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[1][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 73.6 bits (179), Expect = 7e-12
Identities = 48/126 (38%), Positives = 65/126 (51%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 181
FRT+NAS+TL LQ GET + +A Y + NK VA LCNH R++ GH QM++LE +
Sbjct: 455 FRTYNASITLDNLLQDTTGETTIEIIADYQRANKQVAILCNHQRSVSKGHSAQMERLEGK 514
Query: 182 RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQER 361
E ++EL+ L + KG K S V+ Q PE LE A K +
Sbjct: 515 MQELEEQLEELETDLDRAKKGKPPLK---DSEGKVKRNQ----TPEALEKKIAATKQKID 567
Query: 362 KRAADL 379
K D+
Sbjct: 568 KMRLDM 573
[2][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 72.0 bits (175), Expect = 2e-11
Identities = 47/126 (37%), Positives = 62/126 (49%), Gaps = 1/126 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H QM +L
Sbjct: 730 FRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNE 789
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ E A V+ELK L++ KG K+ A P + PE LE A A+
Sbjct: 790 KIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKR-----NLNPESLEKKIAQTNAKI 844
Query: 359 RKRAAD 376
K D
Sbjct: 845 EKMERD 850
[3][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 70.5 bits (171), Expect = 6e-11
Identities = 35/81 (43%), Positives = 50/81 (61%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLETR 181
FRT+NAS+TL LQ GET + +A Y + NK VA LCNH R++ GH QM++LE +
Sbjct: 325 FRTYNASITLDTLLQDTRGETTIEIIADYQRANKEVAILCNHQRSVSKGHSAQMERLELK 384
Query: 182 RAEAVAWVKELKRGLAKWNKG 244
E ++EL+ L + +G
Sbjct: 385 MQELEEQLEELETDLDRAKRG 405
[4][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/139 (34%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q++KL
Sbjct: 333 FRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTA 392
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT---QYMPVKPEILESMTADEK 349
R E +KELK L + KG PP+E + + ++P E A +
Sbjct: 393 RIEELKEVLKELKTNLDRAKKG----------KPPLEGSDGKKIRSLEPNAWEKKIAQQS 442
Query: 350 AQERKRAADLPKVPLLKSM 406
A+ K D+ LK++
Sbjct: 443 AKIEKMERDMHTKEDLKTV 461
[5][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/139 (34%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q++KL
Sbjct: 215 FRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTA 274
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT---QYMPVKPEILESMTADEK 349
R E +KELK L + KG PP+E + + ++P E A +
Sbjct: 275 RIEELKEVLKELKTNLDRAKKG----------KPPLEGSDGKKIRSLEPNAWEKKIAQQS 324
Query: 350 AQERKRAADLPKVPLLKSM 406
A+ K D+ LK++
Sbjct: 325 AKIEKMERDMHTKEDLKTV 343
[6][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/139 (34%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q++KL
Sbjct: 89 FRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTA 148
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT---QYMPVKPEILESMTADEK 349
R E +KELK L + KG PP+E + + ++P E A +
Sbjct: 149 RIEELKEVLKELKTNLDRAKKG----------KPPLEGSDGKKIRSLEPNAWEKKIAQQS 198
Query: 350 AQERKRAADLPKVPLLKSM 406
A+ K D+ LK++
Sbjct: 199 AKIEKMERDMHTKEDLKTV 217
[7][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 70.1 bits (170), Expect = 7e-11
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H QM +L
Sbjct: 748 FRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNE 807
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSP-----PVEVTQYMPVKPEILESMTAD 343
+ E ++ELK L++ KG AK GA P P + + + +E M D
Sbjct: 808 KIDELKTALEELKTDLSRAKKGKPPAK-GADGEPKRNLNPESLERKIAQTNAKIEKMERD 866
Query: 344 EKAQERKRAADL 379
+K +E +A L
Sbjct: 867 KKTKEDLKAVAL 878
[8][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 70.1 bits (170), Expect = 7e-11
Identities = 48/139 (34%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + VT K+ Y K NK VA +CNH RT+ H Q++KL
Sbjct: 735 FRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTA 794
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT---QYMPVKPEILESMTADEK 349
R E +KELK L + KG PP+E + + ++P E A +
Sbjct: 795 RIEELKEVLKELKTNLDRAKKG----------KPPLEGSDGKKIRSLEPNAWEKKIAQQS 844
Query: 350 AQERKRAADLPKVPLLKSM 406
A+ K D+ LK++
Sbjct: 845 AKIEKMERDMHTKEDLKTV 863
[9][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 68.2 bits (165), Expect = 3e-10
Identities = 46/139 (33%), Positives = 66/139 (47%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + G +K+ Y NK VA +CNH R++ H QM +L
Sbjct: 705 FRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSE 764
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVK---PEILESMTADEK 349
+ E + ELK LA+ KG PP++ + P K PE+LE A
Sbjct: 765 KMRELQGVLDELKTDLARAKKG----------KPPLKDSDGKPKKNMTPEVLERKIAQTN 814
Query: 350 AQERKRAADLPKVPLLKSM 406
+ K D+ LK++
Sbjct: 815 TKIEKMERDMKTKEDLKTV 833
[10][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 68.2 bits (165), Expect = 3e-10
Identities = 46/139 (33%), Positives = 66/139 (47%), Gaps = 4/139 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + G +K+ Y NK VA +CNH R++ H QM +L
Sbjct: 611 FRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSE 670
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVK---PEILESMTADEK 349
+ E + ELK LA+ KG PP++ + P K PE+LE A
Sbjct: 671 KMRELQGVLDELKTDLARAKKG----------KPPLKDSDGKPKKNMTPEVLERKIAQTN 720
Query: 350 AQERKRAADLPKVPLLKSM 406
+ K D+ LK++
Sbjct: 721 TKIEKMERDMKTKEDLKTV 739
[11][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 67.8 bits (164), Expect = 4e-10
Identities = 46/126 (36%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + G V +KV Y NK VA +CNH RT+ H QM +L
Sbjct: 749 FRTYNASITLDDMLSKETKGGEVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNE 808
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ E ++ELK L++ K GK GA P + PE LE A A+
Sbjct: 809 KIDELKTAMEELKTDLSRVKK-GKPPSKGADGKPK------RNLNPEALERKMAQINAKI 861
Query: 359 RKRAAD 376
K D
Sbjct: 862 EKMERD 867
[12][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 67.4 bits (163), Expect = 5e-10
Identities = 45/126 (35%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + G V +KV Y + NK VA +CNH RT+ H QM +L
Sbjct: 748 FRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSAQMSRLNE 807
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ E ++ELK L++ K GK G P + PE LE A A+
Sbjct: 808 KIDELKTALEELKTDLSRAKK-GKPPSKGDDGEPK------RNLNPEALERKIAQTNAKI 860
Query: 359 RKRAAD 376
K D
Sbjct: 861 EKMERD 866
[13][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 66.6 bits (161), Expect = 8e-10
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 1/136 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRTFNAS+TL + L D + +K+ Y NK VA +CNH R++ H QM KL
Sbjct: 709 FRTFNASITLDDKLNKDTKDGDAAEKIVVYQHANKQVAIICNHQRSVSKSHSAQMTKLNE 768
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ E +KELK L + KG K+ S + PE+LE + A+
Sbjct: 769 KIDELQDVLKELKVDLDRARKGKSPTKSSDGKSK-------RSLTPEVLEKKISQTNAKI 821
Query: 359 RKRAADLPKVPLLKSM 406
K D+ LK++
Sbjct: 822 EKMQRDMKTKVDLKTV 837
[14][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 66.6 bits (161), Expect = 8e-10
Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 5/124 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + V +K+ YN+ NK VA +CNH RT+ H QM +L
Sbjct: 699 FRTYNASITLDEKLYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTE 758
Query: 179 RRAEAVAWVKELKRGLAKWNKGG---KGAKAGAASS-PPVEVTQYMPVKPEILESMTADE 346
+ E + +KELK L + KG KGA S P + + + + +E M
Sbjct: 759 KIEELKSTLKELKTDLDRAKKGKPPLKGADGKQKRSLTPEAIEKKIATTNQKIEKMEMAM 818
Query: 347 KAQE 358
K +E
Sbjct: 819 KTKE 822
[15][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 66.2 bits (160), Expect = 1e-09
Identities = 47/138 (34%), Positives = 69/138 (50%), Gaps = 7/138 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L + + T+ +K+A Y + NK VA +CNH R++ H+ QM KL
Sbjct: 743 FRTYNASITLDGILHEETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHESQMIKLNE 802
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTA------ 340
+ E + ++ELK L+K AK G E Q + PE +E A
Sbjct: 803 KIDELKSQMEELKADLSK-------AKKGKPLGYDKEGKQKRNLAPEAIEKKIAMVEGKI 855
Query: 341 DEKAQERKRAADLPKVPL 394
D+ ++K DL V L
Sbjct: 856 DKMEMDKKIKEDLKTVAL 873
[16][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 65.9 bits (159), Expect = 1e-09
Identities = 46/136 (33%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + V +KV Y + NK VA +CNH RT+ H QM KL
Sbjct: 713 FRTYNASITLDEKLYEETEDGDVAEKVVIYQRANKEVAIICNHQRTISKSHGAQMSKLIE 772
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ E A +KELK L + AK G + Q + PE +E A +
Sbjct: 773 KIEELKATLKELKTDLDR-------AKKGKPPLKDADGKQKRNLSPENIEKKIASTNQRI 825
Query: 359 RKRAADLPKVPLLKSM 406
K ++ LK++
Sbjct: 826 EKMELNMKTKEDLKTV 841
[17][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 64.7 bits (156), Expect = 3e-09
Identities = 41/126 (32%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + G V+ KVA Y NK VA +CNH R++ H QM +L+
Sbjct: 731 FRTYNASITLDEMLNKETKGGDVSQKVAVYQHANKEVAIICNHQRSVSKSHSTQMMRLDE 790
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
+ + +++ELK L++ KG K + + PE +E A +
Sbjct: 791 KINKLKNFIEELKTDLSRAKKGKPPLKGSDGKTK-------RNMNPEAIEKKIAQTNVKI 843
Query: 359 RKRAAD 376
K D
Sbjct: 844 EKMERD 849
[18][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 64.7 bits (156), Expect = 3e-09
Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 6/125 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + + T+ +K+A Y + NK VA +CNH R++ H QM +L
Sbjct: 738 FRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNE 797
Query: 179 RRAEAVAWVKELKRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 343
+ E A ELK L+K KG K K +P + ++ +I E M D
Sbjct: 798 KIDELKAQRDELKADLSKVRKGKNLGNDKDGKPKRNLAPEAFEKKISQIETKI-EKMEMD 856
Query: 344 EKAQE 358
+K +E
Sbjct: 857 KKIKE 861
[19][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 64.7 bits (156), Expect = 3e-09
Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 6/125 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L + + T+ +K+A Y + NK VA +CNH R++ H QM +L
Sbjct: 738 FRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNE 797
Query: 179 RRAEAVAWVKELKRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 343
+ E A ELK L+K KG K K +P + ++ +I E M D
Sbjct: 798 KIDELKAQRDELKADLSKVRKGKNLGNDKDGKPKRNLAPEAFEKKISQIETKI-EKMEMD 856
Query: 344 EKAQE 358
+K +E
Sbjct: 857 KKIKE 861
[20][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 63.9 bits (154), Expect = 5e-09
Identities = 37/91 (40%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L PGE + +K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 572 FRTYNASITLQQQLNELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQ 631
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 268
T+ + E K+ L+ K K AKA A
Sbjct: 632 TK-------IDEKKKQLSAAKKEHKAAKADA 655
[21][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 63.9 bits (154), Expect = 5e-09
Identities = 46/128 (35%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L D E V KV Y NK VA +CNH RT+ H QM +L
Sbjct: 680 FRTYNASITLDEMLNKDTKEGDVAQKVVVYQHANKEVAIICNHQRTISKSHTAQMTRLTE 739
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVT--QYMPVKPEILESMTADEKA 352
+ E + LK LA+ KG PP++ + + PE LE A A
Sbjct: 740 KIDEMKGVLNGLKTDLARAKKG----------KPPLKDADGKRRNLTPEALERKIAQTNA 789
Query: 353 QERKRAAD 376
+ K D
Sbjct: 790 KIEKMERD 797
[22][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 63.9 bits (154), Expect = 5e-09
Identities = 34/97 (35%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL E L + +T+++K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 84 FRTYNASSTLQEQLDLLTNEDDTLSEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLK 143
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPV 286
+ + +++E+++ + K AK G+ V
Sbjct: 144 EKIEQKREFIQEMQKXV---KDAAKDAKHGSVKEKVV 177
[23][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 63.9 bits (154), Expect = 5e-09
Identities = 47/140 (33%), Positives = 69/140 (49%), Gaps = 8/140 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRTFNAS+TL + LQ +P + V K+ YN+ N+ VA LCNH RT P + M L+
Sbjct: 326 FRTFNASLTLQDQLQKLTNPEDNVNAKILSYNRANRAVAILCNHQRTAPKTFEKSMSNLQ 385
Query: 176 TRRAEAVAWVKELKRGL------AKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMT 337
+ ++ VKE K+ L AK +K KA V+ + K E+ T
Sbjct: 386 LKISDKKKTVKEAKKELKALRVKAKESKSESNNKAVEKKKAQVQRLEEQLFKLEV----T 441
Query: 338 ADEKAQERKRAADLPKVPLL 397
A +K + ++ A K+ L
Sbjct: 442 ATDKEENKEIALGTSKLNYL 461
[24][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 63.9 bits (154), Expect = 5e-09
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 28/182 (15%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQK--- 169
FRT+NAS T+AE L+ P T+ DK+ FYN+ N+ VA LCNH R++ H QM++
Sbjct: 563 FRTYNASYTMAEELKKMPKNLTLADKILFYNRANRTVAILCNHQRSVTKNHDVQMERFAE 622
Query: 170 ----LETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVE--VTQYMPVKPEIL-- 325
L+ +R + L+ LAK + G S V+ T Y K +I
Sbjct: 623 RIKALQYQRMRLRKMMLNLEPKLAKSKPELLAKEEGITDSWIVKHHETLYELEKEKIKKK 682
Query: 326 -------------ESMTADEKAQERKRAADLPKVPL---LKSMRGDQLKSNLKRAEERLA 457
+S+ + + + R +AAD K L LKS + D +S++++ E+RL
Sbjct: 683 FDRENEKLAAEDPKSVLPESELEVRLKAADELKKALDAELKSKKVDPGRSSMEQLEKRLN 742
Query: 458 KL 463
KL
Sbjct: 743 KL 744
[25][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 63.9 bits (154), Expect = 5e-09
Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 11/156 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ------GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM 163
FRT+NAS+TL E ++ G V +KV Y NK VA +CNH RT+ H QM
Sbjct: 585 FRTYNASITLDEMVRCKLLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM 644
Query: 164 QKLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 343
+L + E +KEL+ L + NKG K + P K ++L+ +
Sbjct: 645 VRLNEKIEELKGLLKELQEDLTRVNKGKPPLK--NSDGKPKRNLNLKRYKGKLLKLIQKL 702
Query: 344 EKAQERKRAADLPKV-----PLLKSMRGDQLKSNLK 436
K E +R + K+ + K R + K +LK
Sbjct: 703 RKWSETRRLSVTKKIAQTNTKIEKMERDKETKEDLK 738
[26][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 63.5 bits (153), Expect = 7e-09
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGD-PGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + G V +K+ Y NK VA +CNH RT+ H QM +L
Sbjct: 716 FRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMTRLNG 775
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMP---VKPEILESMTADEK 349
+ E + L+ LA+ KG PP+E P + PE LE
Sbjct: 776 KIDELKGILDGLQTDLARAKKG----------KPPLEDADGKPKRNLTPEALERKIGQTN 825
Query: 350 AQERKRAAD 376
A+ K D
Sbjct: 826 AKIEKMERD 834
[27][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 63.2 bits (152), Expect = 9e-09
Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL E L + ++VT+K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 84 FRTYNASSTLQEQLDLLTNEDDSVTEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLK 143
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPV 286
+ + + E+++ + K AK G+ V
Sbjct: 144 EKIEQKKEHIAEMQKQV---KDAAKDAKHGSVKEKVV 177
[28][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 62.8 bits (151), Expect = 1e-08
Identities = 36/82 (43%), Positives = 51/82 (62%), Gaps = 9/82 (10%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS TL + L+ DP TV +K+ YN+ N+ VA LCNH R++P H+ M+
Sbjct: 844 FRTYNASWTLQQQLEELTDPNSTVAEKILSYNRANRAVAILCNHQRSVPKSHEKSMENLK 903
Query: 167 -KLETRR---AEAVAWVKELKR 220
K++ +R AEA VK+ KR
Sbjct: 904 AKIDAKREAIAEAEQIVKDAKR 925
[29][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 62.8 bits (151), Expect = 1e-08
Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL E L + + V +K YN+ NK VA +CNH RT+ H QM +L
Sbjct: 682 FRTYNASITLDEKLYEETEDGDVAEKFVIYNQANKQVAIICNHQRTISKSHDAQMSRLTE 741
Query: 179 RRAEAVAWVKELKRGLAKWNKG 244
+ E +KE K L + KG
Sbjct: 742 KLEELKGTLKEFKTDLDRAKKG 763
[30][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 62.8 bits (151), Expect = 1e-08
Identities = 33/82 (40%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L + + TV +K+A Y + NK VA +CNH R++ H+ QM ++
Sbjct: 396 FRTYNASITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNHQRSVSKSHESQMTRMNE 455
Query: 179 RRAEAVAWVKELKRGLAKWNKG 244
+ E + ++ELK L K KG
Sbjct: 456 KIDELKSQMEELKADLNKAKKG 477
[31][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 62.4 bits (150), Expect = 2e-08
Identities = 42/103 (40%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG-DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NASVTL + L G + +KVA YN NK VA +CNH R++ H Q+ KL
Sbjct: 699 FRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNE 758
Query: 179 RRAEAVAWVKELKRGLAKWNKGG---KGAKAGAASSPPVEVTQ 298
+ E A ++E K LA+ KG KGA A + E Q
Sbjct: 759 KIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQ 801
[32][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 62.4 bits (150), Expect = 2e-08
Identities = 31/75 (41%), Positives = 50/75 (66%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL E L + ++VT+K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 84 FRTYNASHTLQEQLDKLTNAEDSVTEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLK 143
Query: 176 TRRAEAVAWVKELKR 220
+ + ++E++R
Sbjct: 144 EKIDQKREQIEEMQR 158
[33][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 62.0 bits (149), Expect = 2e-08
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 6/92 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS TL E L+ +P +TV +K+ YN+ N+ VA LCNH R++P H+ M+
Sbjct: 792 FRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 851
Query: 167 -KLETRRAEAVAWVKELKRGLAKWNKGGKGAK 259
K+E +R + KE+K + G + K
Sbjct: 852 AKIEAKREQINEIKKEVKNAKRNGDSGTEAKK 883
[34][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 62.0 bits (149), Expect = 2e-08
Identities = 32/62 (51%), Positives = 42/62 (67%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T++ LQ P E T+ +KV YN N+ VA LCNH RT+ +GH+ QM+KL
Sbjct: 635 FRTYNASFTMSRLLQELPVEKATIAEKVKLYNDCNRKVAILCNHKRTVGAGHQAQMEKLG 694
Query: 176 TR 181
R
Sbjct: 695 DR 696
[35][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 61.6 bits (148), Expect = 3e-08
Identities = 36/82 (43%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH RT+ GH +QK T
Sbjct: 532 FRTYNASKTMQDQLDLIPNEGTVAEKILRYNAANRTVAILCNHQRTVTKGHASSVQK-AT 590
Query: 179 RRAEAVAWVK-ELKRGLAKWNK 241
R E + W K KR + + +K
Sbjct: 591 ERIEELEWQKVRYKRAILQLDK 612
[36][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 61.6 bits (148), Expect = 3e-08
Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 5/65 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 166
FRT+NAS T++E L+G DP +V +KV YN N+ VA LCNH RT+ +GH+ QMQ
Sbjct: 659 FRTYNASFTMSELLKGLSKDPRSRGSVAEKVKLYNDCNREVAILCNHKRTVGAGHEQQMQ 718
Query: 167 KLETR 181
KL R
Sbjct: 719 KLGDR 723
[37][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 61.6 bits (148), Expect = 3e-08
Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 3/162 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH RT+ GH +QK T
Sbjct: 503 FRTYNASKTMQDQLDLIPNEGTVAEKMLKYNAANRTVAILCNHQRTVTKGHAASVQK-AT 561
Query: 179 RRAEAVAWVK-ELKRGLAKWN-KGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
R E + W K LKR + + + K K A + Q + ++E ++
Sbjct: 562 ERIEELEWQKIRLKRAILQLDEKQAKKDPKFFAEVTDLVKEQEAAIHKRLIEK-EREKYV 620
Query: 353 QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSDME 478
++ R + K + + QLK + R +E + ++E
Sbjct: 621 KKFSRENEKRKFEKQEELPESQLKEWMARVDELEKQYNEELE 662
[38][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 61.2 bits (147), Expect = 3e-08
Identities = 46/142 (32%), Positives = 74/142 (52%), Gaps = 4/142 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP +V +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 868 FRTYNASKTLQNQLDLLTDPNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLK 927
Query: 176 TR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
+ RA+ A L ++++ K AK G+ + E + AD+K
Sbjct: 928 EKIRAKRDA----LDECESEYHDLRKAAKRGS-----------------VKEKLNADKKG 966
Query: 353 QERKRAAD-LPKVPLLKSMRGD 415
++ +R D L K+ L ++ R +
Sbjct: 967 KQLERLKDQLKKLELQETDRDE 988
[39][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 60.8 bits (146), Expect = 4e-08
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH M+KL+
Sbjct: 118 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKGHAKSMEKLK 177
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGK 250
+ + + E++R + + K
Sbjct: 178 EKIEQKKDTISEMERQVQDAQRAAK 202
[40][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 60.8 bits (146), Expect = 4e-08
Identities = 30/75 (40%), Positives = 48/75 (64%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 118 FRTYNASWTLQQQLDELTNDDDTVAEKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLK 177
Query: 176 TRRAEAVAWVKELKR 220
+ + + E++R
Sbjct: 178 EKIEQKREQINEMQR 192
[41][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 60.8 bits (146), Expect = 4e-08
Identities = 28/61 (45%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT NAS T++E L+ P + +++DKV YN+ N++VA LCNH RT+ H QM+++E
Sbjct: 511 FRTHNASYTMSEQLKNTPKDASISDKVLAYNRANRMVAILCNHQRTISKTHSAQMERIED 570
Query: 179 R 181
+
Sbjct: 571 K 571
[42][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 60.5 bits (145), Expect = 6e-08
Identities = 36/82 (43%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM---- 163
FRTFNAS TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+ M
Sbjct: 572 FRTFNASWTLQQQLEKLTDPDVSVAEKILQYNRANRAVAILCNHQRAIPKTHEKSMGNLK 631
Query: 164 QKLETRRA---EAVAWVKELKR 220
+K++T+RA EA K+ KR
Sbjct: 632 EKIQTKRAAVKEAKEQYKQAKR 653
[43][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 60.5 bits (145), Expect = 6e-08
Identities = 46/142 (32%), Positives = 74/142 (52%), Gaps = 4/142 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 879 FRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLK 938
Query: 176 TR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
+ RA+ A + ++++ K AK G+ + E + AD+K
Sbjct: 939 EKIRAKRDA----IDDCESEYHDLKKAAKRGS-----------------VKEKVNADKKG 977
Query: 353 QERKRAAD-LPKVPLLKSMRGD 415
++ +R D L K+ L ++ R +
Sbjct: 978 KQLERLKDQLKKLELQETDRDE 999
[44][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 60.5 bits (145), Expect = 6e-08
Identities = 46/142 (32%), Positives = 74/142 (52%), Gaps = 4/142 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 867 FRTYNASKTLQNQLDLLTDPSATVPEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLK 926
Query: 176 TR-RAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
+ RA+ A + ++++ K AK G+ + E + AD+K
Sbjct: 927 EKIRAKRDA----IDDCESEYHDLKKAAKRGS-----------------VKEKVNADKKG 965
Query: 353 QERKRAAD-LPKVPLLKSMRGD 415
++ +R D L K+ L ++ R +
Sbjct: 966 KQLERLKDQLKKLELQETDRDE 987
[45][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 60.5 bits (145), Expect = 6e-08
Identities = 54/166 (32%), Positives = 81/166 (48%), Gaps = 9/166 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L Q TV +KV YN N+ VA LCNH RT+ +GH QM+KL +
Sbjct: 635 FRTYNASYTMATLLKQMQATGTVHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKL-S 693
Query: 179 RRAEAVAW----VKELKRGLAKWNKGGKGAKAGAASSPP----VEVTQYMPVKPEILESM 334
R + +++ +K++ L K KG + S V+ Q V+ + +
Sbjct: 694 ERIKGLSYQKWRIKQMMIDLDPKIKKKKGPEFFQLDSDLDEEWVKQHQAFLVEEQRQKIQ 753
Query: 335 TADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSD 472
EK E+ RA K M+ +L+ L+ A+E AK +
Sbjct: 754 KKFEKENEKLRAEG------EKEMKAKELEQRLEAAKELEAKFKKE 793
[46][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 60.1 bits (144), Expect = 8e-08
Identities = 38/91 (41%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRTFNAS TL L+ DP TV +K+ YN+ N+ VA LCNH R +P H+ M L+
Sbjct: 795 FRTFNASFTLQNQLRELTDPDMTVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMSNLK 854
Query: 176 TR---RAEAVAWVKELKRGLAKWNKGGKGAK 259
+ + EAV + + L K N K AK
Sbjct: 855 EKIRAKQEAVETCERELKDLKKSNVRDKVAK 885
[47][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 60.1 bits (144), Expect = 8e-08
Identities = 29/75 (38%), Positives = 49/75 (65%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRTFNAS TL + L + +T+++K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 118 FRTFNASYTLQQQLDELTNADDTLSEKILSYNRANRAVAILCNHQRSVPKGHQKTMEKLK 177
Query: 176 TRRAEAVAWVKELKR 220
+ + + E+++
Sbjct: 178 EKIDQKREQITEMQK 192
[48][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 60.1 bits (144), Expect = 8e-08
Identities = 53/172 (30%), Positives = 81/172 (47%), Gaps = 15/172 (8%)
Frame = +2
Query: 2 FRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L Q + T+ +KV YN N+ VA LCNH RT+ +GH QM+KL
Sbjct: 651 FRTYNASYTMATLLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGE 710
Query: 179 R--RAEAVAW-VKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE------- 328
R W +K++ L K KGA ++ + P++ E
Sbjct: 711 RIKGLRYQKWRIKQMMLDLDPKIKKKKGA-------------EFFELDPDLDEEWIKQHQ 757
Query: 329 SMTADEKAQERKRAADLPKVPLL----KSMRGDQLKSNLKRAEERLAKLTSD 472
+ +E+ Q+ ++ D L K M+ +L+ L+ AEE AK +
Sbjct: 758 AFLVEEQRQKIQKKFDKDNEKLRAEGEKEMKVKELEKRLEVAEELAAKFKKE 809
[49][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 60.1 bits (144), Expect = 8e-08
Identities = 53/172 (30%), Positives = 81/172 (47%), Gaps = 15/172 (8%)
Frame = +2
Query: 2 FRTFNASVTLAECL-QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L Q + T+ +KV YN N+ VA LCNH RT+ +GH QM+KL
Sbjct: 651 FRTYNASYTMATLLRQMNATGTIHEKVKQYNDANRKVAILCNHKRTVAAGHANQMEKLGE 710
Query: 179 R--RAEAVAW-VKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE------- 328
R W +K++ L K KGA ++ + P++ E
Sbjct: 711 RIKGLRYQKWRIKQMMLDLDPKIKKKKGA-------------EFFELDPDLDEEWIKQHQ 757
Query: 329 SMTADEKAQERKRAADLPKVPLL----KSMRGDQLKSNLKRAEERLAKLTSD 472
+ +E+ Q+ ++ D L K M+ +L+ L+ AEE AK +
Sbjct: 758 AFLVEEQRQKIQKKFDKDNEKLRAEGEKEMKVKELEKRLEVAEELAAKFKKE 809
[50][TOP]
>UniRef100_UPI0001AE6F94 UPI0001AE6F94 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE6F94
Length = 477
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 220 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 279
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 280 TKIQAKKEQVAEARAELRRARAEHKAQGDG 309
[51][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 59.7 bits (143), Expect = 1e-07
Identities = 32/82 (39%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L + + TV +K+A Y + NK VA +CN R++ H+ QM ++
Sbjct: 726 FRTYNASITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNQQRSVSKSHESQMTRMNE 785
Query: 179 RRAEAVAWVKELKRGLAKWNKG 244
+ E + ++ELK L K KG
Sbjct: 786 KIDELKSQMEELKADLNKAKKG 807
[52][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 59.7 bits (143), Expect = 1e-07
Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L +TV +K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTSADDTVAEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLK 143
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGK 250
+ + V + +R L + K
Sbjct: 144 EKIEQKREQVADAQRQLKDAQRDAK 168
[53][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 59.7 bits (143), Expect = 1e-07
Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL + L+ P G TV +K+ Y + N+ VA LCNH R P H QM++L+
Sbjct: 2236 FRTYNASITLQDQLKSTPAGGTVEEKLLAYQRANRAVAILCNHQRAAPKTHDEQMERLD- 2294
Query: 179 RRAEAVAWV-KELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
EA+ + KEL + + K K +A + ++ + +K ++ ++ +
Sbjct: 2295 ---EALVKIQKELDSTIKERKKLKKDLRAQGSDVSKTDLNRLDVLKRKV-------DRLE 2344
Query: 356 ERKRAADLPKV 388
ER + KV
Sbjct: 2345 ERLHKKQIAKV 2355
[54][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 327 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 386
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 387 TKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[55][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 327 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 386
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 387 TKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[56][TOP]
>UniRef100_B4E061 cDNA FLJ51170, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E061_HUMAN
Length = 477
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 220 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 279
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 280 TKIQAKKEQVAEARAELRRARAEHKAQGDG 309
[57][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 327 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 386
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 387 TKIQAKKEQVAEARAELRRARAEHKAQGDG 416
[58][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 59.7 bits (143), Expect = 1e-07
Identities = 41/90 (45%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T A L+ E TV +KV YN N+ VA LCNH RT+ +GH QM+KL
Sbjct: 610 FRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGD 669
Query: 179 R--RAEAVAW-VKELKRGLAKWNKGGKGAK 259
R W VK + L K KGAK
Sbjct: 670 RIKGLRYQKWRVKMMMLDLDPSQKKKKGAK 699
[59][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 425 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 484
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 485 TKIQAKKEQVAEARAELRRARAEHKAQGDG 514
[60][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 59.7 bits (143), Expect = 1e-07
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +++ K+ YN+ N+VVA LCNH R PS + MQ L+
Sbjct: 425 FRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQ 484
Query: 176 TR---RAEAVAWVK-ELKRGLAKWNKGGKG 253
T+ + E VA + EL+R A+ G G
Sbjct: 485 TKIQAKKEQVAEARAELRRARAEHKAQGDG 514
[61][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 59.3 bits (142), Expect = 1e-07
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + ++V +K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 761 FRTYNASWTLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLK 820
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPV 286
+ +K+ +R + K AK G+ V
Sbjct: 821 EKIDAKKEAIKDAERQV---KDAAKDAKHGSVKEKTV 854
[62][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 59.3 bits (142), Expect = 1e-07
Identities = 43/132 (32%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L + + V +KV Y + NK VA +CNH RT+ H Q++KL
Sbjct: 733 FRTYNASITLDLMLSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAV 792
Query: 179 RRAEAVAWVKELKRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 343
+ E +KEL L + KG G K +P + M + +I E M D
Sbjct: 793 KIEELREQIKELNIDLDRAKKGRTPLMGSDGKRKRNLTPEALEKKIMQTQGKI-EKMERD 851
Query: 344 EKAQERKRAADL 379
+ +E + L
Sbjct: 852 MQTKEDMKTVAL 863
[63][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 59.3 bits (142), Expect = 1e-07
Identities = 43/132 (32%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L + + V +KV Y + NK VA +CNH RT+ H Q++KL
Sbjct: 48 FRTYNASITLDLMLSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAV 107
Query: 179 RRAEAVAWVKELKRGLAKWNKG-----GKGAKAGAASSPPVEVTQYMPVKPEILESMTAD 343
+ E +KEL L + KG G K +P + M + +I E M D
Sbjct: 108 KIEELREQIKELNIDLDRAKKGRTPLMGSDGKRKRNLTPEALEKKIMQTQGKI-EKMERD 166
Query: 344 EKAQERKRAADL 379
+ +E + L
Sbjct: 167 MQTKEDMKTVAL 178
[64][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 59.3 bits (142), Expect = 1e-07
Identities = 29/62 (46%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 829 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKGHQKSMENLK 888
Query: 176 TR 181
+
Sbjct: 889 EK 890
[65][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 59.3 bits (142), Expect = 1e-07
Identities = 31/78 (39%), Positives = 50/78 (64%), Gaps = 6/78 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + ++V++K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 66 FRTYNASFTLQQQLDQLTNADDSVSEKMLSYNRANRAVAVLCNHQRSVPKGHEKSMEKLK 125
Query: 176 ----TRRAEAVAWVKELK 217
T+R + K++K
Sbjct: 126 EKIGTKRDQIAEMEKQVK 143
[66][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 58.9 bits (141), Expect = 2e-07
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 3/141 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L D TV +K+ YN+ N+ VA LCNH R++P GH+ M L+
Sbjct: 888 FRTYNASKTLQSQLDLLTDGSATVAEKLLAYNRANRAVAILCNHQRSVPKGHQKSMDNLK 947
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
+ + + + A+++ K AK G+ + E + AD+KA+
Sbjct: 948 EKIRAKRDNIDDCE---AEYHDLKKAAKRGS-----------------VKEKVNADKKAK 987
Query: 356 ERKRAAD-LPKVPLLKSMRGD 415
+ +R D L K+ L ++ R +
Sbjct: 988 QLERLKDQLKKLELQETDRDE 1008
[67][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 58.9 bits (141), Expect = 2e-07
Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +T+ +K+ YN+ N+ VA LCNH R++P GH+ M+KL+
Sbjct: 118 FRTYNASWTLQQQLDELTNADDTLAEKILSYNRANRAVAILCNHQRSVPKGHQKSMEKLK 177
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGK 250
+ + + +++R + K K
Sbjct: 178 EKIDQKKENITDMQRQVKDAQKDAK 202
[68][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 58.9 bits (141), Expect = 2e-07
Identities = 32/61 (52%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T A L+ E TV +KV YN N+ VA LCNH RT+ +GH QM+KL
Sbjct: 606 FRTYNASYTFATLLKDMKAEGTVAEKVKQYNDANRRVAILCNHKRTVTAGHANQMEKLGD 665
Query: 179 R 181
R
Sbjct: 666 R 666
[69][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 58.9 bits (141), Expect = 2e-07
Identities = 36/88 (40%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G MQKLE
Sbjct: 566 FRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLE 625
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAK 259
+ + VKE + L K +GA+
Sbjct: 626 QKIKDKKKEVKEAEAAL----KSARGAE 649
[70][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 58.9 bits (141), Expect = 2e-07
Identities = 36/88 (40%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECL--QGDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L +P + V K+ YN+ N+ VA LCNH R + G MQKLE
Sbjct: 638 FRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLE 697
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAK 259
+ + VKE + L K +GA+
Sbjct: 698 QKIKDKKKEVKEAEAAL----KSARGAE 721
[71][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 58.5 bits (140), Expect = 2e-07
Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ E L P E +V +K+ YN N+ VA LCNH RT+ +GH + K +
Sbjct: 464 FRTYNASKTMQEQLDLIPNEGSVAEKLLKYNAANRTVAILCNHQRTVTAGHAKSVAK-SS 522
Query: 179 RRAEAVAWVKE-LKRGL 226
R E W KE LK+G+
Sbjct: 523 DRIEEFKWQKERLKKGI 539
[72][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 58.2 bits (139), Expect = 3e-07
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM---- 163
FRTFNAS TL + L+ DP +V +K+ YN+ N+ VA LCNH R +P H+ M
Sbjct: 813 FRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLK 872
Query: 164 QKLETRRAEAVAWVKELKR 220
+K+ +R + KE K+
Sbjct: 873 EKIRVKREQVEQCQKEFKK 891
[73][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 58.2 bits (139), Expect = 3e-07
Identities = 36/83 (43%), Positives = 47/83 (56%), Gaps = 9/83 (10%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRTFNAS TL L DP TV +K+ YN+ N+ VA LCNH R +P H M L+
Sbjct: 790 FRTFNASFTLQNQLAELTDPNMTVPEKMLAYNRANRAVAILCNHQRAVPKTHDKSMSNLK 849
Query: 176 TR---RAEAVAW----VKELKRG 223
+ + EAV +K++KRG
Sbjct: 850 EKIRLKKEAVETCQRELKDMKRG 872
[74][TOP]
>UniRef100_UPI000192545C PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Hydra
magnipapillata RepID=UPI000192545C
Length = 726
Score = 57.8 bits (138), Expect = 4e-07
Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS+TL + L + G +VT K YN+ N+ VA LCNH R P QM+
Sbjct: 538 FRTYNASITLQQQLNELTEEGASVTAKFLQYNRANRAVAILCNHQRAAPKTFDKQMENIV 597
Query: 167 -KLETRRAEAVAWVKELKRGLAKWNKGGKGAK 259
KL+ ++ + A KE+K ++++ GK K
Sbjct: 598 NKLKEKKKQMKAVKKEIKELKREYHEKGKSEK 629
[75][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 57.8 bits (138), Expect = 4e-07
Identities = 46/143 (32%), Positives = 66/143 (46%), Gaps = 2/143 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +K+ YN N+ VA LCNH R++ GH ++K+
Sbjct: 491 FRTYNASKTMQDQLDLIPNEGTVAEKLLKYNAANRAVAILCNHQRSVTKGHAQSVEKM-N 549
Query: 179 RRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
++ E + W K LK+G+ + P + EI MT E+A
Sbjct: 550 QKIEELLWQKIRLKKGILQLE--------------PSRAQKNKKYFKEI-NDMTKVEQAT 594
Query: 356 ERKRAADLPKVPLLKSMRGDQLK 424
KR D + L K D K
Sbjct: 595 IHKRIVDRERERLKKKFERDNEK 617
[76][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 57.8 bits (138), Expect = 4e-07
Identities = 30/62 (48%), Positives = 42/62 (67%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T+++ LQ E T+ +K+ YN N+ VA LCNH RT+ +GH+ QM+KL
Sbjct: 650 FRTYNASWTMSQLLQKLEVEDRTMAEKIKLYNDCNREVAILCNHKRTVGAGHEAQMEKLG 709
Query: 176 TR 181
R
Sbjct: 710 DR 711
[77][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 57.4 bits (137), Expect = 5e-07
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 7/139 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS+TL E L+ D + V K+ YN+ N+ VA LCNH R P + MQ
Sbjct: 513 FRTYNASITLQEQLKALTDAEDNVAAKILSYNRANRAVAILCNHQRATPKTFEKSMQNLQ 572
Query: 167 -KLETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE-SMTA 340
K++ ++ + V ELKR A +K K K+ + ++ Q ++ ++++ S+ A
Sbjct: 573 AKIDAKKEQLDEAVTELKRAKAD-HKAKKDIKSKSNLEKKKKLLQ--KIEEQLMKLSVQA 629
Query: 341 DEKAQERKRAADLPKVPLL 397
+K + ++ A K+ L
Sbjct: 630 TDKEENKQIALGTSKLNYL 648
[78][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 57.4 bits (137), Expect = 5e-07
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 5/162 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+G T+ +K+ YN N+ VA LCNH RT+ + H QM+KL
Sbjct: 651 FRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGD 710
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQE 358
R LK+ + + K K GAA E +K ++ +E+ Q+
Sbjct: 711 RIKGLKYQQWRLKQMMLDLDPKLK-KKKGAAYFELDESLDQEWIKEH--QAFLVEEQRQK 767
Query: 359 RKRAADLPKVPLL----KSMRGDQLKSNLKRAEERLAKLTSD 472
K+ + + K M+ +L+ L+ A E AK +
Sbjct: 768 IKKKFEKDNEKRVAEGEKEMKAKELEERLEAANELEAKFKKE 809
[79][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 57.4 bits (137), Expect = 5e-07
Identities = 32/74 (43%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ GH +QK+
Sbjct: 526 FRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKGHGSSVQKIND 585
Query: 179 RRAEAVAWVKELKR 220
+ E + LKR
Sbjct: 586 KLKELMWQKIRLKR 599
[80][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 41/62 (66%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P + MQ L+
Sbjct: 417 FRTYNASITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQ 476
Query: 176 TR 181
T+
Sbjct: 477 TK 478
[81][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 41/62 (66%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL E L+ +P ++V K+ YN+ N+ VA LCNH R+ P + MQ L+
Sbjct: 417 FRTYNASITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQ 476
Query: 176 TR 181
T+
Sbjct: 477 TK 478
[82][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 57.0 bits (136), Expect = 6e-07
Identities = 46/132 (34%), Positives = 65/132 (49%), Gaps = 7/132 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQK 169
FRT+NAS+TL + L P T +KV FYN+ N+ VA LCNH R+L H M K
Sbjct: 783 FRTYNASLTLEKELAKMPESLIKATADEKVLFYNRCNREVAILCNHQRSLSKTHTETMGK 842
Query: 170 LETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEIL---ESMTA 340
++ + AE + KE + + K GKG K + S E T + E+ ++
Sbjct: 843 IDEKIAE---FKKEKLQQQIAYLK-GKGKKPVLSDSESDEDTPKKATPKKATPKKETKSS 898
Query: 341 DEKAQERKRAAD 376
DE +KR D
Sbjct: 899 DEATPNKKRKKD 910
[83][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 420 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 479
Query: 176 TR 181
+
Sbjct: 480 EK 481
[84][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 813 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 872
Query: 176 TR 181
+
Sbjct: 873 EK 874
[85][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 420 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 479
Query: 176 TR 181
+
Sbjct: 480 EK 481
[86][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 419 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 478
Query: 176 TR 181
+
Sbjct: 479 EK 480
[87][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 809 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 868
Query: 176 TR 181
+
Sbjct: 869 EK 870
[88][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 57.0 bits (136), Expect = 6e-07
Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL E L DP ++ DK+ YN+ N+ VA LCNH RT+ QM L
Sbjct: 384 FRTYNASYTLQEQLHQVIDPKMSIEDKILIYNRSNRAVAILCNHQRTVSKTFDKQMSNLR 443
Query: 176 TRRAEAVAWVKELKR 220
+ + +KE K+
Sbjct: 444 EKIEKKEQQLKEAKK 458
[89][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 808 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 867
Query: 176 TR 181
+
Sbjct: 868 EK 869
[90][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 57.0 bits (136), Expect = 6e-07
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 6/78 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL- 172
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 173 ---ETRRAEAVAWVKELK 217
E +R + V K++K
Sbjct: 144 EKIEQKREQIVDAQKQVK 161
[91][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 57.0 bits (136), Expect = 6e-07
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 6/78 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL- 172
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 173 ---ETRRAEAVAWVKELK 217
E +R + V K++K
Sbjct: 144 EKIEQKREQIVDAQKQVK 161
[92][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 57.0 bits (136), Expect = 6e-07
Identities = 29/61 (47%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+G T+ +K+ YN N+ VA LCNH RT+ + H QM+KL
Sbjct: 646 FRTYNASYTMATLLKGMKSTGTIAEKIKDYNDANRQVAILCNHKRTVTASHSTQMEKLGD 705
Query: 179 R 181
R
Sbjct: 706 R 706
[93][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster
RepID=TOP1_DROME
Length = 972
Score = 57.0 bits (136), Expect = 6e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L DP TV +K+ YN+ N+ VA LCNH R++P H+ M+ L+
Sbjct: 811 FRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLK 870
Query: 176 TR 181
+
Sbjct: 871 EK 872
[94][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 56.6 bits (135), Expect = 8e-07
Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 6/79 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ
Sbjct: 120 FRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQ 179
Query: 167 -KLETRRAEAVAWVKELKR 220
K+ET++A+ EL++
Sbjct: 180 KKIETKKAQVAEAQVELQK 198
[95][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 56.6 bits (135), Expect = 8e-07
Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 6/79 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ
Sbjct: 417 FRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQ 476
Query: 167 -KLETRRAEAVAWVKELKR 220
K+ET++A+ EL++
Sbjct: 477 KKIETKKAQVAEAQVELQK 495
[96][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 56.6 bits (135), Expect = 8e-07
Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L D TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 822 FRTYNASKTLQDQLDKLTDGDATVAEKLLAYNRANRAVAILCNHQRSVPKGHQKSMENLK 881
Query: 176 TR 181
+
Sbjct: 882 EK 883
[97][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 56.6 bits (135), Expect = 8e-07
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 8/161 (4%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+ T+ +KV YN N+ VA LCNH RT+ + H QM+KL
Sbjct: 642 FRTYNASYTMATLLKKMSATGTIPEKVKQYNDANREVAILCNHKRTVAASHANQMEKLGD 701
Query: 179 R--RAEAVAW-VKELKRGLAKWNKGGKGAKAGAASSPP----VEVTQYMPVKPEILESMT 337
R + W +K++ + K KGA ++ Q V+ E+ + +
Sbjct: 702 RIKGLQYQKWRIKQMMLDIDSKIKKKKGAAYFELDDDLDMEWIKEHQAFLVE-ELRQKIR 760
Query: 338 ADEKAQERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAK 460
+ KR AD K M+ +L+ LK A+E AK
Sbjct: 761 KKFDKENEKRVADGE-----KEMKAKELEERLKAADELEAK 796
[98][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 56.6 bits (135), Expect = 8e-07
Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 6/79 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NASVTL E L+ ++VT KV YN+ N+ VA LCNH R +P + MQ
Sbjct: 418 FRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQ 477
Query: 167 -KLETRRAEAVAWVKELKR 220
K+ET++A+ EL++
Sbjct: 478 KKIETKKAQVAEAQVELQK 496
[99][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 56.2 bits (134), Expect = 1e-06
Identities = 30/77 (38%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL E L+ + ++ +K+ YN+ N+ VA LCNH R +P QM+ L+
Sbjct: 106 FRTYNASKTLQEQLELLTEADMSLPEKMLAYNRANRAVAILCNHQRAVPKTFDKQMENLQ 165
Query: 176 TRRAEAVAWVKELKRGL 226
+ E A ++E K+ L
Sbjct: 166 KKMEEKEAQIRECKKEL 182
[100][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 56.2 bits (134), Expect = 1e-06
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL L D TV +K+ YN+ N+ VA LCNH R++P GH+ M+ L
Sbjct: 451 FRTYNASLTLQNQLDELTDEEATVAEKLLVYNRANRAVAILCNHQRSIPKGHQQIMENLR 510
Query: 176 TR 181
+
Sbjct: 511 KK 512
[101][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 56.2 bits (134), Expect = 1e-06
Identities = 28/75 (37%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TRRAEAVAWVKELKR 220
+ + ++E ++
Sbjct: 144 EKIEQKREQIEEAQK 158
[102][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 56.2 bits (134), Expect = 1e-06
Identities = 27/75 (36%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +++++K+ YN+ N+ VA LCNH R +P GH+ M+K++
Sbjct: 84 FRTYNASWTLQQQLDKLTNEDDSISEKILSYNRANRAVAILCNHQRAVPKGHEKSMEKIK 143
Query: 176 TRRAEAVAWVKELKR 220
+ +K+ +R
Sbjct: 144 EKIDAKRQAIKDAER 158
[103][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 56.2 bits (134), Expect = 1e-06
Identities = 32/70 (45%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E +VT+K+ YN N+ VA LCNH RT+ H MQK T
Sbjct: 479 FRTYNASKTMQDQLDLIPNEGSVTEKMVRYNAANRAVAILCNHQRTVGRSHAQSMQK-AT 537
Query: 179 RRAEAVAWVK 208
+ E W K
Sbjct: 538 EKIEEYQWQK 547
[104][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 55.8 bits (133), Expect = 1e-06
Identities = 32/77 (41%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L D ++VT K+ YN+ N+ VA LCNH R P QM+ L+
Sbjct: 264 FRTYNASSTLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQ 323
Query: 176 TRRAEAVAWVKELKRGL 226
+ + +KE K+GL
Sbjct: 324 EKIDKKHLDIKEAKKGL 340
[105][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E471B7
Length = 879
Score = 55.8 bits (133), Expect = 1e-06
Identities = 32/77 (41%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L D ++VT K+ YN+ N+ VA LCNH R P QM+ L+
Sbjct: 703 FRTYNASSTLQNQLVELTDADDSVTAKMLSYNRANRAVAVLCNHQRAAPKTFDKQMENLQ 762
Query: 176 TRRAEAVAWVKELKRGL 226
+ + +KE K+GL
Sbjct: 763 EKIDKKHLDIKEAKKGL 779
[106][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP-GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS+TL L+ +T K A Y+ NK VA LCNH + + H QM+KL
Sbjct: 322 FRTYNASITLDRLLKDTKKNDTTLQKKATYDAANKEVAILCNHQKGVSKAHDAQMEKLAE 381
Query: 179 RRAEAVAWVKELKR 220
++ + V E+K+
Sbjct: 382 KKKDLAKQVAEMKK 395
[107][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[108][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[109][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[110][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[111][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[112][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[113][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +T +K+ YN+ N+ VA LCNH R++P GH M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNEDDTEAEKILSYNRANRAVAILCNHQRSVPKGHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[114][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 55.5 bits (132), Expect = 2e-06
Identities = 55/168 (32%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T+++ LQ TV +KV YN N+ VA LCNH RT+ + H+ QM+KL
Sbjct: 617 FRTYNASYTMSKLLQELKVTNATVHEKVKLYNDCNRQVAILCNHKRTVGASHEQQMKKL- 675
Query: 176 TRRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
+ + + + K K + + K K A ++T+ + E + D+KA
Sbjct: 676 VEQIKGLRYQKWRTKMMMLDLDPKLKKKKGAAYFELDEDLTEEWVKSHQ--EFLVEDQKA 733
Query: 353 Q--------ERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAKLTSD 472
+ KR AD K PL S +LK LK A E AK +
Sbjct: 734 KINKKFEKDNEKRIADGEK-PLPAS----ELKERLKAASELEAKFKKE 776
[115][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 55.5 bits (132), Expect = 2e-06
Identities = 32/79 (40%), Positives = 48/79 (60%), Gaps = 6/79 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS+TL E L+ +++T KV YN+ N+ VA LCNH R +P + MQ
Sbjct: 418 FRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQ 477
Query: 167 -KLETRRAEAVAWVKELKR 220
K+ET++A+ EL++
Sbjct: 478 KKIETKKAQVAEAQVELQK 496
[116][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 55.1 bits (131), Expect = 2e-06
Identities = 33/93 (35%), Positives = 54/93 (58%), Gaps = 6/93 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ--- 166
FRT+NAS+TL E L+ +P + + K+ YN+ N+ VA LCNH R++P MQ
Sbjct: 486 FRTYNASITLQEQLKALTNPEDNIAGKLLSYNRANRAVAILCNHQRSIPKTFAKSMQVLQ 545
Query: 167 -KLETRRAEAVAWVKELKRGLAKWNKGGKGAKA 262
K++ ++ + +E+K+ ++ K K AKA
Sbjct: 546 EKIDAKKKQVEEAQEEVKKAEDEF-KDTKDAKA 577
[117][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 55.1 bits (131), Expect = 2e-06
Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPG-ETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM--- 163
FRT+NAS+TL L DP E V K+ YN+ N+ VA LCNH R P QM
Sbjct: 305 FRTYNASITLLNQLLELTDPDDENVASKILSYNRANRAVAVLCNHQRAAPKNFSEQMGRM 364
Query: 164 -QKLETRRAEAVAWVKELKRGLA--KWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 334
+K+E ++ + +E K + K NK KA VE Q +K E+
Sbjct: 365 NEKIEKKQRDIQDAKQETKSAKSDYKHNKSEAKRKAYEGKKKKVERLQEQLIKLEV---- 420
Query: 335 TADEKAQERKRAADLPKVPLL 397
A +K + ++ A K+ L
Sbjct: 421 QATDKEENKEIALGTSKLNYL 441
[118][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 55.1 bits (131), Expect = 2e-06
Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 740 FRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 799
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESM 334
T+ + K LA + K AKA A V+ + + K + ++ +
Sbjct: 800 TK-------IDAKKDQLADARRDLKSAKAEAKVRKDVKTKKVVETKKKAVQRL 845
[119][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 55.1 bits (131), Expect = 2e-06
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM---- 163
FRT+NAS+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P M
Sbjct: 327 FRTYNASITLQQQLQELTDPEESMPSKILSYNRANRAVAILCNHQRAPPKTFDQSMANLK 386
Query: 164 QKLETRRAEAVAWVKELK 217
K++ ++ + + KELK
Sbjct: 387 SKIDAKKEQILLAKKELK 404
[120][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 55.1 bits (131), Expect = 2e-06
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQM---- 163
FRT+NAS+TL + LQ DP E++ K+ YN+ N+ VA LCNH R P M
Sbjct: 327 FRTYNASITLQQQLQELTDPEESIPAKILSYNRANRAVAILCNHQRAPPKTFDQSMANLK 386
Query: 164 QKLETRRAEAVAWVKELK 217
K++ ++ + + KELK
Sbjct: 387 SKIDAKKEQILLAKKELK 404
[121][TOP]
>UniRef100_Q581U8 DNA topoisomerase IB, large subunit n=1 Tax=Trypanosoma brucei
RepID=Q581U8_9TRYP
Length = 661
Score = 55.1 bits (131), Expect = 2e-06
Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL E + DP +++DK+ ++NK N VA+LCNH R++P +Q +
Sbjct: 435 FRTYNASITLDEWFREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHVSVQSI 494
Query: 173 ETRRAEAVAWVKELKR 220
+ + + + L+R
Sbjct: 495 KYKLEDIKRTIDTLRR 510
[122][TOP]
>UniRef100_C9ZLY6 DNA topoisomerase IB, large subunit, putative n=2 Tax=Trypanosoma
brucei RepID=C9ZLY6_TRYBG
Length = 696
Score = 55.1 bits (131), Expect = 2e-06
Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL E + DP +++DK+ ++NK N VA+LCNH R++P +Q +
Sbjct: 470 FRTYNASITLDEWFREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHVSVQSI 529
Query: 173 ETRRAEAVAWVKELKR 220
+ + + + L+R
Sbjct: 530 KYKLEDIKRTIDTLRR 545
[123][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 55.1 bits (131), Expect = 2e-06
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL L D +V +K+ YN+ N+ VA LCNH R++P GH+ M+ L+
Sbjct: 870 FRTYNASKTLQNQLDLLTDSNASVAEKLLTYNRANRAVAILCNHQRSVPKGHQKSMENLK 929
Query: 176 TR 181
+
Sbjct: 930 EK 931
[124][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 55.1 bits (131), Expect = 2e-06
Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +TV +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNAEDTVAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[125][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 55.1 bits (131), Expect = 2e-06
Identities = 26/62 (41%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +T+ +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDTIAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TR 181
+
Sbjct: 144 EK 145
[126][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina
RepID=B2AY06_PODAN
Length = 904
Score = 55.1 bits (131), Expect = 2e-06
Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T++ LQ E T+ +K+ YN N+ VA +CNH RT+ + H+ QM+KL
Sbjct: 647 FRTYNASHTMSTLLQSLSVENRTMAEKIKLYNDCNREVAVICNHKRTVGAAHEAQMEKLA 706
Query: 176 TR 181
R
Sbjct: 707 DR 708
[127][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 54.7 bits (130), Expect = 3e-06
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 8/115 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 579 FRTYNASITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 638
Query: 176 T----RRAEAVAWVKELK--RGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEI 322
T ++A+ A +ELK + AK + K KA A V+ +K E+
Sbjct: 639 TKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKKAVEAKKKAVQRIDDQLMKLEV 693
[128][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 54.7 bits (130), Expect = 3e-06
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 8/115 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 577 FRTYNASITLQAQLKELTSAEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 636
Query: 176 T----RRAEAVAWVKELK--RGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEI 322
T ++A+ A +ELK + AK + K KA A V+ +K E+
Sbjct: 637 TKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKKAVEAKKKAVQRIDDQLMKLEV 691
[129][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 54.7 bits (130), Expect = 3e-06
Identities = 36/91 (39%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L + + V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 582 FRTYNASITLQQQLNELTNSEDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 641
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 268
T+ + E KR L KGAKA A
Sbjct: 642 TKIDAKKEQLVEAKREL-------KGAKADA 665
[130][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 54.7 bits (130), Expect = 3e-06
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 12/131 (9%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--------DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKG 157
FRT+NAS+ L L +TV K Y+ NK VA LCNH R++P H
Sbjct: 401 FRTYNASIVLDRLLSEWEATKKGHSTAQTVDQKKVDYDIANKEVAILCNHQRSVPKTHTN 460
Query: 158 QMQKLETRRAEAVAWVKELKRGLAKWNKG----GKGAKAGAASSPPVEVTQYMPVKPEIL 325
QM+K++ + A + EL+ L KG K K GA + P + + K + +
Sbjct: 461 QMEKIQEKLAGMNKELAELEDELRAAQKGKAENKKANKCGAPTILPWALNSKIDKKKQAI 520
Query: 326 ESMTADEKAQE 358
+ +++E
Sbjct: 521 AKVELQARSKE 531
[131][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 54.7 bits (130), Expect = 3e-06
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH ++K
Sbjct: 492 FRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANN 551
Query: 179 RRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
R E + W K KR + + +K ++ + P E ++ +T +++A
Sbjct: 552 RIQE-LEWQKIRCKRAILQLDK---------------DLLKKEPKYFEEIDDLTKEDEAT 595
Query: 356 ERKRAAD 376
KR D
Sbjct: 596 IHKRIID 602
[132][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 54.7 bits (130), Expect = 3e-06
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH ++K
Sbjct: 516 FRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANN 575
Query: 179 RRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
R E + W K KR + + +K ++ + P E ++ +T +++A
Sbjct: 576 RIQE-LEWQKIRCKRAILQLDK---------------DLLKKEPKYFEEIDDLTKEDEAT 619
Query: 356 ERKRAAD 376
KR D
Sbjct: 620 IHKRIID 626
[133][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 54.7 bits (130), Expect = 3e-06
Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP--GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T L + T+ +K+ YNK N++VA LCNH R P H M+K+
Sbjct: 627 FRTYNASSTFQRLLDEEDLTNATIQEKINAYNKANRMVAILCNHQRAAPKTHDQSMEKMR 686
Query: 176 TRRAEAVAWVKELK 217
+ A V K K
Sbjct: 687 YKAAPVVEMKKNKK 700
[134][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 54.7 bits (130), Expect = 3e-06
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P + +V +K+ YN N+ VA LCNH RT+ GH ++K
Sbjct: 516 FRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANN 575
Query: 179 RRAEAVAWVK-ELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKAQ 355
R E + W K KR + + +K ++ + P E ++ +T +++A
Sbjct: 576 RIQE-LEWQKIRCKRAILQLDK---------------DLLKKEPKYFEEIDDLTKEDEAT 619
Query: 356 ERKRAAD 376
KR D
Sbjct: 620 IHKRIID 626
[135][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 54.3 bits (129), Expect = 4e-06
Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 7/128 (5%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NASVTL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 605 FRTYNASVTLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 664
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGA-----ASSPPVEVTQYMPVKPEILESMTA 340
T+ + K LA + K AKA A A S V T+ V+ + M
Sbjct: 665 TK-------IDAKKDQLANARRDLKSAKADAKVQRDAKSKKVVETKKKAVQRLEEQLMKL 717
Query: 341 DEKAQERK 364
+ +A +R+
Sbjct: 718 EVQATDRE 725
[136][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 54.3 bits (129), Expect = 4e-06
Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ +++ K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 594 FRTYNASITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 653
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K KGAKA +S + + + VK + ++
Sbjct: 654 TK-------IDEKQKQLSAARKQLKGAKAEHKASHDDKSKKAVEVKRKAVQ 697
[137][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 54.3 bits (129), Expect = 4e-06
Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ +++ K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 607 FRTYNASITLQQQLKELSCSDDSLPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 666
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K KGAKA +S + + + VK + ++
Sbjct: 667 TK-------IDEKQKQLSAARKQLKGAKAEHKASHDDKSKKAVEVKRKAVQ 710
[138][TOP]
>UniRef100_Q9Y180 Topoisomerase I-like protein n=1 Tax=Leishmania infantum
RepID=Q9Y180_LEIIN
Length = 635
Score = 54.3 bits (129), Expect = 4e-06
Identities = 46/156 (29%), Positives = 73/156 (46%), Gaps = 3/156 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K QM +L
Sbjct: 409 FRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQL 468
Query: 173 ETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
T+ + ++ L K K A+ +E M + E LES +E+
Sbjct: 469 TTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESYGTEEQK 522
Query: 353 QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAK 460
+E + P ++S + + S K+AE K
Sbjct: 523 KEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 557
[139][TOP]
>UniRef100_Q9NJG8 DNA topoisomerase I n=1 Tax=Leishmania donovani donovani
RepID=Q9NJG8_LEIDO
Length = 949
Score = 54.3 bits (129), Expect = 4e-06
Identities = 46/156 (29%), Positives = 73/156 (46%), Gaps = 3/156 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K QM +L
Sbjct: 723 FRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQL 782
Query: 173 ETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
T+ + ++ L K K A+ +E M + E LES +E+
Sbjct: 783 TTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESYGTEEQK 836
Query: 353 QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAK 460
+E + P ++S + + S K+AE K
Sbjct: 837 KEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 871
[140][TOP]
>UniRef100_Q9GPZ9 DNA topoisomerase I n=1 Tax=Leishmania infantum RepID=Q9GPZ9_LEIIN
Length = 635
Score = 54.3 bits (129), Expect = 4e-06
Identities = 46/156 (29%), Positives = 73/156 (46%), Gaps = 3/156 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K QM +L
Sbjct: 409 FRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQL 468
Query: 173 ETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
T+ + ++ L K K A+ +E M + E LES +E+
Sbjct: 469 TTKS----EYTRKTIELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESYGTEEQK 522
Query: 353 QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAK 460
+E + P ++S + + S K+AE K
Sbjct: 523 KEFEEIVAKRAAPRVRSEK-KKSTSGAKKAESASGK 557
[141][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 54.3 bits (129), Expect = 4e-06
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+AE L+ + +KV YN N+ VA LCNH RT+ + H QM+K+
Sbjct: 618 FRTYNASHTMAELLKDMKATGNIAEKVKAYNDANRRVAILCNHKRTVGASHANQMEKMSE 677
Query: 179 R 181
R
Sbjct: 678 R 678
[142][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 54.3 bits (129), Expect = 4e-06
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+ T+ +K+ YN N+ VA LCNH RT+ + H QM+KL
Sbjct: 655 FRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGD 714
Query: 179 R 181
R
Sbjct: 715 R 715
[143][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 54.3 bits (129), Expect = 4e-06
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+ T+ +K+ YN N+ VA LCNH RT+ + H QM+KL
Sbjct: 655 FRTYNASYTMATLLKDLKSTGTIAEKIKDYNDANRKVAILCNHKRTVTASHASQMEKLGD 714
Query: 179 R 181
R
Sbjct: 715 R 715
[144][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 54.3 bits (129), Expect = 4e-06
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E T +KV +N N+ VA LCNH RT+ H +QK+
Sbjct: 597 FRTYNASKTMQDQLDLIPNEGTAAEKVVKFNAANRTVAILCNHQRTVSKNHGNSVQKIND 656
Query: 179 RRAEAVAWVKELKRGLAK 232
+ E + LK+ + K
Sbjct: 657 KLRELIWQKIRLKKMILK 674
[145][TOP]
>UniRef100_B4FTK0 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B4FTK0_MAIZE
Length = 269
Score = 54.3 bits (129), Expect = 4e-06
Identities = 44/116 (37%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Frame = -3
Query: 410 PACSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYS- 234
P SSA P PP +P P+ SS+P S A PA T P + P + P S
Sbjct: 137 PTPSSAPLPSPPSPPAAAPAPATSPSSSPPSSAAPAATPTSPTSPALAPAPAPTTTPSSP 196
Query: 233 ------TWPAHA*APLPTQRPRHGGSP---ASASGPCAHWAASARGCTVPPPPCSA 93
T P+ AP PT P GGSP ASAS P A +S T PP P +A
Sbjct: 197 PAPVPTTTPSSPPAPTPT-TPAGGGSPPPTASASAPAAEGGSS----TTPPQPSTA 247
[146][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 53.9 bits (128), Expect = 5e-06
Identities = 26/62 (41%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L +P +T +K+ YN+ N+ VA LCNH R++P H M+ L+
Sbjct: 814 FRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLK 873
Query: 176 TR 181
+
Sbjct: 874 AK 875
[147][TOP]
>UniRef100_Q8WZF2 Topoisomerase I (Fragment) n=1 Tax=Filobasidiella neoformans
RepID=Q8WZF2_CRYNE
Length = 270
Score = 53.9 bits (128), Expect = 5e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G K E
Sbjct: 62 FRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAED 121
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD--EKA 352
+ A+ + + LK L ++ K K P V E +E A+ EKA
Sbjct: 122 -KIRALKY-QRLKLRLQLFSLNPKIKK-----KHPELAEDESDVDDEFMERHEAELLEKA 174
Query: 353 QER-KRAADLPKVPLLKSMRGDQLKSNLK-RAEERLAKLTSDME 478
E K+ D V L GD K K +ERL+++ ++ +
Sbjct: 175 LENAKKKWDTDNVKL----EGDGKKKKTKGELDERLSEIKAEFK 214
[148][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 53.9 bits (128), Expect = 5e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G K E
Sbjct: 629 FRTYNASWTFQEQLKNTPKNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAED 688
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD--EKA 352
+ A+ + + LK L ++ K K P V E +E A+ EKA
Sbjct: 689 -KIRALKY-QRLKLRLQLFSLNPKIKK-----KHPELAEDESDVDDEFMERHEAELLEKA 741
Query: 353 QER-KRAADLPKVPLLKSMRGDQLKSNLK-RAEERLAKLTSDME 478
E K+ D V L GD K K +ERL+++ ++ +
Sbjct: 742 LENAKKKWDTDNVKL----EGDGKKKKTKGELDERLSEIKAEFK 781
[149][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 53.9 bits (128), Expect = 5e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T E L+ P TV +K+A YN N+ VA LCNH +++ G +G K E
Sbjct: 592 FRTYNASWTFQEQLKNTPTNGTVAEKIAAYNTANRDVAILCNHQKSVSKGFEGSFAKAED 651
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTAD--EKA 352
+ A+ + + LK L ++ K K P V E +E A+ EKA
Sbjct: 652 -KIRALKY-QRLKLRLQLFSLNPKIKK-----KHPELAEDESDVDDEFMERHEAELLEKA 704
Query: 353 QER-KRAADLPKVPLLKSMRGDQLKSNLK-RAEERLAKLTSDME 478
E K+ D V L GD K K +ERL+++ ++ +
Sbjct: 705 LENAKKKWDTDNVKL----EGDGKKKKTKGELDERLSEIKAEFK 744
[150][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 53.9 bits (128), Expect = 5e-06
Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E +V +KV YN N+ VA LCNH RT P H +Q++
Sbjct: 510 FRTYNASKTMQDQLDLIPNEGSVGEKVVKYNAANREVAILCNHQRTKPKSHDMGVQRISD 569
Query: 179 RRAEAVAWVKELKRGLAKWNKGGKGAK 259
E LKR + + +K K K
Sbjct: 570 NIRELFWQKLRLKRMILELDKSLKKTK 596
[151][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6H1W4_PENCW
Length = 864
Score = 53.9 bits (128), Expect = 5e-06
Identities = 28/62 (45%), Positives = 37/62 (59%), Gaps = 2/62 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS T+ L G T+ +KV YN N+ VA LCNH RT+ +GH M+K+
Sbjct: 609 FRTYNASYTMGCVLNEMNASGGTIAEKVKAYNDANRKVAILCNHKRTVTAGHANAMEKMG 668
Query: 176 TR 181
R
Sbjct: 669 ER 670
[152][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 53.9 bits (128), Expect = 5e-06
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+ +V +KV YN N+ VA LCNH RT+ + H QM+K+
Sbjct: 744 FRTYNASYTMATLLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSE 803
Query: 179 R 181
R
Sbjct: 804 R 804
[153][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 53.9 bits (128), Expect = 5e-06
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+A L+ +V +KV YN N+ VA LCNH RT+ + H QM+K+
Sbjct: 632 FRTYNASYTMATLLKDMKATGSVAEKVKAYNDANRRVAILCNHKRTVTASHANQMEKMSE 691
Query: 179 R 181
R
Sbjct: 692 R 692
[154][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 53.9 bits (128), Expect = 5e-06
Identities = 34/91 (37%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ P E + K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 589 FRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 648
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 268
T+ + K LA + K AKA A
Sbjct: 649 TK-------IDAKKEQLADARRDLKSAKADA 672
[155][TOP]
>UniRef100_B6KLS9 Voltage gated chloride channel domain-containing protein n=1
Tax=Toxoplasma gondii ME49 RepID=B6KLS9_TOXGO
Length = 1779
Score = 53.9 bits (128), Expect = 5e-06
Identities = 37/130 (28%), Positives = 54/130 (41%)
Frame = -3
Query: 410 PACSSATAPWANPPPVFSPVPSHRQSSTPESQA*PACTG*PPQAEKTRHQPWRLSRPYST 231
P+ ++ P ++PP P PS S+P S + P+ + PP + P S P S+
Sbjct: 231 PSPPPSSPPSSSPPSSSPPSPSSPPPSSPPSSSSPSSSSPPPSSSPPSSSPPSSSSPSSS 290
Query: 230 WPAHA*APLPTQRPRHGGSPASASGPCAHWAASARGCTVPPPPCSACCKMPPCPSPSRQG 51
P + +P P P SP+ +S P S+ + PPP S PP SP
Sbjct: 291 SPPPSSSPPPPSPPSSSTSPSPSSPP------SSSPPSPSPPPSSPPSSSPPSSSPPSPP 344
Query: 50 HLGGTQPGSP 21
P SP
Sbjct: 345 SPSSPPPSSP 354
[156][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 53.5 bits (127), Expect = 7e-06
Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NASVTL E L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 479 FRTYNASVTLQEQLRALTRAEDSVAAKILSYNRANRAVAILCNHQRATPKTFEKSMQNLQ 538
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGK 250
+ V E K L + G K
Sbjct: 539 LKIEAKKKQVAEAKAELKQARAGHK 563
[157][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 53.5 bits (127), Expect = 7e-06
Identities = 31/65 (47%), Positives = 39/65 (60%), Gaps = 5/65 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 166
FRT+NAS T++ L DP TV +KV YN N+ VA LCNH RT+ + H+ QM
Sbjct: 650 FRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGASHEQQMA 709
Query: 167 KLETR 181
KL R
Sbjct: 710 KLGDR 714
[158][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 53.5 bits (127), Expect = 7e-06
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ---GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRTFNAS TL + L D G TV +K+ YN+ N+ VA LCNH R P + MQ L
Sbjct: 20 FRTFNASTTLQDQLNKLTSDDG-TVEEKILSYNRANRAVAILCNHQRAAPKTFEKSMQLL 78
Query: 173 ETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAAS 274
+ + + ++E ++ L + + K + +S
Sbjct: 79 QEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSS 112
[159][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 53.5 bits (127), Expect = 7e-06
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 8/115 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 575 FRTYNASITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 634
Query: 176 T----RRAEAVAWVKELK--RGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEI 322
T ++ + A +ELK + AK K K KA + V+ + +K E+
Sbjct: 635 TKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKKAVESKKKAVQRIEDQLMKLEV 689
[160][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 53.5 bits (127), Expect = 7e-06
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 8/115 (6%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL L+ E + K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 575 FRTYNASITLQAQLKELTSEEENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 634
Query: 176 T----RRAEAVAWVKELK--RGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEI 322
T ++ + A +ELK + AK K K KA + V+ + +K E+
Sbjct: 635 TKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKKAVESKKKAVQRIEDQLMKLEV 689
[161][TOP]
>UniRef100_Q6Y634 Type I topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q6Y634_TRYCR
Length = 664
Score = 53.5 bits (127), Expect = 7e-06
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP---GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + P +V DK+A++NK N VA LCNH +++ H M +L
Sbjct: 412 FRTYNASITLDRWFKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHHNLMHQL 471
Query: 173 ETRRAEAVAWVKELKR 220
+ + + LKR
Sbjct: 472 TQKSSYTRTIIDALKR 487
[162][TOP]
>UniRef100_Q4Q2K0 DNA topoisomerase IB, large subunit n=1 Tax=Leishmania major
RepID=Q4Q2K0_LEIMA
Length = 634
Score = 53.5 bits (127), Expect = 7e-06
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 3/156 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG---DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + DP + DK+A++NK N VA LCNH +++ K QM +L
Sbjct: 409 FRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQL 468
Query: 173 ETRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILESMTADEKA 352
T+ + ++ L K K A+ +E M + E LES +E+
Sbjct: 469 TTKS----EYTRKTLELLEKAEVTAKKKSVEEAAKEFLEEQDRM--QREWLESYGTEEQK 522
Query: 353 QERKRAADLPKVPLLKSMRGDQLKSNLKRAEERLAK 460
+E + P ++S + + S K+A+ K
Sbjct: 523 KEFEEIVAKRAAPRVRSEK--KSSSGTKKAKSASGK 556
[163][TOP]
>UniRef100_Q4DTW1 DNA topoisomerase IB, large subunit, putative n=1 Tax=Trypanosoma
cruzi RepID=Q4DTW1_TRYCR
Length = 664
Score = 53.5 bits (127), Expect = 7e-06
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDP---GETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKL 172
FRT+NAS+TL + P +V DK+A++NK N VA LCNH +++ H M +L
Sbjct: 412 FRTYNASITLDRWFKEKPVPPSASVADKLAYFNKANTEVAILCNHQKSISKNHHNLMHQL 471
Query: 173 ETRRAEAVAWVKELKR 220
+ + + LKR
Sbjct: 472 TQKSSYTRTIIDALKR 487
[164][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 53.5 bits (127), Expect = 7e-06
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS TL + L + +++ +K+ YN+ N+ VA LCNH R++P H M+KL+
Sbjct: 84 FRTYNASWTLQQQLDELTNADDSLAEKILSYNRANRAVAILCNHQRSVPKSHAKSMEKLK 143
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGK 250
+ + + + +R + K K
Sbjct: 144 EKIDQKREQIADAQRQVKDAQKDAK 168
[165][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 53.5 bits (127), Expect = 7e-06
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + + P E TV +KV YN N+ VA LCNH RT+ H+ + K++
Sbjct: 512 FRTYNASKTMQDQMDLIPNEGTVAEKVMKYNAANRTVAILCNHQRTVSKAHQNSVGKIQE 571
Query: 179 RRAEAVAWVK 208
+ E + W K
Sbjct: 572 KIKE-MEWQK 580
[166][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 53.5 bits (127), Expect = 7e-06
Identities = 31/65 (47%), Positives = 39/65 (60%), Gaps = 5/65 (7%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ---GDPGE--TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 166
FRT+NAS T++ L DP TV +KV YN N+ VA LCNH RT+ + H+ QM
Sbjct: 649 FRTYNASFTMSTLLNKLGSDPRSRGTVAEKVKLYNDCNREVAILCNHKRTVGASHEQQMA 708
Query: 167 KLETR 181
KL R
Sbjct: 709 KLGDR 713
[167][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 53.1 bits (126), Expect = 9e-06
Identities = 30/70 (42%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ H +QK+
Sbjct: 537 FRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHD 596
Query: 179 RRAEAVAWVK 208
+ E + W K
Sbjct: 597 KLKE-LEWHK 605
[168][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 53.1 bits (126), Expect = 9e-06
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 397 FRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 456
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K K AKA +S + + + VK + ++
Sbjct: 457 TK-------IDEKQKQLSAARKQLKAAKAEHKASHDDKSKKAVEVKRKAVQ 500
[169][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 53.1 bits (126), Expect = 9e-06
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 629 FRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 688
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K K AKA +S + + + VK + ++
Sbjct: 689 TK-------IDEKQKQLSAARKQLKAAKAEHKASHDDKSKKAVEVKRKAVQ 732
[170][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 53.1 bits (126), Expect = 9e-06
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 591 FRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 650
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K K AKA +S + + + VK + ++
Sbjct: 651 TK-------IDEKQKQLSAARKQLKAAKAEHKASHDDKSKKAVEVKRKAVQ 694
[171][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 53.1 bits (126), Expect = 9e-06
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQ--GDPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ ++V K+ YN+ N+ VA LCNH R P + MQ L+
Sbjct: 591 FRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQ 650
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGAASSPPVEVTQYMPVKPEILE 328
T+ + E ++ L+ K K AKA +S + + + VK + ++
Sbjct: 651 TK-------IDEKQKQLSAARKQLKAAKAEHKASHDDKSKKAVEVKRKAVQ 694
[172][TOP]
>UniRef100_C5LJG7 DNA topoisomerase, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LJG7_9ALVE
Length = 551
Score = 53.1 bits (126), Expect = 9e-06
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Frame = +2
Query: 2 FRTFNASVTLA-ECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 166
FRT+NAS+TL E + DP E ++ V FYN N+ VA LCNH R P H+ M+
Sbjct: 461 FRTYNASITLEQELCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQHEAGME 520
Query: 167 KLETRRAEAVAWVKELK 217
+L+ + A+ A ++ L+
Sbjct: 521 RLKKKLADQEATLRGLE 537
[173][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 53.1 bits (126), Expect = 9e-06
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Frame = +2
Query: 2 FRTFNASVTLA-ECLQGDPGE----TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQ 166
FRT+NAS+TL E + DP E ++ V FYN N+ VA LCNH R P H+ M+
Sbjct: 461 FRTYNASITLEQELCKFDPEEHDISDPSEMVKFYNDANRRVAILCNHQRAPPKQHEAGME 520
Query: 167 KLETRRAEAVAWVKELK 217
+L+ + A+ A ++ L+
Sbjct: 521 RLKKKLADQEATLRGLE 537
[174][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 53.1 bits (126), Expect = 9e-06
Identities = 30/70 (42%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +2
Query: 2 FRTFNASVTLAECLQGDPGE-TVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLET 178
FRT+NAS T+ + L P E TV +KV +N N+ VA LCNH RT+ H +QK+
Sbjct: 537 FRTYNASKTMQDQLDLIPNEGTVAEKVVKFNAANRTVAILCNHQRTVSKTHGSSVQKIHD 596
Query: 179 RRAEAVAWVK 208
+ E + W K
Sbjct: 597 KLKE-LEWHK 605
[175][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 53.1 bits (126), Expect = 9e-06
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 2 FRTFNASVTLAECLQG--DPGETVTDKVAFYNKQNKVVAELCNHVRTLPSGHKGQMQKLE 175
FRT+NAS+TL + L+ P E V K+ YN+ N+ VA LCNH R P + M L+
Sbjct: 591 FRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQ 650
Query: 176 TRRAEAVAWVKELKRGLAKWNKGGKGAKAGA 268
++ + K LA K K AKA A
Sbjct: 651 SK-------IDAKKDQLADARKDLKSAKADA 674