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[1][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 209 bits (531), Expect = 1e-52
Identities = 111/183 (60%), Positives = 136/183 (74%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS+ KG SD K+EKAR+LK I +IRK+YRK K EVRQR+TA+YLID ALR G
Sbjct: 358 AGSSLKGQSDLKKYEKARELKLYIDNIRKQYRKELEDKLMEVRQRATAMYLIDLFALRAG 417
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLR EH+ +PP TV FDFLGKDSIRY N V+VD VF NL++F R
Sbjct: 418 NEKGEDEADTVGCCSLRYEHISLSPPNTVVFDFLGKDSIRYYNEVQVDPQVFKNLKIFKR 477
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ K D +F RL+ + LN++L LMPGLSAKVFRT NAS T++E L+ P + +++DKV
Sbjct: 478 SPKTEGDMLFDRLNTSKLNNHLTSLMPGLSAKVFRTHNASYTMSEQLKNTPKDASISDKV 537
Query: 539 AFY 547
Y
Sbjct: 538 LAY 540
[2][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 203 bits (517), Expect = 6e-51
Identities = 113/183 (61%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS+ KG SD K+EK+R+LK I IRK YRK ++ RQR TA+YLID ALR G
Sbjct: 410 AGSSLKGQSDLKKYEKSRKLKDYIDDIRKGYRKDLKSELTVERQRGTAMYLIDVFALRAG 469
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY N VEVD VF NL++F R
Sbjct: 470 NEKGEDEADTVGCCSLRYEHVTLKPPRTVVFDFLGKDSIRYYNEVEVDPQVFKNLKIFKR 529
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RLS SLN YL LM GLSAKVFRT+NAS T+AE L+ P T+ DK+
Sbjct: 530 PPKKEGDLIFDRLSTNSLNKYLTSLMDGLSAKVFRTYNASYTMAEELKKMPKNLTLADKI 589
Query: 539 AFY 547
FY
Sbjct: 590 LFY 592
[3][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 200 bits (509), Expect = 5e-50
Identities = 105/187 (56%), Positives = 129/187 (68%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 416 SRIKGEKDWQKYETARRLKKCVERIRAQYREDWRSKEMRIRQRAVALYFIDKLALRAGNE 475
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 476 KDEGETADTVGCCSLRVEHIKLHPQLDGQDYVVEFDFLGKDSIRYYNKIPVEKRVFKNLQ 535
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQ D++F RL+ + LN YL++LM GL+AKVFRT+NAS+TL + L PGE +
Sbjct: 536 LFLENKQSEDDLFDRLNTSILNKYLQELMDGLTAKVFRTYNASITLQQQLNELTSPGENI 595
Query: 527 TDKVAFY 547
+K+ Y
Sbjct: 596 PEKILSY 602
[4][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 200 bits (509), Expect = 5e-50
Identities = 106/183 (57%), Positives = 131/183 (71%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGSA+KG SD AKFEKAR+L + IRK+Y +K RQR+TALY ID+LALR G
Sbjct: 476 AGSAWKGQSDRAKFEKARELIKHVDKIRKDYTADLKSKVMADRQRATALYFIDRLALRAG 535
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLR EH+ +PP T+ FDFLGKDS+R+ VEVD VF N++LF
Sbjct: 536 NEKGEDEADTVGCCSLRYEHVTLSPPNTIIFDFLGKDSMRFHQEVEVDPQVFKNIKLFKA 595
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP-GETVTDKV 538
+ K+ D+IF RL+ T LN +L +MPGL+AKVFRT+NAS T E L+ P TV +K+
Sbjct: 596 DPKKKGDDIFDRLTTTLLNKHLNSMMPGLTAKVFRTYNASWTFQEQLKNTPKNGTVAEKI 655
Query: 539 AFY 547
A Y
Sbjct: 656 AAY 658
[5][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 199 bits (506), Expect = 1e-49
Identities = 106/183 (57%), Positives = 131/183 (71%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGSA+KG SD AKFEKAR+L + IRK+Y +K RQR+TALY ID+LALR G
Sbjct: 439 AGSAWKGQSDRAKFEKARELIKHVDKIRKDYTADLKSKIMADRQRATALYFIDRLALRAG 498
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLR EH+ +PP T+ FDFLGKDS+R+ VEVD VF N++LF
Sbjct: 499 NEKGEDEADTVGCCSLRYEHVTLSPPNTIIFDFLGKDSMRFHQEVEVDPQVFKNIKLFKA 558
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP-GETVTDKV 538
+ K+ D+IF RL+ T LN +L +MPGL+AKVFRT+NAS T E L+ P TV +K+
Sbjct: 559 DPKKKGDDIFDRLTTTLLNKHLNGMMPGLTAKVFRTYNASWTFQEQLKNTPTNGTVAEKI 618
Query: 539 AFY 547
A Y
Sbjct: 619 AAY 621
[6][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 198 bits (503), Expect = 2e-49
Identities = 105/187 (56%), Positives = 130/187 (69%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 443 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 502
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 503 KEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 562
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS+TL + L+ +P + +
Sbjct: 563 LFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNI 622
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 623 PAKILSY 629
[7][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 198 bits (503), Expect = 2e-49
Identities = 105/187 (56%), Positives = 130/187 (69%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 434 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 493
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 494 KEEGETADTVGCCSLRVEHIKLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 553
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS+TL + L+ +P + +
Sbjct: 554 LFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTNPDDNI 613
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 614 PAKILSY 620
[8][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 196 bits (498), Expect = 9e-49
Identities = 105/187 (56%), Positives = 128/187 (68%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 584 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 643
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 644 KEEGETADTVGCCSLRVEHINLHPEMDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 703
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 704 LFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 763
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 764 PAKILSY 770
[9][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 196 bits (497), Expect = 1e-48
Identities = 101/186 (54%), Positives = 126/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR++YRK W +K +RQR ALY IDKLALR G+E
Sbjct: 171 SRLKGEKDWRKYETARKLKECVDKIREDYRKDWKSKEMRLRQRGVALYFIDKLALRAGHE 230
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K +D ADTVGCCSLRVEH+K V FDFLGKDS+RY N V ++K F N++L
Sbjct: 231 KDDDTADTVGCCSLRVEHIKLHEEWEDKECVVEFDFLGKDSVRYRNFVPIEKRAFKNMKL 290
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F KQ D++F RL+ TS+N YL +LM GLSAKVFRTFNAS+TL + LQ +P + V
Sbjct: 291 FMEGKQEGDDLFDRLTTTSVNKYLSELMEGLSAKVFRTFNASLTLQDQLQKLTNPEDNVN 350
Query: 530 DKVAFY 547
K+ Y
Sbjct: 351 AKILSY 356
[10][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 195 bits (495), Expect = 2e-48
Identities = 105/189 (55%), Positives = 129/189 (68%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A + KG D K+E AR+LK C+ +IR+ Y W +K ++RQR A+Y IDKLALR G
Sbjct: 380 AATRLKGEKDWQKYETARKLKECVETIRENYINDWKSKEMKIRQRGVAMYFIDKLALRAG 439
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRYENAVEVDKAVFFN 346
+EK E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N+V V+K VF N
Sbjct: 440 HEKEEGESADTVGCCSLRVEHITLHPEKDGQENVVEFDFLGKDSIRYTNSVPVEKRVFKN 499
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
LQLF + KQ D++F RLS TSLN +L +LMPGLSAKVFRT+NAS+TL + L + G
Sbjct: 500 LQLFMQGKQAGDDLFDRLSTTSLNKFLGELMPGLSAKVFRTYNASITLQQQLNELTEEGA 559
Query: 521 TVTDKVAFY 547
+VT K Y
Sbjct: 560 SVTAKFLQY 568
[11][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 433 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 492
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 493 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 552
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 553 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 612
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 613 PAKILSY 619
[12][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 555 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 614
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 615 PAKILSY 621
[13][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 672 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 731
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 732 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 791
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 792 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 851
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 852 PAKILSY 858
[14][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 420 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 479
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 480 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 539
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 540 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 599
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 600 PAKILSY 606
[15][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 437 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 496
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 497 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 556
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 557 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 616
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 617 PAKILSY 623
[16][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 228 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 287
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 288 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 347
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 348 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 407
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 408 PAKILSY 414
[17][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 433 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 492
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 493 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 552
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 553 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 612
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 613 PAKILSY 619
[18][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 195 bits (495), Expect = 2e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E +
Sbjct: 555 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENI 614
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 615 PAKILSY 621
[19][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 194 bits (494), Expect = 3e-48
Identities = 108/189 (57%), Positives = 130/189 (68%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LK + +IRK YR+ + +K +VRQR+ ALY IDKLALR G
Sbjct: 169 ANSKLKGEKDWEKYEVARKLKHHVVTIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAG 228
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF N
Sbjct: 229 NEKEEGETADTVGCCSLRVEHIKLYPELDGDKYVVEFDFLGKDSIRYYNKVPVEKQVFKN 288
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
LQLF NKQ D++F RLS LN +L+ LM GL+AKVFRT+NAS+TL + LQ DP E
Sbjct: 289 LQLFMENKQEGDDLFDRLSTPLLNKHLQSLMEGLTAKVFRTYNASITLQQQLQELTDPEE 348
Query: 521 TVTDKVAFY 547
++ K+ Y
Sbjct: 349 SMPSKILSY 357
[20][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 194 bits (492), Expect = 5e-48
Identities = 104/186 (55%), Positives = 129/186 (69%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR++Y+ W +K ++RQR+ ALY IDKLALR GNE
Sbjct: 637 SKLKGEKDMVKYETARKLAKKIDKIREQYQADWKSKEMKIRQRAVALYFIDKLALRAGNE 696
Query: 191 KAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ P V FDFLGKDSIRY N V V+K VF NL L
Sbjct: 697 KDEDQADTVGCCSLRVEHVELYPELNGKENVVVFDFLGKDSIRYYNEVPVEKRVFKNLLL 756
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NKQP D++F RL+ T LN +L +LM GL+AKVFRT+NAS TL E L+ +P +TV
Sbjct: 757 FKENKQPQDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASWTLQEQLKELTNPDDTVA 816
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 817 EKLLAY 822
[21][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 194 bits (492), Expect = 5e-48
Identities = 105/183 (57%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IR++YRKG + RQR+TA+YLIDK ALR G
Sbjct: 453 ANSDIKGQSDYKKFEKARELKKHIDKIREDYRKGLKSDLMADRQRATAVYLIDKFALRAG 512
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ E++ PP TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 513 NEKGEDEADTVGCCSLKYENISLRPPNTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 572
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T A L+ E TV +KV
Sbjct: 573 APKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDMKAEGTVAEKV 632
Query: 539 AFY 547
Y
Sbjct: 633 KQY 635
[22][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 193 bits (491), Expect = 6e-48
Identities = 105/187 (56%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 449 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 508
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 509 KEEGETADTVGCCSLRVEHINLHTEMDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 568
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NASVTL + L+ P E +
Sbjct: 569 LFMENKQPEDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASVTLQQQLKELTAPDENI 628
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 629 PAKILSY 635
[23][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 193 bits (491), Expect = 6e-48
Identities = 105/187 (56%), Positives = 126/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 433 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 492
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 493 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 552
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT NAS+TL + L+ P E +
Sbjct: 553 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTHNASITLQQQLKELTAPDENI 612
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 613 PAKILSY 619
[24][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 193 bits (491), Expect = 6e-48
Identities = 102/183 (55%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IR +Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 493 ANSDIKGQSDYKKFEKARELKKHIDRIRSDYKKGLKQELMAERQKATAVYLIDQFALRAG 552
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + VEVD VF NL++F +
Sbjct: 553 NEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEVEVDPQVFKNLKIFKK 612
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+G T+ +K+
Sbjct: 613 PPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKGMKSTGTIAEKI 672
Query: 539 AFY 547
Y
Sbjct: 673 KDY 675
[25][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 193 bits (491), Expect = 6e-48
Identities = 102/183 (55%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IR +Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 498 ANSDIKGQSDYKKFEKARELKKHIDRIRSDYKKGLKQELMAERQKATAVYLIDQFALRAG 557
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + VEVD VF NL++F +
Sbjct: 558 NEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEVEVDPQVFKNLKIFKK 617
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+G T+ +K+
Sbjct: 618 PPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKGMKSTGTIAEKI 677
Query: 539 AFY 547
Y
Sbjct: 678 KDY 680
[26][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 193 bits (490), Expect = 8e-48
Identities = 99/166 (59%), Positives = 120/166 (72%), Gaps = 6/166 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 419 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 478
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 479 KEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 538
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
LF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL
Sbjct: 539 LFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITL 584
[27][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 193 bits (490), Expect = 8e-48
Identities = 99/166 (59%), Positives = 120/166 (72%), Gaps = 6/166 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 419 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 478
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 479 KEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 538
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
LF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL
Sbjct: 539 LFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITL 584
[28][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 193 bits (490), Expect = 8e-48
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 241 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 300
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 301 KEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQ 360
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 361 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 411
[29][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 193 bits (490), Expect = 8e-48
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 427 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 486
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 487 KEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQ 546
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 547 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 597
[30][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 193 bits (490), Expect = 8e-48
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 473 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 532
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 533 KEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQ 592
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 593 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 643
[31][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 193 bits (490), Expect = 8e-48
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 555 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 605
[32][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 193 bits (490), Expect = 8e-48
Identities = 99/166 (59%), Positives = 120/166 (72%), Gaps = 6/166 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 423 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 482
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 483 KEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 542
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
LF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL
Sbjct: 543 LFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITL 588
[33][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 193 bits (490), Expect = 8e-48
Identities = 99/166 (59%), Positives = 120/166 (72%), Gaps = 6/166 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 421 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 480
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 481 KEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 540
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
LF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL
Sbjct: 541 LFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITL 586
[34][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 193 bits (490), Expect = 8e-48
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 555 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 605
[35][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 193 bits (490), Expect = 8e-48
Identities = 99/166 (59%), Positives = 120/166 (72%), Gaps = 6/166 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 424 SRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 483
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 484 KEEGETADTVGCCSLRVEHIKLYPEIDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 543
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
LF NK+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL
Sbjct: 544 LFMENKEPDDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITL 589
[36][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 193 bits (490), Expect = 8e-48
Identities = 104/184 (56%), Positives = 128/184 (69%), Gaps = 3/184 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FK M+D K+EKAR+LK+ I IR+ Y K + + RQ TA YLIDKLALRVG
Sbjct: 254 ATSRFKQMNDKRKYEKARRLKNQIDQIRENYTKKLQSDSIKERQLGTATYLIDKLALRVG 313
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLRVEH+K V+FDFLGKDS+RY N V++ ++ NL+LF +
Sbjct: 314 NEKDEDEADTVGCCSLRVEHIKLKEDDVVAFDFLGKDSMRYNNEVKLAHQIWKNLKLFIK 373
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD---PGETVTDK 535
KQP DN+F +SV LND+LK+ M GL+AKVFRT+NAS TL + L G +V K
Sbjct: 374 GKQPEDNLFSDISVDDLNDFLKKQMEGLTAKVFRTYNASFTLQQQLDLGGKLDGHSVQQK 433
Query: 536 VAFY 547
V FY
Sbjct: 434 VDFY 437
[37][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 192 bits (489), Expect = 1e-47
Identities = 99/171 (57%), Positives = 122/171 (71%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 438 SRIKGEKDWQKYETARRLKKCVDRIRTQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 497
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 498 KEEGETADTVGCCSLRVEHINLYPKLDDQEFVVEFDFLGKDSIRYYNKIPVEKRVFKNLQ 557
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NKQP D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L+
Sbjct: 558 LFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLK 608
[38][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 192 bits (489), Expect = 1e-47
Identities = 105/187 (56%), Positives = 126/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 426 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 485
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 486 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 545
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E V
Sbjct: 546 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENV 605
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 606 PAKILSY 612
[39][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 192 bits (489), Expect = 1e-47
Identities = 105/187 (56%), Positives = 126/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E V
Sbjct: 555 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENV 614
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 615 PAKILSY 621
[40][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 192 bits (489), Expect = 1e-47
Identities = 105/187 (56%), Positives = 126/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 495 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E V
Sbjct: 555 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENV 614
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 615 PAKILSY 621
[41][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 192 bits (488), Expect = 1e-47
Identities = 103/187 (55%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S K D+ K+E AR+LK I IR++Y+ W +K +RQRS ALY ID+LALR G+E
Sbjct: 228 SKIKAEKDYQKYETARKLKRYIDKIRQDYKADWKSKEMRIRQRSAALYFIDRLALRAGHE 287
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLR EH+K V FDFLGKDSIRY N V V+K V+ NL+
Sbjct: 288 KEEGESADTVGCCSLRYEHIKLHDQLEDKMNVVEFDFLGKDSIRYVNQVPVEKQVYKNLK 347
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG--DPGETV 526
LFC+NK+ D++F RLS TSLN YL +LM GL+AKVFRT+NAS TL E L DP ++
Sbjct: 348 LFCKNKKKGDDLFDRLSTTSLNKYLSELMEGLTAKVFRTYNASYTLQEQLHQVIDPKMSI 407
Query: 527 TDKVAFY 547
DK+ Y
Sbjct: 408 EDKILIY 414
[42][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 192 bits (487), Expect = 2e-47
Identities = 100/168 (59%), Positives = 119/168 (70%), Gaps = 6/168 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 417 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 476
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 477 KEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 536
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 496
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL +
Sbjct: 537 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQ 584
[43][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 192 bits (487), Expect = 2e-47
Identities = 104/186 (55%), Positives = 126/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR EYR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 659 SKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 718
Query: 191 KAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQL
Sbjct: 719 KDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQL 778
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK PSD++F RL+ T +N +L +LM GL+AKVFRT+NAS TL + L +P +T
Sbjct: 779 FMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEA 838
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 839 EKILSY 844
[44][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 192 bits (487), Expect = 2e-47
Identities = 104/183 (56%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+KG + RQR+TA+YLID+ ALR G
Sbjct: 489 ANSDVKGQSDYKKFEKARELKKHIDRIRKDYKKGLKDELMVNRQRATAVYLIDQFALRAG 548
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + VEVD VF NL++F +
Sbjct: 549 NEKGEDEADTVGCCSLKFEHVTLKPPNTVVFDFLGKDSIRYYDEVEVDPQVFKNLKIFKK 608
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+ T+ +KV
Sbjct: 609 APKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKKMSATGTIPEKV 668
Query: 539 AFY 547
Y
Sbjct: 669 KQY 671
[45][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 191 bits (486), Expect = 2e-47
Identities = 103/187 (55%), Positives = 130/187 (69%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK + +IR +YRK W +K + RQR+ ALY IDKLALR GNE
Sbjct: 330 SKLKGEKDWEKYEVARRLKDVVHTIRAQYRKDWKSKEIKKRQRAVALYFIDKLALRAGNE 389
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH++ P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 390 KEEGETADTVGCCSLRVEHIQLHPQLDGQEHVVEFDFLGKDSIRYYNKVSVEKPVFKNLQ 449
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG--DPGETV 526
LF +NK P++++F LS T LN +L++LM GL+AKVFRT+NAS+TL E L+ +P + +
Sbjct: 450 LFMKNKDPTEDLFDHLSTTFLNKHLQRLMDGLTAKVFRTYNASITLQEQLKALTNPEDNI 509
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 510 AGKLLSY 516
[46][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 191 bits (486), Expect = 2e-47
Identities = 103/183 (56%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD+ KFEKARQLKS I +IR++Y + +K RQ++ A+YLID ALR G
Sbjct: 339 ANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAG 398
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEVDK VF NL +F R
Sbjct: 399 GEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKR 458
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ + L P + +V +K+
Sbjct: 459 PPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKI 518
Query: 539 AFY 547
Y
Sbjct: 519 LKY 521
[47][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 191 bits (486), Expect = 2e-47
Identities = 103/183 (56%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD+ KFEKARQLKS I +IR++Y + +K RQ++ A+YLID ALR G
Sbjct: 363 ANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAG 422
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEVDK VF NL +F R
Sbjct: 423 GEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKR 482
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ + L P + +V +K+
Sbjct: 483 PPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKI 542
Query: 539 AFY 547
Y
Sbjct: 543 LKY 545
[48][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 191 bits (485), Expect = 3e-47
Identities = 104/186 (55%), Positives = 126/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR YR W +K +RQR+ ALY IDKLALR GNE
Sbjct: 640 SKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVALYFIDKLALRAGNE 699
Query: 191 KAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH+ V FDFLGKDSIRY N VEV+K VF NL+L
Sbjct: 700 KDEDQADTVGCCSLRVEHIDLHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLEL 759
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+P D++F RL+ + LN++L++LM GL+AKVFRTFNAS TL L+ DP TV
Sbjct: 760 FKENKKPGDDLFDRLNTSVLNEHLRELMEGLTAKVFRTFNASFTLQNQLRELTDPDMTVP 819
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 820 EKLLAY 825
[49][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 191 bits (485), Expect = 3e-47
Identities = 102/180 (56%), Positives = 129/180 (71%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KGMSD+ KFEKAR+LK +A+IRK+Y K ++ RQR+TA+YLID LALR G
Sbjct: 357 ANSSLKGMSDYKKFEKARELKKHVATIRKDYEKELKSEAMFERQRATAMYLIDVLALRAG 416
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ +PP V FDFLGKDSIRY VEV VF NL++F +
Sbjct: 417 GEKGDDEADTVGCCSLRYEHITLSPPNIVEFDFLGKDSIRYHQEVEVSPQVFKNLRIFKK 476
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D+IF RL + LN +L+ MPGL+AKVFRT+NAS T+ + L P E TV +K+
Sbjct: 477 APKKVGDDIFDRLDPSVLNKHLQNYMPGLTAKVFRTYNASKTMDDQLALIPNEGTVAEKL 536
[50][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 191 bits (485), Expect = 3e-47
Identities = 104/183 (56%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IR++YR G ++ RQR+TA+YLIDK ALR G
Sbjct: 457 ANSDIKGQSDYKKFEKARELKKHIDRIREDYRVGLKSELMADRQRATAVYLIDKFALRAG 516
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ E++ PP TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 517 NEKGEDEADTVGCCSLKYENVSLRPPNTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 576
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T A L+ E TV +KV
Sbjct: 577 APKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDMKAEGTVAEKV 636
Query: 539 AFY 547
Y
Sbjct: 637 KQY 639
[51][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 191 bits (485), Expect = 3e-47
Identities = 103/183 (56%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD+ KFEKARQLKS I +IR++Y + +K RQ++ A+YLID ALR G
Sbjct: 363 ANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKLMLERQKAVAIYLIDVFALRAG 422
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEVDK VF NL +F R
Sbjct: 423 GEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKR 482
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP +F RL + LN YL+ MPGL+AKVFRT+NAS T+ + L P + +V +K+
Sbjct: 483 PPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKI 542
Query: 539 AFY 547
Y
Sbjct: 543 LKY 545
[52][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 191 bits (484), Expect = 4e-47
Identities = 102/186 (54%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L + IR YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 689 SKLKGEKDWQKYETARKLAKSVDKIRATYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 748
Query: 191 KAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH+ K V FDFLGKDSIRY N V V+K VF +LQL
Sbjct: 749 KDEDQADTVGCCSLRVEHIALHEKKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKSLQL 808
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK P D +F RL+ T +N +L +LM GL+AKVFRT+NAS TL + L+ DP TV
Sbjct: 809 FMENKSPGDELFDRLNTTVMNKHLNELMDGLTAKVFRTYNASWTLQQQLEELTDPNSTVA 868
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 869 EKILSY 874
[53][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 191 bits (484), Expect = 4e-47
Identities = 106/187 (56%), Positives = 128/187 (68%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D AK+E AR+LK + IR EYR+ W +K VRQR+ ALY IDKLALR GNE
Sbjct: 108 SRIKGEKDWAKYETARKLKESVDRIRNEYREDWKSKEMRVRQRAVALYFIDKLALRAGNE 167
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH++ V FDFLGKDSIRYEN+V V+K VF NL+
Sbjct: 168 KEEGETADTVGCCSLRVEHIQLYEEQDGMEFVVKFDFLGKDSIRYENSVPVEKRVFKNLK 227
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--QGDPGETV 526
LF NK+ DN+F RL+ + LN YL++LM GL+AKVFRT+NAS TL L D ++V
Sbjct: 228 LFTENKKGEDNLFDRLNTSILNKYLQELMEGLTAKVFRTYNASSTLQNQLVELTDADDSV 287
Query: 527 TDKVAFY 547
T K+ Y
Sbjct: 288 TAKMLSY 294
[54][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 191 bits (484), Expect = 4e-47
Identities = 106/187 (56%), Positives = 128/187 (68%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D AK+E AR+LK + IR EYR+ W +K VRQR+ ALY IDKLALR GNE
Sbjct: 547 SRIKGEKDWAKYETARKLKESVDRIRNEYREDWKSKEMRVRQRAVALYFIDKLALRAGNE 606
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH++ V FDFLGKDSIRYEN+V V+K VF NL+
Sbjct: 607 KEEGETADTVGCCSLRVEHIQLYEEQDGMEFVVKFDFLGKDSIRYENSVPVEKRVFKNLK 666
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--QGDPGETV 526
LF NK+ DN+F RL+ + LN YL++LM GL+AKVFRT+NAS TL L D ++V
Sbjct: 667 LFTENKKGEDNLFDRLNTSILNKYLQELMEGLTAKVFRTYNASSTLQNQLVELTDADDSV 726
Query: 527 TDKVAFY 547
T K+ Y
Sbjct: 727 TAKMLSY 733
[55][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 191 bits (484), Expect = 4e-47
Identities = 98/181 (54%), Positives = 126/181 (69%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I +IR+ Y K +++ +Q + A YLID+LALR G
Sbjct: 173 ASSSLKGQSDMLKYEKARTLKDYIDNIRRTYTKDFSSSDPTKQQIAVATYLIDRLALRAG 232
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+VEH+ P ++ FDFLGKDSIRY N VEVD+ V+ + F +
Sbjct: 233 NEKDEDEADTVGCCSLKVEHVSLIAPKSLQFDFLGKDSIRYFNTVEVDERVYKAIGQFKK 292
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGETVTDKVAF 544
K+ D++F RL T LN +LK +MPGL+AKVFRT+NAS+TL LQ GET + +A
Sbjct: 293 GKKGGDDLFERLDTTKLNLHLKGIMPGLTAKVFRTYNASITLDTLLQDTRGETTIEIIAD 352
Query: 545 Y 547
Y
Sbjct: 353 Y 353
[56][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 191 bits (484), Expect = 4e-47
Identities = 104/186 (55%), Positives = 125/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR YR W +K +RQR+ ALY IDKLALR GNE
Sbjct: 635 SKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVALYFIDKLALRAGNE 694
Query: 191 KAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDFLGKDSIRY N VEV+K VF NL+L
Sbjct: 695 KDEDQADTVGCCSLRVEHIELHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLEL 754
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+P D++F RL+ + LN++L+ LM GL+AKVFRTFNAS TL L DP TV
Sbjct: 755 FKENKKPGDDLFDRLNTSVLNEHLRDLMDGLTAKVFRTFNASFTLQNQLAELTDPNMTVP 814
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 815 EKMLAY 820
[57][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 191 bits (484), Expect = 4e-47
Identities = 104/183 (56%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+YRK +K RQR+TA+YLID+ ALR G
Sbjct: 498 ANSDIKGQSDFKKFEKARELKKHIDRIRKDYRKDLNSKMMADRQRATAIYLIDQFALRAG 557
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ +H+ PP TV FDFLGKDSIR+ + V+VD VF NL+LF +
Sbjct: 558 NEKGEDEADTVGCCSLKFQHITLRPPETVIFDFLGKDSIRFYDEVKVDPQVFKNLKLFKK 617
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K D+IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+ TV +KV
Sbjct: 618 EPKTTGDDIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMARLLKEMKATGTVQEKV 677
Query: 539 AFY 547
Y
Sbjct: 678 KAY 680
[58][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 190 bits (483), Expect = 5e-47
Identities = 98/164 (59%), Positives = 124/164 (75%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKGMSD+ K+EKAR+LK+ I +IR +Y K + RQ TA YLID LALRVG
Sbjct: 269 ASSGFKGMSDYNKYEKARKLKNFIHAIRDDYNKKMKSNDIIHRQLGTATYLIDFLALRVG 328
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK E+EADTVGCCSLRVEH+ F + +++ DFLGKDSIRY N V +D A F+NL LF
Sbjct: 329 GEKDIEEEADTVGCCSLRVEHISFNEDSKSITLDFLGKDSIRYFNTVCIDAAAFYNLMLF 388
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
C+NK+ +N+F +++++SLN YLK +MP LSAKVFRTFNAS+TL
Sbjct: 389 CKNKEKHENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITL 432
[59][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 190 bits (483), Expect = 5e-47
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 713 SKLKGEKDHIKYETARRLDKFIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 772
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 773 KDEDQADTVGCCSLRVEHVQLHKELNNKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 832
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP +V
Sbjct: 833 FMENKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQNQLDLLTDPNASVA 892
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 893 EKLLTY 898
[60][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 190 bits (483), Expect = 5e-47
Identities = 104/187 (55%), Positives = 125/187 (66%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 435 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 494
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTV CCSLRVEH+ P V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 495 KEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 554
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETV 526
LF NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+ P E V
Sbjct: 555 LFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENV 614
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 615 PAKILSY 621
[61][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 190 bits (482), Expect = 7e-47
Identities = 99/170 (58%), Positives = 121/170 (71%), Gaps = 6/170 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR W +K ++RQR+ ALY IDKLALR GNE
Sbjct: 426 SRIKGEKDWQKYETARRLKKCVDRIRSQYRDDWKSKEMKIRQRAVALYFIDKLALRAGNE 485
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEHL P V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 486 KEEGETADTVGCCSLRVEHLTLHPEMDGQEFVVEFDFLGKDSIRYYNKVPVEKRVFKNLQ 545
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
LF +K+P D++F RL+ + LN +L++LM GL+AKVFRT+NAS+TL + L
Sbjct: 546 LFMEDKEPEDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQL 595
[62][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 190 bits (482), Expect = 7e-47
Identities = 100/182 (54%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFEKAR+LK + IR Y + + + V QR+ A+Y ID+LALRVGNE
Sbjct: 259 SSVKGQSDMVKFEKARKLKDKVDDIRASYMEDFKSNDLHVAQRAVAMYFIDRLALRVGNE 318
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V V V+ LQ F R K
Sbjct: 319 KGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTRRK 378
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL + DP + DK+A
Sbjct: 379 SPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLA 438
Query: 542 FY 547
++
Sbjct: 439 YF 440
[63][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 190 bits (482), Expect = 7e-47
Identities = 100/182 (54%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFEKAR+LK + IR Y + + + V QR+ A+Y ID+LALRVGNE
Sbjct: 259 SSVKGQSDMVKFEKARKLKDKVDDIRASYMEDFKSNDLHVAQRAVAMYFIDRLALRVGNE 318
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V V V+ LQ F R K
Sbjct: 319 KGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTRRK 378
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL + DP + DK+A
Sbjct: 379 SPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLA 438
Query: 542 FY 547
++
Sbjct: 439 YF 440
[64][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 190 bits (482), Expect = 7e-47
Identities = 104/183 (56%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+LK I IRK+Y+K +++K RQ + A YLID ALR G
Sbjct: 357 ADSSLKGRSDFKKFEKARELKKYIHRIRKDYKKNFSSKVMLERQMAVATYLIDVFALRAG 416
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EKAEDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY V V + VF NL+LF +
Sbjct: 417 GEKAEDEADTVGCCSLRYEHVTLKPPNTVVFDFLGKDSIRYYQEVNVHEKVFKNLRLFKK 476
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ KQP D++F RL+ LN +L+ +PGLSAKVFRT+NAS T+ + L P E +V +KV
Sbjct: 477 SPKQPGDDLFDRLTPNILNKHLQNYLPGLSAKVFRTYNASKTMQDQLDLIPNEGSVGEKV 536
Query: 539 AFY 547
Y
Sbjct: 537 VKY 539
[65][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 189 bits (481), Expect = 9e-47
Identities = 106/189 (56%), Positives = 128/189 (67%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LK IRK YR+ + +K +VRQR+ ALY IDKLALR G
Sbjct: 169 ANSKLKGEKDWEKYEIARKLKHHAEKIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAG 228
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N V V+K VF N
Sbjct: 229 NEKEEGESADTVGCCSLRVEHIKLYPELDGEKHVVEFDFLGKDSIRYYNKVPVEKQVFKN 288
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
LQLF NK+ D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + LQ DP E
Sbjct: 289 LQLFMENKEEGDDLFDRLNTPLLNKHLQSLMEGLTAKVFRTYNASITLQQQLQELTDPEE 348
Query: 521 TVTDKVAFY 547
++ K+ Y
Sbjct: 349 SIPAKILSY 357
[66][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 189 bits (481), Expect = 9e-47
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 724 SKLKGEKDHIKYETARRLDKSIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 783
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 784 KDEDQADTVGCCSLRVEHVQLHKELNDKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 843
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 844 FMEHKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDPSATVP 903
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 904 EKLLTY 909
[67][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 189 bits (481), Expect = 9e-47
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 712 SKLKGEKDHIKYETARRLDKSIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 771
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 772 KDEDQADTVGCCSLRVEHVQLHKELNDKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 831
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 832 FMEHKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDPSATVP 891
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 892 EKLLTY 897
[68][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 189 bits (480), Expect = 1e-46
Identities = 104/187 (55%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D KFE AR+LK + IR +Y+ W +K + RQR+ ALY IDKLALR GNE
Sbjct: 261 SKLKGEKDWQKFEVARKLKDVVHKIRAQYQADWKSKEMKKRQRAVALYFIDKLALRAGNE 320
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 321 KEEGETADTVGCCSLRVEHIKLHSKLDGQEHVVEFDFLGKDSIRYYNKVSVEKPVFKNLQ 380
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG--DPGETV 526
LF +NK P D++F RLS LN +L++LM GL+AKVFRT+NAS+TL E L+ +P ++V
Sbjct: 381 LFMKNKDPGDDLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNASITLQEQLKALTNPEDSV 440
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 441 AGKLLSY 447
[69][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 189 bits (480), Expect = 1e-46
Identities = 104/187 (55%), Positives = 127/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D KFE AR+LK + IR +Y+ W +K + RQR+ ALY IDKLALR GNE
Sbjct: 261 SKLKGEKDWQKFEVARKLKDVVHKIRAQYQADWKSKEMKKRQRAVALYFIDKLALRAGNE 320
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+K V FDFLGKDSIRY N V V+K VF NLQ
Sbjct: 321 KEEGETADTVGCCSLRVEHIKLHSKLDGQEHVVEFDFLGKDSIRYYNKVSVEKPVFKNLQ 380
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG--DPGETV 526
LF +NK P D++F RLS LN +L++LM GL+AKVFRT+NAS+TL E L+ +P ++V
Sbjct: 381 LFMKNKDPGDDLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNASITLQEQLKALTNPEDSV 440
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 441 AGKLLSY 447
[70][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 265 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 324
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 325 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 384
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 385 FMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 444
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 445 EKLLAY 450
[71][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 658 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 717
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 718 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 777
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 778 FMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 837
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 838 EKLLAY 843
[72][TOP]
>UniRef100_Q1WWG8 IP16129p (Fragment) n=1 Tax=Drosophila melanogaster
RepID=Q1WWG8_DROME
Length = 382
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 171 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 230
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 231 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 290
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 291 FMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 350
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 351 EKLLAY 356
[73][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 264 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 323
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 324 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 383
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 384 FMEHKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 443
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 444 EKLLAY 449
[74][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 654 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 713
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 714 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 773
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 774 FMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 833
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 834 EKLLAY 839
[75][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 653 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 712
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 713 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 772
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 773 FMEHKKDGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 832
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 833 EKLLAY 838
[76][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 674 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 733
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 734 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 793
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 794 FMEHKKDGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 853
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 854 EKLLAY 859
[77][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 189 bits (480), Expect = 1e-46
Identities = 104/183 (56%), Positives = 126/183 (68%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KGMSD KFEK+R+LK+ I IR +YRK +K RQ + A YLID ALR G
Sbjct: 326 ANSSLKGMSDFKKFEKSRELKNYIDIIRADYRKNLKSKVMLDRQIAVATYLIDVFALRAG 385
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY VEVDK VF NL +F R
Sbjct: 386 GEKSEDEADTVGCCSLRYEHISLKPPNTVVFDFLGKDSIRYYQEVEVDKQVFKNLSIFKR 445
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ + L P E +VT+K+
Sbjct: 446 PPKEPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGSVTEKM 505
Query: 539 AFY 547
Y
Sbjct: 506 VRY 508
[78][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 189 bits (480), Expect = 1e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 656 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 715
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 716 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 775
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 776 FMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 835
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 836 EKLLAY 841
[79][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 189 bits (479), Expect = 1e-46
Identities = 99/182 (54%), Positives = 127/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD K+EKAR LK I IR Y K +A+K +Q + A YLIDKLALR G
Sbjct: 578 ASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAG 637
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N VEV+ AVF +Q F
Sbjct: 638 NEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRS 697
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD-PGETVTDKVA 541
K+ S ++F L + LN +LK+LMPGL+AKVFRT+NAS+TL + L + G V +KV
Sbjct: 698 GKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVV 757
Query: 542 FY 547
Y
Sbjct: 758 VY 759
[80][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 189 bits (479), Expect = 1e-46
Identities = 103/186 (55%), Positives = 123/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 265 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 324
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 325 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 384
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K+ D++F RL LN++LK+LM GL+AKVFRT+NAS TL L DP TV
Sbjct: 385 FMEHKKEGDDLFDRLKTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVP 444
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 445 EKLLAY 450
[81][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 189 bits (479), Expect = 1e-46
Identities = 102/183 (55%), Positives = 126/183 (68%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ G SD KFEKAR+LK I IRK+YR+ + +K RQ++ A Y ID ALR G
Sbjct: 338 ANSSLNGQSDLKKFEKARELKKYIGDIRKDYRESFKSKIMLERQKAVATYFIDVFALRAG 397
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+EDEADTVGCCSLR EH+ PP TV FDFLGKDSIRY VEV+K VF NL++F R
Sbjct: 398 GEKSEDEADTVGCCSLRFEHVTLKPPNTVIFDFLGKDSIRYHQEVEVEKQVFKNLKIFKR 457
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D++F RL + LN YL+ MPGL+AKVFRT+NAS T+ + L P E TV +K+
Sbjct: 458 PPKKDGDDLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKL 517
Query: 539 AFY 547
Y
Sbjct: 518 LKY 520
[82][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 188 bits (478), Expect = 2e-46
Identities = 100/182 (54%), Positives = 128/182 (70%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+LK I IR Y K + +K RQ + A YLIDKLALR G
Sbjct: 547 ASSSLKGQSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAG 606
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N V V K VF +QLF
Sbjct: 607 NEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYKPVFKAIQLFRS 666
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QGDPGETVTDKVA 541
K+ D++F +L + LN +LK+LMPGL+AKVFRT+NASVTL + L + G + +KVA
Sbjct: 667 GKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVA 726
Query: 542 FY 547
Y
Sbjct: 727 VY 728
[83][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 188 bits (478), Expect = 2e-46
Identities = 103/186 (55%), Positives = 124/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 667 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 726
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 727 KDEDQADTVGCCSLRVEHVQLHRELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 786
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL + L D TV
Sbjct: 787 FMENKKEGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQDQLDKLTDGDATVA 846
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 847 EKLLAY 852
[84][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 188 bits (478), Expect = 2e-46
Identities = 103/186 (55%), Positives = 123/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 733 SKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 792
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 793 KDEDQADTVGCCSLRVEHVQLHKELNCKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 852
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L D TV
Sbjct: 853 FMENKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDGSATVA 912
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 913 EKLLAY 918
[85][TOP]
>UniRef100_A4HB62 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania braziliensis
RepID=A4HB62_LEIBR
Length = 637
Score = 188 bits (478), Expect = 2e-46
Identities = 99/184 (53%), Positives = 125/184 (67%), Gaps = 3/184 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+LK + IR Y + + + V QR+ A+Y ID+LALRVG
Sbjct: 257 ASSSVKGQSDMMKFEKARKLKDKVDDIRASYMEDFKSNDVHVAQRAVAMYFIDRLALRVG 316
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLRVEH++ V FDFLGKDSIRY+N V V V+ LQ F R
Sbjct: 317 NEKGEDEADTVGCCSLRVEHIQLMSDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTR 376
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE---TVTDK 535
K P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL + P + ++ DK
Sbjct: 377 RKSPGTDIFDQLNPTQLNDHLKSFMNGLSAKVFRTYNASITLDRWFKEKPVDSKWSIADK 436
Query: 536 VAFY 547
+A++
Sbjct: 437 LAYF 440
[86][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 188 bits (478), Expect = 2e-46
Identities = 100/183 (54%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD+ KFEKAR+LK I IRK+Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 502 ANSDIKGLSDYKKFEKARELKKHIDRIRKDYKKGLKHELMSERQKATAVYLIDQFALRAG 561
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 562 NEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 621
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKV 538
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A L+ T+ +K+
Sbjct: 622 PPKREGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMATLLKDLKSTGTIAEKI 681
Query: 539 AFY 547
Y
Sbjct: 682 KDY 684
[87][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 188 bits (478), Expect = 2e-46
Identities = 100/183 (54%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD+ KFEKAR+LK I IRK+Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 502 ANSDIKGLSDYKKFEKARELKKHIDRIRKDYKKGLKHELMSERQKATAVYLIDQFALRAG 561
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 562 NEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 621
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKV 538
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A L+ T+ +K+
Sbjct: 622 PPKREGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASYTMATLLKDLKSTGTIAEKI 681
Query: 539 AFY 547
Y
Sbjct: 682 KDY 684
[88][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 188 bits (477), Expect = 3e-46
Identities = 97/168 (57%), Positives = 123/168 (73%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 504 ANSDIKGQSDYKKFEKARELKKHIDRIRKDYKKSLKHELMSERQKATAVYLIDQFALRAG 563
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP+TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 564 NEKGEDEADTVGCCSLKYEHVTLKPPSTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 623
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+
Sbjct: 624 APKREGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLK 671
[89][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 187 bits (476), Expect = 3e-46
Identities = 100/186 (53%), Positives = 125/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L CI IR+EY+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 606 SKLKGEKDWQKYETARRLHKCIDKIREEYKDDWKSKEMRIRQRAVALYFIDKLALRAGNE 665
Query: 191 KAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQL
Sbjct: 666 KDEDQADTVGCCSLRVEHISLHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQL 725
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F +K P D++F RL+ +N +L +LM GL+AKVFRT+NAS TL + L + ++V
Sbjct: 726 FMEHKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNADDSVA 785
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 786 EKILAY 791
[90][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 187 bits (476), Expect = 3e-46
Identities = 97/164 (59%), Positives = 121/164 (73%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKGMSD+ K+EKAR+LK I +IR +YRK + RQ TA YLID LALRVG
Sbjct: 261 ASSGFKGMSDYNKYEKARKLKDHIDAIRSDYRKKMTSGDITQRQLGTATYLIDFLALRVG 320
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK ++EADTVGCCSLRVEH+ F +++ DFLGKDSIRY N V +D + F NL +F
Sbjct: 321 GEKDTDEEADTVGCCSLRVEHITFNQQEKSITLDFLGKDSIRYYNTVVIDPSAFNNLTIF 380
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
CRNK +N+F +++++SLN YLK +MP LSAKVFRTFNAS+TL
Sbjct: 381 CRNKDKMENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITL 424
[91][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 187 bits (475), Expect = 4e-46
Identities = 103/187 (55%), Positives = 126/187 (67%), Gaps = 8/187 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK + IR +YR W +K + RQR+ ALY IDKLALR GNE
Sbjct: 357 SKLKGEKDWQKYELARRLKGVVDKIRAQYRADWKSKEMKKRQRAVALYFIDKLALRAGNE 416
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH++ V FDFLGKDSIRY N V V+K V+ NL+
Sbjct: 417 KEEGETADTVGCCSLRVEHIQLHREMDGQEHVVEFDFLGKDSIRYYNKVPVEKQVYKNLR 476
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG--DPGETV 526
LF +NK P D++F RLS TSLN +L+ LM GL+AKVFRT+NAS+TL E L+ D + V
Sbjct: 477 LFMQNKDPGDDLFDRLSTTSLNKHLQDLMDGLTAKVFRTYNASITLQEQLKALTDAEDNV 536
Query: 527 TDKVAFY 547
K+ Y
Sbjct: 537 AAKILSY 543
[92][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 187 bits (475), Expect = 4e-46
Identities = 99/169 (58%), Positives = 119/169 (70%), Gaps = 4/169 (2%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 433 SRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNE 492
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT---TVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
K E E ADTVGCCSLRVEH+ P V FDF GKDSIRY N V V+K VF NLQ F
Sbjct: 493 KEEGETADTVGCCSLRVEHINLHPELDGHVVEFDFPGKDSIRYYNKVPVEKRVFKNLQPF 552
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
NKQP D++F RL+ LN +L+ LM GL+AKVFRT+NAS+TL + L+
Sbjct: 553 MENKQPEDDLFDRLNTGILNKHLQGLMEGLTAKVFRTYNASITLQQQLK 601
[93][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 187 bits (475), Expect = 4e-46
Identities = 96/181 (53%), Positives = 123/181 (67%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I IR+ Y +++ +Q + A YLID+LALR G
Sbjct: 303 ASSSLKGQSDMQKYEKARMLKDYIDDIRRTYTHDFSSSDPTKQQIAVATYLIDRLALRAG 362
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+VEH+ P ++ FDFLGKDSIRY N VEVD+ V+ + F +
Sbjct: 363 NEKDEDEADTVGCCSLKVEHVTLVAPKSLQFDFLGKDSIRYFNTVEVDERVYKAIGQFKK 422
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGETVTDKVAF 544
K+ D++F RL T LN +LK +MP L+AKVFRT+NAS+TL LQ GET + +A
Sbjct: 423 GKKEGDDLFERLDTTKLNLHLKGIMPSLTAKVFRTYNASITLDNLLQDTTGETTIEIIAD 482
Query: 545 Y 547
Y
Sbjct: 483 Y 483
[94][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 187 bits (475), Expect = 4e-46
Identities = 101/186 (54%), Positives = 125/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR YR W +K +RQR+ A+Y IDKLALR GNE
Sbjct: 658 SKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNE 717
Query: 191 KAEDEADTVGCCSLRVEHLKFTPP-----TTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K +D+ADTVGCCSLR EH+ V FDFLGKDSIRY N VEV+K VF NL+L
Sbjct: 718 KDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLEL 777
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+P D++F RL+ + +N+YLK LM GL+AKVFRTFNAS TL + L+ DP +V
Sbjct: 778 FKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVP 837
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 838 EKLLAY 843
[95][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 187 bits (475), Expect = 4e-46
Identities = 97/164 (59%), Positives = 121/164 (73%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKGMSD+ K+EKAR+LK I +IR +YRK + RQ TA YLID LALRVG
Sbjct: 273 ASSGFKGMSDYNKYEKARKLKDHIDAIRDDYRKKMTSGDITQRQLGTATYLIDFLALRVG 332
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK ++EADTVGCCSLRVEH+ F +++ DFLGKDSIRY N V +D + F NL +F
Sbjct: 333 GEKDTDEEADTVGCCSLRVEHITFNQQEKSITLDFLGKDSIRYYNTVVIDPSAFNNLTIF 392
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
CRNK +N+F +++++SLN YLK +MP LSAKVFRTFNAS+TL
Sbjct: 393 CRNKDKMENVFDQINMSSLNQYLKSIMPELSAKVFRTFNASITL 436
[96][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 187 bits (475), Expect = 4e-46
Identities = 99/182 (54%), Positives = 123/182 (67%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFEKAR+LK + IR Y + + + V QR+ A+Y ID+LALRVGNE
Sbjct: 259 SSVKGQSDMVKFEKARKLKDKVDDIRASYMEAFKSNDLHVAQRAVAMYFIDRLALRVGNE 318
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V V V+ LQ F K
Sbjct: 319 KGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTCRK 378
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL + DP + DK+A
Sbjct: 379 SPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLA 438
Query: 542 FY 547
++
Sbjct: 439 YF 440
[97][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 187 bits (474), Expect = 6e-46
Identities = 98/182 (53%), Positives = 127/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I IR Y K +A+K RQ + A YLIDKLALR G
Sbjct: 564 ASSSLKGQSDKEKYEKARLLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAG 623
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE+++ PP+ + FDFLGKDSIRY+N VEV+ V+ +Q F
Sbjct: 624 NEKDDDEADTVGCCTLKVENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRT 683
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD-PGETVTDKVA 541
K+ D++F +L + LN +LK LMPGL+AKVFRT+NAS+TL E L + G V +K+
Sbjct: 684 GKRGGDDLFDKLDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIV 743
Query: 542 FY 547
Y
Sbjct: 744 VY 745
[98][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 187 bits (474), Expect = 6e-46
Identities = 98/186 (52%), Positives = 129/186 (69%), Gaps = 5/186 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S K +D K+EKAR+LK+ I IR+ Y + + RQ TA YLIDKLALRVG
Sbjct: 366 AESKLKAENDKKKYEKARRLKNLIGQIRENYERKLRSSDPVDRQLGTATYLIDKLALRVG 425
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK+E+EADTVGCCSLRVEH++ T + FDFLGKDS+RY+N V+V + V+ N+Q F +
Sbjct: 426 NEKSEEEADTVGCCSLRVEHIQVIEDTQIGFDFLGKDSMRYQNTVKVTEIVWKNMQSFIK 485
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-----QGDPGETVT 529
NK+P D++F R+ +SLN+YLK M GL+AKVFRT+NAS TL + L +G +
Sbjct: 486 NKKPGDDLFDRIDASSLNEYLKSQMEGLTAKVFRTYNASHTLQKELDKADEEGLDKMDLK 545
Query: 530 DKVAFY 547
DK+ FY
Sbjct: 546 DKLNFY 551
[99][TOP]
>UniRef100_C4Q6C8 DNA topoisomerase type I, putative n=2 Tax=Schistosoma mansoni
RepID=C4Q6C8_SCHMA
Length = 587
Score = 187 bits (474), Expect = 6e-46
Identities = 99/170 (58%), Positives = 119/170 (70%), Gaps = 5/170 (2%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR L I IR +YR + K +RQR+ ALY IDKLALR GNE
Sbjct: 354 SRLKGEKDWKKYETARCLHKVIDKIRADYRADFKHKEMRIRQRAVALYFIDKLALRAGNE 413
Query: 191 KAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K EDEADTVGCCSLR EH+K P V FDFLGKDSIRY+NAV V K VF N++L
Sbjct: 414 KDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIRYQNAVSVPKRVFKNVKL 473
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
F +NK+ +D++F RL+ T LN YL++LM GL+AKVFRT+NAS TL E L+
Sbjct: 474 FLKNKKENDDLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASRTLEEQLE 523
[100][TOP]
>UniRef100_C4Q6C7 DNA topoisomerase type I, putative n=1 Tax=Schistosoma mansoni
RepID=C4Q6C7_SCHMA
Length = 652
Score = 187 bits (474), Expect = 6e-46
Identities = 99/170 (58%), Positives = 119/170 (70%), Gaps = 5/170 (2%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR L I IR +YR + K +RQR+ ALY IDKLALR GNE
Sbjct: 354 SRLKGEKDWKKYETARCLHKVIDKIRADYRADFKHKEMRIRQRAVALYFIDKLALRAGNE 413
Query: 191 KAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K EDEADTVGCCSLR EH+K P V FDFLGKDSIRY+NAV V K VF N++L
Sbjct: 414 KDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIRYQNAVSVPKRVFKNVKL 473
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
F +NK+ +D++F RL+ T LN YL++LM GL+AKVFRT+NAS TL E L+
Sbjct: 474 FLKNKKENDDLFDRLNTTVLNQYLRELMDGLTAKVFRTYNASRTLEEQLE 523
[101][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 186 bits (473), Expect = 7e-46
Identities = 102/186 (54%), Positives = 123/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG DH K+E AR+L I IR YR W +K VRQR+ ALY IDKLALR GNE
Sbjct: 715 SKLKGEKDHIKYETARRLDKFIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNE 774
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDF GKDSIRY N VEV+K VF NL+L
Sbjct: 775 KDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLEL 834
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+ D++F RL+ LN++LK+LM GL+AKVFRT+NAS TL L D +V
Sbjct: 835 FMENKKDGDDLFDRLNTQVLNEHLKELMDGLTAKVFRTYNASKTLQNQLDLLTDSNASVA 894
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 895 EKLLTY 900
[102][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 186 bits (472), Expect = 1e-45
Identities = 99/182 (54%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+LK+ I IR Y K + +K RQ + A YLIDKLALR G
Sbjct: 528 ASSSLKGQSDKEKYEKARKLKNYIKDIRATYTKDFVSKDITKRQIAVATYLIDKLALRAG 587
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE++ PP ++ FDFLGKDSIRYE VEV+ V+ ++ F
Sbjct: 588 NEKDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRV 647
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K SD++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E L D E V KV
Sbjct: 648 GKSGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVV 707
Query: 542 FY 547
Y
Sbjct: 708 VY 709
[103][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 186 bits (472), Expect = 1e-45
Identities = 105/192 (54%), Positives = 128/192 (66%), Gaps = 11/192 (5%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG SD KFE AR+LK I IRK+Y K ++ E RQR+TA+YLID+LALRVG
Sbjct: 624 ASSAVKGRSDMKKFEVARKLKDHIEKIRKKYLKELGSEELEERQRATAIYLIDRLALRVG 683
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK ED ADTVGCCSLRVEH+ P +V+ DFLGKDS+RY N V+VD VF NL F
Sbjct: 684 NEKDEDTADTVGCCSLRVEHVTLKEPASVTLDFLGKDSMRYHNTVDVDPRVFKNLSEFMY 743
Query: 365 N-------KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE- 520
K+P +++F +L+ +SLN YLK M LSAKVFRT+NAS+TL + L P
Sbjct: 744 KGGNKKAPKKPENDLFDQLTTSSLNKYLKGFMENLSAKVFRTYNASLTLEKELAKMPESL 803
Query: 521 ---TVTDKVAFY 547
T +KV FY
Sbjct: 804 IKATADEKVLFY 815
[104][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 186 bits (472), Expect = 1e-45
Identities = 103/183 (56%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+YRKG + RQR+TA+YLID+ ALR G
Sbjct: 498 ANSDIKGQSDFKKFEKARELKKHIDRIRKDYRKGLKDELMANRQRATAVYLIDQFALRAG 557
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 558 NEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 617
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QGDPGETVTDKV 538
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A L Q + T+ +KV
Sbjct: 618 APKKDGDEIFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMATLLRQMNATGTIHEKV 677
Query: 539 AFY 547
Y
Sbjct: 678 KQY 680
[105][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 186 bits (472), Expect = 1e-45
Identities = 103/183 (56%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+YRKG + RQR+TA+YLID+ ALR G
Sbjct: 498 ANSDIKGQSDFKKFEKARELKKHIDRIRKDYRKGLKDELMANRQRATAVYLIDQFALRAG 557
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 558 NEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 617
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QGDPGETVTDKV 538
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A L Q + T+ +KV
Sbjct: 618 APKKDGDEIFDRLTTSALNKHLSGYMAGLTAKVFRTYNASYTMATLLRQMNATGTIHEKV 677
Query: 539 AFY 547
Y
Sbjct: 678 KQY 680
[106][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 186 bits (472), Expect = 1e-45
Identities = 95/182 (52%), Positives = 128/182 (70%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG +D KFE AR LK+CI IRK Y+K + + E RQ + ALYLID LALRVGNE
Sbjct: 527 SKIKGQADRKKFEVARGLKNCIGDIRKGYQKSFNDESTEKRQLAVALYLIDFLALRVGNE 586
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K ED+ADTVGCCSLRVEH+K T++ DFLGKDS+RY N V++ + + L+ F + K
Sbjct: 587 KGEDQADTVGCCSLRVEHIKLESNNTITLDFLGKDSMRYLNTVQIREDAYKVLKTFVKGK 646
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL---AECLQGDPGETVTDKVA 541
+P+D +F L+VT LN++LK+ M GLSAKVFRT+NAS+TL + + +++ +K+
Sbjct: 647 KPTDLLFDSLTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKELDKMDTKEFQSIDEKIL 706
Query: 542 FY 547
FY
Sbjct: 707 FY 708
[107][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 186 bits (471), Expect = 1e-45
Identities = 103/189 (54%), Positives = 125/189 (66%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LKSC+ +IR +YR ++ RQR+ ALY IDKLALR G
Sbjct: 297 ANSKLKGEKDWEKYEVARKLKSCVDNIRSQYRSDLKSRQMSTRQRAVALYFIDKLALRAG 356
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+ V FDFLGKDSIRY N V V K VF N
Sbjct: 357 NEKEEGETADTVGCCSLRVEHITLHEQMDGKEYVVEFDFLGKDSIRYYNKVPVIKKVFKN 416
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
L+LF NKQP D +F RL + LN +L LMPGL+AKVFRT+NAS+TL E L+ + +
Sbjct: 417 LKLFLENKQPGDELFDRLYTSMLNKHLSSLMPGLTAKVFRTYNASITLQEQLKELTNKSD 476
Query: 521 TVTDKVAFY 547
+V +K+ Y
Sbjct: 477 SVAEKLLSY 485
[108][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 185 bits (470), Expect = 2e-45
Identities = 98/170 (57%), Positives = 118/170 (69%), Gaps = 6/170 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR Y++ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 452 SRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNE 511
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 512 KEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 571
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS+TL + L
Sbjct: 572 LFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQL 621
[109][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 185 bits (470), Expect = 2e-45
Identities = 100/182 (54%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFEKAR+LK + IR Y + + + V QR+ A+Y ID+LALRVGNE
Sbjct: 574 SSVKGQSDMVKFEKARKLKDKVDDIRASYMEDFKSNDLHVAQRAVAMY-IDRLALRVGNE 632
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K EDEADTVGCCSLRVEH++ P V FDFLGKDSIRY+N V V V+ LQ F R K
Sbjct: 633 KGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTRRK 692
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
P +IF +L+ T LND+LK M GLSAKVFRT+NAS+TL + DP + DK+A
Sbjct: 693 SPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLA 752
Query: 542 FY 547
++
Sbjct: 753 YF 754
[110][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 185 bits (470), Expect = 2e-45
Identities = 99/183 (54%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IR++YR+ ++ RQR+TA+YLID+ ALR G
Sbjct: 480 ANSDIKGQSDFKKFEKARELKKHIDRIRQDYRRELKSEKMVDRQRATAIYLIDQFALRAG 539
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ +H+ PP TV FDFLGKDSIR+ + V+VD VF NL++F +
Sbjct: 540 NEKGEDEADTVGCCSLKFQHITLRPPETVIFDFLGKDSIRFYDEVKVDAQVFKNLKIFKK 599
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKV 538
K D+IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+ T+ +KV
Sbjct: 600 EPKTVGDDIFDRLTTSALNKHLTSYMPGLTAKVFRTYNASYTMARLLKSLKATGTIQEKV 659
Query: 539 AFY 547
Y
Sbjct: 660 KAY 662
[111][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 185 bits (470), Expect = 2e-45
Identities = 98/167 (58%), Positives = 118/167 (70%), Gaps = 1/167 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+LK I SIRK+YR +K RQ++ A+YLID ALR G
Sbjct: 393 ANSSLKGQSDFKKFEKARELKKYIDSIRKDYRTNLKSKLMLERQKAVAIYLIDVFALRAG 452
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK++DEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEVDK VF NL +F R
Sbjct: 453 GEKSDDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLAIFKR 512
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
K+P D +F RL LN +L+ MPGL+AKVFRT+NAS T+ + L
Sbjct: 513 APKKPGDQLFDRLDPPILNKHLQNYMPGLTAKVFRTYNASKTMQDQL 559
[112][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 185 bits (470), Expect = 2e-45
Identities = 98/170 (57%), Positives = 118/170 (69%), Gaps = 6/170 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR Y++ W +K +VRQR+ ALY IDKLALR GNE
Sbjct: 489 SRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNE 548
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ V FDF GKDSIRY N V V+K VF NLQ
Sbjct: 549 KEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEKRVFKNLQ 608
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
LF NKQP D++F RL+ + LN +L+ LM GL+AKVFRT+NAS+TL + L
Sbjct: 609 LFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQL 658
[113][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 185 bits (469), Expect = 2e-45
Identities = 101/186 (54%), Positives = 125/186 (67%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+L I IR+ Y W ++ VRQRS ALY IDKLALR GNE
Sbjct: 417 SKLKGEKDWQKYETARRLAKSIDKIRENYINDWKSREMHVRQRSVALYFIDKLALRAGNE 476
Query: 191 KAEDEADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ED+ADTVGCCSLRVEH++ V FDFLGKDSIRY N V V+K VF NL++
Sbjct: 477 KDEDQADTVGCCSLRVEHIQLHEEFNDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLKI 536
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVT 529
F NK+ SD++F RL+ + LN +L +LM GL+AKVFRTFNAS TL + L+ DP +V
Sbjct: 537 FMENKKGSDDLFDRLNTSILNQHLHELMDGLTAKVFRTFNASWTLQQQLEKLTDPDVSVA 596
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 597 EKILQY 602
[114][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 184 bits (468), Expect = 3e-45
Identities = 97/182 (53%), Positives = 128/182 (70%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+LK I +IR Y K +A+K RQ + A YLIDKLALR G
Sbjct: 530 ASSSLKGQSDKEKYEKARKLKDYIHNIRTAYTKDFASKDITKRQIAVATYLIDKLALRAG 589
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSIRYEN VEV+ V+ ++ F
Sbjct: 590 NEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTVEVELPVYKAIRQFQV 649
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P+D++F L + LN +LK+LMPGL+AKVFRT+NAS+TL E L + + V +K
Sbjct: 650 AKKPTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKFV 709
Query: 542 FY 547
Y
Sbjct: 710 IY 711
[115][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 184 bits (467), Expect = 4e-45
Identities = 100/173 (57%), Positives = 117/173 (67%), Gaps = 6/173 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LKSC+ +IR +YR ++ RQR+ ALY IDKLALR G
Sbjct: 307 ANSKLKGEKDWEKYEVARKLKSCVDNIRSQYRSDLKSRQMSTRQRAVALYFIDKLALRAG 366
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+ V FDFLGKDSIRY N V V K VF N
Sbjct: 367 NEKEEGETADTVGCCSLRVEHITLHEQMDGKEYVVEFDFLGKDSIRYYNKVPVIKKVFKN 426
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
L+LF NKQP D +F RL + LN +L LMPGL+AKVFRT+NAS+TL E L+
Sbjct: 427 LKLFLENKQPGDELFDRLYTSMLNKHLSSLMPGLTAKVFRTYNASITLQEQLK 479
[116][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 184 bits (467), Expect = 4e-45
Identities = 94/182 (51%), Positives = 127/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG SD K+EK+R+LK + IR Y K + +K K +Q + A YLIDKLALR G
Sbjct: 586 ASSALKGQSDKEKYEKSRKLKHHVHKIRDTYTKDFRSKDKTKKQIAVATYLIDKLALRAG 645
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCC+L+V+++ PP + FDFLGKDSIRY N VEV+ V+ ++ F
Sbjct: 646 NEKDEDEAETVGCCTLKVDNVTCVPPNKLQFDFLGKDSIRYFNTVEVELLVYKAIEEFRA 705
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P ++F +L T LN +LK LMPGL+AKVFRT+NAS+TL + L + + T+ +K+A
Sbjct: 706 GKKPGQDLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIA 765
Query: 542 FY 547
Y
Sbjct: 766 VY 767
[117][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 184 bits (467), Expect = 4e-45
Identities = 94/182 (51%), Positives = 127/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG SD K+EK+R+LK + IR Y K + +K K +Q + A YLIDKLALR G
Sbjct: 586 ASSALKGQSDKEKYEKSRKLKHHVHKIRDTYTKDFRSKDKTKKQIAVATYLIDKLALRAG 645
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCC+L+V+++ PP + FDFLGKDSIRY N VEV+ V+ ++ F
Sbjct: 646 NEKDEDEAETVGCCTLKVDNVTCVPPNKLQFDFLGKDSIRYFNTVEVELLVYKAIEEFRA 705
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P ++F +L T LN +LK LMPGL+AKVFRT+NAS+TL + L + + T+ +K+A
Sbjct: 706 GKKPGQDLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIA 765
Query: 542 FY 547
Y
Sbjct: 766 VY 767
[118][TOP]
>UniRef100_Q5BXE0 SJCHGC03473 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BXE0_SCHJA
Length = 238
Score = 184 bits (467), Expect = 4e-45
Identities = 97/170 (57%), Positives = 119/170 (70%), Gaps = 5/170 (2%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR L I IR +YR + K +RQR+ ALY IDKLALR GNE
Sbjct: 5 SRLKGEKDWKKYETARCLHKVIDKIRADYRADFKHKEMRIRQRAVALYFIDKLALRAGNE 64
Query: 191 KAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K EDEADTVGCCSLR EH+K P V FDFLGKDSIRY+N+V V K VF N++L
Sbjct: 65 KDEDEADTVGCCSLRYEHIKLHEELNGQPYVVEFDFLGKDSIRYQNSVSVPKRVFKNVKL 124
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
F +NK+ +D++F RL+ + LN YL++LM GL+AKVFRT+NAS TL E L+
Sbjct: 125 FLKNKKENDDLFDRLNTSVLNQYLRELMDGLTAKVFRTYNASRTLEEQLE 174
[119][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 184 bits (467), Expect = 4e-45
Identities = 98/183 (53%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A + KG +D K+E AR+LK + IR++Y + +K RQR+TALY IDKLALR G
Sbjct: 2083 ADTHIKGRNDWKKYETARKLKEHVDKIRRDYTRDLKSKLMFERQRATALYFIDKLALRAG 2142
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
EK AE++ADTVGCCSLRVEHL+ P + FDFLGKDSIRY+N V+VD V+ N+ F
Sbjct: 2143 GEKDAEEQADTVGCCSLRVEHLELLPGDELVFDFLGKDSIRYQNQVKVDHQVWKNVGHFK 2202
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP-GETVTDKV 538
++K+P D +F RL LN+YL+ LM GL+AKVFRT+NAS+TL + L+ P G TV +K+
Sbjct: 2203 KSKEPGDELFDRLRTQQLNEYLQSLMDGLTAKVFRTYNASITLQDQLKSTPAGGTVEEKL 2262
Query: 539 AFY 547
Y
Sbjct: 2263 LAY 2265
[120][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 184 bits (467), Expect = 4e-45
Identities = 100/170 (58%), Positives = 117/170 (68%), Gaps = 6/170 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D+ KFE AR+LK + SIR+ Y K +K VRQR+ ALY IDKLALR GNE
Sbjct: 429 SKIKGEKDYEKFETARRLKDIVGSIRENYTKDLKSKEMRVRQRAVALYFIDKLALRAGNE 488
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K DEA DTVGCCSLR EH++ V FDFLGKDSIRY N V V+K VF NL+
Sbjct: 489 KDVDEAADTVGCCSLRCEHIQLHEKLDDNDYVVEFDFLGKDSIRYYNKVPVEKRVFKNLK 548
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
LF NK SD++F RL SLN YL+ LMPGL+AKVFRT+NAS+TL + L
Sbjct: 549 LFMENKSGSDDLFDRLDTASLNKYLQSLMPGLTAKVFRTYNASITLQQQL 598
[121][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 184 bits (467), Expect = 4e-45
Identities = 96/168 (57%), Positives = 124/168 (73%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK IA IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 464 ANSDVKGQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAG 523
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 524 NEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 583
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E L+
Sbjct: 584 PPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLK 631
[122][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 184 bits (467), Expect = 4e-45
Identities = 96/168 (57%), Positives = 124/168 (73%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK IA IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 464 ANSDVKGQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAG 523
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 524 NEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 583
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E L+
Sbjct: 584 PPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLK 631
[123][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 184 bits (467), Expect = 4e-45
Identities = 96/168 (57%), Positives = 124/168 (73%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK IA IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 464 ANSDVKGQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAG 523
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 524 NEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 583
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L Q MPGL+AKVFRT+NAS T++E L+
Sbjct: 584 PPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLK 631
[124][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 184 bits (466), Expect = 5e-45
Identities = 97/183 (53%), Positives = 118/183 (64%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS KG SD KFEKAR+LK I IR +Y + K RQR+TA+Y IDKLALR G
Sbjct: 475 AGSRLKGQSDMQKFEKARELKDHIEKIRADYTEDLRNKVMAHRQRATAMYFIDKLALRAG 534
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSLR EH+ PP + FDFLGKDSIRY V VD VF N+++F
Sbjct: 535 NEKGEDEADTVGCCSLRCEHVTLRPPNEIVFDFLGKDSIRYFKEVPVDAQVFKNIRIFKE 594
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD--PGETVTDKV 538
K+ DN+F R++ LN +L M GL+AKVFRT+NAS T L + T+ +K+
Sbjct: 595 GKELEDNLFDRVTTAGLNKHLTSYMKGLTAKVFRTYNASSTFQRLLDEEDLTNATIQEKI 654
Query: 539 AFY 547
Y
Sbjct: 655 NAY 657
[125][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 183 bits (465), Expect = 6e-45
Identities = 97/186 (52%), Positives = 123/186 (66%), Gaps = 7/186 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ SIRK Y + W ++ + RQR A+Y IDKLALR GNE
Sbjct: 269 SKLKGEKDWQKYETARRLKECVKSIRKRYMQDWKSREMKSRQRGVAIYFIDKLALRAGNE 328
Query: 191 KAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDKAVFFNLQL 355
K ++ ADTVGCCSLRVEH++ V FDFLGKDSIRY N V V+K VF NL+L
Sbjct: 329 KDDESADTVGCCSLRVEHIRLHKHLDGLDHVVEFDFLGKDSIRYYNKVPVEKQVFKNLKL 388
Query: 356 FCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE--TVT 529
F ++K P D++F R+S +LN L + M GL+AKVFRTFNAS TL + L + TV
Sbjct: 389 FIKHKDPEDDLFDRISTVNLNKALTESMSGLTAKVFRTFNASTTLQDQLNKLTSDDCTVE 448
Query: 530 DKVAFY 547
+K+ Y
Sbjct: 449 EKILSY 454
[126][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 183 bits (465), Expect = 6e-45
Identities = 101/183 (55%), Positives = 124/183 (67%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+LK I IRKEYR + +K RQ++ A+YLID ALR G
Sbjct: 311 ANSSLKGQSDFKKFEKARELKKHIDRIRKEYRNNFKSKLMVERQKAVAVYLIDVFALRAG 370
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK+E+EADTVGCCSLR EH+ PP TV FDFLGKDSIR+ V+VD VF NL LF +
Sbjct: 371 GEKSEEEADTVGCCSLRYEHITLKPPNTVIFDFLGKDSIRFYQEVQVDPKVFKNLALFKK 430
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP +F RL + LN +L+ M GL+AKVFRT+NAS T+ E L P E +V +K+
Sbjct: 431 PPKQPGHQLFDRLDPSLLNKFLQNYMTGLTAKVFRTYNASKTMQEQLDLIPNEGSVAEKL 490
Query: 539 AFY 547
Y
Sbjct: 491 LKY 493
[127][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 64 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 123
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 124 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 183
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 184 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 234
[128][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 171 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 230
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 231 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 290
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 291 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 341
[129][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 171 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 230
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 231 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 290
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 291 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 341
[130][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 64 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 123
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 124 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 183
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 184 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 234
[131][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 171 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 230
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 231 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 290
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 291 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 341
[132][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 183 bits (464), Expect = 8e-45
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 269 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 328
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 329 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 388
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK P D++F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 389 LFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 439
[133][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 182 bits (463), Expect = 1e-44
Identities = 94/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS+ KG+SD K+EKAR L I +IR Y K + AK ++RQ + A YLIDKLALR G
Sbjct: 181 AGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYLIDKLALRAG 240
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F
Sbjct: 241 NEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQA 300
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E L + + VT K+
Sbjct: 301 GKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIV 360
Query: 542 FY 547
Y
Sbjct: 361 VY 362
[134][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 182 bits (463), Expect = 1e-44
Identities = 94/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS+ KG+SD K+EKAR L I +IR Y K + AK ++RQ + A YLIDKLALR G
Sbjct: 63 AGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYLIDKLALRAG 122
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F
Sbjct: 123 NEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQA 182
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E L + + VT K+
Sbjct: 183 GKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIV 242
Query: 542 FY 547
Y
Sbjct: 243 VY 244
[135][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 182 bits (463), Expect = 1e-44
Identities = 97/182 (53%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
SA KG SD KFEKAR+LK+ + IR+ Y + + ++ QR+ A+Y IDKLALRVGNE
Sbjct: 262 SAIKGQSDMLKFEKARELKNHVDEIRRCYIEDFESRELMKAQRAVAMYFIDKLALRVGNE 321
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K DEADTVGCCSLRVEH++ P V FDFLGKDSIRYEN V V+ L+ F + K
Sbjct: 322 KGSDEADTVGCCSLRVEHIELKPDYVVKFDFLGKDSIRYENEAVVLPRVYELLRRFTKGK 381
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
+ D+IF ++ T LND+LK M GLSAKVFRT+NAS+TL + P +V DK+A
Sbjct: 382 KTGDDIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLA 441
Query: 542 FY 547
++
Sbjct: 442 YF 443
[136][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 182 bits (463), Expect = 1e-44
Identities = 97/182 (53%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
SA KG SD KFEKAR+LK+ + IR+ Y + + ++ QR+ A+Y IDKLALRVGNE
Sbjct: 262 SAIKGQSDMLKFEKARELKNHVDEIRRCYIEDFESRELMKAQRAVAMYFIDKLALRVGNE 321
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K DEADTVGCCSLRVEH++ P V FDFLGKDSIRYEN V V+ L+ F + K
Sbjct: 322 KGSDEADTVGCCSLRVEHIELKPDHVVKFDFLGKDSIRYENEAVVLPRVYELLRRFTKGK 381
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
+ D+IF ++ T LND+LK M GLSAKVFRT+NAS+TL + P +V DK+A
Sbjct: 382 KTGDDIFDMITPTVLNDHLKSFMAGLSAKVFRTYNASITLDRWFKEKPVPPSASVADKLA 441
Query: 542 FY 547
++
Sbjct: 442 YF 443
[137][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 182 bits (463), Expect = 1e-44
Identities = 98/180 (54%), Positives = 126/180 (70%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+L+ + +IRK+Y K ++ + RQ +TA+YLID ALR G
Sbjct: 444 ANSSVKGQSDFKKFEKARELRQHVDAIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAG 503
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK EDEADTVGCCSLR EHL PP V FDFLGKDSIR+ VEVDK VF NL++F +
Sbjct: 504 GEKGEDEADTVGCCSLRYEHLTLKPPNQVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKK 563
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ K+P D+IF R++ + +N L+ M GL+AKVFRT+NAS T+ + L P E T +KV
Sbjct: 564 DPKRPGDDIFDRINPSMVNKQLQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTAAEKV 623
[138][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 182 bits (463), Expect = 1e-44
Identities = 94/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
AGS+ KG+SD K+EKAR L I +IR Y K + AK ++RQ + A YLIDKLALR G
Sbjct: 583 AGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYLIDKLALRAG 642
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F
Sbjct: 643 NEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQA 702
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K +D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E L + + VT K+
Sbjct: 703 GKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIV 762
Query: 542 FY 547
Y
Sbjct: 763 VY 764
[139][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 182 bits (462), Expect = 1e-44
Identities = 98/183 (53%), Positives = 126/183 (68%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAA-KGKEVRQRSTALYLIDKLALRV 181
A S KG SD K+EKAR LK I IR Y K + K +Q + A YLIDKLALR
Sbjct: 596 ASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRA 655
Query: 182 GNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
GNEK +DEADTVGCC+L+VE+++ PP + FDFLGKDSIRY+N V+V+ AVF +Q F
Sbjct: 656 GNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFR 715
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD-PGETVTDKV 538
K+ S+++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL + L + G V +KV
Sbjct: 716 SGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKV 775
Query: 539 AFY 547
Y
Sbjct: 776 VVY 778
[140][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 182 bits (462), Expect = 1e-44
Identities = 102/188 (54%), Positives = 127/188 (67%), Gaps = 7/188 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+Y K ++ RQR+TA+YLID+LALR G
Sbjct: 505 AASDIKGQSDFKKFEKARELKKHIDRIRKDYTKELKSEVMADRQRATAMYLIDRLALRAG 564
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y V+ VF NL+LF
Sbjct: 565 NEKDTENEADTVGCCSLKYEHITLEPPNKVTFDFLGKDSIPYRETAHVEPQVFKNLKLFK 624
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGE--T 523
+ K D++F RL+ T LN +L MPGL+AKVFRT+NAS T++E L+G DP +
Sbjct: 625 KAPKTKGDDLFDRLTTTQLNKHLTNYMPGLTAKVFRTYNASFTMSELLKGLSKDPRSRGS 684
Query: 524 VTDKVAFY 547
V +KV Y
Sbjct: 685 VAEKVKLY 692
[141][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 182 bits (462), Expect = 1e-44
Identities = 96/171 (56%), Positives = 120/171 (70%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG + KFE AR+L+ + IR +YR W ++ + RQR+ ALY IDKLALR GNE
Sbjct: 269 SKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNE 328
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + EA DTVGCCSLRVEH++ P V FDFLGKD IRY N V V+K V+ NLQ
Sbjct: 329 KEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQ 388
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF +K P DN+F RL+ TSLN +L++LM GL+AKVFRT+NAS+TL E L+
Sbjct: 389 LFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLR 439
[142][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 182 bits (461), Expect = 2e-44
Identities = 101/196 (51%), Positives = 124/196 (63%), Gaps = 15/196 (7%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D+ K+E AR+LK I IR+ Y W +K +RQR+TALY IDKLALR G
Sbjct: 492 ASSKIKGSKDYEKYETARRLKKKIGGIRERYIADWKSKEMRIRQRATALYFIDKLALRAG 551
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT------------TVSFDFLGKDSIRYENAVEV 325
NEK DE ADTVGCCSLR EH+K V FDFLGKDSIRY N V V
Sbjct: 552 NEKDVDESADTVGCCSLRYEHIKLFESAKLQETDKKEKEFVVEFDFLGKDSIRYFNRVAV 611
Query: 326 DKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL- 502
+K VF NL+LF NK+ D++F RL +LN++L+ LM GL+ KVFRT+NAS+TL E L
Sbjct: 612 EKRVFKNLKLFMENKKAGDDLFDRLDTATLNEHLRSLMDGLTVKVFRTYNASITLQEQLI 671
Query: 503 -QGDPGETVTDKVAFY 547
+P + V K+ Y
Sbjct: 672 KLTNPDDNVAAKILSY 687
[143][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 182 bits (461), Expect = 2e-44
Identities = 98/180 (54%), Positives = 127/180 (70%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG+SD KFE AR+L+S + +IRK+Y K ++ + RQ ++A+YLID ALR G
Sbjct: 373 ASSSIKGVSDFKKFETARRLRSHVDAIRKDYTKMLKSELMQDRQMASAIYLIDVFALRAG 432
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F +
Sbjct: 433 GEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKK 492
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R++ T LN L+ M GL+AKVFRT+NAS T+ + L P E TV +KV
Sbjct: 493 APKQPGDDLFDRINPTMLNKQLQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKV 552
[144][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 181 bits (460), Expect = 2e-44
Identities = 93/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EK+R+LK I IR+ Y K + K RQ + A YLIDKLALR G
Sbjct: 591 ASSSLKGQSDKEKYEKSRKLKGHIQRIRENYTKDFKNKDVTRRQIAVATYLIDKLALRAG 650
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N VEV++ V+ ++ F
Sbjct: 651 NEKDDDEADTVGCCTLKVDNVTCMPPNKIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRA 710
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P + +F ++ T LN +LK LMPGL+AKVFRT+NAS+TL L + + T+ +K+A
Sbjct: 711 GKKPGEGLFDKIDTTRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTLLEKIA 770
Query: 542 FY 547
Y
Sbjct: 771 VY 772
[145][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 181 bits (460), Expect = 2e-44
Identities = 96/182 (52%), Positives = 127/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+LK I +IR Y K +A+K RQ + A YLIDKLALR G
Sbjct: 547 ASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDFASKDITKRQIAVATYLIDKLALRAG 606
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSIRYEN VEV+ V+ + F
Sbjct: 607 NEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTVEVELPVYKAIGHFQV 666
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+ +D++F L + LN +LK+LMPGL+AKVFRT+NAS+TL E L + + V +K+
Sbjct: 667 AKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKIV 726
Query: 542 FY 547
Y
Sbjct: 727 IY 728
[146][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 181 bits (460), Expect = 2e-44
Identities = 94/168 (55%), Positives = 122/168 (72%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 465 ANSDVKGQSDYKKFEKARELKKYIGKIRKDYQKNLKHELMVERQKATAVYLIDQFALRAG 524
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + V+VD VF NL++F +
Sbjct: 525 NEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEVDVDPQVFKNLKIFKK 584
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+AE L+
Sbjct: 585 APKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASHTMAELLK 632
[147][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 181 bits (459), Expect = 3e-44
Identities = 98/183 (53%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 591 ANSDVKGLSDYKKFEKARELKKHIDRIRKDYQKALKHELMVERQKATAVYLIDQFALRAG 650
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 651 NEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 710
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+ +V +KV
Sbjct: 711 PPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKDMKATGSVAEKV 770
Query: 539 AFY 547
Y
Sbjct: 771 KAY 773
[148][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 181 bits (459), Expect = 3e-44
Identities = 98/169 (57%), Positives = 124/169 (73%), Gaps = 2/169 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD+ KFEKAR+LK I IRK+Y + A+ RQR+TA+YLIDK ALR G
Sbjct: 500 AKSSIKGQSDYKKFEKARELKEHIDRIRKDYTQDLHAELMADRQRATAVYLIDKFALRAG 559
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK AE+EA+TVGCCSL+ EH+ PP TV FDFLGKDSIR+ + V VD VF NL++F
Sbjct: 560 NEKDAENEAETVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEVTVDPQVFKNLKIFK 619
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
+ K+ D+IF RL+ T LN +L MPGLSAKVFRT+NAS T+++ L+
Sbjct: 620 KAPKKNGDDIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMSDLLK 668
[149][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 181 bits (459), Expect = 3e-44
Identities = 98/183 (53%), Positives = 128/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 479 ANSDVKGLSDYKKFEKARELKKHIDRIRKDYQKALKHELMVERQKATAVYLIDQFALRAG 538
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 539 NEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 598
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+A L+ +V +KV
Sbjct: 599 PPKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTMATLLKDMKATGSVAEKV 658
Query: 539 AFY 547
Y
Sbjct: 659 KAY 661
[150][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 181 bits (458), Expect = 4e-44
Identities = 95/182 (52%), Positives = 121/182 (66%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I +IR Y K + K RQ + A YLIDKLALR G
Sbjct: 553 ASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAG 612
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE++ PP + FDFLGKDSIRY N VEV+ V+ + F
Sbjct: 613 NEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKT 672
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP-GETVTDKVA 541
K D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E L + G +K+
Sbjct: 673 GKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIV 732
Query: 542 FY 547
Y
Sbjct: 733 IY 734
[151][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 181 bits (458), Expect = 4e-44
Identities = 93/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EK+R+LK I IR+ Y K + K RQ + A YLIDKLALR G
Sbjct: 574 ASSSLKGQSDKEKYEKSRKLKGHIQRIRENYTKDFKNKDVTRRQIAVATYLIDKLALRAG 633
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N VEV++ V+ ++ F
Sbjct: 634 NEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRA 693
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P ++F ++ + LN +LK LMPGL+AKVFRT+NAS+TL L + + TV +K+A
Sbjct: 694 GKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTVLEKIA 753
Query: 542 FY 547
Y
Sbjct: 754 VY 755
[152][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 181 bits (458), Expect = 4e-44
Identities = 93/182 (51%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EK+R+LK I IR+ Y K + K RQ + A YLIDKLALR G
Sbjct: 244 ASSSLKGQSDKEKYEKSRKLKGHIQRIRENYTKDFKNKDVTRRQIAVATYLIDKLALRAG 303
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V+++ PP + FDFLGKDSIRY N VEV++ V+ ++ F
Sbjct: 304 NEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRA 363
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K+P ++F ++ + LN +LK LMPGL+AKVFRT+NAS+TL L + + TV +K+A
Sbjct: 364 GKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNASITLDGILHEETEDGTVLEKIA 423
Query: 542 FY 547
Y
Sbjct: 424 VY 425
[153][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 181 bits (458), Expect = 4e-44
Identities = 95/182 (52%), Positives = 121/182 (66%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I +IR Y K + K RQ + A YLIDKLALR G
Sbjct: 459 ASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAG 518
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE++ PP + FDFLGKDSIRY N VEV+ V+ + F
Sbjct: 519 NEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKT 578
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP-GETVTDKVA 541
K D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E L + G +K+
Sbjct: 579 GKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIV 638
Query: 542 FY 547
Y
Sbjct: 639 IY 640
[154][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 181 bits (458), Expect = 4e-44
Identities = 99/185 (53%), Positives = 129/185 (69%), Gaps = 4/185 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
+ S+ KG SDH KFEKAR+LK I IR++Y K ++ RQR+TA+YLID+ ALR G
Sbjct: 481 SSSSVKGKSDHMKFEKARELKKHIDRIRRDYGKDLKSETMADRQRATAMYLIDRFALRAG 540
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK AE+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ + V++ VF NL++F
Sbjct: 541 NEKNAEEEAETVGCCSLKFEHVTLKEPNTVVFDFLGKDSIRFFDEFTVERQVFKNLKIFK 600
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE--TVTD 532
+ K D+IF RL+ T LN +LK M GL+AKVFRT+NAS T++ LQ P E T+ +
Sbjct: 601 KPPKGEGDDIFDRLTTTQLNKHLKSYMDGLTAKVFRTYNASFTMSRLLQELPVEKATIAE 660
Query: 533 KVAFY 547
KV Y
Sbjct: 661 KVKLY 665
[155][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 181 bits (458), Expect = 4e-44
Identities = 99/183 (54%), Positives = 125/183 (68%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG+SD KFE AR+LK I IR +Y+K + RQ +TA YLID ALR G
Sbjct: 359 ANSSIKGISDMKKFETARRLKDHIERIRDDYKKMLKDPFMQNRQIATATYLIDVFALRAG 418
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK EDEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEVD+ VF NL++F +
Sbjct: 419 GEKGEDEADTVGCCSLRYEHVTLRPPNTVIFDFLGKDSIRFYQEVEVDRQVFKNLRIFKK 478
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R++ +LN +L+ M GL+AKVFRT+NAS T+ + + P E TV +KV
Sbjct: 479 EPKQPGDDLFDRITPATLNKHLQAYMKGLTAKVFRTYNASKTMQDQMDLIPNEGTVAEKV 538
Query: 539 AFY 547
Y
Sbjct: 539 MKY 541
[156][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 180 bits (457), Expect = 5e-44
Identities = 98/169 (57%), Positives = 123/169 (72%), Gaps = 2/169 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFEKAR+LK I IRK+Y + A+ RQR+TA+YLIDK ALR G
Sbjct: 501 AKSSIKGQSDFKKFEKARELKEHIDRIRKDYTQDLKAELMADRQRATAVYLIDKFALRAG 560
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK AE+EA+TVGCCSL+ EH+ PP TV FDFLGKDSIR+ + V VD VF NL++F
Sbjct: 561 NEKDAENEAETVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRFYDEVTVDPQVFKNLKIFK 620
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
+ K+ D+IF RL+ T LN +L MPGLSAKVFRT+NAS T+++ L+
Sbjct: 621 KAPKKNGDDIFDRLNTTQLNKHLTNYMPGLSAKVFRTYNASWTMSDLLK 669
[157][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 180 bits (456), Expect = 7e-44
Identities = 100/189 (52%), Positives = 125/189 (66%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LK+C+ +IR +Y++ +K RQR+ ALY IDKLALR G
Sbjct: 197 ANSKLKGEKDWEKYEVARKLKTCVDAIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAG 256
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+ V FDFLGKD IRY N V V K VF N
Sbjct: 257 NEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCIRYYNKVPVTKRVFKN 316
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
L+LF NKQ D++F RL+ SLN +L LMPGL+AKVFRT+NAS+TL + L+ + +
Sbjct: 317 LKLFMENKQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKD 376
Query: 521 TVTDKVAFY 547
V +K+ Y
Sbjct: 377 NVPEKLLSY 385
[158][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 180 bits (456), Expect = 7e-44
Identities = 100/189 (52%), Positives = 125/189 (66%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LK+C+ +IR +Y++ +K RQR+ ALY IDKLALR G
Sbjct: 275 ANSKLKGEKDWEKYEVARKLKTCVDAIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAG 334
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+ V FDFLGKD IRY N V V K VF N
Sbjct: 335 NEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCIRYYNKVPVTKRVFKN 394
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
L+LF NKQ D++F RL+ SLN +L LMPGL+AKVFRT+NAS+TL + L+ + +
Sbjct: 395 LKLFMENKQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKD 454
Query: 521 TVTDKVAFY 547
V +K+ Y
Sbjct: 455 NVPEKLLSY 463
[159][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 180 bits (456), Expect = 7e-44
Identities = 100/183 (54%), Positives = 122/183 (66%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KGMSD KFEKARQL+ I +IR +Y K +K RQ + A Y ID ALR G
Sbjct: 350 ANSSLKGMSDFKKFEKARQLRGFIDAIRADYTKNLKSKVMLERQIAVACYFIDVFALRAG 409
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EKA+DEADTVGCCSLR EH+ PP TV FDFLGKDSIR+ VEV K VF NL +F +
Sbjct: 410 GEKADDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVTKQVFKNLTIFKK 469
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
K+P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ + L P E TV +K+
Sbjct: 470 PPKKPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKM 529
Query: 539 AFY 547
Y
Sbjct: 530 LKY 532
[160][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 180 bits (456), Expect = 7e-44
Identities = 98/184 (53%), Positives = 125/184 (67%), Gaps = 3/184 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+Y+K RQ++TA+YLID+ ALR G
Sbjct: 456 ANSDVKGQSDFKKFEKARELKKHIEKIRKDYQKNLKHDMMVERQKATAVYLIDQFALRAG 515
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP TV FDFLGKDSIR+ + V+VD VF NL++F +
Sbjct: 516 NEKGEDEAETVGCCSLKYENVTLKPPNTVVFDFLGKDSIRFYDEVQVDLQVFKNLKIFKK 575
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--QGDPGETVTDK 535
K+ D IF RL+ ++LN +L MPGL+AKVFRT+NAS T+ L G T+ +K
Sbjct: 576 APKKNGDEIFDRLTTSALNKHLANYMPGLTAKVFRTYNASYTMGCVLNEMNASGGTIAEK 635
Query: 536 VAFY 547
V Y
Sbjct: 636 VKAY 639
[161][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 179 bits (455), Expect = 9e-44
Identities = 97/171 (56%), Positives = 117/171 (68%), Gaps = 6/171 (3%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK + IR +YR W ++ + RQ + ALY IDKLALR GNE
Sbjct: 323 SKLKGEKDWQKYEVARRLKGVVDEIRSQYRADWKSREMKKRQCAVALYFIDKLALRAGNE 382
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH++ P V DFLGKDSIRY N V V+K V+ NLQ
Sbjct: 383 KEEGETADTVGCCSLRVEHIQLYPEADGCQHVVELDFLGKDSIRYYNRVPVEKPVYKNLQ 442
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
LF NK D++F RL+ TSLN +L+ LM GL+AKVFRT+NASVTL E L+
Sbjct: 443 LFMENKSRGDDLFDRLTTTSLNKHLQDLMDGLTAKVFRTYNASVTLQEQLR 493
[162][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 179 bits (455), Expect = 9e-44
Identities = 100/189 (52%), Positives = 125/189 (66%), Gaps = 8/189 (4%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LKSC+ +IR +Y ++ RQR+ ALY IDKLALR G
Sbjct: 286 ANSKLKGEKDWEKYEVARKLKSCVDNIRNQYLMDLKSREMCTRQRAVALYFIDKLALRAG 345
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFN 346
NEK E E ADTVGCCSLRVEH+ V FDFLGKDSIRY N V V K VF N
Sbjct: 346 NEKEEGETADTVGCCSLRVEHITLHDTLDASECVVEFDFLGKDSIRYYNKVPVIKKVFKN 405
Query: 347 LQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGE 520
L+LF +KQP D +F RL+ + LN +L LMPGL+AKVFRT+NAS+TL + L+ + +
Sbjct: 406 LKLFMEDKQPGDELFDRLNTSLLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELTNESD 465
Query: 521 TVTDKVAFY 547
+V +K+ Y
Sbjct: 466 SVAEKLLSY 474
[163][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 179 bits (454), Expect = 1e-43
Identities = 93/182 (51%), Positives = 124/182 (68%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR LK I +IR Y K + +K +Q + A YLIDKLALR G
Sbjct: 557 ASSSLKGQSDKEKYEKARMLKDYIGNIRAYYTKDFTSKDITKQQIAVATYLIDKLALRAG 616
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+VE++ P + F+FLGKDSI+YEN VEV+ V+ + F +
Sbjct: 617 NEKDDDEADTVGCCTLKVENVTRETPNKLKFNFLGKDSIKYENTVEVELPVYNAILKFQK 676
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
+K P D++F +L LN +LK+LMPGL+AKVFRTFNAS+TL + L D + +K+
Sbjct: 677 DKGPGDDLFDKLDTNKLNAHLKELMPGLTAKVFRTFNASITLDDKLNKDTKDGDAAEKIV 736
Query: 542 FY 547
Y
Sbjct: 737 VY 738
[164][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 179 bits (454), Expect = 1e-43
Identities = 96/183 (52%), Positives = 125/183 (68%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAA-KGKEVRQRSTALYLIDKLALRV 181
A S KG SD K+EKAR LK I IR Y K + K +Q + A YLIDKLALR
Sbjct: 595 ASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRA 654
Query: 182 GNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
GNEK +DEADTVGCC+L+VE+++ PP + DF+GKDSIRY+N V+V+ AVF +Q F
Sbjct: 655 GNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFR 714
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD-PGETVTDKV 538
K+ S+++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL + L + G V +KV
Sbjct: 715 SGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKV 774
Query: 539 AFY 547
Y
Sbjct: 775 GVY 777
[165][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 179 bits (454), Expect = 1e-43
Identities = 101/194 (52%), Positives = 123/194 (63%), Gaps = 15/194 (7%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK I IR+ Y + +K VRQR+TALY IDKLALR GNE
Sbjct: 403 SKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNE 462
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT------------TVSFDFLGKDSIRYENAVEVDK 331
K DEA DTVGCCSLRVEH+K V FDFLGKDSIRY N V V+K
Sbjct: 463 KDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEK 522
Query: 332 AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--Q 505
V+ NL++F K PSD++F RL +LND+L+ LM GL+ KVFRT+NAS+TL E L
Sbjct: 523 RVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKL 582
Query: 506 GDPGETVTDKVAFY 547
+P + V K+ Y
Sbjct: 583 TNPKDNVAAKILSY 596
[166][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 179 bits (454), Expect = 1e-43
Identities = 101/194 (52%), Positives = 123/194 (63%), Gaps = 15/194 (7%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK I IR+ Y + +K VRQR+TALY IDKLALR GNE
Sbjct: 475 SKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNE 534
Query: 191 KAEDEA-DTVGCCSLRVEHLKFTPPT------------TVSFDFLGKDSIRYENAVEVDK 331
K DEA DTVGCCSLRVEH+K V FDFLGKDSIRY N V V+K
Sbjct: 535 KDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEK 594
Query: 332 AVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--Q 505
V+ NL++F K PSD++F RL +LND+L+ LM GL+ KVFRT+NAS+TL E L
Sbjct: 595 RVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKL 654
Query: 506 GDPGETVTDKVAFY 547
+P + V K+ Y
Sbjct: 655 TNPKDNVAAKILSY 668
[167][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 179 bits (453), Expect = 2e-43
Identities = 96/183 (52%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 474 ANSDVKGQSDYKKFEKARELKKHIDKIRKDYKKNMKNELMVERQKATAVYLIDQFALRAG 533
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 534 NEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEVEVDAQVFKNLKIFKK 593
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++ L+ T+ +KV
Sbjct: 594 SPKKEGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMSTLLKDMKATGTIAEKV 653
Query: 539 AFY 547
Y
Sbjct: 654 KAY 656
[168][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 179 bits (453), Expect = 2e-43
Identities = 96/183 (52%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 474 ANSDVKGQSDYKKFEKARELKKHIDKIRKDYKKNMKNELMVERQKATAVYLIDQFALRAG 533
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 534 NEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEVEVDAQVFKNLKIFKK 593
Query: 365 N-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++ L+ T+ +KV
Sbjct: 594 SPKKEGDEIFDRLTTSALNKHLSNYMQGLTAKVFRTYNASHTMSTLLKDMKATGTIAEKV 653
Query: 539 AFY 547
Y
Sbjct: 654 KAY 656
[169][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 178 bits (452), Expect = 2e-43
Identities = 99/183 (54%), Positives = 118/183 (64%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KGMSD KFEKAR LK I +R +Y+ + RQ + A YLID ALR G
Sbjct: 379 ANSTLKGMSDFKKFEKARMLKDHIDKVRTDYKSKMKSPKTLDRQMAVATYLIDVFALRAG 438
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EKA+DEADTVGCCSLR EH+ PP TV FDFLGKDSIRY VEVD VF NL++F R
Sbjct: 439 GEKADDEADTVGCCSLRYEHVTLRPPNTVVFDFLGKDSIRYYQEVEVDAQVFKNLKIFKR 498
Query: 365 NKQ-PSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
P +F RL + LN +L+ MPGL+AKVFRT+NAS T+ + L P E TV +K+
Sbjct: 499 PPSGPGHQLFDRLDPSILNKHLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKI 558
Query: 539 AFY 547
Y
Sbjct: 559 LRY 561
[170][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 178 bits (451), Expect = 3e-43
Identities = 95/174 (54%), Positives = 120/174 (68%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG SD K+EKAR+LK I IR +Y K + + ++ TA+YLID+LALRVG
Sbjct: 309 AASGFKGQSDWLKYEKARKLKKYIRGIRDDYTKKMKSSDDDEKELGTAVYLIDRLALRVG 368
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EADTVGCCSLRVEH+ F ++ DFLGKDSIRY N V+VD V+ NL+ C
Sbjct: 369 NEKNTEEEADTVGCCSLRVEHMTFEADNKITLDFLGKDSIRYLNTVQVDPLVYKNLKTLC 428
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL-AECLQGDPGE 520
+ ++P D IF + + +NDY KQ M LSAKVFRT+NAS+TL E + DP E
Sbjct: 429 KARKPEDMIF-SIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQELCKFDPEE 481
[171][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 178 bits (451), Expect = 3e-43
Identities = 99/185 (53%), Positives = 125/185 (67%), Gaps = 4/185 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG +D KFEKAR+LK I IR +Y K ++ RQR+TA+YLIDK ALR G
Sbjct: 463 ANSTVKGKADFKKFEKARELKKYIDRIRADYTKDLKSEVMADRQRATAMYLIDKFALRAG 522
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N VD+ VF NL++F
Sbjct: 523 NEKDTENEAETVGCCSLKYEHVTLREPNTVIFDFLGKDSIRFYNEFTVDRQVFKNLKMFK 582
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTD 532
+ K+ D+IF RL+ T LN +L MPGL+AKVFRT+NAS T+++ LQ TV +
Sbjct: 583 KPPKEDGDDIFDRLTTTQLNKHLSSYMPGLTAKVFRTYNASYTMSKLLQELKVTNATVHE 642
Query: 533 KVAFY 547
KV Y
Sbjct: 643 KVKLY 647
[172][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment) n=1
Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 177 bits (450), Expect = 3e-43
Identities = 100/203 (49%), Positives = 123/203 (60%), Gaps = 38/203 (18%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR+LK C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNE
Sbjct: 419 SRIKGEKDWQKYETARRLKKCVDRIRTQYREDWKSKEMRIRQRAVALYFIDKLALRAGNE 478
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K E E ADTVGCCSLRVEH+ P V FDFLGKDSIRY N + V+K VF NLQ
Sbjct: 479 KEEGETADTVGCCSLRVEHINLYPKLDDQEFVVEFDFLGKDSIRYYNKIPVEKRVFKNLQ 538
Query: 353 LFCRNKQPSDNIFHRLSV--------------------------------TSLNDYLKQL 436
LF NKQP D++F RL+V + LN +L++L
Sbjct: 539 LFLENKQPGDDLFDRLNVRISECRPVKIRCASAGAVSGCCTRPFFSLPQTSILNKHLQEL 598
Query: 437 MPGLSAKVFRTFNASVTLAECLQ 505
M GL+AKVFRT+NAS+TL + L+
Sbjct: 599 MDGLTAKVFRTYNASITLQQQLK 621
[173][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 177 bits (450), Expect = 3e-43
Identities = 95/174 (54%), Positives = 120/174 (68%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG SD K+EKAR+LK I IR +Y K + + ++ TA+YLID+LALRVG
Sbjct: 309 AASGFKGQSDWLKYEKARKLKKYIRGIRDDYTKKMKSTDDDEKELGTAVYLIDRLALRVG 368
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EADTVGCCSLRVEH+ F ++ DFLGKDSIRY N V+VD V+ NL+ C
Sbjct: 369 NEKNTEEEADTVGCCSLRVEHMTFEADNKITLDFLGKDSIRYLNTVQVDPLVYKNLKALC 428
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL-AECLQGDPGE 520
+ ++P D IF + + +NDY KQ M LSAKVFRT+NAS+TL E + DP E
Sbjct: 429 KARKPEDMIF-SIDPSKVNDYFKQFMQELSAKVFRTYNASITLEQELCKFDPEE 481
[174][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 177 bits (450), Expect = 3e-43
Identities = 96/179 (53%), Positives = 125/179 (69%), Gaps = 2/179 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFE AR+L+ + SIRK+Y K ++ + RQ +TA+YLID ALR G E
Sbjct: 377 SSVKGQSDFKKFETARKLRDHVDSIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGE 436
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRN- 367
K EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F ++
Sbjct: 437 KGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKKSP 496
Query: 368 KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ + + E TV +KVA
Sbjct: 497 KQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVA 555
[175][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 177 bits (450), Expect = 3e-43
Identities = 96/179 (53%), Positives = 125/179 (69%), Gaps = 2/179 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFE AR+L+ + SIRK+Y K ++ + RQ +TA+YLID ALR G E
Sbjct: 377 SSVKGQSDFKKFETARKLRDHVDSIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGE 436
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRN- 367
K EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F ++
Sbjct: 437 KGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKKSP 496
Query: 368 KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ + + E TV +KVA
Sbjct: 497 KQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVA 555
[176][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 176 bits (447), Expect = 8e-43
Identities = 95/183 (51%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+LK I +IR Y+K +K +Q + A YLIDKLALR G
Sbjct: 560 ASSSLKGQSDKEKYEKARKLKDYIHNIRAAYQKDLRSKDITKKQIAVATYLIDKLALRAG 619
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPT-TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK +DEADTVGCC+L+V +++ P + + FDFLGKDSIRYEN VEV V+ + F
Sbjct: 620 NEKDDDEADTVGCCTLKVANVECIPGSFNLKFDFLGKDSIRYENTVEVKPEVYEAIGTFQ 679
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
+ K+ +D++F +L T LN +LK+LMPGL+AKVFRT+NAS+TL E L + + V +KV
Sbjct: 680 KGKKQTDDLFDKLDTTKLNAHLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKV 739
Query: 539 AFY 547
Y
Sbjct: 740 VIY 742
[177][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 176 bits (447), Expect = 8e-43
Identities = 94/168 (55%), Positives = 119/168 (70%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 479 ANSDVKGQSDFKKFEKARELKKHIDRIRKDYQKSLKHELMVERQKATAVYLIDQFALRAG 538
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 539 NEKGEDEADTVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDAQVFKNLKIFKK 598
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T+A L+
Sbjct: 599 APKKEGDEIFDRLTTSALNKHLSTYMQGLTAKVFRTYNASYTMATLLK 646
[178][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 176 bits (446), Expect = 1e-42
Identities = 101/188 (53%), Positives = 123/188 (65%), Gaps = 7/188 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG SD KFEKAR+LK I IRK+Y K ++ RQR+TA+Y IDKLALR G
Sbjct: 496 ADSAIKGQSDFKKFEKARELKKHIDKIRKDYTKELKSEIMADRQRATAMYFIDKLALRAG 555
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y VD VF NL+LF
Sbjct: 556 NEKDTENEADTVGCCSLKYEHVTLEPPNKVTFDFLGKDSIPYRETAVVDAQVFKNLKLFK 615
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ---GDPGE--T 523
+ K D++F RL+ + LN +L M GL+AKVFRT+NAS T++ L DP T
Sbjct: 616 KAPKTTGDDLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMSTLLNKLGSDPRSRGT 675
Query: 524 VTDKVAFY 547
V +KV Y
Sbjct: 676 VAEKVKLY 683
[179][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 176 bits (446), Expect = 1e-42
Identities = 94/164 (57%), Positives = 118/164 (71%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+EKAR+LK + IR++Y K + RQ TA YLID LALRVG
Sbjct: 540 AQSKFKGQQDFLKYEKARKLKLHVDRIRQDYFKKLESTNSLDRQLGTATYLIDVLALRVG 599
Query: 185 NEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N V+V VF N+ F
Sbjct: 600 GEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNTVKVHPQVFKNVVGF 659
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
C+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 660 CKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[180][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 176 bits (446), Expect = 1e-42
Identities = 94/164 (57%), Positives = 118/164 (71%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+EKAR+LK + IR++Y K + RQ TA YLID LALRVG
Sbjct: 540 AQSKFKGQQDFLKYEKARKLKLHVDRIRQDYFKKLESTNSLDRQLGTATYLIDVLALRVG 599
Query: 185 NEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N V+V VF N+ F
Sbjct: 600 GEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNTVKVHPQVFKNVVGF 659
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
C+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 660 CKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[181][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 176 bits (446), Expect = 1e-42
Identities = 94/164 (57%), Positives = 118/164 (71%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+EKAR+LK + IR++Y K + RQ TA YLID LALRVG
Sbjct: 540 AQSKFKGQQDFLKYEKARKLKLHVDRIRQDYFKKLESTNSLDRQLGTATYLIDVLALRVG 599
Query: 185 NEK-AEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK ++EADTVGCCSLRVEHL F T V+FDFLGKDSIRY N V+V VF N+ F
Sbjct: 600 GEKDTDEEADTVGCCSLRVEHLTFDTEKQEVTFDFLGKDSIRYFNTVKVHPQVFKNVVGF 659
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
C+ K+P D++F +++ +LN++L+Q MPGLSAKVFRT+NAS+TL
Sbjct: 660 CKGKKPEDDVFDKINSAALNNHLRQFMPGLSAKVFRTYNASITL 703
[182][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 176 bits (446), Expect = 1e-42
Identities = 101/188 (53%), Positives = 123/188 (65%), Gaps = 7/188 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG SD KFEKAR+LK I IRK+Y K ++ RQR+TA+Y IDKLALR G
Sbjct: 495 ADSAIKGQSDFKKFEKARELKKHIDKIRKDYTKELKSEIMADRQRATAMYFIDKLALRAG 554
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EADTVGCCSL+ EH+ PP V+FDFLGKDSI Y VD VF NL+LF
Sbjct: 555 NEKDTENEADTVGCCSLKYEHVTLEPPNKVTFDFLGKDSIPYRETAVVDAQVFKNLKLFK 614
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ---GDPGE--T 523
+ K D++F RL+ + LN +L M GL+AKVFRT+NAS T++ L DP T
Sbjct: 615 KAPKTTGDDLFDRLTTSQLNKHLTSYMKGLTAKVFRTYNASFTMSTLLNKLGSDPRSRGT 674
Query: 524 VTDKVAFY 547
V +KV Y
Sbjct: 675 VAEKVKLY 682
[183][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 176 bits (445), Expect = 1e-42
Identities = 95/183 (51%), Positives = 123/183 (67%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAA-KGKEVRQRSTALYLIDKLALRV 181
A S KG SD K+EKAR LK I IR Y K + K +Q + A YLIDKLALR
Sbjct: 595 ASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRA 654
Query: 182 GNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
GNEK +DEADTVGCC+L+VE+++ PP + DF+GKDSIRY+N V+V+ AVF +Q F
Sbjct: 655 GNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFR 714
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGD-PGETVTDKV 538
K+ ++F RL + LN +LK+LMPGL+AKVFRT+NAS+TL + L + G V +KV
Sbjct: 715 SGKEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKV 774
Query: 539 AFY 547
Y
Sbjct: 775 GVY 777
[184][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 176 bits (445), Expect = 1e-42
Identities = 94/168 (55%), Positives = 117/168 (69%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG+ D K+ KAR+LK I IRK+Y + RQ TA YLID LALRVG
Sbjct: 333 AQSKFKGLHDFLKYSKARELKKHIMKIRKDYHGKMRSPEIVDRQLGTATYLIDFLALRVG 392
Query: 185 NEKAEDEADTVGCCSLRVEHLKF-TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
EK DEADTVGCCSLRVEH+KF P T++ DFLGKDSIRY + V +D+ NL FC
Sbjct: 393 GEKDADEADTVGCCSLRVEHIKFDRKPNTITLDFLGKDSIRYFHTVTLDEVACRNLSEFC 452
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
+ K+P+++IF +++ LNDYLK LM GL+AKVFRT+NAS+TL L+
Sbjct: 453 K-KKPTEDIFDKINTVKLNDYLKDLMTGLTAKVFRTYNASITLCRQLR 499
[185][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 175 bits (444), Expect = 2e-42
Identities = 95/179 (53%), Positives = 124/179 (69%), Gaps = 2/179 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFE AR+L+ + SIRK+Y K ++ + RQ +TA+YLID ALR G E
Sbjct: 375 SSVKGQSDFKKFETARKLRDHVDSIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGE 434
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRN- 367
K EDEADTVGCCSLR EH+ PP V FD LGKDSIR+ VEVDK VF NL++F ++
Sbjct: 435 KGEDEADTVGCCSLRYEHVTLKPPNKVIFDLLGKDSIRFYQEVEVDKQVFKNLRIFKKSP 494
Query: 368 KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ + + E TV +KVA
Sbjct: 495 KQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVA 553
[186][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 175 bits (443), Expect = 2e-42
Identities = 98/183 (53%), Positives = 120/183 (65%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ G SD KFEK+RQLK I +IRK+Y K K RQ++ A+YLID ALR G
Sbjct: 437 ANSSLNGQSDFKKFEKSRQLKYHIDAIRKDYNKNLKNKVMLERQKAVAIYLIDVFALRAG 496
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EKA+DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVD VF NL +F R
Sbjct: 497 GEKADDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEVEVDPQVFKNLTIFKR 556
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP +F RL + LN +L+ M GL+AKVFRT+NAS T+ + L E +V +K+
Sbjct: 557 PPKQPGHQLFDRLDPSVLNKHLQHYMQGLTAKVFRTYNASKTMQDQLDLIKNEGSVAEKI 616
Query: 539 AFY 547
Y
Sbjct: 617 LKY 619
[187][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 175 bits (443), Expect = 2e-42
Identities = 94/178 (52%), Positives = 124/178 (69%), Gaps = 2/178 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFE AR+L++ + IRK+Y K ++ + RQ +TA+YLID ALR G E
Sbjct: 374 SSVKGQSDFKKFETARKLRNYVDDIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGE 433
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRN- 367
K EDEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F ++
Sbjct: 434 KGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKKSP 493
Query: 368 KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ + + E TV +KV
Sbjct: 494 KQPGDDLFDRINPSLVNRQLQYYMKGLTAKVFRTYNASKTMQDQIDLIENEGTVAEKV 551
[188][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 174 bits (442), Expect = 3e-42
Identities = 94/182 (51%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG SD+AKFE AR+LK+ I IR+ Y K +++ + RQR+ A Y IDKLALRVG+E
Sbjct: 287 STLKGQSDYAKFETARELKNHIDDIRESYTKDFSSTDEMERQRAVATYFIDKLALRVGHE 346
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K E+EADTVGCCSLR EH++ P V FDFLGKDSIRY N V V V+ L F K
Sbjct: 347 KGEEEADTVGCCSLRKEHIELRPDNVVRFDFLGKDSIRYVNEVTVLPEVYKLLGSFI--K 404
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
+ IF +++ T+LN+YLK + LSAKVFRT+NAS+TL E + DP +++DK+
Sbjct: 405 RTDSEIFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEWFREKPVDPKASLSDKLV 464
Query: 542 FY 547
++
Sbjct: 465 YF 466
[189][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 174 bits (442), Expect = 3e-42
Identities = 94/182 (51%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG SD+AKFE AR+LK+ I IR+ Y K +++ + RQR+ A Y IDKLALRVG+E
Sbjct: 322 STLKGQSDYAKFETARELKNHIDDIRESYTKDFSSTDEMERQRAVATYFIDKLALRVGHE 381
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K E+EADTVGCCSLR EH++ P V FDFLGKDSIRY N V V V+ L F K
Sbjct: 382 KGEEEADTVGCCSLRKEHIELRPDNVVRFDFLGKDSIRYVNEVTVLPEVYKLLGSFI--K 439
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG---DPGETVTDKVA 541
+ IF +++ T+LN+YLK + LSAKVFRT+NAS+TL E + DP +++DK+
Sbjct: 440 RTDSEIFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEWFREKPVDPKASLSDKLV 499
Query: 542 FY 547
++
Sbjct: 500 YF 501
[190][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 174 bits (442), Expect = 3e-42
Identities = 98/180 (54%), Positives = 120/180 (66%), Gaps = 7/180 (3%)
Frame = +2
Query: 29 SDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAEDEA 208
SDH K+E AR+L I IR YR+ W +K VRQR+ ALY IDKLALRVGNEK +D+A
Sbjct: 302 SDHNKYETARRLHKFIDKIRATYREEWKSKDIFVRQRAVALYFIDKLALRVGNEKEKDQA 361
Query: 209 DTVGCCSLRVEHLK-----FTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQ 373
DTVGCCSLRVEH++ V+FDFLGKDSIRY VEV+ VF NL+LF ++K
Sbjct: 362 DTVGCCSLRVEHVQLHRRLMDKEYVVAFDFLGKDSIRYYKTVEVEPRVFNNLKLFVKDKG 421
Query: 374 PSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
S +F L+ LND+LK LM GL+ KVFRT+NAS+TL L D TV +K+ Y
Sbjct: 422 KSYYVFDCLNAHELNDHLKNLMIGLTTKVFRTYNASLTLQNQLDELTDEEATVAEKLLVY 481
[191][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 174 bits (442), Expect = 3e-42
Identities = 92/168 (54%), Positives = 120/168 (71%), Gaps = 1/168 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+Y+K + RQ++TA+YLID+ ALR G
Sbjct: 477 ANSDVKGQSDYKKFEKARELKHHIGRIRKDYQKNLKHELMVERQKATAVYLIDQFALRAG 536
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEA+TVGCCSL+ E++ PP V FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 537 NEKGEDEAETVGCCSLKYENVTLKPPNKVVFDFLGKDSIRFYDEVEVDAQVFKNLKIFKK 596
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ D IF RL+ ++LN +L M GL+AKVFRT+NAS T++ L+
Sbjct: 597 APKKEGDEIFDRLTTSALNKHLSAYMQGLTAKVFRTYNASHTMSTLLK 644
[192][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 174 bits (442), Expect = 3e-42
Identities = 94/188 (50%), Positives = 126/188 (67%), Gaps = 7/188 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKE-YRKGWAAKGKEVRQRSTALYLIDKLALRV 181
A S+ KG K+EK+R+LK I IR Y K +A+K + RQ + A YLIDKLALR
Sbjct: 432 ASSSLKGKVTREKYEKSRKLKDYIEGIRAAAYTKDFASKDSKKRQIAVATYLIDKLALRA 491
Query: 182 GNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
GNEK +DEADTVGCC+L+VE+++ P + FDFLGKDSIRY+N VEV+ VF ++ F
Sbjct: 492 GNEKDDDEADTVGCCTLKVENVETKRPNILKFDFLGKDSIRYQNEVEVEPRVFSAIEQFR 551
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL------QGDPGET 523
K+ D++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E + + G
Sbjct: 552 SGKEGGDDLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMVRCKLLSRETKGGD 611
Query: 524 VTDKVAFY 547
V +KV Y
Sbjct: 612 VAEKVVVY 619
[193][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 174 bits (440), Expect = 5e-42
Identities = 94/169 (55%), Positives = 119/169 (70%), Gaps = 2/169 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A SA KG +D KFEKAR+LK I IR +Y + ++ RQR+TA+Y IDKLALR G
Sbjct: 494 ANSAVKGQADFKKFEKARELKKHIDRIRADYTRELRSEIMADRQRATAMYFIDKLALRAG 553
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EA+TVGCCSL+VE++ PP V DFLGKDSIR+E VEVD VF NL++F
Sbjct: 554 NEKDTENEAETVGCCSLKVENVSLQPPNKVFLDFLGKDSIRFEQEVEVDAQVFKNLKMFK 613
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
+ K D+IF RL+ + LN +L MPGL+AKVFRT+NAS T++ LQ
Sbjct: 614 KAPKVEGDDIFDRLTTSQLNKHLSSYMPGLTAKVFRTYNASYTMSTLLQ 662
[194][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 173 bits (439), Expect = 6e-42
Identities = 91/172 (52%), Positives = 110/172 (63%), Gaps = 6/172 (3%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FK SD AK+EKAR+LK I +RK Y + W + + RQ A+Y IDKLALR G
Sbjct: 243 ATSTFKADSDLAKYEKARKLKEIIVDVRKNYERDWDSSDQRKRQMGVAMYFIDKLALRAG 302
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
+EK EDEADTVGCC+L+VE+++ V FDFLGKDSIRYEN VEVD V+ NL+ F R
Sbjct: 303 HEKDEDEADTVGCCTLKVENIEIMGDNKVKFDFLGKDSIRYENIVEVDPRVYKNLEKFKR 362
Query: 365 ------NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
KQ D +F LN LK +M GLS KVFRT+NAS+ L L
Sbjct: 363 IDHTGKRKQQGDQLFETFDAQDLNKELKNIMDGLSVKVFRTYNASIVLDRLL 414
[195][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 173 bits (439), Expect = 6e-42
Identities = 89/164 (54%), Positives = 114/164 (69%), Gaps = 2/164 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+ KAR+LK+ I IR +Y + +Q TA+YLID LALRVG
Sbjct: 552 AQSKFKGFHDFLKYNKARELKAYIQKIRDDYNTKMLSMDIYEKQLGTAVYLIDFLALRVG 611
Query: 185 NEKAEDEADTVGCCSLRVEHLKFT--PPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLF 358
EK DEADTVGCCSLRVEH+KF+ T++ DFLGKDSIRY N V ++ + NL F
Sbjct: 612 GEKDADEADTVGCCSLRVEHIKFSEKKQNTITLDFLGKDSIRYFNTVTLNDVAYDNLAKF 671
Query: 359 CRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
C K+ S+ IF++++ LN+YL++LM GLSAKVFRT+NAS+TL
Sbjct: 672 CHRKKASEEIFNKINTNKLNEYLRELMDGLSAKVFRTYNASITL 715
[196][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 173 bits (439), Expect = 6e-42
Identities = 93/178 (52%), Positives = 123/178 (69%), Gaps = 2/178 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S+ KG SD KFE AR+L++ + IRK+Y K ++ + RQ +TA+YLID ALR G E
Sbjct: 374 SSIKGQSDFKKFETARRLRNHVDEIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGE 433
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR-N 367
K +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F +
Sbjct: 434 KGDDEADTVGCCSLRYEHVTLKPPNKVVFDFLGKDSIRFYQEVEVDKQVFKNLRIFKKAP 493
Query: 368 KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R++ + +N L+ M GL+AKVFRT+NAS T+ + + E TV +KV
Sbjct: 494 KQPGDDLFDRINPSLVNKQLQNYMKGLTAKVFRTYNASKTMQDQIDLIENEGTVAEKV 551
[197][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 173 bits (438), Expect = 8e-42
Identities = 98/184 (53%), Positives = 122/184 (66%), Gaps = 8/184 (4%)
Frame = +2
Query: 20 KGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAE 199
KG D K+E AR+LK + IR +Y+ W + + RQ + ALY IDKLALR GNEK E
Sbjct: 264 KGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEE 323
Query: 200 DE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
E ADTVGCCSLRVEH++ P V DFLGKDSIRY+N V V+K VF NLQ F
Sbjct: 324 GETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFM 383
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDK 535
+K P D++F L+ +SLN +L+ LM GL+AKVFRT+NASVTL E L+ ++VT K
Sbjct: 384 EDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCK 443
Query: 536 VAFY 547
V Y
Sbjct: 444 VLAY 447
[198][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 173 bits (438), Expect = 8e-42
Identities = 98/184 (53%), Positives = 122/184 (66%), Gaps = 8/184 (4%)
Frame = +2
Query: 20 KGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAE 199
KG D K+E AR+LK + IR +Y+ W + + RQ + ALY IDKLALR GNEK E
Sbjct: 265 KGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEE 324
Query: 200 DE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
E ADTVGCCSLRVEH++ P V DFLGKDSIRY+N V V+K VF NLQ F
Sbjct: 325 GETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFM 384
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDK 535
+K P D++F L+ +SLN +L+ LM GL+AKVFRT+NASVTL E L+ ++VT K
Sbjct: 385 EDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCK 444
Query: 536 VAFY 547
V Y
Sbjct: 445 VLAY 448
[199][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
Length = 904
Score = 172 bits (437), Expect = 1e-41
Identities = 96/185 (51%), Positives = 124/185 (67%), Gaps = 4/185 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG +D+ KFEKAR+L IA IR +Y ++ RQR+TA+YLIDK ALR G
Sbjct: 493 ANSTVKGQADYKKFEKARELNKHIARIRADYTAELKSEIMAERQRATAMYLIDKFALRAG 552
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N V++ VF NL+LF
Sbjct: 553 NEKDTENEAETVGCCSLKFEHVTLREPNTVIFDFLGKDSIRFYNEFTVERQVFKNLKLFK 612
Query: 362 R-NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE--TVTD 532
+ K D+IF RL+ + LN +L MPGL+AKVFRT+NAS T++ LQ E T+ +
Sbjct: 613 KPPKADGDDIFDRLTTSQLNKHLSNYMPGLTAKVFRTYNASHTMSTLLQSLSVENRTMAE 672
Query: 533 KVAFY 547
K+ Y
Sbjct: 673 KIKLY 677
[200][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 172 bits (436), Expect = 1e-41
Identities = 96/180 (53%), Positives = 120/180 (66%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG+SD KFE +R+L+ I IRK+Y K + RQ +TA YLID ALR G
Sbjct: 384 ANSSIKGLSDFKKFETSRKLRYHIDEIRKDYTKMLKDPLMQNRQMATACYLIDIFALRAG 443
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEV+K VF NL++F +
Sbjct: 444 GEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEVEVEKQVFKNLRIFKK 503
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R+S LN + M GL+AKVFRT+NAS T+ + L P E TV +KV
Sbjct: 504 PPKQPGDDLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKV 563
[201][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 172 bits (436), Expect = 1e-41
Identities = 96/180 (53%), Positives = 120/180 (66%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG+SD KFE +R+L+ I IRK+Y K + RQ +TA YLID ALR G
Sbjct: 384 ANSSIKGLSDFKKFETSRKLRYHIDEIRKDYTKMLKDPLMQNRQMATACYLIDIFALRAG 443
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEV+K VF NL++F +
Sbjct: 444 GEKGDDEADTVGCCSLRYEHITLKPPNKVIFDFLGKDSIRFYQEVEVEKQVFKNLRIFKK 503
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R+S LN + M GL+AKVFRT+NAS T+ + L P E TV +KV
Sbjct: 504 PPKQPGDDLFDRISPPLLNKQFQNYMKGLTAKVFRTYNASKTMQDQLDLIPNEGTVAEKV 563
[202][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 171 bits (434), Expect = 2e-41
Identities = 97/180 (53%), Positives = 118/180 (65%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFE AR LK I +IR +Y K + RQ +TA YLID ALR G
Sbjct: 349 ANSSVKGQSDFKKFETARNLKFHIDAIRTDYTKLLKDPLMQNRQMATATYLIDVFALRAG 408
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F +
Sbjct: 409 GEKGDDEADTVGCCSLRYEHITLKPPNQVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKK 468
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R+S LN + M GL+AKVFRT+NAS T+ + + P E TV +KV
Sbjct: 469 PPKQPGDDLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKV 528
[203][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 171 bits (434), Expect = 2e-41
Identities = 97/180 (53%), Positives = 118/180 (65%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD KFE AR LK I +IR +Y K + RQ +TA YLID ALR G
Sbjct: 349 ANSSVKGQSDFKKFETARNLKFHIDAIRTDYTKLLKDPLMQNRQMATATYLIDVFALRAG 408
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +DEADTVGCCSLR EH+ PP V FDFLGKDSIR+ VEVDK VF NL++F +
Sbjct: 409 GEKGDDEADTVGCCSLRYEHITLKPPNQVIFDFLGKDSIRFYQEVEVDKQVFKNLRIFKK 468
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKV 538
KQP D++F R+S LN + M GL+AKVFRT+NAS T+ + + P E TV +KV
Sbjct: 469 PPKQPGDDLFDRISPPMLNKQFQGYMKGLTAKVFRTYNASKTMQDQIDLIPNEGTVAEKV 528
[204][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 171 bits (434), Expect = 2e-41
Identities = 92/168 (54%), Positives = 115/168 (68%), Gaps = 6/168 (3%)
Frame = +2
Query: 20 KGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAE 199
KG D K+E AR+LK + IR +Y+ W + + RQ + ALY IDKLALR GNEK E
Sbjct: 265 KGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEE 324
Query: 200 DE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
E ADTVGCCSLRVEH++ P V DFLGKDSIRY+N V V+K VF NLQ F
Sbjct: 325 GETADTVGCCSLRVEHVRLHTPADGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFM 384
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
+K P D++F L+ +SLN +L+ LM GL+AKVFRT+NAS+TL E L+
Sbjct: 385 EDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASITLQEQLR 432
[205][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 171 bits (432), Expect = 4e-41
Identities = 92/182 (50%), Positives = 121/182 (66%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ KG SD K+EKAR+L + I SIR Y K + K RQ + A YLIDKLALR G
Sbjct: 581 ASSSLKGQSDKEKYEKARKLHNHIGSIRAAYTKDFNNKDVTKRQIAVATYLIDKLALRAG 640
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK +DEADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F
Sbjct: 641 NEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQA 700
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVA 541
K +D++F L + LN +LK+LM GL+AKVFRT+NAS+TL L + + V +KV
Sbjct: 701 GKSKTDDLFDELDTSKLNTHLKELMAGLTAKVFRTYNASITLDLMLSKETRDGDVPEKVV 760
Query: 542 FY 547
Y
Sbjct: 761 VY 762
[206][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 171 bits (432), Expect = 4e-41
Identities = 94/185 (50%), Positives = 125/185 (67%), Gaps = 4/185 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG +D KFEKAR LK I IR +Y + ++ RQR+TA+YLID+ ALR G
Sbjct: 496 ANSTVKGQADFKKFEKARDLKKHIDRIRADYTRELKSEVMADRQRATAMYLIDRFALRAG 555
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFC 361
NEK E+EA+TVGCCSL+ EH+ P TV FDFLGKDSIR+ N VD+ VF NL++F
Sbjct: 556 NEKDTENEAETVGCCSLKFEHVTLREPNTVIFDFLGKDSIRFYNEFSVDRQVFKNLKVFK 615
Query: 362 RN-KQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE--TVTD 532
++ K+ D+IF RL+ + LN +L M GL+AKVFRT+NAS T+++ LQ E T+ +
Sbjct: 616 KSPKEDGDDIFDRLTTSQLNKHLSSYMTGLTAKVFRTYNASWTMSQLLQKLEVEDRTMAE 675
Query: 533 KVAFY 547
K+ Y
Sbjct: 676 KIKLY 680
[207][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 170 bits (431), Expect = 5e-41
Identities = 97/182 (53%), Positives = 117/182 (64%), Gaps = 15/182 (8%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDK------ 166
A S KG D K+E AR+LKSC+ +IR +Y ++ RQR+ ALY IDK
Sbjct: 265 ANSKLKGEKDWEKYEVARKLKSCVDNIRNQYLMDLKSREMCTRQRAVALYFIDKVGVTVV 324
Query: 167 ---LALRVGNEKAEDE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAV 319
LALR GNEK E E ADTVGCCSLRVEH+ V FDFLGKDSIRY N V
Sbjct: 325 ILKLALRAGNEKEEGETADTVGCCSLRVEHITLHDTLDASECVVEFDFLGKDSIRYYNKV 384
Query: 320 EVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAEC 499
V K VF NL+LF +KQP D +F RL+ + LN +L LMPGL+AKVFRT+NAS+TL +
Sbjct: 385 PVIKKVFKNLKLFMEDKQPGDELFDRLNTSLLNKHLSSLMPGLTAKVFRTYNASITLQQQ 444
Query: 500 LQ 505
L+
Sbjct: 445 LK 446
[208][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 170 bits (430), Expect = 7e-41
Identities = 98/198 (49%), Positives = 124/198 (62%), Gaps = 17/198 (8%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQ---------------- 136
A S+ KG SD K+EKAR+LK I IR Y K +++K RQ
Sbjct: 563 ASSSLKGQSDKEKYEKARKLKGYIEGIRTAYTKDFSSKDVTKRQIAVATYLIDKLALRAG 622
Query: 137 RSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENA 316
+ A YLIDKLALR GNEK +DEADTVGCC+L+VE+++ + DFL KDSIRY+
Sbjct: 623 NAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPRNNPLLKLDFLPKDSIRYQKR 682
Query: 317 VEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 496
VEV+ VF +Q F K+ SDN+F +L LN +LK+LMPGLSAKVFRT+NAS+TL E
Sbjct: 683 VEVEIPVFKAIQQFRSGKKGSDNLFDKLDTCKLNAHLKELMPGLSAKVFRTYNASITLDE 742
Query: 497 CLQGD-PGETVTDKVAFY 547
L + G V+ KVA Y
Sbjct: 743 MLNKETKGGDVSQKVAVY 760
[209][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 169 bits (427), Expect = 2e-40
Identities = 91/200 (45%), Positives = 123/200 (61%), Gaps = 33/200 (16%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+E AR+LKSC+ IRK+Y+ +K +Q TA+YLID LALRVG
Sbjct: 379 AQSKFKGYKDFLKYENARKLKSCVHKIRKDYQNKMKSKNIINKQLGTAVYLIDFLALRVG 438
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTT------------------------------- 268
EK ++EADTVGCCSLRVEH+ F+
Sbjct: 439 GEKDIDEEADTVGCCSLRVEHVSFSHNVIIKNENTNDENDNKISKIPLPKNLEDILEDDC 498
Query: 269 -VSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPG 445
V+ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +++ + LN+YLK++MP
Sbjct: 499 YVTLDFLGKDSIRYFNTVKIDKQAYINMIIFCKNKNKDEGVFDQITCSKLNEYLKEIMPT 558
Query: 446 LSAKVFRTFNASVTLAECLQ 505
LSAKVFRT+NAS+TL + L+
Sbjct: 559 LSAKVFRTYNASITLDQQLR 578
[210][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 167 bits (424), Expect = 4e-40
Identities = 90/200 (45%), Positives = 122/200 (61%), Gaps = 33/200 (16%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+E AR+LKSC+ IRK+Y+ K +Q TA+YLID LALRVG
Sbjct: 434 AQSKFKGYKDFLKYENARKLKSCVHKIRKDYQNKMKNKNIVNKQLGTAVYLIDFLALRVG 493
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTPPTTV------------------------------ 271
EK ++EADTVGCCSLRVEH+ F+ +
Sbjct: 494 GEKDIDEEADTVGCCSLRVEHVSFSHNVIIKNENTNDENDNKISKIPLPKNLEDILEDDC 553
Query: 272 --SFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPG 445
+ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +++ + LN+YLK++MP
Sbjct: 554 YITLDFLGKDSIRYFNTVKIDKQAYINMIIFCKNKNKDEGVFDQITCSKLNEYLKEIMPT 613
Query: 446 LSAKVFRTFNASVTLAECLQ 505
LSAKVFRT+NAS+TL + L+
Sbjct: 614 LSAKVFRTYNASITLDQQLR 633
[211][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 167 bits (423), Expect = 5e-40
Identities = 100/188 (53%), Positives = 119/188 (63%), Gaps = 9/188 (4%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S KG D K+E AR LKS + IR++Y + + VRQR+ ALY IDKLALR GNE
Sbjct: 149 SRVKGEKDWQKYEVARNLKSKVDRIREDYMRDLKSDEMMVRQRAVALYFIDKLALRAGNE 208
Query: 191 KAEDE-ADTVGCCSLRVEHLKFTPPTT-----VSFDFLGKDSIRYENAVEVDKAVFFNLQ 352
K + E ADTVGCCSLR EH+K V FDFLGKDSIRY N V V K VF NL
Sbjct: 209 KEDGESADTVGCCSLRCEHIKLHKHLDGKDFIVEFDFLGKDSIRYYNKVPVLKQVFKNLV 268
Query: 353 LFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL--QGDP-GET 523
LF NK+ D++F RL+ ++LN YL LM GL+AKVFRT+NAS+TL L DP E
Sbjct: 269 LFTENKEGPDDLFDRLNTSTLNKYLNSLMDGLTAKVFRTYNASITLLNQLLELTDPDDEN 328
Query: 524 VTDKVAFY 547
V K+ Y
Sbjct: 329 VASKILSY 336
[212][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 166 bits (419), Expect = 1e-39
Identities = 91/202 (45%), Positives = 123/202 (60%), Gaps = 35/202 (17%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FKG D K+E AR+LKSC+ IR++Y+ K +Q TA+YLID LALRVG
Sbjct: 382 AQSKFKGYKDLMKYENARKLKSCVHKIREDYKNKMKNKNIIDKQLGTAVYLIDFLALRVG 441
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTP------------------------PTT------- 268
EK ++EADTVGCCSLRVEH+ F PT
Sbjct: 442 GEKDIDEEADTVGCCSLRVEHISFAHDIPFKSVDSKEQKTNDEKVNKIPLPTNLESISSE 501
Query: 269 ---VSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLM 439
++ DFLGKDSIRY N V++DK + N+ +FC+NK + +F +++ + LN+YLK++M
Sbjct: 502 DCYITLDFLGKDSIRYFNTVKIDKQAYINIIIFCKNKNRDEGVFDQITCSKLNEYLKEIM 561
Query: 440 PGLSAKVFRTFNASVTLAECLQ 505
P LSAKVFRT+NAS+TL + L+
Sbjct: 562 PTLSAKVFRTYNASITLDQQLK 583
[213][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 164 bits (415), Expect = 4e-39
Identities = 84/167 (50%), Positives = 112/167 (67%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ K SD K+EKAR+LK + +IR++Y K + +Q + YL+DKLALR G
Sbjct: 325 ATSSIKAESDIQKYEKARKLKLAVDAIRRDYFKKMKSGSVLEQQLAVTTYLVDKLALRAG 384
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK +D ADTVG C+LRV H+ F PP+T+ FDFLGKDSIRY EVD VF +Q FC+
Sbjct: 385 GEKDDDLADTVGVCTLRVGHIDFLPPSTIKFDFLGKDSIRYLQEHEVDPLVFHAMQRFCK 444
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K+ +IF + T +N +L+ LMPGL+ KVFRT+NAS TL + L+
Sbjct: 445 GKKKDQDIFDHIDPTKVNKHLQTLMPGLTIKVFRTYNASYTLNKLLK 491
[214][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 164 bits (414), Expect = 5e-39
Identities = 88/182 (48%), Positives = 120/182 (65%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+ K SD K+EKAR+LK + +IR++Y K +Q + YL+DKLALR G
Sbjct: 378 AMSSIKAESDIQKYEKARKLKLAVDAIRRDYFKKMKTGDMLAKQLAVTTYLVDKLALRAG 437
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK ED ADTVG C+LRV H++F P+T+ DFLGKDSIRY EVD VF +Q FC+
Sbjct: 438 GEKDEDLADTVGVCTLRVGHVEFITPSTLKLDFLGKDSIRYLQEHEVDPLVFEAMQKFCK 497
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKVA 541
K+P ++IF ++ + +N +L+ LMPGL+ KVFRT+NAS L + L+ +P +TV K A
Sbjct: 498 GKKPDNDIFDQIDPSKVNKHLQTLMPGLTIKVFRTYNASFVLNKLLKDTNPRDTVPLKKA 557
Query: 542 FY 547
Y
Sbjct: 558 AY 559
[215][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 161 bits (408), Expect = 3e-38
Identities = 87/182 (47%), Positives = 120/182 (65%), Gaps = 18/182 (9%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+FKG SD +K+ KA +L I IR +Y+K +K E RQ +TA+++ID+LALRVG
Sbjct: 168 AQSSFKGKSDRSKYNKAAKLCGNIDKIRTDYKKNLTSKSLETRQLATAMWVIDRLALRVG 227
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTP------PTTVSFDFLGKDSIRYENAVEVDKA--- 334
EK ++EADTVGCCSLRVEHLKF P + +FLGKDS+ ++ ++ A
Sbjct: 228 GEKDTDEEADTVGCCSLRVEHLKFDPNNEGEDSKEIELEFLGKDSMLFKQTIDFGSALYT 287
Query: 335 --------VFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
V+ N QLFC+ K+P+D++F L+ T LN +LK +M GL+AKVFRT+NAS TL
Sbjct: 288 ENNGMGEQVYKNFQLFCKKKKPTDDVFSDLTPTILNAHLKSIMEGLTAKVFRTYNASKTL 347
Query: 491 AE 496
+
Sbjct: 348 QD 349
[216][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 159 bits (403), Expect = 1e-37
Identities = 96/183 (52%), Positives = 113/183 (61%), Gaps = 2/183 (1%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IRK+YRKG + RQR+TA+YLID+ ALR G
Sbjct: 500 ANSDIKGQSDYKKFEKARELKKHIDRIRKDYRKGLKDELTANRQRATAVYLIDQFALRAG 559
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP V FDFLGKDSIR+ + VEVD VF NL+ F +
Sbjct: 560 NEKGEDEADTVGCCSLKYEHVTLKPPNKVIFDFLGKDSIRFYDEVEVDHQVFKNLKFFKK 619
Query: 365 -NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QGDPGETVTDKV 538
K D IF RL+ VFRT+NAS T+A L Q TV +KV
Sbjct: 620 APKGEGDEIFDRLT------------------VFRTYNASYTMATLLKQMQATGTVHEKV 661
Query: 539 AFY 547
Y
Sbjct: 662 KQY 664
[217][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 159 bits (402), Expect = 1e-37
Identities = 88/172 (51%), Positives = 111/172 (64%), Gaps = 10/172 (5%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAK--------GKEVRQRSTALYLI 160
A S FKG D K+ KAR+LK+ I IR +Y +Q TA+YLI
Sbjct: 553 AQSKFKGFHDFLKYNKARELKAYIQKIRDDYNTKMLCMTIIYTITLDIYEKQLGTAVYLI 612
Query: 161 DKLALRVGNEKAEDEADTVGCCSLRVEHLKFT--PPTTVSFDFLGKDSIRYENAVEVDKA 334
D LALRVG EK DEADTVGCCSLRVEH+KF+ T++ DFLGKDSIRY N ++
Sbjct: 613 DYLALRVGGEKDADEADTVGCCSLRVEHIKFSEKKKNTITLDFLGKDSIRYFNT--LNDV 670
Query: 335 VFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
+ NL FC K+ S+ IF +++ LN+YL++LM GLSAKVFRT+NAS+TL
Sbjct: 671 AYDNLAKFCNRKKSSEGIFSKINTNKLNEYLRELMDGLSAKVFRTYNASITL 722
[218][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 159 bits (402), Expect = 1e-37
Identities = 85/147 (57%), Positives = 105/147 (71%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGK 292
+RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGK
Sbjct: 2 IRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIELHEQKDDKEFVVVFDFLGK 61
Query: 293 DSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
DSIRY N V V+K VF NLQLF NK P+D++F RL+ +N +L +LM GL+AKVFRTF
Sbjct: 62 DSIRYYNEVPVEKRVFKNLQLFMENKAPADDLFDRLNTQIMNKHLNELMDGLTAKVFRTF 121
Query: 473 NASVTLAECLQ--GDPGETVTDKVAFY 547
NAS TL + L + +T+++K+ Y
Sbjct: 122 NASYTLQQQLDELTNADDTLSEKILSY 148
[219][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 159 bits (401), Expect = 2e-37
Identities = 86/147 (58%), Positives = 103/147 (70%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGK 292
VRQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGK
Sbjct: 2 VRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIELHEQKDDKEYVVVFDFLGK 61
Query: 293 DSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
DSIRY N V V+K VF NLQLF NK P D++F RL+ +N +L +LM GL+AKVFRT+
Sbjct: 62 DSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTY 121
Query: 473 NASVTLAECLQ--GDPGETVTDKVAFY 547
NAS TL + L + +TV +K+ Y
Sbjct: 122 NASWTLQQQLDELTNDDDTVAEKILSY 148
[220][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 157 bits (398), Expect = 4e-37
Identities = 84/182 (46%), Positives = 112/182 (61%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S K SD K+EKAR L I IRK+Y++ ++ KE+ Q + A YL+DKLALR G
Sbjct: 170 ATSTVKAESDQKKYEKARSLHKYIEKIRKDYKRNMMSESKEMAQLAVATYLVDKLALRAG 229
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK ED ADTVG C+LR H+KF + FDFLGKDSI+Y ++D+ + LQ F +
Sbjct: 230 GEKDEDLADTVGVCTLRAGHIKFMDDNVIEFDFLGKDSIQYLQQHKIDEVAYKCLQRFVQ 289
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQG-DPGETVTDKVA 541
K P +IF + +N +L+ LMPGL+ KVFRT+NAS+TL L+ +T K A
Sbjct: 290 GKGPDVDIFDHVDPQKVNAHLQTLMPGLTIKVFRTYNASITLDRLLKDTKKNDTTLQKKA 349
Query: 542 FY 547
Y
Sbjct: 350 TY 351
[221][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 157 bits (397), Expect = 5e-37
Identities = 86/156 (55%), Positives = 106/156 (67%), Gaps = 4/156 (2%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG SD+ KFEKAR+LK I IR +Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 498 ANSDIKGQSDYKKFEKARELKKHIDRIRSDYKKGLKQELMAERQKATAVYLIDQFALRAG 557
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIRY + VEVD VF NL++F +
Sbjct: 558 NEKGEDEADTVGCCSLKYEHVTLKPPNTVIFDFLGKDSIRYYDEVEVDPQVFKNLKIFKK 617
Query: 365 -NKQPSDNIFHRLSVTSLNDY---LKQLMPGLSAKV 460
K+ D IF RL++ L LKQ+M L K+
Sbjct: 618 PPKKEGDEIFDRLTIKGLKYQQWRLKQMMLDLDPKL 653
[222][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 156 bits (394), Expect = 1e-36
Identities = 86/180 (47%), Positives = 117/180 (65%), Gaps = 18/180 (10%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S+FKG SD +K+ KA L I IRK Y+K +K EV+Q +TA ++ID+LALRVG
Sbjct: 234 AQSSFKGKSDRSKYSKAGLLCKNIEKIRKSYKKDLKSKDMEVKQLATATWVIDRLALRVG 293
Query: 185 NEK-AEDEADTVGCCSLRVEHLKFTP------PTTVSFDFLGKDSIRYENAVE------- 322
EK ++EADTVGCCSLRVEHL F P + +FLGKDS+ ++ ++
Sbjct: 294 GEKDTDEEADTVGCCSLRVEHLHFDPNGEGGDSKEIELEFLGKDSMLFKQTIDFGATLYN 353
Query: 323 ----VDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTL 490
+ V+ NL+ FC+ K+ S+ +FH ++ T LN++LKQ M GLSAKVFRT+NAS TL
Sbjct: 354 DSNGLGAQVYDNLKSFCKKKKSSEEVFHVINPTMLNNHLKQFMDGLSAKVFRTYNASKTL 413
[223][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 155 bits (391), Expect = 2e-36
Identities = 84/147 (57%), Positives = 102/147 (69%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGK 292
+RQR+ ALY IDKLALR GNEK ED+ADTVGCCSLRVEH+ K V FDFLGK
Sbjct: 2 IRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDDKEYVVVFDFLGK 61
Query: 293 DSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
DSIRY N V V+K VF NLQLF NK D++F RL+ +N +L +LM GL+AKVFRT+
Sbjct: 62 DSIRYYNEVPVEKRVFKNLQLFMENKSAGDDLFDRLNTQIMNKHLNELMEGLTAKVFRTY 121
Query: 473 NASVTLAECLQ--GDPGETVTDKVAFY 547
NAS TL + L + +TV +K+ Y
Sbjct: 122 NASWTLQQQLDELTNADDTVAEKILSY 148
[224][TOP]
>UniRef100_A6R590 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6R590_AJECN
Length = 651
Score = 155 bits (391), Expect = 2e-36
Identities = 80/137 (58%), Positives = 100/137 (72%), Gaps = 1/137 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG+SD+ KFEKAR+LK I IRK+Y+KG + RQ++TA+YLID+ ALR G
Sbjct: 502 ANSDIKGLSDYKKFEKARELKKHIDRIRKDYKKGLKHELMSERQKATAVYLIDQFALRAG 561
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
NEK EDEADTVGCCSL+ EH+ PP TV FDFLGKDSIR+ + VEVD VF NL++F +
Sbjct: 562 NEKGEDEADTVGCCSLKFEHVTLKPPNTVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKK 621
Query: 365 -NKQPSDNIFHRLSVTS 412
K+ D IF RL+ +S
Sbjct: 622 PPKREGDEIFDRLTTSS 638
[225][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 154 bits (388), Expect = 5e-36
Identities = 82/147 (55%), Positives = 102/147 (69%), Gaps = 7/147 (4%)
Frame = +2
Query: 128 VRQRSTALYLIDKLALRVGNEKAEDEADTVGCCSLRVEHL-----KFTPPTTVSFDFLGK 292
+RQR+ ALY ID+LALR GNEK ED+ADTVGCCSLRVEH+ K FDFLGK
Sbjct: 2 IRQRAVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHISLHEQKDGKEYVTVFDFLGK 61
Query: 293 DSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
DSIRY N V V+K VF NLQLF NK P D++F RL+ +N +L +LM GL+AKVFRT+
Sbjct: 62 DSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTQIMNKHLNELMDGLTAKVFRTY 121
Query: 473 NASVTLAECLQ--GDPGETVTDKVAFY 547
NAS TL + L + +T+ +K+ Y
Sbjct: 122 NASWTLQQQLDELTNADDTLAEKILSY 148
[226][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 153 bits (387), Expect = 7e-36
Identities = 82/182 (45%), Positives = 111/182 (60%), Gaps = 1/182 (0%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S K SD K+EKAR L I IR +Y++ ++ +E+ Q + YL+DKLALR G
Sbjct: 450 ATSTVKAESDQKKYEKARSLHKFIEKIRADYKRNMQSESREMAQLAVTTYLVDKLALRAG 509
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCR 364
EK ED ADTVG C+LR H+KF + FDFLGKDSI+Y ++D+ + LQ F +
Sbjct: 510 GEKDEDLADTVGVCTLRAGHIKFMEDNVIEFDFLGKDSIQYLQQHKIDEVAYKCLQRFVK 569
Query: 365 NKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL-QGDPGETVTDKVA 541
+K P +IF + + +N +L+ LMPGL+ KVFRT+NAS+TL L D T K A
Sbjct: 570 DKGPDVDIFDLIDPSKVNAHLQTLMPGLTIKVFRTYNASITLDSLLADTDTNLTTLQKKA 629
Query: 542 FY 547
Y
Sbjct: 630 KY 631
[227][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 149 bits (375), Expect = 2e-34
Identities = 85/147 (57%), Positives = 102/147 (69%), Gaps = 8/147 (5%)
Frame = +2
Query: 131 RQRSTALYLIDKLALRVGNEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGK 292
RQ + ALY IDKLALR GNEK E E ADTVGCCSLRVEH++ P V DFLGK
Sbjct: 4 RQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGK 63
Query: 293 DSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
DSIRY+N V V+K VF NLQ F +K P D++F L+ +SLN +L+ LM GL+AKVFRT+
Sbjct: 64 DSIRYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTY 123
Query: 473 NASVTLAECLQ--GDPGETVTDKVAFY 547
NASVTL E L+ ++VT KV Y
Sbjct: 124 NASVTLQEQLRVLTRAEDSVTCKVLAY 150
[228][TOP]
>UniRef100_P41511 DNA topoisomerase 1 n=1 Tax=Ustilago maydis RepID=TOP1_USTMA
Length = 1019
Score = 137 bits (346), Expect = 4e-31
Identities = 80/190 (42%), Positives = 112/190 (58%), Gaps = 23/190 (12%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FK SD KFEKAR+L + + IR++ K +K + RQ +T ++LID +LR G
Sbjct: 385 ATSNFKTNSDREKFEKARKLDTVVKQIRRDVNKNLKSKVRHERQIATIVWLIDNFSLRAG 444
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV-DKAVFFNLQLFC 361
NEK EDEA+T G CSLR EH + P T+ +FLGKDS+++E +++ + VF N+ +F
Sbjct: 445 NEKGEDEAETYGVCSLRCEHAQIKMPDTIHLEFLGKDSMKFEEDLKITNPDVFKNIAMFL 504
Query: 362 RN------------KQPSDNIF----------HRLSVTSLNDYLKQLMPGLSAKVFRTFN 475
++ K+PSD IF L S+N +L + M GLSAKVFRT+N
Sbjct: 505 KSNGMKDKSGNYVRKKPSDPIFCAPESGSGKMQPLQPNSVNQFLSKYMKGLSAKVFRTYN 564
Query: 476 ASVTLAECLQ 505
ASVT L+
Sbjct: 565 ASVTFQGLLE 574
[229][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 136 bits (342), Expect = 1e-30
Identities = 75/119 (63%), Positives = 88/119 (73%), Gaps = 6/119 (5%)
Frame = +2
Query: 167 LALRVGNEKAEDE-ADTVGCCSLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVD 328
LALR GNEK E E ADTVGCCSLRVEHL K V FDFLGKDSIRY NAV V+
Sbjct: 2 LALRAGNEKEEGETADTVGCCSLRVEHLTLHDSKDGKEFVVEFDFLGKDSIRYVNAVPVE 61
Query: 329 KAVFFNLQLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
K VF NL+LF NK+P+D++F RL+ + LN +L +LM GL+AKVFRT+NAS TL E L+
Sbjct: 62 KRVFRNLKLFMENKKPADDLFDRLNTSILNKHLNELMEGLTAKVFRTYNASKTLQEQLE 120
[230][TOP]
>UniRef100_UPI000179DDCD DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2)
(TOP1mt). n=1 Tax=Bos taurus RepID=UPI000179DDCD
Length = 620
Score = 134 bits (338), Expect = 3e-30
Identities = 83/175 (47%), Positives = 102/175 (58%), Gaps = 6/175 (3%)
Frame = +2
Query: 8 GSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGN 187
G KG D K+E A +LK + I +YR + RQR+ ALY I+KLAL+ GN
Sbjct: 223 GCKLKGERDWGKYEAAWRLKGAVGKICSQYRTAGTSPEMRTRQRAVALYFINKLALQTGN 282
Query: 188 EKAEDEADTVGCCSLRVEHLKFTP-----PTTVSFDFLGKDSIRYENAVEVDK-AVFFNL 349
E+ GCCSLRVEHL+ P P V FDFLGKDSIR N V V+K V+ NL
Sbjct: 283 --GEEGGGLGGCCSLRVEHLQLYPEASGSPDVVEFDFLGKDSIRSYNRVLVEKLQVYRNL 340
Query: 350 QLFCRNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDP 514
QLF NK P +F RL+ SLN +L+ GL+A+VFRT+N SV L LQ P
Sbjct: 341 QLFMDNKGPG-TLFDRLTTASLNRHLQDPTDGLTARVFRTYNTSVMLQGQLQALP 394
[231][TOP]
>UniRef100_A8PY85 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
7966 RepID=A8PY85_MALGO
Length = 877
Score = 124 bits (312), Expect = 3e-27
Identities = 72/177 (40%), Positives = 101/177 (57%), Gaps = 16/177 (9%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S FK SD KFEKAR+L +C+ +R + K +K + + +T ++LID +LR G
Sbjct: 343 ASSTFKTESDREKFEKARRLDTCVKQVRADVLKNLRSKDRLDQMIATIVWLIDNFSLRAG 402
Query: 185 NEKAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV-DKAVFFNLQLFC 361
NEK EDEA+T G CSLR H PP ++ FLGKDS+++E + + + V+ N+ F
Sbjct: 403 NEKGEDEAETYGVCSLRCGHATLIPPNQLNLSFLGKDSMKFEETLTITNPHVYKNITSFL 462
Query: 362 RN-----KQPSDNIFHR----------LSVTSLNDYLKQLMPGLSAKVFRTFNASVT 487
++ K P D IF L +N +L + M GLSAKVFRT+NAS T
Sbjct: 463 KSDGHQKKGPDDPIFAAPKARGDKMTPLPPDVVNQFLGRYMKGLSAKVFRTYNASAT 519
[232][TOP]
>UniRef100_C3ZV88 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3ZV88_BRAFL
Length = 299
Score = 124 bits (311), Expect = 5e-27
Identities = 66/116 (56%), Positives = 77/116 (66%), Gaps = 6/116 (5%)
Frame = +2
Query: 20 KGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNEKAE 199
+G D K+E AR+L C+ IR +YR+ W +K +RQR+ ALY IDKLALR GNEK
Sbjct: 2 QGEKDWMKYETARKLHKCVDRIRAQYREEWKSKEMRIRQRAVALYFIDKLALRAGNEKDS 61
Query: 200 DE-ADTVGCCSLRVEHLKF-----TPPTTVSFDFLGKDSIRYENAVEVDKAVFFNL 349
DE ADTVGCCSLRVEH+ V FDFLGKDSIRY N V V+K VF NL
Sbjct: 62 DEAADTVGCCSLRVEHINLHREHEGKEFVVEFDFLGKDSIRYHNFVAVEKKVFKNL 117
[233][TOP]
>UniRef100_A9A2H9 2-alkenal reductase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A2H9_NITMS
Length = 551
Score = 121 bits (304), Expect = 3e-26
Identities = 72/167 (43%), Positives = 101/167 (60%), Gaps = 3/167 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
S K D K+EKA +L+ I I+K K K + +TA YLI K A+RVG+E
Sbjct: 215 SDLKQGRDKEKYEKAVKLEKEIEKIKKAMVKDM--KDSKKNNVATACYLIYKTAMRVGDE 272
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV---DKAVFFNLQLFC 361
K EDEADTVG +LR EH+K T T+ FDFLGKDS+R++ ++V DK NL+
Sbjct: 273 KDEDEADTVGATTLRKEHIKIT-SDTIEFDFLGKDSVRWQETLKVVGDDKQFQENLKKLI 331
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECL 502
K+PS+ IFH ++ +N YL ++ G++AKVFRT+ A+ + L
Sbjct: 332 EKKKPSEEIFHDITSRDVNKYLSGIVKGVTAKVFRTYQATTVVKNYL 378
[234][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 120 bits (302), Expect = 5e-26
Identities = 58/102 (56%), Positives = 78/102 (76%)
Frame = +2
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNK 370
K +DEADTVGCC+L+VE++ PP ++ FDFLGKDSIRYE VEV+ V+ ++ F K
Sbjct: 1202 KDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRVGK 1261
Query: 371 QPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAE 496
SD++F +L + LN +LK+LMPGL+AKVFRT+NAS+TL E
Sbjct: 1262 SGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDE 1303
[235][TOP]
>UniRef100_Q0V9D3 Putative uncharacterized protein (Fragment) n=1 Tax=Xenopus
(Silurana) tropicalis RepID=Q0V9D3_XENTR
Length = 495
Score = 119 bits (298), Expect = 1e-25
Identities = 65/109 (59%), Positives = 75/109 (68%), Gaps = 6/109 (5%)
Frame = +2
Query: 5 AGSAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVG 184
A S KG D K+E AR+LK + +IRK YR+ + +K +VRQR+ ALY IDKLALR G
Sbjct: 347 ANSKLKGEKDWEKYEVARKLKHHVVTIRKTYRENFKSKEMKVRQRAVALYFIDKLALRAG 406
Query: 185 NEKAEDE-ADTVGCCSLRVEHLKFTPPT-----TVSFDFLGKDSIRYEN 313
NEK E E ADTVGCCSLRVEH+K P V FDFLGKDSIRY N
Sbjct: 407 NEKEEGETADTVGCCSLRVEHIKLYPELDGDKYVVEFDFLGKDSIRYYN 455
[236][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 116 bits (291), Expect = 9e-25
Identities = 57/118 (48%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 197 EDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQP 376
++EADTVGCC+L+V +++ PP + FDFLGKDSI+Y N VEV+ V+ + F K
Sbjct: 1 DNEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSK 60
Query: 377 SDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGE-TVTDKVAFY 547
+D++F L + LN +LK+L+PGL+AKVFRT+NAS+TL E L + + VT K+ Y
Sbjct: 61 TDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVY 118
[237][TOP]
>UniRef100_B3TAG0 Putative eukaryotic DNA topoisomerase I, catalytic core n=1
Tax=uncultured marine crenarchaeote HF4000_APKG8D22
RepID=B3TAG0_9ARCH
Length = 563
Score = 114 bits (285), Expect = 5e-24
Identities = 63/168 (37%), Positives = 101/168 (60%), Gaps = 3/168 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
+ K D AK++KA+ L I +++ + K + ++ ++ +TA YLI + ++RVG+E
Sbjct: 222 AGIKQEMDQAKYDKAKNLSKEIENVKAQIIKDMQSNEQKNKRIATACYLIYRTSMRVGDE 281
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV---DKAVFFNLQLFC 361
K DEADTVG +LR EH+K + + FDFLGKD +R+ + DK + NL+ F
Sbjct: 282 KDPDEADTVGATTLRKEHIKLS-ENAIEFDFLGKDGVRWRETIPAEGHDKQFYDNLKEFI 340
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
NK+ S IF ++ +N Y ++ GLSAKVFRT+ AS +++ L+
Sbjct: 341 ANKKESQEIFDGIASRHVNAYYSTIVKGLSAKVFRTYLASSVVSKNLR 388
[238][TOP]
>UniRef100_B3T4E9 Putative eukaryotic DNA topoisomerase I, catalytic core n=1
Tax=uncultured marine crenarchaeote HF4000_ANIW133O4
RepID=B3T4E9_9ARCH
Length = 563
Score = 114 bits (285), Expect = 5e-24
Identities = 63/168 (37%), Positives = 101/168 (60%), Gaps = 3/168 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
+ K D AK++KA+ L I +++ + K + ++ ++ +TA YLI + ++RVG+E
Sbjct: 222 AGIKQEMDQAKYDKAKNLSKEIENVKAQIIKDMQSNEQKNKRIATACYLIYRTSMRVGDE 281
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV---DKAVFFNLQLFC 361
K DEADTVG +LR EH+K + + FDFLGKD +R+ + DK + NL+ F
Sbjct: 282 KDPDEADTVGATTLRKEHIKLS-ENAIEFDFLGKDGVRWRETIPAEGHDKQFYDNLKEFI 340
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ 505
NK+ S IF ++ +N Y ++ GLSAKVFRT+ AS +++ L+
Sbjct: 341 ANKKESQEIFDGIASRHVNAYYSTIVKGLSAKVFRTYLASSVVSKNLR 388
[239][TOP]
>UniRef100_A0RU10 DNA topoisomerase IB n=1 Tax=Cenarchaeum symbiosum
RepID=A0RU10_CENSY
Length = 519
Score = 114 bits (284), Expect = 6e-24
Identities = 68/182 (37%), Positives = 107/182 (58%), Gaps = 3/182 (1%)
Frame = +2
Query: 11 SAFKGMSDHAKFEKARQLKSCIASIRKEYRKGWAAKGKEVRQRSTALYLIDKLALRVGNE 190
+ K D +K+EKA L I I + K +K ++ + +TA YLI + A+RVG+E
Sbjct: 212 AGLKQERDRSKYEKAVALSKKIGEIEAKIVKDMKSKDPKISKIATACYLIYRTAMRVGDE 271
Query: 191 KAEDEADTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEV---DKAVFFNLQLFC 361
K +DEADTVG +LR EH++ + + FDFLGKDSIR+ ++V D+ NLQ
Sbjct: 272 KDKDEADTVGATTLRKEHIRIS-DGVIEFDFLGKDSIRWNEKLKVTGDDEQFSRNLQGLV 330
Query: 362 RNKQPSDNIFHRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQGDPGETVTDKVA 541
++ +P D IF + + +N Y ++ G++AKVFRT+ AS ++E L+ + + K A
Sbjct: 331 KSIKPKDEIFKDIRSSDVNRYYSGIVKGVTAKVFRTYLASKKVSEYLR--KNDKIRSKSA 388
Query: 542 FY 547
F+
Sbjct: 389 FF 390
[240][TOP]
>UniRef100_Q7YZP3 Topoisomerase I subunit A (Fragment) n=1 Tax=Leishmania panamensis
RepID=Q7YZP3_9TRYP
Length = 88
Score = 105 bits (262), Expect = 2e-21
Identities = 53/88 (60%), Positives = 62/88 (70%)
Frame = +2
Query: 209 DTVGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNI 388
DTVGCCSLRVEH++ V FDFLGKDSIRY+N V V V+ LQ F R K P +I
Sbjct: 1 DTVGCCSLRVEHIQLMSDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTRRKSPGTDI 60
Query: 389 FHRLSVTSLNDYLKQLMPGLSAKVFRTF 472
F +L+ T LND+LK M GLSAKVFRT+
Sbjct: 61 FDQLNPTQLNDHLKSFMNGLSAKVFRTY 88
[241][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 104 bits (259), Expect = 5e-21
Identities = 59/114 (51%), Positives = 75/114 (65%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEERDDKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL E L + ++VT+K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASHTLQEQLDKLTNAEDSVTEKILSY 114
[242][TOP]
>UniRef100_Q9NGZ9 Topoisomerase I (Fragment) n=1 Tax=Leishmania donovani
RepID=Q9NGZ9_LEIDO
Length = 89
Score = 103 bits (258), Expect = 6e-21
Identities = 52/86 (60%), Positives = 61/86 (70%)
Frame = +2
Query: 215 VGCCSLRVEHLKFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIFH 394
VGCCSLRVEH++ P V FDFLGKDSIRY+N V V V+ LQ F R K P +IF
Sbjct: 4 VGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTRRKSPGMDIFD 63
Query: 395 RLSVTSLNDYLKQLMPGLSAKVFRTF 472
+L+ T LND+LK M GLSAKVFRT+
Sbjct: 64 QLNPTQLNDHLKSFMDGLSAKVFRTY 89
[243][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 103 bits (257), Expect = 8e-21
Identities = 59/114 (51%), Positives = 75/114 (65%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHL-----KFTPPTTVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH+ K V FDFLGKDSIRY N V V+K VF NLQLF NK P+D++F
Sbjct: 1 SLRVEHIELHERKDDRDHVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPADDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ + +N +L +LM GL+AKVFRT+NAS TL + L +TV +K+ Y
Sbjct: 61 DRLNTSIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTSADDTVAEKILSY 114
[244][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 103 bits (256), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[245][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 103 bits (256), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[246][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 102 bits (255), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[247][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 102 bits (255), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[248][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 102 bits (255), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[249][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 102 bits (255), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114
[250][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 102 bits (255), Expect = 1e-20
Identities = 58/114 (50%), Positives = 74/114 (64%), Gaps = 7/114 (6%)
Frame = +2
Query: 227 SLRVEHLKFTPPT-----TVSFDFLGKDSIRYENAVEVDKAVFFNLQLFCRNKQPSDNIF 391
SLRVEH++ V FDFLGKDSIRY N V V+K VF NLQLF NK P D++F
Sbjct: 1 SLRVEHIELHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKAPGDDLF 60
Query: 392 HRLSVTSLNDYLKQLMPGLSAKVFRTFNASVTLAECLQ--GDPGETVTDKVAFY 547
RL+ +N +L +LM GL+AKVFRT+NAS TL + L + +TV +K+ Y
Sbjct: 61 DRLNTQIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDELTNADDTVAEKILSY 114