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[1][TOP]
>UniRef100_B1XKP8 DNA topoisomerase n=1 Tax=Synechococcus sp. PCC 7002
RepID=B1XKP8_SYNP2
Length = 880
Score = 139 bits (351), Expect = 9e-32
Identities = 74/154 (48%), Positives = 98/154 (63%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLPD+ G+ L+ V+H T PPARYT+ASLVK LE+ G+GRPSTYA+I+ T+V RG
Sbjct: 457 VLPDLKEGDQPTCKKLEEVDHNTQPPARYTEASLVKALESKGIGRPSTYATIIGTIVDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV ++ +AL P TAF V LL +FP+ VD FT++ME++LD IA G A
Sbjct: 517 YV---------QIRDKALTPTFTAFAVTALLEEHFPNLVDTDFTSQMEQTLDEIATGKAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++YLG DGL V E+ ID A A+ +
Sbjct: 568 WLPYLKNFYLGDDGLGTQVKVREENIDPATAKAI 601
[2][TOP]
>UniRef100_Q2JJ84 DNA topoisomerase n=1 Tax=Synechococcus sp. JA-2-3B'a(2-13)
RepID=Q2JJ84_SYNJB
Length = 933
Score = 135 bits (340), Expect = 2e-30
Identities = 74/153 (48%), Positives = 97/153 (63%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+P+ L+ V H T PPARYT+ASLVK LE+ G+GRPSTYA+I+ T++ RGY
Sbjct: 464 LPLLRQGDPLRCQKLEPVAHETQPPARYTEASLVKVLESEGIGRPSTYATILNTIMSRGY 523
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R AL P TAF V +LL +YFP+ V+ FTAEME++LD IA+G A+
Sbjct: 524 V---------RPMGSALVPTYTAFAVTELLEKYFPNLVNTRFTAEMEQTLDDIASGQAEW 574
Query: 428 QEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++LG GL V E EID+ AR +
Sbjct: 575 LPYLRHFFLGEQGLEGQVKARELEIDSGLARSI 607
[3][TOP]
>UniRef100_Q2JWS9 DNA topoisomerase n=1 Tax=Synechococcus sp. JA-3-3Ab
RepID=Q2JWS9_SYNJA
Length = 886
Score = 135 bits (339), Expect = 2e-30
Identities = 74/153 (48%), Positives = 97/153 (63%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+P++ L+ V H T PP RYT+ASLVK LE+ G+GRPSTYA+I+ T++ RGY
Sbjct: 462 LPLLRQGDPLSCLQLEPVGHETQPPPRYTEASLVKVLESEGIGRPSTYATILNTIMSRGY 521
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R AL P TAF V +LL +YFP+ V+ FTAEME++LD IA+G AD
Sbjct: 522 V---------RSMGNALVPTYTAFAVTELLEKYFPNLVNTRFTAEMEQTLDDIASGQADW 572
Query: 428 QEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++LG GL V E EID+ AR +
Sbjct: 573 LPYLRHFFLGEQGLEGQVKARELEIDSGLARSI 605
[4][TOP]
>UniRef100_B8HP12 DNA topoisomerase n=1 Tax=Cyanothece sp. PCC 7425
RepID=B8HP12_CYAP4
Length = 910
Score = 134 bits (337), Expect = 4e-30
Identities = 70/152 (46%), Positives = 91/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + PG+ L+ + H T PPARYT+A+LVK LE+ G+GRPSTYASI+ T++ RG
Sbjct: 463 ILPPLQPGDTPTCRTLEAIAHETQPPARYTEATLVKTLESEGIGRPSTYASIISTIIDRG 522
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y R AL P TAF V +LL ++FP VD FTA ME++LD I+ G D
Sbjct: 523 YAYR---------QGNALVPTFTAFAVTRLLEKHFPDLVDVGFTARMEQTLDDISTGGVD 573
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG +GL V E +ID AR
Sbjct: 574 WLPYLRDFYLGENGLEHQVKEREVQIDPVEAR 605
[5][TOP]
>UniRef100_B4WLY1 DNA topoisomerase n=1 Tax=Synechococcus sp. PCC 7335
RepID=B4WLY1_9SYNE
Length = 910
Score = 132 bits (332), Expect = 1e-29
Identities = 70/152 (46%), Positives = 92/152 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPDV G+P+ ++L+ + H T PPARYT+ASLVK LE G+GRPSTYA+++ T+V R
Sbjct: 460 ILPDVKAGDPLDCASLEAIGHETQPPARYTEASLVKTLEKEGIGRPSTYATVISTIVARR 519
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L +L P TAF V +LL + FP VD FTA ME++LD I+ G A+
Sbjct: 520 Y---------AELIGNSLVPTFTAFAVTELLEKNFPDLVDVHFTANMEKTLDDISVGNAE 570
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G DGLA V + ID AR
Sbjct: 571 WLPYLKGFYGGDDGLAHQVEERQDNIDPTEAR 602
[6][TOP]
>UniRef100_B9YL16 DNA topoisomerase n=1 Tax='Nostoc azollae' 0708 RepID=B9YL16_ANAAZ
Length = 883
Score = 131 bits (329), Expect = 3e-29
Identities = 70/152 (46%), Positives = 92/152 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + L+ V+H T PPARYT+ASLVK LE+ G+GRPSTYASI+ T++ +G
Sbjct: 457 ILPPLKVGDHPTCTELEAVDHETQPPARYTEASLVKTLESEGIGRPSTYASIIGTIIDKG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L AL P TAF V LL ++FP VD +FT++ME++LD IA G A
Sbjct: 517 Y---------AHLVSNALIPTFTAFAVTDLLEKHFPDIVDPSFTSKMEQTLDDIATGEAK 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E +ID AR
Sbjct: 568 WLPYLKKFYLGEKGLETLVRERESQIDATTAR 599
[7][TOP]
>UniRef100_Q7VDE6 DNA topoisomerase n=1 Tax=Prochlorococcus marinus
RepID=Q7VDE6_PROMA
Length = 872
Score = 130 bits (328), Expect = 4e-29
Identities = 72/147 (48%), Positives = 91/147 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLP + G+ ++ ++D + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 438 VLPVLNVGDVLSPKSVDAMGHETKPPARYSEASLVKTLEKEGIGRPSTYASIIGTIVDRG 497
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y S L +LAP TAF V LL +FP VD FTA ME SLD I++G
Sbjct: 498 YAS---------LSANSLAPTFTAFAVTSLLEEHFPDLVDTTFTARMESSLDEISSGTVQ 548
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL S+Y G GLAA V + E +ID
Sbjct: 549 WLPYLESFYKGRKGLAAQVDKREGDID 575
[8][TOP]
>UniRef100_Q11AC4 DNA topoisomerase n=1 Tax=Trichodesmium erythraeum IMS101
RepID=Q11AC4_TRIEI
Length = 874
Score = 130 bits (328), Expect = 4e-29
Identities = 68/153 (44%), Positives = 92/153 (60%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ A + +++V H T PPAR+T+ASLVK LE+ G+GRPSTYA+++ T+V RGY
Sbjct: 458 LPAIKQGDHPACTEIEVVGHETQPPARFTEASLVKTLESEGIGRPSTYATVIGTIVDRGY 517
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
+L AL P TAF V LL ++FP FVD FTA ME++LD I+ G A
Sbjct: 518 A---------KLQSNALVPTFTAFAVTTLLEKHFPEFVDVKFTARMEQTLDDISMGEAQW 568
Query: 428 QEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL + E +ID AR +
Sbjct: 569 VPYLKKFYFGESGLDTQIKEQENQIDPKLARTI 601
[9][TOP]
>UniRef100_B2IWS5 DNA topoisomerase n=1 Tax=Nostoc punctiforme PCC 73102
RepID=B2IWS5_NOSP7
Length = 886
Score = 129 bits (324), Expect = 1e-28
Identities = 70/152 (46%), Positives = 92/152 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G+ + L+ V H T PPARYT+ASLVK LE+ G+GRPSTYASI+ T++ +G
Sbjct: 457 ILPNLKVGDHPNCTDLEAVGHETQPPARYTEASLVKTLESEGIGRPSTYASIIGTIIDKG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L AL P TAF V LL ++FP VD +FT++ME++LD IA G A
Sbjct: 517 YA---------HLVSNALIPTFTAFAVTDLLEKHFPDIVDPSFTSKMEQTLDDIATGEAK 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E +ID AR
Sbjct: 568 WLPYLQKFYLGEKGLETLVKERESQIDATTAR 599
[10][TOP]
>UniRef100_B5W1H4 DNA topoisomerase n=1 Tax=Arthrospira maxima CS-328
RepID=B5W1H4_SPIMA
Length = 911
Score = 129 bits (323), Expect = 2e-28
Identities = 70/153 (45%), Positives = 90/153 (58%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ L+ V H T PPAR+T+ASLVK LE+ GVGRPSTYAS++ T++ RGY
Sbjct: 458 LPPLKVGQHPDCKDLEAVGHETQPPARFTEASLVKTLESEGVGRPSTYASVIGTIIDRGY 517
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
++ AL P TAF V+ LL ++FP VD FTA ME +LD IA G AD+
Sbjct: 518 A---------QIKGNALIPTFTAFAVNSLLEKHFPDLVDIRFTARMENTLDEIATGQADQ 568
Query: 428 QEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL V E +ID AR +
Sbjct: 569 LPYLQQFYSGDGGLENQVKEQESQIDAKVARTI 601
[11][TOP]
>UniRef100_A0YII1 DNA topoisomerase n=1 Tax=Lyngbya sp. PCC 8106 RepID=A0YII1_9CYAN
Length = 893
Score = 129 bits (323), Expect = 2e-28
Identities = 71/154 (46%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ L+ V H T PPAR+T+ASLVK LE+ GVGRPSTYAS++ T++ RG
Sbjct: 457 LLPPLKEGDHPNCQELEAVSHETQPPARFTEASLVKTLESEGVGRPSTYASVIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV +L AL P TAF V LL ++FP VD FTA ME +LD IAAG A
Sbjct: 517 YV---------QLKGNALTPTFTAFAVTNLLEKHFPDLVDIGFTARMENTLDDIAAGEAS 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL V E +I+ AR +
Sbjct: 568 WLPYLQKFYSGEAGLDTQVREQESQIEAKVARTI 601
[12][TOP]
>UniRef100_A0LWD4 DNA topoisomerase n=1 Tax=Acidothermus cellulolyticus 11B
RepID=A0LWD4_ACIC1
Length = 898
Score = 128 bits (322), Expect = 2e-28
Identities = 72/148 (48%), Positives = 94/148 (63%), Gaps = 1/148 (0%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
+ + LPD+ GE V V+AL EHTTTPP RYT+ASL++ LE G+GRPST+ASIV T++
Sbjct: 490 SGRTLPDLTEGETVPVAALTPAEHTTTPPPRYTEASLIRALEERGIGRPSTFASIVSTII 549
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
R YV RG QAL P AF V +LL ++F + VD FTAEME +LD IA
Sbjct: 550 ERDYVFKRG----------QALVPTFLAFAVVRLLEKHFGNLVDYDFTAEMEENLDRIAN 599
Query: 413 GAADRQEYLSSYYLGSDGLAASVARMEK 496
G A R E+L+ +Y GS S A +++
Sbjct: 600 GEAHRLEWLTRFYFGSPTDGGSAAGLKQ 627
[13][TOP]
>UniRef100_A0ZI69 DNA topoisomerase n=1 Tax=Nodularia spumigena CCY9414
RepID=A0ZI69_NODSP
Length = 890
Score = 128 bits (321), Expect = 3e-28
Identities = 69/152 (45%), Positives = 93/152 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + L+ V H T PPARYT+A+LVK LE+ G+GRPSTYASI+ T++ +G
Sbjct: 457 ILPSLKVGDHPNCTDLEAVGHETQPPARYTEATLVKTLESEGIGRPSTYASIIGTIIDKG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y +L AL P TAF V LL ++FP VD +FT++ME++LD IA G A
Sbjct: 517 YA---------QLVSNALIPTFTAFAVTNLLEKHFPDVVDPSFTSKMEQTLDDIATGEAK 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E +ID + AR
Sbjct: 568 WLPYLREFYLGDKGLETLVKEQESQIDASQAR 599
[14][TOP]
>UniRef100_B0CFN9 DNA topoisomerase n=1 Tax=Acaryochloris marina MBIC11017
RepID=B0CFN9_ACAM1
Length = 892
Score = 127 bits (319), Expect = 5e-28
Identities = 68/154 (44%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + L + H T PPAR+T+ASLVK LE G+GRPSTYAS++ T++ RG
Sbjct: 457 LLPSLKQGDTPECTELSPIGHETQPPARFTEASLVKMLEKEGIGRPSTYASVIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y R AL P TAF V LL ++FP VD +FTA MER LD I+ G +
Sbjct: 517 YAQRQAN---------ALVPTFTAFAVTALLEQHFPDLVDLSFTARMERRLDGISTGEVE 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YLS +YLG +GL V + +ID AR +
Sbjct: 568 WLPYLSDFYLGDEGLETLVKTRQDQIDPGEARTI 601
[15][TOP]
>UniRef100_B7KFB6 DNA topoisomerase n=1 Tax=Cyanothece sp. PCC 7424
RepID=B7KFB6_CYAP7
Length = 872
Score = 127 bits (318), Expect = 6e-28
Identities = 72/152 (47%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE GVGRPSTYASI+ T+V RG
Sbjct: 457 ILPPLKEGDHPDCKQLDVLGHETQPPARYTEASLVKTLETEGVGRPSTYASIIGTIVERG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y +L +AL P TAF V LL +FP V+ FT++ME++LD IA G A
Sbjct: 517 Y---------AQLRNKALIPTFTAFAVVSLLENHFPDLVNTGFTSKMEQTLDDIATGEAK 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E EI+ AR
Sbjct: 568 WLPYLQKFYLGDKGLENQVKLRENEIEPGEAR 599
[16][TOP]
>UniRef100_Q3MH80 DNA topoisomerase n=1 Tax=Anabaena variabilis ATCC 29413
RepID=Q3MH80_ANAVT
Length = 881
Score = 126 bits (317), Expect = 8e-28
Identities = 68/152 (44%), Positives = 91/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ V H T PPARYT+A+LVK LE+ G+GRPSTYASI+ T++ +G
Sbjct: 457 ILPSLKVGDHPDCKNIEAVGHETQPPARYTEATLVKTLESEGIGRPSTYASIIGTIIDKG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y +L AL P TAF V LL ++FP VD +FT++ME++LD IA G A
Sbjct: 517 Y---------SQLVNNALIPTFTAFAVTDLLEKHFPDIVDPSFTSKMEQTLDDIAEGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E +ID AR
Sbjct: 568 WLPYLKKFYLGDQGLETLVRERESQIDAGKAR 599
[17][TOP]
>UniRef100_Q8DHR4 DNA topoisomerase n=1 Tax=Thermosynechococcus elongatus BP-1
RepID=Q8DHR4_THEEB
Length = 887
Score = 126 bits (316), Expect = 1e-27
Identities = 71/155 (45%), Positives = 91/155 (58%), Gaps = 1/155 (0%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + AL+ V H T PP RYT+ASLVK LE G+GRPSTYA+I+ T+ R
Sbjct: 457 MLPVMQVGDILRCQALESVRHETQPPPRYTEASLVKALEQAGIGRPSTYATIISTIQDRE 516
Query: 245 Y-VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
Y + RG AL P TAF V LL +YFP VD FTA ME++LD I+ G
Sbjct: 517 YAIRRGN----------ALEPTFTAFAVTALLEKYFPDLVDINFTARMEQTLDDISTGEV 566
Query: 422 DRQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
Q YL S+YLG +GL V E+ I+ AR +
Sbjct: 567 QWQPYLESFYLGENGLEQQVKERERTIEATEARAI 601
[18][TOP]
>UniRef100_B4VNQ8 DNA topoisomerase n=1 Tax=Microcoleus chthonoplastes PCC 7420
RepID=B4VNQ8_9CYAN
Length = 877
Score = 126 bits (316), Expect = 1e-27
Identities = 67/154 (43%), Positives = 91/154 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLP + G+ L+ + H T PP RYT+ASLVK LE+ G+GRPSTYASI+ T++ RG
Sbjct: 457 VLPALAVGDHPECKNLEAIGHETQPPGRYTEASLVKTLESEGIGRPSTYASIIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ + L P TAF V LL ++FP VD +FTA+ME++LD I+ G A+
Sbjct: 517 Y---------AQMQKKTLIPTFTAFAVTSLLEKHFPDLVDTSFTAKMEQTLDEISTGEAE 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL V E +ID AR +
Sbjct: 568 WLPYLEKFYRGDKGLETQVREREDQIDPNEARSI 601
[19][TOP]
>UniRef100_B4B237 DNA topoisomerase n=1 Tax=Cyanothece sp. PCC 7822
RepID=B4B237_9CHRO
Length = 879
Score = 126 bits (316), Expect = 1e-27
Identities = 70/152 (46%), Positives = 93/152 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + LD + H T PPARYT+ASLVK LE+ GVGRPSTYASI+ T+V RG
Sbjct: 457 ILPPLKVGDHPSCKQLDALGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIVERG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ + L P TAF V LL ++FP V+ FT++ME++LD IA+G A
Sbjct: 517 Y---------AQMRNKTLVPTFTAFAVVSLLEQHFPDLVNTGFTSKMEQTLDDIASGEAK 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E EID + A+
Sbjct: 568 WLPYLQKFYLGEHGLENQVKLREHEIDPSNAK 599
[20][TOP]
>UniRef100_B7JYQ6 DNA topoisomerase n=1 Tax=Cyanothece sp. PCC 8801
RepID=B7JYQ6_CYAP8
Length = 877
Score = 125 bits (315), Expect = 1e-27
Identities = 69/152 (45%), Positives = 92/152 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE+ GVGRPSTYASI+ T++ RG
Sbjct: 457 ILPPLQEGDHPNCQQLDVLGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ +AL P TAF V LL +FP VD FT++ME++LD IA G A
Sbjct: 517 Y---------AQMRSKALVPTFTAFAVVSLLEGHFPDLVDTKFTSKMEQTLDEIATGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL ++YLG GL V ++ID A+
Sbjct: 568 WLPYLKNFYLGDKGLDTQVKVKTEQIDPGVAK 599
[21][TOP]
>UniRef100_C7QKW5 DNA topoisomerase I n=1 Tax=Cyanothece sp. PCC 8802
RepID=C7QKW5_CYAP0
Length = 877
Score = 125 bits (315), Expect = 1e-27
Identities = 69/152 (45%), Positives = 92/152 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE+ GVGRPSTYASI+ T++ RG
Sbjct: 457 ILPPLQEGDHPNCQQLDVLGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ +AL P TAF V LL +FP VD FT++ME++LD IA G A
Sbjct: 517 Y---------AQMRSKALVPTFTAFAVVSLLEGHFPDLVDTKFTSKMEQTLDEIATGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL ++YLG GL V ++ID A+
Sbjct: 568 WLPYLKNFYLGDKGLDTQVKVKTEQIDPGVAK 599
[22][TOP]
>UniRef100_Q0S8J3 DNA topoisomerase n=1 Tax=Rhodococcus jostii RHA1
RepID=Q0S8J3_RHOSR
Length = 973
Score = 125 bits (313), Expect = 2e-27
Identities = 76/151 (50%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP +V G+ V + LD HTT PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 477 GQSDDAESRLPVLVEGQAVTATKLDPDGHTTNPPARYTEASLIKTLEELGIGRPSTYSSI 536
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T++ RGYV RG+ AL P AF V LL +F VD FTA ME L
Sbjct: 537 IKTILDRGYVYKRGS----------ALVPSWVAFAVIGLLEMHFGRLVDFDFTAGMEDDL 586
Query: 398 DAIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
DAIA G R +LSS+Y G D G SVAR
Sbjct: 587 DAIAGGREQRGNWLSSFYFGGDHGAEGSVAR 617
[23][TOP]
>UniRef100_C1BA07 DNA topoisomerase n=1 Tax=Rhodococcus opacus B4 RepID=C1BA07_RHOOB
Length = 973
Score = 125 bits (313), Expect = 2e-27
Identities = 76/151 (50%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP +V G+ V + LD HTT PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 477 GQSDDAESRLPVLVEGQAVTATKLDPDGHTTNPPARYTEASLIKTLEELGIGRPSTYSSI 536
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T++ RGYV RG+ AL P AF V LL +F VD FTA ME L
Sbjct: 537 IKTILDRGYVYKRGS----------ALVPSWVAFAVIGLLEMHFGRLVDFDFTAGMEDDL 586
Query: 398 DAIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
DAIA G R +LSS+Y G D G SVAR
Sbjct: 587 DAIAGGREQRGNWLSSFYFGGDHGAEGSVAR 617
[24][TOP]
>UniRef100_P34185 DNA topoisomerase 1 n=2 Tax=Synechococcus elongatus
RepID=TOP1_SYNE7
Length = 883
Score = 125 bits (313), Expect = 2e-27
Identities = 72/152 (47%), Positives = 88/152 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ L + H T PPARYT+ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 457 LLPALKVGDRPTCQELAAIGHETQPPARYTEASLVKMLENEGIGRPSTYASIIGTIVDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y +L L P TAF V LL ++FP VD +F+A ME+SLD I+ G D
Sbjct: 517 YA---------QLVSNTLTPTFTAFAVTALLEQHFPDLVDTSFSARMEQSLDDISNGEVD 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YLS +Y G GL V E EID A AR
Sbjct: 568 WLPYLSQFYRGDRGLEEQVKLRESEIDPAAAR 599
[25][TOP]
>UniRef100_P73810 DNA topoisomerase 1 n=1 Tax=Synechocystis sp. PCC 6803
RepID=TOP1_SYNY3
Length = 898
Score = 124 bits (312), Expect = 3e-27
Identities = 69/154 (44%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ +D V H T PPARYT+ASLVK LE+ GVGRPSTYASI+ T++ RG
Sbjct: 457 ILPPLKVGDRPNCREIDTVGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV ++ +AL P TAF V LL +FP VD FT+ ME+ LD IA G
Sbjct: 517 YV---------QMRSKALTPTFTAFAVVSLLESHFPDLVDTGFTSRMEQKLDEIAIGKTQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++LG GL V + +ID A A+ +
Sbjct: 568 WLPYLQGFFLGESGLENQVKVRQDQIDPAIAKAI 601
[26][TOP]
>UniRef100_A6W588 DNA topoisomerase n=1 Tax=Kineococcus radiotolerans SRS30216
RepID=A6W588_KINRD
Length = 963
Score = 124 bits (310), Expect = 5e-27
Identities = 67/136 (49%), Positives = 85/136 (62%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP VV G+P+ S L H T+PPARYT+ASLVK LE G+GRPST+ASI+ T+V RGY
Sbjct: 486 LPQVVAGDPLTASDLATAGHETSPPARYTEASLVKALEEKGIGRPSTFASIISTIVDRGY 545
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V+ AL P AF V +LL +FP VD FTA ME LDAI+ G A+R
Sbjct: 546 VT---------YKGSALVPSWLAFAVTRLLEEHFPKLVDYDFTAGMENDLDAISRGEAER 596
Query: 428 QEYLSSYYLGSDGLAA 475
++L+ +Y G+ G A
Sbjct: 597 VDWLTRFYFGAAGPTA 612
[27][TOP]
>UniRef100_Q7V2N7 DNA topoisomerase n=1 Tax=Prochlorococcus marinus subsp. pastoris
str. CCMP1986 RepID=Q7V2N7_PROMP
Length = 870
Score = 123 bits (309), Expect = 7e-27
Identities = 65/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPD+ G + V + + H T PARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPDLTQGSVLEVDSKEATYHETKSPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + +L+P TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNSLSPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[28][TOP]
>UniRef100_B5INS2 DNA topoisomerase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5INS2_9CHRO
Length = 912
Score = 123 bits (309), Expect = 7e-27
Identities = 66/152 (43%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ A ++ + H T PPARY++A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 463 LLPSLAVGDAPACRGVEALGHQTQPPARYSEAALVKMLEKEGIGRPSTYASIIGTIVDRG 522
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD FTA ME++LD I+ G +
Sbjct: 523 YAT---------LQNNSLTPSFTAFAVTALLEEHFPDLVDTGFTARMEQTLDEISHGQVE 573
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL ++Y G +GL V R E +ID +R
Sbjct: 574 WLPYLETFYKGEEGLETQVLRREGDIDPGVSR 605
[29][TOP]
>UniRef100_A8G3F0 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9215
RepID=A8G3F0_PROM2
Length = 868
Score = 123 bits (308), Expect = 9e-27
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V+ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTTGTCLEVTNKESTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[30][TOP]
>UniRef100_A3PBF8 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9301
RepID=A3PBF8_PROM0
Length = 868
Score = 123 bits (308), Expect = 9e-27
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V+ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTTGTCLDVTKKESTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[31][TOP]
>UniRef100_A2BPR8 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. AS9601
RepID=A2BPR8_PROMS
Length = 868
Score = 123 bits (308), Expect = 9e-27
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V++ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTTGTCLEVTSKESTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E ID
Sbjct: 569 WLPYLETFYKGKNGLEIKVQKTEGNID 595
[32][TOP]
>UniRef100_Q1PJN8 DNA topoisomerase n=1 Tax=uncultured Prochlorococcus marinus clone
HOT0M-10D2 RepID=Q1PJN8_PROMA
Length = 726
Score = 123 bits (308), Expect = 9e-27
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V+ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 316 ILPNLTTGTCLEVTNKESTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 375
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 376 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 426
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 427 WLPYLETFYKGKNGLEVKVQKTEGDID 453
[33][TOP]
>UniRef100_B9P0I6 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9202
RepID=B9P0I6_PROMA
Length = 868
Score = 123 bits (308), Expect = 9e-27
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V+ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTTGTCLEVTNKESTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[34][TOP]
>UniRef100_Q31C99 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9312
RepID=Q31C99_PROM9
Length = 868
Score = 122 bits (307), Expect = 1e-26
Identities = 66/147 (44%), Positives = 89/147 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V+ + H T PPARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTTGTCLEVTDKEPTFHETKPPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + LAP TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNTLAPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[35][TOP]
>UniRef100_A9BE54 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9211
RepID=A9BE54_PROM4
Length = 899
Score = 122 bits (306), Expect = 2e-26
Identities = 67/154 (43%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ V ++ + H T PPARY++ASLVK LE G+GRPSTY+SI+ T+V RG
Sbjct: 458 LLPSLEVGDTPIVEKIEPLAHQTQPPARYSEASLVKMLEKEGIGRPSTYSSIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y S + +L P TAF V LL +FP VD FTA ME +LD I+ G +
Sbjct: 518 YSS---------IHNNSLIPSFTAFAVTALLEEHFPDLVDTRFTARMELTLDEISTGKVE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YLS +Y G DGL V + E +ID +R +
Sbjct: 569 WLPYLSGFYKGEDGLENQVEKKEGDIDPGLSRTI 602
[36][TOP]
>UniRef100_Q8YTE2 DNA topoisomerase n=1 Tax=Nostoc sp. PCC 7120 RepID=Q8YTE2_ANASP
Length = 881
Score = 122 bits (305), Expect = 2e-26
Identities = 67/152 (44%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ V H T PPARYT+A+LVK LE+ G+GRPSTYASI+ T++ +G
Sbjct: 457 ILPSLKVGDHPDCQNIEAVGHETQPPARYTEATLVKTLESEGIGRPSTYASIIGTIIDKG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y +L AL P TAF V LL + FP VD +FT++ME++LD IA G +
Sbjct: 517 Y---------SQLVNNALIPTFTAFAVTDLLEKNFPDIVDPSFTSKMEQTLDDIADGEVE 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +YLG GL V E ID + AR
Sbjct: 568 WLPYLKKFYLGDKGLETLVRERESLIDASKAR 599
[37][TOP]
>UniRef100_B1WVJ8 DNA topoisomerase n=1 Tax=Cyanothece sp. ATCC 51142
RepID=B1WVJ8_CYAA5
Length = 881
Score = 122 bits (305), Expect = 2e-26
Identities = 68/154 (44%), Positives = 89/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE GVGRPSTYASI+ T+ RG
Sbjct: 457 ILPPLAEGDHPDCKELDVLGHETQPPARYTEASLVKMLEGEGVGRPSTYASIIGTIRDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ +AL P TAF V LL +FP VD FT++ME++LD IA G A
Sbjct: 517 Y---------AQMRSKALVPTFTAFAVVNLLENHFPDLVDTKFTSKMEQTLDEIATGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL V +ID A+ +
Sbjct: 568 WVPYLQKFYSGEEGLDTQVKVRVDQIDPGVAKAI 601
[38][TOP]
>UniRef100_A3Z624 DNA topoisomerase n=1 Tax=Synechococcus sp. RS9917
RepID=A3Z624_9SYNE
Length = 904
Score = 122 bits (305), Expect = 2e-26
Identities = 67/152 (44%), Positives = 87/152 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPALKSGDAPTPREVEALGHQTQPPARYSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y S L AL P TAF V LL +FP VD FTA ME +LD I+ G
Sbjct: 518 YAS---------LQNNALTPSFTAFAVTALLEEHFPDLVDTGFTARMESTLDEISTGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G +GL + V + E +ID +R
Sbjct: 569 WLPYLEGFYKGEEGLESQVQKREGDIDAGASR 600
[39][TOP]
>UniRef100_A3ILD7 DNA topoisomerase n=1 Tax=Cyanothece sp. CCY0110 RepID=A3ILD7_9CHRO
Length = 881
Score = 122 bits (305), Expect = 2e-26
Identities = 68/154 (44%), Positives = 89/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE GVGRPSTYASI+ T+ RG
Sbjct: 457 ILPPLTEGDHPDCKELDVLGHETQPPARYTEASLVKMLEGEGVGRPSTYASIIGTIRDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ +AL P TAF V LL +FP VD FT++ME++LD IA G A
Sbjct: 517 Y---------AQMRSKALVPTFTAFAVVNLLENHFPDLVDTKFTSKMEQTLDEIATGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL V +ID A+ +
Sbjct: 568 WVPYLQKFYSGEEGLDTQVKVRVDQIDPGVAKAI 601
[40][TOP]
>UniRef100_Q6MP96 DNA topoisomerase n=1 Tax=Bdellovibrio bacteriovorus
RepID=Q6MP96_BDEBA
Length = 909
Score = 121 bits (304), Expect = 3e-26
Identities = 70/154 (45%), Positives = 92/154 (59%), Gaps = 1/154 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + + V + LD H T PPARYT+ASLV+ +E G+GRPSTYAS++ T++ RGY
Sbjct: 468 LPALKVKDGVKCAKLDPTSHETKPPARYTEASLVQTMEKEGIGRPSTYASVIGTIIDRGY 527
Query: 248 VSR-GTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V + GT AL P TA +V +LL +Y +VD FT+EME+SLD IA G D
Sbjct: 528 VRKNGT----------ALVPTFTAMIVSKLLSQYLSQYVDLGFTSEMEQSLDNIADGELD 577
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
+ YL+S Y G GL A V +ID AR +
Sbjct: 578 WESYLASVYKGPKGLRAMVDNQGDKIDPNEARTM 611
[41][TOP]
>UniRef100_A2BV96 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9515
RepID=A2BV96_PROM5
Length = 870
Score = 121 bits (304), Expect = 3e-26
Identities = 64/147 (43%), Positives = 90/147 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP++ G + V++ + H T PARYT+A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 ILPNLTLGSTLEVASKEATYHETKSPARYTEAALVKVLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + +L+P TAF V LL +FP VD FTA+ME SLD I++G +
Sbjct: 518 YAN---------ISSNSLSPTFTAFAVTALLEEHFPDLVDTTFTAKMESSLDEISSGNLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL ++Y G +GL V + E +ID
Sbjct: 569 WLPYLETFYKGKNGLEVKVQKTEGDID 595
[42][TOP]
>UniRef100_C0ZNG9 DNA topoisomerase n=1 Tax=Rhodococcus erythropolis PR4
RepID=C0ZNG9_RHOE4
Length = 978
Score = 121 bits (303), Expect = 3e-26
Identities = 74/151 (49%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP +V G+ V + LD H+T PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 474 GQSDDAESRLPVLVKGQEVTATKLDPDGHSTNPPARYTEASLIKTLEELGIGRPSTYSSI 533
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T++ RGYV RG+ AL P AF V LL +F VD FTA ME L
Sbjct: 534 IKTILDRGYVYKRGS----------ALVPSWVAFAVIGLLEVHFGRLVDFDFTAGMEDDL 583
Query: 398 DAIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
DAIA G R +LSS+Y G + G SVAR
Sbjct: 584 DAIAGGREQRGNWLSSFYFGGETGAEGSVAR 614
[43][TOP]
>UniRef100_Q4C5N4 DNA topoisomerase n=1 Tax=Crocosphaera watsonii WH 8501
RepID=Q4C5N4_CROWT
Length = 880
Score = 121 bits (303), Expect = 3e-26
Identities = 69/154 (44%), Positives = 91/154 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ LD++ H T PPARYT+ASLVK LE GVGRPSTYASI+ T+ RG
Sbjct: 457 ILPPLEEGDHPDCKELDVLGHETQPPARYTEASLVKMLEGEGVGRPSTYASIIGTIRDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ +AL P TAF V LL +FP VDA FT++ME++LD IA G A
Sbjct: 517 Y---------AQMRGKALVPTFTAFAVVSLLETHFPDLVDAKFTSKMEQTLDEIATGEAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL + V +ID A+ +
Sbjct: 568 WVPYLKKFYSGEEGLDSQVKVGIDQIDPGVAKAI 601
[44][TOP]
>UniRef100_C3JWG9 DNA topoisomerase n=1 Tax=Rhodococcus erythropolis SK121
RepID=C3JWG9_RHOER
Length = 978
Score = 121 bits (303), Expect = 3e-26
Identities = 74/151 (49%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP +V G+ V + LD H+T PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 474 GQSDDAESRLPVLVKGQEVTATKLDPDGHSTNPPARYTEASLIKTLEELGIGRPSTYSSI 533
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T++ RGYV RG+ AL P AF V LL +F VD FTA ME L
Sbjct: 534 IKTILDRGYVYKRGS----------ALVPSWVAFAVIGLLEVHFGRLVDFDFTAGMEDDL 583
Query: 398 DAIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
DAIA G R +LSS+Y G + G SVAR
Sbjct: 584 DAIAGGREQRGNWLSSFYFGGETGAEGSVAR 614
[45][TOP]
>UniRef100_Q7V627 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9313
RepID=Q7V627_PROMM
Length = 916
Score = 120 bits (302), Expect = 4e-26
Identities = 65/152 (42%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPD+ + + ++ + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 475 LLPDLAVDDSPTLQDVEALGHQTQPPARYSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 534
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 535 YAA---------LQNNSLTPSFTAFAVTALLEEHFPDLVDTSFTARMEFTLDEISTGKVQ 585
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G GL + V + E +ID++ +R
Sbjct: 586 WLPYLEGFYKGEQGLESQVQQREGDIDSSVSR 617
[46][TOP]
>UniRef100_Q6AGT6 DNA topoisomerase n=1 Tax=Leifsonia xyli subsp. xyli
RepID=Q6AGT6_LEIXX
Length = 980
Score = 120 bits (302), Expect = 4e-26
Identities = 69/140 (49%), Positives = 86/140 (61%), Gaps = 1/140 (0%)
Frame = +2
Query: 47 STTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVE 226
S T LP + G+ ++V + H TTPP RYT+ASLVK LE LG+GRPST+ASI+
Sbjct: 497 SDTGESKLPPLTAGQTLSVQEVAADGHETTPPPRYTEASLVKSLEELGIGRPSTFASIIS 556
Query: 227 TLVLRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDA 403
T++ RGYV+ RG QAL P AF V +LL YF V FTAEME LD
Sbjct: 557 TIIDRGYVTQRG----------QALVPSWVAFSVVRLLEDYFGDLVQYDFTAEMEDDLDR 606
Query: 404 IAAGAADRQEYLSSYYLGSD 463
IA G A R ++L+S+Y GSD
Sbjct: 607 IAGGVAARVDWLNSFYFGSD 626
[47][TOP]
>UniRef100_Q5Z2Y2 DNA topoisomerase n=1 Tax=Nocardia farcinica RepID=Q5Z2Y2_NOCFA
Length = 976
Score = 120 bits (302), Expect = 4e-26
Identities = 74/151 (49%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP + G+ V L+ H+T PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 483 GQSDDAESRLPALEEGQNVTAVELNPDGHSTNPPARYTEASLIKALEELGIGRPSTYSSI 542
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T++ RGYV RG+ AL P AF V LL YF VD FTA ME L
Sbjct: 543 IKTILDRGYVYKRGS----------ALVPSWVAFAVVGLLEAYFGRLVDFDFTAAMEDDL 592
Query: 398 DAIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
DAIA+G R +LSS+Y G D G+ SVAR
Sbjct: 593 DAIASGRERRGNWLSSFYFGGDSGVEGSVAR 623
[48][TOP]
>UniRef100_A6C5M1 DNA topoisomerase n=1 Tax=Planctomyces maris DSM 8797
RepID=A6C5M1_9PLAN
Length = 909
Score = 120 bits (302), Expect = 4e-26
Identities = 64/147 (43%), Positives = 90/147 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + + + S ++ ++H T PPARYT+A++V++LE+ GVGRPSTYASI+ T+ RG
Sbjct: 464 MLPPLEENQALEASEVEPLKHETKPPARYTEATIVRKLESEGVGRPSTYASIIGTIQDRG 523
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV + + L P TA V +LL ++FP+ VD FTA ME+ LD IA G D
Sbjct: 524 YVKKTGSQ---------LVPTFTALAVTRLLEKFFPNLVDLQFTAAMEQELDDIAVGEGD 574
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
R YL+ +Y G GL V E+ ID
Sbjct: 575 RLPYLNQFYRGEAGLDEQVKAKEETID 601
[49][TOP]
>UniRef100_A3Z0K4 DNA topoisomerase n=1 Tax=Synechococcus sp. WH 5701
RepID=A3Z0K4_9SYNE
Length = 917
Score = 120 bits (302), Expect = 4e-26
Identities = 66/154 (42%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + + A + ++ + H T PPARY++A+LVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPSLAVDDRPACAGVEALGHQTQPPARYSEAALVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L AL P TAF V LL +FP VD +FTA ME SLD I+ G +
Sbjct: 518 YAT---------LAGHALTPSFTAFAVTALLEGHFPDLVDTSFTARMESSLDEISTGKLE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL+ +Y G GL V + E +ID +R +
Sbjct: 569 WLPYLTDFYKGEKGLETQVQQREDDIDPTVSRTI 602
[50][TOP]
>UniRef100_Q47L55 DNA topoisomerase n=1 Tax=Thermobifida fusca YX RepID=Q47L55_THEFY
Length = 906
Score = 120 bits (300), Expect = 8e-26
Identities = 65/133 (48%), Positives = 83/133 (62%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+P+ ++D H+T PPARYT+ASLVKELE +GRPSTYA+I+ T++ RGY
Sbjct: 488 LPPLTEGDPLHAQSVDAEGHSTRPPARYTEASLVKELEEREIGRPSTYATIIGTILERGY 547
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V QLL R+F VD FTA ME LDAIA G A+R
Sbjct: 548 VFK---------KGSALVPSFLAFAVVQLLERHFSHLVDYDFTARMEDVLDAIARGEAER 598
Query: 428 QEYLSSYYLGSDG 466
+L +Y G+DG
Sbjct: 599 VPWLRRFYFGADG 611
[51][TOP]
>UniRef100_A2C7C2 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. MIT 9303
RepID=A2C7C2_PROM3
Length = 916
Score = 120 bits (300), Expect = 8e-26
Identities = 65/152 (42%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPD+ + + ++ + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 475 LLPDLAVDDSPTLQDVEALGHQTQPPARYSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 534
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 535 YAA---------LQNNSLIPSFTAFAVTALLEEHFPDLVDTSFTARMEFTLDEISTGKVQ 585
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G GL + V + E +ID++ +R
Sbjct: 586 WLPYLEGFYKGEKGLESQVQQREGDIDSSVSR 617
[52][TOP]
>UniRef100_Q3AWJ8 DNA topoisomerase n=1 Tax=Synechococcus sp. CC9902
RepID=Q3AWJ8_SYNS9
Length = 899
Score = 119 bits (299), Expect = 1e-25
Identities = 65/154 (42%), Positives = 88/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ +D + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPSLAIGDKPQPKDVDALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + AL P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 518 YAT---------IQGNALTPSFTAFAVTALLEEHFPDLVDTSFTARMENTLDEISHGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL V + E +ID +R +
Sbjct: 569 WLPYLEGFYKGEEGLETQVQQREGDIDPGASRTI 602
[53][TOP]
>UniRef100_B0JHS3 DNA topoisomerase n=1 Tax=Microcystis aeruginosa NIES-843
RepID=B0JHS3_MICAN
Length = 878
Score = 119 bits (297), Expect = 2e-25
Identities = 63/152 (41%), Positives = 91/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ L+ + H T PPARY++ASLVK LE+ G+GRPSTYA+I+ T++ RG
Sbjct: 457 ILPALSVGDTPNCRQLEAISHDTQPPARYSEASLVKTLESEGIGRPSTYATILGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ + L P TAF V LL +FP VD FT++ME +LD IA G+A
Sbjct: 517 Y---------AQMRNKTLIPTFTAFAVVSLLENHFPDLVDPKFTSKMEETLDDIATGSAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G GL + V E +I+++ A+
Sbjct: 568 WLPYLDRFYRGEKGLESQVKERESQINSSTAK 599
[54][TOP]
>UniRef100_Q05YT5 DNA topoisomerase n=1 Tax=Synechococcus sp. BL107
RepID=Q05YT5_9SYNE
Length = 899
Score = 119 bits (297), Expect = 2e-25
Identities = 65/154 (42%), Positives = 87/154 (56%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ +D + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPSLAVGDKPQPKDVDALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + + AL P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 518 YAT---------IQGNALTPSFTAFAVTALLEEHFPDLVDTSFTARMENTLDEISHGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL V + E +ID +R +
Sbjct: 569 WLPYLEGFYKGEQGLETQVHQREGDIDPGASRTI 602
[55][TOP]
>UniRef100_B1MGQ4 DNA topoisomerase n=1 Tax=Mycobacterium abscessus ATCC 19977
RepID=B1MGQ4_MYCA9
Length = 930
Score = 118 bits (296), Expect = 2e-25
Identities = 70/142 (49%), Positives = 88/142 (61%), Gaps = 2/142 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ V V+ L HTT PPARYT+ASL+K LE LG+GRPSTY+SI+ T+ RGY
Sbjct: 475 LPQLRQGQSVTVAELSADGHTTNPPARYTEASLIKALEELGIGRPSTYSSIIRTIQDRGY 534
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG+ AL P TAF V LL ++F VD FTA ME LD IA+G
Sbjct: 535 VHKRGS----------ALVPSWTAFAVIGLLEQHFGRLVDYDFTAAMEDDLDEIASGNER 584
Query: 425 RQEYLSSYYLGSD-GLAASVAR 487
R +L+++Y G D G+ SVAR
Sbjct: 585 RTNWLNAFYFGGDHGVEGSVAR 606
[56][TOP]
>UniRef100_Q05WM0 DNA topoisomerase n=1 Tax=Synechococcus sp. RS9916
RepID=Q05WM0_9SYNE
Length = 916
Score = 118 bits (296), Expect = 2e-25
Identities = 65/152 (42%), Positives = 87/152 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 473 LLPALKAGDSPSPQEVEALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 532
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L AL P TAF V LL +FP VD FTA ME +LD I+ G
Sbjct: 533 YAT---------LQSNALTPSFTAFAVTSLLEEHFPDLVDPGFTARMENTLDEISHGQVQ 583
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G +GL V + E +ID +R
Sbjct: 584 WLPYLEGFYKGDEGLEHQVQQREGDIDAGASR 615
[57][TOP]
>UniRef100_B2HJ79 DNA topoisomerase n=1 Tax=Mycobacterium marinum M
RepID=B2HJ79_MYCMM
Length = 934
Score = 118 bits (295), Expect = 3e-25
Identities = 68/150 (45%), Positives = 90/150 (60%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP++ PG+ + L HTT PPARYT+ASLVK E LG+GRPSTY I
Sbjct: 481 GEADDAERRLPNLTPGQRLDAVELTPDGHTTNPPARYTEASLVKAFEELGIGRPSTYTPI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGHLVDYGFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIA+G R ++L+++Y G D G++ SVAR
Sbjct: 592 AIASGQERRTDWLNNFYFGGDHGVSDSVAR 621
[58][TOP]
>UniRef100_A5GMZ4 DNA topoisomerase n=1 Tax=Synechococcus sp. WH 7803
RepID=A5GMZ4_SYNPW
Length = 905
Score = 118 bits (295), Expect = 3e-25
Identities = 64/154 (41%), Positives = 89/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPSLSVGDAPSLKEVEALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD FTA ME +LD I+ G
Sbjct: 518 YAT---------LLNNSLTPSFTAFAVTSLLEEHFPDLVDPGFTARMENTLDEISHGTVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL + V + E +ID +R +
Sbjct: 569 WLPYLEGFYKGDQGLESQVHQREGDIDPGASRTI 602
[59][TOP]
>UniRef100_C2AJX7 DNA topoisomerase n=1 Tax=Tsukamurella paurometabola DSM 20162
RepID=C2AJX7_TSUPA
Length = 968
Score = 118 bits (295), Expect = 3e-25
Identities = 67/148 (45%), Positives = 86/148 (58%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + G+ V + L +H T+PPARYT+ASLVK LE LG+GRPSTYASI
Sbjct: 472 GEADDAESRLPQLTKGQRVTAAELTAADHVTSPPARYTEASLVKTLEELGIGRPSTYASI 531
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P+ AF V LL +F VD FTA ME LD
Sbjct: 532 IKTIQDRGYVVK---------KGNALVPQWVAFAVIGLLEGHFGGLVDYNFTASMEDDLD 582
Query: 401 AIAAGAADRQEYLSSYYLGSDGLAASVA 484
IA G R ++L+ +Y G G AA+ A
Sbjct: 583 EIAGGREGRVDWLTRFYFGDAGDAAAAA 610
[60][TOP]
>UniRef100_UPI000197631C DNA topoisomerase I n=1 Tax=Bifidobacterium bifidum NCIMB 41171
RepID=UPI000197631C
Length = 972
Score = 117 bits (294), Expect = 4e-25
Identities = 74/169 (43%), Positives = 98/169 (57%), Gaps = 8/169 (4%)
Frame = +2
Query: 2 SAPVSSS-------AMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDA 160
+AP +SS A + R T LP + G+ +A S+++ H T PPARYT+A
Sbjct: 462 AAPAASSMGAGDGEAAAKRASRETDDNGSLPPMQTGDRLAASSVEADGHETQPPARYTEA 521
Query: 161 SLVKELEALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLL 337
SLVK LEA +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL
Sbjct: 522 SLVKTLEAKEIGRPSTYASIISTIIDRGYVYERG----------RALIPSWLAFSVIKLL 571
Query: 338 RRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAASVA 484
FP +VD FTA+ME LD IA G +++L+ +Y GS G AA+ A
Sbjct: 572 ETKFPKYVDYQFTADMENGLDQIAHGQETGRDWLTHFYFGSGGDAATSA 620
[61][TOP]
>UniRef100_C4LLJ1 DNA topoisomerase n=1 Tax=Corynebacterium kroppenstedtii DSM 44385
RepID=C4LLJ1_CORK4
Length = 987
Score = 117 bits (294), Expect = 4e-25
Identities = 66/144 (45%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + + ++ H+TTPPARYT+ASLVK++E LG+GRPSTYASI++T+
Sbjct: 481 AEKRLPVLTEGQGLTATDIEADGHSTTPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQ 540
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV SRG AL P AF V LL + F S +D FT+ ME LD+IA
Sbjct: 541 DRGYVYSRG----------NALVPSWVAFAVVGLLEQNFGSLIDYDFTSSMEDVLDSIAN 590
Query: 413 GAADRQEYLSSYYLGSDGLAASVA 484
G+ DR +L +Y G DG +++ A
Sbjct: 591 GSEDRSHWLEGFYYGDDGASSAKA 614
[62][TOP]
>UniRef100_B0RAE2 DNA topoisomerase n=1 Tax=Clavibacter michiganensis subsp.
sepedonicus RepID=B0RAE2_CLAMS
Length = 1012
Score = 117 bits (294), Expect = 4e-25
Identities = 69/154 (44%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A S R G + LPD+ G+ + + +D H T+PP RYT+ASLVK LE
Sbjct: 491 AAYEESRDEERHGAAEPREAKLPDLKKGQDLRLVDVDAKGHETSPPPRYTEASLVKTLEE 550
Query: 185 LGVGRPSTYASIVETLVLRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYA+I+ T+V RGYV+ RGT AL P AF V +LL +F V
Sbjct: 551 LGIGRPSTYAAIISTIVDRGYVTPRGT----------ALVPNWIAFSVVRLLEEFFTELV 600
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSD 463
FTA ME LD IA GAA+R ++L +Y G+D
Sbjct: 601 QYDFTAGMEDDLDRIAEGAAERVDWLKGFYYGND 634
[63][TOP]
>UniRef100_Q7U539 DNA topoisomerase n=1 Tax=Synechococcus sp. WH 8102
RepID=Q7U539_SYNPX
Length = 900
Score = 117 bits (293), Expect = 5e-25
Identities = 65/152 (42%), Positives = 87/152 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ A ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPALAVGDAPAPKQVEPLGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L AL P TAF V LL +FP VD +FTA ME +LD I+ G +
Sbjct: 518 Y---------STLQGNALTPSFTAFAVTALLEEHFPDLVDTSFTARMENTLDEISHGKVE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL ++ G GL V + E +ID +R
Sbjct: 569 WLPYLEGFFKGDQGLETQVQQREGDIDPGASR 600
[64][TOP]
>UniRef100_C7NG59 DNA topoisomerase I n=1 Tax=Kytococcus sedentarius DSM 20547
RepID=C7NG59_KYTSD
Length = 963
Score = 117 bits (293), Expect = 5e-25
Identities = 64/140 (45%), Positives = 84/140 (60%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ +A S ++ + H T+PP RYT+A+LVK LE G+GRPSTYA+ V T+ RGY
Sbjct: 490 LPKMAAGQELATSRVEALGHETSPPPRYTEATLVKALEEKGIGRPSTYAATVGTIQDRGY 549
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R AL P AF V LL ++FP+ VD FTA ME LDAIAAG DR
Sbjct: 550 V---------RTKGNALVPTWLAFAVTTLLEKHFPTLVDYDFTASMEEGLDAIAAGEEDR 600
Query: 428 QEYLSSYYLGSDGLAASVAR 487
+L +Y G + +A+ R
Sbjct: 601 VAWLQRFYFGDEASSATGLR 620
[65][TOP]
>UniRef100_A4CRQ0 DNA topoisomerase n=1 Tax=Synechococcus sp. WH 7805
RepID=A4CRQ0_SYNPV
Length = 930
Score = 117 bits (293), Expect = 5e-25
Identities = 64/154 (41%), Positives = 89/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 483 LLPSLSVGDAPSLKDVEALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 542
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD FTA ME +LD I+ G
Sbjct: 543 YAT---------LLNNSLTPSFTAFAVTSLLEEHFPDLVDPGFTARMENTLDEISHGTVQ 593
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G GL + V + E +ID +R +
Sbjct: 594 WLPYLEGFYKGDKGLESQVHQREGDIDPGASRTI 627
[66][TOP]
>UniRef100_UPI0001AF72C6 DNA topoisomerase I n=1 Tax=Mycobacterium kansasii ATCC 12478
RepID=UPI0001AF72C6
Length = 931
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + L H T PP RYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIAAG R +L+++Y G + G+A SVAR
Sbjct: 592 AIAAGTERRTNWLNNFYFGGEHGVADSVAR 621
[67][TOP]
>UniRef100_UPI00019019BC DNA topoisomerase I n=1 Tax=Mycobacterium tuberculosis T17
RepID=UPI00019019BC
Length = 934
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G D G+ SVAR
Sbjct: 592 EIAAGNERRTNWLNNFYFGGDHGVPDSVAR 621
[68][TOP]
>UniRef100_UPI0001901374 DNA topoisomerase I n=1 Tax=Mycobacterium tuberculosis T92
RepID=UPI0001901374
Length = 934
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G D G+ SVAR
Sbjct: 592 EIAAGNERRTNWLNNFYFGGDHGVPDSVAR 621
[69][TOP]
>UniRef100_A1KPX5 DNA topoisomerase n=2 Tax=Mycobacterium bovis BCG
RepID=A1KPX5_MYCBP
Length = 934
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G D G+ SVAR
Sbjct: 592 EIAAGNERRTNWLNNFYFGGDHGVPDSVAR 621
[70][TOP]
>UniRef100_C4V2Y3 DNA topoisomerase n=1 Tax=Selenomonas flueggei ATCC 43531
RepID=C4V2Y3_9FIRM
Length = 776
Score = 117 bits (292), Expect = 6e-25
Identities = 58/129 (44%), Positives = 80/129 (62%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPD+V G+P+ + AL+ +H T PP RY DAS+VK LE LG+GRPSTYA I+ET+ RG
Sbjct: 473 LLPDLVDGDPLTLGALNPEQHFTEPPPRYNDASIVKALEELGIGRPSTYAPIIETIQKRG 532
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV R ++ P F+V +L +F + VD FTA +E LD +A G+ D
Sbjct: 533 YVERREKQ---------FRPTELGFIVTDMLEEHFKNIVDVKFTANLEGELDGVADGSLD 583
Query: 425 RQEYLSSYY 451
+ E L S+Y
Sbjct: 584 KNELLGSFY 592
[71][TOP]
>UniRef100_A8YFB6 DNA topoisomerase n=1 Tax=Microcystis aeruginosa PCC 7806
RepID=A8YFB6_MICAE
Length = 878
Score = 117 bits (292), Expect = 6e-25
Identities = 62/152 (40%), Positives = 90/152 (59%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ L+ + H T PP RY++ASLVK LE+ G+GRPSTYA+I+ T++ RG
Sbjct: 457 ILPPLSVGDTPNCRQLEAISHDTQPPTRYSEASLVKTLESEGIGRPSTYATILGTIIDRG 516
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y ++ + L P TAF V LL +FP VD FT++ME +LD IA G+A
Sbjct: 517 Y---------AQMRNKTLIPTFTAFAVVGLLENHFPDLVDPKFTSKMEETLDDIATGSAQ 567
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL +Y G GL + V E +I+++ A+
Sbjct: 568 WLPYLDRFYRGEKGLESQVKERESQINSSTAK 599
[72][TOP]
>UniRef100_A5WTL1 DNA topoisomerase n=1 Tax=Mycobacterium tuberculosis F11
RepID=A5WTL1_MYCTF
Length = 934
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G D G+ SVAR
Sbjct: 592 EIAAGNERRTNWLNNFYFGGDHGVPDSVAR 621
[73][TOP]
>UniRef100_P0A621 DNA topoisomerase 1 n=6 Tax=Mycobacterium tuberculosis complex
RepID=TOP1_MYCBO
Length = 934
Score = 117 bits (292), Expect = 6e-25
Identities = 69/150 (46%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + PG+ + + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 481 GEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G D G+ SVAR
Sbjct: 592 EIAAGNERRTNWLNNFYFGGDHGVPDSVAR 621
[74][TOP]
>UniRef100_A5CPG7 DNA topoisomerase n=1 Tax=Clavibacter michiganensis subsp.
michiganensis NCPPB 382 RepID=A5CPG7_CLAM3
Length = 984
Score = 116 bits (291), Expect = 8e-25
Identities = 68/154 (44%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A S R G + LPD+ G+ + + +D H T+PP RYT+ASLVK LE
Sbjct: 449 AAYEESRDEERHGAAEPREAKLPDLKKGQDLRLVDVDAKGHETSPPPRYTEASLVKTLEE 508
Query: 185 LGVGRPSTYASIVETLVLRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYA+I+ T+V RGYV+ RGT AL P AF V +LL +F V
Sbjct: 509 LGIGRPSTYAAIISTIVDRGYVTPRGT----------ALVPNWIAFSVVRLLEEFFTELV 558
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSD 463
FTA ME LD IA G+A+R ++L +Y G+D
Sbjct: 559 QYDFTAGMEDDLDRIAEGSAERVDWLKGFYYGND 592
[75][TOP]
>UniRef100_Q3AM11 DNA topoisomerase n=1 Tax=Synechococcus sp. CC9605
RepID=Q3AM11_SYNSC
Length = 899
Score = 116 bits (290), Expect = 1e-24
Identities = 65/154 (42%), Positives = 88/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPALSVGDAPEPKTVEPLGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L AL P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 518 YAT---------LLGNALTPSFTAFAVTALLEEHFPELVDTSFTARMENTLDEISHGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL V + E +ID +R +
Sbjct: 569 WLPYLEGFYKGDEGLENQVQQREGDIDPGASRTI 602
[76][TOP]
>UniRef100_Q0I8A6 DNA topoisomerase n=1 Tax=Synechococcus sp. CC9311
RepID=Q0I8A6_SYNS3
Length = 905
Score = 116 bits (290), Expect = 1e-24
Identities = 64/154 (41%), Positives = 89/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPALNVGDSPKIHDVEALGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y S L +L P TAF V LL +FP VD FTA ME +LD I+ G
Sbjct: 518 YSS---------LNNNSLTPSFTAFAVTALLEEHFPDLVDTGFTARMETTLDEISTGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++ G +GL + V + E +ID +R +
Sbjct: 569 WLPYLDGFFKGDEGLESLVQKREGDIDPGASRTI 602
[77][TOP]
>UniRef100_A2C0P3 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. NATL1A
RepID=A2C0P3_PROM1
Length = 968
Score = 116 bits (290), Expect = 1e-24
Identities = 64/147 (43%), Positives = 83/147 (56%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 460 LLPKLAVGDSPTAKNVEALGHQTQPPARYSEASLVKTLEKEGIGRPSTYASIIGTIVDRG 519
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L +L P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 520 Y---------SVLNNNSLTPSFTAFAVTALLEEHFPDLVDTSFTARMESTLDEISTGKVS 570
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL +Y G GL V + E +ID
Sbjct: 571 WLPYLKGFYKGDTGLENQVQQREGDID 597
[78][TOP]
>UniRef100_D0CLR2 DNA topoisomerase I n=1 Tax=Synechococcus sp. WH 8109
RepID=D0CLR2_9SYNE
Length = 899
Score = 116 bits (290), Expect = 1e-24
Identities = 65/154 (42%), Positives = 88/154 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ + H T PPAR+++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 458 LLPALSVGDAPEPKTVEPLGHQTQPPARFSEASLVKMLEKEGIGRPSTYASIIGTIVDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L AL P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 518 YAT---------LLGNALTPSFTAFAVTALLEEHFPELVDTSFTARMENTLDEISHGKVQ 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL +Y G +GL V + E +ID +R +
Sbjct: 569 WLPYLEGFYKGDEGLENQVQQREGDIDPGASRTI 602
[79][TOP]
>UniRef100_C8NKH1 Dna topoisomerase n=2 Tax=Corynebacterium efficiens
RepID=C8NKH1_COREF
Length = 999
Score = 116 bits (290), Expect = 1e-24
Identities = 71/149 (47%), Positives = 89/149 (59%), Gaps = 5/149 (3%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + + + H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+
Sbjct: 477 AEKRLPRLTEGDALTATDITADGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQ 536
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV SRG AL P AF V LL F S VD FT+ ME LD IAA
Sbjct: 537 DRGYVYSRG----------NALVPSWVAFAVVGLLEANFTSLVDYDFTSSMEDELDNIAA 586
Query: 413 GAADRQEYLSSYYLG----SDGLAASVAR 487
G R E+LS +Y G D +A SVAR
Sbjct: 587 GREGRTEWLSGFYFGDAEADDSMAESVAR 615
[80][TOP]
>UniRef100_C7R1J9 DNA topoisomerase I n=1 Tax=Jonesia denitrificans DSM 20603
RepID=C7R1J9_JONDD
Length = 923
Score = 116 bits (290), Expect = 1e-24
Identities = 65/134 (48%), Positives = 82/134 (61%), Gaps = 1/134 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP +V G+P+A + HTTTPP R+T+ASLVK LE G+GRPSTYAS + T+ RGY
Sbjct: 474 LPHMVEGDPLASRDVSADGHTTTPPPRFTEASLVKALEERGIGRPSTYASTISTIQDRGY 533
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +RG QAL P AF V +LL +F +D FTA+ME LD IAAG D
Sbjct: 534 VNNRG----------QALVPSWLAFSVIRLLEEHFSQLIDYDFTAQMESDLDEIAAGQGD 583
Query: 425 RQEYLSSYYLGSDG 466
R +L+ +Y G G
Sbjct: 584 RVNWLTQFYFGGAG 597
[81][TOP]
>UniRef100_C5V9G5 DNA topoisomerase n=1 Tax=Corynebacterium matruchotii ATCC 14266
RepID=C5V9G5_9CORY
Length = 986
Score = 115 bits (289), Expect = 1e-24
Identities = 72/162 (44%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 17 SSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVG 196
S A++ +S LP + G+ VA+S + EHTT PPARYT+ASLVK++E LG+G
Sbjct: 464 SDAIADAAASSDANQSRLPHLKVGDEVAISDVAADEHTTNPPARYTEASLVKKMEDLGIG 523
Query: 197 RPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAF 373
RPSTYASI++T+ RGYV SRG AL P AF V L+ + F + VD F
Sbjct: 524 RPSTYASIIKTIQDRGYVYSRG----------NALVPSWVAFAVVGLMEKSFAALVDYDF 573
Query: 374 TAEMERSLDAIAAGAADRQEYLSSYYLG----SDGLAASVAR 487
T+ ME LD IAAG +L +Y G SD A ++AR
Sbjct: 574 TSSMEDELDDIAAGNEVGANWLKGFYFGDKHASDATAETIAR 615
[82][TOP]
>UniRef100_C0E5R1 DNA topoisomerase n=1 Tax=Corynebacterium matruchotii ATCC 33806
RepID=C0E5R1_9CORY
Length = 986
Score = 115 bits (289), Expect = 1e-24
Identities = 72/162 (44%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 17 SSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVG 196
S A++ +S LP + G+ VA+S + EHTT PPARYT+ASLVK++E LG+G
Sbjct: 464 SDAIADAAASSDANQSRLPHLKVGDEVAISDVAADEHTTNPPARYTEASLVKKMEDLGIG 523
Query: 197 RPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAF 373
RPSTYASI++T+ RGYV SRG AL P AF V L+ + F + VD F
Sbjct: 524 RPSTYASIIKTIQDRGYVYSRG----------NALVPSWVAFAVVGLMEKSFAALVDYDF 573
Query: 374 TAEMERSLDAIAAGAADRQEYLSSYYLG----SDGLAASVAR 487
T+ ME LD IAAG +L +Y G SD A ++AR
Sbjct: 574 TSSMEDELDDIAAGNEVGANWLKGFYFGDKHASDATAETIAR 615
[83][TOP]
>UniRef100_Q46GY2 DNA topoisomerase n=1 Tax=Prochlorococcus marinus str. NATL2A
RepID=Q46GY2_PROMT
Length = 968
Score = 115 bits (288), Expect = 2e-24
Identities = 64/147 (43%), Positives = 83/147 (56%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ ++ + H T PPARY++ASLVK LE G+GRPSTYASI+ T+V RG
Sbjct: 460 LLPKLEVGDSPTAKNVEALGHQTQPPARYSEASLVKTLEKEGIGRPSTYASIIGTIVDRG 519
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L +L P TAF V LL +FP VD +FTA ME +LD I+ G
Sbjct: 520 Y---------SVLNNNSLTPSFTAFAVTALLEEHFPDLVDTSFTARMESTLDEISTGKVS 570
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
YL +Y G GL V + E +ID
Sbjct: 571 WLPYLKGFYKGDTGLENQVQQREGDID 597
[84][TOP]
>UniRef100_A4T5R5 DNA topoisomerase n=1 Tax=Mycobacterium gilvum PYR-GCK
RepID=A4T5R5_MYCGI
Length = 941
Score = 115 bits (288), Expect = 2e-24
Identities = 67/150 (44%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP++ G+ V L HTT+PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 476 GEADDAESRLPNLTQGQRVDAKDLTADGHTTSPPARYTEASLIKALEDLGIGRPSTYSSI 535
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 536 IKTIQDRGYVHK---------KGSALVPSWVAFAVIGLLEQHFSRLVDYDFTAAMEDELD 586
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G + G+ S+AR
Sbjct: 587 EIAAGNERRTNWLNNFYFGGEHGVEGSIAR 616
[85][TOP]
>UniRef100_C1ZEL8 DNA topoisomerase n=1 Tax=Planctomyces limnophilus DSM 3776
RepID=C1ZEL8_PLALI
Length = 895
Score = 115 bits (288), Expect = 2e-24
Identities = 67/155 (43%), Positives = 84/155 (54%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + LP + G+ + + + H T PPARYT+A+LVK LE G+GRPSTYASI
Sbjct: 456 GALEDSEAALPPMEKGQKLTCKEVQALAHETKPPARYTEATLVKTLEEEGIGRPSTYASI 515
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGYV R L P TA V +LL + F VD FTA ME+ LD
Sbjct: 516 IGTIQDRGYV---------RKQGNQLVPTFTAMAVTKLLEKNFSRLVDLQFTARMEQDLD 566
Query: 401 AIAAGAADRQEYLSSYYLGSDGLAASVARMEKEID 505
IA G A+R YL S+Y G GL V + E ID
Sbjct: 567 DIANGQAERLPYLKSFYSGETGLDEQVKQNEAGID 601
[86][TOP]
>UniRef100_A4AKC9 DNA topoisomerase n=1 Tax=marine actinobacterium PHSC20C1
RepID=A4AKC9_9ACTN
Length = 939
Score = 115 bits (288), Expect = 2e-24
Identities = 65/144 (45%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +2
Query: 35 RPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYA 214
R T+ LP + G+ + + ++ H T+PP RYT+ASLVK+LE LG+GRPSTYA
Sbjct: 456 RNATAEPKEAKLPPLKEGQTLTLLDIEAKGHETSPPPRYTEASLVKKLEELGIGRPSTYA 515
Query: 215 SIVETLVLRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMER 391
SI+ T++ RGY++ RG QAL P AF V +LL YF V FTA ME
Sbjct: 516 SIISTIIDRGYITPRG----------QALVPNWIAFSVIRLLEEYFGDLVQYDFTAGMED 565
Query: 392 SLDAIAAGAADRQEYLSSYYLGSD 463
LD IA G+ +R E+L S+Y G D
Sbjct: 566 DLDRIAGGSQNRVEWLKSFYFGDD 589
[87][TOP]
>UniRef100_UPI0001B46014 DNA topoisomerase I n=1 Tax=Mycobacterium intracellulare ATCC 13950
RepID=UPI0001B46014
Length = 937
Score = 115 bits (287), Expect = 2e-24
Identities = 68/150 (45%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + G+ + L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 478 GEADDAESRLPQLTQGQRLDAIELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 537
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 538 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 588
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIA+G R ++L+++Y G + G+A SVAR
Sbjct: 589 AIASGQERRTDWLNNFYFGGEHGVADSVAR 618
[88][TOP]
>UniRef100_Q0RBI4 DNA topoisomerase n=1 Tax=Frankia alni ACN14a RepID=Q0RBI4_FRAAA
Length = 1036
Score = 115 bits (287), Expect = 2e-24
Identities = 68/140 (48%), Positives = 86/140 (61%), Gaps = 1/140 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LPDV G+P+AV +L HTT+PPAR+T+ASLVK LE LG+GRPSTYASI+ T+ RGY
Sbjct: 529 LPDVRQGDPLAVRSLTPRGHTTSPPARFTEASLVKTLEELGIGRPSTYASIIGTIQDRGY 588
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V LL +F VD FTA ME LD IAAG +
Sbjct: 589 VWK---------KGSALVPSFVAFAVVGLLEDHFGRLVDYRFTATMEDDLDDIAAGTSAS 639
Query: 428 QEYLSSYYLGS-DGLAASVA 484
++L+ +Y G+ DG + A
Sbjct: 640 TDWLTRFYFGTGDGTDPATA 659
[89][TOP]
>UniRef100_A8LF30 DNA topoisomerase n=1 Tax=Frankia sp. EAN1pec RepID=A8LF30_FRASN
Length = 1023
Score = 114 bits (286), Expect = 3e-24
Identities = 65/130 (50%), Positives = 79/130 (60%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LPDV G+P+A L HTT+PP R+T+ASLVK LE LG+GRPSTYASI+ T+ RGY
Sbjct: 546 LPDVRRGDPLATRTLTPRGHTTSPPPRFTEASLVKTLEELGIGRPSTYASIIGTIQDRGY 605
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V LL +F VD FTA ME LDAIAAG A
Sbjct: 606 VWK---------KGSALVPSFVAFAVVGLLEDHFTRLVDYQFTASMEDDLDAIAAGTAAS 656
Query: 428 QEYLSSYYLG 457
++L+ +Y G
Sbjct: 657 TDWLTGFYFG 666
[90][TOP]
>UniRef100_A1TG67 DNA topoisomerase n=1 Tax=Mycobacterium vanbaalenii PYR-1
RepID=A1TG67_MYCVP
Length = 955
Score = 114 bits (286), Expect = 3e-24
Identities = 67/150 (44%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP++ G+ V L HTT+PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 494 GEADDAESRLPNLTQGQRVDAKGLTADGHTTSPPARYTEASLIKALEDLGIGRPSTYSSI 553
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 554 IKTIQDRGYVHK---------KGSALVPSWVAFAVIGLLEQHFGRLVDYDFTAAMEDELD 604
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IAAG R +L+++Y G + G S+AR
Sbjct: 605 EIAAGHERRTNWLNNFYFGGEHGADGSIAR 634
[91][TOP]
>UniRef100_Q2J4Z1 DNA topoisomerase n=1 Tax=Frankia sp. CcI3 RepID=Q2J4Z1_FRASC
Length = 1049
Score = 114 bits (285), Expect = 4e-24
Identities = 71/154 (46%), Positives = 87/154 (56%), Gaps = 8/154 (5%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LPDV G+P+ +L HTT+PPAR+T+ASLVK LE LG+GRPSTYASI+ T+ RGY
Sbjct: 572 LPDVRQGDPLTTRSLTPRGHTTSPPARFTEASLVKTLEELGIGRPSTYASIIGTIQDRGY 631
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V LL +F VD FTA ME LD IAAG A
Sbjct: 632 VWK---------KGSALVPSFVAFAVVGLLEDHFTRLVDYRFTATMEDDLDDIAAGTAAS 682
Query: 428 QEYLSSYYLG--------SDGLAASVARMEKEID 505
++L+ +Y G +DGL V EID
Sbjct: 683 TDWLTRFYFGTGDGTDPAADGLKHLVNERLGEID 716
[92][TOP]
>UniRef100_A5GRQ4 DNA topoisomerase n=1 Tax=Synechococcus sp. RCC307
RepID=A5GRQ4_SYNR3
Length = 897
Score = 114 bits (285), Expect = 4e-24
Identities = 63/154 (40%), Positives = 90/154 (58%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + + + H T PPAR+++A+LVK LE G+GRPSTYASI+ T+ RG
Sbjct: 458 LLPTLRSGDHPSCQSCEPHGHQTQPPARFSEAALVKMLEKEGIGRPSTYASIIGTICDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y + L +L P TAF V LL +FP VD +FTA ME +LD I+ G+A+
Sbjct: 518 YAT---------LQNNSLTPSFTAFAVTALLEEHFPDLVDPSFTARMENTLDEISNGSAE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
YL ++ G GL VA+ E +ID +R +
Sbjct: 569 WLPYLDHFFRGDKGLEQQVAKREGDIDPVASRTI 602
[93][TOP]
>UniRef100_A1UML4 DNA topoisomerase n=3 Tax=Mycobacterium RepID=A1UML4_MYCSK
Length = 957
Score = 114 bits (285), Expect = 4e-24
Identities = 66/150 (44%), Positives = 87/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP++ G+ V L H T+PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 494 GESDDAESRLPNLTQGQRVDAKELTPAGHQTSPPARYTEASLIKALEDLGIGRPSTYSSI 553
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 554 IKTIQDRGYVHK---------KGSALVPSWVAFAVIGLLEQHFGRLVDYGFTAAMEDELD 604
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IA+G R +L ++Y G + G+ S+AR
Sbjct: 605 EIASGTERRTNWLKNFYFGGEHGVGDSIAR 634
[94][TOP]
>UniRef100_A0R5D9 DNA topoisomerase n=1 Tax=Mycobacterium smegmatis str. MC2 155
RepID=A0R5D9_MYCS2
Length = 936
Score = 114 bits (285), Expect = 4e-24
Identities = 66/150 (44%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G S A LP++ G+ V + L H T+PPARYT+ASL+K LE LG+GRPSTY+SI
Sbjct: 476 GESDDAESRLPNLTQGQRVDAADLSADGHQTSPPARYTEASLIKALEELGIGRPSTYSSI 535
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 536 IKTIQDRGYVQK---------KGSALVPSWVAFAVVGLLEQHFGRLVDYDFTAAMEDELD 586
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IA G R +L+++Y G + G+ S+AR
Sbjct: 587 EIANGQEQRTNWLNNFYFGGEHGVEGSIAR 616
[95][TOP]
>UniRef100_A0PV84 DNA topoisomerase n=1 Tax=Mycobacterium ulcerans Agy99
RepID=A0PV84_MYCUA
Length = 934
Score = 114 bits (285), Expect = 4e-24
Identities = 67/150 (44%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP++ PG+ + L HTT P ARYT+ASLVK E LG+GRPSTY I
Sbjct: 481 GEADDAERRLPNLTPGQRLDAVELTPDGHTTNPLARYTEASLVKAFEELGIGRPSTYTPI 540
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 541 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGHLVDYGFTAAMEDELD 591
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIA+G R ++L+++Y G D G++ SVAR
Sbjct: 592 AIASGQERRTDWLNNFYFGGDHGVSDSVAR 621
[96][TOP]
>UniRef100_C4DIT4 DNA topoisomerase n=1 Tax=Stackebrandtia nassauensis DSM 44728
RepID=C4DIT4_9ACTO
Length = 919
Score = 114 bits (285), Expect = 4e-24
Identities = 70/157 (44%), Positives = 91/157 (57%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP++ G+ + +L+ H T PPARYT+ASLVK LE G+GRPSTYASI
Sbjct: 457 GEADDAERRLPELERGQALTADSLEPAGHRTQPPARYTEASLVKALEERGIGRPSTYASI 516
Query: 221 VETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSL 397
++T+ RGYV RG QAL P AF V LL ++F VD FTA ME L
Sbjct: 517 MQTIQDRGYVFKRG----------QALIPAFLAFAVVGLLEKHFARLVDYDFTAGMESEL 566
Query: 398 DAIAAGAADRQEYLSSYYLG----SDGLAASVARMEK 496
D IAAG E+L S+Y G +DG A+ ++K
Sbjct: 567 DDIAAGEGRSLEFLRSFYFGGNNAADGTVAASGGLKK 603
[97][TOP]
>UniRef100_A3ZX95 DNA topoisomerase n=1 Tax=Blastopirellula marina DSM 3645
RepID=A3ZX95_9PLAN
Length = 925
Score = 114 bits (285), Expect = 4e-24
Identities = 63/150 (42%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+PV + HTT PP+R+++ASL + LE +G+GRPSTYASI++T++ R
Sbjct: 467 LLPSMKQGQPVDKDLFEPKSHTTQPPSRFSEASLTRSLEEMGIGRPSTYASIIDTILDRE 526
Query: 245 YV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV +GT ALAP F V +LL + P+ VD FTA+ME LDAI+ G A
Sbjct: 527 YVFKKGT----------ALAPTWLGFAVAKLLEEHLPNLVDYQFTAKMEDDLDAISRGEA 576
Query: 422 DRQEYLSSYYLGSD--GLAASVARMEKEID 505
++ YL +Y G + GL +V K++D
Sbjct: 577 EQNAYLKEFYFGHNEHGLKETVQAKIKDVD 606
[98][TOP]
>UniRef100_C1D174 DNA topoisomerase n=1 Tax=Deinococcus deserti VCD115
RepID=C1D174_DEIDV
Length = 966
Score = 114 bits (284), Expect = 5e-24
Identities = 68/150 (45%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ V + H T PPARYT+ASLV+ LEA G+GRPSTYASI+ T+ RGY
Sbjct: 467 LPPLKEGQQVTAETVRPESHETQPPARYTEASLVQALEAAGIGRPSTYASILGTIQDRGY 526
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
++ QAL P TAF LL +F VD FTA ME LD IA G A R
Sbjct: 527 ATK---------KGQALVPTWTAFATSALLEHHFGKLVDYDFTARMEEDLDDIAGGRASR 577
Query: 428 QEYLSSYYLGSDG----LAASVARMEKEID 505
YL +YLG +G L + R EID
Sbjct: 578 VPYLRRFYLGDEGQGMALKPLIDRQMGEID 607
[99][TOP]
>UniRef100_C7MGF4 DNA topoisomerase I n=1 Tax=Brachybacterium faecium DSM 4810
RepID=C7MGF4_BRAFD
Length = 904
Score = 114 bits (284), Expect = 5e-24
Identities = 68/136 (50%), Positives = 84/136 (61%), Gaps = 3/136 (2%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + AL HTTTPP RYT+ASLV+ LE G+GRPSTYAS V T+ RGY
Sbjct: 475 LPQMEEGQTLDTRALTPDGHTTTPPPRYTEASLVRALEDRGIGRPSTYASTVATVQDRGY 534
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RGT AL P TAF V +LL +F F+D FTA+ME+ LD +A G
Sbjct: 535 VLRRGT----------ALVPSWTAFAVVRLLEEHFGPFIDYDFTAQMEQQLDRMAQGDLA 584
Query: 425 RQEYLSSYYL--GSDG 466
R EYL ++YL G+DG
Sbjct: 585 RSEYLKNFYLSDGTDG 600
[100][TOP]
>UniRef100_C4RKW2 DNA topoisomerase n=1 Tax=Micromonospora sp. ATCC 39149
RepID=C4RKW2_9ACTO
Length = 935
Score = 114 bits (284), Expect = 5e-24
Identities = 63/134 (47%), Positives = 83/134 (61%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP++V +P+ AL H T PP+RYT+ASLVK LE LG+GRPSTYASI++T+
Sbjct: 472 AERRLPNLVKDQPLTADALAAQGHHTQPPSRYTEASLVKALEELGIGRPSTYASIMQTIQ 531
Query: 236 LRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAG 415
RGYVS+ QAL P AF V LL +++P VD FTA ME LD IA G
Sbjct: 532 DRGYVSK---------RGQALIPSFLAFAVIGLLEQHYPRLVDYNFTASMENELDEIAGG 582
Query: 416 AADRQEYLSSYYLG 457
++L+++Y G
Sbjct: 583 DHAAVDFLTAFYFG 596
[101][TOP]
>UniRef100_UPI0001AECAE4 DNA topoisomerase I n=1 Tax=Streptomyces albus J1074
RepID=UPI0001AECAE4
Length = 959
Score = 113 bits (283), Expect = 7e-24
Identities = 66/140 (47%), Positives = 82/140 (58%), Gaps = 1/140 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+P+A A+ + H+T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 476 LPQVSEGDPLAADAMSVDGHSTKPPARYTEASLVKELEEREIGRPSTYASILGTILDRGY 535
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 536 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 585
Query: 425 RQEYLSSYYLGSDGLAASVA 484
+L +Y G AA A
Sbjct: 586 AVPWLRRFYFGEGDAAAGTA 605
[102][TOP]
>UniRef100_Q6NJR6 DNA topoisomerase n=1 Tax=Corynebacterium diphtheriae
RepID=Q6NJR6_CORDI
Length = 964
Score = 113 bits (283), Expect = 7e-24
Identities = 72/166 (43%), Positives = 94/166 (56%), Gaps = 5/166 (3%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A V S ++ + A LP + G+ V L+ H+T PPARYT+ASLVK++E
Sbjct: 451 AYVEVSTLADGRDVADNAESHLPRLAEGDGVETKNLEADGHSTNPPARYTEASLVKKMED 510
Query: 185 LGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYASI++T+ RGYV SRG AL P AF V LL + F + V
Sbjct: 511 LGIGRPSTYASIIKTIQDRGYVYSRG----------NALVPSWVAFAVIGLLEKSFAALV 560
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLG----SDGLAASVAR 487
D FT+ ME LD IAAG + +L+ +Y G SD A S+AR
Sbjct: 561 DYDFTSSMEDELDEIAAGHENGAHWLTGFYFGDAEASDAKAESIAR 606
[103][TOP]
>UniRef100_B1S7E6 DNA topoisomerase n=1 Tax=Bifidobacterium dentium ATCC 27678
RepID=B1S7E6_9BIFI
Length = 1004
Score = 113 bits (283), Expect = 7e-24
Identities = 67/139 (48%), Positives = 87/139 (62%), Gaps = 2/139 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + PG+ +A + + H T PPARYT+ASLVK LEA +GRPSTYASI+ T++ RGY
Sbjct: 484 LPPMRPGDELAATEVAADGHETQPPARYTEASLVKTLEAKEIGRPSTYASIISTIIDRGY 543
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG +AL P AF V +LL FP +VD FTA+ME LD IA G
Sbjct: 544 VYERG----------RALIPSWLAFSVVKLLETKFPKYVDYQFTADMENGLDQIAHGMET 593
Query: 425 RQEYLSSYYLGS-DGLAAS 478
+++L+S+Y GS +G A S
Sbjct: 594 GKDWLTSFYFGSGEGAAQS 612
[104][TOP]
>UniRef100_UPI00018A01AD hypothetical protein BIFGAL_00149 n=1 Tax=Bifidobacterium gallicum
DSM 20093 RepID=UPI00018A01AD
Length = 991
Score = 113 bits (282), Expect = 9e-24
Identities = 67/139 (48%), Positives = 85/139 (61%), Gaps = 2/139 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + PG+ + + + H T PPARYT+ASLVK LEA +GRPSTYASI+ T++ RGY
Sbjct: 473 LPPMQPGDELNATNVAADGHETQPPARYTEASLVKTLEAKEIGRPSTYASIISTIIDRGY 532
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG +AL P AF V +LL FP +VD FTA+ME LD IA G
Sbjct: 533 VYERG----------RALVPSWLAFAVIKLLETNFPKYVDYQFTADMENGLDEIAHGKET 582
Query: 425 RQEYLSSYYLGS-DGLAAS 478
+E+L+ +Y GS DG A S
Sbjct: 583 GREWLTRFYFGSGDGAAQS 601
[105][TOP]
>UniRef100_Q1IWT9 DNA topoisomerase n=1 Tax=Deinococcus geothermalis DSM 11300
RepID=Q1IWT9_DEIGD
Length = 964
Score = 113 bits (282), Expect = 9e-24
Identities = 66/134 (49%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + GE V ++ H T PPARYT+ASLV+ LEA G+GRPSTYASI+ T+ RGY
Sbjct: 467 LPPLSEGERVTAESVKAESHETQPPARYTEASLVQALEAAGIGRPSTYASILGTIQDRGY 526
Query: 248 -VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +G QAL P TAF LL +F VD FTA ME LD IA G A
Sbjct: 527 AVKKG----------QALVPTWTAFATSALLEHHFGQLVDYDFTARMEEDLDDIAGGRAR 576
Query: 425 RQEYLSSYYLGSDG 466
R YL +YLG G
Sbjct: 577 RVPYLRRFYLGEGG 590
[106][TOP]
>UniRef100_Q8NTJ8 DNA topoisomerase n=1 Tax=Corynebacterium glutamicum
RepID=Q8NTJ8_CORGL
Length = 996
Score = 112 bits (281), Expect = 1e-23
Identities = 70/149 (46%), Positives = 90/149 (60%), Gaps = 5/149 (3%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + V +++ H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+
Sbjct: 480 AEKRLPLLSEGDLLKVLSIEADGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQ 539
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV SRG AL P AF V LL F S VD FT+ ME LD IAA
Sbjct: 540 DRGYVYSRG----------NALVPSWVAFAVVGLLEANFTSLVDYDFTSSMEDELDNIAA 589
Query: 413 GAADRQEYLSSYYLG----SDGLAASVAR 487
G R E+L+ +Y G +A SVAR
Sbjct: 590 GREGRTEWLNGFYFGDAEADQSMAESVAR 618
[107][TOP]
>UniRef100_Q744B6 DNA topoisomerase n=1 Tax=Mycobacterium avium subsp.
paratuberculosis RepID=Q744B6_MYCPA
Length = 932
Score = 112 bits (281), Expect = 1e-23
Identities = 66/150 (44%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + G+ + L H T PP RYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 478 GEADDAESRLPQLTQGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSI 537
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 538 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 588
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIA+G R ++L+++Y G + G+A S+AR
Sbjct: 589 AIASGQERRTDWLNNFYFGGEHGVADSIAR 618
[108][TOP]
>UniRef100_C5CCT9 DNA topoisomerase n=1 Tax=Micrococcus luteus NCTC 2665
RepID=C5CCT9_MICLC
Length = 944
Score = 112 bits (281), Expect = 1e-23
Identities = 67/147 (45%), Positives = 85/147 (57%), Gaps = 1/147 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V GE + ++ H T+PPARYT+AS+V ELE +GRPSTYA + T++ RGY
Sbjct: 493 LPQVAQGERLTGDPIEATGHETSPPARYTEASIVAELERREIGRPSTYAPTISTIMDRGY 552
Query: 248 VS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
VS RGT AL P TAF V LL YF ++VD FTA ME LD IAAG
Sbjct: 553 VSKRGT----------ALVPSWTAFAVIGLLEDYFATYVDYDFTARMEDDLDRIAAGELG 602
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
R+ +L ++Y G A A EK ++
Sbjct: 603 REAWLQTFYFG-----APAAETEKGVE 624
[109][TOP]
>UniRef100_C3PJV8 DNA topoisomerase n=1 Tax=Corynebacterium aurimucosum ATCC 700975
RepID=C3PJV8_CORA7
Length = 972
Score = 112 bits (281), Expect = 1e-23
Identities = 67/145 (46%), Positives = 91/145 (62%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + +A+ H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+ RGY
Sbjct: 464 LPHLNEGDTLKTAAVTADGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQDRGY 523
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V SRG AL P AF V LL F VD FT+ ME LDAIAAG+ +
Sbjct: 524 VLSRG----------NALVPSWVAFAVVGLLENNFTELVDYDFTSSMEDELDAIAAGSEN 573
Query: 425 RQEYLSSYYLGS----DGLAASVAR 487
++L+++Y G+ + AAS+AR
Sbjct: 574 GTDWLNNFYFGNTEAGERKAASIAR 598
[110][TOP]
>UniRef100_A0QA61 DNA topoisomerase n=1 Tax=Mycobacterium avium 104
RepID=A0QA61_MYCA1
Length = 932
Score = 112 bits (281), Expect = 1e-23
Identities = 66/150 (44%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + G+ + L H T PP RYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 478 GEADDAESRLPQLTQGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSI 537
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 538 IKTIQDRGYVHK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 588
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
AIA+G R ++L+++Y G + G+A S+AR
Sbjct: 589 AIASGQERRTDWLNNFYFGGEHGVADSIAR 618
[111][TOP]
>UniRef100_B2GH68 DNA topoisomerase n=1 Tax=Kocuria rhizophila DC2201
RepID=B2GH68_KOCRD
Length = 980
Score = 112 bits (280), Expect = 2e-23
Identities = 63/133 (47%), Positives = 84/133 (63%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + S + HTTTPPARYT+ASLVK L+ LG+GRPSTYA+ + T++ RGY
Sbjct: 496 LPVMAEGDALDASEVTADGHTTTPPARYTEASLVKTLDELGIGRPSTYAATISTIMDRGY 555
Query: 248 VS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG+ AL P AF V +LL +F +VD FTAE+E LD IA G A+
Sbjct: 556 VQVRGS----------ALIPSWLAFSVVRLLEDHFSDYVDYDFTAELEDDLDRIARGEAE 605
Query: 425 RQEYLSSYYLGSD 463
R ++LS +Y G +
Sbjct: 606 RVKWLSGFYFGEN 618
[112][TOP]
>UniRef100_A4QAW2 DNA topoisomerase n=1 Tax=Corynebacterium glutamicum R
RepID=A4QAW2_CORGB
Length = 1004
Score = 112 bits (280), Expect = 2e-23
Identities = 70/149 (46%), Positives = 89/149 (59%), Gaps = 5/149 (3%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + V ++ H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+
Sbjct: 483 AEKRLPLLSEGDLLKVLGIEADGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQ 542
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV SRG AL P AF V LL F S VD FT+ ME LD IAA
Sbjct: 543 DRGYVYSRG----------NALVPSWVAFAVVGLLEANFTSLVDYDFTSSMEDELDNIAA 592
Query: 413 GAADRQEYLSSYYLG----SDGLAASVAR 487
G R E+L+ +Y G +A SVAR
Sbjct: 593 GREGRTEWLNGFYFGDAEADQSMAESVAR 621
[113][TOP]
>UniRef100_C8X984 DNA topoisomerase I n=1 Tax=Nakamurella multipartita DSM 44233
RepID=C8X984_9ACTO
Length = 978
Score = 112 bits (279), Expect = 2e-23
Identities = 66/150 (44%), Positives = 86/150 (57%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + G+ + + L H TTPPARYT+ SL+ L+ LG+GRPSTY SI
Sbjct: 471 GEADDAERRLPKLETGQKLDIRDLIPASHVTTPPARYTEPSLIGALQDLGIGRPSTYTSI 530
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T++ RGYV + QAL P AF V LL ++F VD FTA ME LD
Sbjct: 531 IRTIIDRGYVWK---------KGQALVPSWIAFAVIGLLEQHFSRLVDYNFTAAMEDELD 581
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IA G R ++LS++Y G D G A SV R
Sbjct: 582 GIADGRIGRTDWLSAFYFGGDLGPAGSVGR 611
[114][TOP]
>UniRef100_C1RGM2 DNA topoisomerase n=1 Tax=Cellulomonas flavigena DSM 20109
RepID=C1RGM2_9CELL
Length = 934
Score = 112 bits (279), Expect = 2e-23
Identities = 71/155 (45%), Positives = 88/155 (56%), Gaps = 3/155 (1%)
Frame = +2
Query: 32 ARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTY 211
A G S + LP + G+PV S L H T+PP RYT+ASLVK LE G+GRPSTY
Sbjct: 492 AEGGASGSDDARLPQMAQGDPVTGSDLTADGHRTSPPPRYTEASLVKALEERGIGRPSTY 551
Query: 212 ASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEME 388
A+ + + RGYV +RG QAL P AF V +LL F VD FTA ME
Sbjct: 552 AATIGVIQDRGYVTNRG----------QALVPTWLAFAVTRLLEENFDRLVDYNFTAGME 601
Query: 389 RSLDAIAAGAADRQEYLSSYYLG--SDGLAASVAR 487
SLDAIAAG R ++L+ +Y G SD +A+ R
Sbjct: 602 ESLDAIAAGQKGRVDWLTEFYFGDRSDSVASGGLR 636
[115][TOP]
>UniRef100_C0WHZ9 DNA topoisomerase n=1 Tax=Corynebacterium accolens ATCC 49725
RepID=C0WHZ9_9CORY
Length = 997
Score = 112 bits (279), Expect = 2e-23
Identities = 69/160 (43%), Positives = 90/160 (56%), Gaps = 5/160 (3%)
Frame = +2
Query: 23 AMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRP 202
A A TS + LP + G + + H+T PPARYT+ASLVK++E LG+GRP
Sbjct: 460 AYGADEDTSKKSENRLPHLEQGRDLKAEEVSAEGHSTNPPARYTEASLVKKMEDLGIGRP 519
Query: 203 STYASIVETLVLRGY-VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTA 379
STYASI++T+ RGY VSRG AL P AF V LL F VD FT+
Sbjct: 520 STYASIIKTIQDRGYVVSRG----------NALVPSWVAFAVVGLLEENFTELVDYDFTS 569
Query: 380 EMERSLDAIAAGAADRQEYLSSYYLG----SDGLAASVAR 487
ME LD+IA G D ++L+ +Y G ++ AAS+AR
Sbjct: 570 SMEDELDSIATGTEDGTDWLNGFYFGNAEANEHKAASIAR 609
[116][TOP]
>UniRef100_C2CTL2 DNA topoisomerase n=1 Tax=Gardnerella vaginalis ATCC 14019
RepID=C2CTL2_GARVA
Length = 952
Score = 111 bits (278), Expect = 3e-23
Identities = 66/154 (42%), Positives = 90/154 (58%), Gaps = 5/154 (3%)
Frame = +2
Query: 59 AQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVL 238
++ LP + G+ + + H T PPARYT+ASLVK LEA +GRPSTYASI+ T++
Sbjct: 460 SKALPPMANGDVLKALRVSADGHETQPPARYTEASLVKTLEAKEIGRPSTYASIISTIID 519
Query: 239 RGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAG 415
RGYV RG +AL P AF V +LL FP++VD AFTA+ME LD IA G
Sbjct: 520 RGYVYERG----------RALIPSWLAFAVIKLLESNFPTYVDYAFTADMENGLDRIAHG 569
Query: 416 AADRQEYLSSYYLGSDGLAASVARM----EKEID 505
+++L +Y G +G A M +K++D
Sbjct: 570 EEAGKDWLYKFYFGDNGAVAGDFAMHEGLQKQVD 603
[117][TOP]
>UniRef100_C0UB95 Topoisomerase IA n=1 Tax=Geodermatophilus obscurus DSM 43160
RepID=C0UB95_9ACTO
Length = 593
Score = 111 bits (278), Expect = 3e-23
Identities = 62/140 (44%), Positives = 83/140 (59%)
Frame = +2
Query: 47 STTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVE 226
S A + LP V G+ + L+ H+TTPP+RYT+ SLV LE LG+GRPSTYASI++
Sbjct: 143 SDDAERRLPRVERGQQLDTRELEAKGHSTTPPSRYTEPSLVARLEELGIGRPSTYASIMQ 202
Query: 227 TLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAI 406
T+ RGYV + AL P AF V LL ++F VD FTA +E+ LD I
Sbjct: 203 TIQDRGYVWK---------KGSALVPTFVAFAVINLLEQHFAQLVDYDFTASLEQELDEI 253
Query: 407 AAGAADRQEYLSSYYLGSDG 466
AAG R ++L+ +Y G +G
Sbjct: 254 AAGDLGRVDWLTEFYFGGEG 273
[118][TOP]
>UniRef100_UPI000185C20D putative DNA topoisomerase I n=1 Tax=Corynebacterium amycolatum
SK46 RepID=UPI000185C20D
Length = 1036
Score = 111 bits (277), Expect = 4e-23
Identities = 65/154 (42%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A V SA+S + A + LP + G+ + + H+T PPAR+T+ASLVK++E
Sbjct: 504 AYVEVSALSDGRKVADNAEKRLPQLTEGQGLTATDFSADSHSTNPPARFTEASLVKKMED 563
Query: 185 LGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYASI++T+ RGYV SRG AL P AF V L+ F V
Sbjct: 564 LGIGRPSTYASIIKTIQDRGYVYSRG----------NALVPSWVAFAVVGLMEEAFSDLV 613
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSD 463
+ FT+E+E LD IAAG DR +L+ +Y G +
Sbjct: 614 NYDFTSELEDELDGIAAGNKDRTTWLTGFYFGDE 647
[119][TOP]
>UniRef100_A0ZZQ9 DNA topoisomerase n=1 Tax=Bifidobacterium adolescentis ATCC 15703
RepID=A0ZZQ9_BIFAA
Length = 1027
Score = 111 bits (277), Expect = 4e-23
Identities = 69/152 (45%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPST 208
SA+ T LP + PG+ +A + H T PPARYT+ASLVK LE +GRPST
Sbjct: 485 SAKASKKTDDNVSLPPMQPGDELAAVDVAADGHETQPPARYTEASLVKTLEQKEIGRPST 544
Query: 209 YASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEM 385
YASI+ T++ RGYV RG +AL P AF V +LL FP +VD FTA+M
Sbjct: 545 YASIISTIIDRGYVYERG----------RALIPSWLAFSVTKLLETKFPKYVDYEFTADM 594
Query: 386 ERSLDAIAAGAADRQEYLSSYYLGS-DGLAAS 478
E LD IA G + +L+ +Y GS DG A S
Sbjct: 595 ETGLDQIAGGHETGKAWLTRFYFGSGDGAAQS 626
[120][TOP]
>UniRef100_C2GG61 DNA topoisomerase n=1 Tax=Corynebacterium glucuronolyticum ATCC
51866 RepID=C2GG61_9CORY
Length = 958
Score = 111 bits (277), Expect = 4e-23
Identities = 67/152 (44%), Positives = 88/152 (57%), Gaps = 1/152 (0%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A V +S +S + A LP + G+ V H+T PPARYT+ASLVK++E
Sbjct: 444 AYVETSELSDGRKVADNAESHLPVLTEGQTVHAEDATPEGHSTNPPARYTEASLVKKMED 503
Query: 185 LGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYASI++T+ RGYV SRG AL P AF V L+ + F S V
Sbjct: 504 LGIGRPSTYASIIKTIQDRGYVFSRG----------NALVPSWVAFAVVGLMEQNFGSLV 553
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLG 457
D FT+E+E LD+IA G DR +L+ +Y G
Sbjct: 554 DYDFTSELEDQLDSIATGNTDRTNWLTGFYFG 585
[121][TOP]
>UniRef100_C0VRF5 DNA topoisomerase n=1 Tax=Corynebacterium glucuronolyticum ATCC
51867 RepID=C0VRF5_9CORY
Length = 958
Score = 111 bits (277), Expect = 4e-23
Identities = 67/152 (44%), Positives = 88/152 (57%), Gaps = 1/152 (0%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A V +S +S + A LP + G+ V H+T PPARYT+ASLVK++E
Sbjct: 444 AYVETSELSDGRKVADNAESHLPVLTEGQTVHAEDATPEGHSTNPPARYTEASLVKKMED 503
Query: 185 LGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYASI++T+ RGYV SRG AL P AF V L+ + F S V
Sbjct: 504 LGIGRPSTYASIIKTIQDRGYVFSRG----------NALVPSWVAFAVVGLMEQNFGSLV 553
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLG 457
D FT+E+E LD+IA G DR +L+ +Y G
Sbjct: 554 DYDFTSELEDQLDSIATGNTDRTNWLTGFYFG 585
[122][TOP]
>UniRef100_Q9RUL0 DNA topoisomerase n=1 Tax=Deinococcus radiodurans
RepID=Q9RUL0_DEIRA
Length = 1021
Score = 110 bits (276), Expect = 5e-23
Identities = 67/151 (44%), Positives = 84/151 (55%), Gaps = 5/151 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ V + +H T PPARYT+ASLV+ LE G+GRPSTYASI+ T+ RGY
Sbjct: 519 LPPLKXGDAVRAQDVKAEDHETQPPARYTEASLVQALEGAGIGRPSTYASILGTIQDRGY 578
Query: 248 -VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
+ +GT AL P TAF LL +F + VD FTA+ME LD IA G
Sbjct: 579 ALKKGT----------ALVPSWTAFATSALLEHHFGTLVDYDFTAKMEEDLDEIAGGREH 628
Query: 425 RQEYLSSYYLGSDG----LAASVARMEKEID 505
R YL +YLG +G L + R EID
Sbjct: 629 RVPYLRRFYLGEEGEGMALKPLIERQMGEID 659
[123][TOP]
>UniRef100_C0VAV7 DNA topoisomerase n=1 Tax=Xylanimonas cellulosilytica DSM 15894
RepID=C0VAV7_9MICO
Length = 924
Score = 110 bits (276), Expect = 5e-23
Identities = 64/136 (47%), Positives = 79/136 (58%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + L H+TTPPARYT+ASLVK LE LG+GRPSTYA+ + T+ RGY
Sbjct: 479 LPRMAQGDGLDARDLTADGHSTTPPARYTEASLVKALEELGIGRPSTYAATISTIQDRGY 538
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R QA+ P AF V +LL +F S VD FTAEME+ LD IA G R
Sbjct: 539 V---------RTSGQAMIPTWLAFAVTKLLEDHFGSLVDYRFTAEMEQDLDEIAEGRRAR 589
Query: 428 QEYLSSYYLGSDGLAA 475
+L +Y G AA
Sbjct: 590 GAWLEEFYFGDREAAA 605
[124][TOP]
>UniRef100_C0BR25 DNA topoisomerase n=1 Tax=Bifidobacterium pseudocatenulatum DSM
20438 RepID=C0BR25_9BIFI
Length = 1018
Score = 110 bits (276), Expect = 5e-23
Identities = 66/140 (47%), Positives = 84/140 (60%), Gaps = 1/140 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + PG+ +A A+ H T PPARYT+ASLVK LE +GRPSTYASI+ T++ RGY
Sbjct: 496 LPPMNPGDALAAVAVGADGHETQPPARYTEASLVKTLEQKEIGRPSTYASIISTIIDRGY 555
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG +AL P AF V +LL FP +VD FTA+ME LD IA+G
Sbjct: 556 VYERG----------RALIPSWLAFSVVKLLETKFPRYVDYEFTADMESGLDQIASGQET 605
Query: 425 RQEYLSSYYLGSDGLAASVA 484
+ +L+ +Y GS AA A
Sbjct: 606 GRNWLTRFYFGSGEGAAQSA 625
[125][TOP]
>UniRef100_A7BBF8 DNA topoisomerase n=1 Tax=Actinomyces odontolyticus ATCC 17982
RepID=A7BBF8_9ACTO
Length = 914
Score = 110 bits (276), Expect = 5e-23
Identities = 67/157 (42%), Positives = 89/157 (56%), Gaps = 7/157 (4%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LPDV G+P ++ H T PP RYT+A+LVK +E LG+GRPSTYA+ ++T+
Sbjct: 470 AEKTLPDVAEGDPATLTEATPDGHETQPPGRYTEATLVKTMEELGIGRPSTYAATIQTIG 529
Query: 236 LRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV+ RG Q L P AF V +LL + VD FTA ME LD IAA
Sbjct: 530 DRGYVTHRG----------QYLVPTWLAFSVTRLLEENLANLVDYDFTASMEGDLDRIAA 579
Query: 413 GAADRQEYLSSYYLGSD------GLAASVARMEKEID 505
G + E+L+S++ G D GL VA + +ID
Sbjct: 580 GEENGTEFLTSFFFGPDGTGENGGLRHDVASLGDDID 616
[126][TOP]
>UniRef100_B1X5D7 DNA topoisomerase n=1 Tax=Paulinella chromatophora
RepID=B1X5D7_PAUCH
Length = 900
Score = 110 bits (276), Expect = 5e-23
Identities = 64/152 (42%), Positives = 85/152 (55%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP + G+ + L + H T PP+RY++A+LVK LE G+GRPSTYASI+ T++ RG
Sbjct: 458 LLPALKIGDKPKLEQLYALTHETQPPSRYSEAALVKILEKEGIGRPSTYASIIGTIMDRG 517
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y L L P TAF V LL FP VD FTA+ME +LD I+ G +
Sbjct: 518 YAI---------LKNNVLIPSFTAFAVTALLENNFPDLVDIGFTAKMEDTLDEISTGKVE 568
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEIDTAWAR 520
YL+ +Y G GL V R+E ID +R
Sbjct: 569 WLPYLNMFYRGDHGLEEQVQRIEGYIDPGASR 600
[127][TOP]
>UniRef100_A4XC00 DNA topoisomerase n=1 Tax=Salinispora tropica CNB-440
RepID=A4XC00_SALTO
Length = 943
Score = 110 bits (275), Expect = 6e-23
Identities = 60/134 (44%), Positives = 81/134 (60%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP +V +P+ L H T PPARYT+ASLVK LE LG+GRPSTYASI++T+
Sbjct: 472 AERRLPHLVKDQPLTGEQLAAQGHHTQPPARYTEASLVKALEELGIGRPSTYASIMQTIQ 531
Query: 236 LRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAG 415
RGYV++ QA+ P AF V L+ R++P +D FTA ME LD IA G
Sbjct: 532 DRGYVAK---------RGQAMIPSFLAFAVVGLMERHYPRLIDYGFTASMENELDEIAGG 582
Query: 416 AADRQEYLSSYYLG 457
++L+++Y G
Sbjct: 583 DHAAVDFLTAFYFG 596
[128][TOP]
>UniRef100_C2CR83 DNA topoisomerase n=1 Tax=Corynebacterium striatum ATCC 6940
RepID=C2CR83_CORST
Length = 980
Score = 110 bits (275), Expect = 6e-23
Identities = 66/145 (45%), Positives = 88/145 (60%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ +A + + H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+ RGY
Sbjct: 470 LPHLDEGDDLAATKVTADGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQDRGY 529
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V SRG AL P AF V L+ F VD FT+ ME LDAIAAG +
Sbjct: 530 VLSRG----------NALVPSWVAFAVIGLMENNFTELVDYDFTSSMEDELDAIAAGTEN 579
Query: 425 RQEYLSSYYLGS----DGLAASVAR 487
++L+ +Y G+ D A S+AR
Sbjct: 580 GTDWLNGFYFGNAAAKDQKADSIAR 604
[129][TOP]
>UniRef100_O69548 DNA topoisomerase 1 n=2 Tax=Mycobacterium leprae RepID=TOP1_MYCLE
Length = 947
Score = 110 bits (275), Expect = 6e-23
Identities = 66/150 (44%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A + LP + G+ + V L H T PPARYT+ASLVK LE LG+GRPSTY+SI
Sbjct: 479 GEADDAERRLPHLTSGQLLDVIDLTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSI 538
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
++T+ RGYV + AL P AF V LL ++F VD FTA ME LD
Sbjct: 539 IKTVQDRGYVQK---------KGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELD 589
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IA G R +L+++Y G + G++ S+AR
Sbjct: 590 EIANGNEQRTNWLNNFYFGGNHGVSDSIAR 619
[130][TOP]
>UniRef100_B1VI08 DNA topoisomerase n=1 Tax=Corynebacterium urealyticum DSM 7109
RepID=B1VI08_CORU7
Length = 977
Score = 110 bits (274), Expect = 8e-23
Identities = 76/181 (41%), Positives = 97/181 (53%), Gaps = 7/181 (3%)
Frame = +2
Query: 5 APVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEA 184
A V S + + A + LP V G + + HTTTPPARYT+ASLV+++E
Sbjct: 458 AYVEVSRTAEGKDVADNAEKRLPQVTEGVFLTAEDVTADGHTTTPPARYTEASLVRKMEE 517
Query: 185 LGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFV 361
LG+GRPSTYASI+ T+ RGYV RG AL P AF V LL + F + V
Sbjct: 518 LGIGRPSTYASIIRTIQDRGYVLPRG----------NALVPSWVAFAVVGLLEQNFGALV 567
Query: 362 DAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSD------GLAASVARMEKEIDTAWARR 523
D FT+ ME LDAIA G DR ++L +Y G GL VA+ + ID ARR
Sbjct: 568 DYDFTSAMEDQLDAIAEGNEDRTKWLEGFYFGGGTSSQNYGLKNVVAQNLESID---ARR 624
Query: 524 L 526
+
Sbjct: 625 V 625
[131][TOP]
>UniRef100_A8M5X0 DNA topoisomerase n=1 Tax=Salinispora arenicola CNS-205
RepID=A8M5X0_SALAI
Length = 949
Score = 110 bits (274), Expect = 8e-23
Identities = 62/136 (45%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP +V +P+ L H T PPARYT+ASLVK LE LG+GRPSTYASI++T+
Sbjct: 472 AERRLPTLVKDQPLTGEQLVAQGHHTQPPARYTEASLVKALEELGIGRPSTYASIMQTIQ 531
Query: 236 LRGY-VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGY V RG QA+ P AF V L+ R++P +D FTA ME LD IA
Sbjct: 532 DRGYVVKRG----------QAMIPSFLAFAVVGLMERHYPRLIDYGFTASMENELDEIAG 581
Query: 413 GAADRQEYLSSYYLGS 460
G ++L+++Y G+
Sbjct: 582 GDHAAVDFLTAFYFGT 597
[132][TOP]
>UniRef100_A1SDN6 DNA topoisomerase n=1 Tax=Nocardioides sp. JS614 RepID=A1SDN6_NOCSJ
Length = 905
Score = 110 bits (274), Expect = 8e-23
Identities = 64/135 (47%), Positives = 82/135 (60%), Gaps = 1/135 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LPD+ G+ V+ ++L H T PPARYT+A+L+KELE +GRPSTYASI+ T++ RGY
Sbjct: 468 LPDLHEGDAVSAASLAANGHETKPPARYTEATLIKELEDREIGRPSTYASIIGTILNRGY 527
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P AF V +LL +FP V FTA ME LD IA G D
Sbjct: 528 VYKKGT----------ALVPAWLAFSVTRLLEEHFPRQVSYEFTAGMEDVLDEIAGGRKD 577
Query: 425 RQEYLSSYYLGSDGL 469
+ LS +Y GSD +
Sbjct: 578 LKSELSEFYYGSDSV 592
[133][TOP]
>UniRef100_C8NXE9 DNA topoisomerase n=1 Tax=Corynebacterium genitalium ATCC 33030
RepID=C8NXE9_9CORY
Length = 988
Score = 110 bits (274), Expect = 8e-23
Identities = 67/158 (42%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
Frame = +2
Query: 26 MSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPS 205
+ A T + LP + G+ + + H+T PPARYT+ASLVK++E LG+GRPS
Sbjct: 469 LRAYADTQDNKEKHLPQLSEGDALTAREVTADGHSTNPPARYTEASLVKKMEDLGIGRPS 528
Query: 206 TYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEM 385
TYASI++T+ RGYV+ T G AL P AF V L+ + F + VD FT+ M
Sbjct: 529 TYASIIKTIQDRGYVA-----TRG----NALVPTWVAFSVVGLMEQNFDALVDYEFTSSM 579
Query: 386 ERSLDAIAAGAADRQEYLSSYYLG----SDGLAASVAR 487
E LD IA G +R E+L+ +Y G SD A +VAR
Sbjct: 580 EDELDEIAQGTENRTEWLTGFYFGDAEASDTTAEAVAR 617
[134][TOP]
>UniRef100_C6WFC8 DNA topoisomerase n=1 Tax=Actinosynnema mirum DSM 43827
RepID=C6WFC8_ACTMD
Length = 923
Score = 110 bits (274), Expect = 8e-23
Identities = 63/150 (42%), Positives = 86/150 (57%), Gaps = 1/150 (0%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP +V +PV+ + L H+T+PP R+T+ SL+K +E LG+GRPSTYASI
Sbjct: 477 GNADDAESRLPQLVAEQPVSAAELSADGHSTSPPPRFTEPSLIKTMEDLGIGRPSTYASI 536
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGYV + AL P AF V LL ++F VD FTA +E LD
Sbjct: 537 ISTIQDRGYVWK---------KGSALVPSWVAFAVVGLLEQHFGRLVDYDFTAALEDELD 587
Query: 401 AIAAGAADRQEYLSSYYLGSD-GLAASVAR 487
IA G +R +LS +Y G D G +S+ R
Sbjct: 588 GIAEGRQERTTWLSGFYFGGDVGPESSIGR 617
[135][TOP]
>UniRef100_C4FH65 DNA topoisomerase n=1 Tax=Bifidobacterium angulatum DSM 20098
RepID=C4FH65_9BIFI
Length = 996
Score = 110 bits (274), Expect = 8e-23
Identities = 66/157 (42%), Positives = 88/157 (56%), Gaps = 1/157 (0%)
Frame = +2
Query: 17 SSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVG 196
++ R G + LP + G+ + V+ + H T PPARYT+ASLVK LEA +G
Sbjct: 461 AAKQGGRKGENAEGNASLPPMSAGQRLDVADVQADGHETQPPARYTEASLVKTLEAKEIG 520
Query: 197 RPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAF 373
RPSTYASI+ T++ RGYV RG +AL P AF V +LL FP VD F
Sbjct: 521 RPSTYASIISTIIDRGYVYERG----------RALIPSWLAFAVVKLLETKFPKLVDYQF 570
Query: 374 TAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAASVA 484
TA+ME LD IA G +++L+ +Y G AA+ A
Sbjct: 571 TADMENGLDQIAHGKQTGRDWLTRFYFGDGDAAAANA 607
[136][TOP]
>UniRef100_B9AX52 DNA topoisomerase n=1 Tax=Bifidobacterium breve DSM 20213
RepID=B9AX52_BIFBR
Length = 1016
Score = 110 bits (274), Expect = 8e-23
Identities = 68/159 (42%), Positives = 89/159 (55%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELE 181
+A S A ++ + LP + G+ V S ++ H T PPARYT+A+LVK LE
Sbjct: 467 AAAADKSGAKATKSDASESNASLPPMEVGQRVEASDIEPDGHETQPPARYTEATLVKTLE 526
Query: 182 ALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSF 358
A +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL FP
Sbjct: 527 AKEIGRPSTYASIISTIMDRGYVYERG----------RALIPSWLAFSVTKLLETNFPKL 576
Query: 359 VDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAA 475
VD FTAEME LD IA G +++L+ +Y GS AA
Sbjct: 577 VDYTFTAEMENGLDRIAHGEETGRDWLTHFYFGSGEGAA 615
[137][TOP]
>UniRef100_B6XWS1 DNA topoisomerase n=1 Tax=Bifidobacterium catenulatum DSM 16992
RepID=B6XWS1_9BIFI
Length = 1018
Score = 110 bits (274), Expect = 8e-23
Identities = 66/139 (47%), Positives = 85/139 (61%), Gaps = 2/139 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + PG+ +A A+ H T PPARYT+ASLVK LE +GRPSTYASI+ T++ RGY
Sbjct: 496 LPPMNPGDALAAVAVGADGHETQPPARYTEASLVKTLEQKEIGRPSTYASIISTIIDRGY 555
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG +AL P AF V +LL FP +VD FTA+ME LD IA+G
Sbjct: 556 VYERG----------RALIPSWLAFSVVKLLETKFPRYVDYEFTADMESGLDQIASGQET 605
Query: 425 RQEYLSSYYLGS-DGLAAS 478
+ +L+ +Y GS +G A S
Sbjct: 606 GRNWLTRFYFGSGEGSAQS 624
[138][TOP]
>UniRef100_Q8G6Z5 DNA topoisomerase n=2 Tax=Bifidobacterium longum RepID=Q8G6Z5_BIFLO
Length = 1030
Score = 109 bits (273), Expect = 1e-22
Identities = 68/159 (42%), Positives = 90/159 (56%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELE 181
+A + A G ++ + LP + G+ V S ++ H T PPARYT+A+LVK LE
Sbjct: 476 AAAAGKTDAKAVRGDASESNTSLPPMSVGQQVEASDIEPDGHETQPPARYTEATLVKTLE 535
Query: 182 ALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSF 358
A +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL FP
Sbjct: 536 AKEIGRPSTYASIISTIMDRGYVYERG----------RALIPSWLAFSVTKLLETNFPKL 585
Query: 359 VDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAA 475
VD FTAEME LD IA G +++L+ +Y GS AA
Sbjct: 586 VDYQFTAEMENGLDRIAHGEESGRDWLTHFYFGSGEGAA 624
[139][TOP]
>UniRef100_B3DUA2 DNA topoisomerase n=1 Tax=Bifidobacterium longum DJO10A
RepID=B3DUA2_BIFLD
Length = 1028
Score = 109 bits (273), Expect = 1e-22
Identities = 68/159 (42%), Positives = 90/159 (56%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELE 181
+A + A G ++ + LP + G+ V S ++ H T PPARYT+A+LVK LE
Sbjct: 474 AAAAGKTDAKAVRGDASESNTSLPPMSVGQQVEASDIEPDGHETQPPARYTEATLVKTLE 533
Query: 182 ALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSF 358
A +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL FP
Sbjct: 534 AKEIGRPSTYASIISTIMDRGYVYERG----------RALIPSWLAFSVTKLLETNFPKL 583
Query: 359 VDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAA 475
VD FTAEME LD IA G +++L+ +Y GS AA
Sbjct: 584 VDYQFTAEMENGLDRIAHGEESGRDWLTHFYFGSGEGAA 622
[140][TOP]
>UniRef100_C2GSS0 DNA topoisomerase n=1 Tax=Bifidobacterium longum subsp. infantis
ATCC 55813 RepID=C2GSS0_BIFLO
Length = 1028
Score = 109 bits (273), Expect = 1e-22
Identities = 68/159 (42%), Positives = 90/159 (56%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELE 181
+A + A G ++ + LP + G+ V S ++ H T PPARYT+A+LVK LE
Sbjct: 474 AAAAGKTDAKAVRGDASESNTSLPPMSVGQQVEASDIEPDGHETQPPARYTEATLVKTLE 533
Query: 182 ALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSF 358
A +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL FP
Sbjct: 534 AKEIGRPSTYASIISTIMDRGYVYERG----------RALIPSWLAFSVTKLLETNFPKL 583
Query: 359 VDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAA 475
VD FTAEME LD IA G +++L+ +Y GS AA
Sbjct: 584 VDYQFTAEMENGLDRIAHGEESGRDWLTHFYFGSGEGAA 622
[141][TOP]
>UniRef100_A7A3H3 DNA topoisomerase n=1 Tax=Bifidobacterium adolescentis L2-32
RepID=A7A3H3_BIFAD
Length = 1025
Score = 109 bits (273), Expect = 1e-22
Identities = 66/139 (47%), Positives = 83/139 (59%), Gaps = 2/139 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + PG+ +A + H T PPARYT+ASLVK LE +GRPSTYASI+ T++ RGY
Sbjct: 496 LPPMQPGDELAAVDVAADGHETQPPARYTEASLVKTLEQKEIGRPSTYASIISTIIDRGY 555
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V RG +AL P AF V +LL FP +VD FTA+ME LD IA G
Sbjct: 556 VYERG----------RALIPSWLAFSVTKLLETKFPKYVDYEFTADMETGLDQIAGGHET 605
Query: 425 RQEYLSSYYLGS-DGLAAS 478
+ +L+ +Y GS DG A S
Sbjct: 606 GKAWLTRFYFGSGDGAAQS 624
[142][TOP]
>UniRef100_UPI0001B56EBB DNA topoisomerase I n=1 Tax=Streptomyces sp. SPB78
RepID=UPI0001B56EBB
Length = 957
Score = 109 bits (272), Expect = 1e-22
Identities = 66/143 (46%), Positives = 81/143 (56%), Gaps = 4/143 (2%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+P++ L H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 476 LPQVAEGDPLSAEELTADGHATKPPARYTEASLVKELEEREIGRPSTYASILGTILDRGY 535
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL R+F VD FTA+ME LD IA G A
Sbjct: 536 VFKKGT----------ALVPSFLSFAVVNLLERHFGRLVDYDFTAKMEDDLDRIARGEAQ 585
Query: 425 RQEYLSSYYLG---SDGLAASVA 484
+L +Y G DG + A
Sbjct: 586 AVPWLRRFYFGEGDGDGAGSGAA 608
[143][TOP]
>UniRef100_B7GT79 DNA topoisomerase n=1 Tax=Bifidobacterium longum subsp. infantis
ATCC 15697 RepID=B7GT79_BIFLI
Length = 1027
Score = 109 bits (272), Expect = 1e-22
Identities = 68/159 (42%), Positives = 90/159 (56%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELE 181
+A + A G ++ + LP + G+ V S ++ H T PPARYT+A+LVK LE
Sbjct: 474 TAAAGKTDAKAVRGDASESNTSLPPMSVGQQVEASDVEPDGHETQPPARYTEATLVKTLE 533
Query: 182 ALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSF 358
A +GRPSTYASI+ T++ RGYV RG +AL P AF V +LL FP
Sbjct: 534 AKEIGRPSTYASIISTIMDRGYVYERG----------RALIPSWLAFSVTKLLETNFPKL 583
Query: 359 VDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAA 475
VD FTAEME LD IA G +++L+ +Y GS AA
Sbjct: 584 VDYQFTAEMENGLDRIAHGEESGRDWLTHFYFGSGEGAA 622
[144][TOP]
>UniRef100_C2BTY7 DNA topoisomerase n=1 Tax=Mobiluncus curtisii ATCC 43063
RepID=C2BTY7_9ACTO
Length = 913
Score = 109 bits (272), Expect = 1e-22
Identities = 73/172 (42%), Positives = 93/172 (54%), Gaps = 11/172 (6%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVE---HTTTPPARYTDASLVKELEALGVGR 199
+A PG T LP + + + + LD E H TTPPARYTDASLVK +E +GR
Sbjct: 467 AATPGGGKTGEARLPRMQAADRLQLDHLDSGEDRQHFTTPPARYTDASLVKAMEEREIGR 526
Query: 200 PSTYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTA 379
PSTYAS + T+V R YV R QAL P AF V +LL P +D FTA
Sbjct: 527 PSTYASTISTIVDRQYVYR---------RGQALVPSWLAFSVVKLLEENLPGLIDYDFTA 577
Query: 380 EMERSLDAIAAGAADRQEYLSSYYLGSD--------GLAASVARMEKEIDTA 511
+ME LD IAAG ADR ++L +++ G GL +VA + +ID A
Sbjct: 578 DMEADLDKIAAGKADRTQWLKNFWYGQGKGSDLQGLGLQRAVAEL-GDIDAA 628
[145][TOP]
>UniRef100_C1YIL0 DNA topoisomerase n=1 Tax=Nocardiopsis dassonvillei subsp.
dassonvillei DSM 43111 RepID=C1YIL0_NOCDA
Length = 946
Score = 109 bits (272), Expect = 1e-22
Identities = 62/133 (46%), Positives = 81/133 (60%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+P+ L+ H+T PPARYT+A+LVKELE +GRPSTYASI+ T++ RGY
Sbjct: 490 LPAMSEGDPLKAQNLEAEGHSTRPPARYTEATLVKELEEREIGRPSTYASIIGTILDRGY 549
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P AF V QLL R+F + VD FTA +E LD IA G A+
Sbjct: 550 VFKKGT----------ALVPSFLAFAVVQLLERHFGNLVDYEFTARLEDVLDDIARGEAE 599
Query: 425 RQEYLSSYYLGSD 463
+L +Y G +
Sbjct: 600 SLPWLRRFYFGGE 612
[146][TOP]
>UniRef100_C0W269 DNA topoisomerase n=1 Tax=Actinomyces coleocanis DSM 15436
RepID=C0W269_9ACTO
Length = 924
Score = 109 bits (272), Expect = 1e-22
Identities = 64/140 (45%), Positives = 80/140 (57%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
Q LP +V G+ + V+ H TTPP RYT+ASLVK +E G+GRPSTYA+ + +V R
Sbjct: 483 QRLPKLVQGDVLDVTGAQASGHQTTPPPRYTEASLVKAMEDRGIGRPSTYAATISVIVDR 542
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
GYV++ QAL P AF V +LL VD FTA ME LD IA G A
Sbjct: 543 GYVNK---------RGQALVPTWLAFSVVRLLEENLGRLVDYDFTATMEADLDRIATGEA 593
Query: 422 DRQEYLSSYYLGSDGLAASV 481
DR ++L S+YLG A V
Sbjct: 594 DRVKWLQSFYLGEGNAAPLV 613
[147][TOP]
>UniRef100_B5G9K7 DNA topoisomerase n=1 Tax=Streptomyces sp. SPB74 RepID=B5G9K7_9ACTO
Length = 962
Score = 109 bits (272), Expect = 1e-22
Identities = 66/141 (46%), Positives = 80/141 (56%), Gaps = 2/141 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+P++ L H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 476 LPQVAEGDPLSAEELTADGHATKPPARYTEASLVKELEEREIGRPSTYASILGTILDRGY 535
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL R+F VD FTA+ME LD IA G A
Sbjct: 536 VFKKGT----------ALVPSFLSFAVVNLLERHFGRLVDYDFTAKMEDDLDRIARGEAQ 585
Query: 425 RQEYLSSYYLG-SDGLAASVA 484
+L +Y G DG A
Sbjct: 586 AVPWLRRFYFGEGDGAGEGAA 606
[148][TOP]
>UniRef100_A1HN51 DNA topoisomerase n=1 Tax=Thermosinus carboxydivorans Nor1
RepID=A1HN51_9FIRM
Length = 711
Score = 109 bits (272), Expect = 1e-22
Identities = 61/145 (42%), Positives = 86/145 (59%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP+++ G+ + ++ + +H T PP RYT+ASLVK LE G+GRPSTYA I++T++ RGY
Sbjct: 434 LPELMAGQTLKLAKIVPKQHFTQPPPRYTEASLVKTLEEKGIGRPSTYAPIIQTIIERGY 493
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R ++ P FVV LL+R+FP VD FTA ME LD IA G
Sbjct: 494 VQRVDKK---------FQPTELGFVVVDLLKRHFPDIVDVEFTASMEDRLDDIAEGEISH 544
Query: 428 QEYLSSYYLGSDGLAASVARMEKEI 502
E L ++Y A ++++ EKEI
Sbjct: 545 VEVLRNFY---QPFAETLSKAEKEI 566
[149][TOP]
>UniRef100_UPI000050FDAA COG0550: Topoisomerase IA n=1 Tax=Brevibacterium linens BL2
RepID=UPI000050FDAA
Length = 946
Score = 108 bits (271), Expect = 2e-22
Identities = 61/131 (46%), Positives = 80/131 (61%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++V + HTT PP R+T+ASLVK+LE LG+GRPSTYA+ + + RGY
Sbjct: 474 LPQVDEGQSLSVVKAEADGHTTAPPPRFTEASLVKQLEELGIGRPSTYAATISVIQDRGY 533
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V SRG AL P AF V +LL +F VD AFTA++E LD IA G D
Sbjct: 534 VTSRG----------NALVPSWLAFSVVRLLEEHFTGLVDYAFTADLESELDRIAMGEED 583
Query: 425 RQEYLSSYYLG 457
R+ +L+ +Y G
Sbjct: 584 RKAWLARFYFG 594
[150][TOP]
>UniRef100_C4E3I5 DNA topoisomerase n=1 Tax=Streptosporangium roseum DSM 43021
RepID=C4E3I5_STRRS
Length = 883
Score = 108 bits (271), Expect = 2e-22
Identities = 61/134 (45%), Positives = 83/134 (61%), Gaps = 1/134 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP++ G+ + + L+++ H T PPARYT+ASL+KELE +GRPSTYASI+ T++ RGY
Sbjct: 474 LPNLDEGDRLTAAELNVLSHATKPPARYTEASLIKELEDREIGRPSTYASIIGTILDRGY 533
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P AF V LL ++F VD FTA+ME+ LD IA A+
Sbjct: 534 VFKKGT----------ALVPSFLAFAVVNLLEQHFGHLVDYDFTADMEKVLDDIANDRAE 583
Query: 425 RQEYLSSYYLGSDG 466
R L +Y G +G
Sbjct: 584 RVPELRRFYFGEEG 597
[151][TOP]
>UniRef100_A6Q5J8 DNA topoisomerase n=1 Tax=Nitratiruptor sp. SB155-2
RepID=A6Q5J8_NITSB
Length = 732
Score = 108 bits (270), Expect = 2e-22
Identities = 59/147 (40%), Positives = 88/147 (59%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LPD+ GE ++ ++ +H T PPARYT+ASL+K LE+LG+GRPSTYA + L R
Sbjct: 426 KLLPDLKEGEEAKLTKIEANQHFTEPPARYTEASLIKMLESLGIGRPSTYAPTIALLQAR 485
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
Y+ L +A+ P AF V ++L ++FP VD++FTA+ME LD IA
Sbjct: 486 NYI---------ELEKRAIKPTEIAFKVIEVLEKHFPEIVDSSFTAKMEEELDEIAEAKK 536
Query: 422 DRQEYLSSYYLGSDGLAASVARMEKEI 502
D Q+ L ++Y D + + +KEI
Sbjct: 537 DWQKVLKAFY---DPFIELIEKGKKEI 560
[152][TOP]
>UniRef100_C9KBC9 DNA topoisomerase I n=1 Tax=Sanguibacter keddieii DSM 10542
RepID=C9KBC9_9MICO
Length = 962
Score = 108 bits (270), Expect = 2e-22
Identities = 62/133 (46%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + L H+T+ P R+T+ASLVK LE G+GRPSTYAS + T+ RGY
Sbjct: 494 LPQMAEGDAMTSRELSADGHSTSAPPRFTEASLVKALEERGIGRPSTYASTISTIQDRGY 553
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V SRG QAL P AF V +LL +F +D FTAEME LDAIAAG +
Sbjct: 554 VLSRG----------QALVPSWLAFAVIRLLEEHFGQLIDYDFTAEMEADLDAIAAGDKE 603
Query: 425 RQEYLSSYYLGSD 463
R +L+ +Y G D
Sbjct: 604 RVAWLTQFYFGDD 616
[153][TOP]
>UniRef100_C2A9C7 DNA topoisomerase n=1 Tax=Thermomonospora curvata DSM 43183
RepID=C2A9C7_THECU
Length = 899
Score = 108 bits (270), Expect = 2e-22
Identities = 64/147 (43%), Positives = 83/147 (56%), Gaps = 1/147 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+P++ L H+T PPARYT+A+LVKELE +GRPSTYA+I+ T++ RGY
Sbjct: 463 LPALAEGDPLSAERLQAQGHSTRPPARYTEATLVKELEEREIGRPSTYATILGTILERGY 522
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P AF V LL ++F VD FTA+ME LD IA G A+
Sbjct: 523 VFKKGT----------ALVPSFLAFAVVNLLEKHFGHLVDYDFTAKMEDILDLIARGEAE 572
Query: 425 RQEYLSSYYLGSDGLAASVARMEKEID 505
R +L +Y G V E D
Sbjct: 573 RVPWLRRFYFGDGNGEGEVGLKELVTD 599
[154][TOP]
>UniRef100_C0UHD3 DNA topoisomerase n=1 Tax=Gordonia bronchialis DSM 43247
RepID=C0UHD3_9ACTO
Length = 1031
Score = 107 bits (268), Expect = 4e-22
Identities = 66/154 (42%), Positives = 85/154 (55%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + G+ + + L H+T PPAR+T+ASLVK LE LG+GRPSTYASI
Sbjct: 474 GQADDAENRLPQLREGQALRATELSADGHSTNPPARFTEASLVKVLEELGIGRPSTYASI 533
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGYV + AL P AF V LL YF VD FTA +E LD
Sbjct: 534 IGTIQDRGYVVK---------KGNALVPSWIAFAVVGLLEAYFQGLVDYDFTASLEDDLD 584
Query: 401 AIAAGAADRQEYLSSYYLGSDGLAASVARMEKEI 502
IA+G +R +L+ +Y G AA A + EI
Sbjct: 585 EIASGRENRTRWLTEFYFGD---AAPNAEHDAEI 615
[155][TOP]
>UniRef100_Q82EJ4 DNA topoisomerase n=1 Tax=Streptomyces avermitilis
RepID=Q82EJ4_STRAW
Length = 942
Score = 107 bits (267), Expect = 5e-22
Identities = 61/131 (46%), Positives = 77/131 (58%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+P++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVGEGDPLSAEEISVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 AVPWLKRFYFG 597
[156][TOP]
>UniRef100_B8HFR7 DNA topoisomerase n=1 Tax=Arthrobacter chlorophenolicus A6
RepID=B8HFR7_ARTCA
Length = 912
Score = 107 bits (267), Expect = 5e-22
Identities = 62/144 (43%), Positives = 81/144 (56%)
Frame = +2
Query: 32 ARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTY 211
+R + A+ LP+V G+ + S + V H T+PP RYT+ASL ELE G+GRPSTY
Sbjct: 462 SRGDDDSDEARRLPNVAKGDSLKASDIVAVGHETSPPPRYTEASLTAELEKKGIGRPSTY 521
Query: 212 ASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMER 391
AS + T+ RGYV R AL P AF V +LL ++F +VD FTA+ME
Sbjct: 522 ASTISTIQDRGYV---------RKQGSALVPSWIAFSVIRLLEQHFSDYVDYEFTADMEG 572
Query: 392 SLDAIAAGAADRQEYLSSYYLGSD 463
LD IA G A +L +Y G D
Sbjct: 573 DLDKIANGQAAGTSWLRHFYFGED 596
[157][TOP]
>UniRef100_D0BKB4 DNA topoisomerase n=1 Tax=Granulicatella elegans ATCC 700633
RepID=D0BKB4_9LACT
Length = 689
Score = 107 bits (267), Expect = 5e-22
Identities = 58/131 (44%), Positives = 80/131 (61%)
Frame = +2
Query: 59 AQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVL 238
+ VLP++V G+ V+V LD +H T PPARY++A+L+K LE +GVGRPSTYA +ET+
Sbjct: 428 SNVLPELVEGDTVSVQKLDPEQHFTQPPARYSEATLIKTLEEIGVGRPSTYAPTIETIQK 487
Query: 239 RGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGA 418
R YV + A R P L +V Q++ YFP+ VD FTAEME LD I AG
Sbjct: 488 RYYV----KLVAKRFEPTELGE-----IVHQMINNYFPNIVDTHFTAEMESELDQIEAGK 538
Query: 419 ADRQEYLSSYY 451
+ + + +Y
Sbjct: 539 QEWVQVIDRFY 549
[158][TOP]
>UniRef100_C2BKM3 DNA topoisomerase n=1 Tax=Corynebacterium pseudogenitalium ATCC
33035 RepID=C2BKM3_9CORY
Length = 991
Score = 107 bits (267), Expect = 5e-22
Identities = 65/145 (44%), Positives = 83/145 (57%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G + + H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+ RGY
Sbjct: 476 LPHLEEGRALTAKEVSAEGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQDRGY 535
Query: 248 -VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
VSRG AL P AF V LL F VD FT+ ME LD IA G D
Sbjct: 536 VVSRG----------NALVPSWVAFAVVGLLEENFTELVDYDFTSSMEDELDQIATGIED 585
Query: 425 RQEYLSSYYLG----SDGLAASVAR 487
+L+ +Y G ++ AAS+AR
Sbjct: 586 GTAWLNGFYFGNAEANEQKAASIAR 610
[159][TOP]
>UniRef100_UPI00019E636F DNA topoisomerase I n=1 Tax=Desulfotomaculum acetoxidans DSM 771
RepID=UPI00019E636F
Length = 690
Score = 107 bits (266), Expect = 7e-22
Identities = 57/130 (43%), Positives = 78/130 (60%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
+ LP++ GE + ++ L +H T PP RYTDASL+K LE G+GRPSTYA IVET+ R
Sbjct: 426 KTLPELAEGEKLELTELLPKQHFTQPPPRYTDASLIKLLEENGIGRPSTYAPIVETIQKR 485
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
GYVSR ++ P FVV ++L+ +FP +D FTA+ME+ LD I G
Sbjct: 486 GYVSRENKQ---------FFPTELGFVVVEMLKEHFPEIIDVEFTADMEKKLDHIEEGDT 536
Query: 422 DRQEYLSSYY 451
D + L +Y
Sbjct: 537 DWIKILEEFY 546
[160][TOP]
>UniRef100_UPI000185C7DF DNA topoisomerase I n=1 Tax=Propionibacterium acnes SK137
RepID=UPI000185C7DF
Length = 929
Score = 107 bits (266), Expect = 7e-22
Identities = 62/143 (43%), Positives = 80/143 (55%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPST 208
S G S A + LP + G+ + + H T PPARYT+ SLV +LE L +GRPST
Sbjct: 456 SVDEGASDDAQKRLPQLSKGQDLDPREVTAKGHDTRPPARYTEPSLVAKLEELEIGRPST 515
Query: 209 YASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEME 388
YASI+ T+ R YV + AL P AF V +LL +F + VD FTA+ME
Sbjct: 516 YASIIRTITSRDYVFK---------KGSALVPTWLAFAVTRLLEEHFSNLVDYQFTADME 566
Query: 389 RSLDAIAAGAADRQEYLSSYYLG 457
+LD IA G ADR LS++Y G
Sbjct: 567 ETLDQIARGNADRVAVLSAFYFG 589
[161][TOP]
>UniRef100_Q6AB64 DNA topoisomerase n=1 Tax=Propionibacterium acnes
RepID=Q6AB64_PROAC
Length = 929
Score = 107 bits (266), Expect = 7e-22
Identities = 62/143 (43%), Positives = 80/143 (55%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPST 208
S G S A + LP + G+ + + H T PPARYT+ SLV +LE L +GRPST
Sbjct: 456 SVDEGASDDAQKRLPQLSKGQDLDPREVTAKGHDTRPPARYTEPSLVAKLEELEIGRPST 515
Query: 209 YASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEME 388
YASI+ T+ R YV + AL P AF V +LL +F + VD FTA+ME
Sbjct: 516 YASIIRTITSRDYVFK---------KGSALVPTWLAFAVTRLLEEHFSNLVDYQFTADME 566
Query: 389 RSLDAIAAGAADRQEYLSSYYLG 457
+LD IA G ADR LS++Y G
Sbjct: 567 ETLDQIARGNADRVAVLSAFYFG 589
[162][TOP]
>UniRef100_Q2S3I6 DNA topoisomerase n=1 Tax=Salinibacter ruber DSM 13855
RepID=Q2S3I6_SALRD
Length = 862
Score = 107 bits (266), Expect = 7e-22
Identities = 66/155 (42%), Positives = 83/155 (53%), Gaps = 9/155 (5%)
Frame = +2
Query: 68 LPDVVPGEPVAVSA---------LDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
LP + GE A SA ++ + H T PP+RYT+ASLV+ LE G+GRPSTYASI
Sbjct: 466 LPPLEVGETAAQSADDDGFQVRSVEPLGHETKPPSRYTEASLVETLEEEGIGRPSTYASI 525
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGYV R AL P TAF + L+ F VD FTAEME LD
Sbjct: 526 IGTIQQRGYV---------RKKGSALVPTFTAFATNNLMETQFEPLVDVHFTAEMEDVLD 576
Query: 401 AIAAGAADRQEYLSSYYLGSDGLAASVARMEKEID 505
IA G D YL +Y G +G+ V + +ID
Sbjct: 577 DIARGRKDPTPYLRDFYKGEEGVETRVEQGLDDID 611
[163][TOP]
>UniRef100_Q2RJP9 DNA topoisomerase I n=1 Tax=Moorella thermoacetica ATCC 39073
RepID=Q2RJP9_MOOTA
Length = 697
Score = 107 bits (266), Expect = 7e-22
Identities = 56/139 (40%), Positives = 80/139 (57%)
Frame = +2
Query: 35 RPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYA 214
R G Q LP + G+ + + +L+ +H T PP RYT+A+LVK +E LG+GRPSTYA
Sbjct: 425 RDGEDKDQEQRLPPLATGQTLKLQSLEPKQHFTQPPPRYTEATLVKTMEELGIGRPSTYA 484
Query: 215 SIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERS 394
+ET++ RGYV+R ++ P VV LL+ +FP +D FTA ME
Sbjct: 485 PTIETILQRGYVTREQKQ---------FVPTELGRVVVALLKEHFPKIIDVEFTAHMEEQ 535
Query: 395 LDAIAAGAADRQEYLSSYY 451
LDAI AG ++ L+ +Y
Sbjct: 536 LDAIEAGKISWRQVLAEFY 554
[164][TOP]
>UniRef100_C9NA17 DNA topoisomerase I n=1 Tax=Streptomyces flavogriseus ATCC 33331
RepID=C9NA17_9ACTO
Length = 955
Score = 107 bits (266), Expect = 7e-22
Identities = 62/141 (43%), Positives = 79/141 (56%), Gaps = 1/141 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALTADEVTVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLGSDGLAASVAR 487
+L +Y G+D A +
Sbjct: 587 SVPWLRRFYFGADDDTAGAGK 607
[165][TOP]
>UniRef100_C8W5C5 DNA topoisomerase I n=1 Tax=Desulfotomaculum acetoxidans DSM 771
RepID=C8W5C5_9FIRM
Length = 697
Score = 107 bits (266), Expect = 7e-22
Identities = 57/130 (43%), Positives = 78/130 (60%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
+ LP++ GE + ++ L +H T PP RYTDASL+K LE G+GRPSTYA IVET+ R
Sbjct: 433 KTLPELAEGEKLELTELLPKQHFTQPPPRYTDASLIKLLEENGIGRPSTYAPIVETIQKR 492
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
GYVSR ++ P FVV ++L+ +FP +D FTA+ME+ LD I G
Sbjct: 493 GYVSRENKQ---------FFPTELGFVVVEMLKEHFPEIIDVEFTADMEKKLDHIEEGDT 543
Query: 422 DRQEYLSSYY 451
D + L +Y
Sbjct: 544 DWIKILEEFY 553
[166][TOP]
>UniRef100_C6R7P2 DNA topoisomerase n=1 Tax=Corynebacterium tuberculostearicum SK141
RepID=C6R7P2_9CORY
Length = 991
Score = 107 bits (266), Expect = 7e-22
Identities = 65/145 (44%), Positives = 83/145 (57%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G + + H+T PPARYT+ASLVK++E LG+GRPSTYASI++T+ RGY
Sbjct: 476 LPHLEEGRGLTAKEVSAEGHSTNPPARYTEASLVKKMEDLGIGRPSTYASIIKTIQDRGY 535
Query: 248 -VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
VSRG AL P AF V LL F VD FT+ ME LD IA G D
Sbjct: 536 VVSRG----------NALVPSWVAFAVVGLLEENFTELVDYDFTSSMEDELDQIATGIED 585
Query: 425 RQEYLSSYYLG----SDGLAASVAR 487
+L+ +Y G ++ AAS+AR
Sbjct: 586 GTAWLNGFYFGNAEANEQKAASIAR 610
[167][TOP]
>UniRef100_C2KTI6 DNA topoisomerase n=1 Tax=Mobiluncus mulieris ATCC 35243
RepID=C2KTI6_9ACTO
Length = 1032
Score = 107 bits (266), Expect = 7e-22
Identities = 66/156 (42%), Positives = 85/156 (54%), Gaps = 3/156 (1%)
Frame = +2
Query: 2 SAPVSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLV---EHTTTPPARYTDASLVK 172
+A S S +P LP + P EP+ + LD +H TTPPAR+TDA+LVK
Sbjct: 567 AATAGGSKNSGKPAKEREVR--LPRLAPREPLNLIHLDFSKERQHFTTPPARFTDATLVK 624
Query: 173 ELEALGVGRPSTYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFP 352
+E G+GRPSTYAS + T+V R YV R QAL P AF V +LL P
Sbjct: 625 AMEERGIGRPSTYASTISTIVDRSYVYR---------RGQALVPSWLAFSVVRLLEENLP 675
Query: 353 SFVDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGS 460
VD FTA+ME LD IAAG +R +L ++ G+
Sbjct: 676 GLVDFDFTADMETDLDKIAAGDGNRSAWLRDFWYGT 711
[168][TOP]
>UniRef100_UPI0001AF15B4 putative DNA topoisomerase I n=1 Tax=Streptomyces roseosporus NRRL
11379 RepID=UPI0001AF15B4
Length = 964
Score = 106 bits (265), Expect = 9e-22
Identities = 61/134 (45%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 479 LPQVAEGDALTADEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 538
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 539 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAK 588
Query: 425 RQEYLSSYYLGSDG 466
+L +Y G+ G
Sbjct: 589 SVPWLKRFYFGATG 602
[169][TOP]
>UniRef100_Q83HB7 DNA topoisomerase n=1 Tax=Tropheryma whipplei TW08/27
RepID=Q83HB7_TROW8
Length = 841
Score = 106 bits (265), Expect = 9e-22
Identities = 60/143 (41%), Positives = 81/143 (56%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G +++LP++ G+ V + + V HTT PP RYT+ASLVK LE LG+GRPSTYA I
Sbjct: 444 GLQDLNSKLLPNLQVGDQVTLVDVRAVGHTTLPPPRYTEASLVKVLEELGLGRPSTYALI 503
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGY L + L P AF V LL +F +D FTA +E LD
Sbjct: 504 LRTIQERGY---------AHLRNRMLVPDWLAFSVVNLLENFFSRLIDYDFTANLEDQLD 554
Query: 401 AIAAGAADRQEYLSSYYLGSDGL 469
IA G+ +R ++L +Y G D L
Sbjct: 555 EIALGSQNRSDWLRKFYFGDDNL 577
[170][TOP]
>UniRef100_Q83FM2 DNA topoisomerase n=1 Tax=Tropheryma whipplei str. Twist
RepID=Q83FM2_TROWT
Length = 841
Score = 106 bits (265), Expect = 9e-22
Identities = 60/143 (41%), Positives = 81/143 (56%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G +++LP++ G+ V + + V HTT PP RYT+ASLVK LE LG+GRPSTYA I
Sbjct: 444 GLQDLNSKLLPNLQVGDQVTLVDVRAVGHTTLPPPRYTEASLVKVLEELGLGRPSTYALI 503
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGY L + L P AF V LL +F +D FTA +E LD
Sbjct: 504 LSTIQERGY---------AHLRNRMLVPDWLAFSVVNLLENFFSRLIDYDFTANLEDQLD 554
Query: 401 AIAAGAADRQEYLSSYYLGSDGL 469
IA G+ +R ++L +Y G D L
Sbjct: 555 EIALGSQNRSDWLRKFYFGDDNL 577
[171][TOP]
>UniRef100_Q4JSS2 DNA topoisomerase n=1 Tax=Corynebacterium jeikeium K411
RepID=Q4JSS2_CORJK
Length = 997
Score = 106 bits (265), Expect = 9e-22
Identities = 62/135 (45%), Positives = 80/135 (59%), Gaps = 1/135 (0%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + + H+T PPARYT+ASLVK++E +G+GRPSTYASI+ T+
Sbjct: 479 AEKRLPQLTKGDELNARDVAADGHSTNPPARYTEASLVKKMEEMGIGRPSTYASIIRTIQ 538
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV RG AL P AF V LL + F + VD FT+ ME LDAIAA
Sbjct: 539 DRGYVLPRG----------NALVPSWVAFAVIGLLEQNFGALVDYDFTSAMEDELDAIAA 588
Query: 413 GAADRQEYLSSYYLG 457
G DR +L +Y G
Sbjct: 589 GNEDRVNWLKGFYFG 603
[172][TOP]
>UniRef100_C5BY25 DNA topoisomerase n=1 Tax=Beutenbergia cavernae DSM 12333
RepID=C5BY25_BEUC1
Length = 913
Score = 106 bits (265), Expect = 9e-22
Identities = 65/155 (41%), Positives = 84/155 (54%), Gaps = 5/155 (3%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G+S LPD+ G+ VA +L H T+PP RYT+ASL LE G+GRPST+A+
Sbjct: 479 GSSAARETRLPDLAQGDQVAAESLTAEGHDTSPPPRYTEASLTAALEERGIGRPSTFAAT 538
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ +V RGYV R QAL P AF V +LL +F VD FTA ME LD
Sbjct: 539 ISVIVDRGYVLR---------RGQALVPSWLAFSVVRLLEDHFGRLVDYDFTAAMESDLD 589
Query: 401 AIAAGAADRQEYLSSYYL-----GSDGLAASVARM 490
IA G DR +L+ +Y GS+GL V+ +
Sbjct: 590 RIARGEQDRVAWLTRFYFGDEAAGSEGLQQLVSEL 624
[173][TOP]
>UniRef100_B1VM20 DNA topoisomerase n=1 Tax=Streptomyces griseus subsp. griseus NBRC
13350 RepID=B1VM20_STRGG
Length = 963
Score = 106 bits (265), Expect = 9e-22
Identities = 60/133 (45%), Positives = 78/133 (58%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 479 LPQVAEGDALSADEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 538
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD I+ G A
Sbjct: 539 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRISRGEAQ 588
Query: 425 RQEYLSSYYLGSD 463
+L +Y G+D
Sbjct: 589 SVPWLKRFYFGAD 601
[174][TOP]
>UniRef100_A1R9W8 DNA topoisomerase n=1 Tax=Arthrobacter aurescens TC1
RepID=A1R9W8_ARTAT
Length = 907
Score = 106 bits (265), Expect = 9e-22
Identities = 62/144 (43%), Positives = 81/144 (56%)
Frame = +2
Query: 32 ARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTY 211
+R + A+ LP+V G+ + S + V H T+PP RYT+ASL ELE G+GRPSTY
Sbjct: 458 SRGDEESDEARRLPNVAKGDSLTASDILAVGHETSPPPRYTEASLTAELEKRGIGRPSTY 517
Query: 212 ASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMER 391
AS + T+ RGYV R AL P AF V +LL ++F +VD FTA+ME
Sbjct: 518 ASTISTIQDRGYV---------RKQGSALVPSWIAFSVIRLLEQHFTDYVDYEFTADMEG 568
Query: 392 SLDAIAAGAADRQEYLSSYYLGSD 463
LD IA G A +L +Y G D
Sbjct: 569 DLDKIANGQAVGAAWLKHFYYGED 592
[175][TOP]
>UniRef100_C8RV02 DNA topoisomerase n=1 Tax=Corynebacterium jeikeium ATCC 43734
RepID=C8RV02_CORJE
Length = 997
Score = 106 bits (265), Expect = 9e-22
Identities = 62/135 (45%), Positives = 80/135 (59%), Gaps = 1/135 (0%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP + G+ + + H+T PPARYT+ASLVK++E +G+GRPSTYASI+ T+
Sbjct: 479 AEKRLPQLTKGDELNARDVAADGHSTNPPARYTEASLVKKMEEMGIGRPSTYASIIRTIQ 538
Query: 236 LRGYV-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV RG AL P AF V LL + F + VD FT+ ME LDAIAA
Sbjct: 539 DRGYVLPRG----------NALVPSWVAFAVIGLLEQNFGALVDYDFTSAMEDELDAIAA 588
Query: 413 GAADRQEYLSSYYLG 457
G DR +L +Y G
Sbjct: 589 GNEDRVNWLKGFYFG 603
[176][TOP]
>UniRef100_B5HVG2 DNA topoisomerase n=1 Tax=Streptomyces sviceus ATCC 29083
RepID=B5HVG2_9ACTO
Length = 957
Score = 106 bits (265), Expect = 9e-22
Identities = 61/131 (46%), Positives = 77/131 (58%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 490 LPQVAQGDALSAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 549
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IAAG A
Sbjct: 550 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIAAGQAQ 599
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 600 SVPWLRRFYFG 610
[177][TOP]
>UniRef100_C1ZPX2 DNA topoisomerase n=1 Tax=Rhodothermus marinus DSM 4252
RepID=C1ZPX2_RHOMR
Length = 858
Score = 106 bits (264), Expect = 1e-21
Identities = 60/149 (40%), Positives = 81/149 (54%), Gaps = 1/149 (0%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
Q LP + G+ ++ H T PPARYT+A+LVK LE G+GRPSTYA+I++T++ R
Sbjct: 465 QPLPPLKKGDRPRCVQVESRRHETRPPARYTEATLVKTLEQEGIGRPSTYATIIDTILQR 524
Query: 242 GY-VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGA 418
GY V RG + L P AF + LL F VD FTA+ME +LD IA G
Sbjct: 525 GYAVRRGNQ----------LVPTFMAFATNNLLEACFEKLVDLGFTAQMEEALDEIAQGR 574
Query: 419 ADRQEYLSSYYLGSDGLAASVARMEKEID 505
YL +Y G +GL + + +D
Sbjct: 575 QKTVPYLRQFYQGEEGLERMIDEALRRVD 603
[178][TOP]
>UniRef100_UPI0001B57B9D DNA topoisomerase I n=1 Tax=Streptomyces sp. AA4
RepID=UPI0001B57B9D
Length = 957
Score = 105 bits (263), Expect = 1e-21
Identities = 62/142 (43%), Positives = 82/142 (57%), Gaps = 1/142 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + + + L H+T+PPARY++ SLV +LE LG+GRPSTYASI++T+ RGY
Sbjct: 487 LPVLAKDQALTAPELSADGHSTSPPARYSEPSLVSKLEELGIGRPSTYASIIKTIQDRGY 546
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V L+ R+F VD FTA +E LD IA G R
Sbjct: 547 VWK---------KGSALVPSWVAFAVVGLMERHFERLVDYNFTAGLEDELDRIANGDEHR 597
Query: 428 QEYLSSYYLGSD-GLAASVARM 490
E+LS +Y G D G+ SV R+
Sbjct: 598 VEWLSKFYFGGDFGVEGSVGRL 619
[179][TOP]
>UniRef100_UPI0001B54765 putative DNA topoisomerase I n=1 Tax=Streptomyces sp. C
RepID=UPI0001B54765
Length = 943
Score = 105 bits (263), Expect = 1e-21
Identities = 61/133 (45%), Positives = 77/133 (57%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + H+T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 476 LPQVAEGDALTAEEITADGHSTKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 535
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL +F VD FTA+ME LD IA G A
Sbjct: 536 VFKKGT----------ALVPSFLSFAVVNLLETHFGRLVDYDFTAKMEDDLDRIARGEAQ 585
Query: 425 RQEYLSSYYLGSD 463
+L +Y GS+
Sbjct: 586 SVPWLKRFYFGSE 598
[180][TOP]
>UniRef100_B5RQG5 DNA topoisomerase n=1 Tax=Borrelia recurrentis A1
RepID=B5RQG5_BORRA
Length = 845
Score = 105 bits (263), Expect = 1e-21
Identities = 55/139 (39%), Positives = 83/139 (59%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ + + +H T PP RYT+ASLV++LE G+GRPSTYA+I+ TL R YV +
Sbjct: 460 GDKFTILNIKPEQHETKPPLRYTEASLVQKLEKEGIGRPSTYATIISTLFEREYVFKQN- 518
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL++YFP ++ FT+ ME +LD IA G D+ +YL++
Sbjct: 519 --------NTLIPTIKGAAVINLLKKYFPILIELQFTSNMEENLDKIAIGKLDKIQYLNA 570
Query: 446 YYLGSDGLAASVARMEKEI 502
+Y G +GL +V+++E I
Sbjct: 571 FYNGKEGLKNTVSKIEPMI 589
[181][TOP]
>UniRef100_B5RN26 DNA topoisomerase n=1 Tax=Borrelia duttonii Ly RepID=B5RN26_BORDL
Length = 845
Score = 105 bits (263), Expect = 1e-21
Identities = 55/139 (39%), Positives = 83/139 (59%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ + + +H T PP RYT+ASLV++LE G+GRPSTYA+I+ TL R YV +
Sbjct: 460 GDKFTILNIKPEQHETKPPLRYTEASLVQKLEKEGIGRPSTYATIISTLFEREYVFKQN- 518
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL++YFP ++ FT+ ME +LD IA G D+ +YL++
Sbjct: 519 --------NTLIPTIKGAAVINLLKKYFPILIELQFTSNMEENLDKIAIGKLDKIQYLNA 570
Query: 446 YYLGSDGLAASVARMEKEI 502
+Y G +GL +V+++E I
Sbjct: 571 FYNGKEGLKNTVSKIEPMI 589
[182][TOP]
>UniRef100_C6R379 DNA topoisomerase n=1 Tax=Rothia mucilaginosa ATCC 25296
RepID=C6R379_9MICC
Length = 933
Score = 105 bits (263), Expect = 1e-21
Identities = 57/134 (42%), Positives = 80/134 (59%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A + LP++ GE + A++ H T PP RYT+ASLVK L+ LG+GRPSTYA+++ T++
Sbjct: 469 AEKRLPNLTTGEALTAEAIEPAGHETLPPPRYTEASLVKTLDELGIGRPSTYAAVISTIM 528
Query: 236 LRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAG 415
RGYV+ + +L P AF V +LL F +V+ FTA+ME LD IA G
Sbjct: 529 DRGYVN---------VRSGSLIPSWIAFSVVRLLESSFGPYVNYEFTAQMEEDLDRIARG 579
Query: 416 AADRQEYLSSYYLG 457
R E+L +Y G
Sbjct: 580 EESRVEWLGEFYFG 593
[183][TOP]
>UniRef100_B5HA95 DNA topoisomerase n=1 Tax=Streptomyces pristinaespiralis ATCC 25486
RepID=B5HA95_STRPR
Length = 934
Score = 105 bits (263), Expect = 1e-21
Identities = 64/140 (45%), Positives = 81/140 (57%), Gaps = 1/140 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALSSEEISVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLGSDGLAASVA 484
+L +Y G +G AA A
Sbjct: 587 AVPWLRRFYFG-EGDAAGAA 605
[184][TOP]
>UniRef100_B5GPN9 DNA topoisomerase n=1 Tax=Streptomyces clavuligerus ATCC 27064
RepID=B5GPN9_STRCL
Length = 948
Score = 105 bits (263), Expect = 1e-21
Identities = 63/145 (43%), Positives = 80/145 (55%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 466 LPQVTEGDGLTAEEISADGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 525
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA+ME LD IA G A
Sbjct: 526 VFKKGT----------ALVPSFLSFAVVNLLEKHFGQLVDYDFTAKMEDDLDCIARGEAQ 575
Query: 425 RQEYLSSYYL----GSDGLAASVAR 487
+L +Y G +G A+ R
Sbjct: 576 AVPWLKRFYFGEGEGGEGTGAAAGR 600
[185][TOP]
>UniRef100_UPI0001B4BD30 DNA topoisomerase I n=1 Tax=Streptomyces viridochromogenes DSM
40736 RepID=UPI0001B4BD30
Length = 942
Score = 105 bits (262), Expect = 2e-21
Identities = 60/131 (45%), Positives = 77/131 (58%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVSEGDALSAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD +FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYSFTASMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 AVPWLKRFYFG 597
[186][TOP]
>UniRef100_Q0VQT8 DNA topoisomerase n=1 Tax=Alcanivorax borkumensis SK2
RepID=Q0VQT8_ALCBS
Length = 909
Score = 105 bits (262), Expect = 2e-21
Identities = 59/141 (41%), Positives = 87/141 (61%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPST 208
++R G T +LPDV G+ +A+ +D +H T PPAR+T+ASLVKELE G+GRPST
Sbjct: 453 ASRKGQEDT---LLPDVKEGDVLAIDNVDANQHFTKPPARFTEASLVKELEKRGIGRPST 509
Query: 209 YASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEME 388
YA+I+ T+ RGYV + R + A ++ V D+L+ FP+ +D FTA ME
Sbjct: 510 YAAIISTIQDRGYVRQDNR--------RFYAEKMGDIVTDRLVES-FPNLMDYGFTASME 560
Query: 389 RSLDAIAAGAADRQEYLSSYY 451
+LD +A G + Q+ L+ +Y
Sbjct: 561 ETLDEVAEGRRNWQDVLNEFY 581
[187][TOP]
>UniRef100_C7MQK9 DNA topoisomerase I n=1 Tax=Saccharomonospora viridis DSM 43017
RepID=C7MQK9_SACVD
Length = 921
Score = 105 bits (262), Expect = 2e-21
Identities = 59/131 (45%), Positives = 79/131 (60%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP +V + + + L H T+PP+RY++ SLV +LE LG+GRPSTYASI++T+ RGY
Sbjct: 489 LPRLVKDQSLTATELRPDSHATSPPSRYSEPSLVSKLEELGIGRPSTYASIIKTIQDRGY 548
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V L+ R+F VD FTA ME LD IAAG +R
Sbjct: 549 VWK---------KGSALVPSWVAFSVVGLMERHFERLVDYYFTAAMEDELDRIAAGEEER 599
Query: 428 QEYLSSYYLGS 460
E+LS +Y G+
Sbjct: 600 TEWLSRFYFGN 610
[188][TOP]
>UniRef100_C2A035 DNA topoisomerase n=1 Tax=Sulfurospirillum deleyianum DSM 6946
RepID=C2A035_SULDE
Length = 690
Score = 105 bits (262), Expect = 2e-21
Identities = 59/149 (39%), Positives = 89/149 (59%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LPD+ + V +S LD +H T PP+RY++ASL+K+LE+LG+GRPSTYA + L R
Sbjct: 425 KLLPDLALKQEVTLSKLDANQHFTEPPSRYSEASLIKKLESLGIGRPSTYAPTISVLSAR 484
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
Y++ + + + P AF V +LL ++FP VD++FT+ ME LD IA
Sbjct: 485 DYIN---------IEKKQIVPTEVAFQVTELLEQHFPQIVDSSFTSTMEERLDLIAEDKE 535
Query: 422 DRQEYLSSYYLGSDGLAASVARMEKEIDT 508
D Q L ++Y D A VA+ + EI +
Sbjct: 536 DWQAILWNFYEPFD---AQVAKGKTEIQS 561
[189][TOP]
>UniRef100_B4VDJ0 DNA topoisomerase n=1 Tax=Streptomyces sp. Mg1 RepID=B4VDJ0_9ACTO
Length = 954
Score = 105 bits (262), Expect = 2e-21
Identities = 61/133 (45%), Positives = 78/133 (58%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + H+T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 476 LPQVSEGDALSAEEITADGHSTKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 535
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL +F VD FTA+ME LD IA G A
Sbjct: 536 VFKKGT----------ALVPSFLSFAVVNLLETHFGRLVDYDFTAKMEDDLDRIARGEAQ 585
Query: 425 RQEYLSSYYLGSD 463
+L +Y GS+
Sbjct: 586 SVPWLKRFYFGSE 598
[190][TOP]
>UniRef100_C7M1S8 DNA topoisomerase I n=1 Tax=Acidimicrobium ferrooxidans DSM 10331
RepID=C7M1S8_ACIFD
Length = 850
Score = 105 bits (261), Expect = 3e-21
Identities = 64/148 (43%), Positives = 79/148 (53%), Gaps = 2/148 (1%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G + + H T PPARYT+ASLV+ LE G+GRPSTYA I+ TLV R Y
Sbjct: 466 LPPLAAGVALTTTGAQPQGHETQPPARYTEASLVRALEERGIGRPSTYAQIISTLVERSY 525
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
R + QAL P F V QLL R+F VD +FTA +E LD IA G +
Sbjct: 526 AWRRS---------QALIPTFLGFAVVQLLERHFAELVDYSFTARLEDDLDRIAIGEEEP 576
Query: 428 QEYLSSYYL--GSDGLAASVARMEKEID 505
YL+ +Y G+ GL V EID
Sbjct: 577 TPYLAHFYWGNGAPGLHQLVTERLGEID 604
[191][TOP]
>UniRef100_B8DVL2 DNA topoisomerase n=4 Tax=Bifidobacterium animalis subsp. lactis
RepID=B8DVL2_BIFA0
Length = 986
Score = 105 bits (261), Expect = 3e-21
Identities = 60/121 (49%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +2
Query: 125 HTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYV-SRGTRETAGRLPPQALA 301
H T PPARYT+ASLVK LEA +GRPSTYA+I+ T++ RGYV RG +AL
Sbjct: 489 HETQPPARYTEASLVKTLEAKEIGRPSTYANIISTIIDRGYVYERG----------RALI 538
Query: 302 PRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAASV 481
P AF V +LL FP +VD FTA+ME LD IA G +E+L+ +Y GS +A
Sbjct: 539 PSWLAFAVTRLLETKFPKYVDYQFTADMENGLDQIAHGNETGREWLTQFYFGSGADSARS 598
Query: 482 A 484
A
Sbjct: 599 A 599
[192][TOP]
>UniRef100_B7ICM2 DNA topoisomerase n=1 Tax=Thermosipho africanus TCF52B
RepID=B7ICM2_THEAB
Length = 700
Score = 104 bits (260), Expect = 3e-21
Identities = 55/126 (43%), Positives = 77/126 (61%)
Frame = +2
Query: 74 DVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVS 253
D+ G+ VS +++ + TT PPAR+T+ASLVK LEA G+GRPSTYA+I+ TL+ R YV
Sbjct: 422 DLEKGKTYKVSKINIEKDTTKPPARFTEASLVKTLEAEGIGRPSTYATIISTLLARKYVK 481
Query: 254 RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQE 433
+ +E L P L F V+ L + FP VD FTA ME LD + +G + +E
Sbjct: 482 KENKE---------LIPTLLGFTVEDFLTKRFPEIVDKKFTALMEEELDKVESGEKEWKE 532
Query: 434 YLSSYY 451
L ++Y
Sbjct: 533 VLDNFY 538
[193][TOP]
>UniRef100_C9Z2D8 DNA topoisomerase I n=1 Tax=Streptomyces scabiei 87.22
RepID=C9Z2D8_STRSC
Length = 948
Score = 104 bits (260), Expect = 3e-21
Identities = 64/141 (45%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVGEGDALSAEQITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA+ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTAKMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYL----GSDGLAA 475
+L +Y GS G AA
Sbjct: 587 AVPWLKRFYFGEGTGSGGTAA 607
[194][TOP]
>UniRef100_B4WZG7 DNA topoisomerase n=1 Tax=Alcanivorax sp. DG881 RepID=B4WZG7_9GAMM
Length = 914
Score = 104 bits (260), Expect = 3e-21
Identities = 58/141 (41%), Positives = 87/141 (61%)
Frame = +2
Query: 29 SARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPST 208
++R G T +LPDV G+ +++ +D +H T PPAR+T+ASLVKELE G+GRPST
Sbjct: 453 ASRKGQEDT---LLPDVKEGDVLSIDNVDANQHFTKPPARFTEASLVKELEKRGIGRPST 509
Query: 209 YASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEME 388
YA+I+ T+ RGYV + R + A ++ V D+L+ FP+ +D FTA ME
Sbjct: 510 YAAIISTIQDRGYVRQDNR--------RFYAEKMGDIVTDRLVEN-FPNLMDYGFTASME 560
Query: 389 RSLDAIAAGAADRQEYLSSYY 451
+LD +A G + Q+ L+ +Y
Sbjct: 561 ETLDEVAEGQRNWQDVLNEFY 581
[195][TOP]
>UniRef100_UPI0001B50491 DNA topoisomerase I n=1 Tax=Streptomyces lividans TK24
RepID=UPI0001B50491
Length = 952
Score = 104 bits (259), Expect = 4e-21
Identities = 60/131 (45%), Positives = 75/131 (57%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALTAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 SVPWLRRFYFG 597
[196][TOP]
>UniRef100_UPI0001B4E2DA DNA topoisomerase I n=1 Tax=Streptomyces griseoflavus Tu4000
RepID=UPI0001B4E2DA
Length = 942
Score = 104 bits (259), Expect = 4e-21
Identities = 60/131 (45%), Positives = 76/131 (58%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ ++ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALSAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAR 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 AVPWLKRFYFG 597
[197][TOP]
>UniRef100_A0K0B0 DNA topoisomerase n=1 Tax=Arthrobacter sp. FB24 RepID=A0K0B0_ARTS2
Length = 911
Score = 104 bits (259), Expect = 4e-21
Identities = 61/144 (42%), Positives = 80/144 (55%)
Frame = +2
Query: 32 ARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTY 211
+R + A+ LP+V + + S + V H T+PP RYT+ASL ELE G+GRPSTY
Sbjct: 461 SRGDDDSEEARRLPNVAKDDALTASEIVAVGHETSPPPRYTEASLTAELEKKGIGRPSTY 520
Query: 212 ASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMER 391
AS + T+ RGYV R AL P AF V +LL ++F +VD FTA+ME
Sbjct: 521 ASTISTIQDRGYV---------RKQGSALVPSWIAFSVIRLLEQHFHDYVDYEFTADMEG 571
Query: 392 SLDAIAAGAADRQEYLSSYYLGSD 463
LD IA G A +L +Y G D
Sbjct: 572 DLDKIANGQAVGAAWLKHFYYGED 595
[198][TOP]
>UniRef100_C7H9Z8 DNA topoisomerase n=1 Tax=Faecalibacterium prausnitzii A2-165
RepID=C7H9Z8_9FIRM
Length = 694
Score = 104 bits (259), Expect = 4e-21
Identities = 59/146 (40%), Positives = 85/146 (58%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + + L + T PPARYT+A+L+K LE G+GRPSTYA I+ T++ RGY
Sbjct: 434 LPPLEQGQLLKLKELKSEQKFTQPPARYTEATLIKALEENGIGRPSTYAPIITTIIDRGY 493
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R ++ L P L VD L+ FP VD F+AEME++LD I +G AD
Sbjct: 494 VEREQKK---------LKPTLLGRAVDGLMLEQFPHIVDVDFSAEMEKNLDKIESGKADW 544
Query: 428 QEYLSSYYLGSDGLAASVARMEKEID 505
+ + +Y G AAS+ + EK ++
Sbjct: 545 HKTVDDFY---QGFAASLEQAEKNME 567
[199][TOP]
>UniRef100_Q9X909 DNA topoisomerase 1 n=1 Tax=Streptomyces coelicolor
RepID=TOP1_STRCO
Length = 952
Score = 104 bits (259), Expect = 4e-21
Identities = 60/131 (45%), Positives = 75/131 (57%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALTAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 SVPWLRRFYFG 597
[200][TOP]
>UniRef100_UPI0001AEF12F DNA topoisomerase I n=1 Tax=Streptomyces ghanaensis ATCC 14672
RepID=UPI0001AEF12F
Length = 944
Score = 103 bits (258), Expect = 6e-21
Identities = 60/131 (45%), Positives = 74/131 (56%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + H T PPARYT+ASLVKELE +GRPSTYASI+ T++ RGY
Sbjct: 477 LPQVAEGDALVAEEITADGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGY 536
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA ME LD IA G A
Sbjct: 537 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQ 586
Query: 425 RQEYLSSYYLG 457
+L +Y G
Sbjct: 587 AVPWLKRFYFG 597
[201][TOP]
>UniRef100_B2S1H2 DNA topoisomerase n=1 Tax=Borrelia hermsii DAH RepID=B2S1H2_BORHD
Length = 845
Score = 103 bits (258), Expect = 6e-21
Identities = 52/124 (41%), Positives = 76/124 (61%)
Frame = +2
Query: 122 EHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTRETAGRLPPQALA 301
EH T PP RYT+ASLV++LE G+GRPSTY++I+ TL R Y+ + L
Sbjct: 472 EHETKPPLRYTEASLVQKLEKEGIGRPSTYSTIISTLFEREYIFKQN---------NTLI 522
Query: 302 PRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSSYYLGSDGLAASV 481
P + V LL++YFP ++ FT+ ME +LD IA G D+ +YL+ +Y G +GL +V
Sbjct: 523 PTIKGAAVTNLLKKYFPVLIELKFTSHMEENLDKIAIGTLDKIKYLNKFYNGEEGLKNTV 582
Query: 482 ARME 493
++E
Sbjct: 583 NKIE 586
[202][TOP]
>UniRef100_B0TH92 DNA topoisomerase n=1 Tax=Heliobacterium modesticaldum Ice1
RepID=B0TH92_HELMI
Length = 726
Score = 103 bits (258), Expect = 6e-21
Identities = 60/142 (42%), Positives = 81/142 (57%)
Frame = +2
Query: 26 MSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPS 205
+ R S +LP+V E + + L+ +H T PP RY++A+LV+ LE G+GRPS
Sbjct: 420 IEGRDDDSKEEEGLLPEVSVDEKLDLQKLEPKQHFTQPPPRYSEATLVRALEERGIGRPS 479
Query: 206 TYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEM 385
TYA I+ET+V RGYV R + Q L VVD LL+ +FP +D FTA+M
Sbjct: 480 TYAPIIETIVARGYVVREDK--------QFYLTELGEVVVD-LLKEHFPDIIDVEFTADM 530
Query: 386 ERSLDAIAAGAADRQEYLSSYY 451
E LDAI GAAD + L +Y
Sbjct: 531 EAKLDAIEEGAADWRRILRDFY 552
[203][TOP]
>UniRef100_C0XU91 DNA topoisomerase n=1 Tax=Corynebacterium lipophiloflavum DSM 44291
RepID=C0XU91_9CORY
Length = 975
Score = 103 bits (258), Expect = 6e-21
Identities = 62/145 (42%), Positives = 84/145 (57%), Gaps = 5/145 (3%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + + H+T PPARY +ASLVK++E LG+GRPSTYASI++T+ RGY
Sbjct: 471 LPQLSKGDVLTTVKITADGHSTNPPARYNEASLVKKMEDLGIGRPSTYASIIKTIQDRGY 530
Query: 248 -VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V+RG AL P AF V L+ F + VD FT+ ME LD IA G +
Sbjct: 531 VVARG----------NALVPTWVAFSVIGLMENNFDALVDYDFTSSMEDELDEIAHGNEN 580
Query: 425 RQEYLSSYYLG----SDGLAASVAR 487
R +LS +Y G D +A ++AR
Sbjct: 581 RTRWLSGFYFGDASADDNMADAIAR 605
[204][TOP]
>UniRef100_UPI00016B373F DNA topoisomerase I n=1 Tax=Borrelia afzelii ACA-1
RepID=UPI00016B373F
Length = 849
Score = 103 bits (257), Expect = 7e-21
Identities = 54/142 (38%), Positives = 83/142 (58%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T PP RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDIFSIVKMQTSEHETKPPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLN- 518
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 519 --------NTLIPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +I+++
Sbjct: 571 FYNGKKGLKDTVMQLEPKINSS 592
[205][TOP]
>UniRef100_Q0SM23 DNA topoisomerase n=1 Tax=Borrelia afzelii PKo RepID=Q0SM23_BORAP
Length = 849
Score = 103 bits (257), Expect = 7e-21
Identities = 54/142 (38%), Positives = 83/142 (58%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T PP RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDIFSIVKMQTSEHETKPPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLN- 518
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 519 --------NTLIPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +I+++
Sbjct: 571 FYNGKKGLKDTVMQLEPKINSS 592
[206][TOP]
>UniRef100_A1R0Q3 DNA topoisomerase n=1 Tax=Borrelia turicatae 91E135
RepID=A1R0Q3_BORT9
Length = 845
Score = 103 bits (257), Expect = 7e-21
Identities = 52/136 (38%), Positives = 81/136 (59%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ + ++ EH T PP RYT+ASLV++LE G+GRPSTY++I+ TL R Y+ +
Sbjct: 460 GDKFVILDVNPEEHETKPPLRYTEASLVQKLEKEGIGRPSTYSTIISTLFEREYIFKHN- 518
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL++YFP ++ FT+ ME +LD IA G D+ +YL+
Sbjct: 519 --------NTLIPTIKGAAVINLLKKYFPVLIELKFTSHMEENLDKIAIGTLDKIKYLNK 570
Query: 446 YYLGSDGLAASVARME 493
+Y G +GL ++ ++E
Sbjct: 571 FYNGEEGLKNTINKIE 586
[207][TOP]
>UniRef100_A6Q6D9 DNA topoisomerase n=1 Tax=Sulfurovum sp. NBC37-1 RepID=A6Q6D9_SULNB
Length = 732
Score = 103 bits (256), Expect = 1e-20
Identities = 51/130 (39%), Positives = 78/130 (60%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP++ +PV++ + +H T PPARY +ASL+K+LE+LG+GRPSTYA + L R
Sbjct: 427 KLLPELKKEQPVSLDDIKAEQHFTEPPARYNEASLIKKLESLGIGRPSTYAPTITILQTR 486
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
Y+ + + + P AF V ++L ++FP VD+ FTA ME +LD +A G
Sbjct: 487 KYI---------EIEKKRIHPTEIAFTVIEMLEKHFPEIVDSGFTANMEETLDKVAEGET 537
Query: 422 DRQEYLSSYY 451
D Q L +Y
Sbjct: 538 DWQTILKEFY 547
[208][TOP]
>UniRef100_A5D2W4 DNA topoisomerase n=1 Tax=Pelotomaculum thermopropionicum SI
RepID=A5D2W4_PELTS
Length = 714
Score = 103 bits (256), Expect = 1e-20
Identities = 56/130 (43%), Positives = 77/130 (59%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP++ GE + +L +H T PP RYTDASLV+ LE G+GRPSTYA IVET++ R
Sbjct: 435 KLLPELKEGEEIEARSLTPRQHFTQPPPRYTDASLVRALEEKGIGRPSTYAPIVETILKR 494
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
GYV R ++ P +V LL+++F +D FTA ME SLD+I G
Sbjct: 495 GYVVRENKQ---------FFPTELGMIVVDLLKKHFKEIIDIDFTAGMEESLDSIEEGEL 545
Query: 422 DRQEYLSSYY 451
D + L S+Y
Sbjct: 546 DWIKVLESFY 555
[209][TOP]
>UniRef100_A4F6Q1 DNA topoisomerase n=1 Tax=Saccharopolyspora erythraea NRRL 2338
RepID=A4F6Q1_SACEN
Length = 922
Score = 103 bits (256), Expect = 1e-20
Identities = 60/141 (42%), Positives = 77/141 (54%)
Frame = +2
Query: 41 GTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASI 220
G + A LP + + V L H+T PP RYT+ASLVK LE LG+GRPSTYASI
Sbjct: 456 GVADDAESRLPRLAQYQAVTAPELSPDGHSTNPPPRYTEASLVKALEELGIGRPSTYASI 515
Query: 221 VETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLD 400
+ T+ RGYV + AL P AF V L+ ++F VD FTA +E LD
Sbjct: 516 ISTVQDRGYVWK---------KGSALVPSWVAFAVVGLMEKHFGRLVDYDFTAALEDELD 566
Query: 401 AIAAGAADRQEYLSSYYLGSD 463
IA G R ++LS +Y G +
Sbjct: 567 RIAEGRQQRTKWLSGFYFGGE 587
[210][TOP]
>UniRef100_C0W593 DNA topoisomerase n=1 Tax=Actinomyces urogenitalis DSM 15434
RepID=C0W593_9ACTO
Length = 931
Score = 103 bits (256), Expect = 1e-20
Identities = 65/153 (42%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +2
Query: 23 AMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRP 202
A + G ++ LP + G+ + + H TTPP RYT+ASLVK LE +GRP
Sbjct: 477 AEPGKAGAASAGEVRLPAMEVGDVLDAKVAEASGHETTPPPRYTEASLVKALEEREIGRP 536
Query: 203 STYASIVETLVLRGYVS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTA 379
STYA+ + T+ RGYV RG QAL P AF V +LL F VD FTA
Sbjct: 537 STYAATMSTIADRGYVEHRG----------QALVPTWLAFAVTRLLEENFSELVDYDFTA 586
Query: 380 EMERSLDAIAAGAADRQEYLSSYYLG-SDGLAA 475
ME LD IAAG DR +L+ +Y G DG A
Sbjct: 587 SMEADLDRIAAGEEDRVAWLTRFYYGDGDGQGA 619
[211][TOP]
>UniRef100_B7RUB0 DNA topoisomerase n=1 Tax=marine gamma proteobacterium HTCC2148
RepID=B7RUB0_9GAMM
Length = 882
Score = 103 bits (256), Expect = 1e-20
Identities = 60/143 (41%), Positives = 80/143 (55%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLPDV G+ +A+ LD V+H T P RY +ASLV+ELE G+GRPSTYASI+ T+ RG
Sbjct: 461 VLPDVNEGDVLALKKLDPVQHFTKPTPRYGEASLVRELEKRGIGRPSTYASIISTIQDRG 520
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
Y RL + +V Q L++ FP +D FTA ME LD +A G D
Sbjct: 521 Y---------ARLENKRFYAEKMGDIVTQRLQKSFPDLLDYGFTAGMEERLDDVADGDRD 571
Query: 425 RQEYLSSYYLGSDGLAASVARME 493
++ L ++Y GL + A E
Sbjct: 572 WRDLLDAFYAEFSGLLEAAAEPE 594
[212][TOP]
>UniRef100_UPI00017F3007 DNA topoisomerase I (topA) n=1 Tax=Borrelia burgdorferi 80a
RepID=UPI00017F3007
Length = 848
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[213][TOP]
>UniRef100_B7J0S2 DNA topoisomerase n=1 Tax=Borrelia burgdorferi ZS7
RepID=B7J0S2_BORBZ
Length = 848
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[214][TOP]
>UniRef100_A7I3J1 DNA topoisomerase n=1 Tax=Campylobacter hominis ATCC BAA-381
RepID=A7I3J1_CAMHC
Length = 689
Score = 102 bits (255), Expect = 1e-20
Identities = 55/130 (42%), Positives = 82/130 (63%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LPD G+ + V L VE+ T PPARY++ASL+K+LE+LG+GRPSTYA + L+ R
Sbjct: 423 KILPDFKIGDELKVQNLKSVENQTEPPARYSEASLIKKLESLGIGRPSTYAPTLSLLISR 482
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV+ ++ L P AF + ++L + F + VD+ FT++ME LD IA +A
Sbjct: 483 KYVNTEKKQ---------LVPTEIAFKIVEMLEQNFNNIVDSEFTSKMETKLDEIAEKSA 533
Query: 422 DRQEYLSSYY 451
D QE L+ +Y
Sbjct: 534 DWQEILADFY 543
[215][TOP]
>UniRef100_A4XIW7 DNA topoisomerase n=1 Tax=Caldicellulosiruptor saccharolyticus DSM
8903 RepID=A4XIW7_CALS8
Length = 693
Score = 102 bits (255), Expect = 1e-20
Identities = 58/148 (39%), Positives = 83/148 (56%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP++ GE + L+ +H T PP+RYT+A+L+K LE G+GRPSTYA ++T++ RGY
Sbjct: 432 LPEIFEGEMLKPIKLEKKQHFTQPPSRYTEATLIKALEEKGIGRPSTYAPTIQTILERGY 491
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + R L P VV +L+ YF +D FTAE+E +LD I G AD
Sbjct: 492 VVKEDR---------FLKPTELGKVVTNILKEYFKDIIDIEFTAELEENLDRIEEGKADW 542
Query: 428 QEYLSSYYLGSDGLAASVARMEKEIDTA 511
E + +YL +EKE++TA
Sbjct: 543 VEIVRKFYL----------PLEKELETA 560
[216][TOP]
>UniRef100_C0AM73 DNA topoisomerase n=1 Tax=Borrelia sp. SV1 RepID=C0AM73_9SPIO
Length = 850
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[217][TOP]
>UniRef100_C0ALV9 DNA topoisomerase n=1 Tax=Borrelia burgdorferi 94a
RepID=C0ALV9_BORBU
Length = 848
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[218][TOP]
>UniRef100_C0AJH7 DNA topoisomerase n=1 Tax=Borrelia burgdorferi 118a
RepID=C0AJH7_BORBU
Length = 848
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[219][TOP]
>UniRef100_O51768 DNA topoisomerase 1 n=6 Tax=Borrelia burgdorferi RepID=TOP1_BORBU
Length = 848
Score = 102 bits (255), Expect = 1e-20
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDTFSIVKMKTSEHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL +V ++E +ID++
Sbjct: 571 FYNGKKGLKDTVMQLEPKIDSS 592
[220][TOP]
>UniRef100_UPI0001B4FB50 DNA topoisomerase I n=1 Tax=Streptomyces hygroscopicus ATCC 53653
RepID=UPI0001B4FB50
Length = 964
Score = 102 bits (254), Expect = 2e-20
Identities = 61/137 (44%), Positives = 79/137 (57%), Gaps = 3/137 (2%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V G+ + + H T PPARYT+ASLVKELE +GRPSTYA+I+ T++ RGY
Sbjct: 479 LPQVAEGDGLTAEEITADGHATKPPARYTEASLVKELEEREIGRPSTYATILGTILDRGY 538
Query: 248 V-SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
V +GT AL P +F V LL ++F VD FTA+ME LD IA G A
Sbjct: 539 VFKKGT----------ALVPSFLSFAVVNLLEKHFGRLVDYDFTAKMEDDLDRIARGEAQ 588
Query: 425 RQEYLSSYYLG--SDGL 469
+L +Y G +DG+
Sbjct: 589 AVPWLKRFYFGESADGV 605
[221][TOP]
>UniRef100_C8PI89 DNA topoisomerase I n=1 Tax=Campylobacter gracilis RM3268
RepID=C8PI89_9PROT
Length = 743
Score = 102 bits (254), Expect = 2e-20
Identities = 51/130 (39%), Positives = 81/130 (62%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP + G+ +++ +L +H T PPARY++ASL+K+LE+LG+GRPSTYA + L R
Sbjct: 423 KILPSLSAGDAMSLQSLSSQQHFTEPPARYSEASLIKKLESLGIGRPSTYAPTISLLTAR 482
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV+ + + L P AF + ++L + F + VD+ FT++ME LD IA A
Sbjct: 483 NYVN---------IEQKHLVPSEIAFKITEMLEQNFKNIVDSEFTSKMEEKLDDIAENKA 533
Query: 422 DRQEYLSSYY 451
D Q+ L+ +Y
Sbjct: 534 DWQQILADFY 543
[222][TOP]
>UniRef100_A6DDI1 DNA topoisomerase n=1 Tax=Caminibacter mediatlanticus TB-2
RepID=A6DDI1_9PROT
Length = 725
Score = 102 bits (254), Expect = 2e-20
Identities = 57/132 (43%), Positives = 74/132 (56%)
Frame = +2
Query: 56 AAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLV 235
A +LP+ GE + + +H T PP RYT+ASL+K+LE+LG+GRPSTYA + L
Sbjct: 421 ADTLLPEFKEGEKLKPEEIKATQHFTKPPERYTEASLIKKLESLGIGRPSTYAPTITLLQ 480
Query: 236 LRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAG 415
R YV + + L P AF V + L ++FP VDA FTA ME LD IA G
Sbjct: 481 NRNYV---------EIKDKKLHPTEIAFNVIETLEKHFPDIVDAKFTANMEEMLDEIARG 531
Query: 416 AADRQEYLSSYY 451
D QE L +Y
Sbjct: 532 NKDWQEMLKEFY 543
[223][TOP]
>UniRef100_A9WTD8 DNA topoisomerase n=1 Tax=Renibacterium salmoninarum ATCC 33209
RepID=A9WTD8_RENSM
Length = 912
Score = 102 bits (253), Expect = 2e-20
Identities = 56/133 (42%), Positives = 80/133 (60%), Gaps = 1/133 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP++ + + + ++ + H T+PP RYT+ASLVK LE G+GRPSTYA+ + T++ RGY
Sbjct: 478 LPNLAAQDALTATEIEPLGHETSPPPRYTEASLVKTLEERGIGRPSTYAATISTIMDRGY 537
Query: 248 VS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
VS RG+ AL P AF V +LL +YF ++VD FTA ME LD I+ G
Sbjct: 538 VSQRGS----------ALVPSWVAFSVVRLLEQYFQNYVDYDFTAGMEEDLDRISRGEET 587
Query: 425 RQEYLSSYYLGSD 463
+L +Y G +
Sbjct: 588 GPHWLKLFYFGDE 600
[224][TOP]
>UniRef100_A3V7A4 DNA topoisomerase n=1 Tax=Loktanella vestfoldensis SKA53
RepID=A3V7A4_9RHOB
Length = 870
Score = 102 bits (253), Expect = 2e-20
Identities = 58/139 (41%), Positives = 81/139 (58%)
Frame = +2
Query: 35 RPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYA 214
R T+ + LP + GE V ++D +H T PP RYT+A+LVK +E LG+GRPSTYA
Sbjct: 422 RDDTADDDDKRLPQLAQGEKVVKQSVDPEQHFTQPPPRYTEATLVKRMEELGIGRPSTYA 481
Query: 215 SIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERS 394
SIV T+ RGYV + RL PQ +TAF L YF ++ FTA++E
Sbjct: 482 SIVTTIQDRGYVEK----DKNRLIPQDKGRLVTAF-----LMNYFQKYIGYDFTADLENQ 532
Query: 395 LDAIAAGAADRQEYLSSYY 451
LD ++AG AD ++ L ++
Sbjct: 533 LDEVSAGNADYKKVLDRFW 551
[225][TOP]
>UniRef100_A8SI18 DNA topoisomerase n=1 Tax=Faecalibacterium prausnitzii M21/2
RepID=A8SI18_9FIRM
Length = 694
Score = 101 bits (252), Expect = 3e-20
Identities = 56/146 (38%), Positives = 85/146 (58%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ + + L + T PPARYT+A+L+K LE G+GRPSTYA I+ T++ RGY
Sbjct: 434 LPPLEQGQVLKLRELKSEQKFTQPPARYTEATLIKALEENGIGRPSTYAPIITTIIDRGY 493
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R ++ L P L VD L+ FP VD F+A+ME++LD + +G AD
Sbjct: 494 VERDQKK---------LKPTLLGRAVDGLMLEQFPHIVDVDFSAQMEKNLDKVESGKADW 544
Query: 428 QEYLSSYYLGSDGLAASVARMEKEID 505
++ + +Y G AS+ + EK ++
Sbjct: 545 RKTVDDFY---QGFEASLEQAEKNME 567
[226][TOP]
>UniRef100_A3THV4 DNA topoisomerase n=1 Tax=Janibacter sp. HTCC2649
RepID=A3THV4_9MICO
Length = 942
Score = 101 bits (252), Expect = 3e-20
Identities = 60/141 (42%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G + V + H T+PPARYT+A+LVK +E G+GRPSTYAS + T+ RGY
Sbjct: 472 LPRMGEGTELKVIRAEADGHDTSPPARYTEATLVKAMEEKGIGRPSTYASTIGTIQDRGY 531
Query: 248 VS-RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
VS RG AL P AF V +L+ +F VD FTA ME LD IA G A
Sbjct: 532 VSNRG----------NALVPSWLAFAVTRLMEEHFTRLVDYDFTASMEEDLDQIANGDAQ 581
Query: 425 RQEYLSSYYLGSDGLAASVAR 487
R +L +Y G + ++ R
Sbjct: 582 RATWLKRFYFGDEATSSEGLR 602
[227][TOP]
>UniRef100_Q7UMV5 DNA topoisomerase n=1 Tax=Rhodopirellula baltica RepID=Q7UMV5_RHOBA
Length = 936
Score = 101 bits (251), Expect = 4e-20
Identities = 55/134 (41%), Positives = 80/134 (59%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP V + ++V+ LD HTT PP+R+++ASL + LE G+GRPSTYASI++T+ R
Sbjct: 487 RLLPAVNENDGLSVATLDPKSHTTQPPSRFSEASLTRTLEEKGIGRPSTYASIIDTIQRR 546
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV + AL P TAF V +L+ +F VD FTA+ME LD I+ A
Sbjct: 547 DYVYK---------KGNALVPSWTAFSVIRLMETHFEPLVDYDFTAQMEDFLDTISRQEA 597
Query: 422 DRQEYLSSYYLGSD 463
+ +YL +Y G +
Sbjct: 598 ESLQYLKRFYFGDE 611
[228][TOP]
>UniRef100_A5UT75 DNA topoisomerase I n=1 Tax=Roseiflexus sp. RS-1 RepID=A5UT75_ROSS1
Length = 789
Score = 101 bits (251), Expect = 4e-20
Identities = 58/128 (45%), Positives = 76/128 (59%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + G+ +A+ L V+H T PP R+T+ASLVKELE LG+GRPSTYA + T++ R Y
Sbjct: 453 LPLLAEGDVLALVQLLPVQHFTEPPPRFTEASLVKELERLGIGRPSTYAPTISTIIEREY 512
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V L + L P VV LL ++FPS VD FT+EME+ LD IA G +
Sbjct: 513 V---------ELADKKLVPTTLGRVVTDLLVQHFPSIVDYGFTSEMEQQLDDIAEGEKEW 563
Query: 428 QEYLSSYY 451
L S+Y
Sbjct: 564 TPVLRSFY 571
[229][TOP]
>UniRef100_B0MRI8 DNA topoisomerase n=1 Tax=Eubacterium siraeum DSM 15702
RepID=B0MRI8_9FIRM
Length = 713
Score = 101 bits (251), Expect = 4e-20
Identities = 58/146 (39%), Positives = 82/146 (56%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP + GE + V L +H T PP RYT+ASL+K LE G+GRPSTYA + T++ R Y
Sbjct: 447 LPALEVGEKLKVKELTGNQHFTQPPPRYTEASLIKALEENGIGRPSTYAPTIATILDRHY 506
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R ++ L P V+ L++ +F VDA FTA+ME LD I AG AD
Sbjct: 507 VEREAKQ---------LKPTSLGIVITDLMKGHFERIVDAKFTAQMESDLDKIEAGKADW 557
Query: 428 QEYLSSYYLGSDGLAASVARMEKEID 505
+ L +Y G D + + + EK+++
Sbjct: 558 VDVLGKFYTGFDKM---LTKAEKDME 580
[230][TOP]
>UniRef100_Q3AB70 DNA topoisomerase n=1 Tax=Carboxydothermus hydrogenoformans Z-2901
RepID=Q3AB70_CARHZ
Length = 694
Score = 100 bits (250), Expect = 5e-20
Identities = 57/146 (39%), Positives = 85/146 (58%), Gaps = 1/146 (0%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP ++ G+ + + L+ +H T PP RYT+A+L+K LE G+GRPSTYA I+ET++ RGY
Sbjct: 432 LPALMEGQSLTLLKLEPKQHFTEPPPRYTEATLIKALEEKGIGRPSTYAPILETILKRGY 491
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + ++ L P +V LL+ +FP +D FTAEME LD I G +
Sbjct: 492 VEKDKKQ---------LKPTELGRIVVDLLKEHFPDIIDVEFTAEMEEKLDQIEEGEKNW 542
Query: 428 QEYLSSYYLG-SDGLAASVARMEKEI 502
E L ++Y ++ L S ++EK I
Sbjct: 543 IEVLRNFYEPFNETLRQSYEKIEKII 568
[231][TOP]
>UniRef100_C1WT22 DNA topoisomerase n=1 Tax=Kribbella flavida DSM 17836
RepID=C1WT22_9ACTO
Length = 923
Score = 100 bits (250), Expect = 5e-20
Identities = 56/134 (41%), Positives = 77/134 (57%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
+PDV G+ + + + H T PP+R+T+A+L+ +LE +GRPSTYASI+ T+ RGY
Sbjct: 483 IPDVAEGDVLPATEVLASGHETKPPSRFTEATLIAQLEEREIGRPSTYASILGTIQARGY 542
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V + AL P AF V +LL ++F VD AFTA ME LD +AAG R
Sbjct: 543 VYK---------KGNALVPAWLAFAVVRLLEQHFTRLVDYAFTASMEDVLDDVAAGNLQR 593
Query: 428 QEYLSSYYLGSDGL 469
+ L +Y G D L
Sbjct: 594 EGVLGRFYFGDDDL 607
[232][TOP]
>UniRef100_Q5QWH4 DNA topoisomerase n=1 Tax=Idiomarina loihiensis RepID=Q5QWH4_IDILO
Length = 872
Score = 100 bits (249), Expect = 6e-20
Identities = 63/147 (42%), Positives = 86/147 (58%)
Frame = +2
Query: 11 VSSSAMSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALG 190
V A S + G +T LPDV G+ + + L+ +H T PPARY +ASLVKELE G
Sbjct: 443 VMPPASSKKDGDAT-----LPDVKKGDALQLEKLNPEQHFTKPPARYGEASLVKELEKRG 497
Query: 191 VGRPSTYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAA 370
+GRPSTYASI+ T+ RGYV +R + A ++ V D+L+ F ++
Sbjct: 498 IGRPSTYASIISTIQDRGYVRVESR--------RFFAEKMGEIVNDRLIEN-FTELMNYN 548
Query: 371 FTAEMERSLDAIAAGAADRQEYLSSYY 451
FTAEME++LD IAAG D +E L +Y
Sbjct: 549 FTAEMEQALDDIAAGKRDWKETLDKFY 575
[233][TOP]
>UniRef100_A8F3N1 DNA topoisomerase n=1 Tax=Thermotoga lettingae TMO
RepID=A8F3N1_THELT
Length = 722
Score = 100 bits (249), Expect = 6e-20
Identities = 52/124 (41%), Positives = 73/124 (58%)
Frame = +2
Query: 80 VPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRG 259
+P + +S + E T PPARYT+AS+V+ LE G+GRPSTYA+I+ TL+ R YV +
Sbjct: 421 IPSGEIRISKWQIEEDETKPPARYTEASMVRALEIRGIGRPSTYATIISTLLERKYVIKS 480
Query: 260 TRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYL 439
+ + L P + FVV+ L + FP VD FTA+ME +LD I G D +E L
Sbjct: 481 SNQ---------LIPTVMGFVVNHYLEKKFPEIVDLQFTAKMEEALDKIEQGQKDYKELL 531
Query: 440 SSYY 451
+Y
Sbjct: 532 RDFY 535
[234][TOP]
>UniRef100_C6P7P2 DNA topoisomerase n=1 Tax=Thermoanaerobacterium
thermosaccharolyticum DSM 571 RepID=C6P7P2_CLOTS
Length = 686
Score = 100 bits (249), Expect = 6e-20
Identities = 53/136 (38%), Positives = 75/136 (55%)
Frame = +2
Query: 44 TSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIV 223
T + LP + G+ + + L +H T PPARYT+A+L+KELE G+GRPSTYA I+
Sbjct: 425 TENIEEKTLPLLEKGDHLKLKVLKPEQHFTQPPARYTEATLIKELEEKGIGRPSTYAPII 484
Query: 224 ETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDA 403
TL+ RGYV + + L P F+V +++ +FP VD FTAEME LD
Sbjct: 485 STLLERGYVIKEKKN---------LKPTELGFIVTDVMKEFFPDIVDVKFTAEMEEQLDK 535
Query: 404 IAAGAADRQEYLSSYY 451
I G + + +Y
Sbjct: 536 IEEGIEKWCDVIDGFY 551
[235][TOP]
>UniRef100_A3WQ32 DNA topoisomerase n=1 Tax=Idiomarina baltica OS145
RepID=A3WQ32_9GAMM
Length = 872
Score = 100 bits (249), Expect = 6e-20
Identities = 58/128 (45%), Positives = 80/128 (62%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LPD+ GE +A+ L+ +H T PPARY++ASLVKELE G+GRPSTYASI+ T+ RGY
Sbjct: 457 LPDIGKGEILALQQLEPQQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGY 516
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
V R + A ++ V D+L+ F ++ FTAEME++LD IAAG +
Sbjct: 517 VKVENR--------RFFAEKMGEIVNDRLIEN-FTELMNYNFTAEMEQALDDIAAGKRNW 567
Query: 428 QEYLSSYY 451
+E L +Y
Sbjct: 568 KETLDKFY 575
[236][TOP]
>UniRef100_B8CW42 DNA topoisomerase n=1 Tax=Halothermothrix orenii H 168
RepID=B8CW42_HALOH
Length = 691
Score = 100 bits (248), Expect = 8e-20
Identities = 54/129 (41%), Positives = 71/129 (55%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LP V E + V + +H T PP RYT+A+LVK LE G+GRPSTYA I+ T++ RG
Sbjct: 431 ILPPVKKSERLDVKEIKPEQHFTQPPPRYTEATLVKTLEEEGIGRPSTYAPIISTIISRG 490
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV R ++ L P F+V LL +YFP D FTA ME LD I G +
Sbjct: 491 YVERQGKQ---------LKPTELGFIVTDLLSKYFPDVTDIEFTAHMEERLDKIEDGKDE 541
Query: 425 RQEYLSSYY 451
+ L +Y
Sbjct: 542 WRNVLEDFY 550
[237][TOP]
>UniRef100_A4J5Z9 DNA topoisomerase n=1 Tax=Desulfotomaculum reducens MI-1
RepID=A4J5Z9_DESRM
Length = 710
Score = 100 bits (248), Expect = 8e-20
Identities = 55/129 (42%), Positives = 72/129 (55%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLP++ G+ V L +H T PP RYTDA+LVK LE G+GRPSTYA IVET+ RG
Sbjct: 433 VLPELAKGDKVQAKDLTPKQHFTQPPPRYTDATLVKVLEEKGIGRPSTYAPIVETIQRRG 492
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV R ++ P +V LL+ +FP ++ FTA+ME+ LD IA G
Sbjct: 493 YVVRENKQ---------FYPTELGVIVVDLLKNHFPEIINVEFTADMEKKLDQIAEGEQQ 543
Query: 425 RQEYLSSYY 451
L +Y
Sbjct: 544 WAGVLRDFY 552
[238][TOP]
>UniRef100_C8PW91 DNA topoisomerase I (Fragment) n=1 Tax=Enhydrobacter aerosaccus
SK60 RepID=C8PW91_9GAMM
Length = 754
Score = 100 bits (248), Expect = 8e-20
Identities = 54/129 (41%), Positives = 79/129 (61%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
+LPDV GE + V +++ +H T PPARYT+ASLVKELE G+GRPSTYA+I+ T+ RG
Sbjct: 500 LLPDVKIGEKLVVDSIEPTQHFTKPPARYTEASLVKELEKRGIGRPSTYAAIISTIQERG 559
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV + + A ++ V D+L+ FP +D FTA +E +LD +A G +
Sbjct: 560 YVKVENK--------RLFAEKMGDIVTDRLVNS-FPHLMDYTFTAGLEENLDEVAEGQQN 610
Query: 425 RQEYLSSYY 451
++ L +Y
Sbjct: 611 WKKVLDDFY 619
[239][TOP]
>UniRef100_Q4FR50 DNA topoisomerase n=1 Tax=Psychrobacter arcticus 273-4
RepID=Q4FR50_PSYA2
Length = 892
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/133 (42%), Positives = 74/133 (55%)
Frame = +2
Query: 53 TAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETL 232
T +LPDV G+ + V LD +H T PP RYT+ASLVKELE G+GRPSTYASI+ T+
Sbjct: 474 TDDNLLPDVKKGDKLTVDKLDPSQHFTKPPPRYTEASLVKELEKKGIGRPSTYASIISTI 533
Query: 233 VLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
RGYV + + RLTA FP +D FTA +E LD +A
Sbjct: 534 QDRGYVKLENKRLFAEKMGDIVTDRLTA---------SFPDLMDYTFTAALEDKLDHVAE 584
Query: 413 GAADRQEYLSSYY 451
G + ++ L ++Y
Sbjct: 585 GDTNWKDVLDNFY 597
[240][TOP]
>UniRef100_Q317I9 DNA topoisomerase n=1 Tax=Desulfovibrio desulfuricans subsp.
desulfuricans str. G20 RepID=Q317I9_DESDG
Length = 747
Score = 99.8 bits (247), Expect = 1e-19
Identities = 58/159 (36%), Positives = 87/159 (54%)
Frame = +2
Query: 26 MSARPGTSTTAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPS 205
M+A P ++ A LP + G+ + ++ L+ + T PPARY++ASLV+E+E G+GRPS
Sbjct: 416 MAAAPASAKEANVELPPMQQGQTLELTLLEKEQKFTQPPARYSEASLVREMEEKGIGRPS 475
Query: 206 TYASIVETLVLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEM 385
TYASI+ T+V R Y RL + P FVV +L +F + +D FTA+M
Sbjct: 476 TYASIISTIVDRDYT---------RLEEKHFVPTDLGFVVCDMLTNHFGTLMDIGFTAQM 526
Query: 386 ERSLDAIAAGAADRQEYLSSYYLGSDGLAASVARMEKEI 502
E SLD +A G D + + + AS A+ K +
Sbjct: 527 ENSLDKVAEGDLDWVALMKDFTSDFNPTLASAAKEMKTV 565
[241][TOP]
>UniRef100_Q30U79 DNA topoisomerase n=1 Tax=Sulfurimonas denitrificans DSM 1251
RepID=Q30U79_SULDN
Length = 743
Score = 99.8 bits (247), Expect = 1e-19
Identities = 51/130 (39%), Positives = 78/130 (60%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP + G+ + ++ +H T PPARY++A+L+K+LE+ G+GRPSTYA + TL R
Sbjct: 425 KLLPSLSEGQSAQIQKIESTQHFTEPPARYSEAALIKKLESEGIGRPSTYAPTIATLSNR 484
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV+ + + + P AF V ++L + F + VD +FTA ME LD IA G
Sbjct: 485 TYVT---------IEKKQIIPTEMAFTVTEILEKNFSNIVDLSFTANMEEKLDEIAEGQN 535
Query: 422 DRQEYLSSYY 451
D Q+ LS +Y
Sbjct: 536 DWQKLLSDFY 545
[242][TOP]
>UniRef100_Q11IM5 DNA topoisomerase n=1 Tax=Chelativorans sp. BNC1 RepID=Q11IM5_MESSB
Length = 849
Score = 99.8 bits (247), Expect = 1e-19
Identities = 54/128 (42%), Positives = 83/128 (64%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP++ GE + +++++ +HTT PP RY++ASL+K+LE LG+GRPSTYA+I++TL RGY
Sbjct: 444 LPEINSGEALKRNSVNVTKHTTEPPPRYSEASLIKKLEELGIGRPSTYAAILKTLDDRGY 503
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
VS R +L PQA +TAF L +F +V+ FTA++E LD I+ G
Sbjct: 504 VSNERR----KLVPQAKGRIVTAF-----LENFFRRYVEYDFTADLEEKLDEISDGKLSW 554
Query: 428 QEYLSSYY 451
++ L ++
Sbjct: 555 KQVLRDFW 562
[243][TOP]
>UniRef100_C6ADW8 DNA topoisomerase n=1 Tax=Bartonella grahamii as4aup
RepID=C6ADW8_BARGA
Length = 857
Score = 99.8 bits (247), Expect = 1e-19
Identities = 57/143 (39%), Positives = 86/143 (60%)
Frame = +2
Query: 68 LPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGY 247
LP V GE + ++ V+HTT PP+RY++ASL+K+LE LG+GRPSTYAS + TL RGY
Sbjct: 445 LPQVNTGEALTKEKVESVQHTTEPPSRYSEASLIKKLEELGIGRPSTYASTLATLCDRGY 504
Query: 248 VSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADR 427
+ R +L P A +TAF L +F +V+ FTA++E LD I+ G
Sbjct: 505 IVIDKR----KLIPDAKGRIVTAF-----LENFFNRYVEYGFTADLEEKLDLISDGKLSW 555
Query: 428 QEYLSSYYLGSDGLAASVARMEK 496
++ L ++ DG AS++ +++
Sbjct: 556 KDVLRDFW---DGFNASISNIQE 575
[244][TOP]
>UniRef100_B5YKX8 DNA topoisomerase n=1 Tax=Thermodesulfovibrio yellowstonii DSM
11347 RepID=B5YKX8_THEYD
Length = 777
Score = 99.8 bits (247), Expect = 1e-19
Identities = 54/129 (41%), Positives = 74/129 (57%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLP + + +S L+ +HTT PP RYT+A+LVK LE G+GRPSTYA+I+ T+ RG
Sbjct: 446 VLPQLNEKTSLKISELEAQKHTTEPPPRYTEATLVKALEEKGIGRPSTYATILSTIQERG 505
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV + Q L P FVV+ LL FP +D +FTA+ME LD I+ A
Sbjct: 506 YVKK---------VKQKLQPTYLGFVVNDLLEEKFPELMDYSFTAKMEEDLDKISLNEAK 556
Query: 425 RQEYLSSYY 451
+ + +Y
Sbjct: 557 WNKVIEEFY 565
[245][TOP]
>UniRef100_C8NEN6 DNA topoisomerase n=1 Tax=Granulicatella adiacens ATCC 49175
RepID=C8NEN6_9LACT
Length = 690
Score = 99.8 bits (247), Expect = 1e-19
Identities = 51/129 (39%), Positives = 78/129 (60%)
Frame = +2
Query: 65 VLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRG 244
VLP++ G+ V ++ L+ +H T PPARY++A+L+K LE +GVGRPSTYA +ET+ R
Sbjct: 431 VLPEMQVGDEVQLAKLNPEQHFTQPPARYSEATLIKTLEEIGVGRPSTYAPTIETIQKRY 490
Query: 245 YVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAAD 424
YV +L + P +VV Q++ +YFP+ VD FTA ME +LD + G +
Sbjct: 491 YV---------KLVSKRFEPTELGYVVHQIIEQYFPNIVDTHFTASMEDNLDLVEEGKEE 541
Query: 425 RQEYLSSYY 451
+ + +Y
Sbjct: 542 WVQVIDKFY 550
[246][TOP]
>UniRef100_B9L7D9 DNA topoisomerase n=1 Tax=Nautilia profundicola AmH
RepID=B9L7D9_NAUPA
Length = 728
Score = 99.4 bits (246), Expect = 1e-19
Identities = 55/133 (41%), Positives = 74/133 (55%)
Frame = +2
Query: 53 TAAQVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETL 232
+A +LP+ GE + + +H T PP RYT+ASL+K+LE+LG+GRPSTYA + L
Sbjct: 420 SANTLLPEFEKGEKLKPEDVKATQHFTKPPERYTEASLIKKLESLGIGRPSTYAPTITLL 479
Query: 233 VLRGYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAA 412
R YV + + L P AF V + L ++FP VDA FTA ME LD +A
Sbjct: 480 QNRNYV---------EVKDKKLHPTEIAFSVIETLEKHFPDIVDANFTANMEEMLDEVAE 530
Query: 413 GAADRQEYLSSYY 451
D QE L +Y
Sbjct: 531 AKKDWQEVLKDFY 543
[247][TOP]
>UniRef100_A9BI47 DNA topoisomerase n=1 Tax=Petrotoga mobilis SJ95 RepID=A9BI47_PETMO
Length = 762
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/126 (42%), Positives = 69/126 (54%)
Frame = +2
Query: 74 DVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVS 253
++ + + L E T PP RYT+A+L+KELE+ G+GRPSTYA+I+ TL+ R YVS
Sbjct: 439 EIGKNDKITYDQLKFEEKETNPPNRYTEATLIKELESKGIGRPSTYATIISTLLQRKYVS 498
Query: 254 RGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQE 433
+ + T L P T FVV L YFP VD FTA ME LD I G +
Sbjct: 499 KIAKST--------LRPTTTGFVVTDFLETYFPEIVDVKFTANMEEDLDKIEDGKNKSKV 550
Query: 434 YLSSYY 451
L +Y
Sbjct: 551 VLEQFY 556
[248][TOP]
>UniRef100_C4BX51 DNA topoisomerase n=1 Tax=Sebaldella termitidis ATCC 33386
RepID=C4BX51_9FUSO
Length = 746
Score = 99.4 bits (246), Expect = 1e-19
Identities = 55/152 (36%), Positives = 85/152 (55%)
Frame = +2
Query: 71 PDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYV 250
P++ G+ + V L++ + T PPAR++++SLVK+LEA G+GRPSTYASI+ETL R Y
Sbjct: 425 PEIKEGDELVVKELNIKDGMTKPPARFSESSLVKKLEAEGIGRPSTYASIIETLKTRNY- 483
Query: 251 SRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQ 430
L + P + + V L ++F ++ FTA ME LD I G+ +
Sbjct: 484 --------AELVDKRFIPTVLGYEVKSELEKHFEKIMNIKFTANMEEELDEIENGSIKWE 535
Query: 431 EYLSSYYLGSDGLAASVARMEKEIDTAWARRL 526
E ++++Y GL + + EKEI RR+
Sbjct: 536 ELMANFY---KGLEVDLTKFEKEIQDLQDRRI 564
[249][TOP]
>UniRef100_B9X7M3 DNA topoisomerase n=1 Tax=Borrelia spielmanii A14S
RepID=B9X7M3_9SPIO
Length = 849
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/142 (37%), Positives = 81/142 (57%)
Frame = +2
Query: 86 GEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLRGYVSRGTR 265
G+ ++ + EH T P RYT+ASLV+++E G+GRPSTY++I+ TL+ R Y +
Sbjct: 460 GDMFSIIQMRTSEHETKAPLRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYAFKLNN 519
Query: 266 ETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAADRQEYLSS 445
L P + V LL +YFP ++ FT+ ME LD IA G D+ +YLS
Sbjct: 520 ---------TLIPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSK 570
Query: 446 YYLGSDGLAASVARMEKEIDTA 511
+Y G GL V ++E +I+++
Sbjct: 571 FYNGKKGLKDIVMQLEPKINSS 592
[250][TOP]
>UniRef100_B6BGF4 DNA topoisomerase n=1 Tax=Campylobacterales bacterium GD 1
RepID=B6BGF4_9PROT
Length = 741
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/130 (40%), Positives = 78/130 (60%)
Frame = +2
Query: 62 QVLPDVVPGEPVAVSALDLVEHTTTPPARYTDASLVKELEALGVGRPSTYASIVETLVLR 241
++LP + GE + ++ +H T PPARY++ASL+K+LE+ GVGRPSTYA + TL R
Sbjct: 425 KLLPTLKEGEKAEIQTINPEQHFTEPPARYSEASLIKKLESEGVGRPSTYAPTIATLSGR 484
Query: 242 GYVSRGTRETAGRLPPQALAPRLTAFVVDQLLRRYFPSFVDAAFTAEMERSLDAIAAGAA 421
YV+ + + + P AF V ++L + F + VD +FTA ME LD I+ G
Sbjct: 485 TYVT---------IEKKQIIPTEIAFTVTEMLEKNFANIVDISFTANMEEKLDEISEGEN 535
Query: 422 DRQEYLSSYY 451
D Q+ LS +Y
Sbjct: 536 DWQKLLSDFY 545