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[1][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 155 bits (391), Expect = 2e-36
Identities = 78/158 (49%), Positives = 101/158 (63%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
++ +E P+ S +DV +F ++ +G+L PW E L ETV I+ L+ LN+ G
Sbjct: 377 SKKLQKEWAVPLNSSEDVNAIFAKYCQGTLSTHPWSELEGLQPETVQINEKLVALNQGGF 436
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+TINSQP VN S SVGWGGPGG+VYQKAYVEFF SPE A+ + A+ PSLT A
Sbjct: 437 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIA 496
Query: 404 AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
A E ++N NAVTWGVFP +E+IQPT+VDP
Sbjct: 497 VNAKG-ETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDP 533
[2][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 148 bits (374), Expect = 2e-34
Identities = 77/158 (48%), Positives = 99/158 (62%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
++ +E P+ S +DV +F ++ +G+L PW E L ET I+ L+ LN G
Sbjct: 377 SKKLQKEWAVPLNSCEDVNQIFAKYCQGTLSTHPWSELEGLQPETSQINDKLVALNTQGF 436
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+TINSQP VN S SVGWGGPGG+VYQKAYVEFF SPE A+ + A+ PSLT A
Sbjct: 437 LTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIA 496
Query: 404 AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
A E ++N NAVTWGVFP +E+IQPT+VDP
Sbjct: 497 VNAKG-ETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDP 533
[3][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 148 bits (374), Expect = 2e-34
Identities = 78/146 (53%), Positives = 102/146 (69%), Gaps = 2/146 (1%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAP 262
SEQDV +VF + G++KRLPW + S L+ E+ I L++LN+NG +TINSQP +N P
Sbjct: 399 SEQDVYNVFASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFLTINSQPAINGLP 457
Query: 263 STDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAA--KADSKELRTN 436
STD GWGG G VY+KAY+EFF+SPE T L + ++ P +T +A K DSK TN
Sbjct: 458 STDKQHGWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGDSK---TN 514
Query: 437 SKTPGANAVTWGVFPEREIIQPTIVD 514
+K G NAVTWG+FP +EIIQPT+VD
Sbjct: 515 TK--GTNAVTWGIFPGKEIIQPTVVD 538
[4][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 147 bits (370), Expect = 6e-34
Identities = 75/147 (51%), Positives = 93/147 (63%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S QD+ + FV F +G LK PW E L ET I L+ +N G +TINSQP VN
Sbjct: 375 PLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVN 434
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
A S SVGWGGPGG+VYQKAYVEFF + E L + ++ FPSLT A + + + +
Sbjct: 435 AEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESI-S 493
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVD 514
N NAVTWGVFP +EIIQPT+VD
Sbjct: 494 NIPANAVNAVTWGVFPGKEIIQPTVVD 520
[5][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 146 bits (368), Expect = 9e-34
Identities = 73/147 (49%), Positives = 93/147 (63%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F+ F +G L PW E L ET I L+ +N+ G +TINSQP VN
Sbjct: 387 PVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S SVGWGGPGG+VYQKAY+EFF S E D L + ++ FPSLT A D + +
Sbjct: 447 GERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESF-S 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVD 514
N T NAVTWGVFP +EI+QPT+VD
Sbjct: 506 NIPTNAVNAVTWGVFPGKEIVQPTVVD 532
[6][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 146 bits (368), Expect = 9e-34
Identities = 73/147 (49%), Positives = 93/147 (63%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F+ F +G L PW E L ET I L+ +N+ G +TINSQP VN
Sbjct: 30 PVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVN 89
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S SVGWGGPGG+VYQKAY+EFF S E D L + ++ FPSLT A D + +
Sbjct: 90 GERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESF-S 148
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVD 514
N T NAVTWGVFP +EI+QPT+VD
Sbjct: 149 NIPTNAVNAVTWGVFPGKEIVQPTVVD 175
[7][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 146 bits (368), Expect = 9e-34
Identities = 73/147 (49%), Positives = 93/147 (63%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F+ F +G L PW E L ET I L+ +N+ G +TINSQP VN
Sbjct: 387 PVKSVEDINERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S SVGWGGPGG+VYQKAY+EFF S E D L + ++ FPSLT A D + +
Sbjct: 447 GERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESF-S 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVD 514
N T NAVTWGVFP +EI+QPT+VD
Sbjct: 506 NIPTNAVNAVTWGVFPGKEIVQPTVVD 532
[8][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 145 bits (366), Expect = 2e-33
Identities = 75/148 (50%), Positives = 96/148 (64%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +DV + F G+LK PW E L ET I+ L +N NG +TINSQP VN
Sbjct: 197 PLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVN 256
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
AA S ++GWGGPGG+VYQKAY+EFF S + D L + ++ FPS+T Y A S+ +
Sbjct: 257 AAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSENWVS 315
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N+ NAVTWGVFP +E+IQPTIVDP
Sbjct: 316 NTGESDVNAVTWGVFPAKEVIQPTIVDP 343
[9][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 145 bits (366), Expect = 2e-33
Identities = 75/148 (50%), Positives = 96/148 (64%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +DV + F G+LK PW E L ET I+ L +N NG +TINSQP VN
Sbjct: 387 PLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
AA S ++GWGGPGG+VYQKAY+EFF S + D L + ++ FPS+T Y A S+ +
Sbjct: 447 AAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSENWVS 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N+ NAVTWGVFP +E+IQPTIVDP
Sbjct: 506 NTGESDVNAVTWGVFPAKEVIQPTIVDP 533
[10][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 143 bits (361), Expect = 6e-33
Identities = 72/148 (48%), Positives = 91/148 (61%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F F +G L PW E L ET I L+ +N+ G +TINSQP VN
Sbjct: 387 PLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S +VGWGGPGG+VYQKAY+EFF + E D L + + FPSLT A D + +
Sbjct: 447 GEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESF-S 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N NAVTWGVFP +EIIQPT+VDP
Sbjct: 506 NIAPNAVNAVTWGVFPGKEIIQPTVVDP 533
[11][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 142 bits (358), Expect = 1e-32
Identities = 73/150 (48%), Positives = 97/150 (64%), Gaps = 7/150 (4%)
Frame = +2
Query: 89 QDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
QDV DVF + G ++++PW + +LA ET I+ L +N G++TINSQP
Sbjct: 418 QDVCDVFTNYITGKESKNGKKVRKIPWND-DDLAAETSFINDKLARINSRGVLTINSQPN 476
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
VNAAPSTD VGWG PGG+V+QKAY+EFF+S E ALFK ++P++ + K + +
Sbjct: 477 VNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDD 536
Query: 428 RTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN AVTWGVFP +EIIQPT+VDP
Sbjct: 537 YTNCDQQQPIAVTWGVFPGKEIIQPTVVDP 566
[12][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 141 bits (355), Expect = 3e-32
Identities = 73/151 (48%), Positives = 96/151 (63%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ D+FVR+ +G L+ LPW E + E +I L+ LNR G +TINSQ
Sbjct: 374 KLWGTPLSIKDLSDLFVRYMEGKLESLPWSE-QPITGEATSIRNDLIDLNRRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A S+D + GWG G+VYQKAY+E SPE + ER P T YA D
Sbjct: 433 PAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+L+TN+ G NAVTWGVFP +EI+QPTIV+
Sbjct: 492 DLKTNAPNEGPNAVTWGVFPGKEIVQPTIVE 522
[13][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 140 bits (354), Expect = 4e-32
Identities = 72/147 (48%), Positives = 90/147 (61%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F F +G L PW E L ET I L+ +N+ G +TINSQP VN
Sbjct: 387 PLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S +VGWGGPGG+VYQKAY+EFF + E D L + + FPSLT A D E +
Sbjct: 447 GEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDG-ETFS 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVD 514
N NAVTWGVFP +EIIQPT+VD
Sbjct: 506 NISPNAVNAVTWGVFPGKEIIQPTVVD 532
[14][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 140 bits (353), Expect = 5e-32
Identities = 81/172 (47%), Positives = 102/172 (59%), Gaps = 7/172 (4%)
Frame = +2
Query: 23 GGLTNAD---ARAASRELYG----PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETV 181
GGLT+ RA ++L P+ S +DV + F++F G LK PW E L E+
Sbjct: 363 GGLTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESK 422
Query: 182 AISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL 361
I+ L +N G +TINSQP VN S +SVGWGGPGG+VYQKAY+EFF S E +AL
Sbjct: 423 IINELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNAL 482
Query: 362 FKAAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ PSLT A + + +N NAVTWGVFP REIIQPT+VDP
Sbjct: 483 VDKCKGHPSLTYMAVNKEGTWM-SNVGPGEVNAVTWGVFPAREIIQPTVVDP 533
[15][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 140 bits (353), Expect = 5e-32
Identities = 73/151 (48%), Positives = 95/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G +D+ D+FVR+ +G L LPW E + + E I + L+ LNR G +TINSQ
Sbjct: 374 KLWGSPMCIRDLSDLFVRYMEGKLDSLPWSEQA-ITTEAGPIRSDLIDLNRRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A S+D GWG G+VYQKAY+E F SPE + ER P T YA D
Sbjct: 433 PAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+L+TN+ G NAVTWGVFP +EI+QPTIV+
Sbjct: 492 DLKTNAPNEGPNAVTWGVFPGKEIVQPTIVE 522
[16][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 139 bits (349), Expect = 2e-31
Identities = 73/148 (49%), Positives = 87/148 (58%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S D+ + F F G LK PW E L ETV I+ L LNR G +TINSQP VN
Sbjct: 387 PLSSIVDIQEKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQLNRKGFLTINSQPAVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S S+GWGG G+VYQKAYVEFF SPE + L + A+ P +T Y A
Sbjct: 447 GEKSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVT-YIAVNKKGATAA 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N NAVTWGVFP +E+IQPT+VDP
Sbjct: 506 NIGPTDVNAVTWGVFPAKEVIQPTVVDP 533
[17][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 138 bits (348), Expect = 2e-31
Identities = 75/161 (46%), Positives = 96/161 (59%), Gaps = 4/161 (2%)
Frame = +2
Query: 47 RAASRELY----GPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNR 214
RA ++L+ P+ S +D+ + F + G LK PW E L ET I+ L +N
Sbjct: 388 RARGKKLFEEWASPLKSVEDIYEKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRINL 447
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLT 394
G +TINSQP VNA S SVGWGGPGG+VYQKAY+EFF S E +AL + + FP +T
Sbjct: 448 KGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVT 507
Query: 395 VYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
A + +N NAVTWGVFP +EIIQPT+VDP
Sbjct: 508 YMAVNRGGSWI-SNVALTDVNAVTWGVFPAKEIIQPTVVDP 547
[18][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 138 bits (348), Expect = 2e-31
Identities = 72/148 (48%), Positives = 93/148 (62%)
Frame = +2
Query: 74 PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVN 253
P+ S +D+ + F G+LK PW E L ET I+ L+ +N G +TINSQP VN
Sbjct: 387 PLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVN 446
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
A S +VGWGGP G+VYQKAY+EFF S E DA+ + + PS+T Y A ++ +
Sbjct: 447 AERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSIT-YMAVNKGEQWVS 505
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N+ NAVTWGVFP +EIIQPTIVDP
Sbjct: 506 NTAQADVNAVTWGVFPAKEIIQPTIVDP 533
[19][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 137 bits (345), Expect = 4e-31
Identities = 80/172 (46%), Positives = 101/172 (58%), Gaps = 7/172 (4%)
Frame = +2
Query: 23 GGLTNAD---ARAASRELYG----PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETV 181
GGLT+ RA ++L P+ S +DV + F++F G LK PW E L E+
Sbjct: 363 GGLTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESK 422
Query: 182 AISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL 361
I+ L +N G +TINSQP VN S +SVGWGGPGG+VYQKAY+EFF S E +AL
Sbjct: 423 IINELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNAL 482
Query: 362 FKAAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ SLT A + + +N NAVTWGVFP REIIQPT+VDP
Sbjct: 483 VDKCKGHTSLTYMAVNKEGTWM-SNVGPGEVNAVTWGVFPAREIIQPTVVDP 533
[20][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 137 bits (345), Expect = 4e-31
Identities = 69/143 (48%), Positives = 89/143 (62%)
Frame = +2
Query: 89 QDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAPST 268
+DV +VF + +G + +PW EA+ L E+ I L LNR G +TINSQP VNAA ST
Sbjct: 423 EDVYEVFALYIEGKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVNAALST 481
Query: 269 DMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRTNSKTP 448
S GWGGPGG++YQKAY E F SPE L ++ S+ VYA ++ ++
Sbjct: 482 HESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTELG 541
Query: 449 GANAVTWGVFPEREIIQPTIVDP 517
G A+TWGVFP REI+QPTI DP
Sbjct: 542 GVTALTWGVFPNREILQPTIFDP 564
[21][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 137 bits (345), Expect = 4e-31
Identities = 80/172 (46%), Positives = 101/172 (58%), Gaps = 7/172 (4%)
Frame = +2
Query: 23 GGLTNAD---ARAASRELYG----PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETV 181
GGLT+ RA ++L P+ S +DV + F++F G LK PW E L E+
Sbjct: 356 GGLTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPESK 415
Query: 182 AISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL 361
I+ L +N G +TINSQP VN S +SVGWGGPGG+VYQKAY+EFF S E +AL
Sbjct: 416 IINELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLNAL 475
Query: 362 FKAAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ SLT A + + +N NAVTWGVFP REIIQPT+VDP
Sbjct: 476 VDKCKGHTSLTYMAVNKEGTWM-SNVGPGEVNAVTWGVFPAREIIQPTVVDP 526
[22][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 137 bits (344), Expect = 6e-31
Identities = 78/162 (48%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
Frame = +2
Query: 32 TNADARAASRELYGPI-GSEQDVVDVFVRFFKGSLKRLPWVEASE-LANETVAISAPLLW 205
T R +R +G S DV VFV++ KG + LPW E L E AI PL
Sbjct: 372 TGEARREKARAAWGAAPASVDDVKQVFVKYIKGEVSLLPWAELDGGLTAEAAAIREPLAA 431
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN NG +TINSQPRVN S D GWGGPGG+VY KAYVEFF SPE L + P
Sbjct: 432 LNANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAP 491
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
S+T Y A + N NAVTWGVFP +E+IQPT+V
Sbjct: 492 SIT-YLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVV 532
[23][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 136 bits (343), Expect = 8e-31
Identities = 73/151 (48%), Positives = 97/151 (64%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FVR+ +G L RLPW + S ++ E AI L+ LN GL+T+NSQ
Sbjct: 374 KLWGEPKSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E F P + D L E+ P LT Y A A ++
Sbjct: 433 PAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT-YHAVAKNR 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F REI+QPTIVD
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREIVQPTIVD 521
[24][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 136 bits (343), Expect = 8e-31
Identities = 73/151 (48%), Positives = 97/151 (64%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FVR+ +G L RLPW + S ++ E AI L+ LN GL+T+NSQ
Sbjct: 374 KLWGEPKSIRDITQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E F P + D L E+ P LT Y A A ++
Sbjct: 433 PAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT-YHAVAKNR 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F REI+QPTIVD
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREIVQPTIVD 521
[25][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 136 bits (342), Expect = 1e-30
Identities = 74/161 (45%), Positives = 94/161 (58%), Gaps = 4/161 (2%)
Frame = +2
Query: 47 RAASRELYG----PIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNR 214
RA ++L+ P+ S +D+ + F + G LK PW E L ET I+ L +N
Sbjct: 389 RARDKKLHDEWVVPLSSAEDIFEKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKINL 448
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLT 394
G +TINSQP VN S SVGWGGPGG+VYQKAY+EFF S + AL + + P LT
Sbjct: 449 KGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLT 508
Query: 395 VYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
Y A L +N NAVTWGVFP ++IIQPT+VDP
Sbjct: 509 -YMAVNRGGTLLSNVGQNDVNAVTWGVFPGKQIIQPTVVDP 548
[26][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 135 bits (341), Expect = 1e-30
Identities = 74/163 (45%), Positives = 98/163 (60%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
G+T DA L+G + D+ +F RF +G L +LPW A+ET I L
Sbjct: 371 GITAPDAY----NLWGHPTTSSDLHALFARFCRGDLAKLPW-STQPPASETSLIIEQLAK 425
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
+N G +TINSQP V+ S D GWG PGG+VYQKAY+EFF SP++ L + E+ P
Sbjct: 426 MNELGYLTINSQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDP 485
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+T YA +LRTN+ + NAVTWGVFP +EI+QPTIV+
Sbjct: 486 RITYYAVNKQG-DLRTNTHSESPNAVTWGVFPGKEIVQPTIVE 527
[27][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 135 bits (340), Expect = 2e-30
Identities = 82/183 (44%), Positives = 109/183 (59%), Gaps = 11/183 (6%)
Frame = +2
Query: 2 NHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS-------LKRLPWVEA 157
+++L + NAD R A ++G I S +DV VF+ + + + LPW EA
Sbjct: 395 SYYLSNLTTVRNADDRLA---MFGANIESFEDVKRVFINYITQAPNADGVKVTVLPWTEA 451
Query: 158 SE-LANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF 334
+ ET IS L+W N NG++T+NSQP VN APSTD VGWG PGG+ YQKAY+E F
Sbjct: 452 ETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECF 511
Query: 335 SSPEMTDALFKAAER-FP-SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTI 508
+ E++D L + ER FP + +A DS +TNS+ AVTWGVFP EI QPT+
Sbjct: 512 MTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTV 571
Query: 509 VDP 517
VDP
Sbjct: 572 VDP 574
[28][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 135 bits (340), Expect = 2e-30
Identities = 78/165 (47%), Positives = 98/165 (59%), Gaps = 4/165 (2%)
Frame = +2
Query: 32 TNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWL 208
T A R ++G + + V VF F KG +KRLPW ET+ I L+ L
Sbjct: 347 TQEKVAADRRRMWGDHVPNGDHVRRVFTDFIKGEVKRLPWCTEPP-TEETLFIQKQLIRL 405
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKA--AERF 382
N+ ++TINSQPRVN A STD VGWG GGFVYQKAYVEFF + L + AE++
Sbjct: 406 NQCNMLTINSQPRVNGALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKY 465
Query: 383 PSLTVYAAKADSKELRTNSKTPG-ANAVTWGVFPEREIIQPTIVD 514
S++ A AD ++R+N G NAVTWGVFP EIIQPT+VD
Sbjct: 466 DSISYMAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVD 510
[29][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 135 bits (340), Expect = 2e-30
Identities = 67/151 (44%), Positives = 100/151 (66%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ ++FV + + ++ LPW EA +++E I + L+ LNR G +TINSQ
Sbjct: 374 KLWGQPKSIKDIAELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNRRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P V+ S+D GWG G+VYQKAY+E +P+M L + + P LT YA K +
Sbjct: 433 PAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVK-KTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+L+TN+++ G NAVTWGVFP +EI+QPTIV+
Sbjct: 492 DLQTNAQSDGPNAVTWGVFPGKEIVQPTIVE 522
[30][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 135 bits (340), Expect = 2e-30
Identities = 73/151 (48%), Positives = 97/151 (64%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +DV +FVR+ +G L RLPW + S ++ E AI L+ LN GL+T+NSQ
Sbjct: 374 KLWGEPKSIRDVTQIFVRYLEGKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E F P + D L E+ P LT Y A A ++
Sbjct: 433 PAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLT-YHAVAKNR 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F REI+QPTIV+
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREIVQPTIVE 521
[31][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 135 bits (340), Expect = 2e-30
Identities = 82/183 (44%), Positives = 109/183 (59%), Gaps = 11/183 (6%)
Frame = +2
Query: 2 NHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS-------LKRLPWVEA 157
+++L + NAD R A ++G I S +DV VF+ + + + LPW EA
Sbjct: 416 SYYLSNLTTVRNADDRLA---MFGANIESFEDVKRVFINYITQAPNADGVKVTVLPWTEA 472
Query: 158 SE-LANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF 334
+ ET IS L+W N NG++T+NSQP VN APSTD VGWG PGG+ YQKAY+E F
Sbjct: 473 ETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECF 532
Query: 335 SSPEMTDALFKAAER-FP-SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTI 508
+ E++D L + ER FP + +A DS +TNS+ AVTWGVFP EI QPT+
Sbjct: 533 MTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTV 592
Query: 509 VDP 517
VDP
Sbjct: 593 VDP 595
[32][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 135 bits (339), Expect = 2e-30
Identities = 73/153 (47%), Positives = 96/153 (62%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
++E++G DV +F +F G +K LPW E + +A ET IS L +N+ G +TIN
Sbjct: 389 AKEMWGAPTCLDDVKTLFQQFCAGQVKALPWSE-TPVARETSVISDKLAKMNQLGFLTIN 447
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP V+ A S D GWG G+VYQKAY+EFF SPE DAL E P +T +A +
Sbjct: 448 SQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQ 507
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
++RTN+ + NAVTWGVFP EIIQPTIV+
Sbjct: 508 G-DMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE 539
[33][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 134 bits (338), Expect = 3e-30
Identities = 69/145 (47%), Positives = 87/145 (60%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAP 262
+E DV +VF R+ +GS+ +PW E + L E+ I L LNR G +T+NSQP V+ P
Sbjct: 382 AESDVYEVFARYVEGSVPHIPWCE-TPLQPESFLIQPQLAKLNRYGFLTVNSQPPVDGLP 440
Query: 263 STDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRTNSK 442
S GWGG GG VYQKAY E F SP + L + PSL +YA +ELR +
Sbjct: 441 SCHKVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVE 500
Query: 443 TPGANAVTWGVFPEREIIQPTIVDP 517
G A+TWGVFP REI+QPTI DP
Sbjct: 501 EGGVTALTWGVFPNREILQPTIFDP 525
[34][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 134 bits (337), Expect = 4e-30
Identities = 73/140 (52%), Positives = 89/140 (63%), Gaps = 3/140 (2%)
Frame = +2
Query: 104 VFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVG 283
VF F KG +KRLPW ET+ I L+ LN+ ++TINSQPRVN A STD VG
Sbjct: 351 VFTDFIKGEVKRLPWCTEPP-TEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVG 409
Query: 284 WGGPGGFVYQKAYVEFFSSPEMTDALFKA--AERFPSLTVYAAKADSKELRTNSKTPG-A 454
WG GGFVYQKAYVEFF + L + AE++ S++ A AD ++R+N G
Sbjct: 410 WGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQV 469
Query: 455 NAVTWGVFPEREIIQPTIVD 514
NAVTWGVFP EIIQPT+VD
Sbjct: 470 NAVTWGVFPNSEIIQPTVVD 489
[35][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 134 bits (336), Expect = 5e-30
Identities = 71/152 (46%), Positives = 89/152 (58%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
E P+ S +D+ + F + G LK PW E L ET I+ L +N G +TINSQ
Sbjct: 394 EWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQ 453
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S SVGWGGPGG+VYQKAY+EFF S + +AL + FP +T A
Sbjct: 454 PAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGS 513
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ +N NAVTWGVFP +EIIQPT+VDP
Sbjct: 514 WI-SNVALTDVNAVTWGVFPGKEIIQPTVVDP 544
[36][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 134 bits (336), Expect = 5e-30
Identities = 71/152 (46%), Positives = 89/152 (58%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
E P+ S +D+ + F + G LK PW E L ET I+ L +N G +TINSQ
Sbjct: 13 EWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQ 72
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S SVGWGGPGG+VYQKAY+EFF S + +AL + FP +T A
Sbjct: 73 PAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGS 132
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ +N NAVTWGVFP +EIIQPT+VDP
Sbjct: 133 WI-SNVALTDVNAVTWGVFPGKEIIQPTVVDP 163
[37][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 134 bits (336), Expect = 5e-30
Identities = 72/151 (47%), Positives = 92/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + QD+ +F RF G L LPW +A LA ET I+ PL LN G TINSQ
Sbjct: 300 DLWGSPTTIQDLQSLFARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQ 358
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P V+ A S D GWG G+VYQKAY+EFF SP+ D L + P +T +A A
Sbjct: 359 PAVDGARSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQG- 417
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
++RTN+ + NAVTWG FP EI+QPTIV+
Sbjct: 418 DMRTNTTSDAPNAVTWGCFPHCEILQPTIVE 448
[38][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 133 bits (334), Expect = 8e-30
Identities = 72/163 (44%), Positives = 98/163 (60%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GLT ++ A+R+ +G + QD+ ++FV + ++ LPW E S L E I L+
Sbjct: 364 GLTGSNE--ANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIE 420
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN+ GL+TINSQP VN S+ GWG G+VYQK+Y+E P + D + E P
Sbjct: 421 LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP 480
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
LT YA D ELR+N + G NAVTWGVFP +EI+QPTIV+
Sbjct: 481 DLTYYAVTKDG-ELRSNVTSDGPNAVTWGVFPGKEIVQPTIVE 522
[39][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 132 bits (332), Expect = 1e-29
Identities = 73/151 (48%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ D+F+R+ G L+RLPW ++S + ET I LL LN+ G +TINSQ
Sbjct: 375 KLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSS-VTLETSDIQNELLDLNKRGFLTINSQ 433
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN STD GWG GFVYQKAY+E PE + L + E+ P LT Y +
Sbjct: 434 PAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCIN-KTG 492
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELR S G NAVTWG+F +EIIQPTIV+
Sbjct: 493 ELRARS-DEGPNAVTWGIFASKEIIQPTIVE 522
[40][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 132 bits (331), Expect = 2e-29
Identities = 72/163 (44%), Positives = 100/163 (61%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GLT ++ +R+ +G + +D+ ++FVR+ L+ LPW EA +++E I L+
Sbjct: 364 GLTGSNE--LNRKKWGEPQTVKDIANLFVRYLNQELEYLPWSEAP-ISSEAELIKDDLIA 420
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN GL+TINSQP VN ST GWG G+VYQKAY+E SPE+ + + E P
Sbjct: 421 LNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHP 480
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+T YA S L TN+ + G NAVTWGVFP +EI+QPTIV+
Sbjct: 481 DITYYAV-TKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVE 522
[41][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 132 bits (331), Expect = 2e-29
Identities = 70/151 (46%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++FVRF G+L RLPW E + + ET + LL LNR G +TINSQ
Sbjct: 374 KLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGA-VTEETDVLKLDLLDLNRRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ PS+ GWG G+VYQKAY+E SP + D + E+ P LT Y
Sbjct: 433 PAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELRTNT-TDSPNAVTWGIFASKEIIQPTIVE 521
[42][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 132 bits (331), Expect = 2e-29
Identities = 71/151 (47%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++FVRF G+L RLPW E + + ET I LL LNR G +TINSQ
Sbjct: 360 KLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGA-VTEETDVIKLDLLDLNRRGFLTINSQ 418
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ PS+ GWG G+VYQKAY+E SP + D + E+ P LT Y
Sbjct: 419 PAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIG- 477
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 478 ELRTNT-TDSPNAVTWGIFASKEIIQPTIVE 507
[43][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 131 bits (330), Expect = 2e-29
Identities = 70/151 (46%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++F+RF GSL RLPW E + + ET I + LL LNR G +TINSQ
Sbjct: 374 KLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGA-VTEETEIIKSDLLDLNRKGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ PS+ GWG G+VYQKAY+E SP M D + E+ LT Y
Sbjct: 433 PAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELKTNT-TDSPNAVTWGIFASKEIIQPTIVE 521
[44][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 131 bits (330), Expect = 2e-29
Identities = 70/151 (46%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++F+RF GSL RLPW E + + ET I + LL LNR G +TINSQ
Sbjct: 374 KLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGA-VTEETEIIKSDLLDLNRKGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ PS+ GWG G+VYQKAY+E SP M D + E+ LT Y
Sbjct: 433 PAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELKTNT-TDSPNAVTWGIFASKEIIQPTIVE 521
[45][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 131 bits (330), Expect = 2e-29
Identities = 71/152 (46%), Positives = 95/152 (62%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ D+F+RF +G L RLPW E S + E+ I L+ LN G +TINSQ
Sbjct: 374 KLWGEPKSVKDLSDIFIRFLEGKLDRLPWSE-SAITQESDIIKDDLIALNNRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N A S+ GWG G+VYQKAY+E SP + D + + E P LT + +
Sbjct: 433 PAINGAKSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNG- 491
Query: 422 ELRTNSK-TPGANAVTWGVFPEREIIQPTIVD 514
ELRTNS TP NAVTWG+F +E+IQPTIV+
Sbjct: 492 ELRTNSSDTP--NAVTWGIFASKEVIQPTIVE 521
[46][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 131 bits (330), Expect = 2e-29
Identities = 74/159 (46%), Positives = 93/159 (58%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G S DV+D+FVR+ +G+L LPW + E + E + LL LNR G++TINSQ
Sbjct: 372 ELWGKPQSIDDVIDLFVRYLQGNLSSLPWSDG-ETSKEINVLLDDLLALNRQGILTINSQ 430
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAE--------RFPSLTV 397
P VN PS GWG GFVYQK Y+EFF + L E F +LT
Sbjct: 431 PCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTF 490
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
YA A EL TNSK NAVTWG+FP +E++QPTIV+
Sbjct: 491 YAVNAQG-ELITNSKEDDINAVTWGIFPGKEVVQPTIVE 528
[47][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 131 bits (330), Expect = 2e-29
Identities = 72/151 (47%), Positives = 93/151 (61%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ D+FVR+ G ++RLPW + S + ET I LL LN+ G +TINSQ
Sbjct: 375 KLWGAPKSIKDLSDIFVRYLNGKVERLPWSD-SAVTPETSDIQNELLDLNKRGFLTINSQ 433
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN STD GWG G+VYQKAY+E PE D L + E+ P LT Y +
Sbjct: 434 PAVNGVKSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVN-KTG 492
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+ S G NAVTWG+F +EIIQPTIV+
Sbjct: 493 ELKARS-DEGPNAVTWGIFASKEIIQPTIVE 522
[48][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 131 bits (329), Expect = 3e-29
Identities = 67/154 (43%), Positives = 94/154 (61%), Gaps = 7/154 (4%)
Frame = +2
Query: 77 IGSEQDVVDVFVRFFKG-------SLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
+ SEQDV D+FV + G + LPW + ELA ET+ + L+ N+NG++TIN
Sbjct: 399 LNSEQDVFDIFVCYLTGRDNKQGFKVTELPWSDG-ELAPETIPLVEKLVHANQNGILTIN 457
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP +NA PS D + GWG PGG+V+QKAY+EFF+ E+ L+ + + + +
Sbjct: 458 SQPSLNAVPSEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSS 517
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ TN+ NAVTWGVFP EI+QPT+VDP
Sbjct: 518 GESDFTNANMYSPNAVTWGVFPGSEILQPTVVDP 551
[49][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 131 bits (329), Expect = 3e-29
Identities = 69/150 (46%), Positives = 91/150 (60%), Gaps = 7/150 (4%)
Frame = +2
Query: 89 QDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
QDV +VF + G + LPW + ELA ET I L+ N NG+++INSQP
Sbjct: 374 QDVFEVFKCYISGEKNENGVKVTSLPWND-EELALETSFIKEKLIHFNSNGILSINSQPS 432
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
VNAA STD +GWGG GG++YQKAY+EFF+SPE+ L + + +P + +
Sbjct: 433 VNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVD 492
Query: 428 RTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN + AVTWGVFP REI+QPT+VDP
Sbjct: 493 ITNCDSQTPVAVTWGVFPGREIVQPTVVDP 522
[50][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 131 bits (329), Expect = 3e-29
Identities = 73/163 (44%), Positives = 99/163 (60%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GLT ++ + +R+ +G S +D+ ++FVR+ ++ LPW EA +A E I L+
Sbjct: 364 GLTGSNEQ--NRKKWGEPTSIKDIANLFVRYLNKEIEYLPWSEAP-VAEEADLIKDDLIE 420
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN GL+T+NSQP VN ST GWG G+VYQKAY+E SPE+ + E P
Sbjct: 421 LNNRGLITVNSQPAVNGVKSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHP 480
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
LT Y A S L TN++ G NAVTWGVFP +EI+QPTIV+
Sbjct: 481 DLT-YHAVTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPTIVE 522
[51][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 131 bits (329), Expect = 3e-29
Identities = 70/151 (46%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++FVRF G+L RLPW E + + ET + LL LNR G +TINSQ
Sbjct: 265 KLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGA-VTEETDVLKLDLLDLNRRGFLTINSQ 323
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ PS+ GWG G+VYQKAY+E SP + D + E+ P LT Y
Sbjct: 324 PAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIG- 382
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 383 ELRTNT-TDSPNAVTWGIFASKEIIQPTIVE 412
[52][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 130 bits (328), Expect = 4e-29
Identities = 70/163 (42%), Positives = 99/163 (60%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GLT + A+R+ +G + QD+ +FVR+ + + LPW E S L +E I L+
Sbjct: 364 GLTGTNE--ANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSE-SPLTSEADEIRDDLVE 420
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN+ GL+T+NSQP VN S+ GWG G+VYQK+Y+E P++ + + E P
Sbjct: 421 LNKRGLLTVNSQPAVNGVKSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHP 480
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
LT YA D ELR+N+ + NAVTWGVFP +EI+QPTIV+
Sbjct: 481 DLTFYAVTKDG-ELRSNAPSDCPNAVTWGVFPGKEIVQPTIVE 522
[53][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 130 bits (327), Expect = 5e-29
Identities = 79/183 (43%), Positives = 107/183 (58%), Gaps = 11/183 (6%)
Frame = +2
Query: 2 NHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS-------LKRLPWVEA 157
+++L L N D R + ++G I S +DV VF+ + + + LPW EA
Sbjct: 417 SYYLSNLTTLRNGDDRLS---MFGENIESIEDVKRVFINYITQTPNVSGKKVTVLPWTEA 473
Query: 158 SE-LANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF 334
+ ET IS L+W N NG++T+NSQP VN APSTD VGWG PGG+ YQKAY+E F
Sbjct: 474 ETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECF 533
Query: 335 SSPEMTDALFKAAER-FP-SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTI 508
+ E+++ L ER +P + +A DS +TNS+ AVTWGVFP EI QPT+
Sbjct: 534 MTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPIAVTWGVFPGSEIAQPTV 593
Query: 509 VDP 517
VDP
Sbjct: 594 VDP 596
[54][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 130 bits (326), Expect = 7e-29
Identities = 74/163 (45%), Positives = 99/163 (60%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GLT + + +R+ +G +D+ ++FVR+ K ++ LPW EA +A E I LL
Sbjct: 364 GLTGTNEQ--NRQKWGEPTCIRDIANLFVRYLKKEIEYLPWSEAP-VAEEADLIKDYLLD 420
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LN+ GL+T+NSQP VN ST GWG G+VYQKAY+E SPE+ + K E P
Sbjct: 421 LNKRGLITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHP 480
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
LT Y A S L TN+ + NAVTWGVFP +EI+QPTIV+
Sbjct: 481 DLT-YHAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVE 522
[55][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 450 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 508
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 509 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 568
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 569 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 600
[56][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 468 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 526
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 527 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 586
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 587 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 618
[57][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 450 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 508
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 509 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 568
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 569 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 600
[58][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 468 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 526
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 527 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 586
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 587 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 618
[59][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 427 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 485
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 486 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 545
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 546 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 577
[60][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 129 bits (325), Expect = 9e-29
Identities = 70/152 (46%), Positives = 92/152 (60%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 427 SEESVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 485
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 486 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 545
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 546 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 577
[61][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 129 bits (323), Expect = 2e-28
Identities = 72/151 (47%), Positives = 92/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +VFVRF +G+L RLPW + S + ET AI L+ LNR G TINSQ
Sbjct: 374 KLWGEPNSLRDLAEVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNRRGFFTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E P + D L E LT Y A
Sbjct: 433 PAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLT-YHAVTKKG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F RE++QPTIV+
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREVVQPTIVE 521
[62][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 129 bits (323), Expect = 2e-28
Identities = 71/151 (47%), Positives = 95/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FVR+ +G L+RLPW + S ++ E AI L+ LN GL+T+NSQ
Sbjct: 374 KLWGEPKSIRDISQIFVRYVEGKLERLPWSD-SPISAEANAIKENLIELNGRGLLTVNSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E F P + D L E+ LT Y A A
Sbjct: 433 PAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLT-YHAVAKEG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F REI+QPTIV+
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREIVQPTIVE 521
[63][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 128 bits (322), Expect = 2e-28
Identities = 70/152 (46%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE V +VFV + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 457 SEASVFEVFVLYLSGEPNRNGHKVTCLPWND-EPLAAETSLLKEELLRVNRQGILTINSQ 515
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 516 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG 575
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 576 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 607
[64][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 127 bits (320), Expect = 3e-28
Identities = 69/152 (45%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF R+ G + LPW + LA ET + LL +NR G++TINSQ
Sbjct: 552 SEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQ 610
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E AL + +++ Y
Sbjct: 611 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKG 670
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 671 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 702
[65][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 127 bits (320), Expect = 3e-28
Identities = 69/152 (45%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF R+ G + LPW + LA ET + LL +NR G++TINSQ
Sbjct: 468 SEESVFEVFARYLSGEPNQHGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGILTINSQ 526
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E AL + +++ Y
Sbjct: 527 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKG 586
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 587 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 618
[66][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 127 bits (320), Expect = 3e-28
Identities = 68/150 (45%), Positives = 87/150 (58%), Gaps = 8/150 (5%)
Frame = +2
Query: 92 DVVDVFVRFFKGSLK-------RLPWVEASE-LANETVAISAPLLWLNRNGLMTINSQPR 247
D+ VFV F ++ +LPW E + + ET I LLW N NG +TINSQP
Sbjct: 443 DIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQPS 502
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
+N APSTD VGWG PGG+ YQKAY+EFF+S + L+ + L + D+
Sbjct: 503 INGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATID 562
Query: 428 RTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN++T AVTWGVFP EI QPT+VDP
Sbjct: 563 WTNTETTMPIAVTWGVFPGSEIAQPTVVDP 592
[67][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 127 bits (319), Expect = 5e-28
Identities = 68/151 (45%), Positives = 93/151 (61%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +F+RF +G L RLPW E S + ET I L+ LN G +TINSQ
Sbjct: 374 KLWGEPKSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKQDLIDLNNRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG G+VYQKAY+E PE+ + + E+ P LT YA +
Sbjct: 433 PAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN+ + NAVTWG+F +E+IQPTIV+
Sbjct: 492 ELKTNT-SDSPNAVTWGIFASKEVIQPTIVE 521
[68][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 127 bits (319), Expect = 5e-28
Identities = 68/151 (45%), Positives = 92/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S D+ +F RF L LPW + + + ET I+ L +N G +TINSQ
Sbjct: 375 KLWGHPTSFADIASLFSRFCTKKLSALPWSDQAP-SQETSVIAEQLATMNEFGFLTINSQ 433
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN+A S D GWG G+VYQKAY+EFF +P + + L ER ++T Y
Sbjct: 434 PAVNSARSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRG- 492
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+LRTN+ + G NAVTWGVFP +EI+QPTIV+
Sbjct: 493 DLRTNTHSDGPNAVTWGVFPGKEIVQPTIVE 523
[69][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 127 bits (319), Expect = 5e-28
Identities = 68/151 (45%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + ++V +F +F KG L LPW +++ + ET I+ L +N G +TINSQ
Sbjct: 335 KLWGYPTTLEEVSVLFAKFCKGELDALPWSDSAP-SKETSIIATQLAKMNELGFLTINSQ 393
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A S D GWG G+VYQKAY+EFF P + L K ER ++T +
Sbjct: 394 PAVNGARSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRG- 452
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+L+TN+ + G NAVTWGVFP +EIIQPTIV+
Sbjct: 453 DLQTNTHSEGPNAVTWGVFPGKEIIQPTIVE 483
[70][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 127 bits (318), Expect = 6e-28
Identities = 70/152 (46%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 467 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 525
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +NA PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 526 PNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 585
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 586 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 617
[71][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 127 bits (318), Expect = 6e-28
Identities = 70/152 (46%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 467 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 525
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +NA PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 526 PNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 585
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 586 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 617
[72][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 127 bits (318), Expect = 6e-28
Identities = 70/152 (46%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 467 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 525
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +NA PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 526 PNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 585
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 586 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 617
[73][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 127 bits (318), Expect = 6e-28
Identities = 68/151 (45%), Positives = 93/151 (61%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +F+RF +G L RLPW E S + ET I L+ LN G +TINSQ
Sbjct: 374 KLWGEPKSIKDLSAIFIRFLEGGLDRLPWSE-SPITEETDDIKHDLIDLNNRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG G+VYQKAY+E PE+ + + E+ P LT YA +
Sbjct: 433 PAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN+ + NAVTWG+F +E+IQPTIV+
Sbjct: 492 ELKTNT-SDSPNAVTWGIFASKEVIQPTIVE 521
[74][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 127 bits (318), Expect = 6e-28
Identities = 69/151 (45%), Positives = 95/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FV+F +G L RLPW + + ++ E AI L+ LN+ GL TINSQ
Sbjct: 374 KLWGEPKSIRDLAHIFVKFMQGELARLPWSD-TPISGEANAIKDKLIELNKRGLFTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A S+ GWG GFVYQKAY+E P + D L E+ LT Y A + +
Sbjct: 433 PAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLT-YHAVSKTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F RE++QPTIV+
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREVVQPTIVE 521
[75][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 127 bits (318), Expect = 6e-28
Identities = 70/152 (46%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 426 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 484
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +NA PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 485 PNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 544
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 545 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 576
[76][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 126 bits (317), Expect = 8e-28
Identities = 68/152 (44%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G + LPW + LA ET + LL +NR G++TINSQ
Sbjct: 426 SEESVFEVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRQGVLTINSQ 484
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 485 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKG 544
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 545 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 576
[77][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 126 bits (317), Expect = 8e-28
Identities = 68/152 (44%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G + LPW + LA ET + LL +N+ G++TINSQ
Sbjct: 421 SEESVFEVFTYYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLKVNQRGILTINSQ 479
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PSTD VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 480 PNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKG 539
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 540 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 571
[78][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 126 bits (317), Expect = 8e-28
Identities = 72/171 (42%), Positives = 95/171 (55%), Gaps = 8/171 (4%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L N + +++G + S +DV ++F F G + LPW + LA ET+
Sbjct: 392 LKNTSKKDELLKMWGEKLESVEDVYEIFTCFVSGERNKYGYKVDALPWSNDA-LALETLF 450
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
I L ++N G++TINSQP VNA PST GWGGP G+VYQKAY+EFF S E L
Sbjct: 451 IKKSLEYINSKGILTINSQPNVNALPSTHEVFGWGGPNGYVYQKAYLEFFISAERFKTLL 510
Query: 365 KAAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ FP + +A +NS AVTWGVFP REI+QPT+VDP
Sbjct: 511 EVLPNFPMINYHALDLSESINVSNSDHHQPIAVTWGVFPGREILQPTVVDP 561
[79][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 126 bits (317), Expect = 8e-28
Identities = 81/193 (41%), Positives = 108/193 (55%), Gaps = 21/193 (10%)
Frame = +2
Query: 2 NHHLVGSGGLTNADARAASRELYGP-IGSEQDVVDVFVRFFKGS-------LKRLPWVEA 157
+++L L N D R + ++G I S +DV VF+ + + + LPW EA
Sbjct: 467 SYYLSNLTTLRNGDDRLS---MFGENIESIEDVKRVFINYITQTPNVSGKKVTVLPWTEA 523
Query: 158 SE-LANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF 334
+ ET IS L+W N NG++T+NSQP VN APSTD VGWG PGG+ YQKAY+E F
Sbjct: 524 ETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECF 583
Query: 335 SSPEMTDALFKAAER-FPSLTVYAA----------KADSKEL-RTNSKTPGANAVTWGVF 478
+ E+++ L ER +P Y A DS ++ RTNS+ AVTWGVF
Sbjct: 584 MTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVF 643
Query: 479 PEREIIQPTIVDP 517
P EI QPT+VDP
Sbjct: 644 PGSEIAQPTVVDP 656
[80][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 126 bits (317), Expect = 8e-28
Identities = 67/151 (44%), Positives = 93/151 (61%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FVRF + L RLPW E+S + ET I L+ LN G +TINSQ
Sbjct: 374 KLWGEPKSIKDLSSIFVRFLEAKLDRLPWSESS-ITEETDIIKQDLIDLNNRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N A S+ GWG G+VYQKAY+E PE+ D + ++ LT YA +
Sbjct: 433 PAINGASSSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNG- 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN+ + NAVTWG+F +E+IQPTIV+
Sbjct: 492 ELKTNT-SDSPNAVTWGIFASKEVIQPTIVE 521
[81][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 126 bits (316), Expect = 1e-27
Identities = 68/152 (44%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V VF + G + LPW + LA ET + LL +NR G++TINSQ
Sbjct: 426 SEESVFQVFAHYLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQ 484
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 485 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKG 544
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 545 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 576
[82][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 126 bits (316), Expect = 1e-27
Identities = 69/155 (44%), Positives = 93/155 (60%), Gaps = 8/155 (5%)
Frame = +2
Query: 77 IGSEQDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
+ SE+ V +VF + G + LPW + LA ET + L +N+ G++TIN
Sbjct: 419 LNSEESVFEVFTYYISGEPNPNGHKVNCLPWND-DPLAPETNLLKNELQKVNKRGILTIN 477
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF-PSLTVYAAKA 412
SQP VN PSTD VGWG G+V+QKAY+EFF+S EM AL K +R+ P + +
Sbjct: 478 SQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNV 537
Query: 413 DSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ + TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 538 HGQNI-TNAADLQPNAVTWGIFPGREIIQPTVVDP 571
[83][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 125 bits (313), Expect = 2e-27
Identities = 68/152 (44%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 432 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 490
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 491 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 550
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REI+QPT+VDP
Sbjct: 551 ENITNAPELQPNAVTWGIFPGREIVQPTVVDP 582
[84][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 125 bits (313), Expect = 2e-27
Identities = 68/152 (44%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G R LPW + LA ET + LL +NR G++TINSQ
Sbjct: 467 SEESVFEVFEHYLSGEPNRHGYRVTCLPWND-EPLAAETSLMKEELLRVNRLGILTINSQ 525
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y
Sbjct: 526 PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKG 585
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REI+QPT+VDP
Sbjct: 586 ENITNAPELQPNAVTWGIFPGREIVQPTVVDP 617
[85][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 124 bits (312), Expect = 3e-27
Identities = 68/152 (44%), Positives = 88/152 (57%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V +VF + G + LPW + LA ET + L +NR G++TINSQ
Sbjct: 424 SEESVFEVFAYYLSGEPNQNGYKVTCLPWND-EPLAAETSLLKEELQKVNRRGILTINSQ 482
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS D VGWG GG+V+QKAY+EFF+S E AL K +++ Y
Sbjct: 483 PNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKG 542
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 543 ENITNAPDMQPNAVTWGIFPGREIIQPTVVDP 574
[86][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 124 bits (312), Expect = 3e-27
Identities = 68/155 (43%), Positives = 94/155 (60%), Gaps = 8/155 (5%)
Frame = +2
Query: 77 IGSEQDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
+ SE+ V +VF + G + LPW + LA ET + + L +N+ G++TIN
Sbjct: 419 LSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTIN 477
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF-PSLTVYAAKA 412
SQP VN PSTD VGWG G+V+QKAY+EFF+S EM AL K +R+ P + +
Sbjct: 478 SQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNV 537
Query: 413 DSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ + TN+ +AVTWG+FP REIIQPT+VDP
Sbjct: 538 HGQNI-TNAADLQPSAVTWGIFPGREIIQPTVVDP 571
[87][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 124 bits (312), Expect = 3e-27
Identities = 68/152 (44%), Positives = 89/152 (58%), Gaps = 7/152 (4%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
SE+ V VF G + LPW + LA ET + LL +NR G++TINSQ
Sbjct: 426 SEESVFQVFAHHLSGEPNQNGYKVTCLPWND-EPLAAETSLMKEELLRVNRRGILTINSQ 484
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P +N PS+D VGWG GG+V+QKAY+EFF+S E +AL + +++ Y
Sbjct: 485 PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKG 544
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 545 ENITNAPELQPNAVTWGIFPGREIIQPTVVDP 576
[88][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 124 bits (311), Expect = 4e-27
Identities = 69/153 (45%), Positives = 90/153 (58%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
+R+ +G S +D+ +FVR+ + + LPW E S L E I L+ LN GL+TIN
Sbjct: 367 NRKKFGEPKSVKDIATLFVRYVQKEVDTLPWSE-SPLDAEAEQIRDDLIDLNLRGLITIN 425
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP VN ST GWG P G+VYQKAY+E P + + L + P LT YA
Sbjct: 426 SQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAV-TK 484
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
S L TN+ G NAVTWGVFP +EI+QPT+V+
Sbjct: 485 SGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVE 517
[89][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 124 bits (310), Expect = 5e-27
Identities = 71/172 (41%), Positives = 100/172 (58%), Gaps = 9/172 (5%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L + ++ A +++G + SE+ V +VF + R LPW + LA ET
Sbjct: 412 LKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNL 470
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
+ L +NR G++TINSQP +N PSTD VGWG GG+VYQKAY+EFF+S E AL
Sbjct: 471 LKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALL 530
Query: 365 KAAERF-PSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
K +++ P + + + L TN+ NAVTWG+F REI+QPT+VDP
Sbjct: 531 KVLKKYEPRVNYHIVNVHGRNL-TNAPDMQPNAVTWGIFAGREIVQPTVVDP 581
[90][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 124 bits (310), Expect = 5e-27
Identities = 71/172 (41%), Positives = 100/172 (58%), Gaps = 9/172 (5%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L + ++ A +++G + SE+ V +VF + R LPW + LA ET
Sbjct: 412 LKSKSSKEALLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWND-EPLAPETNL 470
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
+ L +NR G++TINSQP +N PSTD VGWG GG+VYQKAY+EFF+S E AL
Sbjct: 471 LKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALL 530
Query: 365 KAAERF-PSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
K +++ P + + + L TN+ NAVTWG+F REI+QPT+VDP
Sbjct: 531 KVLKKYEPRVNYHIVNVHGRNL-TNAPDMQPNAVTWGIFAGREIVQPTVVDP 581
[91][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 123 bits (309), Expect = 7e-27
Identities = 68/151 (45%), Positives = 94/151 (62%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FVR+ +G L RLPW + + +++E AI L+ LN G++TINSQ
Sbjct: 374 QLWGEPKSIKDLSRLFVRYLEGKLSRLPWSD-TPISSEAKAIKPNLIELNNRGILTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A S+ GWG GFVYQKAY+E P + D L E LT Y A + +
Sbjct: 433 PAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLT-YHAVSKNG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ NA+TWG+F RE++QPTIV+
Sbjct: 492 ELRTNTH-DSPNALTWGIFAGREVVQPTIVE 521
[92][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 123 bits (309), Expect = 7e-27
Identities = 68/151 (45%), Positives = 92/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ +FV F +G L RLPW + + + E AI L+ LN+ GL TINSQ
Sbjct: 374 KLWGEPKSLRDLTHIFVNFLEGKLARLPWSD-TPITTEANAIKTSLIDLNQKGLFTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG G+VYQKAY+E P + D L E+ LT Y A + +
Sbjct: 433 PAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLT-YHAVSKTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN++ NA+TWG+F REI+QPTIV+
Sbjct: 492 ELRTNTR-DSPNALTWGIFAGREIVQPTIVE 521
[93][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 123 bits (308), Expect = 9e-27
Identities = 66/151 (43%), Positives = 89/151 (58%), Gaps = 7/151 (4%)
Frame = +2
Query: 86 EQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQP 244
E+ V +VF + G + +PW + LA ET + L +NR G++TINSQP
Sbjct: 430 EESVFEVFTCYITGEPNKNGYKVTCMPWND-DPLATETNLLKDQLEKVNRRGILTINSQP 488
Query: 245 RVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKE 424
+N PSTD VGWG GG+V+QKAY+EFF+S E+ AL K +++ Y +
Sbjct: 489 NINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQ 548
Query: 425 LRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 549 NITNAPDLQPNAVTWGIFPGREIIQPTVVDP 579
[94][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 122 bits (305), Expect = 2e-26
Identities = 69/151 (45%), Positives = 88/151 (58%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ D+FV F G L RLPW + S + E I LL LN+ G +TINSQ
Sbjct: 374 KLWGEPKSIKDISDIFVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN S+ GWG GFVYQKAY+E + D L E+ LT Y A
Sbjct: 433 PAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLT-YHATNKKG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
EL+TN++ NA+TWG+F REIIQPTIV+
Sbjct: 492 ELKTNTR-DSPNALTWGIFAGREIIQPTIVE 521
[95][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 121 bits (304), Expect = 2e-26
Identities = 65/151 (43%), Positives = 88/151 (58%), Gaps = 7/151 (4%)
Frame = +2
Query: 86 EQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQP 244
E+ V +VF + G + +PW + LA ET + L +NR G++TINSQP
Sbjct: 287 EESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINSQP 345
Query: 245 RVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKE 424
+N PSTD GWG GG+V+QKAY+EFF+S E+ AL K +++ Y +
Sbjct: 346 NINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQ 405
Query: 425 LRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 406 NITNAPDLQPNAVTWGIFPGREIIQPTVVDP 436
[96][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 121 bits (304), Expect = 2e-26
Identities = 65/151 (43%), Positives = 88/151 (58%), Gaps = 7/151 (4%)
Frame = +2
Query: 86 EQDVVDVFVRFFKGSLKR-------LPWVEASELANETVAISAPLLWLNRNGLMTINSQP 244
E+ V +VF + G + +PW + LA ET + L +NR G++TINSQP
Sbjct: 419 EESVFEVFTCYITGEPNKNGHRVTCMPWND-DPLATETSLLKEQLEKVNRRGILTINSQP 477
Query: 245 RVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKE 424
+N PSTD GWG GG+V+QKAY+EFF+S E+ AL K +++ Y +
Sbjct: 478 NINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQ 537
Query: 425 LRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 538 NITNAPDLQPNAVTWGIFPGREIIQPTVVDP 568
[97][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 121 bits (304), Expect = 2e-26
Identities = 69/172 (40%), Positives = 99/172 (57%), Gaps = 9/172 (5%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L + + A +++G + SE+ V +VF + G R LPW + LA ET
Sbjct: 408 LKSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWND-DPLAPETNL 466
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
+ L +NR G++TINSQP +N S+D VGWG GG+V+QKAY+EFF+S E AL
Sbjct: 467 LKDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALL 526
Query: 365 KAAERF-PSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+ +++ P + + + TN+ NAVTWG+FP REIIQPT+VDP
Sbjct: 527 QVLKKYEPRVNYQIVNVQGRNI-TNAHDMQPNAVTWGIFPGREIIQPTVVDP 577
[98][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 121 bits (304), Expect = 2e-26
Identities = 65/151 (43%), Positives = 90/151 (59%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G + D+ + V + G L LPW + ++NE I +L LN G++TINSQ
Sbjct: 374 ELWGEPKTVDDLKTLLVNYLNGKLASLPWSDVP-ISNEIETIKPQILELNNRGILTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN A ST GWG G+VYQKAY+E +PE+ + L K E +T YA +
Sbjct: 433 PAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVN-KTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
L+TN+ G NAVTWG++P +E+IQPTIV+
Sbjct: 492 NLQTNA-PGGPNAVTWGIYPGKEVIQPTIVE 521
[99][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 121 bits (304), Expect = 2e-26
Identities = 66/151 (43%), Positives = 91/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++F+RF G L RLPW E + + ET I LL LN G +TINSQ
Sbjct: 374 QLWGKPKSLKELSEIFIRFLNGKLDRLPWSEGA-VTEETDIIKRDLLDLNSRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ S+ GWG G+VYQKAY+E SP + + + E+ LT Y +
Sbjct: 433 PAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVN-KTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ T NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELRTNT-TDSPNAVTWGIFVSKEIIQPTIVE 521
[100][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 121 bits (303), Expect = 3e-26
Identities = 68/163 (41%), Positives = 95/163 (58%)
Frame = +2
Query: 26 GLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLW 205
GL DA R L+G + +D+ +VF + + L LPW + L+ E+ I+ L
Sbjct: 372 GLKQTDAEI--RALWGSPENIRDLGNVFAAYCERKLACLPWSDIP-LSGESAIIADKLAE 428
Query: 206 LNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP 385
LNR G++TINSQP V AAPSTD GWG G+V+QKAY+EFF P+ +L + F
Sbjct: 429 LNRQGILTINSQPPVCAAPSTDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFK 488
Query: 386 SLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
++ Y + L TN + +AVTWGVFP E+IQPT+V+
Sbjct: 489 TVQYYITDYEG-SLETNGELDVPSAVTWGVFPNSEVIQPTVVE 530
[101][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 120 bits (300), Expect = 7e-26
Identities = 65/151 (43%), Positives = 91/151 (60%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++F+RF G L RLPW E + + ET I LL LN G +TINSQ
Sbjct: 374 QLWGKPKSLKELSEIFIRFLNGKLDRLPWSEGA-VTEETDIIKRDLLDLNSRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ S+ GWG G+VYQKAY+E SP + + + E+ LT Y +
Sbjct: 433 PAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVN-KTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ + NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELRTNT-SDSPNAVTWGIFVSKEIIQPTIVE 521
[102][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 118 bits (296), Expect = 2e-25
Identities = 66/154 (42%), Positives = 88/154 (57%), Gaps = 1/154 (0%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
S EL+ + D+ + + + KG LK LPW + L E A+ L+ LN + ++TIN
Sbjct: 385 SLELWSTPRTLLDLAALVISYLKGDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTIN 443
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKA-AERFPSLTVYAAKA 412
SQP+VN APS D VGWG G+VYQK Y+EF A A FP+LT +A A
Sbjct: 444 SQPKVNGAPSADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDA 503
Query: 413 DSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
D + ANAVTWG+FP RE++QPTIV+
Sbjct: 504 DDNLASNHPDDTQANAVTWGIFPGREVLQPTIVE 537
[103][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 118 bits (295), Expect = 3e-25
Identities = 64/151 (42%), Positives = 90/151 (59%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +++ ++F+ F G L RLPW E + + ET I LL LN G +TINSQ
Sbjct: 374 QLWGKPKSLKELSEIFIHFLNGKLDRLPWSEGA-VTEETDIIKRDLLDLNSRGFLTINSQ 432
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P ++ S+ GWG G+VYQKAY+E SP + + + E+ LT Y +
Sbjct: 433 PAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVN-KTG 491
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
ELRTN+ + NAVTWG+F +EIIQPTIV+
Sbjct: 492 ELRTNT-SDSPNAVTWGIFVSKEIIQPTIVE 521
[104][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 117 bits (293), Expect = 5e-25
Identities = 65/159 (40%), Positives = 92/159 (57%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ ++ V + K LK LPW + + +T I L+ LN+ G +T+NSQ
Sbjct: 119 DLWGCPQSFKDLSNLVVSYLKNDLKSLPWSDGP-IGEDTAIIVDKLISLNQRGFLTMNSQ 177
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS--------LTV 397
P +N S D GWG G+V+QK Y+EFF ++ L ++ E+F LT
Sbjct: 178 PSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTY 237
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
YAA + EL TN+K NAVTWGVFP EI+QPTIV+
Sbjct: 238 YAADKNG-ELNTNTKEDDINAVTWGVFPGEEILQPTIVE 275
[105][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 117 bits (293), Expect = 5e-25
Identities = 65/159 (40%), Positives = 92/159 (57%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S +D+ ++ V + K LK LPW + + +T I L+ LN+ G +T+NSQ
Sbjct: 119 DLWGCPQSFKDLSNLVVSYLKNDLKSLPWSDGP-IGEDTAIIVDKLISLNQRGFLTMNSQ 177
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS--------LTV 397
P +N S D GWG G+V+QK Y+EFF ++ L ++ E+F LT
Sbjct: 178 PSLNCVKSNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTY 237
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
YAA + EL TN+K NAVTWGVFP EI+QPTIV+
Sbjct: 238 YAADKNG-ELNTNTKEDDINAVTWGVFPGEEILQPTIVE 275
[106][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 117 bits (293), Expect = 5e-25
Identities = 61/149 (40%), Positives = 90/149 (60%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S ++ D+F R+ + + LPW + +++E I LL +NRN +TINSQP
Sbjct: 379 WGSPKSYSEIGDLFARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFLTINSQPA 437
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
+N S+ GWG P G+V+QK YVEFF P + + L + ++ S++ + + +L
Sbjct: 438 LNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNG-DL 496
Query: 428 RTNSKTPGANAVTWGVFPEREIIQPTIVD 514
TNS+ NAVTWGVFP REIIQPTIV+
Sbjct: 497 DTNSQYEIPNAVTWGVFPNREIIQPTIVE 525
[107][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 117 bits (292), Expect = 6e-25
Identities = 64/159 (40%), Positives = 88/159 (55%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G S D+ + + + KG LK LPW + + ++T I L++LN++G T+NSQ
Sbjct: 379 ELWGLPQSLADLSGIIINYLKGDLKSLPWSDGP-VGDDTRVIVDDLIYLNQHGFFTMNSQ 437
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL--------FKAAERFPSLTV 397
P +NA S++ GWG G+VYQK Y+EFF ++ L K AE +
Sbjct: 438 PALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFIS 497
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A L TN K NAVTWGVFP EI+QPTIV+
Sbjct: 498 YYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVE 536
[108][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 116 bits (290), Expect = 1e-24
Identities = 64/156 (41%), Positives = 84/156 (53%), Gaps = 5/156 (3%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G + D+ D+ V + +K LPW + + +T + L+ LNR GL T+NSQ
Sbjct: 381 ELWGCPQTLNDLSDIIVSYLNNEVKALPWSDGP-IGEDTTVLKDALIALNRKGLFTLNSQ 439
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS-----LTVYAA 406
P ++A S D GWG GFVYQK Y+EF + L E+ + L Y A
Sbjct: 440 PALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYA 499
Query: 407 KADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
S L TNSK NAVTWGVFP EI+QPTIV+
Sbjct: 500 VDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVE 535
[109][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 115 bits (289), Expect = 1e-24
Identities = 63/159 (39%), Positives = 88/159 (55%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G S ++ + + + KG LK LPW + + ++T I L++LN++G T+NSQ
Sbjct: 379 ELWGLPQSLAELSGIIINYLKGDLKSLPWSDGP-VGDDTKVIVDDLIYLNQHGFFTMNSQ 437
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF--------KAAERFPSLTV 397
P +NA S++ GWG G+VYQK Y+EFF ++ L K AE +
Sbjct: 438 PALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAFIS 497
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A L TN K NAVTWGVFP EI+QPTIV+
Sbjct: 498 YYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVE 536
[110][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 115 bits (289), Expect = 1e-24
Identities = 62/159 (38%), Positives = 92/159 (57%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G GS +++ D+ + + KG LK LPW + S + ++T I L+ LN+ GL+T+NSQ
Sbjct: 380 ELWGTPGSLKELSDIVISYLKGDLKSLPWSDGS-VGDDTKVIVDDLVELNKRGLLTMNSQ 438
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF--------PSLTV 397
P +N+ S++ GWG G+VYQK Y+EFF ++ L + + + ++
Sbjct: 439 PALNSIKSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIIS 498
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A L TN NAVTWGVFP EI+QPTIV+
Sbjct: 499 YYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVE 537
[111][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 115 bits (288), Expect = 2e-24
Identities = 65/168 (38%), Positives = 91/168 (54%)
Frame = +2
Query: 11 LVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAIS 190
L+GS + + RA EL+ D+ + + + G LK LPW + + L +E
Sbjct: 369 LLGSTSIRQSPQRAL--ELWSTPTKFSDIAALVIDYLHGKLKCLPWCDVA-LNHEVDTTM 425
Query: 191 APLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKA 370
LL LN++ ++T+NSQPRVN A S D VGWG G+VYQK Y+EF L
Sbjct: 426 PQLLDLNKHMILTLNSQPRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLSQLRDF 485
Query: 371 AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
PSLT +A + + + ANAVTWG+FP RE++QPTIV+
Sbjct: 486 VNDMPSLTYFAVDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVE 533
[112][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 114 bits (285), Expect = 4e-24
Identities = 59/152 (38%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
E++G S D+ +F+R+ +GSL+ LPW + L+ ET I L+ LN G +++ SQ
Sbjct: 449 EIWGQPSSTDDIKTLFIRYLEGSLEALPWSDLG-LSAETALIQEELIQLNERGYLSLASQ 507
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFK-AAERFPSLTVYAAKADS 418
P N+ PSTD GWG PGG+VYQK++VE F + + K E S Y +
Sbjct: 508 PATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVHKQQWELEIKPKLEPLGSKVSYYVGDSA 567
Query: 419 KELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ TN + ++ VTWGVFP E++Q TIV+
Sbjct: 568 ETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVE 599
[113][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 113 bits (282), Expect = 9e-24
Identities = 61/159 (38%), Positives = 87/159 (54%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G G+ + D+ + F G L LPW + S + ++ I L+ LN+ G T+NSQ
Sbjct: 379 DLWGHPGTLKQFSDIIISFLSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQ 437
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF--------PSLTV 397
P +NA S D GWG G+VYQK Y+EFF ++ AL + + S+
Sbjct: 438 PSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLT 497
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A +L +N+K NAVTWGVFP EI+QPTIV+
Sbjct: 498 YYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVE 536
[114][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 113 bits (282), Expect = 9e-24
Identities = 61/159 (38%), Positives = 87/159 (54%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G G+ + D+ + F G L LPW + S + ++ I L+ LN+ G T+NSQ
Sbjct: 379 DLWGHPGTLKQFSDIIISFLSGKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQ 437
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF--------PSLTV 397
P +NA S D GWG G+VYQK Y+EFF ++ AL + + S+
Sbjct: 438 PSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLT 497
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A +L +N+K NAVTWGVFP EI+QPTIV+
Sbjct: 498 YYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVE 536
[115][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 113 bits (282), Expect = 9e-24
Identities = 62/154 (40%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S D+ D+F+R +G L +PW E L ET +I LL LN+ G T+ SQ
Sbjct: 450 KLWGHPSSRADITDIFIRHLEGQLTAIPWSEEG-LNEETNSIKKQLLSLNKKGWWTVASQ 508
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF---SSPEMTDALFKAAERFPSLTVYAAKA 412
P VN STD GWG GFV+QKA+VE F S E A + +++ YA+ A
Sbjct: 509 PAVNGVKSTDSIFGWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNA 568
Query: 413 DSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ++ NAVTWG FP +EII PTI++
Sbjct: 569 KGDFISSDEAIGSTNAVTWGAFPGKEIITPTIIE 602
[116][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 112 bits (281), Expect = 1e-23
Identities = 66/154 (42%), Positives = 86/154 (55%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
S +L+G E D+ ++F R G +PW++ A ET I L L T+
Sbjct: 415 SLKLWGYPVDEDDITNIFKRHVLGETTAIPWIDQPVEA-ETKTIGDKLAKLIEKKWWTVG 473
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP VNAAPS+ GWG GG+V+QKA+VE F S +AL + P +T Y A +
Sbjct: 474 SQPAVNAAPSSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQIT-YLAGNN 532
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
E +TN+ ANAVTWGVFP REIIQ TI+ P
Sbjct: 533 KGEFKTNASLDSANAVTWGVFPGREIIQSTIIAP 566
[117][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 112 bits (281), Expect = 1e-23
Identities = 61/153 (39%), Positives = 88/153 (57%), Gaps = 2/153 (1%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S D+ VF+++ +GS+ LPW + L+ ET I L+ LN+ G +T+ SQ
Sbjct: 433 DLWGTPKSVIDLKSVFIKYLEGSISALPWCDLG-LSPETALIQEELIQLNQRGYLTLASQ 491
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFK-AAERFP-SLTVYAAKAD 415
P NA+PSTD GWG G+VYQKA+VE F + +A+ K + +P Y
Sbjct: 492 PATNASPSTDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDS 551
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
S +N +T +N VTWGVFP +IQ TIV+
Sbjct: 552 SGSFESNLETNSSNVVTWGVFPNSPVIQTTIVE 584
[118][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 112 bits (280), Expect = 2e-23
Identities = 64/150 (42%), Positives = 84/150 (56%), Gaps = 7/150 (4%)
Frame = +2
Query: 89 QDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+DV VF + G +K LP + EL ET +S L +N +G +T NSQP
Sbjct: 407 EDVYHVFQCYLSGKKNKWGYKVKSLP-LNDDELQPETSLLSDQLYRINGHGFLTTNSQPA 465
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
VNAA STD GWGG GG++YQKAY+EFF + D L + P + + +
Sbjct: 466 VNAALSTDERFGWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYD 525
Query: 428 RTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
+TN+ AVTWGVFP +EIIQPT+VDP
Sbjct: 526 KTNADRYSPIAVTWGVFPGKEIIQPTVVDP 555
[119][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 112 bits (279), Expect = 2e-23
Identities = 60/159 (37%), Positives = 87/159 (54%), Gaps = 8/159 (5%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + +D D+ V + +G LK LPW + + +T + L+ LN G +T+NSQ
Sbjct: 379 DLWGTPQTLKDFSDIIVSYLQGELKSLPWSDGP-IGEDTSVMVENLINLNHKGFLTMNSQ 437
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF--------PSLTV 397
P +NA S++ GWG G+VYQK Y+EFF ++ L + + S+
Sbjct: 438 PALNAVKSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIIS 497
Query: 398 YAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A + L TN K NAVTWGVFP EI+QPTIV+
Sbjct: 498 YYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVE 536
[120][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 110 bits (275), Expect = 6e-23
Identities = 67/172 (38%), Positives = 92/172 (53%), Gaps = 9/172 (5%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L + A+ R L+G + SE DV VF F G++ PW + L+ ET
Sbjct: 381 LRSRTAKDKLRSLWGKELTSEADVWKVFKHFITGAVNENGVKVTETPWNDDG-LSPETNV 439
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
+S+ L N G++TINSQP VNA PST GWG GG++ QKAY+EFF + +AL
Sbjct: 440 LSSTLSRYNELGVLTINSQPNVNAVPSTHPIYGWGDKGGYISQKAYLEFFINKHYAEALK 499
Query: 365 KAAERF-PSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVDP 517
++ P + + TN+ NAVTWG+F +EIIQPT+VDP
Sbjct: 500 TVLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVTWGIFAGKEIIQPTVVDP 551
[121][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 110 bits (274), Expect = 8e-23
Identities = 64/163 (39%), Positives = 90/163 (55%), Gaps = 12/163 (7%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + QD+ D+FV+ +G L +PW E EL E+ I LL LN+ G T+ SQ
Sbjct: 452 KLWGHPKTRQDINDLFVKHIQGQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQ 510
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF---SSPEMTDALFKAAERFPSLTVYAAKA 412
P VN S+D + GWG P GFV+QK++VEFF S + ++E S+ YA A
Sbjct: 511 PAVNGLRSSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNA 570
Query: 413 DSKELR---------TNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ++ P NAVTWGVFP +EII PTI++
Sbjct: 571 KGDFVSSDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIE 613
[122][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 110 bits (274), Expect = 8e-23
Identities = 59/154 (38%), Positives = 86/154 (55%), Gaps = 3/154 (1%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G S D+ D+F+R +G L +PW E L ET +I LL LN+ G T+ SQ
Sbjct: 450 KLWGHPSSRADITDIFIRHLEGQLTAIPWSEEG-LNEETNSIKKQLLSLNKKGWWTVASQ 508
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF---SSPEMTDALFKAAERFPSLTVYAAKA 412
P VN S+D GWG GFV+QKA+VE F + + A + + +++ YA+ A
Sbjct: 509 PAVNGLKSSDSIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNA 568
Query: 413 DSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ++ NAVTWG FP +EII PTI++
Sbjct: 569 KGDFISSDEAVGSTNAVTWGAFPGKEIITPTIIE 602
[123][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 108 bits (271), Expect = 2e-22
Identities = 60/154 (38%), Positives = 83/154 (53%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMT 229
A + EL+G + D+ +F G L +PW + + L+ ET+ I L+ LN+ G+ T
Sbjct: 410 ARALELWGYPVDDADLSKLFADTIVGKLPFMPWSDQT-LSPETMLIQEQLMELNQKGIWT 468
Query: 230 INSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAK 409
+ SQP NA S D GWG GG+V+QK++ EFF SPE L + L Y
Sbjct: 469 VASQPACNALKSDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVA 528
Query: 410 ADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
K + TN +N VTWGVFP REI+Q TI+
Sbjct: 529 KSDKLVDTNVSERASNGVTWGVFPNREIVQTTII 562
[124][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 108 bits (270), Expect = 2e-22
Identities = 62/156 (39%), Positives = 88/156 (56%), Gaps = 12/156 (7%)
Frame = +2
Query: 83 SEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAP 262
+ QD+ D+FV+ +G L +PW E EL E+ I LL LN G T+ SQP VN
Sbjct: 457 TRQDINDLFVKHIQGELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLR 515
Query: 263 STDMSVGWGGPGGFVYQKAYVEFF---SSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
S+D + GWG P GFV+QK++VEFF + E+ A ++E + YA+ A + +
Sbjct: 516 SSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSS 575
Query: 434 N---------SKTPGANAVTWGVFPEREIIQPTIVD 514
+ +P NAVTWGVFP +EII PTI++
Sbjct: 576 DIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIE 611
[125][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 108 bits (270), Expect = 2e-22
Identities = 54/119 (45%), Positives = 73/119 (61%)
Frame = +2
Query: 158 SELANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFS 337
S L NE I L+ LN+ G++TINSQP VN S+ GWG G+VYQK+Y+E
Sbjct: 113 SPLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLV 172
Query: 338 SPEMTDALFKAAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
P++ + E+ P +T YA S L+ N+ + G NAVTWGVFP +EI+QPTIV+
Sbjct: 173 HPDLYPEIISRIEKHPDMTYYAV-TKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVE 230
[126][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 108 bits (270), Expect = 2e-22
Identities = 62/151 (41%), Positives = 87/151 (57%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G E D+ +F + + +PW++ + ET I+ LL LN N T+ SQ
Sbjct: 430 KLWGYPVDESDITSLFQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQ 488
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVE-FFSSPEMTDALFKAAERFPSLTVYAAKADS 418
P VN APS D GWG GG V+QKA+VE F + ++ D + K + P +T YA +
Sbjct: 489 PAVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDN-PQVTYYAGN-NK 546
Query: 419 KELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
E TN+ GA+AVTWGV+P REIIQ TI+
Sbjct: 547 SEFLTNAPKDGASAVTWGVYPGREIIQSTII 577
[127][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 107 bits (268), Expect = 4e-22
Identities = 59/151 (39%), Positives = 84/151 (55%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+ S DV + + + G+LK LPW + + + +E I A L+ LN++ ++TINSQ
Sbjct: 386 ELWSTPTSINDVAFLVINYLNGNLKCLPWSDIT-INDEINPIKAHLIELNQHSIITINSQ 444
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P+VN S D GWG G+VYQK Y+EF L + LT +A +
Sbjct: 445 PQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGD 504
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
L + +NAVTWG+FP REI+QPTIV+
Sbjct: 505 LLSNHPDNSKSNAVTWGIFPGREILQPTIVE 535
[128][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 107 bits (268), Expect = 4e-22
Identities = 58/161 (36%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
++EL+G + D+ + + + KG L LPW + + + +T I L+ LN N L+T+N
Sbjct: 377 AQELWGLPQTISDITGLVISYLKGQLNSLPWFDGA-IGEDTNIILDHLIELNENSLITLN 435
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF--------PSL 391
SQP +N+ S+D GWG G+VYQK Y+EFF ++ L +++ ++
Sbjct: 436 SQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAV 495
Query: 392 TVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
Y A + L +N + NAVTWGVFP EI+QPTIV+
Sbjct: 496 ISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVE 536
[129][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 107 bits (268), Expect = 4e-22
Identities = 61/173 (35%), Positives = 88/173 (50%), Gaps = 7/173 (4%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAP 196
G G + A + +G + +D+ +F+ + G + +PW + + L+ ET I
Sbjct: 403 GYGPTLKIHSPAEAEIKWGSPETTKDLAQIFIDYLSGKIDVIPWADQA-LSPETALIQEE 461
Query: 197 LLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAE 376
L LN G ++ SQP NA STD GWG G VYQKA+VE F + + L E
Sbjct: 462 LFQLNEKGWFSVASQPAANACKSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVE 521
Query: 377 RFPSLTVYAAKADSKELRTNSKTPGA-------NAVTWGVFPEREIIQPTIVD 514
S+T YAA K + +K P NAVTWGVFP +E++QPT++D
Sbjct: 522 ASDSITYYAA---DKTNKIEAKVPAGHDIKLTKNAVTWGVFPSKEVLQPTVID 571
[130][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 107 bits (266), Expect = 6e-22
Identities = 59/151 (39%), Positives = 83/151 (54%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+ S DV + + + G+LK LPW + + +E I A L+ LN++ ++TINSQ
Sbjct: 197 ELWSTPTSINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQ 255
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P+VN S D GWG G+VYQK Y+EF L + LT +A +
Sbjct: 256 PQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGD 315
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
L + +NAVTWG+FP REI+QPTIV+
Sbjct: 316 LLSNHPDNSKSNAVTWGIFPGREILQPTIVE 346
[131][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 107 bits (266), Expect = 6e-22
Identities = 59/151 (39%), Positives = 83/151 (54%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+ S DV + + + G+LK LPW + + +E I A L+ LN++ ++TINSQ
Sbjct: 386 ELWSTPTSINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQ 444
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P+VN S D GWG G+VYQK Y+EF L + LT +A +
Sbjct: 445 PQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGD 504
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
L + +NAVTWG+FP REI+QPTIV+
Sbjct: 505 LLSNHPDNSKSNAVTWGIFPGREILQPTIVE 535
[132][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 107 bits (266), Expect = 6e-22
Identities = 59/151 (39%), Positives = 83/151 (54%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+ S DV + + + G+LK LPW + + +E I A L+ LN++ ++TINSQ
Sbjct: 386 ELWSTPTSINDVAFLVINYLNGNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQ 444
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P+VN S D GWG G+VYQK Y+EF L + LT +A +
Sbjct: 445 PQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGD 504
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
L + +NAVTWG+FP REI+QPTIV+
Sbjct: 505 LLSNHPDNSKSNAVTWGIFPGREILQPTIVE 535
[133][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 106 bits (264), Expect = 1e-21
Identities = 62/158 (39%), Positives = 86/158 (54%), Gaps = 7/158 (4%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G S +D+ VFV++ +GS++ LPW + L+ ET I L+ LN G +T+ SQ
Sbjct: 433 ELWGSPTSIRDLKAVFVKYLEGSIQSLPWCDLG-LSPETALIQEELIQLNYRGYLTLASQ 491
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAK---- 409
P NA+ STD GWG G VYQKA++E F + + K P L Y +
Sbjct: 492 PCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILK-----PKLDYYGRRKFSY 546
Query: 410 --ADSK-ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
DSK TN +N VTWGVFP ++IQ TI++
Sbjct: 547 YAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIE 584
[134][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 106 bits (264), Expect = 1e-21
Identities = 58/153 (37%), Positives = 83/153 (54%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
S EL+ S +D+ + + + +G LK LPW + S L +E I L+ LN+ ++TIN
Sbjct: 383 SLELWSAPNSMEDIAQLVINYLRGELKYLPWSDTS-LNHEVDDILPELVTLNQKLIITIN 441
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP++N S+ GWG G+VYQK Y+EF E L LT +A +
Sbjct: 442 SQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHN 501
Query: 416 SKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ANAVTWG+FP RE++QPTIV+
Sbjct: 502 GNLTTNHQDGTRANAVTWGIFPGREVLQPTIVE 534
[135][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 105 bits (263), Expect = 1e-21
Identities = 63/154 (40%), Positives = 84/154 (54%), Gaps = 1/154 (0%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
S EL+ + D+ ++ + +G LK LPW + L +E I L+ LN++ + TIN
Sbjct: 386 SIELWSTPQTLDDMSNLVTSYLEGKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIFTIN 444
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP+VN PSTD VGWG G+VYQK Y+EF E + + Y A
Sbjct: 445 SQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDS 504
Query: 416 SKELRTN-SKTPGANAVTWGVFPEREIIQPTIVD 514
L TN + ANAVTWGVFP EI+QPTIV+
Sbjct: 505 QDNLATNHPEDSRANAVTWGVFPGSEILQPTIVE 538
[136][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 105 bits (262), Expect = 2e-21
Identities = 59/171 (34%), Positives = 86/171 (50%), Gaps = 5/171 (2%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAP 196
G G A + +G S D+ VF+ + G + +PW ++S L+ ET I
Sbjct: 410 GYGPTLKIHTPAEASTKWGTPESIADLTQVFINYLSGKVDVVPWADSS-LSPETALIQEE 468
Query: 197 LLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAE 376
L LN G ++ SQP VN STD GWG G +YQK+++E F E L E
Sbjct: 469 LFQLNEKGWFSVASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIE 528
Query: 377 RFPSLTVYAAKADSKELRTN-----SKTPGANAVTWGVFPEREIIQPTIVD 514
++T Y D E+++N + NAVTWGVFP +E++QPT++D
Sbjct: 529 LDKTVTYYVGNKDG-EIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVID 578
[137][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 105 bits (262), Expect = 2e-21
Identities = 59/171 (34%), Positives = 86/171 (50%), Gaps = 5/171 (2%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAP 196
G G A + +G S D+ VF+ + G + +PW ++S L+ ET I
Sbjct: 410 GYGPTLKIHTPAEASTKWGTPESIADLTQVFINYLSGKVDVVPWADSS-LSPETALIQEE 468
Query: 197 LLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAE 376
L LN G ++ SQP VN STD GWG G +YQK+++E F E L E
Sbjct: 469 LFQLNEKGWFSVASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIE 528
Query: 377 RFPSLTVYAAKADSKELRTN-----SKTPGANAVTWGVFPEREIIQPTIVD 514
++T Y D E+++N + NAVTWGVFP +E++QPT++D
Sbjct: 529 LDKTVTYYVGNKDG-EIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVID 578
[138][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 105 bits (261), Expect = 2e-21
Identities = 59/154 (38%), Positives = 89/154 (57%), Gaps = 4/154 (2%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+G + QD+ +F+++ +GS+ LPW + L+ ET I L+ LN G +T+ SQ
Sbjct: 437 ELWGQPKTIQDLQIIFIKYLEGSIDALPWCDLG-LSPETALIQEELIQLNERGFLTLASQ 495
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTD--ALFKAAERF--PSLTVYAAK 409
P N +PST+ GWG G VYQKA++E F + + + KA E++ LT YA
Sbjct: 496 PATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQYGRAKLTYYAND 555
Query: 410 ADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
+ TN ++ +N VTWGVF + ++IQ TIV
Sbjct: 556 SQG-NFETNLESNSSNVVTWGVFSDSQVIQSTIV 588
[139][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 104 bits (260), Expect = 3e-21
Identities = 55/152 (36%), Positives = 83/152 (54%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+++G + D+ +F+ + +GS++ LPW + L+ ET I L+ LN+ G +T+ SQ
Sbjct: 424 QIWGYPSTLNDIKSLFIGYLEGSIEALPWCDLG-LSPETALIQEELIGLNQRGFLTLASQ 482
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFP-SLTVYAAKADS 418
P N+ PS D GWG PGG VYQKA+VE F +A K P S Y +
Sbjct: 483 PATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSA 542
Query: 419 KELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+N ++ VTWGVFP +I+Q TI++
Sbjct: 543 GSFASNMAPESSSVVTWGVFPNSQILQTTIIE 574
[140][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 104 bits (260), Expect = 3e-21
Identities = 58/154 (37%), Positives = 83/154 (53%), Gaps = 5/154 (3%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S D+ VF+ + G + +PW ++S L+ ET I L LN G ++ SQP
Sbjct: 427 WGTPESLADLTRVFINYLSGKVDVIPWADSS-LSPETALIQEELFQLNEKGWFSVASQPA 485
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
+N STD GWG G +YQK+++E F E L E ++T Y D E+
Sbjct: 486 INGCKSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDG-EI 544
Query: 428 RTNSKT-PGA----NAVTWGVFPEREIIQPTIVD 514
R+N P A NAVTWGVFP +E++QPT++D
Sbjct: 545 RSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVID 578
[141][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 104 bits (259), Expect = 4e-21
Identities = 58/152 (38%), Positives = 85/152 (55%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
EL+ S +D+ ++F+R+ +GS+K LPW + L+ ET I L+ LN+ G +++ SQ
Sbjct: 438 ELWDHPVSLEDIKNIFIRYLEGSMKALPWSDLG-LSAETAFIQEELIELNQRGYLSLASQ 496
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFK-AAERFPSLTVYAAKADS 418
P N + STD GWG G +YQKA+VE F E + + K E Y +
Sbjct: 497 PATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYT 556
Query: 419 KELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
TN + +NAVTWGVFP E++Q TIV+
Sbjct: 557 GYFETNLQPKSSNAVTWGVFPNSEVVQTTIVE 588
[142][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 104 bits (259), Expect = 4e-21
Identities = 57/154 (37%), Positives = 86/154 (55%), Gaps = 4/154 (2%)
Frame = +2
Query: 65 LYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQP 244
++G S DV VF+ + + LPWV ++EL+ ET I L LN GL T+ SQP
Sbjct: 388 VWGTPQSVADVSRVFIDYLSAKISSLPWV-STELSPETALIQEQLFELNSRGLFTLASQP 446
Query: 245 RVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS--LTVYAAKADS 418
V++ PS+D +GWG G ++QK++VEFF + L + ++ S Y
Sbjct: 447 AVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSK 506
Query: 419 KELRTN--SKTPGANAVTWGVFPEREIIQPTIVD 514
E+ TN K+ A+TWGVFP +E++QPT++D
Sbjct: 507 GEITTNMPHKSSQRTAITWGVFPSKEVLQPTVID 540
[143][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 103 bits (258), Expect = 5e-21
Identities = 63/155 (40%), Positives = 87/155 (56%), Gaps = 2/155 (1%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
S EL+ + +DV + + + G +K LPW + S L E I LL LNR ++TIN
Sbjct: 384 SLELWSTPKTIEDVSQLVISYLTGQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMIITIN 442
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKAD 415
SQP++N S GWG G+VYQK Y+EF E + L K LT +A D
Sbjct: 443 SQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFA--VD 500
Query: 416 SKELRTNSKTPG--ANAVTWGVFPEREIIQPTIVD 514
+K+ ++ G ANAVTWG+FP RE++QPTIV+
Sbjct: 501 NKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVE 535
[144][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 102 bits (253), Expect = 2e-20
Identities = 57/161 (35%), Positives = 88/161 (54%), Gaps = 12/161 (7%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S +++ VFV + G + LPWV+A+ L+ ET I L +N G ++ SQP
Sbjct: 424 WGAPESVNEIIKVFVSYLSGKIDSLPWVDAA-LSPETALIQEELFEVNNKGWFSLASQPA 482
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPE-MTDALFKAAERF---PSLTVYAAKAD 415
VN S+D GWG G +YQKA++E F + T+ L +++ ++T Y A+
Sbjct: 483 VNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAE 542
Query: 416 SK--------ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ + NSK NA+TWGVFP +E++QPTI+D
Sbjct: 543 GRLTSNLNIDQEHYNSK----NAITWGVFPSKEVLQPTIID 579
[145][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 101 bits (252), Expect = 3e-20
Identities = 61/157 (38%), Positives = 85/157 (54%), Gaps = 8/157 (5%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S +D+ VF+ + G + LPWV+A L+ ET I L LN G ++ SQP
Sbjct: 426 WGTPESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPS 484
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPE--MTDALFKAAERFPSLTV-YAAKADS 418
VN A S+D GWG GFV+QK++VE F E T K +L + Y A S
Sbjct: 485 VNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSS 544
Query: 419 KELRTN-----SKTPGANAVTWGVFPEREIIQPTIVD 514
++++N NAVTWGVFP +E++QPTI+D
Sbjct: 545 GKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIID 581
[146][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 101 bits (252), Expect = 3e-20
Identities = 59/157 (37%), Positives = 83/157 (52%), Gaps = 8/157 (5%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S D+ VF+ + G + LPW ++S L+ ET I L LN G ++ SQP
Sbjct: 419 WGSPESVGDIAKVFMGYLSGKIDILPWTDSS-LSAETTLIQEELFDLNDRGWFSLASQPA 477
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAER----FPSLTVYAAKAD 415
VN STD GWG G VYQKA+VE F E ++ K++ + ++T Y A+
Sbjct: 478 VNGCKSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESELKSSLKPHFEEKTITYYVGDAE 537
Query: 416 SKELRTNSKTPGA----NAVTWGVFPEREIIQPTIVD 514
P A NA+TWGVFP +E++QPTI+D
Sbjct: 538 GNIESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIID 574
[147][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 100 bits (250), Expect = 5e-20
Identities = 57/161 (35%), Positives = 88/161 (54%), Gaps = 12/161 (7%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S +++ VFV + G + LPWV+A+ L+ ET I L +N G ++ SQP
Sbjct: 424 WGAPESVNEIIKVFVSYLSGKIDSLPWVDAA-LSPETALIQEELFEVNNKGWFSLASQPA 482
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPE-MTDALFKAAERF---PSLTVYAAKAD 415
VN S+D GWG G +YQKA++E F + T+ L +++ ++T Y A+
Sbjct: 483 VNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAE 542
Query: 416 SK--------ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ + NSK NA+TWGVFP +E++QPTI+D
Sbjct: 543 GRLTSNLNIDQEHYNSK----NAITWGVFPLKEVLQPTIID 579
[148][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 100 bits (249), Expect = 6e-20
Identities = 61/157 (38%), Positives = 85/157 (54%), Gaps = 8/157 (5%)
Frame = +2
Query: 68 YGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPR 247
+G S +D+ VF+ + G + LPWV+A L+ ET I L LN G ++ SQP
Sbjct: 426 WGTPESTKDISKVFLNYLSGKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPS 484
Query: 248 VNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPE--MTDALFKAAERFPSLTV-YAAKADS 418
VN A S+D GWG GFV+QK++VE F E T K +L + Y A S
Sbjct: 485 VNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSS 544
Query: 419 KELRTN-----SKTPGANAVTWGVFPEREIIQPTIVD 514
++++N NAVTWGVFP +E++QPTI+D
Sbjct: 545 GKIQSNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIID 581
[149][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 100 bits (249), Expect = 6e-20
Identities = 62/155 (40%), Positives = 85/155 (54%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMT 229
A +R+L+G S D+ +F+R +G L+ +PW E S A ET I L+ LN G T
Sbjct: 447 AQARQLWGAPVSPPDISAIFIRHLRGELQTIPWSEESFSA-ETDKIRDQLVALNSKGWWT 505
Query: 230 INSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAK 409
+ SQP VN S+D + GWG GFV+QKA+VEFF AL K R +
Sbjct: 506 LASQPAVNGLRSSDPTFGWGPQNGFVFQKAFVEFFLPLADWAALEKRLNR--------PE 557
Query: 410 ADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ + R S NAV+WGVFP +EI+ PTI++
Sbjct: 558 MEGRREREAS----TNAVSWGVFPGKEIVPPTIIE 588
[150][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 100 bits (248), Expect = 8e-20
Identities = 62/175 (35%), Positives = 88/175 (50%), Gaps = 24/175 (13%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + +D+ +F+R KG L +PW E +ET AI L+ LN G ++ SQ
Sbjct: 447 QLWGSPKTTEDINKIFIRHLKGELSAIPWSEEG-FNDETEAIRDNLIELNSRGWWSLASQ 505
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF-------------SSPEMTDAL------- 361
P VN S D + GWG GFV+QKA+VEFF P+M D +
Sbjct: 506 PAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNA 565
Query: 362 ---FKAAERFPSLTVYAAKAD-SKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
F + + AA+A+ + E P NAVTWGVFP +EI+ PTI++
Sbjct: 566 AGDFVSTDTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIE 620
[151][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 99.4 bits (246), Expect = 1e-19
Identities = 58/151 (38%), Positives = 80/151 (52%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G ++D+ +F R +G L+ +PW E L+ ET ISA LL LN G T+ SQ
Sbjct: 445 KLWGYPVEKKDISTLFRRHIEGDLEAIPWSEQG-LSPETSTISAQLLALNAKGWWTVASQ 503
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN STD GWG G+V+QK +VEFF A + +T +A A
Sbjct: 504 PAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAG- 562
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
S+ G N VTWG F +EI+ PTI++
Sbjct: 563 -AFEASQEDGVNPVTWGTFAGKEIVTPTIIE 592
[152][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 99.0 bits (245), Expect = 2e-19
Identities = 61/161 (37%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Frame = +2
Query: 65 LYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQP 244
L+G S D+ +F++ +G L +PW E L+ ET I L+ LN G T+ SQP
Sbjct: 450 LWGHPKSSVDISTLFIKHIRGELSAIPWSEEG-LSPETNIIQEQLIELNTRGWWTVASQP 508
Query: 245 RVNAAPSTDMSVGWGGPGGFVYQKAYVEFF--------SSPEMTDALFKAAERFPSLT-- 394
VN PS D + GWG GFV+QKA+VE F S +T + F +
Sbjct: 509 AVNGVPSRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGN 568
Query: 395 -VYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+A DS L + NAVTWGVFP +EII PTI++
Sbjct: 569 GDFATSDDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIE 609
[153][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 99.0 bits (245), Expect = 2e-19
Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 7/157 (4%)
Frame = +2
Query: 65 LYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNR------NGLM 226
L+G E D+ +F RF G L +PW + + +ET+ + LL LN
Sbjct: 371 LWGTPVDEDDISSIFSRFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWW 429
Query: 227 TINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS-LTVYA 403
T+ SQP V+ STD + G+G GG+++QKA+VE F + +AL + + + +T +A
Sbjct: 430 TVGSQPAVDGCDSTDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFA 489
Query: 404 AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
K D TN T G N VTWGVFP E+ Q TI++
Sbjct: 490 GKCDPTTFETNLTTNGLNTVTWGVFPGTEVAQSTIIE 526
[154][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 98.6 bits (244), Expect = 2e-19
Identities = 61/168 (36%), Positives = 88/168 (52%), Gaps = 13/168 (7%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMT 229
A + ++G + +D+ +VF+R KG L +PW E + ET I L+ LN G +
Sbjct: 465 AQALRIWGTPRTTEDINNVFIRHLKGELTTIPWSEEG-FSPETDKIRDQLIKLNSKGWWS 523
Query: 230 INSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSL----TV 397
+ SQP VN S+D + GWG GFV+QKA+VEFF P + + R P L
Sbjct: 524 LASQPAVNGLRSSDPTFGWGPANGFVFQKAFVEFF-IPSADWKVLEQKLRHPDLKDDVCF 582
Query: 398 YAAKADSKELRTNS---------KTPGANAVTWGVFPEREIIQPTIVD 514
YA A + +++ K NAVTWGVFP +EI+ PTI++
Sbjct: 583 YAINAAGDFVSSDTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIE 630
[155][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 97.8 bits (242), Expect = 4e-19
Identities = 57/151 (37%), Positives = 82/151 (54%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G +QD+ +F + +G L+ LPW E L+ ET I+ LL LN G T+ SQ
Sbjct: 335 KLWGHPVDKQDISALFRKHLEGELEALPWSEQG-LSPETSTIAKQLLALNAKGWWTVASQ 393
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSK 421
P VN STD GWG G+V+QK +VEFF AL + +T +A A+
Sbjct: 394 PAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANG- 452
Query: 422 ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ +S+ N VTWG F +EI+ PTI++
Sbjct: 453 DFEASSE-ESVNPVTWGTFAGKEIVTPTIIE 482
[156][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 96.7 bits (239), Expect = 9e-19
Identities = 62/158 (39%), Positives = 83/158 (52%), Gaps = 5/158 (3%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLM-TI 232
S EL+ S +DV + V + +G L+ LPW + + +++E I L+ LN L+ TI
Sbjct: 378 SLELWAMPSSIRDVAMLVVAYLQGELRCLPWSD-TPVSSEVDVIRRQLIALNEQQLIVTI 436
Query: 233 NSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFF----SSPEMTDALFKAAERFPSLTVY 400
NSQP+VN S GWG G+VYQK Y+EF + L K E SLT
Sbjct: 437 NSQPQVNGLRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYL 496
Query: 401 AAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
AA + A AVTWGVFP RE++QPTIV+
Sbjct: 497 AADSHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVE 534
[157][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 96.7 bits (239), Expect = 9e-19
Identities = 64/176 (36%), Positives = 87/176 (49%), Gaps = 25/176 (14%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G + +DV ++F+R +G+L +PW E E ET I LL LN G T+ SQ
Sbjct: 430 QLWGRPATVEDVSNIFMRHLRGALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVASQ 488
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL-FKAAERFPSLTVYAAK--- 409
P VN S D + GWG GFV+QKA+VE F + AL K + YA+
Sbjct: 489 PAVNGLRSNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKG 548
Query: 410 ---------------------ADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
AD + L + S T NAVTWGVFP +EI+ PTI++
Sbjct: 549 DFESSDGGGDAPDGAPTGNGFADEQPLPSGSST---NAVTWGVFPGKEIVTPTIIE 601
[158][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 96.3 bits (238), Expect = 1e-18
Identities = 55/152 (36%), Positives = 81/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 62 ELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQ 241
+L+G D+ +F+ + + LPW E L ET I L+ LN + TI+SQ
Sbjct: 384 KLWGYPVDLDDITKIFIAYLSNRITALPWSELG-LNPETGLIQEELIQLNEKHMFTISSQ 442
Query: 242 PRVNAAPSTDMSVGWGGPGGFVYQKAYVE-FFSSPEMTDALFKAAERFPSLTVYAAKADS 418
P N STD GWG G+VYQKA+VE F + + + + + S+T Y ++
Sbjct: 443 PSANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNN 502
Query: 419 KELRTNSKTP-GANAVTWGVFPEREIIQPTIV 511
TN K P +N+VTWG FP++EI+Q TI+
Sbjct: 503 -AFDTNIKIPLSSNSVTWGCFPDKEIVQTTII 533
[159][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 95.9 bits (237), Expect = 1e-18
Identities = 60/163 (36%), Positives = 88/163 (53%), Gaps = 13/163 (7%)
Frame = +2
Query: 65 LYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNR---------- 214
++G S D+ +F + + + +PW +A L NET+ I LL LNR
Sbjct: 463 IWGHPVSLTDISRIFGFYLEEKISCIPWCDAP-LMNETLQIRDHLLTLNRLAENASQSAG 521
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPS-- 388
G ++ SQP V+ APSTD VG+G PGGFV+QK++VE F S D L + +
Sbjct: 522 KGWWSVGSQPAVDGAPSTDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASA 581
Query: 389 -LTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+T +A A + ++N AN VTW VFP +EI+Q TI++
Sbjct: 582 PITYFAGNAKG-DFQSNLGDEEANTVTWAVFPGKEIVQSTIIE 623
[160][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 93.2 bits (230), Expect = 1e-17
Identities = 45/96 (46%), Positives = 62/96 (64%)
Frame = +2
Query: 140 LPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKA 319
LPW + ELA ET I L+ N NG+++INSQP VNAA STD +GWGG GG++YQKA
Sbjct: 4 LPWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKA 62
Query: 320 YVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKEL 427
Y+EFF+SPE+ L + + +P + + + L
Sbjct: 63 YLEFFASPEVVYILLQELKNYPQVNYHVVNNHLRNL 98
[161][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 92.0 bits (227), Expect = 2e-17
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
+++ + EL+G + D+ D+F+++ +GS +PW + L+ ET I L+ LN G
Sbjct: 437 SKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLG-LSAETALIQEELIQLNYRGY 495
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+T+ SQP NA S+D GWG G +YQKA+VE F + + K P L Y
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLK-----PKLDHYG 550
Query: 404 -------AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
A S TN ++ VTWGVFP + Q TI++
Sbjct: 551 RRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIE 594
[162][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 92.0 bits (227), Expect = 2e-17
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
+++ + EL+G + D+ D+F+++ +GS +PW + L+ ET I L+ LN G
Sbjct: 437 SKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLG-LSAETALIQEELIQLNYRGY 495
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+T+ SQP NA S+D GWG G +YQKA+VE F + + K P L Y
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLK-----PKLDHYG 550
Query: 404 -------AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
A S TN ++ VTWGVFP + Q TI++
Sbjct: 551 RRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIE 594
[163][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 92.0 bits (227), Expect = 2e-17
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
+++ + EL+G + D+ D+F+++ +GS +PW + L+ ET I L+ LN G
Sbjct: 437 SKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLG-LSAETALIQEELIQLNYRGY 495
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+T+ SQP NA S+D GWG G +YQKA+VE F + + K P L Y
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLK-----PKLDHYG 550
Query: 404 -------AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
A S TN ++ VTWGVFP + Q TI++
Sbjct: 551 RRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIE 594
[164][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 92.0 bits (227), Expect = 2e-17
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGL 223
+++ + EL+G + D+ D+F+++ +GS +PW + L+ ET I L+ LN G
Sbjct: 437 SKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLG-LSAETALIQEELIQLNYRGY 495
Query: 224 MTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYA 403
+T+ SQP NA S+D GWG G +YQKA+VE F + + K P L Y
Sbjct: 496 LTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLK-----PKLDHYG 550
Query: 404 -------AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
A S TN ++ VTWGVFP + Q TI++
Sbjct: 551 RRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIE 594
[165][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 91.3 bits (225), Expect = 4e-17
Identities = 59/174 (33%), Positives = 87/174 (50%), Gaps = 3/174 (1%)
Frame = +2
Query: 2 NHHLVGSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETV 181
N L G G++ +D A + S D+ +F+ + P+ + L++E++
Sbjct: 369 NQDLWGGSGISGSDVLAQ----WNNPKSLDDLTQIFLGHLHAKILTTPF-SPTPLSSESL 423
Query: 182 AISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL 361
I L L R T+ SQP V+ S D VGWG GG+V+QK +VEFF + D +
Sbjct: 424 MILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVI 483
Query: 362 FKAAERFPSLTVYAAKADSK---ELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ER V+ + K E R+N G NAVTWGVFP +EI Q TI++
Sbjct: 484 ERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIE 537
[166][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 90.5 bits (223), Expect = 6e-17
Identities = 48/109 (44%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Frame = +2
Query: 77 IGSEQDVVDVFVRFFKGS-------LKRLPWVEASELANETVAISAPLLWLNRNGLMTIN 235
+ SE+ V +VF + G + LPW + LA ET + + L +N+ G++TIN
Sbjct: 419 LSSEESVFEVFTYYISGEPNPNGHKVTCLPWND-DPLAPETNLLKSELQKVNKRGILTIN 477
Query: 236 SQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERF 382
SQP VN PSTD VGWG G+V+QKAY+EFF+S EM AL K +R+
Sbjct: 478 SQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRY 526
[167][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 90.5 bits (223), Expect = 6e-17
Identities = 65/172 (37%), Positives = 92/172 (53%), Gaps = 6/172 (3%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRL--PWVEASELANETVAIS 190
G G A A +E P+ S D+ +F + K L P+ + L+ E+ I
Sbjct: 401 GWGSGLKITAAQALKEWGVPV-STSDLSALFTAYLHSDPKHLTTPFCDLP-LSPESHMIL 458
Query: 191 APLLWLNRNGLM--TINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALF 364
LL LN + T+ SQP V+AA S D VGWG GG+V+QKA+VEFF + + + L
Sbjct: 459 PHLLALNSANVQHWTVGSQPAVDAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLK 518
Query: 365 KAAERFPS--LTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+ ER +T+YAA + +TN+ NAVTWGVFP +EI Q TI++
Sbjct: 519 EKVEREGKGLITMYAANRKG-DFKTNTDKDSVNAVTWGVFPGQEIAQSTIIE 569
[168][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 90.5 bits (223), Expect = 6e-17
Identities = 55/147 (37%), Positives = 75/147 (51%), Gaps = 5/147 (3%)
Frame = +2
Query: 89 QDVVDVFVRFFKGSLKRLPWVEASELANETVAISAPLLWLNRNGLMTINSQPRVNAAPST 268
+++ VFV + G + +PW + S L+ ET I L LN+ G ++ SQP VN S
Sbjct: 419 KELGQVFVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQPAVNGCRSN 477
Query: 269 DMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELR----TN 436
D GWG G VYQK++VE F + L R T Y S + TN
Sbjct: 478 DNVFGWGPGNGVVYQKSFVELFIPAKDWKEL---KPRLDDATTYYVGDKSGRIELSLFTN 534
Query: 437 SKTPG-ANAVTWGVFPEREIIQPTIVD 514
T NAVTWGVFP +E++QPT++D
Sbjct: 535 ESTRHLKNAVTWGVFPLKEVVQPTVID 561
[169][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 89.7 bits (221), Expect = 1e-16
Identities = 66/187 (35%), Positives = 90/187 (48%), Gaps = 34/187 (18%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANETVAISAPLLWL-NR 214
+R L+G S +D+ +F R G+L +PW E L ET I LL L ++
Sbjct: 444 ARRLWGFPTSREDINQIFRRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDK 503
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK-------- 367
G T+ SQP VN S D + GWG PG GFV+QKA+VEFF S + K
Sbjct: 504 RGWWTLASQPAVNGVRSDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGH 563
Query: 368 ---------AAERFPSLTVYAAKADSKELRTNSKTP---------GANAVTWGVFPEREI 493
AA F + T +A + ++ + + P G NAVTWGVF +EI
Sbjct: 564 DEFAWFATNAAGDFEASTPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEI 623
Query: 494 IQPTIVD 514
I PTI++
Sbjct: 624 ITPTIIE 630
[170][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 88.6 bits (218), Expect = 2e-16
Identities = 56/167 (33%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASELANETVAISAP 196
G GGL +RA + + +G + D+ +F+ + P+ +EL E++ I
Sbjct: 387 GPGGL--GISRAEALQQWGYPKTFDDLTRIFLAHLHSEIPITPF-SPTELCPESITILPH 443
Query: 197 LLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDAL-FKAA 373
L L + G T+ SQP V+ S+D + GWG G+V+QK +VEFF +A+ +
Sbjct: 444 LERLTKRGWWTVGSQPAVDGISSSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIK 503
Query: 374 ERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
+R Y ++ E R+N G NAVTWGVFP +EI Q TI++
Sbjct: 504 QRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIE 550
[171][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 88.2 bits (217), Expect = 3e-16
Identities = 44/88 (50%), Positives = 56/88 (63%)
Frame = +2
Query: 254 AAPSTDMSVGWGGPGGFVYQKAYVEFFSSPEMTDALFKAAERFPSLTVYAAKADSKELRT 433
A PS+D VGWG GG+V+QKAY+EFF+S E +AL + + + Y E T
Sbjct: 1 AKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENIT 60
Query: 434 NSKTPGANAVTWGVFPEREIIQPTIVDP 517
N+ NAVTWG+FP REIIQPT+VDP
Sbjct: 61 NAPELQPNAVTWGIFPGREIIQPTVVDP 88
[172][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 87.4 bits (215), Expect = 5e-16
Identities = 65/181 (35%), Positives = 87/181 (48%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE------ASELANETVAISAPLLWL- 208
A +R ++G S +D+ +F R G L +PW E +S L ET I LL L
Sbjct: 465 AVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLI 524
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ G T+ SQP VN S D + GWG PG GFV+QK +VEFF + + K
Sbjct: 525 DSKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKH 584
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
E SL A AD+ E+ N+ NAVTWGVF +EI+ PTI+
Sbjct: 585 GHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNN----VNAVTWGVFRGKEIVTPTII 640
Query: 512 D 514
+
Sbjct: 641 E 641
[173][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 86.3 bits (212), Expect = 1e-15
Identities = 65/181 (35%), Positives = 87/181 (48%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE------ASELANETVAISAPLLWL- 208
A +R ++G S +D+ +F R G L +PW E +S L ET I LL L
Sbjct: 438 AVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLI 497
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ G T+ SQP VN S D + GWG PG GFV+QK +VEFF + + K
Sbjct: 498 DGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKH 557
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
E SL A AD+ E+ N+ NAVTWGVF +EI+ PTI+
Sbjct: 558 GHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNN----VNAVTWGVFRGKEIVTPTII 613
Query: 512 D 514
+
Sbjct: 614 E 614
[174][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 84.7 bits (208), Expect = 3e-15
Identities = 65/187 (34%), Positives = 89/187 (47%), Gaps = 34/187 (18%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANETVAISAPLLWL-NR 214
+R L+G + +D+ ++F + G L +PW E L+ ET+ I LL L +
Sbjct: 446 ARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEK 505
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK-------- 367
G TI SQP V+ S GWG PG GFV+QKA+VEFF S + + K
Sbjct: 506 RGWWTIASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGH 565
Query: 368 ---------AAERFPSLTVYA---------AKADSKELRTNSKTPGANAVTWGVFPEREI 493
AA F S T + A D + +S + G NAVTWGVF +EI
Sbjct: 566 DEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEI 625
Query: 494 IQPTIVD 514
I PTI++
Sbjct: 626 ITPTIIE 632
[175][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 84.3 bits (207), Expect = 4e-15
Identities = 64/181 (35%), Positives = 86/181 (47%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE------ASELANETVAISAPLLWL- 208
A +R ++G S +D+ +F G L +PW E +S L ET I LL L
Sbjct: 438 AVARRIWGYPVSREDISALFRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLI 497
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ G T+ SQP VN S D + GWG PG GFV+QK +VEFF + + K
Sbjct: 498 DGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKH 557
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
E SL A AD+ E+ N+ NAVTWGVF +EI+ PTI+
Sbjct: 558 GHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNN----VNAVTWGVFRGKEIVTPTII 613
Query: 512 D 514
+
Sbjct: 614 E 614
[176][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 84.0 bits (206), Expect = 6e-15
Identities = 64/187 (34%), Positives = 89/187 (47%), Gaps = 34/187 (18%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANETVAISAPLLWL-NR 214
+R L+G + +D+ ++F + G L +PW E L+ ET+ I LL L +
Sbjct: 446 ARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEK 505
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK-------- 367
G T+ SQP V+ S GWG PG GFV+QKA+VEFF S + + K
Sbjct: 506 RGWWTLASQPAVSGVRSDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGH 565
Query: 368 ---------AAERFPSLTVYA---------AKADSKELRTNSKTPGANAVTWGVFPEREI 493
AA F S T + A D + +S + G NAVTWGVF +EI
Sbjct: 566 DEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEI 625
Query: 494 IQPTIVD 514
I PTI++
Sbjct: 626 ITPTIIE 632
[177][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 82.4 bits (202), Expect = 2e-14
Identities = 64/178 (35%), Positives = 85/178 (47%), Gaps = 25/178 (14%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA------SELANETVAISAPLLWL-NR 214
+R ++G S D+ +F R G L +PW E S L ET I LL L +
Sbjct: 441 ARRVWGYPVSRDDISTLFRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDG 500
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK-------- 367
G T+ SQP VN S + + GWG PG GFV+QK +VEFF + + + K
Sbjct: 501 KGWWTLASQPAVNGVRSDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGH 560
Query: 368 ---------AAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
A F S ++ A ADS L N NAVTWGVF +EI+ PTI++
Sbjct: 561 EKLAWFATNAKGEFQS-SLPAETADSDALEPNPDN--VNAVTWGVFRGKEIVTPTIIE 615
[178][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 81.3 bits (199), Expect = 4e-14
Identities = 61/181 (33%), Positives = 84/181 (46%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE------ASELANETVAISAPLLWL- 208
A + ++G S +D+ +F R G L +PW E +S L ET I LL L
Sbjct: 438 AVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLI 497
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ NG T+ SQP VN S D GWG P GFV+QK +VEFF + ++ K
Sbjct: 498 DGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH 557
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
+ SL + AD E+ N+ N VTWGVF +EI+ PTI+
Sbjct: 558 GHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNN----VNCVTWGVFRGKEIVTPTII 613
Query: 512 D 514
+
Sbjct: 614 E 614
[179][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 81.3 bits (199), Expect = 4e-14
Identities = 63/182 (34%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Frame = +2
Query: 44 ARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEA------SELANETVAISAPLLW 205
A + + ++G S D+ +F R G L +PW E S L ET I LL
Sbjct: 432 APSVAHRIWGYPVSTDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLA 491
Query: 206 L-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK---- 367
L ++ G T+ SQP VN S D GWG PG GFV+QK +VEFF K
Sbjct: 492 LIDKKGWWTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQ 551
Query: 368 -------------AAERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTI 508
AA F S ++ A +D++ + N NAVTWGVF +EI+ PTI
Sbjct: 552 KHGHEKLAWFATNAAGDFES-SLPAETSDTEPVEMNPNN--VNAVTWGVFRGKEIVTPTI 608
Query: 509 VD 514
++
Sbjct: 609 IE 610
[180][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 81.3 bits (199), Expect = 4e-14
Identities = 61/181 (33%), Positives = 84/181 (46%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE------ASELANETVAISAPLLWL- 208
A + ++G S +D+ +F R G L +PW E +S L ET I LL L
Sbjct: 486 AVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLI 545
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ NG T+ SQP VN S D GWG P GFV+QK +VEFF + ++ K
Sbjct: 546 DGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH 605
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
+ SL + AD E+ N+ N VTWGVF +EI+ PTI+
Sbjct: 606 GHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNN----VNCVTWGVFRGKEIVTPTII 661
Query: 512 D 514
+
Sbjct: 662 E 662
[181][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 81.3 bits (199), Expect = 4e-14
Identities = 61/178 (34%), Positives = 85/178 (47%), Gaps = 23/178 (12%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE--ASELAN----ETVAISAPLLWL- 208
A +R ++G + +D+ +F R G L +PW E A E +N ET I LL L
Sbjct: 447 ATARRIWGYPVTREDISTLFRRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLI 506
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKAAERFP 385
++ G T+ SQP +N S D GWG PG GFV+QK +VEFF + + K +
Sbjct: 507 DKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKH 566
Query: 386 SLTVYAAKADSKELRTNSKTPG---------------ANAVTWGVFPEREIIQPTIVD 514
A A + + S PG NAVTWGVF +EI+ PTI++
Sbjct: 567 GHEKLAWFATNVKGDFESSLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIE 624
[182][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 79.3 bits (194), Expect = 1e-13
Identities = 66/195 (33%), Positives = 90/195 (46%), Gaps = 29/195 (14%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANET 178
G G + +A A R+L+G S++D+ +F G L +PW E L ET
Sbjct: 436 GYGPSLHVNANVA-RQLWGYPTSKEDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAET 494
Query: 179 VAISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMT 352
I LL L + G T+ SQP VN S GWG G GFV+QKA+VEFF S +
Sbjct: 495 ATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDF 554
Query: 353 DALFKAAERF---PSLTVYAAKADSKELRTNSKTP------------------GANAVTW 469
+ + K + L+ +A A ++S T G NAVTW
Sbjct: 555 EKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGITGLDDAVPDYNGAASSNGVNAVTW 614
Query: 470 GVFPEREIIQPTIVD 514
GVF +EII PTI++
Sbjct: 615 GVFKGKEIITPTIIE 629
[183][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 79.0 bits (193), Expect = 2e-13
Identities = 66/195 (33%), Positives = 89/195 (45%), Gaps = 29/195 (14%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANET 178
G G + +A A R+L+G S +D+ +F G L +PW E L ET
Sbjct: 436 GYGPSLHVNANVA-RQLWGYPTSREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAET 494
Query: 179 VAISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMT 352
I LL L + G T+ SQP VN S GWG G GFV+QKA+VEFF S +
Sbjct: 495 ATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDF 554
Query: 353 DALFKAAERF---PSLTVYAAKADSKELRTNSKTP------------------GANAVTW 469
+ + K + L+ +A A ++S T G NAVTW
Sbjct: 555 EKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDAVPDYNGAASSNGVNAVTW 614
Query: 470 GVFPEREIIQPTIVD 514
GVF +EII PTI++
Sbjct: 615 GVFKGKEIITPTIIE 629
[184][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 79.0 bits (193), Expect = 2e-13
Identities = 66/195 (33%), Positives = 89/195 (45%), Gaps = 29/195 (14%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANET 178
G G + +A A R+L+G S +D+ +F G L +PW E L ET
Sbjct: 436 GYGPSLHVNANVA-RQLWGYPTSREDINKLFHCHVSGELHIVPWSEGGSAEDSGGLNAET 494
Query: 179 VAISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMT 352
I LL L + G T+ SQP VN S GWG G GFV+QKA+VEFF S +
Sbjct: 495 ATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVFQKAFVEFFCSGQDF 554
Query: 353 DALFKAAERF---PSLTVYAAKADSKELRTNSKTP------------------GANAVTW 469
+ + K + L+ +A A ++S T G NAVTW
Sbjct: 555 EKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDAVPDYSGAASSNGVNAVTW 614
Query: 470 GVFPEREIIQPTIVD 514
GVF +EII PTI++
Sbjct: 615 GVFKGKEIITPTIIE 629
[185][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 79.0 bits (193), Expect = 2e-13
Identities = 63/188 (33%), Positives = 85/188 (45%), Gaps = 33/188 (17%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE-----LANETVAISAPLLWL-N 211
A +R L+G ++QD+ ++F R G L +PW E L ET I LL L N
Sbjct: 443 AVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLIN 502
Query: 212 RNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK------- 367
G T+ SQP VN + GWG G GFV+QKA+VEFF +++ K
Sbjct: 503 GRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHS 562
Query: 368 ----------AAERFPSLT--VYAAKADSK-------ELRTNSKTPGANAVTWGVFPERE 490
AA F S + A DS + + G AVTWGVF +E
Sbjct: 563 HDEFAWFATNAAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKE 622
Query: 491 IIQPTIVD 514
I+ PTI++
Sbjct: 623 IVTPTIIE 630
[186][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 78.6 bits (192), Expect = 2e-13
Identities = 61/188 (32%), Positives = 83/188 (44%), Gaps = 33/188 (17%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE-----LANETVAISAPLLWL-N 211
A +R L+G ++QD+ ++F R G L +PW E L ET I LL L N
Sbjct: 442 AVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLIN 501
Query: 212 RNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKAAERFPS 388
G T+ SQP VN + GWG G GFV+QKA+VEFF +++ K S
Sbjct: 502 GRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHS 561
Query: 389 LTVYAAKADSKELRTNSKTP--------------------------GANAVTWGVFPERE 490
+A A + S +P G AVTWGVF +E
Sbjct: 562 HDEFAWFATNAAGDFMSSSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKE 621
Query: 491 IIQPTIVD 514
I+ PTI++
Sbjct: 622 IVTPTIIE 629
[187][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 78.2 bits (191), Expect = 3e-13
Identities = 61/188 (32%), Positives = 83/188 (44%), Gaps = 33/188 (17%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE-----LANETVAISAPLLWL-N 211
A +R L+G ++QD+ ++F R G L +PW E L ET I LL L N
Sbjct: 443 AVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLIN 502
Query: 212 RNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKAAERFPS 388
G T+ SQP VN + GWG G GFV+QKA+VEFF +++ K S
Sbjct: 503 GRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHS 562
Query: 389 LTVYAAKADSKELRTNSKTP--------------------------GANAVTWGVFPERE 490
+A A + S +P G AVTWGVF +E
Sbjct: 563 HDEFAWFATNVAGDFMSSSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKE 622
Query: 491 IIQPTIVD 514
I+ PTI++
Sbjct: 623 IVTPTIIE 630
[188][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 77.8 bits (190), Expect = 4e-13
Identities = 62/188 (32%), Positives = 84/188 (44%), Gaps = 33/188 (17%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE-----LANETVAISAPLLWL-N 211
A +R L+G +++D+ +F R G L +PW E L ET I LL L N
Sbjct: 443 AVARRLWGYPTTKEDINTIFQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLIN 502
Query: 212 RNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFK------- 367
G T+ SQP VN + GWG G GFV+QKA+VEFF + + K
Sbjct: 503 GRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHG 562
Query: 368 ----------AAERFPSLTV--------YAAKAD-SKELRTNSKTPGANAVTWGVFPERE 490
AA F S + Y+ D + + G NAVTWGVF +E
Sbjct: 563 HDELAWFATNAAGDFESSSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKE 622
Query: 491 IIQPTIVD 514
I+ PTI++
Sbjct: 623 IVTPTIIE 630
[189][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 77.4 bits (189), Expect = 5e-13
Identities = 68/205 (33%), Positives = 88/205 (42%), Gaps = 39/205 (19%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE-----LANETV 181
G G + AR A R+L+G S +D+ ++F R G L +PW E L ET
Sbjct: 394 GYGPSLHVTARVA-RKLWGTPTSREDISNIFRRLLSGELHAVPWSEGGAGEEGGLNPETA 452
Query: 182 AISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTD 355
I LL L G T+ SQP VN + GWG G GFV+QKA+VEFF +
Sbjct: 453 TIRTELLKLVEGRGWWTLASQPSVNGVRNDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFH 512
Query: 356 ALFKAAERFPSLTVYA----------AKADSKELR---------TNSKTP---------- 448
+ K P L Y AK D + T+S P
Sbjct: 513 SKLK-----PLLNSYGHDEFAWFAMNAKGDFQSSTSPEPPASPPTDSTEPLFDTDPLTDM 567
Query: 449 ---GANAVTWGVFPEREIIQPTIVD 514
NAVTWGVF +EI+ PTI++
Sbjct: 568 DNGSVNAVTWGVFRGKEIVTPTIIE 592
[190][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 75.1 bits (183), Expect = 3e-12
Identities = 58/181 (32%), Positives = 79/181 (43%), Gaps = 26/181 (14%)
Frame = +2
Query: 50 AASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANETVAISAPLLWL- 208
+ + ++G + D+ +F R G L +PW E L ET I LL L
Sbjct: 446 SVAHRIWGYPVTRDDINTLFRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLI 505
Query: 209 NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFFSSPEMTDALFKA----- 370
+ G T+ SQP VN S D GWG P GFV+QK +VEFF + K
Sbjct: 506 DGKGWWTLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKH 565
Query: 371 -------------AERFPSLTVYAAKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIV 511
+ SL + AD E+ N+ NAVTWGVF +EI+ PTI+
Sbjct: 566 GHEKLAWFATNANGDFESSLPAQTSDADPIEMNPNN----VNAVTWGVFRGKEIVTPTII 621
Query: 512 D 514
+
Sbjct: 622 E 622
[191][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 73.2 bits (178), Expect = 1e-11
Identities = 65/202 (32%), Positives = 90/202 (44%), Gaps = 36/202 (17%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE--ASELAN---ETV 181
G G + +A A ++L+G + +D+ +F + G L +PW E A+E AN ET
Sbjct: 438 GYGPSLHVNATVA-KQLWGFPVTREDIGALFRKHVSGELYIVPWSEGGAAEDANLNAETE 496
Query: 182 AISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFF------- 334
I LL + + T+ SQP VN S GWG PG GFV+QKA+VEFF
Sbjct: 497 TIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQ 556
Query: 335 ----------SSPEMTDALFKAAERFPSLTVYAAKADSKELRTNSKTPGAN--------- 457
S E + AA S + + + K T+S A+
Sbjct: 557 NKVKPTLLKHGSEEFSWFAINAAGHLESSFLISTSSSPKPEDTSSAVAAADEEPLEIRES 616
Query: 458 ---AVTWGVFPEREIIQPTIVD 514
AVTWG F REI PTI++
Sbjct: 617 TGMAVTWGAFRGREITTPTIIE 638
[192][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 72.4 bits (176), Expect = 2e-11
Identities = 62/179 (34%), Positives = 84/179 (46%), Gaps = 26/179 (14%)
Frame = +2
Query: 56 SRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVEASE------LANETVAISAPLLWL-NR 214
+R L+G +D+ +F R G L +PW E L ET I LL L +
Sbjct: 439 ARRLWGHPVDSKDMSAIFRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDG 498
Query: 215 NGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFF-SSPEMTDAL--FKAAERF 382
G T+ SQP VN + GWG GFV+QK +VEFF SS + T+ L A
Sbjct: 499 RGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGH 558
Query: 383 PSLTVYA---------------AKADSKELRTNSKTPGANAVTWGVFPEREIIQPTIVD 514
LT +A A D +L +N ++ NAVTWGVF +EI+ PTI++
Sbjct: 559 DKLTWFATNVKGDFESSLPAQPADMDLDDLGSNPES--VNAVTWGVFRGKEIVTPTIIE 615
[193][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 70.1 bits (170), Expect = 9e-11
Identities = 64/201 (31%), Positives = 88/201 (43%), Gaps = 35/201 (17%)
Frame = +2
Query: 17 GSGGLTNADARAASRELYGPIGSEQDVVDVFVRFFKGSLKRLPWVE--ASELAN---ETV 181
G G + +A A +EL+G + +D+ +F + G L +PW E A+E AN ET
Sbjct: 436 GYGPSLHVNATVA-KELWGFPVTREDIGTLFRKHVSGELYIVPWSEGGAAEDANLNAETQ 494
Query: 182 AISAPLLWL-NRNGLMTINSQPRVNAAPSTDMSVGWGGPG-GFVYQKAYVEFF------- 334
I LL + + T+ SQP VN S GWG PG GFV+QKA+VEFF
Sbjct: 495 IIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQKAFVEFFCPNADYQ 554
Query: 335 ----------SSPEMTDALFKAAERFPSLTVYAAKADSKELRTNS-----------KTPG 451
S E + A S + +A + K +S +
Sbjct: 555 NKVKPTLLKHGSEEFSWFAINATGHLESSFLLSASSSPKPEDASSTIAADEEPVEVRESK 614
Query: 452 ANAVTWGVFPEREIIQPTIVD 514
AVTWG F REI PTI++
Sbjct: 615 GMAVTWGAFRGREITTPTIIE 635
[194][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 69.7 bits (169), Expect = 1e-10
Identities = 41/104 (39%), Positives = 58/104 (55%), Gaps = 8/104 (7%)
Frame = +2
Query: 29 LTNADARAASRELYGP-IGSEQDVVDVFVRFFKGSLKR-------LPWVEASELANETVA 184
L + ++ A +++G + SE+ V +VF + R LPW + LA ET
Sbjct: 412 LKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWND-EPLAQETNL 470
Query: 185 ISAPLLWLNRNGLMTINSQPRVNAAPSTDMSVGWGGPGGFVYQK 316
+ L +NR G++TINSQP +N PSTD VGWG GG+VYQK
Sbjct: 471 LKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQK 514