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[1][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 179 bits (455), Expect = 1e-43
Identities = 89/109 (81%), Positives = 95/109 (87%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAH
Sbjct: 232 VPGIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAH 291
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRT----RPANAIQAKED 261
G KTLHLYTLN+EKSALAIL NLGLIEE+ I R P N +AKED
Sbjct: 292 GIKTLHLYTLNMEKSALAILMNLGLIEESKITRALPWRPPTNVFRAKED 340
[2][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 178 bits (452), Expect = 2e-43
Identities = 86/109 (78%), Positives = 97/109 (88%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNY+GF+RMTGFCKTKIP E+MAALEPIKDNEEAVKAYGIHLGTEMCKK+LAH
Sbjct: 218 VPGIMPINNYRGFLRMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G K+LHLYTLN+EKSALAIL NLG+I+E+ S+P RPAN + KED
Sbjct: 278 GVKSLHLYTLNMEKSALAILMNLGMIDESKISRSLPWRRPANVFRTKED 326
[3][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 178 bits (451), Expect = 3e-43
Identities = 87/109 (79%), Positives = 95/109 (87%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKED 261
G KT+HLYTLN+EKSALAIL NLGLIEE+ I P RP N + KED
Sbjct: 278 GIKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
[4][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 178 bits (451), Expect = 3e-43
Identities = 87/109 (79%), Positives = 95/109 (87%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKED 261
G KT+HLYTLN+EKSALAIL NLGLIEE+ I P RP N + KED
Sbjct: 278 GIKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 176 bits (447), Expect = 9e-43
Identities = 88/109 (80%), Positives = 93/109 (85%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGFIRM GFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAH
Sbjct: 229 VPGIMPINNYKGFIRMAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAH 288
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKED 261
G KTLHLYTLN+EKSALAIL NLGLIEE+ I P P N + KED
Sbjct: 289 GIKTLHLYTLNMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKED 337
[6][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 175 bits (444), Expect = 2e-42
Identities = 87/109 (79%), Positives = 94/109 (86%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIPAEI AAL+PIKDNEEAVKAYGIHLGTEMCKKILA
Sbjct: 206 VPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILAS 265
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRT----RPANAIQAKED 261
G KTLHLYTLN+EK+ALAIL NLGLIEE+ + RT P N + KED
Sbjct: 266 GIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTLPWRPPTNVFRVKED 314
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 174 bits (442), Expect = 3e-42
Identities = 88/109 (80%), Positives = 93/109 (85%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAT 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G KTLHLYTLN+EKSAL IL NLGLIEE+ S+P P N + KED
Sbjct: 278 GIKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
[8][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 174 bits (442), Expect = 3e-42
Identities = 86/108 (79%), Positives = 93/108 (86%), Gaps = 4/108 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKI+AH
Sbjct: 233 VPGIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAH 292
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKE 264
G KTLHLYTLN+EKSALAIL NLGLIEE+ I P P N + KE
Sbjct: 293 GIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRPPTNVFRVKE 340
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 174 bits (442), Expect = 3e-42
Identities = 88/109 (80%), Positives = 93/109 (85%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAT 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G KTLHLYTLN+EKSAL IL NLGLIEE+ S+P P N + KED
Sbjct: 278 GIKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
[10][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 173 bits (439), Expect = 7e-42
Identities = 86/101 (85%), Positives = 90/101 (89%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGFIRMTGFCKTKIPA+IMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH
Sbjct: 219 VPGIMPINNYKGFIRMTGFCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 278
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQ 273
G TLHLYTLN+EKSALAIL NLGLIEET +A+Q
Sbjct: 279 GINTLHLYTLNMEKSALAILMNLGLIEETKFLGPYLGDALQ 319
[11][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 170 bits (431), Expect = 6e-41
Identities = 85/109 (77%), Positives = 92/109 (84%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGFIRM GFCKTKIP+EI AALEPIKDNEEAV+AYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPINNYKGFIRMAGFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP----ANAIQAKED 261
G KTLHLYTLN+EKSAL IL NLGLI+ T I R P N ++ KE+
Sbjct: 278 GIKTLHLYTLNMEKSALGILANLGLIDMTKIRRPLPWRPATNVLRTKEN 326
[12][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 167 bits (423), Expect = 5e-40
Identities = 82/109 (75%), Positives = 91/109 (83%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIP+EI AAL+PIKDNEEAVK YGIHLGTEMCKKILA
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILAT 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP----ANAIQAKED 261
G KTLHLYTLN++KSA+ IL NLGLIEE+ + R P N + KED
Sbjct: 278 GIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
[13][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 166 bits (420), Expect = 1e-39
Identities = 81/109 (74%), Positives = 91/109 (83%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIP+EI AAL+PIKDNEEAV+ YGIHLGTEMCKKILA
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILAT 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP----ANAIQAKED 261
G KTLHLYTLN++KSA+ IL NLGLIEE+ + R P N + KED
Sbjct: 278 GIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 166 bits (419), Expect = 2e-39
Identities = 80/109 (73%), Positives = 92/109 (84%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAH
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G +LHLYTLN++KSA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 278 GITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[15][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 166 bits (419), Expect = 2e-39
Identities = 80/109 (73%), Positives = 92/109 (84%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAH
Sbjct: 28 VPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH 87
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G +LHLYTLN++KSA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 88 GITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 136
[16][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 166 bits (419), Expect = 2e-39
Identities = 80/109 (73%), Positives = 92/109 (84%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAH
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G +LHLYTLN++KSA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 278 GITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[17][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 166 bits (419), Expect = 2e-39
Identities = 80/109 (73%), Positives = 92/109 (84%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+NYKGF+RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAH
Sbjct: 218 VPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET----SIPRTRPANAIQAKED 261
G +LHLYTLN++KSA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 278 GITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[18][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 158 bits (400), Expect = 2e-37
Identities = 78/109 (71%), Positives = 89/109 (81%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NYKGF+RMT CKTK+PAEIMAALEPIKDN+EAV+AYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPIQNYKGFLRMTTLCKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIE----ETSIPRTRPANAIQAKED 261
+TLHLY+LNLEKS L IL+NLGLI+ +P P N+ + KED
Sbjct: 278 DIRTLHLYSLNLEKSVLGILQNLGLIDFSRVSRPLPWRPPTNSKRTKED 326
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 158 bits (399), Expect = 3e-37
Identities = 77/109 (70%), Positives = 89/109 (81%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NYKGF+RMT CKTK+PAEIMA LEPIKDN+EAV+AYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPIQNYKGFLRMTSLCKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKED 261
+TLHLY+LNLEKS L IL+NLGLI+ + + P P N+ + KED
Sbjct: 278 DIRTLHLYSLNLEKSVLGILQNLGLIDFSKVTRPLPWRPPTNSKRTKED 326
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 144 bits (364), Expect = 4e-33
Identities = 76/109 (69%), Positives = 85/109 (77%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPINNYKGF+RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAH
Sbjct: 218 VPGIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAH 277
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI----PRTRPANAIQAKED 261
G KT L T++L +NLGLIEE+ I P RP N + KED
Sbjct: 278 GIKTFGL-TMDLP------WQNLGLIEESKISRPFPWRRPTNVFRVKED 319
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 125 bits (315), Expect = 2e-27
Identities = 63/103 (61%), Positives = 78/103 (75%), Gaps = 1/103 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y GF RMTGFCKTK+PAEI ALE IKDN+EAVKAYGI LG MC+++LA
Sbjct: 212 LPGIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLAS 271
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQA 270
G +H+YTLNLEKSA+AIL+ LGL++ + + R P + A
Sbjct: 272 GEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPA 314
[22][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 102 bits (254), Expect = 2e-20
Identities = 49/86 (56%), Positives = 60/86 (69%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y GF+RMT KTK+P IM LEPIKDN+E VK YG+ L EM K++L
Sbjct: 211 IPGIMPIQTYAGFVRMTTLSKTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDF 270
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLI 318
G + LH YTLNLE+S +LK L L+
Sbjct: 271 GVEGLHFYTLNLERSVRKVLKGLQLV 296
[23][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 93.2 bits (230), Expect = 1e-17
Identities = 44/85 (51%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPG+M IN Y GF++M FCKT++P + A +E IKD+ AVKA+G+ G EMC+ +LA
Sbjct: 292 VPGLMCINAYAGFVKMAKFCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLAS 351
Query: 395 G-FKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNLEK +L LG
Sbjct: 352 GHVSVLHFYTLNLEKVVYGVLDALG 376
[24][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 92.8 bits (229), Expect = 2e-17
Identities = 40/89 (44%), Positives = 62/89 (69%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + +C+ +P MA L+P+KD+++AV+ G L +MC+K+L
Sbjct: 212 IPGIMPITTYAAFLRRSSWCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDS 271
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEE 312
G+ T LH+YT+NLEK+ + +L LGL+ E
Sbjct: 272 GYVTHLHMYTMNLEKACIMVLDRLGLLSE 300
[25][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 92.0 bits (227), Expect = 3e-17
Identities = 47/110 (42%), Positives = 67/110 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G L +MCKKILA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ IL LGLI P +P Q+ G +E
Sbjct: 269 GIYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
[26][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 92.0 bits (227), Expect = 3e-17
Identities = 47/110 (42%), Positives = 67/110 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G L +MCKKILA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ IL LGLI P +P Q+ G +E
Sbjct: 269 GIYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
[27][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 92.0 bits (227), Expect = 3e-17
Identities = 45/96 (46%), Positives = 61/96 (63%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR T + K KIP M ALEP+K+++ AVK G L +EMC+K+L +
Sbjct: 209 IPGIMPISTYAAFIRRTNWVKCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDN 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL +S +L+ L L T P +P
Sbjct: 269 GINHLHFYTMNLAQSTTMVLEELNLKPSTETPLQKP 304
[28][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 92.0 bits (227), Expect = 3e-17
Identities = 43/96 (44%), Positives = 62/96 (64%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G L +MC+++LA
Sbjct: 209 IPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G K LH YT+NL ++ A+L+ L LI P RP
Sbjct: 269 GIKHLHFYTMNLAQATQAVLEELKLIPSEETPLQRP 304
[29][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 91.3 bits (225), Expect = 5e-17
Identities = 44/96 (45%), Positives = 60/96 (62%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + K +IP E + ALEP+K+++ AVK G L EMC+K+LA
Sbjct: 209 IPGIMPISTYAAFIRRANWTKARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ ++L L LI P RP
Sbjct: 269 GLNHLHFYTMNLAQATQSVLDELKLIPSEETPLQRP 304
[30][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 90.5 bits (223), Expect = 8e-17
Identities = 43/59 (72%), Positives = 48/59 (81%)
Frame = -1
Query: 563 MPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK 387
MPINN KGF+ MTGFCKTK+ A ALEPIKDNE+AV YGIHLGTEMCKK+L +G K
Sbjct: 1 MPINNSKGFLGMTGFCKTKVTA----ALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK 55
[31][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 90.1 bits (222), Expect = 1e-16
Identities = 42/88 (47%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI +Y +R +C+ ++P E + LEP+KD+++AV+ G L +MC+KILA
Sbjct: 212 IPGIMPITSYAALLRRAKWCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILAS 271
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIE 315
G T LHLYT+NLE+++L IL+ L LI+
Sbjct: 272 GHVTHLHLYTMNLERASLMILERLQLID 299
[32][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 90.1 bits (222), Expect = 1e-16
Identities = 42/96 (43%), Positives = 61/96 (63%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G L +MC+++LA
Sbjct: 209 IPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ A+L+ L LI P RP
Sbjct: 269 GINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRP 304
[33][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 90.1 bits (222), Expect = 1e-16
Identities = 42/96 (43%), Positives = 61/96 (63%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + K +IP + + ALEP+K+++ AVK G L +MC+++LA
Sbjct: 209 IPGIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ A+L+ L LI P RP
Sbjct: 269 GINHLHFYTMNLAQATQAVLEELKLIPSEETPLQRP 304
[34][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 89.0 bits (219), Expect = 2e-16
Identities = 42/86 (48%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI + +++T K IP EI +EPIKDN+ A++ YGI L T+MC+ +L
Sbjct: 225 IPGIFPIQTNRSLVQLTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNS 284
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL 321
G LH+YTLNLE + + ILKNLGL
Sbjct: 285 GKVHGLHMYTLNLETATIQILKNLGL 310
[35][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/110 (40%), Positives = 66/110 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + K ++P M ALEP K+++ AVK G L +EMC+KIL
Sbjct: 209 LPGIMPISTYAAFLRRSNWVKCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G + LH YT+NL +S +L+ L LI + P +P Q+ G +E
Sbjct: 269 GIRHLHFYTMNLAQSTKMVLEELDLIPSSETPLQKPLPWRQSLGLGRREE 318
[36][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 88.6 bits (218), Expect = 3e-16
Identities = 39/92 (42%), Positives = 64/92 (69%), Gaps = 1/92 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI +Y FIR T +C+ +P + LEP+KD+++ V+ G L E+C+K+L
Sbjct: 214 IPGIMPITSYPSFIRRTQWCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDS 273
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEETSI 303
G+ LH+YT+NLEK++L IL+ L L++ +++
Sbjct: 274 GYVNHLHMYTMNLEKASLMILEKLDLLKRSNV 305
[37][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 88.6 bits (218), Expect = 3e-16
Identities = 42/96 (43%), Positives = 59/96 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y FIR + KT IP + + ALEP+K+++ AVK G L +MC++++A
Sbjct: 209 IPGIMPIQTYAAFIRRANWTKTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G K LH YT+NL +S +L+ L L P RP
Sbjct: 269 GIKHLHFYTMNLAQSTQLVLEELELTPTAEAPIPRP 304
[38][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 88.6 bits (218), Expect = 3e-16
Identities = 42/96 (43%), Positives = 60/96 (62%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y FIR + + K K+P+E M ALEP+K+++ AV+ G L MC++++A
Sbjct: 209 IPGIMPIQTYASFIRRSNWTKVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G K LH YT+NL ++ +LK L L P RP
Sbjct: 269 GIKHLHFYTMNLAQATQLVLKELELTPSEDSPIQRP 304
[39][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 88.6 bits (218), Expect = 3e-16
Identities = 41/91 (45%), Positives = 57/91 (62%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI + FIR + KIP M L P+KD++E V+ G+ L EMC+K++A G
Sbjct: 210 PGIMPIQAWDSFIRRAKWSGVKIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASG 269
Query: 392 FKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
LH YT+NLEK+ I++ LGL++E P
Sbjct: 270 ITRLHFYTMNLEKAVKMIIERLGLLDENLAP 300
[40][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 88.2 bits (217), Expect = 4e-16
Identities = 45/86 (52%), Positives = 55/86 (63%), Gaps = 3/86 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI +Y F RMT +C +P EI LEPIKD++EAVK G L EMC++ILA
Sbjct: 235 LPGIMPIQSYSSFTRMTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILAD 294
Query: 395 GFKTL---HLYTLNLEKSALAILKNL 327
+ H YTLNLE+SA IL L
Sbjct: 295 PIAKIDGVHFYTLNLERSATRILMQL 320
[41][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 88.2 bits (217), Expect = 4e-16
Identities = 45/110 (40%), Positives = 65/110 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G L MCKK+LA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ +L LGLI P +P Q+ G +E
Sbjct: 269 GIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[42][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 88.2 bits (217), Expect = 4e-16
Identities = 45/110 (40%), Positives = 65/110 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G L MCKK+LA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ +L LGLI P +P Q+ G +E
Sbjct: 269 GIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[43][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 88.2 bits (217), Expect = 4e-16
Identities = 45/110 (40%), Positives = 65/110 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + ALEP+K+++ AV+ G L MCKK+LA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLAS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ +L LGLI P +P Q+ G +E
Sbjct: 269 GIHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[44][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 87.8 bits (216), Expect = 5e-16
Identities = 40/85 (47%), Positives = 55/85 (64%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPG+M IN Y GF +MT FCKT++P + ++ IKD+ +AVK +G+ G E+ + +L
Sbjct: 231 VPGLMCINAYPGFKKMTKFCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDS 290
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G K LH YTLNLEK I LG+
Sbjct: 291 GVKILHFYTLNLEKVVYGITDELGI 315
[45][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 86.7 bits (213), Expect = 1e-15
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI +Y GF +MT FCKTK+P I LE +K +++ VK G+ + MC +I+++G
Sbjct: 184 PGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYG 243
Query: 392 FK------TLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 240
LH YTLNLE S I++ L +++ R P +A E RP
Sbjct: 244 VDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
[46][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 86.7 bits (213), Expect = 1e-15
Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI +Y GF +MT FCKTK+P I LE +K +++ VK G+ + MC +I+++G
Sbjct: 184 PGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYG 243
Query: 392 FK------TLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 240
LH YTLNLE S I++ L +++ R P +A E RP
Sbjct: 244 VDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
[47][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 86.7 bits (213), Expect = 1e-15
Identities = 46/117 (39%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + + KIP + LEP+KD+++ V+ G L +MC+KIL
Sbjct: 214 IPGIMPITTYAAFLRRAQWGQIKIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNS 273
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 228
G+ K LH+YT+NLEK+ L IL+ LGL+ S P ++ ++ N +R E++
Sbjct: 274 GYVKHLHIYTMNLEKAPLIILEKLGLLPSESEVNANPLASLPWRK-SLNPKRKNEEV 329
[48][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 86.7 bits (213), Expect = 1e-15
Identities = 42/98 (42%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y FIR + + KT+IP + + ALEP+K+++ AV+ G L +MC++++A
Sbjct: 209 IPGIMPIQTYAAFIRRSDWTKTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLI--EETSIPRTRP 288
G LH YT+NL +S +L L L+ EET + R P
Sbjct: 269 GINHLHFYTMNLAQSTQLVLDELNLMPSEETPLQRALP 306
[49][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 85.9 bits (211), Expect = 2e-15
Identities = 44/110 (40%), Positives = 65/110 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G L MC+KILA
Sbjct: 100 IPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAA 159
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ +L L LI P +P Q+ G +E
Sbjct: 160 GIYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREE 209
[50][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 85.9 bits (211), Expect = 2e-15
Identities = 44/110 (40%), Positives = 65/110 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + K +IP + + ALEP+K+++ AV+ G L MC+KILA
Sbjct: 209 IPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL+++ +L L LI P +P Q+ G +E
Sbjct: 269 GIYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREE 318
[51][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 85.5 bits (210), Expect = 3e-15
Identities = 41/96 (42%), Positives = 59/96 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + K K+P M ALEP+K+++ AVK G L MC+KIL
Sbjct: 209 LPGIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G + LH YT+NL ++ +L+ L LI P +P
Sbjct: 269 GIRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKP 304
[52][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 85.5 bits (210), Expect = 3e-15
Identities = 41/96 (42%), Positives = 59/96 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + K K+P M ALEP+K+++ AVK G L MC+KIL
Sbjct: 209 LPGIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDS 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G + LH YT+NL ++ +L+ L LI P +P
Sbjct: 269 GIRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKP 304
[53][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 85.1 bits (209), Expect = 3e-15
Identities = 40/96 (41%), Positives = 58/96 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + K +IP E + ALEP+K+++ AVK G L +MC+++LA
Sbjct: 209 IPGIMPIQTYAAFMRRANWTKIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL +S +L+ L L P +P
Sbjct: 269 GINHLHFYTMNLAQSTQLVLEELNLTPSEETPLQKP 304
[54][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 84.3 bits (207), Expect = 6e-15
Identities = 41/88 (46%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + IP + ALEPIK+++ V+A G L +EMC K++
Sbjct: 209 IPGIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKS 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLE++ + IL+NL LIE
Sbjct: 269 GYVNHLHFYTMNLERATIMILENLNLIE 296
[55][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 84.3 bits (207), Expect = 6e-15
Identities = 41/88 (46%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + IP + ALEPIK+++ V+A G L +EMC K++
Sbjct: 209 IPGIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKS 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLE++ + IL+NL LIE
Sbjct: 269 GYVNHLHFYTMNLERATIMILENLNLIE 296
[56][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 84.0 bits (206), Expect = 8e-15
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIM I N GF RMT FCK++ PA + AA+E D++EA++ + G ++C+ + A
Sbjct: 242 VPGIMCIQNAGGFKRMTAFCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAA 301
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLNLEK LAIL L L
Sbjct: 302 GAPGLHFYTLNLEKVTLAILDALNL 326
[57][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 84.0 bits (206), Expect = 8e-15
Identities = 38/91 (41%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R +C ++P + L P+ D++E V+ G L +MC+++L
Sbjct: 202 IPGIMPISTYAAFLRRCSWCGVRVPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLES 261
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETS 306
G + LHLYT+NLE+ L IL+ LGL+ E S
Sbjct: 262 GVVSHLHLYTMNLERPPLVILERLGLLPEAS 292
[58][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 83.6 bits (205), Expect = 1e-14
Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 10/114 (8%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + IP + AL+PIKD++ V+ G L +EMC+K+L
Sbjct: 209 IPGIMPISTYSAFLRRAKWSEIAIPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLES 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE---------TSIPRTRPANAIQAKE 264
G+ LH YT+NLEK+ + IL+ L LIE T +P + N ++KE
Sbjct: 269 GYINHLHFYTMNLEKATVMILEKLNLIEAVKSNEIVGVTELPWRKSLNPERSKE 322
[59][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 83.6 bits (205), Expect = 1e-14
Identities = 42/91 (46%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI NY F RM C P +++ LEPIK ++ VK +GIHL +M K I
Sbjct: 236 IPGIMPIQNYTMFRRMANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQ 295
Query: 395 -GFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G + HLYTLNLEKSA ++K L + + S
Sbjct: 296 TGIRAFHLYTLNLEKSATCVIKVLADVPDQS 326
[60][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 83.6 bits (205), Expect = 1e-14
Identities = 40/88 (45%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + KIP + ALEPIKD++ V+ G L +EMC++++
Sbjct: 210 IPGIMPISTYAAFIRRAKWSEIKIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIES 269
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLEK+ + IL+ L L+E
Sbjct: 270 GYVNHLHFYTMNLEKATVMILEKLNLVE 297
[61][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 83.2 bits (204), Expect = 1e-14
Identities = 41/88 (46%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-- 402
VPGIMPI + GFI+ T TKIP + ALEP+K ++E V+ G L +MC+KIL
Sbjct: 170 VPGIMPIQTWNGFIKATNLASTKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDS 229
Query: 401 AHGFKTLHLYTLNLEKSALAILKNLGLI 318
G + LH YT+NLEK +L+ L L+
Sbjct: 230 GLGIRGLHFYTMNLEKGTRMLLEELNLV 257
[62][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 82.4 bits (202), Expect = 2e-14
Identities = 38/88 (43%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + IP + AL PIK+++ A++ G L +EMC+K++
Sbjct: 212 IPGIMPISTYSAFIRRANWSQVAIPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDS 271
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLE+S + IL+ L L+E
Sbjct: 272 GYVNHLHFYTMNLERSTVMILEKLNLVE 299
[63][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 82.0 bits (201), Expect = 3e-14
Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R +C+ +IP + + LEP+KD++ V+ G L +MC+K+L
Sbjct: 210 IPGIMPISTYASFMRRANWCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDS 269
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEETS 306
G K LH YT+NLEK+ + +L+ L L + S
Sbjct: 270 GKIKHLHFYTMNLEKATVMVLERLNLPAQDS 300
[64][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 82.0 bits (201), Expect = 3e-14
Identities = 41/88 (46%), Positives = 57/88 (64%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + IP + AL+PIKD++ V+ G L +EMC K+L
Sbjct: 209 IPGIMPISTYAAFIRRAKWSEIAIPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQS 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLEK+ + IL+ L LIE
Sbjct: 269 GYVNHLHFYTMNLEKATVMILEKLNLIE 296
[65][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 81.6 bits (200), Expect = 4e-14
Identities = 41/88 (46%), Positives = 57/88 (64%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y FIR + + IP + AL+PIKD++ V+ G L +EMC K+L
Sbjct: 209 IPGIMPISTYAAFIRRAKWSEIVIPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQS 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
G+ LH YT+NLEK+ + IL+ L LIE
Sbjct: 269 GYVNHLHFYTMNLEKATVMILEKLNLIE 296
[66][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 81.6 bits (200), Expect = 4e-14
Identities = 42/98 (42%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y FIR + K IP + + LEP+K+++ AVK G L +MC+++LA
Sbjct: 209 IPGIMPIQTYAAFIRRANWTKIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLI--EETSIPRTRP 288
G LH YT+NL ++ +L L L+ EET I R P
Sbjct: 269 GINHLHFYTMNLAQATQLVLDELKLLPSEETPIQRPLP 306
[67][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 81.3 bits (199), Expect = 5e-14
Identities = 43/85 (50%), Positives = 54/85 (63%), Gaps = 1/85 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LA 399
+PGIMPI NY F RMT CK ++P I+ ALEPIK ++ AVK YG+ L M +I L
Sbjct: 272 LPGIMPIQNYSSFRRMTNLCKVQVPQLILDALEPIKSDDAAVKEYGVSLSIHMVGRIFLE 331
Query: 398 HGFKTLHLYTLNLEKSALAILKNLG 324
+ HL +LNLEKS IL+ LG
Sbjct: 332 TDVRGFHLCSLNLEKSIERILEGLG 356
[68][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 80.9 bits (198), Expect = 7e-14
Identities = 39/89 (43%), Positives = 54/89 (60%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L MCK++LA
Sbjct: 247 LPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLAS 306
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 307 GLVPGLHFYTLNREVATMEVLKRLGMWNE 335
[69][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 80.9 bits (198), Expect = 7e-14
Identities = 43/110 (39%), Positives = 60/110 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y FIR KIP E MA LEP+K+++ AV+ G L EMC+KI+
Sbjct: 209 IPGIMPIATYASFIRRANHMNCKIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G + LH YT+NL ++ +L+ L + + P R Q+ G E
Sbjct: 269 GIRHLHFYTMNLAQATRMVLEELDWLPSPNRPLKRALPWKQSLGSGRRDE 318
[70][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 80.9 bits (198), Expect = 7e-14
Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +L EMC+K+L
Sbjct: 214 IPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDS 273
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 228
G+ + LH+YT+NLEK+ L IL+ L ++ S P A+ N +R E++
Sbjct: 274 GYVSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[71][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 80.9 bits (198), Expect = 7e-14
Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +L EMC+K+L
Sbjct: 214 IPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDS 273
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 228
G+ + LH+YT+NLEK+ L IL+ L ++ S P A+ N +R E++
Sbjct: 274 GYVSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[72][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 80.5 bits (197), Expect = 9e-14
Identities = 38/89 (42%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI A +EPIKDN+ A++ YGI L MC+++L
Sbjct: 250 LPGIFPIQGYHSLRQLVKLSKLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVS 309
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEE 312
G + LH YTLN E + + +LK LG+ E
Sbjct: 310 GVVSGLHFYTLNREVATVEVLKRLGIWNE 338
[73][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 80.5 bits (197), Expect = 9e-14
Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +L EMC+K+L
Sbjct: 25 IPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDS 84
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 228
G+ + LH+YT+NLEK+ L IL+ L ++ S P A+ N +R E++
Sbjct: 85 GYVSHLHIYTMNLEKAPLMILERLNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 140
[74][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 80.5 bits (197), Expect = 9e-14
Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + + IP + L+PIKD++E V+ G +L EMC+K+L
Sbjct: 214 IPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDS 273
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 228
G+ + LH+YT+NLEK+ L IL+ L ++ S P A+ N +R E++
Sbjct: 274 GYVSHLHIYTMNLEKAPLMILERLNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[75][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 80.1 bits (196), Expect = 1e-13
Identities = 42/110 (38%), Positives = 64/110 (58%), Gaps = 5/110 (4%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA- 399
+PGI+PI Y + K +P I+ +E IKDN+EA++ +GI T +CKK+LA
Sbjct: 236 IPGILPIQGYNSLRHLVQLSKLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLAS 295
Query: 398 HGFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP----ANAIQAKED 261
+H+YTLN E++ + +LK +GL E SI ++ P AN + ED
Sbjct: 296 DDVPGIHVYTLNREEAVVKLLKRVGLWHEESIYKSLPWRPSANGKRISED 345
[76][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 80.1 bits (196), Expect = 1e-13
Identities = 38/88 (43%), Positives = 56/88 (63%), Gaps = 1/88 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + IP + LEPIKD++ V+ G L ++MC K+L
Sbjct: 209 IPGIMPISTYAAFVRRAKWSQIAIPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQS 268
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIE 315
GF LH YT+NLE++ + IL+ L +IE
Sbjct: 269 GFVNHLHFYTMNLERATIMILETLNIIE 296
[77][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 79.7 bits (195), Expect = 1e-13
Identities = 39/89 (43%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y+ ++ K ++P EI + LEPIKDN+ A++ YGI L EMC+ +L
Sbjct: 257 LPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDS 316
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +L+ LGL E
Sbjct: 317 GKVPGLHFYTLNREVATMEVLRQLGLWTE 345
[78][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 79.7 bits (195), Expect = 1e-13
Identities = 40/92 (43%), Positives = 54/92 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C +IP I LE D+ E+++ +G + T MC+K+L
Sbjct: 226 VPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKA 285
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G LH YTLN + +L I KNLGL E IP
Sbjct: 286 GAPGLHFYTLNQVEPSLGIWKNLGLGEREKIP 317
[79][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 79.7 bits (195), Expect = 1e-13
Identities = 42/110 (38%), Positives = 60/110 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R K KIP + ALEP+K+++ AV+ G L EMC+K+LA+
Sbjct: 209 LPGIMPIATYASFLRRANHMKAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLAN 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL ++ +L+ L P Q+K G +E
Sbjct: 269 GIHHLHFYTMNLAQATRMVLEELNWAPSAERPLQHALPWKQSKGLGRREE 318
[80][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 79.3 bits (194), Expect = 2e-13
Identities = 38/89 (42%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI L MC+++L
Sbjct: 247 LPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDS 306
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ +E
Sbjct: 307 GLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[81][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 79.3 bits (194), Expect = 2e-13
Identities = 38/89 (42%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI L MC+++L
Sbjct: 247 LPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDS 306
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ +E
Sbjct: 307 GLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[82][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 79.3 bits (194), Expect = 2e-13
Identities = 39/89 (43%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI EMCK +LA
Sbjct: 253 LPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLAS 312
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +L+ LGL E
Sbjct: 313 GEVSGLHFYTLNREVATMEVLRQLGLWAE 341
[83][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 79.3 bits (194), Expect = 2e-13
Identities = 38/89 (42%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EIM +EPIKDN+ A++ YGI L MC+++L
Sbjct: 247 LPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDS 306
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ +E
Sbjct: 307 GLVHGLHFYTLNREVATIDVLKRLGMWKE 335
[84][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 79.0 bits (193), Expect = 2e-13
Identities = 39/92 (42%), Positives = 55/92 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + +IP E + LEPIK ++ AV+ G L E+C+KILA
Sbjct: 204 IPGIMPIATYASFLRRANHMQARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAA 263
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G LH YT+NL +S IL++L + + P
Sbjct: 264 GIHHLHFYTMNLAQSTALILEDLDWLPSPNKP 295
[85][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 78.6 bits (192), Expect = 3e-13
Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C+++LA
Sbjct: 276 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLAS 335
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 336 GLVPGLHFYTLNREMATTEVLKRLGMWTE 364
[86][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 78.6 bits (192), Expect = 3e-13
Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C+++LA
Sbjct: 294 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLAS 353
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 354 GLVPGLHFYTLNREMATTEVLKRLGMWTE 382
[87][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 78.6 bits (192), Expect = 3e-13
Identities = 36/83 (43%), Positives = 51/83 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI NY +R + C IPA + ++PI+D+ EAVKA GI L + C+++L
Sbjct: 165 IPGIMPIGNYDQIVRFSSMCGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQA 224
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN ++ +AI L
Sbjct: 225 GVPGLHFYTLNKSEATIAIRNQL 247
[88][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 78.6 bits (192), Expect = 3e-13
Identities = 42/109 (38%), Positives = 61/109 (55%), Gaps = 4/109 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PG+MPI Y + K +IP EI A+EPI+DN+EA++ YG+H M +++
Sbjct: 242 IPGVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDS 301
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE---TSIPRTRPANAIQAKED 261
G LH YTLN E + + ILK +GL E P R AN + +E+
Sbjct: 302 GLVNGLHFYTLNREVATIQILKQIGLWTEDIQRPWPWKRTANYNRCEEE 350
[89][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 78.6 bits (192), Expect = 3e-13
Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C+++LA
Sbjct: 253 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLAS 312
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 313 GLVPGLHFYTLNREMATTEVLKRLGMWTE 341
[90][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 78.6 bits (192), Expect = 3e-13
Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C+++LA
Sbjct: 283 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLAS 342
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 343 GLVPGLHFYTLNREMATTEVLKRLGMWTE 371
[91][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 77.8 bits (190), Expect = 6e-13
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+ L MC+++L
Sbjct: 255 IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS 314
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LGL E
Sbjct: 315 GMVHGLHFYTLNREVATTEVLKRLGLWNE 343
[92][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 77.8 bits (190), Expect = 6e-13
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+ L MC+++L
Sbjct: 255 IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS 314
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LGL E
Sbjct: 315 GMVHGLHFYTLNREVATTEVLKRLGLWNE 343
[93][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 77.8 bits (190), Expect = 6e-13
Identities = 38/89 (42%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C ++LA
Sbjct: 276 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLAS 335
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 336 GLVPGLHFYTLNREMATTEVLKRLGMWTE 364
[94][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 77.8 bits (190), Expect = 6e-13
Identities = 38/89 (42%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C ++LA
Sbjct: 294 VPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLAS 353
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 354 GLVPGLHFYTLNREMATTEVLKRLGMWTE 382
[95][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 77.8 bits (190), Expect = 6e-13
Identities = 39/85 (45%), Positives = 53/85 (62%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP + LE D+ ++++A+G + TEMC+K+LA
Sbjct: 197 VPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAG 256
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NLGL
Sbjct: 257 GAPGLHFYTLNQAEPSLAIWNNLGL 281
[96][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 77.8 bits (190), Expect = 6e-13
Identities = 36/84 (42%), Positives = 52/84 (61%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGI+PI + R++ C K+P+ +++ LE + DN+EA AYGI TE C ++L G
Sbjct: 218 PGILPILSAGQIKRISALCGAKLPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREG 277
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
LH+YTLN S + +LKNL L
Sbjct: 278 APGLHMYTLNKAPSTIQVLKNLAL 301
[97][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 77.8 bits (190), Expect = 6e-13
Identities = 37/88 (42%), Positives = 55/88 (62%), Gaps = 4/88 (4%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMP+ +Y ++MT FC +P+ +M L I+ ++EAVK G + EMC++IL+
Sbjct: 200 IPGIMPVQSYSSLVKMTQFCGISVPSAVMDRLSNIRLDDEAVKQVGCKIVAEMCEQILSA 259
Query: 395 GFKT----LHLYTLNLEKSALAILKNLG 324
G + H YTLNLE+S IL +LG
Sbjct: 260 GLEVDVDGFHFYTLNLERSTTRILTSLG 287
[98][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 77.8 bits (190), Expect = 6e-13
Identities = 39/97 (40%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+ Y F+R + + K +IP + + LEP+K ++ V+ G L EMC+K+LA
Sbjct: 209 VPGIMPISTYDAFMRRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLAS 268
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ IL+ L L+ P +P
Sbjct: 269 GHIHHLHFYTMNLAQATRLILEELRLLPSEEAPLQKP 305
[99][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 77.8 bits (190), Expect = 6e-13
Identities = 38/88 (43%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI + GF R T K +P + ALEPIK+++E V+ G L +MC++IL
Sbjct: 210 VPGIAPIQTWNGFQRATSLAKIVVPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKE 269
Query: 395 --GFKTLHLYTLNLEKSALAILKNLGLI 318
G + LH YT+NLEK +L+ L L+
Sbjct: 270 DIGIRGLHFYTMNLEKGTKMLLEELNLV 297
[100][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 77.4 bits (189), Expect = 7e-13
Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y+ ++ K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L
Sbjct: 257 LPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDS 316
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + + +L+ LGL IE+ P
Sbjct: 317 GKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRP 350
[101][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 77.4 bits (189), Expect = 7e-13
Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y+ ++ K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L
Sbjct: 257 LPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDS 316
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + + +L+ LGL IE+ P
Sbjct: 317 GKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRP 350
[102][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 77.4 bits (189), Expect = 7e-13
Identities = 39/91 (42%), Positives = 54/91 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ R + C +IP I LE D+ ++++ +G + TEMC K+LA
Sbjct: 197 VPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRKFGEEVVTEMCAKLLAA 256
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI 303
G LH YTLN + +L+I KNLG+ E I
Sbjct: 257 GAPGLHFYTLNQAEPSLSIWKNLGIGEREKI 287
[103][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 77.0 bits (188), Expect = 9e-13
Identities = 36/89 (40%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+ L MC+++L
Sbjct: 111 IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS 170
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 171 GLVHGLHFYTLNREVATTEVLKRLGIWNE 199
[104][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 77.0 bits (188), Expect = 9e-13
Identities = 41/110 (37%), Positives = 60/110 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R + KIP E + ALEP+K+++ AV+ G L MC+K+LA+
Sbjct: 209 LPGIMPIATYASFLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLAN 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 246
G LH YT+NL ++ +L+ L P Q+K G +E
Sbjct: 269 GIHHLHFYTMNLAQATRMLLEELQWAPSADRPLQHALPWKQSKGLGRREE 318
[105][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 77.0 bits (188), Expect = 9e-13
Identities = 36/89 (40%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YG+ L MC+++L
Sbjct: 243 IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS 302
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 303 GLVHGLHFYTLNREVATTEVLKRLGIWNE 331
[106][TOP]
>UniRef100_A1U549 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter aquaeolei
VT8 RepID=A1U549_MARAV
Length = 289
Score = 77.0 bits (188), Expect = 9e-13
Identities = 37/91 (40%), Positives = 55/91 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C +IP I LE D+ ++++ +G + TEMC+K+L
Sbjct: 197 VPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRKFGEEVVTEMCQKLLKA 256
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSI 303
G LH YTLN + +L+I KNLG+ + I
Sbjct: 257 GAPGLHFYTLNQAEPSLSIWKNLGISDREKI 287
[107][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 77.0 bits (188), Expect = 9e-13
Identities = 37/93 (39%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R +C IP E L+PIKD+++ V+ G L +C+K+L
Sbjct: 213 IPGIMPITTYAAFLRRANWCDVHIPQEYFDRLDPIKDDDQLVREVGTDLIVSLCQKLLDS 272
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGLIEETSIP 300
G+ + LH+YT+NLEK+ IL + L+ P
Sbjct: 273 GYVSHLHIYTMNLEKAPQMILDRMELLPSHDEP 305
[108][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 76.6 bits (187), Expect = 1e-12
Identities = 34/85 (40%), Positives = 52/85 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI NY +R + C T+IP I LE D+ E+++A+G+ + TE+C+++L
Sbjct: 36 IPGIMPITNYSSLVRFSDACGTEIPRWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEG 95
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YT+N + L + LGL
Sbjct: 96 GAPGLHFYTMNQSEPTLRLCDRLGL 120
[109][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 76.6 bits (187), Expect = 1e-12
Identities = 37/85 (43%), Positives = 54/85 (63%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI NYK R + C +IP + ALE D+EE+++A+G+ L TE+C+ +L +
Sbjct: 195 PGIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEESLRAFGVDLVTELCEVLLENE 254
Query: 392 FKTLHLYTLNLEKSALAILKNLGLI 318
LH YT+N + I++NLGLI
Sbjct: 255 APGLHFYTMNQTEPTAQIVRNLGLI 279
[110][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 76.6 bits (187), Expect = 1e-12
Identities = 38/97 (39%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F+R + + K +IP + + LEP+K ++ V+ G L EMC+K+LA
Sbjct: 209 IPGIMPISTYDAFMRRSNWTKIRIPPDWLDKLEPVKADDAKVREIGTKLVAEMCRKLLAS 268
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ IL+ L L+ P +P
Sbjct: 269 GQIHHLHFYTMNLAQATRLILEELRLLPSEEAPLHKP 305
[111][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 76.6 bits (187), Expect = 1e-12
Identities = 35/87 (40%), Positives = 55/87 (63%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI ++ F R + +IP + ALEP+KD++ V+ G L EMC+K++ +G
Sbjct: 211 PGIMPIQSWSTFNRRCEWSGVRIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNG 270
Query: 392 FKTLHLYTLNLEKSALAILKNLGLIEE 312
LH YT+NLEK+ I++ +GL+ +
Sbjct: 271 ITRLHFYTMNLEKATKMIIEKMGLLNQ 297
[112][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 76.6 bits (187), Expect = 1e-12
Identities = 38/89 (42%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI L +C ++LA
Sbjct: 253 VPGIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLAS 312
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + +LK LG+ E
Sbjct: 313 GLVPGLHFYTLNREMATTEVLKRLGMWTE 341
[113][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 76.3 bits (186), Expect = 2e-12
Identities = 37/92 (40%), Positives = 54/92 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPIN Y F+R KIP + A+LE +K+++ AV+ G L EMC++I+
Sbjct: 209 IPGIMPINTYASFLRRCNHMGCKIPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G LH YT+NL ++ +L+ L L T P
Sbjct: 269 GVHHLHFYTMNLAQATRMVLEELNLTPSTQRP 300
[114][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 75.9 bits (185), Expect = 2e-12
Identities = 37/86 (43%), Positives = 50/86 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI R C K+PA+ + L+ + ++EAV AYGI TE C +L
Sbjct: 210 VPGIMPILTAGQTRRFVSLCGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEF 269
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLI 318
G LH YTLN +S + I++NLGL+
Sbjct: 270 GVPGLHFYTLNKARSTVQIVRNLGLL 295
[115][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 75.9 bits (185), Expect = 2e-12
Identities = 37/83 (44%), Positives = 51/83 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F+R KIP E M LEP+K+++ AV+ G L E+C+KILA
Sbjct: 209 IPGIMPIATYASFLRRANHMNCKIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YT+NL ++ +L+ L
Sbjct: 269 GIHHLHFYTMNLAQATRMVLEEL 291
[116][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 75.5 bits (184), Expect = 3e-12
Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI +C+++LA
Sbjct: 252 LPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLAS 311
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + + +LK LGL IE+ P
Sbjct: 312 GLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRP 345
[117][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 75.5 bits (184), Expect = 3e-12
Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+ G++PI Y GF RM CKT++P ++ +E +K+N EA+K YG+ +M ++I A
Sbjct: 220 IAGLLPITTYAGFTRMVSLCKTRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRAS 279
Query: 395 G--FKTLHLYTLNLEKSALAILKNLGLIEE 312
G + LH YTLN +LK L + E
Sbjct: 280 GLDYHHLHFYTLNSSAQTFQVLKRLNALVE 309
[118][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 75.5 bits (184), Expect = 3e-12
Identities = 37/92 (40%), Positives = 54/92 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI Y F+R K+P E MA LE +K+++ AV+ G L +MC+KIL+
Sbjct: 209 VPGIMPIATYASFLRRANHMNCKVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G + LH YT+NL ++ +L+ L + P
Sbjct: 269 GIRHLHFYTMNLAQATRMVLEELDWLPSPDRP 300
[119][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 75.5 bits (184), Expect = 3e-12
Identities = 34/96 (35%), Positives = 57/96 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ + F+R + + IP ALEP+K+++ V+ G L +MC+K++A
Sbjct: 209 IPGIMPIHTHAAFLRRAQWTRCNIPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ +L+ L L+ + P +P
Sbjct: 269 GITHLHFYTMNLAQATRMVLEELDLLPDVEAPLEKP 304
[120][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 75.5 bits (184), Expect = 3e-12
Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI +C+++LA
Sbjct: 252 LPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLAS 311
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + + +LK LGL IE+ P
Sbjct: 312 GLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRP 345
[121][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 75.1 bits (183), Expect = 4e-12
Identities = 39/85 (45%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI NY F R+ K +P I + L+PI ++ VK YG L T+M +I+
Sbjct: 212 IPGIMPIQNYASFRRLVNLTKCPVPDSITSDLQPISSDDATVKRYGAELATKMVSQIIES 271
Query: 395 GF-KTLHLYTLNLEKSALAILKNLG 324
G +HL TLNLEKS IL NLG
Sbjct: 272 GLVPGVHLCTLNLEKSVRMILDNLG 296
[122][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 75.1 bits (183), Expect = 4e-12
Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGT---EMCKKI 405
+PG+MPI++YK R T KIP +IM+ LE +K +++AVK G+ + + E KKI
Sbjct: 223 IPGLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEE 312
GF+ H YTLNLEK+ I++ GLI +
Sbjct: 283 PCPGFRGFHFYTLNLEKTVSFIIERCGLIPD 313
[123][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 75.1 bits (183), Expect = 4e-12
Identities = 38/87 (43%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PG+MPI Y GF R T T +P AL+P++D+++ V+ G L EMCKKI+
Sbjct: 226 IPGVMPIQTYGGFQRATARFGTLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGT 285
Query: 395 --GFKTLHLYTLNLEKSALAILKNLGL 321
G LH+YT+NLEK + +L LGL
Sbjct: 286 GLGISGLHIYTMNLEKGSRMLLDYLGL 312
[124][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 75.1 bits (183), Expect = 4e-12
Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGT---EMCKKI 405
+PG+MPI++YK R T KIP +IM+ LE +K +++AVK G+ + + E KKI
Sbjct: 223 IPGLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEE 312
GF+ H YTLNLEK+ I++ GLI +
Sbjct: 283 PCPGFRGFHFYTLNLEKTVSFIIERCGLIPD 313
[125][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 75.1 bits (183), Expect = 4e-12
Identities = 39/98 (39%), Positives = 56/98 (57%), Gaps = 1/98 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LA 399
+PGIMPI Y F+R+T C T++PA I L PI +++ VK YG+ L +M +++ L
Sbjct: 211 IPGIMPIQTYASFVRLTKLCGTRVPACITEDLAPISHDDQLVKDYGVKLAVQMIRRLRLE 270
Query: 398 HGFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPA 285
G + H TLNLEKS +L+ L +T PA
Sbjct: 271 GGIQGFHFCTLNLEKSVQRVLETLRWAGDTPGTMEPPA 308
[126][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 75.1 bits (183), Expect = 4e-12
Identities = 37/92 (40%), Positives = 53/92 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPIN Y F+R KIP + AALE +K+++ AV+ G L EMC++I+
Sbjct: 209 IPGIMPINTYASFLRRCNHMGCKIPPKWSAALEEVKNDDAAVRNIGKDLVAEMCRRIIEA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G LH YT+NL ++ +L+ L L P
Sbjct: 269 GVHHLHFYTMNLAQATRMVLEELSLTPSNQRP 300
[127][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 75.1 bits (183), Expect = 4e-12
Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGT---EMCKKI 405
+PG+MPI++YK R T KIP +IM+ LE +K +++AVK G+ + + E KKI
Sbjct: 250 IPGLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKI 309
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEE 312
GF+ H YTLNLEK+ I++ GLI +
Sbjct: 310 PCPGFRGFHFYTLNLEKTVSFIIERCGLIPD 340
[128][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 74.7 bits (182), Expect = 5e-12
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 293 LPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDS 352
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 353 GLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[129][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 74.7 bits (182), Expect = 5e-12
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 293 LPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDS 352
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 353 GLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[130][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 74.7 bits (182), Expect = 5e-12
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 293 LPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDS 352
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 353 GLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[131][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 74.7 bits (182), Expect = 5e-12
Identities = 34/85 (40%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C IP I LE D+ +A++ +G+ + TE+C+++L
Sbjct: 202 VPGIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDRKAIRTFGLEVVTELCRRLLEQ 261
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN ++ L + K LGL
Sbjct: 262 GAPGLHFYTLNRAEACLEVWKALGL 286
[132][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 74.7 bits (182), Expect = 5e-12
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 252 LPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDS 311
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 312 GLVPGLHFYTLNREVATMEVLKQLGMWTE 340
[133][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 74.3 bits (181), Expect = 6e-12
Identities = 36/85 (42%), Positives = 52/85 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP + LE D+ ++++A+G + TEMC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFGEQVITEMCERLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH Y++NL +LAI NLGL
Sbjct: 255 GAPGLHFYSMNLAGPSLAIWNNLGL 279
[134][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 74.3 bits (181), Expect = 6e-12
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +
Sbjct: 245 IPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDN 304
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL 321
G ++HLYT+N E S ILK+LGL
Sbjct: 305 GTAPSIHLYTMNREGSIREILKSLGL 330
[135][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 74.3 bits (181), Expect = 6e-12
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +
Sbjct: 266 IPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDN 325
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL 321
G ++HLYT+N E S ILK+LGL
Sbjct: 326 GTAPSIHLYTMNREGSIREILKSLGL 351
[136][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 73.9 bits (180), Expect = 8e-12
Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 258 LPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDS 317
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 318 GLVPGLHFYTLNREVATMEVLKQLGMWTE 346
[137][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 73.9 bits (180), Expect = 8e-12
Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P I +EPIKDN+ A++ YGI L +C+++L
Sbjct: 293 LPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDS 352
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEE 312
G LH YTLN E + + +LK LG+ E
Sbjct: 353 GLVPGLHFYTLNREVATMEVLKQLGMWTE 381
[138][TOP]
>UniRef100_C1DIB8 Methylenetetrahydrofolate reductase n=1 Tax=Azotobacter vinelandii
DJ RepID=C1DIB8_AZOVD
Length = 281
Score = 73.9 bits (180), Expect = 8e-12
Identities = 37/85 (43%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C ++P + LE D+ E+++A+G + T MC+K+L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFGEQVVTAMCEKLLEG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NLGL
Sbjct: 255 GAPGLHFYTLNQAEPSLAIWNNLGL 279
[139][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 73.9 bits (180), Expect = 8e-12
Identities = 35/93 (37%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ Y F R +C+ +P+ L+ KD++ V+ G L +MC K++
Sbjct: 195 IPGIMPISTYASFSRRAKWCQINVPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVES 254
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G+ LH YT+NLEKS + +L+ L LI+ + P
Sbjct: 255 GYVNHLHFYTMNLEKSTIMVLEKLQLIDTHNQP 287
[140][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 73.6 bits (179), Expect = 1e-11
Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P EI +EPIKDN+ A++ YGI +C+++LA
Sbjct: 252 LPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLAS 311
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN E + +LK LG+
Sbjct: 312 GLVPGLHFYTLNREVATTEVLKRLGM 337
[141][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 73.6 bits (179), Expect = 1e-11
Identities = 38/86 (44%), Positives = 55/86 (63%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +
Sbjct: 267 IPGIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDN 326
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL 321
G ++HLYT+N E S ILK LGL
Sbjct: 327 GSAPSIHLYTMNREGSIREILKALGL 352
[142][TOP]
>UniRef100_C5BTQ6 Methylenetetrahydrofolate reductase n=1 Tax=Teredinibacter turnerae
T7901 RepID=C5BTQ6_TERTT
Length = 282
Score = 73.6 bits (179), Expect = 1e-11
Identities = 35/87 (40%), Positives = 51/87 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI NY+ R + C +IP I L DN+E+++A+ L TE+C +L +
Sbjct: 196 IPGIMPITNYQNIARFSDACGAEIPRWIRKRLNDFGDNQESLQAFTTDLVTELCATLLEN 255
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIE 315
G LH YT+N + IL NLGL++
Sbjct: 256 GAPGLHFYTMNQVEPTRTILTNLGLVD 282
[143][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 73.6 bits (179), Expect = 1e-11
Identities = 38/86 (44%), Positives = 55/86 (63%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y+ R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +
Sbjct: 317 IPGIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDN 376
Query: 395 G-FKTLHLYTLNLEKSALAILKNLGL 321
G ++HLYT+N E S ILK LGL
Sbjct: 377 GSAPSIHLYTMNREGSIREILKALGL 402
[144][TOP]
>UniRef100_C6P2D6 Methylenetetrahydrofolate reductase n=1 Tax=Sideroxydans
lithotrophicus ES-1 RepID=C6P2D6_9GAMM
Length = 280
Score = 73.2 bits (178), Expect = 1e-11
Identities = 34/84 (40%), Positives = 53/84 (63%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI + R + C +IP + +E D+ E+V+A+G+ + T++C+K++A
Sbjct: 195 VPGIMPIGRFSQLARFSDNCGAEIPRWMRKTMEGYGDDSESVQAFGLDVVTQLCEKLIAG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G +LH YTLN ++L ILK LG
Sbjct: 255 GAPSLHFYTLNQANASLEILKRLG 278
[145][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 72.8 bits (177), Expect = 2e-11
Identities = 38/110 (34%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-A 399
+PG+MPI Y +++ K ++P I+ LEPIK+++EA++ YG+ L MC+++L +
Sbjct: 230 IPGVMPIQAYASLLQLVKLSKLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSS 289
Query: 398 HGFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP----ANAIQAKED 261
+H+YTLN E + +L+ LGL R P AN + +ED
Sbjct: 290 DDVPGIHVYTLNREVATTELLQQLGLWRPYQSHRLLPWKPSANLKRLQED 339
[146][TOP]
>UniRef100_Q2L158 Methylenetetrahydrofolate reductase n=1 Tax=Bordetella avium 197N
RepID=Q2L158_BORA1
Length = 280
Score = 72.8 bits (177), Expect = 2e-11
Identities = 33/83 (39%), Positives = 51/83 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C ++P I L D++ +++A+G+ + T++C+ +L H
Sbjct: 196 VPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAFGVDVVTKLCQTLLDH 255
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN ++ L+I KNL
Sbjct: 256 GVPGLHFYTLNQSEATLSIWKNL 278
[147][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 72.8 bits (177), Expect = 2e-11
Identities = 35/86 (40%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI+PI +Y+ R+ + IP I+ +LEPIK++++AV+ +GI +C+ +L++
Sbjct: 264 IPGILPIQSYESIRRVAELSQLVIPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSN 323
Query: 395 GFKT-LHLYTLNLEKSALAILKNLGL 321
G T +HL+TLN E S+ IL+ LGL
Sbjct: 324 GSATSIHLFTLNREASSREILQQLGL 349
[148][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 72.4 bits (176), Expect = 2e-11
Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI +C+++L
Sbjct: 378 LPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTS 437
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + +LK LG+ IE+ P
Sbjct: 438 GLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRP 471
[149][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 72.4 bits (176), Expect = 2e-11
Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGI PI Y ++ K ++P +I +EPIKDN+ A++ YGI +C+++L
Sbjct: 294 LPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTS 353
Query: 395 GF-KTLHLYTLNLEKSALAILKNLGL-IEETSIP 300
G LH YTLN E + +LK LG+ IE+ P
Sbjct: 354 GLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRP 387
[150][TOP]
>UniRef100_Q476T6 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha
JMP134 RepID=Q476T6_RALEJ
Length = 276
Score = 72.0 bits (175), Expect = 3e-11
Identities = 33/85 (38%), Positives = 52/85 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY +R + C +++P + LE D+ E+++A+G+ + T +C+++LA
Sbjct: 192 VPGIMPITNYSQLMRFSDMCGSEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + L L
Sbjct: 252 GVPGLHFYTLNAAGATKAIWQRLKL 276
[151][TOP]
>UniRef100_Q0VL81 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax borkumensis
SK2 RepID=Q0VL81_ALCBS
Length = 275
Score = 72.0 bits (175), Expect = 3e-11
Identities = 35/84 (41%), Positives = 50/84 (59%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI N +R + C +P + + L IKD++ AVKA+G + T +C+++LA G
Sbjct: 192 PGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVVTRLCERLLAMG 251
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
LH YT+N L IL NLG+
Sbjct: 252 APGLHFYTMNQAGPNLRILDNLGM 275
[152][TOP]
>UniRef100_B6J3R7 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
CbuG_Q212 RepID=B6J3R7_COXB2
Length = 290
Score = 72.0 bits (175), Expect = 3e-11
Identities = 32/83 (38%), Positives = 55/83 (66%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+
Sbjct: 195 VPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAY 254
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN + I++NL
Sbjct: 255 GVPGLHFYTLNQCEPTQTIIENL 277
[153][TOP]
>UniRef100_A9N9C8 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=A9N9C8_COXBR
Length = 290
Score = 72.0 bits (175), Expect = 3e-11
Identities = 32/83 (38%), Positives = 55/83 (66%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+
Sbjct: 195 VPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAY 254
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN + I++NL
Sbjct: 255 GVPGLHFYTLNQCEPTQTIIENL 277
[154][TOP]
>UniRef100_B6J6H7 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=B6J6H7_COXB1
Length = 290
Score = 72.0 bits (175), Expect = 3e-11
Identities = 32/83 (38%), Positives = 55/83 (66%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+++ +R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+
Sbjct: 195 VPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAY 254
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN + I++NL
Sbjct: 255 GVPGLHFYTLNQCEPTQTIIENL 277
[155][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 72.0 bits (175), Expect = 3e-11
Identities = 33/96 (34%), Positives = 56/96 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+ + F+R + + IP ALEPIK+++ V+ G L +MC++++
Sbjct: 209 IPGIMPIHTHASFLRRAQWTRCNIPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEA 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRP 288
G LH YT+NL ++ +L+ L L+ + P +P
Sbjct: 269 GITHLHFYTMNLAQATRMVLEELDLLPDPGSPLEKP 304
[156][TOP]
>UniRef100_Q84CU6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=uncultured
bacterium RepID=Q84CU6_9BACT
Length = 253
Score = 71.6 bits (174), Expect = 4e-11
Identities = 37/93 (39%), Positives = 54/93 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R +G C +IP + LE D+ +++A GI + +E+C+ +LA
Sbjct: 160 VPGIMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYADDMPSLRALGIDVVSELCEVLLAG 219
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPR 297
G +LH YTLN I+ N+GL + T+ R
Sbjct: 220 GVPSLHFYTLNQAGIISTIINNVGLEDATTQKR 252
[157][TOP]
>UniRef100_B4X3B0 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax sp. DG881
RepID=B4X3B0_9GAMM
Length = 275
Score = 71.6 bits (174), Expect = 4e-11
Identities = 35/84 (41%), Positives = 50/84 (59%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI N +R + C +P + + L IKD++ AVKA+G + T +C+++LA G
Sbjct: 192 PGIMPILNVANLLRFSSTCGADVPRWLQSKLNDIKDDDVAVKAFGEEVVTRLCERLLAMG 251
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
LH YT+N L IL NLG+
Sbjct: 252 APGLHFYTMNQAGPNLRILDNLGM 275
[158][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 71.6 bits (174), Expect = 4e-11
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI +Y R+T KIP EI+A +E K ++E VK G+ + +E+ KKI
Sbjct: 223 IPGLMPIQSYHTLTRVTKLSHAKIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G + H YTLNLEKS IL+ LI +S
Sbjct: 283 STPGHRGFHFYTLNLEKSVSFILERCNLIPPSS 315
[159][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 71.2 bits (173), Expect = 5e-11
Identities = 33/85 (38%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY +R + C ++P + LE D++EA++A+G+ + T++C ++L
Sbjct: 192 VPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDVVTDLCTRLLEA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + L L
Sbjct: 252 GVPGLHFYTLNAAGATKAIWQRLKL 276
[160][TOP]
>UniRef100_B2AGG4 Methylenetetrahydrofolate reductase n=1 Tax=Cupriavidus taiwanensis
RepID=B2AGG4_CUPTR
Length = 276
Score = 71.2 bits (173), Expect = 5e-11
Identities = 33/85 (38%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY +R + C ++P + LE D+ E+++A+G+ + T +C+++LA
Sbjct: 192 VPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + L L
Sbjct: 252 GVPGLHFYTLNAAGATKAIWQRLKL 276
[161][TOP]
>UniRef100_Q8Y389 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=Q8Y389_RALSO
Length = 276
Score = 70.9 bits (172), Expect = 7e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C +IP I LE D+ E+++A+G+ + T +C ++LA
Sbjct: 192 VPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + LGL
Sbjct: 252 GAPGLHFYTLNAAAATRAIWQRLGL 276
[162][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 70.9 bits (172), Expect = 7e-11
Identities = 37/85 (43%), Positives = 47/85 (55%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C IP I LE D+ A++A+G + T +C+K+L
Sbjct: 199 VPGIMPITNYTQLARFSDACGADIPRWIRKRLEGFGDDSAAIRAFGEDVVTRLCEKLLEA 258
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YT+N LAI NLGL
Sbjct: 259 GAPGLHFYTMNQAGPTLAIWNNLGL 283
[163][TOP]
>UniRef100_A6UYP0 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas aeruginosa
PA7 RepID=A6UYP0_PSEA7
Length = 282
Score = 70.9 bits (172), Expect = 7e-11
Identities = 36/85 (42%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C ++P I LE D+ +++A+G + +EMC+++L
Sbjct: 196 VPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAFGEQVISEMCERLLQG 255
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN +LAI KNL L
Sbjct: 256 GAPGLHFYTLNQADPSLAIWKNLQL 280
[164][TOP]
>UniRef100_B5S7H8 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=B5S7H8_RALSO
Length = 276
Score = 70.9 bits (172), Expect = 7e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C +IP I LE D+ E+++A+G+ + T +C ++LA
Sbjct: 192 VPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + LGL
Sbjct: 252 GAPGLHFYTLNAAAATRAIWQRLGL 276
[165][TOP]
>UniRef100_B7V417 Methylenetetrahydrofolate reductase n=5 Tax=Pseudomonas aeruginosa
RepID=B7V417_PSEA8
Length = 290
Score = 70.9 bits (172), Expect = 7e-11
Identities = 36/85 (42%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C ++P I LE D+ +++A+G + +EMC+++L
Sbjct: 204 VPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAFGEQVISEMCERLLEG 263
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN +LAI KNL L
Sbjct: 264 GAPGLHFYTLNQADPSLAIWKNLQL 288
[166][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 70.9 bits (172), Expect = 7e-11
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Frame = -1
Query: 569 GIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG- 393
G++PI Y GF+RM CKT +P+++ +E +K+N + +K YG+ +M + I A G
Sbjct: 222 GLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRASGL 281
Query: 392 -FKTLHLYTLNLEKSALAILKNLGLIEE 312
+ LH YTLN ILK L + E
Sbjct: 282 DYHHLHFYTLNNSAQIFKILKRLNALVE 309
[167][TOP]
>UniRef100_UPI0001AF5FB3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. oryzae str. 1_6 RepID=UPI0001AF5FB3
Length = 281
Score = 70.5 bits (171), Expect = 9e-11
Identities = 35/85 (41%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++A+G + T+MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LA+ NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAVWNNLQL 279
[168][TOP]
>UniRef100_UPI0001873BC3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. tomato T1 RepID=UPI0001873BC3
Length = 281
Score = 70.5 bits (171), Expect = 9e-11
Identities = 35/85 (41%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++A+G + T+MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLED 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LA+ NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAVWNNLQL 279
[169][TOP]
>UniRef100_Q4ZZ93 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. syringae B728a RepID=Q4ZZ93_PSEU2
Length = 281
Score = 70.5 bits (171), Expect = 9e-11
Identities = 35/85 (41%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++A+G + T+MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LA+ NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAVWNNLQL 279
[170][TOP]
>UniRef100_Q48PB6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. phaseolicola 1448A RepID=Q48PB6_PSE14
Length = 291
Score = 70.5 bits (171), Expect = 9e-11
Identities = 35/85 (41%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++A+G + T+MC+++L
Sbjct: 205 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQG 264
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LA+ NL L
Sbjct: 265 GTPGLHFYTLNQAEPSLAVWNNLQL 289
[171][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 70.5 bits (171), Expect = 9e-11
Identities = 33/90 (36%), Positives = 52/90 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP + LE D+ +++ +G + T +C+++LA
Sbjct: 197 VPGIMPITNYSNLARFSDMCGAEIPRWVRKQLEAYGDDSASIRKFGEEVVTRLCERLLAA 256
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G +H YTLN + +LA+ NL L ++ S
Sbjct: 257 GAPGIHFYTLNQAEPSLAVWDNLNLGDKIS 286
[172][TOP]
>UniRef100_A9KD99 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
Dugway 5J108-111 RepID=A9KD99_COXBN
Length = 290
Score = 70.5 bits (171), Expect = 9e-11
Identities = 31/83 (37%), Positives = 55/83 (66%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI+++ ++ + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+
Sbjct: 195 VPGIMPISDFDKLVQFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAY 254
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN + I++NL
Sbjct: 255 GVPGLHFYTLNQCEPTQTIIENL 277
[173][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 70.5 bits (171), Expect = 9e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C +IP I LE D+ E+++A+G+ + T +C ++LA
Sbjct: 192 VPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + LGL
Sbjct: 252 GAPGLHFYTLNAAGATRAIWQRLGL 276
[174][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 70.5 bits (171), Expect = 9e-11
Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 3/95 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI +Y R T K+P +IMA +E +K ++EAVK GI + E+ KK+
Sbjct: 223 IPGLMPIQSYHILTRTTKLSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKKL 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G + LH YTLNLEK+ I++ LI +S P
Sbjct: 283 PCPGPRGLHFYTLNLEKAVAFIVERCSLIPASSEP 317
[175][TOP]
>UniRef100_Q87V72 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. tomato RepID=Q87V72_PSESM
Length = 281
Score = 70.1 bits (170), Expect = 1e-10
Identities = 35/85 (41%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++A+G + T+MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LA+ NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAVWNNLQL 279
[176][TOP]
>UniRef100_Q0KF23 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha H16
RepID=Q0KF23_RALEH
Length = 276
Score = 70.1 bits (170), Expect = 1e-10
Identities = 33/85 (38%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY +R + C ++P + LE D+ E+++A+G+ + T +C+++LA
Sbjct: 192 VPGIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + AI + L L
Sbjct: 252 GVPGLHFYTLNAAGATKAIWQRLKL 276
[177][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 70.1 bits (170), Expect = 1e-10
Identities = 35/85 (41%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C ++P I LE D+ E+++A+G+ + T MC ++L
Sbjct: 192 VPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN S AI + LGL
Sbjct: 252 GAPGLHFYTLNAAGSTRAIWQRLGL 276
[178][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 70.1 bits (170), Expect = 1e-10
Identities = 35/85 (41%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C ++P I LE D+ E+++A+G+ + T MC ++L
Sbjct: 192 VPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN S AI + LGL
Sbjct: 252 GAPGLHFYTLNAAGSTRAIWQRLGL 276
[179][TOP]
>UniRef100_B1J2Y7 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida W619
RepID=B1J2Y7_PSEPW
Length = 281
Score = 70.1 bits (170), Expect = 1e-10
Identities = 36/85 (42%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + T MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN +++LAI NL L
Sbjct: 255 GAPGLHFYTLNQAEASLAIWNNLKL 279
[180][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 70.1 bits (170), Expect = 1e-10
Identities = 37/94 (39%), Positives = 62/94 (65%), Gaps = 3/94 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGF--IRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL 402
+PGI+PI N + +R F K+P EI+ L+ K++ EA++A+GI T+MC+++
Sbjct: 228 IPGILPIQNLQTVRNLRKMNFA-VKVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELF 286
Query: 401 AHG-FKTLHLYTLNLEKSALAILKNLGLIEETSI 303
A G + +HLYTLN+EK ++IL+NL + +E +
Sbjct: 287 ASGKVQGIHLYTLNIEKPVMSILENLKISKEPEL 320
[181][TOP]
>UniRef100_Q6J6A1 Methylenetetrahydrofolate reductase n=1 Tax=Collimonas fungivorans
RepID=Q6J6A1_9BURK
Length = 284
Score = 69.7 bits (169), Expect = 2e-10
Identities = 32/85 (37%), Positives = 52/85 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+ GIMPI NY +R + C T+IP I L D+ ++++A+G+ + T++C+++LA
Sbjct: 200 IAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDSIRAFGLDVVTQLCERLLAG 259
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +AI + L L
Sbjct: 260 GAPGLHFYTLNQSPATIAIWQRLKL 284
[182][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 69.7 bits (169), Expect = 2e-10
Identities = 32/83 (38%), Positives = 50/83 (60%)
Frame = -1
Query: 569 GIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF 390
GIMPI NY R + C +IP I LE D++++++A+GI + T++C+ +L G
Sbjct: 196 GIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQDSIRAFGIDVVTQLCQTLLESGA 255
Query: 389 KTLHLYTLNLEKSALAILKNLGL 321
+H YT+N + L I +NLGL
Sbjct: 256 PGIHFYTMNQTQPTLQICRNLGL 278
[183][TOP]
>UniRef100_A0Y9Q7 Methylenetetrahydrofolate reductase n=1 Tax=marine gamma
proteobacterium HTCC2143 RepID=A0Y9Q7_9GAMM
Length = 276
Score = 69.7 bits (169), Expect = 2e-10
Identities = 33/84 (39%), Positives = 50/84 (59%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI NY R + C +IP I LE ++ E+V+ +GI + T++C+++LA G
Sbjct: 193 PGIMPITNYHNLARFSKSCGAEIPRWICQRLESFGNDSESVQEFGIEVVTQLCQRLLAEG 252
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
+H YT+N + I KNLG+
Sbjct: 253 APGIHFYTMNQVEPNRQIWKNLGI 276
[184][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 69.7 bits (169), Expect = 2e-10
Identities = 36/87 (41%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N++ F + +P+ AL P++ ++E V+ G L +MCK IL +
Sbjct: 213 IPGIMPIQNWEKFEKWVQRENIIVPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDN 272
Query: 395 ---GFKTLHLYTLNLEKSALAILKNLG 324
G K LH+YTLNLEK A +L+ LG
Sbjct: 273 KEAGIKGLHIYTLNLEKGARMLLRELG 299
[185][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 69.7 bits (169), Expect = 2e-10
Identities = 34/91 (37%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI++YK R+T ++P I++ LE ++ +++AVK G+ + T + +KI
Sbjct: 223 IPGLMPIHSYKILTRVTKLSHVQVPPHILSKLEAVRHDDDAVKRIGVDVITNLVDGIRKI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEE 312
GF+ H YTLNLEK+ I++ GLI +
Sbjct: 283 PNPGFRGFHFYTLNLEKTVSFIIERCGLIPD 313
[186][TOP]
>UniRef100_Q88D51 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida
KT2440 RepID=Q88D51_PSEPK
Length = 295
Score = 69.3 bits (168), Expect = 2e-10
Identities = 36/85 (42%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + T MC+++L
Sbjct: 209 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQG 268
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NL L
Sbjct: 269 GAPGLHFYTLNQAEPSLAIWNNLKL 293
[187][TOP]
>UniRef100_Q1R0K0 Methylenetetrahydrofolate reductase n=1 Tax=Chromohalobacter
salexigens DSM 3043 RepID=Q1R0K0_CHRSD
Length = 282
Score = 69.3 bits (168), Expect = 2e-10
Identities = 35/83 (42%), Positives = 47/83 (56%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C IP I LE D+ E+++A+G + T +C+++L
Sbjct: 196 VPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAFGSEVVTRLCQRLLDG 255
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN AL +L NL
Sbjct: 256 GAPGLHFYTLNQATPALRVLDNL 278
[188][TOP]
>UniRef100_Q1I3W4 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas entomophila
L48 RepID=Q1I3W4_PSEE4
Length = 281
Score = 69.3 bits (168), Expect = 2e-10
Identities = 36/85 (42%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + T MC+++L
Sbjct: 195 VPGIMPITNYNKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAIWNNLKL 279
[189][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 69.3 bits (168), Expect = 2e-10
Identities = 31/83 (37%), Positives = 42/83 (50%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+ + C IP E++ E DN E K GI T C ++ H
Sbjct: 205 IPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYADNPEETKKIGIEFATLQCMDLIKH 264
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G K LH YTLN + + I +N+
Sbjct: 265 GVKGLHFYTLNKSDATIKIYENI 287
[190][TOP]
>UniRef100_B0KM01 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida GB-1
RepID=B0KM01_PSEPG
Length = 281
Score = 69.3 bits (168), Expect = 2e-10
Identities = 36/85 (42%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + T MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAIWNNLKL 279
[191][TOP]
>UniRef100_A5WA10 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida F1
RepID=A5WA10_PSEP1
Length = 281
Score = 69.3 bits (168), Expect = 2e-10
Identities = 36/85 (42%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + T MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAIWNNLKL 279
[192][TOP]
>UniRef100_A4FAF8 Methylenetetrahydrofolate reductase n=1 Tax=Saccharopolyspora
erythraea NRRL 2338 RepID=A4FAF8_SACEN
Length = 294
Score = 69.3 bits (168), Expect = 2e-10
Identities = 31/86 (36%), Positives = 50/86 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI + + +P ++ LEP+ D+ A +A G+ L TE+C++++A
Sbjct: 205 LPGIMPITTPRVLRKFGELSGAPVPPAVLERLEPLADDAAAFRAEGVVLATELCERLIAE 264
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLI 318
G LH YTLN K+ ++ NLGL+
Sbjct: 265 GVPALHFYTLNRSKATREVVSNLGLL 290
[193][TOP]
>UniRef100_C7RKF7 5,10-methylenetetrahydrofolate reductase n=1 Tax=Candidatus
Accumulibacter phosphatis clade IIA str. UW-1
RepID=C7RKF7_9PROT
Length = 279
Score = 69.3 bits (168), Expect = 2e-10
Identities = 33/85 (38%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI++Y R + C +IP I LE D+ +++A+G+ + T++C+K+LA
Sbjct: 194 VPGIMPISSYSSLARFSDNCGAEIPRWIRKKLESYGDDSASIRAFGLDVVTQLCEKLLAS 253
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + + LGL
Sbjct: 254 GAPGLHFYTLNQASLTSTLWQRLGL 278
[194][TOP]
>UniRef100_C7QA95 5,10-methylenetetrahydrofolate reductase n=1 Tax=Catenulispora
acidiphila DSM 44928 RepID=C7QA95_CATAD
Length = 315
Score = 69.3 bits (168), Expect = 2e-10
Identities = 32/85 (37%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PG+MP+ N R+TG PA++ +L ++ ++ AV+A G+ T MC+++LA
Sbjct: 217 LPGVMPVTNVAQIKRITGLTGQAFPADLERSLMAVEGDKAAVRAVGVDWTTRMCERLLAE 276
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH TLN+ + L I +NLGL
Sbjct: 277 GVPGLHFITLNMSTATLEIYRNLGL 301
[195][TOP]
>UniRef100_C7HXI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Thiomonas
intermedia K12 RepID=C7HXI3_THIIN
Length = 285
Score = 69.3 bits (168), Expect = 2e-10
Identities = 32/84 (38%), Positives = 52/84 (61%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N +R + C +IP I L+ D+ E+++A+G + + +C++++A
Sbjct: 201 VPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRESIRAFGREVVSSLCEELIAS 260
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLN ++ LA+L +LG
Sbjct: 261 GAPGLHFYTLNQAEATLAVLDDLG 284
[196][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 69.3 bits (168), Expect = 2e-10
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Frame = -1
Query: 569 GIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG- 393
G++PI Y GF+RM CKT +P+++ +E +K+N + +K YG+ +M + I G
Sbjct: 222 GLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGL 281
Query: 392 -FKTLHLYTLNLEKSALAILKNLGLIEE 312
+ LH YTLN +LK L + E
Sbjct: 282 DYHHLHFYTLNNSAQTFKVLKRLNALVE 309
[197][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 69.3 bits (168), Expect = 2e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 3/91 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI++YK R+T KIP I+A L+ +K +++AVK G+ + E+ KK+
Sbjct: 223 IPGLMPIHSYKILTRVTKLSHVKIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKL 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEE 312
G + H YTLNLEK+ IL+ LI +
Sbjct: 283 PTPGLRGFHFYTLNLEKTVSFILERCKLIPD 313
[198][TOP]
>UniRef100_Q3K5D6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas fluorescens
Pf0-1 RepID=Q3K5D6_PSEPF
Length = 281
Score = 68.9 bits (167), Expect = 3e-10
Identities = 34/85 (40%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ ++++ +G + TEMC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFGEQVVTEMCERLLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH Y++N + +LAI NL L
Sbjct: 255 GAPGLHFYSMNQAEPSLAIWNNLKL 279
[199][TOP]
>UniRef100_Q21NJ7 Methylenetetrahydrofolate reductase n=1 Tax=Saccharophagus
degradans 2-40 RepID=Q21NJ7_SACD2
Length = 297
Score = 68.9 bits (167), Expect = 3e-10
Identities = 34/84 (40%), Positives = 48/84 (57%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PGIMPI NY+ R + C IP + +E DN+EA+ ++GI +E+C +L G
Sbjct: 196 PGIMPILNYRNLARFSDSCGADIPRWMRKRMESFGDNQEALISFGIDWISELCDTLLDAG 255
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
LH YT+N + I+KNLGL
Sbjct: 256 APGLHFYTMNQTEPTATIIKNLGL 279
[200][TOP]
>UniRef100_C9YE70 5,10-methylenetetrahydrofolate reductase n=1 Tax=Curvibacter
putative symbiont of Hydra magnipapillata
RepID=C9YE70_9BURK
Length = 305
Score = 68.9 bits (167), Expect = 3e-10
Identities = 33/85 (38%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI + +R + C +IP I L+ D ++KA+G+ + T++C+++ A
Sbjct: 219 VPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSYGDEVASIKAFGLEVVTDLCEQLRAG 278
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YT+N LA+ KNLGL
Sbjct: 279 GAPALHFYTMNQSAPTLALCKNLGL 303
[201][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 68.9 bits (167), Expect = 3e-10
Identities = 41/109 (37%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA- 399
+PG+MPI+ YK R+T IP IM+ +E ++ ++E VK G+ + +E+ +I A
Sbjct: 223 IPGLMPIHGYKILTRVTKLSAAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKAL 282
Query: 398 --HGFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDG 258
G + H YTLNLEKS IL++ LI P N A EDG
Sbjct: 283 PNPGQRGYHFYTLNLEKSVTLILESCDLIP--------PCNDDSAVEDG 323
[202][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 68.9 bits (167), Expect = 3e-10
Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-- 402
+P IMPI +Y RMT C +P+ +M L K ++EA+K G+ +M KKI+
Sbjct: 219 IPAIMPIQSYGSLKRMTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDN 278
Query: 401 ----AHGFKTLHLYTLNLEKSALAILKNLGLI 318
HGF H TLNLE+S ILKN GL+
Sbjct: 279 VQGRVHGF---HFCTLNLERSVALILKNSGLL 307
[203][TOP]
>UniRef100_A3TKC9 Methylenetetrahydrofolate reductase n=1 Tax=Janibacter sp. HTCC2649
RepID=A3TKC9_9MICO
Length = 295
Score = 68.6 bits (166), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%)
Frame = -1
Query: 572 PGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG 393
PG+MP+ N K RMT T +PA ++ L+ + ++ AV++ G+ + TE+ +++LA G
Sbjct: 207 PGLMPVTNLKQITRMTELMGTPLPAAVVDRLQAVSEDPAAVRSVGVEIATEIAQRMLAEG 266
Query: 392 FKTLHLYTLNLEKSALAILKNLGL 321
LH T+N + L + +NLGL
Sbjct: 267 APGLHFITMNRSTATLEVYENLGL 290
[204][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 68.6 bits (166), Expect = 3e-10
Identities = 34/84 (40%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI Y F R+T C TK+P+ + A L PIK++++ VK YG+ + ++
Sbjct: 208 IPGIMPIQTYATFARLTKLCGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIHRLRNE 267
Query: 395 -GFKTLHLYTLNLEKSALAILKNL 327
G + H TLNLEKS +L+ L
Sbjct: 268 GGIQGFHFCTLNLEKSVQRVLEEL 291
[205][TOP]
>UniRef100_Q4K4H6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas fluorescens
Pf-5 RepID=Q4K4H6_PSEF5
Length = 288
Score = 68.2 bits (165), Expect = 4e-10
Identities = 35/85 (41%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ +++A+G + ++MC+++L
Sbjct: 202 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFGEQVISDMCERLLQG 261
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN +LAI NL L
Sbjct: 262 GAPGLHFYTLNQADPSLAIWNNLQL 286
[206][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 68.2 bits (165), Expect = 4e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+ + C IP +++ E DN E K GI T+ C+ +L +
Sbjct: 205 IPGIMPITNFNQIRKFASLCGATIPEDVVKLFEKYADNPEETKKIGIEFATKQCEDLLKN 264
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G K LH YTLN + + I N+
Sbjct: 265 GVKGLHFYTLNKSDATIKIYNNI 287
[207][TOP]
>UniRef100_B1Y645 Methylenetetrahydrofolate reductase n=1 Tax=Leptothrix cholodnii
SP-6 RepID=B1Y645_LEPCP
Length = 279
Score = 68.2 bits (165), Expect = 4e-10
Identities = 33/85 (38%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N G IR +IP I L+ D+ ++KA+G+ + T++C+++ A
Sbjct: 195 VPGIMPITNSSGIIRFADGSGAEIPRWIRLRLQSYGDDSASIKAFGLDVVTDLCERLRAG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YT+N + L I + LGL
Sbjct: 255 GVPALHFYTMNSSAAVLQICERLGL 279
[208][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 68.2 bits (165), Expect = 4e-10
Identities = 31/83 (37%), Positives = 42/83 (50%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+ + C IP E++ E DN E K GI T C ++ H
Sbjct: 205 IPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYADNPEETKKIGIEFATLQCIDLIKH 264
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G K LH YTLN + + I +N+
Sbjct: 265 GAKGLHFYTLNKSDATIKIYENI 287
[209][TOP]
>UniRef100_A4A9E4 Methylenetetrahydrofolate reductase n=1 Tax=Congregibacter
litoralis KT71 RepID=A4A9E4_9GAMM
Length = 278
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/83 (38%), Positives = 49/83 (59%)
Frame = -1
Query: 569 GIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF 390
GIMPI NY R + C +IP I LE D++E+++A+GI + T++C+ +L
Sbjct: 196 GIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQESIRAFGIDVVTQLCQTLLESDA 255
Query: 389 KTLHLYTLNLEKSALAILKNLGL 321
+H YT+N + L I +NLGL
Sbjct: 256 PGIHFYTMNQAQPTLQICRNLGL 278
[210][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 68.2 bits (165), Expect = 4e-10
Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI +Y R+T +P EI+A +E K ++EAVK G+ + +E+ K I
Sbjct: 223 IPGLMPIQSYSRLTRITKLSHACVPPEILARIEKCKMDDEAVKRVGVDVVSELVDEIKTI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEETSIP 300
G + LH +TLNLEKS IL+ LI +S P
Sbjct: 283 SCPGPRGLHFFTLNLEKSVSFILERCNLIPSSSEP 317
[211][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 68.2 bits (165), Expect = 4e-10
Identities = 39/115 (33%), Positives = 64/115 (55%), Gaps = 9/115 (7%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PG+MPI +YK +R T ++PAE++A L+ +K ++E VK G+ + EM + I A
Sbjct: 226 IPGLMPIQSYKILLRTTKLSHARLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKAR 285
Query: 395 G---FKTLHLYTLNLEKSALAILKNLGLI------EETSIPRTRPANAIQAKEDG 258
+ H YTLNLEK+ ++++ LI +E I T PA ++ +G
Sbjct: 286 PETCRRGFHFYTLNLEKAVSHVVEDTHLIPTTIMDDEEIIVETTPAINLEPPPNG 340
[212][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 67.8 bits (164), Expect = 6e-10
Identities = 30/83 (36%), Positives = 48/83 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N++ + C IP +++ LE ++++ E V GI TE C+ +L +
Sbjct: 206 IPGIMPITNFRQIEKFAVMCGATIPKDLVEKLEKVENSPEEVAKIGIDYATEQCEDLLKN 265
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G K LH YTLN K+ + I + +
Sbjct: 266 GVKGLHFYTLNKSKATVEIYRRI 288
[213][TOP]
>UniRef100_A1K2Z6 Methylenetetrahydrofolate reductase n=1 Tax=Azoarcus sp. BH72
RepID=A1K2Z6_AZOSB
Length = 277
Score = 67.8 bits (164), Expect = 6e-10
Identities = 32/85 (37%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI ++ R + C +IP + E D+ +A++A+G+ + TE+C+K+LA
Sbjct: 192 VPGIMPIGSFSKLARFSDACGAEIPRWMRRKFESYGDDADAIRAFGLDVVTELCEKLLAA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH Y++N I K LGL
Sbjct: 252 GVPGLHFYSMNQSALTTEICKRLGL 276
[214][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 67.8 bits (164), Expect = 6e-10
Identities = 34/85 (40%), Positives = 48/85 (56%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP I LE D+ E+++ +G + T+MC+ ++ +
Sbjct: 193 VPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVESIQKFGEEVVTQMCEDLVEN 252
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
LH YTLN + I KNLGL
Sbjct: 253 DVPGLHFYTLNQADPCINIWKNLGL 277
[215][TOP]
>UniRef100_C5A8X3 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia glumae
BGR1 RepID=C5A8X3_BURGB
Length = 276
Score = 67.8 bits (164), Expect = 6e-10
Identities = 29/84 (34%), Positives = 49/84 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P + LE D++E+++A+G + T MC++++
Sbjct: 192 VPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDKESIRAFGADVVTAMCERLIRE 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLN + + + LG
Sbjct: 252 GAPGLHFYTLNAATATKVVCERLG 275
[216][TOP]
>UniRef100_Q2STU2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis E264 RepID=Q2STU2_BURTA
Length = 276
Score = 67.4 bits (163), Expect = 7e-10
Identities = 30/85 (35%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P I LE D++++++A+G + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADVVTGLCRRLIDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + A+ + LGL
Sbjct: 252 GVPGLHFYTLNGAAATKAVCERLGL 276
[217][TOP]
>UniRef100_B0T509 Methylenetetrahydrofolate reductase n=1 Tax=Caulobacter sp. K31
RepID=B0T509_CAUSK
Length = 320
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/99 (32%), Positives = 52/99 (52%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPG+MP+ N+KG ++M+ C T +P + + + D+ + + + EMC K+
Sbjct: 220 VPGVMPVTNFKGLVKMSKACGTAVPDWLTKLFDGLDDDADTRRLIACSVAAEMCAKLQEQ 279
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANA 279
GF H YTLN AI + LG+ E ++P P +A
Sbjct: 280 GFSDFHFYTLNRADLVYAICRVLGVRE--TVPAPSPISA 316
[218][TOP]
>UniRef100_C3XBX2 Methylenetetrahydrofolate reductase n=1 Tax=Oxalobacter formigenes
OXCC13 RepID=C3XBX2_OXAFO
Length = 294
Score = 67.4 bits (163), Expect = 7e-10
Identities = 35/101 (34%), Positives = 55/101 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+ GIMPI N+K + + C +IP I LE D+ +++A+G+ + TE+C+++LA
Sbjct: 193 IAGIMPITNFKQLAQFSDMCGAEIPRWIRLRLESYGDDLASIRAFGLDVVTELCEQLLAG 252
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEETSIPRTRPANAIQ 273
G LH Y+LN + I L L E I + A A+Q
Sbjct: 253 GAPGLHFYSLNKAATTREIWHRLKLDERKEIGSDKKAEAVQ 293
[219][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 67.4 bits (163), Expect = 7e-10
Identities = 29/79 (36%), Positives = 43/79 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+K + C IP ++ +EP++D E V G+ + C+ +L +
Sbjct: 205 IPGIMPITNFKQIKKFASMCGATIPQSLIEKMEPVEDKPEEVAKIGVEFAVKQCEDLLRN 264
Query: 395 GFKTLHLYTLNLEKSALAI 339
G LH YTLN K+ L I
Sbjct: 265 GVPGLHFYTLNRSKATLNI 283
[220][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 67.4 bits (163), Expect = 7e-10
Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI +Y R+T ++P E+++ +E K ++EAVK G+ + +E+ K I
Sbjct: 223 IPGLMPIQSYPRLTRITKLSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G + LH YTLNLEKS IL+ LI +S
Sbjct: 283 PGTGPRGLHFYTLNLEKSVSFILERCNLIPPSS 315
[221][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 67.4 bits (163), Expect = 7e-10
Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
+PG+MPI +Y R+T ++P E+++ +E K ++EAVK G+ + +E+ K I
Sbjct: 223 IPGLMPIQSYPRLTRITKLSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTI 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G + LH YTLNLEKS IL+ LI +S
Sbjct: 283 PGTGPRGLHFYTLNLEKSVSFILERCNLIPPSS 315
[222][TOP]
>UniRef100_UPI00016A554F 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
ubonensis Bu RepID=UPI00016A554F
Length = 276
Score = 67.0 bits (162), Expect = 1e-09
Identities = 31/85 (36%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P I LE D+ +A++A+G + T +C+++L
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADVVTGLCQRLLDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + I + LG+
Sbjct: 252 GVPGLHFYTLNSAAATKTICERLGV 276
[223][TOP]
>UniRef100_C3K3G7 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas fluorescens
SBW25 RepID=C3K3G7_PSEFS
Length = 281
Score = 67.0 bits (162), Expect = 1e-09
Identities = 34/85 (40%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP + LE D+ ++++A+G + + MC+++L
Sbjct: 195 VPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFGEQVISTMCEELLQG 254
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + +LAI NL L
Sbjct: 255 GAPGLHFYTLNQAEPSLAIWNNLKL 279
[224][TOP]
>UniRef100_C5V644 Methylenetetrahydrofolate reductase n=1 Tax=Gallionella ferruginea
ES-2 RepID=C5V644_9PROT
Length = 275
Score = 67.0 bits (162), Expect = 1e-09
Identities = 34/83 (40%), Positives = 48/83 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI Y R + C +IP + +E D+ E+V+A+G + T MC+K+LA
Sbjct: 192 VPGIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRDIVTAMCEKLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G LH YTLN +AI++ L
Sbjct: 252 GAPGLHFYTLNQAAPCMAIVERL 274
[225][TOP]
>UniRef100_C0DWJ7 Methylenetetrahydrofolate reductase n=1 Tax=Eikenella corrodens
ATCC 23834 RepID=C0DWJ7_EIKCO
Length = 277
Score = 67.0 bits (162), Expect = 1e-09
Identities = 33/84 (39%), Positives = 46/84 (54%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ R C +IP + L+ D+ ++KA G+ + TEMC ++L H
Sbjct: 193 VPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLDVVTEMCGRLLRH 252
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLN + I + LG
Sbjct: 253 GAPGLHFYTLNQAGLSSTICQRLG 276
[226][TOP]
>UniRef100_B5WH86 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia sp. H160
RepID=B5WH86_9BURK
Length = 276
Score = 67.0 bits (162), Expect = 1e-09
Identities = 30/85 (35%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P I LE D+ E+++A+G+ + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLEVVTNLCQRLVDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
LH YTLN + AI + LG+
Sbjct: 252 KVPGLHFYTLNTAAATKAICERLGV 276
[227][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 67.0 bits (162), Expect = 1e-09
Identities = 33/89 (37%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKI 405
VPG+MPI++YK R+T KIP +++ LE +K +++AVK G+ + +++ + +
Sbjct: 223 VPGLMPIHSYKILTRVTKLSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIISDLVHGIRDL 282
Query: 404 LAHGFKTLHLYTLNLEKSALAILKNLGLI 318
++ G + H YTLNLEK+ IL+ LI
Sbjct: 283 VSPGLRGFHFYTLNLEKTVSFILERCELI 311
[228][TOP]
>UniRef100_B1JTJ6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia MC0-3 RepID=B1JTJ6_BURCC
Length = 276
Score = 66.6 bits (161), Expect = 1e-09
Identities = 29/85 (34%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P + LE D+ E+++A+G + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTSLCQRLIDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLNL + I + L +
Sbjct: 252 GVPGLHFYTLNLATATRTICERLAV 276
[229][TOP]
>UniRef100_A0K3F1 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia
cenocepacia RepID=A0K3F1_BURCH
Length = 276
Score = 66.6 bits (161), Expect = 1e-09
Identities = 29/85 (34%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P + LE D+ E+++A+G + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTNLCQRLIDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLNL + I + L +
Sbjct: 252 GVPGLHFYTLNLATATRTICERLAV 276
[230][TOP]
>UniRef100_B5HCL5 Methylenetetrahydrofolate reductase n=1 Tax=Streptomyces
pristinaespiralis ATCC 25486 RepID=B5HCL5_STRPR
Length = 305
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/89 (37%), Positives = 48/89 (53%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+P IMP+ + K R PAE+ + +KD+ AV++ GI TE C ++LA
Sbjct: 217 IPEIMPVTSVKQIERFATLSNAHFPAELKERILAVKDDPAAVRSIGIEFATEFCARLLAE 276
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIEET 309
G LH TLN + L I +NLGL E++
Sbjct: 277 GVPGLHFITLNNSTATLEIYENLGLHEQS 305
[231][TOP]
>UniRef100_UPI0000E87FC4 metF; 5,10-methylenetetrahydrofolate reductase oxidoreductase
protein n=1 Tax=Methylophilales bacterium HTCC2181
RepID=UPI0000E87FC4
Length = 277
Score = 66.2 bits (160), Expect = 2e-09
Identities = 32/83 (38%), Positives = 50/83 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N K R + C ++IP + LE D+ E++++YGI + TE+C+ ++ +
Sbjct: 193 VPGIMPIYNIKQLSRFSANCGSEIPRWLKMKLEDYGDDLESLRSYGIDVITELCETLIQY 252
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G ++H YTLN I+ NL
Sbjct: 253 GVPSVHFYTLNQSGIITKIINNL 275
[232][TOP]
>UniRef100_Q8PP97 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas axonopodis
pv. citri RepID=Q8PP97_XANAC
Length = 275
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAALCERLIAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GAPALHFYTLNLAKPTTQVLQLLG 274
[233][TOP]
>UniRef100_Q4UQY4 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas campestris
pv. campestris RepID=Q4UQY4_XANC8
Length = 275
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAGLCERLIAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GVPALHFYTLNLAKPTTQVLQLLG 274
[234][TOP]
>UniRef100_Q3BXE0 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. vesicatoria str. 85-10 RepID=Q3BXE0_XANC5
Length = 275
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAALCQRLIAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GAPALHFYTLNLAKPTTQVLQLLG 274
[235][TOP]
>UniRef100_Q2NZD1 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas oryzae pv.
oryzae RepID=Q2NZD1_XANOM
Length = 275
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVVAALCERLIAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GAPALHFYTLNLAKPTTQVLQLLG 274
[236][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 66.2 bits (160), Expect = 2e-09
Identities = 32/83 (38%), Positives = 44/83 (53%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY+ R T C +P + LE +KDN EA+ G+ T C ++L+
Sbjct: 204 VPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKDNPEAMAQLGVAHATVQCMELLSR 263
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
G +H YTLN + I+ L
Sbjct: 264 GVPGIHFYTLNKSPATRMIVSAL 286
[237][TOP]
>UniRef100_B4U6B3 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenobaculum sp.
Y04AAS1 RepID=B4U6B3_HYDS0
Length = 287
Score = 66.2 bits (160), Expect = 2e-09
Identities = 34/85 (40%), Positives = 47/85 (55%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N K + C IP+ I ALE + NEE V G+ + C+ ++ +
Sbjct: 205 IPGIMPITNIKQISKFASMCGATIPSYITDALENL--NEEDVVKKGVEIAINQCEDLIKN 262
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G K +H YTLN K+ L ILK + L
Sbjct: 263 GIKHIHFYTLNKSKATLQILKAIKL 287
[238][TOP]
>UniRef100_B2SPM2 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae pv.
oryzae PXO99A RepID=B2SPM2_XANOP
Length = 275
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVVAALCERLMAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GAPALHFYTLNLAKPTTQVLQLLG 274
[239][TOP]
>UniRef100_B0RV90 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. campestris str. B100 RepID=B0RV90_XANCB
Length = 285
Score = 66.2 bits (160), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 201 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAEVVAGLCERLIAG 260
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 261 GVPALHFYTLNLAKPTTQVLQLLG 284
[240][TOP]
>UniRef100_C4KD22 Methylenetetrahydrofolate reductase n=1 Tax=Thauera sp. MZ1T
RepID=C4KD22_THASP
Length = 277
Score = 66.2 bits (160), Expect = 2e-09
Identities = 30/85 (35%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI ++ R + C +IP + E D+ +A++A+G+ + T +C+K+LA
Sbjct: 191 VPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVVTRLCEKLLAA 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH Y++N+ I + LGL
Sbjct: 251 GAPGLHFYSMNMAGPTTEICRRLGL 275
[241][TOP]
>UniRef100_UPI0001695145 5,10-methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae
pv. oryzicola BLS256 RepID=UPI0001695145
Length = 275
Score = 65.9 bits (159), Expect = 2e-09
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI+N+ R + C +IP I ++ D+ +AV+A+G + +C++++A
Sbjct: 191 IPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVVAALCERLMAG 250
Query: 395 GFKTLHLYTLNLEKSALAILKNLG 324
G LH YTLNL K +L+ LG
Sbjct: 251 GAPALHFYTLNLAKPTTQVLQLLG 274
[242][TOP]
>UniRef100_Q3SFY6 Methylenetetrahydrofolate reductase n=1 Tax=Thiobacillus
denitrificans ATCC 25259 RepID=Q3SFY6_THIDA
Length = 276
Score = 65.9 bits (159), Expect = 2e-09
Identities = 32/85 (37%), Positives = 49/85 (57%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI NY R + C +IP + LE D+ +++A+G+ + T++C ++LA
Sbjct: 192 VPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLTSIRAFGLDVVTDLCDRLLAG 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YT+N + I + LGL
Sbjct: 252 GAPGLHFYTMNQAGPSTTIWQRLGL 276
[243][TOP]
>UniRef100_B2JIP2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia phymatum
STM815 RepID=B2JIP2_BURP8
Length = 276
Score = 65.9 bits (159), Expect = 2e-09
Identities = 29/85 (34%), Positives = 51/85 (60%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P + LE D+ E+++A+G+ + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDVVTNLCRRLVDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
LH YTLN ++ AI + LG+
Sbjct: 252 KVPGLHFYTLNGAAASKAICERLGV 276
[244][TOP]
>UniRef100_A1WFN0 Methylenetetrahydrofolate reductase n=1 Tax=Verminephrobacter
eiseniae EF01-2 RepID=A1WFN0_VEREI
Length = 283
Score = 65.9 bits (159), Expect = 2e-09
Identities = 30/85 (35%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI++ +R + C +IP I L+ D+ ++KA+G+ + T++C ++ +
Sbjct: 199 VPGIMPISSSTQLLRFSDACGAEIPRWIRLRLQAFGDDSASIKAFGLDVVTDLCDRLRSA 258
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + L I + LG+
Sbjct: 259 GVPALHFYTLNQSTATLEICRRLGI 283
[245][TOP]
>UniRef100_C6MEH9 Methylenetetrahydrofolate reductase n=1 Tax=Nitrosomonas sp. AL212
RepID=C6MEH9_9PROT
Length = 286
Score = 65.9 bits (159), Expect = 2e-09
Identities = 32/87 (36%), Positives = 49/87 (56%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPIN + +R + C +IP I LE D+ +++A+G+ + T++C+++L
Sbjct: 197 VPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQAFGLDVVTDLCERLLKA 256
Query: 395 GFKTLHLYTLNLEKSALAILKNLGLIE 315
G LH YTLN I + L L E
Sbjct: 257 GAPGLHFYTLNSASLTSIIWQRLNLKE 283
[246][TOP]
>UniRef100_A8V3W7 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8V3W7_9AQUI
Length = 230
Score = 65.9 bits (159), Expect = 2e-09
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+K + C IP ++ LE +D E V+ GI E C+ +L H
Sbjct: 143 IPGIMPITNFKQIRKFALMCGATIPEYLVKKLEKYQDIPEEVEKIGIEYAVEQCEDLLKH 202
Query: 395 GFKTLHLYTLNLEKSALAILKNL 327
K LH YTLN K+ L I +
Sbjct: 203 NVKGLHFYTLNKSKATLQIYNKI 225
[247][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 65.9 bits (159), Expect = 2e-09
Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA- 399
+PG+MPI+ YK R+T IP IM+ +E ++ ++E VK G+ + +E+ +I +
Sbjct: 223 IPGLMPIHGYKILTRVTKLSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIVNQIKSL 282
Query: 398 --HGFKTLHLYTLNLEKSALAILKNLGLIEETS 306
G + H YTLNLEKS IL+ LI +S
Sbjct: 283 PNPGHRGYHFYTLNLEKSVTLILERCDLIPPSS 315
[248][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 65.9 bits (159), Expect = 2e-09
Identities = 30/79 (37%), Positives = 40/79 (50%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
+PGIMPI N+K + C IP ++ LE ++D E VK GI C ++ H
Sbjct: 205 IPGIMPITNFKQIRKFASLCGATIPQSLIEKLEKVEDKPEEVKKIGIEFAINQCLDLIEH 264
Query: 395 GFKTLHLYTLNLEKSALAI 339
G LH YTLN + L I
Sbjct: 265 GVPGLHFYTLNKSDATLKI 283
[249][TOP]
>UniRef100_UPI00016A8C43 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei DM98 RepID=UPI00016A8C43
Length = 276
Score = 65.5 bits (158), Expect = 3e-09
Identities = 28/85 (32%), Positives = 50/85 (58%)
Frame = -1
Query: 575 VPGIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH 396
VPGIMPI N+ +R + C ++P + LE D++++++A+G + T +C++++
Sbjct: 192 VPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDA 251
Query: 395 GFKTLHLYTLNLEKSALAILKNLGL 321
G LH YTLN + + + LGL
Sbjct: 252 GVPGLHFYTLNGAAATKTVCERLGL 276
[250][TOP]
>UniRef100_A4G973 Methylenetetrahydrofolate reductase n=1 Tax=Herminiimonas
arsenicoxydans RepID=A4G973_HERAR
Length = 283
Score = 65.5 bits (158), Expect = 3e-09
Identities = 30/86 (34%), Positives = 50/86 (58%)
Frame = -1
Query: 569 GIMPINNYKGFIRMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF 390
G+MPI NY +R + C +IP I L D+ ++++A+G+ + T++C+++LA G
Sbjct: 198 GVMPITNYSQLMRFSDMCGAEIPRWIRLKLASYNDDTDSIRAFGLDVVTDLCERLLAGGA 257
Query: 389 KTLHLYTLNLEKSALAILKNLGLIEE 312
LH YTLN + AI L L ++
Sbjct: 258 PGLHFYTLNQAAATHAIWSRLNLSQK 283