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[1][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 194 bits (492), Expect = 5e-48
Identities = 89/186 (47%), Positives = 129/186 (69%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AAL+PI+D++ AVK YGI + T+MC++IL SG+ +H Y+LN+EK
Sbjct: 221 MTGFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKT-LHLYTLNMEK 279
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
+ +A++ LGL+ +++ R+LPWRP T R EDVRPIFWANRPKSY+ RT+ WD +P+
Sbjct: 280 TALAILMNLGLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPH 339
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G +++H G + E P+ S QD+ + FV F +G LK
Sbjct: 340 GRWGDSRNPSYGALNDHQFTRPRG----RGKKLQEEWAVPLKSVQDINERFVNFCEGKLK 395
Query: 543 RLPWVE 560
PW E
Sbjct: 396 SSPWSE 401
[2][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 191 bits (484), Expect = 4e-47
Identities = 89/186 (47%), Positives = 123/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT CKT+VP + AALEPI+D+D AV+ YGI + T+MC++IL + +H YSLNLEK
Sbjct: 233 MTTLCKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRT-LHLYSLNLEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
SV+ ++ LGL+ ++ R LPWRP T KR EDVRPIFWANRP+SY+ RT++WDDFP
Sbjct: 292 SVLGILQNLGLIDFSRVSRPLPWRPPTNSKRTKEDVRPIFWANRPRSYISRTTSWDDFPR 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD +PA+G S+H ++ +E P+ S +DV +F ++ +G+L
Sbjct: 352 GRWGDTANPAYGSFSDHQFTRK----KTRSKKLQKEWAVPLNSSEDVNAIFAKYCQGTLS 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 THPWSE 413
[3][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 188 bits (478), Expect = 2e-46
Identities = 86/186 (46%), Positives = 127/186 (68%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AAL+PI+D++ AVK+YGI + T+MC++IL +G+ +H Y+LN++K
Sbjct: 233 MTGFCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKT-LHLYTLNMDK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ R LPWRPAT R EDVRPIFWANRPKSYL+RT WD +P+
Sbjct: 292 SAIGILMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G +++H G + E P+ S +D+ + F F +G L
Sbjct: 352 GRWGDSRNPSYGALTDHQFTRPRG----RGKKLQEEWAVPLKSVEDISERFTNFCQGKLT 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[4][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 188 bits (477), Expect = 3e-46
Identities = 87/186 (46%), Positives = 123/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT CKT+VP + A LEPI+D+D AV+ YGI + T+MC++IL + +H YSLNLEK
Sbjct: 233 MTSLCKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRT-LHLYSLNLEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
SV+ ++ LGL+ ++ R LPWRP T KR EDVRPIFWANRP+SY+ RT++WD+FP
Sbjct: 292 SVLGILQNLGLIDFSKVTRPLPWRPPTNSKRTKEDVRPIFWANRPRSYISRTTSWDEFPR 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD +PA+G S+H + ++ +E P+ S +DV +F ++ +G+L
Sbjct: 352 GRWGDTGNPAYGSFSDHQFLRK----KTRSKKLQKEWAVPLNSCEDVNQIFAKYCQGTLS 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 THPWSE 413
[5][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 188 bits (477), Expect = 3e-46
Identities = 94/189 (49%), Positives = 125/189 (66%), Gaps = 3/189 (1%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT+VP + ALE I+D+D AVK YGI + MCR++L SG PG+H Y+LNLEK
Sbjct: 227 MTGFCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEK 286
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWR--PATLDKRRTEDVRPIFWANRPKSYLERTSAWDDF 356
S +A+++QLGLV ++ R LPWR PA R E VRP+FW+NRPK+Y++RT WD +
Sbjct: 287 SAVAILEQLGLVDTSRVQRPLPWRHVPAG-TARAVEQVRPVFWSNRPKAYVKRTQDWDSY 345
Query: 357 PNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPI-GSEQDVVDVFVRFFKG 533
P GRWG+ RSPA+G +S+H + T R +R +G S DV VFV++ KG
Sbjct: 346 PAGRWGNTRSPAYGALSDHQFMRRHS-TGEARREKARAAWGAAPASVDDVKQVFVKYIKG 404
Query: 534 SLKRLPWVE 560
+ LPW E
Sbjct: 405 EVSLLPWAE 413
[6][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 187 bits (475), Expect = 5e-46
Identities = 85/186 (45%), Positives = 127/186 (68%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AAL+PI+D++ AV++YGI + T+MC++IL +G+ +H Y+LN++K
Sbjct: 233 MTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKT-LHLYTLNMDK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ R LPWRPAT R EDVRPIFWANRPKSYL+RT WD +P+
Sbjct: 292 SAIGILMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G +++H G + E P+ S +D+ + F F +G L
Sbjct: 352 GRWGDSRNPSYGALTDHQFTRPRG----RGKKLQEEWAVPLKSVEDISERFTNFCQGKLT 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 187 bits (474), Expect = 6e-46
Identities = 86/186 (46%), Positives = 126/186 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AALEPI+D++ AVK YGI + T+MC++IL +G+ +H Y+LN+EK
Sbjct: 233 MTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKT-LHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWRP T R EDVRPIFWANRPKSY+ RT WD +P+
Sbjct: 292 SALGILMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G ++++ G + E P+ S +D+ + F+ F +G L
Sbjct: 352 GRWGDSRNPSYGALTDYQFTRPRG----RGKKLQEEWAVPVKSVEDINERFMNFCQGKLT 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 187 bits (474), Expect = 6e-46
Identities = 86/186 (46%), Positives = 126/186 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AALEPI+D++ AVK YGI + T+MC++IL +G+ +H Y+LN+EK
Sbjct: 233 MTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKT-LHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWRP T R EDVRPIFWANRPKSY+ RT WD +P+
Sbjct: 292 SALGILMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G ++++ G + E P+ S +D+ + F+ F +G L
Sbjct: 352 GRWGDSRNPSYGALTDYQFTRPRG----RGKKLQEEWAVPVKSVEDINERFMNFCQGKLT 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[9][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 186 bits (472), Expect = 1e-45
Identities = 87/186 (46%), Positives = 125/186 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D++ AV+ YGI + T+MC++IL G+ +H Y+LN+EK
Sbjct: 247 MTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKT-LHLYTLNMEK 305
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LGL+ +++ R+LPWRP T R EDVRPIFWANRPKSYL RT WD +P+
Sbjct: 306 SALAILMNLGLIEESKITRALPWRPPTNVFRAKEDVRPIFWANRPKSYLSRTIGWDQYPH 365
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+ +P++G +S++ + A + E P+ S +D+ + F + G LK
Sbjct: 366 GRWGDSHNPSYGALSDYQFM----RPRARGKKLFEEWASPLKSVEDIYEKFKVYCLGKLK 421
Query: 543 RLPWVE 560
PW E
Sbjct: 422 SSPWSE 427
[10][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 184 bits (467), Expect = 4e-45
Identities = 87/186 (46%), Positives = 124/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P V AALEPI+D++ AV+ YGI + T+MC++IL G+ +H Y+LN+EK
Sbjct: 244 MAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKT-LHLYTLNMEK 302
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LGL+ +++ R LPWRP T R EDVRPIFWANRPKSYL RT WD +P+
Sbjct: 303 SALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLTRTIGWDQYPH 362
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+R+P++G +S++ + A + E P+ S +D+ + F + G LK
Sbjct: 363 GRWGDSRNPSYGALSDYQFM----RPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLK 418
Query: 543 RLPWVE 560
PW E
Sbjct: 419 SSPWSE 424
[11][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 183 bits (465), Expect = 7e-45
Identities = 86/186 (46%), Positives = 122/186 (65%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P + AALEPI+D++ AV+ YGI + T+MC++IL G+ +H Y+LN+EK
Sbjct: 233 MAGFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKT-LHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ T+ R LPWRPAT R E+VRPIFWANRP+SY+ RT W+ FPN
Sbjct: 292 SALGILANLGLIDMTKIRRPLPWRPATNVLRTKENVRPIFWANRPRSYISRTIGWEQFPN 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD RSPA+G ++++ + + ++ E P+ S D+ + F F G LK
Sbjct: 352 GRWGDARSPAYGALNDYQFL----RRRSRSKKILEEWVVPLSSIVDIQEKFANFCVGKLK 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SNPWSE 413
[12][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 182 bits (463), Expect = 1e-44
Identities = 87/186 (46%), Positives = 123/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D++ AVK YGI + T+MC+++L G+ +H Y+LN+EK
Sbjct: 233 MTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVK-SLHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LG++ +++ RSLPWR R EDVRPIFWANRPKSY+ RT W+DFP
Sbjct: 292 SALAILMNLGMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQ 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+RS ++G +S+H A + +E P+ S +D+ + F G+LK
Sbjct: 352 GRWGDSRSASYGALSDHQF----SRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLK 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[13][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 181 bits (458), Expect = 4e-44
Identities = 93/196 (47%), Positives = 125/196 (63%), Gaps = 12/196 (6%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT KT+VP + LEPI+D+D VK+YG+++ +M +R+LD G+ G+HFY+LNLE+
Sbjct: 226 MTTLSKTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVE-GLHFYTLNLER 284
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
SV V+ L LV Q LPW + R E+VRPIFW NRP+SY+ RT +WD+FPN
Sbjct: 285 SVRKVLKGLQLVTPDQLSPFLPWAQSAAGNRLKEEVRPIFWQNRPRSYIARTGSWDEFPN 344
Query: 363 GRWGDNRSPAFGDISNHHLVG----SGGLTNADARAASR-------ELYGPI-GSEQDVV 506
GRWGD RSPAFGD+S++HL G GG N + + +YG SEQDV
Sbjct: 345 GRWGDYRSPAFGDLSDYHLGGVTPPPGGSANNNTTTTTTGDSVVVPNIYGDSPQSEQDVY 404
Query: 507 DVFVRFFKGSLKRLPW 554
+VF + G++KRLPW
Sbjct: 405 NVFASYCSGNIKRLPW 420
[14][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 179 bits (454), Expect = 1e-43
Identities = 85/190 (44%), Positives = 125/190 (65%), Gaps = 4/190 (2%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D++ AV+ YGI + T+MC++I+ G+ +H Y+LN+EK
Sbjct: 248 MTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKT-LHLYTLNMEK 306
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LGL+ +++ R LPWRP T R E VRPIFWANRPKSY+ RT W+ +P
Sbjct: 307 SALAILMNLGLIEESKISRPLPWRPPTNVFRVKEGVRPIFWANRPKSYISRTLGWEQYPQ 366
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYG----PIGSEQDVVDVFVRFFK 530
GRWGD+ +P++G +S+H + RA ++L+ P+ S +D+ + F +
Sbjct: 367 GRWGDSCNPSYGALSDHQFM--------RPRARDKKLHDEWVVPLSSAEDIFEKFKKHCL 418
Query: 531 GSLKRLPWVE 560
G LK PW E
Sbjct: 419 GKLKTSPWSE 428
[15][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 179 bits (453), Expect = 2e-43
Identities = 85/186 (45%), Positives = 123/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D+D AVK YGI + T+MC++IL G+ +H Y+LN+EK
Sbjct: 233 MTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKT-VHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LGL+ +++ R PWR T R EDVRPIFWANRP+SY+ RT WD +P+
Sbjct: 292 SALAILMNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANRPRSYISRTIGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRW D+ +P++G ++++ + A + E P+ S +DV + F++F G LK
Sbjct: 352 GRWSDSCNPSYGGLTDYQFM----RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLK 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[16][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 179 bits (453), Expect = 2e-43
Identities = 85/186 (45%), Positives = 123/186 (66%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D+D AVK YGI + T+MC++IL G+ +H Y+LN+EK
Sbjct: 233 MTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKT-VHLYTLNMEK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S +A++ LGL+ +++ R PWR T R EDVRPIFWANRP+SY+ RT WD +P+
Sbjct: 292 SALAILMNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANRPRSYISRTIGWDQYPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRW D+ +P++G ++++ + A + E P+ S +DV + F++F G LK
Sbjct: 352 GRWSDSCNPSYGGLTDYQFM----RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLK 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[17][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 177 bits (449), Expect = 5e-43
Identities = 86/186 (46%), Positives = 121/186 (65%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P + AALEPI+D+D AVK YGI AT+MC++IL G++ +H Y+LN++K
Sbjct: 43 MAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDK 101
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWR R EDVRPIFWANRPKSY+ RT W+DFP+
Sbjct: 102 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPH 161
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+ S A+ +S++ G + +E P+ S +DV + F G+LK
Sbjct: 162 GRWGDSHSAAYSTLSDYQFARPKGRD----KKLQQEWVVPLKSIEDVQEKFKELCIGNLK 217
Query: 543 RLPWVE 560
PW E
Sbjct: 218 SSPWSE 223
[18][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 177 bits (449), Expect = 5e-43
Identities = 86/186 (46%), Positives = 121/186 (65%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P + AALEPI+D+D AVK YGI AT+MC++IL G++ +H Y+LN++K
Sbjct: 233 MAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWR R EDVRPIFWANRPKSY+ RT W+DFP+
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRWGD+ S A+ +S++ G + +E P+ S +DV + F G+LK
Sbjct: 352 GRWGDSHSAAYSTLSDYQFARPKGRD----KKLQQEWVVPLKSIEDVQEKFKELCIGNLK 407
Query: 543 RLPWVE 560
PW E
Sbjct: 408 SSPWSE 413
[19][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 174 bits (442), Expect = 3e-42
Identities = 84/184 (45%), Positives = 123/184 (66%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++PP ALEP+++DDAAVKE G ++ DMCRR+L +G++ +HFY++NL ++ AV
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINH-LHFYTMNLAQATQAV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L+P +T R LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LEELKLIPSEETPLQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ + G+ + +L+G S +D+ +FVR+ +G L RLP
Sbjct: 348 TDSRSPAFGELDAY------GIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLP 401
Query: 552 WVEA 563
W ++
Sbjct: 402 WSDS 405
[20][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 174 bits (442), Expect = 3e-42
Identities = 84/184 (45%), Positives = 123/184 (66%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++PP ALEP+++DDAAVKE G ++ DMCRR+L +G++ +HFY++NL ++ AV
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINH-LHFYTMNLAQATQAV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L+P +T R LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LEELKLIPSEETPLQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ + G+ + +L+G S +D+ +FVR+ +G L RLP
Sbjct: 348 TDSRSPAFGELDAY------GIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLP 401
Query: 552 WVEA 563
W ++
Sbjct: 402 WSDS 405
[21][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 174 bits (442), Expect = 3e-42
Identities = 85/184 (46%), Positives = 122/184 (66%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++PP ALEP+++DDAAVKE G ++ DMCRR+L +G+ +HFY++NL ++ AV
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKH-LHFYTMNLAQATQAV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L+P +T R LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LEELKLIPSEETPLQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ + G+ + +L+G S +DV +FVR+ +G L RLP
Sbjct: 348 TDSRSPAFGELDAY------GIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLP 401
Query: 552 WVEA 563
W ++
Sbjct: 402 WSDS 405
[22][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 174 bits (440), Expect = 5e-42
Identities = 87/184 (47%), Positives = 124/184 (67%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
KT +PP ALEP+++DDAAVK+ G ++ DMCRR++ SG+ +HFY++NL +S V
Sbjct: 229 KTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASGIKH-LHFYTMNLAQSTQLV 287
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L P ++ R LPWRP+ RR EDVRPIFW NR SY+ RT+ WD+FPNGRW
Sbjct: 288 LEELELTPTAEAPIPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTAIWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ + VG G + + L+G S +D+ +VFVRF +G+L RLP
Sbjct: 348 TDSRSPAFGELELYG-VGLKGTNEQNIK-----LWGEPNSLRDLAEVFVRFLEGNLDRLP 401
Query: 552 WVEA 563
W ++
Sbjct: 402 WSDS 405
[23][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 173 bits (439), Expect = 7e-42
Identities = 82/187 (43%), Positives = 120/187 (64%), Gaps = 1/187 (0%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS-PGIHFYSLNLEK 182
T T++P ALEP++ DD V+E G K+ DMCR+ILDSGL G+HFY++NLEK
Sbjct: 186 TNLASTKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEK 245
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
++++L LVP+ ++I+ LPWR RR E +RPIFWANR KSY+ RT WD++PN
Sbjct: 246 GTRMLLEELNLVPRIETIKPLPWRQCLTPNRRNETIRPIFWANRTKSYISRTENWDEYPN 305
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GR+GD+RSPA+G+I + G + + +L+G + ++V +F +F KG L
Sbjct: 306 GRFGDSRSPAYGEIDGY------GTAIKQTKENALKLWGYPTTLEEVSVLFAKFCKGELD 359
Query: 543 RLPWVEA 563
LPW ++
Sbjct: 360 ALPWSDS 366
[24][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 173 bits (438), Expect = 9e-42
Identities = 83/181 (45%), Positives = 122/181 (67%), Gaps = 2/181 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
KT++PP ALEP+++DDAAV++ G ++ DMCRR++ +G++ +HFY++NL +S V
Sbjct: 229 KTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAGINH-LHFYTMNLAQSTQLV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+D+L L+P +T R+LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LDELNLMPSEETPLQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ ++ G+ + +L+G S +D+ +FV F +G L RLP
Sbjct: 348 TDSRSPAFGELDSY------GIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLP 401
Query: 552 W 554
W
Sbjct: 402 W 402
[25][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 172 bits (437), Expect = 1e-41
Identities = 85/187 (45%), Positives = 123/187 (65%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP ++ +EPI+D+DAA++ YGI++A ++CR +LDSGL PG+HFY+LN E + M V
Sbjct: 278 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 337
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 338 LKQLGMWTEDPR-RPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQGWDEFPNGRWGN 396
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 397 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 453
Query: 546 ----LPW 554
LPW
Sbjct: 454 RVTCLPW 460
[26][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 172 bits (437), Expect = 1e-41
Identities = 85/187 (45%), Positives = 123/187 (65%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP ++ +EPI+D+DAA++ YGI++A ++CR +LDSGL PG+HFY+LN E + M V
Sbjct: 313 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 373 LKQLGMWTEDPR-RPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQGWDEFPNGRWGN 431
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 432 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 488
Query: 546 ----LPW 554
LPW
Sbjct: 489 RVTCLPW 495
[27][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 171 bits (433), Expect = 4e-41
Identities = 86/187 (45%), Positives = 124/187 (66%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + + LEPI+D+DAA++ YGI++A +MCR +LDSG PG+HFY+LN E + M V
Sbjct: 277 KLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLGL + R LPW + KR+ EDVRPIFWA+RPKSY+ RT WDDFPNGRWG+
Sbjct: 337 LRQLGLWTEDPR-RPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGN 395
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++++++L L + ++ A +++G + SE+ V +VF + R
Sbjct: 396 SSSPAFGELNDYYLF---YLKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQ 452
Query: 546 ----LPW 554
LPW
Sbjct: 453 KVLCLPW 459
[28][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 171 bits (432), Expect = 5e-41
Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +CR +LDSGL PG+HFY+LN E + M V
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 373 LKQLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGN 431
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 432 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 488
Query: 546 ----LPW 554
LPW
Sbjct: 489 RVTCLPW 495
[29][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 171 bits (432), Expect = 5e-41
Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +CR +LDSGL PG+HFY+LN E + M V
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 373 LKQLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGN 431
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 432 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 488
Query: 546 ----LPW 554
LPW
Sbjct: 489 RVTCLPW 495
[30][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 171 bits (432), Expect = 5e-41
Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +CR +LDSGL PG+HFY+LN E + M V
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 373 LKQLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGN 431
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 432 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 488
Query: 546 ----LPW 554
LPW
Sbjct: 489 RVTCLPW 495
[31][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 171 bits (432), Expect = 5e-41
Identities = 83/184 (45%), Positives = 124/184 (67%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++PP ALEP+++DDAAVKE G ++ +MCR++L +GL+ +HFY++NL ++ +V
Sbjct: 229 KARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNH-LHFYTMNLAQATQSV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+D+L L+P +T R LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LDELKLIPSEETPLQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQIWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ + G+ + +L+G S +D+ +FVR+ +G L+RLP
Sbjct: 348 TDSRSPAFGELDAY------GIGLKGTNEQNIKLWGEPKSIRDISQIFVRYVEGKLERLP 401
Query: 552 WVEA 563
W ++
Sbjct: 402 WSDS 405
[32][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 170 bits (430), Expect = 8e-41
Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +CR +LDSGL PG+HFY+LN E + M V
Sbjct: 272 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEV 331
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 332 LKQLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGN 390
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G R
Sbjct: 391 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGY 447
Query: 546 ----LPW 554
LPW
Sbjct: 448 RVTCLPW 454
[33][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 169 bits (428), Expect = 1e-40
Identities = 80/181 (44%), Positives = 112/181 (61%), Gaps = 1/181 (0%)
Frame = +3
Query: 21 TQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS-PGIHFYSLNLEKSVMAV 197
T VP AL+P+RDDD V+E G ++ +MC++I+ +GL G+H Y++NLEK +
Sbjct: 247 TLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLEKGSRML 306
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+D LGL P + LPW P+ KRR E +RPIFWANR KSY+ RT WD+FPNGRWGD
Sbjct: 307 LDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFPNGRWGD 366
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWV 557
RSPA+GD+ + G+ + ++E++G DV +F +F G +K LPW
Sbjct: 367 ARSPAYGDVDAY------GVKLRYSNEEAKEMWGAPTCLDDVKTLFQQFCAGQVKALPWS 420
Query: 558 E 560
E
Sbjct: 421 E 421
[34][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 168 bits (426), Expect = 2e-40
Identities = 83/181 (45%), Positives = 119/181 (65%), Gaps = 2/181 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++PP ALEP+++DDAAVKE G + DMCRR+L +G++ +HFY++NL +S V
Sbjct: 229 KIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINH-LHFYTMNLAQSTQLV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L P +T + LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LEELNLTPSEETPLQKPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ ++ G+ + +L+G S +D+ +FV+F +G L RLP
Sbjct: 348 TDSRSPAFGELDSY------GIGLKGTNEQNIKLWGEPKSIRDLAHIFVKFMQGELARLP 401
Query: 552 W 554
W
Sbjct: 402 W 402
[35][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 168 bits (425), Expect = 3e-40
Identities = 95/200 (47%), Positives = 126/200 (63%), Gaps = 13/200 (6%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSLNL 176
MT +C VP + LEPI+DDD AVKE G +A +MCR+IL ++ G+HFY+LNL
Sbjct: 250 MTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNL 309
Query: 177 EKSVMAVVDQL------GLVPQ--TQSIRSLPWRPATLDKR-RTEDVRPIFWANRPKSYL 329
E+S ++ QL GLV + T+S R LPWRP+ + R + E VRPI WANRPKSY+
Sbjct: 310 ERSATRILMQLDGTVNSGLVDKIRTKSGRILPWRPSAMTGRSKMEQVRPINWANRPKSYV 369
Query: 330 ERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYG--PIGSEQDV 503
RT WD+FPNGRWGD+ SPAFG++SN S L + D + R + G P SE DV
Sbjct: 370 LRTEDWDEFPNGRWGDSTSPAFGELSNFSHYYSFSLGSEDDQ---RNMLGSNPTKSE-DV 425
Query: 504 VDVFVRFFKGSLKRLPWVEA 563
+VF + +G + +PW EA
Sbjct: 426 YEVFALYIEGKIPHIPWCEA 445
[36][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 167 bits (422), Expect = 7e-40
Identities = 83/187 (44%), Positives = 121/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A MC+ +L SGL PG+HFY+LN E + M V
Sbjct: 267 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEV 326
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT AWD+FPNGRWG+
Sbjct: 327 LKRLGMWNEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRWGN 385
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G +
Sbjct: 386 SSSPAFGELKDYYLF---CLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPNQNGY 442
Query: 546 ----LPW 554
LPW
Sbjct: 443 KVTCLPW 449
[37][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 167 bits (422), Expect = 7e-40
Identities = 83/187 (44%), Positives = 123/187 (65%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++P + + +EPI+D+DAA++ YGI++A MCR +LDSG PG+HFY+LN E + M V
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLGL + R LPW + KR+ EDVRPIFW++RPKSY+ RT WDDFPNGRWG+
Sbjct: 337 LRQLGLWIEDPR-RPLPWAVSAHPKRKVEDVRPIFWSSRPKSYIYRTQDWDDFPNGRWGN 395
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++++++L L + ++ A +++G + SE+ V +VF + R
Sbjct: 396 SSSPAFGELNDYYLF---YLKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQ 452
Query: 546 ----LPW 554
LPW
Sbjct: 453 KVLCLPW 459
[38][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 167 bits (422), Expect = 7e-40
Identities = 83/187 (44%), Positives = 123/187 (65%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++P + + +EPI+D+DAA++ YGI++A MCR +LDSG PG+HFY+LN E + M V
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLGL + R LPW + KR+ EDVRPIFW++RPKSY+ RT WDDFPNGRWG+
Sbjct: 337 LRQLGLWIEDPR-RPLPWAVSAHPKRKVEDVRPIFWSSRPKSYIYRTQDWDDFPNGRWGN 395
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++++++L L + ++ A +++G + SE+ V +VF + R
Sbjct: 396 SSSPAFGELNDYYLF---YLKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQ 452
Query: 546 ----LPW 554
LPW
Sbjct: 453 KVLCLPW 459
[39][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 167 bits (422), Expect = 7e-40
Identities = 84/188 (44%), Positives = 125/188 (66%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K +VPPS ALEP ++DDAAVK+ G K+ ++MCR+ILDSG+ +HFY++NL +S
Sbjct: 225 SNWVKCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRH-LHFYTMNLAQS 283
Query: 186 VMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+++L L+P +++ + LPWR + RR EDVRPIFW +R +SY+ RT WD+FP
Sbjct: 284 TKMVLEELDLIPSSETPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEFP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +D+ +FVRF + L
Sbjct: 344 NGRWTDSRSPAFGELDVY------GIGLKGTNEQNIKLWGEPKSIKDLSSIFVRFLEAKL 397
Query: 540 KRLPWVEA 563
RLPW E+
Sbjct: 398 DRLPWSES 405
[40][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 167 bits (422), Expect = 7e-40
Identities = 80/170 (47%), Positives = 114/170 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P + AALEPI+D+D AVK YGI AT+MC++IL G++ +H Y+LN++K
Sbjct: 233 MAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWR R EDVRPIFWANRPKSY+ RT W+DFP+
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDV 512
GRWGD+ S A+ +S++ G + +E P+ S +DV +V
Sbjct: 352 GRWGDSHSAAYSTLSDYQFARPKGRD----KKLQQEWVVPLKSIEDVQEV 397
[41][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 166 bits (421), Expect = 9e-40
Identities = 81/188 (43%), Positives = 126/188 (67%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
T + K ++P ALEP+++DDAAVK+ G + ++MCR++LD+G++ +HFY++NL +S
Sbjct: 225 TNWVKCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINH-LHFYTMNLAQS 283
Query: 186 VMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+++L L P T++ + LPWR + RR EDVRPIFW +R +SY+ RT +WD+FP
Sbjct: 284 TTMVLEELNLKPSTETPLQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +D+ D+F+RF +G L
Sbjct: 344 NGRWTDSRSPAFGELDVY------GIGLKGTNEQNIKLWGEPKSVKDLSDIFIRFLEGKL 397
Query: 540 KRLPWVEA 563
RLPW E+
Sbjct: 398 DRLPWSES 405
[42][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 166 bits (419), Expect = 1e-39
Identities = 82/181 (45%), Positives = 119/181 (65%), Gaps = 2/181 (1%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
+T K +P + +EPI+D+DAA+++YGI +ATDMCR +L+SG G+H Y+LNLE
Sbjct: 240 LTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLET 299
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRP-ATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
+ + ++ LGL Q + + LPW+ A ++R E VRPIFW +RPKSY+ RT WD+FP
Sbjct: 300 ATIQILKNLGLWCQDVA-KPLPWKTSANPERRENETVRPIFWCDRPKSYIHRTQGWDEFP 358
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGS 536
NGRWGD+ SPAFG++ ++HL L + A+ R L+G + SE DV VF F G+
Sbjct: 359 NGRWGDSASPAFGELKDYHLF---FLRSRTAKDKLRSLWGKELTSEADVWKVFKHFITGA 415
Query: 537 L 539
+
Sbjct: 416 V 416
[43][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 165 bits (418), Expect = 2e-39
Identities = 79/167 (47%), Positives = 112/167 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M GFCKT++P + AALEPI+D+D AVK YGI AT+MC++IL G++ +H Y+LN++K
Sbjct: 233 MAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGIT-SLHLYTLNVDK 291
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
S + ++ LGL+ +++ RSLPWR R EDVRPIFWANRPKSY+ RT W+DFP+
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPH 351
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDV 503
GRWGD+ S A+ +S++ G + +E P+ S +DV
Sbjct: 352 GRWGDSHSAAYSTLSDYQFARPKGRD----KKLQQEWVVPLKSIEDV 394
[44][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 165 bits (417), Expect = 3e-39
Identities = 88/193 (45%), Positives = 119/193 (61%), Gaps = 7/193 (3%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS---PGIHFYSLN 173
MT FC VP +V L IR DD AVK+ G K+ +MC +IL +GL G HFY+LN
Sbjct: 215 MTQFCGISVPSAVMDRLSNIRLDDEAVKQVGCKIVAEMCEQILSAGLEVDVDGFHFYTLN 274
Query: 174 LEKSVMAVVDQLGLVPQTQSIRS----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTS 341
LE+S ++ LG ++ RS LPW+P+ ++ R EDVRPI W+NRPKSY+ RT
Sbjct: 275 LERSTTRILTSLGAGSISEQARSTRRVLPWKPSAMENRSKEDVRPINWSNRPKSYVMRTD 334
Query: 342 AWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVR 521
WD+FPNGRWGD+ SPAFG++S+ S L + + R A L +E DV +VF R
Sbjct: 335 DWDEFPNGRWGDSTSPAFGELSDLSHFCSFTLGSDEDRRAM--LGHNPQAESDVYEVFAR 392
Query: 522 FFKGSLKRLPWVE 560
+ +GS+ +PW E
Sbjct: 393 YVEGSVPHIPWCE 405
[45][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 165 bits (417), Expect = 3e-39
Identities = 76/181 (41%), Positives = 113/181 (62%)
Frame = +3
Query: 12 FCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVM 191
+C+ Q+P LEP++DDD V+E G ++ DMC+++LDSG +HFY++NLEK+ +
Sbjct: 228 WCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATV 287
Query: 192 AVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
V+++L L Q ++ LPWRP+ R+ E VRPIFW NR +SY+ RT WD+FPNGRW
Sbjct: 288 MVLERLNLPAQDSAVAPLPWRPSLALGRQDETVRPIFWKNRKQSYVARTQDWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ + G+ + EL+G + D+ + V + G L LP
Sbjct: 348 GDSRSPAFGELETY------GVLLRQSPQKVLELWGEPKTVDDLKTLLVNYLNGKLASLP 401
Query: 552 W 554
W
Sbjct: 402 W 402
[46][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 164 bits (416), Expect = 3e-39
Identities = 83/187 (44%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI+ A +MC+ +L SG G+HFY+LN E + M V
Sbjct: 273 KLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEV 332
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLGL + R LPW + KR+ EDVRPIFWA+RPKSY+ RT WDDFPNGRWG+
Sbjct: 333 LRQLGLWAEDPR-RPLPWAISAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGN 391
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++++++L L + + A +++G + SE+ V +VF + G R
Sbjct: 392 SSSPAFGELTDYYLF---YLKSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGH 448
Query: 546 ----LPW 554
LPW
Sbjct: 449 KVMCLPW 455
[47][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 164 bits (416), Expect = 3e-39
Identities = 81/182 (44%), Positives = 119/182 (65%), Gaps = 5/182 (2%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++PP ALEPI+DDD V+E G ++ ++MC+++++SG +HFY++NLEK+ + +++
Sbjct: 232 KIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLEKATVMILE 291
Query: 204 QLGLVPQTQSI-----RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGR 368
+L LV +S LPWR + +R E +RPIFW NR SY+ RT+ WD+FPNGR
Sbjct: 292 KLNLVEAIKSHDLVGGTELPWRKSLHPERSKESIRPIFWQNRKYSYVSRTATWDEFPNGR 351
Query: 369 WGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRL 548
WGD+RSPAFGDI L S L + RA EL+G GS +++ D+ + + KG LK L
Sbjct: 352 WGDSRSPAFGDID---LCASELLRQSPKRA--YELWGTPGSLKELSDIVISYLKGDLKSL 406
Query: 549 PW 554
PW
Sbjct: 407 PW 408
[48][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 164 bits (415), Expect = 4e-39
Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C +L SGL PG+HFY+LN E + V
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 355
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 356 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 414
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VFV + G R
Sbjct: 415 SSSPAFGELKDYYLF---YLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 471
Query: 546 ----LPW 554
LPW
Sbjct: 472 KVTCLPW 478
[49][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 164 bits (415), Expect = 4e-39
Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C +L SGL PG+HFY+LN E + V
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 373
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 374 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 432
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VFV + G R
Sbjct: 433 SSSPAFGELKDYYLF---YLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 489
Query: 546 ----LPW 554
LPW
Sbjct: 490 KVTCLPW 496
[50][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 164 bits (415), Expect = 4e-39
Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI +A MCR +LDSGL G+HFY+LN E + + V
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 327 LKRLGMWKEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGN 385
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKG------- 533
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G
Sbjct: 386 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGH 442
Query: 534 SLKRLPW 554
+ LPW
Sbjct: 443 KVTCLPW 449
[51][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 164 bits (415), Expect = 4e-39
Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI +A MCR +LDSGL G+HFY+LN E + + V
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 327 LKRLGMWKEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGN 385
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKG------- 533
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G
Sbjct: 386 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGH 442
Query: 534 SLKRLPW 554
+ LPW
Sbjct: 443 KVTCLPW 449
[52][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 164 bits (415), Expect = 4e-39
Identities = 79/187 (42%), Positives = 123/187 (65%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP ALEP+++DDAAV+ G + DMC++IL SG+ +HFY++NL+++
Sbjct: 225 SNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
++D+LGL+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++F+RF GSL
Sbjct: 344 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[53][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 164 bits (415), Expect = 4e-39
Identities = 79/187 (42%), Positives = 123/187 (65%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP ALEP+++DDAAV+ G + DMC++IL SG+ +HFY++NL+++
Sbjct: 225 SNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
++D+LGL+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++F+RF GSL
Sbjct: 344 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[54][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 164 bits (415), Expect = 4e-39
Identities = 82/181 (45%), Positives = 117/181 (64%), Gaps = 2/181 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +P LEP+++DDAAVKE G + DMCRR+L +G++ +HFY++NL ++ V
Sbjct: 229 KIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAAGINH-LHFYTMNLAQATQLV 287
Query: 198 VDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+D+L L+P +T R LPWRP+ RR EDVRPIFW NR SY+ RT WD+FPNGRW
Sbjct: 288 LDELKLLPSEETPIQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
D+RSPAFG++ ++ G+ + +L+G S +D+ +FVR+ +G L RLP
Sbjct: 348 TDSRSPAFGELDSY------GIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLP 401
Query: 552 W 554
W
Sbjct: 402 W 402
[55][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 164 bits (415), Expect = 4e-39
Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C +L SGL PG+HFY+LN E + V
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 332
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 333 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 391
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VFV + G R
Sbjct: 392 SSSPAFGELKDYYLF---YLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 448
Query: 546 ----LPW 554
LPW
Sbjct: 449 KVTCLPW 455
[56][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 164 bits (414), Expect = 6e-39
Identities = 82/187 (43%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + A +EPI+D+DAA++ YGI++A MCR +L SG+ G+HFY+LN E + + V
Sbjct: 270 KLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEV 329
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 330 LKRLGIWNEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGN 388
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ N++L L + R +++G + SE+ V +VF + G +
Sbjct: 389 SSSPAFGELKNYYLF---CLKSKSPREELLKMWGQELTSEESVFEVFAYYLSGEPNQNGY 445
Query: 546 ----LPW 554
LPW
Sbjct: 446 KVTCLPW 452
[57][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 164 bits (414), Expect = 6e-39
Identities = 81/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI +A MCR +LDSGL G+HFY+LN E + + V
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R +PW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 327 LKRLGMWKEDPR-RPMPWAMSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGN 385
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKG------- 533
+ SPAFG++ +++L L + R +++G + SE+ V +VF + G
Sbjct: 386 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGQELNSEESVFEVFTYYISGEPNPNGH 442
Query: 534 SLKRLPW 554
+ LPW
Sbjct: 443 KVNCLPW 449
[58][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 164 bits (414), Expect = 6e-39
Identities = 80/184 (43%), Positives = 114/184 (61%), Gaps = 1/184 (0%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS-PGIHFYSLNLEK 182
T K VP S ALEPI++DD V+E G ++ DMCRRIL + G+HFY++NLEK
Sbjct: 226 TSLAKIVVPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEK 285
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
++++L LVP+ ++I+ LPWR + RR E +RPIFWANR KSY+ RT WD++PN
Sbjct: 286 GTKMLLEELNLVPRIETIKPLPWRQSLTPNRRQESIRPIFWANRTKSYISRTENWDEYPN 345
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GR+GD+RSPA+G++ + G+ + +L+G S D+ +F RF L
Sbjct: 346 GRFGDSRSPAYGELDGY------GVWIKQTVKDALKLWGHPTSFADIASLFSRFCTKKLS 399
Query: 543 RLPW 554
LPW
Sbjct: 400 ALPW 403
[59][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 163 bits (413), Expect = 7e-39
Identities = 81/187 (43%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 355
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 356 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 414
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V +VFV + G R
Sbjct: 415 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 471
Query: 546 ----LPW 554
LPW
Sbjct: 472 KVTCLPW 478
[60][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 163 bits (413), Expect = 7e-39
Identities = 81/187 (43%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 373
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 374 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 432
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V +VFV + G R
Sbjct: 433 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 489
Query: 546 ----LPW 554
LPW
Sbjct: 490 KVTCLPW 496
[61][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 163 bits (413), Expect = 7e-39
Identities = 81/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI+ A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 398 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 457
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 458 LKRLGMWIEDPR-RPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 516
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF R+ G +
Sbjct: 517 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGY 573
Query: 546 ----LPW 554
LPW
Sbjct: 574 KVTCLPW 580
[62][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 163 bits (413), Expect = 7e-39
Identities = 81/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI+ A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 314 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 373
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 374 LKRLGMWIEDPR-RPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 432
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + SE+ V +VF R+ G +
Sbjct: 433 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGY 489
Query: 546 ----LPW 554
LPW
Sbjct: 490 KVTCLPW 496
[63][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 163 bits (413), Expect = 7e-39
Identities = 84/188 (44%), Positives = 118/188 (62%), Gaps = 9/188 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
+ +VP S+ L+ I+D+D A++ YG++ A +MCR +LDSGL PG+HFY+LN E + +
Sbjct: 216 RLEVPKSIMDDLQTIKDNDVAIRNYGVQKAINMCRELLDSGLVPGLHFYTLNREVATREI 275
Query: 198 VDQLGL-VPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWG 374
+ LGL + R LPWR + KR TEDVRPIFWA+RPKSYL RTS WD+FPNGRWG
Sbjct: 276 LTALGLWCMDPAASRPLPWRASANQKRFTEDVRPIFWASRPKSYLYRTSDWDEFPNGRWG 335
Query: 375 DNRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKG------ 533
++ +PAF D S+HHL L + + +++G + QDV +VF + G
Sbjct: 336 NSSAPAFRDFSDHHLF---YLRSKAKKEQMLKMWGQQLNDVQDVFEVFKCYISGEKNENG 392
Query: 534 -SLKRLPW 554
+ LPW
Sbjct: 393 VKVTSLPW 400
[64][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 163 bits (413), Expect = 7e-39
Identities = 81/187 (43%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 332
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 333 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 391
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V +VFV + G R
Sbjct: 392 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGH 448
Query: 546 ----LPW 554
LPW
Sbjct: 449 KVTCLPW 455
[65][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 163 bits (412), Expect = 1e-38
Identities = 81/178 (45%), Positives = 112/178 (62%), Gaps = 2/178 (1%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS--PGIHFYSLNLEKSVMAVV 200
VP AL P+R DD V++ G K+ DMC+ ILD+ + G+H Y+LNLEK ++
Sbjct: 236 VPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLL 295
Query: 201 DQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
+LG + + I LPWRP+ RR E +RPIFWANR +SYL RT+ WD+FPNGRWGD+
Sbjct: 296 RELGFEGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDS 355
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
RSPA+GD+ + + S G+T DA L+G + D+ +F RF +G L +LPW
Sbjct: 356 RSPAYGDLDGYPV--SIGITAPDA----YNLWGHPTTSSDLHALFARFCRGDLAKLPW 407
[66][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 162 bits (411), Expect = 1e-38
Identities = 82/188 (43%), Positives = 124/188 (65%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K +VP S ALEP+++DDAAVK+ G K+ +MC++ILDSG+ +HFY++NL ++
Sbjct: 225 SNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRH-LHFYTMNLAQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+++L L+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD+FP
Sbjct: 284 TKMVLEELKLIPSYETPLQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +D+ +F+RF +G L
Sbjct: 344 NGRWTDSRSPAFGELDVY------GIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGL 397
Query: 540 KRLPWVEA 563
RLPW E+
Sbjct: 398 DRLPWSES 405
[67][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 162 bits (411), Expect = 1e-38
Identities = 82/188 (43%), Positives = 124/188 (65%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K +VP S ALEP+++DDAAVK+ G K+ +MC++ILDSG+ +HFY++NL ++
Sbjct: 225 SNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRH-LHFYTMNLAQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+++L L+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD+FP
Sbjct: 284 TKMVLEELKLIPSYETPLQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +D+ +F+RF +G L
Sbjct: 344 NGRWTDSRSPAFGELDVY------GIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGL 397
Query: 540 KRLPWVEA 563
RLPW E+
Sbjct: 398 DRLPWSES 405
[68][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 162 bits (411), Expect = 1e-38
Identities = 78/187 (41%), Positives = 122/187 (65%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K Q+PP ALEP+++DDAAV+ G + +MC+++L SG+ +HFY++NL+++
Sbjct: 225 SNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+D+LGL+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++F+RF G L
Sbjct: 344 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIQLWGKPKSLKELSEIFIRFLNGKL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[69][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 162 bits (411), Expect = 1e-38
Identities = 78/187 (41%), Positives = 122/187 (65%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K Q+PP ALEP+++DDAAV+ G + +MC+++L SG+ +HFY++NL+++
Sbjct: 225 SNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+D+LGL+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++F+RF G L
Sbjct: 344 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIQLWGKPKSLKELSEIFIRFLNGKL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[70][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 162 bits (410), Expect = 2e-38
Identities = 80/187 (42%), Positives = 118/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YG+++A MCR +LDSG+ G+HFY+LN E + V
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LGL + R LPW + KRR EDVRPIFWA+RPKSY+ RT WDDFPNGRWG+
Sbjct: 335 LKRLGLWNEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGN 393
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + R +++G + E+ V +VF + G +
Sbjct: 394 SSSPAFGELKDYYLF---YLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGY 450
Query: 546 ----LPW 554
+PW
Sbjct: 451 KVTCMPW 457
[71][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 162 bits (410), Expect = 2e-38
Identities = 81/187 (43%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI++A +C+ +L SGL PG+HFY+LN E + V
Sbjct: 303 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 362
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 363 LKRLGMWTEDPR-RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 421
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE V +VFV + G R
Sbjct: 422 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEASVFEVFVLYLSGEPNRNGH 478
Query: 546 ----LPW 554
LPW
Sbjct: 479 KVTCLPW 485
[72][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 162 bits (409), Expect = 2e-38
Identities = 81/180 (45%), Positives = 117/180 (65%), Gaps = 1/180 (0%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + LEPI++DD A++EYG+K+A MCR +L S PGIH Y+LN E + +
Sbjct: 250 KLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTLNREVATTEL 309
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ QLGL QS R LPW+P+ KR EDVRPIFW++RPKSY+ RTS WD+FPNGRWG+
Sbjct: 310 LQQLGLWRPYQSHRLLPWKPSANLKRLQEDVRPIFWSSRPKSYIHRTSNWDEFPNGRWGN 369
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKRLPW 554
+ +P+F ++S+HHL L + ++ +++G + +DV VF + G K+ W
Sbjct: 370 SSAPSFAELSDHHLF---YLKSKESEEERLKMWGEKLDCIEDVYHVFQCYLSG--KKNKW 424
[73][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 160 bits (406), Expect = 5e-38
Identities = 77/187 (41%), Positives = 121/187 (64%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K Q+PP ALEP+++DDAAV+ G + +MC+++L SG+ +HFY++NL+++
Sbjct: 225 SNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+D+LGL+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++F+ F G L
Sbjct: 344 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIQLWGKPKSLKELSEIFIHFLNGKL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[74][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 160 bits (405), Expect = 6e-38
Identities = 80/187 (42%), Positives = 118/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI+ A +C+ +L SGL PG+HFY+LN E + + V
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LGL + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 332 LKRLGLWIEDPR-RPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 390
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V VF + G +
Sbjct: 391 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQNGY 447
Query: 546 ----LPW 554
LPW
Sbjct: 448 KVTCLPW 454
[75][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 160 bits (404), Expect = 8e-38
Identities = 79/187 (42%), Positives = 117/187 (62%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YG+++A MCR +LDSGL G+HFY+LN E + V
Sbjct: 131 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 190
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WDDFPNGRWG+
Sbjct: 191 LKRLGIWNEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGN 249
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L + R +++G + E+ V +VF + G +
Sbjct: 250 SSSPAFGELKDYYLFYL--KSKPSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGH 307
Query: 546 ----LPW 554
+PW
Sbjct: 308 RVTCMPW 314
[76][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 160 bits (404), Expect = 8e-38
Identities = 79/187 (42%), Positives = 118/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YG+++A MCR +LDSGL G+HFY+LN E + V
Sbjct: 263 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 322
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA+RPKSY+ RT WDDFPNGRWG+
Sbjct: 323 LKRLGIWNEDPR-RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGN 381
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L ++ R +++G + E+ V +VF + G +
Sbjct: 382 SSSPAFGELKDYYLFYL--KSSLPPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGH 439
Query: 546 ----LPW 554
+PW
Sbjct: 440 RVTCMPW 446
[77][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 159 bits (403), Expect = 1e-37
Identities = 78/183 (42%), Positives = 120/183 (65%), Gaps = 2/183 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
+ +P ALEPI++DD V+E G + DMCRR++++G++ +HFY++NL ++ V
Sbjct: 229 RCNIPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEAGITH-LHFYTMNLAQATRMV 287
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L+P S + LPWRP+ RR E+VRPIFW NR +SY+ RT WD+FPNGRW
Sbjct: 288 LEELDLLPDPGSPLEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ ++ G+ + +L+G S +D+ D+FVR+ +G L+ LP
Sbjct: 348 GDSRSPAFGELDSY------GIGLKGTNEQNIKLWGTPLSIKDLSDLFVRYMEGKLESLP 401
Query: 552 WVE 560
W E
Sbjct: 402 WSE 404
[78][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 159 bits (402), Expect = 1e-37
Identities = 76/174 (43%), Positives = 109/174 (62%), Gaps = 2/174 (1%)
Frame = +3
Query: 48 ALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSLNLEKSVMAVVDQLGLVP 221
AL+P+++DD V+ G ++ DMC++IL+ G+H Y++NLE+ +++ LGL P
Sbjct: 164 ALDPVKEDDEQVRIVGTRLVGDMCKKILEHPDLDIHGVHIYTMNLERGSRMLLEYLGLTP 223
Query: 222 QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGD 401
Q + LPWRP+ KRR E++RPIFWANR KSY++RT AWD+FPNGRWGD RSPA+GD
Sbjct: 224 SVQQLHPLPWRPSLTPKRREENIRPIFWANRAKSYIDRTDAWDEFPNGRWGDARSPAYGD 283
Query: 402 ISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
G + + +L+G + QD+ +F RF G L LPW +A
Sbjct: 284 ADVF------GPYLRQTKEEALDLWGSPTTIQDLQSLFARFCTGELACLPWSDA 331
[79][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 159 bits (401), Expect = 2e-37
Identities = 75/188 (39%), Positives = 122/188 (64%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP LEP++ DDA V+E G K+ +MCR++L SG +HFY++NL ++
Sbjct: 225 SNWTKIRIPPDWLDKLEPVKADDAKVREIGTKLVAEMCRKLLASGQIHHLHFYTMNLAQA 284
Query: 186 VMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
++++L L+P ++ + LPWR + +RR+EDVRPIFW NR SY+ RT+ WD++P
Sbjct: 285 TRLILEELRLLPSEEAPLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYP 344
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D RSPAFG+++ + G+ + +L+G S +D+ D+FVR+ G +
Sbjct: 345 NGRWTDARSPAFGELNAY------GVRLKGTNEQNIKLWGAPKSIKDLSDIFVRYLNGKV 398
Query: 540 KRLPWVEA 563
+RLPW ++
Sbjct: 399 ERLPWSDS 406
[80][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 159 bits (401), Expect = 2e-37
Identities = 75/188 (39%), Positives = 122/188 (64%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP LEP++ DDA V+E G K+ +MCR++L SG +HFY++NL ++
Sbjct: 225 SNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLAQA 284
Query: 186 VMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
++++L L+P ++ + LPWR + +RR+EDVRPIFW NR SY+ RT+ WD++P
Sbjct: 285 TRLILEELRLLPSEEAPLQKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYP 344
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D RSPAFG+++ + G+ + +L+G S +D+ D+F+R+ G L
Sbjct: 345 NGRWTDARSPAFGELNAY------GVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKL 398
Query: 540 KRLPWVEA 563
+RLPW ++
Sbjct: 399 ERLPWSDS 406
[81][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 159 bits (401), Expect = 2e-37
Identities = 80/187 (42%), Positives = 117/187 (62%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YGI+ A +C+ +L SGL PG+HFY+LN E + + V
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LGL + R LPW + KRR EDVRPIFWA+RPKSY+ RT WD+FPNGRWG+
Sbjct: 332 LKRLGLWIEDPR-RPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN 390
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V VF G +
Sbjct: 391 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFQVFAHHLSGEPNQNGY 447
Query: 546 ----LPW 554
LPW
Sbjct: 448 KVTCLPW 454
[82][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 157 bits (398), Expect = 4e-37
Identities = 81/190 (42%), Positives = 117/190 (61%), Gaps = 6/190 (3%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGL-----SPGIHFYS 167
MT FCKT+VP ++ LE ++ DD VK+ G+++ MC +I+ G+ S G+HFY+
Sbjct: 198 MTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYT 257
Query: 168 LNLEKSVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW 347
LNLE SV ++++L +V + R LPWRP+ R+ E+VRPIFW NR KS+++RTS+W
Sbjct: 258 LNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRPIFWRNRQKSFIQRTSSW 317
Query: 348 DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRF 524
D+FPNGR G+ S A+GD + S T A R ++G + + V VF F
Sbjct: 318 DEFPNGRLGNQASAAYGDFELNFRSYSKE-TQEKVAADRRRMWGDHVPNGDHVRRVFTDF 376
Query: 525 FKGSLKRLPW 554
KG +KRLPW
Sbjct: 377 IKGEVKRLPW 386
[83][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 157 bits (398), Expect = 4e-37
Identities = 76/182 (41%), Positives = 118/182 (64%), Gaps = 2/182 (1%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++PP A+LE +++DD+AV+ G + +MCRRI+ +G+ +HFY++NL ++ V++
Sbjct: 231 KIPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHH-LHFYTMNLAQATRMVLE 289
Query: 204 QLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+L L P TQ +LPWR + RR EDVRPIFW NR KSY+ RT WD+FPNGRWGD
Sbjct: 290 ELNLTPSTQRPLKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGD 349
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWV 557
+RSPAFG++ + G+ + + +L+G S +D+ ++FV + + ++ LPW
Sbjct: 350 SRSPAFGELDAY------GIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENGIESLPWS 403
Query: 558 EA 563
EA
Sbjct: 404 EA 405
[84][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 157 bits (397), Expect = 5e-37
Identities = 78/187 (41%), Positives = 116/187 (62%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+D A++ YGI A +C+++L SGL PG+HFY+LN E + V
Sbjct: 272 KLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEV 331
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ +LG+ + R LPW + KRR EDVRPIFWA RPKSY+ RT WD+FPNGRWG+
Sbjct: 332 LKRLGMWVEDPR-RPLPWALSAHPKRREEDVRPIFWATRPKSYIYRTQEWDEFPNGRWGN 390
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ +++L L + + +++G + SE+ V +VF + G +
Sbjct: 391 SSSPAFGELKDYYLF---YLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSGEPNQNGY 447
Query: 546 ----LPW 554
LPW
Sbjct: 448 KVTCLPW 454
[85][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 157 bits (397), Expect = 5e-37
Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P A LEP+++DD AV+E G + +MCR+I+D+G+ +HFY++NL ++ V++
Sbjct: 231 KIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRH-LHFYTMNLAQATRMVLE 289
Query: 204 QLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+L +P R+LPW+ + RR EDVRPIFW NR KSY+ RT WD+FPNGRWGD
Sbjct: 290 ELDWLPSPNRPLKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQDWDEFPNGRWGD 349
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWV 557
+RSPAFG++ + + GLT ++ +R+ +G + +D+ ++FVR+ L+ LPW
Sbjct: 350 SRSPAFGELDAYGI----GLTGSN--ELNRKKWGEPQTVKDIANLFVRYLNQELEYLPWS 403
Query: 558 EA 563
EA
Sbjct: 404 EA 405
[86][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 157 bits (396), Expect = 7e-37
Identities = 76/187 (40%), Positives = 120/187 (64%), Gaps = 8/187 (4%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K VP + +E I+D+D A++++GI AT++C+++L S PGIH Y+LN E++V+ +
Sbjct: 256 KLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKL 315
Query: 198 VDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+ ++GL + +SLPWRP+ KR +EDVRPIFWA+RPKSY+ RT WD++PNGRWG
Sbjct: 316 LKRVGLWHEESIYKSLPWRPSANGKRISEDVRPIFWASRPKSYVHRTMMWDEYPNGRWGS 375
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKGSLKR--- 545
+ SPAFG++ ++H+ L N + +++G + S +DV ++F F G +
Sbjct: 376 SASPAFGELKDYHIF---YLKNTSKKDELLKMWGEKLESVEDVYEIFTCFVSGERNKYGY 432
Query: 546 ----LPW 554
LPW
Sbjct: 433 KVDALPW 439
[87][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 156 bits (395), Expect = 9e-37
Identities = 76/183 (41%), Positives = 116/183 (63%), Gaps = 5/183 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P AL+PI+DDD V+E G ++ ++MC+++L+SG +HFY++NLEK+ + ++++
Sbjct: 232 IPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMILEK 291
Query: 207 LGLVPQTQS-----IRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L L+ +S + LPWR + +R E +RPIFW NR SY+ RT+ WD+FPNGRW
Sbjct: 292 LNLIEAVKSNEIVGVTELPWRKSLNPERSKESIRPIFWQNRKYSYVTRTATWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L S L + RA +EL+G + D+ + + + KG L LP
Sbjct: 352 GDSRSPAFGDID---LCASELLRQSPKRA--QELWGLPQTISDITGLVISYLKGQLNSLP 406
Query: 552 WVE 560
W +
Sbjct: 407 WFD 409
[88][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 156 bits (395), Expect = 9e-37
Identities = 79/192 (41%), Positives = 119/192 (61%), Gaps = 7/192 (3%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ +C+ VP + A L+P++DDD AV+E G ++ MC+++LDSG +H Y++NLEK+
Sbjct: 228 SSWCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKA 287
Query: 186 VMAVVDQLGLVPQTQSI-----RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW- 347
+ V+D+LGL+ + + I +PWR + +RR E VRPIFW RP SY+ RTS W
Sbjct: 288 CIMVLDRLGLLSEDEDIFRDEVVPMPWRKSLHPQRRNESVRPIFWQKRPYSYVARTSQWT 347
Query: 348 -DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRF 524
D+FPNGR+GD+ SPAFGD+ L+GS + + RA EL+ D+ + + +
Sbjct: 348 ADEFPNGRFGDSSSPAFGDLD---LLGSTSIRQSPQRAL--ELWSTPTKFSDIAALVIDY 402
Query: 525 FKGSLKRLPWVE 560
G LK LPW +
Sbjct: 403 LHGKLKCLPWCD 414
[89][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 156 bits (395), Expect = 9e-37
Identities = 79/187 (42%), Positives = 122/187 (65%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP ALEP+++DDAAV+ G + +MCR+IL +G+ +HFY++NL+++
Sbjct: 225 SNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYH-LHFYTMNLQQA 283
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+ +L L+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 284 TKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + VG G + + L+G S +++ ++FVRF G+L
Sbjct: 344 NGRWTDSRSPAFGELDTYG-VGLKGTNEQNIK-----LWGEPKSLKELSEIFVRFLNGNL 397
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 398 DRLPWSE 404
[90][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 156 bits (394), Expect = 1e-36
Identities = 77/187 (41%), Positives = 121/187 (64%), Gaps = 2/187 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K ++PP ALEP+++DDAAV+ G + +MCR+IL +G+ +HFY++NL+++
Sbjct: 116 SNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYH-LHFYTMNLQQA 174
Query: 186 VMAVVDQLGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+ +L L+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++P
Sbjct: 175 TKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYP 234
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + G+ + +L+G S +++ ++FVRF G+L
Sbjct: 235 NGRWTDSRSPAFGELDTY------GIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNL 288
Query: 540 KRLPWVE 560
RLPW E
Sbjct: 289 DRLPWSE 295
[91][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 156 bits (394), Expect = 1e-36
Identities = 78/188 (41%), Positives = 119/188 (63%), Gaps = 2/188 (1%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ + K +VP ALEP+++DD+AV++ G + +MCR+++ +G+ +HFY++NL ++
Sbjct: 225 SNWTKVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAGIKH-LHFYTMNLAQA 283
Query: 186 VMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
V+ +L L P S R LPWRP+ RR+EDVRP+FW NR SY+ RT WD++P
Sbjct: 284 TQLVLKELELTPSEDSPIQRPLPWRPSLGLGRRSEDVRPVFWRNRNSSYVARTQTWDEYP 343
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGRW D+RSPAFG++ + VG G + + L+G S +D+ D+FV F G L
Sbjct: 344 NGRWTDSRSPAFGELDAYG-VGLKGTNEQNIK-----LWGEPKSIKDISDIFVNFLTGKL 397
Query: 540 KRLPWVEA 563
RLPW ++
Sbjct: 398 DRLPWSDS 405
[92][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 155 bits (393), Expect = 2e-36
Identities = 75/183 (40%), Positives = 119/183 (65%), Gaps = 2/183 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
+ +P ALEP+++DD V+E G + DMCR+++ +G++ +HFY++NL ++ V
Sbjct: 229 RCNIPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAAGITH-LHFYTMNLAQATRMV 287
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L L+P ++ + LPWRP+ RR E+VRPIFW NR +SY+ RT WD+FPNGRW
Sbjct: 288 LEELDLLPDVEAPLEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ ++ +G G + + L+G +D+ D+FVR+ +G L LP
Sbjct: 348 GDSRSPAFGELDSYG-IGLKGTNEQNVK-----LWGSPMCIRDLSDLFVRYMEGKLDSLP 401
Query: 552 WVE 560
W E
Sbjct: 402 WSE 404
[93][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 154 bits (390), Expect = 3e-36
Identities = 79/186 (42%), Positives = 114/186 (61%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P V AALEPI+D+D AVK YGI + T+MC++IL + GI + L ++
Sbjct: 233 MTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKIL----AHGIKTFGLTMDL 288
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
LGL+ +++ R PWR T R EDVRPIFWANRP+SY+ RT WD +P+
Sbjct: 289 PWQ----NLGLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANRPRSYISRTIGWDQYPH 344
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GRW D+ +P++G ++++ + A + E P+ S +DV + F++F G LK
Sbjct: 345 GRWSDSCNPSYGGLTDYQFM----RPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLK 400
Query: 543 RLPWVE 560
PW E
Sbjct: 401 SSPWSE 406
[94][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 154 bits (390), Expect = 3e-36
Identities = 76/180 (42%), Positives = 112/180 (62%), Gaps = 4/180 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P AL PI++DD A++E G ++ ++MC++++DSG +HFY++NLE+S + ++++
Sbjct: 235 IPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEK 294
Query: 207 LGLVPQTQS----IRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWG 374
L LV + + LPWR + R E +RPIFW NR SY+ RTS WD+FPNGRWG
Sbjct: 295 LNLVESIKDNDAVVEILPWRKSLNPSRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWG 354
Query: 375 DNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
D+RSPAFGDI L S L + RA EL+G + D+ D+ V + +K LPW
Sbjct: 355 DSRSPAFGDID---LSASELLRQSPKRA--YELWGCPQTLNDLSDIIVSYLNNEVKALPW 409
[95][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 154 bits (388), Expect = 6e-36
Identities = 75/184 (40%), Positives = 119/184 (64%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++P + ALEP+++DD AV++ G + +MCR++L +G+ +HFY++NL ++ V
Sbjct: 229 KAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHH-LHFYTMNLAQATRMV 287
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L P + +LPW+ + RR EDVRPIFW NR KSY+ RT WD+FPNGRW
Sbjct: 288 LEELNWAPSAERPLQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ + + GLT + A+R+ +G + QD+ +FVR+ + + LP
Sbjct: 348 GDSRSPAFGELDAYGI----GLTGTN--EANRKKWGEPKTVQDIAQLFVRYLRNEIDSLP 401
Query: 552 WVEA 563
W E+
Sbjct: 402 WSES 405
[96][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 152 bits (385), Expect = 1e-35
Identities = 80/189 (42%), Positives = 114/189 (60%), Gaps = 5/189 (2%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGL-----SPGIHFYS 167
MT FCKT+VP ++ LE ++ DD VK+ G+++ MC +I+ G+ S G+HFY+
Sbjct: 198 MTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYT 257
Query: 168 LNLEKSVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW 347
LNLE SV ++++L +V + R LPWRP+ R+ E+VRPIFW NR KS+++RTS+W
Sbjct: 258 LNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRPIFWRNRQKSFIQRTSSW 317
Query: 348 DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFF 527
D+FPNGR G+ S A+GD + R+ S+E QD VF F
Sbjct: 318 DEFPNGRLGNQASAAYGDF------------ELNFRSYSKE-------TQD--KVFTDFI 356
Query: 528 KGSLKRLPW 554
KG +KRLPW
Sbjct: 357 KGEVKRLPW 365
[97][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 152 bits (384), Expect = 2e-35
Identities = 79/191 (41%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K ++P + A+EPIRD+D A++ YG+ A M R + DSGL G+HFY+LN E + + +
Sbjct: 262 KLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQI 321
Query: 198 VDQLGLVPQTQSI-RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWG 374
+ Q+GL T+ I R PW+ R E+VRPIFWA+RPKSY+ RT WD+FPNGRWG
Sbjct: 322 LKQIGL--WTEDIQRPWPWKRTANYNRCEEEVRPIFWASRPKSYVYRTQEWDEFPNGRWG 379
Query: 375 DNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSE----QDVVDVFVRFFKG--- 533
+ SPAFG++++++L A EL G E QDV DVF + G
Sbjct: 380 SSESPAFGELNDYYLF------YLKPNAKKEELLDMWGHELTCLQDVCDVFTNYITGKES 433
Query: 534 ----SLKRLPW 554
++++PW
Sbjct: 434 KNGKKVRKIPW 444
[98][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 152 bits (384), Expect = 2e-35
Identities = 80/194 (41%), Positives = 120/194 (61%), Gaps = 13/194 (6%)
Frame = +3
Query: 12 FCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVM 191
+C +VP + L P+ DDD V+E G ++ DMCRR+L+SG+ +H Y++NLE+ +
Sbjct: 220 WCGVRVPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPL 279
Query: 192 AVVDQLGLVPQTQSIRSL-----------PWRPATLDKRRTEDVRPIFWANRPKSYLERT 338
++++LGL+P+ + +S+ PWR + +RR E+VRPIFW +RP SY+ RT
Sbjct: 280 VILERLGLLPEASAEQSIDTFTNEPPAVVPWRRSLNPQRRNEEVRPIFWKSRPYSYVART 339
Query: 339 SAW--DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDV 512
S W D+FPNGR+GD+ SPAFGD+ L GS L + R S EL+ S +DV +
Sbjct: 340 SQWAADEFPNGRFGDSSSPAFGDLD---LCGSTLLRQSAQR--SLELWAMPSSIRDVAML 394
Query: 513 FVRFFKGSLKRLPW 554
V + +G L+ LPW
Sbjct: 395 VVAYLQGELRCLPW 408
[99][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 152 bits (383), Expect = 2e-35
Identities = 74/181 (40%), Positives = 112/181 (61%), Gaps = 5/181 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+PP LEPI+DDD V+E G ++ + MC ++L SG +HFY++NLE++ + +++
Sbjct: 232 IPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMILET 291
Query: 207 LGLVPQTQSIRS-----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L ++ ++ + LPWR + +R E +RPIFW NR SY+ RT+ WD+FPNGRW
Sbjct: 292 LNIIEPVKAHENTGGDELPWRKSLHPQRSKETIRPIFWQNRKYSYITRTATWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L S L + +A +L+G + +D D+ V + +G LK LP
Sbjct: 352 GDSRSPAFGDID---LCASELLRQSPKKA--YDLWGTPQTLKDFSDIIVSYLQGELKSLP 406
Query: 552 W 554
W
Sbjct: 407 W 407
[100][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 151 bits (382), Expect = 3e-35
Identities = 76/181 (41%), Positives = 112/181 (61%), Gaps = 5/181 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P AL+PI+DDD V+E G ++ ++MC ++L SG +HFY++NLEK+ + ++++
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEK 291
Query: 207 LGLVPQTQSI-----RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L L+ +S LPWR + +R E +RPIFW +R SY+ RT+ WD+FPNGRW
Sbjct: 292 LNLIEAIKSHDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L S L + +A EL+G S D+ + + + KG LK LP
Sbjct: 352 GDSRSPAFGDID---LCASELLRQSPKKAF--ELWGLPQSLADLSGIIINYLKGDLKSLP 406
Query: 552 W 554
W
Sbjct: 407 W 407
[101][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 151 bits (382), Expect = 3e-35
Identities = 74/180 (41%), Positives = 116/180 (64%), Gaps = 2/180 (1%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+PP ALEP+++DD AV+ G + +MCR++L +G+ +HFY++NL+++ V+ +
Sbjct: 218 IPPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAGIHH-LHFYTMNLQQATKMVLGE 276
Query: 207 LGLVP--QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
L L+P +T + LPWR + RR EDVRPIFW +R +SY+ RT WD++PNGRW D+
Sbjct: 277 LELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDS 336
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
RSPAFG++ + G+ + +L+G S +++ ++FVRF G+L RLPW E
Sbjct: 337 RSPAFGELDTY------GIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSE 390
[102][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 151 bits (381), Expect = 4e-35
Identities = 76/182 (41%), Positives = 119/182 (65%), Gaps = 2/182 (1%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
+VP A LE +++DD AV++ G + DMCR+IL +G+ +HFY++NL ++ V++
Sbjct: 231 KVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAGIRH-LHFYTMNLAQATRMVLE 289
Query: 204 QLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+L +P ++LPW+ + RR EDVRPIFW NR KSY+ RT WD+FPNGRWGD
Sbjct: 290 ELDWLPSPDRPLKQALPWKQSLGFGRRDEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGD 349
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWV 557
+RSPAFG++ + + GLT ++ + +R+ +G S +D+ ++FVR+ ++ LPW
Sbjct: 350 SRSPAFGELDAYGV----GLTGSNEQ--NRKKWGEPTSIKDIANLFVRYLNKEIEYLPWS 403
Query: 558 EA 563
EA
Sbjct: 404 EA 405
[103][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 150 bits (380), Expect = 5e-35
Identities = 76/193 (39%), Positives = 117/193 (60%), Gaps = 12/193 (6%)
Frame = +3
Query: 12 FCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVM 191
+C+ VP L+ +DDD+ V+ G ++ DMC ++++SG +HFY++NLEKS +
Sbjct: 213 WCQINVPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLEKSTI 272
Query: 192 AVVDQLGLVPQ------------TQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLER 335
V+++L L+ +S ++PWR + R E +RPIFW+NR +Y+ R
Sbjct: 273 MVLEKLQLIDTHNQPVASVRDCGVESQVTVPWRRSLNPTRVNESIRPIFWSNRKFTYISR 332
Query: 336 TSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVF 515
TS WD+FPNGRWGD+RSPAFG++ L + ++ RA EL+G S DV+D+F
Sbjct: 333 TSNWDEFPNGRWGDSRSPAFGEVD---LCDGDLIRHSPKRAV--ELWGKPQSIDDVIDLF 387
Query: 516 VRFFKGSLKRLPW 554
VR+ +G+L LPW
Sbjct: 388 VRYLQGNLSSLPW 400
[104][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 150 bits (378), Expect = 8e-35
Identities = 75/181 (41%), Positives = 112/181 (61%), Gaps = 5/181 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P AL+PI+DDD V+E G ++ ++MC ++L SG +HFY++NLEK+ + ++++
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEK 291
Query: 207 LGLVPQTQSI-----RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L L+ +S LPWR + +R E +RPIFW +R SY+ RT+ WD+FPNGRW
Sbjct: 292 LNLIEAIKSHDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L S L + +A EL+G S ++ + + + KG LK LP
Sbjct: 352 GDSRSPAFGDID---LCASELLRQSPKKAF--ELWGLPQSLAELSGIIINYLKGDLKSLP 406
Query: 552 W 554
W
Sbjct: 407 W 407
[105][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 149 bits (376), Expect = 1e-34
Identities = 75/184 (40%), Positives = 116/184 (63%), Gaps = 7/184 (3%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P + LEP++DDD V++ G ++ DMC++IL+SG +H Y++NLEK+ + +++
Sbjct: 236 KIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILE 295
Query: 204 QLGLVPQTQSIR-----SLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--DDFPN 362
+LGL+P + SLPWR + KR+ E+VRPIFW RP SY+ RTS W D+FPN
Sbjct: 296 KLGLLPSESEVNANPLASLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAMDEFPN 355
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLK 542
GR+GD+ SPAFGD+ L GS + + + S EL+ + +DV + + + G +K
Sbjct: 356 GRFGDSSSPAFGDLD---LCGSTLIRQSGKK--SLELWSTPKTIEDVSQLVISYLTGQIK 410
Query: 543 RLPW 554
LPW
Sbjct: 411 CLPW 414
[106][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 148 bits (373), Expect = 3e-34
Identities = 72/184 (39%), Positives = 111/184 (60%), Gaps = 5/184 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P ALEPI++DD V+ G ++ ++MC +++ SG +HFY++NLE++ + +++
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILEN 291
Query: 207 LGLVPQTQSIR-----SLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L L+ +S LPWR + +R E +RPIFW NR SY+ RTS WD+FPNGRW
Sbjct: 292 LNLIESVKSHEVIGGSDLPWRKSLHPQRSKESIRPIFWQNRKYSYISRTSTWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L + L + +A +L+G G+ + D+ + F G L LP
Sbjct: 352 GDSRSPAFGDID---LFATDLLRQSPKKAF--DLWGHPGTLKQFSDIIISFLSGKLNSLP 406
Query: 552 WVEA 563
W ++
Sbjct: 407 WSDS 410
[107][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 148 bits (373), Expect = 3e-34
Identities = 73/188 (38%), Positives = 112/188 (59%), Gaps = 7/188 (3%)
Frame = +3
Query: 12 FCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVM 191
+C +P L+PI+DDD V+E G + +C+++LDSG +H Y++NLEK+
Sbjct: 231 WCDVHIPQEYFDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGYVSHLHIYTMNLEKAPQ 290
Query: 192 AVVDQLGLVPQ-----TQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--D 350
++D++ L+P + LPWR + +RR E+VRPIFW RP SY+ RTS W D
Sbjct: 291 MILDRMELLPSHDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWSVD 350
Query: 351 DFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFK 530
+FPNGR+GD+ SPAFGD+ L G+ + + + S EL+ S +D+ + + + +
Sbjct: 351 EFPNGRFGDSSSPAFGDLD---LCGASLIRQSGKK--SLELWSAPNSMEDIAQLVINYLR 405
Query: 531 GSLKRLPW 554
G LK LPW
Sbjct: 406 GELKYLPW 413
[108][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 148 bits (373), Expect = 3e-34
Identities = 72/184 (39%), Positives = 111/184 (60%), Gaps = 5/184 (2%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P ALEPI++DD V+ G ++ ++MC +++ SG +HFY++NLE++ + +++
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILEN 291
Query: 207 LGLVPQTQSIR-----SLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
L L+ +S LPWR + +R E +RPIFW NR SY+ RTS WD+FPNGRW
Sbjct: 292 LNLIESVKSHEVIGGSDLPWRKSLHPQRSKESIRPIFWQNRKYSYISRTSTWDEFPNGRW 351
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFGDI L + L + +A +L+G G+ + D+ + F G L LP
Sbjct: 352 GDSRSPAFGDID---LFATDLLRQSPKKAF--DLWGHPGTLKQFSDIIISFLSGKLNSLP 406
Query: 552 WVEA 563
W ++
Sbjct: 407 WSDS 410
[109][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 147 bits (370), Expect = 7e-34
Identities = 72/182 (39%), Positives = 118/182 (64%), Gaps = 2/182 (1%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P LEP+++DD AV++ G + ++CR+IL +G+ +HFY++NL ++ V++
Sbjct: 231 KIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHH-LHFYTMNLAQATRMVLE 289
Query: 204 QLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+L +P ++LPW+ + R+ EDVRPIFW NR KSY+ RT WD+FPNGRWGD
Sbjct: 290 ELDWMPSPDRPVKQALPWKRSLGLGRQVEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGD 349
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWV 557
+RSPAFG++ + + GLT + + +R+ +G +D+ ++FVR+ K ++ LPW
Sbjct: 350 SRSPAFGELDAYGI----GLTGTNEQ--NRQKWGEPTCIRDIANLFVRYLKKEIEYLPWS 403
Query: 558 EA 563
EA
Sbjct: 404 EA 405
[110][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 146 bits (368), Expect = 1e-33
Identities = 72/184 (39%), Positives = 117/184 (63%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
+ ++P ALEP+++DD AV+ G + +MCR++L +G+ +HFY++NL ++ +
Sbjct: 229 QAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHH-LHFYTMNLAQATRML 287
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
+++L P +LPW+ + RR EDVRPIFW NR KSY+ RT WD+FPNGRW
Sbjct: 288 LEELQWAPSADRPLQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRW 347
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ + + GLT ++ A+R+ +G + QD+ ++FV + ++ LP
Sbjct: 348 GDSRSPAFGELDAYGI----GLTGSN--EANRKKWGEPKAIQDIAELFVSYLNNKIESLP 401
Query: 552 WVEA 563
W E+
Sbjct: 402 WSES 405
[111][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 145 bits (367), Expect = 2e-33
Identities = 78/189 (41%), Positives = 116/189 (61%), Gaps = 9/189 (4%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P + LEPI+ DD AV++YG + +MCRR+LD+G +P IH Y++N E S+ ++
Sbjct: 267 EIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILK 326
Query: 204 QLGLVPQTQSIRSLPWRPATLDKRRT-EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
LGL + + R PW+ + R E VRPI+W+ RP+SY+ RT WD FPNGRWG++
Sbjct: 327 SLGLW-KLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNS 385
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS------- 536
SPAFGD+S+++L + NAD R A ++G I S +DV VF+ + +
Sbjct: 386 SSPAFGDVSSYYLSNLTTVRNADDRLA---MFGANIESFEDVKRVFINYITQAPNADGVK 442
Query: 537 LKRLPWVEA 563
+ LPW EA
Sbjct: 443 VTVLPWTEA 451
[112][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 145 bits (367), Expect = 2e-33
Identities = 78/189 (41%), Positives = 116/189 (61%), Gaps = 9/189 (4%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P + LEPI+ DD AV++YG + +MCRR+LD+G +P IH Y++N E S+ ++
Sbjct: 288 EIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILK 347
Query: 204 QLGLVPQTQSIRSLPWRPATLDKRRT-EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
LGL + + R PW+ + R E VRPI+W+ RP+SY+ RT WD FPNGRWG++
Sbjct: 348 SLGLW-KLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNS 406
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS------- 536
SPAFGD+S+++L + NAD R A ++G I S +DV VF+ + +
Sbjct: 407 SSPAFGDVSSYYLSNLTTVRNADDRLA---MFGANIESFEDVKRVFINYITQAPNADGVK 463
Query: 537 LKRLPWVEA 563
+ LPW EA
Sbjct: 464 VTVLPWTEA 472
[113][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 144 bits (364), Expect = 4e-33
Identities = 72/183 (39%), Positives = 111/183 (60%), Gaps = 7/183 (3%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + L+PI+DDD V++ G + +MC+++LDSG +H Y++NLEK+ + ++++
Sbjct: 48 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 107
Query: 207 LGLVPQTQSIRS-----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--DDFPNG 365
L ++P + LPWR + KR+ E+VRPIFW RP SY+ RTS W D+FPNG
Sbjct: 108 LNILPMESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNG 167
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
R+GD+ SPAFGD+ L GS + + + EL+ S DV + + + G+LK
Sbjct: 168 RFGDSSSPAFGDLD---LCGSDLIRQSANKCL--ELWSTPTSINDVAFLVINYLNGNLKC 222
Query: 546 LPW 554
LPW
Sbjct: 223 LPW 225
[114][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 144 bits (364), Expect = 4e-33
Identities = 72/183 (39%), Positives = 111/183 (60%), Gaps = 7/183 (3%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + L+PI+DDD V++ G + +MC+++LDSG +H Y++NLEK+ + ++++
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 207 LGLVPQTQSIRS-----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--DDFPNG 365
L ++P + LPWR + KR+ E+VRPIFW RP SY+ RTS W D+FPNG
Sbjct: 297 LNILPMESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNG 356
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
R+GD+ SPAFGD+ L GS + + + EL+ S DV + + + G+LK
Sbjct: 357 RFGDSSSPAFGDLD---LCGSDLIRQSANKCL--ELWSTPTSINDVAFLVINYLNGNLKC 411
Query: 546 LPW 554
LPW
Sbjct: 412 LPW 414
[115][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 144 bits (363), Expect = 5e-33
Identities = 72/183 (39%), Positives = 111/183 (60%), Gaps = 7/183 (3%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + L+PI+DDD V++ G + +MC+++LDSG +H Y++NLEK+ + ++++
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 207 LGLVPQTQSIRS-----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--DDFPNG 365
L ++P + LPWR + KR+ E+VRPIFW RP SY+ RTS W D+FPNG
Sbjct: 297 LNILPTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNG 356
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
R+GD+ SPAFGD+ L GS + + + EL+ S DV + + + G+LK
Sbjct: 357 RFGDSSSPAFGDLD---LCGSDLIRQSANKCL--ELWSTPTSINDVAFLVINYLNGNLKC 411
Query: 546 LPW 554
LPW
Sbjct: 412 LPW 414
[116][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 144 bits (363), Expect = 5e-33
Identities = 71/166 (42%), Positives = 108/166 (65%), Gaps = 2/166 (1%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++PP AALE +++DDAAV+ G + +MCRRI+++G+ +HFY++NL ++ V++
Sbjct: 231 KIPPKWSAALEEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHH-LHFYTMNLAQATRMVLE 289
Query: 204 QLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGD 377
+L L P Q +LPWR + RR EDVRPIFW NR KSY+ RT WD+FPNGRWGD
Sbjct: 290 ELSLTPSNQRPLKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGD 349
Query: 378 NRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVF 515
+RSPAFG++ + G+ + + +L+G S +D+ ++F
Sbjct: 350 SRSPAFGELDAY------GIGLKGSNEQNIKLWGQPKSIKDIAELF 389
[117][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 144 bits (363), Expect = 5e-33
Identities = 72/183 (39%), Positives = 111/183 (60%), Gaps = 7/183 (3%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + L+PI+DDD V++ G + +MC+++LDSG +H Y++NLEK+ + ++++
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 207 LGLVPQTQSIRS-----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW--DDFPNG 365
L ++P + LPWR + KR+ E+VRPIFW RP SY+ RTS W D+FPNG
Sbjct: 297 LNILPTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNG 356
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
R+GD+ SPAFGD+ L GS + + + EL+ S DV + + + G+LK
Sbjct: 357 RFGDSSSPAFGDLD---LCGSDLIRQSANKCL--ELWSTPTSINDVAFLVINYLNGNLKC 411
Query: 546 LPW 554
LPW
Sbjct: 412 LPW 414
[118][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 144 bits (362), Expect = 6e-33
Identities = 77/189 (40%), Positives = 115/189 (60%), Gaps = 9/189 (4%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P + LEPI+ DD AV++YG + +MCRR+LD+G +P IH Y++N E S+ ++
Sbjct: 289 EIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILK 348
Query: 204 QLGLVPQTQSIRSLPWRPATLDKRRT-EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
LGL + + R PW+ + R E VRPI+W+ RP+SY+ RT WD FPNGRWG++
Sbjct: 349 ALGLW-KLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNS 407
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS------- 536
SPAFGD+S+++L L N D R + ++G I S +DV VF+ + +
Sbjct: 408 SSPAFGDVSSYYLSNLTTLRNGDDRLS---MFGENIESIEDVKRVFINYITQTPNVSGKK 464
Query: 537 LKRLPWVEA 563
+ LPW EA
Sbjct: 465 VTVLPWTEA 473
[119][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 144 bits (362), Expect = 6e-33
Identities = 77/189 (40%), Positives = 115/189 (60%), Gaps = 9/189 (4%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P + LEPI+ DD AV++YG + +MCRR+LD+G +P IH Y++N E S+ ++
Sbjct: 339 EIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILK 398
Query: 204 QLGLVPQTQSIRSLPWRPATLDKRRT-EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
LGL + + R PW+ + R E VRPI+W+ RP+SY+ RT WD FPNGRWG++
Sbjct: 399 ALGLW-KLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNS 457
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS------- 536
SPAFGD+S+++L L N D R + ++G I S +DV VF+ + +
Sbjct: 458 SSPAFGDVSSYYLSNLTTLRNGDDRLS---MFGENIESIEDVKRVFINYITQTPNVSGKK 514
Query: 537 LKRLPWVEA 563
+ LPW EA
Sbjct: 515 VTVLPWTEA 523
[120][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 143 bits (361), Expect = 8e-33
Identities = 72/184 (39%), Positives = 112/184 (60%), Gaps = 2/184 (1%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
+ ++P LEPI+ DDAAV+ G ++ ++CR+IL +G+ +HFY++NL +S +
Sbjct: 224 QARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHH-LHFYTMNLAQSTALI 282
Query: 198 VDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
++ L +P +LPW+ + RR EDVRPIFW NR KSY+ RT WD+FPNGRW
Sbjct: 283 LEDLDWLPSPNKPLKHALPWKQSLGLGRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRW 342
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD+RSPAFG++ + G+ +R+ +G S +D+ +FVR+ + + LP
Sbjct: 343 GDSRSPAFGELDAY------GIGLLGTNEQNRKKFGEPKSVKDIATLFVRYVQKEVDTLP 396
Query: 552 WVEA 563
W E+
Sbjct: 397 WSES 400
[121][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 142 bits (357), Expect = 2e-32
Identities = 76/185 (41%), Positives = 117/185 (63%), Gaps = 8/185 (4%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
+VP + L+ ++D A++ +GI+ AT MC+ + SG GIH Y+LN+EK VM++++
Sbjct: 251 KVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILE 310
Query: 204 QLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNR 383
L + + + + LPW+ + D R EDVRPIFWA+RP+SYL RTS W+D PNGRWG++
Sbjct: 311 NLKISKEPE-LNKLPWQLS--DVRSGEDVRPIFWASRPRSYLIRTSNWEDMPNGRWGNSS 367
Query: 384 SPAFGDISNHHLVGSGGLTNADARAASRELYG-PIGSEQDVVDVFVRFFKG-------SL 539
S +FGD+ ++HL + G + D+ S ++G + SEQDV D+FV + G +
Sbjct: 368 SASFGDLKDYHLFLT-GTSRKDSELLS--MWGRELNSEQDVFDIFVCYLTGRDNKQGFKV 424
Query: 540 KRLPW 554
LPW
Sbjct: 425 TELPW 429
[122][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 140 bits (354), Expect = 5e-32
Identities = 77/188 (40%), Positives = 114/188 (60%), Gaps = 10/188 (5%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P S+ +LEPI++DD AV+ +GI A +CR +L +G + IH ++LN E S ++ Q
Sbjct: 287 IPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQ 346
Query: 207 LGLVPQTQSIRSLPWR--PATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDN 380
LGL P++ +R+LPWR + R EDVRPIFW+ RPKSY+ RT WD+FPNGRWG++
Sbjct: 347 LGLWPRSP-MRALPWRLFGESHPVRCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNS 405
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSL------ 539
SPAF D+ +++L G D + +YG + + D+ VFV F ++
Sbjct: 406 SSPAFNDLKDYYLFYLKGQPTRDEQL---RMYGERLETLADIQKVFVNFITQNINENGVK 462
Query: 540 -KRLPWVE 560
+LPW E
Sbjct: 463 VSQLPWNE 470
[123][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 140 bits (353), Expect = 7e-32
Identities = 76/191 (39%), Positives = 112/191 (58%), Gaps = 10/191 (5%)
Frame = +3
Query: 12 FCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVM 191
+C+ ++PP LEP++DDD AV+E G + DMCR+IL SG +H Y++NLE++ +
Sbjct: 230 WCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASL 289
Query: 192 AVVDQLGLVP--------QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAW 347
++++L L+ + + +L WR + RR E VRPIFW RP SY+ RTS W
Sbjct: 290 MILERLQLIDTGGAGVRRRPSTNETLTWRKSLNPTRRKEGVRPIFWQRRPYSYVARTSQW 349
Query: 348 --DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVR 521
D+FPNGR+GD+ SPA+GD+ L G L R S EL+ + D+ + +
Sbjct: 350 SADEFPNGRFGDSSSPAYGDLD---LCGHTVLRQTYQR--SLELWSTPRTLLDLAALVIS 404
Query: 522 FFKGSLKRLPW 554
+ KG LK LPW
Sbjct: 405 YLKGDLKCLPW 415
[124][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 140 bits (353), Expect = 7e-32
Identities = 72/194 (37%), Positives = 116/194 (59%), Gaps = 11/194 (5%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
T +C+ VP + LEP++DDD V++ G ++ ++C+++LDSG +H Y++NLEK+
Sbjct: 230 TQWCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLEKA 289
Query: 186 VMAVVDQLGLVPQT-------QSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSA 344
+ ++++L L+ ++ + + LPWR + KRR E VRPIFW RP SY+ RTS
Sbjct: 290 SLMILEKLDLLKRSNVGKDVIEPLEPLPWRKSLNPKRRNELVRPIFWQKRPYSYVARTSL 349
Query: 345 W--DDFPNGRWGDNRSPAFGDIS--NHHLVGSGGLTNADARAASRELYGPIGSEQDVVDV 512
W D+FPNGR+GD+ SPA+GD+ H L+ + S EL+ + D+ ++
Sbjct: 350 WNEDEFPNGRFGDSSSPAYGDLDLCGHSLI-------RQSVKKSIELWSTPQTLDDMSNL 402
Query: 513 FVRFFKGSLKRLPW 554
+ +G LK LPW
Sbjct: 403 VTSYLEGKLKCLPW 416
[125][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 138 bits (347), Expect = 3e-31
Identities = 75/187 (40%), Positives = 115/187 (61%), Gaps = 10/187 (5%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P ALEP++DDDA V+E G ++ +MC++++D+G++ +HFY++NLEK+ +++
Sbjct: 232 RIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITR-LHFYTMNLEKATKMIIE 290
Query: 204 QLGLVPQ---------TQSIRSLPWRPATLDKRR-TEDVRPIFWANRPKSYLERTSAWDD 353
++GL+ Q T IRS P + LD R E VRP+FW R +S++ RT WD+
Sbjct: 291 KMGLLNQYIETPKNELTSHIRS-PSQLQFLDNPRPNETVRPMFWKTRSQSFISRTEQWDE 349
Query: 354 FPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKG 533
FPNGRWGD+RSPAFG+ H GL DA R L+G + +D+ +VF + +
Sbjct: 350 FPNGRWGDSRSPAFGEFDPKH----HGLKQTDAEI--RALWGSPENIRDLGNVFAAYCER 403
Query: 534 SLKRLPW 554
L LPW
Sbjct: 404 KLACLPW 410
[126][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 126 bits (317), Expect = 1e-27
Identities = 63/152 (41%), Positives = 93/152 (61%), Gaps = 5/152 (3%)
Frame = +3
Query: 114 MCRRILDSGLSPGIHFYSLNLEKSVMAVVDQLGLVPQTQSIR-----SLPWRPATLDKRR 278
MC++++DS + +HFY++NLE++ + +++ L L+ + LPWR + R
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRKSLHPSRS 60
Query: 279 TEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARA 458
E +RPIFW NR SY+ RTS WD+FPNGRWGD+RSPAFGDI L + L + RA
Sbjct: 61 KESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDID---LFAADLLRQSPKRA 117
Query: 459 ASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
+L+G S +D+ ++ V + K LK LPW
Sbjct: 118 F--DLWGCPQSFKDLSNLVVSYLKNDLKSLPW 147
[127][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 126 bits (317), Expect = 1e-27
Identities = 63/152 (41%), Positives = 93/152 (61%), Gaps = 5/152 (3%)
Frame = +3
Query: 114 MCRRILDSGLSPGIHFYSLNLEKSVMAVVDQLGLVPQTQSIR-----SLPWRPATLDKRR 278
MC++++DS + +HFY++NLE++ + +++ L L+ + LPWR + R
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRKSLHPSRS 60
Query: 279 TEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARA 458
E +RPIFW NR SY+ RTS WD+FPNGRWGD+RSPAFGDI L + L + RA
Sbjct: 61 KESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGDID---LFAADLLRQSPKRA 117
Query: 459 ASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
+L+G S +D+ ++ V + K LK LPW
Sbjct: 118 F--DLWGCPQSFKDLSNLVVSYLKNDLKSLPW 147
[128][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 126 bits (317), Expect = 1e-27
Identities = 64/187 (34%), Positives = 109/187 (58%), Gaps = 10/187 (5%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
++P L P++DDD V+E G+++ +MCR+++ SG++ +HFY++NLEK+V +++
Sbjct: 231 KIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITR-LHFYTMNLEKAVKMIIE 289
Query: 204 QLGLVPQ-------TQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPN 362
+LGL+ + T ++ ++ D+R E VRPIFW R +SY+ RT WD+ P+
Sbjct: 290 RLGLLDENLAPIVDTNNVELT--NASSQDRRINEGVRPIFWRTRNESYVSRTDQWDELPH 347
Query: 363 GRWGDNRSPAFGDISNHHLVGSGGLTNADARAASREL---YGPIGSEQDVVDVFVRFFKG 533
GRWGD+RSPAFG+ R + +E+ +G S ++ D+F R+ +
Sbjct: 348 GRWGDSRSPAFGEFD---------AIRYGLRMSPKEITTSWGSPKSYSEIGDLFARYCEK 398
Query: 534 SLKRLPW 554
+ LPW
Sbjct: 399 KISSLPW 405
[129][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 106 bits (265), Expect = 1e-21
Identities = 68/207 (32%), Positives = 100/207 (48%), Gaps = 21/207 (10%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFYSLNL 176
+T ++PP + A +E + DD VK G+ + +++ I + + G HFY+LNL
Sbjct: 238 VTKLSHAKIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKISTPGHRGFHFYTLNL 297
Query: 177 EKSVMAVVDQLGLVP---QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPK--------- 320
EKSV ++++ L+P + S L + A D+ T A P
Sbjct: 298 EKSVSFILERCNLIPPSSEAPSDNELEFELAVSDRSSTVHETSALTAGYPALNPPNRNTT 357
Query: 321 -------SYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYG 479
L R + WDDFPNGRWGD RSPAFG+I G G + AR A R+L+G
Sbjct: 358 LQISEGLGSLGREATWDDFPNGRWGDARSPAFGEID-----GYGPSLHVTARVA-RKLWG 411
Query: 480 PIGSEQDVVDVFVRFFKGSLKRLPWVE 560
S +D+ ++F R G L +PW E
Sbjct: 412 TPTSREDISNIFRRLLSGELHAVPWSE 438
[130][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 104 bits (259), Expect = 5e-21
Identities = 73/213 (34%), Positives = 104/213 (48%), Gaps = 26/213 (12%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT CK QVP + ALEPI+ DDAAVKEYG+ ++ M RI G H SLNLEK
Sbjct: 287 MTNLCKVQVPQLILDALEPIKSDDAAVKEYGVSLSIHMVGRIFLETDVRGFHLCSLNLEK 346
Query: 183 SVMAVVDQLG----LVPQTQSIRSLPWRPATLDKRRTED--VRPIFWANRPKSY------ 326
S+ +++ LG + Q +S L PA L T++ + N PK +
Sbjct: 347 SIERILEGLGWKTDVGAQQESDARLRGIPAHLHLENTKNQMLSDRTGTNTPKDFKVTTQE 406
Query: 327 --------------LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAAS 464
+ TS WD+FPNGR+GD+RSPAFG++ G G + A
Sbjct: 407 ALARTLARTSSSYQVPETSTWDEFPNGRYGDSRSPAFGEMD-----GYGVSLKVPPQDAL 461
Query: 465 RELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
R ++G S D+ +F + + + +PW +A
Sbjct: 462 R-IWGHPVSLTDISRIFGFYLEEKISCIPWCDA 493
[131][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 97.1 bits (240), Expect = 8e-19
Identities = 57/192 (29%), Positives = 98/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEP-IRDDDAAVKEYGIKMATDMCRRILDS--GLSPGIHFYSLNL 176
T +PP+V P +R DD VK+ G+K+ D+ +I + G G HFY+LNL
Sbjct: 229 TNLSHASIPPAVGQLFPPDVRHDDDKVKDIGVKLMIDIVDQIYNETHGEVNGYHFYTLNL 288
Query: 177 EKSVMAVVDQLGLVPQTQSIRS----LPWRPATLDKRRTEDVRPIFWANRPKSYLERTSA 344
EKSV +VD+ L+ ++ S + +K + + + I + + + + +
Sbjct: 289 EKSVAQIVDKSSLLSPRLTVSSRFENAIESSSEDEKEQNQQTKTIIAISSGEGTMGKEAT 348
Query: 345 WDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRF 524
WDDFPNGR+GD+RSPA+G+I + G + + + + +L+G D+ +F+ +
Sbjct: 349 WDDFPNGRYGDSRSPAYGEIDGY------GPSLKVSSSRAYKLWGYPVDLDDITKIFIAY 402
Query: 525 FKGSLKRLPWVE 560
+ LPW E
Sbjct: 403 LSNRITALPWSE 414
[132][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 95.9 bits (237), Expect = 2e-18
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 55/240 (22%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFYSLNLE 179
T ++PP + + LE ++ DD AVK G+ + +D+ I + G HFY+LNLE
Sbjct: 239 TKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLE 298
Query: 180 KSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATLDK 272
K+V ++++ GL+P + S+ SLP +D+
Sbjct: 299 KTVSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDR 358
Query: 273 ---------RRTEDVRPIFWANRP---------------KSYLERTSAWDDFPNGRWGDN 380
R + P A P + L R + WDDFPNGRWGD
Sbjct: 359 LQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDA 418
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
RSPAFG+I + G + + A +R ++G S +D+ +F R G L +PW E
Sbjct: 419 RSPAFGEIDGY------GPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSE 472
[133][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 95.9 bits (237), Expect = 2e-18
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 55/240 (22%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFYSLNLE 179
T ++PP + + LE ++ DD AVK G+ + +D+ I + G HFY+LNLE
Sbjct: 266 TKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLE 325
Query: 180 KSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATLDK 272
K+V ++++ GL+P + S+ SLP +D+
Sbjct: 326 KTVSFIIERCGLIPDYPEDTDAVVDDDYTTAPTGAQNRSLSRRRASSVNSLPHNRVIVDR 385
Query: 273 ---------RRTEDVRPIFWANRP---------------KSYLERTSAWDDFPNGRWGDN 380
R + P A P + L R + WDDFPNGRWGD
Sbjct: 386 LQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDA 445
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
RSPAFG+I + G + + A +R ++G S +D+ +F R G L +PW E
Sbjct: 446 RSPAFGEIDGY------GPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSE 499
[134][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 95.1 bits (235), Expect = 3e-18
Identities = 59/163 (36%), Positives = 79/163 (48%), Gaps = 11/163 (6%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
+T C T+VP + L PI DD VK+YG+K+A M RR+ G G HF +LNLEK
Sbjct: 226 LTKLCGTRVPACITEDLAPISHDDQLVKDYGVKLAVQMIRRLRLEGGIQGFHFCTLNLEK 285
Query: 183 SVMAVVDQLGLVPQTQSIRSLPWR---------PATLDKRRTEDVRPIFWAN--RPKSYL 329
SV V++ L T P P + T + I + + L
Sbjct: 286 SVQRVLETLRWAGDTPGTMEPPAEMGPPDLLITPTSATDTATSTLATISVTDGEAGRGEL 345
Query: 330 ERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARA 458
+ WDDFPNGR+GD +SPAFG N L G G++ +D A
Sbjct: 346 NNAATWDDFPNGRFGDFKSPAFG---NQDLWGGSGISGSDVLA 385
[135][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 94.0 bits (232), Expect = 7e-18
Identities = 67/240 (27%), Positives = 103/240 (42%), Gaps = 55/240 (22%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFYSLNLE 179
T ++PP + + LE ++ DD AVK G+ + +D+ I + G HFY+LNLE
Sbjct: 239 TKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLE 298
Query: 180 KSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATLDK 272
K+V ++++ GL+P + S+ SLP +D+
Sbjct: 299 KTVSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDR 358
Query: 273 ---------RRTEDVRPIFWANRP---------------KSYLERTSAWDDFPNGRWGDN 380
R + P A P + L R + WDDFPNGRWGD
Sbjct: 359 LQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDA 418
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
RSPAFG+I + G + + A +R ++G S +D+ +F G L +PW E
Sbjct: 419 RSPAFGEIDGY------GPSLHVSGAVARRIWGYPVSREDISALFRHHVSGDLYIVPWSE 472
[136][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 93.2 bits (230), Expect = 1e-17
Identities = 72/242 (29%), Positives = 102/242 (42%), Gaps = 56/242 (23%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMAT---DMCRRILDSGLSPGIHFYSLN 173
+T Q+PP + A LE ++ DD +VK G+ + + D R I GL G HFY+LN
Sbjct: 286 VTKLSHVQIPPQILAKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLR-GFHFYTLN 344
Query: 174 LEKSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATL 266
LEK+V ++++ L+P + SI SLP +
Sbjct: 345 LEKTVSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIV 404
Query: 267 DKRRTEDVR---------PIFWANRPK---------------SYLERTSAWDDFPNGRWG 374
DK +V P A P L R + WDDFPNGRWG
Sbjct: 405 DKLHASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWG 464
Query: 375 DNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
D RSPAFG+I + G + A + ++G S +D+ +F R G L +PW
Sbjct: 465 DARSPAFGEIDGY------GPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPW 518
Query: 555 VE 560
E
Sbjct: 519 SE 520
[137][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 92.0 bits (227), Expect = 3e-17
Identities = 71/242 (29%), Positives = 102/242 (42%), Gaps = 56/242 (23%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMAT---DMCRRILDSGLSPGIHFYSLN 173
+T Q+PP + + LE ++ DD +VK G+ + + D R I GL G HFY+LN
Sbjct: 238 VTKLSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLR-GFHFYTLN 296
Query: 174 LEKSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATL 266
LEK+V ++++ L+P + SI SLP +
Sbjct: 297 LEKTVSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIV 356
Query: 267 DKRRTEDVR---------PIFWANRPK---------------SYLERTSAWDDFPNGRWG 374
DK +V P A P L R + WDDFPNGRWG
Sbjct: 357 DKLHASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWG 416
Query: 375 DNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
D RSPAFG+I + G + A + ++G S +D+ +F R G L +PW
Sbjct: 417 DARSPAFGEIDGY------GPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPW 470
Query: 555 VE 560
E
Sbjct: 471 SE 472
[138][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 92.0 bits (227), Expect = 3e-17
Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
+T C T+VP +++A L PI++DD VK+YG+K A R+ + G G HF +LNLEK
Sbjct: 223 LTKLCGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIHRLRNEGGIQGFHFCTLNLEK 282
Query: 183 SVMAVVDQL----GLVPQTQSIRSLPWRPATLDKRRTED---VRPIFWANRPKSYLERT- 338
SV V+++L G+VP Q+ + + P L + + + P N S L +
Sbjct: 283 SVQRVLEELKWRTGVVPAVQN-KLIADSPDALSQNTLDSNLLITPTSATNVATSVLTTSV 341
Query: 339 -------------------SAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAA 461
+ WDDFPNGR+GD +SPAFG + G GGL +RA
Sbjct: 342 LGTVSRTLPEAGRGELNDAATWDDFPNGRFGDFKSPAFG--NQDPWGGPGGL--GISRAE 397
Query: 462 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
+ + +G + D+ +F+ + P+
Sbjct: 398 ALQQWGYPKTFDDLTRIFLAHLHSEIPITPF 428
[139][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 91.7 bits (226), Expect = 4e-17
Identities = 63/187 (33%), Positives = 82/187 (43%), Gaps = 1/187 (0%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M C P V LEPI+ DDA VKE+GI ++ DM + I + H Y+LNLEK
Sbjct: 251 MANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLEK 310
Query: 183 SVMAVVDQLGLVP-QTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFP 359
S V+ L VP Q+ SI + WD+FP
Sbjct: 311 SATCVIKVLADVPDQSASISG-------------------------------SVTWDEFP 339
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGR+ D RSPAFG++ G G A R L+G E D+ +F RF G L
Sbjct: 340 NGRYTDARSPAFGEMD-----GYGANLKVPPEEAVR-LWGTPVDEDDISSIFSRFVDGRL 393
Query: 540 KRLPWVE 560
+PW +
Sbjct: 394 ACMPWCD 400
[140][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 91.3 bits (225), Expect = 5e-17
Identities = 65/243 (26%), Positives = 106/243 (43%), Gaps = 58/243 (23%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD-SGLSPG---IHFYSLN 173
T ++PP++ A L+ ++ DD VK G+ + ++M RI + +PG HFY+LN
Sbjct: 241 TKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKSRTPGPRGFHFYTLN 300
Query: 174 LEKSVMAVVDQLGLVPQ-------------------------TQSIRSLPWRPATL---- 266
LEK+V + ++ L+P T+SI+ L R ++
Sbjct: 301 LEKAVAFIAERTNLIPPGTPDEDESAILPDIPQLRINGSSVPTRSIQDLSTRKGSIGSDP 360
Query: 267 -DKRRTEDVRP------------------------IFWANRPKSYLERTSAWDDFPNGRW 371
D+ + RP + + L R + WDDFPNGRW
Sbjct: 361 RDRVIVANQRPSHPDYEASPSEAGLPAEPVNTRANTLAISEGEGVLGREATWDDFPNGRW 420
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD RSPA+G I + G++ + +L+G + +D+ +F+R KG L +P
Sbjct: 421 GDARSPAYGQIDGY------GVSLHVTVPQALQLWGSPKTTEDINKIFIRHLKGELSAIP 474
Query: 552 WVE 560
W E
Sbjct: 475 WSE 477
[141][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/114 (40%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Frame = +3
Query: 168 LNLEKSVMAVVDQLGLVPQTQSI--RSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTS 341
+NL ++ V+++L +P ++ ++LPW+ + RR EDVRPIFW R KSY+ RT
Sbjct: 1 MNLAQATRMVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQ 60
Query: 342 AWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDV 503
WD+FPNGRWGD+RSPAFG++ + + GLT + + + +G + QD+
Sbjct: 61 DWDEFPNGRWGDSRSPAFGELDAYGI----GLTGTNEQNIKK--WGEPQTVQDI 108
[142][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 90.5 bits (223), Expect = 8e-17
Identities = 71/243 (29%), Positives = 104/243 (42%), Gaps = 57/243 (23%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMC---RRILDSGLSPGIHFYSLN 173
+T QVPP + + LE +R DD AVK G+ + T++ R+I + G G HFY+LN
Sbjct: 238 VTKLSHVQVPPHILSKLEAVRHDDDAVKRIGVDVITNLVDGIRKIPNPGFR-GFHFYTLN 296
Query: 174 LEKSVMAVVDQLGL------------------VPQTQSIRSLPWRPAT-----------L 266
LEK+V ++++ GL VP +R+L R A+ +
Sbjct: 297 LEKTVSFIIERCGLIPDDAENSAAVDEDDYATVPSGAQLRALTRRRASSVHSQAHNRVIV 356
Query: 267 DKRR-------------------------TEDVRPIFWANRPKSYLERTSAWDDFPNGRW 371
DK + D + L R + WDDFPNGRW
Sbjct: 357 DKLQKPSDGSSRASTTHEALANSAGMPAMAPDRNTTLQISEGLGALGREATWDDFPNGRW 416
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD RSPAFG+I + G + + +R ++G S D+ +F R G L +P
Sbjct: 417 GDARSPAFGEIDGY------GPSLHVSPTVARRVWGYPVSRDDISTLFRRHVSGELYIVP 470
Query: 552 WVE 560
W E
Sbjct: 471 WSE 473
[143][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 89.7 bits (221), Expect = 1e-16
Identities = 64/243 (26%), Positives = 105/243 (43%), Gaps = 58/243 (23%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS----PGIHFYSLN 173
T ++P ++ L+ +R DD VK+ G+ + ++M + + G HFY+LN
Sbjct: 244 TKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFYTLN 303
Query: 174 LEKSVMAVVDQLGLVPQTQSIRSL-----PWRPATLD------------KRRTEDV---- 290
LEK+V ++++ L+P +++ +L P P D RR V
Sbjct: 304 LEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHKRSSRRRSSVGSDP 363
Query: 291 ------------RPIFWANRPKS---------------------YLERTSAWDDFPNGRW 371
P F A ++ L R + WDDFPNGRW
Sbjct: 364 YNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPNGRW 423
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD RSPA+G+I + G++ + + +L+G S D+ D+F+R +G L +P
Sbjct: 424 GDARSPAYGEIDGY------GVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIP 477
Query: 552 WVE 560
W E
Sbjct: 478 WSE 480
[144][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 89.4 bits (220), Expect = 2e-16
Identities = 39/76 (51%), Positives = 60/76 (78%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MTGFCKT++P + AALEPI+D++ AVK YGI + T+MC++IL G++ +H Y+LN+EK
Sbjct: 234 MTGFCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINT-LHLYTLNMEK 292
Query: 183 SVMAVVDQLGLVPQTQ 230
S +A++ LGL+ +T+
Sbjct: 293 SALAILMNLGLIEETK 308
[145][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 89.4 bits (220), Expect = 2e-16
Identities = 64/243 (26%), Positives = 105/243 (43%), Gaps = 58/243 (23%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS----PGIHFYSLN 173
T ++P ++ L+ +R DD VK+ G+ + ++M + + G HFY+LN
Sbjct: 244 TKLSHAKLPTNIIRRLDEVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFYTLN 303
Query: 174 LEKSVMAVVDQLGLVPQTQSIRSL-----PWRPATLD------------KRRTEDV---- 290
LEK+V ++++ L+P +++ +L P P D RR V
Sbjct: 304 LEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHRRSSRRRSSVGSDP 363
Query: 291 ------------RPIFWA---------------------NRPKSYLERTSAWDDFPNGRW 371
P F A + + L R + WDDFPNGRW
Sbjct: 364 YNRIIITAPQTSNPSFEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPNGRW 423
Query: 372 GDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLP 551
GD RSPA+G+I + G++ + + +L+G S D+ D+F+R +G L +P
Sbjct: 424 GDARSPAYGEIDGY------GVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIP 477
Query: 552 WVE 560
W E
Sbjct: 478 WSE 480
[146][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 89.4 bits (220), Expect = 2e-16
Identities = 68/244 (27%), Positives = 99/244 (40%), Gaps = 59/244 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSLNLE 179
T +VPP + A +E ++ DD VK G+ + ++ + G HFY+LNLE
Sbjct: 239 TKLSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLE 298
Query: 180 KSVMAVVDQLGLVP--------------------------------QTQSIRSLPWRPAT 263
K+V V++ L+P + S+ S P
Sbjct: 299 KAVALTVEKCNLIPPLSPLSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLI 358
Query: 264 LDK---------RRTEDVRPIFWANRPK----------------SYLERTSAWDDFPNGR 368
+D+ T P A P L R + WDDFPNGR
Sbjct: 359 VDRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGR 418
Query: 369 WGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRL 548
WGD RSPAFG+I G G + +A A +R L+G ++QD+ ++F R G L +
Sbjct: 419 WGDARSPAFGEID-----GYGPSLHVNA-AVARRLWGYPTTKQDINNIFQRHVSGELHLV 472
Query: 549 PWVE 560
PW E
Sbjct: 473 PWSE 476
[147][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 89.0 bits (219), Expect = 2e-16
Identities = 63/226 (27%), Positives = 100/226 (44%), Gaps = 45/226 (19%)
Frame = +3
Query: 21 TQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMA 194
+ +P +++ L+ DD AVK GI++ TDM +I + +G G HFY LNLEK+V +
Sbjct: 235 SSIPHEIESQLQNTSSDDNAVKSIGIRIITDMVDQINNRSNGAIRGYHFYCLNLEKAVAS 294
Query: 195 VVDQLGLV------------------PQTQSIRSLPWR---------------------- 254
V+DQ ++ + I P +
Sbjct: 295 VLDQSAVLRPIMEAPTNTISHDDAVASDDEDIEMPPKKGRRRSSIINENEVAAPGFAAVG 354
Query: 255 ---PATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVG 425
A+ +K D R + + K L + + WDDFPNGR+GD+ SPA+G+I G
Sbjct: 355 MGHKASANKALLSDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEID-----G 409
Query: 426 SGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
G + + +G S +D+ VF+ + G + LPWV+A
Sbjct: 410 YGPSLKIHSPQEAIAKWGTPESTKDISKVFLNYLSGKINILPWVDA 455
[148][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 89.0 bits (219), Expect = 2e-16
Identities = 68/245 (27%), Positives = 99/245 (40%), Gaps = 60/245 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSLNLE 179
T +VPP + A +E ++ DD VK G+ + ++ + G HFY+LNLE
Sbjct: 239 TKLSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLE 298
Query: 180 KSVMAVVDQLGLVP---------------------------------QTQSIRSLPWRPA 260
K+V V++ L+P + S+ S P
Sbjct: 299 KAVALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRL 358
Query: 261 TLDK---------RRTEDVRPIFWANRPK----------------SYLERTSAWDDFPNG 365
+D+ T P A P L R + WDDFPNG
Sbjct: 359 IVDRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNG 418
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
RWGD RSPAFG+I G G + +A A +R L+G ++QD+ ++F R G L
Sbjct: 419 RWGDARSPAFGEID-----GYGPSLHVNA-AVARRLWGYPTTKQDINNIFQRHVSGELHL 472
Query: 546 LPWVE 560
+PW E
Sbjct: 473 VPWSE 477
[149][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 89.0 bits (219), Expect = 2e-16
Identities = 68/245 (27%), Positives = 99/245 (40%), Gaps = 60/245 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSLNLE 179
T +VPP + A +E ++ DD VK G+ + ++ + G HFY+LNLE
Sbjct: 239 TKLSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLE 298
Query: 180 KSVMAVVDQLGLVP---------------------------------QTQSIRSLPWRPA 260
K+V V++ L+P + S+ S P
Sbjct: 299 KAVALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRL 358
Query: 261 TLDK---------RRTEDVRPIFWANRPK----------------SYLERTSAWDDFPNG 365
+D+ T P A P L R + WDDFPNG
Sbjct: 359 IVDRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNG 418
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
RWGD RSPAFG+I G G + +A A +R L+G ++QD+ ++F R G L
Sbjct: 419 RWGDARSPAFGEID-----GYGPSLHVNA-AVARRLWGYPTTKQDINNIFQRHVSGELHL 472
Query: 546 LPWVE 560
+PW E
Sbjct: 473 VPWSE 477
[150][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 89.0 bits (219), Expect = 2e-16
Identities = 69/239 (28%), Positives = 99/239 (41%), Gaps = 53/239 (22%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNL 176
+T +PP + +E ++ DD AVK G+ + +++ + D S G HFY+LNL
Sbjct: 239 VTKLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGVRDIPSPGPRGFHFYTLNL 298
Query: 177 EKSVMAVVDQLGLVP-----------------------------QTQSIRSLPWRPATLD 269
EK+V +++Q L+P + SI S P +D
Sbjct: 299 EKTVSFILEQCDLIPSYSDAGDTAIADDPASIPLDFPGRALRRRRASSINSQPHNRVIVD 358
Query: 270 KRRTEDVR--------------PIFWANRPKSYL--------ERTSAWDDFPNGRWGDNR 383
K + P NR + L R + WDDFPNGRWGD R
Sbjct: 359 KLSVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDAR 418
Query: 384 SPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
SPAFG+I G G + A A R L+G +D+ +F R G L +PW E
Sbjct: 419 SPAFGEID-----GYGPSLHVTANTA-RRLWGHPVDSKDMSAIFRRHVSGELHMVPWSE 471
[151][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 89.0 bits (219), Expect = 2e-16
Identities = 69/244 (28%), Positives = 107/244 (43%), Gaps = 59/244 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD----SGLSP-GIHFYSL 170
T ++P ++ LE +R DD VKE G+ + +++ +I + + P G HFY+L
Sbjct: 262 TKLSHAKIPDALMDRLEAVRGDDERVKEVGVDIVSELVEQIKEIKGRTAEGPKGFHFYTL 321
Query: 171 NLEKSVMAVVDQLGLV-PQT-------QSIRSLPWRPATL---------DKRRTEDVRP- 296
NLEK+V +V++ GL+ P+T ++R P L D RR +
Sbjct: 322 NLEKAVSFIVERTGLIPPETPEEDELQSAVRHNPLPDIRLLRINGSVPDDGRRKGSIGSD 381
Query: 297 ----IFWANRPKSY--------------------------------LERTSAWDDFPNGR 368
+ R SY L R + WDDFPNGR
Sbjct: 382 PRDRVIIQGRSTSYPDWEATAQEASIPAEPINSRANTLAISEGEGVLGREATWDDFPNGR 441
Query: 369 WGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRL 548
WGD RSPA+G I + G++ A + ++G + +D+ +VF+R KG L +
Sbjct: 442 WGDARSPAYGQIDGY------GVSLHVTVAQALRIWGTPRTTEDINNVFIRHLKGELTTI 495
Query: 549 PWVE 560
PW E
Sbjct: 496 PWSE 499
[152][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 89.0 bits (219), Expect = 2e-16
Identities = 63/226 (27%), Positives = 100/226 (44%), Gaps = 45/226 (19%)
Frame = +3
Query: 21 TQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMA 194
+ +P +++ L+ DD AVK GI++ TDM +I + +G G HFY LNLEK+V +
Sbjct: 235 SSIPHEIESQLQNTSSDDNAVKSIGIRIITDMVDQINNRSNGAIRGYHFYCLNLEKAVAS 294
Query: 195 VVDQLGLV------------------PQTQSIRSLPWR---------------------- 254
V+DQ ++ + I P +
Sbjct: 295 VLDQSAVLRPIMEAPTNTISHDDAVASDDEDIEMPPKKGRRRSSIINENEVAAPGFAAVG 354
Query: 255 ---PATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVG 425
A+ +K D R + + K L + + WDDFPNGR+GD+ SPA+G+I G
Sbjct: 355 MGHKASANKALLSDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEID-----G 409
Query: 426 SGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
G + + +G S +D+ VF+ + G + LPWV+A
Sbjct: 410 YGPSLKIHSPQEAIAKWGTPESTKDISKVFLNYLSGKINILPWVDA 455
[153][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 87.8 bits (216), Expect = 5e-16
Identities = 65/221 (29%), Positives = 97/221 (43%), Gaps = 39/221 (17%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
+ K VP S+ + L+PI DDA VK YG ++AT M +I++SGL PG+H +LNLEK
Sbjct: 227 LVNLTKCPVPDSITSDLQPISSDDATVKRYGAELATKMVSQIIESGLVPGVHLCTLNLEK 286
Query: 183 SVMAVVDQLGLVPQTQS----------------------------------IRSLPWRPA 260
SV ++D LG +++ ++L P+
Sbjct: 287 SVRMILDNLGWSAASKTSEDEGLVKNKLIEDDGQARKGIPINGKAGTAQSPAKNLSISPS 346
Query: 261 TLDKRRTEDVRPIFWANRPKSYLERTSA-----WDDFPNGRWGDNRSPAFGDISNHHLVG 425
++ + PK+ L A WD+FPNGR+ D RSPA+G+I G
Sbjct: 347 EANQLAQLGLTSTTLPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEID-----G 401
Query: 426 SGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRL 548
G A A +E P+ S D+ +F + K L
Sbjct: 402 WGSGLKITAAQALKEWGVPV-STSDLSALFTAYLHSDPKHL 441
[154][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 87.8 bits (216), Expect = 5e-16
Identities = 65/238 (27%), Positives = 100/238 (42%), Gaps = 52/238 (21%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMC---RRILDSGLSPGIHFYSLN 173
+T ++PP + A L+ ++ DD AVK G+ + ++ +++ GL G HFY+LN
Sbjct: 238 VTKLSHVKIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKLPTPGLR-GFHFYTLN 296
Query: 174 LEKSVMAVVDQLGLVP---------------------------QTQSIRSLPWRPATLDK 272
LEK+V ++++ L+P + SI SLP +DK
Sbjct: 297 LEKTVSFILERCKLIPDHDDDAEAVADGVSLLTVDAEIANRRRRASSISSLPHNRVIVDK 356
Query: 273 RRT----------------------EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRS 386
D + L R + WDDFPNGRWGD RS
Sbjct: 357 VSNGSSKDSVTHEATAASAGLPAGPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS 416
Query: 387 PAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
PAFG+I + G + A + + ++G S D+ +F R G L +PW E
Sbjct: 417 PAFGEIDGY------GPSLHVAPSVAHRIWGYPVSTDDISKLFRRHVSGDLHMVPWSE 468
[155][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 85.1 bits (209), Expect = 3e-15
Identities = 70/250 (28%), Positives = 102/250 (40%), Gaps = 64/250 (25%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD---SGLSPGIHFYSLN 173
+T ++PP + + LE +R DD AVK G+ + D+ + D GL G HFY+LN
Sbjct: 238 VTKLSHVKIPPQILSRLEEVRHDDDAVKRIGVDILKDLVDGMRDIPCPGLR-GFHFYTLN 296
Query: 174 LEKSVMAVVDQLGLVP--------------------------------------QTQSIR 239
LEK+V ++++ L+P + SI
Sbjct: 297 LEKTVSFILERCDLIPPYTEAGDEDALVDGGSLSALDSSSYVAPNGIPIRTLARRRSSIN 356
Query: 240 SLPWRPATLDKRRTEDVR--------PIFWANRPKSYLERTSA---------------WD 350
SLP +D+ + + P A P +RT+ WD
Sbjct: 357 SLPHNRVIVDREVSNESSKDSVSHEAPATSAGVPAMPPDRTTTLQISEGLGALGREATWD 416
Query: 351 DFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFK 530
DFPNGRWGD RSPAFG+I G G + A R ++G + D+ +F R
Sbjct: 417 DFPNGRWGDARSPAFGEID-----GYGPSLHVTPSVAHR-IWGYPVTRDDINTLFRRHVS 470
Query: 531 GSLKRLPWVE 560
G L +PW E
Sbjct: 471 GELHMVPWSE 480
[156][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 84.3 bits (207), Expect = 6e-15
Identities = 69/249 (27%), Positives = 107/249 (42%), Gaps = 63/249 (25%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFYSLNL 176
+T +PP++ + +E +R DD VK+ G+ + +++ +I L + G HFY+LNL
Sbjct: 238 VTKLSAAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKALPNPGQRGYHFYTLNL 297
Query: 177 EKSVMAV---------------------VDQLGLVPQ----------TQSIRSLPWRPAT 263
EKSV + ++Q+G Q SI S P
Sbjct: 298 EKSVTLILESCDLIPPCNDDSAVEDGFAIEQVGSNNQDLKTLVSRRRASSINSGPHNRVI 357
Query: 264 LDKRRTEDVRPIFWANR--------------------PKSY----------LERTSAWDD 353
+DK + ++R P+S L R + WDD
Sbjct: 358 VDKLHVPTDQQSEHSSRKSITYETLASNAGVPALNPPPRSTQLQISEGIGSLGREATWDD 417
Query: 354 FPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKG 533
FPNGRWGD+RSPAFG+I G G + +A A +EL+G + +D+ +F + G
Sbjct: 418 FPNGRWGDSRSPAFGEID-----GYGPSLHVNATVA-KELWGFPVTREDIGTLFRKHVSG 471
Query: 534 SLKRLPWVE 560
L +PW E
Sbjct: 472 ELYIVPWSE 480
[157][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 83.6 bits (205), Expect = 1e-14
Identities = 60/214 (28%), Positives = 99/214 (46%), Gaps = 36/214 (16%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + E I++DD AVK+ G+ + D+ RI + G HFY+LNLEK+V ++++Q
Sbjct: 238 IPRPILHEFETIKNDDDAVKQLGVDLICDIIDRIDEHTNIKGYHFYTLNLEKAVASIMNQ 297
Query: 207 LGLVPQTQSIRSLPWRPAT------------------------------------LDKRR 278
+Q +R + P+T L R
Sbjct: 298 ------SQVLRGVLEGPSTSSEISKNEDAIASDSEDESPKHFRRRSSVNEVARGSLSFHR 351
Query: 279 TEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARA 458
+D + I +R K L + + WDDFPNGR+GD+ SPA+G+I + S + NA
Sbjct: 352 QKDKKSIVDISRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYG--PSLKIHNASEAI 409
Query: 459 ASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
A +G + +++ VFV + G + +PW +
Sbjct: 410 AK---WGSPTNIKELGQVFVDYLSGKIDVVPWAD 440
[158][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 82.4 bits (202), Expect = 2e-14
Identities = 61/220 (27%), Positives = 98/220 (44%), Gaps = 34/220 (15%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M C +P + +LE +R DD VK G+K M + IL + + G HF +LNLEK
Sbjct: 234 MARLCNCVIPHDLMQSLEEVRTDDEKVKAIGVKHVAQMIKDILKNTDTRGFHFCTLNLEK 293
Query: 183 SVMAVVDQLGLVP------------QTQSIRSLPWR---------PATL--------DKR 275
SV ++++ GL Q +++ + R P+ DK+
Sbjct: 294 SVARILNESGLYERRLTALKAVVNNQKENVADVHNRVVIPKKDHLPSAFEGLYIRADDKQ 353
Query: 276 RTE-----DVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLT 440
T + + + L R + WDD+ NGR+GD RSPA+G+I + G +
Sbjct: 354 FTRTAEFFEKQASISVSEGTGALGREATWDDYTNGRFGDPRSPAYGNIDGY------GPS 407
Query: 441 NADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
A S +L+G E D+ ++F R G +PW++
Sbjct: 408 LHFAPEESLKLWGYPVDEDDITNIFKRHVLGETTAIPWID 447
[159][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 82.0 bits (201), Expect = 3e-14
Identities = 54/216 (25%), Positives = 98/216 (45%), Gaps = 38/216 (17%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + ++ + DD AVK G+++ +++ RI G HFY+LNLEK+V +++D+
Sbjct: 238 IPREISQQVDKVSHDDDAVKALGVEILSNIIDRIDKETNIKGYHFYTLNLEKAVASILDK 297
Query: 207 LGLV------PQT---------------------QSI-----------RSLPWRPATLDK 272
++ P T Q++ SL A + K
Sbjct: 298 SDVLRPILEGPSTVMEHDDAIASDSDDDEDMNTGQAVSVTRRRSSINDNSLMGSKALIGK 357
Query: 273 RRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADA 452
+D + + + K L + + WDDFPNGR+GD+ SPA+G+I G G +
Sbjct: 358 ALLKDKKTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEID-----GYGPTLKIHS 412
Query: 453 RAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
A + +G + +D+ +F+ + G + +PW +
Sbjct: 413 PAEAEIKWGSPETTKDLAQIFIDYLSGKIDVIPWAD 448
[160][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 81.3 bits (199), Expect = 5e-14
Identities = 65/255 (25%), Positives = 108/255 (42%), Gaps = 70/255 (27%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD----SGLSPGIHFYSLN 173
T ++P + A L+ ++ DD VK+ G+ + +++ ++ + S G HFY+LN
Sbjct: 212 TKLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLN 271
Query: 174 LEKSV-------------------MAVVDQL--------GLVPQTQSIRSLPWRPAT-LD 269
LEK+V +AVVD + G P + P T +
Sbjct: 272 LEKAVSFIVERTNLIPATTPDDDEVAVVDDVALPSIHLNGATPAKDHLSVSSLHPPTHTN 331
Query: 270 KRRTEDV------RPIFWANRPKSY--------------------------------LER 335
RR + R I + RP S+ L R
Sbjct: 332 SRRPSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGR 391
Query: 336 TSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVF 515
+ WDD+PNGRWGD RSPA+G+I + G++ + + +L+G + +DV ++F
Sbjct: 392 EATWDDYPNGRWGDARSPAYGEIDGY------GVSLHMSGTQAVQLWGRPATVEDVSNIF 445
Query: 516 VRFFKGSLKRLPWVE 560
+R +G+L +PW E
Sbjct: 446 MRHLRGALPAIPWSE 460
[161][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 79.0 bits (193), Expect = 2e-13
Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 45/224 (20%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + ++ + DD AVK G+ + ++M +I S G HFY+LNLEK+V +++D+
Sbjct: 238 IPKEILKQVDQVCHDDNAVKALGVDILSEMIDQIDKSTTIKGYHFYTLNLEKAVASILDK 297
Query: 207 LGLVPQ-----------------------------------TQSIR----------SLPW 251
++ Q T++I+ L
Sbjct: 298 SDVLRQVLEGPSYATRFEDAVASDSDDEDEPEKASERDITLTKTIKPRRVSSINDNELTS 357
Query: 252 RPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSG 431
A + K D + + + K L + + WDDFPNGR+GD+ SPA+G+I G G
Sbjct: 358 SKALVGKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEID-----GYG 412
Query: 432 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
A + +G S D+ VF+ + G + +PW ++
Sbjct: 413 PTLKIHTPAEASTKWGTPESIADLTQVFINYLSGKVDVVPWADS 456
[162][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 79.0 bits (193), Expect = 2e-13
Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 45/224 (20%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + ++ + DD AVK G+ + ++M +I S G HFY+LNLEK+V +++D+
Sbjct: 238 IPKEILKQVDQVCHDDNAVKALGVDILSEMIDQIDKSTTIKGYHFYTLNLEKAVASILDK 297
Query: 207 LGLVPQ-----------------------------------TQSIR----------SLPW 251
++ Q T++I+ L
Sbjct: 298 SDVLRQVLEGSSYATRFEDAVASDSDDEDEPEKASERDITLTKTIKPRRVSSINDNELTS 357
Query: 252 RPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSG 431
A + K D + + + K L + + WDDFPNGR+GD+ SPA+G+I G G
Sbjct: 358 SKALVGKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEID-----GYG 412
Query: 432 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
A + +G S D+ VF+ + G + +PW ++
Sbjct: 413 PTLKIHTPAEASTKWGTPESIADLTQVFINYLSGKVDVVPWADS 456
[163][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 78.6 bits (192), Expect = 3e-13
Identities = 63/235 (26%), Positives = 98/235 (41%), Gaps = 49/235 (20%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDS--GLSPGIHFYSLNL 176
MT C VP S+ L + DD A+K G++ DM ++I+D+ G G HF +LNL
Sbjct: 234 MTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGFHFCTLNL 293
Query: 177 EKSVMAVVDQLGLVPQ-----------------TQSIRSL------------PWRPATLD 269
E+SV ++ GL+ + T+ SL P + D
Sbjct: 294 ERSVALILKNSGLLTKRWKQVESEMEDEKLLRTTRKRLSLDEPAELHNQVVVPSQQPVAD 353
Query: 270 K------------------RRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAF 395
K TE+ F + L R + WDDF NGR+GD RSPA+
Sbjct: 354 KSSNLFVTSKQSSVSGHKDNLTEEAP--FSVSEGSGVLGRQANWDDFTNGRFGDPRSPAY 411
Query: 396 GDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
G+I + G T + + +L+G E D+ +F + + +PW++
Sbjct: 412 GEIDGY------GPTLHFPPSEALKLWGYPVDESDITSLFQKHIMSDISAIPWID 460
[164][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 77.8 bits (190), Expect = 5e-13
Identities = 64/240 (26%), Positives = 100/240 (41%), Gaps = 55/240 (22%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRIL--DSGLSPGIHFYSLNLE 179
T ++P + A L+ ++ DD VK+ G+++ +M I G HFY+LNLE
Sbjct: 242 TKLSHARLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKARPETCRRGFHFYTLNLE 301
Query: 180 KSVMAVV------------DQLGLVPQTQSIRSLPWRPATLDKRR--------------- 278
K+V VV D+ +V T +I P + +RR
Sbjct: 302 KAVSHVVEDTHLIPTTIMDDEEIIVETTPAINLEPPPNGLMARRRRSSAVNSGPFNRVII 361
Query: 279 ---------------TEDVRPI-----------FWANRPKSYLERTSAWDDFPNGRWGDN 380
TE+ + + + L R + WDDFPNGRWGD
Sbjct: 362 SHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGDA 421
Query: 381 RSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
RSPAFG+I + G T + + +L+G ++D+ +F R +G L+ +PW E
Sbjct: 422 RSPAFGEIDGY------GPTLHVSTPQALKLWGYPVEKKDISTLFRRHIEGDLEAIPWSE 475
[165][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 76.6 bits (187), Expect = 1e-12
Identities = 62/232 (26%), Positives = 98/232 (42%), Gaps = 46/232 (19%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS---PGIHFYSLNL 176
T +P + ++L DD VK GI + ++ +I DS G HFY LNL
Sbjct: 231 TKLSHASIPLEIQSSLHSSSYDDDLVKNIGIDVINNIINKI-DSNTDNRIKGYHFYCLNL 289
Query: 177 EKSVMAVVDQLGLVPQTQSIRSLPWR----------------PA-TLDKRRTE------- 284
EK+V ++++ ++ +S+ LP PA T+ RR +
Sbjct: 290 EKAVASIINDSDVL---KSVMDLPDETNNNEDAIASDSDEDLPAVTISNRRRKSSIINDN 346
Query: 285 -------------------DVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDIS 407
D R + + K L + + WDDFPNGR+GD+ SPA+G+I
Sbjct: 347 ELADKSNAQKSLVGKALIGDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEID 406
Query: 408 NHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
G G + + +G S +++ VFV + G + LPWV+A
Sbjct: 407 -----GYGPTLKIYSPEEAIHKWGAPESVNEIIKVFVSYLSGKIDSLPWVDA 453
[166][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 76.6 bits (187), Expect = 1e-12
Identities = 36/70 (51%), Positives = 49/70 (70%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
M FCKT+VP ++ A +E I+DD AAVK +G++ +MCR +L SG +HFY+LNLEK
Sbjct: 307 MAKFCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEK 366
Query: 183 SVMAVVDQLG 212
V V+D LG
Sbjct: 367 VVYGVLDALG 376
[167][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 76.6 bits (187), Expect = 1e-12
Identities = 62/232 (26%), Positives = 98/232 (42%), Gaps = 46/232 (19%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLS---PGIHFYSLNL 176
T +P + ++L DD VK GI + ++ +I DS G HFY LNL
Sbjct: 231 TKLSHASIPLEIQSSLHSSSYDDDLVKNIGIDVINNIINKI-DSNTDNRIKGYHFYCLNL 289
Query: 177 EKSVMAVVDQLGLVPQTQSIRSLPWR----------------PA-TLDKRRTE------- 284
EK+V ++++ ++ +S+ LP PA T+ RR +
Sbjct: 290 EKAVASIINDSDVL---KSVMDLPDETNNNEDAIASDSDEDLPAVTISNRRRKSSIINDN 346
Query: 285 -------------------DVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDIS 407
D R + + K L + + WDDFPNGR+GD+ SPA+G+I
Sbjct: 347 ELADKSNAQKSLVGKALIGDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEID 406
Query: 408 NHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
G G + + +G S +++ VFV + G + LPWV+A
Sbjct: 407 -----GYGPTLKIYSPEEAIHKWGAPESVNEIIKVFVSYLSGKIDSLPWVDA 453
[168][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 76.3 bits (186), Expect = 2e-12
Identities = 59/229 (25%), Positives = 104/229 (45%), Gaps = 51/229 (22%)
Frame = +3
Query: 27 VPPSV-DAALEPIRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMAV 197
+P +V D + I++DD VK G+ + D+ I +G HFY+LNLEK+V +
Sbjct: 241 IPKAVLDRFPQEIQNDDGIVKSIGVDVLIDIIEEIYSKTNGRVKCFHFYTLNLEKAVAQI 300
Query: 198 VDQLGLVP---------------------------------------QTQSIRS-LPWRP 257
V Q + Q+ S+ + + +
Sbjct: 301 VSQSSTLSKILEESDNEEDQVVSQDEDGDIVLVDQHEENPLKFKRRRQSSSVSADVIFNR 360
Query: 258 ATLDKRRTE--------DVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNH 413
A +++ +T+ + + +R L R + WD+FPNGR+GD+RSPA+G+I +
Sbjct: 361 AIINRGKTDRNESSELASKKLVVSISRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGY 420
Query: 414 HLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
G + + + EL+G S +D+ VFV++ +GS++ LPW +
Sbjct: 421 ------GPSLKVSNKRAYELWGSPTSIRDLKAVFVKYLEGSIQSLPWCD 463
[169][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 75.9 bits (185), Expect = 2e-12
Identities = 57/217 (26%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P ++ LE +D A+K G+++ +D+ I G HFY+LNLEK+V +++
Sbjct: 238 IPKTISRKLEASVGNDDAIKSLGVEIVSDIINTITSKTSIKGFHFYTLNLEKAVASILKN 297
Query: 207 LGLVPQT---------QSIR----------------------SLPWRPATLDKRRT---- 281
V QT +SI SL + L +R+
Sbjct: 298 -STVMQTIMERASSTEESINDDAIASSDEEEGKRKSSIINENSLSDKSLALSAQRSLVGK 356
Query: 282 ---EDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADA 452
+D + + + K L + + WDDFPNGR+GD+ SPA+G+I G G +
Sbjct: 357 ALLKDKKVLVDISTGKGALGKEAIWDDFPNGRFGDSNSPAYGEID-----GYGPSLKVAS 411
Query: 453 RAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
+ +G S D+ VF+ + G + LPW ++
Sbjct: 412 PEEAIAKWGSPESVGDIAKVFMGYLSGKIDILPWTDS 448
[170][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 75.5 bits (184), Expect = 3e-12
Identities = 56/224 (25%), Positives = 92/224 (41%), Gaps = 45/224 (20%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
+P + ++ + DD AVK G+ + T++ RI S G HFY+LNLEK+V +++D+
Sbjct: 238 IPRGILKQVDQVCHDDNAVKALGVDILTEIIDRIDKSTNIRGYHFYTLNLEKAVASILDK 297
Query: 207 LGLVPQT-------------------------------------------QSIRS--LPW 251
++ Q SI L
Sbjct: 298 SDVLRQVLEGPSYAARFEDAVVSDSDDENEQENPPEGDVTLAKTNKPRRISSINDNELTS 357
Query: 252 RPATLDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSG 431
A + K D + + + K L + + WDDFPNGR+GD+ SPA+G+I G G
Sbjct: 358 NKALVSKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEID-----GYG 412
Query: 432 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA 563
+ +G S D+ VF+ + G + +PW ++
Sbjct: 413 PTLKIHTPEEASTKWGTPESLADLTRVFINYLSGKVDVIPWADS 456
[171][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 75.1 bits (183), Expect = 3e-12
Identities = 31/66 (46%), Positives = 48/66 (72%)
Frame = +3
Query: 18 KTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAV 197
K +VP + +EPI+D+DAA++ YG+++A MCR +LDSG+ G+HFY+LN E + V
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 198 VDQLGL 215
+ +LGL
Sbjct: 335 LKRLGL 340
[172][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 74.3 bits (181), Expect = 6e-12
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 45/212 (21%)
Frame = +3
Query: 60 IRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMAVVDQLGLVPQT-- 227
IR DD VKE G+++ ++ ++ + SG HFY+LNLEKS+ +V Q ++ +
Sbjct: 249 IRHDDLKVKEIGVEIMVEIVNKVWERTSGRIKCFHFYTLNLEKSIAQIVTQSPVLSRIID 308
Query: 228 ------------------------------QSIRSLPWRPAT----LDKRRTEDVRP--- 296
+ S+ P + LD R VR
Sbjct: 309 EDSEVEDSSGDVVVEDANASEADDLSYKKRRRQSSMQGEPESGMVMLDGPRRFSVRGAVP 368
Query: 297 ----IFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAAS 464
+ ++ L R + WD+FPNGR+GD+RSPA+G+I + G + + +
Sbjct: 369 SRKVVISISKGSGTLGRDATWDEFPNGRFGDSRSPAYGEIDGY------GPSLKVSNKKA 422
Query: 465 RELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
+++G + D+ +F+ + +GS++ LPW +
Sbjct: 423 YQIWGYPSTLNDIKSLFIGYLEGSIEALPWCD 454
[173][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 74.3 bits (181), Expect = 6e-12
Identities = 55/214 (25%), Positives = 95/214 (44%), Gaps = 49/214 (22%)
Frame = +3
Query: 60 IRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMAVV----------- 200
++ DD VKE G+++ ++ +I + +G HFY+LNLE+++ +V
Sbjct: 259 VQSDDNRVKEIGVEILIEIIEQIHEKTNGRIKAFHFYTLNLERAIAQIVAKSPTLSKILE 318
Query: 201 ------DQLGLVPQTQSIRSLPWRPATLDKRRTED---------------VRPIFWANRP 317
D+ Q + SL + KR+ + + + NR
Sbjct: 319 EEDEADDEWDSDVVLQDVDSLTLDDDNIKKRKRQSSASTDFPLNTSIINKLNGMSHGNRV 378
Query: 318 KSY---------------LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADA 452
S L R WD+FPNGR+GD+RSPA+G+I + G +
Sbjct: 379 PSVPSRKVMISISQGTGVLGRNVTWDEFPNGRFGDSRSPAYGEIDGY------GPSLKVC 432
Query: 453 RAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
+ + EL+ S +D+ ++F+R+ +GS+K LPW
Sbjct: 433 NSTAYELWDHPVSLEDIKNIFIRYLEGSMKALPW 466
[174][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 73.9 bits (180), Expect = 8e-12
Identities = 33/71 (46%), Positives = 52/71 (73%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT FCKT+VP S++ ++ I+DD AVK++G++ ++ R +LDSG+ +HFY+LNLEK
Sbjct: 246 MTKFCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKI-LHFYTLNLEK 304
Query: 183 SVMAVVDQLGL 215
V + D+LG+
Sbjct: 305 VVYGITDELGI 315
[175][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 70.9 bits (172), Expect = 6e-11
Identities = 63/247 (25%), Positives = 102/247 (41%), Gaps = 62/247 (25%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILD-SGLSPG---IHFYSLN 173
T ++P + L+ ++ DD VK G+ + ++ +I D +PG HFY+LN
Sbjct: 241 TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN 300
Query: 174 LEKSV-------------------MAVVDQLGLVPQTQ---SIRSLPWRPATLDKRRTED 287
LEK+V + VD+L +P Q ++RS + +R +
Sbjct: 301 LEKAVSFILERANLIPDPPENEEAVVAVDELA-IPALQINGNMRSSSHSRSRQSRRHSSV 359
Query: 288 VRP----IFWANRPKSYLE--------------------------------RTSAWDDFP 359
+ +RP Y E R + WDDFP
Sbjct: 360 ASDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFP 419
Query: 360 NGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSL 539
NGR+GD RSPA+G+I + + +T A +L+ + QD+ D+FV+ +G L
Sbjct: 420 NGRFGDARSPAYGEIDGYGVSLHMSVTQA------VKLWDYPKTRQDINDLFVKHIQGEL 473
Query: 540 KRLPWVE 560
+PW E
Sbjct: 474 SAIPWSE 480
[176][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 70.9 bits (172), Expect = 6e-11
Identities = 59/231 (25%), Positives = 97/231 (41%), Gaps = 53/231 (22%)
Frame = +3
Query: 27 VPPSVDAALEP-IRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNLEKSVMAV 197
+P + P I+ DD AVK G+++ ++ I SG HFY+LNLEK+ +
Sbjct: 239 IPQHISERFSPEIQADDHAVKAVGVEILIEIINEIYQRTSGRIKVFHFYTLNLEKATAQI 298
Query: 198 VDQLGLVP---------------------------------QTQSIR--------SLPWR 254
V L+ QT R S+
Sbjct: 299 VTGCPLLSHILEEDQDDDSLIDNEDVIMTDDKGGENDVELGQTNKRRRHSSVNSNSMASG 358
Query: 255 PATLDKR--RTEDV-------RPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDIS 407
P +D+ R + + + + ++ L R + WD+FPNGR+GD+RSPA+G+I
Sbjct: 359 PLVIDRSGLRRDSIGLTVPSRKVLISISQGSGTLGRNATWDEFPNGRFGDSRSPAYGEID 418
Query: 408 NHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE 560
+ G+ A +L+G S D+ VF+++ +GS+ LPW +
Sbjct: 419 GYGPTLKVGIKKA------YDLWGTPKSVIDLKSVFIKYLEGSISALPWCD 463
[177][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 70.5 bits (171), Expect = 8e-11
Identities = 62/245 (25%), Positives = 98/245 (40%), Gaps = 60/245 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSP--GIHFYSL--- 170
T +VPP++ A +E ++ DD +VK G+ + ++ + + G+HFY+L
Sbjct: 239 TKLSHARVPPNIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLE 298
Query: 171 -------------------------NLEKSVMAVVDQLGLVPQ-----TQSIRSLPWRPA 260
+L+ +V V QL + + SI S P
Sbjct: 299 KAVAFTVERCSLIPPSSEPSSDSEADLDTAVSMVHGQLNNIVRMSKRRASSINSQPHNRL 358
Query: 261 TLDK-------------RRTEDVRPIFWANRPK------------SYLERTSAWDDFPNG 365
+D+ T+ + A P L R + WDDFPNG
Sbjct: 359 IVDRPSDGRGSSQASTTHETQTLGAGMPALNPPHRATTLQISEGVGALGREATWDDFPNG 418
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
RWGD RSPAFG+I + G + A +R L+G +++D+ +F R G L
Sbjct: 419 RWGDARSPAFGEIDGY------GPSLHVTPAVARRLWGYPTTKEDINTIFQRHVSGDLHI 472
Query: 546 LPWVE 560
+PW E
Sbjct: 473 VPWSE 477
[178][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 68.6 bits (166), Expect = 3e-10
Identities = 42/132 (31%), Positives = 61/132 (46%)
Frame = +3
Query: 165 SLNLEKSVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSA 344
SLN + ++D+ + Q+ + + A + + L R +
Sbjct: 351 SLNSQPYNRVIIDRADMSSQSSTTHETSAQGAGMPALNPPPRNTTLLISEGMGALGREAT 410
Query: 345 WDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRF 524
WDDFPNGRWGD RSPAFG+I G G + A A R L+G S +D+ +F R
Sbjct: 411 WDDFPNGRWGDARSPAFGEID-----GYGPSLHVTANVA-RRLWGFPTSREDINQIFRRH 464
Query: 525 FKGSLKRLPWVE 560
G+L +PW E
Sbjct: 465 VSGALHAVPWSE 476
[179][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 68.6 bits (166), Expect = 3e-10
Identities = 63/251 (25%), Positives = 105/251 (41%), Gaps = 65/251 (25%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRI--LDSGLSPGIHFY---- 164
+T +PP++ + +E +R DD VK+ G+ + +++ +I L + G HFY
Sbjct: 238 VTKLSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIVNQIKSLPNPGHRGYHFYTLNL 297
Query: 165 ----SLNLEKSVM--------AVVDQLGLVP-----------------QTQSIRSLPWRP 257
+L LE+ + AV D + + + S+ S P+
Sbjct: 298 EKSVTLILERCDLIPPSSDDDAVEDDIAIEEVAVSNNKDDLKTLVSRRRASSVNSGPYNR 357
Query: 258 ATLDKRRTEDVRPIFWANR--------------------PKSY----------LERTSAW 347
+DK + ++R P+S L R + W
Sbjct: 358 VIVDKLHVPTDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATW 417
Query: 348 DDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFF 527
DDFPNGRWGD+RSPAFG+I G G + +A A ++L+G + +D+ +F +
Sbjct: 418 DDFPNGRWGDSRSPAFGEID-----GYGPSLHVNATVA-KQLWGFPVTREDIGALFRKHV 471
Query: 528 KGSLKRLPWVE 560
G L +PW E
Sbjct: 472 SGELYIVPWSE 482
[180][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 67.8 bits (164), Expect = 5e-10
Identities = 60/245 (24%), Positives = 98/245 (40%), Gaps = 60/245 (24%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMAT---DMCRRILDSGLS--PGIHFYSL 170
T ++P ++ A L+ ++ DD VKE G+ + + D R + + G HFY+L
Sbjct: 241 TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL 300
Query: 171 N--------LEKSVM----------AVVDQLGLVPQTQSIRSLPWRPATLDK--RRTEDV 290
N LE++ + AV+D P +++ P + + RR +
Sbjct: 301 NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI 360
Query: 291 -----------------------------RPI------FWANRPKSYLERTSAWDDFPNG 365
PI + + L R + WDDFPNG
Sbjct: 361 GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG 420
Query: 366 RWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKR 545
RWGD RSPA+G+I + + +T A L+G S D+ +F++ +G L
Sbjct: 421 RWGDARSPAYGEIDGYGVSLHMSVTQA------VRLWGHPKSSVDISTLFIKHIRGELSA 474
Query: 546 LPWVE 560
+PW E
Sbjct: 475 IPWSE 479
[181][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 65.9 bits (159), Expect = 2e-09
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEK 182
MT FCK++ P ++ AA+E DD A+++ ++ +CR + +G +PG+HFY+LNLEK
Sbjct: 257 MTAFCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAG-APGLHFYTLNLEK 315
Query: 183 SVMAVVDQLGL 215
+A++D L L
Sbjct: 316 VTLAILDALNL 326
[182][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 65.9 bits (159), Expect = 2e-09
Identities = 41/132 (31%), Positives = 60/132 (45%)
Frame = +3
Query: 165 SLNLEKSVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSA 344
SLN + +VD+ + Q+ + A + + L R +
Sbjct: 353 SLNSQPHNRVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREAT 412
Query: 345 WDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRF 524
WDDFPNGRWGD RSPAFG+I G G + A A R L+G + +D+ ++F +
Sbjct: 413 WDDFPNGRWGDARSPAFGEID-----GYGPSLHVTANVA-RRLWGYPTTREDINNIFRQH 466
Query: 525 FKGSLKRLPWVE 560
G L +PW E
Sbjct: 467 VSGGLHAVPWSE 478
[183][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 65.9 bits (159), Expect = 2e-09
Identities = 33/78 (42%), Positives = 46/78 (58%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGRWGD RSPAFG+I + G T + + +L+G +QD+
Sbjct: 294 LGREATWDDFPNGRWGDARSPAFGEIDGY------GPTLHVSTTQALKLWGHPVDKQDIS 347
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F + +G L+ LPW E
Sbjct: 348 ALFRKHLEGELEALPWSE 365
[184][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 65.9 bits (159), Expect = 2e-09
Identities = 41/132 (31%), Positives = 60/132 (45%)
Frame = +3
Query: 165 SLNLEKSVMAVVDQLGLVPQTQSIRSLPWRPATLDKRRTEDVRPIFWANRPKSYLERTSA 344
SLN + +VD+ + Q+ + A + + L R +
Sbjct: 353 SLNSQPHNRVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREAT 412
Query: 345 WDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRF 524
WDDFPNGRWGD RSPAFG+I G G + A A R L+G + +D+ ++F +
Sbjct: 413 WDDFPNGRWGDARSPAFGEID-----GYGPSLHVTANVA-RRLWGYPTTREDINNIFRQH 466
Query: 525 FKGSLKRLPWVE 560
G L +PW E
Sbjct: 467 VSGGLHAVPWSE 478
[185][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 65.5 bits (158), Expect = 3e-09
Identities = 31/78 (39%), Positives = 48/78 (61%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WD+FPNGR+GD RSPAFG+I + G T + + EL+G + QD+
Sbjct: 396 LGRDATWDEFPNGRFGDTRSPAFGEIDGY------GPTLKVSNKKAYELWGQPKTIQDLQ 449
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F+++ +GS+ LPW +
Sbjct: 450 IIFIKYLEGSIDALPWCD 467
[186][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 65.5 bits (158), Expect = 3e-09
Identities = 34/78 (43%), Positives = 45/78 (57%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGRWGD RSPAFG+I G G + A A +R ++G + +D+
Sbjct: 410 LGREATWDDFPNGRWGDARSPAFGEID-----GYGPSLHVSA-ATARRIWGYPVTREDIS 463
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F R G L +PW E
Sbjct: 464 TLFRRHVSGELHMVPWSE 481
Score = 55.8 bits (133), Expect = 2e-06
Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGI---HFYSLN 173
+T ++PP V + LE ++ DD AVK G+ + +D+ I D +SPG+ HFY+LN
Sbjct: 238 VTKLSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIISDLVHGIRDL-VSPGLRGFHFYTLN 296
Query: 174 LEKSVMAVVDQLGLVP 221
LEK+V ++++ L+P
Sbjct: 297 LEKTVSFILERCELIP 312
[187][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 65.1 bits (157), Expect = 4e-09
Identities = 32/78 (41%), Positives = 47/78 (60%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGR+GD RSPA+G+I + + +T A +L+G + QD+
Sbjct: 411 LGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSITQA------VKLWGHPKTRQDIN 464
Query: 507 DVFVRFFKGSLKRLPWVE 560
D+FV+ +G L +PW E
Sbjct: 465 DLFVKHIQGQLSAIPWSE 482
[188][TOP]
>UniRef100_A4FAF8 Methylenetetrahydrofolate reductase n=1 Tax=Saccharopolyspora
erythraea NRRL 2338 RepID=A4FAF8_SACEN
Length = 294
Score = 64.7 bits (156), Expect = 5e-09
Identities = 30/65 (46%), Positives = 44/65 (67%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
VPP+V LEP+ DD AA + G+ +AT++C R++ G+ P +HFY+LN K+ VV
Sbjct: 228 VPPAVLERLEPLADDAAAFRAEGVVLATELCERLIAEGV-PALHFYTLNRSKATREVVSN 286
Query: 207 LGLVP 221
LGL+P
Sbjct: 287 LGLLP 291
[189][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 64.7 bits (156), Expect = 5e-09
Identities = 35/78 (44%), Positives = 46/78 (58%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGRWGD RSPAFG+I G G + +A A R+L+G S++D+
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEID-----GYGPSLHVNANVA-RQLWGYPTSKEDIN 462
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F G L +PW E
Sbjct: 463 KLFHCHVSGELHIVPWSE 480
[190][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 64.3 bits (155), Expect = 6e-09
Identities = 35/78 (44%), Positives = 45/78 (57%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGRWGD RSPAFG+I G G + +A A R+L+G S +D+
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEID-----GYGPSLHVNANVA-RQLWGYPTSREDIN 462
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F G L +PW E
Sbjct: 463 KLFHCHVSGELHIVPWSE 480
[191][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 64.3 bits (155), Expect = 6e-09
Identities = 35/78 (44%), Positives = 45/78 (57%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WDDFPNGRWGD RSPAFG+I G G + +A A R+L+G S +D+
Sbjct: 409 LGREATWDDFPNGRWGDARSPAFGEID-----GYGPSLHVNANVA-RQLWGYPTSREDIN 462
Query: 507 DVFVRFFKGSLKRLPWVE 560
+F G L +PW E
Sbjct: 463 KLFHCHVSGELHIVPWSE 480
[192][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 63.9 bits (154), Expect = 8e-09
Identities = 58/227 (25%), Positives = 92/227 (40%), Gaps = 51/227 (22%)
Frame = +3
Query: 27 VPPSV-DAALEPIRDDDAAVKEYGIKMATDMCRRILD--SGLSPGIHFYSLNL------- 176
+P ++ D + DD V+ G+ + +M I G GIHFY+LNL
Sbjct: 257 IPQAIRDRLPQEYHSDDNKVRAIGVDILVEMVEEIYKRTEGRIKGIHFYTLNLEKAIAQI 316
Query: 177 ---------------EKSVMAVVDQLGLVP---------------QTQSIRSLPWRPATL 266
E ++ V ++ LV Q+ L L
Sbjct: 317 VTKSPSLSKILEEDKEDDLVEGVGEIALVDGNTLEEDENVKKRRRQSSHNDDLTCNRVLL 376
Query: 267 DKR-------RTEDVRP----IFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNH 413
D+ R P + ++ L + + WD+F NGR+GD+RSPAFG+I
Sbjct: 377 DEAGKSIASGRESSGAPSRKVVISISQGSGALGKDATWDEFTNGRFGDSRSPAFGEID-- 434
Query: 414 HLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPW 554
G G ++ A E++G S D+ +F+R+ +GSL+ LPW
Sbjct: 435 ---GYGPSLKVSSKKA-YEIWGQPSSTDDIKTLFIRYLEGSLEALPW 477
[193][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 62.4 bits (150), Expect = 2e-08
Identities = 28/76 (36%), Positives = 49/76 (64%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WD+FPNGR+GD+RSPA+G+I + G + +++ + EL+G + D+
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGY------GPSIKVSKSKALELWGIPKTIGDLK 455
Query: 507 DVFVRFFKGSLKRLPW 554
D+F+++ +GS +PW
Sbjct: 456 DIFIKYLEGSTDAIPW 471
[194][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 62.4 bits (150), Expect = 2e-08
Identities = 28/76 (36%), Positives = 49/76 (64%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WD+FPNGR+GD+RSPA+G+I + G + +++ + EL+G + D+
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGY------GPSIKVSKSKALELWGIPKTIGDLK 455
Query: 507 DVFVRFFKGSLKRLPW 554
D+F+++ +GS +PW
Sbjct: 456 DIFIKYLEGSTDAIPW 471
[195][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 62.4 bits (150), Expect = 2e-08
Identities = 28/76 (36%), Positives = 49/76 (64%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WD+FPNGR+GD+RSPA+G+I + G + +++ + EL+G + D+
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGY------GPSIKVSKSKALELWGIPKTIGDLK 455
Query: 507 DVFVRFFKGSLKRLPW 554
D+F+++ +GS +PW
Sbjct: 456 DIFIKYLEGSTDAIPW 471
[196][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 62.4 bits (150), Expect = 2e-08
Identities = 28/76 (36%), Positives = 49/76 (64%)
Frame = +3
Query: 327 LERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLTNADARAASRELYGPIGSEQDVV 506
L R + WD+FPNGR+GD+RSPA+G+I + G + +++ + EL+G + D+
Sbjct: 402 LGRDATWDEFPNGRFGDSRSPAYGEIDGY------GPSIKVSKSKALELWGIPKTIGDLK 455
Query: 507 DVFVRFFKGSLKRLPW 554
D+F+++ +GS +PW
Sbjct: 456 DIFIKYLEGSTDAIPW 471
[197][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 60.5 bits (145), Expect = 9e-08
Identities = 24/67 (35%), Positives = 46/67 (68%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C T++P + LE DD +++ +G+++ T++CRR+L+ G +PG+HFY++N + +
Sbjct: 55 CGTEIPRWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEGG-APGLHFYTMNQSEPTLR 113
Query: 195 VVDQLGL 215
+ D+LGL
Sbjct: 114 LCDRLGL 120
[198][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 60.1 bits (144), Expect = 1e-07
Identities = 27/68 (39%), Positives = 44/68 (64%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
+ C +P + ++PIRDD AVK GI++A CR +L +G+ PG+HFY+LN ++
Sbjct: 181 SSMCGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGV-PGLHFYTLNKSEA 239
Query: 186 VMAVVDQL 209
+A+ +QL
Sbjct: 240 TIAIRNQL 247
[199][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 59.3 bits (142), Expect = 2e-07
Identities = 26/69 (37%), Positives = 44/69 (63%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +P + LE DD A++ +G+++ T++CRR+L+ G +PG+HFY+LN ++ +
Sbjct: 221 CGADIPRWIRKRLEAFGDDRKAIRTFGLEVVTELCRRLLEQG-APGLHFYTLNRAEACLE 279
Query: 195 VVDQLGLVP 221
V LGL P
Sbjct: 280 VWKALGLEP 288
[200][TOP]
>UniRef100_Q0VL81 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax borkumensis
SK2 RepID=Q0VL81_ALCBS
Length = 275
Score = 58.9 bits (141), Expect = 3e-07
Identities = 27/67 (40%), Positives = 43/67 (64%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C VP + + L I+DDDAAVK +G ++ T +C R+L G +PG+HFY++N +
Sbjct: 210 CGADVPRWLQSKLNDIKDDDAAVKAFGEEVVTRLCERLLAMG-APGLHFYTMNQAGPNLR 268
Query: 195 VVDQLGL 215
++D LG+
Sbjct: 269 ILDNLGM 275
[201][TOP]
>UniRef100_UPI000187F1CC hypothetical protein MPER_14139 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187F1CC
Length = 65
Score = 55.1 bits (131), Expect(2) = 4e-07
Identities = 23/51 (45%), Positives = 38/51 (74%), Gaps = 1/51 (1%)
Frame = +3
Query: 114 MCRRILDSGLS-PGIHFYSLNLEKSVMAVVDQLGLVPQTQSIRSLPWRPAT 263
MCR IL++ L G+HFY++NLEK ++++L LVP+ ++++ LPWR A+
Sbjct: 1 MCRTILNANLGIHGLHFYTMNLEKGTKMLLEELNLVPRVETLKPLPWRQAS 51
Score = 23.1 bits (48), Expect(2) = 4e-07
Identities = 8/20 (40%), Positives = 14/20 (70%)
Frame = +2
Query: 263 PGQASDGGCAAHLLGQPAEV 322
P + + G +AHLLG+P ++
Sbjct: 46 PWRQASGNDSAHLLGEPNQI 65
[202][TOP]
>UniRef100_A4T0E8 Methylenetetrahydrofolate reductase n=1 Tax=Polynucleobacter
necessarius subsp. asymbioticus QLW-P1DMWA-1
RepID=A4T0E8_POLSQ
Length = 276
Score = 58.2 bits (139), Expect = 4e-07
Identities = 26/67 (38%), Positives = 44/67 (65%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + L+ DD A++K +G ++ TD+C ++L +G +PG+HFYSLN +V+A
Sbjct: 209 CGAEIPRWIRLRLQSYGDDIASIKAFGEEVVTDLCDQLLTAG-APGLHFYSLNQADAVLA 267
Query: 195 VVDQLGL 215
+ D L L
Sbjct: 268 IADNLDL 274
[203][TOP]
>UniRef100_Q2STU2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis E264 RepID=Q2STU2_BURTA
Length = 276
Score = 57.8 bits (138), Expect = 6e-07
Identities = 26/67 (38%), Positives = 43/67 (64%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN + A
Sbjct: 211 CGAEVPRWIARRLESFGDDKDSIRAFGADVVTGLCRRLIDAGV-PGLHFYTLNGAAATKA 269
Query: 195 VVDQLGL 215
V ++LGL
Sbjct: 270 VCERLGL 276
[204][TOP]
>UniRef100_B1XSH7 Methylenetetrahydrofolate reductase n=1 Tax=Polynucleobacter
necessarius subsp. necessarius STIR1 RepID=B1XSH7_POLNS
Length = 276
Score = 57.8 bits (138), Expect = 6e-07
Identities = 26/67 (38%), Positives = 44/67 (65%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + L+ DD A+++ +G ++ TD+C ++L +G +PGIHFYSLN +V+A
Sbjct: 209 CGAEIPRWIRLRLQSYGDDIASIRAFGEEVVTDLCDQLLTAG-APGIHFYSLNQADAVLA 267
Query: 195 VVDQLGL 215
+ D L L
Sbjct: 268 IADNLDL 274
[205][TOP]
>UniRef100_B4X3B0 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax sp. DG881
RepID=B4X3B0_9GAMM
Length = 275
Score = 57.4 bits (137), Expect = 7e-07
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C VP + + L I+DDD AVK +G ++ T +C R+L G +PG+HFY++N +
Sbjct: 210 CGADVPRWLQSKLNDIKDDDVAVKAFGEEVVTRLCERLLAMG-APGLHFYTMNQAGPNLR 268
Query: 195 VVDQLGL 215
++D LG+
Sbjct: 269 ILDNLGM 275
[206][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 57.0 bits (136), Expect = 1e-06
Identities = 29/56 (51%), Positives = 40/56 (71%)
Frame = +3
Query: 3 MTGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSL 170
MTGFCKT+V AALEPI+D++ AV YGI + T+MC+++L +G+ I F SL
Sbjct: 12 MTGFCKTKVT----AALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK--ISFVSL 61
[207][TOP]
>UniRef100_UPI00016A8C43 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei DM98 RepID=UPI00016A8C43
Length = 276
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAGV-PGLHFYTLNGAAATKT 269
Query: 195 VVDQLGL 215
V ++LGL
Sbjct: 270 VCERLGL 276
[208][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 56.6 bits (135), Expect = 1e-06
Identities = 27/68 (39%), Positives = 42/68 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P L+ + DD AV YGI+ AT+ C +L+ G+ PG+HFY+LN +S +
Sbjct: 229 CGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGV-PGLHFYTLNKARSTVQ 287
Query: 195 VVDQLGLV 218
+V LGL+
Sbjct: 288 IVRNLGLL 295
[209][TOP]
>UniRef100_C4KXI8 Methylenetetrahydrofolate reductase n=23 Tax=pseudomallei group
RepID=C4KXI8_BURPS
Length = 276
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAGV-PGLHFYTLNGAAATKT 269
Query: 195 VVDQLGL 215
V ++LGL
Sbjct: 270 VCERLGL 276
[210][TOP]
>UniRef100_UPI00016A5F77 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
oklahomensis EO147 RepID=UPI00016A5F77
Length = 276
Score = 56.2 bits (134), Expect = 2e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAGV-PGLHFYTLNGAAATKI 269
Query: 195 VVDQLGL 215
V ++LGL
Sbjct: 270 VCERLGL 276
[211][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 56.2 bits (134), Expect = 2e-06
Identities = 27/67 (40%), Positives = 43/67 (64%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P V LE DD A+++++G ++ T +C R+L +G +PGIHFY+LN + +A
Sbjct: 216 CGAEIPRWVRKQLEAYGDDSASIRKFGEEVVTRLCERLLAAG-APGIHFYTLNQAEPSLA 274
Query: 195 VVDQLGL 215
V D L L
Sbjct: 275 VWDNLNL 281
[212][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 56.2 bits (134), Expect = 2e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD A++ +G+ + TD+C R+L++G+ PG+HFY+LN + A
Sbjct: 211 CGAEVPRWVAKRLESFGDDKEAIRAFGLDVVTDLCTRLLEAGV-PGLHFYTLNAAGATKA 269
Query: 195 VVDQLGL 215
+ +L L
Sbjct: 270 IWQRLKL 276
[213][TOP]
>UniRef100_C6W9J0 Methylenetetrahydrofolate reductase n=1 Tax=Actinosynnema mirum DSM
43827 RepID=C6W9J0_ACTMD
Length = 296
Score = 56.2 bits (134), Expect = 2e-06
Identities = 29/65 (44%), Positives = 39/65 (60%)
Frame = +3
Query: 27 VPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQ 206
VP SV AL+P D A + G+++ T M R+L G+ PG+HFY+LN K+ VV
Sbjct: 228 VPDSVARALDPFTGDAAGFRRAGVELVTRMGERLLAEGV-PGLHFYTLNRSKATREVVAD 286
Query: 207 LGLVP 221
LGL P
Sbjct: 287 LGLAP 291
[214][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P V LE DD +++ +G ++ T+MC R+L G +PG+HFYS+NL +A
Sbjct: 214 CGAEIPRWVRKQLEAYGDDADSIRAFGEQVITEMCERLLQGG-APGLHFYSMNLAGPSLA 272
Query: 195 VVDQLGL 215
+ + LGL
Sbjct: 273 IWNNLGL 279
[215][TOP]
>UniRef100_A0LTK4 Methylenetetrahydrofolate reductase n=1 Tax=Acidothermus
cellulolyticus 11B RepID=A0LTK4_ACIC1
Length = 331
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/64 (40%), Positives = 40/64 (62%)
Frame = +3
Query: 24 QVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVD 203
+ PP + + + D AAV+ GI++AT+MCRR+LD G +PG+HFY+LN + +
Sbjct: 239 EFPPELADRILAVADQPAAVRAIGIEVATEMCRRLLDEG-APGLHFYTLNRSTATREIYQ 297
Query: 204 QLGL 215
L L
Sbjct: 298 NLRL 301
[216][TOP]
>UniRef100_UPI00016AF3CB 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis MSMB43 RepID=UPI00016AF3CB
Length = 276
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/67 (37%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWIARRLESFGDDKDSIRAFGADVVTGLCRRLVDAGV-PGLHFYTLNGAAATKI 269
Query: 195 VVDQLGL 215
V ++LGL
Sbjct: 270 VCERLGL 276
[217][TOP]
>UniRef100_UPI00016A554F 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
ubonensis Bu RepID=UPI00016A554F
Length = 276
Score = 55.5 bits (132), Expect = 3e-06
Identities = 24/67 (35%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD A++ +G + T +C+R+LD+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWIARRLESFGDDRDAIRAFGADVVTGLCQRLLDAGV-PGLHFYTLNSAAATKT 269
Query: 195 VVDQLGL 215
+ ++LG+
Sbjct: 270 ICERLGV 276
[218][TOP]
>UniRef100_Q2Y5Z3 Methylenetetrahydrofolate reductase n=1 Tax=Nitrosospira
multiformis ATCC 25196 RepID=Q2Y5Z3_NITMU
Length = 281
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/67 (37%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + LE DD A+++ +G+ + TD+C R+L++G +PG+HFY+LN
Sbjct: 216 CGAEIPRWIRKRLEGYGDDTASIRAFGLDVVTDLCARLLNAG-APGLHFYTLNSAGLTTT 274
Query: 195 VVDQLGL 215
V +LGL
Sbjct: 275 VWQRLGL 281
[219][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 55.5 bits (132), Expect = 3e-06
Identities = 31/83 (37%), Positives = 43/83 (51%)
Frame = +3
Query: 6 TGFCKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKS 185
T C +PP + AA+E R+D + ++ G+ AT C +L G +PGIHFY+LN S
Sbjct: 226 TAMCGAAIPPRLRAAMEVRREDPDSARDLGVAYATLQCAELLRGG-APGIHFYTLNRSTS 284
Query: 186 VMAVVDQLGLVPQTQSIRSLPWR 254
A+V L S PWR
Sbjct: 285 TRAIVAALR--------ASEPWR 299
[220][TOP]
>UniRef100_A1WXM6 Methylenetetrahydrofolate reductase n=1 Tax=Halorhodospira
halophila SL1 RepID=A1WXM6_HALHL
Length = 304
Score = 55.5 bits (132), Expect = 3e-06
Identities = 29/71 (40%), Positives = 41/71 (57%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
CK +P + +E +DD + EYGI + T +C +LD+G +PGIHFY+LN V
Sbjct: 219 CKADMPRWLAQRMEAWKDDPQSRMEYGIDVVTRLCEDLLDNG-APGIHFYALNKAPVVER 277
Query: 195 VVDQLGLVPQT 227
+ LGL QT
Sbjct: 278 IWHNLGLSEQT 288
[221][TOP]
>UniRef100_C5CM27 Methylenetetrahydrofolate reductase n=1 Tax=Variovorax paradoxus
S110 RepID=C5CM27_VARPS
Length = 274
Score = 55.1 bits (131), Expect = 4e-06
Identities = 23/66 (34%), Positives = 42/66 (63%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + L+ DD A++K +G+ + TD+C R L G +P +HFY++N + +A
Sbjct: 210 CGAEIPRWIRLRLQGFGDDTASIKAFGLDVVTDLCAR-LQGGGAPALHFYTMNQSAATLA 268
Query: 195 VVDQLG 212
V+++LG
Sbjct: 269 VLERLG 274
[222][TOP]
>UniRef100_A0K3F1 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia
cenocepacia RepID=A0K3F1_BURCH
Length = 276
Score = 55.1 bits (131), Expect = 4e-06
Identities = 23/67 (34%), Positives = 43/67 (64%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T++C+R++D+G+ PG+HFY+LNL +
Sbjct: 211 CGAEVPRWVARRLESFGDDRESIRAFGADVVTNLCQRLIDAGV-PGLHFYTLNLATATRT 269
Query: 195 VVDQLGL 215
+ ++L +
Sbjct: 270 ICERLAV 276
[223][TOP]
>UniRef100_C4RLK6 Methylenetetrahydrofolate reductase n=1 Tax=Micromonospora sp. ATCC
39149 RepID=C4RLK6_9ACTO
Length = 305
Score = 55.1 bits (131), Expect = 4e-06
Identities = 27/60 (45%), Positives = 37/60 (61%)
Frame = +3
Query: 30 PPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMAVVDQL 209
PP++ A + DD AV+ GI+ A +MCRR+LD G+ PGIHF +LN + V QL
Sbjct: 241 PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGV-PGIHFITLNRSTATREVWQQL 299
[224][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 55.1 bits (131), Expect = 4e-06
Identities = 23/67 (34%), Positives = 41/67 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + LE DD +++ +GI + T +C+ +L+SG +PGIHFY++N + +
Sbjct: 213 CGAEIPRWISKRLEGFADDQDSIRAFGIDVVTQLCQTLLESG-APGIHFYTMNQTQPTLQ 271
Query: 195 VVDQLGL 215
+ LGL
Sbjct: 272 ICRNLGL 278
[225][TOP]
>UniRef100_B5WH86 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia sp. H160
RepID=B5WH86_9BURK
Length = 276
Score = 55.1 bits (131), Expect = 4e-06
Identities = 22/67 (32%), Positives = 45/67 (67%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G+++ T++C+R++D+ + PG+HFY+LN + A
Sbjct: 211 CGAEVPRWIARRLESFGDDRESIRAFGLEVVTNLCQRLVDAKV-PGLHFYTLNTAAATKA 269
Query: 195 VVDQLGL 215
+ ++LG+
Sbjct: 270 ICERLGV 276
[226][TOP]
>UniRef100_A4LN89 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei 305 RepID=A4LN89_BURPS
Length = 276
Score = 55.1 bits (131), Expect = 4e-06
Identities = 25/66 (37%), Positives = 41/66 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +CRR++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAGV-PGLHFYTLNGAAATKT 269
Query: 195 VVDQLG 212
V ++LG
Sbjct: 270 VCERLG 275
[227][TOP]
>UniRef100_Q13T38 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia xenovorans
LB400 RepID=Q13T38_BURXL
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 23/67 (34%), Positives = 43/67 (64%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G+ + TD+CRR++D+ + PG+HFY+LN + A
Sbjct: 211 CGAEVPRWIARRLESFGDDRESIRAFGLDVVTDLCRRLIDAKV-PGLHFYTLNGAAATKA 269
Query: 195 VVDQLGL 215
+ ++L +
Sbjct: 270 ICERLNV 276
[228][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 26/67 (38%), Positives = 40/67 (59%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G+ + T MC R+L G +PG+HFY+LN S A
Sbjct: 211 CGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGG-APGLHFYTLNAAGSTRA 269
Query: 195 VVDQLGL 215
+ +LGL
Sbjct: 270 IWQRLGL 276
[229][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 26/67 (38%), Positives = 40/67 (59%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP + LE DD +++ +G+ + T MC R+L G +PG+HFY+LN S A
Sbjct: 211 CGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGG-APGLHFYTLNAAGSTRA 269
Query: 195 VVDQLGL 215
+ +LGL
Sbjct: 270 IWQRLGL 276
[230][TOP]
>UniRef100_B1JTJ6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia MC0-3 RepID=B1JTJ6_BURCC
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 23/67 (34%), Positives = 42/67 (62%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +C+R++D+G+ PG+HFY+LNL +
Sbjct: 211 CGAEVPRWVARRLESFGDDRESIRAFGADVVTSLCQRLIDAGV-PGLHFYTLNLATATRT 269
Query: 195 VVDQLGL 215
+ ++L +
Sbjct: 270 ICERLAV 276
[231][TOP]
>UniRef100_B1TB42 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia ambifaria
MEX-5 RepID=B1TB42_9BURK
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 24/67 (35%), Positives = 41/67 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD A++ +G + T +C+R++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDRDAIRAFGADVVTSLCQRLVDAGV-PGLHFYTLNAASATRT 269
Query: 195 VVDQLGL 215
+ ++L L
Sbjct: 270 ICERLAL 276
[232][TOP]
>UniRef100_A2W5Y4 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia dolosa
AUO158 RepID=A2W5Y4_9BURK
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 24/65 (36%), Positives = 40/65 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G + T +CRR+LD+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDRESIRAFGADVVTSLCRRLLDAGV-PGLHFYTLNAAAATRT 269
Query: 195 VVDQL 209
+ ++L
Sbjct: 270 ICERL 274
[233][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 54.3 bits (129), Expect = 6e-06
Identities = 22/69 (31%), Positives = 44/69 (63%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + ALE DD+ +++ +G+ + T++C +L++ +PG+HFY++N +
Sbjct: 213 CGAEIPRWLRKALENYGDDEESLRAFGVDLVTELCEVLLENE-APGLHFYTMNQTEPTAQ 271
Query: 195 VVDQLGLVP 221
+V LGL+P
Sbjct: 272 IVRNLGLIP 280
[234][TOP]
>UniRef100_B2JIP2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia phymatum
STM815 RepID=B2JIP2_BURP8
Length = 276
Score = 54.3 bits (129), Expect = 6e-06
Identities = 24/67 (35%), Positives = 44/67 (65%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD +++ +G+ + T++CRR++D+ + PG+HFY+LN + A
Sbjct: 211 CGAEVPRWVARRLESFGDDRESIRAFGLDVVTNLCRRLVDAKV-PGLHFYTLNGAAASKA 269
Query: 195 VVDQLGL 215
+ ++LG+
Sbjct: 270 ICERLGV 276
[235][TOP]
>UniRef100_C6NUC2 Methylenetetrahydrofolate reductase n=1 Tax=Acidithiobacillus
caldus ATCC 51756 RepID=C6NUC2_9GAMM
Length = 276
Score = 54.3 bits (129), Expect = 6e-06
Identities = 25/67 (37%), Positives = 40/67 (59%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C ++P + +E DD A E I++A+ CR +LD G +PG+HFY+LN ++ +A
Sbjct: 211 CGAEIPQFLRRRMESFADDPGAQAELAIEVASRQCRLLLDQG-APGLHFYTLNQAEATLA 269
Query: 195 VVDQLGL 215
+ LGL
Sbjct: 270 IARNLGL 276
[236][TOP]
>UniRef100_Q0BJC4 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia ambifaria
AMMD RepID=Q0BJC4_BURCM
Length = 276
Score = 53.9 bits (128), Expect = 8e-06
Identities = 23/67 (34%), Positives = 41/67 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD A++ +G + T +C+R++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDRDAIRAFGADVVTSLCQRLVDAGV-PGLHFYTLNTASATRT 269
Query: 195 VVDQLGL 215
+ ++L +
Sbjct: 270 ICERLAM 276
[237][TOP]
>UniRef100_B1YR55 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia ambifaria
RepID=B1YR55_BURA4
Length = 276
Score = 53.9 bits (128), Expect = 8e-06
Identities = 23/67 (34%), Positives = 41/67 (61%)
Frame = +3
Query: 15 CKTQVPPSVDAALEPIRDDDAAVKEYGIKMATDMCRRILDSGLSPGIHFYSLNLEKSVMA 194
C +VP V LE DD A++ +G + T +C+R++D+G+ PG+HFY+LN +
Sbjct: 211 CGAEVPRWVARRLESFGDDRDAIRAFGADVVTSLCQRLVDAGV-PGLHFYTLNAASATRT 269
Query: 195 VVDQLGL 215
+ ++L +
Sbjct: 270 ICERLAM 276