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[1][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 142 bits (359), Expect(2) = 6e-40
Identities = 72/91 (79%), Positives = 77/91 (84%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSALA
Sbjct: 250 FCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALA 309
Query: 338 ILKNLGLIEETSIPRT----RPANAIQAKED 258
IL NLGLIEE+ I R P N +AKED
Sbjct: 310 ILMNLGLIEESKITRALPWRPPTNVFRAKED 340
Score = 45.8 bits (107), Expect(2) = 6e-40
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 232 VPGIMPINNYKGFLRMTGFCKTK 254
[2][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 142 bits (359), Expect(2) = 1e-39
Identities = 70/91 (76%), Positives = 79/91 (86%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP E+MAALEPIKDNEEAVKAYGIHLGTEMCKK+LAHG K+LHLYTLN+EKSALA
Sbjct: 236 FCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALA 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLG+I+E+ S+P RPAN + KED
Sbjct: 296 ILMNLGMIDESKISRSLPWRRPANVFRTKED 326
Score = 44.7 bits (104), Expect(2) = 1e-39
Identities = 18/23 (78%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNY+GF+RMTGF K +
Sbjct: 218 VPGIMPINNYRGFLRMTGFCKTK 240
[3][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 141 bits (355), Expect(2) = 2e-39
Identities = 70/91 (76%), Positives = 77/91 (84%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSALA
Sbjct: 236 FCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALA 295
Query: 338 ILKNLGLIEETSI----PRTRPANAIQAKED 258
IL NLGLIEE+ I P RP N + KED
Sbjct: 296 ILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 2e-39
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[4][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 141 bits (355), Expect(2) = 2e-39
Identities = 70/91 (76%), Positives = 77/91 (84%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSALA
Sbjct: 236 FCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALA 295
Query: 338 ILKNLGLIEETSI----PRTRPANAIQAKED 258
IL NLGLIEE+ I P RP N + KED
Sbjct: 296 ILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 2e-39
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 140 bits (354), Expect(2) = 5e-39
Identities = 71/91 (78%), Positives = 76/91 (83%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSALA
Sbjct: 247 FCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALA 306
Query: 338 ILKNLGLIEETSI----PRTRPANAIQAKED 258
IL NLGLIEE+ I P P N + KED
Sbjct: 307 ILMNLGLIEESKITRPLPWRPPTNVFRVKED 337
Score = 44.7 bits (104), Expect(2) = 5e-39
Identities = 19/23 (82%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGFIRM GF K +
Sbjct: 229 VPGIMPINNYKGFIRMAGFCKTK 251
[6][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 138 bits (347), Expect(2) = 1e-38
Identities = 70/91 (76%), Positives = 76/91 (83%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAEI AAL+PIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK+ALA
Sbjct: 224 FCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALA 283
Query: 338 ILKNLGLIEETSIPRT----RPANAIQAKED 258
IL NLGLIEE+ + RT P N + KED
Sbjct: 284 ILMNLGLIEESKLSRTLPWRPPTNVFRVKED 314
Score = 46.2 bits (108), Expect(2) = 1e-38
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 206 VPGIMPINNYKGFVRMTGFCKTK 228
[7][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 137 bits (346), Expect(2) = 2e-38
Identities = 69/90 (76%), Positives = 75/90 (83%), Gaps = 4/90 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKI+AHG KTLHLYTLN+EKSALA
Sbjct: 251 FCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLYTLNMEKSALA 310
Query: 338 ILKNLGLIEETSI----PRTRPANAIQAKE 261
IL NLGLIEE+ I P P N + KE
Sbjct: 311 ILMNLGLIEESKISRPLPWRPPTNVFRVKE 340
Score = 45.8 bits (107), Expect(2) = 2e-38
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 233 VPGIMPINNYKGFLRMTGFCKTK 255
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 137 bits (346), Expect(2) = 2e-38
Identities = 71/91 (78%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL
Sbjct: 236 FCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALG 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLIEE+ S+P P N + KED
Sbjct: 296 ILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 2e-38
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[9][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 137 bits (346), Expect(2) = 2e-38
Identities = 71/91 (78%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL
Sbjct: 236 FCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALG 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLIEE+ S+P P N + KED
Sbjct: 296 ILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 2e-38
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[10][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 135 bits (341), Expect(2) = 4e-38
Identities = 68/83 (81%), Positives = 72/83 (86%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPA+IMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG TLHLYTLN+EKSALA
Sbjct: 237 FCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALA 296
Query: 338 ILKNLGLIEETSIPRTRPANAIQ 270
IL NLGLIEET +A+Q
Sbjct: 297 ILMNLGLIEETKFLGPYLGDALQ 319
Score = 46.6 bits (109), Expect(2) = 4e-38
Identities = 20/23 (86%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGFIRMTGF K +
Sbjct: 219 VPGIMPINNYKGFIRMTGFCKTK 241
[11][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 134 bits (338), Expect(2) = 3e-37
Identities = 68/91 (74%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+EI AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSAL
Sbjct: 236 FCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALG 295
Query: 338 ILKNLGLIEETSIPRTRP----ANAIQAKED 258
IL NLGLI+ T I R P N ++ KE+
Sbjct: 296 ILANLGLIDMTKIRRPLPWRPATNVLRTKEN 326
Score = 44.7 bits (104), Expect(2) = 3e-37
Identities = 19/23 (82%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGFIRM GF K +
Sbjct: 218 VPGIMPINNYKGFIRMAGFCKTK 240
[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 130 bits (327), Expect(2) = 3e-36
Identities = 65/91 (71%), Positives = 73/91 (80%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+EI AAL+PIKDNEEAVK YGIHLGTEMCKKILA G KTLHLYTLN++KSA+
Sbjct: 236 FCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIG 295
Query: 338 ILKNLGLIEETSIPRTRP----ANAIQAKED 258
IL NLGLIEE+ + R P N + KED
Sbjct: 296 ILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 3e-36
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[13][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 129 bits (324), Expect(2) = 6e-36
Identities = 64/91 (70%), Positives = 73/91 (80%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+EI AAL+PIKDNEEAV+ YGIHLGTEMCKKILA G KTLHLYTLN++KSA+
Sbjct: 236 FCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIG 295
Query: 338 ILKNLGLIEETSIPRTRP----ANAIQAKED 258
IL NLGLIEE+ + R P N + KED
Sbjct: 296 ILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
Score = 45.8 bits (107), Expect(2) = 6e-36
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[14][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 132 bits (333), Expect(2) = 8e-36
Identities = 65/91 (71%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 236 FCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIG 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLI+E+ S+P RPAN + KED
Sbjct: 296 ILMNLGLIDESKISRSLPWRRPANVFRTKED 326
Score = 42.0 bits (97), Expect(2) = 8e-36
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI+NYKGF+RM GF K +
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTK 240
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 132 bits (333), Expect(2) = 8e-36
Identities = 65/91 (71%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 236 FCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIG 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLI+E+ S+P RPAN + KED
Sbjct: 296 ILMNLGLIDESKISRSLPWRRPANVFRTKED 326
Score = 42.0 bits (97), Expect(2) = 8e-36
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI+NYKGF+RM GF K +
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTK 240
[16][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 132 bits (333), Expect(2) = 8e-36
Identities = 65/91 (71%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 236 FCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIG 295
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLI+E+ S+P RPAN + KED
Sbjct: 296 ILMNLGLIDESKISRSLPWRRPANVFRTKED 326
Score = 42.0 bits (97), Expect(2) = 8e-36
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI+NYKGF+RM GF K +
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTK 240
[17][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 132 bits (333), Expect(2) = 8e-36
Identities = 65/91 (71%), Positives = 75/91 (82%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+
Sbjct: 46 FCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIG 105
Query: 338 ILKNLGLIEET----SIPRTRPANAIQAKED 258
IL NLGLI+E+ S+P RPAN + KED
Sbjct: 106 ILMNLGLIDESKISRSLPWRRPANVFRTKED 136
Score = 42.0 bits (97), Expect(2) = 8e-36
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI+NYKGF+RM GF K +
Sbjct: 28 VPGIMPISNYKGFLRMAGFCKTK 50
[18][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 127 bits (318), Expect(2) = 6e-33
Identities = 63/90 (70%), Positives = 73/90 (81%), Gaps = 4/90 (4%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
CKTK+PAEIMAALEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L I
Sbjct: 237 CKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGI 296
Query: 335 LKNLGLIE----ETSIPRTRPANAIQAKED 258
L+NLGLI+ +P P N+ + KED
Sbjct: 297 LQNLGLIDFSRVSRPLPWRPPTNSKRTKED 326
Score = 38.1 bits (87), Expect(2) = 6e-33
Identities = 16/23 (69%), Positives = 18/23 (78%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI NYKGF+RMT K +
Sbjct: 218 VPGIMPIQNYKGFLRMTTLCKTK 240
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 125 bits (315), Expect(2) = 8e-33
Identities = 62/90 (68%), Positives = 73/90 (81%), Gaps = 4/90 (4%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
CKTK+PAEIMA LEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L I
Sbjct: 237 CKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGI 296
Query: 335 LKNLGLIEETSI----PRTRPANAIQAKED 258
L+NLGLI+ + + P P N+ + KED
Sbjct: 297 LQNLGLIDFSKVTRPLPWRPPTNSKRTKED 326
Score = 38.9 bits (89), Expect(2) = 8e-33
Identities = 16/23 (69%), Positives = 18/23 (78%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI NYKGF+RMT K +
Sbjct: 218 VPGIMPIQNYKGFLRMTSLCKTK 240
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 107 bits (268), Expect(2) = 2e-29
Identities = 59/91 (64%), Positives = 67/91 (73%), Gaps = 4/91 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT L T++L
Sbjct: 236 FCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTFGL-TMDLP----- 289
Query: 338 ILKNLGLIEETSI----PRTRPANAIQAKED 258
+NLGLIEE+ I P RP N + KED
Sbjct: 290 -WQNLGLIEESKISRPFPWRRPTNVFRVKED 319
Score = 45.8 bits (107), Expect(2) = 2e-29
Identities = 19/23 (82%), Positives = 21/23 (91%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPINNYKGF+RMTGF K +
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTK 240
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 100 bits (248), Expect(2) = 7e-24
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 1/85 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSAL 342
FCKTK+PAEI ALE IKDN+EAVKAYGI LG MC+++LA G +H+YTLNLEKSA+
Sbjct: 230 FCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAV 289
Query: 341 AILKNLGLIEETSIPRTRPANAIQA 267
AIL+ LGL++ + + R P + A
Sbjct: 290 AILEQLGLVDTSRVQRPLPWRHVPA 314
Score = 34.7 bits (78), Expect(2) = 7e-24
Identities = 15/23 (65%), Positives = 17/23 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y GF RMTGF K +
Sbjct: 212 LPGIMPIMTYGGFKRMTGFCKTK 234
[22][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 75.9 bits (185), Expect(2) = 3e-16
Identities = 37/66 (56%), Positives = 46/66 (69%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
KTK+P IM LEPIKDN+E VK YG+ L EM K++L G + LH YTLNLE+S +L
Sbjct: 231 KTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVL 290
Query: 332 KNLGLI 315
K L L+
Sbjct: 291 KGLQLV 296
Score = 33.1 bits (74), Expect(2) = 3e-16
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y GF+RMT K +
Sbjct: 211 IPGIMPIQTYAGFVRMTTLSKTK 233
[23][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 72.0 bits (175), Expect(2) = 2e-14
Identities = 34/67 (50%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSAL 342
FCKT++P + A +E IKD+ AVKA+G+ G EMC+ +LA G LH YTLNLEK
Sbjct: 310 FCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEKVVY 369
Query: 341 AILKNLG 321
+L LG
Sbjct: 370 GVLDALG 376
Score = 31.2 bits (69), Expect(2) = 2e-14
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPG+M IN Y GF++M F K R
Sbjct: 292 VPGLMCINAYAGFVKMAKFCKTR 314
[24][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 68.2 bits (165), Expect(2) = 1e-13
Identities = 34/76 (44%), Positives = 47/76 (61%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K KIP M ALEP+K+++ AVK G L +EMC+K+L +G LH YT+NL +S +L
Sbjct: 229 KCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQSTTMVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L L T P +P
Sbjct: 289 EELNLKPSTETPLQKP 304
Score = 32.3 bits (72), Expect(2) = 1e-13
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y FIR T +VK
Sbjct: 209 IPGIMPISTYAAFIRRTNWVK 229
[25][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 70.1 bits (170), Expect(2) = 1e-13
Identities = 33/76 (43%), Positives = 49/76 (64%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AVK G L +MC+++LA G K LH YT+NL ++ A+L
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L LI P RP
Sbjct: 289 EELKLIPSEETPLQRP 304
Score = 30.4 bits (67), Expect(2) = 1e-13
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + K R
Sbjct: 209 IPGIMPISTYAAFIRRANWTKAR 231
[26][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 69.7 bits (169), Expect(2) = 2e-13
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ IL
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMIL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
LGLI P +P Q+ G +E
Sbjct: 289 DELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
Score = 30.0 bits (66), Expect(2) = 2e-13
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + + K R
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIR 231
[27][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 69.7 bits (169), Expect(2) = 2e-13
Identities = 37/90 (41%), Positives = 53/90 (58%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ IL
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMIL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
LGLI P +P Q+ G +E
Sbjct: 289 DELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
Score = 30.0 bits (66), Expect(2) = 2e-13
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + + K R
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIR 231
[28][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 69.3 bits (168), Expect(2) = 2e-13
Identities = 34/76 (44%), Positives = 47/76 (61%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP E + ALEP+K+++ AVK G L EMC+K+LA G LH YT+NL ++ ++L
Sbjct: 229 KARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQATQSVL 288
Query: 332 KNLGLIEETSIPRTRP 285
L LI P RP
Sbjct: 289 DELKLIPSEETPLQRP 304
Score = 30.4 bits (67), Expect(2) = 2e-13
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + K R
Sbjct: 209 IPGIMPISTYAAFIRRANWTKAR 231
[29][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 67.8 bits (164), Expect(2) = 2e-13
Identities = 32/45 (71%), Positives = 36/45 (80%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK 384
FCKTK+ A ALEPIKDNE+AV YGIHLGTEMCKK+L +G K
Sbjct: 15 FCKTKVTA----ALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK 55
Score = 31.6 bits (70), Expect(2) = 2e-13
Identities = 13/19 (68%), Positives = 15/19 (78%)
Frame = -1
Query: 559 MPINNYKGFIRMTGFVKQR 503
MPINN KGF+ MTGF K +
Sbjct: 1 MPINNSKGFLGMTGFCKTK 19
[30][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 68.2 bits (165), Expect(2) = 4e-13
Identities = 32/76 (42%), Positives = 48/76 (63%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+L
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L LI P RP
Sbjct: 289 EELKLIPSEETPLQRP 304
Score = 30.4 bits (67), Expect(2) = 4e-13
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + K R
Sbjct: 209 IPGIMPISTYAAFIRRANWTKAR 231
[31][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 68.2 bits (165), Expect(2) = 4e-13
Identities = 32/76 (42%), Positives = 48/76 (63%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+L
Sbjct: 229 KARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L LI P RP
Sbjct: 289 EELKLIPSEETPLQRP 304
Score = 30.4 bits (67), Expect(2) = 4e-13
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + K R
Sbjct: 209 IPGIMPISTYAAFIRRANWTKAR 231
[32][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 68.2 bits (165), Expect(2) = 5e-13
Identities = 36/90 (40%), Positives = 52/90 (57%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K ++P M ALEP K+++ AVK G L +EMC+KIL G + LH YT+NL +S +L
Sbjct: 229 KCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQSTKMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
+ L LI + P +P Q+ G +E
Sbjct: 289 EELDLIPSSETPLQKPLPWRQSLGLGRREE 318
Score = 30.0 bits (66), Expect(2) = 5e-13
Identities = 12/23 (52%), Positives = 17/23 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y F+R + +VK R
Sbjct: 209 LPGIMPISTYAAFLRRSNWVKCR 231
[33][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 71.6 bits (174), Expect(2) = 6e-13
Identities = 31/71 (43%), Positives = 50/71 (70%), Gaps = 1/71 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 342
+C+ +P MA L+P+KD+++AV+ G L +MC+K+L G+ T LH+YT+NLEK+ +
Sbjct: 230 WCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACI 289
Query: 341 AILKNLGLIEE 309
+L LGL+ E
Sbjct: 290 MVLDRLGLLSE 300
Score = 26.2 bits (56), Expect(2) = 6e-13
Identities = 9/19 (47%), Positives = 13/19 (68%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGF 515
+PGIMPI Y F+R + +
Sbjct: 212 IPGIMPITTYAAFLRRSSW 230
[34][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 67.0 bits (162), Expect(2) = 6e-13
Identities = 29/67 (43%), Positives = 42/67 (62%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCKT++P + ++ IKD+ +AVK +G+ G E+ + +L G K LH YTLNLEK
Sbjct: 249 FCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKILHFYTLNLEKVVYG 308
Query: 338 ILKNLGL 318
I LG+
Sbjct: 309 ITDELGI 315
Score = 30.8 bits (68), Expect(2) = 6e-13
Identities = 14/23 (60%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPG+M IN Y GF +MT F K R
Sbjct: 231 VPGLMCINAYPGFKKMTKFCKTR 253
[35][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 66.6 bits (161), Expect(2) = 1e-12
Identities = 34/82 (41%), Positives = 52/82 (63%), Gaps = 2/82 (2%)
Frame = -3
Query: 524 DWFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSA 345
DW KT+IP + + ALEP+K+++ AV+ G L +MC++++A G LH YT+NL +S
Sbjct: 226 DW-TKTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQST 284
Query: 344 LAILKNLGLI--EETSIPRTRP 285
+L L L+ EET + R P
Sbjct: 285 QLVLDELNLMPSEETPLQRALP 306
Score = 30.0 bits (66), Expect(2) = 1e-12
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y FIR + + K R
Sbjct: 209 IPGIMPIQTYAAFIRRSDWTKTR 231
[36][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 72.0 bits (175), Expect(2) = 2e-12
Identities = 34/70 (48%), Positives = 52/70 (74%), Gaps = 1/70 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 342
+C+ ++P E + LEP+KD+++AV+ G L +MC+KILA G T LHLYT+NLE+++L
Sbjct: 230 WCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASL 289
Query: 341 AILKNLGLIE 312
IL+ L LI+
Sbjct: 290 MILERLQLID 299
Score = 24.3 bits (51), Expect(2) = 2e-12
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI +Y +R + + R
Sbjct: 212 IPGIMPITSYAALLRRAKWCQVR 234
[37][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 63.5 bits (153), Expect(2) = 3e-12
Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLYTLNL 357
FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH YTLNL
Sbjct: 201 FCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNL 260
Query: 356 EKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 237
E S I++ L +++ R P +A E RP
Sbjct: 261 ESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
Score = 32.0 bits (71), Expect(2) = 3e-12
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMTGFVKQR 503
PGIMPI +Y GF +MT F K +
Sbjct: 184 PGIMPIQSYSGFKKMTEFCKTK 205
[38][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 67.0 bits (162), Expect(2) = 3e-12
Identities = 32/76 (42%), Positives = 47/76 (61%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
KT IP + + ALEP+K+++ AVK G L +MC++++A G K LH YT+NL +S +L
Sbjct: 229 KTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L L P RP
Sbjct: 289 EELELTPTAEAPIPRP 304
Score = 28.5 bits (62), Expect(2) = 3e-12
Identities = 11/21 (52%), Positives = 13/21 (61%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI Y FIR + K
Sbjct: 209 IPGIMPIQTYAAFIRRANWTK 229
[39][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 66.6 bits (161), Expect(2) = 3e-12
Identities = 32/76 (42%), Positives = 47/76 (61%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K K+P+E M ALEP+K+++ AV+ G L MC++++A G K LH YT+NL ++ +L
Sbjct: 229 KVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVL 288
Query: 332 KNLGLIEETSIPRTRP 285
K L L P RP
Sbjct: 289 KELELTPSEDSPIQRP 304
Score = 28.9 bits (63), Expect(2) = 3e-12
Identities = 11/21 (52%), Positives = 14/21 (66%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI Y FIR + + K
Sbjct: 209 IPGIMPIQTYASFIRRSNWTK 229
[40][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 63.5 bits (153), Expect(2) = 3e-12
Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLYTLNL 357
FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH YTLNL
Sbjct: 201 FCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFYTLNL 260
Query: 356 EKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 237
E S I++ L +++ R P +A E RP
Sbjct: 261 ESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
Score = 32.0 bits (71), Expect(2) = 3e-12
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMTGFVKQR 503
PGIMPI +Y GF +MT F K +
Sbjct: 184 PGIMPIQSYSGFKKMTEFCKTK 205
[41][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 65.9 bits (159), Expect(2) = 4e-12
Identities = 35/90 (38%), Positives = 51/90 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
LGLI P +P Q+ G +E
Sbjct: 289 DELGLIPSHETPLQKPLPWRQSLGLGRREE 318
Score = 29.3 bits (64), Expect(2) = 4e-12
Identities = 11/21 (52%), Positives = 15/21 (71%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y FIR + + K
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTK 229
[42][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 65.9 bits (159), Expect(2) = 4e-12
Identities = 35/90 (38%), Positives = 51/90 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
LGLI P +P Q+ G +E
Sbjct: 289 DELGLIPSHETPLQKPLPWRQSLGLGRREE 318
Score = 29.3 bits (64), Expect(2) = 4e-12
Identities = 11/21 (52%), Positives = 15/21 (71%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y FIR + + K
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTK 229
[43][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 65.9 bits (159), Expect(2) = 4e-12
Identities = 35/90 (38%), Positives = 51/90 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L
Sbjct: 229 KIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
LGLI P +P Q+ G +E
Sbjct: 289 DELGLIPSHETPLQKPLPWRQSLGLGRREE 318
Score = 29.3 bits (64), Expect(2) = 4e-12
Identities = 11/21 (52%), Positives = 15/21 (71%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y FIR + + K
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTK 229
[44][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 72.4 bits (176), Expect(2) = 4e-12
Identities = 32/70 (45%), Positives = 46/70 (65%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
KIP M L P+KD++E V+ G+ L EMC+K++A G LH YT+NLEK+ I++
Sbjct: 231 KIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIER 290
Query: 326 LGLIEETSIP 297
LGL++E P
Sbjct: 291 LGLLDENLAP 300
Score = 22.7 bits (47), Expect(2) = 4e-12
Identities = 9/14 (64%), Positives = 10/14 (71%)
Frame = -1
Query: 568 PGIMPINNYKGFIR 527
PGIMPI + FIR
Sbjct: 210 PGIMPIQAWDSFIR 223
[45][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 63.5 bits (153), Expect(2) = 7e-12
Identities = 30/67 (44%), Positives = 43/67 (64%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALA 339
FCK++ PA + AA+E D++EA++ + G ++C+ + A G LH YTLNLEK LA
Sbjct: 260 FCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAGAPGLHFYTLNLEKVTLA 319
Query: 338 ILKNLGL 318
IL L L
Sbjct: 320 ILDALNL 326
Score = 30.8 bits (68), Expect(2) = 7e-12
Identities = 15/23 (65%), Positives = 15/23 (65%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIM I N GF RMT F K R
Sbjct: 242 VPGIMCIQNAGGFKRMTAFCKSR 264
[46][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 73.9 bits (180), Expect = 8e-12
Identities = 36/66 (54%), Positives = 46/66 (69%), Gaps = 1/66 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K IP EI +EPIKDN+ A++ YGI L T+MC+ +L G LH+YTLNLE + + I
Sbjct: 245 KLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLETATIQI 304
Query: 335 LKNLGL 318
LKNLGL
Sbjct: 305 LKNLGL 310
[47][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 65.1 bits (157), Expect(2) = 8e-12
Identities = 34/68 (50%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTL---HLYTLNLEKS 348
+C +P EI LEPIKD++EAVK G L EMC++ILA + H YTLNLE+S
Sbjct: 253 YCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNLERS 312
Query: 347 ALAILKNL 324
A IL L
Sbjct: 313 ATRILMQL 320
Score = 28.9 bits (63), Expect(2) = 8e-12
Identities = 11/19 (57%), Positives = 14/19 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGF 515
+PGIMPI +Y F RMT +
Sbjct: 235 LPGIMPIQSYSSFTRMTQY 253
[48][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 64.7 bits (156), Expect(2) = 8e-12
Identities = 32/76 (42%), Positives = 45/76 (59%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +L
Sbjct: 229 KCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L LI P +P
Sbjct: 289 EELKLIPSYETPLQKP 304
Score = 29.3 bits (64), Expect(2) = 8e-12
Identities = 11/21 (52%), Positives = 16/21 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y F+R + +VK
Sbjct: 209 LPGIMPISTYASFLRRSNWVK 229
[49][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 64.7 bits (156), Expect(2) = 8e-12
Identities = 32/76 (42%), Positives = 45/76 (59%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +L
Sbjct: 229 KCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L LI P +P
Sbjct: 289 EELKLIPSYETPLQKP 304
Score = 29.3 bits (64), Expect(2) = 8e-12
Identities = 11/21 (52%), Positives = 16/21 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI+ Y F+R + +VK
Sbjct: 209 LPGIMPISTYASFLRRSNWVK 229
[50][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 65.5 bits (158), Expect(2) = 8e-12
Identities = 28/74 (37%), Positives = 51/74 (68%), Gaps = 1/74 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSAL 342
+C+ +P + LEP+KD+++ V+ G L E+C+K+L G+ LH+YT+NLEK++L
Sbjct: 232 WCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLEKASL 291
Query: 341 AILKNLGLIEETSI 300
IL+ L L++ +++
Sbjct: 292 MILEKLDLLKRSNV 305
Score = 28.5 bits (62), Expect(2) = 8e-12
Identities = 11/17 (64%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI +Y FIR T
Sbjct: 214 IPGIMPITSYPSFIRRT 230
[51][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 63.5 bits (153), Expect(2) = 1e-11
Identities = 34/90 (37%), Positives = 51/90 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++ +L
Sbjct: 229 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
L LI P +P Q+ G +E
Sbjct: 289 GELELIPSHKTPLQKPLPWRQSLGLGRREE 318
Score = 30.0 bits (66), Expect(2) = 1e-11
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + + K R
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIR 231
[52][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 63.5 bits (153), Expect(2) = 1e-11
Identities = 34/90 (37%), Positives = 51/90 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++ +L
Sbjct: 120 KIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVL 179
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
L LI P +P Q+ G +E
Sbjct: 180 GELELIPSHKTPLQKPLPWRQSLGLGRREE 209
Score = 30.0 bits (66), Expect(2) = 1e-11
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y FIR + + K R
Sbjct: 100 IPGIMPIHTYAAFIRRSNWTKIR 122
[53][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 67.4 bits (163), Expect(2) = 1e-11
Identities = 37/95 (38%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILK 330
KIP + LEP+KD+++ V+ G L +MC+KIL G+ K LH+YT+NLEK+ L IL+
Sbjct: 236 KIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILE 295
Query: 329 NLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 225
LGL+ S P ++ ++ N +R E++
Sbjct: 296 KLGLLPSESEVNANPLASLPWRK-SLNPKRKNEEV 329
Score = 25.8 bits (55), Expect(2) = 1e-11
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 214 IPGIMPITTYAAFLR 228
[54][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 64.7 bits (156), Expect(2) = 2e-11
Identities = 31/76 (40%), Positives = 46/76 (60%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K +IP E + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +S +L
Sbjct: 229 KIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L L P +P
Sbjct: 289 EELNLTPSEETPLQKP 304
Score = 28.1 bits (61), Expect(2) = 2e-11
Identities = 11/23 (47%), Positives = 14/23 (60%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y F+R + K R
Sbjct: 209 IPGIMPIQTYAAFMRRANWTKIR 231
[55][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 63.5 bits (153), Expect(2) = 9e-11
Identities = 31/65 (47%), Positives = 45/65 (69%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE++ + IL+N
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILEN 291
Query: 326 LGLIE 312
L LIE
Sbjct: 292 LNLIE 296
Score = 26.9 bits (58), Expect(2) = 9e-11
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 209 IPGIMPISTYAAFIR 223
[56][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 63.5 bits (153), Expect(2) = 9e-11
Identities = 31/65 (47%), Positives = 45/65 (69%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE++ + IL+N
Sbjct: 232 IPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILEN 291
Query: 326 LGLIE 312
L LIE
Sbjct: 292 LNLIE 296
Score = 26.9 bits (58), Expect(2) = 9e-11
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 209 IPGIMPISTYAAFIR 223
[57][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 63.2 bits (152), Expect(2) = 1e-10
Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 10/91 (10%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + AL+PIKD++ V+ G L +EMC+K+L G+ LH YT+NLEK+ + IL+
Sbjct: 232 IPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMILEK 291
Query: 326 LGLIEE---------TSIPRTRPANAIQAKE 261
L LIE T +P + N ++KE
Sbjct: 292 LNLIEAVKSNEIVGVTELPWRKSLNPERSKE 322
Score = 26.6 bits (57), Expect(2) = 1e-10
Identities = 9/15 (60%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y F+R
Sbjct: 209 IPGIMPISTYSAFLR 223
[58][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 62.4 bits (150), Expect(2) = 2e-10
Identities = 30/66 (45%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILK 330
KIP + ALEPIKD++ V+ G L +EMC++++ G+ LH YT+NLEK+ + IL+
Sbjct: 232 KIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLEKATVMILE 291
Query: 329 NLGLIE 312
L L+E
Sbjct: 292 KLNLVE 297
Score = 26.9 bits (58), Expect(2) = 2e-10
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 210 IPGIMPISTYAAFIR 224
[59][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/69 (47%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L MCK++LA G LH YTLN E + + +
Sbjct: 267 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEV 326
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 327 LKRLGMWNE 335
[60][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 60.1 bits (144), Expect(2) = 3e-10
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K IP + + LEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ +L
Sbjct: 229 KIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVL 288
Query: 332 KNLGLI--EETSIPRTRP 285
L L+ EET I R P
Sbjct: 289 DELKLLPSEETPIQRPLP 306
Score = 28.5 bits (62), Expect(2) = 3e-10
Identities = 11/21 (52%), Positives = 13/21 (61%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI Y FIR + K
Sbjct: 209 IPGIMPIQTYAAFIRRANWTK 229
[61][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 61.2 bits (147), Expect(2) = 4e-10
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLEK+ + IL+
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEK 291
Query: 326 LGLIE 312
L LIE
Sbjct: 292 LNLIE 296
Score = 26.9 bits (58), Expect(2) = 4e-10
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 209 IPGIMPISTYAAFIR 223
[62][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 61.2 bits (147), Expect(2) = 4e-10
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLEK+ + IL+
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEK 291
Query: 326 LGLIE 312
L LIE
Sbjct: 292 LNLIE 296
Score = 26.9 bits (58), Expect(2) = 4e-10
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 209 IPGIMPISTYAAFIR 223
[63][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 61.2 bits (147), Expect(2) = 4e-10
Identities = 31/72 (43%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH-GFKTLHLYTLNLEKSALA 339
C P +++ LEPIK ++ VK +GIHL +M K I G + HLYTLNLEKSA
Sbjct: 255 CGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLEKSATC 314
Query: 338 ILKNLGLIEETS 303
++K L + + S
Sbjct: 315 VIKVLADVPDQS 326
Score = 26.9 bits (58), Expect(2) = 4e-10
Identities = 11/16 (68%), Positives = 12/16 (75%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGIMPI NY F RM
Sbjct: 236 IPGIMPIQNYTMFRRM 251
[64][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 59.7 bits (143), Expect(2) = 4e-10
Identities = 30/67 (44%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Frame = -3
Query: 509 TKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL--AHGFKTLHLYTLNLEKSALAI 336
TKIP + ALEP+K ++E V+ G L +MC+KIL G + LH YT+NLEK +
Sbjct: 191 TKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEKGTRML 250
Query: 335 LKNLGLI 315
L+ L L+
Sbjct: 251 LEELNLV 257
Score = 28.5 bits (62), Expect(2) = 4e-10
Identities = 11/23 (47%), Positives = 14/23 (60%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI + GFI+ T +
Sbjct: 170 VPGIMPIQTWNGFIKATNLASTK 192
[65][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 336
K ++P EI A +EPIKDN+ A++ YGI L MC+++L G + LH YTLN E + + +
Sbjct: 270 KLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEV 329
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 330 LKRLGIWNE 338
[66][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 67.8 bits (164), Expect = 6e-10
Identities = 30/66 (45%), Positives = 42/66 (63%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C K+P+ +++ LE + DN+EA AYGI TE C ++L G LH+YTLN S + +
Sbjct: 236 CGAKLPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAPSTIQV 295
Query: 335 LKNLGL 318
LKNL L
Sbjct: 296 LKNLAL 301
[67][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 56.2 bits (134), Expect(2) = 7e-10
Identities = 31/66 (46%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LAHGFKTLHLYTLNLEKSALA 339
CK ++P I+ ALEPIK ++ AVK YG+ L M +I L + HL +LNLEKS
Sbjct: 291 CKVQVPQLILDALEPIKSDDAAVKEYGVSLSIHMVGRIFLETDVRGFHLCSLNLEKSIER 350
Query: 338 ILKNLG 321
IL+ LG
Sbjct: 351 ILEGLG 356
Score = 31.2 bits (69), Expect(2) = 7e-10
Identities = 13/21 (61%), Positives = 14/21 (66%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI NY F RMT K
Sbjct: 272 LPGIMPIQNYSSFRRMTNLCK 292
[68][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 60.1 bits (144), Expect(2) = 7e-10
Identities = 28/65 (43%), Positives = 44/65 (67%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + AL PIK+++ A++ G L +EMC+K++ G+ LH YT+NLE+S + IL+
Sbjct: 235 IPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEK 294
Query: 326 LGLIE 312
L L+E
Sbjct: 295 LNLVE 299
Score = 27.3 bits (59), Expect(2) = 7e-10
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y FIR
Sbjct: 212 IPGIMPISTYSAFIR 226
[69][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 61.6 bits (148), Expect(2) = 7e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 327
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 326 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 225
L ++ S P A+ N +R E++
Sbjct: 297 LNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
Score = 25.8 bits (55), Expect(2) = 7e-10
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 214 IPGIMPITTYAAFLR 228
[70][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 61.6 bits (148), Expect(2) = 7e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 327
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 326 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 225
L ++ S P A+ N +R E++
Sbjct: 297 LNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
Score = 25.8 bits (55), Expect(2) = 7e-10
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 214 IPGIMPITTYAAFLR 228
[71][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 335 LKNLGLIEE 309
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[72][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 335 LKNLGLIEE 309
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[73][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 335 LKNLGLIEE 309
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[74][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 61.2 bits (147), Expect(2) = 9e-10
Identities = 33/88 (37%), Positives = 49/88 (55%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
KIP E MA LEP+K+++ AV+ G L EMC+KI+ G + LH YT+NL ++ +L+
Sbjct: 231 KIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEE 290
Query: 326 LGLIEETSIPRTRPANAIQAKEDGENQE 243
L + + P R Q+ G E
Sbjct: 291 LDWLPSPNRPLKRALPWKQSLGSGRRDE 318
Score = 25.8 bits (55), Expect(2) = 9e-10
Identities = 10/15 (66%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y FIR
Sbjct: 209 IPGIMPIATYASFIR 223
[75][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 61.2 bits (147), Expect(2) = 9e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 327
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 326 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 225
L ++ S P A+ N +R E++
Sbjct: 297 LNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
Score = 25.8 bits (55), Expect(2) = 9e-10
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 214 IPGIMPITTYAAFLR 228
[76][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 61.2 bits (147), Expect(2) = 9e-10
Identities = 29/73 (39%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSAL 342
+C+ +IP + + LEP+KD++ V+ G L +MC+K+L G K LH YT+NLEK+ +
Sbjct: 228 WCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATV 287
Query: 341 AILKNLGLIEETS 303
+L+ L L + S
Sbjct: 288 MVLERLNLPAQDS 300
Score = 25.8 bits (55), Expect(2) = 9e-10
Identities = 9/15 (60%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y F+R
Sbjct: 210 IPGIMPISTYASFMR 224
[77][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 61.2 bits (147), Expect(2) = 9e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 327
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 48 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 107
Query: 326 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 225
L ++ S P A+ N +R E++
Sbjct: 108 LNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 140
Score = 25.8 bits (55), Expect(2) = 9e-10
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 25 IPGIMPITTYAAFLR 39
[78][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 67.0 bits (162), Expect = 9e-10
Identities = 33/69 (47%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI EMCK +LA G LH YTLN E + + +
Sbjct: 273 KLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEV 332
Query: 335 LKNLGLIEE 309
L+ LGL E
Sbjct: 333 LRQLGLWAE 341
[79][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/69 (47%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K ++P EI + LEPIKDN+ A++ YGI L EMC+ +L G LH YTLN E + + +
Sbjct: 277 KLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 335 LKNLGLIEE 309
L+ LGL E
Sbjct: 337 LRQLGLWTE 345
[80][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 59.7 bits (143), Expect(2) = 2e-09
Identities = 30/72 (41%), Positives = 44/72 (61%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
+ +IP E + LEPIK ++ AV+ G L E+C+KILA G LH YT+NL +S IL
Sbjct: 224 QARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALIL 283
Query: 332 KNLGLIEETSIP 297
++L + + P
Sbjct: 284 EDLDWLPSPNKP 295
Score = 26.6 bits (57), Expect(2) = 2e-09
Identities = 10/23 (43%), Positives = 14/23 (60%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y F+R ++ R
Sbjct: 204 IPGIMPIATYASFLRRANHMQAR 226
[81][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 59.7 bits (143), Expect(2) = 2e-09
Identities = 29/65 (44%), Positives = 42/65 (64%), Gaps = 1/65 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 327
IP + LEPIKD++ V+ G L ++MC K+L GF LH YT+NLE++ + IL+
Sbjct: 232 IPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMILET 291
Query: 326 LGLIE 312
L +IE
Sbjct: 292 LNIIE 296
Score = 26.6 bits (57), Expect(2) = 2e-09
Identities = 9/15 (60%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y F+R
Sbjct: 209 IPGIMPISTYAAFVR 223
[82][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 66.2 bits (160), Expect = 2e-09
Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 5/90 (5%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA-HGFKTLHLYTLNLEKSALAI 336
K +P I+ +E IKDN+EA++ +GI T +CKK+LA +H+YTLN E++ + +
Sbjct: 256 KLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKL 315
Query: 335 LKNLGLIEETSIPRTRP----ANAIQAKED 258
LK +GL E SI ++ P AN + ED
Sbjct: 316 LKRVGLWHEESIYKSLPWRPSANGKRISED 345
[83][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 56.2 bits (134), Expect(2) = 3e-09
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K +IP + + LEP+K ++ V+ G L EMC+K+LA G LH YT+NL ++ I
Sbjct: 229 KIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLAQATRLI 288
Query: 335 LKNLGLIEETSIPRTRP 285
L+ L L+ P +P
Sbjct: 289 LEELRLLPSEEAPLQKP 305
Score = 29.3 bits (64), Expect(2) = 3e-09
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
VPGIMPI+ Y F+R + + K R
Sbjct: 209 VPGIMPISTYDAFMRRSNWTKIR 231
[84][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 64.3 bits (155), Expect(2) = 3e-09
Identities = 36/89 (40%), Positives = 52/89 (58%), Gaps = 4/89 (4%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K +IP EI A+EPI+DN+EA++ YG+H M +++ G LH YTLN E + + I
Sbjct: 262 KLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQI 321
Query: 335 LKNLGLIEE---TSIPRTRPANAIQAKED 258
LK +GL E P R AN + +E+
Sbjct: 322 LKQIGLWTEDIQRPWPWKRTANYNRCEEE 350
Score = 20.8 bits (42), Expect(2) = 3e-09
Identities = 6/10 (60%), Positives = 8/10 (80%)
Frame = -1
Query: 571 VPGIMPINNY 542
+PG+MPI Y
Sbjct: 242 IPGVMPIQGY 251
[85][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 65.1 bits (157), Expect = 4e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 355
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 356 LKRLGMWTE 364
[86][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 65.1 bits (157), Expect = 4e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 373
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 374 LKRLGMWTE 382
[87][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 65.1 bits (157), Expect = 4e-09
Identities = 29/67 (43%), Positives = 42/67 (62%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C K+PA+ + L+ + ++EAV AYGI TE C +L G LH YTLN +S + I
Sbjct: 229 CGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKARSTVQI 288
Query: 335 LKNLGLI 315
++NLGL+
Sbjct: 289 VRNLGLL 295
[88][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 65.1 bits (157), Expect = 4e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 332
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 333 LKRLGMWTE 341
[89][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 65.1 bits (157), Expect = 4e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 303 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 362
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 363 LKRLGMWTE 371
[90][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 56.2 bits (134), Expect(2) = 4e-09
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 4/70 (5%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT----LHLYTLNLEK 351
FC +P+ +M L I+ ++EAVK G + EMC++IL+ G + H YTLNLE+
Sbjct: 218 FCGISVPSAVMDRLSNIRLDDEAVKQVGCKIVAEMCEQILSAGLEVDVDGFHFYTLNLER 277
Query: 350 SALAILKNLG 321
S IL +LG
Sbjct: 278 STTRILTSLG 287
Score = 28.5 bits (62), Expect(2) = 4e-09
Identities = 9/19 (47%), Positives = 14/19 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGF 515
+PGIMP+ +Y ++MT F
Sbjct: 200 IPGIMPVQSYSSLVKMTQF 218
[91][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 60.1 bits (144), Expect(2) = 5e-09
Identities = 31/73 (42%), Positives = 42/73 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ E+++ +G + T MC+K+L G LH YTLN + +L I
Sbjct: 245 CGAEIPRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKAGAPGLHFYTLNQVEPSLGI 304
Query: 335 LKNLGLIEETSIP 297
KNLGL E IP
Sbjct: 305 WKNLGLGEREKIP 317
Score = 24.6 bits (52), Expect(2) = 5e-09
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N+ +R +
Sbjct: 226 VPGIMPIVNFSSLVRFS 242
[92][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 64.7 bits (156), Expect = 5e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 335 LKNLGLIEE 309
LK LGL E
Sbjct: 335 LKRLGLWNE 343
[93][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 64.7 bits (156), Expect = 5e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 335 LKNLGLIEE 309
LK LGL E
Sbjct: 335 LKRLGLWNE 343
[94][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 55.5 bits (132), Expect(2) = 6e-09
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K +IP + + LEP+K ++ V+ G L EMC+K+LA G LH YT+NL ++ I
Sbjct: 229 KIRIPPDWLDKLEPVKADDAKVREIGTKLVAEMCRKLLASGQIHHLHFYTMNLAQATRLI 288
Query: 335 LKNLGLIEETSIPRTRP 285
L+ L L+ P +P
Sbjct: 289 LEELRLLPSEEAPLHKP 305
Score = 28.9 bits (63), Expect(2) = 6e-09
Identities = 11/23 (47%), Positives = 16/23 (69%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI+ Y F+R + + K R
Sbjct: 209 IPGIMPISTYDAFMRRSNWTKIR 231
[95][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 58.2 bits (139), Expect(2) = 6e-09
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH--GFKTLHLYTLNLEKSALA 339
K +P + ALEPIK+++E V+ G L +MC++IL G + LH YT+NLEK
Sbjct: 230 KIVVPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEKGTKM 289
Query: 338 ILKNLGLI 315
+L+ L L+
Sbjct: 290 LLEELNLV 297
Score = 26.2 bits (56), Expect(2) = 6e-09
Identities = 11/21 (52%), Positives = 12/21 (57%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
VPGI PI + GF R T K
Sbjct: 210 VPGIAPIQTWNGFQRATSLAK 230
[96][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 355
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 356 LKRLGMWTE 364
[97][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 373
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 374 LKRLGMWTE 382
[98][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 64.3 bits (155), Expect = 6e-09
Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 335 LKNLGL-IEETSIP 297
L+ LGL IE+ P
Sbjct: 337 LRQLGLWIEDPRRP 350
[99][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 64.3 bits (155), Expect = 6e-09
Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 336
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 335 LKNLGL-IEETSIP 297
L+ LGL IE+ P
Sbjct: 337 LRQLGLWIEDPRRP 350
[100][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 332
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 333 LKRLGMWTE 341
[101][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 63.9 bits (154), Expect = 8e-09
Identities = 30/69 (43%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 131 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 190
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 191 LKRLGIWNE 199
[102][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 63.9 bits (154), Expect = 8e-09
Identities = 30/69 (43%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 263 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 322
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 323 LKRLGIWNE 331
[103][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 62.8 bits (151), Expect(2) = 1e-08
Identities = 27/66 (40%), Positives = 44/66 (66%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
+IP + ALEP+KD++ V+ G L EMC+K++ +G LH YT+NLEK+ I++
Sbjct: 232 RIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKATKMIIEK 291
Query: 326 LGLIEE 309
+GL+ +
Sbjct: 292 MGLLNQ 297
Score = 20.8 bits (42), Expect(2) = 1e-08
Identities = 8/14 (57%), Positives = 10/14 (71%)
Frame = -1
Query: 568 PGIMPINNYKGFIR 527
PGIMPI ++ F R
Sbjct: 211 PGIMPIQSWSTFNR 224
[104][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 55.5 bits (132), Expect(2) = 1e-08
Identities = 27/70 (38%), Positives = 42/70 (60%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
KIP + A+LE +K+++ AV+ G L EMC++I+ G LH YT+NL ++ +L+
Sbjct: 231 KIPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEE 290
Query: 326 LGLIEETSIP 297
L L T P
Sbjct: 291 LNLTPSTQRP 300
Score = 28.1 bits (61), Expect(2) = 1e-08
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPIN Y F+R
Sbjct: 209 IPGIMPINTYASFLR 223
[105][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 58.5 bits (140), Expect(2) = 1e-08
Identities = 29/66 (43%), Positives = 42/66 (63%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + LE D+ ++++A+G + TEMC+K+LA G LH YTLN + +LAI
Sbjct: 216 CGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAI 275
Query: 335 LKNLGL 318
NLGL
Sbjct: 276 WNNLGL 281
Score = 25.0 bits (53), Expect(2) = 1e-08
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 197 VPGIMPITNYSKLARFS 213
[106][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 58.5 bits (140), Expect(2) = 1e-08
Identities = 32/90 (35%), Positives = 49/90 (54%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
+ KIP E + ALEP+K+++ AV+ G L MC+K+LA+G LH YT+NL ++ +L
Sbjct: 229 QAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
+ L P Q+K G +E
Sbjct: 289 EELQWAPSADRPLQHALPWKQSKGLGRREE 318
Score = 24.6 bits (52), Expect(2) = 1e-08
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+PGIMPI Y F+R ++ +
Sbjct: 209 LPGIMPIATYASFLRRANHMQAK 231
[107][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 56.2 bits (134), Expect(2) = 1e-08
Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG--FKTLHLYTLNLEKSAL 342
CKT++P ++ +E +K+N EA+K YG+ +M ++I A G + LH YTLN
Sbjct: 239 CKTRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNSSAQTF 298
Query: 341 AILKNLGLIEE 309
+LK L + E
Sbjct: 299 QVLKRLNALVE 309
Score = 26.9 bits (58), Expect(2) = 1e-08
Identities = 10/23 (43%), Positives = 13/23 (56%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQR 503
+ G++PI Y GF RM K R
Sbjct: 220 IAGLLPITTYAGFTRMVSLCKTR 242
[108][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 57.4 bits (137), Expect(2) = 1e-08
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IPA + ++PI+D+ EAVKA GI L + C+++L G LH YTLN ++ +AI
Sbjct: 184 CGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGVPGLHFYTLNKSEATIAI 243
Query: 335 LKNL 324
L
Sbjct: 244 RNQL 247
Score = 25.8 bits (55), Expect(2) = 1e-08
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI NY +R +
Sbjct: 165 IPGIMPIGNYDQIVRFS 181
[109][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/74 (43%), Positives = 47/74 (63%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 335 LKNLGL-IEETSIP 297
LK LGL IE+ P
Sbjct: 332 LKRLGLWIEDPRRP 345
[110][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 63.2 bits (152), Expect = 1e-08
Identities = 29/73 (39%), Positives = 46/73 (63%), Gaps = 1/73 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 342
+C ++P + L P+ D++E V+ G L +MC+++L G + LHLYT+NLE+ L
Sbjct: 220 WCGVRVPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPL 279
Query: 341 AILKNLGLIEETS 303
IL+ LGL+ E S
Sbjct: 280 VILERLGLLPEAS 292
[111][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/74 (43%), Positives = 47/74 (63%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 335 LKNLGL-IEETSIP 297
LK LGL IE+ P
Sbjct: 332 LKRLGLWIEDPRRP 345
[112][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 55.5 bits (132), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 41/66 (62%), Gaps = 2/66 (3%)
Frame = -3
Query: 509 TKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH--GFKTLHLYTLNLEKSALAI 336
T +P AL+P++D+++ V+ G L EMCKKI+ G LH+YT+NLEK + +
Sbjct: 247 TLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLEKGSRML 306
Query: 335 LKNLGL 318
L LGL
Sbjct: 307 LDYLGL 312
Score = 26.9 bits (58), Expect(2) = 2e-08
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI Y GF R T
Sbjct: 226 IPGVMPIQTYGGFQRAT 242
[113][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 54.3 bits (129), Expect(2) = 2e-08
Identities = 27/70 (38%), Positives = 41/70 (58%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
KIP + AALE +K+++ AV+ G L EMC++I+ G LH YT+NL ++ +L+
Sbjct: 231 KIPPKWSAALEEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEE 290
Query: 326 LGLIEETSIP 297
L L P
Sbjct: 291 LSLTPSNQRP 300
Score = 28.1 bits (61), Expect(2) = 2e-08
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPIN Y F+R
Sbjct: 209 IPGIMPINTYASFLR 223
[114][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 59.3 bits (142), Expect(2) = 2e-08
Identities = 30/72 (41%), Positives = 43/72 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++ +G + TEMC K+LA G LH YTLN + +L+I
Sbjct: 216 CGAEIPRWIRKQLEAYGDDSDSIRKFGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSLSI 275
Query: 335 LKNLGLIEETSI 300
KNLG+ E I
Sbjct: 276 WKNLGIGEREKI 287
Score = 23.1 bits (48), Expect(2) = 2e-08
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N+ R +
Sbjct: 197 VPGIMPIVNFSNLTRFS 213
[115][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 57.4 bits (137), Expect(2) = 2e-08
Identities = 27/67 (40%), Positives = 43/67 (64%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + ALE D+EE+++A+G+ L TE+C+ +L + LH YT+N + I
Sbjct: 213 CGAEIPRWLRKALENYGDDEESLRAFGVDLVTELCEVLLENEAPGLHFYTMNQTEPTAQI 272
Query: 335 LKNLGLI 315
++NLGLI
Sbjct: 273 VRNLGLI 279
Score = 25.0 bits (53), Expect(2) = 2e-08
Identities = 10/16 (62%), Positives = 11/16 (68%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PGIMPI NYK R +
Sbjct: 195 PGIMPIINYKNLTRFS 210
[116][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[117][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[118][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[119][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 272 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEV 331
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 332 LKQLGMWTE 340
[120][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 55.5 bits (132), Expect(2) = 2e-08
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP I LE D+ E+++A+G+ + TE+C+++L G LH YT+N + L +
Sbjct: 55 CGTEIPRWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEGGAPGLHFYTMNQSEPTLRL 114
Query: 335 LKNLGL 318
LGL
Sbjct: 115 CDRLGL 120
Score = 26.9 bits (58), Expect(2) = 2e-08
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI NY +R +
Sbjct: 36 IPGIMPITNYSSLVRFS 52
[121][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 53.1 bits (126), Expect(2) = 3e-08
Identities = 29/65 (44%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K +P I + L+PI ++ VK YG L T+M +I+ G +HL TLNLEKS I
Sbjct: 232 KCPVPDSITSDLQPISSDDATVKRYGAELATKMVSQIIESGLVPGVHLCTLNLEKSVRMI 291
Query: 335 LKNLG 321
L NLG
Sbjct: 292 LDNLG 296
Score = 28.9 bits (63), Expect(2) = 3e-08
Identities = 11/21 (52%), Positives = 13/21 (61%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PGIMPI NY F R+ K
Sbjct: 212 IPGIMPIQNYASFRRLVNLTK 232
[122][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 57.0 bits (136), Expect(2) = 3e-08
Identities = 28/61 (45%), Positives = 40/61 (65%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
KIP E M LEP+K+++ AV+ G L E+C+KILA G LH YT+NL ++ +L+
Sbjct: 231 KIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEE 290
Query: 326 L 324
L
Sbjct: 291 L 291
Score = 25.0 bits (53), Expect(2) = 3e-08
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI Y F+R
Sbjct: 209 IPGIMPIATYASFLR 223
[123][TOP]
>UniRef100_A1U549 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter aquaeolei
VT8 RepID=A1U549_MARAV
Length = 289
Score = 57.4 bits (137), Expect(2) = 3e-08
Identities = 28/72 (38%), Positives = 43/72 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++ +G + TEMC+K+L G LH YTLN + +L+I
Sbjct: 216 CGAEIPRWIRKQLEAYGDDTDSIRKFGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSI 275
Query: 335 LKNLGLIEETSI 300
KNLG+ + I
Sbjct: 276 WKNLGISDREKI 287
Score = 24.6 bits (52), Expect(2) = 3e-08
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N+ +R +
Sbjct: 197 VPGIMPIVNFSSLVRFS 213
[124][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 56.2 bits (134), Expect(2) = 4e-08
Identities = 27/70 (38%), Positives = 43/70 (61%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
K+P E MA LE +K+++ AV+ G L +MC+KIL+ G + LH YT+NL ++ +L+
Sbjct: 231 KVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAGIRHLHFYTMNLAQATRMVLEE 290
Query: 326 LGLIEETSIP 297
L + P
Sbjct: 291 LDWLPSPDRP 300
Score = 25.4 bits (54), Expect(2) = 4e-08
Identities = 10/15 (66%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
VPGIMPI Y F+R
Sbjct: 209 VPGIMPIATYASFLR 223
[125][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 278 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 337
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 338 LKQLGMWTE 346
[126][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 335 LKNLGLIEE 309
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[127][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/70 (41%), Positives = 50/70 (71%), Gaps = 1/70 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 330
K+P EI+ L+ K++ EA++A+GI T+MC+++ A G + +HLYTLN+EK ++IL+
Sbjct: 251 KVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILE 310
Query: 329 NLGLIEETSI 300
NL + +E +
Sbjct: 311 NLKISKEPEL 320
[128][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 56.6 bits (135), Expect(2) = 5e-08
Identities = 29/69 (42%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLNLEK+ I
Sbjct: 272 KIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKTVSFI 331
Query: 335 LKNLGLIEE 309
++ GLI +
Sbjct: 332 IERCGLIPD 340
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI++YK R T
Sbjct: 250 IPGLMPIHSYKILTRTT 266
[129][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 56.6 bits (135), Expect(2) = 5e-08
Identities = 29/69 (42%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLNLEK+ I
Sbjct: 245 KIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKTVSFI 304
Query: 335 LKNLGLIEE 309
++ GLI +
Sbjct: 305 IERCGLIPD 313
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI++YK R T
Sbjct: 223 IPGLMPIHSYKILTRTT 239
[130][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 56.6 bits (135), Expect(2) = 5e-08
Identities = 29/69 (42%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLNLEK+ I
Sbjct: 245 KIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKTVSFI 304
Query: 335 LKNLGLIEE 309
++ GLI +
Sbjct: 305 IERCGLIPD 313
Score = 24.6 bits (52), Expect(2) = 5e-08
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI++YK R T
Sbjct: 223 IPGLMPIHSYKILTRTT 239
[131][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 57.0 bits (136), Expect(2) = 5e-08
Identities = 26/76 (34%), Positives = 44/76 (57%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
+ IP ALEP+K+++ V+ G L +MC+K++A G LH YT+NL ++ +L
Sbjct: 229 RCNIPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQATRMVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L L+ + P +P
Sbjct: 289 EELDLLPDVEAPLEKP 304
Score = 24.3 bits (51), Expect(2) = 5e-08
Identities = 8/15 (53%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ + F+R
Sbjct: 209 IPGIMPIHTHAAFLR 223
[132][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 61.2 bits (147), Expect = 5e-08
Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P EI +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + +
Sbjct: 272 KLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEV 331
Query: 335 LKNLGL 318
LK LG+
Sbjct: 332 LKRLGM 337
[133][TOP]
>UniRef100_A4FAF8 Methylenetetrahydrofolate reductase n=1 Tax=Saccharopolyspora
erythraea NRRL 2338 RepID=A4FAF8_SACEN
Length = 294
Score = 61.2 bits (147), Expect = 5e-08
Identities = 25/63 (39%), Positives = 41/63 (65%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNL 324
+P ++ LEP+ D+ A +A G+ L TE+C++++A G LH YTLN K+ ++ NL
Sbjct: 228 VPPAVLERLEPLADDAAAFRAEGVVLATELCERLIAEGVPALHFYTLNRSKATREVVSNL 287
Query: 323 GLI 315
GL+
Sbjct: 288 GLL 290
[134][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 61.2 bits (147), Expect = 5e-08
Identities = 33/90 (36%), Positives = 49/90 (54%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
K KIP + ALEP+K+++ AV+ G L EMC+K+LA+G LH YT+NL ++ +L
Sbjct: 229 KAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVL 288
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDGENQE 243
+ L P Q+K G +E
Sbjct: 289 EELNWAPSAERPLQHALPWKQSKGLGRREE 318
[135][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 51.6 bits (122), Expect(2) = 8e-08
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LAHGFKTLHLYTLNLEKSALA 339
C T++PA I L PI +++ VK YG+ L +M +++ L G + H TLNLEKS
Sbjct: 230 CGTRVPACITEDLAPISHDDQLVKDYGVKLAVQMIRRLRLEGGIQGFHFCTLNLEKSVQR 289
Query: 338 ILKNLGLIEETSIPRTRPA 282
+L+ L +T PA
Sbjct: 290 VLETLRWAGDTPGTMEPPA 308
Score = 28.9 bits (63), Expect(2) = 8e-08
Identities = 10/17 (58%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI Y F+R+T
Sbjct: 211 IPGIMPIQTYASFVRLT 227
[136][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 58.2 bits (139), Expect(2) = 1e-07
Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 330
+IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK
Sbjct: 288 EIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILK 347
Query: 329 NLGL 318
+LGL
Sbjct: 348 SLGL 351
Score = 21.9 bits (45), Expect(2) = 1e-07
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGIMPI Y+ R+
Sbjct: 266 IPGIMPIMGYESIKRI 281
[137][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 58.2 bits (139), Expect(2) = 1e-07
Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 330
+IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK
Sbjct: 267 EIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILK 326
Query: 329 NLGL 318
+LGL
Sbjct: 327 SLGL 330
Score = 21.9 bits (45), Expect(2) = 1e-07
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGIMPI Y+ R+
Sbjct: 245 IPGIMPIMGYESIKRI 260
[138][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 56.6 bits (135), Expect(2) = 1e-07
Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH---GFKTLHLYTLNLEKSALAIL 333
+P+ AL P++ ++E V+ G L +MCK IL + G K LH+YTLNLEK A +L
Sbjct: 236 VPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLL 295
Query: 332 KNLG 321
+ LG
Sbjct: 296 RELG 299
Score = 23.5 bits (49), Expect(2) = 1e-07
Identities = 8/13 (61%), Positives = 11/13 (84%)
Frame = -1
Query: 571 VPGIMPINNYKGF 533
+PGIMPI N++ F
Sbjct: 213 IPGIMPIQNWEKF 225
[139][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 55.1 bits (131), Expect(2) = 1e-07
Identities = 26/66 (39%), Positives = 41/66 (62%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + LE D+ ++++A+G + TEMC+++L G LH Y++NL +LAI
Sbjct: 214 CGAEIPRWVRKQLEAYGDDADSIRAFGEQVITEMCERLLQGGAPGLHFYSMNLAGPSLAI 273
Query: 335 LKNLGL 318
NLGL
Sbjct: 274 WNNLGL 279
Score = 25.0 bits (53), Expect(2) = 1e-07
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[140][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +
Sbjct: 398 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 457
Query: 335 LKNLGL-IEETSIP 297
LK LG+ IE+ P
Sbjct: 458 LKRLGMWIEDPRRP 471
[141][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 336
K ++P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +
Sbjct: 314 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 373
Query: 335 LKNLGL-IEETSIP 297
LK LG+ IE+ P
Sbjct: 374 LKRLGMWIEDPRRP 387
[142][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 60.1 bits (144), Expect = 1e-07
Identities = 32/87 (36%), Positives = 49/87 (56%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNL 324
IP + + ALEP+K+++ AV+ G L MC+K+LA G LH YT+NL+++ +L L
Sbjct: 218 IPPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGEL 277
Query: 323 GLIEETSIPRTRPANAIQAKEDGENQE 243
LI P +P Q+ G +E
Sbjct: 278 ELIPSHKTPLQKPLPWRQSLGLGRREE 304
[143][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 55.1 bits (131), Expect(2) = 1e-07
Identities = 26/75 (34%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 342
+C+ +P+ L+ KD++ V+ G L +MC K++ G+ LH YT+NLEKS +
Sbjct: 213 WCQINVPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLEKSTI 272
Query: 341 AILKNLGLIEETSIP 297
+L+ L LI+ + P
Sbjct: 273 MVLEKLQLIDTHNQP 287
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/15 (60%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ Y F R
Sbjct: 195 IPGIMPISTYASFSR 209
[144][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 55.1 bits (131), Expect(2) = 1e-07
Identities = 25/66 (37%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP I LE D+ +A++ +G+ + TE+C+++L G LH YTLN ++ L +
Sbjct: 221 CGADIPRWIRKRLEAFGDDRKAIRTFGLEVVTELCRRLLEQGAPGLHFYTLNRAEACLEV 280
Query: 335 LKNLGL 318
K LGL
Sbjct: 281 WKALGL 286
Score = 24.6 bits (52), Expect(2) = 1e-07
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N+ +R +
Sbjct: 202 VPGIMPITNHSQLVRFS 218
[145][TOP]
>UniRef100_C1DIB8 Methylenetetrahydrofolate reductase n=1 Tax=Azotobacter vinelandii
DJ RepID=C1DIB8_AZOVD
Length = 281
Score = 54.7 bits (130), Expect(2) = 1e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P + LE D+ E+++A+G + T MC+K+L G LH YTLN + +LAI
Sbjct: 214 CGAELPRWVRKQLEAYGDDLESIQAFGEQVVTAMCEKLLEGGAPGLHFYTLNQAEPSLAI 273
Query: 335 LKNLGL 318
NLGL
Sbjct: 274 WNNLGL 279
Score = 25.0 bits (53), Expect(2) = 1e-07
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[146][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 57.4 bits (137), Expect(2) = 2e-07
Identities = 30/64 (46%), Positives = 43/64 (67%), Gaps = 1/64 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 330
+IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK
Sbjct: 339 EIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILK 398
Query: 329 NLGL 318
LGL
Sbjct: 399 ALGL 402
Score = 21.9 bits (45), Expect(2) = 2e-07
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGIMPI Y+ R+
Sbjct: 317 IPGIMPIMGYESIKRI 332
[147][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 57.4 bits (137), Expect(2) = 2e-07
Identities = 30/64 (46%), Positives = 43/64 (67%), Gaps = 1/64 (1%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 330
+IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK
Sbjct: 289 EIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILK 348
Query: 329 NLGL 318
LGL
Sbjct: 349 ALGL 352
Score = 21.9 bits (45), Expect(2) = 2e-07
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGIMPI Y+ R+
Sbjct: 267 IPGIMPIMGYESIKRI 282
[148][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 57.4 bits (137), Expect(2) = 2e-07
Identities = 28/63 (44%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 327
IP I+ +LEPIK++++AV+ +GI +C+ +L++G T +HL+TLN E S+ IL+
Sbjct: 287 IPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQ 346
Query: 326 LGL 318
LGL
Sbjct: 347 LGL 349
Score = 21.9 bits (45), Expect(2) = 2e-07
Identities = 7/16 (43%), Positives = 12/16 (75%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRM 524
+PGI+PI +Y+ R+
Sbjct: 264 IPGILPIQSYESIRRV 279
[149][TOP]
>UniRef100_C5BTQ6 Methylenetetrahydrofolate reductase n=1 Tax=Teredinibacter turnerae
T7901 RepID=C5BTQ6_TERTT
Length = 282
Score = 53.5 bits (127), Expect(2) = 2e-07
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I L DN+E+++A+ L TE+C +L +G LH YT+N + I
Sbjct: 215 CGAEIPRWIRKRLNDFGDNQESLQAFTTDLVTELCATLLENGAPGLHFYTMNQVEPTRTI 274
Query: 335 LKNLGLIE 312
L NLGL++
Sbjct: 275 LTNLGLVD 282
Score = 25.8 bits (55), Expect(2) = 2e-07
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI NY+ R +
Sbjct: 196 IPGIMPITNYQNIARFS 212
[150][TOP]
>UniRef100_C6P2D6 Methylenetetrahydrofolate reductase n=1 Tax=Sideroxydans
lithotrophicus ES-1 RepID=C6P2D6_9GAMM
Length = 280
Score = 58.2 bits (139), Expect(2) = 2e-07
Identities = 26/65 (40%), Positives = 43/65 (66%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + +E D+ E+V+A+G+ + T++C+K++A G +LH YTLN ++L I
Sbjct: 214 CGAEIPRWMRKTMEGYGDDSESVQAFGLDVVTQLCEKLIAGGAPSLHFYTLNQANASLEI 273
Query: 335 LKNLG 321
LK LG
Sbjct: 274 LKRLG 278
Score = 21.2 bits (43), Expect(2) = 2e-07
Identities = 8/17 (47%), Positives = 10/17 (58%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI + R +
Sbjct: 195 VPGIMPIGRFSQLARFS 211
[151][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 57.0 bits (136), Expect(2) = 2e-07
Identities = 32/90 (35%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-AHGFKTLHLYTLNLEKSALAI 336
K ++P I+ LEPIK+++EA++ YG+ L MC+++L + +H+YTLN E + +
Sbjct: 250 KLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTLNREVATTEL 309
Query: 335 LKNLGLIEETSIPRTRP----ANAIQAKED 258
L+ LGL R P AN + +ED
Sbjct: 310 LQQLGLWRPYQSHRLLPWKPSANLKRLQED 339
Score = 21.9 bits (45), Expect(2) = 2e-07
Identities = 7/21 (33%), Positives = 12/21 (57%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVK 509
+PG+MPI Y +++ K
Sbjct: 230 IPGVMPIQAYASLLQLVKLSK 250
[152][TOP]
>UniRef100_B6J3R7 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
CbuG_Q212 RepID=B6J3R7_COXB2
Length = 290
Score = 55.1 bits (131), Expect(2) = 4e-07
Identities = 24/64 (37%), Positives = 42/64 (65%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN + I
Sbjct: 214 CATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTI 273
Query: 335 LKNL 324
++NL
Sbjct: 274 IENL 277
Score = 23.1 bits (48), Expect(2) = 4e-07
Identities = 8/17 (47%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI+++ +R +
Sbjct: 195 VPGIMPISDFDKLVRFS 211
[153][TOP]
>UniRef100_A9N9C8 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=A9N9C8_COXBR
Length = 290
Score = 55.1 bits (131), Expect(2) = 4e-07
Identities = 24/64 (37%), Positives = 42/64 (65%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN + I
Sbjct: 214 CATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTI 273
Query: 335 LKNL 324
++NL
Sbjct: 274 IENL 277
Score = 23.1 bits (48), Expect(2) = 4e-07
Identities = 8/17 (47%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI+++ +R +
Sbjct: 195 VPGIMPISDFDKLVRFS 211
[154][TOP]
>UniRef100_B6J6H7 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=B6J6H7_COXB1
Length = 290
Score = 55.1 bits (131), Expect(2) = 4e-07
Identities = 24/64 (37%), Positives = 42/64 (65%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN + I
Sbjct: 214 CATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTI 273
Query: 335 LKNL 324
++NL
Sbjct: 274 IENL 277
Score = 23.1 bits (48), Expect(2) = 4e-07
Identities = 8/17 (47%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI+++ +R +
Sbjct: 195 VPGIMPISDFDKLVRFS 211
[155][TOP]
>UniRef100_Q2L158 Methylenetetrahydrofolate reductase n=1 Tax=Bordetella avium 197N
RepID=Q2L158_BORA1
Length = 280
Score = 53.5 bits (127), Expect(2) = 4e-07
Identities = 23/64 (35%), Positives = 40/64 (62%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P I L D++ +++A+G+ + T++C+ +L HG LH YTLN ++ L+I
Sbjct: 215 CGAELPRWIRLRLAEFGDDKASIRAFGVDVVTKLCQTLLDHGVPGLHFYTLNQSEATLSI 274
Query: 335 LKNL 324
KNL
Sbjct: 275 WKNL 278
Score = 24.6 bits (52), Expect(2) = 4e-07
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 196 VPGIMPITNYSQLSRFS 212
[156][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 54.3 bits (129), Expect(2) = 5e-07
Identities = 31/71 (43%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
KIP EI+A +E K ++E VK G+ + +E+ KKI G + H YTLNLEKS I
Sbjct: 245 KIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKISTPGHRGFHFYTLNLEKSVSFI 304
Query: 335 LKNLGLIEETS 303
L+ LI +S
Sbjct: 305 LERCNLIPPSS 315
Score = 23.5 bits (49), Expect(2) = 5e-07
Identities = 8/17 (47%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +Y R+T
Sbjct: 223 IPGLMPIQSYHTLTRVT 239
[157][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 53.5 bits (127), Expect(2) = 5e-07
Identities = 25/76 (32%), Positives = 43/76 (56%)
Frame = -3
Query: 512 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAIL 333
+ IP ALEPIK+++ V+ G L +MC++++ G LH YT+NL ++ +L
Sbjct: 229 RCNIPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEAGITHLHFYTMNLAQATRMVL 288
Query: 332 KNLGLIEETSIPRTRP 285
+ L L+ + P +P
Sbjct: 289 EELDLLPDPGSPLEKP 304
Score = 24.3 bits (51), Expect(2) = 5e-07
Identities = 8/15 (53%), Positives = 12/15 (80%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
+PGIMPI+ + F+R
Sbjct: 209 IPGIMPIHTHASFLR 223
[158][TOP]
>UniRef100_C7QA95 5,10-methylenetetrahydrofolate reductase n=1 Tax=Catenulispora
acidiphila DSM 44928 RepID=C7QA95_CATAD
Length = 315
Score = 52.8 bits (125), Expect(2) = 5e-07
Identities = 24/61 (39%), Positives = 39/61 (63%)
Frame = -3
Query: 500 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 321
PA++ +L ++ ++ AV+A G+ T MC+++LA G LH TLN+ + L I +NLG
Sbjct: 241 PADLERSLMAVEGDKAAVRAVGVDWTTRMCERLLAEGVPGLHFITLNMSTATLEIYRNLG 300
Query: 320 L 318
L
Sbjct: 301 L 301
Score = 25.0 bits (53), Expect(2) = 5e-07
Identities = 9/24 (37%), Positives = 14/24 (58%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTGFVKQRY 500
+PG+MP+ N R+TG Q +
Sbjct: 217 LPGVMPVTNVAQIKRITGLTGQAF 240
[159][TOP]
>UniRef100_Q0VL81 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax borkumensis
SK2 RepID=Q0VL81_ALCBS
Length = 275
Score = 56.6 bits (135), Expect(2) = 6e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +P + + L IKD++ AVKA+G + T +C+++LA G LH YT+N L I
Sbjct: 210 CGADVPRWLQSKLNDIKDDDAAVKAFGEEVVTRLCERLLAMGAPGLHFYTMNQAGPNLRI 269
Query: 335 LKNLGL 318
L NLG+
Sbjct: 270 LDNLGM 275
Score = 20.8 bits (42), Expect(2) = 6e-07
Identities = 8/16 (50%), Positives = 10/16 (62%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PGIMPI N +R +
Sbjct: 192 PGIMPILNVANLLRFS 207
[160][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 50.8 bits (120), Expect(2) = 8e-07
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG--FKTLHLYTLNLEKSAL 342
CKT +P+++ +E +K+N + +K YG+ +M + I A G + LH YTLN
Sbjct: 239 CKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRASGLDYHHLHFYTLNNSAQIF 298
Query: 341 AILKNLGLIEE 309
ILK L + E
Sbjct: 299 KILKRLNALVE 309
Score = 26.2 bits (56), Expect(2) = 8e-07
Identities = 9/19 (47%), Positives = 12/19 (63%)
Frame = -1
Query: 565 GIMPINNYKGFIRMTGFVK 509
G++PI Y GF+RM K
Sbjct: 222 GLLPITTYAGFVRMVSLCK 240
[161][TOP]
>UniRef100_Q476T6 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha
JMP134 RepID=Q476T6_RALEJ
Length = 276
Score = 51.2 bits (121), Expect(2) = 8e-07
Identities = 23/66 (34%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +++P + LE D+ E+++A+G+ + T +C+++LA G LH YTLN + AI
Sbjct: 211 CGSEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAGGVPGLHFYTLNAAGATKAI 270
Query: 335 LKNLGL 318
+ L L
Sbjct: 271 WQRLKL 276
Score = 25.8 bits (55), Expect(2) = 8e-07
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY +R +
Sbjct: 192 VPGIMPITNYSQLMRFS 208
[162][TOP]
>UniRef100_B4X3B0 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax sp. DG881
RepID=B4X3B0_9GAMM
Length = 275
Score = 56.2 bits (134), Expect(2) = 8e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +P + + L IKD++ AVKA+G + T +C+++LA G LH YT+N L I
Sbjct: 210 CGADVPRWLQSKLNDIKDDDVAVKAFGEEVVTRLCERLLAMGAPGLHFYTMNQAGPNLRI 269
Query: 335 LKNLGL 318
L NLG+
Sbjct: 270 LDNLGM 275
Score = 20.8 bits (42), Expect(2) = 8e-07
Identities = 8/16 (50%), Positives = 10/16 (62%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PGIMPI N +R +
Sbjct: 192 PGIMPILNVANLLRFS 207
[163][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 54.7 bits (130), Expect(2) = 1e-06
Identities = 31/73 (42%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
K+P +IMA +E +K ++EAVK GI + E+ KK+ G + LH YTLNLEK+ I
Sbjct: 245 KVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKKLPCPGPRGLHFYTLNLEKAVAFI 304
Query: 335 LKNLGLIEETSIP 297
++ LI +S P
Sbjct: 305 VERCSLIPASSEP 317
Score = 21.9 bits (45), Expect(2) = 1e-06
Identities = 8/17 (47%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +Y R T
Sbjct: 223 IPGLMPIQSYHILTRTT 239
[164][TOP]
>UniRef100_A9KD99 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
Dugway 5J108-111 RepID=A9KD99_COXBN
Length = 290
Score = 55.1 bits (131), Expect(2) = 1e-06
Identities = 24/64 (37%), Positives = 42/64 (65%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN + I
Sbjct: 214 CATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTI 273
Query: 335 LKNL 324
++NL
Sbjct: 274 IENL 277
Score = 21.6 bits (44), Expect(2) = 1e-06
Identities = 7/17 (41%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI+++ ++ +
Sbjct: 195 VPGIMPISDFDKLVQFS 211
[165][TOP]
>UniRef100_B7V417 Methylenetetrahydrofolate reductase n=5 Tax=Pseudomonas aeruginosa
RepID=B7V417_PSEA8
Length = 290
Score = 51.6 bits (122), Expect(2) = 1e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P I LE D+ +++A+G + +EMC+++L G LH YTLN +LAI
Sbjct: 223 CGAELPRWIRKQLEAYGDDSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAI 282
Query: 335 LKNLGL 318
KNL L
Sbjct: 283 WKNLQL 288
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 204 VPGIMPITNYSKLARFS 220
[166][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 52.0 bits (123), Expect(2) = 1e-06
Identities = 27/66 (40%), Positives = 36/66 (54%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP I LE D+ A++A+G + T +C+K+L G LH YT+N LAI
Sbjct: 218 CGADIPRWIRKRLEGFGDDSAAIRAFGEDVVTRLCEKLLEAGAPGLHFYTMNQAGPTLAI 277
Query: 335 LKNLGL 318
NLGL
Sbjct: 278 WNNLGL 283
Score = 24.6 bits (52), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 199 VPGIMPITNYTQLARFS 215
[167][TOP]
>UniRef100_A6UYP0 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas aeruginosa
PA7 RepID=A6UYP0_PSEA7
Length = 282
Score = 51.6 bits (122), Expect(2) = 1e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P I LE D+ +++A+G + +EMC+++L G LH YTLN +LAI
Sbjct: 215 CGAELPRWIRKQLEAYGDDSRSIQAFGEQVISEMCERLLQGGAPGLHFYTLNQADPSLAI 274
Query: 335 LKNLGL 318
KNL L
Sbjct: 275 WKNLQL 280
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 196 VPGIMPITNYSKLARFS 212
[168][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 50.8 bits (120), Expect(2) = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P + LE D++EA++A+G+ + T++C ++L G LH YTLN + AI
Sbjct: 211 CGAEVPRWVAKRLESFGDDKEAIRAFGLDVVTDLCTRLLEAGVPGLHFYTLNAAGATKAI 270
Query: 335 LKNLGL 318
+ L L
Sbjct: 271 WQRLKL 276
Score = 25.8 bits (55), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY +R +
Sbjct: 192 VPGIMPITNYSQLMRFS 208
[169][TOP]
>UniRef100_B2AGG4 Methylenetetrahydrofolate reductase n=1 Tax=Cupriavidus taiwanensis
RepID=B2AGG4_CUPTR
Length = 276
Score = 50.8 bits (120), Expect(2) = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P + LE D+ E+++A+G+ + T +C+++LA G LH YTLN + AI
Sbjct: 211 CGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAAGVPGLHFYTLNAAGATKAI 270
Query: 335 LKNLGL 318
+ L L
Sbjct: 271 WQRLKL 276
Score = 25.8 bits (55), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY +R +
Sbjct: 192 VPGIMPITNYSQLMRFS 208
[170][TOP]
>UniRef100_Q84CU6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=uncultured
bacterium RepID=Q84CU6_9BACT
Length = 253
Score = 50.4 bits (119), Expect(2) = 1e-06
Identities = 26/74 (35%), Positives = 42/74 (56%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + LE D+ +++A GI + +E+C+ +LA G +LH YTLN I
Sbjct: 179 CGAEIPRWLRLRLEAYADDMPSLRALGIDVVSELCEVLLAGGVPSLHFYTLNQAGIISTI 238
Query: 335 LKNLGLIEETSIPR 294
+ N+GL + T+ R
Sbjct: 239 INNVGLEDATTQKR 252
Score = 26.2 bits (56), Expect(2) = 1e-06
Identities = 11/18 (61%), Positives = 12/18 (66%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMTG 518
VPGIMPI NY R +G
Sbjct: 160 VPGIMPIYNYTQLARFSG 177
[171][TOP]
>UniRef100_Q48PB6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. phaseolicola 1448A RepID=Q48PB6_PSE14
Length = 291
Score = 51.2 bits (121), Expect(2) = 1e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++A+G + T+MC+++L G LH YTLN + +LA+
Sbjct: 224 CGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGTPGLHFYTLNQAEPSLAV 283
Query: 335 LKNLGL 318
NL L
Sbjct: 284 WNNLQL 289
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 205 VPGIMPITNYSKLARFS 221
[172][TOP]
>UniRef100_UPI0001AF5FB3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. oryzae str. 1_6 RepID=UPI0001AF5FB3
Length = 281
Score = 51.2 bits (121), Expect(2) = 1e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++A+G + T+MC+++L G LH YTLN + +LA+
Sbjct: 214 CGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAV 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLQL 279
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[173][TOP]
>UniRef100_UPI0001873BC3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. tomato T1 RepID=UPI0001873BC3
Length = 281
Score = 51.2 bits (121), Expect(2) = 1e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++A+G + T+MC+++L G LH YTLN + +LA+
Sbjct: 214 CGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEDGAPGLHFYTLNQAEPSLAV 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLQL 279
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[174][TOP]
>UniRef100_Q4ZZ93 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. syringae B728a RepID=Q4ZZ93_PSEU2
Length = 281
Score = 51.2 bits (121), Expect(2) = 1e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++A+G + T+MC+++L G LH YTLN + +LA+
Sbjct: 214 CGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAV 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLQL 279
Score = 25.0 bits (53), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[175][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 55.1 bits (131), Expect(2) = 1e-06
Identities = 24/66 (36%), Positives = 41/66 (62%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D++++++A+GI + T++C+ +L G +H YT+N + L I
Sbjct: 213 CGAEIPRWISKRLEGFADDQDSIRAFGIDVVTQLCQTLLESGAPGIHFYTMNQTQPTLQI 272
Query: 335 LKNLGL 318
+NLGL
Sbjct: 273 CRNLGL 278
Score = 21.2 bits (43), Expect(2) = 1e-06
Identities = 8/15 (53%), Positives = 9/15 (60%)
Frame = -1
Query: 565 GIMPINNYKGFIRMT 521
GIMPI NY R +
Sbjct: 196 GIMPITNYANLARFS 210
[176][TOP]
>UniRef100_Q8Y389 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=Q8Y389_RALSO
Length = 276
Score = 53.9 bits (128), Expect(2) = 1e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN + AI
Sbjct: 211 CGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAAATRAI 270
Query: 335 LKNLGL 318
+ LGL
Sbjct: 271 WQRLGL 276
Score = 22.3 bits (46), Expect(2) = 1e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 192 VPGIMPITNSSQLMRFS 208
[177][TOP]
>UniRef100_B5S7H8 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=B5S7H8_RALSO
Length = 276
Score = 53.9 bits (128), Expect(2) = 1e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN + AI
Sbjct: 211 CGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAAATRAI 270
Query: 335 LKNLGL 318
+ LGL
Sbjct: 271 WQRLGL 276
Score = 22.3 bits (46), Expect(2) = 1e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 192 VPGIMPITNSSQLMRFS 208
[178][TOP]
>UniRef100_Q0KF23 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha H16
RepID=Q0KF23_RALEH
Length = 276
Score = 50.8 bits (120), Expect(2) = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P + LE D+ E+++A+G+ + T +C+++LA G LH YTLN + AI
Sbjct: 211 CGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAAGVPGLHFYTLNAAGATKAI 270
Query: 335 LKNLGL 318
+ L L
Sbjct: 271 WQRLKL 276
Score = 25.4 bits (54), Expect(2) = 1e-06
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY +R +
Sbjct: 192 VPGIMPITNYTQLMRFS 208
[179][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 56.2 bits (134), Expect = 2e-06
Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = -3
Query: 518 FCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSAL 342
+C IP E L+PIKD+++ V+ G L +C+K+L G+ + LH+YT+NLEK+
Sbjct: 231 WCDVHIPQEYFDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGYVSHLHIYTMNLEKAPQ 290
Query: 341 AILKNLGLIEETSIP 297
IL + L+ P
Sbjct: 291 MILDRMELLPSHDEP 305
[180][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 50.4 bits (119), Expect(2) = 2e-06
Identities = 25/69 (36%), Positives = 43/69 (62%), Gaps = 3/69 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
++P I++ LE ++ +++AVK G+ + T + +KI GF+ H YTLNLEK+ I
Sbjct: 245 QVPPHILSKLEAVRHDDDAVKRIGVDVITNLVDGIRKIPNPGFRGFHFYTLNLEKTVSFI 304
Query: 335 LKNLGLIEE 309
++ GLI +
Sbjct: 305 IERCGLIPD 313
Score = 25.4 bits (54), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI++YK R+T
Sbjct: 223 IPGLMPIHSYKILTRVT 239
[181][TOP]
>UniRef100_Q87V72 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. tomato RepID=Q87V72_PSESM
Length = 281
Score = 50.8 bits (120), Expect(2) = 2e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++A+G + T+MC+++L G LH YTLN + +LA+
Sbjct: 214 CGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAV 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLQL 279
Score = 25.0 bits (53), Expect(2) = 2e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[182][TOP]
>UniRef100_B1J2Y7 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida W619
RepID=B1J2Y7_PSEPW
Length = 281
Score = 50.8 bits (120), Expect(2) = 2e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + T MC+++L G LH YTLN +++LAI
Sbjct: 214 CGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEASLAI 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLKL 279
Score = 25.0 bits (53), Expect(2) = 2e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[183][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 53.5 bits (127), Expect(2) = 2e-06
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN + AI
Sbjct: 211 CGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAGATRAI 270
Query: 335 LKNLGL 318
+ LGL
Sbjct: 271 WQRLGL 276
Score = 22.3 bits (46), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 192 VPGIMPITNSSQLMRFS 208
[184][TOP]
>UniRef100_A0Y9Q7 Methylenetetrahydrofolate reductase n=1 Tax=marine gamma
proteobacterium HTCC2143 RepID=A0Y9Q7_9GAMM
Length = 276
Score = 52.0 bits (123), Expect(2) = 2e-06
Identities = 24/66 (36%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE ++ E+V+ +GI + T++C+++LA G +H YT+N + I
Sbjct: 211 CGAEIPRWICQRLESFGNDSESVQEFGIEVVTQLCQRLLAEGAPGIHFYTMNQVEPNRQI 270
Query: 335 LKNLGL 318
KNLG+
Sbjct: 271 WKNLGI 276
Score = 23.9 bits (50), Expect(2) = 2e-06
Identities = 9/16 (56%), Positives = 10/16 (62%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PGIMPI NY R +
Sbjct: 193 PGIMPITNYHNLARFS 208
[185][TOP]
>UniRef100_UPI0001744B6A 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B6A
Length = 314
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 37/62 (59%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
++PA ++ AL ++ + AV G+H TE C ++L HG +HLYTLN L ILK
Sbjct: 235 RVPARLLKALMKVQHDPAAVLEVGLHHATEQCSELLHHGVSGIHLYTLNQAGPILEILKR 294
Query: 326 LG 321
LG
Sbjct: 295 LG 296
[186][TOP]
>UniRef100_B5HCL5 Methylenetetrahydrofolate reductase n=1 Tax=Streptomyces
pristinaespiralis ATCC 25486 RepID=B5HCL5_STRPR
Length = 305
Score = 55.8 bits (133), Expect = 2e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = -3
Query: 500 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 321
PAE+ + +KD+ AV++ GI TE C ++LA G LH TLN + L I +NLG
Sbjct: 241 PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG 300
Query: 320 LIEET 306
L E++
Sbjct: 301 LHEQS 305
[187][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 55.8 bits (133), Expect = 2e-06
Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
Frame = -3
Query: 545 LQGIYPHDWFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLY 369
+ GI P + ++P IM L+ IKDN+ A++ YG+ MC+++L G LH Y
Sbjct: 206 IPGILPIQ-LSRLEVPKSIMDDLQTIKDNDVAIRNYGVQKAINMCRELLDSGLVPGLHFY 264
Query: 368 TLNLEKSALAILKNLGL-IEETSIPRTRPANAIQAKEDGENQERPTEDM 225
TLN E + IL LGL + + R P A NQ+R TED+
Sbjct: 265 TLNREVATREILTALGLWCMDPAASRPLPWRA------SANQKRFTEDV 307
[188][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 50.4 bits (119), Expect(2) = 2e-06
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA---HGFKTLHLYTLNLEKSALAIL 333
IP IM+ +E ++ ++E VK G+ + +E+ +I A G + H YTLNLEKS IL
Sbjct: 246 IPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKALPNPGQRGYHFYTLNLEKSVTLIL 305
Query: 332 KNLGLIEETSIPRTRPANAIQAKEDG 255
++ LI P N A EDG
Sbjct: 306 ESCDLIP--------PCNDDSAVEDG 323
Score = 25.0 bits (53), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI+ YK R+T
Sbjct: 223 IPGLMPIHGYKILTRVT 239
[189][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 51.6 bits (122), Expect(2) = 2e-06
Identities = 30/72 (41%), Positives = 43/72 (59%), Gaps = 3/72 (4%)
Frame = -3
Query: 503 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAIL 333
+P EI+A +E K ++EAVK G+ + +E+ K I G + LH +TLNLEKS IL
Sbjct: 246 VPPEILARIEKCKMDDEAVKRVGVDVVSELVDEIKTISCPGPRGLHFFTLNLEKSVSFIL 305
Query: 332 KNLGLIEETSIP 297
+ LI +S P
Sbjct: 306 ERCNLIPSSSEP 317
Score = 23.9 bits (50), Expect(2) = 2e-06
Identities = 8/17 (47%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +Y R+T
Sbjct: 223 IPGLMPIQSYSRLTRIT 239
[190][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 50.1 bits (118), Expect(2) = 2e-06
Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
KIP I+A L+ +K +++AVK G+ + E+ KK+ G + H YTLNLEK+ I
Sbjct: 245 KIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKLPTPGLRGFHFYTLNLEKTVSFI 304
Query: 335 LKNLGLIEE 309
L+ LI +
Sbjct: 305 LERCKLIPD 313
Score = 25.4 bits (54), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI++YK R+T
Sbjct: 223 IPGLMPIHSYKILTRVT 239
[191][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 49.3 bits (116), Expect(2) = 2e-06
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG--FKTLHLYTLNLEKSAL 342
CKT +P+++ +E +K+N + +K YG+ +M + I G + LH YTLN
Sbjct: 239 CKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGLDYHHLHFYTLNNSAQTF 298
Query: 341 AILKNLGLIEE 309
+LK L + E
Sbjct: 299 KVLKRLNALVE 309
Score = 26.2 bits (56), Expect(2) = 2e-06
Identities = 9/19 (47%), Positives = 12/19 (63%)
Frame = -1
Query: 565 GIMPINNYKGFIRMTGFVK 509
G++PI Y GF+RM K
Sbjct: 222 GLLPITTYAGFVRMVSLCK 240
[192][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 49.7 bits (117), Expect(2) = 2e-06
Identities = 23/71 (32%), Positives = 41/71 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + LE D+ +++ +G + T +C+++LA G +H YTLN + +LA+
Sbjct: 216 CGAEIPRWVRKQLEAYGDDSASIRKFGEEVVTRLCERLLAAGAPGIHFYTLNQAEPSLAV 275
Query: 335 LKNLGLIEETS 303
NL L ++ S
Sbjct: 276 WDNLNLGDKIS 286
Score = 25.8 bits (55), Expect(2) = 2e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 197 VPGIMPITNYSNLARFS 213
[193][TOP]
>UniRef100_C7RKF7 5,10-methylenetetrahydrofolate reductase n=1 Tax=Candidatus
Accumulibacter phosphatis clade IIA str. UW-1
RepID=C7RKF7_9PROT
Length = 279
Score = 51.2 bits (121), Expect(2) = 2e-06
Identities = 24/66 (36%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G+ + T++C+K+LA G LH YTLN +
Sbjct: 213 CGAEIPRWIRKKLESYGDDSASIRAFGLDVVTQLCEKLLASGAPGLHFYTLNQASLTSTL 272
Query: 335 LKNLGL 318
+ LGL
Sbjct: 273 WQRLGL 278
Score = 24.3 bits (51), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI++Y R +
Sbjct: 194 VPGIMPISSYSSLARFS 210
[194][TOP]
>UniRef100_B1Y645 Methylenetetrahydrofolate reductase n=1 Tax=Leptothrix cholodnii
SP-6 RepID=B1Y645_LEPCP
Length = 279
Score = 49.3 bits (116), Expect(2) = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 327
+IP I L+ D+ ++KA+G+ + T++C+++ A G LH YT+N + L I +
Sbjct: 217 EIPRWIRLRLQSYGDDSASIKAFGLDVVTDLCERLRAGGVPALHFYTMNSSAAVLQICER 276
Query: 326 LGL 318
LGL
Sbjct: 277 LGL 279
Score = 26.2 bits (56), Expect(2) = 2e-06
Identities = 11/15 (73%), Positives = 11/15 (73%)
Frame = -1
Query: 571 VPGIMPINNYKGFIR 527
VPGIMPI N G IR
Sbjct: 195 VPGIMPITNSSGIIR 209
[195][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 53.1 bits (126), Expect(2) = 2e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P I LE D+ E+++A+G+ + T MC ++L G LH YTLN S AI
Sbjct: 211 CGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGGAPGLHFYTLNAAGSTRAI 270
Query: 335 LKNLGL 318
+ LGL
Sbjct: 271 WQRLGL 276
Score = 22.3 bits (46), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 192 VPGIMPITNSSQLMRFS 208
[196][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 53.1 bits (126), Expect(2) = 2e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C ++P I LE D+ E+++A+G+ + T MC ++L G LH YTLN S AI
Sbjct: 211 CGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGGAPGLHFYTLNAAGSTRAI 270
Query: 335 LKNLGL 318
+ LGL
Sbjct: 271 WQRLGL 276
Score = 22.3 bits (46), Expect(2) = 2e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 192 VPGIMPITNSSQLMRFS 208
[197][TOP]
>UniRef100_A3TKC9 Methylenetetrahydrofolate reductase n=1 Tax=Janibacter sp. HTCC2649
RepID=A3TKC9_9MICO
Length = 295
Score = 50.4 bits (119), Expect(2) = 3e-06
Identities = 21/64 (32%), Positives = 40/64 (62%)
Frame = -3
Query: 509 TKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILK 330
T +PA ++ L+ + ++ AV++ G+ + TE+ +++LA G LH T+N + L + +
Sbjct: 227 TPLPAAVVDRLQAVSEDPAAVRSVGVEIATEIAQRMLAEGAPGLHFITMNRSTATLEVYE 286
Query: 329 NLGL 318
NLGL
Sbjct: 287 NLGL 290
Score = 24.6 bits (52), Expect(2) = 3e-06
Identities = 9/16 (56%), Positives = 11/16 (68%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PG+MP+ N K RMT
Sbjct: 207 PGLMPVTNLKQITRMT 222
[198][TOP]
>UniRef100_Q88D51 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida
KT2440 RepID=Q88D51_PSEPK
Length = 295
Score = 50.1 bits (118), Expect(2) = 3e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + T MC+++L G LH YTLN + +LAI
Sbjct: 228 CGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAI 287
Query: 335 LKNLGL 318
NL L
Sbjct: 288 WNNLKL 293
Score = 25.0 bits (53), Expect(2) = 3e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 209 VPGIMPITNYSKLARFS 225
[199][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 53.1 bits (126), Expect(2) = 3e-06
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP E++ E DN E K GI T C ++ HG K LH YTLN + + I
Sbjct: 224 CGATIPEEVVQKFEKYADNPEETKKIGIEFATLQCMDLIKHGVKGLHFYTLNKSDATIKI 283
Query: 335 LKNL 324
+N+
Sbjct: 284 YENI 287
Score = 21.9 bits (45), Expect(2) = 3e-06
Identities = 7/10 (70%), Positives = 9/10 (90%)
Frame = -1
Query: 571 VPGIMPINNY 542
+PGIMPI N+
Sbjct: 205 IPGIMPITNF 214
[200][TOP]
>UniRef100_C7HXI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Thiomonas
intermedia K12 RepID=C7HXI3_THIIN
Length = 285
Score = 52.4 bits (124), Expect(2) = 3e-06
Identities = 23/65 (35%), Positives = 41/65 (63%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I L+ D+ E+++A+G + + +C++++A G LH YTLN ++ LA+
Sbjct: 220 CGAEIPRWIRLRLQSYGDDRESIRAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAV 279
Query: 335 LKNLG 321
L +LG
Sbjct: 280 LDDLG 284
Score = 22.7 bits (47), Expect(2) = 3e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI N +R +
Sbjct: 201 VPGIMPITNSSQLLRFS 217
[201][TOP]
>UniRef100_Q1R0K0 Methylenetetrahydrofolate reductase n=1 Tax=Chromohalobacter
salexigens DSM 3043 RepID=Q1R0K0_CHRSD
Length = 282
Score = 50.4 bits (119), Expect(2) = 3e-06
Identities = 25/64 (39%), Positives = 36/64 (56%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP I LE D+ E+++A+G + T +C+++L G LH YTLN AL +
Sbjct: 215 CGADIPRWIRKQLEAYGDDSESIQAFGSEVVTRLCQRLLDGGAPGLHFYTLNQATPALRV 274
Query: 335 LKNL 324
L NL
Sbjct: 275 LDNL 278
Score = 24.6 bits (52), Expect(2) = 3e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 196 VPGIMPITNYTKLARFS 212
[202][TOP]
>UniRef100_Q1I3W4 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas entomophila
L48 RepID=Q1I3W4_PSEE4
Length = 281
Score = 50.1 bits (118), Expect(2) = 3e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + T MC+++L G LH YTLN + +LAI
Sbjct: 214 CGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAI 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLKL 279
Score = 25.0 bits (53), Expect(2) = 3e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYNKLARFS 211
[203][TOP]
>UniRef100_B0KM01 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida GB-1
RepID=B0KM01_PSEPG
Length = 281
Score = 50.1 bits (118), Expect(2) = 3e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + T MC+++L G LH YTLN + +LAI
Sbjct: 214 CGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAI 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLKL 279
Score = 25.0 bits (53), Expect(2) = 3e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[204][TOP]
>UniRef100_A5WA10 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida F1
RepID=A5WA10_PSEP1
Length = 281
Score = 50.1 bits (118), Expect(2) = 3e-06
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + T MC+++L G LH YTLN + +LAI
Sbjct: 214 CGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAI 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLKL 279
Score = 25.0 bits (53), Expect(2) = 3e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[205][TOP]
>UniRef100_Q21NJ7 Methylenetetrahydrofolate reductase n=1 Tax=Saccharophagus
degradans 2-40 RepID=Q21NJ7_SACD2
Length = 297
Score = 50.8 bits (120), Expect(2) = 4e-06
Identities = 25/66 (37%), Positives = 37/66 (56%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP + +E DN+EA+ ++GI +E+C +L G LH YT+N + I
Sbjct: 214 CGADIPRWMRKRMESFGDNQEALISFGIDWISELCDTLLDAGAPGLHFYTMNQTEPTATI 273
Query: 335 LKNLGL 318
+KNLGL
Sbjct: 274 IKNLGL 279
Score = 23.9 bits (50), Expect(2) = 4e-06
Identities = 9/16 (56%), Positives = 11/16 (68%)
Frame = -1
Query: 568 PGIMPINNYKGFIRMT 521
PGIMPI NY+ R +
Sbjct: 196 PGIMPILNYRNLARFS 211
[206][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 52.0 bits (123), Expect(2) = 4e-06
Identities = 23/64 (35%), Positives = 37/64 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP +++ LE ++++ E V GI TE C+ +L +G K LH YTLN K+ + I
Sbjct: 225 CGATIPKDLVEKLEKVENSPEEVAKIGIDYATEQCEDLLKNGVKGLHFYTLNKSKATVEI 284
Query: 335 LKNL 324
+ +
Sbjct: 285 YRRI 288
Score = 22.7 bits (47), Expect(2) = 4e-06
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = -1
Query: 571 VPGIMPINNYK 539
+PGIMPI N++
Sbjct: 206 IPGIMPITNFR 216
[207][TOP]
>UniRef100_Q6J6A1 Methylenetetrahydrofolate reductase n=1 Tax=Collimonas fungivorans
RepID=Q6J6A1_9BURK
Length = 284
Score = 52.4 bits (124), Expect(2) = 4e-06
Identities = 24/66 (36%), Positives = 41/66 (62%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T+IP I L D+ ++++A+G+ + T++C+++LA G LH YTLN + +AI
Sbjct: 219 CGTEIPRWIRLKLASYGDDSDSIRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAI 278
Query: 335 LKNLGL 318
+ L L
Sbjct: 279 WQRLKL 284
Score = 22.3 bits (46), Expect(2) = 4e-06
Identities = 8/17 (47%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+ GIMPI NY +R +
Sbjct: 200 IAGIMPITNYSQLMRFS 216
[208][TOP]
>UniRef100_Q3K5D6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas fluorescens
Pf0-1 RepID=Q3K5D6_PSEPF
Length = 281
Score = 49.7 bits (117), Expect(2) = 4e-06
Identities = 24/66 (36%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ ++++ +G + TEMC+++L G LH Y++N + +LAI
Sbjct: 214 CGAEIPRWIRKQLEAYGDDSQSIQRFGEQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAI 273
Query: 335 LKNLGL 318
NL L
Sbjct: 274 WNNLKL 279
Score = 25.0 bits (53), Expect(2) = 4e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 195 VPGIMPITNYSKLARFS 211
[209][TOP]
>UniRef100_A4A9E4 Methylenetetrahydrofolate reductase n=1 Tax=Congregibacter
litoralis KT71 RepID=A4A9E4_9GAMM
Length = 278
Score = 53.5 bits (127), Expect(2) = 4e-06
Identities = 24/66 (36%), Positives = 40/66 (60%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D++E+++A+GI + T++C+ +L +H YT+N + L I
Sbjct: 213 CGAEIPRWISKRLEGFADDQESIRAFGIDVVTQLCQTLLESDAPGIHFYTMNQAQPTLQI 272
Query: 335 LKNLGL 318
+NLGL
Sbjct: 273 CRNLGL 278
Score = 21.2 bits (43), Expect(2) = 4e-06
Identities = 8/15 (53%), Positives = 9/15 (60%)
Frame = -1
Query: 565 GIMPINNYKGFIRMT 521
GIMPI NY R +
Sbjct: 196 GIMPITNYANLARFS 210
[210][TOP]
>UniRef100_C9YE70 5,10-methylenetetrahydrofolate reductase n=1 Tax=Curvibacter
putative symbiont of Hydra magnipapillata
RepID=C9YE70_9BURK
Length = 305
Score = 54.7 bits (130), Expect = 5e-06
Identities = 25/66 (37%), Positives = 39/66 (59%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I L+ D ++KA+G+ + T++C+++ A G LH YT+N LA+
Sbjct: 238 CGAEIPRWIRLRLQSYGDEVASIKAFGLEVVTDLCEQLRAGGAPALHFYTMNQSAPTLAL 297
Query: 335 LKNLGL 318
KNLGL
Sbjct: 298 CKNLGL 303
[211][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 48.9 bits (115), Expect(2) = 5e-06
Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF---KTLHLYTLNLEKSALAI 336
++PAE++A L+ +K ++E VK G+ + EM + I A + H YTLNLEK+ +
Sbjct: 248 RLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKARPETCRRGFHFYTLNLEKAVSHV 307
Query: 335 LKNLGLI------EETSIPRTRPANAIQAKEDG 255
+++ LI +E I T PA ++ +G
Sbjct: 308 VEDTHLIPTTIMDDEEIIVETTPAINLEPPPNG 340
Score = 25.4 bits (54), Expect(2) = 5e-06
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +YK +R T
Sbjct: 226 IPGLMPIQSYKILLRTT 242
[212][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 51.2 bits (121), Expect(2) = 5e-06
Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL------AHGFKTLHLYTLNLE 354
C +P+ +M L K ++EA+K G+ +M KKI+ HGF H TLNLE
Sbjct: 238 CGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGF---HFCTLNLE 294
Query: 353 KSALAILKNLGLI 315
+S ILKN GL+
Sbjct: 295 RSVALILKNSGLL 307
Score = 23.1 bits (48), Expect(2) = 5e-06
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+P IMPI +Y RMT
Sbjct: 219 IPAIMPIQSYGSLKRMT 235
[213][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 47.4 bits (111), Expect(2) = 6e-06
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH-GFKTLHLYTLNLEKSALA 339
C TK+P+ + A L PIK++++ VK YG+ + ++ G + H TLNLEKS
Sbjct: 227 CGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIHRLRNEGGIQGFHFCTLNLEKSVQR 286
Query: 338 ILKNL 324
+L+ L
Sbjct: 287 VLEEL 291
Score = 26.6 bits (57), Expect(2) = 6e-06
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PGIMPI Y F R+T
Sbjct: 208 IPGIMPIQTYATFARLT 224
[214][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 52.0 bits (123), Expect(2) = 7e-06
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP E++ E DN E K GI T C ++ HG K LH YTLN + + I
Sbjct: 224 CGATIPEEVVQKFEKYADNPEETKKIGIEFATLQCIDLIKHGAKGLHFYTLNKSDATIKI 283
Query: 335 LKNL 324
+N+
Sbjct: 284 YENI 287
Score = 21.9 bits (45), Expect(2) = 7e-06
Identities = 7/10 (70%), Positives = 9/10 (90%)
Frame = -1
Query: 571 VPGIMPINNY 542
+PGIMPI N+
Sbjct: 205 IPGIMPITNF 214
[215][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 52.0 bits (123), Expect(2) = 7e-06
Identities = 23/64 (35%), Positives = 33/64 (51%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C IP +++ E DN E K GI T+ C+ +L +G K LH YTLN + + I
Sbjct: 224 CGATIPEDVVKLFEKYADNPEETKKIGIEFATKQCEDLLKNGVKGLHFYTLNKSDATIKI 283
Query: 335 LKNL 324
N+
Sbjct: 284 YNNI 287
Score = 21.9 bits (45), Expect(2) = 7e-06
Identities = 7/10 (70%), Positives = 9/10 (90%)
Frame = -1
Query: 571 VPGIMPINNY 542
+PGIMPI N+
Sbjct: 205 IPGIMPITNF 214
[216][TOP]
>UniRef100_Q4K4H6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas fluorescens
Pf-5 RepID=Q4K4H6_PSEF5
Length = 288
Score = 48.9 bits (115), Expect(2) = 7e-06
Identities = 25/66 (37%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ +++A+G + ++MC+++L G LH YTLN +LAI
Sbjct: 221 CGAEIPRWIRKQLEAYGDDSASIQAFGEQVISDMCERLLQGGAPGLHFYTLNQADPSLAI 280
Query: 335 LKNLGL 318
NL L
Sbjct: 281 WNNLQL 286
Score = 25.0 bits (53), Expect(2) = 7e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 202 VPGIMPITNYSKLARFS 218
[217][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 50.1 bits (118), Expect(2) = 8e-06
Identities = 28/71 (39%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
++P E+++ +E K ++EAVK G+ + +E+ K I G + LH YTLNLEKS I
Sbjct: 245 RVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKSVSFI 304
Query: 335 LKNLGLIEETS 303
L+ LI +S
Sbjct: 305 LERCNLIPPSS 315
Score = 23.5 bits (49), Expect(2) = 8e-06
Identities = 8/17 (47%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +Y R+T
Sbjct: 223 IPGLMPIQSYPRLTRIT 239
[218][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 50.1 bits (118), Expect(2) = 8e-06
Identities = 28/71 (39%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Frame = -3
Query: 506 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLNLEKSALAI 336
++P E+++ +E K ++EAVK G+ + +E+ K I G + LH YTLNLEKS I
Sbjct: 245 RVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKSVSFI 304
Query: 335 LKNLGLIEETS 303
L+ LI +S
Sbjct: 305 LERCNLIPPSS 315
Score = 23.5 bits (49), Expect(2) = 8e-06
Identities = 8/17 (47%), Positives = 12/17 (70%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
+PG+MPI +Y R+T
Sbjct: 223 IPGLMPIQSYPRLTRIT 239
[219][TOP]
>UniRef100_B0T509 Methylenetetrahydrofolate reductase n=1 Tax=Caulobacter sp. K31
RepID=B0T509_CAUSK
Length = 320
Score = 43.5 bits (101), Expect(2) = 8e-06
Identities = 23/80 (28%), Positives = 37/80 (46%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C T +P + + + D+ + + + EMC K+ GF H YTLN AI
Sbjct: 239 CGTAVPDWLTKLFDGLDDDADTRRLIACSVAAEMCAKLQEQGFSDFHFYTLNRADLVYAI 298
Query: 335 LKNLGLIEETSIPRTRPANA 276
+ LG+ E ++P P +A
Sbjct: 299 CRVLGVRE--TVPAPSPISA 316
Score = 30.0 bits (66), Expect(2) = 8e-06
Identities = 9/17 (52%), Positives = 15/17 (88%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPG+MP+ N+KG ++M+
Sbjct: 220 VPGVMPVTNFKGLVKMS 236
[220][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 48.5 bits (114), Expect(2) = 8e-06
Identities = 24/66 (36%), Positives = 37/66 (56%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP I LE D+ E+++ +G + T+MC+ ++ + LH YTLN + I
Sbjct: 212 CGAEIPRWIRKQLEAYGDDVESIQKFGEEVVTQMCEDLVENDVPGLHFYTLNQADPCINI 271
Query: 335 LKNLGL 318
KNLGL
Sbjct: 272 WKNLGL 277
Score = 25.0 bits (53), Expect(2) = 8e-06
Identities = 10/17 (58%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI NY R +
Sbjct: 193 VPGIMPITNYSKLARFS 209
[221][TOP]
>UniRef100_A1K2Z6 Methylenetetrahydrofolate reductase n=1 Tax=Azoarcus sp. BH72
RepID=A1K2Z6_AZOSB
Length = 277
Score = 52.0 bits (123), Expect(2) = 8e-06
Identities = 24/66 (36%), Positives = 38/66 (57%)
Frame = -3
Query: 515 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 336
C +IP + E D+ +A++A+G+ + TE+C+K+LA G LH Y++N I
Sbjct: 211 CGAEIPRWMRRKFESYGDDADAIRAFGLDVVTELCEKLLAAGVPGLHFYSMNQSALTTEI 270
Query: 335 LKNLGL 318
K LGL
Sbjct: 271 CKRLGL 276
Score = 21.6 bits (44), Expect(2) = 8e-06
Identities = 8/17 (47%), Positives = 11/17 (64%)
Frame = -1
Query: 571 VPGIMPINNYKGFIRMT 521
VPGIMPI ++ R +
Sbjct: 192 VPGIMPIGSFSKLARFS 208