+NAS
Sbjct: 457 YQNAVSVPKRVFKNVKLFLKNKKENDDLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASR 516
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL E L+ +P + K+ YN+ N+ VA LCNH R++P M+ L+ +
Sbjct: 517 TLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAKSMENLQKK 570
[24][TOP]
>UniRef100_C4Q6C7 DNA topoisomerase type I, putative n=1 Tax=Schistosoma mansoni
RepID=C4Q6C7_SCHMA
Length = 652
Score = 184 bits (466), Expect = 4e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK EDEADTVGCCSLR EH+K P V FDFLGKDSIR
Sbjct: 397 AVALYFIDKLALRAGNEKDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIR 456
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y+NAV V K VF N++LF +NK+ +D++F RL+ T LN YL++LM GL+AKVFRT+NAS
Sbjct: 457 YQNAVSVPKRVFKNVKLFLKNKKENDDLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASR 516
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL E L+ +P + K+ YN+ N+ VA LCNH R++P M+ L+ +
Sbjct: 517 TLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAKSMENLQKK 570
[25][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 184 bits (466), Expect = 4e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 717 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 776
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 777 YYNEVEVEKRVFKNLELFMEHKKDGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASK 836
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 837 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 890
[26][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 183 bits (465), Expect = 6e-45
Identities = 99/175 (56%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K V FDFLGKDSI
Sbjct: 304 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHSKLDGQEHVVEFDFLGKDSI 363
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF +NK P D++F RLS LN +L++LM GL+AKVFRT+NAS
Sbjct: 364 RYYNKVSVEKPVFKNLQLFMKNKDPGDDLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNAS 423
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P + MQ L+T+
Sbjct: 424 ITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQTK 478
[27][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 183 bits (465), Expect = 6e-45
Identities = 99/175 (56%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K V FDFLGKDSI
Sbjct: 304 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHSKLDGQEHVVEFDFLGKDSI 363
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF +NK P D++F RLS LN +L++LM GL+AKVFRT+NAS
Sbjct: 364 RYYNKVSVEKPVFKNLQLFMKNKDPGDDLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNAS 423
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P + MQ L+T+
Sbjct: 424 ITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQTK 478
[28][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 183 bits (465), Expect = 6e-45
Identities = 94/169 (55%), Positives = 120/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TALY ID+LALR GNEK EDEADTVGCCSLR EH+ +PP T+ FDFLGKDS+R+ V
Sbjct: 484 ATALYFIDRLALRAGNEKGEDEADTVGCCSLRYEHVTLSPPNTIIFDFLGKDSMRFHQEV 543
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF N++LF + K+ D+IF RL+ T LN +L +MPGL+AKVFRT+NAS T E
Sbjct: 544 EVDPQVFKNIKLFKADPKKKGDDIFDRLTTTLLNKHLNGMMPGLTAKVFRTYNASWTFQE 603
Query: 359 CLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ P TV +K+A YN N+ VA LCNH +++ G +G K E +
Sbjct: 604 QLKNTPTNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAEDK 652
[29][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 183 bits (465), Expect = 6e-45
Identities = 96/169 (56%), Positives = 120/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + V
Sbjct: 534 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKFEHVTLKPPNTVVFDFLGKDSIRYYDEV 593
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 594 EVDPQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 653
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +KV YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 654 LLKKMSATGTIPEKVKQYNDANREVAILCNHKRTVAASHANQMEKLGDR 702
[30][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 183 bits (464), Expect = 7e-45
Identities = 91/168 (54%), Positives = 120/168 (71%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N V
Sbjct: 642 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 701
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
+V+ AVF +Q F K+ S+++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL +
Sbjct: 702 QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 761
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + G V +KV Y NK VA +CNH RT+ H QM +L +
Sbjct: 762 LSKETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEK 809
[31][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 183 bits (464), Expect = 7e-45
Identities = 96/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFT-----PPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 710 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHRELNGKENVVVFDFPGKDSIR 769
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 770 YYNEVEVEKRVFKNLELFMENKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASK 829
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L D TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 830 TLQDQLDKLTDGDATVAEKLLAYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 883
[32][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 182 bits (463), Expect = 1e-44
Identities = 95/170 (55%), Positives = 118/170 (69%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V
Sbjct: 302 AVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDV 361
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ LQ F R K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 362 AVLPEVYALLQRFTRRKSPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRW 421
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ DP + DK+A++NK N VA LCNH +++ K QM +L T+
Sbjct: 422 FKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[33][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 182 bits (463), Expect = 1e-44
Identities = 95/170 (55%), Positives = 118/170 (69%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V
Sbjct: 302 AVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDV 361
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ LQ F R K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 362 AVLPEVYALLQRFTRRKSPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRW 421
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ DP + DK+A++NK N VA LCNH +++ K QM +L T+
Sbjct: 422 FKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[34][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 182 bits (463), Expect = 1e-44
Identities = 95/169 (56%), Positives = 119/169 (70%), Gaps = 3/169 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVE 184
TA YLIDKLALRVGNEK EDEADTVGCCSLRVEH+K V+FDFLGKDS+RY N V+
Sbjct: 300 TATYLIDKLALRVGNEKDEDEADTVGCCSLRVEHIKLKEDDVVAFDFLGKDSMRYNNEVK 359
Query: 185 VDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 364
+ ++ NL+LF + KQP DN+F +SV LND+LK+ M GL+AKVFRT+NAS TL + L
Sbjct: 360 LAHQIWKNLKLFIKGKQPEDNLFSDISVDDLNDFLKKQMEGLTAKVFRTYNASFTLQQQL 419
Query: 365 QGD---PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
G +V KV FY+ NK VA LCNH +T+ + +K+ T+
Sbjct: 420 DLGGKLDGHSVQQKVDFYDNANKQVAILCNHQKTISKQFELTKKKINTK 468
[35][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 182 bits (462), Expect = 1e-44
Identities = 95/174 (54%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 649 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHKEKDGKEYVVVFDFLGKDSIR 708
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF +K P D++F RL+ +N +L +LM GL+AKVFRT+NAS
Sbjct: 709 YYNEVPVEKRVFKNLQLFMEHKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASW 768
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L + ++V +K+ YN+ N+ VA LCNH R++P GH+ M+KL+ +
Sbjct: 769 TLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLKEK 822
[36][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 182 bits (462), Expect = 1e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ A+Y IDKLALR GNEK +D+ADTVGCCSLR EH+ V FDFLGKDSIR
Sbjct: 701 AVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIR 760
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+P D++F RL+ + +N+YLK LM GL+AKVFRTFNAS
Sbjct: 761 YYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASY 820
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+ M L+ +
Sbjct: 821 TLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEK 874
[37][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 182 bits (462), Expect = 1e-44
Identities = 96/174 (55%), Positives = 120/174 (68%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 776 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNCKENVVVFDFPGKDSIR 835
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 836 YYNEVEVEKRVFKNLELFMENKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 895
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L D TV +K+ YN+ N+ VA LCNH R++P GH+ M L+ +
Sbjct: 896 TLQSQLDLLTDGSATVAEKLLAYNRANRAVAILCNHQRSVPKGHQKSMDNLKEK 949
[38][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 182 bits (461), Expect = 2e-44
Identities = 96/174 (55%), Positives = 120/174 (68%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGKDSIR
Sbjct: 6 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDDKEYVVVFDFLGKDSIR 65
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF NK D++F RL+ +N +L +LM GL+AKVFRT+NAS
Sbjct: 66 YYNEVPVEKRVFKNLQLFMENKSAGDDLFDRLNTQIMNKHLNELMEGLTAKVFRTYNASW 125
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH M+KL+ +
Sbjct: 126 TLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKGHAKSMEKLKEK 179
[39][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 107 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 166
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 167 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 226
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 227 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 281
[40][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 308 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 367
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 368 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 427
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 428 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 481
[41][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 701 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 760
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 761 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 820
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 821 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 874
[42][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 307 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 366
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 367 YYNEVEVEKRVFKNLELFMEHKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 426
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 427 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 480
[43][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 758 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 817
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 818 YYNEVEVEKRVFKNLELFMENKKDGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASK 877
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L D +V +K+ YN+ N+ VA LCNH R++P GH+ M+ L+ +
Sbjct: 878 TLQNQLDLLTDSNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEK 931
[44][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 697 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 756
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 757 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 816
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 817 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 870
[45][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 181 bits (460), Expect = 2e-44
Identities = 98/175 (56%), Positives = 118/175 (67%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSI 163
S ALY ID+LALR G+EK E E ADTVGCCSLR EH+K V FDFLGKDSI
Sbjct: 271 SAALYFIDRLALRAGHEKEEGESADTVGCCSLRYEHIKLHDQLEDKMNVVEFDFLGKDSI 330
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NL+LFC+NK+ D++F RLS TSLN YL +LM GL+AKVFRT+NAS
Sbjct: 331 RYVNQVPVEKQVYKNLKLFCKNKKKGDDLFDRLSTTSLNKYLSELMEGLTAKVFRTYNAS 390
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL E L DP ++ DK+ YN+ N+ VA LCNH RT+ QM L +
Sbjct: 391 YTLQEQLHQVIDPKMSIEDKILIYNRSNRAVAILCNHQRTVSKTFDKQMSNLREK 445
[46][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 696 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 755
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 756 YYNEVEVEKRVFKNLELFMEHKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 815
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 816 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 869
[47][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 181 bits (460), Expect = 2e-44
Identities = 94/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIR 166
+ ALY ID+LALR GNEK ED+ADTVGCCSLRVEH+ K FDFLGKDSIR
Sbjct: 6 AVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHISLHEQKDGKEYVTVFDFLGKDSIR 65
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N V V+K VF NLQLF NK P D++F RL+ +N +L +LM GL+AKVFRT+NAS
Sbjct: 66 YYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTQIMNKHLNELMDGLTAKVFRTYNASW 125
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL + L + +T+ +K+ YN+ N+ VA LCNH R++P GH+ M+KL+ +
Sbjct: 126 TLQQQLDELTNADDTLAEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEK 179
[48][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 214 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 273
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 274 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 333
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 334 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 388
[49][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 214 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 273
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 274 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 333
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 334 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 388
[50][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 107 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 166
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 167 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 226
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 227 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 281
[51][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 214 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 273
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 274 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 333
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 334 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 388
[52][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 181 bits (460), Expect = 2e-44
Identities = 95/174 (54%), Positives = 121/174 (69%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 699 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 758
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 759 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 818
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 819 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 872
[53][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 181 bits (460), Expect = 2e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 312 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 371
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 372 RYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 431
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 432 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 486
[54][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 181 bits (459), Expect = 3e-44
Identities = 94/176 (53%), Positives = 121/176 (68%), Gaps = 1/176 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N V
Sbjct: 623 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 682
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ AVF +Q F K+ S ++F L + LN +LK+LMPGL+AKVFRT+NAS+TL +
Sbjct: 683 EVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 742
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWV 526
L + G V +KV Y NK VA +CNH RT+ H QM +L + E A V
Sbjct: 743 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVV 798
[55][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 181 bits (459), Expect = 3e-44
Identities = 89/168 (52%), Positives = 120/168 (71%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP + DF+GKDSIRY+N V
Sbjct: 641 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEV 700
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
+V+ AVF +Q F K+ S+++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL +
Sbjct: 701 QVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + G V +KV Y + NK VA +CNH RT+ H QM +L +
Sbjct: 761 LSKETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSAQMSRLNEK 808
[56][TOP]
>UniRef100_Q5BXE0 SJCHGC03473 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BXE0_SCHJA
Length = 238
Score = 181 bits (459), Expect = 3e-44
Identities = 94/174 (54%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK EDEADTVGCCSLR EH+K P V FDFLGKDSIR
Sbjct: 48 AVALYFIDKLALRAGNEKDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIR 107
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y+N+V V K VF N++LF +NK+ +D++F RL+ + LN YL++LM GL+AKVFRT+NAS
Sbjct: 108 YQNSVSVPKRVFKNVKLFLKNKKENDDLFDRLNTSVLNQYLRELMDGLTAKVFRTYNASR 167
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL E L+ +P + K+ YN+ N+ VA LCNH R++P M+ L+ +
Sbjct: 168 TLEEQLERLTNPDDPPHAKLLAYNRANRAVAVLCNHQRSVPKSFAKSMENLQKK 221
[57][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 181 bits (459), Expect = 3e-44
Identities = 95/174 (54%), Positives = 120/174 (68%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 308 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 367
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL LN++LK+LM GL+AKVFRT+NAS
Sbjct: 368 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLKTQVLNEHLKELMEGLTAKVFRTYNASK 427
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 428 TLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK 481
[58][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 181 bits (459), Expect = 3e-44
Identities = 98/176 (55%), Positives = 117/176 (66%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLID ALR G EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY V
Sbjct: 371 AVATYLIDVFALRAGGEKSEDEADTVGCCSLRYEHISLKPPNTVVFDFLGKDSIRYYQEV 430
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL +F R K+P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ +
Sbjct: 431 EVDKQVFKNLSIFKRPPKEPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQD 490
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L P E +VT+K+ YN N+ VA LCNH RT+ H MQK T + E W
Sbjct: 491 QLDLIPNEGSVTEKMVRYNAANRAVAILCNHQRTVGRSHAQSMQK-ATEKIEEYQW 545
[59][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 181 bits (458), Expect = 4e-44
Identities = 96/175 (54%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V FDFLGKDSI
Sbjct: 373 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIQLHPQLDGQEHVVEFDFLGKDSI 432
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF +NK P++++F LS T LN +L++LM GL+AKVFRT+NAS
Sbjct: 433 RYYNKVSVEKPVFKNLQLFMKNKDPTEDLFDHLSTTFLNKHLQRLMDGLTAKVFRTYNAS 492
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +P + + K+ YN+ N+ VA LCNH R++P MQ L+ +
Sbjct: 493 ITLQEQLKALTNPEDNIAGKLLSYNRANRAVAILCNHQRSIPKTFAKSMQVLQEK 547
[60][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 181 bits (458), Expect = 4e-44
Identities = 93/169 (55%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP+TV FDFLGKDSIR+ + V
Sbjct: 549 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPSTVIFDFLGKDSIRFYDEV 608
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 609 EVDPQVFKNLKIFKKAPKREGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 668
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ ++ +K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 669 LLKDLKSTGSIAEKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDR 717
[61][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 181 bits (458), Expect = 4e-44
Identities = 97/175 (55%), Positives = 122/175 (69%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK + EA DTVGCCSLRVEH++ P V FDFLGKD I
Sbjct: 312 AVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCI 371
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF +K P DN+F RL+ TSLN +L++LM GL+AKVFRT+NAS
Sbjct: 372 RYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNAS 431
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+T+
Sbjct: 432 ITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTK 486
[62][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 180 bits (457), Expect = 5e-44
Identities = 99/176 (56%), Positives = 119/176 (67%), Gaps = 8/176 (4%)
Frame = +2
Query: 8 ALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRY 169
A+Y IDKLALR G+EK E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY
Sbjct: 427 AMYFIDKLALRAGHEKEEGESADTVGCCSLRVEHITLHPEKDGQENVVEFDFLGKDSIRY 486
Query: 170 ENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVT 349
N+V V+K VF NLQLF + KQ D++F RLS TSLN +L +LMPGLSAKVFRT+NAS+T
Sbjct: 487 TNSVPVEKRVFKNLQLFMQGKQAGDDLFDRLSTTSLNKFLGELMPGLSAKVFRTYNASIT 546
Query: 350 LAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + L + G +VT K YN+ N+ VA LCNH R P QM+ + + E
Sbjct: 547 LQQQLNELTEEGASVTAKFLQYNRANRAVAILCNHQRAAPKTFDKQMENIVNKLKE 602
[63][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 180 bits (456), Expect = 6e-44
Identities = 99/175 (56%), Positives = 118/175 (67%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 214 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPELDGDKYVVEFDFLGKDSI 273
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQ D++F RLS LN +L+ LM GL+AKVFRT+NAS
Sbjct: 274 RYYNKVPVEKQVFKNLQLFMENKQEGDDLFDRLSTPLLNKHLQSLMEGLTAKVFRTYNAS 333
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P M L+++
Sbjct: 334 ITLQQQLQELTDPEESMPSKILSYNRANRAVAILCNHQRAPPKTFDQSMANLKSK 388
[64][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 180 bits (456), Expect = 6e-44
Identities = 92/171 (53%), Positives = 123/171 (71%), Gaps = 5/171 (2%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVE 184
TA YLIDKLALRVGNEK+E+EADTVGCCSLRVEH++ T + FDFLGKDS+RY+N V+
Sbjct: 412 TATYLIDKLALRVGNEKSEEEADTVGCCSLRVEHIQVIEDTQIGFDFLGKDSMRYQNTVK 471
Query: 185 VDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 364
V + V+ N+Q F +NK+P D++F R+ +SLN+YLK M GL+AKVFRT+NAS TL + L
Sbjct: 472 VTEIVWKNMQSFIKNKKPGDDLFDRIDASSLNEYLKSQMEGLTAKVFRTYNASHTLQKEL 531
Query: 365 -----QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+G + DK+ FY++ N+ VA LCNH +T+ + K+E R
Sbjct: 532 DKADEEGLDKMDLKDKLNFYDEANRNVAILCNHQKTVGKNFDVMVGKMEQR 582
[65][TOP]
>UniRef100_A4HB62 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania braziliensis
RepID=A4HB62_LEIBR
Length = 637
Score = 180 bits (456), Expect = 6e-44
Identities = 93/170 (54%), Positives = 117/170 (68%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH++ V FDFLGKDSIRY+N V
Sbjct: 302 AVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMSDNIVRFDFLGKDSIRYQNDV 361
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ LQ F R K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 362 AVLPEVYALLQRFTRRKSPGTDIFDQLNPTQLNDHLKSFMNGLSAKVFRTYNASITLDRW 421
Query: 362 LQGDPGE---TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ P + ++ DK+A++NK N VA LCNH + + K QM +L T+
Sbjct: 422 FKEKPVDSKWSIADKLAYFNKANTEVAILCNHQKAISKNFKLQMMQLTTK 471
[66][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 179 bits (455), Expect = 8e-44
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 486 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSI 545
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 546 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 605
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ +P + + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 606 ITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 660
[67][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 179 bits (455), Expect = 8e-44
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 477 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSI 536
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 537 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 596
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ +P + + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 597 ITLQQQLKELTNPDDNIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 651
[68][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 179 bits (455), Expect = 8e-44
Identities = 94/170 (55%), Positives = 117/170 (68%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V
Sbjct: 302 AVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDV 361
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ LQ F K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 362 AVLPEVYALLQRFTCRKSPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRW 421
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ DP + DK+A++NK N VA LCNH +++ K QM +L T+
Sbjct: 422 FKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQLTTK 471
[69][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 179 bits (455), Expect = 8e-44
Identities = 97/176 (55%), Positives = 116/176 (65%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLID ALR G EKA+DEADTVGCCSLR EH+ PP TV FDFLGKDSIRY V
Sbjct: 424 AVATYLIDVFALRAGGEKADDEADTVGCCSLRYEHVTLRPPNTVVFDFLGKDSIRYYQEV 483
Query: 182 EVDKAVFFNLQLFCRNKQ-PSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F R P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ +
Sbjct: 484 EVDAQVFKNLKIFKRPPSGPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQD 543
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L P E TV +K+ YN N+ VA LCNH RT+ GH +QK T R E + W
Sbjct: 544 QLDLIPNEGTVAEKILRYNAANRTVAILCNHQRTVTKGHASSVQK-ATERIEELEW 598
[70][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 179 bits (454), Expect = 1e-43
Identities = 97/175 (55%), Positives = 118/175 (67%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 627 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPEMDGQEYVVEFDFLGKDSI 686
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 687 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 746
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+T+
Sbjct: 747 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK 801
[71][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 179 bits (454), Expect = 1e-43
Identities = 94/174 (54%), Positives = 122/174 (70%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N V
Sbjct: 592 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 651
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V K VF +QLF K+ D++F +L + LN +LK+LMPGL+AKVFRT+NASVTL +
Sbjct: 652 AVYKPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASVTLEQQ 711
Query: 362 L-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA 520
L + G + +KVA YN NK VA +CNH R++ H Q+ KL + E A
Sbjct: 712 LTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNEKIDELKA 765
[72][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 179 bits (454), Expect = 1e-43
Identities = 95/169 (56%), Positives = 120/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + V
Sbjct: 543 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEV 602
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A
Sbjct: 603 EVDPQVFKNLKIFKKAPKKDGDEIFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMAT 662
Query: 359 CL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L Q + T+ +KV YN N+ VA LCNH RT+ +GH QM+KL R
Sbjct: 663 LLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGER 711
[73][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 179 bits (454), Expect = 1e-43
Identities = 97/174 (55%), Positives = 122/174 (70%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLID+LALR GNEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y
Sbjct: 550 ATAMYLIDRLALRAGNEKDTENEADTVGCCSLKYEHITLEPPNKVTFDFLGKDSIPYRET 609
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
V+ VF NL+LF + K D++F RL+ T LN +L MPGL+AKVFRT+NAS T++
Sbjct: 610 AHVEPQVFKNLKLFKKAPKTKGDDLFDRLTTTQLNKHLTNYMPGLTAKVFRTYNASFTMS 669
Query: 356 ECLQG---DPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
E L+G DP +V +KV YN N+ VA LCNH RT+ +GH+ QMQKL R
Sbjct: 670 ELLKGLSKDPRSRGSVAEKVKLYNDCNREVAILCNHKRTVGAGHEQQMQKLGDR 723
[74][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 179 bits (454), Expect = 1e-43
Identities = 95/172 (55%), Positives = 116/172 (67%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 384 AVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEV 443
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL +F R KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ +
Sbjct: 444 EVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQD 503
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P + +V +K+ YN N+ VA LCNH RT+ GH ++K R E
Sbjct: 504 QLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQE 555
[75][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 179 bits (454), Expect = 1e-43
Identities = 95/169 (56%), Positives = 120/169 (71%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + V
Sbjct: 543 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEV 602
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A
Sbjct: 603 EVDPQVFKNLKIFKKAPKKDGDEIFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMAT 662
Query: 359 CL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L Q + T+ +KV YN N+ VA LCNH RT+ +GH QM+KL R
Sbjct: 663 LLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGER 711
[76][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 179 bits (454), Expect = 1e-43
Identities = 95/172 (55%), Positives = 116/172 (67%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 408 AVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEV 467
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL +F R KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ +
Sbjct: 468 EVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQD 527
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P + +V +K+ YN N+ VA LCNH RT+ GH ++K R E
Sbjct: 528 QLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQE 579
[77][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 179 bits (454), Expect = 1e-43
Identities = 90/174 (51%), Positives = 113/174 (64%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+Y IDKLALR GNEK EDEADTVGCCSLR EH+ PP + FDFLGKDSIRY V
Sbjct: 520 ATAMYFIDKLALRAGNEKGEDEADTVGCCSLRCEHVTLRPPNEIVFDFLGKDSIRYFKEV 579
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
VD VF N+++F K+ DN+F R++ LN +L M GL+AKVFRT+NAS T
Sbjct: 580 PVDAQVFKNIRIFKEGKELEDNLFDRVTTAGLNKHLTSYMKGLTAKVFRTYNASSTFQRL 639
Query: 362 LQGD--PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAV 517
L + T+ +K+ YNK N++VA LCNH R P H M+K+ + A V
Sbjct: 640 LDEEDLTNATIQEKINAYNKANRMVAILCNHQRAAPKTHDQSMEKMRYKAAPVV 693
[78][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 179 bits (454), Expect = 1e-43
Identities = 95/172 (55%), Positives = 116/172 (67%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 408 AVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEV 467
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL +F R KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ +
Sbjct: 468 EVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQD 527
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P + +V +K+ YN N+ VA LCNH RT+ GH ++K R E
Sbjct: 528 QLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQE 579
[79][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 179 bits (453), Expect = 1e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ V FDFLGKDSI
Sbjct: 400 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIQLHREMDGQEHVVEFDFLGKDSI 459
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NL+LF +NK P D++F RLS TSLN +L+ LM GL+AKVFRT+NAS
Sbjct: 460 RYYNKVPVEKQVYKNLRLFMQNKDPGDDLFDRLSTTSLNKHLQDLMDGLTAKVFRTYNAS 519
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ D + V K+ YN+ N+ VA LCNH R P + MQ L+ +
Sbjct: 520 ITLQEQLKALTDAEDNVAAKILSYNRANRAVAILCNHQRATPKTFEKSMQNLQAK 574
[80][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 179 bits (453), Expect = 1e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 462 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSI 521
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 522 RYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 581
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 582 ITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 636
[81][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 179 bits (453), Expect = 1e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 462 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSI 521
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 522 RYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 581
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 582 ITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 636
[82][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 179 bits (453), Expect = 1e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 466 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSI 525
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 526 RYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 585
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 586 ITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 640
[83][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 179 bits (453), Expect = 1e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 464 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSI 523
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 524 RYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 583
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 584 ITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 638
[84][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 179 bits (453), Expect = 1e-43
Identities = 90/171 (52%), Positives = 120/171 (70%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSIRYEN V
Sbjct: 575 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTV 634
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ ++ F K+P+D++F L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 635 EVELPVYKAIRQFQVAKKPTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEK 694
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + V +K YN+ NK VA +CNH RT+ H QM +L + E
Sbjct: 695 LYEETEDGDVAEKFVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKLEE 745
[85][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 179 bits (453), Expect = 1e-43
Identities = 93/172 (54%), Positives = 116/172 (67%), Gaps = 7/172 (4%)
Frame = +2
Query: 8 ALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYE 172
ALY IDKLALR G+EK +D ADTVGCCSLRVEH+K V FDFLGKDS+RY
Sbjct: 216 ALYFIDKLALRAGHEKDDDTADTVGCCSLRVEHIKLHEEWEDKECVVEFDFLGKDSVRYR 275
Query: 173 NAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
N V ++K F N++LF KQ D++F RL+ TS+N YL +LM GLSAKVFRTFNAS+TL
Sbjct: 276 NFVPIEKRAFKNMKLFMEGKQEGDDLFDRLTTTSVNKYLSELMEGLSAKVFRTFNASLTL 335
Query: 353 AECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ LQ +P + V K+ YN+ N+ VA LCNH RT P + M L+ +
Sbjct: 336 QDQLQKLTNPEDNVNAKILSYNRANRAVAILCNHQRTAPKTFEKSMSNLQLK 387
[86][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 179 bits (453), Expect = 1e-43
Identities = 93/169 (55%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIR+ + V
Sbjct: 547 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEV 606
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A
Sbjct: 607 EVDPQVFKNLKIFKKPPKREGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMAT 666
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 667 LLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDR 715
[87][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 179 bits (453), Expect = 1e-43
Identities = 93/169 (55%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIR+ + V
Sbjct: 547 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEV 606
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A
Sbjct: 607 EVDPQVFKNLKIFKKPPKREGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMAT 666
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 667 LLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDR 715
[88][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 178 bits (452), Expect = 2e-43
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 284 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSI 343
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 344 RYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 403
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 404 ITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 458
[89][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 178 bits (452), Expect = 2e-43
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 516 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSI 575
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 576 RYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 635
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 636 ITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 690
[90][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 178 bits (452), Expect = 2e-43
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 538 RYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 598 ITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 652
[91][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 178 bits (452), Expect = 2e-43
Identities = 96/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 538 RYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 598 ITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 652
[92][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 178 bits (452), Expect = 2e-43
Identities = 94/176 (53%), Positives = 120/176 (68%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A Y ID ALR G EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY V
Sbjct: 383 AVATYFIDVFALRAGGEKSEDEADTVGCCSLRFEHVTLKPPNTVIFDFLGKDSIRYHQEV 442
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EV+K VF NL++F R K+ D++F RL + LN YL+ MPGL+AKVFRT+NAS T+ +
Sbjct: 443 EVEKQVFKNLKIFKRPPKKDGDDLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQD 502
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L P E TV +K+ YN N+ VA LCNH R++ GH ++K+ ++ E + W
Sbjct: 503 QLDLIPNEGTVAEKLLKYNAANRAVAILCNHQRSVTKGHAQSVEKM-NQKIEELLW 557
[93][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 178 bits (452), Expect = 2e-43
Identities = 93/172 (54%), Positives = 118/172 (68%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
++A+YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 418 ASAIYLIDVFALRAGGEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEV 477
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F + KQP D++F R++ T LN L+ M GL+AKVFRT+NAS T+ +
Sbjct: 478 EVDKQVFKNLRIFKKAPKQPGDDLFDRINPTMLNKQLQNYMKGLTAKVFRTYNASKTMQD 537
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P E TV +KV +N N+ VA LCNH RT+ GH +QK+ + E
Sbjct: 538 QLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKGHGSSVQKINDKLKE 589
[94][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 178 bits (451), Expect = 2e-43
Identities = 95/170 (55%), Positives = 118/170 (69%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y ID+LALRVGNEK EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V
Sbjct: 617 AVAMY-IDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDV 675
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ LQ F R K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 676 AVLPEVYALLQRFTRRKSPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRW 735
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ DP + DK+A++NK N VA LCNH +++ K QM +L T+
Sbjct: 736 FKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQLTTK 785
[95][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 178 bits (451), Expect = 2e-43
Identities = 92/172 (53%), Positives = 119/172 (69%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLID ALR G EK EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 404 ATATYLIDVFALRAGGEKGEDEADTVGCCSLRYEHVTLRPPNTVIFDFLGKDSIRFYQEV 463
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD+ VF NL++F + KQP D++F R++ +LN +L+ M GL+AKVFRT+NAS T+ +
Sbjct: 464 EVDRQVFKNLRIFKKEPKQPGDDLFDRITPATLNKHLQAYMKGLTAKVFRTYNASKTMQD 523
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ P E TV +KV YN N+ VA LCNH RT+ H+ + K++ + E
Sbjct: 524 QMDLIPNEGTVAEKVMKYNAANRTVAILCNHQRTVSKAHQNSVGKIQEKIKE 575
[96][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 178 bits (451), Expect = 2e-43
Identities = 97/175 (55%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 476 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 535
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 536 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 595
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+T+
Sbjct: 596 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK 650
[97][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 177 bits (450), Expect = 3e-43
Identities = 97/175 (55%), Positives = 118/175 (67%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 214 AVALYFIDKLALRAGNEKEEGESADTVGCCSLRVEHIKLYPELDGEKHVVEFDFLGKDSI 273
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+ D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 274 RYYNKVPVEKQVFKNLQLFMENKEEGDDLFDRLNTPLLNKHLQSLMEGLTAKVFRTYNAS 333
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P M L+++
Sbjct: 334 ITLQQQLQELTDPEESIPAKILSYNRANRAVAILCNHQRAPPKTFDQSMANLKSK 388
[98][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 177 bits (450), Expect = 3e-43
Identities = 89/165 (53%), Positives = 117/165 (70%), Gaps = 1/165 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP+ + FDFLGKDSIRY+N V
Sbjct: 609 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSILKFDFLGKDSIRYQNEV 668
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ +Q F K+ D++F +L + LN +LK LMPGL+AKVFRT+NAS+TL E
Sbjct: 669 EVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEM 728
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
L + G V +K+ Y NK VA +CNH RT+ H QM +L
Sbjct: 729 LSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMTRL 773
[99][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 177 bits (449), Expect = 4e-43
Identities = 95/175 (54%), Positives = 120/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 481 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEFVVEFDFLGKDSI 540
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 541 RYYNKIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 600
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ +++ K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 601 ITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 655
[100][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 177 bits (449), Expect = 4e-43
Identities = 91/165 (55%), Positives = 115/165 (69%), Gaps = 1/165 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE++ PP ++ FDFLGKDSIRYE V
Sbjct: 573 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTV 632
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ ++ F K SD++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 633 EVELPVYKAIEQFRVGKSGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEM 692
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
L D E V KV Y NK VA +CNH RT+ H QM +L
Sbjct: 693 LNKDTKEGDVAQKVVVYQHANKEVAIICNHQRTISKSHTAQMTRL 737
[101][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 177 bits (449), Expect = 4e-43
Identities = 92/169 (54%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ +H+ PP TV FDFLGKDSIR+ + V
Sbjct: 543 ATAIYLIDQFALRAGNEKGEDEADTVGCCSLKFQHITLRPPETVIFDFLGKDSIRFYDEV 602
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL+LF + K D+IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 603 KVDPQVFKNLKLFKKEPKTTGDDIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMAR 662
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ TV +KV YN N+ VA LCNH RT+ + H ++K+ R
Sbjct: 663 LLKEMKATGTVQEKVKAYNDANREVAILCNHKRTVAASHATSIEKMNER 711
[102][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus caballus
RepID=UPI0001797824
Length = 765
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 476 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 535
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 536 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 595
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 596 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 650
[103][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 176 bits (447), Expect = 7e-43
Identities = 97/175 (55%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKDSI
Sbjct: 492 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHTEMDGQEYVVEFDFLGKDSI 551
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 552 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 611
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
VTL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+T+
Sbjct: 612 VTLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK 666
[104][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 538 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 598 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 652
[105][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 715 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 774
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 775 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 834
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 835 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 889
[106][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 463 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 522
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 523 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 582
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 583 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 637
[107][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 480 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 539
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 540 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 599
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 600 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 654
[108][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 176 bits (447), Expect = 7e-43
Identities = 88/168 (52%), Positives = 117/168 (69%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ PP + DF+GKDSIRY+N V
Sbjct: 641 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEV 700
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
+V+ AVF +Q F K+ ++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL +
Sbjct: 701 QVEPAVFKAIQQFRSGKEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + G V +KV Y NK VA +CNH RT+ H QM +L +
Sbjct: 761 LSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEK 808
[109][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 271 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 330
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 331 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 390
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 391 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 445
[110][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 176 bits (447), Expect = 7e-43
Identities = 97/175 (55%), Positives = 116/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 476 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 535
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT NAS
Sbjct: 536 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTHNAS 595
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+T+
Sbjct: 596 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK 650
[111][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 176 bits (447), Expect = 7e-43
Identities = 92/174 (52%), Positives = 118/174 (67%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK EDEADTVGCCSLR EHL PP V FDFLGKDSIR+ V
Sbjct: 489 ATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHLTLKPPNQVIFDFLGKDSIRFYQEV 548
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F ++ K+P D+IF R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 549 EVDKQVFKNLRIFKKDPKRPGDDIFDRINPSMVNKQLQNYMKGLTAKVFRTYNASKTMQD 608
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAV 517
L P E T +KV +N N+ VA LCNH RT+ H +QK+ + E +
Sbjct: 609 QLDLIPNEGTAAEKVVKFNAANRTVAILCNHQRTVSKNHGNSVQKINDKLRELI 662
[112][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 176 bits (447), Expect = 7e-43
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 538 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 598 ITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 652
[113][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 176 bits (446), Expect = 9e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ V FDFLGKDSI
Sbjct: 151 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIQLYEEQDGMEFVVKFDFLGKDSI 210
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RYEN+V V+K VF NL+LF NK+ DN+F RL+ + LN YL++LM GL+AKVFRT+NAS
Sbjct: 211 RYENSVPVEKRVFKNLKLFTENKKGEDNLFDRLNTSILNKYLQELMEGLTAKVFRTYNAS 270
Query: 344 VTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L D ++VT K+ YN+ N+ VA LCNH R P QM+ L+ +
Sbjct: 271 STLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQEK 325
[114][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 176 bits (446), Expect = 9e-43
Identities = 97/175 (55%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ V FDFLGKDSI
Sbjct: 590 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIQLYEEQDGMEFVVKFDFLGKDSI 649
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RYEN+V V+K VF NL+LF NK+ DN+F RL+ + LN YL++LM GL+AKVFRT+NAS
Sbjct: 650 RYENSVPVEKRVFKNLKLFTENKKGEDNLFDRLNTSILNKYLQELMEGLTAKVFRTYNAS 709
Query: 344 VTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L D ++VT K+ YN+ N+ VA LCNH R P QM+ L+ +
Sbjct: 710 STLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQEK 764
[115][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 176 bits (446), Expect = 9e-43
Identities = 86/168 (51%), Positives = 119/168 (70%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N V
Sbjct: 636 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCMPPNKIQFDFLGKDSIRYFNTV 695
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV++ V+ ++ F K+P + +F ++ T LN +LK LMPGL+AKVFRT+NAS+TL
Sbjct: 696 EVEELVYKAIEGFRAGKKPGEGLFDKIDTTRLNAHLKDLMPGLTAKVFRTYNASITLDGI 755
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + + T+ +K+A Y + NK VA +CNH R++ H+ QM KL +
Sbjct: 756 LHEETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHESQMIKLNEK 803
[116][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 176 bits (446), Expect = 9e-43
Identities = 95/176 (53%), Positives = 116/176 (65%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A Y ID ALR G EKA+DEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 395 AVACYFIDVFALRAGGEKADDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEV 454
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EV K VF NL +F + K+P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ +
Sbjct: 455 EVTKQVFKNLTIFKKPPKKPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQD 514
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L P E TV +K+ YN N+ VA LCNH RT+ GH +QK T R E + W
Sbjct: 515 QLDLIPNEGTVAEKMLKYNAANRTVAILCNHQRTVTKGHAASVQK-ATERIEELEW 569
[117][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 176 bits (445), Expect = 1e-42
Identities = 96/175 (54%), Positives = 119/175 (68%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEHL P V FDFLGKDSI
Sbjct: 469 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHLTLHPEMDGQEFVVEFDFLGKDSI 528
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF +K+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 529 RYYNKVPVEKRVFKNLQLFMEDKEPEDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 588
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L + + V K+ YN+ N+ VA LCNH R P + MQ L+T+
Sbjct: 589 ITLQQQLNELTNSEDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK 643
[118][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 176 bits (445), Expect = 1e-42
Identities = 88/174 (50%), Positives = 120/174 (68%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK EDEA+TVGCC+L+V+++ PP + FDFLGKDSIRY N V
Sbjct: 631 AVATYLIDKLALRAGNEKDEDEAETVGCCTLKVDNVTCVPPNKLQFDFLGKDSIRYFNTV 690
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ ++ F K+P ++F +L T LN +LK LMPGL+AKVFRT+NAS+TL +
Sbjct: 691 EVELLVYKAIEEFRAGKKPGQDLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDI 750
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA 520
L + + T+ +K+A Y + NK VA +CNH R++ H QM +L + E A
Sbjct: 751 LHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEKIDELKA 804
[119][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 176 bits (445), Expect = 1e-42
Identities = 88/174 (50%), Positives = 120/174 (68%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK EDEA+TVGCC+L+V+++ PP + FDFLGKDSIRY N V
Sbjct: 631 AVATYLIDKLALRAGNEKDEDEAETVGCCTLKVDNVTCVPPNKLQFDFLGKDSIRYFNTV 690
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ ++ F K+P ++F +L T LN +LK LMPGL+AKVFRT+NAS+TL +
Sbjct: 691 EVELLVYKAIEEFRAGKKPGQDLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDI 750
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA 520
L + + T+ +K+A Y + NK VA +CNH R++ H QM +L + E A
Sbjct: 751 LHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEKIDELKA 804
[120][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 176 bits (445), Expect = 1e-42
Identities = 96/181 (53%), Positives = 121/181 (66%), Gaps = 11/181 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+LALRVGNEK ED ADTVGCCSLRVEH+ P +V+ DFLGKDS+RY N V
Sbjct: 669 ATAIYLIDRLALRVGNEKDEDTADTVGCCSLRVEHVTLKEPASVTLDFLGKDSMRYHNTV 728
Query: 182 EVDKAVFFNLQLFCRN-------KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNA 340
+VD VF NL F K+P +++F +L+ +SLN YLK M LSAKVFRT+NA
Sbjct: 729 DVDPRVFKNLSEFMYKGGNKKAPKKPENDLFDQLTTSSLNKYLKGFMENLSAKVFRTYNA 788
Query: 341 SVTLAECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRA 508
S+TL + L P T +KV FYN+ N+ VA LCNH R+L H M K++ + A
Sbjct: 789 SLTLEKELAKMPESLIKATADEKVLFYNRCNREVAILCNHQRSLSKTHTETMGKIDEKIA 848
Query: 509 E 511
E
Sbjct: 849 E 849
[121][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 176 bits (445), Expect = 1e-42
Identities = 94/166 (56%), Positives = 115/166 (69%), Gaps = 2/166 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLID ALR G EKAEDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY V
Sbjct: 402 AVATYLIDVFALRAGGEKAEDEADTVGCCSLRYEHVTLKPPNTVVFDFLGKDSIRYYQEV 461
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
V + VF NL+LF ++ KQP D++F RL+ LN +L+ +PGLSAKVFRT+NAS T+ +
Sbjct: 462 NVHEKVFKNLRLFKKSPKQPGDDLFDRLTPNILNKHLQNYLPGLSAKVFRTYNASKTMQD 521
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
L P E +V +KV YN N+ VA LCNH RT P H +Q++
Sbjct: 522 QLDLIPNEGSVGEKVVKYNAANREVAILCNHQRTKPKSHDMGVQRI 567
[122][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 176 bits (445), Expect = 1e-42
Identities = 97/182 (53%), Positives = 118/182 (64%), Gaps = 15/182 (8%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT------------TVSFD 142
+TALY IDKLALR GNEK DEA DTVGCCSLRVEH+K V FD
Sbjct: 446 ATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFD 505
Query: 143 FLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKV 322
FLGKDSIRY N V V+K V+ NL++F K PSD++F RL +LND+L+ LM GL+ KV
Sbjct: 506 FLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKV 565
Query: 323 FRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
FRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G MQKLE
Sbjct: 566 FRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLE 625
Query: 497 TR 502
+
Sbjct: 626 QK 627
[123][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 176 bits (445), Expect = 1e-42
Identities = 97/182 (53%), Positives = 118/182 (64%), Gaps = 15/182 (8%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT------------TVSFD 142
+TALY IDKLALR GNEK DEA DTVGCCSLRVEH+K V FD
Sbjct: 518 ATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFD 577
Query: 143 FLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKV 322
FLGKDSIRY N V V+K V+ NL++F K PSD++F RL +LND+L+ LM GL+ KV
Sbjct: 578 FLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKV 637
Query: 323 FRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
FRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G MQKLE
Sbjct: 638 FRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLE 697
Query: 497 TR 502
+
Sbjct: 698 QK 699
[124][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 175 bits (444), Expect = 2e-42
Identities = 99/182 (54%), Positives = 124/182 (68%), Gaps = 12/182 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGKDSI
Sbjct: 7 AVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSI 66
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY+N V V+K VF NLQ F +K P D++F L+ +SLN +L+ LM GL+AKVFRT+NAS
Sbjct: 67 RYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNAS 126
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRR 505
VTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ K+ET++
Sbjct: 127 VTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKK 186
Query: 506 AE 511
A+
Sbjct: 187 AQ 188
[125][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 175 bits (444), Expect = 2e-42
Identities = 99/182 (54%), Positives = 124/182 (68%), Gaps = 12/182 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGKDSI
Sbjct: 304 AVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSI 363
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY+N V V+K VF NLQ F +K P D++F L+ +SLN +L+ LM GL+AKVFRT+NAS
Sbjct: 364 RYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNAS 423
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRR 505
VTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ K+ET++
Sbjct: 424 VTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKK 483
Query: 506 AE 511
A+
Sbjct: 484 AQ 485
[126][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 175 bits (444), Expect = 2e-42
Identities = 89/171 (52%), Positives = 119/171 (69%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSIRYEN V
Sbjct: 592 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTV 651
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K+ +D++F L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 652 EVELPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEK 711
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + V +K+ YN+ NK VA +CNH RT+ H QM +L + E
Sbjct: 712 LYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKIEE 762
[127][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 175 bits (444), Expect = 2e-42
Identities = 90/167 (53%), Positives = 113/167 (67%), Gaps = 3/167 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y IDKLALRVGNEK DEADTVGCCSLRVEH++ P V FDFLGKDSIRYEN
Sbjct: 305 AVAMYFIDKLALRVGNEKGSDEADTVGCCSLRVEHIELKPDYVVKFDFLGKDSIRYENEA 364
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ L+ F + K+ D+IF ++ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 365 VVLPRVYELLRRFTKGKKTGDDIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRW 424
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
+ P +V DK+A++NK N VA LCNH +++ H M +L
Sbjct: 425 FKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHHNLMHQL 471
[128][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 175 bits (444), Expect = 2e-42
Identities = 90/167 (53%), Positives = 113/167 (67%), Gaps = 3/167 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+Y IDKLALRVGNEK DEADTVGCCSLRVEH++ P V FDFLGKDSIRYEN
Sbjct: 305 AVAMYFIDKLALRVGNEKGSDEADTVGCCSLRVEHIELKPDHVVKFDFLGKDSIRYENEA 364
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ L+ F + K+ D+IF ++ T LND+LK M GLSAKVFRT+NAS+TL
Sbjct: 365 VVLPRVYELLRRFTKGKKTGDDIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRW 424
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
+ P +V DK+A++NK N VA LCNH +++ H M +L
Sbjct: 425 FKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHHNLMHQL 471
[129][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 175 bits (444), Expect = 2e-42
Identities = 94/171 (54%), Positives = 122/171 (71%), Gaps = 4/171 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLID+ ALR GNEK AE+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ +
Sbjct: 526 ATAMYLIDRFALRAGNEKNAEEEAETVGCCSLKFEHVTLKEPNTVVFDFLGKDSIRFFDE 585
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
V++ VF NL++F + K D+IF RL+ T LN +LK M GL+AKVFRT+NAS T++
Sbjct: 586 FTVERQVFKNLKIFKKPPKGEGDDIFDRLTTTQLNKHLKSYMDGLTAKVFRTYNASFTMS 645
Query: 356 ECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
LQ P E T+ +KV YN N+ VA LCNH RT+ +GH+ QM+KL R
Sbjct: 646 RLLQELPVEKATIAEKVKLYNDCNRKVAILCNHKRTVGAGHQAQMEKLGDR 696
[130][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 175 bits (444), Expect = 2e-42
Identities = 99/182 (54%), Positives = 124/182 (68%), Gaps = 12/182 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGKDSI
Sbjct: 305 AVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSI 364
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY+N V V+K VF NLQ F +K P D++F L+ +SLN +L+ LM GL+AKVFRT+NAS
Sbjct: 365 RYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNAS 424
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRR 505
VTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ K+ET++
Sbjct: 425 VTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKK 484
Query: 506 AE 511
A+
Sbjct: 485 AQ 486
[131][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 175 bits (443), Expect = 2e-42
Identities = 91/170 (53%), Positives = 119/170 (70%), Gaps = 3/170 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP TV FDFLGKDSIR+ + V
Sbjct: 501 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNTVVFDFLGKDSIRFYDEV 560
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+
Sbjct: 561 QVDLQVFKNLKIFKKAPKKNGDEIFDRLTTSALNKHLANYMPGLTAKVFRTYNASYTMGC 620
Query: 359 CL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L G T+ +KV YN N+ VA LCNH RT+ +GH M+K+ R
Sbjct: 621 VLNEMNASGGTIAEKVKAYNDANRKVAILCNHKRTVTAGHANAMEKMGER 670
[132][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 175 bits (443), Expect = 2e-42
Identities = 91/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 636 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 695
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 696 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 755
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +V +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 756 LLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSER 804
[133][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 175 bits (443), Expect = 2e-42
Identities = 91/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 524 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 583
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 584 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMAT 643
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +V +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 644 LLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSER 692
[134][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 174 bits (441), Expect = 3e-42
Identities = 96/175 (54%), Positives = 117/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGKDSI
Sbjct: 366 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIQLYPEADGCQHVVELDFLGKDSI 425
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K V+ NLQLF NK D++F RL+ TSLN +L+ LM GL+AKVFRT+NAS
Sbjct: 426 RYYNRVPVEKPVYKNLQLFMENKSRGDDLFDRLTTTSLNKHLQDLMDGLTAKVFRTYNAS 485
Query: 344 VTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
VTL E L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+ +
Sbjct: 486 VTLQEQLRALTRAEDSVAAKILSYNRANRAVAILCNHQRATPKTFEKSMQNLQLK 540
[135][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 174 bits (441), Expect = 3e-42
Identities = 96/175 (54%), Positives = 116/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDF GKDSI
Sbjct: 469 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSI 528
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 529 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 588
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E V K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 589 ITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 643
[136][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 174 bits (441), Expect = 3e-42
Identities = 84/168 (50%), Positives = 119/168 (70%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N V
Sbjct: 289 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTV 348
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV++ V+ ++ F K+P ++F ++ + LN +LK LMPGL+AKVFRT+NAS+TL
Sbjct: 349 EVEELVYKAIEGFRAGKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGI 408
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + + TV +K+A Y + NK VA +CNH R++ H+ QM ++ +
Sbjct: 409 LHEETEDGTVLEKIAVYQRANKEVAIICNHQRSVSKSHESQMTRMNEK 456
[137][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 174 bits (441), Expect = 3e-42
Identities = 90/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 510 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEV 569
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL++F + K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+AE
Sbjct: 570 DVDPQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASHTMAE 629
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ + +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 630 LLKDMKATGNIAEKVKAYNDANRRVAILCNHKRTVGASHANQMEKMSER 678
[138][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 174 bits (441), Expect = 3e-42
Identities = 96/175 (54%), Positives = 116/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDF GKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 538 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E V K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 598 ITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 652
[139][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 174 bits (441), Expect = 3e-42
Identities = 96/175 (54%), Positives = 116/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDF GKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 538 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E V K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 598 ITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 652
[140][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 174 bits (440), Expect = 4e-42
Identities = 95/174 (54%), Positives = 115/174 (66%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 460 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSI 519
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 520 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 579
Query: 344 VTLAECLQ-GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + + E + K+ YN+ N+ VA LCNH R P + M L+T+
Sbjct: 580 ITLQQQVSFFTADENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK 633
[141][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 174 bits (440), Expect = 4e-42
Identities = 88/171 (51%), Positives = 117/171 (68%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N V
Sbjct: 226 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTV 285
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E
Sbjct: 286 EVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEM 345
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + VT K+ Y K NK VA +CNH RT+ H Q++KL R E
Sbjct: 346 LSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEE 396
[142][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 174 bits (440), Expect = 4e-42
Identities = 88/171 (51%), Positives = 117/171 (68%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N V
Sbjct: 108 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTV 167
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E
Sbjct: 168 EVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEM 227
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + VT K+ Y K NK VA +CNH RT+ H Q++KL R E
Sbjct: 228 LSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEE 278
[143][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 174 bits (440), Expect = 4e-42
Identities = 89/169 (52%), Positives = 118/169 (69%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ +H+ PP TV FDFLGKDSIR+ + V
Sbjct: 525 ATAIYLIDQFALRAGNEKGEDEADTVGCCSLKFQHITLRPPETVIFDFLGKDSIRFYDEV 584
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL++F + K D+IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A
Sbjct: 585 KVDAQVFKNLKIFKKEPKTVGDDIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMAR 644
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +KV YN N+ VA LCNH RT+ + H + K+ +
Sbjct: 645 LLKSLKATGTIQEKVKAYNDANREVAILCNHKRTVAATHGASIDKMNEK 693
[144][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 174 bits (440), Expect = 4e-42
Identities = 89/176 (50%), Positives = 118/176 (67%), Gaps = 6/176 (3%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ P + FDFLGKDSIRY+N V
Sbjct: 478 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVETKRPNILKFDFLGKDSIRYQNEV 537
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ VF ++ F K+ D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 538 EVEPRVFSAIEQFRSGKEGGDDLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEM 597
Query: 362 L------QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ + G V +KV Y NK VA +CNH RT+ H QM +L + E
Sbjct: 598 VRCKLLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEE 653
[145][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 174 bits (440), Expect = 4e-42
Identities = 88/171 (51%), Positives = 117/171 (68%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N V
Sbjct: 628 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTV 687
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E
Sbjct: 688 EVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEM 747
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + VT K+ Y K NK VA +CNH RT+ H Q++KL R E
Sbjct: 748 LSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEE 798
[146][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 174 bits (440), Expect = 4e-42
Identities = 97/182 (53%), Positives = 124/182 (68%), Gaps = 12/182 (6%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGKDSI
Sbjct: 305 AVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHVRLHTPADGQEHVVELDFLGKDSI 364
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY+N V V+K VF NLQ F +K P D++F L+ +SLN +L+ LM GL+AKVFRT+NAS
Sbjct: 365 RYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNAS 424
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRR 505
+TL E L+ +++T KV YN+ N+ VA LCNH R +P + MQ K+ET++
Sbjct: 425 ITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQKKIETKK 484
Query: 506 AE 511
A+
Sbjct: 485 AQ 486
[147][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 173 bits (439), Expect = 6e-42
Identities = 91/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 509 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 568
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E
Sbjct: 569 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSE 628
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 629 LLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAAHAHQMEKMSER 677
[148][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 173 bits (439), Expect = 6e-42
Identities = 93/174 (53%), Positives = 118/174 (67%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID LALR G EK +DEADTVGCCSLR EH+ +PP V FDFLGKDSIRY V
Sbjct: 402 ATAMYLIDVLALRAGGEKGDDEADTVGCCSLRYEHITLSPPNIVEFDFLGKDSIRYHQEV 461
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EV VF NL++F + K+ D+IF RL + LN +L+ MPGL+AKVFRT+NAS T+ +
Sbjct: 462 EVSPQVFKNLRIFKKAPKKVGDDIFDRLDPSVLNKHLQNYMPGLTAKVFRTYNASKTMDD 521
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAV 517
L P E TV +K+ +N N+ VA LCNH +T+ H + K+E R E V
Sbjct: 522 QLALIPNEGTVAEKLVKFNAANRAVAILCNHQKTVSKTHGESVGKIEDRINEVV 575
[149][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 173 bits (439), Expect = 6e-42
Identities = 91/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 509 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 568
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E
Sbjct: 569 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSE 628
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 629 LLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAAHAHQMEKMSER 677
[150][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 173 bits (438), Expect = 8e-42
Identities = 93/168 (55%), Positives = 119/168 (70%), Gaps = 4/168 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLIDK ALR GNEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N
Sbjct: 508 ATAMYLIDKFALRAGNEKDTENEAETVGCCSLKYEHVTLREPNTVIFDFLGKDSIRFYNE 567
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
VD+ VF NL++F + K+ D+IF RL+ T LN +L MPGL+AKVFRT+NAS T++
Sbjct: 568 FTVDRQVFKNLKMFKKPPKEDGDDIFDRLTTTQLNKHLSSYMPGLTAKVFRTYNASYTMS 627
Query: 356 ECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
+ LQ TV +KV YN N+ VA LCNH RT+ + H+ QM+KL
Sbjct: 628 KLLQELKVTNATVHEKVKLYNDCNRQVAILCNHKRTVGASHEQQMKKL 675
[151][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 172 bits (437), Expect = 1e-41
Identities = 87/171 (50%), Positives = 114/171 (66%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE++ PP + FDFLGKDSIRY N V
Sbjct: 598 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSIRYFNTV 657
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 658 EVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEM 717
Query: 362 LQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + G +K+ Y NK VA +CNH R++ H QM +L + E
Sbjct: 718 LNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRE 768
[152][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 172 bits (437), Expect = 1e-41
Identities = 87/171 (50%), Positives = 114/171 (66%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE++ PP + FDFLGKDSIRY N V
Sbjct: 504 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSIRYFNTV 563
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 564 EVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEM 623
Query: 362 LQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + G +K+ Y NK VA +CNH R++ H QM +L + E
Sbjct: 624 LNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRE 674
[153][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 172 bits (437), Expect = 1e-41
Identities = 93/174 (53%), Positives = 118/174 (67%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIR 166
+ ALY IDKLALRVGNEK +D+ADTVGCCSLRVEH++ V+FDFLGKDSIR
Sbjct: 339 AVALYFIDKLALRVGNEKEKDQADTVGCCSLRVEHVQLHRRLMDKEYVVAFDFLGKDSIR 398
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y VEV+ VF NL+LF ++K S +F L+ LND+LK LM GL+ KVFRT+NAS+
Sbjct: 399 YYKTVEVEPRVFNNLKLFVKDKGKSYYVFDCLNAHELNDHLKNLMIGLTTKVFRTYNASL 458
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
TL L D TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L +
Sbjct: 459 TLQNQLDELTDEEATVAEKLLVYNRANRAVAILCNHQRSIPKGHQQIMENLRKK 512
[154][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 172 bits (437), Expect = 1e-41
Identities = 94/175 (53%), Positives = 115/175 (65%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK DEA DTVGCCSLR EH++ V FDFLGKDSI
Sbjct: 472 AVALYFIDKLALRAGNEKDVDEAADTVGCCSLRCEHIQLHEKLDDNDYVVEFDFLGKDSI 531
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NL+LF NK SD++F RL SLN YL+ LMPGL+AKVFRT+NAS
Sbjct: 532 RYYNKVPVEKRVFKNLKLFMENKSGSDDLFDRLDTASLNKYLQSLMPGLTAKVFRTYNAS 591
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L T + + YN+ N+ VA LCNH R +P H+ M+ L+ +
Sbjct: 592 ITLQQQLDKLTKDDSTAPELLLCYNRANRQVAILCNHQRAVPKSHEKSMENLKAK 646
[155][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 172 bits (436), Expect = 1e-41
Identities = 86/168 (51%), Positives = 115/168 (68%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE++ P + F+FLGKDSI+YEN V
Sbjct: 602 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTRETPNKLKFNFLGKDSIKYENTV 661
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F ++K P D++F +L LN +LK+LMPGL+AKVFRTFNAS+TL +
Sbjct: 662 EVELPVYNAILKFQKDKGPGDDLFDKLDTNKLNAHLKELMPGLTAKVFRTFNASITLDDK 721
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L D + +K+ Y NK VA +CNH R++ H QM KL +
Sbjct: 722 LNKDTKDGDAAEKIVVYQHANKQVAIICNHQRSVSKSHSAQMTKLNEK 769
[156][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 172 bits (436), Expect = 1e-41
Identities = 89/166 (53%), Positives = 117/166 (70%), Gaps = 2/166 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENA 178
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ P + + FDFLGKDSIRYEN
Sbjct: 605 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPGSFNLKFDFLGKDSIRYENT 664
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
VEV V+ + F + K+ +D++F +L T LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 665 VEVKPEVYEAIGTFQKGKKQTDDLFDKLDTTKLNAHLKELMPGLTAKVFRTYNASITLDE 724
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 493
L + + V +KV Y + NK VA +CNH RT+ H QM KL
Sbjct: 725 KLYEETEDGDVAEKVVIYQRANKEVAIICNHQRTISKSHGAQMSKL 770
[157][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 172 bits (436), Expect = 1e-41
Identities = 94/178 (52%), Positives = 121/178 (67%), Gaps = 6/178 (3%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
TA+YLID+LALRVGNEK E+EADTVGCCSLRVEH+ F ++ DFLGKDSIRY N V
Sbjct: 355 TAVYLIDRLALRVGNEKNTEEEADTVGCCSLRVEHMTFEADNKITLDFLGKDSIRYLNTV 414
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL-AE 358
+VD V+ NL+ C+ ++P D IF + + +NDY KQ M LSAKVFRT+NAS+TL E
Sbjct: 415 QVDPLVYKNLKTLCKARKPEDMIF-SIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQE 473
Query: 359 CLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA 520
+ DP E ++ V FYN N+ VA LCNH R P H+ M++L+ + A+ A
Sbjct: 474 LCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQHEAGMERLKKKLADQEA 531
[158][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 172 bits (436), Expect = 1e-41
Identities = 94/178 (52%), Positives = 121/178 (67%), Gaps = 6/178 (3%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
TA+YLID+LALRVGNEK E+EADTVGCCSLRVEH+ F ++ DFLGKDSIRY N V
Sbjct: 355 TAVYLIDRLALRVGNEKNTEEEADTVGCCSLRVEHMTFEADNKITLDFLGKDSIRYLNTV 414
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL-AE 358
+VD V+ NL+ C+ ++P D IF + + +NDY KQ M LSAKVFRT+NAS+TL E
Sbjct: 415 QVDPLVYKNLKALCKARKPEDMIF-SIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQE 473
Query: 359 CLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA 520
+ DP E ++ V FYN N+ VA LCNH R P H+ M++L+ + A+ A
Sbjct: 474 LCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQHEAGMERLKKKLADQEA 531
[159][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 172 bits (436), Expect = 1e-41
Identities = 91/171 (53%), Positives = 122/171 (71%), Gaps = 4/171 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLID+ ALR GNEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N
Sbjct: 541 ATAMYLIDRFALRAGNEKDTENEAETVGCCSLKFEHVTLREPNTVIFDFLGKDSIRFYNE 600
Query: 179 VEVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
VD+ VF NL++F ++ K+ D+IF RL+ + LN +L M GL+AKVFRT+NAS T++
Sbjct: 601 FSVDRQVFKNLKVFKKSPKEDGDDIFDRLTTSQLNKHLSSYMTGLTAKVFRTYNASWTMS 660
Query: 356 ECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ LQ E T+ +K+ YN N+ VA LCNH RT+ +GH+ QM+KL R
Sbjct: 661 QLLQKLEVEDRTMAEKIKLYNDCNREVAILCNHKRTVGAGHEAQMEKLGDR 711
[160][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 172 bits (435), Expect = 2e-41
Identities = 89/169 (52%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 519 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEV 578
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F ++ K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++
Sbjct: 579 EVDAQVFKNLKIFKKSPKKEGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMST 638
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 639 LLKDMKATGTIAEKVKAYNDANRQVAILCNHKRTVTASHANQMEKMGER 687
[161][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 172 bits (435), Expect = 2e-41
Identities = 89/169 (52%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 519 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEV 578
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F ++ K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++
Sbjct: 579 EVDAQVFKNLKIFKKSPKKEGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMST 638
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ T+ +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 639 LLKDMKATGTIAEKVKAYNDANRQVAILCNHKRTVTASHANQMEKMGER 687
[162][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 172 bits (435), Expect = 2e-41
Identities = 95/175 (54%), Positives = 115/175 (65%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTV CCSLRVEH+ P V FDF GKDSI
Sbjct: 478 AVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSI 537
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS
Sbjct: 538 RYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNAS 597
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ P E V K+ YN+ N+ VA LCNH R P + M L+++
Sbjct: 598 ITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK 652
[163][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 171 bits (434), Expect = 2e-41
Identities = 90/172 (52%), Positives = 118/172 (68%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 420 ATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEV 479
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F ++ KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 480 EVDKQVFKNLRIFKKSPKQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQD 539
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ E TV +KVA +N N+ VA LCNH RT+ H +Q++ + E
Sbjct: 540 QIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDKLKE 591
[164][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 171 bits (434), Expect = 2e-41
Identities = 90/172 (52%), Positives = 118/172 (68%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 420 ATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEV 479
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F ++ KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 480 EVDKQVFKNLRIFKKSPKQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQD 539
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ E TV +KVA +N N+ VA LCNH RT+ H +Q++ + E
Sbjct: 540 QIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDKLKE 591
[165][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 171 bits (433), Expect = 3e-41
Identities = 95/175 (54%), Positives = 115/175 (65%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKDSI
Sbjct: 342 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHEQMDGKEYVVEFDFLGKDSI 401
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL+LF NKQP D +F RL + LN +L LMPGL+AKVFRT+NAS
Sbjct: 402 RYYNKVPVIKKVFKNLKLFLENKQPGDELFDRLYTSMLNKHLSSLMPGLTAKVFRTYNAS 461
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL E L+ + ++V +K+ YN+ N+ VA LCNH R P M L+++
Sbjct: 462 ITLQEQLKELTNKSDSVAEKLLSYNRANRAVAILCNHQRAPPKTFDQSMATLQSK 516
[166][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 171 bits (433), Expect = 3e-41
Identities = 83/168 (49%), Positives = 118/168 (70%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N V
Sbjct: 619 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTV 678
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV++ V+ ++ F K+P ++F ++ + LN +LK LMPGL+AKVFRT+NAS+TL
Sbjct: 679 EVEELVYKAIEGFRAGKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGI 738
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + + TV +K+A Y + NK VA +CN R++ H+ QM ++ +
Sbjct: 739 LHEETEDGTVLEKIAVYQRANKEVAIICNQQRSVSKSHESQMTRMNEK 786
[167][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 171 bits (433), Expect = 3e-41
Identities = 93/194 (47%), Positives = 124/194 (63%), Gaps = 28/194 (14%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENAV 181
TA YLID LALRVG EK DEADTVGCCSLRVEH+KF P T++ DFLGKDSIRY + V
Sbjct: 379 TATYLIDFLALRVGGEKDADEADTVGCCSLRVEHIKFDRKPNTITLDFLGKDSIRYFHTV 438
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
+D+ NL FC+ K+P+++IF +++ LNDYLK LM GL+AKVFRT+NAS+TL
Sbjct: 439 TLDEVACRNLSEFCK-KKPTEDIFDKINTVKLNDYLKDLMTGLTAKVFRTYNASITLCRQ 497
Query: 362 LQG-------------DPGET--------------VTDKVAFYNKQNKVVAELCNHVRTL 460
L+ PG++ V + ++FYN+ N+ VA LCNH R++
Sbjct: 498 LRRLKVRKSLDSSLMLQPGKSDDDLDKPVLVDVTDVNELISFYNEANRRVAILCNHQRSI 557
Query: 461 PSGHKGQMQKLETR 502
P H+ M K++ +
Sbjct: 558 PKQHESSMSKMQAQ 571
[168][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 171 bits (432), Expect = 4e-41
Identities = 91/172 (52%), Positives = 114/172 (66%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 429 ATACYLIDIFALRAGGEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEV 488
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EV+K VF NL++F + KQP D++F R+S LN + M GL+AKVFRT+NAS T+ +
Sbjct: 489 EVEKQVFKNLRIFKKPPKQPGDDLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQD 548
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P E TV +KV +N N+ VA LCNH RT+ H +QK+ + E
Sbjct: 549 QLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHDKLKE 600
[169][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 171 bits (432), Expect = 4e-41
Identities = 91/172 (52%), Positives = 114/172 (66%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 429 ATACYLIDIFALRAGGEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEV 488
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EV+K VF NL++F + KQP D++F R+S LN + M GL+AKVFRT+NAS T+ +
Sbjct: 489 EVEKQVFKNLRIFKKPPKQPGDDLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQD 548
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L P E TV +KV +N N+ VA LCNH RT+ H +QK+ + E
Sbjct: 549 QLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHDKLKE 600
[170][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 171 bits (432), Expect = 4e-41
Identities = 89/172 (51%), Positives = 116/172 (67%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 417 ATAMYLIDVFALRAGGEKGDDEADTVGCCSLRYEHVTLKPPNKVVFDFLGKDSIRFYQEV 476
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F + KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 477 EVDKQVFKNLRIFKKAPKQPGDDLFDRINPSLVNKQLQNYMKGLTAKVFRTYNASKTMQD 536
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ E TV +KV +N N+ VA LCNH RT+ H +QK+ + E
Sbjct: 537 QIDLIENEGTVAEKVVKFNAANRTVAILCNHQRTVSKNHSNTVQKINDKLKE 588
[171][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
Length = 904
Score = 171 bits (432), Expect = 4e-41
Identities = 91/171 (53%), Positives = 119/171 (69%), Gaps = 4/171 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLIDK ALR GNEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N
Sbjct: 538 ATAMYLIDKFALRAGNEKDTENEAETVGCCSLKFEHVTLREPNTVIFDFLGKDSIRFYNE 597
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
V++ VF NL+LF + K D+IF RL+ + LN +L MPGL+AKVFRT+NAS T++
Sbjct: 598 FTVERQVFKNLKLFKKPPKADGDDIFDRLTTSQLNKHLSNYMPGLTAKVFRTYNASHTMS 657
Query: 356 ECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
LQ E T+ +K+ YN N+ VA +CNH RT+ + H+ QM+KL R
Sbjct: 658 TLLQSLSVENRTMAEKIKLYNDCNREVAVICNHKRTVGAAHEAQMEKLADR 708
[172][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 170 bits (431), Expect = 5e-41
Identities = 91/172 (52%), Positives = 114/172 (66%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 394 ATATYLIDVFALRAGGEKGDDEADTVGCCSLRYEHITLKPPNQVIFDFLGKDSIRFYQEV 453
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F + KQP D++F R+S LN + M GL+AKVFRT+NAS T+ +
Sbjct: 454 EVDKQVFKNLRIFKKPPKQPGDDLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQD 513
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ P E TV +KV +N N+ VA LCNH RT+ H +Q++ R E
Sbjct: 514 QIDLIPNEGTVAEKVVRFNAANRTVAILCNHQRTVSKTHGHSVQRIHDRIKE 565
[173][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 170 bits (431), Expect = 5e-41
Identities = 95/182 (52%), Positives = 116/182 (63%), Gaps = 15/182 (8%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT------------TVSFD 142
+TALY IDKLALR GNEK DE ADTVGCCSLR EH+K V FD
Sbjct: 537 ATALYFIDKLALRAGNEKDVDESADTVGCCSLRYEHIKLFESAKLQETDKKEKEFVVEFD 596
Query: 143 FLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKV 322
FLGKDSIRY N V V+K VF NL+LF NK+ D++F RL +LN++L+ LM GL+ KV
Sbjct: 597 FLGKDSIRYFNRVAVEKRVFKNLKLFMENKKAGDDLFDRLDTATLNEHLRSLMDGLTVKV 656
Query: 323 FRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
FRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G M KLE
Sbjct: 657 FRTYNASITLQEQLIKLTNPDDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMAKLE 716
Query: 497 TR 502
+
Sbjct: 717 QK 718
[174][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 170 bits (431), Expect = 5e-41
Identities = 93/176 (52%), Positives = 116/176 (65%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EK+E+EADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 356 AVAVYLIDVFALRAGGEKSEEEADTVGCCSLRYEHITLKPPNTVIFDFLGKDSIRFYQEV 415
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
+VD VF NL LF + KQP +F RL + LN +L+ M GL+AKVFRT+NAS T+ E
Sbjct: 416 QVDPKVFKNLALFKKPPKQPGHQLFDRLDPSLLNKFLQNYMTGLTAKVFRTYNASKTMQE 475
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L P E +V +K+ YN N+ VA LCNH RT+ +GH + K + R E W
Sbjct: 476 QLDLIPNEGSVAEKLLKYNAANRTVAILCNHQRTVTAGHAKSVAK-SSDRIEEFKW 530
[175][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 170 bits (431), Expect = 5e-41
Identities = 91/172 (52%), Positives = 114/172 (66%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLID ALR G EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 394 ATATYLIDVFALRAGGEKGDDEADTVGCCSLRYEHITLKPPNQVIFDFLGKDSIRFYQEV 453
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F + KQP D++F R+S LN + M GL+AKVFRT+NAS T+ +
Sbjct: 454 EVDKQVFKNLRIFKKPPKQPGDDLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQD 513
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ P E TV +KV +N N+ VA LCNH RT+ H +Q++ R E
Sbjct: 514 QIDLIPNEGTVAEKVVRFNAANRTVAILCNHQRTVSKTHGHSVQRIHDRIKE 565
[176][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 170 bits (431), Expect = 5e-41
Identities = 86/173 (49%), Positives = 120/173 (69%), Gaps = 3/173 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ ALYLID LALRVGNEK ED+ADTVGCCSLRVEH+K T++ DFLGKDS+RY N V
Sbjct: 570 AVALYLIDFLALRVGNEKGEDQADTVGCCSLRVEHIKLESNNTITLDFLGKDSMRYLNTV 629
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL--- 352
++ + + L+ F + K+P+D +F L+VT LN++LK+ M GLSAKVFRT+NAS+TL
Sbjct: 630 QIREDAYKVLKTFVKGKKPTDLLFDSLTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKE 689
Query: 353 AECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ + +++ +K+ FYN+ N+ VA LCNH + P M K++ + E
Sbjct: 690 LDKMDTKEFQSIDEKILFYNRCNREVAILCNHQKAPPKNLAETMSKIDEKIQE 742
[177][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 170 bits (430), Expect = 6e-41
Identities = 93/175 (53%), Positives = 116/175 (66%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKDSI
Sbjct: 331 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDTLDASECVVEFDFLGKDSI 390
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL+LF +KQP D +F RL+ + LN +L LMPGL+AKVFRT+NAS
Sbjct: 391 RYYNKVPVIKKVFKNLKLFMEDKQPGDELFDRLNTSLLNKHLSSLMPGLTAKVFRTYNAS 450
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ + ++V +K+ YN+ N+ VA LCNH R P M L+++
Sbjct: 451 ITLQQQLKELTNESDSVAEKLLSYNRANRAVAILCNHQRAPPKTFDQSMANLQSK 505
[178][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 170 bits (430), Expect = 6e-41
Identities = 90/169 (53%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 509 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 568
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E
Sbjct: 569 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSE 628
Query: 359 CLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +KV YN N+ VA LCNH RT+ + + QM+K+ R
Sbjct: 629 LLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAVTRDQMEKMSER 677
[179][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 170 bits (430), Expect = 6e-41
Identities = 90/169 (53%), Positives = 116/169 (68%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 524 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEV 583
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A
Sbjct: 584 EVDAQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSTYMQGLTAKVFRTYNASYTMAT 643
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 644 LLKDMKATGNNAEKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSER 692
[180][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 169 bits (429), Expect = 8e-41
Identities = 89/172 (51%), Positives = 117/172 (68%), Gaps = 2/172 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 417 ATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEV 476
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F ++ KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 477 EVDKQVFKNLRIFKKSPKQPGDDLFDRINPSLVNRQLQYYMKGLTAKVFRTYNASKTMQD 536
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
+ E TV +KV +N N+ VA LCNH RT+ H +Q++ + E
Sbjct: 537 QIDLIENEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGDSIQRINDKLKE 588
[181][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 169 bits (429), Expect = 8e-41
Identities = 89/169 (52%), Positives = 121/169 (71%), Gaps = 4/169 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLIDK ALR GNEK AE+EA+TVGCCSL+ EH+ PP TV FDFLGKDSIR+ +
Sbjct: 545 ATAVYLIDKFALRAGNEKDAENEAETVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDE 604
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
V VD VF NL++F + K+ D+IF RL+ T LN +L MPGLSAKVFRT+NAS T++
Sbjct: 605 VTVDPQVFKNLKIFKKAPKKNGDDIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMS 664
Query: 356 ECLQGDPGETVT--DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+ L+ ++ +K+ YN N+ VA LCNH RT+ + H+ ++K++
Sbjct: 665 DLLKKLKNSDISMQEKIKLYNDCNRKVAILCNHKRTVGASHEAAIEKMD 713
[182][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 169 bits (429), Expect = 8e-41
Identities = 89/169 (52%), Positives = 121/169 (71%), Gaps = 4/169 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+YLIDK ALR GNEK AE+EA+TVGCCSL+ EH+ PP TV FDFLGKDSIR+ +
Sbjct: 546 ATAVYLIDKFALRAGNEKDAENEAETVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDE 605
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
V VD VF NL++F + K+ D+IF RL+ T LN +L MPGLSAKVFRT+NAS T++
Sbjct: 606 VTVDPQVFKNLKIFKKAPKKNGDDIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMS 665
Query: 356 ECLQGDPGETVT--DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+ L+ ++ +K+ YN N+ VA LCNH RT+ + H+ ++K++
Sbjct: 666 DLLKKLKNSDISMQEKIKLYNDCNRKVAILCNHKRTVGASHEAAIEKMD 714
[183][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 169 bits (428), Expect = 1e-40
Identities = 89/168 (52%), Positives = 115/168 (68%), Gaps = 1/168 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ + DFL KDSIRY+ V
Sbjct: 624 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPRNNPLLKLDFLPKDSIRYQKRV 683
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ VF +Q F K+ SDN+F +L LN +LK+LMPGLSAKVFRT+NAS+TL E
Sbjct: 684 EVEIPVFKAIQQFRSGKKGSDNLFDKLDTCKLNAHLKELMPGLSAKVFRTYNASITLDEM 743
Query: 362 LQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L + G V+ KVA Y NK VA +CNH R++ H QM +L+ +
Sbjct: 744 LNKETKGGDVSQKVAVYQHANKEVAIICNHQRSVSKSHSTQMMRLDEK 791
[184][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 169 bits (428), Expect = 1e-40
Identities = 91/176 (51%), Positives = 117/176 (66%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EK++DEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V
Sbjct: 438 AVAIYLIDVFALRAGGEKSDDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEV 497
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL +F R K+P D +F RL LN +L+ MPGL+AKVFRT+NAS T+ +
Sbjct: 498 EVDKQVFKNLAIFKRAPKKPGDQLFDRLDPPILNKHLQNYMPGLTAKVFRTYNASKTMQD 557
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L + +V +K+ YN N+ VA LCNH R++ GH ++K + E + W
Sbjct: 558 QLDLIVNKGSVAEKMLRYNAANRTVAILCNHQRSVGKGHAEAVRK-ANEKIEELEW 612
[185][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 169 bits (428), Expect = 1e-40
Identities = 88/169 (52%), Positives = 117/169 (69%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V
Sbjct: 522 ATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEV 581
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL++F + K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++
Sbjct: 582 EVDAQVFKNLKIFKKAPKKEGDEIFDRLTTSALNKHLSAYMQGLTAKVFRTYNASHTMST 641
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L+ + +KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 642 LLKDMKATGNIAEKVKAYNDANRKVAILCNHKRTVAASHANQMEKMSER 690
[186][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 169 bits (427), Expect = 1e-40
Identities = 93/175 (53%), Positives = 113/175 (64%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKD I
Sbjct: 242 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCI 301
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL+LF NKQ D++F RL+ SLN +L LMPGL+AKVFRT+NAS
Sbjct: 302 RYYNKVPVTKRVFKNLKLFMENKQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNAS 361
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ + + V +K+ YN+ N+ VA LCNH R P M L+ +
Sbjct: 362 ITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAK 416
[187][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 169 bits (427), Expect = 1e-40
Identities = 93/175 (53%), Positives = 113/175 (64%), Gaps = 8/175 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKD I
Sbjct: 320 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCI 379
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL+LF NKQ D++F RL+ SLN +L LMPGL+AKVFRT+NAS
Sbjct: 380 RYYNKVPVTKRVFKNLKLFMENKQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNAS 439
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL + L+ + + V +K+ YN+ N+ VA LCNH R P M L+ +
Sbjct: 440 ITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAK 494
[188][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 169 bits (427), Expect = 1e-40
Identities = 90/172 (52%), Positives = 114/172 (66%), Gaps = 7/172 (4%)
Frame = +2
Query: 8 ALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYE 172
A+Y IDKLALR GNEK ++ ADTVGCCSLRVEH++ V FDFLGKDSIRY
Sbjct: 314 AIYFIDKLALRAGNEKDDESADTVGCCSLRVEHIRLHKHLDGLDHVVEFDFLGKDSIRYY 373
Query: 173 NAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
N V V+K VF NL+LF ++K P D++F R+S +LN L + M GL+AKVFRTFNAS TL
Sbjct: 374 NKVPVEKQVFKNLKLFIKHKDPEDDLFDRISTVNLNKALTESMSGLTAKVFRTFNASTTL 433
Query: 353 AECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ L + TV +K+ YN+ N+ VA LCNH R P + MQ L+ +
Sbjct: 434 QDQLNKLTSDDCTVEEKILSYNRANRAVAILCNHQRAAPKTFEKSMQLLQEK 485
[189][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 169 bits (427), Expect = 1e-40
Identities = 96/214 (44%), Positives = 127/214 (59%), Gaps = 45/214 (21%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK E+EADTVGCCSLRVEH+ F + +++ DFLGKDSIRY N
Sbjct: 315 TATYLIDFLALRVGGEKDIEEEADTVGCCSLRVEHISFNEDSKSITLDFLGKDSIRYFNT 374
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL-- 352
V +D A F+NL LFC+NK+ +N+F +++++SLN YLK +MP LSAKVFRTFNAS+TL
Sbjct: 375 VCIDAAAFYNLMLFCKNKEKHENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITLER 434
Query: 353 -------------------AECLQGDPG----------------------ETVTDKVAFY 409
+ ++ + G V D + FY
Sbjct: 435 ELLKLRSLTNFSNQTTKSNLDLVKNEFGIKSDDIKQDDLLRSNLNNIVDITNVNDILRFY 494
Query: 410 NKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
N N+ VA LCNH R++P H+ M+KL ++ E
Sbjct: 495 NDANREVAILCNHQRSIPKQHESSMEKLLKQQLE 528
[190][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 168 bits (426), Expect = 2e-40
Identities = 94/204 (46%), Positives = 123/204 (60%), Gaps = 35/204 (17%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK ++EADTVGCCSLRVEH+ F +++ DFLGKDSIRY N
Sbjct: 307 TATYLIDFLALRVGGEKDTDEEADTVGCCSLRVEHITFNQQEKSITLDFLGKDSIRYYNT 366
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVT--- 349
V +D + F NL +FCRNK +N+F +++++SLN YLK +MP LSAKVFRTFNAS+T
Sbjct: 367 VVIDPSAFNNLTIFCRNKDKMENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITLER 426
Query: 350 --------------------LAECLQGDPG----------ETVTDKVAFYNKQNKVVAEL 439
L CL+ + V D + FYN N+ VA L
Sbjct: 427 ELSKISAKSAVKSEKKTKMELESCLKDELNLSNFNNEVDITNVNDILRFYNDANREVAIL 486
Query: 440 CNHVRTLPSGHKGQMQKLETRRAE 511
CNH R++P H+ M+K+ ++ E
Sbjct: 487 CNHQRSVPKQHESSMEKMIKQQQE 510
[191][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 168 bits (426), Expect = 2e-40
Identities = 88/169 (52%), Positives = 116/169 (68%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID ALR G EK EDEADTVGCCSLR EH+ PP V FD LGKDSIR+ V
Sbjct: 418 ATAMYLIDVFALRAGGEKGEDEADTVGCCSLRYEHVTLKPPNKVIFDLLGKDSIRFYQEV 477
Query: 182 EVDKAVFFNLQLFCRN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVDK VF NL++F ++ KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ +
Sbjct: 478 EVDKQVFKNLRIFKKSPKQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQD 537
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+ E TV +KVA +N N+ VA LCNH RT+ H +Q++ +
Sbjct: 538 QIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDK 586
[192][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 167 bits (424), Expect = 3e-40
Identities = 95/175 (54%), Positives = 113/175 (64%), Gaps = 10/175 (5%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDF GKDSI
Sbjct: 495 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSI 554
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 555 RYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 614
Query: 344 VTLA----ECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+TL E GD + V K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 615 ITLQQQLNELTNGD--DNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 667
[193][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 167 bits (424), Expect = 3e-40
Identities = 93/173 (53%), Positives = 113/173 (65%), Gaps = 8/173 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDF GKDSI
Sbjct: 532 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSI 591
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS
Sbjct: 592 RYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNAS 651
Query: 344 VTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+TL + L + + V K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 652 ITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 704
[194][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 167 bits (422), Expect = 5e-40
Identities = 93/204 (45%), Positives = 122/204 (59%), Gaps = 35/204 (17%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK ++EADTVGCCSLRVEH+ F +++ DFLGKDSIRY N
Sbjct: 319 TATYLIDFLALRVGGEKDTDEEADTVGCCSLRVEHITFNQQEKSITLDFLGKDSIRYYNT 378
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
V +D + F NL +FCRNK +N+F +++++SLN YLK +MP LSAKVFRTFNAS+TL
Sbjct: 379 VVIDPSAFNNLTIFCRNKDKMENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITLER 438
Query: 359 CLQGDPGET---------------------------------VTDKVAFYNKQNKVVAEL 439
L ++ V D + FYN N+ VA L
Sbjct: 439 ELSKISAKSAVKSEKRTKMELESYLKDELNLSNFNNEVDITNVNDILRFYNDANREVAIL 498
Query: 440 CNHVRTLPSGHKGQMQKLETRRAE 511
CNH R++P H+ M+K+ ++ E
Sbjct: 499 CNHQRSVPKQHESSMEKMIKQQQE 522
[195][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 167 bits (422), Expect = 5e-40
Identities = 91/172 (52%), Positives = 117/172 (68%), Gaps = 5/172 (2%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+Y IDKLALR GNEK E+EA+TVGCCSL+VE++ PP V DFLGKDSIR+E
Sbjct: 539 ATAMYFIDKLALRAGNEKDTENEAETVGCCSLKVENVSLQPPNKVFLDFLGKDSIRFEQE 598
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
VEVD VF NL++F + K D+IF RL+ + LN +L MPGL+AKVFRT+NAS T++
Sbjct: 599 VEVDAQVFKNLKMFKKAPKVEGDDIFDRLTTSQLNKHLSSYMPGLTAKVFRTYNASYTMS 658
Query: 356 ECLQ---GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
LQ + +KV YN N+ VA LCNH R++ + H QM+KL R
Sbjct: 659 TLLQKLHSKKNISDAEKVKIYNDCNRQVAILCNHKRSVGASHDAQMKKLGDR 710
[196][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 166 bits (421), Expect = 7e-40
Identities = 93/174 (53%), Positives = 115/174 (66%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+Y IDKLALR GNEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y
Sbjct: 541 ATAMYFIDKLALRAGNEKDTENEADTVGCCSLKYEHVTLEPPNKVTFDFLGKDSIPYRET 600
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
VD VF NL+LF + K D++F RL+ + LN +L M GL+AKVFRT+NAS T++
Sbjct: 601 AVVDAQVFKNLKLFKKAPKTTGDDLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMS 660
Query: 356 ECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L DP TV +KV YN N+ VA LCNH RT+ + H+ QM KL R
Sbjct: 661 TLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGASHEQQMAKLGDR 714
[197][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 166 bits (421), Expect = 7e-40
Identities = 93/174 (53%), Positives = 115/174 (66%), Gaps = 7/174 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 178
+TA+Y IDKLALR GNEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y
Sbjct: 540 ATAMYFIDKLALRAGNEKDTENEADTVGCCSLKYEHVTLEPPNKVTFDFLGKDSIPYRET 599
Query: 179 VEVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLA 355
VD VF NL+LF + K D++F RL+ + LN +L M GL+AKVFRT+NAS T++
Sbjct: 600 AVVDAQVFKNLKLFKKAPKTTGDDLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMS 659
Query: 356 ECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L DP TV +KV YN N+ VA LCNH RT+ + H+ QM KL R
Sbjct: 660 TLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGASHEQQMAKLGDR 713
[198][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 166 bits (420), Expect = 9e-40
Identities = 87/169 (51%), Positives = 112/169 (66%), Gaps = 5/169 (2%)
Frame = +2
Query: 14 YLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDK 193
YL+DKLALR G EK +D ADTVG C+LRV H+ F PP+T+ FDFLGKDSIRY EVD
Sbjct: 374 YLVDKLALRAGGEKDDDLADTVGVCTLRVGHIDFLPPSTIKFDFLGKDSIRYLQEHEVDP 433
Query: 194 AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ-- 367
VF +Q FC+ K+ +IF + T +N +L+ LMPGL+ KVFRT+NAS TL + L+
Sbjct: 434 LVFHAMQRFCKGKKKDQDIFDHIDPTKVNKHLQTLMPGLTIKVFRTYNASYTLNKLLKET 493
Query: 368 ---GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRR 505
GD TV K A Y+ NK VA LCNH + + H QM+KL+ ++
Sbjct: 494 TPAGD--STVPMKKAAYDAANKEVAVLCNHQKGVSKAHDAQMEKLQDKK 540
[199][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 166 bits (419), Expect = 1e-39
Identities = 85/171 (49%), Positives = 115/171 (67%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YLIDKLALR GNEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N V
Sbjct: 626 AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTV 685
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
EV+ V+ + F K +D++F L + LN +LK+LM GL+AKVFRT+NAS+TL
Sbjct: 686 EVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNTHLKELMAGLTAKVFRTYNASITLDLM 745
Query: 362 LQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L + + V +KV Y + NK VA +CNH RT+ H Q++KL + E
Sbjct: 746 LSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAVKIEE 796
[200][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 164 bits (416), Expect = 3e-39
Identities = 94/176 (53%), Positives = 112/176 (63%), Gaps = 9/176 (5%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPTT-----VSFDFLGKDSI 163
+ ALY IDKLALR GNEK + E ADTVGCCSLR EH+K V FDFLGKDSI
Sbjct: 192 AVALYFIDKLALRAGNEKEDGESADTVGCCSLRCEHIKLHKHLDGKDFIVEFDFLGKDSI 251
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL LF NK+ D++F RL+ ++LN YL LM GL+AKVFRT+NAS
Sbjct: 252 RYYNKVPVLKQVFKNLVLFTENKEGPDDLFDRLNTSTLNKYLNSLMDGLTAKVFRTYNAS 311
Query: 344 VTLAECL--QGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
+TL L DP E V K+ YN+ N+ VA LCNH R P QM ++ +
Sbjct: 312 ITLLNQLLELTDPDDENVASKILSYNRANRAVAVLCNHQRAAPKNFSEQMGRMNEK 367
[201][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 164 bits (414), Expect = 5e-39
Identities = 92/174 (52%), Positives = 117/174 (67%), Gaps = 8/174 (4%)
Frame = +2
Query: 29 LALRVGNEKAEDE-ADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVD 190
LALR GNEK E E ADTVGCCSLRVEHL K V FDFLGKDSIRY NAV V+
Sbjct: 2 LALRAGNEKEEGETADTVGCCSLRVEHLTLHDSKDGKEFVVEFDFLGKDSIRYVNAVPVE 61
Query: 191 KAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ- 367
K VF NL+LF NK+P+D++F RL+ + LN +L +LM GL+AKVFRT+NAS TL E L+
Sbjct: 62 KRVFRNLKLFMENKKPADDLFDRLNTSILNKHLNELMEGLTAKVFRTYNASKTLQEQLEL 121
Query: 368 -GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWV 526
+ ++ +K+ YN+ N+ VA LCNH R +P QM+ L+ + E A +
Sbjct: 122 LTEADMSLPEKMLAYNRANRAVAILCNHQRAVPKTFDKQMENLQKKMEEKEAQI 175
[202][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 164 bits (414), Expect = 5e-39
Identities = 90/176 (51%), Positives = 114/176 (64%), Gaps = 2/176 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A+YLID ALR G EKA+DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ V
Sbjct: 482 AVAIYLIDVFALRAGGEKADDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEV 541
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL +F R KQP +F RL + LN +L+ M GL+AKVFRT+NAS T+ +
Sbjct: 542 EVDPQVFKNLTIFKRPPKQPGHQLFDRLDPSVLNKHLQHYMQGLTAKVFRTYNASKTMQD 601
Query: 359 CLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW 523
L E +V +K+ YN N+ VA LCNH R++ H +QK + + E + W
Sbjct: 602 QLDLIKNEGSVAEKILKYNAANRTVAILCNHQRSVAKTHAQSVQK-ASDKIEELEW 656
[203][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment) n=1
Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 162 bits (410), Expect = 1e-38
Identities = 96/207 (46%), Positives = 121/207 (58%), Gaps = 40/207 (19%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 462 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEFVVEFDFLGKDSI 521
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSV------------------------- 268
RY N + V+K VF NLQLF NKQP D++F RL+V
Sbjct: 522 RYYNKIPVEKRVFKNLQLFLENKQPGDDLFDRLNVRISECRPVKIRCASAGAVSGCCTRP 581
Query: 269 -------TSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQN 421
+ LN +L++LM GL+AKVFRT+NAS+TL + L+ +++ K+ YN+ N
Sbjct: 582 FFSLPQTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSLPAKILSYNRAN 641
Query: 422 KVVAELCNHVRTLPSGHKGQMQKLETR 502
+ VA LCNH R P + MQ L+T+
Sbjct: 642 RAVAILCNHQRAPPKTFEKSMQNLQTK 668
[204][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 162 bits (410), Expect = 1e-38
Identities = 89/181 (49%), Positives = 110/181 (60%), Gaps = 14/181 (7%)
Frame = +2
Query: 8 ALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV 187
A+Y IDKLALR G+EK EDEADTVGCC+L+VE+++ V FDFLGKDSIRYEN VEV
Sbjct: 290 AMYFIDKLALRAGHEKDEDEADTVGCCTLKVENIEIMGDNKVKFDFLGKDSIRYENIVEV 349
Query: 188 DKAVFFNLQLFCR------NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVT 349
D V+ NL+ F R KQ D +F LN LK +M GLS KVFRT+NAS+
Sbjct: 350 DPRVYKNLEKFKRIDHTGKRKQQGDQLFETFDAQDLNKELKNIMDGLSVKVFRTYNASIV 409
Query: 350 LAECLQ--------GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRR 505
L L +TV K Y+ NK VA LCNH R++P H QM+K++ +
Sbjct: 410 LDRLLSEWEATKKGHSTAQTVDQKKVDYDIANKEVAILCNHQRSVPKTHTNQMEKIQEKL 469
Query: 506 A 508
A
Sbjct: 470 A 470
[205][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 162 bits (409), Expect = 2e-38
Identities = 93/167 (55%), Positives = 110/167 (65%), Gaps = 6/167 (3%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT---TVSFDFLGKDSIRY 169
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDF GKDSIRY
Sbjct: 476 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGHVVEFDFPGKDSIRY 535
Query: 170 ENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVT 349
N V V+K VF NLQ F NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+T
Sbjct: 536 YNKVPVEKRVFKNLQPFMENKQPEDDLFDRLNTGILNKHLQGLMEGLTAKVFRTYNASIT 595
Query: 350 LAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM 484
L + L+ P E V + YN+ N+ VA LCNH R P + M
Sbjct: 596 LQQQLKELTAPDENV-PAILSYNRANRAVAILCNHQRAPPKTFEKSM 641
[206][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 162 bits (409), Expect = 2e-38
Identities = 84/165 (50%), Positives = 112/165 (67%), Gaps = 1/165 (0%)
Frame = +2
Query: 14 YLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDK 193
YL+DKLALR G EK ED ADTVG C+LRV H++F P+T+ DFLGKDSIRY EVD
Sbjct: 427 YLVDKLALRAGGEKDEDLADTVGVCTLRVGHVEFITPSTLKLDFLGKDSIRYLQEHEVDP 486
Query: 194 AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG- 370
VF +Q FC+ K+P ++IF ++ + +N +L+ LMPGL+ KVFRT+NAS L + L+
Sbjct: 487 LVFEAMQKFCKGKKPDNDIFDQIDPSKVNKHLQTLMPGLTIKVFRTYNASFVLNKLLKDT 546
Query: 371 DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRR 505
+P +TV K A Y+ NK VA LCNH + H QM+KL ++
Sbjct: 547 NPRDTVPLKKAAYDAANKEVAVLCNHQKGESKAHGAQMEKLVDKK 591
[207][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 161 bits (407), Expect = 3e-38
Identities = 85/168 (50%), Positives = 113/168 (67%), Gaps = 3/168 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A Y IDKLALRVG+EK E+EADTVGCCSLR EH++ P V FDFLGKDSIRY N V
Sbjct: 330 AVATYFIDKLALRVGHEKGEEEADTVGCCSLRKEHIELRPDNVVRFDFLGKDSIRYVNEV 389
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ L F K+ IF +++ T+LN+YLK + LSAKVFRT+NAS+TL E
Sbjct: 390 TVLPEVYKLLGSFI--KRTDSEIFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEW 447
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+ DP +++DK+ ++NK N VA+LCNH R++P +Q ++
Sbjct: 448 FREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHVSVQSIK 495
[208][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 161 bits (407), Expect = 3e-38
Identities = 85/168 (50%), Positives = 113/168 (67%), Gaps = 3/168 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A Y IDKLALRVG+EK E+EADTVGCCSLR EH++ P V FDFLGKDSIRY N V
Sbjct: 365 AVATYFIDKLALRVGHEKGEEEADTVGCCSLRKEHIELRPDNVVRFDFLGKDSIRYVNEV 424
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
V V+ L F K+ IF +++ T+LN+YLK + LSAKVFRT+NAS+TL E
Sbjct: 425 TVLPEVYKLLGSFI--KRTDSEIFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEW 482
Query: 362 LQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 496
+ DP +++DK+ ++NK N VA+LCNH R++P +Q ++
Sbjct: 483 FREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHVSVQSIK 530
[209][TOP]
>UniRef100_Q1WWG8 IP16129p (Fragment) n=1 Tax=Drosophila melanogaster
RepID=Q1WWG8_DROME
Length = 382
Score = 158 bits (400), Expect = 2e-37
Identities = 85/149 (57%), Positives = 105/149 (70%), Gaps = 7/149 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIR 166
+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH++ V FDF GKDSIR
Sbjct: 214 AVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIR 273
Query: 167 YENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASV 346
Y N VEV+K VF NL+LF +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS
Sbjct: 274 YYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASK 333
Query: 347 TLAECLQ--GDPGETVTDKVAFYNKQNKV 427
TL L DP TV +K+ YN+ N+V
Sbjct: 334 TLQSQLDLLTDPSATVPEKLLAYNRANRV 362
[210][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 157 bits (396), Expect = 6e-37
Identities = 93/196 (47%), Positives = 115/196 (58%), Gaps = 29/196 (14%)
Frame = +2
Query: 2 STALYLIDK---------LALRVGNEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVS 136
+ ALY IDK LALR GNEK E E ADTVGCCSLRVEH+ V
Sbjct: 310 AVALYFIDKVGVTVVILKLALRAGNEKEEGETADTVGCCSLRVEHITLHDTLDASECVVE 369
Query: 137 FDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSA 316
FDFLGKDSIRY N V V K VF NL+LF +KQP D +F RL+ + LN +L LMPGL+A
Sbjct: 370 FDFLGKDSIRYYNKVPVIKKVFKNLKLFMEDKQPGDELFDRLNTSLLNKHLSSLMPGLTA 429
Query: 317 KVFRTFNASVTLAECLQG--------------DPGETVTDKVAFYNKQNKVVAELCNHVR 454
KVFRT+NAS+TL + L+ ++V +K+ YN+ N+ VA LCNH R
Sbjct: 430 KVFRTYNASITLQQQLKELTNVIILFFFPCRLPESDSVAEKLLSYNRANRAVAILCNHQR 489
Query: 455 TLPSGHKGQMQKLETR 502
P M L+++
Sbjct: 490 APPKTFDQSMANLQSK 505
[211][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 151 bits (381), Expect(2) = 7e-36
Identities = 79/128 (61%), Positives = 95/128 (74%), Gaps = 6/128 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ P V FDFLGKDSI
Sbjct: 470 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSI 529
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N + V+K VF NLQLF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 530 RYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 589
Query: 344 VTLAECLQ 367
+TL + L+
Sbjct: 590 ITLQQQLK 597
Score = 23.5 bits (49), Expect(2) = 7e-36
Identities = 11/31 (35%), Positives = 16/31 (51%)
Frame = +3
Query: 411 TSRTRWWRNCATTCGRCPVGTRARCRSWRPA 503
T T W + TT P +R CR++RP+
Sbjct: 638 TEPTALWPSSVTTREHHPRPSRNPCRTFRPS 668
[212][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 152 bits (384), Expect = 1e-35
Identities = 88/169 (52%), Positives = 105/169 (62%), Gaps = 2/169 (1%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + V
Sbjct: 545 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEV 604
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 358
EVD VF NL+ F + K D IF RL+ VFRT+NAS T+A
Sbjct: 605 EVDHQVFKNLKFFKKAPKGEGDEIFDRLT------------------VFRTYNASYTMAT 646
Query: 359 CL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 502
L Q TV +KV YN N+ VA LCNH RT+ +GH QM+KL R
Sbjct: 647 LLKQMQATGTVHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLSER 695
[213][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 151 bits (381), Expect = 3e-35
Identities = 79/123 (64%), Positives = 93/123 (75%), Gaps = 6/123 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+K P V FDFLGKDSI
Sbjct: 467 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSI 526
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V+K VF NLQLF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS
Sbjct: 527 RYYNKVPVEKRVFKNLQLFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNAS 586
Query: 344 VTL 352
+TL
Sbjct: 587 ITL 589
[214][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 150 bits (379), Expect = 5e-35
Identities = 78/171 (45%), Positives = 106/171 (61%), Gaps = 1/171 (0%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+ A YL+DKLALR G EK ED ADTVG C+LR H+KF + FDFLGKDSI+Y
Sbjct: 215 AVATYLVDKLALRAGGEKDEDLADTVGVCTLRAGHIKFMDDNVIEFDFLGKDSIQYLQQH 274
Query: 182 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 361
++D+ + LQ F + K P +IF + +N +L+ LMPGL+ KVFRT+NAS+TL
Sbjct: 275 KIDEVAYKCLQRFVQGKGPDVDIFDHVDPQKVNAHLQTLMPGLTIKVFRTYNASITLDRL 334
Query: 362 LQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
L+ +T K A Y+ NK VA LCNH + + H QM+KL ++ +
Sbjct: 335 LKDTKKNDTTLQKKATYDAANKEVAILCNHQKGVSKAHDAQMEKLAEKKKD 385
[215][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 147 bits (372), Expect = 3e-34
Identities = 78/167 (46%), Positives = 104/167 (62%), Gaps = 1/167 (0%)
Frame = +2
Query: 14 YLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDK 193
YL+DKLALR G EK ED ADTVG C+LR H+KF + FDFLGKDSI+Y ++D+
Sbjct: 499 YLVDKLALRAGGEKDEDLADTVGVCTLRAGHIKFMEDNVIEFDFLGKDSIQYLQQHKIDE 558
Query: 194 AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QG 370
+ LQ F ++K P +IF + + +N +L+ LMPGL+ KVFRT+NAS+TL L
Sbjct: 559 VAYKCLQRFVKDKGPDVDIFDLIDPSKVNAHLQTLMPGLTIKVFRTYNASITLDSLLADT 618
Query: 371 DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
D T K A Y+ NK VA LCNH + + H QM KL ++ +
Sbjct: 619 DTNLTTLQKKAKYDAANKEVAILCNHQKGVSKAHDEQMGKLNDKKKD 665
[216][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 147 bits (371), Expect = 4e-34
Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 24/188 (12%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTT------VSFDFLGKDS 160
+TA+++ID+LALRVG EK ++EADTVGCCSLRVEHLKF P + +FLGKDS
Sbjct: 213 ATAMWVIDRLALRVGGEKDTDEEADTVGCCSLRVEHLKFDPNNEGEDSKEIELEFLGKDS 272
Query: 161 IRYENAVEVDKA-----------VFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPG 307
+ ++ ++ A V+ N QLFC+ K+P+D++F L+ T LN +LK +M G
Sbjct: 273 MLFKQTIDFGSALYTENNGMGEQVYKNFQLFCKKKKPTDDVFSDLTPTILNAHLKSIMEG 332
Query: 308 LSAKVFRTFNASVTL------AECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSG 469
L+AKVFRT+NAS TL E G T +KV YN N+ VA LCNH R++
Sbjct: 333 LTAKVFRTYNASKTLQDELTKTETAAGWKRLTAAEKVVEYNNANREVAILCNHQRSVSKA 392
Query: 470 HKGQMQKL 493
+ ++ L
Sbjct: 393 QETTLENL 400
[217][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 147 bits (370), Expect = 6e-34
Identities = 72/118 (61%), Positives = 91/118 (77%), Gaps = 2/118 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPP--TTVSFDFLGKDSIRYENA 178
TA+YLID LALRVG EK DEADTVGCCSLRVEH+KF+ T++ DFLGKDSIRY N
Sbjct: 598 TAVYLIDFLALRVGGEKDADEADTVGCCSLRVEHIKFSEKKQNTITLDFLGKDSIRYFNT 657
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
V ++ + NL FC K+ S+ IF++++ LN+YL++LM GLSAKVFRT+NAS+TL
Sbjct: 658 VTLNDVAYDNLAKFCHRKKASEEIFNKINTNKLNEYLRELMDGLSAKVFRTYNASITL 715
[218][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 147 bits (370), Expect = 6e-34
Identities = 75/118 (63%), Positives = 93/118 (78%), Gaps = 2/118 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N
Sbjct: 586 TATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNT 645
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
V+V VF N+ FC+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 646 VKVHPQVFKNVVGFCKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[219][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 147 bits (370), Expect = 6e-34
Identities = 75/118 (63%), Positives = 93/118 (78%), Gaps = 2/118 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N
Sbjct: 586 TATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNT 645
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
V+V VF N+ FC+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 646 VKVHPQVFKNVVGFCKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[220][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 147 bits (370), Expect = 6e-34
Identities = 75/118 (63%), Positives = 93/118 (78%), Gaps = 2/118 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENA 178
TA YLID LALRVG EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N
Sbjct: 586 TATYLIDVLALRVGGEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNT 645
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
V+V VF N+ FC+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 646 VKVHPQVFKNVVGFCKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[221][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 146 bits (369), Expect = 8e-34
Identities = 80/128 (62%), Positives = 90/128 (70%), Gaps = 6/128 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSI 163
+ ALY IDKLALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKDSI
Sbjct: 352 AVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHEQMDGKEYVVEFDFLGKDSI 411
Query: 164 RYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
RY N V V K VF NL+LF NKQP D +F RL + LN +L LMPGL+AKVFRT+NAS
Sbjct: 412 RYYNKVPVIKKVFKNLKLFLENKQPGDELFDRLYTSMLNKHLSSLMPGLTAKVFRTYNAS 471
Query: 344 VTLAECLQ 367
+TL E L+
Sbjct: 472 ITLQEQLK 479
[222][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 146 bits (368), Expect = 1e-33
Identities = 73/152 (48%), Positives = 102/152 (67%), Gaps = 1/152 (0%)
Frame = +2
Query: 59 EDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQP 238
++EADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F K
Sbjct: 1 DNEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSK 60
Query: 239 SDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFYNK 415
+D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E L + + VT K+ Y K
Sbjct: 61 TDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQK 120
Query: 416 QNKVVAELCNHVRTLPSGHKGQMQKLETRRAE 511
NK VA +CNH RT+ H Q++KL R E
Sbjct: 121 ANKEVAIICNHQRTVSKTHGAQIEKLTARIEE 152
[223][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 142 bits (357), Expect = 2e-32
Identities = 80/191 (41%), Positives = 115/191 (60%), Gaps = 24/191 (12%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTP------PTTVSFDFLGKDS 160
+TA ++ID+LALRVG EK ++EADTVGCCSLRVEHL F P + +FLGKDS
Sbjct: 279 ATATWVIDRLALRVGGEKDTDEEADTVGCCSLRVEHLHFDPNGEGGDSKEIELEFLGKDS 338
Query: 161 IRYENAVE-----------VDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPG 307
+ ++ ++ + V+ NL+ FC+ K+ S+ +FH ++ T LN++LKQ M G
Sbjct: 339 MLFKQTIDFGATLYNDSNGLGAQVYDNLKSFCKKKKSSEEVFHVINPTMLNNHLKQFMDG 398
Query: 308 LSAKVFRTFNASVTLA------ECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSG 469
LSAKVFRT+NAS TL E T ++KV YN N+ VA LCNH R++
Sbjct: 399 LSAKVFRTYNASKTLQTELRKYEVSPAWRNLTASEKVVEYNNANREVAILCNHQRSVSKA 458
Query: 470 HKGQMQKLETR 502
+ Q++ + +
Sbjct: 459 QETQLENITAK 469
[224][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 140 bits (353), Expect = 5e-32
Identities = 71/118 (60%), Positives = 89/118 (75%), Gaps = 2/118 (1%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFT--PPTTVSFDFLGKDSIRYENA 178
TA+YLID LALRVG EK DEADTVGCCSLRVEH+KF+ T++ DFLGKDSIRY N
Sbjct: 607 TAVYLIDYLALRVGGEKDADEADTVGCCSLRVEHIKFSEKKKNTITLDFLGKDSIRYFNT 666
Query: 179 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
++ + NL FC K+ S+ IF +++ LN+YL++LM GLSAKVFRT+NAS+TL
Sbjct: 667 --LNDVAYDNLAKFCNRKKSSEGIFSKINTNKLNEYLRELMDGLSAKVFRTYNASITL 722
[225][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 139 bits (349), Expect = 2e-31
Identities = 74/145 (51%), Positives = 98/145 (67%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEERDDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL E L + ++VT+K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASHTLQEQLDKLTNAEDSVTEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P GH+ M+KL+ +
Sbjct: 121 VAILCNHQRSVPKGHQKSMEKLKEK 145
[226][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 138 bits (347), Expect = 3e-31
Identities = 74/145 (51%), Positives = 98/145 (67%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQLF NK P+D++F
Sbjct: 1 SLRVEHIELHERKDDRDHVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPADDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ + +N +L +LM GL+AKVFRT+NAS TL + L +TV +K+ YN+ N+
Sbjct: 61 DRLNTSIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTSADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P GH+ M+KL+ +
Sbjct: 121 VAILCNHQRSVPKGHQKSMEKLKEK 145
[227][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 136 bits (343), Expect = 8e-31
Identities = 74/145 (51%), Positives = 97/145 (66%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQLF NK D++F
Sbjct: 1 SLRVEHIELHEQKDDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAEGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL E L + ++VT+K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMDGLTAKVFRTYNASSTLQEQLDLLTNEDDSVTEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P GH+ M+KL+ +
Sbjct: 121 VAILCNHQRSVPKGHQKSMEKLKEK 145
[228][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 136 bits (342), Expect = 1e-30
Identities = 73/145 (50%), Positives = 98/145 (67%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQLF NK D++F
Sbjct: 1 SLRVEHIELHEQKDDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAAGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ + +N +L +LM GL+AKVFRT+NAS TL E L + +T+++K+ YN+ N+
Sbjct: 61 DRLNTSIMNKHLNELMDGLTAKVFRTYNASSTLQEQLDLLTNEDDTLSEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P GH+ M+KL+ +
Sbjct: 121 VAILCNHQRSVPKGHQKSMEKLKEK 145
[229][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 135 bits (339), Expect = 2e-30
Identities = 73/145 (50%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHISLHEQKDDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +T +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNEDDTEAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P GH M+KL+ +
Sbjct: 121 VAILCNHQRSVPKGHAKSMEKLKEK 145
[230][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 134 bits (338), Expect = 3e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[231][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 134 bits (338), Expect = 3e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[232][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 134 bits (338), Expect = 3e-30
Identities = 70/145 (48%), Positives = 97/145 (66%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLR+EH+ K V FDFLGKDSIRY N V V+K VF NLQLF K+P D++F
Sbjct: 1 SLRIEHIALHEHKDDKDYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMEKKEPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ LN +L +LM GL+AKVFRT+NAS TL + L + +++++K+ YN+ N+
Sbjct: 61 DRLNTAILNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNEDDSISEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R +P GH+ M+K++ +
Sbjct: 121 VAILCNHQRAVPKGHEKSMEKIKEK 145
[233][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[234][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[235][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[236][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[237][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[238][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[239][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 134 bits (337), Expect = 4e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[240][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 134 bits (336), Expect = 5e-30
Identities = 72/145 (49%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNAEDTVAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[241][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 134 bits (336), Expect = 5e-30
Identities = 71/145 (48%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +T+ +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLTELMDGLTAKVFRTYNASWTLQQQLDELTNADDTIAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[242][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 133 bits (334), Expect = 9e-30
Identities = 71/154 (46%), Positives = 96/154 (62%), Gaps = 33/154 (21%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTT----------------- 130
TA+YLID LALRVG EK ++EADTVGCCSLRVEH+ F+
Sbjct: 425 TAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHVSFSHNVIIKNENTNDENDNKISKI 484
Query: 131 ---------------VSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLS 265
V+ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +++
Sbjct: 485 PLPKNLEDILEDDCYVTLDFLGKDSIRYFNTVKIDKQAYINMIIFCKNKNKDEGVFDQIT 544
Query: 266 VTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 367
+ LN+YLK++MP LSAKVFRT+NAS+TL + L+
Sbjct: 545 CSKLNEYLKEIMPTLSAKVFRTYNASITLDQQLR 578
[243][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 133 bits (334), Expect = 9e-30
Identities = 72/156 (46%), Positives = 97/156 (62%), Gaps = 35/156 (22%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTP-------------------- 121
TA+YLID LALRVG EK ++EADTVGCCSLRVEH+ F
Sbjct: 428 TAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHISFAHDIPFKSVDSKEQKTNDEKVN 487
Query: 122 ----PTT----------VSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHR 259
PT ++ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +
Sbjct: 488 KIPLPTNLESISSEDCYITLDFLGKDSIRYFNTVKIDKQAYINIIIFCKNKNRDEGVFDQ 547
Query: 260 LSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 367
++ + LN+YLK++MP LSAKVFRT+NAS+TL + L+
Sbjct: 548 ITCSKLNEYLKEIMPTLSAKVFRTYNASITLDQQLK 583
[244][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 132 bits (333), Expect = 1e-29
Identities = 70/154 (45%), Positives = 96/154 (62%), Gaps = 33/154 (21%)
Frame = +2
Query: 5 TALYLIDKLALRVGNEK-AEDEADTVGCCSLRVEHLKFTPPTTV---------------- 133
TA+YLID LALRVG EK ++EADTVGCCSLRVEH+ F+ +
Sbjct: 480 TAVYLIDFLALRVGGEKDIDEEADTVGCCSLRVEHVSFSHNVIIKNENTNDENDNKISKI 539
Query: 134 ----------------SFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLS 265
+ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +++
Sbjct: 540 PLPKNLEDILEDDCYITLDFLGKDSIRYFNTVKIDKQAYINMIIFCKNKNKDEGVFDQIT 599
Query: 266 VTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 367
+ LN+YLK++MP LSAKVFRT+NAS+TL + L+
Sbjct: 600 CSKLNEYLKEIMPTLSAKVFRTYNASITLDQQLR 633
[245][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 132 bits (331), Expect = 2e-29
Identities = 69/147 (46%), Positives = 93/147 (63%)
Frame = +2
Query: 53 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 232
K +DEADTVGCC+L+VE++ PP ++ FDFLGKDSIRYE VEV+ V+ ++ F K
Sbjct: 1202 KDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRVGK 1261
Query: 233 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGETVTDKVAFYN 412
SD++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 1262 SGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDE------------------ 1303
Query: 413 KQNKVVAELCNHVRTLPSGHKGQMQKL 493
+VA +CNH RT+ H QM +L
Sbjct: 1304 ----MVAIICNHQRTISKSHTAQMTRL 1326
[246][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 131 bits (330), Expect = 3e-29
Identities = 70/145 (48%), Positives = 95/145 (65%), Gaps = 7/145 (4%)
Frame = +2
Query: 89 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 253
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 254 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKV 427
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +++ +K+ YN+ N+
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDSLAEKILSYNRANRA 120
Query: 428 VAELCNHVRTLPSGHKGQMQKLETR 502
VA LCNH R++P H M+KL+ +
Sbjct: 121 VAILCNHQRSVPKSHAKSMEKLKEK 145
[247][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 130 bits (327), Expect = 6e-29
Identities = 66/126 (52%), Positives = 90/126 (71%), Gaps = 2/126 (1%)
Frame = +2
Query: 131 VSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGL 310
V FDFLGKDSIRY N V V+K VF NLQLF NK D++F RL+ + LN +L +LM GL
Sbjct: 2 VVFDFLGKDSIRYYNEVPVEKRVFKNLQLFIENKSGEDDLFDRLNTSILNKHLNELMEGL 61
Query: 311 SAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM 484
+AKVFRT+NAS TL + L + ++V++K+ YN+ N+ VA LCNH R++P GH+ M
Sbjct: 62 TAKVFRTYNASFTLQQQLDQLTNADDSVSEKMLSYNRANRAVAVLCNHQRSVPKGHEKSM 121
Query: 485 QKLETR 502
+KL+ +
Sbjct: 122 EKLKEK 127
[248][TOP]
>UniRef100_A9A2H9 2-alkenal reductase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A2H9_NITMS
Length = 551
Score = 128 bits (321), Expect = 3e-28
Identities = 74/183 (40%), Positives = 108/183 (59%), Gaps = 9/183 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA YLI K A+RVG+EK EDEADTVG +LR EH+K T T+ FDFLGKDS+R++ +
Sbjct: 256 ATACYLIYKTAMRVGDEKDEDEADTVGATTLRKEHIKIT-SDTIEFDFLGKDSVRWQETL 314
Query: 182 EV---DKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 352
+V DK NL+ K+PS+ IFH ++ +N YL ++ G++AKVFRT+ A+ +
Sbjct: 315 KVVGDDKQFQENLKKLIEKKKPSEEIFHDITSRDVNKYLSGIVKGVTAKVFRTYQATTVV 374
Query: 353 AECL---QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE---TRRAEA 514
L G++ +K+ N A +CNH RT+P + +QK + +R
Sbjct: 375 KNYLVNHDNIKGKSDNEKLYHAKLANLEAAIMCNHKRTIPKTFEQSLQKKKDTLKKRERE 434
Query: 515 VAW 523
AW
Sbjct: 435 KAW 437
[249][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 119 bits (298), Expect = 1e-25
Identities = 64/111 (57%), Positives = 78/111 (70%), Gaps = 4/111 (3%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAV 181
+TA+YLID+ ALR GNEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + V
Sbjct: 543 ATAVYLIDQFALRAGNEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEV 602
Query: 182 EVDKAVFFNLQLFCR-NKQPSDNIFHRLSVTSLNDY---LKQLMPGLSAKV 322
EVD VF NL++F + K+ D IF RL++ L LKQ+M L K+
Sbjct: 603 EVDPQVFKNLKIFKKPPKKEGDEIFDRLTIKGLKYQQWRLKQMMLDLDPKL 653
[250][TOP]
>UniRef100_UPI000179DDCD DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2)
(TOP1mt). n=1 Tax=Bos taurus RepID=UPI000179DDCD
Length = 620
Score = 118 bits (296), Expect = 2e-25
Identities = 79/173 (45%), Positives = 100/173 (57%), Gaps = 7/173 (4%)
Frame = +2
Query: 2 STALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIR 166
+ ALY I+KLAL+ GN E+ GCCSLRVEHL+ P P V FDFLGKDSIR
Sbjct: 267 AVALYFINKLALQTGN--GEEGGGLGGCCSLRVEHLQLYPEASGSPDVVEFDFLGKDSIR 324
Query: 167 YENAVEVDK-AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNAS 343
N V V+K V+ NLQLF NK P +F RL+ SLN +L+ GL+A+VFRT+N S
Sbjct: 325 SYNRVLVEKLQVYRNLQLFMDNKGPG-TLFDRLTTASLNRHLQDPTDGLTARVFRTYNTS 383
Query: 344 VTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 499
V L LQ P G+ ++ N+ V LCNH T P + Q L++
Sbjct: 384 VMLQGQLQALPRGQRLSVWGEGTCSANRAVDFLCNHQCTTPKTFEKSAQMLQS 436