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[1][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 110 bits (275), Expect = 6e-23
Identities = 69/173 (39%), Positives = 91/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y NK VA +CNH RT+ H QM +L + E A V+ELK L++ KG
Sbjct: 754 EKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKG-- 811
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP L+S AD K PK +++ + L+
Sbjct: 812 --------KPP-------------LKSKNADGK----------PK----RNLNPESLEKK 836
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ D E KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 837 IAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 889
[2][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 108 bits (269), Expect = 3e-22
Identities = 64/173 (36%), Positives = 90/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y NK VA +CNH RT+ H QM +L + E +KEL+ L + NKG
Sbjct: 614 EKVVVYQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEELKGLLKELQEDLTRVNKG-- 671
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP++ + P + + K + K + K+ R +
Sbjct: 672 --------KPPLKNSDGKPKR-------NLNLKRYKGKLLKLIQKLRKWSETRRLSVTKK 716
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ D E KEDL+TVALGTSK NYLDPRITVAWCK ++VP+EKI
Sbjct: 717 IAQTNTKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKI 769
[3][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 107 bits (266), Expect = 6e-22
Identities = 65/173 (37%), Positives = 90/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y + NK VA +CNH RT+ H QM KL + E A +KELK L + KG
Sbjct: 737 EKVVIYQRANKEVAIICNHQRTISKSHGAQMSKLIEKIEELKATLKELKTDLDRAKKG-- 794
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP++ AD K + +++ + ++
Sbjct: 795 --------KPPLK---------------DADGKQK--------------RNLSPENIEKK 817
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ +R+ K+ +M+ KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 818 IASTNQRIEKMELNMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 870
[4][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 105 bits (261), Expect = 2e-21
Identities = 65/172 (37%), Positives = 87/172 (50%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ Y K NK VA +CNH RT+ H Q++KL R E +KELK L + KG
Sbjct: 358 KIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG--- 414
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP+E +D K+ +S+ + + +
Sbjct: 415 -------KPPLE--------------------------GSDGKKI---RSLEPNAWEKKI 438
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ DM KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 439 AQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 490
[5][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 105 bits (261), Expect = 2e-21
Identities = 65/172 (37%), Positives = 87/172 (50%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ Y K NK VA +CNH RT+ H Q++KL R E +KELK L + KG
Sbjct: 240 KIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG--- 296
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP+E +D K+ +S+ + + +
Sbjct: 297 -------KPPLE--------------------------GSDGKKI---RSLEPNAWEKKI 320
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ DM KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 321 AQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 372
[6][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 105 bits (261), Expect = 2e-21
Identities = 65/172 (37%), Positives = 87/172 (50%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ Y K NK VA +CNH RT+ H Q++KL R E +KELK L + KG
Sbjct: 114 KIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG--- 170
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP+E +D K+ +S+ + + +
Sbjct: 171 -------KPPLE--------------------------GSDGKKI---RSLEPNAWEKKI 194
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ DM KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 195 AQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 246
[7][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 105 bits (261), Expect = 2e-21
Identities = 65/172 (37%), Positives = 87/172 (50%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ Y K NK VA +CNH RT+ H Q++KL R E +KELK L + KG
Sbjct: 760 KIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKG--- 816
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP+E +D K+ +S+ + + +
Sbjct: 817 -------KPPLE--------------------------GSDGKKI---RSLEPNAWEKKI 840
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ DM KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 841 AQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 892
[8][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 104 bits (260), Expect = 3e-21
Identities = 62/173 (35%), Positives = 90/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ NK VA +CNH RT+ H QM +L + E + +KELK L + KG
Sbjct: 723 EKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKIEELKSTLKELKTDLDRAKKG-- 780
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP++ AD K + +S+ + ++
Sbjct: 781 --------KPPLK---------------GADGKQK--------------RSLTPEAIEKK 803
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ +++ K+ M+ KEDL+TVALGTSK NYLDPRITVAWCK +EVP++KI
Sbjct: 804 IATTNQKIEKMEMAMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIDKI 856
[9][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 104 bits (259), Expect = 4e-21
Identities = 62/173 (35%), Positives = 93/173 (53%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+A Y + NK VA +CNH R++ H+ QM KL + E + ++ELK L+K KG
Sbjct: 767 EKIAVYQRANKEVAIICNHQRSVSKSHESQMIKLNEKIDELKSQMEELKADLSKAKKG-- 824
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
KP + D++ ++++ A + ++
Sbjct: 825 --------------------KP-----LGYDKEGKQKRNLAP------------EAIEKK 847
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ E ++ K+ D ++KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 848 IAMVEGKIDKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 900
[10][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 103 bits (257), Expect = 7e-21
Identities = 66/173 (38%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y NK VA +CNH RT+ H QM +L + E ++ELK L++ KG
Sbjct: 773 EKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKG-- 830
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP S AD K PK +++ + L+
Sbjct: 831 --------KPP---------------SKGADGK----------PK----RNLNPEALERK 853
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ D E KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 854 MAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 906
[11][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 102 bits (254), Expect = 2e-20
Identities = 61/173 (35%), Positives = 87/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K YN+ NK VA +CNH RT+ H QM +L + E +KE K L + KG
Sbjct: 706 EKFVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKLEELKGTLKEFKTDLDRAKKG-- 763
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP++ AD K + +++ + ++
Sbjct: 764 --------KPPLK---------------DADGKQK--------------RNLTPEAIEKK 786
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ +++ K+ M+ KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 787 IATTNQKIEKMELSMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 839
[12][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 102 bits (253), Expect = 2e-20
Identities = 65/173 (37%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ Y NK VA +CNH R++ H QM +L + E + ELK LA+ KG
Sbjct: 729 EKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKG-- 786
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
KP + +S D K PK K+M + L+
Sbjct: 787 --------------------KPPLKDS---DGK----------PK----KNMTPEVLERK 809
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ DM+ KEDL+TVALGTSK NYLDPRI+VAWCK EVP+EKI
Sbjct: 810 IAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKI 862
[13][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 102 bits (253), Expect = 2e-20
Identities = 61/171 (35%), Positives = 90/171 (52%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
+A Y + NK VA LCNH R++ GH QM++LE + E ++EL+ L + KG
Sbjct: 480 IADYQRANKQVAILCNHQRSVSKGHSAQMERLEGKMQELEEQLEELETDLDRAKKG---- 535
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
PP+ K E K + ++ + L+ +
Sbjct: 536 ------KPPL--------------------KDSEGK---------VKRNQTPEALEKKIA 560
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++++ K+ DM +K+DL+TVALGTSK NY+DPRITVAWCK +EVP+EKI
Sbjct: 561 ATKQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKI 611
[14][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 102 bits (253), Expect = 2e-20
Identities = 65/173 (37%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ Y NK VA +CNH R++ H QM +L + E + ELK LA+ KG
Sbjct: 635 EKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKG-- 692
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
KP + +S D K PK K+M + L+
Sbjct: 693 --------------------KPPLKDS---DGK----------PK----KNMTPEVLERK 715
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ DM+ KEDL+TVALGTSK NYLDPRI+VAWCK EVP+EKI
Sbjct: 716 IAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKI 768
[15][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 101 bits (251), Expect = 3e-20
Identities = 60/173 (34%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+A Y + NK VA +CNH R++ H QM +L + E A ELK L+K KG
Sbjct: 762 EKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEKIDELKAQRDELKADLSKVRKG-- 819
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+++ D+ + ++ A + +
Sbjct: 820 -------------------------KNLGNDKDGKPKRNLAP------------EAFEKK 842
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + E ++ K+ D ++KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 843 ISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 895
[16][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 101 bits (251), Expect = 3e-20
Identities = 60/173 (34%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+A Y + NK VA +CNH R++ H QM +L + E A ELK L+K KG
Sbjct: 762 EKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEKIDELKAQRDELKADLSKVRKG-- 819
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+++ D+ + ++ A + +
Sbjct: 820 -------------------------KNLGNDKDGKPKRNLAP------------EAFEKK 842
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + E ++ K+ D ++KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 843 ISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 895
[17][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 100 bits (249), Expect = 6e-20
Identities = 61/173 (35%), Positives = 89/173 (51%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+A Y + NK VA +CNH R++ H+ QM ++ + E + ++ELK L NK K
Sbjct: 420 EKIAVYQRANKEVAIICNHQRSVSKSHESQMTRMNEKIDELKSQMEELKADL---NKAKK 476
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
G G S KP+ +++ + ++
Sbjct: 477 GKPLGYDSEG----------KPK--------------------------RNLAPEAIQKK 500
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ E ++ K+ D +KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 501 VATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 553
[18][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 100 bits (249), Expect = 6e-20
Identities = 60/171 (35%), Positives = 89/171 (52%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
+A Y + NK VA LCNH R++ GH QM++LE + E ++EL+ L + +G
Sbjct: 350 IADYQRANKEVAILCNHQRSVSKGHSAQMERLELKMQELEEQLEELETDLDRAKRG---- 405
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
PP+ K E K + ++ + L+ +
Sbjct: 406 ------KPPL--------------------KDSEGK---------VKRNQTPEALEKKIA 430
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ K+ DM +K+DL+TVALGTSK NY+DPRITVAWCK +EVP+EKI
Sbjct: 431 STTQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKI 481
[19][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 99.8 bits (247), Expect = 1e-19
Identities = 60/172 (34%), Positives = 89/172 (51%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KVA Y NK VA +CNH R++ H QM +L+ + + +++ELK L++ KG
Sbjct: 756 KVAVYQHANKEVAIICNHQRSVSKSHSTQMMRLDEKINKLKNFIEELKTDLSRAKKG--- 812
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP++ +D K + ++M + ++ +
Sbjct: 813 -------KPPLK---------------GSDGKTK--------------RNMNPEAIEKKI 836
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ D E KEDL+TVALGTSK NYLDPRITVAWCK EVP+EK+
Sbjct: 837 AQTNVKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKM 888
[20][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 99.0 bits (245), Expect = 2e-19
Identities = 62/173 (35%), Positives = 82/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ Y NK VA +CNH R++ H QM KL + E +KELK L + KG
Sbjct: 733 EKIVVYQHANKQVAIICNHQRSVSKSHSAQMTKLNEKIDELQDVLKELKVDLDRARKGKS 792
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
K+ S + PE+LE + A
Sbjct: 793 PTKSSDGKSK-------RSLTPEVLEKKISQTNA-------------------------- 819
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ K+ DM+ K DL+TVALGTSK NYLDPRITVAWCK +EVP+EK+
Sbjct: 820 ------KIEKMQRDMKTKVDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKL 866
[21][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 98.6 bits (244), Expect = 2e-19
Identities = 62/173 (35%), Positives = 90/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y + NK VA +CNH RT+ H Q++KL + E +KEL L + KG
Sbjct: 757 EKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAVKIEELREQIKELNIDLDRAKKG-- 814
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
P+ M +D K RKR ++ + L+
Sbjct: 815 --------RTPL---------------MGSDGK---RKR-----------NLTPEALEKK 837
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + + ++ K+ DM+ KED++TVALGTSK NY+DPRITVAWCK ++VP+EKI
Sbjct: 838 IMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKI 890
[22][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 98.6 bits (244), Expect = 2e-19
Identities = 62/173 (35%), Positives = 90/173 (52%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y + NK VA +CNH RT+ H Q++KL + E +KEL L + KG
Sbjct: 72 EKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAVKIEELREQIKELNIDLDRAKKG-- 129
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
P+ M +D K RKR ++ + L+
Sbjct: 130 --------RTPL---------------MGSDGK---RKR-----------NLTPEALEKK 152
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + + ++ K+ DM+ KED++TVALGTSK NY+DPRITVAWCK ++VP+EKI
Sbjct: 153 IMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKI 205
[23][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 97.4 bits (241), Expect = 5e-19
Identities = 60/173 (34%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+A Y + NK VA +CN R++ H+ QM ++ + E + ++ELK L NK K
Sbjct: 750 EKIAVYQRANKEVAIICNQQRSVSKSHESQMTRMNEKIDELKSQMEELKADL---NKAKK 806
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
G G S KP+ +++ + ++
Sbjct: 807 GKPLGYDSEG----------KPK--------------------------RNLAPEAIQKK 830
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ E ++ K+ D +KEDL+TVALGTSK NYLDPRITVAWCK +EVP+EKI
Sbjct: 831 VATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 883
[24][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 96.7 bits (239), Expect = 9e-19
Identities = 64/173 (36%), Positives = 82/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y NK VA +CNH RT+ H QM +L + E ++ELK L++ KG
Sbjct: 772 EKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKP 831
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK GA P + PE LE A A
Sbjct: 832 PAK-GADGEPKRNLN------PESLERKIAQTNA-------------------------- 858
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ K+ D + KEDL+ VAL TSK +YLDPRITVAWCK +EVP+EKI
Sbjct: 859 ------KIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKI 905
[25][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 95.5 bits (236), Expect = 2e-18
Identities = 60/172 (34%), Positives = 83/172 (48%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV Y NK VA +CNH RT+ H QM +L + E + LK LA+ KG
Sbjct: 705 KVVVYQHANKEVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKG--- 761
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
PP++ AD K +++ + L+ +
Sbjct: 762 -------KPPLK---------------DADGKR---------------RNLTPEALERKI 784
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ ++ K+ D + KEDL+TVALGTSK NYLDPRI+VAWCK EVP+EK+
Sbjct: 785 AQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKV 836
[26][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 95.1 bits (235), Expect = 3e-18
Identities = 63/177 (35%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
++FYN+ N+ VA LCNH R++P H+ M K++ A
Sbjct: 537 ISFYNEANRRVAILCNHQRSIPKQHESSMSKMQ--------------------------A 570
Query: 188 KAGAASSPPVEVTQYMP------VKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQ 349
+A S E+ YM KP ES T D K RK A + M+ +
Sbjct: 571 QAELISEEIAELQAYMKYLESNQTKPFTFESRTVDAKGNPRKAATR-------QGMKLEA 623
Query: 350 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ L+ A +R M +K+D +TVALGTSK NY+DPRITVA+CK EVP+EKI
Sbjct: 624 CQKKLETAMKRSKVHAIKMRIKDDNKTVALGTSKINYMDPRITVAFCKRYEVPIEKI 680
[27][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 94.0 bits (232), Expect = 6e-18
Identities = 60/173 (34%), Positives = 86/173 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ Y NK VA +CNH RT+ H QM +L + E + L+ LA+ KG
Sbjct: 740 EKIVVYQHANKEVAIICNHQRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKG-- 797
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP+E AD K PK +++ + L+
Sbjct: 798 --------KPPLE---------------DADGK----------PK----RNLTPEALERK 820
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++ K+ D E KE L+T+ALGTSK +YLDPRITVAWCK +EVP+EK+
Sbjct: 821 IGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKV 873
[28][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 93.6 bits (231), Expect = 7e-18
Identities = 61/169 (36%), Positives = 82/169 (48%), Gaps = 1/169 (0%)
Frame = +2
Query: 17 YNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKG-GKGAKA 193
Y+ NK VA LCNH R++P H QM+K++ + A + EL+ L KG + KA
Sbjct: 437 YDIANKEVAILCNHQRSVPKTHTNQMEKIQEKLAGMNKELAELEDELRAAQKGKAENKKA 496
Query: 194 GAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRA 373
+P + LP L S + +
Sbjct: 497 NKCGAPTI------------------------------LPWA----------LNSKIDKK 516
Query: 374 EERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ +AK+ KEDL+TVALGTSK NY+DPRITVAWCK NEVP+EKI
Sbjct: 517 KQAIAKVELQARSKEDLKTVALGTSKINYMDPRITVAWCKRNEVPIEKI 565
[29][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 93.2 bits (230), Expect = 1e-17
Identities = 61/173 (35%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV Y + NK VA +CNH RT+ H QM +L + E ++ELK L++ K GK
Sbjct: 772 EKVGVYQRANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKK-GK 830
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
G P + PE LE A A
Sbjct: 831 PPSKGDDGEPK------RNLNPEALERKIAQTNA-------------------------- 858
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ K+ D + KEDL+ VAL TSK +YLDPRITVAWCK EVP+EK+
Sbjct: 859 ------KIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKM 905
[30][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 92.0 bits (227), Expect = 2e-17
Identities = 61/171 (35%), Positives = 87/171 (50%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 786 VQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKPPSKR 845
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
K V+ Q P K + + M D A+ +L++ LK
Sbjct: 846 KERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQALLK 885
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R + L K+ ++K+D +TVALGTSK NY+DPRITVA+CK EVP+EK+
Sbjct: 886 RRADHLLKI----KLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKL 932
[31][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 92.0 bits (227), Expect = 2e-17
Identities = 61/171 (35%), Positives = 87/171 (50%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 786 VQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKPPSKR 845
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
K V+ Q P K + + M D A+ +L++ LK
Sbjct: 846 KERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQALLK 885
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R + L K+ ++K+D +TVALGTSK NY+DPRITVA+CK EVP+EK+
Sbjct: 886 RRADHLLKI----KLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKL 932
[32][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 92.0 bits (227), Expect = 2e-17
Identities = 61/171 (35%), Positives = 87/171 (50%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
V FYN N+ VA LCNH R++P H MQK+E ++ ++E + L K
Sbjct: 786 VQFYNDANRAVAILCNHQRSVPKQHAASMQKMEHQQLMLDEDIRECEEYLEFLKKPPSKR 845
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
K V+ Q P K + + M D A+ +L++ LK
Sbjct: 846 KERFTFVSDVKDFQGNPRKTNVRDGMKEDVCAR--------------------RLQALLK 885
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R + L K+ ++K+D +TVALGTSK NY+DPRITVA+CK EVP+EK+
Sbjct: 886 RRADHLLKI----KLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKL 932
[33][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 90.5 bits (223), Expect = 6e-17
Identities = 65/215 (30%), Positives = 102/215 (47%), Gaps = 42/215 (19%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAKWNKGG 178
+K+ YN N+ VA LCNH RT+ GH +QK T R E + W K KR + + +K
Sbjct: 556 EKILRYNAANRTVAILCNHQRTVTKGHASSVQKA-TERIEELEWQKVRYKRAILQLDKSE 614
Query: 179 K----------------------------------------GAKAGAASSPPVEVTQYMP 238
+ K + P+ +Q +
Sbjct: 615 RKKNQNYFKEIDDLTKEEELTIHKRIIEREREKYKRKFERENEKRKFSKEDPIPDSQLL- 673
Query: 239 VKPEILESMTADEKAQERKRAADLPKVPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMK 415
E L + EK ER+ K+ L +S++ ++LK N+++ E+R+ + ++ K
Sbjct: 674 ---EWLAKVDDLEKLYERESTTG--KIELRESLQNLEKLKQNVEKLEKRITNCSLQLKDK 728
Query: 416 EDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
ED TVALGTSK NY+DPR++VA+CK +VP+EK+
Sbjct: 729 EDNSTVALGTSKINYIDPRLSVAFCKKFDVPIEKV 763
[34][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 90.1 bits (222), Expect = 8e-17
Identities = 55/173 (31%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + ++E++R + +
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEKIDQKREQIEEMQRQV---KDAAR 165
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ + E + D+K K +
Sbjct: 166 DAKHGS-----------------VKEKLVHDKK------------------------KKS 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L R +E+L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LDRLKEQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[35][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 90.1 bits (222), Expect = 8e-17
Identities = 58/173 (33%), Positives = 85/173 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R +P GH+ M+K++ + +K+ +R + K
Sbjct: 109 EKILSYNRANRAVAILCNHQRAVPKGHEKSMEKIKEKIDAKRQAIKDAERQV-------K 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E T Y E+KR
Sbjct: 162 DAQRDAKHGSVKEKTVY------------------EKKRKL------------------- 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +T+ALGTSK NYLDPRI+VAWCK N+VP+EKI
Sbjct: 185 LERLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKI 237
[36][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 89.4 bits (220), Expect = 1e-16
Identities = 58/173 (33%), Positives = 84/173 (48%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + +K+ +R + K
Sbjct: 786 EKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLKEKIDAKKEAIKDAERQV---KDAAK 842
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ E T Y D+ K
Sbjct: 843 DAKHGSVK----EKTVY-------------------------------------DKKKKM 861
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +T+ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 862 LQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKI 914
[37][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 89.4 bits (220), Expect = 1e-16
Identities = 57/169 (33%), Positives = 84/169 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KVA YN NK VA +CNH R++ H Q+ KL + E A ++E K LA+ KG
Sbjct: 723 EKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNEKIDELKALLEEFKVDLARAKKG-- 780
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
PP++ AD KA+ +++ + L+
Sbjct: 781 --------KPPLK---------------GADGKAK--------------RNLAPEALQKK 803
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVP 508
+ + ++ + +E KE+L+TVALGTSK NYLDPRITVAWC+ + P
Sbjct: 804 IDQTNVKIENIEKQIETKEELKTVALGTSKINYLDPRITVAWCERHRFP 852
[38][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 89.0 bits (219), Expect = 2e-16
Identities = 59/171 (34%), Positives = 81/171 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH RT P + M L+ + ++ VKE K+ L K
Sbjct: 352 KILSYNRANRAVAILCNHQRTAPKTFEKSMSNLQLKISDKKKTVKEAKKELKALRVKAKE 411
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
+K+ ++ KA E+K+A +
Sbjct: 412 SKS------------------------ESNNKAVEKKKA-------------------QV 428
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+R EE+L KL KE+ + +ALGTSK NYLDPRITVAWCK EVP+EK
Sbjct: 429 QRLEEQLFKLEVTATDKEENKEIALGTSKLNYLDPRITVAWCKKFEVPIEK 479
[39][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 88.6 bits (218), Expect = 2e-16
Identities = 60/173 (34%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R +P H+ M L+ + A VKE K
Sbjct: 597 EKILQYNRANRAVAILCNHQRAIPKTHEKSMGNLKEKIQTKRAAVKEAKE---------- 646
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
QY K ++ + + K Q KR K
Sbjct: 647 ---------------QYKQAKRDVKDG-SVHSKTQLEKR------------------KKA 672
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL KE+ +T+ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 673 LERLKEQLTKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKFNVPIEKI 725
[40][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 88.2 bits (217), Expect = 3e-16
Identities = 61/182 (33%), Positives = 98/182 (53%), Gaps = 9/182 (4%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ FYN+ N+ VA LCNH + P M K++ + E + +++L R K GK
Sbjct: 703 EKILFYNRCNREVAILCNHQKAPPKNLAETMSKIDEKIQE-LRDLQDLCR-----IKIGK 756
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRA---------ADLPKVPLLKS 334
K+ E + P++++ ++K +++++ A K L
Sbjct: 757 TPKSQQEDIESREAERL----PKLIQLAITNKKDKDKEKTDKEISFDVKAAFEKSRTLPD 812
Query: 335 MRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVE 514
+G ++K + + EE++ K K++L+TVALGTSK NYLDPRITVAWCK N+VPV+
Sbjct: 813 AKG-KIKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPVD 871
Query: 515 KI 520
KI
Sbjct: 872 KI 873
[41][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 87.8 bits (216), Expect = 4e-16
Identities = 56/164 (34%), Positives = 80/164 (48%)
Frame = +2
Query: 29 NKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 208
+++VA +CNH RT+ H QM +L + E + LK LA+ KG
Sbjct: 1302 DEMVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKG----------K 1351
Query: 209 PPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLA 388
PP+ K + KR P+ +L+ + + ++
Sbjct: 1352 PPL--------------------KDADGKRRNLTPEATY-------RLERKIAQTNAKIE 1384
Query: 389 KLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K+ D + KEDL+TVALGTSK NYLDPRI+VAWCK EVP+EK+
Sbjct: 1385 KMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKV 1428
[42][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 87.4 bits (215), Expect = 5e-16
Identities = 59/176 (33%), Positives = 90/176 (51%), Gaps = 3/176 (1%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH R++ + Q++ + + V +K+ K+ L K
Sbjct: 433 EKVVEYNNANREVAILCNHQRSVSKAQETQLENITAK----VGMLKKQKKDLKK------ 482
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKS---MRGDQL 352
IL+ +TA E AD K+P KS M +Q+
Sbjct: 483 -----------------------ILKLLTAGE--------AD--KIPTKKSPQTMTDEQV 509
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ +++K+ D++ K+D + V+LGTSK NY+DPRI+VAWCK NEVP+EKI
Sbjct: 510 VKKIEAWNGKISKMEMDLKHKDDNKEVSLGTSKINYMDPRISVAWCKRNEVPIEKI 565
[43][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 87.4 bits (215), Expect = 5e-16
Identities = 58/177 (32%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE----TRRAEAVAWVKELKRGLAKWN 169
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ T+R + K++K
Sbjct: 91 EKMLSYNRANRAVAVLCNHQRSVPKGHEKSMEKLKEKIGTKRDQIAEMEKQVK------- 143
Query: 170 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQ 349
K AK G+ + E + D+K
Sbjct: 144 DAQKDAKRGS-----------------VKEKVVYDKK----------------------- 163
Query: 350 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K +L+R E+L KL +++ +++ALGTSK NYLDPRITVAWCK VP+EK+
Sbjct: 164 -KKHLERLREQLVKLEVAETDRDENKSIALGTSKLNYLDPRITVAWCKKYGVPIEKV 219
[44][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 86.7 bits (213), Expect = 9e-16
Identities = 58/174 (33%), Positives = 89/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR-RAEAVAWVKELKRGLAKWNKGG 178
+K+ YN+ N+ VA LCNH R++P GH+ M+ L+ + RA+ A L ++++
Sbjct: 893 EKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----LDECESEYHDLR 948
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K AK G+ + E + AD+K ++
Sbjct: 949 KAAKRGS-----------------VKEKLNADKKGKQ----------------------- 968
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 969 -LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKKYGVPIEKI 1021
[45][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 86.7 bits (213), Expect = 9e-16
Identities = 54/173 (31%), Positives = 85/173 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH M+KL+ + + + E++R
Sbjct: 143 EKILSYNRANRAVAILCNHQRSVPKGHAKSMEKLKEKIEQKKDTISEMER---------- 192
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ Q+ +RAA V + + D+ K
Sbjct: 193 --------------------------------QVQDAQRAAKRGSVK--EKVVYDKKKKA 218
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +++L KL K++ +++ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 219 LEKLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKKYGVPIEKI 271
[46][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 86.7 bits (213), Expect = 9e-16
Identities = 60/192 (31%), Positives = 95/192 (49%), Gaps = 19/192 (9%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVA----------------- 130
+K+ YNK N++VA LCNH R P H M+K+ + A V
Sbjct: 652 EKINAYNKANRMVAILCNHQRAAPKTHDQSMEKMRYKAAPVVEMKKNKKYTQEESDIDDD 711
Query: 131 WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL-ESMTADEKAQER-KRAA 304
W+++ + L K + K K + +E K +L E + A E+ ER +
Sbjct: 712 WIEKHEESL-KEKEIEKAEKKFEKENEKLEAEGKDKQKKSVLKERIEAIEEEFERLAQER 770
Query: 305 DLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVA 484
K L + ++L+ +++ ++R+ M +++ + VALGTSK NYLDPRITVA
Sbjct: 771 GTGKATLKRERPTEKLEEMIEKLDDRIKTFKLQMIDRDEGKEVALGTSKINYLDPRITVA 830
Query: 485 WCKANEVPVEKI 520
W AN+VP+EK+
Sbjct: 831 WASANKVPIEKM 842
[47][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 86.3 bits (212), Expect = 1e-15
Identities = 57/174 (32%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR-RAEAVAWVKELKRGLAKWNKGG 178
+K+ YN+ N+ VA LCNH R++P GH+ M+ L+ + RA+ A + ++++
Sbjct: 904 EKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----IDDCESEYHDLK 959
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K AK G+ + E + AD+K ++
Sbjct: 960 KAAKRGS-----------------VKEKVNADKKGKQ----------------------- 979
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK N VP+EKI
Sbjct: 980 -LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNGVPIEKI 1032
[48][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 86.3 bits (212), Expect = 1e-15
Identities = 57/174 (32%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR-RAEAVAWVKELKRGLAKWNKGG 178
+K+ YN+ N+ VA LCNH R++P GH+ M+ L+ + RA+ A + ++++
Sbjct: 892 EKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----IDDCESEYHDLK 947
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K AK G+ + E + AD+K ++
Sbjct: 948 KAAKRGS-----------------VKEKVNADKKGKQ----------------------- 967
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK N VP+EKI
Sbjct: 968 -LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNGVPIEKI 1020
[49][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 85.9 bits (211), Expect = 2e-15
Identities = 61/172 (35%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E KR L KG
Sbjct: 608 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLVEAKREL-------KG 660
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK ++ A K L
Sbjct: 661 AKADA--------------------KVRKDEKFKKAVEAK----------------KKAL 684
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 685 QRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 736
[50][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 85.9 bits (211), Expect = 2e-15
Identities = 54/173 (31%), Positives = 86/173 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + + +++R + K
Sbjct: 143 EKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEKIDQKKENITDMQRQV---KDAQK 199
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ + E + D+K K
Sbjct: 200 DAKHGS-----------------VKEKVVYDKK------------------------KKA 218
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R ++L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 219 LERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 271
[51][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 85.5 bits (210), Expect = 2e-15
Identities = 55/173 (31%), Positives = 87/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M L+ + + + + A+++ K
Sbjct: 913 EKLLAYNRANRAVAILCNHQRSVPKGHQKSMDNLKEKIRAKRDNIDDCE---AEYHDLKK 969
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ + E + AD+KA++
Sbjct: 970 AAKRGS-----------------VKEKVNADKKAKQ------------------------ 988
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+AL TSK NYLDPRI+VAWCK N VP+EKI
Sbjct: 989 LERLKDQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKKNGVPIEKI 1041
[52][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 85.5 bits (210), Expect = 2e-15
Identities = 53/173 (30%), Positives = 83/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH M+KL+ + +++ K ++ + K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKGHAKSMEKLKEK-------IEQKKDAISDAEQQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKRGSVKEKVVY-------------------------------------DKKKKT 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[53][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 85.1 bits (209), Expect = 3e-15
Identities = 56/176 (31%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVKELKRGLAKWNK 172
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ + + EA+A +++ + + K
Sbjct: 869 EKILSYNRANRAVAILCNHQRSVPKSHEKSMENLKAKIDAKREAIAEAEQIVKDAKRDAK 928
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G VK ++L E+K
Sbjct: 929 HGS-------------------VKEKVL---------YEKK------------------- 941
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K L R +E+L KL +E+ + +ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 942 KKQLDRLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHDVPIEKI 997
[54][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 85.1 bits (209), Expect = 3e-15
Identities = 57/174 (32%), Positives = 89/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR-RAEAVAWVKELKRGLAKWNKGG 178
+K+ YN+ N+ VA LCNH R++P GH+ M+ L+ + RA+ A + ++++
Sbjct: 847 EKLLAYNRANRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----IDDCESEYHDLK 902
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K AK G+ + E + AD+K ++
Sbjct: 903 KAAKRGS-----------------VKEKVNADKKGKQ----------------------- 922
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +T+AL TSK NYLDPRI+VAWCK N VP+EKI
Sbjct: 923 -LERLKEQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKKNGVPIEKI 975
[55][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 85.1 bits (209), Expect = 3e-15
Identities = 51/172 (29%), Positives = 87/172 (50%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV FY+ NK VA LCNH +T+ + +K+ T+ +++EL++ K N
Sbjct: 433 KVDFYDNANKQVAILCNHQKTISKQFELTKKKINTKLECMKTYIQELEQHYKKKN----- 487
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
P E E+ ++K + + K P + D++K +
Sbjct: 488 --------------------PNEYEEEVQLEEGSQKKNSIFIKKFP----GQHDKIKQTI 523
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ +E+ K +E KE+ + +ALGTSK NY DPRI+VA+CK ++VP+E++
Sbjct: 524 QKTQEKYQKELKGLEKKEENKEIALGTSKTNYNDPRISVAFCKVHDVPIERV 575
[56][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
RepID=B3L6G4_PLAKH
Length = 924
Score = 84.7 bits (208), Expect = 3e-15
Identities = 55/171 (32%), Positives = 85/171 (49%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
+ F+N N+ VA LCNH R++P H M K++ + +KE K+ L KG K
Sbjct: 759 INFFNNANREVAILCNHQRSVPKQHDTAMSKIKKQIEIYSEDIKEYKKYLQYLKKGTK-- 816
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
E + K L+ K +E +M+ + K L
Sbjct: 817 ----------EESFTFVSKVVALDGSLRPNKVKE--------------NMKEESCKKKLI 852
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ +L M++++D +T+ALGTSK NY+DPRITVA+CK E+P+EKI
Sbjct: 853 ALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRFEIPIEKI 903
[57][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 84.7 bits (208), Expect = 3e-15
Identities = 51/170 (30%), Positives = 86/170 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + +++E+++ + K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEKIEQKREFIQEMQKXV---KDAAK 165
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ VK +++ D+ K
Sbjct: 166 DAKHGS-------------VKEKVVH----------------------------DKKKKA 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPV 511
L+R ++L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+
Sbjct: 185 LERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234
[58][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 84.3 bits (207), Expect = 4e-15
Identities = 60/172 (34%), Positives = 83/172 (48%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K KG
Sbjct: 620 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKG 672
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 673 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 696
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 697 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 748
[59][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment) n=1
Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 84.3 bits (207), Expect = 4e-15
Identities = 60/172 (34%), Positives = 83/172 (48%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K KG
Sbjct: 633 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKG 685
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 686 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 709
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 710 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 761
[60][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 84.3 bits (207), Expect = 4e-15
Identities = 53/170 (31%), Positives = 85/170 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + + + + + K K
Sbjct: 143 EKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLKEK-------IDQKREQITEMQKQVK 195
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A Q+ VK +++ D+ K
Sbjct: 196 DAQRDA---------QHGSVKEKVVL----------------------------DKKKKG 218
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPV 511
L+R +++L KL K++ +++ALGTSK NYLDPRI+VAWCK EVP+
Sbjct: 219 LERLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKKYEVPI 268
[61][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 84.0 bits (206), Expect = 6e-15
Identities = 53/173 (30%), Positives = 82/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIEEAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[62][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 84.0 bits (206), Expect = 6e-15
Identities = 61/176 (34%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 353 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 412
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 413 QGDGKSRSVL----------------------------EKKRRL---------------- 428
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 429 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 481
[63][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 84.0 bits (206), Expect = 6e-15
Identities = 61/176 (34%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 451 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 510
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 511 QGDGKSRSVL----------------------------EKKRRL---------------- 526
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 527 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 579
[64][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 84.0 bits (206), Expect = 6e-15
Identities = 61/176 (34%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 451 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 510
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 511 QGDGKSRSVL----------------------------EKKRRL---------------- 526
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 527 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 579
[65][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 83.6 bits (205), Expect = 8e-15
Identities = 56/173 (32%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ + E KR
Sbjct: 817 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKAKI--------EAKR---------- 858
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
Q +K E+ + + E K+ K
Sbjct: 859 --------------EQINEIKKEVKNAKRNGDSGTEAKK------------------KKQ 886
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L R +E+L KL KE+ +T+ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 887 LDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKI 939
[66][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 83.6 bits (205), Expect = 8e-15
Identities = 45/80 (56%), Positives = 58/80 (72%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 EKAQERKRAADLPKVPLLKSMRGDQLK--SNLKRAEERLAKLTSDMEMKEDLQTVALGTS 448
EK ++K+A + LK++R D+ K S + +ERLAKL M+MKEDL+TV+LGTS
Sbjct: 585 EKLVDKKKAMEKE----LKALRQDKEKNKSKISTMKERLAKLELQMKMKEDLKTVSLGTS 640
Query: 449 KQNYLDPRITVAWCKANEVP 508
K NYLDPRIT+AWCK NEVP
Sbjct: 641 KINYLDPRITIAWCKRNEVP 660
[67][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 83.6 bits (205), Expect = 8e-15
Identities = 53/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQITDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[68][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 83.6 bits (205), Expect = 8e-15
Identities = 53/173 (30%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIVDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLVKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[69][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 83.6 bits (205), Expect = 8e-15
Identities = 52/170 (30%), Positives = 86/170 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + +++ K +A+ K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEK-------IEQKKEHIAEMQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A A ++ VK +++ D+ K
Sbjct: 162 DAAKDA---------KHGSVKEKVVH----------------------------DKKKKA 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPV 511
L+R +++L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+
Sbjct: 185 LERLKDQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234
[70][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 83.2 bits (204), Expect = 1e-14
Identities = 58/174 (33%), Positives = 88/174 (50%), Gaps = 1/174 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR-RAEAVAWVKELKRGLAKWNKGG 178
+K+ YN+ N+ VA LCNH R++P GH+ M+ L+ + RA+ A + A+++
Sbjct: 895 EKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLKEKIRAKRDA----IDDCEAEYHDLK 950
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K AK G+ + E + AD+K +
Sbjct: 951 KAAKRGS-----------------VKERVIADKKGK------------------------ 969
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 970 ILERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKKYGVPIEKI 1023
[71][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIDEAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[72][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIEDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[73][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/173 (30%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIVDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[74][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/173 (30%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQITDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[75][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/173 (30%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQITDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[76][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax RepID=A5KB33_PLAVI
Length = 931
Score = 83.2 bits (204), Expect = 1e-14
Identities = 54/171 (31%), Positives = 84/171 (49%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
+ F+N N+ VA LCNH R++P H M K++ + +KE K+ L KG
Sbjct: 766 INFFNNANREVAILCNHQRSVPKQHDSAMSKIKKQIEIYSEDIKEYKKYLQYLKKGMN-- 823
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
E + K L+ K +E +M+ + K L
Sbjct: 824 ----------EQSFTFVSKVVALDGSLRPNKVKE--------------NMKEESCKKKLI 859
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ +L M++++D +T+ALGTSK NY+DPRITVA+CK E+P+EKI
Sbjct: 860 ALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRFEIPIEKI 910
[77][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 83.2 bits (204), Expect = 1e-14
Identities = 61/176 (34%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 353 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 412
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 413 QGDGKSRSVL----------------------------EKKRWL---------------- 428
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 429 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 481
[78][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 83.2 bits (204), Expect = 1e-14
Identities = 61/176 (34%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 353 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 412
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 413 QGDGKSRSVL----------------------------EKKRWL---------------- 428
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 429 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 481
[79][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 82.8 bits (203), Expect = 1e-14
Identities = 59/173 (34%), Positives = 83/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R P + MQ L+T+ + E K+ L+ K K
Sbjct: 597 EKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQTK-------IDEKKKQLSAAKKEHK 649
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AKA A + DEK+ K+A + K
Sbjct: 650 AAKADAKA--------------------LHDEKS---KKAVETKK-------------KA 673
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++R E+L KL +E+ + +ALGTSK NYLDPRI+V+WCK VP+EKI
Sbjct: 674 VQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKI 726
[80][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 82.8 bits (203), Expect = 1e-14
Identities = 56/173 (32%), Positives = 86/173 (49%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+ L + + +L+ A++N
Sbjct: 476 EKLLVYNRANRAVAILCNHQRSIPKGHQQIMENLRKKIHNKSNAINDLE---AEFN---- 528
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
E+ S T A+++K A +G QL+
Sbjct: 529 ----------------------ELKRSATLSGTAKDKKIA----------ECKGKQLE-- 554
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R +++L KL + +E+ + VAL TSK NY+DPRI+VAWCK N VP+EKI
Sbjct: 555 --RLKDQLKKLKLEETNREENKCVALTTSKLNYIDPRISVAWCKKNNVPIEKI 605
[81][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 82.8 bits (203), Expect = 1e-14
Identities = 53/173 (30%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQITDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKT 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLMKLEVMETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[82][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 82.4 bits (202), Expect = 2e-14
Identities = 57/172 (33%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 598 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKS 650
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++L+ + + +K+A +
Sbjct: 651 AKADA----------------KVLKDAKTKKVVESKKKA--------------------V 674
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 675 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 726
[83][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 82.4 bits (202), Expect = 2e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 34/207 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQK-------LETRRAEAVAWVKELKRGLA 160
DK+ FYN+ N+ VA LCNH R++ H QM++ L+ +R + L+ LA
Sbjct: 587 DKILFYNRANRTVAILCNHQRSVTKNHDVQMERFAERIKALQYQRMRLRKMMLNLEPKLA 646
Query: 161 KWNKGGKGAKAGAASSPPVE--VTQYMPVKPEILE---------------SMTADEKAQE 289
K + G S V+ T Y K +I + S+ + + +
Sbjct: 647 KSKPELLAKEEGITDSWIVKHHETLYELEKEKIKKKFDRENEKLAAEDPKSVLPESELEV 706
Query: 290 RKRAADLPKVPL---LKSMRGDQLKSNLKRAEERLAKLTSDMEM-------KEDLQTVAL 439
R +AAD K L LKS + D +S++++ E+RL KL + + K++ +T AL
Sbjct: 707 RLKAADELKKALDAELKSKKVDPGRSSMEQLEKRLNKLNERINVMRTQMIDKDENKTTAL 766
Query: 440 GTSKQNYLDPRITVAWCKANEVPVEKI 520
GTSK NY+DPR+T ++ K +VP+EK+
Sbjct: 767 GTSKINYIDPRLTYSFSKREDVPIEKL 793
[84][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 82.0 bits (201), Expect = 2e-14
Identities = 59/172 (34%), Positives = 82/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K K
Sbjct: 423 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKA 475
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 476 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 499
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 500 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 551
[85][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 82.0 bits (201), Expect = 2e-14
Identities = 59/172 (34%), Positives = 82/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K K
Sbjct: 655 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKA 707
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 708 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 731
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 732 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 783
[86][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 82.0 bits (201), Expect = 2e-14
Identities = 59/172 (34%), Positives = 82/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKA 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 670 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 694 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 745
[87][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 82.0 bits (201), Expect = 2e-14
Identities = 59/172 (34%), Positives = 82/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + E ++ L+ K K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTK-------IDEKQKQLSAARKQLKA 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA +S + +KA E KR A +
Sbjct: 670 AKAEHKASHDDK-----------------SKKAVEVKRKA-------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 694 QRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKI 745
[88][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 82.0 bits (201), Expect = 2e-14
Identities = 52/170 (30%), Positives = 82/170 (48%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + V + +R L +
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLKEKIEQKREQVADAQRQL---KDAQR 165
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ + E + AD+K K
Sbjct: 166 DAKRGS-----------------VKERVVADKK------------------------KKQ 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPV 511
L R ++L +L +++ +++ALGTSK NYLDPRI+VAWCK +VP+
Sbjct: 185 LDRLRDQLVRLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234
[89][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 82.0 bits (201), Expect = 2e-14
Identities = 59/209 (28%), Positives = 97/209 (46%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAKWN-KG 175
+K+ YN N+ VA LCNH RT+ GH +QK T R E + W K LKR + + + K
Sbjct: 527 EKMLKYNAANRTVAILCNHQRTVTKGHAASVQK-ATERIEELEWQKIRLKRAILQLDEKQ 585
Query: 176 GKGAKAGAASSPPVEVTQYMPVKPEILE--------SMTADEKAQERKRAADLPKVPL-- 325
K A + Q + ++E + + + ++ ++ +LP+ L
Sbjct: 586 AKKDPKFFAEVTDLVKEQEAAIHKRLIEKEREKYVKKFSRENEKRKFEKQEELPESQLKE 645
Query: 326 ------------------------LKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
S ++LK +++ ++R+ T ++ KED V
Sbjct: 646 WMARVDELEKQYNEELESGKVQLKTNSESAEKLKMQIEKLDQRIETATIQLKDKEDNSQV 705
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
ALGTSK NY+DPR++V +CK VP+EK+
Sbjct: 706 ALGTSKINYIDPRLSVVFCKKYGVPIEKV 734
[90][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 81.6 bits (200), Expect = 3e-14
Identities = 59/172 (34%), Positives = 81/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + KR L KG
Sbjct: 601 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLSAAKREL-------KG 653
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+ K+A + K +
Sbjct: 654 AKADA--------------------KVRKDEKS---KKAVE-------------SKKKAV 677
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R E++L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 678 QRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 729
[91][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 81.6 bits (200), Expect = 3e-14
Identities = 59/172 (34%), Positives = 81/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ + KR L KG
Sbjct: 601 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKEQLSAAKREL-------KG 653
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+ K+A + K +
Sbjct: 654 AKADA--------------------KVRKDEKS---KKAVE-------------SKKKAV 677
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R E++L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 678 QRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 729
[92][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 81.6 bits (200), Expect = 3e-14
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 1/170 (0%)
Frame = +2
Query: 14 FYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKA 193
FYN N+ VA LCNH R++P H+ M KL+ + K LK + + N+ K ++
Sbjct: 837 FYNYANREVAILCNHQRSIPKQHETSMTKLKLQ-------AKMLKEDIQELNEYCKHLQS 889
Query: 194 GAASSPPVEVTQYMPVKPEI-LESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKR 370
+ K E ES T D RK M+ + K+ L
Sbjct: 890 NS--------------KDEFKFESKTKDVNGNPRKLITK-------PGMKLEAAKNKLAT 928
Query: 371 AEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ M +K+ +TVALGTSK NY+DPRITVA+CK E+P+EK+
Sbjct: 929 LKKKQKDHNIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKV 978
[93][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 81.6 bits (200), Expect = 3e-14
Identities = 52/171 (30%), Positives = 82/171 (47%)
Frame = +2
Query: 8 VAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGA 187
+ FYN N+ VA LCNH R++P H M K++ + +KE K+ L K
Sbjct: 675 INFYNNANREVAILCNHQRSIPKQHDTTMSKIKKQIELYNEDIKEYKKYLQHLKKNS--- 731
Query: 188 KAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLK 367
+ K L+ K +E +M+ + K L
Sbjct: 732 ----------DKKFIFVSKVSTLDGTLRPNKVKE--------------NMKEESCKKKLI 767
Query: 368 RAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ L + M++++D +T+ALGTSK NY+DPRITVA+CK E+P+EK+
Sbjct: 768 TLIKKVELLNNQMKVRDDNKTIALGTSKINYMDPRITVAFCKKFEIPIEKV 818
[94][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 81.6 bits (200), Expect = 3e-14
Identities = 53/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + +++ + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IEQKREQIEDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +++ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LERLKEQLIKLEVLETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[95][TOP]
>UniRef100_Q9BVT2 Putative uncharacterized protein (Fragment) n=1 Tax=Homo sapiens
RepID=Q9BVT2_HUMAN
Length = 176
Score = 81.6 bits (200), Expect = 3e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 26 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKS 78
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 79 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 102
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 103 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 154
[96][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 81.6 bits (200), Expect = 3e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 615 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKS 667
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 668 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 691
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 692 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 743
[97][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 81.6 bits (200), Expect = 3e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 615 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKEQLADARRDLKS 667
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 668 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 691
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 692 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 743
[98][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 81.3 bits (199), Expect = 4e-14
Identities = 58/172 (33%), Positives = 77/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R++P MQ L+ +
Sbjct: 512 KLLSYNRANRAVAILCNHQRSIPKTFAKSMQVLQEKID---------------------- 549
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
A VE Q K E T D KA+ + ++ K L
Sbjct: 550 -----AKKKQVEEAQEEVKKAEDEFKDTKDAKAE----------------LNVEKKKKLL 588
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
KR EE+LAK+ KE+ + +ALGTSK NYLDPRITVAWCK +P+E+I
Sbjct: 589 KRLEEQLAKMNIQATDKEENKQIALGTSKLNYLDPRITVAWCKKFGIPIERI 640
[99][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 81.3 bits (199), Expect = 4e-14
Identities = 58/172 (33%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ A + KR L K
Sbjct: 605 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKAQLSAAKREL-------KS 657
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+++ A K +
Sbjct: 658 AKADA--------------------KVRRDEKSKKAVEAK----------------KKAV 681
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R +++L KL +E+ + +ALGTSK NYLDPRI+VAWCK +PVEKI
Sbjct: 682 QRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKI 733
[100][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 81.3 bits (199), Expect = 4e-14
Identities = 58/172 (33%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+T+ A + KR L K
Sbjct: 603 KILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDAKKAQLSAAKREL-------KS 655
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+++ A K +
Sbjct: 656 AKADA--------------------KVRRDEKSKKAVEAK----------------KKAV 679
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R +++L KL +E+ + +ALGTSK NYLDPRI+VAWCK +PVEKI
Sbjct: 680 QRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKI 731
[101][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 81.3 bits (199), Expect = 4e-14
Identities = 52/173 (30%), Positives = 79/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + + + + + K K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEK-------IDQKREQITDAQKQVK 161
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A E Y D+ K
Sbjct: 162 DAQRDAKHGSVKEKVVY-------------------------------------DKKKKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+L KL +++ + +ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LEKLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[102][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus caballus
RepID=UPI0001797824
Length = 765
Score = 80.9 bits (198), Expect = 5e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 615 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 667
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++L+ + + +K+A +
Sbjct: 668 AKADA----------------KVLKDAKTKKVVESKKKA--------------------V 691
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 692 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 743
[103][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 80.9 bits (198), Expect = 5e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 854 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 906
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++L+ + + +K+A +
Sbjct: 907 AKADA----------------KVLKDAKTKKVVESKKKA--------------------V 930
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 931 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 982
[104][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 80.9 bits (198), Expect = 5e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 602 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 654
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++L+ + + +K+A +
Sbjct: 655 AKADA----------------KVLKDAKTKKVVESKKKA--------------------V 678
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 679 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 730
[105][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 80.9 bits (198), Expect = 5e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 619 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 671
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++L+ + + +K+A +
Sbjct: 672 AKADA----------------KVLKDAKTKKVVESKKKA--------------------V 695
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 696 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 747
[106][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 80.9 bits (198), Expect = 5e-14
Identities = 52/173 (30%), Positives = 83/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+KL+ + + + + +R + K
Sbjct: 109 EKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLKEKIDQKREQIADAQRQV---KDAQK 165
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK G+ + E + ++K K
Sbjct: 166 DAKHGS-----------------VKEKLVYEKK------------------------KKM 184
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L + +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 185 LDKLKDQLKKLEVQETDRDENKTIALGTSKLNYLDPRISVAWCKKYDVPIEKI 237
[107][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 80.5 bits (197), Expect = 6e-14
Identities = 57/171 (33%), Positives = 78/171 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P QM ++ + +++ +R + + K
Sbjct: 332 KILSYNRANRAVAVLCNHQRAAPKNFSEQMGRMNEK-------IEKKQRDIQDAKQETKS 384
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AK+ Y K E A KA E K K +
Sbjct: 385 AKS-----------DYKHNKSE------AKRKAYEGK-------------------KKKV 408
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+R +E+L KL KE+ + +ALGTSK NYLDPRITVAWCK VP+EK
Sbjct: 409 ERLQEQLIKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKYSVPIEK 459
[108][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 80.5 bits (197), Expect = 6e-14
Identities = 56/168 (33%), Positives = 77/168 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K A Y+ NK VA LCNH + + H QM+KL ++ K+L + +A+ K
Sbjct: 347 KKATYDAANKEVAILCNHQKGVSKAHDAQMEKLAEKK-------KDLAKQVAEMKK---- 395
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
D+K Q++K AA
Sbjct: 396 ---------------------------KTDDKNQKKKLAA-------------------- 408
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVP 508
+ER +KL M MKE+L+TV+LGTSK NYLDPRIT++WCK +EVP
Sbjct: 409 --LKERQSKLAIQMNMKEELKTVSLGTSKINYLDPRITLSWCKRHEVP 454
[109][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 80.5 bits (197), Expect = 6e-14
Identities = 53/173 (30%), Positives = 84/173 (48%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
D + F+N N+ VA LCNH R++P H M K++ + ++E K+ L K
Sbjct: 719 DLINFFNNANREVAILCNHQRSIPKQHDTTMSKIKKQIEIYNEDMQEYKKYLQYLKKNNN 778
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ S K L+ K +E +M+ + K
Sbjct: 779 EKEFTFVS------------KVVTLDGSLRPNKVKE--------------NMKEESCKKK 812
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L +++ L + M++++D +T+ALGTSK NY+DPRITVA+CK E+P+EKI
Sbjct: 813 LIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQFEIPIEKI 865
[110][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 80.5 bits (197), Expect = 6e-14
Identities = 65/209 (31%), Positives = 99/209 (47%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAV--------- 127
+KV YN N+ VA LCNH RT+ +GH QM+KL R R + +
Sbjct: 630 EKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGDRIKGLRYQKWRVKMMMLDIDPSQK 689
Query: 128 ----------------AWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
AW++E + L + K K K + + +KP+ LE
Sbjct: 690 KKKGSKYFELDEDLDQAWIQEHQAFLIEEQKQ-KITKKFEKDNEKLAADGEKEMKPKELE 748
Query: 260 SMTADEKAQERK--RAADLPKVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
A K E+K + KV + K ++L++N+ + E+R+ ++ E KE+ +
Sbjct: 749 ERLAVLKDMEKKFQKENKTGKVEVEGKGQTVEKLENNVTKLEQRIENMSLQAEDKENNKE 808
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 809 VALGTSKINYIDPRLTVVFTKKFNVPIEK 837
[111][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 80.5 bits (197), Expect = 6e-14
Identities = 56/172 (32%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA K K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARKDLKS 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 670 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 694 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 745
[112][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 80.1 bits (196), Expect = 8e-14
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 670 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 694 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 745
[113][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 80.1 bits (196), Expect = 8e-14
Identities = 63/180 (35%), Positives = 81/180 (45%), Gaps = 7/180 (3%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQM----QKLETRRAEAVAWVKELKRGLAKWN 169
+K+ YN+ N+ VA LCNH R P M K+E R+ + V ELK+ AK
Sbjct: 469 EKLLSYNRANRAVAILCNHQRAPPKTFDQSMANLQSKIEARKEQLVLAKSELKQ--AKKE 526
Query: 170 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE---RKRAADLPKVPLLKSMR 340
KG+ AD K Q RK+ A
Sbjct: 527 AKAKGS---------------------------ADAKLQALVVRKKMA------------ 547
Query: 341 GDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+KR EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK EVPV+KI
Sbjct: 548 -------VKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKI 600
[114][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 80.1 bits (196), Expect = 8e-14
Identities = 56/172 (32%), Positives = 81/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R+ P + MQ L+T+ + K L K
Sbjct: 443 KLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQTK-------IDAKKEQLEK------- 488
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
+ E+ E+ + ++ K A ++ K K L
Sbjct: 489 ------------------AQQELEEAEDEFKDKKDAKAAGNVQKK-----------KKLL 519
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R +E+LAKL KE+ + +ALGTSK NYLDPRI++AWCK VP+EKI
Sbjct: 520 ERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKI 571
[115][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 80.1 bits (196), Expect = 8e-14
Identities = 63/180 (35%), Positives = 81/180 (45%), Gaps = 7/180 (3%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQM----QKLETRRAEAVAWVKELKRGLAKWN 169
+K+ YN+ N+ VA LCNH R P M K+E R+ + V ELK+ AK
Sbjct: 469 EKLLSYNRANRAVAILCNHQRAPPKTFDQSMANLQSKIEARKEQLVLAKSELKQ--AKKE 526
Query: 170 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE---RKRAADLPKVPLLKSMR 340
KG+ AD K Q RK+ A
Sbjct: 527 AKAKGS---------------------------ADAKLQALVVRKKMA------------ 547
Query: 341 GDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+KR EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK EVPV+KI
Sbjct: 548 -------VKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKI 600
[116][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 80.1 bits (196), Expect = 8e-14
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 410 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 462
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 463 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 486
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 487 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 538
[117][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 80.1 bits (196), Expect = 8e-14
Identities = 54/173 (31%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R +P H+ M L+ +
Sbjct: 820 EKLLAYNRANRAVAILCNHQRAVPKTHEKSMSNLKEK----------------------- 856
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E+ + K DL K + + D+ +
Sbjct: 857 -----------------IRAKQEAVETCERELK--------DLKKSNVRDKVAKDKKQKQ 891
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R E+L KL K++ +T+ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 892 LERLREQLNKLELQETDKDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKI 944
[118][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 80.1 bits (196), Expect = 8e-14
Identities = 52/173 (30%), Positives = 89/173 (51%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
D + FYN N+ VA LCNH R++P H+ M+KL ++ E +K + L K
Sbjct: 489 DILRFYNDANREVAILCNHQRSIPKQHESSMEKLLKQQLELQEDLKICEVYLRLLKK--- 545
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+P +T + L ++ + + R K P+ S + ++
Sbjct: 546 --------NPNKSITL------KDLPKLSTETSFNGKPR-----KFPINLSSNSEIIQKK 586
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L + +L+ L +++K+D +TV+L TSK NY+DPRI+VA+CK E+P++K+
Sbjct: 587 LDSIKTKLSNLELKIKIKDDNKTVSLNTSKLNYMDPRISVAFCKKYELPIDKV 639
[119][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 80.1 bits (196), Expect = 8e-14
Identities = 59/173 (34%), Positives = 82/173 (47%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWV-KELKRGLAKWNKGG 178
+K+ Y + N+ VA LCNH R P H QM++L+ EA+ + KEL + + K
Sbjct: 2260 EKLLAYQRANRAVAILCNHQRAAPKTHDEQMERLD----EALVKIQKELDSTIKERKKLK 2315
Query: 179 KGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKS 358
K +A + +D+ K L R D LK
Sbjct: 2316 KDLRA----------------------------------QGSDVSKTDL---NRLDVLKR 2338
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+ R EERL K KE+ + +AL TSK NYLDPRI+VAWCK ++VPV+K
Sbjct: 2339 KVDRLEERLHKKQIAKVDKEENKCIALSTSKLNYLDPRISVAWCKTHDVPVDK 2391
[120][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 80.1 bits (196), Expect = 8e-14
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRDLKS 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 670 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 694 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 745
[121][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 80.1 bits (196), Expect = 8e-14
Identities = 56/172 (32%), Positives = 77/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV YN+ N+ VA LCNH R +P + MQ L+
Sbjct: 444 KVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQK------------------------- 478
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
K E ++ A+ + + +K DL KS Q + L
Sbjct: 479 -------------------KIETKKAQVAEAQVELQKAETDLRMRGDSKSKSFLQKQQRL 519
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ EE+LA+L + KE+ + VALGT+K NYLDPRI++AWCK VPVEKI
Sbjct: 520 LKLEEQLARLCTKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKI 571
[122][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 79.7 bits (195), Expect = 1e-13
Identities = 51/173 (29%), Positives = 74/173 (42%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H M+ L+ +
Sbjct: 839 EKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAK----------------------- 875
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K + + D +++K+A D
Sbjct: 876 -----------------IEAKKQAINDAELDSTYEKKKKALD------------------ 900
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R +E+L KL KE+ + +ALGTSK NYLDPRITVAWCK + VP+EKI
Sbjct: 901 --RLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKI 951
[123][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 79.7 bits (195), Expect = 1e-13
Identities = 56/172 (32%), Positives = 81/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R+ P + MQ L+T+ + K L K
Sbjct: 443 KLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQTK-------IDAKKEQLEK------- 488
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
+ E+ E+ + ++ K A++ K K L
Sbjct: 489 ------------------AQQELEEAEDEFKDKKDAKAEANVQKK-----------KKLL 519
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R +E+LAKL KE+ + +ALGTSK NYLDPRI++AWCK VP+EKI
Sbjct: 520 ERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKI 571
[124][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 79.7 bits (195), Expect = 1e-13
Identities = 59/174 (33%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV YN+ N+ VA LCNH R +P + MQ L+ +
Sbjct: 146 KVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKK------------------------ 181
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE--RKRAADLPKVPLLKSMRGDQLKS 358
+E K ++ E+ +KA+ R R PK L K R
Sbjct: 182 ----------IETK-----KAQVAEAQVELQKAETDLRMRGDSKPKSFLQKQRR------ 220
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L + EE+LA+L + KE+ + VALGT+K NYLDPRI++AWCK VPVEKI
Sbjct: 221 -LLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKI 273
[125][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 79.7 bits (195), Expect = 1e-13
Identities = 59/174 (33%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV YN+ N+ VA LCNH R +P + MQ L+ +
Sbjct: 443 KVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKK------------------------ 478
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE--RKRAADLPKVPLLKSMRGDQLKS 358
+E K ++ E+ +KA+ R R PK L K R
Sbjct: 479 ----------IETK-----KAQVAEAQVELQKAETDLRMRGDSKPKSFLQKQRR------ 517
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L + EE+LA+L + KE+ + VALGT+K NYLDPRI++AWCK VPVEKI
Sbjct: 518 -LLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKI 570
[126][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 79.7 bits (195), Expect = 1e-13
Identities = 50/173 (28%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 834 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 870
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E ++ +++ K+ L D+L+
Sbjct: 871 -----------------IKAKREAIEKCESEYNSRDEKKGKQL-----------DRLRDQ 902
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
LK+ E + +++ +T+ALGTSK NYLDPRI+VAWCK N+VP+EKI
Sbjct: 903 LKKLELQETD-------RDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKI 948
[127][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 79.7 bits (195), Expect = 1e-13
Identities = 58/209 (27%), Positives = 96/209 (45%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV +N N+ VA LCNH RT+ H +QK+ + E + LK+ + K K
Sbjct: 621 EKVVKFNAANRTVAILCNHQRTVSKNHGNSVQKINDKLRELIWQKIRLKKMILKLEPKLK 680
Query: 182 GA------KAGAASSPPVEVTQYMPV----------------------KP--------EI 253
+ S+ +E ++ + KP E
Sbjct: 681 KKDPKYFEELEDLSNEEIEHIHHLVIERHRQQVQKKFERDNEKLKLEKKPLLKKKDIKEK 740
Query: 254 LESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
L+ +T EK +++ P++P K ++LK+ ++ E R+ T ++ KED V
Sbjct: 741 LDKITELEKEYKKELKTGKPEIP--KGATVEKLKTQVENMENRIVSTTLQLKDKEDNSEV 798
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+LGTSK NY+DPR+TV + K +VP+EK+
Sbjct: 799 SLGTSKMNYIDPRLTVMFSKKFDVPIEKL 827
[128][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 79.7 bits (195), Expect = 1e-13
Identities = 59/174 (33%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
KV YN+ N+ VA LCNH R +P + MQ L+ +
Sbjct: 444 KVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKK------------------------ 479
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE--RKRAADLPKVPLLKSMRGDQLKS 358
+E K ++ E+ +KA+ R R PK L K R
Sbjct: 480 ----------IETK-----KAQVAEAQVELQKAETDLRMRGDSKPKSFLQKQRR------ 518
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L + EE+LA+L + KE+ + VALGT+K NYLDPRI++AWCK VPVEKI
Sbjct: 519 -LLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKI 571
[129][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 79.3 bits (194), Expect = 1e-13
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 608 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKS 660
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 661 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 684
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 685 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 736
[130][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 79.3 bits (194), Expect = 1e-13
Identities = 61/189 (32%), Positives = 93/189 (49%), Gaps = 16/189 (8%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV FYN+ N+ VA LCNH R+L H M K++ + AE + KE + + KG K
Sbjct: 810 EKVLFYNRCNREVAILCNHQRSLSKTHTETMGKIDEKIAE---FKKEKLQQQIAYLKG-K 865
Query: 182 GAKAGAASSPPVEVTQYMPVKPEIL---ESMTADEKAQERKR--------AADLPKVPLL 328
G K + S E T + E+ ++DE +KR A D + P
Sbjct: 866 GKKPVLSDSESDEDTPKKATPKKATPKKETKSSDEATPNKKRKKDDDEEEADDFKETPKK 925
Query: 329 KSMRG-----DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCK 493
K R ++ K+ ++R + + K K++L++VAL TSK NY+DPRIT AW K
Sbjct: 926 KVKRALPDSVEKCKAAIERVDTSINKWNIKKTEKDELKSVALTTSKINYIDPRITAAWAK 985
Query: 494 ANEVPVEKI 520
+ + K+
Sbjct: 986 RVGLDIGKL 994
[131][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 79.3 bits (194), Expect = 1e-13
Identities = 49/173 (28%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 444 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 480
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E + A+ +++ K+
Sbjct: 481 -----------------IKAKREAINKCEAEYHSRDEKKG------------------KQ 505
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK N+VP+EKI
Sbjct: 506 LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKI 558
[132][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 79.3 bits (194), Expect = 1e-13
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKS 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 670 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 694 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 745
[133][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 79.3 bits (194), Expect = 1e-13
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 617 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKS 669
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++++ + + +K+A +
Sbjct: 670 AKADA----------------KVMKDAKTKKVVESKKKA--------------------V 693
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 694 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 745
[134][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 79.0 bits (193), Expect = 2e-13
Identities = 60/174 (34%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+ +
Sbjct: 539 KILSYNRANRAVAILCNHQRATPKTFEKSMQNLQAK------------------------ 574
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRA-ADLPKVPLLKSMRG-DQLKS 358
+ K E L DE E KRA AD +KS ++ K
Sbjct: 575 ----------------IDAKKEQL-----DEAVTELKRAKADHKAKKDIKSKSNLEKKKK 613
Query: 359 NLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ EE+L KL+ KE+ + +ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 614 LLQKIEEQLMKLSVQATDKEENKQIALGTSKLNYLDPRISVAWCKKFGVPIEKI 667
[135][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 79.0 bits (193), Expect = 2e-13
Identities = 56/168 (33%), Positives = 75/168 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K A Y+ NK VA LCNH + + H QM KL ++ + + ++ K NK
Sbjct: 627 KKAKYDAANKEVAILCNHQKGVSKAHDEQMGKLNDKKKDLAKQITDM-----KKNK---- 677
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
D+K Q++K A
Sbjct: 678 -----------------------------DDKNQKKKLTA-------------------- 688
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVP 508
+ER AKL MEMKE+L+TV+LGTSK NYLDPRIT++WCK +EVP
Sbjct: 689 --LKERAAKLAIQMEMKEELKTVSLGTSKINYLDPRITLSWCKRHEVP 734
[136][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 79.0 bits (193), Expect = 2e-13
Identities = 52/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R +P H M L+ +
Sbjct: 815 EKMLAYNRANRAVAILCNHQRAVPKTHDKSMSNLKEK----------------------- 851
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ +K E +E T + ++ KR + S+ D+ +
Sbjct: 852 -----------------IRLKKEAVE--TCQRELKDMKRGGSVKG-----SVDRDKKQKQ 887
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 888 LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFDVPIEKI 940
[137][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 79.0 bits (193), Expect = 2e-13
Identities = 62/209 (29%), Positives = 98/209 (46%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAV--------- 127
+KV YN N+ VA LCNH RT+ +GH QM+KL R R + +
Sbjct: 634 EKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGDRIKGLRYQKWRVKMMMLDLDPSQK 693
Query: 128 ----------------AWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
AW++E + L + K K K + + +KP+ L+
Sbjct: 694 KKKGAKYFELDDDLDQAWIQEHQAFLVEEQK-QKITKKFEKENEKLAAEGEKEMKPKELD 752
Query: 260 SMTADEKAQERKRAADLPKVPLLKSMRG---DQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
A K E+K + + +G ++L++N+ + E+R+ ++ E KE+ +
Sbjct: 753 ERLAVLKDMEKKFQKENKTGKVEAEGKGQTIEKLENNVAKLEQRIETMSLQAEDKENNKE 812
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 813 VALGTSKINYIDPRLTVVFTKKFNVPIEK 841
[138][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 78.6 bits (192), Expect = 2e-13
Identities = 55/172 (31%), Positives = 76/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P QM+ L+ + + +KE K+GL
Sbjct: 290 KMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQEKIDKKHLDIKEAKKGL--------- 340
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
+K E S K K+A +
Sbjct: 341 ----------------KAIKSEYKNSRNEKLKLAMEKKA------------------KQV 366
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R E+LAKL KE+ + +ALGTSK NYLDPRI+VAW K +VP+EK+
Sbjct: 367 ERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKV 418
[139][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 78.6 bits (192), Expect = 2e-13
Identities = 55/172 (31%), Positives = 76/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P QM+ L+ + + +KE K+GL
Sbjct: 729 KMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQEKIDKKHLDIKEAKKGL--------- 779
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
+K E S K K+A +
Sbjct: 780 ----------------KAIKSEYKNSRNEKLKLAMEKKA------------------KQV 805
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R E+LAKL KE+ + +ALGTSK NYLDPRI+VAW K +VP+EK+
Sbjct: 806 ERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKV 857
[140][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 78.6 bits (192), Expect = 2e-13
Identities = 50/173 (28%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
D + FYN N+ VA LCNH R++P H+ M+K+ ++ E +K + L K K
Sbjct: 471 DILRFYNDANREVAILCNHQRSVPKQHESSMEKMIKQQQELEEDLKICEAFLKILKKNNK 530
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
M P++ ++ + K + K P+ + D ++
Sbjct: 531 SVT--------------MNDLPKLSTEVSFNGKQR---------KYPINLNSSLDVVQKK 567
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + +++ L +++K+D +TVAL TSK NY+DPRI+VA+CK ++P++KI
Sbjct: 568 IDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKI 620
[141][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 78.2 bits (191), Expect = 3e-13
Identities = 56/172 (32%), Positives = 78/172 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 631 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKDQLANARRDLKS 683
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A ++ +K E K+ A +
Sbjct: 684 AKADAK-----------------VQRDAKSKKVVETKKKA-------------------V 707
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 708 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 759
[142][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 78.2 bits (191), Expect = 3e-13
Identities = 55/172 (31%), Positives = 76/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+T+ + K LA + K
Sbjct: 766 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTK-------IDAKKDQLADARRDLKS 818
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A V+ + + K K +
Sbjct: 819 AKAEAKVRKDVKTKKVVETK------------------------------------KKAV 842
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 843 QRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 894
[143][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 78.2 bits (191), Expect = 3e-13
Identities = 52/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R P + MQ L+ + + ++E ++ L + + K
Sbjct: 45 EKILSYNRANRAVAILCNHQRAAPKTFEKSMQLLQEKIQKKKEQIEEARKELKEAKQVDK 104
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ +S K E+K+ A
Sbjct: 105 DTPSDKSS------------------------KLVEKKQKA------------------- 121
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++R ++L KL +E+ + +ALGTSK NYLDPRITVAWCK ++VP+EKI
Sbjct: 122 VQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKI 174
[144][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 78.2 bits (191), Expect = 3e-13
Identities = 52/173 (30%), Positives = 81/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R P + MQ L+ + + ++E ++ L + + K
Sbjct: 449 EKILSYNRANRAVAILCNHQRAAPKTFEKSMQLLQEKIQKKKEQIEEARKELKEAKQVDK 508
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ +S K E+K+ A
Sbjct: 509 DTPSDKSS------------------------KLVEKKQKA------------------- 525
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++R ++L KL +E+ + +ALGTSK NYLDPRITVAWCK ++VP+EKI
Sbjct: 526 VQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKI 578
[145][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 78.2 bits (191), Expect = 3e-13
Identities = 36/78 (46%), Positives = 58/78 (74%)
Frame = +2
Query: 275 EKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQ 454
EK Q++K+ + ++ L+ + D K+ ++ +ERL+KL M+MK++L++V+LGTSK
Sbjct: 534 EKLQDKKKIIE-KEIAALRRDKKDTNKAKIRTLKERLSKLELQMKMKDELKSVSLGTSKI 592
Query: 455 NYLDPRITVAWCKANEVP 508
NY+DPRIT+AWCK N+VP
Sbjct: 593 NYMDPRITIAWCKHNDVP 610
[146][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 78.2 bits (191), Expect = 3e-13
Identities = 50/173 (28%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
D + FYN N+ VA LCNH R++P H+ M+K+ ++ E +K + L K K
Sbjct: 483 DILRFYNDANREVAILCNHQRSVPKQHESSMEKMIKQQQELEEDLKICEAFLKILKKNNK 542
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
V ++ + E+ S ++ K P+ + D ++
Sbjct: 543 S----------VTISDLPKLSTEV--SFNGKQR-----------KYPINLNSSLDVVQKK 579
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + +++ L +++K+D +TVAL TSK NY+DPRI+VA+CK ++P++KI
Sbjct: 580 IDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKI 632
[147][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 78.2 bits (191), Expect = 3e-13
Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAW----VKELKRGLAKWN 169
+KV YN N+ VA LCNH RT+ +GH QM+KL + R + +++ +K++ L
Sbjct: 659 EKVKQYNDANRKVAILCNHKRTVAAGHANQMEKL-SERIKGLSYQKWRIKQMMIDLDPKI 717
Query: 170 KGGKGAKAGAASSPPVE--VTQYMP--------------------VKPEILESMTADEKA 283
K KG + S E V Q+ ++ E + M A E
Sbjct: 718 KKKKGPEFFQLDSDLDEEWVKQHQAFLVEEQRQKIQKKFEKENEKLRAEGEKEMKAKELE 777
Query: 284 QERKRAADLP----------KVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
Q + A +L KV + K M ++L++NL + ++R+ ++ + KE+ +
Sbjct: 778 QRLEAAKELEAKFKKENKTKKVEVEGKGMTIEKLENNLAKLDQRIETMSLQAQDKEENKE 837
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 838 VALGTSKINYIDPRLTVVFSKKFDVPIEK 866
[148][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 77.8 bits (190), Expect = 4e-13
Identities = 55/172 (31%), Positives = 79/172 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 625 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRELKS 677
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+++ + K +
Sbjct: 678 AKADA--------------------KVRRDEKSKKTVESK----------------KKAV 701
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 702 QRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 753
[149][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 77.8 bits (190), Expect = 4e-13
Identities = 48/173 (27%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 445 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 481
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E ++ +++ K+
Sbjct: 482 -----------------IKAKREAIEKCESEYHSRDEKKG------------------KQ 506
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R ++L KL +++ +T+ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 507 LERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKI 559
[150][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 77.8 bits (190), Expect = 4e-13
Identities = 48/173 (27%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 838 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 874
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E ++ +++ K+
Sbjct: 875 -----------------IKAKREAIEKCESEYHSRDEKKG------------------KQ 899
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R ++L KL +++ +T+ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 900 LERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKI 952
[151][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 77.8 bits (190), Expect = 4e-13
Identities = 53/173 (30%), Positives = 83/173 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
DK+ FY++ N+ VA LCNH +T+ + K+E R + KEL L K K G
Sbjct: 546 DKLNFYDEANRNVAILCNHQKTVGKNFDVMVGKMEQRINVYKDYEKELHTHLNKCKKNGV 605
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A E E+ + K + K P K ++++
Sbjct: 606 NA----------------------YEKEVILEEKDDGKHKMFVKKFPGTK----EKIQEA 639
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+++ ++++ + + + KE + +ALGTSK NY DPRI+V WCK EVPVEK+
Sbjct: 640 IEKIKKKIDEEQNKKQSKEKNKEIALGTSKTNYNDPRISVVWCKKWEVPVEKV 692
[152][TOP]
>UniRef100_C7E3P0 Topoisomerase family protein (Fragment) n=1 Tax=Caenorhabditis
brenneri RepID=C7E3P0_CAEBE
Length = 159
Score = 77.8 bits (190), Expect = 4e-13
Identities = 55/172 (31%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R++ H M+KLE + +K+ K+
Sbjct: 17 KILSYNRANRQVAILCNHQRSVSKTHDQAMEKLEQK-------IKDKKK----------- 58
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
E+ E+ E+A + R AD K +
Sbjct: 59 ---------------------EVKEA----EEALKHARGADKEKA-----------QKKY 82
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
R +E+L KL K++ + +ALGTSK NYLDPRITVAWCK ++VP+EK+
Sbjct: 83 DRLKEQLKKLKIARTDKDENKQIALGTSKLNYLDPRITVAWCKEHDVPLEKV 134
[153][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 77.8 bits (190), Expect = 4e-13
Identities = 48/173 (27%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 445 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 481
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E ++ +++ K+
Sbjct: 482 -----------------IKAKREAIEKCESEYHSRDEKKG------------------KQ 506
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R ++L KL +++ +T+ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 507 LERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKI 559
[154][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 77.8 bits (190), Expect = 4e-13
Identities = 48/173 (27%), Positives = 79/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 833 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 869
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E ++ A+ +++ K+
Sbjct: 870 -----------------IKAKREAIKKCEAEYHSRDEKKG------------------KQ 894
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +++L KL +++ +T+ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 895 LERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKI 947
[155][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 77.8 bits (190), Expect = 4e-13
Identities = 48/173 (27%), Positives = 78/173 (45%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P H+ M+ L+ +
Sbjct: 836 EKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEK----------------------- 872
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K E +E ++ +++ K+
Sbjct: 873 -----------------IKAKREAIEKCESEYHSRDEKKG------------------KQ 897
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R ++L KL +++ +T+ALGTSK NYLDPRI+VAWCK ++VP+EKI
Sbjct: 898 LERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKI 950
[156][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 77.4 bits (189), Expect = 5e-13
Identities = 55/172 (31%), Positives = 75/172 (43%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + MQ L+ + V E K L K
Sbjct: 505 KILSYNRANRAVAILCNHQRATPKTFEKSMQNLQLKIEAKKKQVAEAKAEL-------KQ 557
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
A+AG ++ + +LE +
Sbjct: 558 ARAGHKCRGDDRSRSFLEKRERLLEKL--------------------------------- 584
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
EE+L +L++ KE+ + VALGTSK NYLDPRI+VAWCK VPVE+I
Sbjct: 585 ---EEQLMRLSTQATDKEESKQVALGTSKLNYLDPRISVAWCKRFGVPVERI 633
[157][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 77.4 bits (189), Expect = 5e-13
Identities = 54/169 (31%), Positives = 76/169 (44%)
Frame = +2
Query: 14 FYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKA 193
FYN N+ VA LCNH R++P H+ M KL+ + ++EL KG
Sbjct: 833 FYNYANREVAILCNHQRSIPKQHETSMTKLKLQAKMLKEDIQELNEYCKHLQSNSKGEFK 892
Query: 194 GAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRA 373
+ + V P K M + + L PL K + +K
Sbjct: 893 FESKTKDVNGN---PRKLITKPGMKLEAAKNKLSTLNYLCFAPLKKKQKDHAIK------ 943
Query: 374 EERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
M +K+ +TVALGTSK NY+DPRITVA+CK E+P+EK+
Sbjct: 944 ----------MTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKV 982
[158][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 77.4 bits (189), Expect = 5e-13
Identities = 58/172 (33%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+ + + K LA + K
Sbjct: 671 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGK-------IDAKKDQLADARREFKS 723
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK ++ L++S K +
Sbjct: 724 AKADA--------------------KVRRDEKTKK-----------LVESK-----KKAV 747
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 748 QRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKI 799
[159][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 77.4 bits (189), Expect = 5e-13
Identities = 59/172 (34%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R + G MQKLE + +K+ K+ + K
Sbjct: 592 KILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQK-------IKDKKKEV-------KE 637
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
A+A S+ E EKAQ++ D+LK L
Sbjct: 638 AEAALKSARGAE-----------------KEKAQKKY----------------DRLKEQL 664
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K KL K++ + +ALGTSK NY+DPRITVAWCK EVP+EK+
Sbjct: 665 K-------KLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKV 709
[160][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 77.4 bits (189), Expect = 5e-13
Identities = 59/172 (34%), Positives = 80/172 (46%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R + G MQKLE + +K+ K+ + K
Sbjct: 664 KILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQK-------IKDKKKEV-------KE 709
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
A+A S+ E EKAQ++ D+LK L
Sbjct: 710 AEAALKSARGAE-----------------KEKAQKKY----------------DRLKEQL 736
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K KL K++ + +ALGTSK NY+DPRITVAWCK EVP+EK+
Sbjct: 737 K-------KLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKV 781
[161][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 77.0 bits (188), Expect = 7e-13
Identities = 49/164 (29%), Positives = 80/164 (48%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R++P GH+ M+KL+ + + + E++R + K
Sbjct: 143 EKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLKEKIEQKREQINEMQRQV-------K 195
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
A+ A + + E M D+K K
Sbjct: 196 DAQRDARNG-------------SVKEKMVFDKK------------------------KKA 218
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCK 493
L++ +E++ +L K++ +++ALGTSK NYLDPRI+VAWCK
Sbjct: 219 LEKLKEQMIRLEVQETDKDENKSIALGTSKLNYLDPRISVAWCK 262
[162][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 77.0 bits (188), Expect = 7e-13
Identities = 62/209 (29%), Positives = 95/209 (45%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH RT P H +Q++ E LKR + + +K K
Sbjct: 534 EKVVKYNAANREVAILCNHQRTKPKSHDMGVQRISDNIRELFWQKLRLKRMILELDKSLK 593
Query: 182 GAK---------AGAASSPPVE----------------------VTQYMPVKPEIL---E 259
K ++ T+ P+ PE + +
Sbjct: 594 KTKPYYFEELDDLSVEEEQAIQDRVIAKEREKATKKFTRDNEKLKTEDSPLLPEAMLEEK 653
Query: 260 SMTADEKAQERKRAADLPKVPLLKS--MRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
DE A E K+ K P +KS + ++L+S +++ E+R+ T ++ KED V
Sbjct: 654 LKKIDELAAEYKKELKTRK-PEIKSVTVTVEKLESQVEKLEQRIRNATLLLQDKEDNSQV 712
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
ALGTSK NY+DPR+T + K +VP+EK+
Sbjct: 713 ALGTSKLNYIDPRLTAMFSKKYDVPIEKL 741
[163][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 76.6 bits (187), Expect = 9e-13
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK--------ELKRGL 157
+KV +N N+ VA LCNH RT+ H +Q++ R E + W K EL+ GL
Sbjct: 526 EKVVRFNAANRTVAILCNHQRTVSKTHGHSVQRIHDRIKEMM-WQKIRTKKMILELEPGL 584
Query: 158 AKWNKGG--------------------KGAKAGAASSPPVEVTQYMPVKPEILESMTADE 277
+ + + A+ A E + E+L S DE
Sbjct: 585 RRKDPKYFEELEDLSKEDEQHVHHLLLERAREQAQRKFERENQKLKAEGKELLSSSVLDE 644
Query: 278 KA-----QERKRAADLPK-VPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
K QE+ A +L P++KS ++LK+ +++ + R+ T ++ KED V+
Sbjct: 645 KMEKIKEQEKDLAEELKTGKPVMKSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVS 704
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+TV + K +VP+EK+
Sbjct: 705 LGTSKLNYIDPRLTVMFSKKFDVPIEKL 732
[164][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 76.6 bits (187), Expect = 9e-13
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGH-------KGQMQKLETRRAEAVAWVKELKRGLA 160
+K+ YN N+ VA LCNH RT+ GH ++Q+LE ++ + +L + L
Sbjct: 516 EKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLL 575
Query: 161 K-----------WNKGGKGAKAGAASSPPVEVTQYMPV---------KPEILESMT---- 268
K K + +E Q V K E+L
Sbjct: 576 KKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEW 635
Query: 269 ---ADEKAQERKRAADLPKVPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
DEK QE ++ +V L S +++K+ +++ E+R+ + ++ KE+ V+
Sbjct: 636 LEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVS 695
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR++V +CK +VP+EKI
Sbjct: 696 LGTSKINYIDPRLSVVFCKKYDVPIEKI 723
[165][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 76.6 bits (187), Expect = 9e-13
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGH-------KGQMQKLETRRAEAVAWVKELKRGLA 160
+K+ YN N+ VA LCNH RT+ GH ++Q+LE ++ + +L + L
Sbjct: 540 EKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLL 599
Query: 161 K-----------WNKGGKGAKAGAASSPPVEVTQYMPV---------KPEILESMT---- 268
K K + +E Q V K E+L
Sbjct: 600 KKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEW 659
Query: 269 ---ADEKAQERKRAADLPKVPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
DEK QE ++ +V L S +++K+ +++ E+R+ + ++ KE+ V+
Sbjct: 660 LEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVS 719
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR++V +CK +VP+EKI
Sbjct: 720 LGTSKINYIDPRLSVVFCKKYDVPIEKI 747
[166][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 76.6 bits (187), Expect = 9e-13
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK--------ELKRGL 157
+KV +N N+ VA LCNH RT+ H +Q++ R E + W K EL+ GL
Sbjct: 526 EKVVRFNAANRTVAILCNHQRTVSKTHGHSVQRIHDRIKEMM-WQKIRTKKMILELEPGL 584
Query: 158 AKWNKGG--------------------KGAKAGAASSPPVEVTQYMPVKPEILESMTADE 277
+ + + A+ A E + E+L S DE
Sbjct: 585 RRKDPKYFEELEDLSKEDEQHVHHLLLERAREQAQRKFERENQKLKAEGKELLSSSVLDE 644
Query: 278 KA-----QERKRAADLPK-VPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
K QE+ A +L P++KS ++LK+ +++ + R+ T ++ KED V+
Sbjct: 645 KMEKIKEQEKDLAEELKTGKPVMKSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVS 704
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+TV + K +VP+EK+
Sbjct: 705 LGTSKLNYIDPRLTVMFSKKFDVPIEKL 732
[167][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae RepID=TOP1_YEAST
Length = 769
Score = 76.6 bits (187), Expect = 9e-13
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGH-------KGQMQKLETRRAEAVAWVKELKRGLA 160
+K+ YN N+ VA LCNH RT+ GH ++Q+LE ++ + +L + L
Sbjct: 540 EKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLL 599
Query: 161 K-----------WNKGGKGAKAGAASSPPVEVTQYMPV---------KPEILESMT---- 268
K K + +E Q V K E+L
Sbjct: 600 KKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEW 659
Query: 269 ---ADEKAQERKRAADLPKVPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
DEK QE ++ +V L S +++K+ +++ E+R+ + ++ KE+ V+
Sbjct: 660 LEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVS 719
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR++V +CK +VP+EKI
Sbjct: 720 LGTSKINYIDPRLSVVFCKKYDVPIEKI 747
[168][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 76.3 bits (186), Expect = 1e-12
Identities = 56/172 (32%), Positives = 81/172 (47%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+ + + + +R L K
Sbjct: 634 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLMDARREL-------KS 686
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+++ L++S K +
Sbjct: 687 AKADA--------------------KVKRDEKSKK-----------LVESK-----KKAV 710
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 711 QRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGIPIEKI 762
[169][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 76.3 bits (186), Expect = 1e-12
Identities = 51/173 (29%), Positives = 87/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH R++ + ++ L + + + + K+ L K
Sbjct: 367 EKVVEYNNANREVAILCNHQRSVSKAQETTLENL----GDKLQTLNDQKKALKK------ 416
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ I+E+ +D+K ++ A + K + +Q+
Sbjct: 417 -------------------ILKVIMEN--SDKKIPMKEDATKAGHLWEKKPTK-EQVTKR 454
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ E++ K+ +++ K+D + V+LGTSK NY+DPRI+VAWCK NEVP+EKI
Sbjct: 455 ITAWSEKIKKMELNIKHKDDNKEVSLGTSKLNYMDPRISVAWCKRNEVPIEKI 507
[170][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 76.3 bits (186), Expect = 1e-12
Identities = 59/175 (33%), Positives = 80/175 (45%), Gaps = 3/175 (1%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R + G M KLE + V LKR
Sbjct: 683 KILSYNRANRQVAILCNHQRAVSKGFDESMAKLEQK-------VMSLKR----------- 724
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
S + Q K E+ E+ A LKS RG + +
Sbjct: 725 ------KSFFRLIFQIKDKKAEVKEAEAA------------------LKSARGAEKEKAQ 760
Query: 365 KRAE---ERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K+ + E+L KL K++ + +ALGTSK NY+DPRITVAWCK EVP+E++
Sbjct: 761 KKYDQKKEQLKKLKIQRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLERV 815
[171][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 76.3 bits (186), Expect = 1e-12
Identities = 64/213 (30%), Positives = 97/213 (45%), Gaps = 40/213 (18%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-------------E 142
+K+ YN N+ VA LCNH RT+ H MQK T + E W K E
Sbjct: 503 EKMVRYNAANRAVAILCNHQRTVGRSHAQSMQKA-TEKIEEYQWQKIRYKKAILQLDESE 561
Query: 143 LK----------------------RGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL 256
LK R L + + + A E + +P L
Sbjct: 562 LKANPKFFKEINDLTKEEQMSIHKRVLEREREKYQKKFARENEKRKFEGEELLPESQ--L 619
Query: 257 ESMTADEKAQERKRAADLPK-----VPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKED 421
ES AD + ++ +L P L+S+ ++LK+ + + E+R+ + M+ KED
Sbjct: 620 ESWLADVEEMGKEYVEELETGLVTVKPTLQSV--EKLKAQIDKLEQRIRTTSIQMKDKED 677
Query: 422 LQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
TVAL TSK +Y+DPR++VA+CK +VP+EK+
Sbjct: 678 NSTVALSTSKISYIDPRLSVAFCKKYDVPLEKV 710
[172][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 75.9 bits (185), Expect = 2e-12
Identities = 56/172 (32%), Positives = 79/172 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P + M L+++ + K LA + K
Sbjct: 616 KILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKEQLADARRELKS 668
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
AKA A + DEK+ K+A + K +
Sbjct: 669 AKADA--------------------KVRRDEKS---KKAV-------------ESKKKAV 692
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L KL +E+ + +AL TSK NYLDPRI+VAWCK +P+EKI
Sbjct: 693 QRIEEQLMKLEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWGIPIEKI 744
[173][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 75.9 bits (185), Expect = 2e-12
Identities = 52/168 (30%), Positives = 73/168 (43%)
Frame = +2
Query: 17 YNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAG 196
YN+ N+ VA LCNH R +P H+ M+ L+ + +KE K L K
Sbjct: 615 YNRANRQVAILCNHQRAVPKSHEKSMENLKAKIKAKKTELKEAKEELEK----------- 663
Query: 197 AASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAE 376
S TA ++A +R + R +
Sbjct: 664 -------------------AHSDTAKQRATKR-----------------------VDRVK 681
Query: 377 ERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
E+L KL K++ + +AL TSK NYLDPRI+VAWCK +VP+EKI
Sbjct: 682 EQLRKLKIQRTDKDENKQIALSTSKLNYLDPRISVAWCKKYQVPIEKI 729
[174][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 75.9 bits (185), Expect = 2e-12
Identities = 59/210 (28%), Positives = 102/210 (48%), Gaps = 37/210 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAKW--NK 172
+K+ YN N+ VA LCNH R++ GH ++K+ ++ E + W K LK+G+ + ++
Sbjct: 515 EKLLKYNAANRAVAILCNHQRSVTKGHAQSVEKM-NQKIEELLWQKIRLKKGILQLEPSR 573
Query: 173 GGKGAKAGAASSPPVEVTQY--------------------------------MPVKPEIL 256
K K + +V Q +P K E+
Sbjct: 574 AQKNKKYFKEINDMTKVEQATIHKRIVDRERERLKKKFERDNEKLVAEKKDPLP-KTELK 632
Query: 257 ESM-TADEKAQERKRAADLPKVPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
E + D+ ++ K KV L +M+ ++L+ +++ EER+ + ++ KE+
Sbjct: 633 EWLKKVDDLEKQYKTELKTGKVELKATMQSVEKLEKQVEKLEERIKTSSIQLKDKEENSQ 692
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEKI 520
V+LGTSK NY+DPR++V +CK VP+EKI
Sbjct: 693 VSLGTSKINYIDPRLSVVFCKKYNVPIEKI 722
[175][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 75.5 bits (184), Expect = 2e-12
Identities = 61/210 (29%), Positives = 97/210 (46%), Gaps = 37/210 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK------------EL 145
+KV +N N+ VA LCNH RT+ H +QK+ + E + W K +L
Sbjct: 549 EKVVKFNAANRTVAILCNHQRTVSKNHSNTVQKINDKLKELM-WQKIRLKKMILVLEPKL 607
Query: 146 KRGLAKW--------------------NKGGKGAKAGAASSPPVEVTQYMPV--KPEILE 259
K+ AK+ N+ + + + P+ K +I E
Sbjct: 608 KKKDAKYFEEIDDLIKEDIEHIHHTIINRQREQVQKKFERDNEKLKLEGKPLLTKKDIKE 667
Query: 260 SM---TADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
M T EK +++R P VP K+ ++LK ++ E R+ + ++ KED
Sbjct: 668 KMDKITELEKEYKQERKTGKPVVP--KNATVEKLKGQIETLENRILTTSFQLKDKEDNSE 725
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEKI 520
V+LGTSK NY+DPR+TV + K +VP+EK+
Sbjct: 726 VSLGTSKMNYIDPRLTVMFSKKFDVPIEKL 755
[176][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 75.1 bits (183), Expect = 3e-12
Identities = 53/173 (30%), Positives = 71/173 (41%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
DK+ YN+ N+ VA LCNH RT+ QM L + + +KE K+
Sbjct: 409 DKILIYNRSNRAVAILCNHQRTVSKTFDKQMSNLREKIEKKEQQLKEAKK---------- 458
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ K ++ E K KR K
Sbjct: 459 ---------------EEKRAKSDLKERKDESSKKLYEKR------------------KKK 485
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ +L KL K + + VAL TSK NY+DPRI+VAWCK NEVPVEK+
Sbjct: 486 TEMLNRQLHKLNLTETDKVENKEVALSTSKLNYMDPRISVAWCKKNEVPVEKV 538
[177][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 75.1 bits (183), Expect = 3e-12
Identities = 58/209 (27%), Positives = 94/209 (44%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV +N N+ VA LCNH RT+ GH +QK+ + E + LKR + K
Sbjct: 550 EKVVKFNAANRTVAILCNHQRTVSKGHGSSVQKINDKLKELMWQKIRLKRMILVLEPKLK 609
Query: 182 GAKA---------GAASSPPVEVTQYMPVKPEILESMTAD-------------EKAQERK 295
++ + T + ++L+ M D EK+ E K
Sbjct: 610 NKQSHYFCEIDDLAKEDEEHIHHTVIARQREQVLKKMQRDNEKLKLEKQEILTEKSDEIK 669
Query: 296 RA------------ADL--PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
A+L K + K++ ++L+ ++ E R+ T ++ KED V
Sbjct: 670 EKMAKIDDLEKEYKAELNGAKPEVKKNLTVEKLQQQVEVIENRIVTTTLQLKDKEDNSEV 729
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+LGTSK NY+DPR+TV + K +VP+EK+
Sbjct: 730 SLGTSKMNYIDPRLTVMFSKKFDVPIEKL 758
[178][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 74.7 bits (182), Expect = 4e-12
Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 43/216 (19%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+K+A YN N+ VA LCNH +++ G +G K E +
Sbjct: 653 EKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAEDKIRALKYQRLKLRLQLFSLNPKIK 712
Query: 113 -------------------RAEAVAWVKELKRGLAKWNKGGKGAKA-GAASSPPVEVTQY 232
R EA K L+ KW+ + G E+
Sbjct: 713 KKHPELAEDESDVDDEFMERHEAELLEKALENAKKKWDTDNVKLEGDGKKKKTKGELD-- 770
Query: 233 MPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEM 412
E L + A+ K +++R A K+ + ++L + + R +ER+A ++
Sbjct: 771 -----ERLSEIKAEFKELKKERKAK--KIDAKRGATEEKLLAQVARIDERIATAKVQLQD 823
Query: 413 KEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ L+ VALGTSK NY+DPR+TVAW K +VP+EK+
Sbjct: 824 RDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKL 859
[179][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 74.3 bits (181), Expect = 5e-12
Identities = 58/173 (33%), Positives = 88/173 (50%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+ V FYN N+ VA LCNH R P H+ M++L+ + A+ A ++ L +G +
Sbjct: 489 EMVKFYNDANRRVAILCNHQRAPPKQHEAGMERLKKKLADQEATLRGL--------EGRR 540
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
G S V+ EI+ EK E+ D L++ ++ +L
Sbjct: 541 DELLGKTVSKDVK---------EIIV-----EKKLEKSNNMD----SLVRKIKSQKL--- 579
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
A ER +D KED +TV+L TSK NY+DPRI+VA+CK+++ P+EKI
Sbjct: 580 ---AAERTKIQIAD---KEDNKTVSLTTSKINYMDPRISVAFCKSHDCPIEKI 626
[180][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 74.3 bits (181), Expect = 5e-12
Identities = 60/213 (28%), Positives = 95/213 (44%), Gaps = 41/213 (19%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR--RAEAVAW-VKELKRGLAKWNK 172
+KV YN N+ VA LCNH RT+ +GH QM+KL R W +K++ L K
Sbjct: 675 EKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGERIKGLRYQKWRIKQMMLDLDPKIK 734
Query: 173 GGKGA--------------------------------------KAGAASSPPVEVTQYMP 238
KGA K A ++V + +
Sbjct: 735 KKKGAEFFELDPDLDEEWIKQHQAFLVEEQRQKIQKKFDKDNEKLRAEGEKEMKVKE-LE 793
Query: 239 VKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKE 418
+ E+ E + A K + + + + K ++ ++NL + ++R+ ++ + KE
Sbjct: 794 KRLEVAEELAAKFKKENKTKKVEAEG----KGATIEKYENNLAKLDQRIDTMSLQAQDKE 849
Query: 419 DLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
D + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 850 DNKEVALGTSKINYIDPRLTVVFSKKFSVPIEK 882
[181][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 74.3 bits (181), Expect = 5e-12
Identities = 59/216 (27%), Positives = 95/216 (43%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------R 115
+KV YN N+ VA LCNH RT+ + H QM+K+ R +
Sbjct: 642 EKVKAYNDANRRVAILCNHKRTVGASHANQMEKMSERIKGLRYQRWRLKQQMLDLDPNLK 701
Query: 116 AEAVA------------WVKELKRGLA---------KWNKGG-KGAKAGAASSPPVEVTQ 229
+ A W+KE + L K+ K K A G E+ +
Sbjct: 702 KKKGAKFFELDEDIDKEWIKEHQAFLVEEQRQKIRKKFEKDNEKLAAEGEKEMKASELEE 761
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ V E+ + + K + + P V +++++N+++ E+R+ + +
Sbjct: 762 RLQVATELEKKYNRENKTGKVEAEGKAPTV--------EKIEANIQKLEQRIETMELQAQ 813
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KED + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 814 DKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEK 849
[182][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 74.3 bits (181), Expect = 5e-12
Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 43/216 (19%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+K+A YN N+ VA LCNH +++ G +G K E +
Sbjct: 616 EKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAEDKIRALKYQRLKLRLQLFSLNPKIK 675
Query: 113 -------------------RAEAVAWVKELKRGLAKWNKGGKGAKA-GAASSPPVEVTQY 232
R EA K L+ KW+ + G E+
Sbjct: 676 KKHPELAEDESDVDDEFMERHEAELLEKALENAKKKWDTDNVKLEGDGKKKKTKGELD-- 733
Query: 233 MPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEM 412
E L + A+ K +++R A K+ + ++L + + R +ER+A ++
Sbjct: 734 -----ERLSEIKAEFKELKKERKAK--KIDPKRGATEEKLLAQIARIDERIATAKVQLQD 786
Query: 413 KEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ L+ VALGTSK NY+DPR+TVAW K +VP+EK+
Sbjct: 787 RDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKL 822
[183][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 74.3 bits (181), Expect = 5e-12
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ +GH+ QMQKL R
Sbjct: 687 EKVKLYNDCNREVAILCNHKRTVGAGHEQQMQKLGDRIKGLRYQQWRTKKMILDIDPTQK 746
Query: 113 RAEAVAW-----------VKELKRGLA---------KWNKGGKGAKAGAASS-PPVEVTQ 229
+ + AW +KE ++ L K+ K + KA P E+ +
Sbjct: 747 KKKGAAWFELDEDLDEEWIKEHQQFLIEEQRTKITKKFEKDNEKLKANKERPMPEKELKE 806
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ V E+ + K ++ + P V D+ +++ +ER+ L + E
Sbjct: 807 RLQVVKELEAKFKKENKTKKVEAEGRGPTV--------DKFIKAIEKLDERVKVLETQAE 858
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
++ + VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 859 DRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEK 894
[184][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 74.3 bits (181), Expect = 5e-12
Identities = 60/213 (28%), Positives = 95/213 (44%), Gaps = 41/213 (19%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR--RAEAVAW-VKELKRGLAKWNK 172
+KV YN N+ VA LCNH RT+ +GH QM+KL R W +K++ L K
Sbjct: 675 EKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGERIKGLRYQKWRIKQMMLDLDPKIK 734
Query: 173 GGKGA--------------------------------------KAGAASSPPVEVTQYMP 238
KGA K A ++V + +
Sbjct: 735 KKKGAEFFELDPDLDEEWIKQHQAFLVEEQRQKIQKKFDKDNEKLRAEGEKEMKVKE-LE 793
Query: 239 VKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKE 418
+ E+ E + A K + + + + K ++ ++NL + ++R+ ++ + KE
Sbjct: 794 KRLEVAEELAAKFKKENKTKKVEAEG----KGATIEKYENNLAKLDQRIDTMSLQAQDKE 849
Query: 419 DLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
D + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 850 DNKEVALGTSKINYIDPRLTVVFSKKFSVPIEK 882
[185][TOP]
>UniRef100_B3H4K2 Uncharacterized protein At4g26701.1 n=1 Tax=Arabidopsis thaliana
RepID=B3H4K2_ARATH
Length = 69
Score = 73.6 bits (179), Expect = 8e-12
Identities = 32/47 (68%), Positives = 40/47 (85%)
Frame = +2
Query: 380 RLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ K+ DM+ KEDL+TVALGTSK NY+DPRITVAWCK +E P+EKI
Sbjct: 2 KIEKMERDMQTKEDLKTVALGTSKINYMDPRITVAWCKRHEAPIEKI 48
[186][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 73.6 bits (179), Expect = 8e-12
Identities = 59/216 (27%), Positives = 94/216 (43%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAVA-------- 130
+KV YN N+ VA LCNH RT+ +GH+ QM+KL R R + +
Sbjct: 660 EKVKLYNDCNRKVAILCNHKRTVGAGHQAQMEKLGDRIKGLKYQQWRTKMMILDVDPKQK 719
Query: 131 -----------------WVKELKRGL---------AKWNKGGKGAKA-GAASSPPVEVTQ 229
W++E L K+ K + A G+ P E+ +
Sbjct: 720 KKLGADFFKLDEELDNEWIEEHLNFLYEEQRTKITKKFEKDNEKLVAEGSKKLPEKELKE 779
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ E+L + + K ++ + P V ++L K+ EER L +
Sbjct: 780 RLKAASELLTKLKKEHKTKKVEAEGRSPTV--------EKLLEGAKKIEERAKNLELQAQ 831
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
++ + VALGTSK NY+DPR+TV + + +VP+EK
Sbjct: 832 DRDGNKEVALGTSKLNYIDPRLTVVFSRKFDVPIEK 867
[187][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 73.6 bits (179), Expect = 8e-12
Identities = 59/208 (28%), Positives = 95/208 (45%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGL------- 157
+KV YN N+ VA LCNH RT+ H+ + K++ + E + W K LK+ +
Sbjct: 536 EKVMKYNAANRTVAILCNHQRTVSKAHQNSVGKIQEKIKE-MEWQKIRLKKMILVLDSSQ 594
Query: 158 -AKWNKGGKGAKAGAASSPPVEVTQYMP-------------------VKPEILESMTADE 277
AK K + + + + VTQ + K E+L E
Sbjct: 595 KAKNPKYFEELEDMTSEDQLMVVTQMIERQREQAKRKWTRDNEKRAMEKQELLTEEDLQE 654
Query: 278 KA-------QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
K +E + + +V + K ++LK +++ E R+ ++ KED V+
Sbjct: 655 KLSKIKASEEEYRHEIESGEVEVTKGASVEKLKVQIEKIENRILNTNFQLKDKEDNSEVS 714
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+TV + K VP+EK+
Sbjct: 715 LGTSKLNYIDPRLTVMFAKKFNVPIEKL 742
[188][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 72.8 bits (177), Expect = 1e-11
Identities = 57/216 (26%), Positives = 91/216 (42%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 654 EKVKAYNDANRKVAILCNHKRTVAASHANQMEKMSERIKGLRYQRWRLKQQMLDLEPSLK 713
Query: 113 -----------RAEAVAWVKELKRGLA---------KWNKGG-KGAKAGAASSPPVEVTQ 229
+ WVKE + L K+ K K A G E+
Sbjct: 714 KKKGAKYFEMDEDMDLEWVKEHQAFLVEEQRQKIQKKFEKDNEKLAAEGEKEMKATELES 773
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ V ++ + + K + + P V D++++ + + E+R+ + +
Sbjct: 774 RLQVAKDLEKKFNKENKTGKVEAEGKAPTV--------DKIEAAITKLEQRIETMELQAQ 825
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KE+ + VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 826 DKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEK 861
[189][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 72.4 bits (176), Expect = 2e-11
Identities = 54/166 (32%), Positives = 75/166 (45%), Gaps = 4/166 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 246 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 305
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 306 QGDGKSRSVL----------------------------EKKRRL---------------- 321
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWC
Sbjct: 322 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWC 364
[190][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 72.4 bits (176), Expect = 2e-11
Identities = 54/166 (32%), Positives = 75/166 (45%), Gaps = 4/166 (2%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---RAEAVAWVK-ELKRGLAKWNK 172
K+ YN+ N+VVA LCNH R PS + MQ L+T+ + E VA + EL+R A+
Sbjct: 246 KILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA 305
Query: 173 GGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQL 352
G G E+KR
Sbjct: 306 QGDGKSRSVL----------------------------EKKRRL---------------- 321
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWC
Sbjct: 322 ---LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWC 364
[191][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 72.4 bits (176), Expect = 2e-11
Identities = 58/218 (26%), Positives = 98/218 (44%), Gaps = 46/218 (21%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAVA-------- 130
+K+ YN N+ VA LCNH RT+ + H QM+KL R R + +
Sbjct: 681 EKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDRIKGLKYQEWRVKQMMLDLDPKIK 740
Query: 131 -----------------WVKE------------LKRGLAKWNKGGKGAKAGAASSPPVEV 223
W+KE +K+ K N+ K A G P E+
Sbjct: 741 KKKGPAFFELDESLDQEWIKEHQDYLVEEQRQKIKKKFEKDNE--KRAAEGEKEMKPKEL 798
Query: 224 TQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSD 403
+ + E+ +++ A K + + + + K + ++L++ L + +R+ ++
Sbjct: 799 EERL----EVAKALEAKFKRENKTKKVEAEG----KGVTIEKLENQLLKLSQRIENMSLQ 850
Query: 404 MEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
E +E+ + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 851 AEDRENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEK 888
[192][TOP]
>UniRef100_Q3TSR2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3TSR2_MOUSE
Length = 144
Score = 72.0 bits (175), Expect = 2e-11
Identities = 52/164 (31%), Positives = 75/164 (45%)
Frame = +2
Query: 29 NKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASS 208
N+ VA LCNH R P + M L+++ + K LA + K AKA A
Sbjct: 2 NRAVAILCNHQRAPPKTFEKSMMNLQSK-------IDAKKDQLADARRDLKSAKADA--- 51
Query: 209 PPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLA 388
++++ + + +K+A ++R EE+L
Sbjct: 52 -------------KVMKDAKTKKVVESKKKA--------------------VQRLEEQLM 78
Query: 389 KLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 79 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 122
[193][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 72.0 bits (175), Expect = 2e-11
Identities = 59/216 (27%), Positives = 97/216 (44%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAV--------- 127
+K+ YN N+ VA LCNH RT+ +GH+ QM+KL R R + +
Sbjct: 675 EKIKLYNDCNREVAILCNHKRTVGAGHEAQMEKLGDRIKGLKYQKWRTKMMMLDLDPKLK 734
Query: 128 ----------------AWVKELKRGLA---------KWNKGGKGAKAG-AASSPPVEVTQ 229
AWV+E ++ LA K+ K + +A A P E+ +
Sbjct: 735 KKKGAEFFELDSDLDQAWVEEHQQFLAKELQEKIEKKFAKDNEKLEADKQAKLPAKELKE 794
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ E+ + K ++ + P V ++L + +++ +ER+ L
Sbjct: 795 RLKAVAELEAKFKKENKTKKVEAEGKGPSV--------EKLTTAVEKLDERIRTLEMQSA 846
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+E + VALGTSK NY+DPR+TV + +VP+EK
Sbjct: 847 DREGNKEVALGTSKINYIDPRLTVVFSNKFQVPIEK 882
[194][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 71.2 bits (173), Expect = 4e-11
Identities = 55/177 (31%), Positives = 80/177 (45%), Gaps = 4/177 (2%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRRAEAVAWVKELKRGLAKWN 169
+K+ YN+ N+ VA LCNH R P M K+++R+ + KELK+
Sbjct: 380 EKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAKIDSRKEQLDLAKKELKQAK---- 435
Query: 170 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQ 349
K AK + + V V E+K+ A
Sbjct: 436 ---KEAKGSSDNKLLVVV---------------------EKKKKA--------------- 456
Query: 350 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++R EE+L K+ +E+ + +AL TSK NYLDPRI+VAWCK EVP++KI
Sbjct: 457 ----VQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKI 509
[195][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 71.2 bits (173), Expect = 4e-11
Identities = 55/177 (31%), Positives = 80/177 (45%), Gaps = 4/177 (2%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ----KLETRRAEAVAWVKELKRGLAKWN 169
+K+ YN+ N+ VA LCNH R P M K+++R+ + KELK+
Sbjct: 458 EKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAKIDSRKEQLDLAKKELKQAK---- 513
Query: 170 KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQ 349
K AK + + V V E+K+ A
Sbjct: 514 ---KEAKGSSDNKLLVVV---------------------EKKKKA--------------- 534
Query: 350 LKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++R EE+L K+ +E+ + +AL TSK NYLDPRI+VAWCK EVP++KI
Sbjct: 535 ----VQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKI 587
[196][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 71.2 bits (173), Expect = 4e-11
Identities = 56/168 (33%), Positives = 72/168 (42%)
Frame = +2
Query: 17 YNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAG 196
YN+ N+ VA LCNH R P + M A+ K LA K K AKA
Sbjct: 616 YNRANRAVAILCNHQRAPPKTFEKSMMNQSKIDAK--------KDQLADARKDLKSAKAD 667
Query: 197 AASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAE 376
A + +K +K+A ++R E
Sbjct: 668 AKVMKDAKT-----------------KKVVSKKKA--------------------VQRLE 690
Query: 377 ERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
E+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 691 EQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 738
[197][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 71.2 bits (173), Expect = 4e-11
Identities = 49/168 (29%), Positives = 79/168 (47%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
D + F+N N+ VA LCNH R++P H M K++ + ++E K+ L K
Sbjct: 664 DLINFFNNANREVAILCNHQRSIPKQHDTTMSKIKKQIEIYNEDMQEYKKYLQYLKKNNN 723
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
+ S K L+ K +E +M+ + K
Sbjct: 724 EKEFTFVS------------KVVTLDGSLRPNKVKE--------------NMKEESCKKK 757
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEV 505
L +++ L + M++++D +T+ALGTSK NY+DPRITVA+CK E+
Sbjct: 758 LIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQFEI 805
[198][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 71.2 bits (173), Expect = 4e-11
Identities = 61/209 (29%), Positives = 91/209 (43%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 768 EKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSERIKGLRYQRWRLKQQMLDLDPSLK 827
Query: 113 -----------RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
++ WVKE + L + + K K + + +K LE
Sbjct: 828 KKKGAKFFEMDEDISMEWVKEHQAFLLEEQRQ-KIKKKFEKENEKLAAEGEKEMKASELE 886
Query: 260 SMTADEKAQERK--RAADLPKVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
K E K R KV + KS ++L++ + + E+R+ + + KED +
Sbjct: 887 HRLEAVKEMENKFMRENKTGKVEVEGKSPSVEKLEAAITKLEQRIETMELQAQDKEDNKE 946
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 947 VALGTSKINYIDPRLTVVFSKKFNVPIEK 975
[199][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 70.9 bits (172), Expect = 5e-11
Identities = 57/173 (32%), Positives = 80/173 (46%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+K+ YN+ N+ VA LCNH R P M L+++ + K LA G K
Sbjct: 480 EKLLSYNRANRAVAILCNHQRAPPKTFDQSMATLQSK-------IDARKEQLALAKSGLK 532
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSN 361
AK A + E L+++ ERK+AA
Sbjct: 533 QAKKEAKAKGSSEFK---------LQTLV------ERKKAA------------------- 558
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+KR E+ L K+ +E+ + +ALGTSK NYLDPRI+VAWCK +PV+KI
Sbjct: 559 VKRCEQ-LLKMEIQATDREENKQIALGTSKLNYLDPRISVAWCKNMGLPVDKI 610
[200][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 70.9 bits (172), Expect = 5e-11
Identities = 61/209 (29%), Positives = 99/209 (47%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKE-LKRGLAKW---- 166
+K+ YN N+ VA LCNH RT+ +GH + K + R E W KE LK+G+ +
Sbjct: 488 EKLLKYNAANRTVAILCNHQRTVTAGHAKSVAK-SSDRIEEFKWQKERLKKGILQIEPDR 546
Query: 167 -----------NKGGKGAKAGAASSP-PVEVTQYM----------------PVKPEILES 262
N K +A E+ +Y P+ E L+
Sbjct: 547 IKDTPNYFEDINSIDKEIEAKIHERIIEREIQKYHNKFKRENDKRKFEGEEPLPEETLKE 606
Query: 263 MTADEKAQERKRAADLPK--VPLLKSMRG-DQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ K +++ A +L V L SM ++L+ ++R ++R++ ++ +E V
Sbjct: 607 WLDNVKQLKQQYAEELATGIVQLKASMNSVEKLEKAIERLDQRISTSQVQLQDREANSEV 666
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+LGTSK NY+DPR++V +CK VP+EKI
Sbjct: 667 SLGTSKINYIDPRLSVVFCKKYGVPIEKI 695
[201][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 70.9 bits (172), Expect = 5e-11
Identities = 60/209 (28%), Positives = 92/209 (44%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 656 EKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSERIKGLRYQRWRLKQQMLDLDPSLK 715
Query: 113 -----------RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
++ WVKE + L + + K K + + +K LE
Sbjct: 716 KKKGAKFFEMDEDISMEWVKEHQAYLLEEQRQ-KIKKKFEKENEKLAAEGEKEMKASELE 774
Query: 260 SMTADEKAQERK--RAADLPKVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
S K E K + KV + KS ++L++ + + E+R+ + + KE+ +
Sbjct: 775 SRLEAVKEMENKFKKENKTGKVDVEGKSSSVEKLEAAITKLEQRIETMELQAQDKEENKE 834
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 835 VALGTSKINYIDPRLTVVFSKKFNVPIEK 863
[202][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 70.1 bits (170), Expect = 9e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H + K+ +
Sbjct: 657 EKVKAYNDANREVAILCNHKRTVAATHGASIDKMNEKIKGLRYQVWRTKMMMIDVDPKIK 716
Query: 113 ---------RAEAV--AWVK--------ELKRGLAKW--NKGGKGAKAGAASSPPVEVTQ 229
R E + WVK E+++ + K K A G P E+T
Sbjct: 717 KKKGAEYFERPEDLDAEWVKQHQDAEVDEMRQKITKKFEKDNEKLAAEGEKEMKPKELTD 776
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ E+ + K + + P V ++L++N+ + +R+ + ME
Sbjct: 777 RLEKVEELASKYKKENKTGKVEAEGKGPTV--------EKLEANIDKINQRIENMRIQME 828
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KE + VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 829 DKEGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEK 864
[203][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 70.1 bits (170), Expect = 9e-11
Identities = 58/208 (27%), Positives = 94/208 (45%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAVA-------- 130
+K+ YN N+ VA LCNH RT+ + H QM+KL R R + +
Sbjct: 679 EKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDRIKGLRYQEWRVKQMMLDLDPKIK 738
Query: 131 -----------------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
W+KE + L + + K + V + E+ E
Sbjct: 739 KKKGSAFFELDESLDHEWIKEHQAYLVEEQRQKIKKKFEKDNQKRVAEGEREMKAKELEE 798
Query: 260 SMTADEKAQER-KRAADLPKVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A ++ + + KR KV K + ++L++ L + +R+ ++ E KE+ + V
Sbjct: 799 RLEAAKELEAKFKRENKTKKVEAEGKGITIEKLENQLLKLSQRIENMSLQAEDKENNKEV 858
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + K VP+EK
Sbjct: 859 ALGTSKINYIDPRLTVVFSKKFNVPIEK 886
[204][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 70.1 bits (170), Expect = 9e-11
Identities = 56/208 (26%), Positives = 94/208 (45%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 675 EKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGDRIKGLKYQQWRLKQMMLDLDPKLK 734
Query: 113 RAEAVA-----------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
+ + A W+KE + L + + K + V + E+ E
Sbjct: 735 KKKGAAYFELDESLDQEWIKEHQAFLVEEQRQKIKKKFEKDNEKRVAEGEKEMKAKELEE 794
Query: 260 SMTADEKAQERKRAADLPK--VPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A + + + + + K VP K + ++L++ L + +R+ ++ E KE+ + V
Sbjct: 795 RLEAANELEAKFKKENKSKKVVPEGKGVTVEKLENQLLKLGQRIENMSLQAEDKENNKEV 854
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + + VP+EK
Sbjct: 855 ALGTSKINYIDPRLTVVFSRKFNVPMEK 882
[205][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 70.1 bits (170), Expect = 9e-11
Identities = 58/208 (27%), Positives = 94/208 (45%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAVA-------- 130
+K+ YN N+ VA LCNH RT+ + H QM+KL R R + +
Sbjct: 679 EKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGDRIKGLRYQEWRVKQMMLDLDPKIK 738
Query: 131 -----------------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
W+KE + L + + K + V + E+ E
Sbjct: 739 KKKGSAFFELDESLDHEWIKEHQAYLVEEQRQKIKKKFEKDNQKRVAEGEREMKAKELEE 798
Query: 260 SMTADEKAQER-KRAADLPKVPLL-KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A ++ + + KR KV K + ++L++ L + +R+ ++ E KE+ + V
Sbjct: 799 RLEAAKELEAKFKRENKTKKVEAEGKGITIEKLENQLLKLSQRIENMSLQAEDKENNKEV 858
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + K VP+EK
Sbjct: 859 ALGTSKINYIDPRLTVVFSKKFNVPIEK 886
[206][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 69.7 bits (169), Expect = 1e-10
Identities = 57/206 (27%), Positives = 97/206 (47%), Gaps = 33/206 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK--------ELKRGL 157
+K+ +N N+ VA LCNH +T+ H + K+E R E V W K +L+ L
Sbjct: 534 EKLVKFNAANRAVAILCNHQKTVSKTHGESVGKIEDRINEVV-WQKWRHKRMLLDLEPKL 592
Query: 158 AK--------WNKGGKGAKAGAASSPPVEVTQYMPVKPE------ILESMTADEKAQERK 295
K ++ K K A+ + ++ K E + E K++
Sbjct: 593 LKKEPKLFEDLDELSKEEKTACANRLLEKDSERWTKKFERDNEKLVAEKQKPKPKSELNA 652
Query: 296 RAADLPKV--PLLKSMRG---------DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALG 442
+ DL LK ++ ++L++ +++ E R+ + ++ KED +VALG
Sbjct: 653 KLKDLADTNKQYLKEIKSNKVEGKGTVEKLRAQVEKLETRVTTMRMQLKDKEDNSSVALG 712
Query: 443 TSKQNYLDPRITVAWCKANEVPVEKI 520
TSK NY+DPR+TV + K +VP+EK+
Sbjct: 713 TSKMNYIDPRLTVKFSKKYDVPIEKL 738
[207][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 69.7 bits (169), Expect = 1e-10
Identities = 54/208 (25%), Positives = 97/208 (46%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ +GH M+K+ R
Sbjct: 634 EKVKAYNDANRKVAILCNHKRTVTAGHANAMEKMGERIKGLRYQKWRLKQQMLDLDPTLK 693
Query: 113 RAEAVA-----------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
+ + A W++E + L + + K + V + E+ E
Sbjct: 694 KKKGAAFFEIDEDLDKEWIEEHQAFLIEEQRNKINKKFEKDNEKRVADGEKEMKVSELEE 753
Query: 260 SMTADEKAQER-KRAADLPKVPL-LKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A ++ +++ K+ KV + ++L++++ + ++R+ ++ + KED + V
Sbjct: 754 RLQAVKELEKKFKKENKTGKVEAEARGATVEKLENSINKIDQRVETMSVQAQDKEDNKEV 813
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 814 ALGTSKINYIDPRLTVVFSKKYDVPIEK 841
[208][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 69.3 bits (168), Expect = 1e-10
Identities = 57/216 (26%), Positives = 92/216 (42%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEA------------------- 124
+KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 651 EKVKAYNDANRQVAILCNHKRTVTASHANQMEKMGERIKGLRYQRWRLKQQMLDLEPNLK 710
Query: 125 ---------------VAWVKELKRGLA---------KWNKGG-KGAKAGAASSPPVEVTQ 229
+ W+KE + L K++K K A G E+
Sbjct: 711 KKKGAKFFEMDEDIDMEWIKEHQAFLLEEQRQKIQKKFDKDNEKLAAEGEKEMKAKELEN 770
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ V ++ + + K + + P V ++L++ +++ E+R+ + +
Sbjct: 771 RLEVVKDMEKKFNKENKTGKVEAEGKGPTV--------EKLENAIQKLEQRIETMELQAQ 822
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KED + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 823 DKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEK 858
[209][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 69.3 bits (168), Expect = 1e-10
Identities = 57/216 (26%), Positives = 92/216 (42%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEA------------------- 124
+KV YN N+ VA LCNH RT+ + H QM+K+ R
Sbjct: 651 EKVKAYNDANRQVAILCNHKRTVTASHANQMEKMGERIKGLRYQRWRLKQQMLDLEPNLK 710
Query: 125 ---------------VAWVKELKRGLA---------KWNKGG-KGAKAGAASSPPVEVTQ 229
+ W+KE + L K++K K A G E+
Sbjct: 711 KKKGAKFFEMDEDIDMEWIKEHQAFLLEEQRQKIQKKFDKDNEKLAAEGEKEMKAKELEN 770
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ V ++ + + K + + P V ++L++ +++ E+R+ + +
Sbjct: 771 RLEVVKDMEKKFNKENKTGKVEAEGKGPTV--------EKLENAIQKLEQRIETMELQAQ 822
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KED + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 823 DKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEK 858
[210][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 69.3 bits (168), Expect = 1e-10
Identities = 57/209 (27%), Positives = 100/209 (47%), Gaps = 36/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAK----- 163
+K+ YN N+ VA LCNH R++ GH ++K + E + W K LKR + +
Sbjct: 570 EKMLRYNAANRTVAILCNHQRSVGKGHAEAVRKAN-EKIEELEWQKIRLKRAILQLEPKE 628
Query: 164 WNKGGKG-AKAGAASSPPVEVTQYMPVKPEIL-----------------ESMTADEKAQE 289
K K A+ G + E ++ EI E + +E+ +E
Sbjct: 629 MKKRPKFFAEIGDLTKEDEESIHKRIIEREIERCHRKFQRENDKRKFDNEELIKEEELKE 688
Query: 290 -RKRAADLPKVPLLKSMRGD-----------QLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ ++ K L+ G+ +L+ N+++ E+R+ + ++ KE+ V
Sbjct: 689 WLDKVSETEKKYSLEVETGEVEIKSTLNTVEKLEKNIEKLEQRIQTSSIQLKDKEENSQV 748
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+LGTSK NY+DPR++V +CK ++P+EKI
Sbjct: 749 SLGTSKINYIDPRLSVVFCKKFDIPIEKI 777
[211][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 68.9 bits (167), Expect = 2e-10
Identities = 55/208 (26%), Positives = 94/208 (45%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+K+ YN N+ VA LCNH RT+ + H QM+KL R
Sbjct: 670 EKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGDRIKGLKYQQWRLKQMMLDLDPKLK 729
Query: 113 RAEAVA-----------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
+ + A W++E + L + + K + V + E+ E
Sbjct: 730 KKKGAAYFELDESLDQEWIREHQAFLVEEQRQKIKKKFEKDNEKRVAEGEKEMKAKELEE 789
Query: 260 SMTADEKAQERKRAADLPK--VPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A + + + + + K VP K + ++L++ L + +R+ ++ E KE+ + V
Sbjct: 790 RLEAANELEAKFKKENKSKKVVPEGKGVTVEKLENQLLKLGQRIENMSLQAEDKENNKEV 849
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + + VP+EK
Sbjct: 850 ALGTSKINYIDPRLTVVFSRKFNVPMEK 877
[212][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 68.9 bits (167), Expect = 2e-10
Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 37/209 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR---------RAEAVA-------- 130
+KV YN N+ VA LCNH R++ + H QM+KL R R + +
Sbjct: 674 EKVKIYNDCNRQVAILCNHKRSVGASHDAQMKKLGDRILGLKYQQWRTKMMMIDLDPKLK 733
Query: 131 -----------------WVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 259
WVKE + L + + K + V + + E+ E
Sbjct: 734 KKKGAQFFERIPELTDEWVKEHQAFLVEEKRAAITKKFEKDNEKAVANGEKKMPEKELKE 793
Query: 260 SMTADEKAQERKRAADLPKVPLLKSMRG---DQLKSNLKRAEERLAKLTSDMEMKEDLQT 430
+ A + + + K L + RG ++L+ +K+ +ER+ + ++ +
Sbjct: 794 RLKAASEMDAMYKKENKTKKVLAEG-RGVTVEKLEQQVKKLDERIRTMELQAADRDGNKE 852
Query: 431 VALGTSKQNYLDPRITVAWCKANEVPVEK 517
VALGTSK NY+DPR+TV +C VP+EK
Sbjct: 853 VALGTSKINYIDPRLTVVFCNKMNVPIEK 881
[213][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 68.6 bits (166), Expect = 3e-10
Identities = 58/208 (27%), Positives = 91/208 (43%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAKWNKGG 178
+KV +N N+ VA LCNH RT+ H +QK+ + E + W K K+ + +
Sbjct: 561 EKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHDKLKE-LEWHKIRTKKMILQLEPNL 619
Query: 179 KG---------------------------AKAGAASSPPVEVTQYMPVKPEILESMTADE 277
K A+ A E + +L +E
Sbjct: 620 KTKDPDYFEELDDLSKEDTEHIHRALIERAREAARKRFQRENDKLKIEDKPLLTEKDLEE 679
Query: 278 KAQ-----ERKRAADLP--KVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
K + E++ A +L K + KS+ ++LKS + R+ T ++ KED V+
Sbjct: 680 KMEKVNELEKEYAEELKTGKPQIKKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVS 739
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+TV + K VP+EK+
Sbjct: 740 LGTSKMNYIDPRLTVMFSKKFNVPIEKL 767
[214][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 68.6 bits (166), Expect = 3e-10
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 39/211 (18%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH RT+ + H QM+K+ R LK+ + + K
Sbjct: 641 EKVKAYNDANRKVAILCNHKRTVGAAHAHQMEKMSERIKGQRYQKWRLKQMMLDLDPSLK 700
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL----KSMRGDQ 349
K GA E +K ++ +E+AQ+ K+ + LL K M+ +
Sbjct: 701 -KKKGAQFFELDEDIDKEWIKEH--QAFLIEEQAQKIKKKFEKDNEKLLAEGEKEMKASE 757
Query: 350 LKSNLKRAEE-------------------------------RLAKLTSDMEM----KEDL 424
L++ L+ +E +L + +ME+ KED
Sbjct: 758 LETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQQRIENMELQAQDKEDN 817
Query: 425 QTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+ VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 818 KEVALGTSKINYIDPRLTVVFSKKFKVPIEK 848
[215][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 68.6 bits (166), Expect = 3e-10
Identities = 58/208 (27%), Positives = 91/208 (43%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK-ELKRGLAKWNKGG 178
+KV +N N+ VA LCNH RT+ H +QK+ + E + W K K+ + +
Sbjct: 561 EKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHDKLKE-LEWHKIRTKKMILQLEPNL 619
Query: 179 KG---------------------------AKAGAASSPPVEVTQYMPVKPEILESMTADE 277
K A+ A E + +L +E
Sbjct: 620 KTKDPDYFEELDDLSKEDTEHIHRALIERAREAARKRFQRENDKLKIEDKPLLTEKDLEE 679
Query: 278 KAQ-----ERKRAADLP--KVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
K + E++ A +L K + KS+ ++LKS + R+ T ++ KED V+
Sbjct: 680 KMEKVNELEKEYAEELKTGKPQIKKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVS 739
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+TV + K VP+EK+
Sbjct: 740 LGTSKMNYIDPRLTVMFSKKFNVPIEKL 767
[216][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 68.6 bits (166), Expect = 3e-10
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 39/211 (18%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH RT+ + H QM+K+ R LK+ + + K
Sbjct: 641 EKVKAYNDANRKVAILCNHKRTVGAAHAHQMEKMSERIKGQRYQKWRLKQMMLDLDPSLK 700
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL----KSMRGDQ 349
K GA E +K ++ +E+AQ+ K+ + LL K M+ +
Sbjct: 701 -KKKGAQFFELDEDIDKEWIKEH--QAFLIEEQAQKIKKKFEKDNEKLLAEGEKEMKASE 757
Query: 350 LKSNLKRAEE-------------------------------RLAKLTSDMEM----KEDL 424
L++ L+ +E +L + +ME+ KED
Sbjct: 758 LETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQQRIENMELQAQDKEDN 817
Query: 425 QTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+ VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 818 KEVALGTSKINYIDPRLTVVFSKKFKVPIEK 848
[217][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 68.6 bits (166), Expect = 3e-10
Identities = 56/208 (26%), Positives = 97/208 (46%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE--TRRAEAVAW-VKELKRGLAKWNK 172
+K+ YN N+ VA LCNH RT+ + H+ ++K++ + + W +K++ L K
Sbjct: 679 EKIKLYNDCNRKVAILCNHKRTVGASHEAAIEKMDDAVKGLKYQKWRLKQMILDLDPKQK 738
Query: 173 GGKGA-----------------KAGAASSPPVEVTQYMPVKPEILES-----MTADEKAQ 286
KGA +A + +++ + + E L S M E +
Sbjct: 739 KKKGADWFALDEELDEAWIQEHQAFLVAQERIKIEKKFAKENEKLVSEGQKEMKTKELNE 798
Query: 287 ERKRAADLPK-----------VPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
+ A DL K K ++ ++N+ + +ER+A + E +E + V
Sbjct: 799 RLQAATDLEKKFKKENKSKKVEAEGKGSSVEKFEANITKIDERIANMLLKREDREGNKEV 858
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + + +VP+EK
Sbjct: 859 ALGTSKINYIDPRLTVVFSQKFDVPIEK 886
[218][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 68.2 bits (165), Expect = 3e-10
Identities = 54/172 (31%), Positives = 78/172 (45%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P M L+++ + KE
Sbjct: 353 KILSYNRANRAVAILCNHQRAPPKTFDQSMANLKSK----IDAKKE-------------- 394
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
Q + K E+ E+ +K + K + L KV K K +
Sbjct: 395 --------------QILLAKKELKEA----KKEAKEKESEKLNKVVESK-------KRGV 429
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+RAEE+L ++ +E+ + +AL TSK NYLDPRI+VAWCK V +EKI
Sbjct: 430 QRAEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKI 481
[219][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 68.2 bits (165), Expect = 3e-10
Identities = 56/208 (26%), Positives = 96/208 (46%), Gaps = 36/208 (17%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE--TRRAEAVAW-VKELKRGLAKWNK 172
+K+ YN N+ VA LCNH RT+ + H+ ++K++ + + W +K++ + K
Sbjct: 680 EKIKLYNDCNRKVAILCNHKRTVGASHEAAIEKMDDAVKGLKYQKWRLKQMILDIDPKQK 739
Query: 173 GGKGA-----------------KAGAASSPPVEVTQYMPVKPEILES-----MTADEKAQ 286
KGA +A + +++ + + E L S M E +
Sbjct: 740 KKKGADWFALDEELDESWIQEHQAFLVAQERIKIEKKFAKENEKLVSEGQKEMKTKELNE 799
Query: 287 ERKRAADLPKVPLL-----------KSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTV 433
A DL K K D+ ++N+ + +ER+A + E +E + V
Sbjct: 800 RLHAATDLEKKFKKENKTKKVEAEGKGPSVDKFEANITKIDERIANMLLKREDREGNKEV 859
Query: 434 ALGTSKQNYLDPRITVAWCKANEVPVEK 517
ALGTSK NY+DPR+TV + + +VP+EK
Sbjct: 860 ALGTSKINYIDPRLTVVFSQKFDVPIEK 887
[220][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 67.8 bits (164), Expect = 4e-10
Identities = 57/216 (26%), Positives = 93/216 (43%), Gaps = 44/216 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H ++K+ R
Sbjct: 675 EKVKAYNDANREVAILCNHKRTVAASHATSIEKMNERINGLRYQAWRTKMMMIDVDPKIK 734
Query: 113 ---------RAEAV--AWVKE---------LKRGLAKWNKGGKGAKA-GAASSPPVEVTQ 229
R E + WVK+ ++ + K+ K + KA G E+ +
Sbjct: 735 KKKGAEYFERPEDLDDEWVKQHQDAEVEEMRQKIIKKFEKDNEKLKADGEKELKQKELNE 794
Query: 230 YMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 409
+ E+ + K + + P V ++L++N+++ +R+ + ME
Sbjct: 795 RLEKAEELAAKYKKENKTGKIEAEGKGPTV--------EKLEANVEKIVQRIENMKIQME 846
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
KE + VALGTSK NY+DPR+TV + K VP+EK
Sbjct: 847 DKEGNKEVALGTSKINYIDPRLTVVFSKKFGVPIEK 882
[221][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 65.9 bits (159), Expect = 2e-09
Identities = 31/59 (52%), Positives = 43/59 (72%)
Frame = +2
Query: 344 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
D+ L+R +E+L KL +++ +T+ALGTSK NYLDPRI+VAWCK + VP+EKI
Sbjct: 910 DKKGKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKI 968
[222][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 65.1 bits (157), Expect = 3e-09
Identities = 55/215 (25%), Positives = 93/215 (43%), Gaps = 43/215 (20%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR----------------------- 112
+KV YN N+ VA LCNH RT+ + H+ QM KL R
Sbjct: 678 EKVKLYNDCNREVAILCNHKRTVGASHEQQMAKLGDRIKGLRYQQWRTKMMILDVDSSYK 737
Query: 113 RAEAVAW-----------VKELKRGLA---------KWNKGGKGAKAGAASSPPVEVTQY 232
+ + AW +KE ++ L K+ K + KA P +
Sbjct: 738 KKKGTAWFEKDEELNDEWIKEHQQFLLEEQRTKVQKKFEKDNEKRKADKERPLP---EKE 794
Query: 233 MPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEM 412
+ + ++++ M A K + + + + + D+ + + +ER+ L +
Sbjct: 795 LKERLQVVKEMEAKFKKENKSKKVEAEG----RGATVDKFLKAVDKFDERIKTLELQAQD 850
Query: 413 KEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
++ + VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 851 RDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEK 885
[223][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 65.1 bits (157), Expect = 3e-09
Identities = 53/172 (30%), Positives = 77/172 (44%)
Frame = +2
Query: 5 KVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGKG 184
K+ YN+ N+ VA LCNH R P M L+++ + KE
Sbjct: 353 KILSYNRANRAVAILCNHQRAPPKTFDQSMANLKSK----IDAKKE-------------- 394
Query: 185 AKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNL 364
Q + K E+ E+ +K + K + L KV K K +
Sbjct: 395 --------------QILLAKKELKEA----KKEAKEKDSEKLNKVVESK-------KRAV 429
Query: 365 KRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+R EE+L ++ +E+ + +AL TSK NYLDPRI+VAWCK V +EKI
Sbjct: 430 QRTEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKI 481
[224][TOP]
>UniRef100_Q6LBJ1 Topoisomerase I (Fragment) n=1 Tax=Mus musculus RepID=Q6LBJ1_MOUSE
Length = 115
Score = 65.1 bits (157), Expect = 3e-09
Identities = 32/56 (57%), Positives = 40/56 (71%)
Frame = +2
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K ++R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK VP+EKI
Sbjct: 38 KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKI 93
[225][TOP]
>UniRef100_Q8TBP3 TOP1MT protein (Fragment) n=1 Tax=Homo sapiens RepID=Q8TBP3_HUMAN
Length = 101
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/53 (58%), Positives = 41/53 (77%)
Frame = +2
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L++ +E+LA+L+ KE+ + VALGTSK NYLDPRI++AWCK VPVEKI
Sbjct: 27 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKI 79
[226][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 65.1 bits (157), Expect = 3e-09
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 34/207 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KVA +N N+ VA LCNH RT+ H +Q++ + E + LK+ + + K
Sbjct: 552 EKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDKLKEFMWQKIRLKKMILQLEPKLK 611
Query: 182 GA------KAGAASSPPVEVTQYMPVK----------------------PEILESMTAD- 274
+ +E + +K P + ES D
Sbjct: 612 KKDPKYFEEIDDLIKEDIEHIHHTIIKRQREQAKKKLERDNEKLKLEGKPLLTESDIKDK 671
Query: 275 -----EKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVAL 439
E +E ++ K + K+ ++LK ++ E ++ ++ ++ KED V+L
Sbjct: 672 LDKIDELEKEYQKELKTGKPIVTKNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSL 731
Query: 440 GTSKQNYLDPRITVAWCKANEVPVEKI 520
GTSK NY+DPR+ V + K +VP+EK+
Sbjct: 732 GTSKMNYIDPRLIVMFSKKFDVPIEKL 758
[227][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 65.1 bits (157), Expect = 3e-09
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 34/207 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KVA +N N+ VA LCNH RT+ H +Q++ + E + LK+ + + K
Sbjct: 552 EKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDKLKEFMWQKIRLKKMILQLEPKLK 611
Query: 182 GA------KAGAASSPPVEVTQYMPVK----------------------PEILESMTAD- 274
+ +E + +K P + ES D
Sbjct: 612 KKDPKYFEEIDDLIKEDIEHIHHTIIKRQREQAKKKLERDNEKLKLEGKPLLTESDIKDK 671
Query: 275 -----EKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVAL 439
E +E ++ K + K+ ++LK ++ E ++ ++ ++ KED V+L
Sbjct: 672 LDKIDELEKEYQKELKTGKPIVTKNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSL 731
Query: 440 GTSKQNYLDPRITVAWCKANEVPVEKI 520
GTSK NY+DPR+ V + K +VP+EK+
Sbjct: 732 GTSKMNYIDPRLIVMFSKKFDVPIEKL 758
[228][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 65.1 bits (157), Expect = 3e-09
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 39/211 (18%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVKELKRGLAKWNKGGK 181
+KV YN N+ VA LCNH RT+ + + QM+K+ R LK+ + + K
Sbjct: 641 EKVKAYNDANRKVAILCNHKRTVGAVTRDQMEKMSERIKGQRYQKWRLKQMMLDLDPSLK 700
Query: 182 GAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLL----KSMRGDQ 349
K GA E +K ++ +E+AQ+ K+ + LL K M+ +
Sbjct: 701 -KKKGAQFFELDEDIDKEWIKEH--QAFLIEEQAQKIKKKFEKDNEKLLAEGEKEMKASE 757
Query: 350 LKSNLKRAEE-------------------------------RLAKLTSDMEM----KEDL 424
L++ L+ +E +L + +ME+ KED
Sbjct: 758 LETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQQRIENMELQAQDKEDN 817
Query: 425 QTVALGTSKQNYLDPRITVAWCKANEVPVEK 517
+ VALGTSK NY+DPR+TV + K +VP+EK
Sbjct: 818 KEVALGTSKINYIDPRLTVVFSKKFKVPIEK 848
[229][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6JVY3_SCHJY
Length = 654
Score = 65.1 bits (157), Expect = 3e-09
Identities = 34/97 (35%), Positives = 58/97 (59%), Gaps = 10/97 (10%)
Frame = +2
Query: 260 SMTADEKAQERKRAADLPKVPLLKSMR----------GDQLKSNLKRAEERLAKLTSDME 409
S+ D + +ER +AAD K L + +R +QL+ L + +ER+ +++ +
Sbjct: 537 SVMPDSELEERLKAADELKAKLDEELRTGAVEAGRSSNEQLEKRLIKMDERIKVMSNSII 596
Query: 410 MKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K++ +T ALGTSK NY+DPR+T + CK +P+EK+
Sbjct: 597 DKDENKTTALGTSKINYIDPRLTFSLCKRENIPIEKL 633
[230][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 65.1 bits (157), Expect = 3e-09
Identities = 54/208 (25%), Positives = 94/208 (45%), Gaps = 35/208 (16%)
Frame = +2
Query: 2 DKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETRRAEAVAWVK------------EL 145
+KVA +N N+ VA LCNH RT+ H +Q++ + + W K +L
Sbjct: 550 EKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRIND-KLKKFMWQKIRLKKMILQLEPKL 608
Query: 146 KRGLAKW--------------------NKGGKGAKAGAASSPPVEVTQYMPVKPE--ILE 259
K+ +K+ + + AK + P+ E I +
Sbjct: 609 KKKDSKYFEEIDDLIKEDIEHIHHTIIKRQREQAKKKLERDNEKLKLEGKPLLTESDIKD 668
Query: 260 SMTA-DEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVA 436
+ DE +E ++ K + K+ ++LK ++ E R+ ++ ++ KED V+
Sbjct: 669 KLDKIDELEKEYQKELKTGKPIVTKNATVEKLKQQIETLENRILNVSIQLKDKEDNSEVS 728
Query: 437 LGTSKQNYLDPRITVAWCKANEVPVEKI 520
LGTSK NY+DPR+ V + K +VP+EK+
Sbjct: 729 LGTSKMNYIDPRLIVMFSKKFDVPIEKL 756
[231][TOP]
>UniRef100_A4HS02 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania infantum
RepID=A4HS02_LEIIN
Length = 262
Score = 63.5 bits (153), Expect = 8e-09
Identities = 35/82 (42%), Positives = 53/82 (64%), Gaps = 2/82 (2%)
Frame = +2
Query: 281 AQERKRAADL--PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQ 454
AQE + L P+ P+++S D K+ L+R ERL + + + +K+D + V+LGTSK
Sbjct: 162 AQEEEEVPTLVPPRPPVVRSFPNDIGKA-LERYRERLNREENIIRIKDDNKAVSLGTSKI 220
Query: 455 NYLDPRITVAWCKANEVPVEKI 520
NY+DPRI +W KA +VP+ KI
Sbjct: 221 NYIDPRIICSWAKAQDVPINKI 242
[232][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/65 (49%), Positives = 45/65 (69%), Gaps = 1/65 (1%)
Frame = +2
Query: 329 KSMRGDQLKSN-LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEV 505
KS + ++K ++R EE+L KL +E+ + +ALGTSK NYLDPRI+VAWCK +
Sbjct: 704 KSKKAVEVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGI 763
Query: 506 PVEKI 520
P+EKI
Sbjct: 764 PIEKI 768
[233][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 63.2 bits (152), Expect = 1e-08
Identities = 30/53 (56%), Positives = 40/53 (75%)
Frame = +2
Query: 362 LKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
L+R +E+L KL +++ +T+ALGTSK NYLDPRI+VAWCK VP+EKI
Sbjct: 895 LERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKI 947
[234][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 63.2 bits (152), Expect = 1e-08
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +2
Query: 272 DEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 451
DE +E K+ K + K+ ++LK ++ E R+ ++ ++ KED V+LGTSK
Sbjct: 673 DELEKEYKKELKTGKPIITKNATVEKLKQQIETLENRILNVSFQLKDKEDNSEVSLGTSK 732
Query: 452 QNYLDPRITVAWCKANEVPVEKI 520
NY+DPR+TV + K +VP+EK+
Sbjct: 733 MNYIDPRLTVMFSKKFDVPIEKL 755
[235][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 62.0 bits (149), Expect = 2e-08
Identities = 29/56 (51%), Positives = 40/56 (71%)
Frame = +2
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
K ++R E++L KL +E+ + +ALGTSK NYLDPRI+VAWCK +P+EKI
Sbjct: 729 KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKI 784
[236][TOP]
>UniRef100_Q95Z89 Possible DNA topoisomerase I-related protein n=1 Tax=Leishmania
major RepID=Q95Z89_LEIMA
Length = 262
Score = 62.0 bits (149), Expect = 2e-08
Identities = 31/70 (44%), Positives = 48/70 (68%)
Frame = +2
Query: 311 PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
P+ P+++S D K+ L+R ERL + + + +K+D + V+LGTSK NY+DPRI +W
Sbjct: 174 PRPPVVRSFPNDIGKA-LERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWA 232
Query: 491 KANEVPVEKI 520
KA +VP+ KI
Sbjct: 233 KAQDVPINKI 242
[237][TOP]
>UniRef100_Q8WQM6 DNA topoisomerase I-like protein n=1 Tax=Leishmania donovani
RepID=Q8WQM6_LEIDO
Length = 262
Score = 62.0 bits (149), Expect = 2e-08
Identities = 31/70 (44%), Positives = 48/70 (68%)
Frame = +2
Query: 311 PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
P+ P+++S D K+ L+R ERL + + + +K+D + V+LGTSK NY+DPRI +W
Sbjct: 174 PRPPVVRSFPNDIGKA-LERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWA 232
Query: 491 KANEVPVEKI 520
KA +VP+ KI
Sbjct: 233 KAQDVPINKI 242
[238][TOP]
>UniRef100_Q5RL92 Type IB topoisomerase small subunit n=1 Tax=Trypanosoma cruzi
RepID=Q5RL92_TRYCR
Length = 271
Score = 61.6 bits (148), Expect = 3e-08
Identities = 33/101 (32%), Positives = 59/101 (58%)
Frame = +2
Query: 218 EVTQYMPVKPEILESMTADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLT 397
E+ + + E +++ +E+ +E P+ P+++S + + L+R EERL +
Sbjct: 152 EIAKARGLVNECVDNKKEEEEEEEVAPVGPPPRPPIVRSFPSN-VDLALQRYEERLNREE 210
Query: 398 SDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + +K+D + V+LGTSK NY+DPRI +W K VP+ KI
Sbjct: 211 NMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKI 251
[239][TOP]
>UniRef100_Q38EP5 DNA topoisomerase type IB small subunit n=1 Tax=Trypanosoma brucei
RepID=Q38EP5_9TRYP
Length = 273
Score = 61.2 bits (147), Expect = 4e-08
Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 4/105 (3%)
Frame = +2
Query: 218 EVTQYMPVKPEILESMTADEKAQERKRAADL----PKVPLLKSMRGDQLKSNLKRAEERL 385
E+ + + +I + + E QE + + P+ L+S D +++ + + E+RL
Sbjct: 150 ELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRD-IEAEIGKHEKRL 208
Query: 386 AKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++MK+D +TV+LGTSK NY+DPRI +W N VP+ ++
Sbjct: 209 KDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRL 253
[240][TOP]
>UniRef100_C9ZXZ7 DNA topoisomerase type IB small subunit, putative n=2
Tax=Trypanosoma brucei RepID=C9ZXZ7_TRYBG
Length = 273
Score = 61.2 bits (147), Expect = 4e-08
Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 4/105 (3%)
Frame = +2
Query: 218 EVTQYMPVKPEILESMTADEKAQERKRAADL----PKVPLLKSMRGDQLKSNLKRAEERL 385
E+ + + +I + + E QE + + P+ L+S D +++ + + E+RL
Sbjct: 150 ELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRD-IEAEIGKHEKRL 208
Query: 386 AKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
+ + ++MK+D +TV+LGTSK NY+DPRI +W N VP+ ++
Sbjct: 209 KDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRL 253
[241][TOP]
>UniRef100_Q70HS8 DNA topoisomerase I subunit B (Fragment) n=1 Tax=Leishmania
panamensis RepID=Q70HS8_9TRYP
Length = 269
Score = 60.8 bits (146), Expect = 5e-08
Identities = 30/70 (42%), Positives = 47/70 (67%)
Frame = +2
Query: 311 PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
P+ P+++S D K+ L R ERL + + + +K+D + V+LGTSK NY+DPRI +W
Sbjct: 181 PRPPVVRSFPNDIGKA-LVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWA 239
Query: 491 KANEVPVEKI 520
KA +VP+ K+
Sbjct: 240 KAQDVPISKV 249
[242][TOP]
>UniRef100_A4H3S7 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania
braziliensis RepID=A4H3S7_LEIBR
Length = 269
Score = 60.8 bits (146), Expect = 5e-08
Identities = 30/70 (42%), Positives = 47/70 (67%)
Frame = +2
Query: 311 PKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWC 490
P+ P+++S D K+ L R ERL + + + +K+D + V+LGTSK NY+DPRI +W
Sbjct: 181 PRPPVVRSFPSDIGKA-LVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWA 239
Query: 491 KANEVPVEKI 520
KA +VP+ K+
Sbjct: 240 KAQDVPISKV 249
[243][TOP]
>UniRef100_Q4DUD0 DNA topoisomerase type IB small subunit, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DUD0_TRYCR
Length = 272
Score = 58.9 bits (141), Expect = 2e-07
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +2
Query: 272 DEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSK 451
+E+ +E P+ P+++S + + L+R EERL + + + +K+D + V+LGTSK
Sbjct: 171 NEEEEEVAPVGPPPRPPIVRSFPNN-VDLALQRYEERLNREENMIRIKDDNKAVSLGTSK 229
Query: 452 QNYLDPRITVAWCKANEVPVEKI 520
NY+DPRI +W K VP+ KI
Sbjct: 230 VNYIDPRIVCSWAKEYNVPIGKI 252
[244][TOP]
>UniRef100_B6KLS9 Voltage gated chloride channel domain-containing protein n=1
Tax=Toxoplasma gondii ME49 RepID=B6KLS9_TOXGO
Length = 1779
Score = 58.5 bits (140), Expect = 3e-07
Identities = 46/170 (27%), Positives = 70/170 (41%)
Frame = -2
Query: 515 SPQAPRWPCTKPR*CAGPGSFACWCPAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRPA 336
SP + P + P P + +PPS PPSS + P + S+ P+
Sbjct: 179 SPPSSSSPSSSPSSSTSPSPSSPPSSSPPSSSPPSSST------SPSPSSPPSSSPPSPS 232
Query: 335 CSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWP 156
++ P ++PP P PS S+P S + P+ + PP + P S P S+ P
Sbjct: 233 PPPSSPPSSSPPSSSPPSPSSPPPSSPPSSSSPSSSSPPPSSSPPSSSPPSSSSPSSSSP 292
Query: 155 AHA*APLPTQRPRHGGSPASASGPCAHWAASARGCTVPPPPCSACCKMPP 6
+ +P P P SP+ +S P S+ + PPP S PP
Sbjct: 293 PPSSSPPPPSPPSSSTSPSPSSPP------SSSPPSPSPPPSSPPSSSPP 336
Score = 53.9 bits (128), Expect = 6e-06
Identities = 52/171 (30%), Positives = 72/171 (42%)
Frame = -2
Query: 518 SSPQAPRWPCTKPR*CAGPGSFACWCPAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRP 339
SSP +P P + P + P S +PP PPSS P ++ P S + P
Sbjct: 226 SSPPSPSPPPSSPPSSSPPSSSPPSPSSPPPSSPPSSSSP----SSSSPPPSSSPPSSSP 281
Query: 338 ACSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTW 159
SS+ + + PP P PS SST S + P + PP P S P S+
Sbjct: 282 PSSSSPSSSSPPPSSSPPPPSPPSSSTSPSPSSPPSSS-PPSPSPPPSSPPSSSPPSSSP 340
Query: 158 PAHA*APLPTQRPRHGGSPASASGPCAHWAASARGCTVPPPPCSACCKMPP 6
P+ P P+ P SP S+S P ++S+ + PPP S PP
Sbjct: 341 PS---PPSPSSPP--PSSPPSSSSP----SSSSPPPSSSPPPPSPPSSSPP 382
[245][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 57.8 bits (138), Expect = 4e-07
Identities = 29/59 (49%), Positives = 42/59 (71%)
Frame = +2
Query: 344 DQLKSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCKANEVPVEKI 520
++ K+ +KR E+ L K+ +E+ + +ALGTSK NYLDPRI+VAWCK +PV+KI
Sbjct: 613 ERKKAAVKRCEQ-LLKMEIQATDREENKQIALGTSKLNYLDPRISVAWCKNMGLPVDKI 670
[246][TOP]
>UniRef100_UPI0000EB43B1 UPI0000EB43B1 related cluster n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB43B1
Length = 368
Score = 57.8 bits (138), Expect = 4e-07
Identities = 56/175 (32%), Positives = 69/175 (39%), Gaps = 10/175 (5%)
Frame = -2
Query: 518 SSPQAP-RWPCTKPR*CAGPGSFACW--CPAPPSGGPPSSPCPR*AWPAALPRA*GST*A 348
SSP+ P WP A P S+ W P PP+ GPP +P P +WP G +
Sbjct: 75 SSPRCPGAWPH------APPPSWRTWPCAPPPPAAGPPGAPPP--SWPRR-----GPSPR 121
Query: 347 GRPACSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPY 168
PACS A+ P P PVP+ P A P P Q Q SRP
Sbjct: 122 HPPACSEASPPQGPVPRAPPPVPAPSPVPAPSPHAYPRPLPHPGQG-----QAGAPSRPC 176
Query: 167 STW----PAHA*APLPTQRPRHGGSPASASGPCAHWAA---SARGCTVPPPPCSA 24
S P +P P Q H P P +A + R C+ PPP CS+
Sbjct: 177 SAQRRKAPGRECSPPPQQSAPHSTPPPRVF-PTPQQSAPHPTPRECSPPPPGCSS 230
[247][TOP]
>UniRef100_Q2HPH0 Topoisomerase I (Fragment) n=2 Tax=Laurasiatheria
RepID=Q2HPH0_BOVIN
Length = 67
Score = 57.0 bits (136), Expect = 8e-07
Identities = 27/47 (57%), Positives = 34/47 (72%)
Frame = +2
Query: 353 KSNLKRAEERLAKLTSDMEMKEDLQTVALGTSKQNYLDPRITVAWCK 493
K ++R EE+L KL +E+ + +ALGTSK NYLDPRITVAWCK
Sbjct: 18 KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 64
[248][TOP]
>UniRef100_A8J1N3 Cell wall protein pherophorin-C10 (Fragment) n=1 Tax=Chlamydomonas
reinhardtii RepID=A8J1N3_CHLRE
Length = 527
Score = 55.8 bits (133), Expect = 2e-06
Identities = 55/177 (31%), Positives = 62/177 (35%), Gaps = 8/177 (4%)
Frame = -2
Query: 512 PQAPRWPCTKPR*CAGPGSFACWCPAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRPAC 333
P +PR P KP P PAPPS PPS P P P P T G P
Sbjct: 201 PPSPRPPSPKPPSPPPPPGPPPPSPAPPSPSPPSPPPPS-PQPPVPPSPAPPTPPGPPPP 259
Query: 332 SSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPA 153
S A NPPP SP P + +PE + P PP E +P P P
Sbjct: 260 SPAPP---NPPPPPSPAPPSPKPPSPEPPSPPP----PPSPEPPSPKPPSPEPPSPQPPL 312
Query: 152 HA*APLPTQRPRHGGSPASASGPCAHWAASARGCTVPPPPCS--------ACCKMPP 6
P P SP S P A + PPPPC C +PP
Sbjct: 313 PPPPPSPYPPSPSPPSPPPPSPPPPSPAPPSPAPPSPPPPCECLAGERELTCAFLPP 369
[249][TOP]
>UniRef100_A7PAK3 Chromosome chr14 scaffold_9, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PAK3_VITVI
Length = 717
Score = 54.7 bits (130), Expect = 4e-06
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 2/147 (1%)
Frame = -2
Query: 440 PAPPSGGPPSSPCPR*AWPAALPRA*GST*AGRPACSSATAPWANPPPVFSPVPSHRQSS 261
P+PP+ PPS P P A P T A PA +S P +PPP PS R S
Sbjct: 88 PSPPASPPPSPPASPPPSPPASPPPSPPTSAPPPAVNSTPPPVLSPPPPSEGSPSPRVSP 147
Query: 260 TPESQA*PACTG*PPQAEKTRHQPWRLSRPYSTWPAHA*APLPTQRPRHGGSPASASG-- 87
P P+ PP + P + P S + + P P++ SP SG
Sbjct: 148 APPVGTPPS----PPAVSPSTPPPDNVPSPTS---SSSPPPPVASSPQNSPSPPPPSGSE 200
Query: 86 PCAHWAASARGCTVPPPPCSACCKMPP 6
P + AR PPPP PP
Sbjct: 201 PLSPPPTPARSTISPPPPSVPSSSSPP 227
[250][TOP]
>UniRef100_B4FTK0 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FTK0_MAIZE
Length = 269
Score = 54.3 bits (129), Expect = 5e-06
Identities = 44/116 (37%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Frame = -2
Query: 341 PACSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYS- 165
P SSA P PP +P P+ SS+P S A PA T P + P + P S
Sbjct: 137 PTPSSAPLPSPPSPPAAAPAPATSPSSSPPSSAAPAATPTSPTSPALAPAPAPTTTPSSP 196
Query: 164 ------TWPAHA*APLPTQRPRHGGSP---ASASGPCAHWAASARGCTVPPPPCSA 24
T P+ AP PT P GGSP ASAS P A +S T PP P +A
Sbjct: 197 PAPVPTTTPSSPPAPTPT-TPAGGGSPPPTASASAPAAEGGSS----TTPPQPSTA 247