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[1][TOP]
>UniRef100_Q6Z702 Os02g0125100 protein n=2 Tax=Oryza sativa RepID=Q6Z702_ORYSJ
Length = 514
Score = 300 bits (769), Expect = 3e-80
Identities = 142/181 (78%), Positives = 157/181 (86%), Gaps = 2/181 (1%)
Frame = +3
Query: 6 ISTPRPASTAPGV--KIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGT 179
++TP A AP + + MT+TEKILA+A+ER S+ PG+N+WV+ DVLMTHDVCGPGT
Sbjct: 52 VATPARAPRAPSSTGSVKSAMTMTEKILARASERASLEPGENVWVDVDVLMTHDVCGPGT 111
Query: 180 IGVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDR 359
IG+FKREFGEDAKVWD EKVVIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D
Sbjct: 112 IGIFKREFGEDAKVWDREKVVIIPDHYIFTSDERANRNVDILRDFCMEQNIKYFYDIKDL 171
Query: 360 SDYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGT 539
S++KANPDYKGVCHVALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFVMGT
Sbjct: 172 SNFKANPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGT 231
Query: 540 G 542
G
Sbjct: 232 G 232
[2][TOP]
>UniRef100_C4JBG7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4JBG7_MAIZE
Length = 505
Score = 300 bits (767), Expect = 6e-80
Identities = 141/177 (79%), Positives = 156/177 (88%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
TPR S+ VK T MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPGTIG+F
Sbjct: 49 TPRAPSSTGSVK--TAMTMTEKILARASERAALEPGENVWVDIDVLMTHDVCGPGTIGIF 106
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFGEDAKVWD EKVVIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D SD++
Sbjct: 107 KKEFGEDAKVWDREKVVIIPDHYIFTSDERANRNVDILRDFCLEQNIKYFYDIKDLSDFR 166
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCH+ALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFVMGTG
Sbjct: 167 ANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 223
[3][TOP]
>UniRef100_C4IZQ5 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=C4IZQ5_MAIZE
Length = 505
Score = 300 bits (767), Expect = 6e-80
Identities = 141/177 (79%), Positives = 156/177 (88%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
TPR S+ VK T MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPGTIG+F
Sbjct: 49 TPRAPSSTGSVK--TAMTMTEKILARASERAALEPGENVWVDIDVLMTHDVCGPGTIGIF 106
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFGEDAKVWD EKVVIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D SD++
Sbjct: 107 KKEFGEDAKVWDREKVVIIPDHYIFTSDERANRNVDILRDFCLEQNIKYFYDIKDLSDFR 166
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCH+ALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFVMGTG
Sbjct: 167 ANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 223
[4][TOP]
>UniRef100_B6TYJ6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6TYJ6_MAIZE
Length = 492
Score = 300 bits (767), Expect = 6e-80
Identities = 141/177 (79%), Positives = 156/177 (88%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
TPR S+ VK T MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPGTIG+F
Sbjct: 49 TPRAPSSTGSVK--TAMTMTEKILARASERAALEPGENVWVDIDVLMTHDVCGPGTIGIF 106
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFGEDAKVWD EKVVIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D SD++
Sbjct: 107 KKEFGEDAKVWDREKVVIIPDHYIFTSDERANRNVDILRDFCLEQNIKYFYDIKDLSDFR 166
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCH+ALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFVMGTG
Sbjct: 167 ANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 223
[5][TOP]
>UniRef100_B8LQ24 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQ24_PICSI
Length = 516
Score = 296 bits (757), Expect = 8e-79
Identities = 136/182 (74%), Positives = 155/182 (85%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 VISTPRPASTAPGV--KIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPG 176
V++ P+P +P + MT+TEKILA+AAER V PG+N+WV D LMTHDVCGPG
Sbjct: 54 VMAPPQPQQRSPASTGSVKHAMTMTEKILARAAERSQVSPGENVWVKVDNLMTHDVCGPG 113
Query: 177 TIGVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITD 356
TIG+FK+EFG AKVWD EK+VIIPDHYIFT D RANRNVDI+RDF EQ IKYFYDITD
Sbjct: 114 TIGIFKKEFGSQAKVWDREKIVIIPDHYIFTSDERANRNVDIIRDFALEQNIKYFYDITD 173
Query: 357 RSDYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMG 536
RSD++ANPDYKGVCH+ALAQEGH RPGEVLFGTDSHTCNAGAFGQFA+GIGN+DAGF+MG
Sbjct: 174 RSDFRANPDYKGVCHIALAQEGHCRPGEVLFGTDSHTCNAGAFGQFASGIGNTDAGFIMG 233
Query: 537 TG 542
TG
Sbjct: 234 TG 235
[6][TOP]
>UniRef100_C5XT62 Putative uncharacterized protein Sb04g002120 n=1 Tax=Sorghum
bicolor RepID=C5XT62_SORBI
Length = 507
Score = 295 bits (756), Expect = 1e-78
Identities = 140/176 (79%), Positives = 155/176 (88%)
Frame = +3
Query: 15 PRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFK 194
PR S+ VK A MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPGTIG+FK
Sbjct: 52 PRAPSSTGSVKSA--MTMTEKILARASERAALEPGENVWVDVDVLMTHDVCGPGTIGIFK 109
Query: 195 REFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKA 374
+EFGEDAKVWD EKVVIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D S++KA
Sbjct: 110 KEFGEDAKVWDREKVVIIPDHYIFTTDERANRNVDILRDFCLEQNIKYFYDIKDLSNFKA 169
Query: 375 NPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
NPDYKGVCHVALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFV+GTG
Sbjct: 170 NPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVLGTG 225
[7][TOP]
>UniRef100_B8LQY6 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=B8LQY6_PICSI
Length = 515
Score = 295 bits (755), Expect = 1e-78
Identities = 135/182 (74%), Positives = 155/182 (85%), Gaps = 2/182 (1%)
Frame = +3
Query: 3 VISTPRPASTAPGV--KIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPG 176
V++ P+P +P + MT+TEKILA+AAE+ V PG+N+WV D LMTHDVCGPG
Sbjct: 53 VMAPPQPQQRSPASTGSVKHAMTMTEKILARAAEKSQVNPGENVWVKVDNLMTHDVCGPG 112
Query: 177 TIGVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITD 356
TIG+FK+EFG AKVWD EK+VIIPDHYIFT D RANRNVDI+RDF EQ IKYFYDITD
Sbjct: 113 TIGIFKKEFGSQAKVWDREKIVIIPDHYIFTSDERANRNVDIIRDFALEQNIKYFYDITD 172
Query: 357 RSDYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMG 536
RSD++ANPDYKGVCH+ALAQEGH RPGEVLFGTDSHTCNAGAFGQFA+GIGN+DAGF+MG
Sbjct: 173 RSDFRANPDYKGVCHIALAQEGHCRPGEVLFGTDSHTCNAGAFGQFASGIGNTDAGFIMG 232
Query: 537 TG 542
TG
Sbjct: 233 TG 234
[8][TOP]
>UniRef100_A9TGU1 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9TGU1_PHYPA
Length = 518
Score = 292 bits (748), Expect = 9e-78
Identities = 135/174 (77%), Positives = 152/174 (87%)
Frame = +3
Query: 21 PASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKRE 200
PAST + MT TEKILA A+E+ + PG+N+WV DVLMTHDVCGPGTIG+FK+E
Sbjct: 67 PASTGA---VKQAMTATEKILANASEKTKLAPGENVWVKADVLMTHDVCGPGTIGIFKKE 123
Query: 201 FGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANP 380
FG++AKVWD EK+V+IPDHYIFT D RANRNVDILRDF EQ IKYFYDITDRS+++ANP
Sbjct: 124 FGQNAKVWDREKIVLIPDHYIFTSDERANRNVDILRDFAREQDIKYFYDITDRSNFRANP 183
Query: 381 DYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
DYKGVCHVALAQEGH RPGEVLFGTDSHTCNAGAFGQFATGIGN+DAGF+MGTG
Sbjct: 184 DYKGVCHVALAQEGHCRPGEVLFGTDSHTCNAGAFGQFATGIGNTDAGFIMGTG 237
[9][TOP]
>UniRef100_Q111B2 Homoaconitate hydratase family protein n=1 Tax=Trichodesmium
erythraeum IMS101 RepID=Q111B2_TRIEI
Length = 439
Score = 290 bits (743), Expect = 3e-77
Identities = 132/161 (81%), Positives = 147/161 (91%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILAKA+ + +V PG+NIWVN DVLMTHDVCGPGTIG+FKREFGE+AKVWD EK+
Sbjct: 3 MTMVEKILAKASGKSTVNPGENIWVNVDVLMTHDVCGPGTIGIFKREFGENAKVWDKEKI 62
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V+IPDHYIFT D RANRNVDILRDF EQ IKYFYDI +RS++KANPDYKGVCHVALAQE
Sbjct: 63 VLIPDHYIFTADERANRNVDILRDFAQEQNIKYFYDIIERSNFKANPDYKGVCHVALAQE 122
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GHTRPGEVLFGTDSHTCNAGAFG+FATGIGN+DA F+ GTG
Sbjct: 123 GHTRPGEVLFGTDSHTCNAGAFGEFATGIGNTDAAFIAGTG 163
[10][TOP]
>UniRef100_B9HSU8 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HSU8_POPTR
Length = 462
Score = 290 bits (742), Expect = 5e-77
Identities = 134/178 (75%), Positives = 154/178 (86%)
Frame = +3
Query: 9 STPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGV 188
S RPA+T + T +T+TEKI A+A+E+ + PG+N+WVN D+LMTHDVCGPG+IG+
Sbjct: 6 SERRPATTG---SVKTALTMTEKIFARASEKPQLIPGENVWVNVDILMTHDVCGPGSIGI 62
Query: 189 FKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDY 368
FK+EFG+DAKVWD EKVVIIPDHYIFT+D RANRNVDILRDF NEQ IKYFYDI D ++
Sbjct: 63 FKKEFGQDAKVWDREKVVIIPDHYIFTKDERANRNVDILRDFCNEQNIKYFYDIKDLGNF 122
Query: 369 KANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
KANPDYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 123 KANPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 180
[11][TOP]
>UniRef100_B6U6T6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Zea mays
RepID=B6U6T6_MAIZE
Length = 504
Score = 286 bits (733), Expect = 5e-76
Identities = 134/180 (74%), Positives = 153/180 (85%)
Frame = +3
Query: 3 VISTPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTI 182
V S R S+ VK A MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPG
Sbjct: 45 VASPARALSSTGSVKSA--MTMTEKILARASERAALEPGENVWVDVDVLMTHDVCGPGAF 102
Query: 183 GVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRS 362
+FK+EFGEDA+VWD EK+V+IPDHYIFT D RANRNVDILRDF EQ IKYFYDI D S
Sbjct: 103 DIFKKEFGEDARVWDREKLVVIPDHYIFTSDDRANRNVDILRDFCAEQNIKYFYDIKDLS 162
Query: 363 DYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
D++ANPDYKGVCH+ALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFV+GTG
Sbjct: 163 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVLGTG 222
[12][TOP]
>UniRef100_B9SQS5 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS5_RICCO
Length = 510
Score = 285 bits (730), Expect = 1e-75
Identities = 131/174 (75%), Positives = 150/174 (86%)
Frame = +3
Query: 21 PASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKRE 200
PA+T + T MT+TEKILA+A+E+ + PG+N+WVN DVLMTHDVCGPG+IG+FKRE
Sbjct: 58 PATTG---SVKTAMTMTEKILARASEKSQLSPGENVWVNVDVLMTHDVCGPGSIGIFKRE 114
Query: 201 FGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANP 380
FG++A VWD EK+VIIPDHYIFT D RANRNVDILRDF EQ +KYFYDI D S++K NP
Sbjct: 115 FGQNATVWDREKIVIIPDHYIFTTDERANRNVDILRDFCQEQNVKYFYDIKDLSNFKVNP 174
Query: 381 DYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
DYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 175 DYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 228
[13][TOP]
>UniRef100_B4FG11 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FG11_MAIZE
Length = 505
Score = 284 bits (727), Expect = 3e-75
Identities = 133/180 (73%), Positives = 152/180 (84%)
Frame = +3
Query: 3 VISTPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTI 182
V S R S+ VK A MT+TEKILA+A+ER ++ PG+N+WV+ DVLMTHDVCGPG
Sbjct: 46 VASPARALSSTGSVKSA--MTMTEKILARASERAALEPGENVWVDVDVLMTHDVCGPGAF 103
Query: 183 GVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRS 362
+FK+EFGEDA+VWD EK+V+IPDHYIFT D RA RNVDILRDF EQ IKYFYDI D S
Sbjct: 104 DIFKKEFGEDARVWDREKLVVIPDHYIFTSDGRAKRNVDILRDFCAEQNIKYFYDIKDLS 163
Query: 363 DYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
D++ANPDYKGVCH+ALAQEGH RPGEVL GTDSHTCNAGAFGQFATGIGN+DAGFV+GTG
Sbjct: 164 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVLGTG 223
[14][TOP]
>UniRef100_Q94AR8 3-isopropylmalate dehydratase n=1 Tax=Arabidopsis thaliana
RepID=LEUC_ARATH
Length = 509
Score = 284 bits (726), Expect = 3e-75
Identities = 132/172 (76%), Positives = 147/172 (85%), Gaps = 2/172 (1%)
Frame = +3
Query: 33 APGV--KIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFG 206
+PG + T MT+TEKILA+A+E+ V PGDNIWVN DVLMTHDVCGPG G+FKREFG
Sbjct: 56 SPGTTGSVKTGMTMTEKILARASEKSLVVPGDNIWVNVDVLMTHDVCGPGAFGIFKREFG 115
Query: 207 EDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDY 386
E AKVWD EK+V+IPDHYIFT D RANRNVDI+R+ EQ IKYFYDITD ++KANPDY
Sbjct: 116 EKAKVWDPEKIVVIPDHYIFTADKRANRNVDIMREHCREQNIKYFYDITDLGNFKANPDY 175
Query: 387 KGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
KGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 176 KGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 227
[15][TOP]
>UniRef100_UPI0001983BAD PREDICTED: similar to Os02g0125100 n=1 Tax=Vitis vinifera
RepID=UPI0001983BAD
Length = 508
Score = 283 bits (725), Expect = 4e-75
Identities = 130/177 (73%), Positives = 151/177 (85%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
+PR ST VK T MT+TEKILA+A+++ + PG+N+WV+ D+LMTHDVCGPG+ G+F
Sbjct: 52 SPRSPSTTGSVK--TAMTMTEKILARASQKPQLSPGENVWVDVDILMTHDVCGPGSFGIF 109
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFG++AKVWD EK+VIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D ++K
Sbjct: 110 KKEFGQNAKVWDREKIVIIPDHYIFTNDERANRNVDILRDFCTEQNIKYFYDIKDLGNFK 169
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
NPDYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 170 VNPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 226
[16][TOP]
>UniRef100_A7QRJ3 Chromosome chr8 scaffold_150, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QRJ3_VITVI
Length = 424
Score = 283 bits (725), Expect = 4e-75
Identities = 130/177 (73%), Positives = 151/177 (85%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
+PR ST VK T MT+TEKILA+A+++ + PG+N+WV+ D+LMTHDVCGPG+ G+F
Sbjct: 6 SPRSPSTTGSVK--TAMTMTEKILARASQKPQLSPGENVWVDVDILMTHDVCGPGSFGIF 63
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFG++AKVWD EK+VIIPDHYIFT D RANRNVDILRDF EQ IKYFYDI D ++K
Sbjct: 64 KKEFGQNAKVWDREKIVIIPDHYIFTNDERANRNVDILRDFCTEQNIKYFYDIKDLGNFK 123
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
NPDYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 124 VNPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 180
[17][TOP]
>UniRef100_UPI0001983576 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983576
Length = 508
Score = 283 bits (723), Expect = 7e-75
Identities = 130/177 (73%), Positives = 153/177 (86%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
+PR ST+ VK T MT+TEKILA+A+E+ + PG+N+WVN D+LMTHDVCGPG+ G+F
Sbjct: 52 SPRSPSTSGSVK--TAMTMTEKILARASEKPQLSPGENVWVNVDLLMTHDVCGPGSFGIF 109
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFGE+AKVWD EK+VIIP+HYIFT+D RANRNVDILR+F EQ IKYFYDI D +++
Sbjct: 110 KKEFGENAKVWDREKIVIIPEHYIFTKDERANRNVDILREFCTEQNIKYFYDIKDLGNFR 169
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DA FV+GTG
Sbjct: 170 ANPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAAFVLGTG 226
[18][TOP]
>UniRef100_A7NXJ3 Chromosome chr5 scaffold_2, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7NXJ3_VITVI
Length = 507
Score = 283 bits (723), Expect = 7e-75
Identities = 130/177 (73%), Positives = 153/177 (86%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
+PR ST+ VK T MT+TEKILA+A+E+ + PG+N+WVN D+LMTHDVCGPG+ G+F
Sbjct: 69 SPRSPSTSGSVK--TAMTMTEKILARASEKPQLSPGENVWVNVDLLMTHDVCGPGSFGIF 126
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
K+EFGE+AKVWD EK+VIIP+HYIFT+D RANRNVDILR+F EQ IKYFYDI D +++
Sbjct: 127 KKEFGENAKVWDREKIVIIPEHYIFTKDERANRNVDILREFCTEQNIKYFYDIKDLGNFR 186
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCHVALAQEGH RPGEVL GTDSHTC AGAFGQFATGIGN+DA FV+GTG
Sbjct: 187 ANPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAAFVLGTG 243
[19][TOP]
>UniRef100_B9HKV5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9HKV5_POPTR
Length = 443
Score = 281 bits (719), Expect = 2e-74
Identities = 129/161 (80%), Positives = 142/161 (88%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI A+A+E V PG+N+WVN DVLMTHD+ GPG+IG+FKREFG DAKVWD EKV
Sbjct: 1 MTMTEKIFARASEEPQVSPGENVWVNVDVLMTHDISGPGSIGIFKREFGPDAKVWDREKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V+IPDHYIFTED ANRNVDILRDF N+Q IKYFYDI D +YKANPDYKGVCHVALAQE
Sbjct: 61 VVIPDHYIFTEDKLANRNVDILRDFCNDQDIKYFYDIKDLGNYKANPDYKGVCHVALAQE 120
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH RPGEVL GTDSHTC AGAFGQFATGIGN+DAGFV+GTG
Sbjct: 121 GHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 161
[20][TOP]
>UniRef100_A8JG03 Isopropylmalate dehydratase, large subunit n=1 Tax=Chlamydomonas
reinhardtii RepID=A8JG03_CHLRE
Length = 487
Score = 279 bits (714), Expect = 8e-74
Identities = 127/177 (71%), Positives = 149/177 (84%)
Frame = +3
Query: 12 TPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF 191
TP A ++ G + MT+TEKILA ++ +V+PGDNIW D LMTHDVCGPGT G+F
Sbjct: 31 TPARAPSSTG-SVKRAMTMTEKILANHSDNSAVKPGDNIWTKVDKLMTHDVCGPGTFGIF 89
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
++EFG +AKVWD E+VVIIPDHYIFT D RANRNVDILR+ + IKYFYDITDRS++K
Sbjct: 90 QKEFGPNAKVWDNERVVIIPDHYIFTSDARANRNVDILREVAGKYNIKYFYDITDRSNFK 149
Query: 372 ANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
ANPDYKGVCHVALAQEGH +PGEVLFGTDSHTCNAGAFGQFATG+GN+DAGF++GTG
Sbjct: 150 ANPDYKGVCHVALAQEGHCKPGEVLFGTDSHTCNAGAFGQFATGVGNTDAGFILGTG 206
[21][TOP]
>UniRef100_B9SQS6 3-isopropylmalate dehydratase, putative n=1 Tax=Ricinus communis
RepID=B9SQS6_RICCO
Length = 621
Score = 271 bits (692), Expect = 3e-71
Identities = 129/178 (72%), Positives = 149/178 (83%)
Frame = +3
Query: 9 STPRPASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGV 188
S +PA+T VK A MT TEKILA+A+E+ + PG+N+WVN D+LMTHDVCGPG+ +
Sbjct: 190 SERKPATTGSVVKNA--MTTTEKILARASEKPQLGPGENVWVNVDILMTHDVCGPGSFAI 247
Query: 189 FKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDY 368
FKREFGE+AKVWD EKVV+IPDHYIFT D ANRNVDILR+F EQ IK+FYDI D S++
Sbjct: 248 FKREFGENAKVWDHEKVVVIPDHYIFTADKLANRNVDILREFCLEQNIKHFYDIKDISNF 307
Query: 369 KANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
KAN DYKGVCH+ALAQEGH RPGEVL GTDSHTC AGAFGQFATGIG +DAGFV+GTG
Sbjct: 308 KANSDYKGVCHIALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGITDAGFVLGTG 365
[22][TOP]
>UniRef100_UPI00016C35D3 homoaconitate hydratase family protein n=1 Tax=Gemmata
obscuriglobus UQM 2246 RepID=UPI00016C35D3
Length = 435
Score = 253 bits (646), Expect = 6e-66
Identities = 115/161 (71%), Positives = 133/161 (82%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+A+ + PG+N+W N DVLMTHDVCGPGT GVFK+EFG DAKVWD EK+
Sbjct: 4 MTMTEKILARASGKAQAAPGENVWANVDVLMTHDVCGPGTFGVFKKEFGPDAKVWDKEKL 63
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V+IPDHYIFT+D ANRNVD+LR F EQ IKYFYD+ +S YKGVCH+AL +E
Sbjct: 64 VLIPDHYIFTKDAMANRNVDVLRQFAKEQDIKYFYDVGTKS-------YKGVCHIALPEE 116
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GHTRPGEVL GTDSHTC AGAFG+FATGIGN+DAGFV+GTG
Sbjct: 117 GHTRPGEVLLGTDSHTCTAGAFGEFATGIGNTDAGFVLGTG 157
[23][TOP]
>UniRef100_B9XBH0 Aconitate hydratase domain protein n=1 Tax=bacterium Ellin514
RepID=B9XBH0_9BACT
Length = 455
Score = 253 bits (646), Expect = 6e-66
Identities = 120/174 (68%), Positives = 137/174 (78%), Gaps = 13/174 (7%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILA+AA + V GDN+WV+ DVLMTHDVCGPGTIGVFKREFG+ AKVWD ++V
Sbjct: 1 MTLTEKILARAAGKAKVEAGDNVWVSADVLMTHDVCGPGTIGVFKREFGKTAKVWDKQRV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSD-------------YKANP 380
VIIPDHYIFT D ++NRNVDILRDFV EQG+ YFYD+ D D +
Sbjct: 61 VIIPDHYIFTADSKSNRNVDILRDFVREQGLPYFYDVIDNPDGNWVFDPSKGLLKKQYGS 120
Query: 381 DYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+Y GVCH AL Q+GHTRPGE+LFGTDSHTC AGAF +FATGIGN+DAGFVMGTG
Sbjct: 121 NYAGVCHTALPQKGHTRPGEILFGTDSHTCMAGAFNEFATGIGNTDAGFVMGTG 174
[24][TOP]
>UniRef100_B3E0P6 3-isopropylmalate dehydratase large subunit n=1
Tax=Methylacidiphilum infernorum V4 RepID=B3E0P6_METI4
Length = 455
Score = 243 bits (619), Expect = 8e-63
Identities = 116/174 (66%), Positives = 135/174 (77%), Gaps = 13/174 (7%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILAKA++R V PGDNIWV+ D+L+THDVCGPGTIGVF REFG+ A+VWD K+
Sbjct: 1 MTLTEKILAKASKRSRVSPGDNIWVDADILLTHDVCGPGTIGVFYREFGKKARVWDPYKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITD--RSDYKANP----------- 380
V++PDHYIFT D +NRNVD+LR F EQGI YFYD+ D R +K +P
Sbjct: 61 VMMPDHYIFTADSLSNRNVDVLRAFAEEQGIVYFYDVIDDPRGTWKFDPAKGYFRRQYGT 120
Query: 381 DYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
Y GVCH AL ++GH RPGEVLFGTDSHTC AGAF +FATGIGN+DAGFVMGTG
Sbjct: 121 KYAGVCHTALPEKGHVRPGEVLFGTDSHTCTAGAFNEFATGIGNTDAGFVMGTG 174
[25][TOP]
>UniRef100_B4D0Q5 Aconitate hydratase domain protein n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0Q5_9BACT
Length = 456
Score = 239 bits (609), Expect = 1e-61
Identities = 113/174 (64%), Positives = 135/174 (77%), Gaps = 13/174 (7%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEK+LA+A+ + V+ G+N+WVN DVLMTHDVCGPGTIGVFKREFG+ AKVWD +K+
Sbjct: 1 MTLTEKVLARASGKAHVQAGENVWVNVDVLMTHDVCGPGTIGVFKREFGKAAKVWDPKKL 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITD--RSDYKANPD---------- 383
VIIPDHYIFT D +NRNVDILR+F EQG+ YFYD+ D +K + +
Sbjct: 61 VIIPDHYIFTADSMSNRNVDILREFAREQGLPYFYDVIDDPNGHWKFDTEQGQLKKQYGK 120
Query: 384 -YKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
Y GVCH L +GHTRPGEVLFGTDSHTC AGAF +FATGIGN+DAGF++GTG
Sbjct: 121 SYTGVCHTTLPWKGHTRPGEVLFGTDSHTCMAGAFNEFATGIGNTDAGFILGTG 174
[26][TOP]
>UniRef100_B3QSN7 Homoaconitate hydratase family protein n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QSN7_CHLT3
Length = 431
Score = 224 bits (572), Expect = 2e-57
Identities = 98/160 (61%), Positives = 129/160 (80%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KILAK+A R +V PG+++W+N DVLMTHDVCGP TIG+++REFGE AKVWD +++V
Sbjct: 4 TITQKILAKSARRNTVDPGESVWLNVDVLMTHDVCGPPTIGIWEREFGEQAKVWDKDRLV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
I+PDHYIFTE+ ANRN+DILR F + + +YD+ +P YKGVCH+ALA+EG
Sbjct: 64 ILPDHYIFTENTHANRNIDILRKFAKDYDLPNYYDV-------GSPRYKGVCHIALAEEG 116
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ PG VLFGTDSHTC +GAFG F+TG+GN+DA F++GTG
Sbjct: 117 YNVPGTVLFGTDSHTCTSGAFGMFSTGVGNTDAAFILGTG 156
[27][TOP]
>UniRef100_C4C1N1 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4C1N1_9FUSO
Length = 435
Score = 224 bits (572), Expect = 2e-57
Identities = 103/162 (63%), Positives = 129/162 (79%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILAK + + V+PG+NIWVN DVLMTHDV GPG++ +FK+ FGE+AKVW+ EK+
Sbjct: 3 MTIVEKILAKKSGKDEVKPGENIWVNVDVLMTHDVTGPGSMAIFKKNFGENAKVWNNEKI 62
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFY-DITDRSDYKANPDYKGVCHVALAQ 416
V++PDHYIFT++ A RN++ + F EQ +KYFY T++ YKGVCH ALAQ
Sbjct: 63 VLVPDHYIFTKNEHAMRNIEYVNQFAVEQELKYFYPPFTNK--------YKGVCHTALAQ 114
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
EGHTRPGEVLFGTDSHTC AGAFG+FATGIGN+DA F++GTG
Sbjct: 115 EGHTRPGEVLFGTDSHTCTAGAFGEFATGIGNTDAAFILGTG 156
[28][TOP]
>UniRef100_C1ZRL8 Homoaconitate hydratase family protein/3-isopropylmalate
dehydratase, large subunit n=1 Tax=Rhodothermus marinus
DSM 4252 RepID=C1ZRL8_RHOMR
Length = 432
Score = 224 bits (572), Expect = 2e-57
Identities = 103/161 (63%), Positives = 125/161 (77%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+ A R V PG+NIW++ D+LMTHDVCGP TI +FKREFG +A+VWD EKV
Sbjct: 3 MTITEKILARHAGRDRVTPGENIWISVDILMTHDVCGPPTIEIFKREFGPNARVWDREKV 62
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+PDHYIFT D A RN++ILR+F EQ + Y+YD+ YKGVCHVALA+E
Sbjct: 63 VILPDHYIFTADPHARRNIEILREFAREQDLPYYYDV-------GTSRYKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G RPG VL GTDSHTC +GAFG F+TG+GN+DA F+MGTG
Sbjct: 116 GFNRPGIVLIGTDSHTCTSGAFGLFSTGVGNTDAAFIMGTG 156
[29][TOP]
>UniRef100_Q3APC5 3-isopropylmalate dehydratase n=1 Tax=Chlorobium chlorochromatii
CaD3 RepID=Q3APC5_CHLCH
Length = 431
Score = 220 bits (560), Expect = 6e-56
Identities = 100/161 (62%), Positives = 127/161 (78%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KI AK+A+R V PG+++W+N DVL+THDVCGP TI +FK +FG +AKVWD EKV+
Sbjct: 4 TITQKIFAKSAKRPFVDPGESVWLNVDVLLTHDVCGPPTIDIFKEKFGSNAKVWDPEKVI 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
I+PDHYIFT + A+RN+D+LR F EQG+ ++YD+ TDR YKGVCHVALA+E
Sbjct: 64 ILPDHYIFTANEHAHRNIDLLRQFAKEQGLPHYYDVGTDR--------YKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F TGIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGTGIGNTDAAFILGTG 156
[30][TOP]
>UniRef100_B3EKV4 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EKV4_CHLPB
Length = 432
Score = 219 bits (558), Expect = 1e-55
Identities = 98/160 (61%), Positives = 125/160 (78%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KILA+AA R V G+NIW+N DVL+THDVCGP T +F+ +FG +AKVWD EK+V
Sbjct: 4 TITQKILARAANRKFVEAGENIWLNVDVLLTHDVCGPPTFDIFREKFGPEAKVWDPEKIV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++PDHYIFTE+ A+RN+D+LR+F NEQ + +YD+ + YKGVCHVALAQEG
Sbjct: 64 VLPDHYIFTENEHAHRNIDLLREFANEQKLPNYYDVGTKR-------YKGVCHVALAQEG 116
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ PG VLFGTDSHTC +GAFG F TGIGN+DA F++GTG
Sbjct: 117 YNLPGTVLFGTDSHTCTSGAFGMFGTGIGNTDAAFILGTG 156
[31][TOP]
>UniRef100_B4S6N0 Homoaconitate hydratase family protein n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S6N0_PROA2
Length = 432
Score = 219 bits (557), Expect = 1e-55
Identities = 101/161 (62%), Positives = 124/161 (77%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KILA+AA R V G+N+W+N D+L+THDVCGP T +FK +FG DAKVWD EKVV
Sbjct: 4 TITQKILARAANRKFVNAGENVWLNVDILLTHDVCGPPTFDIFKEKFGPDAKVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFTE+ A+RN+D+LR F EQ + +YD+ TDR YKGVCHVALAQE
Sbjct: 64 VLPDHYIFTENEHAHRNIDLLRTFAAEQNLPNYYDVGTDR--------YKGVCHVALAQE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F TGIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGTGIGNTDAAFILGTG 156
[32][TOP]
>UniRef100_A6DRT0 3-isopropylmalate dehydratase n=1 Tax=Lentisphaera araneosa
HTCC2155 RepID=A6DRT0_9BACT
Length = 433
Score = 218 bits (556), Expect = 2e-55
Identities = 104/161 (64%), Positives = 121/161 (75%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKI+A AA R SV+ G+N+WV+ +VLMTHDVCGPGTIG+FK +FG DAKV+D E V
Sbjct: 3 MTLTEKIIANAAGRDSVKAGENVWVDVNVLMTHDVCGPGTIGIFKDKFGADAKVFDKENV 62
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VIIPDHYIFTED RA RN+DIL DF EQ I +Y +Y GVCHV L ++
Sbjct: 63 VIIPDHYIFTEDKRALRNIDILTDFAKEQDIPNYYQ-------PGTDNYMGVCHVTLPEK 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH RPGE++ GTDSHTC GA G FATGIGN+DA F MGTG
Sbjct: 116 GHVRPGEIILGTDSHTCTHGALGAFATGIGNTDAAFTMGTG 156
[33][TOP]
>UniRef100_B3EHN8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium limicola
DSM 245 RepID=B3EHN8_CHLL2
Length = 431
Score = 215 bits (547), Expect = 2e-54
Identities = 98/161 (60%), Positives = 125/161 (77%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KIL++AA R V G+N+W+N D+L+THDVCGP T +FK+EFG DAKVWD EKVV
Sbjct: 4 TITQKILSRAANRKFVDAGENVWLNVDILLTHDVCGPPTFDIFKQEFGPDAKVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F +EQ + +YD+ TDR YKGVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRQFASEQSLPNYYDVGTDR--------YKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNIPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[34][TOP]
>UniRef100_B4SDL0 Homoaconitate hydratase family protein n=1 Tax=Pelodictyon
phaeoclathratiforme BU-1 RepID=B4SDL0_PELPB
Length = 431
Score = 214 bits (544), Expect = 4e-54
Identities = 97/161 (60%), Positives = 125/161 (77%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KIL+KAA R V G+++W+N D+L+THDVCGP T +FK+EFG DAKVWD KVV
Sbjct: 4 TITQKILSKAANRKFVDAGESVWLNVDILLTHDVCGPPTFDIFKQEFGADAKVWDPRKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F EQ ++++YD+ TDR YKGVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRQFAKEQQLEHYYDVGTDR--------YKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[35][TOP]
>UniRef100_B3QM97 Homoaconitate hydratase family protein n=1 Tax=Chlorobaculum parvum
NCIB 8327 RepID=B3QM97_CHLP8
Length = 431
Score = 213 bits (543), Expect = 5e-54
Identities = 99/161 (61%), Positives = 123/161 (76%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KI AKAA R V PG ++W+N DVL+THDVCGP T +FK+EFG DAKVWD EKVV
Sbjct: 4 TITQKIFAKAANRKFVDPGQSVWLNVDVLLTHDVCGPPTFDIFKQEFGPDAKVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F EQ + +YD+ TDR Y+GVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRKFAAEQHLPNYYDVGTDR--------YRGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[36][TOP]
>UniRef100_A1BES2 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BES2_CHLPD
Length = 431
Score = 213 bits (541), Expect = 9e-54
Identities = 95/160 (59%), Positives = 122/160 (76%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KIL++AA R V G+N+W+N D+L+THDVCGP T +FK+EFG DAKVWD EKVV
Sbjct: 4 TITQKILSRAANRKFVDAGENVWLNVDILLTHDVCGPPTFDIFKQEFGPDAKVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++PDHYIFT + A+RN+D+LR F EQ + +YD+ + YKGVCHVALA+EG
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRQFAREQSLPNYYDVGTKR-------YKGVCHVALAEEG 116
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 117 FNIPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[37][TOP]
>UniRef100_A4SFC8 Homoaconitate hydratase family protein n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SFC8_PROVI
Length = 431
Score = 212 bits (540), Expect = 1e-53
Identities = 97/161 (60%), Positives = 123/161 (76%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KILA+AA R V G+N+W+N DVL+THDVCGP T +F +EFGE A+VWD EKVV
Sbjct: 4 TITQKILARAANRKFVNAGENVWLNVDVLLTHDVCGPPTFDIFNQEFGEGARVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F EQ + +YD+ TDR Y+GVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRKFAKEQNLPNYYDVGTDR--------YRGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[38][TOP]
>UniRef100_Q8KER8 3-isopropylmalate dehydratase, large subunit, putative n=1
Tax=Chlorobaculum tepidum RepID=Q8KER8_CHLTE
Length = 431
Score = 212 bits (539), Expect = 2e-53
Identities = 97/161 (60%), Positives = 123/161 (76%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KI A+AA R V PG ++W+N DVL+THDVCGP T +FK+EFG +AKVWD KVV
Sbjct: 4 TITQKIFARAANRKFVDPGQSVWLNVDVLLTHDVCGPPTFDIFKQEFGPNAKVWDPSKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F EQG+ +YD+ TDR Y+GVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRQFAAEQGLPNYYDVGTDR--------YRGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[39][TOP]
>UniRef100_Q0YQD5 Homoaconitate hydratase family protein:3-isopropylmalate
dehydratase, prokaryotic n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YQD5_9CHLB
Length = 431
Score = 211 bits (538), Expect = 2e-53
Identities = 96/161 (59%), Positives = 125/161 (77%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KIL++AA R V G+++W+N D+L+THDVCGP T +FK+EFG DAKVWD +KVV
Sbjct: 4 TITQKILSRAANRKFVDAGESVWLNVDILLTHDVCGPPTFDIFKQEFGPDAKVWDPQKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A+RN+D+LR F EQ + ++YD+ +DR YKGVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHAHRNIDLLRQFAAEQHLPHYYDVGSDR--------YKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F TGIGN+DA F++GTG
Sbjct: 116 GFNIPGTVLFGTDSHTCTSGAFGMFGTGIGNTDAAFILGTG 156
[40][TOP]
>UniRef100_Q6B920 3-isopropylmalate dehydratase large subunit n=1 Tax=Gracilaria
tenuistipitata var. liui RepID=Q6B920_GRATL
Length = 439
Score = 211 bits (538), Expect = 2e-53
Identities = 95/161 (59%), Positives = 123/161 (76%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT++EKILAKA+++ +V+ G+ IW +VLMTHD C PG I +FK+EFG+ AK+WD +
Sbjct: 7 MTMSEKILAKASQKNNVQAGEVIWSKVNVLMTHDPCSPGVISIFKKEFGDQAKIWDPKGH 66
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++IPDH+IFT D +AN N+ ++RDF EQG KYFYD + DYKGVCH+ALAQE
Sbjct: 67 IMIPDHFIFTSDEKANANIRMMRDFAQEQGHKYFYD-------PHSKDYKGVCHIALAQE 119
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH RPGEVL GTDSHT +GAFG FA G+GN+DA F++GTG
Sbjct: 120 GHNRPGEVLVGTDSHTVTSGAFGTFAIGVGNTDAAFILGTG 160
[41][TOP]
>UniRef100_Q3B597 3-isopropylmalate dehydratase n=1 Tax=Chlorobium luteolum DSM 273
RepID=Q3B597_PELLD
Length = 431
Score = 207 bits (526), Expect = 5e-52
Identities = 95/161 (59%), Positives = 122/161 (75%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+T+KIL++AA R V G+N+W+N D+L+THDVCGP T +F +EFG AKVWD EKVV
Sbjct: 4 TITQKILSRAANRKFVDAGENVWLNVDILLTHDVCGPPTFDIFNQEFGLGAKVWDPEKVV 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDI-TDRSDYKANPDYKGVCHVALAQE 419
++PDHYIFT + A RN+D+LR F EQ + ++YD+ T+R YKGVCHVALA+E
Sbjct: 64 VLPDHYIFTANEHARRNIDLLRKFAAEQHLPHYYDVGTER--------YKGVCHVALAEE 115
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG VLFGTDSHTC +GAFG F +GIGN+DA F++GTG
Sbjct: 116 GFNIPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTG 156
[42][TOP]
>UniRef100_B2VKF3 3-isopropylmalate dehydratase large subunit n=1 Tax=Erwinia
tasmaniensis RepID=B2VKF3_ERWT9
Length = 436
Score = 199 bits (505), Expect = 1e-49
Identities = 87/160 (54%), Positives = 118/160 (73%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+++KILA+A+ R V PG+ +W D+LM+HD C PG VFK+EFG AKVWD E+ +
Sbjct: 4 TISQKILARASGRKCVTPGEIVWAKVDILMSHDPCTPGVASVFKKEFGARAKVWDAERFI 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+IPDH++++ D +AN+N+ ++R+F EQ IKYFYD+ PDYKGVCH+ LA+ G
Sbjct: 64 MIPDHFVYSADPQANQNIRVMREFAREQQIKYFYDV-------GTPDYKGVCHIGLAEGG 116
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
HTRPGEVL GTDSHT AGAFG FA G+G +DA + +G+G
Sbjct: 117 HTRPGEVLLGTDSHTVTAGAFGCFAIGLGITDAAYALGSG 156
[43][TOP]
>UniRef100_C7P7J9 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
fervens AG86 RepID=C7P7J9_METFA
Length = 424
Score = 158 bits (400), Expect = 2e-37
Identities = 80/161 (49%), Positives = 103/161 (63%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILAKA+ + V PGD + N DV M HD+ GP T+ K E+G + KVWD EK+
Sbjct: 3 MTIVEKILAKASGKKEVSPGDIVMANIDVAMVHDITGPLTVNTLK-EYGIE-KVWDPEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH + + ++A N ++R FV EQGIKYFYDI + GVCH L ++
Sbjct: 61 VVLFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 GHVAPGEVVVGADSHTCTHGAFGAFATGIGSTDMAHVFATG 150
[44][TOP]
>UniRef100_P81291 Isopropylmalate/citramalate isomerase large subunit n=1
Tax=Methanocaldococcus jannaschii RepID=LEUC_METJA
Length = 424
Score = 157 bits (396), Expect = 6e-37
Identities = 80/161 (49%), Positives = 103/161 (63%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILAKA+ + V PGD + N DV M HD+ GP T+ K E+G + KVW+ EK+
Sbjct: 3 MTIVEKILAKASGKKEVSPGDIVMANIDVAMVHDITGPLTVNTLK-EYGIE-KVWNPEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH + + ++A N ++R FV EQGIKYFYDI + GVCH L ++
Sbjct: 61 VILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 GHVAPGEVVVGADSHTCTHGAFGAFATGIGSTDMAHVFATG 150
[45][TOP]
>UniRef100_C9RGT8 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
vulcanius M7 RepID=C9RGT8_9EURY
Length = 422
Score = 156 bits (394), Expect = 1e-36
Identities = 79/161 (49%), Positives = 102/161 (63%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILAKA+ + V PGD + DV M HD+ GP T+ K E+G + KVWD EK+
Sbjct: 1 MTIAEKILAKASGKKEVSPGDIVMAKIDVAMVHDITGPLTVNTLK-EYGIE-KVWDPEKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH + + ++A N ++R FV EQGIKYFYDI + GVCH L ++
Sbjct: 59 VILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIRE-----------GVCHQVLPEK 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGE++ G DSHTC GAFG FATGIG++D V TG
Sbjct: 108 GHVAPGEIVVGADSHTCTHGAFGAFATGIGSTDMAHVFATG 148
[46][TOP]
>UniRef100_O27439 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanothermobacter thermautotrophicus str. Delta H
RepID=LEUC1_METTH
Length = 419
Score = 149 bits (377), Expect = 1e-34
Identities = 77/161 (47%), Positives = 104/161 (64%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT++EKILA+A+ + V G+ + + DV MTHD+ GP ++ F R GED +VWD EK+
Sbjct: 3 MTVSEKILARASGKDRVEAGEIVMADIDVAMTHDLTGPLSVESF-RAIGED-RVWDPEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V+I DH + + + A +N I+RDFV EQGI+ FYD+ + GVCH L ++
Sbjct: 61 VVIFDHQVPADSIEAAQNHMIMRDFVEEQGIRNFYDVRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ GTDSHTC GA G FATGIG++D V TG
Sbjct: 110 GHVVPGEVVVGTDSHTCTHGALGAFATGIGSTDMAMVFATG 150
[47][TOP]
>UniRef100_C5U763 Homoaconitate hydratase family protein n=1 Tax=Methanocaldococcus
infernus ME RepID=C5U763_9EURY
Length = 424
Score = 149 bits (375), Expect = 2e-34
Identities = 76/161 (47%), Positives = 98/161 (60%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA+A+ + V PGD + D M HD+ GP T+ K+ E KVWD EK+
Sbjct: 3 MTIVEKILARASGKKEVSPGDIVMAKIDRAMVHDITGPLTVNTLKKYNIE--KVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH + + ++A N ++R+FV EQ IKYFYDI + GVCH L ++
Sbjct: 61 VILFDHQVPADSIKAAENHILMRNFVKEQNIKYFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEVL G DSHTC GA G FATGIG++D V TG
Sbjct: 110 GHVAPGEVLVGADSHTCTHGALGAFATGIGSTDMAHVFATG 150
[48][TOP]
>UniRef100_A6UPF6 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
vannielii SB RepID=A6UPF6_METVS
Length = 424
Score = 148 bits (374), Expect = 2e-34
Identities = 77/161 (47%), Positives = 97/161 (60%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKILAKA+ V PGD + + M HD+ GP ++ K+E E KVWD EK+
Sbjct: 3 MTLAEKILAKASGNSQVSPGDIVMAKVETAMVHDITGPLSVNTLKKEGIE--KVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH I + + A N ++R+FV EQGIK+FYDI + GVCH L ++
Sbjct: 61 VIPFDHQIPADSINAAENHILMRNFVKEQGIKHFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 GHVVPGTVIVGADSHTCTYGAFGSFATGIGSTDMAAVFATG 150
[49][TOP]
>UniRef100_A6VG92 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C7 RepID=A6VG92_METM7
Length = 424
Score = 144 bits (362), Expect = 5e-33
Identities = 75/161 (46%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKILAKA+ V PGD + + M HD+ GP ++ K+E +KVWD EK+
Sbjct: 3 MTLAEKILAKASGNTQVSPGDIVMAKVETAMVHDITGPLSVNTLKKE--GISKVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH I + + A N ++R+FV EQ IK+FYDI + GVCH L ++
Sbjct: 61 VIPFDHQIPADSINAAENHILMRNFVKEQNIKHFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 GHVVPGTVVVGADSHTCTYGAFGAFATGIGSTDMAAVFATG 150
[50][TOP]
>UniRef100_Q6LY44 3-isopropylmalate dehydratase n=1 Tax=Methanococcus maripaludis
RepID=Q6LY44_METMP
Length = 424
Score = 142 bits (359), Expect = 1e-32
Identities = 74/161 (45%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKILAKA+ V PGD + + M HD+ GP ++ K+E +KVWD EK+
Sbjct: 3 MTLAEKILAKASGNSEVSPGDIVMAKVETAMVHDITGPLSVNTLKKE--GISKVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH I + + A N ++R+FV EQ IK+FYDI + GVCH L ++
Sbjct: 61 VIPFDHQIPADSINAAENHILMRNFVKEQNIKHFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ G DSHTC GAFG FATGIG++D TG
Sbjct: 110 GHIVPGTVVVGADSHTCTYGAFGAFATGIGSTDMAAAFATG 150
[51][TOP]
>UniRef100_A9AAG0 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C6 RepID=A9AAG0_METM6
Length = 424
Score = 142 bits (358), Expect = 2e-32
Identities = 74/161 (45%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKILAKA+ V PGD + + M HD+ GP ++ K+E +KVWD EK+
Sbjct: 3 MTLAEKILAKASGNTQVSPGDIVMAKVETAMVHDITGPLSVNTLKKE--GISKVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH I + + N ++R+FV EQ IK+FYDI + GVCH L ++
Sbjct: 61 VIPFDHQIPADSINTAENHILMRNFVKEQNIKHFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 GHVVPGTVVVGADSHTCTYGAFGAFATGIGSTDMAAVFATG 150
[52][TOP]
>UniRef100_A4FX22 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanococcus
maripaludis C5 RepID=A4FX22_METM5
Length = 424
Score = 142 bits (357), Expect = 2e-32
Identities = 74/161 (45%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKILAKA+ V PGD + + M HD+ GP ++ K+E +KVWD EK+
Sbjct: 3 MTLAEKILAKASGNTQVSPGDIVMAKVETAMVHDITGPLSVNTLKKE--GISKVWDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH I + + A N ++R+FV EQ IK+FYDI + GVCH L ++
Sbjct: 61 VIPFDHQIPADSINAAENHILMRNFVKEQNIKHFYDIRE-----------GVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ G DSHTC GAFG FATGIG++D TG
Sbjct: 110 GHIVPGTVVVGADSHTCTYGAFGAFATGIGSTDMAAAFATG 150
[53][TOP]
>UniRef100_A6UTQ6 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
aeolicus Nankai-3 RepID=A6UTQ6_META3
Length = 425
Score = 141 bits (356), Expect = 3e-32
Identities = 78/162 (48%), Positives = 94/162 (58%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTE-K 236
MTL EKILAKA+ +V PGD + + M HD+ GP T+ K E E KVWD E K
Sbjct: 3 MTLAEKILAKASGNKTVAPGDIVMAKIETAMAHDITGPLTVNTLKNEGIE--KVWDNEEK 60
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ I+ DH I + + A N +LR FV EQGIK FYDI + GVCH L +
Sbjct: 61 ITILFDHQIPADSITAAENHALLRKFVKEQGIKNFYDIRE-----------GVCHQVLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+GH PG V G DSHTC GAFG FATGIG++D V TG
Sbjct: 110 KGHVLPGTVAVGADSHTCTYGAFGTFATGIGSTDMAAVFATG 151
[54][TOP]
>UniRef100_Q8TVF2 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Methanopyrus
kandleri RepID=LEUC1_METKA
Length = 418
Score = 134 bits (338), Expect = 3e-30
Identities = 70/160 (43%), Positives = 98/160 (61%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKIL++A+ + GD + N DV M HD+ GP T+ + E G + +VWD K+V
Sbjct: 4 TMAEKILSRASGEDA-EAGDIVVANIDVAMVHDITGPITVQRLE-EMGVE-RVWDPSKIV 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH + + V A N I+R+FV EQGI++FYD+ + GVCH L ++G
Sbjct: 61 VLFDHQVPADSVEAAENHKIMREFVEEQGIEHFYDVRE-----------GVCHQVLPEKG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H RPG+V+ G DSHTC GA G FATGIG++D V TG
Sbjct: 110 HVRPGDVIVGADSHTCTHGALGAFATGIGSTDMAAVFATG 149
[55][TOP]
>UniRef100_Q2NE97 LeuC1 n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE97_METST
Length = 418
Score = 134 bits (337), Expect = 4e-30
Identities = 69/161 (42%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT++EKILAK++ V G+ + + D M HD+ GP T+ ++ KVWD +K+
Sbjct: 3 MTISEKILAKSSGNEKVEAGEIVMADIDTAMVHDLTGPLTLQALEKI--NTNKVWDPDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH + + + A +N ILR FV EQGIK FYD+ Y+GVCH L ++
Sbjct: 61 VIPFDHQVPADTLDAAKNHQILRKFVKEQGIKNFYDV-----------YEGVCHQVLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG ++ G+DSHTC GA G F TGIG++D V TG
Sbjct: 110 GHVLPGTIVVGSDSHTCTHGALGAFGTGIGSTDMAMVFATG 150
[56][TOP]
>UniRef100_B4WHZ3 3-isopropylmalate dehydratase, large subunit subfamily n=1
Tax=Synechococcus sp. PCC 7335 RepID=B4WHZ3_9SYNE
Length = 567
Score = 132 bits (332), Expect = 2e-29
Identities = 64/169 (37%), Positives = 98/169 (57%), Gaps = 4/169 (2%)
Frame = +3
Query: 48 IATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWD 227
+A PMT+ EK+LA+A+ VRPG+ ++ D+ M+HD +F+++FG +A VWD
Sbjct: 139 LARPMTVAEKLLAQASGNSYVRPGEVVFAKVDLAMSHDAIAGPVGALFQQQFGPNATVWD 198
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILR----DFVNEQGIKYFYDITDRSDYKANPDYKGV 395
K+V++ DH+I D+R +R L DF +QG F D + + G+
Sbjct: 199 PGKIVLVADHFIQVNDIRQDRGAISLHQQMVDFAKQQGCHLF-------DVVSPGEAAGI 251
Query: 396 CHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
CHV L ++G RPG ++ GTDSH+C GAFG F+TG+G +D + G
Sbjct: 252 CHVLLPEQGFVRPGMMIAGTDSHSCTYGAFGSFSTGVGTTDMANIFAMG 300
[57][TOP]
>UniRef100_UPI0001966774 hypothetical protein METSMIF1_00490 n=1 Tax=Methanobrevibacter
smithii DSM 2374 RepID=UPI0001966774
Length = 415
Score = 131 bits (330), Expect = 3e-29
Identities = 71/162 (43%), Positives = 93/162 (57%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P T++EKILAKAA + V GD + N DV MTHD+ GP ++ F++ KVWD K
Sbjct: 2 PKTMSEKILAKAAGKDEVEAGDIVIANIDVAMTHDLTGPLSVQSFEKIGA--TKVWDPSK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+VI DH + + + + N I+R FV EQ I+ FYD+ GVCH L +
Sbjct: 60 IVIPFDHQVPADSIDSANNHIIMRKFVKEQKIENFYDVN-----------AGVCHQILPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ G DSHTC GA G F+TGIG++D V G
Sbjct: 109 LGHVVPGEVIVGADSHTCTHGALGAFSTGIGSTDMAMVFAEG 150
[58][TOP]
>UniRef100_A5UMS7 3-isopropylmalate dehydratase, large subunit, LeuC n=1
Tax=Methanobrevibacter smithii ATCC 35061
RepID=A5UMS7_METS3
Length = 415
Score = 131 bits (330), Expect = 3e-29
Identities = 71/162 (43%), Positives = 93/162 (57%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P T++EKILAKAA + V GD + N DV MTHD+ GP ++ F++ KVWD K
Sbjct: 2 PKTMSEKILAKAAGKDEVEAGDIVIANIDVAMTHDLTGPLSVQSFEKIGA--TKVWDPSK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+VI DH + + + + N I+R FV EQ I+ FYD+ GVCH L +
Sbjct: 60 IVIPFDHQVPADSIDSANNHIIMRKFVKEQKIENFYDVN-----------AGVCHQILPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ G DSHTC GA G F+TGIG++D V G
Sbjct: 109 LGHVVPGEVIVGADSHTCTHGALGAFSTGIGSTDMAMVFAEG 150
[59][TOP]
>UniRef100_B9AFU3 Putative uncharacterized protein n=1 Tax=Methanobrevibacter smithii
DSM 2375 RepID=B9AFU3_METSM
Length = 414
Score = 130 bits (327), Expect = 6e-29
Identities = 70/162 (43%), Positives = 93/162 (57%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P T++EKILA+AA + V GD + N DV MTHD+ GP ++ F++ KVWD K
Sbjct: 2 PKTMSEKILARAAGKDEVEAGDIVIANIDVAMTHDLTGPLSVQSFEKIGA--TKVWDPSK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+VI DH + + + + N I+R FV EQ I+ FYD+ GVCH L +
Sbjct: 60 IVIPFDHQVPADSIDSANNHIIMRKFVKEQKIENFYDVN-----------AGVCHQILPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PGEV+ G DSHTC GA G F+TGIG++D V G
Sbjct: 109 LGHVVPGEVIVGADSHTCTHGALGAFSTGIGSTDMAMVFAEG 150
[60][TOP]
>UniRef100_A0ZF76 3-isopropylmalate dehydratase, LeuC subunit n=1 Tax=Nodularia
spumigena CCY9414 RepID=A0ZF76_NODSP
Length = 574
Score = 128 bits (322), Expect = 2e-28
Identities = 61/176 (34%), Positives = 99/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 27 STAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFG 206
+T V PMTL EK++AKA+ VRPG+ ++ D+ ++HD F + +G
Sbjct: 139 TTPKSVTPQRPMTLVEKLIAKASGNTYVRPGEVVFAQVDLALSHDAVAGPVATTFYKHYG 198
Query: 207 EDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILR----DFVNEQGIKYFYDITDRSDYKA 374
++AK+WD ++VV++ DH+I D+R ++ +++ DF +QG F D +
Sbjct: 199 KEAKLWDAQRVVLVADHFIQVNDIRNDQKANVMYQEMIDFAKKQGCHLF-------DIVS 251
Query: 375 NPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ G+CHV L ++G RPG ++ GTDSHTC GA G F+ G+G +D + G
Sbjct: 252 PGEAAGICHVLLPEKGFVRPGMIIAGTDSHTCTYGALGAFSAGVGTTDMANIYAMG 307
[61][TOP]
>UniRef100_B9L0Y1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermomicrobium roseum DSM 5159 RepID=B9L0Y1_THERP
Length = 422
Score = 127 bits (319), Expect = 5e-28
Identities = 70/161 (43%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA+AA R V PG+ I V D++MT+D+ P +I FK+ E +V+D +KV
Sbjct: 6 MTMAEKILARAAGRRRVEPGEIIEVAVDLVMTNDITAPLSIAEFKKLGVE--RVFDPKKV 63
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH++ +D++A I+R+F EQG YF G+ HV L +
Sbjct: 64 VFVPDHFVPAKDIKAAEQSKIMREFALEQGAIYF-----------EIGRAGIEHVVLPEH 112
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G TRPG V+ G DSHTC GAF FATG+G++D M TG
Sbjct: 113 GLTRPGMVIIGADSHTCTYGAFNAFATGMGSTDIAAAMATG 153
[62][TOP]
>UniRef100_Q46AJ7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosarcina
barkeri str. Fusaro RepID=Q46AJ7_METBF
Length = 431
Score = 127 bits (319), Expect = 5e-28
Identities = 69/164 (42%), Positives = 97/164 (59%), Gaps = 2/164 (1%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKR--EFGEDAKVWDT 230
PMT++EKI +KA+ V+ GD + N D+ MTHD+ GP + F + E+ KVWD
Sbjct: 11 PMTVSEKIFSKASG-SPVKAGDFVLANIDLAMTHDITGPLAVKGFYEIMKDKEEKKVWDP 69
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
K+VI+ DH + + + A N +LR F EQGI YD+ Y+GVCH L
Sbjct: 70 TKIVIVFDHQVPADSINATANHIMLRKFAEEQGILN-YDV-----------YEGVCHQVL 117
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
++GH PG+++ G+DSHTC GA G F+TGIG++D V TG
Sbjct: 118 PEKGHVLPGDLIVGSDSHTCAYGALGAFSTGIGSTDMAAVFATG 161
[63][TOP]
>UniRef100_Q8PUG1 3-isopropylmalate dehydratase large subunit 2 n=1
Tax=Methanosarcina mazei RepID=LEUC2_METMA
Length = 420
Score = 127 bits (318), Expect = 7e-28
Identities = 70/165 (42%), Positives = 99/165 (60%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGP----GTIGVFKREFGEDAKVWD 227
MT++EKI +KA+ V+ GD + N D+ MTHD+ GP G + + E ED KVWD
Sbjct: 1 MTVSEKIFSKASGT-PVKAGDFVLANIDLAMTHDITGPLAVQGFYEIMRDE--EDKKVWD 57
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
K+VII DH + + + A +N +LR F EQGI YD+ Y+GVCH
Sbjct: 58 PSKIVIIFDHQVPADSINAAQNHIMLRKFAKEQGILN-YDV-----------YEGVCHQV 105
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
L ++GH +PG+++ G+DSHTC G+ G F+TGIG++D V TG
Sbjct: 106 LPEKGHVKPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATG 150
[64][TOP]
>UniRef100_B8E2X0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
turgidum DSM 6724 RepID=B8E2X0_DICTD
Length = 424
Score = 126 bits (316), Expect = 1e-27
Identities = 64/161 (39%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA + + V PG+ I+V D L+ +D+ GP I F++ E KV+D EK+
Sbjct: 3 MTITEKILADHSSKKEVFPGELIFVKLDFLLANDITGPLAIKEFEKIGVE--KVFDNEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH +D+++ ILR+F +QGIKY+Y++ G+ H L +E
Sbjct: 61 ALVPDHSTPNKDIKSAMQSKILREFAKKQGIKYYYEV----------GRVGIEHALLPEE 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+ + G DSHTC GA G F+TG+G++D + M TG
Sbjct: 111 GLVLPGDAIIGADSHTCTYGALGAFSTGVGSTDLAYAMATG 151
[65][TOP]
>UniRef100_Q0W5L6 3-isopropylmalate dehydratase, large subunit n=1 Tax=uncultured
methanogenic archaeon RC-I RepID=Q0W5L6_UNCMA
Length = 421
Score = 126 bits (316), Expect = 1e-27
Identities = 68/165 (41%), Positives = 101/165 (61%), Gaps = 6/165 (3%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGP----GTIGVFKREFGEDAKVWD 227
MT+TEKI +A+ + SV+ GD + + D MTHD+ GP G + K + E+ KVWD
Sbjct: 1 MTITEKIFGRASGK-SVKAGDFVLADIDRAMTHDITGPLAVEGFYEIVKNQ--EEKKVWD 57
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
EK+VI+ DH + + + A +N +LR F +Q I++FYD+ ++GVCH
Sbjct: 58 PEKIVILFDHQVPADSLAAAQNHIMLRKFAKDQKIRHFYDV-----------FEGVCHQV 106
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
+ ++GH PG ++ G+DSHTC GA G FATGIG++D A F +G
Sbjct: 107 MPEKGHVEPGMLVVGSDSHTCAYGALGAFATGIGSTDMAAAFALG 151
[66][TOP]
>UniRef100_B2J8P2 Homoaconitate hydratase family protein n=1 Tax=Nostoc punctiforme
PCC 73102 RepID=B2J8P2_NOSP7
Length = 569
Score = 125 bits (314), Expect = 2e-27
Identities = 60/166 (36%), Positives = 94/166 (56%), Gaps = 4/166 (2%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMTL EK+L A+ V+PG+ ++ D+ ++HD F +++GE K+WD++K
Sbjct: 144 PMTLVEKLLGLASRNSYVQPGEVVFAQVDLALSHDAVAGPVAQTFYKQYGEGTKLWDSQK 203
Query: 237 VVIIPDHYIFTEDVRANRNVDILR----DFVNEQGIKYFYDITDRSDYKANPDYKGVCHV 404
VV++ DH+I D+RA+ ++ +F QG F D + + G+CHV
Sbjct: 204 VVLVADHFIQINDIRADDKAYLMYEQMIEFAKFQGCHLF-------DVVSPGEATGICHV 256
Query: 405 ALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
L ++G RPG ++ GTDSHTC GA G F+TG+G +D + TG
Sbjct: 257 LLPEKGFVRPGMIIAGTDSHTCTYGALGAFSTGVGTTDMANIYATG 302
[67][TOP]
>UniRef100_Q12UW0 Homoaconitase large subunit n=1 Tax=Methanococcoides burtonii DSM
6242 RepID=Q12UW0_METBU
Length = 428
Score = 125 bits (313), Expect = 3e-27
Identities = 66/164 (40%), Positives = 98/164 (59%), Gaps = 2/164 (1%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFK--REFGEDAKVWDT 230
PMT++EKI +KA+ + +V+ GD + N D MTHD+ GP + F E+ KVWD
Sbjct: 8 PMTISEKIFSKASGK-TVKAGDFVLANIDRAMTHDITGPLAVDGFYDIMRDKEEKKVWDP 66
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
K+VI+ DH + + + A+ N +LR F EQGI YD+ Y+GVCH +
Sbjct: 67 SKIVIVFDHQVPADSLNASANHIMLRKFAKEQGILN-YDV-----------YEGVCHQVM 114
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ GH RPG+++ G+DSHTC G+ G F+TG+G++D V +G
Sbjct: 115 PEMGHVRPGDLIVGSDSHTCAYGSLGAFSTGVGSTDMSAVFASG 158
[68][TOP]
>UniRef100_A4FW44 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanococcus
maripaludis C5 RepID=A4FW44_METM5
Length = 418
Score = 124 bits (311), Expect = 4e-27
Identities = 68/161 (42%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKI++K + +V GD++ ++ DV MTHD P T+ F++ KVWD EK+
Sbjct: 1 MTLAEKIISKNVGK-NVYAGDSVEIDVDVAMTHDGTTPLTVKAFEQI---SDKVWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH I +A I R+F+ +QGIK +Y D +G+CH L ++
Sbjct: 57 VIIFDHNIPANTSKAANMQVITREFIKKQGIKNYY-----------LDGEGICHQVLPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P ++ G DSHTC GAFG FATG G +D G+V TG
Sbjct: 106 GHVKPNMIIAGADSHTCTHGAFGAFATGFGATDMGYVYATG 146
[69][TOP]
>UniRef100_Q8TQZ3 3-isopropylmalate dehydratase large subunit 2 n=1
Tax=Methanosarcina acetivorans RepID=LEUC2_METAC
Length = 420
Score = 123 bits (309), Expect = 7e-27
Identities = 69/165 (41%), Positives = 97/165 (58%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGP----GTIGVFKREFGEDAKVWD 227
MT++EKI +KA+ V+ GD + N D+ MTHD+ GP G + + E E+ KVWD
Sbjct: 1 MTVSEKIFSKASGT-PVKAGDFVLANIDLAMTHDITGPLAVQGFYEIMRDE--EEKKVWD 57
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
K+VII DH + + + A N +LR F EQGI YD+ Y+GVCH
Sbjct: 58 PSKIVIIFDHQVPADSINAAENHIMLRKFAKEQGILN-YDV-----------YEGVCHQV 105
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
L ++GH PG+++ G+DSHTC G+ G F+TGIG++D V TG
Sbjct: 106 LPEKGHVLPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATG 150
[70][TOP]
>UniRef100_A9A9I4 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C6 RepID=A9A9I4_METM6
Length = 418
Score = 123 bits (308), Expect = 1e-26
Identities = 67/161 (41%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKI++K + +V GD++ ++ D+ MTHD P T+ F++ KVWD EK+
Sbjct: 1 MTLAEKIISKNVGK-NVYAGDSVEIDVDIAMTHDGTTPLTVKAFEQITD---KVWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH I +A I R+F+ +QGIK +Y D +G+CH L ++
Sbjct: 57 VIIFDHNIPANTSKAANMQLITREFIKKQGIKNYY-----------LDGEGICHQVLPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P ++ G DSHTC GAFG FATG G +D G+V TG
Sbjct: 106 GHVKPNMIIAGADSHTCTHGAFGAFATGFGATDMGYVYATG 146
[71][TOP]
>UniRef100_A6VH65 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
maripaludis C7 RepID=A6VH65_METM7
Length = 418
Score = 123 bits (308), Expect = 1e-26
Identities = 67/161 (41%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKI++K + +V GD++ ++ D+ MTHD P T+ F++ KVWD EK+
Sbjct: 1 MTLAEKIISKNVGK-NVYAGDSVEIDVDIAMTHDGTTPLTVKAFEQI---SDKVWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH I +A I R+F+ + GIK +Y D +G+CH L ++
Sbjct: 57 VIIFDHNIPANTSKAANMQVITREFIKKHGIKNYY-----------LDGEGICHQVLPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P ++ G DSHTC GAFG FATG G +D GFV TG
Sbjct: 106 GHVKPNMIIAGADSHTCTHGAFGAFATGFGATDMGFVYATG 146
[72][TOP]
>UniRef100_Q46RP3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ralstonia
eutropha JMP134 RepID=Q46RP3_RALEJ
Length = 435
Score = 122 bits (306), Expect = 2e-26
Identities = 63/171 (36%), Positives = 97/171 (56%)
Frame = +3
Query: 30 TAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGE 209
+A V ATP TL +K+LA+A+ R V PG+ + D+ M HD GP + + G
Sbjct: 5 SAQAVAAATPQTLAQKLLARASGRAHVTPGEIVTCRVDLAMMHDSGGPRRVKPLLEKIG- 63
Query: 210 DAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYK 389
A+VWD +VV++ DHY+ D + + V I R++V E+G+ F+D+ +
Sbjct: 64 -ARVWDPSRVVVVTDHYVPAHDADSRKIVQIAREWVREEGVARFHDM------------E 110
Query: 390 GVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G+CHV + Q+G+ RPG + G DSH+ GAFG + GIG ++ V+ TG
Sbjct: 111 GICHVVVPQKGYLRPGMMAVGGDSHSSTGGAFGTYMFGIGATEMLGVLVTG 161
[73][TOP]
>UniRef100_A0B7V1 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanosaeta
thermophila PT RepID=A0B7V1_METTP
Length = 423
Score = 122 bits (306), Expect = 2e-26
Identities = 62/160 (38%), Positives = 92/160 (57%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL+EKI ++AA + R G+ + + D M HD+ GP + F G+ A+VW+ ++V
Sbjct: 12 TLSEKIFSRAANK-EARAGEFVMASIDCAMIHDITGPLAVRGFYEIAGKGARVWNPSRIV 70
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
I+ DH + + ++A N +LR F EQGI YD+ + G+CH + + G
Sbjct: 71 ILFDHQVPADSIKAAENHQMLRAFAKEQGI-INYDV-----------FSGICHQVMPENG 118
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H PG+++ GTDSHTC GA G FATGIG++D V TG
Sbjct: 119 HVLPGQLIVGTDSHTCTYGALGAFATGIGSTDMASVFATG 158
[74][TOP]
>UniRef100_Q3AEQ4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Carboxydothermus hydrogenoformans Z-2901
RepID=Q3AEQ4_CARHZ
Length = 421
Score = 121 bits (304), Expect = 3e-26
Identities = 63/161 (39%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A + V PG+ I D ++ +D+ GP I FK+ G D+ V+D ++V
Sbjct: 3 MTMTEKILAYHAGKELVEPGELISCKVDAVLANDITGPVAISEFKK-IGVDS-VFDRDRV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ ILRDF EQ + Y++++ G+ HV L +E
Sbjct: 61 YLVPDHFTPNKDIKSAEQAKILRDFAKEQNLTYYFEVGKM----------GIEHVLLPEE 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGEV+ G DSHTC G G FATG+G++D M G
Sbjct: 111 GLVLPGEVIIGADSHTCTYGGLGAFATGVGSTDLAAAMALG 151
[75][TOP]
>UniRef100_B5YEF5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Dictyoglomus
thermophilum H-6-12 RepID=B5YEF5_DICT6
Length = 424
Score = 120 bits (302), Expect = 5e-26
Identities = 61/161 (37%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA + + V PG+ I+V D ++ +D+ GP I F++ E KV+D E++
Sbjct: 3 MTITEKILADHSGKKEVFPGELIFVKLDFILANDITGPLAIKEFEKIGVE--KVFDNERI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
+IPDH +D+++ +LR+F QGI+Y+Y++ G+ H L +E
Sbjct: 61 ALIPDHSTPNKDIKSAMQSKMLREFAKRQGIEYYYEV----------GRVGIEHALLPEE 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+ + G DSHTC GA G F+TG+G++D + M TG
Sbjct: 111 GLVLPGDAIIGADSHTCTYGALGAFSTGVGSTDLAYAMATG 151
[76][TOP]
>UniRef100_Q6LX72 Aconitase Family n=1 Tax=Methanococcus maripaludis
RepID=Q6LX72_METMP
Length = 418
Score = 120 bits (302), Expect = 5e-26
Identities = 66/161 (40%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKI++K + +V D++ ++ D+ MTHD P T+ F++ KVWD EK+
Sbjct: 1 MTLAEKIISKNVGK-NVYAKDSVEISVDIAMTHDGTTPLTVKAFEQI---SDKVWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH I +A I R+F+ +QGIK +Y D +G+CH L ++
Sbjct: 57 VIIFDHNIPANTSKAANMQVITREFIKKQGIKNYY-----------LDGEGICHQVLPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P ++ G DSHTC GAFG FATG G +D G+V TG
Sbjct: 106 GHVKPNMIIAGADSHTCTHGAFGAFATGFGATDMGYVYATG 146
[77][TOP]
>UniRef100_Q2NFC0 LeuC2 n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NFC0_METST
Length = 415
Score = 120 bits (302), Expect = 5e-26
Identities = 66/161 (40%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M ++EKILAKA+ + V PGD I N DV M+HD P TI VF++ KVWD EK+
Sbjct: 1 MNISEKILAKASNKEEVSPGDTITANIDVAMSHDGTSPPTIKVFEKIAD---KVWDPEKI 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH I + + ++R+F +Q I Y +GVCH L
Sbjct: 58 VLVFDHVIPANTIGSAEFQQVVREFGKKQKIPNMYI-----------QGEGVCHEVLPDY 106
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P V+ G DSHTC GAFG F+TG+G +D V TG
Sbjct: 107 GHVKPSTVIVGADSHTCTYGAFGAFSTGLGATDLAMVYATG 147
[78][TOP]
>UniRef100_O27668 3-isopropylmalate dehydratase large subunit 2 n=1
Tax=Methanothermobacter thermautotrophicus str. Delta H
RepID=LEUC2_METTH
Length = 428
Score = 120 bits (300), Expect = 8e-26
Identities = 66/163 (40%), Positives = 87/163 (53%), Gaps = 2/163 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFK--REFGEDAKVWDTE 233
M +TEKILA+AA V PG+ I D+ MTHD P TI F+ G A+VWD E
Sbjct: 4 MNMTEKILAEAAGLREVTPGEIIEARVDLAMTHDGTSPPTIRTFRDIASRGGPARVWDPE 63
Query: 234 KVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALA 413
++V++ DH + + A + R+F EQGI + + G+CH L
Sbjct: 64 RIVMVFDHNVPANTIGAAEFQRVTREFAREQGIVNIFQ-----------NAAGICHQVLP 112
Query: 414 QEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ G RPG V+ G DSHTC GAFG FATG+G +D V TG
Sbjct: 113 ERGFVRPGMVIVGADSHTCTYGAFGAFATGMGATDMAMVFATG 155
[79][TOP]
>UniRef100_O28316 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Archaeoglobus
fulgidus RepID=LEUC1_ARCFU
Length = 418
Score = 120 bits (300), Expect = 8e-26
Identities = 66/160 (41%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL EKI +KA+ + V+ G+ + N D+ M HD+ P I F+ G DAKVWD KV+
Sbjct: 4 TLVEKIFSKASGK-EVKAGEFVMANIDLAMIHDITAPLAIKAFREILGSDAKVWDKSKVI 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+ DH + + V A N +LR F EQGI N D KG + E
Sbjct: 63 MAFDHQVPADSVHAAENHKMLRKFAEEQGI-------------LNYDVKGGIAHQIMVEN 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H PG ++ G DSHTC GA G FATGIG++D GFV+ G
Sbjct: 110 HVEPGMLIVGADSHTCMYGALGAFATGIGSTDMGFVLAMG 149
[80][TOP]
>UniRef100_C1QEQ5 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
murdochii DSM 12563 RepID=C1QEQ5_9SPIR
Length = 227
Score = 119 bits (297), Expect = 2e-25
Identities = 64/161 (39%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G+ I V TD+++ +D+ P I F++ +G D KV+D EK+
Sbjct: 1 MTITQKILAAHAGVDKVEAGELIMVKTDLVLGNDITSPVAINEFEK-YGFD-KVFDKEKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D++A RDF N+ I +YD+ D GV H L ++
Sbjct: 59 ALVMDHFAPNKDIKAAEQCKQCRDFANKYDISNYYDVGDM----------GVEHALLPEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGEV+ G DSHTC GAFG F+TG+G++D M TG
Sbjct: 109 GLVSPGEVIIGADSHTCTYGAFGAFSTGVGSTDMAAAMATG 149
[81][TOP]
>UniRef100_C0R088 3-isopropylmalate dehydratase large subunit n=1 Tax=Brachyspira
hyodysenteriae WA1 RepID=C0R088_BRAHW
Length = 415
Score = 118 bits (296), Expect = 2e-25
Identities = 64/161 (39%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G+ I V TD+++ +D+ P I F++ +G D KV+D EK+
Sbjct: 1 MTITQKILAAHAGVEKVEAGELIMVKTDLVLGNDITSPVAINEFEK-YGFD-KVFDKEKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D++A RDF N+ I +YD+ D GV H L ++
Sbjct: 59 ALVMDHFAPNKDIKAAEQCKQCRDFANKYDISNYYDVGDM----------GVEHALLPEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGEV+ G DSHTC GAFG F+TG+G++D M TG
Sbjct: 109 GLVAPGEVIIGADSHTCTYGAFGAFSTGVGSTDMAAAMATG 149
[82][TOP]
>UniRef100_C8WM14 3-isopropylmalate dehydratase, large subunit n=2 Tax=Eggerthella
lenta DSM 2243 RepID=C8WM14_9ACTN
Length = 422
Score = 118 bits (296), Expect = 2e-25
Identities = 62/162 (38%), Positives = 95/162 (58%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMT+ EKILA A V PG I + D+++++DV P + F R+ G + KV++ K
Sbjct: 4 PMTMAEKILAAHAGLDEVEPGQLIECDLDLVLSNDVTAPIAVKEF-RKIGVE-KVFNPTK 61
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++PDHY+ +D+++ I+RDF EQGI ++Y++ GV H L +
Sbjct: 62 IALVPDHYVPNKDIKSAEQAKIVRDFAREQGITHYYEV----------GCMGVEHALLPE 111
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G G+++ G DSHTC GA G FATG+G++DAG TG
Sbjct: 112 QGVVGAGDLIIGADSHTCTYGALGAFATGVGSTDAGVGYATG 153
[83][TOP]
>UniRef100_C8SB74 Homoaconitate hydratase family protein n=1 Tax=Ferroglobus placidus
DSM 10642 RepID=C8SB74_FERPL
Length = 419
Score = 118 bits (296), Expect = 2e-25
Identities = 66/160 (41%), Positives = 88/160 (55%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL+EKI ++ + + V+ GD + DV M HD+ GP I F+ GE AKVWD +K+V
Sbjct: 4 TLSEKIFSEKSGK-DVKAGDFVLAEIDVAMIHDITGPLAIKAFREIAGEKAKVWDPKKIV 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
I DH + V A N +LR F EQGI YD+ + G+ H + ++G
Sbjct: 63 IAFDHQAPADSVAAAENHKMLRKFAKEQGI-LLYDVGE-----------GIAHQIMVEKG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H PG + G DSHTC GA G FATGIG++D G V G
Sbjct: 111 HVLPGMLAVGADSHTCMYGALGAFATGIGSTDMGAVFALG 150
[84][TOP]
>UniRef100_Q2LWJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Syntrophus
aciditrophicus SB RepID=LEUC_SYNAS
Length = 420
Score = 118 bits (296), Expect = 2e-25
Identities = 63/161 (39%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKIL + + VRPG I D+ + +DV P I F++ G+ KV+D +KV
Sbjct: 3 MTITEKILCRHTDLDEVRPGMLINAKVDIALGNDVTAPLAIDEFRKAGGK--KVFDRDKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V+IPDH+ +D+ + I+RDF EQ I ++Y++ + GV H L ++
Sbjct: 61 VLIPDHFTPNKDINSAAQCKIMRDFAREQEITHYYEVGE----------VGVEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GIVLPGDLVIGADSHTCTYGALGAFATGVGSTDLAAAMLTG 151
[85][TOP]
>UniRef100_O67078 3-isopropylmalate dehydratase large subunit n=1 Tax=Aquifex
aeolicus RepID=LEUC_AQUAE
Length = 432
Score = 118 bits (295), Expect = 3e-25
Identities = 59/161 (36%), Positives = 98/161 (60%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+ A + V PG+ I D+ M +DV P I + ++ +G D KV+D E++
Sbjct: 3 MTITEKILAEHAGKKEVHPGELITAKIDLAMANDVTAPLAIKILEK-YGID-KVFDPERI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ H++ +D+++ I+R+FV + GIK+F++ + +G+ H L ++
Sbjct: 61 ALVLSHFVPAKDIKSAEQAKIVREFVKKHGIKWFFE-----------EGEGIEHAILPEQ 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++D + M TG
Sbjct: 110 GLVVPGDLVVGADSHTCTYGALGAFATGVGSTDIAYAMATG 150
[86][TOP]
>UniRef100_A8AB09 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ignicoccus
hospitalis KIN4/I RepID=A8AB09_IGNH4
Length = 419
Score = 117 bits (294), Expect = 4e-25
Identities = 65/162 (40%), Positives = 91/162 (56%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P T+ EKIL +A+ + V PG+ + N D+ M HD+ GP + V + GE +VWD +K
Sbjct: 2 PKTMAEKILGRASGK-DVSPGEIVEANVDLAMVHDLTGPHVVEVVEEIAGE-VRVWDPDK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V II DH++ + +RA I+R + GIK F+D+ G+CH L +
Sbjct: 60 VAIIFDHHVPADKIRAAELQAIMRKVARKLGIKKFHDV----------GRGGICHQVLVE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
E + RPG ++ G DSHT +GA G FATGIG SD V TG
Sbjct: 110 ERYARPGMLIVGADSHTVTSGAVGAFATGIGASDMAMVWLTG 151
[87][TOP]
>UniRef100_C5UT24 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
botulinum E1 str. 'BoNT E Beluga' RepID=C5UT24_CLOBO
Length = 419
Score = 117 bits (293), Expect = 5e-25
Identities = 64/161 (39%), Positives = 97/161 (60%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ G I VN D+++ +D+ P I FK+ FG D KV++ ++
Sbjct: 3 MTMTQKILASHAGLESVKAGQLIEVNLDLVLGNDITTPVAINEFKK-FGLD-KVFNKSQI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A V +R+F N+ GIK F+++ + G+ H L ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQVKYVREFSNKMGIKNFFEVGEM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVPGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[88][TOP]
>UniRef100_C4CHB6 3-isopropylmalate dehydratase, large subunit n=1 Tax=Sphaerobacter
thermophilus DSM 20745 RepID=C4CHB6_9CHLR
Length = 418
Score = 117 bits (293), Expect = 5e-25
Identities = 66/160 (41%), Positives = 92/160 (57%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+TEKIL++AA R V PG+ V D++MT+D+ P I FK+ E KV+D KVV
Sbjct: 4 TMTEKILSRAAGR-RVEPGEIAEVAVDLVMTNDITAPLAIKEFKKTGLE--KVFDPNKVV 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+PDH++ +D++A ++R+F EQG YF G+ HV L + G
Sbjct: 61 FVPDHFVPAKDIKAAEQAKVMREFAVEQGAVYF-----------EVGRAGIEHVVLPENG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
T PG+V+ G DSHTC GAF FATG+G++D M G
Sbjct: 110 LTLPGQVIIGGDSHTCTYGAFNAFATGMGSTDIAAAMALG 149
[89][TOP]
>UniRef100_A0RXN9 3-isopropylmalate dehydratase large subunit n=1 Tax=Cenarchaeum
symbiosum RepID=A0RXN9_CENSY
Length = 429
Score = 117 bits (292), Expect = 7e-25
Identities = 66/167 (39%), Positives = 91/167 (54%), Gaps = 3/167 (1%)
Frame = +3
Query: 42 VKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDA-- 215
+K + +TEKILA+A+ R SV PGD I+ + D M HDV GPG + VF+R G+
Sbjct: 1 MKDIAAVNVTEKILARASGRESVSPGDVIFADVDKAMVHDVSGPGVMKVFERISGQGVDT 60
Query: 216 -KVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKG 392
K+WD KV I DH++ + D + N+ L+DF GI R +K G
Sbjct: 61 KKLWDPSKVWIAEDHFVPSADKISAGNIIKLQDFARNYGI--------RRHFKYGMGQYG 112
Query: 393 VCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVM 533
+CH +E PGEV G DSHT GA G FA G+G++D +V+
Sbjct: 113 ICHTLSHEEALVLPGEVYVGGDSHTNTTGALGAFACGLGHTDMAYVL 159
[90][TOP]
>UniRef100_A4J182 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum reducens MI-1 RepID=A4J182_DESRM
Length = 418
Score = 116 bits (291), Expect = 9e-25
Identities = 58/161 (36%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEK+LA AA + SV+PG+ I D+++ +D+ P I F++ G D KVWD +V
Sbjct: 1 MTITEKVLAAAAGKESVKPGELINAKVDLVLANDITAPVAIKEFQK-IGLD-KVWDKNRV 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ ++RDF + Q + ++++ G+ H L ++
Sbjct: 59 ALVPDHFTPNKDIKSAEQAKLVRDFAHTQELANYFEV----------GRMGIEHCLLPEQ 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G FATG+G++D M G
Sbjct: 109 GLVGPGDVIIGADSHTCTYGALGAFATGVGSTDLAAAMALG 149
[91][TOP]
>UniRef100_C3WDK0 Homoaconitate hydratase n=1 Tax=Fusobacterium mortiferum ATCC 9817
RepID=C3WDK0_FUSMR
Length = 424
Score = 116 bits (291), Expect = 9e-25
Identities = 60/161 (37%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILA+AA+ V+ GD +WV+ D M D+ GP I + ++ + K+W+ + V
Sbjct: 1 MTLTEKILARAAKLDKVKAGDIVWVDVDKAMMDDILGP-RIEIAEKMKELNLKIWNPDNV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
II DHY + V RD+ E +K++Y+ + G CH + ++
Sbjct: 60 TIISDHYTPPANAHQASIVKFTRDWAKENEVKHYYE------------FAGPCHQVMIEK 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PGE++ GTDSHTC GA G F+TGIG+++ V+ TG
Sbjct: 108 SRVLPGEIILGTDSHTCTYGALGAFSTGIGSTEMLGVLATG 148
[92][TOP]
>UniRef100_B0NJ74 Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC
35704 RepID=B0NJ74_EUBSP
Length = 424
Score = 116 bits (291), Expect = 9e-25
Identities = 60/161 (37%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I DV+M +D+ GP + VF++ KV+D +KV
Sbjct: 3 MTMTQKILAAHAGLDSVEAGQLIEAKLDVVMANDITGPMAVPVFRQMAD---KVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
+++PDH+ +D+++ N +R+F EQG+ ++Y++ G+ H L ++
Sbjct: 60 ILVPDHFTPNKDIKSAENSKSIREFAKEQGLTHYYEVGQM----------GIEHAILPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G T GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 110 GITVAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMATG 150
[93][TOP]
>UniRef100_A8UWH6 3-isopropylmalate dehydratase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1
RepID=A8UWH6_9AQUI
Length = 432
Score = 116 bits (291), Expect = 9e-25
Identities = 59/161 (36%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A R V+PGD I D+ M +DV P I + ++ G D +V+D K+
Sbjct: 3 MTITEKILADHAGRKEVKPGDLITAKIDLAMANDVTAPLAIKILEKH-GID-RVFDPNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ H++ +D+++ ++R+FV + GIKYF++ + +G+ H L +
Sbjct: 61 ALVLSHFVPAKDIKSAEQAKLVREFVRKHGIKYFFE-----------EGEGIEHTILPER 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G FATG+G++D + M TG
Sbjct: 110 GIVVPGDLVVGADSHTCTYGGIGAFATGVGSTDIAYAMATG 150
[94][TOP]
>UniRef100_A3CWX5 3-isopropylmalate dehydratase, large subunit n=1 Tax=Methanoculleus
marisnigri JR1 RepID=A3CWX5_METMJ
Length = 417
Score = 116 bits (290), Expect = 1e-24
Identities = 62/160 (38%), Positives = 94/160 (58%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EK+ ++ R SVR G+ + D M HD+ GP + VF+ GE +V+D E+++
Sbjct: 4 TIAEKVFSQRCGR-SVRAGEVVMAPVDAAMIHDITGPLAVRVFREMGGE--RVFDPERII 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH + + + A N +R F +EQGI + YD+ + GVCH + ++G
Sbjct: 61 MLFDHQVPADSIPAAENHVFMRRFADEQGI-HNYDLLE-----------GVCHQVVMEKG 108
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PGE++ GTDSHTC GA G FATGIG++D GFV+ G
Sbjct: 109 RAAPGEIIVGTDSHTCTYGAAGAFATGIGSTDMGFVLKFG 148
[95][TOP]
>UniRef100_A8TFZ8 3-isopropylmalate dehydratase n=1 Tax=Methanococcus voltae A3
RepID=A8TFZ8_METVO
Length = 424
Score = 116 bits (290), Expect = 1e-24
Identities = 64/161 (39%), Positives = 89/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKI++K R V G+ + V+ D+ MTHD P T+ F++ KVW+ +K+
Sbjct: 1 MTLAEKIMSKKMGR-EVVAGETVEVDVDIAMTHDGTTPLTVKTFEKIAN---KVWNPDKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH + +A I R+FVNEQGIK +Y +G+CH L +
Sbjct: 57 VIVFDHNVPANTAKAANMQVITRNFVNEQGIKNYYK-----------GGEGICHQLLPEN 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH P ++ G DSHTC GAFG FATG G +D G++ G
Sbjct: 106 GHVLPNTIITGGDSHTCTHGAFGAFATGFGATDMGYIYAMG 146
[96][TOP]
>UniRef100_Q2RG98 3-isopropylmalate dehydratase large subunit n=1 Tax=Moorella
thermoacetica ATCC 39073 RepID=LEUC_MOOTA
Length = 421
Score = 115 bits (289), Expect = 2e-24
Identities = 62/161 (38%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A +V PG I D+ + +D+ P I FK+ + KV+D E+V
Sbjct: 3 MTITEKILAAHAGLKAVEPGQLINAKVDLALGNDITAPLAIQEFKKLGVK--KVFDPERV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ ILRDF EQG+ ++++I G+ H L +
Sbjct: 61 VLVPDHFTPAKDIKSAEQAKILRDFAREQGLTHYFEI----------GRMGIEHCLLPEA 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GLVGPGDLVIGADSHTCTYGALGAFATGVGSTDLAAAMATG 151
[97][TOP]
>UniRef100_Q1LAU9 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ralstonia
metallidurans CH34 RepID=Q1LAU9_RALME
Length = 440
Score = 115 bits (288), Expect = 2e-24
Identities = 61/162 (37%), Positives = 85/162 (52%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P TL +K++A+AA V PG + D+ M+HD GP + RE G AKVWD +
Sbjct: 16 PATLAQKLVARAAGVSHVTPGSVVMCKVDLAMSHDSSGPRRVAPLLRELG--AKVWDPSR 73
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V++ DHY+ D A + RD+V E GI+ F D +G+CHV L +
Sbjct: 74 FVVVTDHYVPAADPEAESILRFTRDWVREAGIQNFID------------NEGICHVVLPE 121
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG + G DSH+ GAFG + GIG ++ V+ TG
Sbjct: 122 RGHILPGRFIVGGDSHSPTGGAFGAYMFGIGATEMAGVLATG 163
[98][TOP]
>UniRef100_C0QS35 3-isopropylmalate dehydratase, large subunit n=1 Tax=Persephonella
marina EX-H1 RepID=C0QS35_PERMH
Length = 428
Score = 114 bits (285), Expect = 4e-24
Identities = 59/161 (36%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILA+ A R V PG+ + V D+ + +D+ P I ++ +G D +V D EK+
Sbjct: 3 MTLTEKILAEHAGRDFVEPGELVTVKVDLAIANDITAPLAIKQLEK-YGID-RVHDPEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D+ + + + I RDF + GIK +++ D GV H L ++
Sbjct: 61 ALVMDHFFPPKDILSAQQIKISRDFAKKMGIKNYFEGQD----------SGVMHTILPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F+TG+G++D ++ TG
Sbjct: 111 GFIVPGDLVMGADSHTCTYGALGAFSTGVGSTDIAYIFATG 151
[99][TOP]
>UniRef100_Q24XT4 3-isopropylmalate dehydratase large subunit n=2
Tax=Desulfitobacterium hafniense RepID=LEUC_DESHY
Length = 421
Score = 114 bits (285), Expect = 4e-24
Identities = 63/161 (39%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+ A V PG I D+ + +D+ GP +I F++ FG + VWD KV
Sbjct: 3 MTITEKILAEHAGLDKVVPGQLITAQLDLALANDITGPVSIREFEK-FGVET-VWDKTKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+ + LR+F +QGI ++++ GV H L ++
Sbjct: 61 ALVPDHFTPNKDIASAELSKALREFAKKQGIVHYWE----------QGRVGVEHCLLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G T PG+V+ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GVTLPGDVIIGADSHTCTYGALGAFATGVGSTDLAAGMATG 151
[100][TOP]
>UniRef100_B8FMM4 3-isopropylmalate dehydratase large subunit n=1
Tax=Desulfatibacillum alkenivorans AK-01
RepID=LEUC_DESAA
Length = 419
Score = 114 bits (285), Expect = 4e-24
Identities = 60/161 (37%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA A + PGD I D+ + +D+ P I +F++ AKV+D ++V
Sbjct: 3 MTIAEKILAAHAGQEEASPGDLINAKVDIALGNDITAPIAIKLFRQSGA--AKVFDKDRV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ T+D+ + V ++RDF EQ + ++Y+ D GV H L ++
Sbjct: 61 VLVPDHFTPTKDINSAMQVKMVRDFAREQELSHWYEGGD----------SGVEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G FATG+G++D M TG
Sbjct: 111 GIVGPGDLVIGADSHTCTYGGLGAFATGVGSTDLAAAMITG 151
[101][TOP]
>UniRef100_B1I1Y2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Candidatus
Desulforudis audaxviator MP104C RepID=B1I1Y2_DESAP
Length = 420
Score = 113 bits (283), Expect = 8e-24
Identities = 57/161 (35%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+AA R V PG+ I D ++ +D+ P I F++ E +V+D ++V
Sbjct: 3 MTITEKILARAAGRDRVAPGELISARVDAVLGNDITAPLAIREFEKIGVE--RVFDKDRV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ +R+F QG+ Y++++ G+ H L ++
Sbjct: 61 YLVPDHFTPNKDIKSAEQAKEMREFARRQGLTYYFEV----------GRMGIEHCLLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G FATG+G++D M G
Sbjct: 111 GLVGPGDVIIGADSHTCTYGALGAFATGVGSTDLAAAMALG 151
[102][TOP]
>UniRef100_C0C2K0 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0C2K0_9CLOT
Length = 417
Score = 113 bits (283), Expect = 8e-24
Identities = 60/161 (37%), Positives = 91/161 (56%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGT-IGVFKREFGEDAKVWDTEKV 239
T+ EKI+A+AA+ VRPGD +W + D M D+ GP I +E G+ VW+ +KV
Sbjct: 4 TIAEKIIARAAKEPEVRPGDIVWADVDRAMMDDILGPRIQIAEQLKELGKP--VWNPDKV 61
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DHY + V R++ + GI+ +Y+ ++G CH +A+
Sbjct: 62 VIISDHYTPPASIHQAEIVKFTREWAADNGIQKYYE------------FEGPCHQVMAET 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G+ RPG V+ GTDSHTC GA FA+G+G+++ ++ TG
Sbjct: 110 GNVRPGMVVLGTDSHTCMGGALNAFASGVGSTEMLGILVTG 150
[103][TOP]
>UniRef100_B9LMV9 3-isopropylmalate dehydratase n=1 Tax=Halorubrum lacusprofundi ATCC
49239 RepID=B9LMV9_HALLT
Length = 437
Score = 113 bits (283), Expect = 8e-24
Identities = 61/163 (37%), Positives = 92/163 (56%)
Frame = +3
Query: 54 TPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTE 233
T T++EK+L++ + R VR GD + DV+MTHDV GP T VF+ G+D ++ D +
Sbjct: 2 TGKTISEKLLSEKSGR-DVRAGDYVEAEVDVMMTHDVTGPLTFEVFEDVTGDDPELVDPD 60
Query: 234 KVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALA 413
VI DH+ + V A N +I+R+F + G + YD+ D G+CH L
Sbjct: 61 NTVITIDHHAPADGVEAANNHNIVREFADTYGAQQ-YDVGD-----------GICHQVLV 108
Query: 414 QEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+EG PG+++ G DSH+ G G F TG+G++D G + TG
Sbjct: 109 EEGFVSPGDLVIGADSHSTTFGGVGGFGTGVGSTDLGTTLATG 151
[104][TOP]
>UniRef100_B5YKE0 3-isopropylmalate dehydratase large subunit n=1
Tax=Thermodesulfovibrio yellowstonii DSM 11347
RepID=LEUC_THEYD
Length = 421
Score = 113 bits (283), Expect = 8e-24
Identities = 58/161 (36%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA A + V PG+ I D+++ +D+ P I F++ +D V+D E++
Sbjct: 3 MTIAEKILAAHAGKKEVTPGEIINAKVDIVLANDITAPIAIKEFEKLGVKD--VFDRERI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D++A +LR+F + IK++++I G+ H L +E
Sbjct: 61 ALVPDHFTPQKDIKAAEQCKMLREFAQKYKIKHYFEI----------GRVGIEHALLPEE 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++DA M TG
Sbjct: 111 GIVLPGDLVIGADSHTCTYGALGAFATGVGSTDAAIAMATG 151
[105][TOP]
>UniRef100_C0BZF9 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
15053 RepID=C0BZF9_9CLOT
Length = 431
Score = 113 bits (282), Expect = 1e-23
Identities = 60/161 (37%), Positives = 89/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G I DV+M +D+ GP + VF + KV+D EKV
Sbjct: 10 MTMTQKILAAHAGLDHVEAGQLIEAKLDVVMANDITGPMAVPVFNQMAD---KVFDREKV 66
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ N +R+F QG+ ++Y++ G+ H L ++
Sbjct: 67 VLVPDHFTPNKDIKSAENSKSIREFARAQGLTHYYEVGQM----------GIEHALLPEK 116
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G T GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 117 GITVAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMATG 157
[106][TOP]
>UniRef100_B2UYH6 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum E3 str. Alaska E43 RepID=LEUC_CLOBA
Length = 419
Score = 113 bits (282), Expect = 1e-23
Identities = 62/161 (38%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ G I VN D+++ +D+ P I FK+ FG D KV++ ++
Sbjct: 3 MTMTQKILASHAGLESVKAGQLIEVNLDLVLGNDITTPVAINEFKK-FGVD-KVFNKSQI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A V +R+F N+ GI+ F+++ + G+ H L ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQVKYVREFSNKMGIENFFEVGEM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[107][TOP]
>UniRef100_A4XJ48 3-isopropylmalate dehydratase large subunit n=1
Tax=Caldicellulosiruptor saccharolyticus DSM 8903
RepID=LEUC_CALS8
Length = 429
Score = 113 bits (282), Expect = 1e-23
Identities = 58/165 (35%), Positives = 99/165 (60%)
Frame = +3
Query: 48 IATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWD 227
++ PMT+++KILA A + V PGD I+ N D+++ +DV P I F++ G D KV+D
Sbjct: 1 MSKPMTMSQKILAYHAGKEYVEPGDLIFANVDLVLGNDVTTPVAIKEFEK-IGVD-KVFD 58
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
+K+ I+PDH+ +D+++ + ++R+F + I ++++ + G+ H
Sbjct: 59 KDKITIVPDHFTPNKDIKSAQQCKMVREFAKKYDITNYFEVGEM----------GIEHAL 108
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
L ++G PG+++ G DSHTC GA G F+TGIG++D M TG
Sbjct: 109 LPEKGLVVPGDLVIGADSHTCTYGALGAFSTGIGSTDMACAMATG 153
[108][TOP]
>UniRef100_C0WAT0 3-isopropylmalate dehydratase n=1 Tax=Acidaminococcus sp. D21
RepID=C0WAT0_9FIRM
Length = 418
Score = 112 bits (281), Expect = 1e-23
Identities = 61/161 (37%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A + V+PGD I D ++ +D+ P I F++ V+D +++
Sbjct: 3 MTMTQKILAKHAGKDLVKPGDLITCRLDRVLANDITAPPAIKEFEKI---GRPVFDKDRI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+I +D+++ I+RDF I ++Y+ T R+ G+ HV L ++
Sbjct: 60 VLVPDHFIPNKDIKSAGLAKIVRDFAKAHHITHYYE-TGRA---------GIEHVILPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG + G DSHTC GA G FATG+G++D G M TG
Sbjct: 110 GIVGPGMLTIGADSHTCTYGALGGFATGVGSTDLGAAMATG 150
[109][TOP]
>UniRef100_B7APF9 Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus
ATCC 43243 RepID=B7APF9_9BACE
Length = 415
Score = 112 bits (281), Expect = 1e-23
Identities = 66/167 (39%), Positives = 96/167 (57%)
Frame = +3
Query: 42 VKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKV 221
++I+ TL EKI+ K + V+PG + VN D +M HD+ P + F E G KV
Sbjct: 1 MEISMGHTLIEKIVMKNTGKADVKPGAIVTVNVDRVMIHDIFIPFVVDKF-HEMGFK-KV 58
Query: 222 WDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCH 401
WD +KVV+I DH + T V R+ I FV EQG+K F+ R+D G+CH
Sbjct: 59 WDADKVVLIYDHLVPTSAVEDVRHFKIGDAFVKEQGLKNFH----RAD--------GICH 106
Query: 402 VALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ + G+ +PG ++FGTDSHT G+ G F++GIG ++ V+GTG
Sbjct: 107 QLMPEMGYAKPGNIVFGTDSHTTTYGSVGCFSSGIGYTEMAAVLGTG 153
[110][TOP]
>UniRef100_A1HUD1 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HUD1_9FIRM
Length = 419
Score = 112 bits (281), Expect = 1e-23
Identities = 62/162 (38%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGT-IGVFKREFGEDAKVWDTEK 236
MT+ EKI+A+AA + V+PG+ +W N D M D+ GP I + G+ ++WD EK
Sbjct: 3 MTMAEKIIARAANKRQVKPGEFVWANVDTAMMDDLLGPRVVIAEHIKRLGD--QIWDKEK 60
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
VVII DHY ++ + R++ E GI +Y+ G CH LA+
Sbjct: 61 VVIISDHYSPAANITQAEILQFTRNWAKEYGINKYYEGL------------GPCHQVLAE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PG ++ GTDSHT AGAFG F TGIG+++ V+ +G
Sbjct: 109 KGFDIPGTLMVGTDSHTTTAGAFGCFGTGIGSTEMLGVLVSG 150
[111][TOP]
>UniRef100_B2TIQ9 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
botulinum B str. Eklund 17B RepID=LEUC_CLOBB
Length = 419
Score = 112 bits (281), Expect = 1e-23
Identities = 62/161 (38%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ G I VN D+++ +D+ P I FK+ FG D KV++ ++
Sbjct: 3 MTMTQKILAAHAGLESVKAGQLIEVNLDLVLGNDITTPVAINEFKK-FGVD-KVFNKSQI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A V +R+F N+ GI+ F+++ + G+ H L ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQVKYVREFSNKMGIENFFEVGEM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[112][TOP]
>UniRef100_Q3ZXI5 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. CBDB1 RepID=Q3ZXI5_DEHSC
Length = 416
Score = 112 bits (279), Expect = 2e-23
Identities = 60/161 (37%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M L EKILA + V PGD I D+++ +D+ P I FK+ +KV+D++K+
Sbjct: 1 MNLVEKILAAHCGKTQVSPGDFINAKVDLVLANDITAPIAIKEFKKV--GISKVFDSKKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH++ +D+ + V ++R+F EQGI +F GV HV L ++
Sbjct: 59 VFVPDHFVPNKDIASAEQVKMVREFAREQGILFF-----------ECGKMGVEHVILHEQ 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F TG+G++D M TG
Sbjct: 108 GLVLPGDIVVGADSHTCTYGALGAFTTGMGSTDIAAAMATG 148
[113][TOP]
>UniRef100_A5FR41 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. BAV1 RepID=A5FR41_DEHSB
Length = 416
Score = 112 bits (279), Expect = 2e-23
Identities = 60/161 (37%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M L EKILA + V PGD I D+++ +D+ P I FK+ +KV+D++K+
Sbjct: 1 MNLVEKILAAHCGKTQVSPGDFINAKVDLVLANDITAPIAIKEFKKV--GVSKVFDSKKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH++ +D+ + V ++R+F EQGI +F GV HV L ++
Sbjct: 59 VFVPDHFVPNKDIASAEQVKMVREFAREQGILFF-----------ECGKMGVEHVILHEQ 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F TG+G++D M TG
Sbjct: 108 GLVLPGDIVVGADSHTCTYGALGAFTTGMGSTDIAAAMATG 148
[114][TOP]
>UniRef100_Q0AV21 3-isopropylmalate dehydratase, large subunit n=1 Tax=Syntrophomonas
wolfei subsp. wolfei str. Goettingen RepID=Q0AV21_SYNWW
Length = 419
Score = 111 bits (278), Expect = 3e-23
Identities = 60/161 (37%), Positives = 94/161 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILA+ A R + PG+ I D+++ +DV P I FK+ G D KV+D +V
Sbjct: 3 MTISQKILARHAGRKMLEPGELINCQLDLVLGNDVTAPVAIAEFKK-LGID-KVYDQSRV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ ILRDF + I+ +++I G+ H L ++
Sbjct: 61 VLVPDHFTPNKDIKSAEQCKILRDFARQYEIENYFEIGQM----------GIEHCLLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GLVVPGDLIIGADSHTCTYGALGAFATGVGSTDMAAGMATG 151
[115][TOP]
>UniRef100_A1HRB9 Homoaconitate hydratase family protein n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HRB9_9FIRM
Length = 420
Score = 111 bits (278), Expect = 3e-23
Identities = 61/160 (38%), Positives = 87/160 (54%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T++EKILAKAA + GD +WVN D M D+ GP K + +D +VWD +KVV
Sbjct: 4 TMSEKILAKAAGVPTATAGDILWVNVDKAMMDDILGPRVEIAEKMKEIKD-EVWDRDKVV 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
II DHY ++ V RD+ G+ +Y+ + G CH + + G
Sbjct: 63 IISDHYTPPATIKQAEIVKFTRDWAKTHGVANYYE------------FIGPCHQVMVEYG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H PG V+ GTDSHTC GA G FA+G+G+++ ++ TG
Sbjct: 111 HVLPGTVVLGTDSHTCMGGALGAFASGVGSTEMLGILLTG 150
[116][TOP]
>UniRef100_B5IER5 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IER5_9EURY
Length = 418
Score = 111 bits (278), Expect = 3e-23
Identities = 65/161 (40%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILAK A + V+PG+ + V +M+HD + FK+ + KVW+ +K+
Sbjct: 3 MTLTEKILAKKAGKKEVQPGEIVTVEPTWVMSHDNSA-AILLKFKKTGVK--KVWNPKKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH + N +R+FV EQGI+ F+DI G+CH +A++
Sbjct: 60 VIILDHTVPAPTADYANNHKSIREFVKEQGIENFWDINT-----------GICHQVMAEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G+ PG V+ G DSHT GAFG FA GIG S+ + TG
Sbjct: 109 GYDLPGAVIVGADSHTTTPGAFGAFAAGIGRSEVAAIWATG 149
[117][TOP]
>UniRef100_B5IEF0 Homoaconitate hydratase family protein n=1 Tax=Aciduliprofundum
boonei T469 RepID=B5IEF0_9EURY
Length = 418
Score = 111 bits (278), Expect = 3e-23
Identities = 65/161 (40%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLTEKILAK A + V+PG+ + V +M+HD + FK+ + KVW+ +K+
Sbjct: 3 MTLTEKILAKKAGKKEVQPGEIVTVEPTWVMSHDNSA-AILLKFKKTGVK--KVWNPKKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DH + N +R+FV EQGI+ F+DI G+CH +A++
Sbjct: 60 VIILDHTVPAPTADYANNHKSIREFVKEQGIENFWDINT-----------GICHQVMAEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G+ PG V+ G DSHT GAFG FA GIG S+ + TG
Sbjct: 109 GYDLPGAVIVGADSHTTTPGAFGAFAAGIGRSEVAAIWATG 149
[118][TOP]
>UniRef100_Q3Z894 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides ethenogenes 195 RepID=Q3Z894_DEHE1
Length = 416
Score = 111 bits (277), Expect = 4e-23
Identities = 60/161 (37%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M L EKILA + + V PGD I D+++ +D+ P + FK+ G +KV+D +K+
Sbjct: 1 MNLVEKILAAHSGKTQVSPGDFINAKVDLVLANDITAPIAVKEFKK-IGV-SKVFDPKKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH++ +D+ + V ++R+F EQGI +F GV HV L ++
Sbjct: 59 VFVPDHFVPNKDIASAEQVKMVREFAREQGILFF-----------ECGKMGVEHVILHEQ 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F TG+G++D M TG
Sbjct: 108 GLVLPGDIVVGADSHTCTYGALGAFTTGMGSTDIAAAMATG 148
[119][TOP]
>UniRef100_B9KB94 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Thermotoga
neapolitana DSM 4359 RepID=B9KB94_THENN
Length = 417
Score = 111 bits (277), Expect = 4e-23
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKIL+K A R V G+ + + D+ + +D+ GP I FK G+ K D +V
Sbjct: 1 MTLAEKILSKKAGR-KVETGEFLLLEPDIALANDITGPLAIKKFKEYGGKRVKYPD--RV 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ V ++R+F EQGI+ F++I G+ HV L +E
Sbjct: 58 VLVPDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEI----------GRMGIEHVLLPEE 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD-AGFVM 533
G + G+++ G DSHTC GA G FATG+G++D AGF +
Sbjct: 108 GIVKSGDLVVGADSHTCTYGALGAFATGVGSTDIAGFYL 146
[120][TOP]
>UniRef100_A5IJM1 3-isopropylmalate dehydratase, large subunit n=2 Tax=Thermotogaceae
RepID=A5IJM1_THEP1
Length = 417
Score = 111 bits (277), Expect = 4e-23
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKIL++ A R V PG+ + + DV + +D+ P I FK G+ K D +V
Sbjct: 1 MTLAEKILSQKAGR-KVEPGEFLLLEPDVALANDITAPLAIKKFKEYGGKKVKYPD--RV 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ V ++R+F EQGI+ F++I G+ HV L +E
Sbjct: 58 VLVPDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEI----------GRMGIEHVLLPEE 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD-AGFVM 533
G + G+++ G DSHTC GA G FATG+G++D AGF +
Sbjct: 108 GIVKSGDLVVGADSHTCTYGALGAFATGVGSTDIAGFYL 146
[121][TOP]
>UniRef100_A8CP51 3-isopropylmalate dehydratase, large subunit n=1
Tax=Dehalococcoides sp. VS RepID=A8CP51_9CHLR
Length = 416
Score = 111 bits (277), Expect = 4e-23
Identities = 60/161 (37%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M L EKILA + + V PGD I D+++ +D+ P + FK+ G +KV+D +K+
Sbjct: 1 MNLVEKILAAHSGKTQVSPGDFINAKVDLVLANDITAPIAVKEFKK-IGV-SKVFDPKKI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH++ +D+ + V ++R+F EQGI +F GV HV L ++
Sbjct: 59 VFVPDHFVPNKDIASAEQVKMVREFAREQGILFF-----------ECGKMGVEHVILHEQ 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F TG+G++D M TG
Sbjct: 108 GLVLPGDIVVGADSHTCTYGALGAFTTGMGSTDIAAAMATG 148
[122][TOP]
>UniRef100_Q8U2A1 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
furiosus RepID=LEUC1_PYRFU
Length = 424
Score = 111 bits (277), Expect = 4e-23
Identities = 62/161 (38%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA A + V+PG+ + D + +DV P I F R+ G + KV+D E++
Sbjct: 4 MTIAEKILATHAGKEEVKPGEIVLAKVDFMFGNDVTTPLAIKTF-RKIGVE-KVFDPERI 61
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH+ +D++A R+F EQGIK+F++ + GV H L +
Sbjct: 62 AIVLDHFTPNKDIKAAEQCKFSREFAREQGIKWFFEGGN----------VGVEHCLLPEL 111
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGE++ G DSHTC GA G FATG+G++D M TG
Sbjct: 112 GLVLPGELIIGADSHTCTYGALGAFATGVGSTDLAVAMATG 152
[123][TOP]
>UniRef100_C7I822 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermotoga
naphthophila RKU-10 RepID=C7I822_9THEM
Length = 417
Score = 110 bits (276), Expect = 5e-23
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKIL++ A R V PG+ + + D+ + +D+ P I FK G+ K D +V
Sbjct: 1 MTLAEKILSQKAGR-KVEPGEFLLLEPDIALANDITAPLAIKKFKEYGGKKVKYPD--RV 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ V ++R+F EQGI+ F++I G+ HV L +E
Sbjct: 58 VLVPDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEI----------GRMGIEHVLLPEE 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD-AGFVM 533
G + G+++ G DSHTC GA G FATG+G++D AGF +
Sbjct: 108 GIVKSGDLVVGADSHTCTYGALGAFATGVGSTDIAGFYL 146
[124][TOP]
>UniRef100_B0TCR2 3-isopropylmalate dehydratase large subunit n=1 Tax=Heliobacterium
modesticaldum Ice1 RepID=LEUC_HELMI
Length = 420
Score = 110 bits (276), Expect = 5e-23
Identities = 59/161 (36%), Positives = 92/161 (57%), Gaps = 2/161 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A + SV PG+ I D+++ +DV P + + + E V+D E+V
Sbjct: 3 MTITEKILAAHAGKASVEPGELIQAKLDLVLANDVTAP--VSIKELEKASLDAVFDKERV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH++ +D+++ I+RDF + I + YD+ D G+ H L ++
Sbjct: 61 VLVQDHFVPAKDIKSAEQSKIVRDFARKHDITHHYDVGDM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G PG+ + G DSHTC GA G FATG+G++D AG +G
Sbjct: 111 GLVVPGDAVIGADSHTCTYGALGAFATGVGSTDLAAGIALG 151
[125][TOP]
>UniRef100_B9MLV4 3-isopropylmalate dehydratase large subunit n=1 Tax=Anaerocellum
thermophilum DSM 6725 RepID=LEUC_ANATD
Length = 429
Score = 110 bits (276), Expect = 5e-23
Identities = 57/162 (35%), Positives = 97/162 (59%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMT+++KILA A + V PGD I+ N D+++ +DV P I F++ G D +V+D +K
Sbjct: 4 PMTMSQKILAYHAGKEYVEPGDLIFANVDLVLGNDVTTPVAIKEFEK-IGID-RVFDKDK 61
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ I+PDH+ +D+++ + ++R+F + I ++++ + G+ H L +
Sbjct: 62 IAIVPDHFTPNKDIKSAQQCKMVREFAKKYEITNYFEVGEM----------GIEHALLPE 111
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PG+++ G DSHTC GA G F+TGIG++D M TG
Sbjct: 112 KGLVVPGDLVIGADSHTCTYGALGAFSTGIGSTDMACAMATG 153
[126][TOP]
>UniRef100_Q9WZ24 3-isopropylmalate dehydratase large subunit 2 n=2 Tax=Thermotoga
RepID=LEUC2_THEMA
Length = 417
Score = 110 bits (276), Expect = 5e-23
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL EKIL++ A R V PG+ + + D+ + +D+ P I FK G+ K D +V
Sbjct: 1 MTLAEKILSQKAGR-KVEPGEFLLLEPDIALANDITAPLAIKKFKEYGGKKVKYPD--RV 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ V ++R+F EQGI+ F++I G+ HV L +E
Sbjct: 58 VLVPDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEI----------GRMGIEHVLLPEE 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD-AGFVM 533
G + G+++ G DSHTC GA G FATG+G++D AGF +
Sbjct: 108 GIVKSGDLVVGADSHTCTYGALGAFATGVGSTDIAGFYL 146
[127][TOP]
>UniRef100_Q1Q122 Similar to 3-isopropylmalate dehydratase, large subunit n=1
Tax=Candidatus Kuenenia stuttgartiensis
RepID=Q1Q122_9BACT
Length = 437
Score = 110 bits (275), Expect = 6e-23
Identities = 57/161 (35%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI+A VRPG ++ N DV + +D+ P I F++ KV+D EK+
Sbjct: 10 MTITEKIIAAHCGEREVRPGQFVYANVDVCLGNDITAPIAIEEFEK--AGIKKVFDPEKI 67
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ + LR F + +K++++I G+ H L ++
Sbjct: 68 VLVPDHFTPNKDIQSAQQSKSLRVFAEKHHLKHYFEI----------GRMGIEHALLPEQ 117
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGE++ G DSHTC GA G F+TGIG++D TG
Sbjct: 118 GIVAPGELVIGADSHTCTYGALGAFSTGIGSTDLAACFATG 158
[128][TOP]
>UniRef100_A7B6Z9 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
29149 RepID=A7B6Z9_RUMGN
Length = 425
Score = 110 bits (275), Expect = 6e-23
Identities = 59/161 (36%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I D++M +D+ GP + + K+ + V+D EKV
Sbjct: 3 MTMTQKILAAHAGLESVTAGQLIEAKLDIVMANDITGPMALPILKQMADQ---VFDKEKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH+ +D+++ N +R+F EQG+K++++ GV H L +
Sbjct: 60 VFVPDHFTPNKDIKSAENSKAIREFAKEQGLKWYFE----------QGKSGVEHAILPEA 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 110 GVVTAGECIIGADSHTCTYGALGAFSTGMGTTDIATGMATG 150
[129][TOP]
>UniRef100_A1HLS2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HLS2_9FIRM
Length = 420
Score = 110 bits (275), Expect = 6e-23
Identities = 57/161 (35%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA+ A + +V PG I D+++ +D+ P I F+R V+D K+
Sbjct: 3 MTMTEKILARHAGQAAVVPGQLIRCRVDLILGNDITAPPAIQEFERI---GRPVFDPSKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ + +R+F + GI +++++ G+ HV L +
Sbjct: 60 ALVPDHFAPNKDIKSAQMCKTMREFAVKHGITHYFEV----------GRMGIEHVLLPEV 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGEV+ G DSHTC GA G FATG+G++D M TG
Sbjct: 110 GLVAPGEVIIGADSHTCTYGALGAFATGVGSTDMAAAMATG 150
[130][TOP]
>UniRef100_A6UTS7 3-isopropylmalate dehydratase n=1 Tax=Methanococcus aeolicus
Nankai-3 RepID=A6UTS7_META3
Length = 421
Score = 110 bits (275), Expect = 6e-23
Identities = 64/161 (39%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL E+IL+K + V+ GD + ++ D+ MTHD P + FK+ KVWD +K+
Sbjct: 1 MTLAEEILSKKVGK-KVKAGDVVEIDIDLAMTHDGTTPLSAKAFKQITD---KVWDNKKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH + ++A I R+F+ EQ I Y D +GVCH L +
Sbjct: 57 VIVFDHNVPANTLKAANMQKITREFIKEQNIINHY-----------LDGEGVCHQVLPEN 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P V+ G DSHTC GAFG FATG G +D G + TG
Sbjct: 106 GHIQPNMVIAGGDSHTCTYGAFGAFATGFGATDMGNIYATG 146
[131][TOP]
>UniRef100_C0CTF7 Putative uncharacterized protein (Fragment) n=1 Tax=Clostridium
asparagiforme DSM 15981 RepID=C0CTF7_9CLOT
Length = 279
Score = 110 bits (274), Expect = 8e-23
Identities = 62/161 (38%), Positives = 85/161 (52%), Gaps = 1/161 (0%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGT-IGVFKREFGEDAKVWDTEKV 239
T++EKI+A+A+ V D +WV+ D M DV GP I RE G D VWD +KV
Sbjct: 4 TISEKIMARASGNEQVHSDDIVWVDIDRAMMDDVLGPRLEIDDRLREMGVD--VWDPDKV 61
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VII DHY ++ V R++ E I +Y+ + G CH + +
Sbjct: 62 VIISDHYTPPANLHQANIVKFTREWAAEHKISRYYE------------FAGPCHQVMVEH 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG V+ GTDSHTC GA FATG+G+++ V+ TG
Sbjct: 110 GHVLPGSVVVGTDSHTCTYGALASFATGVGSTEMAGVLATG 150
[132][TOP]
>UniRef100_A6UQC3 Homoaconitate hydratase family protein n=1 Tax=Methanococcus
vannielii SB RepID=A6UQC3_METVS
Length = 418
Score = 110 bits (274), Expect = 8e-23
Identities = 64/161 (39%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL E IL+K + +V D++ ++ D+ MTHD P T+ F+ E + +V+D +K+
Sbjct: 1 MTLAEAILSKKLGK-NVYAKDSVEIDVDLAMTHDGTTPLTVKAFE-EISD--RVFDNKKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+ DH I +A I RDF+ + IK +Y D +G+CH L ++
Sbjct: 57 VIVFDHNIPANTSKAANMQIITRDFIKKHDIKNYY-----------LDGEGICHQILPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH +P V+ G DSHTC GAFG FATG G SD G+V TG
Sbjct: 106 GHVKPNMVIVGADSHTCTHGAFGAFATGFGASDMGYVYATG 146
[133][TOP]
>UniRef100_B2V844 3-isopropylmalate dehydratase large subunit n=1
Tax=Sulfurihydrogenibium sp. YO3AOP1 RepID=LEUC_SULSY
Length = 431
Score = 110 bits (274), Expect = 8e-23
Identities = 56/161 (34%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI+A A R V PG+ + V D+ + +D+ P I ++ +G D KV D K+
Sbjct: 3 MTITEKIIAAHAGRDYVEPGELVTVKVDLAIANDITAPLAIKQLEK-YGID-KVHDPNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D+ + + + I RDF + GIK +++ D GV H L ++
Sbjct: 61 ALVMDHFFPPKDIMSAQQIKISRDFAKKMGIKNYFEGQD----------SGVMHTLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G F+TG+G++D ++ TG
Sbjct: 111 GFVVPGDLVIGADSHTCTYGGIGAFSTGVGSTDIAYIWATG 151
[134][TOP]
>UniRef100_C5CMF0 Homoaconitate hydratase family protein n=1 Tax=Variovorax paradoxus
S110 RepID=C5CMF0_VARPS
Length = 429
Score = 109 bits (273), Expect = 1e-22
Identities = 59/160 (36%), Positives = 87/160 (54%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL +K++A+A+ R V G+ + D+ M HD GP + E G A++WD +VV
Sbjct: 14 TLAQKLIARASGRAQVAVGEIVTCGVDMAMFHDSSGPRRLQPMLEELG--AQIWDRSRVV 71
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DHY+ D + R V I RD+ EQ + + YD +G+CHV + Q G
Sbjct: 72 LVMDHYVPERDDDSRRIVRIARDWAREQQLPHVYDS------------QGICHVVVPQHG 119
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H RPG + G DSH+ GAFG + GIG+++ VM TG
Sbjct: 120 HIRPGMLCVGGDSHSPTGGAFGAYMFGIGSTEMLGVMVTG 159
[135][TOP]
>UniRef100_A0LMK9 3-isopropylmalate dehydratase, large subunit n=1
Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LMK9_SYNFM
Length = 419
Score = 109 bits (273), Expect = 1e-22
Identities = 56/162 (34%), Positives = 91/162 (56%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMT++EKILA+ + + +V P D I D + +D+ P I F++ ++V+D E+
Sbjct: 2 PMTISEKILARHSGKSTVLPDDLIEAGIDFALGNDITAPLAIEAFRKVGA--SRVFDPER 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++PDH+ +D+ + ILRDF E + +++++ GV H L +
Sbjct: 60 IALVPDHFAPNKDIASAMQCKILRDFAREWNLTHYFEV----------GRMGVEHALLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PG+V+ G DSHTC GA G FATG+G++D M TG
Sbjct: 110 QGLVLPGDVVIGADSHTCTYGALGAFATGVGSTDLAAAMITG 151
[136][TOP]
>UniRef100_B8CX22 3-isopropylmalate dehydratase large subunit n=1 Tax=Halothermothrix
orenii H 168 RepID=LEUC_HALOH
Length = 420
Score = 109 bits (273), Expect = 1e-22
Identities = 55/161 (34%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKI+A R V+PGD + D ++ +DV P + F + G D +V+D +++
Sbjct: 3 MTMIEKIIAAHTNRDKVKPGDIVNARIDFVLGNDVTTPVAVKEFNK-IGID-EVFDQDRI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ +R+F ++GI +++I + G+ H L ++
Sbjct: 61 AIVPDHFTPNKDIKSAEQCKFIREFARDKGIHNYFEIGEM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGE++ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GLALPGEIIIGADSHTCTYGALGAFATGVGSTDMAAAMATG 151
[137][TOP]
>UniRef100_UPI00016C5FE1 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile QCD-97b34 RepID=UPI00016C5FE1
Length = 425
Score = 109 bits (272), Expect = 1e-22
Identities = 59/161 (36%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A+ V+ G I + DV++ +D+ P I F++ ED V+D KV
Sbjct: 3 MTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIREFEKLGIED--VYDKTKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH+ +D+++ R F +G+ F+D+ D G+ HV L ++
Sbjct: 61 VMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDM----------GIEHVLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D G M TG
Sbjct: 111 GIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATG 151
[138][TOP]
>UniRef100_UPI00006DC4ED hypothetical protein CdifQ_04001011 n=1 Tax=Clostridium difficile
QCD-32g58 RepID=UPI00006DC4ED
Length = 230
Score = 109 bits (272), Expect = 1e-22
Identities = 59/161 (36%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A+ V+ G I + DV++ +D+ P I F++ ED V+D KV
Sbjct: 1 MTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIREFEKLGIED--VYDKTKV 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH+ +D+++ R F +G+ F+D+ D G+ HV L ++
Sbjct: 59 VMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDM----------GIEHVLLPEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D G M TG
Sbjct: 109 GIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATG 149
[139][TOP]
>UniRef100_A3DHI4 3-isopropylmalate dehydratase large subunit n=3 Tax=Clostridium
thermocellum RepID=LEUC_CLOTH
Length = 419
Score = 109 bits (272), Expect = 1e-22
Identities = 60/161 (37%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V PG I D+++ +D+ P + F R+ G + KV+D K+
Sbjct: 3 MTMTQKILADHAGLDKVSPGQLIKAKLDMVLGNDITTPVAVKEF-RKIGVN-KVFDVNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ V +R+F E GI F+++ GV H L ++
Sbjct: 61 AIVPDHFTPNKDIKSAEQVKFIREFAREMGIVNFFEVGQM----------GVEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVPGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[140][TOP]
>UniRef100_Q18AJ2 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
difficile 630 RepID=LEUC_CLOD6
Length = 425
Score = 109 bits (272), Expect = 1e-22
Identities = 59/161 (36%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A+ V+ G I + DV++ +D+ P I F++ ED V+D KV
Sbjct: 3 MTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIREFEKLGIED--VYDKTKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH+ +D+++ R F +G+ F+D+ D G+ HV L ++
Sbjct: 61 VMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDM----------GIEHVLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D G M TG
Sbjct: 111 GIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATG 151
[141][TOP]
>UniRef100_B1C4Q4 Putative uncharacterized protein n=1 Tax=Clostridium spiroforme DSM
1552 RepID=B1C4Q4_9FIRM
Length = 424
Score = 108 bits (271), Expect = 2e-22
Identities = 61/161 (37%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I DV+M +D+ GP + +F++ KV+D +KV
Sbjct: 3 MTMTQKILADHAGMESVTAGQLIEAKLDVVMANDITGPMALPIFRQMAD---KVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ N + DF NEQG+ Y + GV H L +
Sbjct: 60 VLVPDHFTPNKDIKSAENSKAILDFSNEQGLTYHME----------QGKCGVEHAILPEM 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC+ GA G F+TG+G +D M TG
Sbjct: 110 GIVVAGECIIGADSHTCSYGALGAFSTGVGTTDIATGMATG 150
[142][TOP]
>UniRef100_C1DUH4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium azorense Az-Fu1
RepID=C1DUH4_SULAA
Length = 431
Score = 108 bits (270), Expect = 2e-22
Identities = 55/161 (34%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI+A A + V PG+ + V D+ + +D+ P I ++ +G D KV D K+
Sbjct: 3 MTITEKIIAAHAGKDYVEPGELVTVKVDLAIANDITAPLAIKQLEK-YGID-KVHDPNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D+ + + + I RDF + GIK +++ D GV H L ++
Sbjct: 61 ALVMDHFFPPKDILSAQQIKISRDFAKKMGIKNYFEGQD----------SGVMHTLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G F+TG+G++D ++ TG
Sbjct: 111 GFVVPGDLVIGADSHTCTYGGIGAFSTGVGSTDIAYIWATG 151
[143][TOP]
>UniRef100_C4FI11 3-isopropylmalate dehydratase, large subunit n=1
Tax=Sulfurihydrogenibium yellowstonense SS-5
RepID=C4FI11_9AQUI
Length = 431
Score = 108 bits (270), Expect = 2e-22
Identities = 55/161 (34%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI+A A + V PG+ + V D+ + +D+ P I ++ +G D KV D K+
Sbjct: 3 MTITEKIIAAHAGKDYVEPGELVTVKVDLAIANDITAPLAIKQLEK-YGID-KVHDPNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D+ + + + I RDF + GIK +++ D GV H L ++
Sbjct: 61 ALVMDHFFPPKDIMSAQQIKISRDFAKKMGIKNYFEGQD----------SGVMHTLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G F+TG+G++D ++ TG
Sbjct: 111 GFIVPGDLVIGADSHTCTYGGIGAFSTGVGSTDIAYIWATG 151
[144][TOP]
>UniRef100_A5KNQ3 Putative uncharacterized protein n=1 Tax=Ruminococcus torques ATCC
27756 RepID=A5KNQ3_9FIRM
Length = 451
Score = 108 bits (270), Expect = 2e-22
Identities = 56/161 (34%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A +V G I D++M +D+ GP + + ++ KV+D +KV
Sbjct: 10 MTMTQKILAAHAGLDTVEAGQLIEAKLDIVMANDITGPMALPIIRQM---SDKVFDKDKV 66
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH+ +D+++ N +R++ EQG+K++++ GV H L +
Sbjct: 67 VFVPDHFTPNKDIKSAENSKAIREYAKEQGLKWYFE----------QGKSGVEHAILPEA 116
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 117 GVVTAGECIIGADSHTCTYGALGAFSTGMGTTDVATGMATG 157
[145][TOP]
>UniRef100_Q2KVM0 3-isopropylmalate dehydratase large subunit n=1 Tax=Bordetella
avium 197N RepID=Q2KVM0_BORA1
Length = 422
Score = 108 bits (269), Expect = 3e-22
Identities = 62/165 (37%), Positives = 85/165 (51%)
Frame = +3
Query: 48 IATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWD 227
+A P +L +K++A A R SV G+ + D+ M HD GP + E G AK+WD
Sbjct: 1 MAEPQSLAQKLIAAACGRSSVAEGEIVTCAVDLAMFHDSSGPRRLQPMLEELG--AKLWD 58
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
KVV++ DHY+ D + R V I RD+ EQ + YD G+CHV
Sbjct: 59 PSKVVLVIDHYVPESDDESRRIVRIARDWAAEQRLPNVYDSL------------GICHVV 106
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ Q GH RPG G DSH+ GAFG + GIG+++ V TG
Sbjct: 107 VPQHGHIRPGMFCVGGDSHSPTGGAFGAYMFGIGSTEMLGVAVTG 151
[146][TOP]
>UniRef100_Q1IZK5 3-isopropylmalate dehydratase large subunit n=1 Tax=Deinococcus
geothermalis DSM 11300 RepID=Q1IZK5_DEIGD
Length = 431
Score = 108 bits (269), Expect = 3e-22
Identities = 59/153 (38%), Positives = 90/153 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA + + V PG I TD ++ H++ P + + + E G D +V+D EK+
Sbjct: 3 MTIAEKILAAHSGQKEVVPGQLIECATDWVLCHEITTPAALRMLE-ERGMD-RVFDPEKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH + +++A + L+ +V E+GI++FYD+ G+ HV L
Sbjct: 61 VAVPDHSVPAMNIKAAKMYQKLKSWVQEKGIRHFYDV----------GRGGIAHVVLENT 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD 518
G +PG+ L DSHTCNAGA G FATG+G++D
Sbjct: 111 GLIKPGQTLVSGDSHTCNAGALGCFATGVGSTD 143
[147][TOP]
>UniRef100_C5EVL2 Putative uncharacterized protein n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EVL2_9FIRM
Length = 417
Score = 108 bits (269), Expect = 3e-22
Identities = 59/161 (36%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA +R V PG+ I + D++M DV P + +R FG D +WD++++
Sbjct: 3 MTMTQKILASHCKRSGVMPGELIHAHLDLVMGSDVTTPIALQELER-FGLDT-IWDSKRI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++ DH+ +D++A RN +R+F I +FYD G+ H L ++
Sbjct: 61 VLVMDHFAPNKDIQAARNCKKVREFAARHQISHFYD----------GGKMGIEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G P +++ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLIAPSKLIIGADSHTCTYGALGAFSTGIGSTDMAAGMITG 151
[148][TOP]
>UniRef100_UPI000196B289 hypothetical protein CATMIT_00953 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196B289
Length = 425
Score = 107 bits (268), Expect = 4e-22
Identities = 58/161 (36%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G+ I N D++M +D+ GP + +FK+ KV+D +KV
Sbjct: 3 MTMTQKILADHAGVKEVHAGELIEANVDIVMANDITGPMALPIFKKMAD---KVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ N +R+F EQG+ + + GV H L +
Sbjct: 60 VLVPDHFTPNKDIKSAENSKAIREFSREQGLTHHME----------QGKCGVEHAILPES 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+ + G DSHTC GA G F+TG+G +D M TG
Sbjct: 110 GIVVAGDAVIGADSHTCTYGAIGAFSTGVGTTDIATGMATG 150
[149][TOP]
>UniRef100_B8GJ01 Homoaconitate hydratase family protein n=1 Tax=Methanosphaerula
palustris E1-9c RepID=B8GJ01_METPE
Length = 419
Score = 107 bits (268), Expect = 4e-22
Identities = 62/160 (38%), Positives = 90/160 (56%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI + R V GD + D M HD+ GP I F + G +V+D +KV+
Sbjct: 7 TIAEKIFSTRCGR-PVHAGDVVMAPIDAAMIHDITGPLAIQTFYQMGG--TRVFDPKKVI 63
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH I + + A N ++R F EQGI + YD+ ++GVCH + ++G
Sbjct: 64 MLFDHQIPADSIAAAGNHQLMRKFAAEQGI-HNYDL-----------HEGVCHQVVLEKG 111
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PGE++ G+DSHTC GA G FATGIG++D GFV+ G
Sbjct: 112 RAGPGEIVVGSDSHTCMYGAAGAFATGIGSTDMGFVLKFG 151
[150][TOP]
>UniRef100_Q8RDK2 3-isopropylmalate dehydratase large subunit n=1
Tax=Thermoanaerobacter tengcongensis RepID=LEUC_THETN
Length = 418
Score = 107 bits (268), Expect = 4e-22
Identities = 56/161 (34%), Positives = 96/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
+TLT+KIL+ A R V+PG+ I ++ D+++ +D+ P I F++ G D KV+D K+
Sbjct: 3 LTLTQKILSAKAGR-EVKPGELIEIDVDMVLGNDITAPVAIKEFEK-IGVD-KVFDNTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH++ ++D+++ V+++R F + I F+++ G+ H L ++
Sbjct: 60 ALVPDHFVPSKDIKSAEQVNVMRKFAKKYNIVNFFEV----------GRMGIEHALLPEQ 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA FATG+G++D M TG
Sbjct: 110 GLVLPGDVVIGADSHTCTYGALTCFATGVGSTDMAAAMATG 150
[151][TOP]
>UniRef100_C5BFR8 Homoaconitate hydratase family protein, large subunit n=1
Tax=Edwardsiella ictaluri 93-146 RepID=C5BFR8_EDWI9
Length = 421
Score = 107 bits (267), Expect = 5e-22
Identities = 58/160 (36%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKILA A V GD +WV+ D M D+ GP + + ++ + E+VV
Sbjct: 4 TVAEKILAAKAGLTEVTAGDVVWVDVDKAMMDDILGP-RVQIAEQLESLKMPIRHRERVV 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DHY + R V RD+ EQGI +Y+ ++G CH +A++G
Sbjct: 63 VIADHYTPPANARQAEIVKFTRDWSAEQGIDRYYE------------FQGPCHQIMAEQG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H PG ++ GTDSHTC GA G FATG+G+++ ++ TG
Sbjct: 111 HVLPGTLILGTDSHTCMGGALGAFATGVGSTEMVGILATG 150
[152][TOP]
>UniRef100_A1WJ56 3-isopropylmalate dehydratase, large subunit n=1
Tax=Verminephrobacter eiseniae EF01-2 RepID=A1WJ56_VEREI
Length = 428
Score = 107 bits (267), Expect = 5e-22
Identities = 58/164 (35%), Positives = 89/164 (54%)
Frame = +3
Query: 51 ATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDT 230
A TL +K+LA+A+ R V G+ + + D+ M HD GP + + G A+VWD
Sbjct: 9 APARTLAQKLLARASGRAHVAVGEIVTCSVDLAMFHDSSGPRRLQPMLQALG--AQVWDR 66
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
++V++ DHY+ D ++R V I RD+ +Q + + YD +G+CHV L
Sbjct: 67 SRIVLVIDHYVPERDEDSHRIVRIARDWARDQQLPHVYDS------------QGICHVVL 114
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
Q GH RPG + G DSH GAFG + G+G+++ V+ TG
Sbjct: 115 PQNGHIRPGMLCVGGDSHAPTGGAFGAYMFGVGSTEMLGVLVTG 158
[153][TOP]
>UniRef100_A6BFK8 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
13814 RepID=A6BFK8_9FIRM
Length = 424
Score = 107 bits (267), Expect = 5e-22
Identities = 58/161 (36%), Positives = 88/161 (54%), Gaps = 2/161 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I DV+M +D+ GP + +F++ KV+D +KV
Sbjct: 3 MTMTQKILAAHAGLDSVTAGQLIEAKLDVVMANDITGPMALPIFRQMAD---KVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ N +R+F QG+ ++++ GV H L +
Sbjct: 60 VLVPDHFTPNKDIKSAENSKSIREFAKNQGLSWYFE----------QGKSGVEHAILPEA 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G GE + G DSHTC GA G F+TG+G +D G MG
Sbjct: 110 GVVAAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMAMG 150
[154][TOP]
>UniRef100_C1CVE2 Putative 3-isopropylmalate dehydratase, large subunit
(Isopropylmalate isomerase) (Alpha-IPM isomerase) n=1
Tax=Deinococcus deserti VCD115 RepID=C1CVE2_DEIDV
Length = 426
Score = 107 bits (266), Expect = 7e-22
Identities = 58/153 (37%), Positives = 89/153 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA + V PG I TD ++ H++ P + + + E G D +V++ +++
Sbjct: 3 MTIAEKILAAHSGHDQVVPGQLIECATDWVLCHEITTPAALRMLE-ERGMD-QVFNPDQI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH + +++A + L+ +V E+GIK+FYD+ G+ HV L
Sbjct: 61 VAVPDHSVPAMNIKAAKMYQKLKSWVQEKGIKHFYDV----------GRGGIAHVVLENT 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD 518
G RPG+ L DSHTCNAGA G FATG+G++D
Sbjct: 111 GLVRPGQTLVSGDSHTCNAGALGMFATGVGSTD 143
[155][TOP]
>UniRef100_Q0QLE2 2,3-dimethylmalate dehydratase large subunit n=1 Tax=Eubacterium
barkeri RepID=Q0QLE2_EUBBA
Length = 420
Score = 107 bits (266), Expect = 7e-22
Identities = 57/161 (35%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ GD I + D+++ +D+ GP I VF E KV+D +K+
Sbjct: 3 MTMTQKILAAHASLDSVKAGDLIMADLDMVLANDITGPVAINVFGTIDKE--KVFDKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ + +R F +Q I +++I + G+ H L ++
Sbjct: 61 ALVPDHFAPAKDIKSAQQCKQVRCFACDQEITNYFEIGEM----------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLVAAGDVVIGADSHTCTYGALGAFSTGVGSTDMAVGMATG 151
[156][TOP]
>UniRef100_B3TBB7 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8O8 RepID=B3TBB7_9ARCH
Length = 423
Score = 107 bits (266), Expect = 7e-22
Identities = 58/165 (35%), Positives = 88/165 (53%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDA----KVWD 227
M +TEKILA+A+ + + PGD ++ N D +M HDV GPG I F++ + K++D
Sbjct: 1 MNITEKILARASGKDKLEPGDVVFANVDKVMLHDVSGPGVIKTFEKLEKDGVVKVDKLFD 60
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
V + DH++ + D + N+ L F ++ GIK +K G+CH
Sbjct: 61 PSMVWVAEDHFVPSADKISAENISKLSKFTSKFGIK--------KHFKYGLGQYGICHTL 112
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+EG PGE+ G DSHT GA G FA G+G++D +V+ G
Sbjct: 113 SHEEGLVSPGELYIGGDSHTNTTGALGAFACGLGHTDVAYVLLNG 157
[157][TOP]
>UniRef100_B0KAH5 3-isopropylmalate dehydratase large subunit n=3
Tax=Thermoanaerobacter RepID=LEUC_THEP3
Length = 417
Score = 107 bits (266), Expect = 7e-22
Identities = 57/161 (35%), Positives = 95/161 (59%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
+TLT+KIL+ R V+PG+ I V+ D+++ +DV P I F++ G D +V+D K+
Sbjct: 3 LTLTQKILSAKVGR-EVKPGELIEVDVDMVLGNDVTAPVAIKEFEK-IGID-RVFDNTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH++ +D+++ V+I+R F + GI F+++ G+ H L ++
Sbjct: 60 ALVPDHFVPNKDIKSAEQVNIMRKFAKKHGIVNFFEVGQM----------GIEHALLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA F+TG+G++D M TG
Sbjct: 110 GLVLPGDVVIGADSHTCTYGALTCFSTGVGSTDMAAAMATG 150
[158][TOP]
>UniRef100_B5CQV8 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
29176 RepID=B5CQV8_9FIRM
Length = 424
Score = 106 bits (265), Expect = 9e-22
Identities = 57/161 (35%), Positives = 86/161 (53%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I D++M +D+ GP + + K+ V+D +KV
Sbjct: 3 MTMTQKILAAHAGLDSVEAGQLIEAKLDIVMANDITGPMALPILKQM---SDTVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH+ +D+++ N +R+F QG+K++++ GV H L +
Sbjct: 60 VFVPDHFTPNKDIKSAENSKAIREFSKAQGLKWYFE----------QGKSGVEHAILPEA 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 110 GVVTAGECIIGADSHTCTYGALGAFSTGMGTTDVATGMATG 150
[159][TOP]
>UniRef100_Q9RTI6 3-isopropylmalate dehydratase large subunit 2 n=1 Tax=Deinococcus
radiodurans RepID=LEUC2_DEIRA
Length = 431
Score = 106 bits (265), Expect = 9e-22
Identities = 57/153 (37%), Positives = 90/153 (58%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EK+LA + +V PG I TD ++ H++ P + + + E G D +V+D +K+
Sbjct: 3 MTIAEKMLAAHSGHDTVVPGQLIECATDWVLCHEITTPAALRMLE-ERGMD-RVFDPQKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH + +++A + L+ +V E+GI++FYD+ G+ HV L
Sbjct: 61 VAVPDHSVPAMNIKAAKMYQKLKSWVQEKGIEHFYDV----------GRGGIAHVVLENT 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD 518
G +PG+ L DSHTCNAGA G FATG+G++D
Sbjct: 111 GLMKPGQTLVSGDSHTCNAGALGAFATGVGSTD 143
[160][TOP]
>UniRef100_Q9UZ07 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Pyrococcus
abyssi RepID=LEUC1_PYRAB
Length = 423
Score = 106 bits (265), Expect = 9e-22
Identities = 60/161 (37%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA +ER V+PG+ + D + +DV P I F RE G +V+D E++
Sbjct: 3 MTIAEKILADHSEREEVKPGEIVMAKLDFVFGNDVTMPLAIKKF-RELGVK-RVFDRERI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH+ +D+++ R+F E GIK+F++ GV H L +
Sbjct: 61 AIVLDHFTPNKDIKSAEQCKSSREFAKEMGIKWFFE----------GGSVGVEHCLLPEL 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G FATG+G++D M TG
Sbjct: 111 GLVLPGDLIIGADSHTCTYGALGAFATGVGSTDLAVAMATG 151
[161][TOP]
>UniRef100_A5D4W1 3-isopropylmalate dehydratase large subunit n=1 Tax=Pelotomaculum
thermopropionicum SI RepID=A5D4W1_PELTS
Length = 420
Score = 106 bits (264), Expect = 1e-21
Identities = 56/161 (34%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A + V PG+ I V D+++ +D+ P I F++ G A+V+D E+V
Sbjct: 3 MTITEKILADHAGKKQVEPGELISVKVDLVLGNDITAPVAIKEFEK-IGV-AEVFDRERV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ ILR+F + + ++++ G+ H L +E
Sbjct: 61 ALVPDHFTPNKDIKSAEQSKILREFSKKHNLANYFEV----------GRAGIEHCLLPEE 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC GA G F+TG+G++D M G
Sbjct: 111 GLVGPGDLVIGADSHTCTYGALGAFSTGVGSTDLAAAMALG 151
[162][TOP]
>UniRef100_C6PDK3 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermoanaerobacterium thermosaccharolyticum DSM 571
RepID=C6PDK3_CLOTS
Length = 418
Score = 106 bits (264), Expect = 1e-21
Identities = 59/161 (36%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
+TLT+KILA A V PGD I ++ D+++ +DV P I F + ++ V+D EK+
Sbjct: 3 LTLTQKILADKAGY-DVHPGDLIEIDVDMVLGNDVTSPVAIKEFLKIGVKN--VFDKEKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH++ +D+++ V+I+R F E GI F+++ G+ H L ++
Sbjct: 60 ALVPDHFVPNKDIKSAEQVNIVRKFAREYGIVNFFEVGKM----------GIEHALLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA F+TGIG++D M TG
Sbjct: 110 GLVLPGDVVIGADSHTCTYGAITCFSTGIGSTDMACAMATG 150
[163][TOP]
>UniRef100_Q97EE0 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
acetobutylicum RepID=LEUC_CLOAB
Length = 422
Score = 106 bits (264), Expect = 1e-21
Identities = 57/162 (35%), Positives = 92/162 (56%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMT+T+KILA A V G I N D+++ +DV P + FK G + KV+D +K
Sbjct: 4 PMTMTQKILANHAGLDYVEAGQLITANLDLVLGNDVTTPVAVKAFKT-MGTN-KVFDKKK 61
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V I+PDH+ +D+++ + ++R F + I+ +++I + G+ H + +
Sbjct: 62 VAIVPDHFTPNKDIKSAEHCKMIRQFAKSKEIENYFEIGEM----------GIEHALIPE 111
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PG+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 112 KGLAVPGDVIIGADSHTCTYGALGVFSTGVGSTDMAVGMATG 153
[164][TOP]
>UniRef100_Q7W4L0 Putative 3-isopropylmalate dehydratase large subunit n=2
Tax=Bordetella RepID=Q7W4L0_BORPA
Length = 420
Score = 105 bits (263), Expect = 2e-21
Identities = 56/160 (35%), Positives = 84/160 (52%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL +K+LA AA R +VR G+ + D+ M HD GP + E G +WD ++V
Sbjct: 5 TLAQKLLAAAAGRDAVRVGEIVTCKVDLAMFHDSSGPRRLQPMLEELGTG--LWDRSRIV 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DHY+ D + R V I RD+ EQ + + YD G+CHV + + G
Sbjct: 63 LVMDHYVPESDDESRRIVRIARDWAREQALPHVYDSL------------GICHVVVPEHG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H RPG G DSH+ GAFG + G+G+++ V+ +G
Sbjct: 111 HVRPGMFCVGGDSHSPTGGAFGAYMFGVGSTEMLGVVSSG 150
[165][TOP]
>UniRef100_C4Z1K0 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit n=1
Tax=Eubacterium eligens ATCC 27750 RepID=C4Z1K0_EUBE2
Length = 413
Score = 105 bits (263), Expect = 2e-21
Identities = 62/163 (38%), Positives = 90/163 (55%), Gaps = 3/163 (1%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGED---AKVWDTE 233
T+ EKI+ K R V+PGD + VN D +M HD+ P F +E E+ K+WD +
Sbjct: 4 TIIEKIIGKNIGR-EVKPGDIVTVNVDRVMIHDIFIP-----FVKEKFEEMGFTKIWDPD 57
Query: 234 KVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALA 413
K V+I DH + V R+ I +FV E G+K + RSD G+CH +
Sbjct: 58 KAVLIYDHLVPASQVDDTRHFRIGNEFVEEYGMKNIH----RSD--------GICHQLMT 105
Query: 414 QEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ G+ +PG++ FGTDSHT G G F++GIG ++ V+GTG
Sbjct: 106 EAGYVKPGDIAFGTDSHTTTYGCVGAFSSGIGYTEMASVLGTG 148
[166][TOP]
>UniRef100_B8I4G0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
cellulolyticum H10 RepID=B8I4G0_CLOCE
Length = 419
Score = 105 bits (263), Expect = 2e-21
Identities = 59/161 (36%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A + PG I D+++ +D+ P I F + G D KV+D K+
Sbjct: 3 MTMTQKILASHAGVDKLVPGQLIMAKLDMVLGNDITSPVAIKEFDK-IGLD-KVFDKNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ V + R+F GI F+++ GV H L ++
Sbjct: 61 AIVPDHFTPNKDIKSAEQVKVCREFSKRMGIVNFFEVGQM----------GVEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVPGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[167][TOP]
>UniRef100_C4FRW1 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
17748 RepID=C4FRW1_9FIRM
Length = 419
Score = 105 bits (263), Expect = 2e-21
Identities = 56/162 (34%), Positives = 92/162 (56%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAK-VWDTEK 236
MT+TEK +A+ A V+PG I + D ++ +D+ P ++EF + K V+D K
Sbjct: 3 MTITEKNMARHAGLDVVKPGQIIECHLDAVLMNDITFPPA----RKEFLKIGKPVFDRHK 58
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++PDH+ +D+++ ++RDFV E GI ++++ G+ HV L +
Sbjct: 59 IYLVPDHFTPNKDIQSATQAKVMRDFVREHGITNYFEV----------GRMGIEHVILPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PGE++ G DSHTC GA F+TG+G++DAG M G
Sbjct: 109 KGLIGPGEMMIGADSHTCTYGAVNAFSTGVGSTDAGVAMAEG 150
[168][TOP]
>UniRef100_C4ETQ1 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermanaerovibrio acidaminovorans DSM 6589
RepID=C4ETQ1_9BACT
Length = 420
Score = 105 bits (263), Expect = 2e-21
Identities = 61/162 (37%), Positives = 88/162 (54%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P T EK+L K A R V+ GD + V M+HD P I ++ G ++V+D +
Sbjct: 4 PRTFAEKVLGKWAGR-PVKAGDVVTVEPHFCMSHDNAAP--IARTFKKIGV-SRVFDPNR 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+V I DH + +N +R+FV EQGI +F+D+T + GVCH + +
Sbjct: 60 IVFILDHAVPAPSDDHAQNHKEIREFVREQGIPHFFDVTSKG---------GVCHQKMCE 110
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
EG+ PG ++ G+DSHTC GAFG F+TGIG S+ TG
Sbjct: 111 EGYALPGLIMIGSDSHTCTYGAFGAFSTGIGRSEMAAAWATG 152
[169][TOP]
>UniRef100_B1QZX5 3-isopropylmalate dehydratase, large subunit n=2 Tax=Clostridium
butyricum RepID=B1QZX5_CLOBU
Length = 419
Score = 105 bits (263), Expect = 2e-21
Identities = 58/161 (36%), Positives = 92/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V+ G I + D+++ +D+ P + FK+ FG D KV+ K+
Sbjct: 3 MTMTQKILAAHAGLECVKAGQLIEADLDLVLGNDITTPVAVNEFKK-FGTD-KVFSKSKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A V +R+F N+ I+ F++I + G+ H + ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQVKYIREFANKMEIENFFEIGEM----------GIEHCLVPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLAVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[170][TOP]
>UniRef100_A5UL50 3-isopropylmalate dehydratase, LeuC n=1 Tax=Methanobrevibacter
smithii ATCC 35061 RepID=A5UL50_METS3
Length = 417
Score = 105 bits (263), Expect = 2e-21
Identities = 59/161 (36%), Positives = 86/161 (53%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M +TEKIL+ A++ V PG+ I + D+ M+HD P I F++ KVWD EK+
Sbjct: 1 MNITEKILSAKAKK-EVTPGEIIEIPVDLAMSHDGTSPPAIKTFEKVA---TKVWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH + + + + RDF+ +Q I Y D G+CH L ++
Sbjct: 57 AIVFDHNVPANTIGSAEFQKVCRDFIKKQKITKNYIHGD-----------GICHQVLPEK 105
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA+G F+TG+G +D V TG
Sbjct: 106 GLVEPGKVIVGADSHTCTYGAYGAFSTGMGATDLAMVYATG 146
[171][TOP]
>UniRef100_B9AG62 Putative uncharacterized protein n=1 Tax=Methanobrevibacter smithii
DSM 2375 RepID=B9AG62_METSM
Length = 420
Score = 105 bits (263), Expect = 2e-21
Identities = 59/163 (36%), Positives = 87/163 (53%)
Frame = +3
Query: 54 TPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTE 233
T + +TEKIL+ A++ V PG+ I + D+ M+HD P I F++ KVWD E
Sbjct: 2 TVLNITEKILSAKAKK-EVTPGEIIEIPVDLAMSHDGTSPPAIKTFEKVA---TKVWDNE 57
Query: 234 KVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALA 413
K+ I+ DH + + + + RDF+ +Q I Y D G+CH L
Sbjct: 58 KIAIVFDHNVPANTIGSAEFQKVCRDFIKKQKITKNYIHGD-----------GICHQVLP 106
Query: 414 QEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
++G PG+V+ G DSHTC GA+G F+TG+G +D V TG
Sbjct: 107 EKGLVEPGKVIVGADSHTCTYGAYGAFSTGMGATDLAMVYATG 149
[172][TOP]
>UniRef100_A9IHX4 LeuC1 protein n=1 Tax=Bordetella petrii DSM 12804
RepID=A9IHX4_BORPD
Length = 420
Score = 105 bits (262), Expect = 2e-21
Identities = 57/160 (35%), Positives = 84/160 (52%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL +K+LA A+ R +VR G+ + D+ M HD GP + E G +WD KVV
Sbjct: 5 TLAQKLLAAASGRAAVRVGEILTCKVDLAMFHDSSGPRRLKPMLEELGTG--LWDRSKVV 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DHY+ D + R V I RD+ EQ + + YD G+CHV + + G
Sbjct: 63 LVMDHYVPEADDESRRIVRIARDWAREQALPHVYDSM------------GICHVVVPEHG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
H RPG G DSH+ GAFG + G+G+++ V+ +G
Sbjct: 111 HIRPGMFCVGGDSHSPTGGAFGAYMFGVGSTEMLGVVASG 150
[173][TOP]
>UniRef100_B1C9W1 Putative uncharacterized protein n=1 Tax=Anaerofustis
stercorihominis DSM 17244 RepID=B1C9W1_9FIRM
Length = 424
Score = 105 bits (262), Expect = 2e-21
Identities = 59/161 (36%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A SV+ G I D++M +D+ + FK+ + KV++ EKV
Sbjct: 3 MTMTQKILAKHAGLNSVKAGQLIEAKLDIVMGNDITTAVALKEFKKTGAK--KVFNEEKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH+ +D++A R+F + IK F+D+ G+ H L ++
Sbjct: 61 AIVLDHFTPNKDIKAAEQCKSCRNFAWDMNIKNFFDVGQM----------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGEV+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVVPGEVIIGADSHTCTYGALGAFSTGVGSTDMAIGMATG 151
[174][TOP]
>UniRef100_A6LPX4 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
beijerinckii NCIMB 8052 RepID=LEUC_CLOB8
Length = 419
Score = 105 bits (261), Expect = 3e-21
Identities = 57/161 (35%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A +V+ G I N D+++ +D+ P + FK+ FG D KV+ ++
Sbjct: 3 MTMTQKILAAHAGLEAVKAGQLIEANLDLVLGNDITTPVAVNEFKK-FGTD-KVFSKSQI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A V +R+F I+ F+++ + G+ H L ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQVKYIREFAQNMEIENFFEVGEM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[175][TOP]
>UniRef100_C2KW91 3-isopropylmalate dehydratase n=1 Tax=Oribacterium sinus F0268
RepID=C2KW91_9FIRM
Length = 421
Score = 104 bits (260), Expect = 4e-21
Identities = 56/161 (34%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILAK A V+ G I D++ +D+ P I + GE V+D EKV
Sbjct: 3 MTMSQKILAKHAGLEEVQAGQLILAKVDLVHGNDITTPVAIRELDKIHGEG--VFDKEKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V + DH++ +D+ + + I R+F E G+K++YD+ + G+ H + ++
Sbjct: 61 VFVMDHFVPNKDITSAKCTQICRNFAKEHGLKHYYDVGNM----------GIEHALIPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLITAGELSIGADSHTCTYGALGAFSTGVGSTDMAAAMATG 151
[176][TOP]
>UniRef100_A9BGP4 3-isopropylmalate dehydratase, large subunit n=1 Tax=Petrotoga
mobilis SJ95 RepID=A9BGP4_PETMO
Length = 419
Score = 104 bits (259), Expect = 5e-21
Identities = 54/161 (33%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKILA + + V+PG+ + D+++ +DV P I F R+ G +KV+D E++
Sbjct: 1 MTIVEKILASHSNKSEVKPGEIVNARVDLVLGNDVTTPVAIKEF-RKIGL-SKVFDNERI 58
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ +N ++R+F E I +++I G+ H + ++
Sbjct: 59 AIVPDHFTPNKDIKSAQNALLIRNFAKEMNILNYFEIGKM----------GIEHCLIPEK 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGE++ G DSHTC GA TG+G++D M TG
Sbjct: 109 GLALPGEIVVGADSHTCTYGALNCLGTGVGSTDMAAAMATG 149
[177][TOP]
>UniRef100_A6TSE5 3-isopropylmalate dehydratase n=1 Tax=Alkaliphilus metalliredigens
QYMF RepID=A6TSE5_ALKMQ
Length = 425
Score = 104 bits (259), Expect = 5e-21
Identities = 60/161 (37%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M EK+LA+A+ + V+PG+ I D+ +D+ TI F G KVWD +K+
Sbjct: 1 MHAIEKVLARASGKREVKPGEIIQAKIDLAEVNDLYLQ-TIKSFYEMKG--TKVWDPDKI 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I DHY ++A N +R+F EQGIK+ +D+ + GVCH + +E
Sbjct: 58 TFILDHYAPAPSIQAASNQKEMREFCKEQGIKHLFDVNE-----------GVCHQVMVEE 106
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG +L TDSHT GAFG TG+G +D +M TG
Sbjct: 107 GLVWPGMILVATDSHTTTHGAFGALGTGVGATDLATIMLTG 147
[178][TOP]
>UniRef100_C7MMM0 3-isopropylmalate dehydratase, large subunit n=1
Tax=Cryptobacterium curtum DSM 15641 RepID=C7MMM0_CRYCD
Length = 423
Score = 104 bits (259), Expect = 5e-21
Identities = 56/164 (34%), Positives = 90/164 (54%)
Frame = +3
Query: 51 ATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDT 230
A PMT+ EK+L+ A SV+PG I D+++ +D+ P I F E G V+D
Sbjct: 3 AQPMTMAEKLLSAHAGVDSVQPGQLIDCAVDLVLANDITAPLAIRAF-HELGVK-NVFDP 60
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
+K+ ++PDH +D+ + + ++RDF EQ I ++Y++ G+ H L
Sbjct: 61 QKIALVPDHSTPNKDIASAKLTKMMRDFAYEQEITHYYEV----------GCMGIEHALL 110
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
++G G+++ G DSHTC GA G F+TG+G++D G TG
Sbjct: 111 PEQGVVGAGDLVIGADSHTCTYGALGAFSTGMGSTDVGVAFATG 154
[179][TOP]
>UniRef100_C0V4R3 3-isopropylmalate dehydratase, large subunit n=1 Tax=Veillonella
parvula DSM 2008 RepID=C0V4R3_9FIRM
Length = 419
Score = 104 bits (259), Expect = 5e-21
Identities = 56/162 (34%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAK-VWDTEK 236
MT+TEK +A A V+PG I D ++ +D+ P ++EF + K V+D K
Sbjct: 3 MTITEKNMAHHAGLDVVKPGQIIECQLDAVLMNDITFPPA----RKEFLKIGKPVFDRHK 58
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++PDH+ +D+++ ++RDFV E GI ++++ G+ HV L +
Sbjct: 59 IYLVPDHFTPNKDIQSATQAKVMRDFVREHGITNYFEV----------GRMGIEHVILPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PGE++ G DSHTC GA F+TG+G++DAG M G
Sbjct: 109 KGLIGPGEMMIGADSHTCTYGAVNAFSTGVGSTDAGVAMAEG 150
[180][TOP]
>UniRef100_B6FST2 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FST2_9CLOT
Length = 438
Score = 104 bits (259), Expect = 5e-21
Identities = 58/161 (36%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I DV+M +D+ GP + VF + KV+D +KV
Sbjct: 17 MTMTQKILAAHAGLESVTAGQLIEAKLDVVMANDITGPMAVPVF---YQMADKVFDKDKV 73
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ N +R+F Q + ++++I G+ H L ++
Sbjct: 74 VLVPDHFTPNKDIKSAENSKSIREFSKCQCLTHYFEIGQM----------GIEHAILPEK 123
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 124 GIVVAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMATG 164
[181][TOP]
>UniRef100_A9A5B7 3-isopropylmalate dehydratase n=1 Tax=Nitrosopumilus maritimus SCM1
RepID=A9A5B7_NITMS
Length = 422
Score = 104 bits (259), Expect = 5e-21
Identities = 56/164 (34%), Positives = 86/164 (52%), Gaps = 3/164 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF---KREFGEDAKVWDT 230
M + EKILA+A+ + V P D ++ D +M HDV GPG + VF K + + +K+WD
Sbjct: 1 MNIVEKILARASGKSQVAPDDVVFAKVDKVMVHDVSGPGVLKVFDKLKNKGVDVSKLWDP 60
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
KV + DH++ + + + N+ L +F GI+ +K G+CH
Sbjct: 61 TKVWVAEDHFVPSAEKISAENIVKLSNFTKNYGIE--------KHFKYGMGQYGICHTLS 112
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+E PG+V G DSHT GA G FA G+G++D +V+ G
Sbjct: 113 HEEAMVMPGDVYVGGDSHTNTTGALGAFACGLGHTDIAYVLLNG 156
[182][TOP]
>UniRef100_B4U7U5 3-isopropylmalate dehydratase large subunit n=1
Tax=Hydrogenobaculum sp. Y04AAS1 RepID=LEUC_HYDS0
Length = 424
Score = 103 bits (258), Expect = 6e-21
Identities = 52/160 (32%), Positives = 91/160 (56%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+TEKI+A A + V PG+ + D+ M +DV P +I ++ +G + KV+D +K+
Sbjct: 4 TITEKIIADHAGKKEVFPGELVTAKIDLAMANDVTAPLSIKTLEK-YGIE-KVFDKDKIA 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ H++ +D+++ I+RDF + IK+F+ + +G+ H L + G
Sbjct: 62 LVLSHFVPAKDIKSAEQAKIVRDFAKKHNIKWFFG-----------EGEGIEHTLLPENG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG+++ G DSHTC G G F+TG+G++D + M TG
Sbjct: 111 IVVPGDLVVGADSHTCTYGGIGAFSTGVGSTDLAYAMATG 150
[183][TOP]
>UniRef100_B2AHK6 3-isopropylmalate dehydratase large subunit n=1 Tax=Cupriavidus
taiwanensis RepID=B2AHK6_CUPTR
Length = 428
Score = 103 bits (257), Expect = 8e-21
Identities = 53/164 (32%), Positives = 82/164 (50%)
Frame = +3
Query: 51 ATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDT 230
A P TL +K++A+AA PG + D+ M+HD GP + +E G VWD
Sbjct: 3 AIPATLAQKLVARAAGLAYAEPGSVVICQVDLAMSHDSSGPRRVAPLLQELGTG--VWDP 60
Query: 231 EKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVAL 410
+ V++ DH++ D +A + RD+ E G + D +G+CHV L
Sbjct: 61 SRYVVVTDHFVPGGDAQAESILRFTRDWTREAGAHFI-------------DAEGICHVVL 107
Query: 411 AQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ GH PG ++ G DSH+ GAFG + G+G ++ V+ TG
Sbjct: 108 PEHGHVLPGRLIVGGDSHSPTGGAFGAYMFGVGATEMAGVLATG 151
[184][TOP]
>UniRef100_C7II84 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7II84_9CLOT
Length = 419
Score = 103 bits (257), Expect = 8e-21
Identities = 59/161 (36%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V PG I D+++ +D+ P I F + G D KV+D K+
Sbjct: 3 MTMTQKILANHAGIDKVVPGQLIKAKLDMVLGNDITSPVAIKEFNK-IGLD-KVFDKNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ V + R+F + I F+++ GV H L +
Sbjct: 61 AIVPDHFTPNKDIKSAEQVKLCREFSKKMEIVNFFEVGQM----------GVEHALLPER 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVVPGDVIIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[185][TOP]
>UniRef100_A9WD11 3-isopropylmalate dehydratase n=2 Tax=Chloroflexus
RepID=A9WD11_CHLAA
Length = 418
Score = 103 bits (256), Expect = 1e-20
Identities = 53/160 (33%), Positives = 88/160 (55%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T++E+IL++ A R +VR GD + N D++M HD PG I + +E G + +VWD ++V
Sbjct: 3 TMSEQILSRVAGR-TVRAGDVVTANVDLVMVHDSLAPGIIRILHQELGAE-RVWDPQRVA 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH V+ +R +V QGI + +D+ +G+ H L +EG
Sbjct: 61 VVIDHVAPAASVQTAEKQQEVRRWVRAQGIPHLFDVG-----------RGISHPVLVEEG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+PG ++ G+DSH+ G G F TG+G++D + TG
Sbjct: 110 LAQPGMLILGSDSHSTAYGCVGAFGTGMGSTDIALALATG 149
[186][TOP]
>UniRef100_B3T9D1 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG6J21 RepID=B3T9D1_9ARCH
Length = 423
Score = 103 bits (256), Expect = 1e-20
Identities = 58/165 (35%), Positives = 86/165 (52%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDA----KVWD 227
M +TEKILA+A+ + + PGD I+ N D +M HDV GPG I F++ + K++D
Sbjct: 1 MNITEKILARASGKDMLEPGDVIFANVDKIMLHDVSGPGVIKTFEKLEKDGVVKVDKLFD 60
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
V + DH++ + D + N+ L F + GI +K G+CH
Sbjct: 61 PSMVWVAEDHFVPSVDKISAENIVQLSKFTKKFGIT--------KHFKYGLGQYGICHTL 112
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+EG PGE+ G DSHT GA G FA G+G++D +V+ G
Sbjct: 113 SHEEGLVSPGELYIGGDSHTNTTGALGAFACGLGHTDVAYVLLNG 157
[187][TOP]
>UniRef100_B3T8D2 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG5E24 RepID=B3T8D2_9ARCH
Length = 423
Score = 103 bits (256), Expect = 1e-20
Identities = 58/165 (35%), Positives = 86/165 (52%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDA----KVWD 227
M +TEKILA+A+ + + PGD I+ N D +M HDV GPG I F++ + K++D
Sbjct: 1 MNITEKILARASGKDMLEPGDVIFANVDKIMLHDVSGPGVIKTFEKLEKDGVVKVDKLFD 60
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
V + DH++ + D + N+ L F + GI +K G+CH
Sbjct: 61 PSMVWVAEDHFVPSVDKISAENIVQLSKFTKKFGIT--------KHFKYGLGQYGICHTL 112
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+EG PGE+ G DSHT GA G FA G+G++D +V+ G
Sbjct: 113 SHEEGLVSPGELYIGGDSHTNTTGALGAFACGLGHTDVAYVLLNG 157
[188][TOP]
>UniRef100_C6PJB4 3-isopropylmalate dehydratase, large subunit n=1
Tax=Thermoanaerobacter italicus Ab9 RepID=C6PJB4_9THEO
Length = 418
Score = 102 bits (255), Expect = 1e-20
Identities = 55/161 (34%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
+TLT+KIL+ R V+ G+ I V+ D+++ +DV P I F++ E+ V+D K+
Sbjct: 3 LTLTQKILSAKIGR-EVKAGELIEVDVDMVLGNDVTAPVAIREFEKIGKEE--VFDKTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH++ +D+++ V+I+R F + GI F+++ G+ H L ++
Sbjct: 60 ALVPDHFVPNKDIKSAEQVNIMRKFAKKHGIVNFFEVGQM----------GIEHALLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA F+TG+G++D M TG
Sbjct: 110 GLVLPGDVVIGADSHTCTYGALTCFSTGVGSTDMAAAMATG 150
[189][TOP]
>UniRef100_B3TAM8 Putative aconitase family (Aconitate hydratase) n=1 Tax=uncultured
marine crenarchaeote HF4000_APKG8G2 RepID=B3TAM8_9ARCH
Length = 423
Score = 102 bits (255), Expect = 1e-20
Identities = 58/165 (35%), Positives = 85/165 (51%), Gaps = 4/165 (2%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDA----KVWD 227
M +TEKILA+ A + + PGD I+ N D +M HDV GPG I F++ + K++D
Sbjct: 1 MNITEKILARGAGKDMLEPGDVIFANVDKIMLHDVSGPGVIKTFEKLEKDGVVKVDKLFD 60
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
V + DH++ + D + N+ L F + GI +K G+CH
Sbjct: 61 PSMVWVAEDHFVPSVDKISAENIVQLSKFTKKFGIT--------KHFKYGLGQYGICHTL 112
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+EG PGE+ G DSHT GA G FA G+G++D +V+ G
Sbjct: 113 SHEEGLVSPGELYIGGDSHTNTTGALGAFACGLGHTDVAYVLLNG 157
[190][TOP]
>UniRef100_B0K0Y2 3-isopropylmalate dehydratase large subunit n=4
Tax=Thermoanaerobacter RepID=LEUC_THEPX
Length = 418
Score = 102 bits (255), Expect = 1e-20
Identities = 55/161 (34%), Positives = 93/161 (57%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
+TLT+KIL+ R V+ G+ I V+ D+++ +DV P I F++ E+ V+D K+
Sbjct: 3 LTLTQKILSAKIGR-EVKAGELIEVDVDMVLGNDVTAPVAIKEFEKIGKEE--VFDKTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH++ +D+++ V+I+R F + GI F+++ G+ H L ++
Sbjct: 60 ALVPDHFVPNKDIKSAEQVNIMRKFAKKHGIVNFFEVGQM----------GIEHALLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA F+TG+G++D M TG
Sbjct: 110 GLVLPGDVVIGADSHTCTYGALTCFSTGVGSTDMAAAMATG 150
[191][TOP]
>UniRef100_B9E370 Putative uncharacterized protein n=1 Tax=Clostridium kluyveri NBRC
12016 RepID=B9E370_CLOK1
Length = 426
Score = 102 bits (254), Expect = 2e-20
Identities = 57/165 (34%), Positives = 92/165 (55%)
Frame = +3
Query: 48 IATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWD 227
I MT+T+KILA A SV+ G+ I V D+++ +D+ P I F + G + KV+
Sbjct: 5 IYVAMTMTQKILASHAGLDSVKSGELIKVKLDLVLGNDITTPVAINEFNK-IGSN-KVFH 62
Query: 228 TEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVA 407
EKV I+PDH+ +D+++ +R+F ++ IK +++I G+ H
Sbjct: 63 KEKVAIVPDHFTPNKDIKSAEQCKCVREFAKDKDIKNYFEIGQM----------GIEHAL 112
Query: 408 LAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ ++G G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 113 IPEKGLAVCGDVIIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 157
[192][TOP]
>UniRef100_C3RJS7 Putative uncharacterized protein n=1 Tax=Mollicutes bacterium D7
RepID=C3RJS7_9MOLU
Length = 422
Score = 102 bits (253), Expect = 2e-20
Identities = 57/161 (35%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A +V G I DV+M +D+ GP + +F + KV+D +KV
Sbjct: 1 MTMTQKILAKHAGLDAVVAGQLIEAKLDVVMANDITGPMALPIFHQMAD---KVFDRDKV 57
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
+++PDH+ +D+++ N + DF N+Q + + + GV H L ++
Sbjct: 58 ILVPDHFTPNKDIKSAENSKAILDFSNDQCLTHHME----------QGKCGVEHAILPEK 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 108 GIVVAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMATG 148
[193][TOP]
>UniRef100_B0N943 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
1402 RepID=B0N943_9FIRM
Length = 424
Score = 102 bits (253), Expect = 2e-20
Identities = 57/161 (35%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A +V G I DV+M +D+ GP + +F + KV+D +KV
Sbjct: 3 MTMTQKILAKHAGLDAVVAGQLIEAKLDVVMANDITGPMALPIFHQMAD---KVFDKDKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
+++PDH+ +D+++ N + DF N+Q + + + GV H L ++
Sbjct: 60 ILVPDHFTPNKDIKSAENSKAILDFSNDQCLTHHME----------QGKCGVEHAILPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE + G DSHTC GA G F+TG+G +D M TG
Sbjct: 110 GIVVAGECIIGADSHTCTYGALGAFSTGVGTTDIATGMATG 150
[194][TOP]
>UniRef100_A5MZ75 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
kluyveri DSM 555 RepID=LEUC_CLOK5
Length = 420
Score = 102 bits (253), Expect = 2e-20
Identities = 56/161 (34%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ G+ I V D+++ +D+ P I F + G + KV+ EKV
Sbjct: 3 MTMTQKILASHAGLDSVKSGELIKVKLDLVLGNDITTPVAINEFNK-IGSN-KVFHKEKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ +R+F ++ IK +++I G+ H + ++
Sbjct: 61 AIVPDHFTPNKDIKSAEQCKCVREFAKDKDIKNYFEIGQM----------GIEHALIPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLAVCGDVIIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[195][TOP]
>UniRef100_C1I927 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I927_9CLOT
Length = 424
Score = 101 bits (252), Expect = 3e-20
Identities = 54/161 (33%), Positives = 91/161 (56%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+ G I N D+++ +D+ P + F + + KV++ +K+
Sbjct: 3 MTMTQKILAAHAGLESVKAGQLIEANLDLVLGNDITSPVAVKEFNKLNLD--KVFNKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++A ++R+F E+ I F+++ + G+ H + ++
Sbjct: 61 AIVPDHFTPNKDIKAAEQCKLIREFAREKEITNFFEVGEM----------GIEHCLIPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLAVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[196][TOP]
>UniRef100_B0G7V2 Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC
27755 RepID=B0G7V2_9FIRM
Length = 425
Score = 101 bits (252), Expect = 3e-20
Identities = 56/161 (34%), Positives = 84/161 (52%), Gaps = 2/161 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G I DV+M +D+ GP + + K+ V+D KV
Sbjct: 3 MTMTQKILAAHAGLDHVEAGQLIEAKLDVVMANDITGPMALPILKQM---SDTVFDKNKV 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V +PDH+ +D+++ N +R+F QG+ ++++ GV H L +
Sbjct: 60 VFVPDHFTPNKDIKSAENSKAIREFAKAQGLHWYFE----------QGKSGVEHAILPEA 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G GE++ G DSHTC GA G F+TG+G +D G MG
Sbjct: 110 GVVAAGELIIGADSHTCTYGALGAFSTGVGTTDIATGMAMG 150
[197][TOP]
>UniRef100_Q2FSZ6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Methanospirillum hungatei JF-1 RepID=Q2FSZ6_METHJ
Length = 417
Score = 101 bits (252), Expect = 3e-20
Identities = 59/160 (36%), Positives = 85/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+TEKI + + V G+ + M HD+ GP I F GE KV+D K++
Sbjct: 4 TITEKIFSARCGK-EVTAGEVVMAPISGAMIHDITGPLAIEKFYEMGGE--KVFDPAKII 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH + + + A N +R F EQGI Y YDI + GVCH ++G
Sbjct: 61 MLFDHQVPADSLNAAENQKNMRIFAKEQGI-YNYDIKE-----------GVCHQVTLEKG 108
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG+++ G+DSHTC GA G FATG+G++D GF + G
Sbjct: 109 RVSPGDIVIGSDSHTCMYGAVGAFATGVGSTDMGFALRYG 148
[198][TOP]
>UniRef100_C5EE67 3-isopropylmalate dehydratase large subunit 1 n=1 Tax=Clostridiales
bacterium 1_7_47FAA RepID=C5EE67_9FIRM
Length = 418
Score = 100 bits (250), Expect = 5e-20
Identities = 57/160 (35%), Positives = 87/160 (54%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI+ VRPGD + VN D +M HD+ P F+ E G K+WD ++VV
Sbjct: 4 TIIEKIIKHNTGAAQVRPGDIVTVNVDRVMIHDIFIPFVADKFE-EMGFK-KLWDPDRVV 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DH + + R+ + F G+K+ + RSD G+CH + + G
Sbjct: 62 LIYDHLVPASQLDDTRHFRVGDAFAARYGMKHVH----RSD--------GICHQLMTEAG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ +PG+V+FGTDSHT G G F++GIG ++ ++GTG
Sbjct: 110 YVKPGDVVFGTDSHTTTYGCVGAFSSGIGYTEMASILGTG 149
[199][TOP]
>UniRef100_A9KT79 3-isopropylmalate dehydratase large subunit n=1 Tax=Clostridium
phytofermentans ISDg RepID=LEUC_CLOPH
Length = 421
Score = 100 bits (250), Expect = 5e-20
Identities = 54/161 (33%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V+ G I N D+++ +D+ GP I +R + V+D +K+
Sbjct: 3 MTMTQKILAAHANLPEVKAGQLIEANLDLVLANDITGPVAIHEIQRL--KKKTVFDKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ + +R+F E I +++I + G+ H L ++
Sbjct: 61 ALVPDHFTPNKDIKSAEHCKCVREFAKEHDITNYFEIGEM----------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G GE G DSHTC GA G F+TG+G++D G M TG
Sbjct: 111 GLIVAGETCIGADSHTCTYGALGAFSTGVGSTDMGAGMITG 151
[200][TOP]
>UniRef100_A6TTR7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Alkaliphilus
metalliredigens QYMF RepID=A6TTR7_ALKMQ
Length = 420
Score = 100 bits (249), Expect = 7e-20
Identities = 57/161 (35%), Positives = 94/161 (58%), Gaps = 2/161 (1%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A +V G I V+ D+++ +D+ P + F + G + +V+D +K+
Sbjct: 3 MTMTQKILAAHAGLDTVEVGQLIQVDLDLVLGNDITTPVAMEEFYK-IGVN-QVFDKKKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D++ N ++R+FV+E I+ +++I G+ H + ++
Sbjct: 61 AIVPDHFTPNKDIKTAENCKLIREFVDEMEIENYFEIGQM----------GIEHALIPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G PG+V G DSHTC GA G F+TGIG++D AG MG
Sbjct: 111 GLVVPGDVGIGADSHTCTYGALGAFSTGIGSTDMAAGMAMG 151
[201][TOP]
>UniRef100_Q7VH31 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
hepaticus RepID=LEUC_HELHP
Length = 420
Score = 100 bits (249), Expect = 7e-20
Identities = 55/161 (34%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILA A SVRP D I D+++ +D+ P I FK + KV+D +K+
Sbjct: 3 MTMSQKILADRAGLESVRPNDLIMAKLDMVLGNDITTPVAINAFKE--AKFQKVFDKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D++A R F + I ++YD+ + GV H L ++
Sbjct: 61 SLVMDHFAPNKDIKAATQSAQCRCFAKDFDISHYYDVGNM----------GVEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+++ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVTIGDLIIGADSHTCTYGALGAFSTGVGSTDMAVGMATG 151
[202][TOP]
>UniRef100_B8G9T7 3-isopropylmalate dehydratase n=1 Tax=Chloroflexus aggregans DSM
9485 RepID=B8G9T7_CHLAD
Length = 417
Score = 100 bits (248), Expect = 9e-20
Identities = 52/160 (32%), Positives = 85/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T++E+IL++ A R VR GD + N D++M HD PG I + E G + +VWD +++
Sbjct: 3 TMSEQILSRVAGR-MVRAGDVVTANVDLVMVHDSLAPGIIRILHNELGAE-RVWDPQRIA 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH V+ +R +V QGI +D+ +G+ H L +EG
Sbjct: 61 VVIDHVAPAASVQTAEKQQEVRRWVKAQGIPNLFDVG-----------RGISHPVLVEEG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+PG ++ G+DSH+ G G F TG+G++D + TG
Sbjct: 110 LAQPGMLILGSDSHSTAYGCVGAFGTGMGSTDIALALATG 149
[203][TOP]
>UniRef100_C9LTJ0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Selenomonas
sputigena ATCC 35185 RepID=C9LTJ0_9FIRM
Length = 420
Score = 100 bits (248), Expect = 9e-20
Identities = 57/161 (35%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M +TEKILA+ A V PG I D+++ +D+ P +I F+R V+D EK+
Sbjct: 3 MNMTEKILARHAGLSHVEPGQLITCQLDMVLANDITAPPSIKEFERI---GRPVFDNEKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D++A I+RDF + IK +++I G+ HV L +
Sbjct: 60 ALVPDHFQPAKDIKAAGLGKIVRDFAKKHKIKNYFEI----------GRVGIEHVILPEF 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG + G DSHTC GA F+TG+G +D M TG
Sbjct: 110 GLVGPGMLTIGADSHTCTYGALNGFSTGVGTTDLAVGMATG 150
[204][TOP]
>UniRef100_C8W661 3-isopropylmalate dehydratase, large subunit n=1
Tax=Desulfotomaculum acetoxidans DSM 771
RepID=C8W661_9FIRM
Length = 420
Score = 100 bits (248), Expect = 9e-20
Identities = 54/161 (33%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A + V PG+ + V D+ + +D+ P I F + G D+ V+D EK+
Sbjct: 3 MTVTEKILAAHAGKDKVVPGELVNVKVDLALGNDITAPVAIKEFSK-IGVDS-VFDREKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+I +D+ + +++F + GI F+D+ G+ H L ++
Sbjct: 61 ALVLDHFIPAKDIASAEQGKAVKNFAQKHGIVNFFDVGKM----------GIEHCLLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+++ G DSHTC G G F+TG+G++D M G
Sbjct: 111 GLVGPGDLVIGADSHTCTYGGLGAFSTGVGSTDLAAAMALG 151
[205][TOP]
>UniRef100_C0B4W1 Putative uncharacterized protein n=1 Tax=Coprococcus comes ATCC
27758 RepID=C0B4W1_9FIRM
Length = 417
Score = 100 bits (248), Expect = 9e-20
Identities = 58/161 (36%), Positives = 89/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKI+A AA SV+PGD V D LM++D T+ ++ + ++ + DT+K+
Sbjct: 3 MTIAEKIIAAAAGVESVKPGDIHTVELDRLMSNDGTTHLTVDMYNNKLKKNPHIADTDKL 62
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V I DH + ++ + + +RDF I ++ + KGVCH + E
Sbjct: 63 VFIVDHNVPSDCPKTAASQKKMRDFAKANHIDFW-------------EGKGVCH-QIMME 108
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ RPGE++FG DSHTC+ GA G F TG+G +D + M TG
Sbjct: 109 NYVRPGELIFGADSHTCSYGALGAFGTGVGCTDFLYGMVTG 149
[206][TOP]
>UniRef100_B0PBC0 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
DSM 17241 RepID=B0PBC0_9FIRM
Length = 419
Score = 100 bits (248), Expect = 9e-20
Identities = 56/161 (34%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILAK A V PG I + D+++ +D+ P I ++ E V+ +
Sbjct: 3 MTMSQKILAKKAGLDHVEPGQLINADVDLVLGNDITTPVAIDELEKYGFEH--VFSKTGI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH++ +D++A + RDF + GI +FYD+ G+ H L ++
Sbjct: 61 AIVLDHFVPNKDIKAAQLSKRCRDFAAKHGIVHFYDV----------GRMGIEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PGE++ G DSHTC GA G F+TG G++D VM TG
Sbjct: 111 GLVAPGELIVGADSHTCTYGALGAFSTGFGSTDMAAVMATG 151
[207][TOP]
>UniRef100_A5ZNE1 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
29174 RepID=A5ZNE1_9FIRM
Length = 416
Score = 100 bits (248), Expect = 9e-20
Identities = 60/161 (37%), Positives = 89/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKI+A AA SV+PGD V D LM++D T+ ++K + + DT+K+
Sbjct: 3 MTIAEKIIAAAAGVDSVKPGDIHTVQLDRLMSNDGTTHLTVDMYKNKLNHP-HIADTKKL 61
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V I DH + ++ + + +RDF E I ++ + KGVCH + E
Sbjct: 62 VFIVDHNVPSDCPKTAASQKKMRDFAKENNIDFW-------------EGKGVCHQVMI-E 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ RPGE++FG DSHTC+ GA G F TG+G +D + M TG
Sbjct: 108 NYVRPGELIFGADSHTCSYGALGAFGTGVGCTDFLYGMVTG 148
[208][TOP]
>UniRef100_B1H0A6 3-isopropylmalate dehydratase large subunit n=1 Tax=uncultured
Termite group 1 bacterium phylotype Rs-D17
RepID=LEUC_UNCTG
Length = 420
Score = 100 bits (248), Expect = 9e-20
Identities = 55/160 (34%), Positives = 88/160 (55%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+TEKILA + V PG+ I D+ +++DV P + F++ + KV+D K+
Sbjct: 4 TITEKILASHCGKKVVEPGEFIEPKIDIALSNDVTAPLAVKEFRKTGIK--KVFDKNKIA 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH+ +D+ + +V +R+F E IK++Y+ + GV H L ++G
Sbjct: 62 LVMDHFTPNKDILSAEHVKFVREFAKEHKIKHYYEGGN----------VGVEHALLPEKG 111
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG+V+ G DSHTC GA G F+TG G++D M TG
Sbjct: 112 IVVPGDVIIGADSHTCTYGALGAFSTGGGSTDIAAAMATG 151
[209][TOP]
>UniRef100_A9B805 3-isopropylmalate dehydratase large subunit n=1 Tax=Herpetosiphon
aurantiacus ATCC 23779 RepID=LEUC_HERA2
Length = 421
Score = 100 bits (248), Expect = 9e-20
Identities = 53/160 (33%), Positives = 82/160 (51%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T E+IL A+ R V+ GD + VN D++M HD P I E G + +VWD +KV
Sbjct: 4 TFAEQILGHASGRSDVQAGDMVVVNVDLVMMHDSLSPSIIETLHNELGAE-RVWDRDKVA 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH VR +R +V +QGI + +D+ +G+ H L +EG
Sbjct: 63 VVIDHVAPAATVRQAEQQQQVRRWVAQQGISHLFDVG-----------RGISHPVLIEEG 111
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+PG ++ G+DSH+ GA F +G+G +D + TG
Sbjct: 112 LVQPGMLVVGSDSHSTGYGAAAAFGSGMGTTDIALALATG 151
[210][TOP]
>UniRef100_UPI0001979722 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
cinaedi CCUG 18818 RepID=UPI0001979722
Length = 420
Score = 99.8 bits (247), Expect = 1e-19
Identities = 54/161 (33%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILA A SV+ D I D+++ +D+ P I FK+ + +V+D K+
Sbjct: 3 MTMSQKILADRARLESVKANDLIRAKLDMVLGNDITTPVAINAFKQ--AKFTQVFDKNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D++A R F N+ IK++YD+ + GV H L ++
Sbjct: 61 SLVMDHFAPNKDIKAATQSQQCRCFANDFDIKHYYDVGNM----------GVEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+++ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVTIGDLIIGADSHTCTYGALGAFSTGVGSTDMAVGMATG 151
[211][TOP]
>UniRef100_C6JHQ9 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
5_1_39BFAA RepID=C6JHQ9_9FIRM
Length = 416
Score = 99.8 bits (247), Expect = 1e-19
Identities = 59/161 (36%), Positives = 89/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+ EKI+A AA SV+PGD V D LM++D T+ ++ + ++ + DT K+
Sbjct: 3 MTIAEKIIAAAAGVDSVKPGDIHTVKLDRLMSNDGTTHLTVDMYNNKL-KNPHIADTSKL 61
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V I DH + ++ + + +RDF E I ++ + KGVCH + E
Sbjct: 62 VFIVDHNVPSDSPKTAASQKKMRDFAKEHNIDFW-------------EGKGVCHQVMI-E 107
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ RPGE++FG DSHTC+ GA G F TG+G +D + M TG
Sbjct: 108 NYVRPGELIFGADSHTCSYGALGAFGTGVGCTDFLYGMVTG 148
[212][TOP]
>UniRef100_B0MIU0 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
14662 RepID=B0MIU0_9FIRM
Length = 414
Score = 99.8 bits (247), Expect = 1e-19
Identities = 59/160 (36%), Positives = 88/160 (55%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI+ + SV PG + VN D +M HD+ P F+ E G K+WD +KVV
Sbjct: 4 TIIEKIIKRNTGTESVSPGQIVTVNVDRVMIHDIFIPFVAEKFE-EMGF-TKLWDPDKVV 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DH + V R+ I FV + G+K + RSD G+CH + + G
Sbjct: 62 LIYDHLVPASAVEDIRHFKIGDAFVKKYGLKNIH----RSD--------GICHQLMTECG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ +PG+++FGTDSHT G G F++GIG ++ ++GTG
Sbjct: 110 YAKPGDIVFGTDSHTTTYGCVGCFSSGIGYTEMASILGTG 149
[213][TOP]
>UniRef100_A7IA28 3-isopropylmalate dehydratase large subunit n=1 Tax=Candidatus
Methanoregula boonei 6A8 RepID=LEUC_METB6
Length = 416
Score = 99.8 bits (247), Expect = 1e-19
Identities = 58/160 (36%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI ++ ++ G+ + D M HD+ GP I F G+ +V+D + V+
Sbjct: 4 TIVEKIFSRKCG-SDIKAGEVVMAPIDGAMIHDITGPLAIRKFYEMGGK--QVFDPKSVI 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH I + + A N +R F EQGI + YDI + GVCH + ++G
Sbjct: 61 MLFDHQIPADSLEAAENHVFMRKFAAEQGI-HNYDINE-----------GVCHQVVLEKG 108
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PGE++ G DSHTC GA G FATGIG++D GF + G
Sbjct: 109 RAAPGEIVVGADSHTCMYGAVGAFATGIGSTDMGFALKFG 148
[214][TOP]
>UniRef100_Q0K566 3-Isopropylmalate dehydratase large subunit n=1 Tax=Ralstonia
eutropha H16 RepID=Q0K566_RALEH
Length = 428
Score = 99.4 bits (246), Expect = 1e-19
Identities = 51/163 (31%), Positives = 80/163 (49%)
Frame = +3
Query: 54 TPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTE 233
TP TL +K++A+AA G + D+ M+HD GP + E G VWD
Sbjct: 4 TPATLAQKLVARAAGLAHAEIGTVVICRVDLAMSHDSSGPRRVAPLLEELGTG--VWDPS 61
Query: 234 KVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALA 413
+ V++ DH++ D +A + RD+ + G + D +G+CHV L
Sbjct: 62 RYVVVTDHFVPGGDAQAESILRFTRDWTRQSGAHFI-------------DAEGICHVVLP 108
Query: 414 QEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ GH PG ++ G DSH+ GAFG + G+G ++ V+ TG
Sbjct: 109 ERGHVLPGRLIVGGDSHSPTGGAFGAYMFGVGATEMAGVLATG 151
[215][TOP]
>UniRef100_B9L6Y8 3-isopropylmalate dehydratase large subunit n=1 Tax=Nautilia
profundicola AmH RepID=LEUC_NAUPA
Length = 425
Score = 99.4 bits (246), Expect = 1e-19
Identities = 58/162 (35%), Positives = 87/162 (53%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
PMT+TEKI A+ R V+PG+ I + D+ + +D+ P +I F E K+ +
Sbjct: 2 PMTITEKIFAEHIGR-EVKPGEIIMCDVDMTIGNDITTPISIRAFNESGAE--KLAKPDN 58
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
I+ DH+I +D+ + I RDF + +K F+D D G+ H L +
Sbjct: 59 FAIVLDHFIPPKDIASANQAKINRDFAYKHDLKNFFDEKDM----------GIEHRLLPE 108
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PG+V+ G DSHTC GA G F+TG+G++D F M TG
Sbjct: 109 KGLVIPGDVIIGADSHTCTHGALGAFSTGMGSTDIAFCMITG 150
[216][TOP]
>UniRef100_A7NPM8 Homoaconitate hydratase family protein n=1 Tax=Roseiflexus
castenholzii DSM 13941 RepID=A7NPM8_ROSCS
Length = 419
Score = 99.0 bits (245), Expect = 2e-19
Identities = 54/160 (33%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL E+IL++AA R V G+NI D+ M HD P I + +E G + +VWD ++V
Sbjct: 4 TLAEQILSRAAGR-PVSAGENIVARVDLAMMHDSISPSIIKILHQELGAE-QVWDRDRVA 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH ++ + LR +V +Q I +F+D+ +G+ H L +EG
Sbjct: 62 VVVDHVAPAATIQNAEHQLALRRWVRQQQITHFFDVG-----------RGISHPVLVEEG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
RPG ++ G+DSH+ GA G F G+G++D + TG
Sbjct: 111 LARPGMLILGSDSHSTAYGAVGAFGAGMGSTDMALALATG 150
[217][TOP]
>UniRef100_C6PQI2 3-isopropylmalate dehydratase, large subunit n=1 Tax=Clostridium
carboxidivorans P7 RepID=C6PQI2_9CLOT
Length = 421
Score = 99.0 bits (245), Expect = 2e-19
Identities = 55/161 (34%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV+PG I V D+++ +D+ P I F + + KV+D +K+
Sbjct: 3 MTMTQKILAAHAGVESVKPGQLIKVKLDLVLGNDITTPVAIKEFDKIGVK--KVFDKKKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+PDH+ +D+++ R+F + I+ ++++ G+ H + ++
Sbjct: 61 AIVPDHFTPNKDIKSAEQCKCTREFACKMEIENYFEVGQM----------GIEHALIPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D G M TG
Sbjct: 111 GLAVCGDVIIGADSHTCTYGALGAFSTGIGSTDMGAGMATG 151
[218][TOP]
>UniRef100_C3XG48 3-isopropylmalate dehydratase large subunit n=1 Tax=Helicobacter
bilis ATCC 43879 RepID=C3XG48_9HELI
Length = 420
Score = 99.0 bits (245), Expect = 2e-19
Identities = 54/161 (33%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILA A SV+ D I D+++ +D+ P I FK+ + +V+D K+
Sbjct: 3 MTMSQKILADRAGLESVKANDLIRAKLDMVLGNDITTPVAINAFKQ--AKFTQVFDKNKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+ +D++A R F N+ IK++YD+ + GV H L ++
Sbjct: 61 SLVMDHFAPNKDIKAATQSQQCRCFANDFDIKHYYDVGNM----------GVEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+++ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVTIGDLIIGADSHTCTYGALGAFSTGVGSTDMAVGMATG 151
[219][TOP]
>UniRef100_C0F067 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
3353 RepID=C0F067_9FIRM
Length = 412
Score = 99.0 bits (245), Expect = 2e-19
Identities = 58/160 (36%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL EKI+ K V PG + VN D +M HD+ P F+ E G K+WD +KVV
Sbjct: 4 TLIEKIIEKNTGLSKVTPGQIVTVNVDRVMIHDIFIPFVADKFE-EMGF-TKLWDPDKVV 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DH + T V R+ I F ++ G+ + + R D G+CH + + G
Sbjct: 62 LIYDHLVPTSAVEDVRHFKIGDAFADKYGLTHVH----RRD--------GICHQLMTEAG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ +PG ++FGTDSHT G G F++GIG ++ ++GTG
Sbjct: 110 YAKPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMASILGTG 149
[220][TOP]
>UniRef100_B9W2G9 Isopropyl malate isomerase large subunit 1 (Fragment) n=1
Tax=Arabidopsis thaliana RepID=B9W2G9_ARATH
Length = 60
Score = 98.6 bits (244), Expect = 3e-19
Identities = 44/60 (73%), Positives = 50/60 (83%)
Frame = +3
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
KREFGE AKVWD EK+V+IPDHYIFT D RANRNVDI+R+ EQ IKYFYDITD ++K
Sbjct: 1 KREFGEKAKVWDPEKIVVIPDHYIFTADKRANRNVDIMREHCREQNIKYFYDITDLGNFK 60
[221][TOP]
>UniRef100_A2SR25 3-isopropylmalate dehydratase, large subunit n=1
Tax=Methanocorpusculum labreanum Z RepID=A2SR25_METLZ
Length = 392
Score = 98.6 bits (244), Expect = 3e-19
Identities = 53/134 (39%), Positives = 77/134 (57%)
Frame = +3
Query: 141 DVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVN 320
D M HD+ GP I V K G V+D +KV+++ DH I + + A N ++R F
Sbjct: 5 DGAMIHDITGPLAINVMKEMGG--GSVFDPKKVIMLFDHQIPADSISAAENHVMMRTFAR 62
Query: 321 EQGIKYFYDITDRSDYKANPDYKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFAT 500
EQGI Y YDI + GVCH + ++G +PG+++ G+DSHTC GA G F+T
Sbjct: 63 EQGI-YNYDIKE-----------GVCHQVVPEKGRVKPGDIVVGSDSHTCAYGALGAFST 110
Query: 501 GIGNSDAGFVMGTG 542
GIG++D +V+ G
Sbjct: 111 GIGSTDMAYVLKFG 124
[222][TOP]
>UniRef100_C9KJM7 3-isopropylmalate dehydratase, large subunit n=2 Tax=Mitsuokella
multacida DSM 20544 RepID=C9KJM7_9FIRM
Length = 420
Score = 98.2 bits (243), Expect = 3e-19
Identities = 54/161 (33%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT++EKILAK A SV+ G + D+++ +D+ P +I F+ E G V+D K+
Sbjct: 3 MTMSEKILAKHAGLDSVKAGQLVTCELDMVLANDITAPPSIAKFE-EIGRP--VFDNTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ +RDF ++ I +++ G+ HV L ++
Sbjct: 60 ALVPDHFQPAKDIKSAELAKTVRDFAHKYKIVNYFE----------QGRVGIEHVILPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG + G DSHTC GA F+TG+G++D G M TG
Sbjct: 110 GIVAPGMLTIGADSHTCTYGAVNGFSTGVGSTDLGAAMATG 150
[223][TOP]
>UniRef100_UPI00016C08CB 3-isopropylmalate dehydratase, large subunit n=1 Tax=Epulopiscium
sp. 'N.t. morphotype B' RepID=UPI00016C08CB
Length = 421
Score = 97.8 bits (242), Expect = 4e-19
Identities = 53/161 (32%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V G I + D+++ +D+ P I F + +V+D KV
Sbjct: 3 MTMTQKILAAHAGLEYVEAGQLIEADLDLVLGNDITTPVAITEFNKI--GITEVFDKNKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI+PDH+ +D++A +R+F N++ I ++++ + G+ H + ++
Sbjct: 61 VIVPDHFAPAKDIQAATQCKCVREFANDKNITNYFEVGEM----------GIEHALIPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+ + G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLVVPGDAVIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[224][TOP]
>UniRef100_C4GAI7 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
DSM 14600 RepID=C4GAI7_9FIRM
Length = 434
Score = 97.8 bits (242), Expect = 4e-19
Identities = 54/162 (33%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAK-VWDTEK 236
MT+T+KILA A V G I D+++ +D+ P I V K D K V+D E+
Sbjct: 17 MTMTQKILAAHAGLDHVEVGQLIMAQLDLVLGNDITSPVAIDVMK---DMDTKGVFDRER 73
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++ DH++ +D+++ + +R+F + I +FYD+ G+ H L +
Sbjct: 74 IALVMDHFVPNKDIKSAEHCKCVREFACQHEISHFYDVGQM----------GIEHALLPE 123
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 124 KGLVVAGDVVIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 165
[225][TOP]
>UniRef100_A5US59 Homoaconitase large subunit n=1 Tax=Roseiflexus sp. RS-1
RepID=A5US59_ROSS1
Length = 421
Score = 97.4 bits (241), Expect = 6e-19
Identities = 54/160 (33%), Positives = 84/160 (52%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
TL E+IL+ AA R V G+NI D+ M HD P I + E G + +VWD ++V
Sbjct: 4 TLAEQILSHAAGR-PVSAGENIVARIDLAMMHDSISPSIIKILHHELGAE-RVWDRDRVA 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
++ DH ++ + LR +V +Q I +F+D+ +G+ H L +EG
Sbjct: 62 VVVDHVAPAATIQNAEHQLALRRWVRQQQITHFFDVG-----------RGISHPVLVEEG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
RPG ++ G+DSH+ GA G F G+G++D + TG
Sbjct: 111 LARPGMLIIGSDSHSTAYGAVGAFGAGMGSTDMALALATG 150
[226][TOP]
>UniRef100_C4V4K3 3-isopropylmalate dehydratase n=1 Tax=Selenomonas flueggei ATCC
43531 RepID=C4V4K3_9FIRM
Length = 420
Score = 97.4 bits (241), Expect = 6e-19
Identities = 53/161 (32%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
M ++EKILA+ A V PG + D+++ +DV GP +I F++ V+D K+
Sbjct: 3 MNMSEKILARHAGLDHVEPGQLVVCRLDMVLANDVTGPPSIKEFEKT---GRPVFDRTKI 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
+IPDH+ +D+++ I+RDF ++ I ++Y+ G+ HV L +
Sbjct: 60 ALIPDHFQPAKDIKSAELAKIMRDFAHKHNILHYYE----------QGRVGIEHVILPER 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG + G DSHTC GA F+TG+G +D + TG
Sbjct: 110 GIVGPGMLTIGADSHTCTYGAVNGFSTGVGTTDLAVGIATG 150
[227][TOP]
>UniRef100_C4G1B4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
49176 RepID=C4G1B4_ABIDE
Length = 421
Score = 97.4 bits (241), Expect = 6e-19
Identities = 52/161 (32%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A V+ G+ I V D+++ +DV P I + +D KV+D +K+
Sbjct: 3 MTMTQKILADHAGLEKVQAGELIEVGLDMVLGNDVTAPVAIKELSKF--KDNKVFDKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ N +RD+ I ++++ G+ H L ++
Sbjct: 61 ALVPDHFTPNKDIKSAENCKCMRDYAISNDITNYFEV----------GCMGIEHALLPEQ 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+ + G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GVVTAGDCIIGADSHTCTYGALGAFSTGVGSTDMAAGMVTG 151
[228][TOP]
>UniRef100_A8S7H1 Putative uncharacterized protein n=1 Tax=Faecalibacterium
prausnitzii M21/2 RepID=A8S7H1_9FIRM
Length = 419
Score = 97.1 bits (240), Expect = 7e-19
Identities = 56/161 (34%), Positives = 86/161 (53%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLT+KILA A V+ G I D+++ +D+ P I F+R G D +V+D E +
Sbjct: 3 MTLTQKILAAHAGLPEVKAGQLINAKLDIVLGNDITTPVAINEFERA-GFD-RVFDKEHI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH++ +D+++ R+F N+ I FYD+ G+ H L ++
Sbjct: 61 AIVLDHFVPNKDIKSATQSKQCREFANKYDILNFYDVGQM----------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+ + G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVTAGDCVIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[229][TOP]
>UniRef100_Q46Q52 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ralstonia
eutropha JMP134 RepID=Q46Q52_RALEJ
Length = 434
Score = 96.7 bits (239), Expect = 1e-18
Identities = 50/162 (30%), Positives = 75/162 (46%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P TL +K++A+AA PG D+ M+HD GP + G VWD +
Sbjct: 12 PATLAQKLVARAAGLAHAEPGSLAMCRVDLAMSHDSSGPRRVAPLLEALG--TTVWDPSR 69
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V++ DH++ D A + RD+ G D +G+CHV L +
Sbjct: 70 YVVVTDHFVPASDPAAEAILHFTRDWTRSSGAHLI-------------DGEGICHVVLPE 116
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
GH PG ++ G DSH+ GAFG + G+G ++ V+ TG
Sbjct: 117 HGHVLPGRLIVGGDSHSPTGGAFGAYMFGVGATEMAGVLATG 158
[230][TOP]
>UniRef100_C4Z1K2 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit n=1
Tax=Eubacterium eligens ATCC 27750 RepID=C4Z1K2_EUBE2
Length = 586
Score = 96.7 bits (239), Expect = 1e-18
Identities = 59/173 (34%), Positives = 92/173 (53%)
Frame = +3
Query: 24 ASTAPGVKIATPMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREF 203
++ P + MT+ EKI+A+AA V+ GD V D LM++D TIG++++
Sbjct: 162 STAVPADEAKHGMTIAEKIIARAAGLSQVKAGDIATVTLDRLMSNDGTTHLTIGMYEKL- 220
Query: 204 GEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPD 383
++ + D +K+V I DH I ++ + + +RDF IK++ +
Sbjct: 221 -KNPHIADKDKLVWIVDHNIPSDSPKTAASQKKMRDFAKANDIKFY-------------E 266
Query: 384 YKGVCHVALAQEGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+GVCH + E H PGE++FG DSHTC GA G F TG+G +D + M TG
Sbjct: 267 GEGVCHQVM-MENHVVPGELIFGADSHTCAYGALGAFGTGVGCTDYLYAMVTG 318
[231][TOP]
>UniRef100_C9RAX0 3-isopropylmalate dehydratase, large subunit n=1 Tax=Ammonifex
degensii KC4 RepID=C9RAX0_9THEO
Length = 421
Score = 96.7 bits (239), Expect = 1e-18
Identities = 51/161 (31%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKILA A + V PG+ + DVL+ +D+ P I F+R +++ +
Sbjct: 3 MTITEKILAFHAGKEYVEPGEIVKCRVDVLLANDITAPLAIKEFERL---KVPLFEPNAL 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
V++PDH+ +D+++ +R+F I +++++ G+ H L ++
Sbjct: 60 VLVPDHFTPNKDIKSAEQAKTVREFARRHRIPHYFEV----------GRMGIEHCLLPEQ 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G FATG+G++D M G
Sbjct: 110 GLVVAGDVVIGADSHTCTYGALGAFATGVGSTDLAAAMALG 150
[232][TOP]
>UniRef100_B0MLF2 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
15702 RepID=B0MLF2_9FIRM
Length = 418
Score = 96.7 bits (239), Expect = 1e-18
Identities = 55/162 (33%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVF-KREFGEDAKVWDTEK 236
MT+++KILAK A SVR G I D+++ +D+ P I F K FG +++ +K
Sbjct: 3 MTMSQKILAKHAGLESVREGQLIRAKLDMVLGNDITSPVAINEFNKAGFGG---IFNKDK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++ DH+ +D++A R+F + I +YD+ + G+ H L +
Sbjct: 60 ISLVMDHFTPNKDIKAATQCKQCREFAGKYDITNYYDVGEM----------GIEHALLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+G PGE+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 110 KGLIGPGELCIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[233][TOP]
>UniRef100_B9W2J1 Isopropyl malate isomerase large subunit 1 (Fragment) n=1
Tax=Arabidopsis thaliana RepID=B9W2J1_ARATH
Length = 60
Score = 96.7 bits (239), Expect = 1e-18
Identities = 43/60 (71%), Positives = 49/60 (81%)
Frame = +3
Query: 192 KREFGEDAKVWDTEKVVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYK 371
KREFGE A VWD EK+V+IPDHYIFT D RANRNVDI+R+ EQ IKYFYDITD ++K
Sbjct: 1 KREFGEKANVWDPEKIVVIPDHYIFTADKRANRNVDIMREHCREQNIKYFYDITDLGNFK 60
[234][TOP]
>UniRef100_B0A9M7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
16795 RepID=B0A9M7_9CLOT
Length = 429
Score = 96.3 bits (238), Expect = 1e-18
Identities = 56/161 (34%), Positives = 86/161 (53%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A V+ G I N D+++ +D+ P I F + G D KV+D KV
Sbjct: 3 MTMTQKILAKHAGMNEVKKGQLIEANLDLVLGNDITTPVAITEFNK-LGID-KVFDKTKV 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH+ +D+++ + R F + + ++D+ G+ H L ++
Sbjct: 61 TIVCDHFTPNKDIKSAEQCKVARTFARGKEVINYFDVGQM----------GIEHCLLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TGIG++D M TG
Sbjct: 111 GLVTCGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATG 151
[235][TOP]
>UniRef100_A6Q6J8 3-isopropylmalate dehydratase large subunit n=1 Tax=Sulfurovum sp.
NBC37-1 RepID=LEUC_SULNB
Length = 426
Score = 96.3 bits (238), Expect = 1e-18
Identities = 55/160 (34%), Positives = 88/160 (55%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+TEKI ++ A + V G+ + V+ D+++ +D+ P +I F+ E K+ +
Sbjct: 4 TITEKIFSEHAGK-KVHAGEIVRVDIDMIIGNDITTPISIRAFEESGAE--KLARPDNFS 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
I+ DHYI +D+ + I R+F + +KYF+D D G+ H L ++G
Sbjct: 61 IVMDHYIPAKDIASANQAKISREFAYKHDLKYFFDEKDM----------GIEHALLPEKG 110
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG+V+ G DSHTC GA G F+TG+G++D F M TG
Sbjct: 111 LVIPGDVIIGADSHTCTHGALGAFSTGMGSTDLAFGMITG 150
[236][TOP]
>UniRef100_C7H4B6 3-isopropylmalate dehydratase, large subunit n=1
Tax=Faecalibacterium prausnitzii A2-165
RepID=C7H4B6_9FIRM
Length = 419
Score = 95.9 bits (237), Expect = 2e-18
Identities = 56/161 (34%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTLT+KILA A V+ G I D+++ +D+ P I F++ G D V+D E +
Sbjct: 3 MTLTQKILAAHAGLPEVKAGQLINAKLDIVLGNDITTPVAINEFEKA-GFDG-VFDKEHI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH++ +D+++ R+F N+ I FYD+ GV H L ++
Sbjct: 61 AIVLDHFVPNKDIKSATQSKQCREFANKYDILNFYDVGQM----------GVEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+ + G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GIVTAGDCIIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[237][TOP]
>UniRef100_A5ZAM9 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
ATCC 27560 RepID=A5ZAM9_9FIRM
Length = 421
Score = 95.9 bits (237), Expect = 2e-18
Identities = 56/161 (34%), Positives = 88/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILAK A V+ G I N D+++ +DV P IG K+ D V+ +K+
Sbjct: 3 MTMTQKILAKHAGLDEVKAGQLIEANLDLVLGNDVTAPVAIGEMKK-MNVDC-VFCKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++PDH+ +D+++ ++DF E I +++ T R G+ H L ++
Sbjct: 61 ALVPDHFTPNKDIKSAELYKCVKDFAEENQITNYFE-TGRV---------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLVVAGDVVIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[238][TOP]
>UniRef100_C7P908 3-isopropylmalate dehydratase n=1 Tax=Methanocaldococcus fervens
AG86 RepID=C7P908_METFA
Length = 420
Score = 95.9 bits (237), Expect = 2e-18
Identities = 63/161 (39%), Positives = 83/161 (51%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MTL E+IL+K V GD+I V D+ MTHD P T K E G+ VWD EK+
Sbjct: 1 MTLIEEILSKKVGY-EVCAGDSIEVKVDLAMTHDGTTPLTYKALK-EMGDG--VWDNEKI 56
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
VI DH + V+A ++ +FV IK+F+ +G+CH LA E
Sbjct: 57 VIAFDHNVPANTVKAAEMQKLVLEFVKRFNIKHFHK-----------GGEGICHQILA-E 104
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ P + G DSHTC GAFG FATG G +D ++ TG
Sbjct: 105 NYVLPNMFVAGGDSHTCTHGAFGAFATGFGATDMAYIYATG 145
[239][TOP]
>UniRef100_A6DDD6 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT n=1 Tax=Caminibacter
mediatlanticus TB-2 RepID=A6DDD6_9PROT
Length = 425
Score = 95.5 bits (236), Expect = 2e-18
Identities = 59/161 (36%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+TEKI A R V+PG+ I + D+ + +D+ P +I F RE G K+ +
Sbjct: 3 MTITEKIFADHIGR-EVKPGEIIMCDVDMTIGNDITTPISIKAF-RESGAK-KLAKPDNF 59
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
I+ DH+I +D+ + I R+F E +K F+D D G+ H L ++
Sbjct: 60 AIVLDHFIPPKDIASANQAKINREFAYEHNLKNFFDEKDM----------GIEHRLLPEK 109
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G PG+V+ G DSHTC GA G F+TG+G++D F M TG
Sbjct: 110 GLVIPGDVIIGADSHTCTHGALGAFSTGMGSTDIAFSMITG 150
[240][TOP]
>UniRef100_C4XPA9 3-isopropylmalate dehydratase large subunit n=1 Tax=Desulfovibrio
magneticus RS-1 RepID=C4XPA9_DESMR
Length = 419
Score = 94.7 bits (234), Expect = 4e-18
Identities = 54/162 (33%), Positives = 84/162 (51%), Gaps = 2/162 (1%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P TL EKIL + + PG + +++ +D+ P I FK+ A V+D +K
Sbjct: 2 PATLAEKILQQHCDEQITGPGQIVRCRLSLVLANDITAPLAIKSFKKMGA--AGVFDKDK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V I+ DH+ +D+ + V + R+F E GI ++++ + GV H L +
Sbjct: 60 VTIVADHFTPNKDIESAEQVKVCREFAKEMGITHYFEGGN----------VGVEHALLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G PG+V+ G DSHTC G G FATG+G++D AG +G
Sbjct: 110 LGLVGPGDVVIGADSHTCTYGGLGAFATGMGSTDVAAGMALG 151
[241][TOP]
>UniRef100_C6LJ75 3-isopropylmalate dehydratase, large subunit n=1 Tax=Bryantella
formatexigens DSM 14469 RepID=C6LJ75_9FIRM
Length = 422
Score = 94.7 bits (234), Expect = 4e-18
Identities = 50/161 (31%), Positives = 87/161 (54%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA AA SV G I + D+++ +D+ P + + + + V++ +K+
Sbjct: 3 MTMTQKILAAAAHLPSVEAGQLIEADLDLVLGNDITSP--VAIHEMDKFTKEGVFNKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+I +D+++ + +R F + I ++D+ G+ H L +
Sbjct: 61 ALVMDHFIPNKDIKSAEHCKCVRQFAAKHDITNYFDVGQM----------GIEHALLPES 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G T G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLTVAGDVIIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[242][TOP]
>UniRef100_B6WXT1 Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC
29098 RepID=B6WXT1_9DELT
Length = 420
Score = 94.7 bits (234), Expect = 4e-18
Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 2/162 (1%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P TL +KIL + R G + +++ +D+ GP I FK ++V+D +K
Sbjct: 2 PQTLAQKILQAHTDDVIERDGQIVQCRLSLVLANDITGPLAIKSFKGMGA--SRVFDKDK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
+ ++ DH+ +D+ + V I R F EQGI ++Y+ D GV H L +
Sbjct: 60 IALVMDHFTPQKDIASANQVMISRQFAQEQGITHYYEGGDC----------GVEHTLLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMG 536
G PG+V+ G DSHTC G G FATG+G++D AG +G
Sbjct: 110 RGLVGPGDVVIGADSHTCTYGGIGAFATGMGSTDIAAGMALG 151
[243][TOP]
>UniRef100_UPI000038E0FA 3-isopropylmalate dehydratase large subunit n=1 Tax=Ferroplasma
acidarmanus fer1 RepID=UPI000038E0FA
Length = 413
Score = 94.4 bits (233), Expect = 5e-18
Identities = 55/160 (34%), Positives = 85/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T EKI ++ + S + GD I N D +M +D+ P I F E G K ++K++
Sbjct: 4 TAVEKIFSEKSGTDS-KSGDYIVANVDYVMANDITAPIAIDAFN-ELGMKPK---SDKII 58
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
IIPDH++ +D+ + + +DF E G +FYDI + GVCH + ++G
Sbjct: 59 IIPDHFVPPKDINSAKQYKKSKDFALENGT-WFYDI----------GHGGVCHQVMMEKG 107
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG ++ G DSHT GA +TGIG+++AG + TG
Sbjct: 108 FAAPGRLIAGADSHTNTYGALSAISTGIGSTEAGVIFATG 147
[244][TOP]
>UniRef100_C0D3T2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
DSM 15981 RepID=C0D3T2_9CLOT
Length = 446
Score = 94.4 bits (233), Expect = 5e-18
Identities = 50/161 (31%), Positives = 85/161 (52%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+++KILA A V+ G I + D+++ +D+ P I K+ + V+D +K+
Sbjct: 29 MTMSQKILAAHAGLSEVKAGQLIEADLDLVLGNDITSPVAINEMKKI--DKQTVFDKDKI 86
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH+I +D+++ N R+F I ++D+ D G+ H L ++
Sbjct: 87 ALVMDHFIPNKDIKSAENCKCCREFACRHEITNYFDVGDM----------GIEHALLPEK 136
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G G+ + G DSHTC GA G F+TG+G++D M TG
Sbjct: 137 GLVVAGDAMIGADSHTCTYGALGAFSTGVGSTDMAAAMVTG 177
[245][TOP]
>UniRef100_Q8TLF1 3-isopropylmalate dehydratase large subunit 1 n=1
Tax=Methanosarcina acetivorans RepID=LEUC1_METAC
Length = 424
Score = 94.4 bits (233), Expect = 5e-18
Identities = 53/160 (33%), Positives = 81/160 (50%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T++EKI ++AA + D + + D M HD + FK E KVWD ++V
Sbjct: 14 TISEKIFSRAAGT-EAKANDFVLADVDYAMAHDGTSVLAVNAFKEM--EMEKVWDPSRIV 70
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+ DH + + +R++V EQGI FY++ + G+CH L + G
Sbjct: 71 VPFDHIAPANNETSATLQREIREWVKEQGIPNFYEVGE-----------GICHQVLPENG 119
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
PG+++ G DSH+C GAFG FATG+G +D + TG
Sbjct: 120 FALPGKLVVGADSHSCTYGAFGAFATGVGATDMAEIFATG 159
[246][TOP]
>UniRef100_C6BSG9 3-isopropylmalate dehydratase, large subunit n=1 Tax=Desulfovibrio
salexigens DSM 2638 RepID=C6BSG9_DESAD
Length = 419
Score = 94.0 bits (232), Expect = 6e-18
Identities = 53/162 (32%), Positives = 84/162 (51%)
Frame = +3
Query: 57 PMTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEK 236
P TL EKIL + PG + N +++ +D+ P I F R G D +V+D +K
Sbjct: 2 PKTLAEKILQAHTDETVKEPGQIVRCNVSMVLANDITAPLAIKSF-RAMGAD-QVFDKDK 59
Query: 237 VVIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQ 416
V ++ DH+ +D+ + V ++RDF +E+ I ++Y+ + GV H L +
Sbjct: 60 VALVCDHFTPNKDIDSAEQVKVVRDFAHEKNITHYYEGGE----------VGVEHALLPE 109
Query: 417 EGHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G P +++ G DSHTC G G FATG+G++D M G
Sbjct: 110 LGLVGPSDIVIGADSHTCTYGGLGAFATGMGSTDIAGGMALG 151
[247][TOP]
>UniRef100_C4ETQ3 Homoaconitate hydratase family protein n=1 Tax=Thermanaerovibrio
acidaminovorans DSM 6589 RepID=C4ETQ3_9BACT
Length = 426
Score = 94.0 bits (232), Expect = 6e-18
Identities = 53/161 (32%), Positives = 79/161 (49%), Gaps = 2/161 (1%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T +KI+A+A+ + V+ GD +W D+ D GP + F+ G + KVWD K+
Sbjct: 4 TAIQKIMARASGK-DVQVGDRVWCRIDLSTARDFGGPNCVLQFEEVMGTEGKVWDPNKIA 62
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
D + + N I+R F QGI +D+ G+ L + G
Sbjct: 63 FTFDLQAPAHSEKVSNNQKIIRQFAKRQGISKVFDVN-----------WGIGQHVLLENG 111
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSD--AGFVMGT 539
+PG+V+ GTDSH GA G FATG+GN+D A ++ GT
Sbjct: 112 LVKPGDVILGTDSHMNLLGAVGAFATGVGNTDIVASWIQGT 152
[248][TOP]
>UniRef100_B0NXK3 Putative uncharacterized protein n=1 Tax=Clostridium sp. SS2/1
RepID=B0NXK3_9CLOT
Length = 413
Score = 94.0 bits (232), Expect = 6e-18
Identities = 57/160 (35%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI+++ SV+PG VN D +M HD+ P F+ E G K+WD +KVV
Sbjct: 4 TMIEKIISRNVGVDSVKPGQIQTVNVDRVMIHDIFIPFVAEKFE-EMGF-TKLWDPDKVV 61
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DH + R+ I F + G+K + RSD G+CH + + G
Sbjct: 62 LIYDHMVPASTTDDIRHFKIGDAFAKKYGMKNVH----RSD--------GICHQLMTECG 109
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ +PG ++FGTDSHT G G F++GIG ++ ++GTG
Sbjct: 110 YAKPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMAAILGTG 149
[249][TOP]
>UniRef100_C7GFH7 3-isopropylmalate dehydratase, large subunit n=1 Tax=Roseburia
intestinalis L1-82 RepID=C7GFH7_9FIRM
Length = 420
Score = 93.6 bits (231), Expect = 8e-18
Identities = 49/161 (30%), Positives = 90/161 (55%)
Frame = +3
Query: 60 MTLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKV 239
MT+T+KILA A SV G I + D+++ +D+ P + + + + + V+D +K+
Sbjct: 3 MTMTQKILAAHAGLPSVSAGQLIEADLDLVLGNDITSP--VAIHEMDKMKVDGVFDKDKI 60
Query: 240 VIIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQE 419
++ DH++ +D+++ ++ +R+F I ++D+ + G+ H L ++
Sbjct: 61 ALVLDHFVPNKDIKSAQHCKCVREFACRHDITNYFDVGEM----------GIEHALLPEK 110
Query: 420 GHTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
G T G+V+ G DSHTC GA G F+TG+G++D M TG
Sbjct: 111 GLTVAGDVIIGADSHTCTYGALGAFSTGVGSTDMAAGMATG 151
[250][TOP]
>UniRef100_C6JHQ7 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
5_1_39BFAA RepID=C6JHQ7_9FIRM
Length = 415
Score = 93.6 bits (231), Expect = 8e-18
Identities = 55/160 (34%), Positives = 86/160 (53%)
Frame = +3
Query: 63 TLTEKILAKAAERGSVRPGDNIWVNTDVLMTHDVCGPGTIGVFKREFGEDAKVWDTEKVV 242
T+ EKI+ + +V+PGD + VN D +M HD+ P F+ E G K+WD +K V
Sbjct: 4 TVIEKIIRNNVGK-TVKPGDIVTVNVDRVMIHDIFIPFVAEKFE-EMGF-TKLWDPDKAV 60
Query: 243 IIPDHYIFTEDVRANRNVDILRDFVNEQGIKYFYDITDRSDYKANPDYKGVCHVALAQEG 422
+I DH + + R+ F + G+K + RSD G+CH + + G
Sbjct: 61 LIYDHLVPASQLDDTRHFHAGDAFARKYGMKNVH----RSD--------GICHQLMTEAG 108
Query: 423 HTRPGEVLFGTDSHTCNAGAFGQFATGIGNSDAGFVMGTG 542
+ +PG ++FGTDSHT G G F++GIG ++ ++GTG
Sbjct: 109 YVKPGNIVFGTDSHTTTYGCVGAFSSGIGYTEMASILGTG 148