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[1][TOP]
>UniRef100_B9RRL8 DNA topoisomerase n=1 Tax=Ricinus communis RepID=B9RRL8_RICCO
Length = 865
Score = 224 bits (570), Expect(2) = 7e-72
Identities = 105/134 (78%), Positives = 118/134 (88%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
P VLMVAEKPSIALSIAS LSHGQM ++KG TEVHEF+G FLG AH+KVTSVIGH+FSV
Sbjct: 4 PVVLMVAEKPSIALSIASALSHGQMSSKKGGTEVHEFDGMFLGFQAHYKVTSVIGHIFSV 63
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP KYQDW+A DP+DLFQA ++K ESNPK HI RHL+QEARGC LVLWLDCDREGENI
Sbjct: 64 DFPQKYQDWTANDPMDLFQAPIVKAESNPKVHIRRHLSQEARGCGHLVLWLDCDREGENI 123
Query: 432 CFEVIQSTGFNVND 473
CFEVI+ TGF++ND
Sbjct: 124 CFEVIECTGFHLND 137
Score = 71.6 bits (174), Expect(2) = 7e-72
Identities = 34/38 (89%), Positives = 37/38 (97%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSV EKD+LKA+DNLV+PNRDEALAVDARQEID
Sbjct: 143 YRARFSSVAEKDILKAMDNLVQPNRDEALAVDARQEID 180
[2][TOP]
>UniRef100_UPI000034EDEB DNA topoisomerase family protein n=1 Tax=Arabidopsis thaliana
RepID=UPI000034EDEB
Length = 865
Score = 223 bits (568), Expect(2) = 2e-71
Identities = 103/133 (77%), Positives = 118/133 (88%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
+VLMVAEKPSIALSIASVLSHGQM TR+GSTEVHEF+G F G AH++VTSVIGHVFSVD
Sbjct: 6 RVLMVAEKPSIALSIASVLSHGQMSTRRGSTEVHEFDGMFRGFKAHYRVTSVIGHVFSVD 65
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
FP KYQ+W+ DP DLF A ++K ESNPKAHICRHL+ EARGC ++VLWLDCDREGENIC
Sbjct: 66 FPEKYQNWATIDPQDLFDAPIIKKESNPKAHICRHLSNEARGCSYMVLWLDCDREGENIC 125
Query: 435 FEVIQSTGFNVND 473
FEVI+STGF++ D
Sbjct: 126 FEVIESTGFDMKD 138
Score = 70.9 bits (172), Expect(2) = 2e-71
Identities = 34/38 (89%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+ KA+DNLV PNRDEALAVDARQEID
Sbjct: 144 YRARFSSVTEKDISKAMDNLVEPNRDEALAVDARQEID 181
[3][TOP]
>UniRef100_Q56YZ6 DNA topoisomerase n=1 Tax=Arabidopsis thaliana RepID=Q56YZ6_ARATH
Length = 865
Score = 221 bits (562), Expect(2) = 9e-71
Identities = 103/133 (77%), Positives = 117/133 (87%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
+VLMVAEKPSIALSIASVLSHGQM TR GSTEVHEF+G F G AH++VTSVIGHVFSVD
Sbjct: 6 RVLMVAEKPSIALSIASVLSHGQMSTRGGSTEVHEFDGMFRGFKAHYRVTSVIGHVFSVD 65
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
FP KYQ+W+ DP DLF A ++K ESNPKAHICRHL+ EARGC ++VLWLDCDREGENIC
Sbjct: 66 FPEKYQNWATIDPQDLFGAPIIKKESNPKAHICRHLSNEARGCSYMVLWLDCDREGENIC 125
Query: 435 FEVIQSTGFNVND 473
FEVI+STGF++ D
Sbjct: 126 FEVIESTGFDMKD 138
Score = 70.9 bits (172), Expect(2) = 9e-71
Identities = 34/38 (89%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+ KA+DNLV PNRDEALAVDARQEID
Sbjct: 144 YRARFSSVTEKDISKAMDNLVEPNRDEALAVDARQEID 181
[4][TOP]
>UniRef100_Q9SKZ9 Putative DNA topoisomerase III beta n=1 Tax=Arabidopsis thaliana
RepID=Q9SKZ9_ARATH
Length = 836
Score = 210 bits (535), Expect(2) = 1e-67
Identities = 100/136 (73%), Positives = 114/136 (83%), Gaps = 7/136 (5%)
Frame = +3
Query: 87 VAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDFPGK 266
VAEKPSIALSIASVLSHGQM TR+GSTEVHEF+G F G AH++VTSVIGHVFSVDFP K
Sbjct: 40 VAEKPSIALSIASVLSHGQMSTRRGSTEVHEFDGMFRGFKAHYRVTSVIGHVFSVDFPEK 99
Query: 267 YQDWSATDPLDLFQAQVLKNESNPK-------AHICRHLNQEARGCRFLVLWLDCDREGE 425
YQ+W+ DP DLF A ++K ESNPK AHICRHL+ EARGC ++VLWLDCDREGE
Sbjct: 100 YQNWATIDPQDLFDAPIIKKESNPKVNIFKSQAHICRHLSNEARGCSYMVLWLDCDREGE 159
Query: 426 NICFEVIQSTGFNVND 473
NICFEVI+STGF++ D
Sbjct: 160 NICFEVIESTGFDMKD 175
Score = 70.9 bits (172), Expect(2) = 1e-67
Identities = 34/38 (89%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+ KA+DNLV PNRDEALAVDARQEID
Sbjct: 181 YRARFSSVTEKDISKAMDNLVEPNRDEALAVDARQEID 218
[5][TOP]
>UniRef100_C5X4M3 DNA topoisomerase n=1 Tax=Sorghum bicolor RepID=C5X4M3_SORBI
Length = 866
Score = 213 bits (543), Expect(2) = 4e-67
Identities = 104/135 (77%), Positives = 116/135 (85%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
MAPKVLMVAEKPSIALSIAS LS G+M TRKGST+VHEF+G F GS A+FKVTSVIGHV
Sbjct: 1 MAPKVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGTFQGSYANFKVTSVIGHVL 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
SVDFP YQ+W ATDPLDLF+A VL++E NPKAHI RHL QEARGC +L+LWLDCDREGE
Sbjct: 61 SVDFPPAYQNWEATDPLDLFEAPVLRSECNPKAHIRRHLAQEARGCTYLILWLDCDREGE 120
Query: 426 NICFEVIQSTGFNVN 470
NIC+EVI+ TG N
Sbjct: 121 NICYEVIECTGIPDN 135
Score = 66.2 bits (160), Expect(2) = 4e-67
Identities = 31/38 (81%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSSVTEKD+L A+DNLV PN+DEAL+VDARQEID
Sbjct: 140 FRARFSSVTEKDILTAMDNLVLPNKDEALSVDARQEID 177
[6][TOP]
>UniRef100_UPI0001983585 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001983585
Length = 944
Score = 206 bits (525), Expect(2) = 7e-66
Identities = 102/134 (76%), Positives = 112/134 (83%), Gaps = 2/134 (1%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG--STEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
+L VAEKPSIALSIAS LS G M TR+G STEVHEF G F GS A +KVTSVIGHVFSV
Sbjct: 82 ILQVAEKPSIALSIASALSGGHMSTRRGGSSTEVHEFNGTFRGSNAQYKVTSVIGHVFSV 141
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP KYQDW+ TDPLDLFQA +LK ESNPKAHI RHL+QEAR C LVLWLDCDREGENI
Sbjct: 142 DFPAKYQDWTVTDPLDLFQAPILKAESNPKAHIRRHLSQEARDCGHLVLWLDCDREGENI 201
Query: 432 CFEVIQSTGFNVND 473
CFEV++ TGF+ N+
Sbjct: 202 CFEVVECTGFHGNE 215
Score = 68.9 bits (167), Expect(2) = 7e-66
Identities = 33/38 (86%), Positives = 35/38 (92%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+LKA+DNLV PN DEA AVDARQEID
Sbjct: 221 YRARFSSVTEKDILKAMDNLVEPNEDEARAVDARQEID 258
[7][TOP]
>UniRef100_A7Q9K8 DNA topoisomerase n=1 Tax=Vitis vinifera RepID=A7Q9K8_VITVI
Length = 847
Score = 206 bits (523), Expect(2) = 1e-65
Identities = 102/132 (77%), Positives = 111/132 (84%), Gaps = 2/132 (1%)
Frame = +3
Query: 84 MVAEKPSIALSIASVLSHGQMFTRKG--STEVHEFEGKFLGSPAHFKVTSVIGHVFSVDF 257
MVAEKPSIALSIAS LS G M TR+G STEVHEF G F GS A +KVTSVIGHVFSVDF
Sbjct: 7 MVAEKPSIALSIASALSGGHMSTRRGGSSTEVHEFNGTFRGSNAQYKVTSVIGHVFSVDF 66
Query: 258 PGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICF 437
P KYQDW+ TDPLDLFQA +LK ESNPKAHI RHL+QEAR C LVLWLDCDREGENICF
Sbjct: 67 PAKYQDWTVTDPLDLFQAPILKAESNPKAHIRRHLSQEARDCGHLVLWLDCDREGENICF 126
Query: 438 EVIQSTGFNVND 473
EV++ TGF+ N+
Sbjct: 127 EVVECTGFHGNE 138
Score = 68.9 bits (167), Expect(2) = 1e-65
Identities = 33/38 (86%), Positives = 35/38 (92%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+LKA+DNLV PN DEA AVDARQEID
Sbjct: 144 YRARFSSVTEKDILKAMDNLVEPNEDEARAVDARQEID 181
[8][TOP]
>UniRef100_Q0J0S6 DNA topoisomerase n=1 Tax=Oryza sativa Japonica Group
RepID=Q0J0S6_ORYSJ
Length = 866
Score = 207 bits (527), Expect(2) = 6e-64
Identities = 102/137 (74%), Positives = 113/137 (82%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
MAP VLMVAEKPSIALSIAS LS G+M TRKGST+VHEF+G F GS A FKVTSVIGHV
Sbjct: 1 MAPTVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVL 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
SVDFP YQ+W TDP+DLF A VL++E NPKAHI RHL QEARGC +LVLWLDCDREGE
Sbjct: 61 SVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGE 120
Query: 426 NICFEVIQSTGFNVNDV 476
NIC+EVI TG ++V
Sbjct: 121 NICYEVIDCTGIPKSEV 137
Score = 61.6 bits (148), Expect(2) = 6e-64
Identities = 28/38 (73%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FSSVTEKD++ A++NLV P++DEALAVDARQEID
Sbjct: 142 FRAKFSSVTEKDIMDAMNNLVLPSKDEALAVDARQEID 179
[9][TOP]
>UniRef100_B8BD52 DNA topoisomerase n=1 Tax=Oryza sativa Indica Group
RepID=B8BD52_ORYSI
Length = 866
Score = 207 bits (527), Expect(2) = 6e-64
Identities = 102/137 (74%), Positives = 113/137 (82%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
MAP VLMVAEKPSIALSIAS LS G+M TRKGST+VHEF+G F GS A FKVTSVIGHV
Sbjct: 1 MAPTVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVL 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
SVDFP YQ+W TDP+DLF A VL++E NPKAHI RHL QEARGC +LVLWLDCDREGE
Sbjct: 61 SVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGE 120
Query: 426 NICFEVIQSTGFNVNDV 476
NIC+EVI TG ++V
Sbjct: 121 NICYEVIDCTGIPKSEV 137
Score = 61.6 bits (148), Expect(2) = 6e-64
Identities = 28/38 (73%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FSSVTEKD++ A++NLV P++DEALAVDARQEID
Sbjct: 142 FRAKFSSVTEKDIMDAMNNLVLPSKDEALAVDARQEID 179
[10][TOP]
>UniRef100_A9U3N3 DNA topoisomerase n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9U3N3_PHYPA
Length = 869
Score = 204 bits (519), Expect(2) = 3e-60
Identities = 93/129 (72%), Positives = 108/129 (83%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
MAP VLMVAEKPSIALSIA+ LSHG+M +R+ EVHEF+G F G+ FKVTSVIGHV
Sbjct: 1 MAPSVLMVAEKPSIALSIANFLSHGRMSSRRSYLEVHEFDGSFRGTSVRFKVTSVIGHVL 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DFP KYQ W TDP +LF+A +KNESNPKAH+C+HL QEARGC +LVLWLDCDREGE
Sbjct: 61 SIDFPPKYQSWDTTDPFELFEAPTIKNESNPKAHVCKHLQQEARGCDYLVLWLDCDREGE 120
Query: 426 NICFEVIQS 452
NICFEV++S
Sbjct: 121 NICFEVMES 129
Score = 52.4 bits (124), Expect(2) = 3e-60
Identities = 23/38 (60%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS+++EKDV A++ L PN+DE+L+VDARQEID
Sbjct: 143 FRAKFSAISEKDVRVAMNTLGEPNKDESLSVDARQEID 180
[11][TOP]
>UniRef100_B9IAB5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9IAB5_POPTR
Length = 837
Score = 190 bits (482), Expect(2) = 5e-59
Identities = 88/110 (80%), Positives = 95/110 (86%)
Frame = +3
Query: 144 MFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLK 323
M +RKG+TEVHEFEG F G A+FKVTSVIGHVFSVDFP KYQDW+ATDP DLFQA + K
Sbjct: 1 MHSRKGTTEVHEFEGMFNGFRAYFKVTSVIGHVFSVDFPAKYQDWAATDPADLFQAPIHK 60
Query: 324 NESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICFEVIQSTGFNVND 473
E+NPKAHICRHL+QEARGC LVLWLDCDREGENICFEVIQ TGF ND
Sbjct: 61 AEANPKAHICRHLSQEARGCNHLVLWLDCDREGENICFEVIQCTGFQAND 110
Score = 62.4 bits (150), Expect(2) = 5e-59
Identities = 31/38 (81%), Positives = 34/38 (89%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+LKA++ LV PN EALAVDARQEID
Sbjct: 116 YRARFSSVTEKDILKAMNCLVEPNEYEALAVDARQEID 153
[12][TOP]
>UniRef100_A8J6M3 DNA topoisomerase (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8J6M3_CHLRE
Length = 644
Score = 171 bits (432), Expect(2) = 7e-50
Identities = 76/129 (58%), Positives = 98/129 (75%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M+ VLMVAEKPS+A SIA +LS G++ +R+ + +VHE+EG+F G PA FK+TSVIGHV+
Sbjct: 1 MSLSVLMVAEKPSLAGSIAQILSDGRVASRRAALDVHEWEGRFRGQPARFKMTSVIGHVY 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF + W DP L+ A +K E+NPKAH+C HL +E RGC LVLWLDCDREGE
Sbjct: 61 SIDFTAAFNSWDKVDPSQLYDAPTVKQEANPKAHVCEHLQREGRGCDVLVLWLDCDREGE 120
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 121 NICFEVMDN 129
Score = 51.2 bits (121), Expect(2) = 7e-50
Identities = 23/38 (60%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++T ++ A++NLV PN EALAVDARQE+D
Sbjct: 151 FRARFSAITAPEIRAAMNNLVSPNEAEALAVDARQELD 188
[13][TOP]
>UniRef100_Q680E4 DNA topoisomerase n=1 Tax=Arabidopsis thaliana RepID=Q680E4_ARATH
Length = 838
Score = 130 bits (326), Expect(3) = 1e-48
Identities = 57/82 (69%), Positives = 68/82 (82%), Gaps = 3/82 (3%)
Frame = +3
Query: 237 HVFSV---DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
H+ SV DFP KYQ+W+ DP DLF A ++K ESNPKAHICRHL+ EARGC ++VLWLD
Sbjct: 30 HLLSVMFSDFPEKYQNWATIDPQDLFDAPIIKKESNPKAHICRHLSNEARGCSYMVLWLD 89
Query: 408 CDREGENICFEVIQSTGFNVND 473
CDREGENICFEVI+STGF++ D
Sbjct: 90 CDREGENICFEVIESTGFDMKD 111
Score = 70.9 bits (172), Expect(3) = 1e-48
Identities = 34/38 (89%), Positives = 36/38 (94%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFSSVTEKD+ KA+DNLV PNRDEALAVDARQEID
Sbjct: 117 YRARFSSVTEKDISKAMDNLVEPNRDEALAVDARQEID 154
Score = 37.7 bits (86), Expect(3) = 1e-48
Identities = 18/36 (50%), Positives = 23/36 (63%)
Frame = +1
Query: 139 ARCLQGKEAQKFMNLRGSFLVPLHILK*HRLLVMYS 246
ARCLQG+ Q+ MNL F HI++ H L VM+S
Sbjct: 2 ARCLQGEAVQRCMNLMACFEASKHIIELHLLSVMFS 37
[14][TOP]
>UniRef100_A5BC76 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BC76_VITVI
Length = 1226
Score = 188 bits (478), Expect = 2e-46
Identities = 94/137 (68%), Positives = 104/137 (75%), Gaps = 4/137 (2%)
Frame = +3
Query: 66 MAP----KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVI 233
MAP K+LMVAEKPS ALSIAS LS G M TR+ S EVHEF G F GS A +K TSVI
Sbjct: 122 MAPPKPHKILMVAEKPSSALSIASTLSDGHMSTRRSSIEVHEFNGTFRGSNAQYKATSVI 181
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
FSVDFP KYQDW+ DPLD FQA + K E NPKAHICR L+QEAR C LVLWLDCD
Sbjct: 182 DMFFSVDFPAKYQDWTIVDPLDFFQAPIHKAEXNPKAHICRRLSQEARVCGHLVLWLDCD 241
Query: 414 REGENICFEVIQSTGFN 464
REG+NICFEV++ TGF+
Sbjct: 242 REGDNICFEVVECTGFH 258
[15][TOP]
>UniRef100_A3FPU5 DNA topoisomerase n=2 Tax=Cryptosporidium parvum RepID=A3FPU5_CRYPV
Length = 835
Score = 164 bits (415), Expect(2) = 9e-46
Identities = 78/136 (57%), Positives = 102/136 (75%), Gaps = 1/136 (0%)
Frame = +3
Query: 66 MAP-KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHV 242
M+P KVLMVAEKPSI+ +I+ +LS+G++ TR+G T VHEF G F+G F+VTSV GHV
Sbjct: 1 MSPIKVLMVAEKPSISDTISRILSNGKLDTRRGKTPVHEFNGTFMGMNVQFRVTSVAGHV 60
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
F +DFP Y +W TDP+ LF A ++KNES+ K + HL +E++GC +LVLWLDCDREG
Sbjct: 61 FEIDFPQSYSNWEKTDPVSLFDAPIIKNESSSK--MVSHLEKESKGCSYLVLWLDCDREG 118
Query: 423 ENICFEVIQSTGFNVN 470
ENICFEVI N++
Sbjct: 119 ENICFEVINVVSNNMS 134
Score = 43.9 bits (102), Expect(2) = 9e-46
Identities = 19/38 (50%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FSS++ D+ A+ NL PN++E+ AVD RQE+D
Sbjct: 144 FRAKFSSISPGDIFFAMKNLTFPNKNESDAVDVRQELD 181
[16][TOP]
>UniRef100_B6ADG7 DNA topoisomerase n=1 Tax=Cryptosporidium muris RN66
RepID=B6ADG7_9CRYT
Length = 857
Score = 152 bits (383), Expect(2) = 1e-45
Identities = 76/125 (60%), Positives = 90/125 (72%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
P VLMVAEKPSIA ++A VLS+G + TR+ T VHE+ F A FKVTSV GHVF
Sbjct: 29 PTVLMVAEKPSIAETVAKVLSNGNLNTRQCKTPVHEYTAYFQHKRALFKVTSVSGHVFET 88
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP KY +W + DP+DLF +KNES+ K + HL +EA+ C FLVLWLDCDREGENI
Sbjct: 89 DFPSKYSNWESIDPVDLFDLPTVKNESSSK--MIAHLLREAKNCDFLVLWLDCDREGENI 146
Query: 432 CFEVI 446
CFEVI
Sbjct: 147 CFEVI 151
Score = 55.8 bits (133), Expect(2) = 1e-45
Identities = 26/41 (63%), Positives = 33/41 (80%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFSSV KDV++A++NL PNRDEA AVD RQE+D
Sbjct: 166 LWIFRARFSSVAPKDVIEAMNNLKSPNRDEADAVDVRQELD 206
[17][TOP]
>UniRef100_UPI0000D55E1A PREDICTED: similar to prokaryotic DNA topoisomerase n=1
Tax=Tribolium castaneum RepID=UPI0000D55E1A
Length = 852
Score = 153 bits (387), Expect(2) = 6e-45
Identities = 78/144 (54%), Positives = 98/144 (68%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
V MVAEKPS+A S+AS+LS+G TRKGS VHE+ G F G+PA K+TSV GHV
Sbjct: 4 VFMVAEKPSLAASLASILSNGSNSTRKGSNGICSVHEWNGTFQGAPARLKMTSVCGHVMG 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
VDF KY +W DP++LF + K E+ PK + L+ EA+GC +LVLWLDCD+EGEN
Sbjct: 64 VDFISKYNNWDRVDPVELFSCPIEKKEATPKFKMPAFLSHEAKGCDYLVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVN-DVLSCTVFF 497
ICFEV+ S ++N DV S V F
Sbjct: 124 ICFEVMNSVARSMNGDVYSDKVTF 147
Score = 52.0 bits (123), Expect(2) = 6e-45
Identities = 22/38 (57%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++T+KD+ A +NL PN +EA +VDARQE+D
Sbjct: 147 FRARFSAITDKDIKAAFNNLAHPNENEARSVDARQELD 184
[18][TOP]
>UniRef100_UPI000060F1C3 topoisomerase (DNA) III beta n=1 Tax=Gallus gallus
RepID=UPI000060F1C3
Length = 863
Score = 148 bits (374), Expect(2) = 1e-44
Identities = 73/129 (56%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M +RKG VHE+ G F+G AHFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSRKGLNGVCSVHEYTGSFIGQSAHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF +A K E+NPK + + L E RGC +VLWLDCD+EGE
Sbjct: 64 LDFIGKYNSWDKVDPAELFSKAPTEKKEANPKLTMVKFLQVEGRGCDSIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 55.8 bits (133), Expect(2) = 1e-44
Identities = 27/53 (50%), Positives = 39/53 (73%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N+ S M YRA+FSS+T+ D+ A+++L PN +EAL+VDARQE+D
Sbjct: 133 VLPVMNKSPSTERMIYRAKFSSITDTDICNAMNHLGEPNLNEALSVDARQELD 185
[19][TOP]
>UniRef100_Q5ZK71 DNA topoisomerase n=1 Tax=Gallus gallus RepID=Q5ZK71_CHICK
Length = 862
Score = 148 bits (374), Expect(2) = 1e-44
Identities = 73/129 (56%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M +RKG VHE+ G F+G AHFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSRKGLNGVCSVHEYTGSFIGQSAHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF +A K E+NPK + + L E RGC +VLWLDCD+EGE
Sbjct: 64 LDFIGKYNSWDKVDPAELFSKAPTEKKEANPKLTMVKFLQVEGRGCDSIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 55.8 bits (133), Expect(2) = 1e-44
Identities = 27/53 (50%), Positives = 39/53 (73%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N+ S M YRA+FSS+T+ D+ A+++L PN +EAL+VDARQE+D
Sbjct: 133 VLPVMNKSPSTERMIYRAKFSSITDTDICNAMNHLGEPNLNEALSVDARQELD 185
[20][TOP]
>UniRef100_B3RKZ5 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3RKZ5_TRIAD
Length = 841
Score = 148 bits (374), Expect(2) = 2e-44
Identities = 72/126 (57%), Positives = 91/126 (72%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLM+AEKPS+A SIA +LS G M TRKG +V+E+ G F G A F VTSV GHV+S
Sbjct: 4 VLMIAEKPSLAQSIAKILSRGTMKTRKGIAKPCQVYEYSGTFHGQQARFSVTSVCGHVYS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF +Y +W A DP+DL+ A+V K ++NP +I + L E +G +LVLWLDCDREGEN
Sbjct: 64 LDFLPQYNNWDAVDPVDLYDAEVKKKDANPDQNIVKFLKHEGQGIDYLVLWLDCDREGEN 123
Query: 429 ICFEVI 446
ICFEVI
Sbjct: 124 ICFEVI 129
Score = 55.5 bits (132), Expect(2) = 2e-44
Identities = 21/38 (55%), Positives = 35/38 (92%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T+KD+ +A++ L+ PN++EAL+VDARQE+D
Sbjct: 145 FRAKFSAITDKDIFRAMETLITPNKNEALSVDARQELD 182
[21][TOP]
>UniRef100_UPI000065FF0F UPI000065FF0F related cluster n=1 Tax=Takifugu rubripes
RepID=UPI000065FF0F
Length = 665
Score = 149 bits (376), Expect(2) = 2e-44
Identities = 73/129 (56%), Positives = 94/129 (72%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G +RKG + V+E+ G FLG AHFK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSKGNCSSRKGLNGACSVYEYTGSFLGQAAHFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK ++ + L EA+GC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMIKFLQVEAKGCCYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 54.7 bits (130), Expect(2) = 2e-44
Identities = 24/38 (63%), Positives = 34/38 (89%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ KA+++L PN++EALAVDARQE+D
Sbjct: 148 YRAKFSSITDTDICKAMNSLGDPNQNEALAVDARQELD 185
[22][TOP]
>UniRef100_C1DYX0 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1DYX0_9CHLO
Length = 861
Score = 157 bits (398), Expect(2) = 2e-44
Identities = 77/127 (60%), Positives = 91/127 (71%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
P VL VAEKPS+A SIA LS G+ +R+G EVHEFE F G+ HFKVT+VIGHV S+
Sbjct: 5 PVVLCVAEKPSLAASIAGFLSEGKHRSRRGGQEVHEFERDFNGARCHFKVTAVIGHVLSI 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP K+Q W DP LF A V K E+ PKA + HL +EA+G L+LWLDCDREGENI
Sbjct: 65 DFPAKFQSWD-LDPAILFDAPVQKKEATPKARVVEHLEREAKGASHLILWLDCDREGENI 123
Query: 432 CFEVIQS 452
CFEVI +
Sbjct: 124 CFEVIDA 130
Score = 45.8 bits (107), Expect(2) = 2e-44
Identities = 21/38 (55%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS+V+++ + +A+ L PNR EALAVDARQE+D
Sbjct: 145 HRAKFSAVSKESIERAMRTLGAPNRAEALAVDARQELD 182
[23][TOP]
>UniRef100_C5KCJ6 DNA topoisomerase n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5KCJ6_9ALVE
Length = 850
Score = 154 bits (390), Expect(2) = 8e-44
Identities = 72/139 (51%), Positives = 101/139 (72%), Gaps = 3/139 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIG 236
M +VLMVAEKPSIA ++A L G+ +R+G + +VHEF G+F GSPA K+TSV G
Sbjct: 1 MVQQVLMVAEKPSIAEALAKSLCKGKYNSRRGVSPVGQVHEFNGEFQGSPAWLKITSVAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
HV+S+DFP + +W DP LF+++ ++ E+NPK + +HL E++GC LVLWLDCDR
Sbjct: 61 HVYSIDFPPELNNWDRVDPAKLFESKTVQKEANPKQRMPQHLRSESKGCDHLVLWLDCDR 120
Query: 417 EGENICFEVIQSTGFNVND 473
EGENIC+EV+Q+ N++D
Sbjct: 121 EGENICYEVMQNVAPNLSD 139
Score = 47.0 bits (110), Expect(2) = 8e-44
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FSS+ KD+ A NL PN++EAL+VDARQEID
Sbjct: 144 WRAKFSSLVAKDLQHAYRNLGYPNQNEALSVDARQEID 181
[24][TOP]
>UniRef100_B7Q7K8 Topoisomerase I, putative n=1 Tax=Ixodes scapularis
RepID=B7Q7K8_IXOSC
Length = 857
Score = 151 bits (381), Expect(2) = 1e-43
Identities = 72/126 (57%), Positives = 91/126 (72%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKP++A S+A++LS+G M +RKG + V+E+ GKF PA FK+TSV GHV +
Sbjct: 4 VLMVAEKPALAQSLAAILSNGTMKSRKGISSACTVYEYMGKFKNEPARFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
DF GKY W DP +LF A K E+NPK + R L +E +GC +LVLWLDCD+EGEN
Sbjct: 64 TDFTGKYNSWDRVDPAELFSAPTEKKEANPKLQLPRFLEKEGQGCDYLVLWLDCDKEGEN 123
Query: 429 ICFEVI 446
ICFEVI
Sbjct: 124 ICFEVI 129
Score = 50.1 bits (118), Expect(2) = 1e-43
Identities = 21/38 (55%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T+KD+ A++ LV PN +EA +VDARQE+D
Sbjct: 148 FRAKFSAITDKDIKAAMNMLVEPNENEARSVDARQELD 185
[25][TOP]
>UniRef100_UPI00017F0948 PREDICTED: topoisomerase (DNA) III beta n=1 Tax=Sus scrofa
RepID=UPI00017F0948
Length = 859
Score = 150 bits (378), Expect(2) = 2e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P HFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIARILSRGNMSSHKGLNGTCSVHEYTGTFAGQPVHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 50.4 bits (119), Expect(2) = 2e-43
Identities = 25/53 (47%), Positives = 36/53 (67%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + NQ +RARFSS+T+ D+ A+ +L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNQAHGSEKTVFRARFSSITDTDICNAMAHLGEPDHNEALSVDARQELD 185
[26][TOP]
>UniRef100_C5LF56 DNA topoisomerase n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5LF56_9ALVE
Length = 813
Score = 153 bits (387), Expect(2) = 2e-43
Identities = 72/139 (51%), Positives = 101/139 (72%), Gaps = 3/139 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIG 236
M +VLMVAEKPSIA ++A L G+ +R+G + +VHEF G+F GSPA K+TSV G
Sbjct: 1 MVQQVLMVAEKPSIAEALAKSLCKGKYNSRRGVSPVGQVHEFNGEFQGSPAWLKITSVAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
HV+S+DFP + +W DP LF+++ ++ E+NPK + +HL E++GC LVLWLDCDR
Sbjct: 61 HVYSIDFPPELNNWDRVDPAKLFESKTVQKEANPKQRMPQHLRSESKGCDHLVLWLDCDR 120
Query: 417 EGENICFEVIQSTGFNVND 473
EGENIC+EV+Q+ N++D
Sbjct: 121 EGENICYEVMQNVVPNLSD 139
Score = 47.0 bits (110), Expect(2) = 2e-43
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FSS+ KD+ A NL PN++EAL+VDARQEID
Sbjct: 144 WRAKFSSLVAKDLQHAYRNLGYPNQNEALSVDARQEID 181
[27][TOP]
>UniRef100_UPI000069DC09 DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III
beta- 1). n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069DC09
Length = 858
Score = 145 bits (367), Expect(2) = 2e-43
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G +RKG + VHE+ G F+G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNASSRKGLNGACSVHEYTGSFMGQTVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK + + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLSMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 54.3 bits (129), Expect(2) = 2e-43
Identities = 23/38 (60%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+L A++ L PN++EAL+VDARQE+D
Sbjct: 148 YRAKFSSITDTDILNAMNRLGEPNKNEALSVDARQELD 185
[28][TOP]
>UniRef100_UPI0000613AEF Topoisomerase (DNA) III beta n=1 Tax=Bos taurus RepID=UPI0000613AEF
Length = 856
Score = 149 bits (376), Expect(2) = 2e-43
Identities = 74/129 (57%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M +RKG + VHE+ G F G PA FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIARILSRGSMSSRKGLNGTCSVHEYSGAFEGQPARFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC +VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDCIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 50.8 bits (120), Expect(2) = 2e-43
Identities = 26/53 (49%), Positives = 36/53 (67%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + NQ S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNQARSGEQTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[29][TOP]
>UniRef100_UPI0000EBDA0D PREDICTED: topoisomerase (DNA) III beta n=1 Tax=Bos taurus
RepID=UPI0000EBDA0D
Length = 855
Score = 149 bits (376), Expect(2) = 2e-43
Identities = 74/129 (57%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M +RKG + VHE+ G F G PA FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIARILSRGSMSSRKGLNGTCSVHEYSGAFEGQPARFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC +VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDCIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 50.8 bits (120), Expect(2) = 2e-43
Identities = 26/53 (49%), Positives = 36/53 (67%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + NQ S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNQARSGEQTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[30][TOP]
>UniRef100_B0WQT7 DNA topoisomerase n=1 Tax=Culex quinquefasciatus RepID=B0WQT7_CULQU
Length = 855
Score = 144 bits (363), Expect(2) = 2e-43
Identities = 71/142 (50%), Positives = 91/142 (64%), Gaps = 3/142 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKPS+A S+A +LS+G+ +RKGS VHE+ G F G FK+TSV GH+ +
Sbjct: 5 LMVAEKPSLAQSLAQILSNGKCSSRKGSNNACSVHEWVGNFHGQQTRFKMTSVCGHIMGL 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
+F GKY W DP DLF K ES P + L+ EA+GC +LVLWLDCD+EGENI
Sbjct: 65 EFVGKYNSWDKVDPADLFTCATEKKESTPNLRMPAFLSHEAKGCDYLVLWLDCDKEGENI 124
Query: 432 CFEVIQSTGFNVNDVLSCTVFF 497
CFEV+ S + +V S V +
Sbjct: 125 CFEVMASVANTIPNVYSNRVTY 146
Score = 55.8 bits (133), Expect(2) = 2e-43
Identities = 23/38 (60%), Positives = 34/38 (89%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FS++TEKD+ A++NL++PN +EA +VDARQE+D
Sbjct: 146 YRAKFSAITEKDIKYAMENLIQPNENEAKSVDARQELD 183
[31][TOP]
>UniRef100_Q0V7N8 Topoisomerase (DNA) III beta (Fragment) n=1 Tax=Bos taurus
RepID=Q0V7N8_BOVIN
Length = 295
Score = 149 bits (376), Expect(2) = 2e-43
Identities = 74/129 (57%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M +RKG + VHE+ G F G PA FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIARILSRGSMSSRKGLNGTCSVHEYSGAFEGQPARFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC +VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDCIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 50.8 bits (120), Expect(2) = 2e-43
Identities = 26/53 (49%), Positives = 36/53 (67%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + NQ S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNQARSGEQTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[32][TOP]
>UniRef100_UPI000024FFBD topoisomerase (DNA) III beta n=1 Tax=Rattus norvegicus
RepID=UPI000024FFBD
Length = 862
Score = 149 bits (377), Expect(2) = 4e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VH++ G F G P HFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQPVHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 49.7 bits (117), Expect(2) = 4e-43
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMTRLTEPDHNEALSVDARQELD 185
[33][TOP]
>UniRef100_A7RW77 DNA topoisomerase n=1 Tax=Nematostella vectensis RepID=A7RW77_NEMVE
Length = 856
Score = 147 bits (372), Expect(2) = 5e-43
Identities = 73/134 (54%), Positives = 94/134 (70%), Gaps = 3/134 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA LS+G+M +RKG + VHE+ G F P FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKFLSNGRMNSRKGLNGACSVHEYSGSFRNEPVKFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF KY +W A DPL+LF A LK E+ K + + L+ EA+G +LVLWLDCD+EGEN
Sbjct: 64 LDFHHKYNNWDAVDPLELFTATTLKKEATEKLQMPKFLSHEAKGVDYLVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVN 470
ICFEV++ ++N
Sbjct: 124 ICFEVMECVRNSMN 137
Score = 51.2 bits (121), Expect(2) = 5e-43
Identities = 21/38 (55%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++TEKD+ A+ L +PN++E+L+VDARQE+D
Sbjct: 146 FRAKFSAITEKDIAGAMQKLGQPNKNESLSVDARQELD 183
[34][TOP]
>UniRef100_Q9Z321 DNA topoisomerase 3-beta-1 n=2 Tax=Mus musculus RepID=TOP3B_MOUSE
Length = 862
Score = 149 bits (377), Expect(2) = 7e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VH++ G F G P HFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQPVHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.9 bits (115), Expect(2) = 7e-43
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMTRLSEPDHNEALSVDARQELD 185
[35][TOP]
>UniRef100_UPI000056AA95 Novel protein similar to vertebrate topoisomerase (DNA) III beta
(TOP3B) n=1 Tax=Danio rerio RepID=UPI000056AA95
Length = 861
Score = 146 bits (368), Expect(2) = 7e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G TRKG + VHE+ G F G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSKGSCSTRKGLNGACSVHEYMGSFTGQNVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK ++ + L EA+GC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEAKGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 52.4 bits (124), Expect(2) = 7e-43
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PN++EAL+VDARQE+D
Sbjct: 148 YRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELD 185
[36][TOP]
>UniRef100_Q9JJ62 DNA topoisomerase n=1 Tax=Mus musculus RepID=Q9JJ62_MOUSE
Length = 464
Score = 149 bits (377), Expect(2) = 7e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VH++ G F G P HFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQPVHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.9 bits (115), Expect(2) = 7e-43
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMTRLSEPDHNEALSVDARQELD 185
[37][TOP]
>UniRef100_UPI0000F4B922 UPI0000F4B922 related cluster n=1 Tax=Mus musculus
RepID=UPI0000F4B922
Length = 229
Score = 149 bits (377), Expect(2) = 7e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VH++ G F G P HFK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQPVHFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.9 bits (115), Expect(2) = 7e-43
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMTRLSEPDHNEALSVDARQELD 185
[38][TOP]
>UniRef100_A5WV27 Novel protein similar to vertebrate topoisomerase (DNA) III beta
(TOP3B) (Fragment) n=1 Tax=Danio rerio
RepID=A5WV27_DANRE
Length = 193
Score = 146 bits (368), Expect(2) = 7e-43
Identities = 72/129 (55%), Positives = 91/129 (70%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G TRKG + VHE+ G F G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSKGSCSTRKGLNGACSVHEYMGSFTGQNVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK ++ + L EA+GC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEAKGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 52.4 bits (124), Expect(2) = 7e-43
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PN++EAL+VDARQE+D
Sbjct: 148 YRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELD 185
[39][TOP]
>UniRef100_Q7ZWP8 DNA topoisomerase n=1 Tax=Xenopus laevis RepID=Q7ZWP8_XENLA
Length = 858
Score = 144 bits (362), Expect(2) = 9e-43
Identities = 70/129 (54%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G +RKG + VHE+ G F+G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNASSRKGLNGACSVHEYTGSFMGQNVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK ++ + L E R C ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEGRSCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 54.3 bits (129), Expect(2) = 9e-43
Identities = 23/38 (60%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+L A++ L PN++EAL+VDARQE+D
Sbjct: 148 YRAKFSSITDTDILNAMNRLGEPNKNEALSVDARQELD 185
[40][TOP]
>UniRef100_Q16PL8 DNA topoisomerase n=1 Tax=Aedes aegypti RepID=Q16PL8_AEDAE
Length = 856
Score = 142 bits (358), Expect(2) = 9e-43
Identities = 68/142 (47%), Positives = 93/142 (65%), Gaps = 3/142 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKPS+A S+A++LS+G+ +RKGS VHE+ G F G FK+TSV GH+ +
Sbjct: 5 LMVAEKPSLAASLATILSNGKCSSRKGSNNACSVHEWFGNFRGEQVKFKMTSVCGHIMGL 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
+F GK+ W DP +LF K ES P + L+QEA+GC +L+LWLDCD+EGENI
Sbjct: 65 EFVGKFNSWDKVDPAELFSCPTEKKESTPNLRMPAFLSQEAKGCEYLILWLDCDKEGENI 124
Query: 432 CFEVIQSTGFNVNDVLSCTVFF 497
CFEV+ + + +V S V +
Sbjct: 125 CFEVMAAVSGVMRNVFSNRVTY 146
Score = 55.8 bits (133), Expect(2) = 9e-43
Identities = 23/38 (60%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FS++T+KD+ A+DNL+ PN +EA +VDARQE+D
Sbjct: 146 YRAKFSAITDKDIKYAMDNLIHPNENEAKSVDARQELD 183
[41][TOP]
>UniRef100_UPI00005A4AF9 PREDICTED: similar to topoisomerase (DNA) III beta isoform 4 n=1
Tax=Canis lupus familiaris RepID=UPI00005A4AF9
Length = 874
Score = 147 bits (372), Expect(2) = 4e-42
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGTCSVHEYSGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.1 bits (113), Expect(2) = 4e-42
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNPTHSGEKTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[42][TOP]
>UniRef100_UPI00005A4AF8 PREDICTED: similar to topoisomerase (DNA) III beta isoform 1 n=1
Tax=Canis lupus familiaris RepID=UPI00005A4AF8
Length = 862
Score = 147 bits (372), Expect(2) = 4e-42
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGTCSVHEYSGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.1 bits (113), Expect(2) = 4e-42
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNPTHSGEKTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[43][TOP]
>UniRef100_UPI00005A4AFB PREDICTED: similar to topoisomerase (DNA) III beta isoform 6 n=1
Tax=Canis lupus familiaris RepID=UPI00005A4AFB
Length = 848
Score = 147 bits (372), Expect(2) = 4e-42
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGTCSVHEYSGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.1 bits (113), Expect(2) = 4e-42
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNPTHSGEKTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[44][TOP]
>UniRef100_UPI00005A4AFA PREDICTED: similar to topoisomerase (DNA) III beta isoform 5 n=1
Tax=Canis lupus familiaris RepID=UPI00005A4AFA
Length = 844
Score = 147 bits (372), Expect(2) = 4e-42
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGTCSVHEYSGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.1 bits (113), Expect(2) = 4e-42
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNPTHSGEKTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 185
[45][TOP]
>UniRef100_UPI000192409E PREDICTED: similar to topoisomerase (DNA) III beta, partial n=1
Tax=Hydra magnipapillata RepID=UPI000192409E
Length = 412
Score = 141 bits (356), Expect(2) = 5e-42
Identities = 69/126 (54%), Positives = 88/126 (69%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+ALSI+ +LS G + T+KG + +HEF G FLG FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLALSISKILSGGNINTKKGVSSACPIHEFNGSFLGENVKFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF G + +W A +P++LF A K E+ K +I +HL + FLVLWLDCD+EGEN
Sbjct: 64 LDFKGYFNNWDAVEPIELFSAATQKIEAQEKLNIVKHLKIAGKDVDFLVLWLDCDKEGEN 123
Query: 429 ICFEVI 446
ICFEVI
Sbjct: 124 ICFEVI 129
Score = 54.3 bits (129), Expect(2) = 5e-42
Identities = 23/40 (57%), Positives = 33/40 (82%)
Frame = +1
Query: 472 MFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
M YRA FS++T+KD+ A+ NL PN++E+L+VDARQE+D
Sbjct: 143 MIYRAHFSAITDKDIKNAMHNLKDPNKNESLSVDARQELD 182
[46][TOP]
>UniRef100_C0H9Z6 DNA topoisomerase n=1 Tax=Salmo salar RepID=C0H9Z6_SALSA
Length = 857
Score = 142 bits (359), Expect(2) = 6e-42
Identities = 70/129 (54%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G +RKG + VHE+ G F G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSKGSCSSRKGLNGACSVHEYMGTFSGQSVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK ++ + L E +GC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFTKAPTEKKEANPKLNMVKFLQVEGKGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 52.8 bits (125), Expect(2) = 6e-42
Identities = 23/38 (60%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PNR+EAL+VDARQE+D
Sbjct: 148 YRAKFSSITDTDIWAAMNKLGEPNRNEALSVDARQELD 185
[47][TOP]
>UniRef100_UPI00006D2D36 PREDICTED: similar to topoisomerase (DNA) III beta isoform 5 n=1
Tax=Macaca mulatta RepID=UPI00006D2D36
Length = 862
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.4 bits (111), Expect(2) = 1e-41
Identities = 24/53 (45%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N+ +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNKAYGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[48][TOP]
>UniRef100_UPI000155EC4A PREDICTED: topoisomerase (DNA) III beta n=1 Tax=Equus caballus
RepID=UPI000155EC4A
Length = 862
Score = 145 bits (366), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 89/129 (68%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSMSSHKGLNGTCSVHEYTGTFAGQAVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 49.3 bits (116), Expect(2) = 1e-41
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + NQ +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNQAHGGEKTVFRARFSSITDTDICNAMARLGEPDHNEALSVDARQELD 185
[49][TOP]
>UniRef100_UPI0000D9C866 PREDICTED: similar to topoisomerase (DNA) III beta isoform 1 n=1
Tax=Macaca mulatta RepID=UPI0000D9C866
Length = 730
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.4 bits (111), Expect(2) = 1e-41
Identities = 24/53 (45%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N+ +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 133 VLPVMNKAYGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[50][TOP]
>UniRef100_UPI0000E259FA PREDICTED: topoisomerase (DNA) III beta n=1 Tax=Pan troglodytes
RepID=UPI0000E259FA
Length = 956
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 98 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 157
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 158 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 217
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 218 NICFEVLDA 226
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 242 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 279
[51][TOP]
>UniRef100_A8K4N2 DNA topoisomerase n=1 Tax=Homo sapiens RepID=A8K4N2_HUMAN
Length = 862
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[52][TOP]
>UniRef100_O95985 DNA topoisomerase 3-beta-1 n=1 Tax=Homo sapiens RepID=TOP3B_HUMAN
Length = 862
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[53][TOP]
>UniRef100_O95985-2 Isoform 2 of DNA topoisomerase 3-beta-1 n=1 Tax=Homo sapiens
RepID=O95985-2
Length = 730
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[54][TOP]
>UniRef100_O95985-3 Isoform 3 of DNA topoisomerase 3-beta-1 n=1 Tax=Homo sapiens
RepID=O95985-3
Length = 707
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[55][TOP]
>UniRef100_C9JEI7 Putative uncharacterized protein TOP3B n=1 Tax=Homo sapiens
RepID=C9JEI7_HUMAN
Length = 246
Score = 147 bits (371), Expect(2) = 1e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.0 bits (110), Expect(2) = 1e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 185
[56][TOP]
>UniRef100_A9V3W6 DNA topoisomerase n=1 Tax=Monosiga brevicollis RepID=A9V3W6_MONBE
Length = 803
Score = 141 bits (355), Expect(2) = 2e-41
Identities = 69/128 (53%), Positives = 88/128 (68%), Gaps = 3/128 (2%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHV 242
P VLMVAEKPS+A S+A +LS+ +R S VHE+ G F+G A FK TSV+GHV
Sbjct: 4 PTVLMVAEKPSLAKSLAWILSNHSATSRPSRSKSCTVHEYSGDFMGQQAQFKFTSVMGHV 63
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
S+DF +Y +W T P +LF A+ K ++NPKAH+ L E +G +LVLWLDCDREG
Sbjct: 64 MSLDFLPQYNNWERTPPRELFDAETEKKDANPKAHVREALRSEGKGVDYLVLWLDCDREG 123
Query: 423 ENICFEVI 446
ENICFEV+
Sbjct: 124 ENICFEVM 131
Score = 52.8 bits (125), Expect(2) = 2e-41
Identities = 23/38 (60%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++TEKD+ A+ LV PN +E+LAVDARQE+D
Sbjct: 148 FRAKFSAITEKDIKAAMRTLVAPNENESLAVDARQELD 185
[57][TOP]
>UniRef100_C1N1P2 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1N1P2_9CHLO
Length = 862
Score = 149 bits (375), Expect(2) = 2e-41
Identities = 74/127 (58%), Positives = 88/127 (69%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
P VL VAEKPS+A SIA LS G TR+G +VHEF + G FKVT+V GHV S+
Sbjct: 2 PTVLCVAEKPSLAASIAGFLSDGTHKTRRGGQDVHEFVRVYDGQRCDFKVTAVCGHVLSI 61
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP KYQDW DP LF A V+K E++P A + HL QEA+G LVLWLDCDREGENI
Sbjct: 62 DFPDKYQDWD-VDPGALFDAPVVKKEASPGARVVSHLEQEAKGATHLVLWLDCDREGENI 120
Query: 432 CFEVIQS 452
C+EV+ +
Sbjct: 121 CYEVVDA 127
Score = 44.7 bits (104), Expect(2) = 2e-41
Identities = 20/37 (54%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+V+++ + +A+ L PNR EA+AVDARQE+D
Sbjct: 146 RAKFSAVSKESIERAMATLGTPNRHEAMAVDARQELD 182
[58][TOP]
>UniRef100_UPI0000D8FD31 PREDICTED: similar to Topoisomerase (DNA) III beta n=1
Tax=Monodelphis domestica RepID=UPI0000D8FD31
Length = 862
Score = 144 bits (363), Expect(2) = 3e-41
Identities = 70/129 (54%), Positives = 88/129 (68%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHEYSGSFSGQTVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF +A K E+NPK + + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFTGKYNHWDRVDPAELFSKAPTEKKEANPKLSMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 48.9 bits (115), Expect(2) = 3e-41
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 148 FRARFSSITDTDICNAMSRLGEPDHNEALSVDARQELD 185
[59][TOP]
>UniRef100_B1H2R2 DNA topoisomerase n=1 Tax=Xenopus (Silurana) tropicalis
RepID=B1H2R2_XENTR
Length = 482
Score = 145 bits (367), Expect(2) = 3e-41
Identities = 71/129 (55%), Positives = 90/129 (69%), Gaps = 4/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G +RKG + VHE+ G F+G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSASSRKGLNGACSVHEYTGSFMGQTVRFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY +W DP +LF +A K E+NPK + + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLSMVKFLQVEGRGCDYVVLWLDCDKEGE 123
Query: 426 NICFEVIQS 452
NICFEV+ +
Sbjct: 124 NICFEVLDA 132
Score = 47.4 bits (111), Expect(2) = 3e-41
Identities = 20/34 (58%), Positives = 29/34 (85%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDAR 579
YRA+FSS+T+ D+L A++ L PN++EAL+VDAR
Sbjct: 148 YRAKFSSITDTDILNAMNRLGEPNKNEALSVDAR 181
[60][TOP]
>UniRef100_O96651 DNA topoisomerase 3-beta n=1 Tax=Drosophila melanogaster
RepID=TOP3B_DROME
Length = 875
Score = 139 bits (351), Expect(2) = 5e-41
Identities = 70/144 (48%), Positives = 95/144 (65%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPA-HFKVTSVIGHVF 245
VLMVAEKPS+A S+A +LS+G+ ++G+ HE+ G F + HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP+ LF K E+NPK ++ + L EARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +N+V S V +
Sbjct: 124 NICFEVMDAVKHVINNVYSDQVTY 147
Score = 52.8 bits (125), Expect(2) = 5e-41
Identities = 23/38 (60%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ KA++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELD 184
[61][TOP]
>UniRef100_B9QEY2 DNA topoisomerase n=1 Tax=Toxoplasma gondii VEG RepID=B9QEY2_TOXGO
Length = 842
Score = 151 bits (382), Expect(2) = 5e-41
Identities = 74/129 (57%), Positives = 89/129 (68%), Gaps = 3/129 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPAHFKVTSVIG 236
MAP VLMVAEKPSIA +IA +LS G RKG T V EF G F G FKVTS G
Sbjct: 1 MAPAVLMVAEKPSIAETIARILSGGNFHKRKGISPVTSVWEFSGSFRGEAVLFKVTSTAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H++ DFP ++ DW T+P++LF A V+K E+N K + HL +EA GC+ LVLWLDCDR
Sbjct: 61 HIYQTDFPRQFNDWEKTNPIELFDAPVVKVEANAKHRLPAHLQKEAHGCKHLVLWLDCDR 120
Query: 417 EGENICFEV 443
EGENICFE+
Sbjct: 121 EGENICFEI 129
Score = 40.8 bits (94), Expect(2) = 5e-41
Identities = 18/38 (47%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++ D+ +A+ L PN++EA +VDARQE+D
Sbjct: 130 WRAKFSALAPADIQQAMRTLGTPNKNEADSVDARQELD 167
[62][TOP]
>UniRef100_B6KLI4 DNA topoisomerase n=1 Tax=Toxoplasma gondii ME49 RepID=B6KLI4_TOXGO
Length = 841
Score = 151 bits (382), Expect(2) = 5e-41
Identities = 74/129 (57%), Positives = 89/129 (68%), Gaps = 3/129 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPAHFKVTSVIG 236
MAP VLMVAEKPSIA +IA +LS G RKG T V EF G F G FKVTS G
Sbjct: 1 MAPAVLMVAEKPSIAETIARILSGGNFHKRKGISPVTSVWEFSGSFRGEAVLFKVTSTAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H++ DFP ++ DW T+P++LF A V+K E+N K + HL +EA GC+ LVLWLDCDR
Sbjct: 61 HIYQTDFPRQFNDWEKTNPIELFDAPVVKVEANAKHRLPAHLQKEAHGCKHLVLWLDCDR 120
Query: 417 EGENICFEV 443
EGENICFE+
Sbjct: 121 EGENICFEI 129
Score = 40.8 bits (94), Expect(2) = 5e-41
Identities = 18/38 (47%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++ D+ +A+ L PN++EA +VDARQE+D
Sbjct: 130 WRAKFSALAPADIQQAMRTLGTPNKNEADSVDARQELD 167
[63][TOP]
>UniRef100_UPI00018609AC hypothetical protein BRAFLDRAFT_119055 n=1 Tax=Branchiostoma
floridae RepID=UPI00018609AC
Length = 858
Score = 145 bits (365), Expect(2) = 6e-41
Identities = 73/134 (54%), Positives = 90/134 (67%), Gaps = 3/134 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + +RKG + VHE+ GKF G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAQILSGGSLKSRKGINGACSVHEYTGKFHGESVKFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF G Y +W DP DLF+A K E+NP + + L E RG LVLWLDCD+EGEN
Sbjct: 64 LDFQGVYNNWDRVDPADLFRAPTNKKEANPNLKMPKFLELEGRGADILVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVN 470
ICFEVI + ++N
Sbjct: 124 ICFEVIDAVRPSMN 137
Score = 47.0 bits (110), Expect(2) = 6e-41
Identities = 20/38 (52%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YR++FS++TE D+ A+ L PN +EA++VDARQE+D
Sbjct: 147 YRSKFSAITETDIRGAMMRLGEPNENEAMSVDARQELD 184
[64][TOP]
>UniRef100_C3Z1Q7 DNA topoisomerase n=1 Tax=Branchiostoma floridae RepID=C3Z1Q7_BRAFL
Length = 858
Score = 145 bits (365), Expect(2) = 6e-41
Identities = 73/134 (54%), Positives = 90/134 (67%), Gaps = 3/134 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + +RKG + VHE+ GKF G FK+TSV GHV S
Sbjct: 4 VLMVAEKPSLAQSIAQILSGGSLKSRKGINGACSVHEYTGKFHGESVKFKMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF G Y +W DP DLF+A K E+NP + + L E RG LVLWLDCD+EGEN
Sbjct: 64 LDFQGVYNNWDRVDPADLFRAPTNKKEANPNLKMPKFLELEGRGADILVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVN 470
ICFEVI + ++N
Sbjct: 124 ICFEVIDAVRPSMN 137
Score = 47.0 bits (110), Expect(2) = 6e-41
Identities = 20/38 (52%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YR++FS++TE D+ A+ L PN +EA++VDARQE+D
Sbjct: 147 YRSKFSAITETDIRGAMMRLGEPNENEAMSVDARQELD 184
[65][TOP]
>UniRef100_UPI0000EB0474 DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III
beta- 1). n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB0474
Length = 863
Score = 143 bits (361), Expect(2) = 8e-41
Identities = 71/130 (54%), Positives = 90/130 (69%), Gaps = 5/130 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G M + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGNMSSHKGLNGTCSVHEYSGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDF-PGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+DF GKY W DP +LF QA K E+NPK ++ + L E +GC ++VLWLDCD+EG
Sbjct: 64 LDFLVGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGKGCDYIVLWLDCDKEG 123
Query: 423 ENICFEVIQS 452
ENICFEV+ +
Sbjct: 124 ENICFEVLDA 133
Score = 48.1 bits (113), Expect(2) = 8e-41
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +1
Query: 433 VLRLYNQLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
VL + N S +RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 134 VLPVMNPTHSGEKTVFRARFSSITDTDICAAMARLGEPDHNEALSVDARQELD 186
[66][TOP]
>UniRef100_B4PYQ9 DNA topoisomerase n=1 Tax=Drosophila yakuba RepID=B4PYQ9_DROYA
Length = 878
Score = 141 bits (355), Expect(2) = 1e-40
Identities = 70/144 (48%), Positives = 95/144 (65%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPA-HFKVTSVIGHVF 245
VLMVAEKPS+A S+A +LS+G+ ++G+ HE+ G F + HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP++LF K E+NPK H+ L EARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYNSWDKVDPVELFGCPTEKKETNPKQHMRTFLAHEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +++V S V +
Sbjct: 124 NICFEVMDAVQHVIHNVYSKQVTY 147
Score = 50.1 bits (118), Expect(2) = 1e-40
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITEKDIKGAMETLGHPNENEAKSVDARQELD 184
[67][TOP]
>UniRef100_A8PGM1 DNA topoisomerase n=1 Tax=Brugia malayi RepID=A8PGM1_BRUMA
Length = 858
Score = 140 bits (352), Expect(2) = 1e-40
Identities = 71/133 (53%), Positives = 91/133 (68%), Gaps = 4/133 (3%)
Frame = +3
Query: 66 MAP-KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEV---HEFEGKFLGSPAHFKVTSVI 233
MAP V+MVAEKP +A SIA +L+ G++ RKG V E+ G+F G A FKVTS
Sbjct: 1 MAPLTVMMVAEKPMLAESIAKILADGKVEKRKGWNNVCSVSEYCGQFQGQSAIFKVTSTC 60
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ S+DFP K +W DP+ LF + K E+NPK + +L EA+GC FLVLWLDCD
Sbjct: 61 GHIMSLDFPPKMNNWEKVDPVMLFSSSTAKKEANPKMRMNEYLASEAKGCDFLVLWLDCD 120
Query: 414 REGENICFEVIQS 452
+EGENICFEVI++
Sbjct: 121 KEGENICFEVIEA 133
Score = 51.2 bits (121), Expect(2) = 1e-40
Identities = 23/38 (60%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T KD+ A+ NL RPN +E+L+VDARQE+D
Sbjct: 151 YRAHFSAITAKDIKSAMRNLGRPNINESLSVDARQELD 188
[68][TOP]
>UniRef100_UPI000186CF58 DNA topoisomerase 3-beta, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186CF58
Length = 852
Score = 140 bits (354), Expect(2) = 1e-40
Identities = 66/127 (51%), Positives = 90/127 (70%), Gaps = 3/127 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKPS+A S+A++LS+G+ TRKG + VHE+ G F P F++TSV GH+ ++
Sbjct: 5 LMVAEKPSLAASLANILSNGKSSTRKGFNGACSVHEWVGTFRMEPVTFRMTSVCGHIMTL 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
+F GKY +W DP++L K E+N K + L+QEARGC +L+LWLDCD+EGENI
Sbjct: 65 EFSGKYNNWDKVDPVELLSCPTEKKEANSKLKMPYFLSQEARGCDYLILWLDCDKEGENI 124
Query: 432 CFEVIQS 452
CFEVI +
Sbjct: 125 CFEVIHA 131
Score = 50.1 bits (118), Expect(2) = 1e-40
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FS++TEKD+ A NL PN +EA +VDARQE+D
Sbjct: 147 YRAKFSAITEKDIKAAFANLGVPNENEARSVDARQELD 184
[69][TOP]
>UniRef100_B3NXQ6 DNA topoisomerase n=1 Tax=Drosophila erecta RepID=B3NXQ6_DROER
Length = 878
Score = 140 bits (353), Expect(2) = 2e-40
Identities = 70/144 (48%), Positives = 94/144 (65%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPA-HFKVTSVIGHVF 245
VLMVAEKPS+A S+A +LS+G+ ++G+ HE+ G F + HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP+ LF K E+NPK H+ L EARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYNSWDKVDPVQLFGCPTEKKETNPKQHMRTFLAHEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +++V S V +
Sbjct: 124 NICFEVMDAVQHVIHNVYSKQVTY 147
Score = 50.1 bits (118), Expect(2) = 2e-40
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITEKDIKGAMETLGHPNENEAKSVDARQELD 184
[70][TOP]
>UniRef100_UPI0000519E23 PREDICTED: similar to DNA topoisomerase 3-beta-1 (DNA topoisomerase
III beta-1) isoform 2 n=1 Tax=Apis mellifera
RepID=UPI0000519E23
Length = 851
Score = 135 bits (340), Expect(2) = 2e-40
Identities = 68/137 (49%), Positives = 91/137 (66%), Gaps = 3/137 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKPS+A S+A++LS+G+ +RKG S VHE+ G+F +FK+TSV GHV ++
Sbjct: 5 LMVAEKPSLAASLANILSNGRCTSRKGLNGSCSVHEWIGQFRSETVNFKMTSVFGHVMTL 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF GKY +W DP +LF K E+ P+ I L +E C +LVLWLDCD+EGENI
Sbjct: 65 DFIGKYNNWDKVDPAELFSCPTEKKEAVPRLKIPYFLAKEGAHCDYLVLWLDCDKEGENI 124
Query: 432 CFEVIQSTGFNVNDVLS 482
CFEVI + +N L+
Sbjct: 125 CFEVIYAVQQGMNKRLN 141
Score = 55.1 bits (131), Expect(2) = 2e-40
Identities = 24/38 (63%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++TEKD+ AL NL++PN +EA +VDARQE+D
Sbjct: 146 WRARFSAITEKDIKSALVNLIKPNENEAKSVDARQELD 183
[71][TOP]
>UniRef100_B3MQ67 DNA topoisomerase n=1 Tax=Drosophila ananassae RepID=B3MQ67_DROAN
Length = 878
Score = 140 bits (352), Expect(2) = 2e-40
Identities = 69/144 (47%), Positives = 96/144 (66%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPA-HFKVTSVIGHVF 245
VLMVAEKPS+A S+A++LS+G+ ++G+ HE+ G F + HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLAAILSNGRCTAKRGTGNGCSTHEWTGTFRNEGSVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP++LF K E+NPK H+ L EA+GC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYNSWDKVDPVELFSCPTEKKETNPKQHMRTFLAHEAKGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +++V S V +
Sbjct: 124 NICFEVMDAVQNVIHNVYSRQVTY 147
Score = 50.1 bits (118), Expect(2) = 2e-40
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITEKDIKGAMETLGHPNENEAKSVDARQELD 184
[72][TOP]
>UniRef100_Q9U286 DNA topoisomerase n=1 Tax=Caenorhabditis elegans RepID=Q9U286_CAEEL
Length = 855
Score = 142 bits (359), Expect(2) = 2e-40
Identities = 75/146 (51%), Positives = 94/146 (64%), Gaps = 3/146 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIG 236
MAP VLMVAEKP +A SIA++LS+GQ RKG V E++G+F G A FKVTS G
Sbjct: 1 MAPTVLMVAEKPLLADSIANLLSNGQAKKRKGWNGVCSVSEYDGQFNGRAARFKVTSTCG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
HV S+DFP K+ +W DP +L+ A + E+NPK + L EA+ FLVLWLDCD+
Sbjct: 61 HVMSLDFPPKFNNWERVDPAELYSAPTQRIEANPKMKMNEFLASEAKNADFLVLWLDCDK 120
Query: 417 EGENICFEVIQSTGFNVNDVLSCTVF 494
EGENICFEVI D + C +F
Sbjct: 121 EGENICFEVI--------DAVKCAMF 138
Score = 47.4 bits (111), Expect(2) = 2e-40
Identities = 21/38 (55%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A+ NL RP+++ + +VDARQE+D
Sbjct: 149 YRAHFSAITEKDIKAAMRNLGRPDQNMSHSVDARQELD 186
[73][TOP]
>UniRef100_UPI00015B5DD4 PREDICTED: similar to prokaryotic DNA topoisomerase n=1 Tax=Nasonia
vitripennis RepID=UPI00015B5DD4
Length = 852
Score = 138 bits (348), Expect(2) = 2e-40
Identities = 69/126 (54%), Positives = 87/126 (69%), Gaps = 3/126 (2%)
Frame = +3
Query: 84 MVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
MVAEKPS+A S+A++LS+G+ TRKGS VHE+ G+F +FK+TSV GHV S+D
Sbjct: 6 MVAEKPSLAASLANILSNGRCTTRKGSNGSCSVHEWLGQFRSETVNFKMTSVCGHVMSLD 65
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
F GKY +W DP +LF K E+ PK I L +E C +LVLWLDCD+EGENIC
Sbjct: 66 FIGKYNNWDKVDPAELFSCPTEKKEAVPKLKIPSFLAKEGGYCDYLVLWLDCDKEGENIC 125
Query: 435 FEVIQS 452
FEVIQ+
Sbjct: 126 FEVIQA 131
Score = 51.6 bits (122), Expect(2) = 2e-40
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T+KD+ AL NL +PN +EA +VDARQE+D
Sbjct: 146 WRAKFSAITDKDIKAALANLAKPNENEARSVDARQELD 183
[74][TOP]
>UniRef100_B4NCN9 DNA topoisomerase n=1 Tax=Drosophila willistoni RepID=B4NCN9_DROWI
Length = 884
Score = 140 bits (353), Expect(2) = 4e-40
Identities = 69/144 (47%), Positives = 95/144 (65%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPA-HFKVTSVIGHVF 245
VLMVAEKPS+A S+A++LS+G+ ++G+ HE+ G F + HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLANILSNGRCTAKRGTNNGCSTHEWTGNFRNEGSVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP++LF K E+NPK H+ L EARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYNSWDKVDPVELFGCPTEKKETNPKQHMRTFLAHEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + + +V + V +
Sbjct: 124 NICFEVMDAVQHVIRNVYTPQVTY 147
Score = 48.9 bits (115), Expect(2) = 4e-40
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITEKDIKGAMEKLGFPNENEAKSVDARQELD 184
[75][TOP]
>UniRef100_B0ERJ9 DNA topoisomerase n=1 Tax=Entamoeba dispar SAW760
RepID=B0ERJ9_ENTDI
Length = 840
Score = 144 bits (364), Expect(2) = 7e-40
Identities = 75/129 (58%), Positives = 92/129 (71%), Gaps = 3/129 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
+LMVAEKP +A SIA+ LS G + TRKG S VHEF KF G K+TSV GHV++
Sbjct: 3 LLMVAEKPLLAESIANFLSLGPVKTRKGIAPSCPVHEFNCKFKGKITKAKMTSVAGHVYT 62
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+F +Q+WS DP DLF +V+K E+NPK HI HL EA+GC LVLWLDCDREGEN
Sbjct: 63 CEFERAFQNWSV-DPRDLFNCKVIKVEANPKTHIPSHLRNEAKGCNGLVLWLDCDREGEN 121
Query: 429 ICFEVIQST 455
ICFEV+++T
Sbjct: 122 ICFEVMENT 130
Score = 43.9 bits (102), Expect(2) = 7e-40
Identities = 21/38 (55%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FSS+T+KD+ +A ++L +P+ A AVD RQEID
Sbjct: 141 YRALFSSITKKDITEAFNHLGQPDERLAEAVDCRQEID 178
[76][TOP]
>UniRef100_B4JK56 DNA topoisomerase n=1 Tax=Drosophila grimshawi RepID=B4JK56_DROGR
Length = 862
Score = 137 bits (346), Expect(2) = 9e-40
Identities = 70/144 (48%), Positives = 93/144 (64%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRK---GSTEVHEFEGKFLGS-PAHFKVTSVIGHVF 245
VLMVAEKPS+A S+A++LS+G+ K S +E+ G F HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLAAILSNGRCTAAKRGINSCSTYEWSGNFRNEGTVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP++LF K E NPK + L+QEARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYTSWDKVDPVELFGCPTEKKECNPKQQMRTFLSQEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +++V S V +
Sbjct: 124 NICFEVMDAVQHVIHNVYSHNVTY 147
Score = 50.4 bits (119), Expect(2) = 9e-40
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T+KD+ A+D L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITDKDIKGAMDKLGHPNENEAKSVDARQELD 184
[77][TOP]
>UniRef100_B4MAH9 DNA topoisomerase n=1 Tax=Drosophila virilis RepID=B4MAH9_DROVI
Length = 858
Score = 138 bits (348), Expect(2) = 2e-39
Identities = 69/143 (48%), Positives = 93/143 (65%), Gaps = 3/143 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST--EVHEFEGKFLGSPA-HFKVTSVIGHVFS 248
VLMVAEKPS+A S+A +LS+G+ ++G+ HE+ G F + HF++TSV GHV S
Sbjct: 4 VLMVAEKPSLAASLAGILSNGRCTAKRGNNGCSTHEWTGHFRNEGSVHFRMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF KY W DP++LF K E NPK + L EARGC +LVLWLDCD+EGEN
Sbjct: 64 LDFTSKYTSWDKVDPVELFGCTTEKKECNPKQQMRSFLAHEARGCDYLVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVNDVLSCTVFF 497
ICFEV+ + +++V S V +
Sbjct: 124 ICFEVMDAVQHVIHNVYSRNVTY 146
Score = 48.9 bits (115), Expect(2) = 2e-39
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T+KD+ A++ L PN +EA +VDARQE+D
Sbjct: 146 YRAHFSAITDKDIKGAMETLGHPNENEAKSVDARQELD 183
[78][TOP]
>UniRef100_B4L687 DNA topoisomerase n=1 Tax=Drosophila mojavensis RepID=B4L687_DROMO
Length = 858
Score = 137 bits (345), Expect(2) = 2e-39
Identities = 69/143 (48%), Positives = 91/143 (63%), Gaps = 3/143 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST--EVHEFEGKFLGSP-AHFKVTSVIGHVFS 248
VLMVAEKPS+A S+A +LS+G+ ++G+ HE+ G F HF++TSV GHV S
Sbjct: 4 VLMVAEKPSLAASLAGILSNGRCTAKRGNNGCSTHEWTGPFRNEGNVHFRMTSVCGHVMS 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF KY W DP+ LF K E NPK + L EARGC +LVLWLDCD+EGEN
Sbjct: 64 LDFISKYTSWDKVDPVQLFDCPTEKKECNPKQQMRSFLAHEARGCDYLVLWLDCDKEGEN 123
Query: 429 ICFEVIQSTGFNVNDVLSCTVFF 497
ICFEV+ + +++V S V +
Sbjct: 124 ICFEVMDAVQHVIHNVYSTFVTY 146
Score = 50.1 bits (118), Expect(2) = 2e-39
Identities = 21/38 (55%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T+KD+ A+++L PN++EA +VDARQE+D
Sbjct: 146 YRAHFSAITDKDIKGAMESLGHPNKNEAKSVDARQELD 183
[79][TOP]
>UniRef100_Q29HK8 DNA topoisomerase n=2 Tax=pseudoobscura subgroup RepID=Q29HK8_DROPS
Length = 875
Score = 137 bits (346), Expect(2) = 3e-39
Identities = 69/144 (47%), Positives = 94/144 (65%), Gaps = 4/144 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGS-PAHFKVTSVIGHVF 245
VLMVAEKPS+A S+A++LS+G+ ++G+ HE+ G F HF++TSV GHV
Sbjct: 4 VLMVAEKPSLAASLATILSNGRCTVKRGTGNGCSTHEWTGTFRNEGTVHFRMTSVCGHVM 63
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF KY W DP+ LF K E++PK H+ L EARGC +LVLWLDCD+EGE
Sbjct: 64 SLDFISKYNSWDKVDPVQLFGCPTEKKETSPKQHMRTFLAHEARGCDYLVLWLDCDKEGE 123
Query: 426 NICFEVIQSTGFNVNDVLSCTVFF 497
NICFEV+ + +++V S V +
Sbjct: 124 NICFEVMDAVQGVISNVYSKQVTY 147
Score = 48.9 bits (115), Expect(2) = 3e-39
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T+KD+ A++ L PN +EA +VDARQE+D
Sbjct: 147 YRAHFSAITDKDIKGAMETLGHPNENEAKSVDARQELD 184
[80][TOP]
>UniRef100_UPI0000E494EA PREDICTED: similar to MGC53016 protein n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E494EA
Length = 982
Score = 130 bits (327), Expect(2) = 1e-38
Identities = 64/127 (50%), Positives = 85/127 (66%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VLMVAEKP +A S+A +LS G + +R+G + VHE+ G F G A FK+TSV GHV
Sbjct: 3 EVLMVAEKPQLAQSLAKILSQGSLRSRRGMNGACSVHEYTGTFRGQQAKFKMTSVCGHVH 62
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+D ++ +W DPL F A + E+NP H+ + L E +GC +LVLWLDCD+EGE
Sbjct: 63 GLDIHPRFNNWDKVDPL--FAAPTERKEANPNLHMPKFLAIEGKGCDYLVLWLDCDKEGE 120
Query: 426 NICFEVI 446
NICFEVI
Sbjct: 121 NICFEVI 127
Score = 54.3 bits (129), Expect(2) = 1e-38
Identities = 22/40 (55%), Positives = 35/40 (87%)
Frame = +1
Query: 472 MFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RA+FS++T+KD+ +A++ LV PN +EAL+VDARQE+D
Sbjct: 143 VIFRAKFSAITDKDIRQAMNTLVEPNENEALSVDARQELD 182
[81][TOP]
>UniRef100_UPI00017917D4 PREDICTED: similar to predicted protein n=1 Tax=Acyrthosiphon pisum
RepID=UPI00017917D4
Length = 854
Score = 135 bits (341), Expect(2) = 1e-38
Identities = 67/127 (52%), Positives = 85/127 (66%), Gaps = 3/127 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKPS+A S+AS+LS+G+ +RK VHE+ G G P FK+TSV GHV ++
Sbjct: 5 LMVAEKPSLASSLASILSNGRSNSRKSMNSACPVHEWSGTLFGEPVIFKMTSVCGHVMTL 64
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF K+ +W DP +LF K E++PK I L EARG FL+LWLDCD+EGENI
Sbjct: 65 DFNSKFNNWDKVDPEELFSCPTEKKEASPKLRIPAMLASEARGVDFLILWLDCDKEGENI 124
Query: 432 CFEVIQS 452
CFEVI +
Sbjct: 125 CFEVIDA 131
Score = 48.9 bits (115), Expect(2) = 1e-38
Identities = 21/38 (55%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T KD+ A++ L PNR+EA++VDARQE+D
Sbjct: 146 WRAKFSAITAKDIKGAMERLDFPNRNEAMSVDARQELD 183
[82][TOP]
>UniRef100_C4M656 DNA topoisomerase n=1 Tax=Entamoeba histolytica HM-1:IMSS
RepID=C4M656_ENTHI
Length = 840
Score = 139 bits (350), Expect(2) = 3e-38
Identities = 74/129 (57%), Positives = 87/129 (67%), Gaps = 3/129 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
+LMVAEKP +A SIA LS G + TRKG S VHEF KF G K+TSV GHV++
Sbjct: 3 LLMVAEKPFLAESIAKFLSLGPIHTRKGIAPSCLVHEFNCKFKGKITKAKMTSVAGHVYT 62
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+F +Q+WS DP DLF V+K E+NPK I HL EA GC LVLWLDCDREGEN
Sbjct: 63 CEFERAFQNWSV-DPRDLFSCNVIKVEANPKTRIPAHLRNEANGCNGLVLWLDCDREGEN 121
Query: 429 ICFEVIQST 455
ICFEV+ +T
Sbjct: 122 ICFEVMDNT 130
Score = 43.9 bits (102), Expect(2) = 3e-38
Identities = 21/38 (55%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FSS+T+KD+++A ++L P+ A AVD RQEID
Sbjct: 141 YRALFSSITKKDIIEAFNHLGHPDDRLAEAVDCRQEID 178
[83][TOP]
>UniRef100_Q4Q888 DNA topoisomerase III, putative n=1 Tax=Leishmania major
RepID=Q4Q888_LEIMA
Length = 866
Score = 144 bits (362), Expect(2) = 5e-38
Identities = 71/128 (55%), Positives = 90/128 (70%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPS+A SIA++LS+G R + V+E+ G F+GSPA+FKVTS GHVF
Sbjct: 1 MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYPGNFMGSPAYFKVTSTTGHVF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF ++Q+W TD LF A + +++ K + HL EA+GC LVLWLDCDREGE
Sbjct: 61 SCDFTSQHQNWDRTDEEQLFTAPITWKDTSGK--VTHHLEHEAQGCDTLVLWLDCDREGE 118
Query: 426 NICFEVIQ 449
NICFEV+Q
Sbjct: 119 NICFEVMQ 126
Score = 38.5 bits (88), Expect(2) = 5e-38
Identities = 16/38 (42%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T +++ +A NL +PN++ + AV RQE+D
Sbjct: 139 FRAHFSAITAEEIFQAFRNLGKPNKNISDAVTCRQELD 176
[84][TOP]
>UniRef100_D0EG00 DNA topoisomerase III beta n=1 Tax=Leishmania donovani
RepID=D0EG00_LEIDO
Length = 866
Score = 144 bits (362), Expect(2) = 5e-38
Identities = 71/128 (55%), Positives = 90/128 (70%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPS+A SIA++LS+G R + V+E+ G F+GSPA+FKVTS GHVF
Sbjct: 1 MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYTGNFMGSPAYFKVTSTTGHVF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF ++Q+W TD LF A + +++ K + HL EA+GC LVLWLDCDREGE
Sbjct: 61 SCDFTSQHQNWDRTDEEQLFTAPITWKDTSGK--VTHHLEHEAQGCDTLVLWLDCDREGE 118
Query: 426 NICFEVIQ 449
NICFEV+Q
Sbjct: 119 NICFEVMQ 126
Score = 38.5 bits (88), Expect(2) = 5e-38
Identities = 16/38 (42%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T +++ +A NL +PN++ + AV RQE+D
Sbjct: 139 FRAHFSAITAEEIFQAFRNLGKPNKNISDAVTCRQELD 176
[85][TOP]
>UniRef100_A4URT2 Topoisomerase IIIbeta n=3 Tax=Trypanosoma brucei RepID=A4URT2_TRYBB
Length = 841
Score = 145 bits (365), Expect(2) = 5e-38
Identities = 73/137 (53%), Positives = 91/137 (66%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPSIA SIA LS+G+ + V E++G F G+PAHF+VTS GH+F
Sbjct: 1 MVQTVLMVAEKPSIAESIAHHLSNGRTAKHSRALPVFEYDGYFQGAPAHFRVTSTTGHIF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF +YQ W TD LF A V+ E + + RHL EA+GC LVLWLDCDREGE
Sbjct: 61 SCDFTPQYQSWDRTDEESLFGAPVVWREES--GRVSRHLEHEAKGCATLVLWLDCDREGE 118
Query: 426 NICFEVIQSTGFNVNDV 476
NICFEV+Q +++D+
Sbjct: 119 NICFEVMQVVSRSIHDI 135
Score = 37.4 bits (85), Expect(2) = 5e-38
Identities = 16/38 (42%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T + + +A NL +PN++ + AV RQE+D
Sbjct: 139 WRAKFSAITREAITEAFVNLGKPNKNLSDAVSCRQELD 176
[86][TOP]
>UniRef100_A8XYM0 DNA topoisomerase (Fragment) n=1 Tax=Caenorhabditis briggsae
RepID=A8XYM0_CAEBR
Length = 591
Score = 130 bits (327), Expect(2) = 1e-37
Identities = 67/124 (54%), Positives = 83/124 (66%), Gaps = 3/124 (2%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
LMVAEKP +A SIA++LS+GQ RKG V E++G+F G A FKVTS GHV S+
Sbjct: 1 LMVAEKPMLADSIANLLSNGQARKRKGWNGVCSVSEYDGQFNGRNAKFKVTSTCGHVMSL 60
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DFP KY +W DP +L+ A +K E+N K + L EA+ LVLWLDCD+EGENI
Sbjct: 61 DFPSKYNNWERVDPAELYSAPAVKIEANAKMKMNEFLASEAKTADILVLWLDCDKEGENI 120
Query: 432 CFEV 443
CFEV
Sbjct: 121 CFEV 124
Score = 50.8 bits (120), Expect(2) = 1e-37
Identities = 23/38 (60%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ A+ NL RP+++ AL+VDARQE+D
Sbjct: 141 YRAHFSAITEKDLKAAMKNLGRPDQNMALSVDARQELD 178
[87][TOP]
>UniRef100_A4I3Q5 DNA topoisomerase III, putative n=1 Tax=Leishmania infantum
RepID=A4I3Q5_LEIIN
Length = 867
Score = 142 bits (359), Expect(2) = 2e-37
Identities = 70/128 (54%), Positives = 90/128 (70%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPS+A SIA++LS+G R + V+E+ G F+GSPA+FKVTS GHVF
Sbjct: 1 MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYTGNFMGSPAYFKVTSTTGHVF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF ++Q+W TD LF A + +++ K + HL E++GC LVLWLDCDREGE
Sbjct: 61 SCDFTSQHQNWDRTDEEQLFTAPITWKDTSGK--VSHHLEHESQGCDTLVLWLDCDREGE 118
Query: 426 NICFEVIQ 449
NICFEV+Q
Sbjct: 119 NICFEVMQ 126
Score = 37.7 bits (86), Expect(2) = 2e-37
Identities = 16/38 (42%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T +++ A NL +PN++ + AV RQE+D
Sbjct: 139 FRAHFSAITAEEIFHAFRNLGKPNKNISDAVTCRQELD 176
[88][TOP]
>UniRef100_A4HGN1 DNA topoisomerase III, putative n=1 Tax=Leishmania braziliensis
RepID=A4HGN1_LEIBR
Length = 866
Score = 142 bits (359), Expect(2) = 5e-37
Identities = 70/128 (54%), Positives = 90/128 (70%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPS+A SIA++LS G R + V+E+ G F+GSPA+FKVTS GHVF
Sbjct: 1 MGRNVLMVAEKPSLAESIATILSSGSCSRRTRALPVYEYMGSFMGSPAYFKVTSTTGHVF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF ++Q+W T+ LF A ++ +++ K + HL EA+GC LVLWLDCDREGE
Sbjct: 61 SCDFTSQHQNWDRTEEEQLFTAPIVWKDTSEK--VTHHLEHEAKGCDTLVLWLDCDREGE 118
Query: 426 NICFEVIQ 449
NICFEV+Q
Sbjct: 119 NICFEVMQ 126
Score = 36.2 bits (82), Expect(2) = 5e-37
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T +++ A +L RPN+ + AV RQE+D
Sbjct: 139 FRAHFSAITAEEIFHAFCSLGRPNKSISDAVTCRQELD 176
[89][TOP]
>UniRef100_UPI00006CAF66 DNA topoisomerase family protein n=1 Tax=Tetrahymena thermophila
RepID=UPI00006CAF66
Length = 1386
Score = 135 bits (341), Expect(2) = 1e-36
Identities = 70/126 (55%), Positives = 82/126 (65%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPSIA SIA L TRKG + V F G G A KVTSVIGH+++
Sbjct: 244 VLMVAEKPSIARSIAEALGGAGFTTRKGICKFSNVFTFYGHIFGKKALIKVTSVIGHIYT 303
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
DF +YQDW DP LF A LK E+NP + I +HL +EA G +L+LWLD DREGEN
Sbjct: 304 SDFTQEYQDWRRVDPYKLFNATTLKKETNPNSQIIQHLQKEAMGASYLILWLDNDREGEN 363
Query: 429 ICFEVI 446
ICFEV+
Sbjct: 364 ICFEVL 369
Score = 42.0 bits (97), Expect(2) = 1e-36
Identities = 22/39 (56%), Positives = 29/39 (74%), Gaps = 1/39 (2%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNL-VRPNRDEALAVDARQEID 591
+RA+FSS+T D+ KA D L + PN +E+ AVDARQ ID
Sbjct: 385 FRAKFSSITPIDIRKAFDELSIGPNFNESQAVDARQIID 423
[90][TOP]
>UniRef100_Q24DD8 DNA topoisomerase n=1 Tax=Tetrahymena thermophila SB210
RepID=Q24DD8_TETTH
Length = 1374
Score = 138 bits (347), Expect(2) = 4e-36
Identities = 67/126 (53%), Positives = 91/126 (72%), Gaps = 3/126 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KV+M+AEKPSIA SIA LS+ + KG ++ VHEFEG+F G+ FKVTSV GHV+
Sbjct: 536 KVVMIAEKPSIAKSIADALSNNSSKSVKGYSKYLPVHEFEGQFKGNRVLFKVTSVAGHVY 595
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S+DF +Y W+ +P++LF A+ +K E+NP + +HL +EA+ +L+LWLD DREGE
Sbjct: 596 SLDFQKEYDQWNKVNPINLFSAKTIKVEANPSQGVVKHLEKEAQDASYLILWLDNDREGE 655
Query: 426 NICFEV 443
NICFEV
Sbjct: 656 NICFEV 661
Score = 37.7 bits (86), Expect(2) = 4e-36
Identities = 20/38 (52%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRP-NRDEALAVDARQEID 591
RA+FSS+T+ D+++A N+ P N +E+ AVDARQ ID
Sbjct: 680 RAKFSSLTKSDLVQAFKNVRDPPNMNESKAVDARQIID 717
[91][TOP]
>UniRef100_Q4DXC5 DNA topoisomerase III, putative n=1 Tax=Trypanosoma cruzi
RepID=Q4DXC5_TRYCR
Length = 852
Score = 140 bits (352), Expect(2) = 4e-36
Identities = 73/137 (53%), Positives = 91/137 (66%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVF 245
M VLMVAEKPS+A SIA LS+GQ R + V+E+ G F +PA+FKVTS GHVF
Sbjct: 1 MGRTVLMVAEKPSLAESIAFHLSNGQAAKRSRALPVYEYSGYFFNTPAYFKVTSTTGHVF 60
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S DF ++Q W T+ DLF A V+ + K + RHL EA GC LVLWLDCDREGE
Sbjct: 61 SCDFTPQHQSWDRTEEEDLFSAPVVWKDEAGK--VSRHLAHEAEGCDTLVLWLDCDREGE 118
Query: 426 NICFEVIQSTGFNVNDV 476
NICFEV+Q +++D+
Sbjct: 119 NICFEVMQVVRRSIHDM 135
Score = 35.8 bits (81), Expect(2) = 4e-36
Identities = 15/38 (39%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS++T +++ A +L +PN++ + AV RQE+D
Sbjct: 139 WRAKFSAITREEITHAFLHLGKPNKNVSDAVTCRQELD 176
[92][TOP]
>UniRef100_C1M078 Prokaryotic DNA topoisomerase, putative n=1 Tax=Schistosoma mansoni
RepID=C1M078_SCHMA
Length = 1159
Score = 129 bits (325), Expect(2) = 5e-36
Identities = 63/126 (50%), Positives = 83/126 (65%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
V MVAEKPS+A SIA LS+ + +R+G + +HE+ G+F+ FK+TSV GHV +
Sbjct: 318 VFMVAEKPSLAESIAKSLSNKRNSSRRGFNGACSIHEWTGQFMSEQVRFKMTSVCGHVMN 377
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
VDF +Y W DP +LF A + K E+NPK + L EA+ L+LWLDCD+EGEN
Sbjct: 378 VDFLSRYNSWDKVDPAELFVAPIEKKEANPKLKMVDFLRHEAKNAGILILWLDCDKEGEN 437
Query: 429 ICFEVI 446
ICFEVI
Sbjct: 438 ICFEVI 443
Score = 45.8 bits (107), Expect(2) = 5e-36
Identities = 21/37 (56%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS+VT++++ A+ NL PN+ EAL+VDARQE+D
Sbjct: 458 RAHFSAVTDQELHGAMKNLREPNKHEALSVDARQELD 494
[93][TOP]
>UniRef100_UPI0001509E74 DNA topoisomerase family protein n=1 Tax=Tetrahymena thermophila
RepID=UPI0001509E74
Length = 858
Score = 132 bits (331), Expect(2) = 9e-36
Identities = 69/125 (55%), Positives = 83/125 (66%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
+VLMVAEKPSIA +IA LS R+ + EVH F F P KVTSV+GH+FS D
Sbjct: 7 QVLMVAEKPSIARTIAQALSQQVHTQRRNNHEVHFFPSYFFQMPCLIKVTSVVGHIFSTD 66
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
F +Y + DP+ LF A +K S+P + I +HL EA+GC FLVLWLD DREGENIC
Sbjct: 67 FSPEYNG-NDVDPIKLFDAPTIKKFSSPSSTIIQHLKNEAQGCNFLVLWLDNDREGENIC 125
Query: 435 FEVIQ 449
FEVIQ
Sbjct: 126 FEVIQ 130
Score = 42.7 bits (99), Expect(2) = 9e-36
Identities = 19/39 (48%), Positives = 32/39 (82%), Gaps = 1/39 (2%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLV-RPNRDEALAVDARQEID 591
+RA+FSS+T+ D++KA + L+ P+ +++LAVDARQ +D
Sbjct: 147 FRAKFSSITQVDIIKAYEQLIAEPDLNQSLAVDARQILD 185
[94][TOP]
>UniRef100_UPI000194D401 PREDICTED: topoisomerase (DNA) III beta n=1 Tax=Taeniopygia guttata
RepID=UPI000194D401
Length = 837
Score = 120 bits (301), Expect(2) = 1e-35
Identities = 54/99 (54%), Positives = 69/99 (69%), Gaps = 1/99 (1%)
Frame = +3
Query: 159 GSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLF-QAQVLKNESN 335
G+ VHE+ G F+G AHFK+TSV GHV ++DF GKY W DP +LF +A K E+N
Sbjct: 9 GACSVHEYTGSFIGQSAHFKMTSVCGHVMTLDFIGKYNSWDKVDPAELFSKAPTEKKEAN 68
Query: 336 PKAHICRHLNQEARGCRFLVLWLDCDREGENICFEVIQS 452
PK + + L E RGC +VLWLDCD+EGENICFEV+ +
Sbjct: 69 PKLTMVKFLQVEGRGCDCIVLWLDCDKEGENICFEVLDA 107
Score = 53.9 bits (128), Expect(2) = 1e-35
Identities = 23/38 (60%), Positives = 33/38 (86%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A+++L PNR+EAL+VDARQE+D
Sbjct: 123 YRAKFSSITDTDICNAMNHLGEPNRNEALSVDARQELD 160
[95][TOP]
>UniRef100_UPI000175F71F PREDICTED: similar to topoisomerase (DNA) III beta, partial n=1
Tax=Danio rerio RepID=UPI000175F71F
Length = 199
Score = 122 bits (305), Expect(2) = 1e-35
Identities = 60/124 (48%), Positives = 81/124 (65%), Gaps = 9/124 (7%)
Frame = +3
Query: 108 ALSIASVLSH-----GQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFSVDFPG 263
++S+ +L H G TRKG + VHE+ G F G FK+TSV GHV S+DF G
Sbjct: 14 SISLVDLLRHSDFSSGSCSTRKGLNGACSVHEYMGSFTGQNVRFKMTSVCGHVMSLDFIG 73
Query: 264 KYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICFE 440
KY +W DP +LF +A K E+NPK ++ + L EA+GC ++VLWLDCD+EGENICFE
Sbjct: 74 KYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEAKGCDYVVLWLDCDKEGENICFE 133
Query: 441 VIQS 452
V+ +
Sbjct: 134 VLDA 137
Score = 52.4 bits (124), Expect(2) = 1e-35
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PN++EAL+VDARQE+D
Sbjct: 153 YRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELD 190
[96][TOP]
>UniRef100_Q016P5 Myosin class 11-1 (ISS) n=1 Tax=Ostreococcus tauri RepID=Q016P5_OSTTA
Length = 2117
Score = 126 bits (317), Expect(2) = 3e-35
Identities = 72/143 (50%), Positives = 94/143 (65%), Gaps = 4/143 (2%)
Frame = +3
Query: 36 EAETS*IETKMAPKVLMVAEKPSIALSIASVLSHGQMFT-RKG-STEVHEFEGKFLGSPA 209
++ S +T M+ VL VAEKPS+A IA L+ G FT RKG + +VHEF G+ LG+
Sbjct: 1575 DSTNSSAKTVMSSVVLCVAEKPSLAALIAGFLAPGGAFTTRKGFAGDVHEFTGRGLGTMR 1634
Query: 210 H--FKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGC 383
++VTSV GHV SVDFP ++Q W + DP +LF A +K + RHL EA+G
Sbjct: 1635 SRAWRVTSVKGHVASVDFPERFQSWESCDPGELFAAPTVKRADGK---MVRHLESEAKGA 1691
Query: 384 RFLVLWLDCDREGENICFEVIQS 452
L+LWLDCDREGENICFEVI++
Sbjct: 1692 MTLILWLDCDREGENICFEVIEA 1714
Score = 46.6 bits (109), Expect(2) = 3e-35
Identities = 23/37 (62%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+VT+ V A+ +L R NR+EALAVDARQE+D
Sbjct: 1731 RAKFSAVTKDSVENAMKSLGRANRNEALAVDARQELD 1767
[97][TOP]
>UniRef100_UPI000180D153 PREDICTED: similar to topoisomerase (DNA) III beta, partial n=1
Tax=Ciona intestinalis RepID=UPI000180D153
Length = 827
Score = 125 bits (315), Expect(2) = 1e-34
Identities = 56/92 (60%), Positives = 67/92 (72%)
Frame = +3
Query: 171 VHEFEGKFLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHI 350
VHEF GKF G FKVTSV GHV S+DF GKY +W DP +LF A +K E+NPK +I
Sbjct: 11 VHEFTGKFKGETVRFKVTSVCGHVMSIDFEGKYNNWEKVDPGELFSAPTIKKEANPKLNI 70
Query: 351 CRHLNQEARGCRFLVLWLDCDREGENICFEVI 446
+ L +EAR ++VLWLDCDREGENICFEV+
Sbjct: 71 IKFLEKEARDADYIVLWLDCDREGENICFEVL 102
Score = 45.1 bits (105), Expect(2) = 1e-34
Identities = 18/38 (47%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T+KD+ AL+++ +PN +E+ VDARQ++D
Sbjct: 120 FRAHFSAITDKDINAALNSVGKPNENESQCVDARQDLD 157
[98][TOP]
>UniRef100_C9J248 Putative uncharacterized protein TOP3B n=3 Tax=Homo sapiens
RepID=C9J248_HUMAN
Length = 129
Score = 144 bits (364), Expect = 4e-33
Identities = 70/125 (56%), Positives = 87/125 (69%), Gaps = 4/125 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++VLWLDCD+EGE
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGE 123
Query: 426 NICFE 440
NICFE
Sbjct: 124 NICFE 128
[99][TOP]
>UniRef100_A7AST5 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AST5_BABBO
Length = 878
Score = 118 bits (295), Expect(2) = 1e-32
Identities = 65/144 (45%), Positives = 91/144 (63%), Gaps = 18/144 (12%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQ--MFTRKGSTE-------VH---------EFEGKFL 197
PKVL+VAEKP IA ++A+ L Q + RKG +E +H E GKFL
Sbjct: 4 PKVLVVAEKPKIAETLAAHLCTDQRTLLKRKGVSEDIMCDLGIHIISNTCITWECRGKFL 63
Query: 198 GSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEAR 377
+ FKVTS GH++SV F +Y W++T+P++LF +++ E++P + I RHL EA+
Sbjct: 64 STTVDFKVTSTAGHIYSVAFAPRYNCWNSTNPVELFNGEIILEEASPDSKIPRHLASEAK 123
Query: 378 GCRFLVLWLDCDREGENICFEVIQ 449
GC +L+L LD DREGENI FEVI+
Sbjct: 124 GCSYLLLCLDNDREGENIAFEVIR 147
Score = 46.2 bits (108), Expect(2) = 1e-32
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++T D+L+A+DNL PN+ E+ AV ARQ ID
Sbjct: 162 FRARFSALTRADILRAVDNLCDPNKLESDAVRARQTID 199
[100][TOP]
>UniRef100_UPI000175F70D PREDICTED: novel protein similar to vertebrate topoisomerase (DNA)
III beta (TOP3B) n=1 Tax=Danio rerio RepID=UPI000175F70D
Length = 943
Score = 111 bits (277), Expect(2) = 2e-32
Identities = 50/93 (53%), Positives = 66/93 (70%), Gaps = 1/93 (1%)
Frame = +3
Query: 177 EFEGKFLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHIC 353
+F G F G FK+TSV GHV S+DF GKY +W DP +LF +A K E+NPK ++
Sbjct: 70 DFIGNFTGQNVRFKMTSVCGHVMSLDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMV 129
Query: 354 RHLNQEARGCRFLVLWLDCDREGENICFEVIQS 452
+ L EA+GC ++VLWLDCD+EGENICFEV+ +
Sbjct: 130 KFLQVEAKGCDYVVLWLDCDKEGENICFEVLDA 162
Score = 52.4 bits (124), Expect(2) = 2e-32
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PN++EAL+VDARQE+D
Sbjct: 178 YRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELD 215
[101][TOP]
>UniRef100_B4I0C6 DNA topoisomerase n=1 Tax=Drosophila sechellia RepID=B4I0C6_DROSE
Length = 921
Score = 110 bits (276), Expect(2) = 2e-32
Identities = 53/109 (48%), Positives = 71/109 (65%), Gaps = 1/109 (0%)
Frame = +3
Query: 174 HEFEGKFLGSPA-HFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHI 350
HE+ G F + HF++TSV GHV S+DF K+ W DP+ LF K E+NPK ++
Sbjct: 85 HEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKFNCWDKVDPIQLFGCATEKKETNPKQNM 144
Query: 351 CRHLNQEARGCRFLVLWLDCDREGENICFEVIQSTGFNVNDVLSCTVFF 497
+ L EARGC +LVLWLDCD+EGENICFEV+ + +N+V S V +
Sbjct: 145 RKFLANEARGCDYLVLWLDCDKEGENICFEVMDAVKQVINNVYSDQVTY 193
Score = 52.8 bits (125), Expect(2) = 2e-32
Identities = 23/38 (60%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ KA++ L PN +EA +VDARQE+D
Sbjct: 193 YRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELD 230
[102][TOP]
>UniRef100_Q9LVP1 DNA topoisomerase n=1 Tax=Arabidopsis thaliana RepID=Q9LVP1_ARATH
Length = 926
Score = 121 bits (304), Expect(2) = 7e-32
Identities = 61/126 (48%), Positives = 83/126 (65%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VL VAEKPS+A S+A +LS G TR+G + ++ EF+ G P +TSVIGH+
Sbjct: 11 VLNVAEKPSVAKSVAGILSRGTFRTREGRSRYNKIFEFDYAINGQPCRMLMTSVIGHLME 70
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
++F +Y+ W + DP DL+QA V+K+ K I + L +EAR +LVLWLDCDREGEN
Sbjct: 71 LEFADRYRKWHSCDPADLYQAPVMKHVPEDKKDIKKTLEEEARKSDWLVLWLDCDREGEN 130
Query: 429 ICFEVI 446
I FEV+
Sbjct: 131 IAFEVV 136
Score = 40.0 bits (92), Expect(2) = 7e-32
Identities = 20/37 (54%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++ ++D+ +A+ NL PN+ A AVDARQEID
Sbjct: 150 RAHFSALIDRDIHEAVQNLRDPNQLFAEAVDARQEID 186
[103][TOP]
>UniRef100_A4RZ61 DNA topoisomerase n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4RZ61_OSTLU
Length = 863
Score = 112 bits (281), Expect(2) = 2e-31
Identities = 66/146 (45%), Positives = 88/146 (60%), Gaps = 17/146 (11%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQ------MFTRKG-STEVHEFEGKFLGS------- 203
M ++L VAEKPS+A +IA L+ G + R+G +TEVHEF GS
Sbjct: 1 MPTRILCVAEKPSLASAIARTLARGGDGGDRGVVARRGLATEVHEFATAREGSWAFASGT 60
Query: 204 ---PAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEA 374
A ++VTS GHV SV+F +YQ W +P +LF A V+K + HL +EA
Sbjct: 61 RDGRAEWRVTSTTGHVASVEFSARYQAWEGCEPGELFAADVVKRADG---RMVGHLEREA 117
Query: 375 RGCRFLVLWLDCDREGENICFEVIQS 452
RGC +LVL+LDCDREGENICFEV+++
Sbjct: 118 RGCDYLVLFLDCDREGENICFEVMEA 143
Score = 47.8 bits (112), Expect(2) = 2e-31
Identities = 22/37 (59%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+VT + + +A+ L PNR+EALAVDARQE+D
Sbjct: 164 RAKFSAVTRESIERAMRTLGEPNRNEALAVDARQELD 200
[104][TOP]
>UniRef100_C7J0A2 Os03g0165000 protein n=1 Tax=Oryza sativa Japonica Group
RepID=C7J0A2_ORYSJ
Length = 928
Score = 117 bits (294), Expect(2) = 3e-31
Identities = 64/131 (48%), Positives = 84/131 (64%), Gaps = 5/131 (3%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSH--GQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVI 233
A +VL VAEKPS+A S+A +LS G M +R+G + V EF+ G H VTSV
Sbjct: 9 AIRVLNVAEKPSVAKSVAEILSRPSGGMRSREGRSRYNRVFEFDYSIGGRACHMLVTSVT 68
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ ++F +++ W + DP DLF A V K+ K I R L +EAR C++LVLWLDCD
Sbjct: 69 GHLMELEFDDRFRRWHSCDPADLFHAPVRKSVPQDKQDIKRTLEEEARKCQWLVLWLDCD 128
Query: 414 REGENICFEVI 446
REGENI +EVI
Sbjct: 129 REGENIAYEVI 139
Score = 42.0 bits (97), Expect(2) = 3e-31
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++ ++++ +A+ +L RPN+ A AVDARQEID
Sbjct: 152 WRARFSALIDREIHEAVQHLDRPNKLFADAVDARQEID 189
[105][TOP]
>UniRef100_A2BE48 DNA topoisomerase (Fragment) n=1 Tax=Danio rerio RepID=A2BE48_DANRE
Length = 870
Score = 107 bits (266), Expect(2) = 4e-31
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +3
Query: 192 FLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQ 368
F G FK+TSV GHV S+DF GKY +W DP +LF +A K E+NPK ++ + L
Sbjct: 2 FTGQNVRFKMTSVCGHVMSLDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQV 61
Query: 369 EARGCRFLVLWLDCDREGENICFEVIQS 452
EA+GC ++VLWLDCD+EGENICFEV+ +
Sbjct: 62 EAKGCDYVVLWLDCDKEGENICFEVLDA 89
Score = 52.4 bits (124), Expect(2) = 4e-31
Identities = 22/38 (57%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ A++ L PN++EAL+VDARQE+D
Sbjct: 105 YRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELD 142
[106][TOP]
>UniRef100_A9U3P7 DNA topoisomerase n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9U3P7_PHYPA
Length = 915
Score = 118 bits (296), Expect(2) = 6e-31
Identities = 59/127 (46%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEKPS+A S+A +LS G + TR G + ++ EF G +TSV GH+
Sbjct: 6 RVLNVAEKPSVAKSVAVILSRGNVRTRNGRSVYNKIFEFGYTIGGQQCDMLMTSVTGHLM 65
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF +++ W + DP+DLFQA V K K ++ + L +EAR C++LVLWLDCDREGE
Sbjct: 66 ELDFEDQFRKWHSCDPVDLFQAPVRKKVPQDKVNLQKTLEEEARHCQWLVLWLDCDREGE 125
Query: 426 NICFEVI 446
NI +EV+
Sbjct: 126 NIAYEVV 132
Score = 40.0 bits (92), Expect(2) = 6e-31
Identities = 19/38 (50%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++ ++++ A+ +L RPN+ A AVDARQEID
Sbjct: 145 WRAHFSALIDREIHHAVQHLGRPNKMYADAVDARQEID 182
[107][TOP]
>UniRef100_B7FQA8 DNA topoisomerase (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
1055/1 RepID=B7FQA8_PHATR
Length = 868
Score = 113 bits (282), Expect(2) = 6e-31
Identities = 65/134 (48%), Positives = 85/134 (63%), Gaps = 11/134 (8%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFT-----RKGSTEVHEFEG--KFLGSP--AHF--KVT 224
+L VAEKPSIA +IA L+ + + R S V+E F +P HF K+T
Sbjct: 3 ILHVAEKPSIAQAIAHGLASAEGKSSNPSMRSKSLPVYELSNGISFPKAPHAKHFQHKIT 62
Query: 225 SVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWL 404
SV GHVF+VDFP KYQ W + DP +LF+A +++ K+ + RHL EARG F+VLW+
Sbjct: 63 SVAGHVFNVDFPEKYQSWDSVDPAELFEAPIVRKPC--KSSVVRHLEDEARGVHFIVLWM 120
Query: 405 DCDREGENICFEVI 446
DCDREGENI FEV+
Sbjct: 121 DCDREGENINFEVL 134
Score = 45.4 bits (106), Expect(2) = 6e-31
Identities = 19/38 (50%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++ D+ KA ++L +P++++AL+VDARQE+D
Sbjct: 153 YRAYFSAINPSDIQKAYNSLGKPDKNQALSVDARQELD 190
[108][TOP]
>UniRef100_B8BDG8 DNA topoisomerase n=1 Tax=Oryza sativa Indica Group
RepID=B8BDG8_ORYSI
Length = 897
Score = 117 bits (294), Expect(2) = 2e-30
Identities = 64/131 (48%), Positives = 84/131 (64%), Gaps = 5/131 (3%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSH--GQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVI 233
A +VL VAEKPS+A S+A +LS G M +R+G + V EF+ G H VTSV
Sbjct: 9 AIRVLNVAEKPSVAKSVAEILSRPSGGMRSREGRSRYNRVFEFDYSIGGRACHMLVTSVT 68
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ ++F +++ W + DP DLF A V K+ K I R L +EAR C++LVLWLDCD
Sbjct: 69 GHLMELEFDDRFRRWHSCDPADLFHAPVRKSVPQDKQDIKRTLEEEARKCQWLVLWLDCD 128
Query: 414 REGENICFEVI 446
REGENI +EVI
Sbjct: 129 REGENIAYEVI 139
Score = 38.9 bits (89), Expect(2) = 2e-30
Identities = 19/38 (50%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++ ++++ +A+ +L RPN+ A AVDARQEID
Sbjct: 152 WRACFSALIDREIHEAVQHLDRPNKLFADAVDARQEID 189
[109][TOP]
>UniRef100_C5WWW3 DNA topoisomerase n=1 Tax=Sorghum bicolor RepID=C5WWW3_SORBI
Length = 860
Score = 115 bits (287), Expect(2) = 4e-30
Identities = 62/136 (45%), Positives = 85/136 (62%), Gaps = 4/136 (2%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGH 239
A +VL VAEKPS+A ++A +LS M +R G ++ + EF G H VTSV GH
Sbjct: 8 AIRVLNVAEKPSVAKAVAEILSRRSMQSRAGRSQYNRIFEFNYAINGRACHMLVTSVTGH 67
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ ++F +++ W + DP +LF A V K+ K I + L +EAR C++LVLWLDCDRE
Sbjct: 68 LMELEFDERFRRWHSCDPAELFHAPVRKSVPQDKQAIKQTLEEEARRCQWLVLWLDCDRE 127
Query: 420 GENICFEVIQ-STGFN 464
GENI +EVI TG N
Sbjct: 128 GENIAYEVIDVCTGAN 143
Score = 40.8 bits (94), Expect(2) = 4e-30
Identities = 19/38 (50%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++ ++++ +++ +L RPN+ A AVDARQEID
Sbjct: 149 WRARFSALIDREIHESVQHLGRPNKLFADAVDARQEID 186
[110][TOP]
>UniRef100_B9SN22 DNA topoisomerase (Fragment) n=1 Tax=Ricinus communis
RepID=B9SN22_RICCO
Length = 833
Score = 114 bits (284), Expect(2) = 7e-30
Identities = 59/129 (45%), Positives = 81/129 (62%), Gaps = 6/129 (4%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMF---TRKGST---EVHEFEGKFLGSPAHFKVTSVIGH 239
VL VAEKPS+A S+A++LS Q R+G + ++ EF G H VTSV GH
Sbjct: 4 VLNVAEKPSVAKSVATILSRNQQHGLRVREGQSRYNKIFEFNYVINGQNCHMLVTSVTGH 63
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ ++F +++ W + DP DL+ A V K K +I R L +EAR C++L+LWLDCDRE
Sbjct: 64 LMELEFDDRFRKWHSCDPADLYHAPVRKFVPEDKTNIKRTLEEEARRCQWLILWLDCDRE 123
Query: 420 GENICFEVI 446
GENI FEV+
Sbjct: 124 GENIAFEVV 132
Score = 41.2 bits (95), Expect(2) = 7e-30
Identities = 20/37 (54%), Positives = 29/37 (78%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS++ ++++ +A NLV PN+ + AVDARQEID
Sbjct: 146 RARFSALIDREIHEAAQNLVSPNQWFSDAVDARQEID 182
[111][TOP]
>UniRef100_B4R5E8 DNA topoisomerase n=1 Tax=Drosophila simulans RepID=B4R5E8_DROSI
Length = 821
Score = 102 bits (254), Expect(2) = 7e-30
Identities = 48/93 (51%), Positives = 62/93 (66%)
Frame = +3
Query: 219 VTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVL 398
+TSV GHV S+DF KY W DP+ LF K E+NPK ++ + L EARGC +LVL
Sbjct: 1 MTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLANEARGCDYLVL 60
Query: 399 WLDCDREGENICFEVIQSTGFNVNDVLSCTVFF 497
WLDCD+EGENICFEV+ + +N+V S V +
Sbjct: 61 WLDCDKEGENICFEVMDAVKQVINNVYSDQVTY 93
Score = 52.8 bits (125), Expect(2) = 7e-30
Identities = 23/38 (60%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++TEKD+ KA++ L PN +EA +VDARQE+D
Sbjct: 93 YRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELD 130
[112][TOP]
>UniRef100_A7QSU2 DNA topoisomerase n=1 Tax=Vitis vinifera RepID=A7QSU2_VITVI
Length = 914
Score = 111 bits (277), Expect(2) = 9e-30
Identities = 59/129 (45%), Positives = 82/129 (63%), Gaps = 4/129 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQ-MFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHV 242
KVL VAEKPS+A ++A++LS Q + R+G + ++ EF G VTSVIGH+
Sbjct: 2 KVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKLFEFNYSIRGQHCQMVVTSVIGHL 61
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
++F +++ W + DP L+ A V K K I R L +EAR C++LVLWLDCDREG
Sbjct: 62 MELEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDCDREG 121
Query: 423 ENICFEVIQ 449
ENI FEV++
Sbjct: 122 ENIAFEVLE 130
Score = 43.5 bits (101), Expect(2) = 9e-30
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS++ ++++ +++ NLVRPN+ A AVD RQEID
Sbjct: 142 WRARFSALIDREIHESVQNLVRPNQLFADAVDVRQEID 179
[113][TOP]
>UniRef100_Q8IDM7 DNA topoisomerase III, putative n=1 Tax=Plasmodium falciparum 3D7
RepID=Q8IDM7_PLAF7
Length = 710
Score = 104 bits (260), Expect(2) = 9e-30
Identities = 56/129 (43%), Positives = 78/129 (60%), Gaps = 3/129 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A SIA +LS G+ K ++ V F+ K + VTSV GH+
Sbjct: 5 KVLNVAEKPSVASSIAEILSKGRPNKIKSCSKYNPVFTFDYKIKNDIWYMYVTSVTGHLT 64
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
F +Y++W TDP +LF A++ K +I +L + ++ C L+LWLDCDREGE
Sbjct: 65 DQKFDDRYKNWHNTDPQELFDAEITVYVEKDKKNIENNLKKYSKECNMLILWLDCDREGE 124
Query: 426 NICFEVIQS 452
+ICFEVI +
Sbjct: 125 HICFEVINA 133
Score = 50.1 bits (118), Expect(2) = 9e-30
Identities = 21/41 (51%), Positives = 34/41 (82%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
++ +RA+FS+VTEKD++ A++NL PN++ A +VD R+EID
Sbjct: 141 LIIHRAQFSAVTEKDIIHAINNLKEPNKNLAYSVDVRREID 181
[114][TOP]
>UniRef100_B3L8C2 DNA topoisomerase III, putative n=1 Tax=Plasmodium knowlesi strain
H RepID=B3L8C2_PLAKH
Length = 661
Score = 102 bits (255), Expect(2) = 2e-28
Identities = 59/133 (44%), Positives = 80/133 (60%), Gaps = 4/133 (3%)
Frame = +3
Query: 66 MAP-KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVI 233
MAP VL VAEKPS+A +IA++LS G+M +K ++ V F + VTSV
Sbjct: 1 MAPIHVLNVAEKPSVASAIANILSRGKMERKKSCSKYNPVFTFNYQRDNETWSMYVTSVT 60
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ F KY++W TDP LF A++ N K I +L + ++ C L+LWLDCD
Sbjct: 61 GHLTEQKFDDKYRNWLNTDPQVLFDAEITIYVENDKKTIENNLKRYSKFCNLLILWLDCD 120
Query: 414 REGENICFEVIQS 452
REGE+ICFEVI +
Sbjct: 121 REGEHICFEVINT 133
Score = 47.8 bits (112), Expect(2) = 2e-28
Identities = 22/37 (59%), Positives = 31/37 (83%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+VTEKD++ A++NL PNR+ A +VD R+EID
Sbjct: 145 RAQFSAVTEKDIIHAINNLKYPNRNLANSVDVRREID 181
[115][TOP]
>UniRef100_Q4T9Y1 Chromosome undetermined SCAF7483, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4T9Y1_TETNG
Length = 241
Score = 97.1 bits (240), Expect(2) = 2e-28
Identities = 56/128 (43%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV-- 251
VLMVAEKPS+A SIA +LS Q +R G +F ++ + + H F V
Sbjct: 4 VLMVAEKPSLAQSIAKILSKEQENSRAGKIIFSQFL-----IYSYCVLFVCLKHRFGVLR 58
Query: 252 --DFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+ KY +W DP +LF +A K E++PK ++ + L EA+GC ++VLWLDCD+EG
Sbjct: 59 TLNSLSKYNNWDKVDPAELFSKAPTEKKEASPKLNMIKFLQAEAKGCHYVVLWLDCDKEG 118
Query: 423 ENICFEVI 446
ENICFEVI
Sbjct: 119 ENICFEVI 126
Score = 53.5 bits (127), Expect(2) = 2e-28
Identities = 24/38 (63%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ KA++ L PN +EALAVDARQE+D
Sbjct: 140 YRAKFSSITDTDICKAMNCLGEPNHNEALAVDARQELD 177
[116][TOP]
>UniRef100_Q7RQG4 DNA topoisomerase iii n=1 Tax=Plasmodium yoelii yoelii
RepID=Q7RQG4_PLAYO
Length = 677
Score = 103 bits (257), Expect(2) = 2e-28
Identities = 56/129 (43%), Positives = 78/129 (60%), Gaps = 3/129 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A +I S+LS G+ +K ++ V F+ K VTSV GH+
Sbjct: 5 KVLNVAEKPSVASAIVSILSKGKSNKKKSYSKYNPVFTFDYKMENETWSMFVTSVTGHLT 64
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
F KY++W+ TDP +LF A++ K I +L + ++ C L+LWLDCDREGE
Sbjct: 65 DQKFDDKYKNWNNTDPHELFDAKITIYIDKDKKPIENNLKKYSKDCNVLILWLDCDREGE 124
Query: 426 NICFEVIQS 452
+ICFEVI +
Sbjct: 125 HICFEVINA 133
Score = 46.6 bits (109), Expect(2) = 2e-28
Identities = 21/41 (51%), Positives = 32/41 (78%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RA+FS+VTEKD+ A++NL PN++ A +VD R+EID
Sbjct: 141 LKIHRAQFSAVTEKDIKYAINNLKSPNKNLAQSVDVRREID 181
[117][TOP]
>UniRef100_A5K8A9 DNA topoisomerase III alpha, putative n=1 Tax=Plasmodium vivax
RepID=A5K8A9_PLAVI
Length = 666
Score = 102 bits (255), Expect(2) = 2e-28
Identities = 59/134 (44%), Positives = 80/134 (59%), Gaps = 3/134 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE---FEGKFLGSPAHFKVTSVIGHVFS 248
VL VAEKPS+A +IA +LS G+M +K ++ + F K VTSV GH+
Sbjct: 6 VLNVAEKPSVASAIADILSRGKMEKKKSCSKYNPLFTFNYKRGHETWSMYVTSVTGHLTE 65
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
F KY++W TDP +LF A++ N K I +L ++ C L+LWLDCDREGE+
Sbjct: 66 QKFDDKYRNWVNTDPQELFDAEITIYVENDKKKIENNLKNYSKFCSLLILWLDCDREGEH 125
Query: 429 ICFEVIQSTGFNVN 470
ICFEVI +T F +N
Sbjct: 126 ICFEVI-NTCFAMN 138
Score = 47.4 bits (111), Expect(2) = 2e-28
Identities = 21/37 (56%), Positives = 31/37 (83%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+VT+KD++ A++NL PNR+ A +VD R+EID
Sbjct: 145 RAQFSAVTQKDIIHAINNLKYPNRNLAYSVDVRREID 181
[118][TOP]
>UniRef100_Q4Y492 DNA topoisomerase III, putative n=1 Tax=Plasmodium chabaudi
RepID=Q4Y492_PLACH
Length = 675
Score = 103 bits (256), Expect(2) = 3e-28
Identities = 56/129 (43%), Positives = 78/129 (60%), Gaps = 3/129 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A +I S+LS G+ +K ++ V F+ K VTSV GH+
Sbjct: 5 KVLNVAEKPSVASAIVSILSKGKSNKKKSYSKYNPVFTFDYKMENETWSMFVTSVTGHLT 64
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
F KY++W+ TDP +LF A++ K I +L + ++ C L+LWLDCDREGE
Sbjct: 65 DQKFDEKYKNWNNTDPHELFDAKITIYIDKDKKPIENNLKKYSKDCNVLILWLDCDREGE 124
Query: 426 NICFEVIQS 452
+ICFEVI +
Sbjct: 125 HICFEVINA 133
Score = 46.6 bits (109), Expect(2) = 3e-28
Identities = 21/41 (51%), Positives = 32/41 (78%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RA+FS+VTEKD+ A++NL PN++ A +VD R+EID
Sbjct: 141 LKIHRAQFSAVTEKDIKYAINNLKSPNKNLAQSVDVRREID 181
[119][TOP]
>UniRef100_C1DZI4 DNA topoisomerase (Fragment) n=1 Tax=Micromonas sp. RCC299
RepID=C1DZI4_9CHLO
Length = 639
Score = 105 bits (263), Expect(2) = 3e-28
Identities = 54/128 (42%), Positives = 79/128 (61%), Gaps = 4/128 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEKPS+A ++ VLS+G R+G+++ + EF +G TSV GHV
Sbjct: 5 RVLNVAEKPSVAKEVSRVLSNGGCTNRRGASQYNAIWEFPYTVMGQRCDMVFTSVTGHVM 64
Query: 246 SVDFPGKYQDWSATDPLDLFQ-AQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+DFP ++ W+ +P +L A+V+K K + +L +EA C +L+LWLDCDREG
Sbjct: 65 GLDFPPSHRGWNTCNPRELIDGARVVKQVDKGKEKVAENLRKEASRCAWLILWLDCDREG 124
Query: 423 ENICFEVI 446
ENI FEV+
Sbjct: 125 ENIAFEVM 132
Score = 43.5 bits (101), Expect(2) = 3e-28
Identities = 21/37 (56%), Positives = 27/37 (72%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+++ DV +AL LV PN E+ AVD RQE+D
Sbjct: 146 RARFSALSHNDVTRALARLVDPNPHESAAVDMRQELD 182
[120][TOP]
>UniRef100_UPI00017B4C4A UPI00017B4C4A related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4C4A
Length = 773
Score = 95.5 bits (236), Expect(2) = 5e-28
Identities = 59/137 (43%), Positives = 80/137 (58%), Gaps = 14/137 (10%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHG------QMFTRKGSTE--VHEFEGKFLGSPAHFKVTSV- 230
VLMVAEKPS+A SIA +LS G F + TE +H + G + V V
Sbjct: 4 VLMVAEKPSLAQSIAKILSKGTCCRSSHKFLQGVCTERLIHAMTTQRHGQTLVYCVLFVC 63
Query: 231 IGHVFSV----DFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLV 395
+ H F V + KY +W DP +LF +A K E++PK ++ + L EA+GC ++V
Sbjct: 64 LKHRFGVLRTLNSLSKYNNWDKVDPAELFSKAPTEKKEASPKLNMIKFLQAEAKGCHYVV 123
Query: 396 LWLDCDREGENICFEVI 446
LWLDCD+EGENICFEV+
Sbjct: 124 LWLDCDKEGENICFEVM 140
Score = 53.5 bits (127), Expect(2) = 5e-28
Identities = 24/38 (63%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FSS+T+ D+ KA++ L PN +EALAVDARQE+D
Sbjct: 160 YRAKFSSITDTDICKAMNCLGEPNHNEALAVDARQELD 197
[121][TOP]
>UniRef100_C9J898 Putative uncharacterized protein TOP3B (Fragment) n=1 Tax=Homo
sapiens RepID=C9J898_HUMAN
Length = 196
Score = 100 bits (250), Expect(2) = 1e-27
Identities = 45/80 (56%), Positives = 58/80 (72%), Gaps = 1/80 (1%)
Frame = +3
Query: 216 KVTSVIGHVFSVDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFL 392
K+TSV GHV ++DF GKY W DP +LF QA K E+NPK ++ + L E RGC ++
Sbjct: 2 KMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYI 61
Query: 393 VLWLDCDREGENICFEVIQS 452
VLWLDCD+EGENICFEV+ +
Sbjct: 62 VLWLDCDKEGENICFEVLDA 81
Score = 47.0 bits (110), Expect(2) = 1e-27
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFSS+T+ D+ A+ L P+ +EAL+VDARQE+D
Sbjct: 97 FRARFSSITDTDICNAMACLGEPDHNEALSVDARQELD 134
[122][TOP]
>UniRef100_A5AL75 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5AL75_VITVI
Length = 1769
Score = 125 bits (313), Expect = 3e-27
Identities = 69/130 (53%), Positives = 77/130 (59%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
K LMVAEKPS ALSI S LS G M TR+ S EV EF G F GS A +KVTS
Sbjct: 461 KFLMVAEKPSSALSIXSALSDGHMSTRRSSIEVXEFNGTFXGSNAQYKVTS--------- 511
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
ESNPKAHIC+ L+QEAR C LVLWLDCDREG+NIC
Sbjct: 512 ------------------------ESNPKAHICKRLSQEARDCGHLVLWLDCDREGDNIC 547
Query: 435 FEVIQSTGFN 464
FEV++ TGF+
Sbjct: 548 FEVVECTGFH 557
[123][TOP]
>UniRef100_C1MJC0 Predicted protein (Fragment) n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MJC0_9CHLO
Length = 639
Score = 100 bits (249), Expect(2) = 4e-27
Identities = 55/128 (42%), Positives = 77/128 (60%), Gaps = 4/128 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEKPS+A ++ VLS+G+ R+G T ++ EFE + G TSV GH+
Sbjct: 5 RVLNVAEKPSVAKEVSRVLSNGRASMREGQTPWNKIWEFEHRVQGQQCRMVFTSVTGHLM 64
Query: 246 SVDFPGKYQDWSATDPLDLFQ-AQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
++DF G + W + +L A V K S+ K +L +EAR +L+LWLDCDREG
Sbjct: 65 NLDFTGGARKWGGINARELIDGAPVEKMVSSGKEKTAENLRREARNAAWLILWLDCDREG 124
Query: 423 ENICFEVI 446
ENI FEV+
Sbjct: 125 ENIAFEVM 132
Score = 45.4 bits (106), Expect(2) = 4e-27
Identities = 21/37 (56%), Positives = 29/37 (78%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+++ DV +AL+ LV PN +E+ AVD RQE+D
Sbjct: 146 RARFSALSHNDVTRALNALVAPNENESKAVDMRQELD 182
[124][TOP]
>UniRef100_Q4Z7C4 DNA topoisomerase n=1 Tax=Plasmodium berghei RepID=Q4Z7C4_PLABE
Length = 674
Score = 99.0 bits (245), Expect(2) = 5e-27
Identities = 56/129 (43%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A +I S+LS G+ +K ++ V F+ K VTSV GH+
Sbjct: 5 KVLNVAEKPSVASAIVSILSKGESNKKKSYSKYNPVFTFDYKMENETWSMFVTSVTGHLT 64
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
F KY++W+ TDP +LF A++ K I +L + ++ C L+LWLDCDREGE
Sbjct: 65 DQKFDDKYKNWNNTDPHELFDAKITIYIDKDKKPIENNLKKYSKDCNVLILWLDCDREGE 124
Query: 426 NICFEVIQS 452
ICFEVI +
Sbjct: 125 -ICFEVINA 132
Score = 46.6 bits (109), Expect(2) = 5e-27
Identities = 21/41 (51%), Positives = 32/41 (78%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RA+FS+VTEKD+ A++NL PN++ A +VD R+EID
Sbjct: 140 LKIHRAQFSAVTEKDIKYAINNLKSPNKNLAQSVDVRREID 180
[125][TOP]
>UniRef100_A0DGW1 DNA topoisomerase n=1 Tax=Paramecium tetraurelia RepID=A0DGW1_PARTE
Length = 949
Score = 112 bits (281), Expect(2) = 6e-27
Identities = 62/137 (45%), Positives = 93/137 (67%), Gaps = 2/137 (1%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
K+LMVAEK SIA ++A + + ++ +KG + F G F G A+F VT+ GH+FS D
Sbjct: 31 KILMVAEKNSIAEAVAYAIGN-KVRAKKGRQAFYYFSGMFKGQQANFTVTATNGHLFSRD 89
Query: 255 FPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENIC 434
FP +Y++W++ DP+DLFQA+ +K +N KA I L + + G +L+LWLD DREGENIC
Sbjct: 90 FPKEYENWNSCDPIDLFQAKTIKKPAN-KAGI-GLLRKCSSGIDYLILWLDNDREGENIC 147
Query: 435 FEV--IQSTGFNVNDVL 479
FEV ++S N+ +++
Sbjct: 148 FEVDEVKSKVINLGNLI 164
Score = 32.3 bits (72), Expect(2) = 6e-27
Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNL-VRPNRDEALAVDARQEID 591
RA+FSS+T+ D+ A + L PN E+ +VDARQ ID
Sbjct: 168 RAKFSSITQTDLKYAYNQLNTGPNILESESVDARQIID 205
[126][TOP]
>UniRef100_Q01CA7 DNA topoisomerase III alpha, putative (ISS) n=1 Tax=Ostreococcus
tauri RepID=Q01CA7_OSTTA
Length = 842
Score = 103 bits (258), Expect(2) = 6e-27
Identities = 57/131 (43%), Positives = 83/131 (63%), Gaps = 5/131 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEKPS+A I+ VLS+G R+G+T +V EFE G P TSV GH+
Sbjct: 6 RVLNVAEKPSVAKEISRVLSNGTARVREGATAWNKVWEFEHVVRGRPVTMVFTSVTGHLS 65
Query: 246 SVDFPG-KYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ +F +++ W++ DP +L A+V+K K ++ +EARGC ++LWLDCDRE
Sbjct: 66 NFEFAEERHRRWASVDPRELLVDARVVKRVPEDKRKTAENVKREARGCDTVILWLDCDRE 125
Query: 420 GENICFEVIQS 452
GENI FEV+++
Sbjct: 126 GENIAFEVLEA 136
Score = 41.2 bits (95), Expect(2) = 6e-27
Identities = 21/37 (56%), Positives = 26/37 (70%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS++ D +AL NLV+PN EA AVD R E+D
Sbjct: 148 RARFSALGRGDADRALANLVQPNEYEAKAVDMRMELD 184
[127][TOP]
>UniRef100_UPI0000586473 PREDICTED: similar to MGC80537 protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000586473
Length = 679
Score = 100 bits (248), Expect(2) = 2e-26
Identities = 57/129 (44%), Positives = 75/129 (58%), Gaps = 3/129 (2%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGH 239
A KVL VAEK A SIA V+SHG+ R+G ++ ++EF+ L +TSV GH
Sbjct: 6 ATKVLNVAEKNDAAKSIADVMSHGRYRRREGFSKFNKIYEFDYSMLNQQCDMTMTSVSGH 65
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ + +F YQ W + +P+ LF A V K I R L +EAR LV+W DCDRE
Sbjct: 66 LLNYEFALAYQKWHSCNPVALFDAPVQKGCPENYKDIKRTLEREARAADVLVIWTDCDRE 125
Query: 420 GENICFEVI 446
GENI +EVI
Sbjct: 126 GENIGYEVI 134
Score = 43.5 bits (101), Expect(2) = 2e-26
Identities = 19/38 (50%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS +T + + +A NLVRP++ + AVD RQ++D
Sbjct: 147 YRARFSEITPQSITRACANLVRPDQRVSQAVDVRQQLD 184
[128][TOP]
>UniRef100_B0EMC7 DNA topoisomerase 3-alpha, putative n=1 Tax=Entamoeba dispar SAW760
RepID=B0EMC7_ENTDI
Length = 607
Score = 102 bits (253), Expect(2) = 2e-26
Identities = 58/129 (44%), Positives = 79/129 (61%), Gaps = 5/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKF--LGSPAHFKVTSVIGHV 242
VL VAEKPS+A +I+ LS GQ G ++ + EFE +F +G H+ VTSV GH+
Sbjct: 4 VLHVAEKPSVANAISYTLSRGQCQKTSGLSKYNSIFEFEKEFKNIGKCTHY-VTSVAGHL 62
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+DF Y+ W + DP +LF A + K+ + +L A+ C+ LVLWLDCDREG
Sbjct: 63 KGIDFTTAYRSWGSCDPEELFTAPIEKSVPASMKKVELNLKNVAKKCQVLVLWLDCDREG 122
Query: 423 ENICFEVIQ 449
ENI FEVI+
Sbjct: 123 ENISFEVIE 131
Score = 41.2 bits (95), Expect(2) = 2e-26
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
M +RA F+S+ +++KA + L PNR + AVD RQEID
Sbjct: 140 MKVWRAHFNSLVPDEIIKAYNTLTAPNRHMSEAVDVRQEID 180
[129][TOP]
>UniRef100_UPI00006CA49A DNA topoisomerase family protein n=1 Tax=Tetrahymena thermophila
RepID=UPI00006CA49A
Length = 916
Score = 122 bits (305), Expect = 3e-26
Identities = 66/129 (51%), Positives = 86/129 (66%), Gaps = 4/129 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL+VAEKPS+A IAS LS+ R+G V+ +EG+F G FKVTSV GHV+
Sbjct: 206 EVLLVAEKPSVARKIASALSNKTSKKRQGKVRYLPVYVYEGRFKGQKTIFKVTSVTGHVY 265
Query: 246 SVDFPGKYQD-WSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+DFP K ++ W+ +P+ LF + LK S K +I RHL EAR C +L+LWLD D+EG
Sbjct: 266 DLDFPQKLKENWNEINPVQLFSSDTLKIPS--KHNIVRHLESEARNCSYLLLWLDNDKEG 323
Query: 423 ENICFEVIQ 449
ENICFEV Q
Sbjct: 324 ENICFEVKQ 332
[130][TOP]
>UniRef100_B9H4K8 DNA topoisomerase n=1 Tax=Populus trichocarpa RepID=B9H4K8_POPTR
Length = 910
Score = 122 bits (305), Expect = 3e-26
Identities = 69/157 (43%), Positives = 91/157 (57%), Gaps = 4/157 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A S+A++LS Q+ R G + ++ EF G H VTSV GH+
Sbjct: 3 KVLNVAEKPSVAKSVATILSRNQLRVRDGRSRYNKIFEFNYSINGQQCHMLVTSVTGHLM 62
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
V+F +++ W + DP DL+ A V K K I R L +EAR C +LVLWLDCDREGE
Sbjct: 63 EVEFEDRFRKWHSCDPADLYTAPVRKYVPEDKLDIKRTLEEEARRCHWLVLWLDCDREGE 122
Query: 426 NICFEVIQ-STGFNVNDVLSCTVFFCY*ERCLEGSRQ 533
NI FEV++ G N N + F ER + + Q
Sbjct: 123 NIAFEVMEVCKGVNRNLTIRRARFSALIERDIHEAAQ 159
[131][TOP]
>UniRef100_UPI0000D56E1B PREDICTED: similar to topoisomerase (DNA) III alpha n=1
Tax=Tribolium castaneum RepID=UPI0000D56E1B
Length = 951
Score = 100 bits (248), Expect(2) = 3e-26
Identities = 51/128 (39%), Positives = 79/128 (61%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+ L VAEK A +IA++LS G R+G + +++EF+ +G AH +TSV GH+
Sbjct: 2 RYLNVAEKNDAAKNIAAILSRGASQRREGFSPYNKIYEFDATVMGQQAHMIMTSVSGHLL 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +F +++W + +P+ LF A V+K I R L +E R C+ L++W DCDREGE
Sbjct: 62 NYEFGPSFRNWKSCNPVALFDAPVVKMCPEDYQKIKRTLEREIRSCQGLIIWTDCDREGE 121
Query: 426 NICFEVIQ 449
NI FE+I+
Sbjct: 122 NIGFEIIK 129
Score = 42.7 bits (99), Expect(2) = 3e-26
Identities = 18/41 (43%), Positives = 29/41 (70%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ YRA+FS +T + +AL+ L +PN++ + AVD RQE+D
Sbjct: 138 LRIYRAKFSEITAASIFRALNTLGQPNKNVSDAVDVRQELD 178
[132][TOP]
>UniRef100_C3Z741 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3Z741_BRAFL
Length = 346
Score = 105 bits (262), Expect(2) = 5e-26
Identities = 59/127 (46%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A +IA VLS+G+ R+G ++ ++EFE L + +TSV GH+
Sbjct: 7 KVLNVAEKNDAAKAIADVLSNGRYRRREGFSKFNKIYEFEFNILNKQSSMSMTSVSGHLL 66
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF G YQ W + P+ LF A V K+ + I R L +EAR C+ LV+W DCDREGE
Sbjct: 67 ELDFKGSYQKWHSCQPVALFDAGVEKHCPDQFKDIKRTLEREARQCQVLVIWTDCDREGE 126
Query: 426 NICFEVI 446
NI EVI
Sbjct: 127 NIGTEVI 133
Score = 36.6 bits (83), Expect(2) = 5e-26
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS T + ++ A NLV+P+ + AV+ R E+D
Sbjct: 146 YRARFSDFTPQSIISACCNLVQPDYRSSDAVNVRSELD 183
[133][TOP]
>UniRef100_UPI0001927315 PREDICTED: similar to topoisomerase (DNA) III beta n=1 Tax=Hydra
magnipapillata RepID=UPI0001927315
Length = 1349
Score = 94.0 bits (232), Expect(2) = 9e-26
Identities = 62/140 (44%), Positives = 78/140 (55%), Gaps = 7/140 (5%)
Frame = +3
Query: 57 ETKMAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE-FEGKFLGSPAHFK----V 221
E + KVL+VAEKPS+A IA LS G TR+G + ++ FE PA K V
Sbjct: 512 ENEQFSKVLIVAEKPSVAKMIAEQLSGGHFRTRRGKSRANQIFEFIKWFGPAQQKCKLMV 571
Query: 222 TSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKN--ESNPKAHICRHLNQEARGCRFLV 395
TSV+GH+F + F G+ D LF A V K +S K +I HL + + +L
Sbjct: 572 TSVVGHIFGLGFAGRPD----RDISKLFDASVEKQLADSTKKLNIVEHLQELGQESEYLF 627
Query: 396 LWLDCDREGENICFEVIQST 455
LWLDCDREGENI FEVI T
Sbjct: 628 LWLDCDREGENIGFEVISLT 647
Score = 47.4 bits (111), Expect(2) = 9e-26
Identities = 21/38 (55%), Positives = 32/38 (84%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS++T+ ++ +A DN VRP++ A++VDARQE+D
Sbjct: 657 YRARFSALTKTELSQAYDNPVRPDKYAAMSVDARQELD 694
[134][TOP]
>UniRef100_UPI0001868BE2 hypothetical protein BRAFLDRAFT_241310 n=1 Tax=Branchiostoma
floridae RepID=UPI0001868BE2
Length = 893
Score = 105 bits (262), Expect(2) = 9e-26
Identities = 59/127 (46%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A +IA VLS+G+ R+G ++ ++EFE L + +TSV GH+
Sbjct: 7 KVLNVAEKNDAAKAIADVLSNGRYRRREGFSKFNKIYEFEFNILNKQSSMSMTSVSGHLL 66
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+DF G YQ W + P+ LF A V K+ + I R L +EAR C+ LV+W DCDREGE
Sbjct: 67 ELDFKGSYQKWHSCQPVALFDAGVEKHCPDQFKDIKRTLEREARQCQVLVIWTDCDREGE 126
Query: 426 NICFEVI 446
NI EVI
Sbjct: 127 NIGTEVI 133
Score = 35.8 bits (81), Expect(2) = 9e-26
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS T + + A NLV+P+ + AV+ R E+D
Sbjct: 146 YRARFSDFTPQSITSACRNLVQPDYRSSDAVNVRSELD 183
[135][TOP]
>UniRef100_A7S883 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S883_NEMVE
Length = 940
Score = 98.6 bits (244), Expect(2) = 1e-25
Identities = 52/127 (40%), Positives = 75/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A ++ ++S GQ R+G + +++EF L + A +TSV GH+
Sbjct: 2 RVLNVAEKNDAAKELSRIMSRGQCTRREGQSRFNKIYEFNFNILNANARMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
S++F Y+ WS+ PL LF A V+KN I + L E RG + L++W DCDREGE
Sbjct: 62 SLEFAIAYRKWSSCSPLSLFDAPVVKNVGEDYLPIKKTLECEVRGSQALIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI E+I
Sbjct: 122 NIGHEII 128
Score = 42.4 bits (98), Expect(2) = 1e-25
Identities = 20/38 (52%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS +T + V +A NLV P+R ++ AVD R E+D
Sbjct: 141 YRARFSEITPQSVQRACANLVAPDRLQSEAVDVRMELD 178
[136][TOP]
>UniRef100_A4RUT1 Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus
CCE9901 RepID=A4RUT1_OSTLU
Length = 641
Score = 97.1 bits (240), Expect(2) = 2e-25
Identities = 54/129 (41%), Positives = 79/129 (61%), Gaps = 5/129 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEKPS+A I+ VLS+G+ R+G++ +V EF + G TSV GH+
Sbjct: 13 RVLNVAEKPSVAKEISRVLSNGRASAREGTSRYNKVWEFPYEVRGRRVTMVFTSVTGHLS 72
Query: 246 SVDFPG-KYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ +F +++ W+ DP +L A V K K + ++ +EARGC ++LWLDCDRE
Sbjct: 73 NFEFADDRHRRWNGVDPRELLVNAAVAKRVPEDKRQVADNVKREARGCDSVILWLDCDRE 132
Query: 420 GENICFEVI 446
GENI FEV+
Sbjct: 133 GENIAFEVL 141
Score = 43.5 bits (101), Expect(2) = 2e-25
Identities = 20/38 (52%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS+++ D +AL NLV PN+ E+ AVD R E+D
Sbjct: 154 FRARFSALSRGDADRALTNLVEPNQHESKAVDMRMELD 191
[137][TOP]
>UniRef100_Q8T2T7 DNA topoisomerase 3 n=1 Tax=Dictyostelium discoideum
RepID=TOP3_DICDI
Length = 828
Score = 95.1 bits (235), Expect(2) = 3e-25
Identities = 49/132 (37%), Positives = 79/132 (59%), Gaps = 4/132 (3%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVH---EFEGKFLG-SPAHFKVTSVI 233
M ++L VAEKPS A IA++LS+ + R+G ++ + +F+ L + TSV
Sbjct: 1 MTKRILNVAEKPSAAKEIAAILSNKRATVREGFSKYNKLWDFKYNILNFNDCEMTFTSVT 60
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ +D +++ W++ DP+ LF A + K + K + + L +E + L+LWLDCD
Sbjct: 61 GHLMEIDVVEQFKPWASCDPIQLFDAPIRKTVPSDKEPLKKTLEREIKKADILILWLDCD 120
Query: 414 REGENICFEVIQ 449
REGENI FEV++
Sbjct: 121 REGENIAFEVLE 132
Score = 44.7 bits (104), Expect(2) = 3e-25
Identities = 18/39 (46%), Positives = 28/39 (71%)
Frame = +1
Query: 475 FYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
FYRA FS++ +++ +A NL +PN +++AVD R EID
Sbjct: 143 FYRAHFSAIIPREIDRACKNLAKPNEKDSIAVDTRMEID 181
[138][TOP]
>UniRef100_A0CUH3 Chromosome undetermined scaffold_28, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CUH3_PARTE
Length = 947
Score = 98.2 bits (243), Expect(2) = 3e-25
Identities = 56/128 (43%), Positives = 78/128 (60%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLS--HGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
KVL VAEKPS+A SIA+VL+ H T+ ++ +F KF +TSV GH+ S
Sbjct: 14 KVLNVAEKPSVARSIANVLARDHTVEETQSPYNKLFKFNFKFGDQEVEMWITSVTGHLKS 73
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNE-SNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +P +YQ W DP+ + + ++N N K + +L Q AR C L+LWLDCDREGE
Sbjct: 74 LRYPKQYQKWDQWDPIIILKDAEIENIIPNEKRFLEGNLKQFARECSQLILWLDCDREGE 133
Query: 426 NICFEVIQ 449
NI FEV++
Sbjct: 134 NIAFEVLE 141
Score = 41.2 bits (95), Expect(2) = 3e-25
Identities = 21/38 (55%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS+VT D+ KALDNL +P+ + + +V ARQEID
Sbjct: 153 HRAHFSAVTYIDIKKALDNLKQPDENLSNSVLARQEID 190
[139][TOP]
>UniRef100_B4JCW0 DNA topoisomerase n=1 Tax=Drosophila grimshawi RepID=B4JCW0_DROGR
Length = 1269
Score = 101 bits (252), Expect(2) = 7e-25
Identities = 55/127 (43%), Positives = 74/127 (58%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS G R+G + +V++FE + G A +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTIAGLLSGGSANRREGYSVYNKVYDFEAQVRGQNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
VDF Y++W DP LF A + K I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QVDFLASYRNWLNVDPRSLFDAPIRKTVGENYEPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 36.6 bits (83), Expect(2) = 7e-25
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRASFSEITTASVRRALQQLGQPDKRQSDAVDVRTELD 178
[140][TOP]
>UniRef100_Q4YF11 Putative uncharacterized protein n=1 Tax=Plasmodium berghei
RepID=Q4YF11_PLABE
Length = 242
Score = 102 bits (254), Expect(2) = 1e-24
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEKPS+A +I S+ S G+ +K ++ V F+ K VTSV GH+
Sbjct: 5 KVLNVAEKPSVASAIVSIFSKGESNKKKSYSKYNPVFTFDYKMENETWSMFVTSVTGHLT 64
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
F KY++W+ TDP +LF A++ K I +L + ++ C L+LWLDCDREGE
Sbjct: 65 DQKFDDKYKNWNNTDPHELFDAKITIYIDKDKKPIENNLKKYSKDCNVLILWLDCDREGE 124
Query: 426 NICFEVIQS 452
+ICFEVI +
Sbjct: 125 HICFEVINA 133
Score = 35.4 bits (80), Expect(2) = 1e-24
Identities = 17/38 (44%), Positives = 26/38 (68%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQ 582
+ +RA+FS+VTEKD+ A++NL N+ A VD R+
Sbjct: 141 LKIHRAQFSAVTEKDIKYAINNLKSQNKILAQRVDVRR 178
[141][TOP]
>UniRef100_B4MYR0 DNA topoisomerase n=1 Tax=Drosophila willistoni RepID=B4MYR0_DROWI
Length = 1234
Score = 101 bits (251), Expect(2) = 1e-24
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +I+ +L++G R+G + +V +FE + G A +TSV GH+
Sbjct: 2 KYLNVAEKNDAAKTISRLLANGAEHRREGYSVYNKVFDFEAQVRGQNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F Y++W DP LF A + K+ A I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLEFQVSYRNWRTVDPRSLFDAPIKKSVGEKYAPIKRTLEREIRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVIQ 449
NI FE+I+
Sbjct: 122 NIGFEIIE 129
Score = 36.2 bits (82), Expect(2) = 1e-24
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L P++ ++ AVD R E+D
Sbjct: 141 YRASFSEITSAAVRRALQQLGEPDKRQSDAVDVRSELD 178
[142][TOP]
>UniRef100_C4LZR4 DNA topoisomerase III, putative n=1 Tax=Entamoeba histolytica
HM-1:IMSS RepID=C4LZR4_ENTHI
Length = 607
Score = 96.7 bits (239), Expect(2) = 2e-24
Identities = 56/129 (43%), Positives = 77/129 (59%), Gaps = 5/129 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFL--GSPAHFKVTSVIGHV 242
+L VAEKPS+A +I+ LS G G ++ V FE +F G H+ VTSV GH+
Sbjct: 4 ILHVAEKPSVASAISYTLSRGTCKKTPGLSKYNSVFSFEHEFKNDGKCTHY-VTSVAGHL 62
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+DF Y+ W + DP +LF A + K+ + + +L A+ C+ LVLWLDCDREG
Sbjct: 63 KGIDFTTAYRSWGSCDPEELFTAPIEKSVPSNMKKVELNLKSLAKKCQVLVLWLDCDREG 122
Query: 423 ENICFEVIQ 449
ENI FEVI+
Sbjct: 123 ENISFEVIE 131
Score = 40.4 bits (93), Expect(2) = 2e-24
Identities = 18/41 (43%), Positives = 27/41 (65%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
M +RA F+S+ +++KA + L PN+ + AVD RQEID
Sbjct: 140 MKVWRAHFNSLVPNEIIKAYNTLTAPNKHMSEAVDVRQEID 180
[143][TOP]
>UniRef100_B3RSB2 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3RSB2_TRIAD
Length = 625
Score = 93.2 bits (230), Expect(2) = 2e-24
Identities = 49/130 (37%), Positives = 77/130 (59%), Gaps = 3/130 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIG 236
M ++L VAEK A S++ ++S G + ++G ++ + EF+ L S +TSV G
Sbjct: 1 MHRRILNVAEKNDAAKSLSRIMSRGNLTKKEGLSKYNKIFEFDFNILNSSCRMVMTSVSG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ S+DF +Q W++ P++LF+AQV K + I + L +E R C L++W D DR
Sbjct: 61 HLLSMDFLSNFQKWNSCLPVELFEAQVQKFCTGTNIPIKKTLEREIRNCNTLIIWTDGDR 120
Query: 417 EGENICFEVI 446
EGENI E+I
Sbjct: 121 EGENIGHEII 130
Score = 43.5 bits (101), Expect(2) = 2e-24
Identities = 18/38 (47%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS +T + +++A +NL RP+ ++ AVD RQE+D
Sbjct: 143 HRARFSEITYRSIMRACENLTRPDNLQSDAVDVRQELD 180
[144][TOP]
>UniRef100_UPI000069F653 DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III
alpha). n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F653
Length = 1021
Score = 97.8 bits (242), Expect(2) = 3e-24
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA ++S+ +M R+G ++ ++E+E G +TSV GH+
Sbjct: 40 KVLCVAEKNDAAKGIADLMSNSRMRRREGFSKFNKIYEYEYHLFGKDVTVVMTSVSGHLL 99
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++DF + W + +P+ LF+A+V K + +I R L +E R C+ L++W DCDREGE
Sbjct: 100 ALDFQDHMKKWHSCNPVSLFEAEVQKYCPDDFVNIKRTLEREVRQCQALIIWTDCDREGE 159
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 160 NIGFEII 166
Score = 38.5 bits (88), Expect(2) = 3e-24
Identities = 16/41 (39%), Positives = 29/41 (70%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T + + A ++LV+P+++ + AVD R E+D
Sbjct: 176 LQVFRARFSEITPRSIRMACEHLVQPDQNISDAVDVRMELD 216
[145][TOP]
>UniRef100_UPI000180B0E3 PREDICTED: similar to topoisomerase (DNA) III alpha, partial n=1
Tax=Ciona intestinalis RepID=UPI000180B0E3
Length = 571
Score = 94.4 bits (233), Expect(2) = 3e-24
Identities = 53/127 (41%), Positives = 71/127 (55%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A I+ +LS Q R G ++ ++EF LG VTS+ GH+
Sbjct: 9 KVLSVAEKNDAAKRISDILSGHQYQVRNGFSKYNKIYEFSYHMLGQNCAMSVTSLSGHLL 68
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +F G Y+ W + PL LF +V K + I R L +E R + LV+W DCDREGE
Sbjct: 69 NYNFAGIYKKWHSCHPLSLFDVEVEKIVTENMVDIKRTLEREVRNSQALVIWTDCDREGE 128
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 129 NIGFEII 135
Score = 42.0 bits (97), Expect(2) = 3e-24
Identities = 18/38 (47%), Positives = 28/38 (73%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS +T++ + A NL +P+++ + AVD RQE+D
Sbjct: 148 YRARFSEITDRSIKSACRNLQQPDQNTSDAVDVRQELD 185
[146][TOP]
>UniRef100_UPI000179272C PREDICTED: similar to topoisomerase (DNA) III alpha n=1
Tax=Acyrthosiphon pisum RepID=UPI000179272C
Length = 839
Score = 102 bits (253), Expect(2) = 4e-24
Identities = 55/127 (43%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A +IA LS G + R+G ++ ++EF F GSP+ +TSV GH+
Sbjct: 2 RVLNVAEKNDAAKNIAGHLSGGNLQRREGFSKFNKIYEFNHTFQGSPSTMIMTSVSGHLL 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+F G Y+ W++ PL+LF V+K N +I + L +E R C LV+W D DREGE
Sbjct: 62 GYEFQGSYRSWTSCSPLELFHIPVVKECPNDFINIKKTLVREIRSCNTLVIWTDADREGE 121
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 122 NIGFEII 128
Score = 33.9 bits (76), Expect(2) = 4e-24
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA S +T V +A+ +L PN++ + AVD R E+D
Sbjct: 141 YRAILSEITRPSVQRAISSLGPPNKNISDAVDVRSELD 178
[147][TOP]
>UniRef100_B4PAZ8 DNA topoisomerase n=1 Tax=Drosophila yakuba RepID=B4PAZ8_DROYA
Length = 1229
Score = 99.8 bits (247), Expect(2) = 5e-24
Identities = 55/127 (43%), Positives = 74/127 (58%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + +V +FE G A +TSV GH+
Sbjct: 2 KYLNVAEKNDAAKTIAGLLSNGAARRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ F Y++W DP LF A V K S+ I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLAFQVSYKNWKTVDPRSLFDAPVKKRVSSDYEPIKRTLEREVRGCQGLIVWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 35.8 bits (81), Expect(2) = 5e-24
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRATFSEITSVAVRRALQQLGQPDKRQSDAVDVRTELD 178
[148][TOP]
>UniRef100_Q29K61 DNA topoisomerase n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=Q29K61_DROPS
Length = 1178
Score = 99.8 bits (247), Expect(2) = 6e-24
Identities = 53/127 (41%), Positives = 75/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + ++++FE G A +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTIAGLLSNGAANRREGYSVYNKIYDFEAPVRGQNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F Y++W DP LF A V K+ I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLEFQVSYRNWRVVDPGSLFDAPVRKSVGESYLPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 35.4 bits (80), Expect(2) = 6e-24
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 138 LTIYRASFSEITTIAVRRALQQLGQPDKRQSDAVDVRTELD 178
[149][TOP]
>UniRef100_B9PMP6 DNA topoisomerase n=1 Tax=Toxoplasma gondii GT1 RepID=B9PMP6_TOXGO
Length = 677
Score = 99.4 bits (246), Expect(2) = 6e-24
Identities = 56/125 (44%), Positives = 72/125 (57%), Gaps = 2/125 (1%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMF--TRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
VL VAEKPS+A + +LS G T+ VH+FE TSV GH+ S+
Sbjct: 8 VLNVAEKPSVAKEASRLLSGGYQNAPTQSRFNPVHQFEFSLQNRSCTMLFTSVRGHLMSL 67
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF YQ+W+ P DL+ A V KN S + ++L AR ++LVLWLDCDREGENI
Sbjct: 68 DFASAYQNWNTIPPEDLYGAPVEKNISQDAGDVRKNLVDLARKAQWLVLWLDCDREGENI 127
Query: 432 CFEVI 446
FEV+
Sbjct: 128 AFEVL 132
Score = 35.8 bits (81), Expect(2) = 6e-24
Identities = 17/38 (44%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T+ D+ +A L P+R+++ AVD R EID
Sbjct: 145 FRAVFSALTKADLERACRTLQAPDRNQSDAVDTRSEID 182
[150][TOP]
>UniRef100_B6KEM8 DNA topoisomerase n=1 Tax=Toxoplasma gondii ME49 RepID=B6KEM8_TOXGO
Length = 677
Score = 99.4 bits (246), Expect(2) = 6e-24
Identities = 56/125 (44%), Positives = 72/125 (57%), Gaps = 2/125 (1%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMF--TRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSV 251
VL VAEKPS+A + +LS G T+ VH+FE TSV GH+ S+
Sbjct: 8 VLNVAEKPSVAKEASRLLSGGYQNAPTQSRFNPVHQFEFSLQNRSCTMLFTSVRGHLMSL 67
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF YQ+W+ P DL+ A V KN S + ++L AR ++LVLWLDCDREGENI
Sbjct: 68 DFASAYQNWNTIPPEDLYGAPVEKNISQDAGDVRKNLVDLARKAQWLVLWLDCDREGENI 127
Query: 432 CFEVI 446
FEV+
Sbjct: 128 AFEVL 132
Score = 35.8 bits (81), Expect(2) = 6e-24
Identities = 17/38 (44%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS++T+ D+ +A L P+R+++ AVD R EID
Sbjct: 145 FRAVFSALTKADLERACRTLQAPDRNQSDAVDTRSEID 182
[151][TOP]
>UniRef100_B4M8K0 DNA topoisomerase n=1 Tax=Drosophila virilis RepID=B4M8K0_DROVI
Length = 1355
Score = 100 bits (248), Expect(2) = 8e-24
Identities = 53/127 (41%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + +V++FE + G A +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTIAGLLSNGSAHRREGYSVYNKVYDFEAQVRGRNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F Y++W DP LF A + K+ I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLEFLVSYRNWRNVDPRSLFDAPIRKSVGENYEPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 34.7 bits (78), Expect(2) = 8e-24
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRASFSEITTTAVRRALLQLGQPDKRQSDAVDVRSELD 178
[152][TOP]
>UniRef100_B4I5W5 DNA topoisomerase n=1 Tax=Drosophila sechellia RepID=B4I5W5_DROSE
Length = 1251
Score = 99.0 bits (245), Expect(2) = 1e-23
Identities = 55/127 (43%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + +V +FE G A +TSV GH+
Sbjct: 2 KYLNVAEKNDAAKTIAGLLSNGAAHRREGYSVYNKVFDFEALVRGKNAKMVMTSVSGHMM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ F Y++W DP LF A V K S I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLAFQVSYKNWRTVDPRSLFDAPVKKGVSADYEPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 35.4 bits (80), Expect(2) = 1e-23
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELD 178
[153][TOP]
>UniRef100_Q9NG98 DNA topoisomerase 3-alpha n=1 Tax=Drosophila melanogaster
RepID=TOP3A_DROME
Length = 1250
Score = 99.0 bits (245), Expect(2) = 1e-23
Identities = 55/129 (42%), Positives = 74/129 (57%), Gaps = 3/129 (2%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGH 239
A K L VAEK A +IA +LS+G R+G + +V +FE G A +TSV GH
Sbjct: 25 AMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGH 84
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ + F Y++W DP LF A V K + I R L +E RGC+ L++W DCDRE
Sbjct: 85 MMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDRE 144
Query: 420 GENICFEVI 446
GENI +E+I
Sbjct: 145 GENIGYEII 153
Score = 35.4 bits (80), Expect(2) = 1e-23
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 166 YRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELD 203
[154][TOP]
>UniRef100_UPI00015B58C3 PREDICTED: similar to topoisomerase III alpha n=1 Tax=Nasonia
vitripennis RepID=UPI00015B58C3
Length = 1078
Score = 96.3 bits (238), Expect(2) = 1e-23
Identities = 51/129 (39%), Positives = 75/129 (58%), Gaps = 4/129 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A +IA LS G ++G + +++EF+ + +TSV GH+
Sbjct: 2 KVLNVAEKNDAAKNIAGYLSRGTSRRKEGLSPYNKIYEFQSRLWNKDCQMIMTSVSGHLL 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKN-ESNPKAHICRHLNQEARGCRFLVLWLDCDREG 422
+ +F G Y+ W PL LF+A V+K + + I + + +E R C L++W DCDREG
Sbjct: 62 NYEFTGAYRKWYGCPPLSLFEAPVVKQCQQDNYEKIKKTIEREVRSCSALIIWTDCDREG 121
Query: 423 ENICFEVIQ 449
ENI FE+IQ
Sbjct: 122 ENIGFEIIQ 130
Score = 38.1 bits (87), Expect(2) = 1e-23
Identities = 19/47 (40%), Positives = 29/47 (61%)
Frame = +1
Query: 451 QLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
Q V + YRA+FS +T+ + +AL +L PN+ + AVD R E+D
Sbjct: 133 QAVKPNIRVYRAKFSEITQISIDRALQSLEEPNKAISDAVDVRSELD 179
[155][TOP]
>UniRef100_UPI000036AB42 PREDICTED: topoisomerase (DNA) III alpha isoform 3 n=1 Tax=Pan
troglodytes RepID=UPI000036AB42
Length = 1001
Score = 97.8 bits (242), Expect(2) = 1e-23
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M R+G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E R C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 1e-23
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[156][TOP]
>UniRef100_Q13472 DNA topoisomerase 3-alpha n=2 Tax=Homo sapiens RepID=TOP3A_HUMAN
Length = 1001
Score = 97.8 bits (242), Expect(2) = 1e-23
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M R+G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E R C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 1e-23
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[157][TOP]
>UniRef100_C9JGM5 Putative uncharacterized protein TOP3A (Fragment) n=1 Tax=Homo
sapiens RepID=C9JGM5_HUMAN
Length = 389
Score = 97.8 bits (242), Expect(2) = 1e-23
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M R+G ++ ++EF+ G +TSV GH+
Sbjct: 15 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 74
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E R C+ LV+W DCDREGE
Sbjct: 75 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 134
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 135 NIGFEII 141
Score = 36.6 bits (83), Expect(2) = 1e-23
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 155 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 191
[158][TOP]
>UniRef100_B4GWY2 DNA topoisomerase n=1 Tax=Drosophila persimilis RepID=B4GWY2_DROPE
Length = 1178
Score = 98.6 bits (244), Expect(2) = 1e-23
Identities = 52/127 (40%), Positives = 75/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + ++++FE G A +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTIAGLLSNGAANRREGYSVYNKIYDFEAPVRGQNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F Y++W DP LF A V K+ I + L +E RGC+ L++W DCDREGE
Sbjct: 62 QLEFQVSYRNWRVVDPGSLFDAPVRKSVGESYLPIKKTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 35.4 bits (80), Expect(2) = 1e-23
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 138 LTIYRASFSEITTIAVRRALQQLGQPDKRQSDAVDVRTELD 178
[159][TOP]
>UniRef100_UPI00005BF14C MGC142307 protein. n=1 Tax=Bos taurus RepID=UPI00005BF14C
Length = 1002
Score = 96.3 bits (238), Expect(2) = 1e-23
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K+L VAEK A IA +LS G+M R+G + +++EF+ G +TSV GH+
Sbjct: 35 KILCVAEKNDAAKGIADLLSGGRMRRREGLSRFNKIYEFDYHLCGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +EA+ C+ LV+W DCDREGE
Sbjct: 95 AHDFRMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLEREAQQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FEVI
Sbjct: 155 NIGFEVI 161
Score = 37.7 bits (86), Expect(2) = 1e-23
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T + V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITTRAVRTACENLTEPDQRVSDAVDVRQELD 211
[160][TOP]
>UniRef100_A0JN73 DNA topoisomerase n=1 Tax=Bos taurus RepID=A0JN73_BOVIN
Length = 1002
Score = 96.3 bits (238), Expect(2) = 1e-23
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K+L VAEK A IA +LS G+M R+G + +++EF+ G +TSV GH+
Sbjct: 35 KILCVAEKNDAAKGIADLLSGGRMRRREGLSRFNKIYEFDYHLCGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +EA+ C+ LV+W DCDREGE
Sbjct: 95 AHDFRMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLEREAQQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FEVI
Sbjct: 155 NIGFEVI 161
Score = 37.7 bits (86), Expect(2) = 1e-23
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T + V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITTRAVRTACENLTEPDQRVSDAVDVRQELD 211
[161][TOP]
>UniRef100_Q4SVN5 DNA topoisomerase (Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4SVN5_TETNG
Length = 984
Score = 99.4 bits (246), Expect(2) = 1e-23
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A I+ ++S+G+ R+G ++ ++EFE LG +TSV GH+
Sbjct: 10 RVLCVAEKNDAAKGISEIMSNGRFRRREGMSKFNKIYEFEYHLLGQNVTVAMTSVSGHLL 69
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+++F +Q W + +P+ LF A+V K + I R L +E + C+ LV+W DCDREGE
Sbjct: 70 ALEFKAPFQKWHSCNPVILFDAEVEKYCPDNMVQIKRTLEKEVKQCQLLVIWTDCDREGE 129
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 130 NIGFEII 136
Score = 34.7 bits (78), Expect(2) = 1e-23
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T + +A L P+ + + AVD RQE+D
Sbjct: 150 RAKFSEITPNSIRRACSTLTEPDSNVSDAVDVRQELD 186
[162][TOP]
>UniRef100_UPI00017B4843 UPI00017B4843 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4843
Length = 953
Score = 99.4 bits (246), Expect(2) = 1e-23
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A I+ ++S+G+ R+G ++ ++EFE LG +TSV GH+
Sbjct: 3 RVLCVAEKNDAAKGISEIMSNGRFRRREGMSKFNKIYEFEYHLLGQNVTVAMTSVSGHLL 62
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+++F +Q W + +P+ LF A+V K + I R L +E + C+ LV+W DCDREGE
Sbjct: 63 ALEFKAPFQKWHSCNPVILFDAEVEKYCPDNMVQIKRTLEKEVKQCQLLVIWTDCDREGE 122
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 123 NIGFEII 129
Score = 34.7 bits (78), Expect(2) = 1e-23
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T + +A L P+ + + AVD RQE+D
Sbjct: 143 RAKFSEITPNSIRRACSTLTEPDSNVSDAVDVRQELD 179
[163][TOP]
>UniRef100_A2FIZ8 DNA topoisomerase n=1 Tax=Trichomonas vaginalis G3
RepID=A2FIZ8_TRIVA
Length = 644
Score = 95.1 bits (235), Expect(2) = 2e-23
Identities = 50/129 (38%), Positives = 73/129 (56%), Gaps = 3/129 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE---FEGKFLGSPAHFKVTSVIG 236
M ++L VAEKPS+A A++LS+G M T+KG ++ + F F G A TSV G
Sbjct: 1 MPKQILCVAEKPSVAREAANILSNGHMETKKGKSKYNNNFVFHRNFQGEDAKVIFTSVAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
HV + DFP +Y++W LF +++ ++ + +L Q+AR + LWLD DR
Sbjct: 61 HVLNYDFPPEYKNWETFGNTKLFDCRIISGVTSNMQDVVDNLQQQARSVNLVFLWLDNDR 120
Query: 417 EGENICFEV 443
EGE I EV
Sbjct: 121 EGEGISEEV 129
Score = 38.5 bits (88), Expect(2) = 2e-23
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +1
Query: 475 FYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
F RARFS ++ ++++ A +N NR++A AV RQEID
Sbjct: 142 FKRARFSGLSPREIIHAFNNPTPINRNDAAAVKLRQEID 180
[164][TOP]
>UniRef100_UPI0000D9E1BC PREDICTED: similar to topoisomerase (DNA) III alpha n=1 Tax=Macaca
mulatta RepID=UPI0000D9E1BC
Length = 1001
Score = 96.7 bits (239), Expect(2) = 2e-23
Identities = 53/127 (41%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS G+M R+G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSSGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E R C+ LV+W DCDREGE
Sbjct: 95 AHDFRMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 2e-23
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[165][TOP]
>UniRef100_Q6GPC0 DNA topoisomerase n=1 Tax=Xenopus laevis RepID=Q6GPC0_XENLA
Length = 1022
Score = 95.9 bits (237), Expect(2) = 3e-23
Identities = 50/127 (39%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA ++S+ +M R+G ++ ++E+E G +TSV GH+
Sbjct: 40 KVLCVAEKNDAAKGIADLMSNSRMRRREGFSKFNKIYEYEYHLFGKDVTVVMTSVSGHLL 99
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+++F + W + +P+ LF+A+V K + +I R L +E R C+ L++W DCDREGE
Sbjct: 100 ALEFMDHMKKWHSCNPVSLFEAEVQKYCPDDFVNIKRTLEREVRQCQALIIWTDCDREGE 159
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 160 NIGFEII 166
Score = 37.0 bits (84), Expect(2) = 3e-23
Identities = 16/41 (39%), Positives = 28/41 (68%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T + + A ++LV+P+++ AVD R E+D
Sbjct: 176 LQVFRARFSEITPRSIRMACEHLVQPDQNINDAVDVRTELD 216
[166][TOP]
>UniRef100_UPI00005A0C5A PREDICTED: similar to topoisomerase (DNA) III alpha n=1 Tax=Canis
lupus familiaris RepID=UPI00005A0C5A
Length = 989
Score = 95.5 bits (236), Expect(2) = 3e-23
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
K+L VAEK A IA +LS+G+M R+G ++ ++EF+ G +TSV GH+
Sbjct: 35 KILCVAEKNDAAKGIADLLSNGRMRRREGFSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E + C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVGIKKTLQRETQQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 37.4 bits (85), Expect(2) = 3e-23
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T + V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPRAVRVACENLTEPDQRVSDAVDVRQELD 211
[167][TOP]
>UniRef100_UPI000175F461 PREDICTED: topoisomerase (DNA) III alpha n=1 Tax=Danio rerio
RepID=UPI000175F461
Length = 977
Score = 95.9 bits (237), Expect(2) = 3e-23
Identities = 51/127 (40%), Positives = 75/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA ++S+G+ R+G + +++E+E G +TSV GH+
Sbjct: 9 KVLCVAEKNDAAKGIAEIMSNGRSRRREGCSVYNKIYEYEYNLFGQNVTVNMTSVSGHLL 68
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+++F +Q W + P+ LF A+V K I R L +E R C+ L++W DCDREGE
Sbjct: 69 ALEFKAPFQKWHSCSPVLLFDAEVEKYCPENFIPIKRTLEREVRQCQALIVWTDCDREGE 128
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 129 NIGFEII 135
Score = 37.0 bits (84), Expect(2) = 3e-23
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS +T + +A + L P+ + + AVD RQE+D
Sbjct: 148 FRARFSEITPNSIRRACETLTEPDINVSDAVDVRQELD 185
[168][TOP]
>UniRef100_A0DEK9 Chromosome undetermined scaffold_48, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DEK9_PARTE
Length = 859
Score = 95.5 bits (236), Expect(2) = 3e-23
Identities = 54/128 (42%), Positives = 77/128 (60%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLS--HGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
KVL VAEKPS+A SIA+VLS H T+ ++ + + + +TSV GH+ S
Sbjct: 14 KVLNVAEKPSVARSIANVLSKDHRIEETKSPFNKLFKLDYRLKDVEVEMWITSVTGHLKS 73
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +P KYQ W DP+ + +A++ N S K ++ +L A C L+LWLDCDREGE
Sbjct: 74 LKYPQKYQSWEKWDPIIILKEAEIENNISTDKQNLELNLKNFASICNRLILWLDCDREGE 133
Query: 426 NICFEVIQ 449
NI FEV++
Sbjct: 134 NIAFEVME 141
Score = 37.4 bits (85), Expect(2) = 3e-23
Identities = 20/37 (54%), Positives = 27/37 (72%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS+VT DV +ALD L P+++ + +V ARQEID
Sbjct: 154 RAHFSAVTYVDVRRALDTLKYPDQNLSNSVIARQEID 190
[169][TOP]
>UniRef100_B4Q9Z3 DNA topoisomerase n=1 Tax=Drosophila simulans RepID=B4Q9Z3_DROSI
Length = 857
Score = 97.4 bits (241), Expect(2) = 3e-23
Identities = 54/127 (42%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + +V +FE G A +TSV GH+
Sbjct: 2 KYLNVAEKNDAAKTIAGLLSNGAAHRREGYSVYNKVFDFEALVRGKNAKMVMTSVSGHMM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ F Y++W DP LF A V K I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLAFQVSYKNWRTVDPRSLFDAPVKKGVGADYEPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 35.4 bits (80), Expect(2) = 3e-23
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELD 178
[170][TOP]
>UniRef100_Q171C3 DNA topoisomerase n=1 Tax=Aedes aegypti RepID=Q171C3_AEDAE
Length = 1021
Score = 97.8 bits (242), Expect(2) = 4e-23
Identities = 52/128 (40%), Positives = 75/128 (58%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS G R+G + +++EF G P +TSV GH+
Sbjct: 26 KYLNVAEKNDAAKNIAGLLSRGSSQRREGYSPYNKIYEFSYNIRGQPVQMVMTSVSGHLL 85
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +F ++ W + +P LF A V K+ + I + L +E RGC+ LV+W DCDREGE
Sbjct: 86 NYEFLPSFRGWHSCNPEQLFDAPVRKSCTENMGKIKQTLEREVRGCQTLVIWTDCDREGE 145
Query: 426 NICFEVIQ 449
NI FE+I+
Sbjct: 146 NIGFEIIE 153
Score = 34.7 bits (78), Expect(2) = 4e-23
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T V +A++NL P+ ++ AV+ R E+D
Sbjct: 166 RAKFSEITAASVKRAVENLAAPDELQSEAVNVRSELD 202
[171][TOP]
>UniRef100_A0DS57 Chromosome undetermined scaffold_61, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DS57_PARTE
Length = 895
Score = 92.4 bits (228), Expect(2) = 4e-23
Identities = 52/128 (40%), Positives = 77/128 (60%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMF--TRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
+VL VAEKPS+A SIA+VL+ T+ ++ +F K A +TSV GH+ +
Sbjct: 14 RVLNVAEKPSVARSIATVLARDHTIEETKSPYNKLFKFNFKLGEQDAEMWMTSVTGHLKN 73
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNE-SNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +P +YQ W DPL + + ++N S K + +L + A+ C L+LWLDCDREGE
Sbjct: 74 LKYPKQYQKWDKWDPLIILKDAEIENVISYEKRFLEENLQRFAKQCSQLILWLDCDREGE 133
Query: 426 NICFEVIQ 449
NI FEV++
Sbjct: 134 NIAFEVLE 141
Score = 40.0 bits (92), Expect(2) = 4e-23
Identities = 20/38 (52%), Positives = 29/38 (76%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS+VT D+ KAL+NL +P+ + + +V ARQEID
Sbjct: 153 HRAHFSAVTYVDIKKALENLQQPDENLSNSVLARQEID 190
[172][TOP]
>UniRef100_B3MN55 DNA topoisomerase n=1 Tax=Drosophila ananassae RepID=B3MN55_DROAN
Length = 1209
Score = 95.9 bits (237), Expect(2) = 5e-23
Identities = 52/127 (40%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +I+ +LS+G R+G + +V++FE GS + +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTISGLLSNGTARRREGYSVYNKVYDFEAVVRGSNSKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F +++W DP LF A V K+ I R L +E RGC+ L++W DCDREGE
Sbjct: 62 QLEFLVSFRNWRNVDPGSLFDAPVRKSVGKDYEPIKRTLEREVRGCQGLIIWTDCDREGE 121
Query: 426 NICFEVI 446
NI +E+I
Sbjct: 122 NIGYEII 128
Score = 36.2 bits (82), Expect(2) = 5e-23
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS +T V +AL L +P++ ++ AVD R E+D
Sbjct: 141 YRANFSEITTVAVRRALQQLGQPDKRQSDAVDVRSELD 178
[173][TOP]
>UniRef100_UPI0000DB782E PREDICTED: similar to topoisomerase (DNA) III alpha n=1 Tax=Apis
mellifera RepID=UPI0000DB782E
Length = 958
Score = 93.6 bits (231), Expect(2) = 5e-23
Identities = 53/128 (41%), Positives = 72/128 (56%), Gaps = 4/128 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VL VAEK A +IA+ LS G R+G ++ EF H +TSV GH+ +
Sbjct: 3 VLNVAEKNDAAKNIAAYLSRGTYKRREGLWLYNKIFEFNSYLWNKNCHMIMTSVSGHLLN 62
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKA-HICRHLNQEARGCRFLVLWLDCDREGE 425
+F G Y+ W + PL LF A V+K S + I + L +E + C L++W DCDREGE
Sbjct: 63 CEFVGIYRKWQSCHPLSLFDAPVVKQCSQESSIKIKKTLEKEVQKCNALIIWTDCDREGE 122
Query: 426 NICFEVIQ 449
NI FE+IQ
Sbjct: 123 NIGFEIIQ 130
Score = 38.5 bits (88), Expect(2) = 5e-23
Identities = 17/38 (44%), Positives = 26/38 (68%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FS +T+ V ++L NL P++ + AVD R E+D
Sbjct: 142 YRAKFSEITQTSVNRSLQNLCEPDKAISDAVDVRSELD 179
[174][TOP]
>UniRef100_UPI0001796D24 PREDICTED: similar to topoisomerase (DNA) III alpha n=1 Tax=Equus
caballus RepID=UPI0001796D24
Length = 1152
Score = 94.0 bits (232), Expect(2) = 6e-23
Identities = 51/127 (40%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
K+L VAEK A IA +LS G+ R+G ++ ++EF+ G +TSV GH+
Sbjct: 180 KILCVAEKNDAAKEIADLLSDGRARRREGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 239
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E R C+ LV+W DCDREGE
Sbjct: 240 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 299
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 300 NIGFEII 306
Score = 37.7 bits (86), Expect(2) = 6e-23
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T + V A +NL P++ + AVD RQE+D
Sbjct: 320 RARFSEITPRAVRTACENLTEPDQRVSDAVDVRQELD 356
[175][TOP]
>UniRef100_UPI0000ECABF1 topoisomerase (DNA) III alpha n=1 Tax=Gallus gallus
RepID=UPI0000ECABF1
Length = 1020
Score = 93.6 bits (231), Expect(2) = 6e-23
Identities = 51/127 (40%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+ +M R+G ++ ++E++ + G +TSV GH+
Sbjct: 37 KVLCVAEKNDAARGIADLLSNSRMRRREGFSKFNKIYEYDYQMFGQNVTMVMTSVSGHLL 96
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF ++ W + +PL LF A++ K I R L +E + C+ LV+W DCDREGE
Sbjct: 97 AHDFKLPFRKWHSCNPLALFDAEIEKYCPENYVDIKRTLEREVQQCQALVIWTDCDREGE 156
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 157 NIGFEII 163
Score = 38.1 bits (87), Expect(2) = 6e-23
Identities = 17/41 (41%), Positives = 28/41 (68%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T V +A +NL +P++ + AV+ RQE+D
Sbjct: 173 LQVFRARFSEITLHAVRRACENLTQPDQKTSDAVEVRQELD 213
[176][TOP]
>UniRef100_Q4W5X0 DNA topoisomerase n=1 Tax=Gallus gallus RepID=Q4W5X0_CHICK
Length = 1020
Score = 93.6 bits (231), Expect(2) = 6e-23
Identities = 51/127 (40%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+ +M R+G ++ ++E++ + G +TSV GH+
Sbjct: 37 KVLCVAEKNDAARGIADLLSNSRMRRREGFSKFNKIYEYDYQMFGQNVTMVMTSVSGHLL 96
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF ++ W + +PL LF A++ K I R L +E + C+ LV+W DCDREGE
Sbjct: 97 AHDFKLPFRKWHSCNPLALFDAEIEKYCPENYVDIKRTLEREVQQCQALVIWTDCDREGE 156
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 157 NIGFEII 163
Score = 38.1 bits (87), Expect(2) = 6e-23
Identities = 17/41 (41%), Positives = 28/41 (68%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T V +A +NL +P++ + AV+ RQE+D
Sbjct: 173 LQVFRARFSEITLHAVRRACENLTQPDQKTSDAVEVRQELD 213
[177][TOP]
>UniRef100_A4URT1 DNA topoisomerase n=3 Tax=Trypanosoma brucei RepID=A4URT1_TRYBB
Length = 918
Score = 88.6 bits (218), Expect(2) = 8e-23
Identities = 55/140 (39%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
Frame = +3
Query: 81 LMVAEKPSIALSIASVLSHGQMFT-RKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDF 257
L VAEKPS+A IA++LS G T R S FE F G TSV GH+ DF
Sbjct: 5 LNVAEKPSVAREIATILSGGNQRTIRSHSIYNPVFEFNFEGKT--MICTSVSGHLMESDF 62
Query: 258 PGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICF 437
P + W++ +DLF +K + + I ++L + R L LW+DCDREGENICF
Sbjct: 63 PPQAAGWASFPIIDLFTLGTVKRVRSDLSEIQKNLRELGRRATTLALWMDCDREGENICF 122
Query: 438 EVIQSTGFNVNDVLSCTVFF 497
EVI + + C F
Sbjct: 123 EVIDVVQKEHSSISICRAHF 142
Score = 42.7 bits (99), Expect(2) = 8e-23
Identities = 20/37 (54%), Positives = 29/37 (78%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++T++D+L A+ NL PNR + AV+ARQE+D
Sbjct: 139 RAHFSALTKRDILGAMRNLKAPNRALSEAVEARQELD 175
[178][TOP]
>UniRef100_B4KIW5 DNA topoisomerase n=1 Tax=Drosophila mojavensis RepID=B4KIW5_DROMO
Length = 1279
Score = 97.8 bits (242), Expect(2) = 1e-22
Identities = 53/128 (41%), Positives = 75/128 (58%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS+G R+G + +V++FE G A +TSV GH+
Sbjct: 2 KFLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVYDFEAPVRGRNAKMVMTSVSGHLM 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F Y++W DP LF A + K S I R L +E R C+ L++W DCDREGE
Sbjct: 62 ELEFLQSYRNWRNVDPRSLFDAPIRKTVSENFLPIKRTLEREVRSCQGLIIWTDCDREGE 121
Query: 426 NICFEVIQ 449
NI +E+I+
Sbjct: 122 NIGYEIIE 129
Score = 33.1 bits (74), Expect(2) = 1e-22
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS +T V +AL L P++ ++ AVD R E+D
Sbjct: 141 HRATFSEITSVAVRRALQQLGLPDKRQSDAVDVRSELD 178
[179][TOP]
>UniRef100_UPI0001B7A289 UPI0001B7A289 related cluster n=1 Tax=Rattus norvegicus
RepID=UPI0001B7A289
Length = 949
Score = 95.9 bits (237), Expect(2) = 1e-22
Identities = 52/127 (40%), Positives = 79/127 (62%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ WS+ +PL LF+A++ K I + L +E + C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWSSCNPLVLFEAEIEKYCPENFIDIKKTLERETQHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 35.0 bits (79), Expect(2) = 1e-22
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A ++L P++ + AVD RQE+D
Sbjct: 175 RARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELD 211
[180][TOP]
>UniRef100_Q7Q111 DNA topoisomerase n=1 Tax=Anopheles gambiae RepID=Q7Q111_ANOGA
Length = 1025
Score = 93.6 bits (231), Expect(2) = 1e-22
Identities = 51/128 (39%), Positives = 72/128 (56%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA +LS G R+G + +++EF G +TSV GH+
Sbjct: 30 KYLNVAEKNDAAKTIAGLLSRGSSQRREGYSPYNKIYEFSYNLHGQSIQMIMTSVSGHLL 89
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +F ++ W + P DLF A V KN I + L +E RGC L++W DCDREGE
Sbjct: 90 THEFLPSFRGWHSCSPEDLFDAPVRKNCPEQYEKIKKTLEREVRGCSALIIWTDCDREGE 149
Query: 426 NICFEVIQ 449
NI +E+I+
Sbjct: 150 NIGYEIIE 157
Score = 37.0 bits (84), Expect(2) = 1e-22
Identities = 15/38 (39%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA+FS +T + +A++NLV+P+ + AV+ R E+D
Sbjct: 169 FRAKFSEITAPSIKRAIENLVQPDARQNDAVNVRSELD 206
[181][TOP]
>UniRef100_O70157 DNA topoisomerase 3-alpha n=2 Tax=Mus musculus RepID=TOP3A_MOUSE
Length = 1003
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[182][TOP]
>UniRef100_B0WGC0 DNA topoisomerase n=1 Tax=Culex quinquefasciatus RepID=B0WGC0_CULQU
Length = 992
Score = 94.7 bits (234), Expect(2) = 1e-22
Identities = 52/128 (40%), Positives = 74/128 (57%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
K L VAEK A +IA++LS G R+G + +++EF+ G +TSV GH+
Sbjct: 2 KYLNVAEKNDAAKNIAALLSRGASQRREGYSPYNKIYEFDYNLRGQQVKMVMTSVSGHLL 61
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ +F ++ W + +P LF A V K + I R L +E RGC LV+W DCDREGE
Sbjct: 62 NFEFLPSFRGWHSCNPEQLFDAPVRKGCTESAEKIKRTLEREIRGCGALVIWTDCDREGE 121
Query: 426 NICFEVIQ 449
NI FE+I+
Sbjct: 122 NIGFEIIE 129
Score = 35.8 bits (81), Expect(2) = 1e-22
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T + +A+DNL P+ ++ AV+ R E+D
Sbjct: 142 RAKFSEITAASIKRAVDNLAAPDELQSEAVNVRSELD 178
[183][TOP]
>UniRef100_Q3V3P1 DNA topoisomerase n=1 Tax=Mus musculus RepID=Q3V3P1_MOUSE
Length = 954
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[184][TOP]
>UniRef100_Q5NCT0 DNA topoisomerase n=1 Tax=Mus musculus RepID=Q5NCT0_MOUSE
Length = 773
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 10 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 69
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 70 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 129
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 130 NIGFEII 136
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 150 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 186
[185][TOP]
>UniRef100_Q3TBE3 DNA topoisomerase n=1 Tax=Mus musculus RepID=Q3TBE3_MOUSE
Length = 773
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 10 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 69
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 70 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 129
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 130 NIGFEII 136
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 150 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 186
[186][TOP]
>UniRef100_Q3TPE4 DNA topoisomerase n=1 Tax=Mus musculus RepID=Q3TPE4_MOUSE
Length = 694
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 175 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 211
[187][TOP]
>UniRef100_B0QZI1 DNA topoisomerase n=1 Tax=Mus musculus RepID=B0QZI1_MOUSE
Length = 670
Score = 94.0 bits (232), Expect(2) = 1e-22
Identities = 51/127 (40%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 10 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 69
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E C+ LV+W DCDREGE
Sbjct: 70 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGE 129
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 130 NIGFEII 136
Score = 36.6 bits (83), Expect(2) = 1e-22
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A +NL P++ + AVD RQE+D
Sbjct: 150 RARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELD 186
[188][TOP]
>UniRef100_UPI000194D5CF PREDICTED: topoisomerase (DNA) III alpha n=1 Tax=Taeniopygia
guttata RepID=UPI000194D5CF
Length = 1009
Score = 92.0 bits (227), Expect(2) = 3e-22
Identities = 51/127 (40%), Positives = 75/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+ +M R+G ++ ++E++ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAARGIAELLSNSRMRRREGFSKFNKIYEYDYHMFGQNVTMVMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF ++ W + +PL LF A++ K I R L +E + C+ LV+W DCDREGE
Sbjct: 95 AHDFVMPFRKWHSCNPLALFDAEIEKYCPENYLDIKRTLEREIQQCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 37.4 bits (85), Expect(2) = 3e-22
Identities = 17/41 (41%), Positives = 27/41 (65%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T V A ++L +P++ + AVD RQE+D
Sbjct: 171 LQVFRARFSEITPHAVRAACEHLTQPDQKTSDAVDVRQELD 211
[189][TOP]
>UniRef100_UPI0001B7A288 topoisomerase (DNA) III alpha n=1 Tax=Rattus norvegicus
RepID=UPI0001B7A288
Length = 1001
Score = 94.4 bits (233), Expect(2) = 3e-22
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E + C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETQHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 35.0 bits (79), Expect(2) = 3e-22
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A ++L P++ + AVD RQE+D
Sbjct: 175 RARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELD 211
[190][TOP]
>UniRef100_UPI0000DA3574 PREDICTED: similar to topoisomerase (DNA) III alpha n=1 Tax=Rattus
norvegicus RepID=UPI0000DA3574
Length = 735
Score = 94.4 bits (233), Expect(2) = 3e-22
Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
KVL VAEK A IA +LS+G+M ++G ++ ++EF+ G +TSV GH+
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLL 94
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I + L +E + C+ LV+W DCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETQHCQALVIWTDCDREGE 154
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 155 NIGFEII 161
Score = 35.0 bits (79), Expect(2) = 3e-22
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V A ++L P++ + AVD RQE+D
Sbjct: 175 RARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELD 211
[191][TOP]
>UniRef100_UPI00016E29E0 UPI00016E29E0 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E29E0
Length = 966
Score = 93.6 bits (231), Expect(2) = 4e-22
Identities = 48/127 (37%), Positives = 74/127 (58%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A I+ ++S+G+ R+G ++ ++E+E G +TSV GH+
Sbjct: 6 RVLCVAEKNDAAKGISDIMSNGRFRRREGMSKFNKIYEYEYHLFGQNVTVLMTSVSGHLL 65
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F +Q W + P+ LF A+V K I R L +E + C+ L++W DCDREGE
Sbjct: 66 GLEFKTPFQKWHSCSPVLLFDAEVEKYCPENMVQIKRTLEKEVKQCQLLIIWTDCDREGE 125
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 126 NIGFEII 132
Score = 35.4 bits (80), Expect(2) = 4e-22
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T + +A D L P+ + AVD RQE+D
Sbjct: 146 RAKFSEITPNSIRRACDTLSEPDSKVSDAVDVRQELD 182
[192][TOP]
>UniRef100_UPI00016E29DF UPI00016E29DF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E29DF
Length = 964
Score = 93.6 bits (231), Expect(2) = 4e-22
Identities = 48/127 (37%), Positives = 74/127 (58%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+VL VAEK A I+ ++S+G+ R+G ++ ++E+E G +TSV GH+
Sbjct: 10 RVLCVAEKNDAAKGISDIMSNGRFRRREGMSKFNKIYEYEYHLFGQNVTVLMTSVSGHLL 69
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
++F +Q W + P+ LF A+V K I R L +E + C+ L++W DCDREGE
Sbjct: 70 GLEFKTPFQKWHSCSPVLLFDAEVEKYCPENMVQIKRTLEKEVKQCQLLIIWTDCDREGE 129
Query: 426 NICFEVI 446
NI FE+I
Sbjct: 130 NIGFEII 136
Score = 35.4 bits (80), Expect(2) = 4e-22
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS +T + +A D L P+ + AVD RQE+D
Sbjct: 150 RAKFSEITPNSIRRACDTLSEPDSKVSDAVDVRQELD 186
[193][TOP]
>UniRef100_UPI000186EA7F DNA topoisomerase 3-alpha, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186EA7F
Length = 901
Score = 86.3 bits (212), Expect(2) = 5e-22
Identities = 48/126 (38%), Positives = 68/126 (53%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVFS 248
+L VAEK A +I+ LS G R+ + +++EFE K +TSV GH+ +
Sbjct: 3 ILNVAEKNDAAKNISFFLSKGSARKRESLSVYNKIYEFEFKLFNQNCKMVMTSVSGHLLN 62
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
FP +++WS TDP LF V K + +L E + C L++W DCDREGEN
Sbjct: 63 YCFPPTHKNWSTTDPSSLFTVPVNKFCAKENFKTQNNLKNEVKYCDTLIIWTDCDREGEN 122
Query: 429 ICFEVI 446
I FE+I
Sbjct: 123 IGFEII 128
Score = 42.4 bits (98), Expect(2) = 5e-22
Identities = 18/38 (47%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA+FS +T V++A++NL PN+ + AVD R E+D
Sbjct: 141 YRAKFSEITSASVMRAINNLEMPNKSLSDAVDVRMELD 178
[194][TOP]
>UniRef100_A5BX18 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BX18_VITVI
Length = 632
Score = 107 bits (268), Expect = 5e-22
Identities = 65/137 (47%), Positives = 73/137 (53%), Gaps = 4/137 (2%)
Frame = +3
Query: 66 MAP----KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVI 233
MAP K+LMVAEKPS ALSIAS LS G M TR+ S VHEF G F GS A +KVTSVI
Sbjct: 411 MAPPKPHKILMVAEKPSSALSIASALSDGHMSTRRSSIXVHEFNGTFXGSNAQYKVTSVI 470
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
G L+ EAR C LVLW DCD
Sbjct: 471 G---------------------------------------MRLSXEARDCGHLVLWXDCD 491
Query: 414 REGENICFEVIQSTGFN 464
REG+NICFEV++ TGF+
Sbjct: 492 REGDNICFEVVECTGFH 508
[195][TOP]
>UniRef100_C1LZJ7 Prokaryotic DNA topoisomerase, putative n=1 Tax=Schistosoma mansoni
RepID=C1LZJ7_SCHMA
Length = 1165
Score = 90.5 bits (223), Expect(2) = 7e-22
Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
K+L VAEK A +I+ +LS G R+G ++ ++EF G +TSV GH+
Sbjct: 27 KILNVAEKNDAAKNISEILSRGGYHRREGISKFNKIYEFPMNLNGQNVMMVMTSVSGHLT 86
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF Y+ W + +P+ LF A ++K I + L +E R C+ L++W DCDREGE
Sbjct: 87 NYDFLPNYKSWHSCNPMVLFDAPIVKQVLKDYEPIKQTLQREVRSCQKLIIWTDCDREGE 146
Query: 426 NICFEVI 446
NI EVI
Sbjct: 147 NIGVEVI 153
Score = 37.7 bits (86), Expect(2) = 7e-22
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS +T V +A+D L P+ + + AVD RQE+D
Sbjct: 167 RARFSEITPAAVHRAVDRLTIPDYNASTAVDVRQELD 203
[196][TOP]
>UniRef100_A9CRV1 DNA topoisomerase III n=1 Tax=Enterocytozoon bieneusi H348
RepID=A9CRV1_ENTBH
Length = 722
Score = 82.8 bits (203), Expect(2) = 2e-21
Identities = 45/129 (34%), Positives = 77/129 (59%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDF 257
++ VAEKPS+A SIA++ S+ + KG + + KF+ + TSV+GH++ +F
Sbjct: 3 IVNVAEKPSVAKSIANIFSNS-VEVYKGQNK-YCLNHKFIFKNNNMIFTSVLGHMYEFEF 60
Query: 258 PGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICF 437
P +Y++W+ +P +LF A++ K +I +++ + +V+W DCDREGENI
Sbjct: 61 PSEYKNWNTINPKNLFTAKIYKKLKTESIYIKKNIEDLSINADLVVIWTDCDREGENI-G 119
Query: 438 EVIQSTGFN 464
+ IQS +N
Sbjct: 120 KQIQSLVYN 128
Score = 43.9 bits (102), Expect(2) = 2e-21
Identities = 21/37 (56%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS++++ ++LKA DNL N+ E+ AV+ARQEID
Sbjct: 133 RARFSAISKHEILKAFDNLCDINQYESDAVEARQEID 169
[197][TOP]
>UniRef100_Q5I6D5 DNA topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q5I6D5_TRYCR
Length = 921
Score = 83.6 bits (205), Expect(2) = 1e-20
Identities = 50/131 (38%), Positives = 70/131 (53%), Gaps = 5/131 (3%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHG-----QMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIG 236
P L VAEKPS+A ++ VLS+G +R +FEGK TSV G
Sbjct: 2 PTWLNVAEKPSVAKELSLVLSNGTCRMGNSLSRFNPVFEFDFEGK------QMLCTSVAG 55
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ + +FP + + W ++LF A + K+ + ++L R LVLW+DCDR
Sbjct: 56 HLMNDEFPPETRSWQNYPLVNLFTASITKHVKPEMEPVKKNLEALGRRSSNLVLWMDCDR 115
Query: 417 EGENICFEVIQ 449
EGENICFEV+Q
Sbjct: 116 EGENICFEVMQ 126
Score = 40.8 bits (94), Expect(2) = 1e-20
Identities = 21/47 (44%), Positives = 33/47 (70%)
Frame = +1
Query: 451 QLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
Q V+ + +RA FS++T +D+L A+ +L PN+ + AV+ARQEID
Sbjct: 129 QGVNRSISIFRAHFSALTRRDLLSAVRSLKAPNKALSDAVEARQEID 175
[198][TOP]
>UniRef100_Q4DJB7 DNA topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q4DJB7_TRYCR
Length = 921
Score = 83.6 bits (205), Expect(2) = 1e-20
Identities = 50/131 (38%), Positives = 70/131 (53%), Gaps = 5/131 (3%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHG-----QMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIG 236
P L VAEKPS+A ++ VLS+G +R +FEGK TSV G
Sbjct: 2 PTWLNVAEKPSVAKELSLVLSNGTCRMGNSLSRFNPVFEFDFEGK------QMLCTSVAG 55
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ + +FP + + W ++LF A + K+ + ++L R LVLW+DCDR
Sbjct: 56 HLMNDEFPPETRSWQNYPLVNLFTASITKHVKPEMEPVKKNLEALGRRSSNLVLWMDCDR 115
Query: 417 EGENICFEVIQ 449
EGENICFEV+Q
Sbjct: 116 EGENICFEVMQ 126
Score = 40.8 bits (94), Expect(2) = 1e-20
Identities = 21/47 (44%), Positives = 33/47 (70%)
Frame = +1
Query: 451 QLVSM*MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
Q V+ + +RA FS++T +D+L A+ +L PN+ + AV+ARQEID
Sbjct: 129 QGVNRSISIFRAHFSALTRRDLLSAVRSLKAPNKALSDAVEARQEID 175
[199][TOP]
>UniRef100_UPI0001A2D768 UPI0001A2D768 related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2D768
Length = 1003
Score = 87.0 bits (214), Expect(2) = 1e-20
Identities = 54/145 (37%), Positives = 78/145 (53%), Gaps = 3/145 (2%)
Frame = +3
Query: 21 NRFIGEAETS*IETKMAPKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGK 191
+RF S I KVL VAEK A IA ++S+G+ R+G + +++E+E
Sbjct: 17 SRFYRHISVSMIRRTQIKKVLCVAEKNDAAKGIAEIMSNGRSRRREGCSVYNKIYEYEYN 76
Query: 192 FLGSPAHFKVTSVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQE 371
G +TSV GH+ +++F K + P+ LF A+V K I R L +E
Sbjct: 77 LFGQNVTVNMTSVSGHLLALEF--KVLHRHSCSPVLLFDAEVEKYCPENFIPIKRTLERE 134
Query: 372 ARGCRFLVLWLDCDREGENICFEVI 446
R C+ L++W DCDREGENI FE+I
Sbjct: 135 VRQCQALIVWTDCDREGENIGFEII 159
Score = 37.0 bits (84), Expect(2) = 1e-20
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS +T + +A + L P+ + + AVD RQE+D
Sbjct: 172 FRARFSEITPNSIRRACETLTEPDINVSDAVDVRQELD 209
[200][TOP]
>UniRef100_Q4DNR5 DNA topoisomerase n=1 Tax=Trypanosoma cruzi RepID=Q4DNR5_TRYCR
Length = 921
Score = 84.0 bits (206), Expect(2) = 2e-20
Identities = 50/131 (38%), Positives = 70/131 (53%), Gaps = 5/131 (3%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHG-----QMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIG 236
P L VAEKPS+A ++ VLS+G +R +FEGK TSV G
Sbjct: 2 PTWLNVAEKPSVAKELSLVLSNGTCKMGNSLSRFNPVFEFDFEGK------QMLCTSVAG 55
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ + +FP + + W ++LF A + K+ + ++L R LVLW+DCDR
Sbjct: 56 HLMNDEFPPETRSWQNYPLVNLFTASITKHVKPEMEPVKKNLEALGRRASNLVLWMDCDR 115
Query: 417 EGENICFEVIQ 449
EGENICFEV+Q
Sbjct: 116 EGENICFEVMQ 126
Score = 39.3 bits (90), Expect(2) = 2e-20
Identities = 19/37 (51%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++T +D+L A+ +L PN+ + AV+ARQEID
Sbjct: 139 RAHFSALTRRDLLSAVRSLKAPNKALSDAVEARQEID 175
[201][TOP]
>UniRef100_A4HPI6 DNA topoisomerase n=1 Tax=Leishmania braziliensis
RepID=A4HPI6_LEIBR
Length = 951
Score = 84.0 bits (206), Expect(2) = 6e-20
Identities = 52/127 (40%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE-FEGKFLGSPAHFKVTSVIGHVFS 248
P L VAEKPS+A +A LS G T + + + FE F G VTSV+GH+
Sbjct: 2 PTWLNVAEKPSVAKEMAQSLSGGHCRTVQSQSRFNPVFEFNFEGKT--MLVTSVVGHLME 59
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
FP ++WS LF A + K + ++L A L+LWLDCDREGEN
Sbjct: 60 DQFPPNTKNWSTYPFQGLFSAPISKYVRTDLEPVKKNLEALATRADALILWLDCDREGEN 119
Query: 429 ICFEVIQ 449
ICFEV+Q
Sbjct: 120 ICFEVMQ 126
Score = 37.7 bits (86), Expect(2) = 6e-20
Identities = 18/37 (48%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++T +D+L A+ NL P++ + AV+ARQE+D
Sbjct: 139 RAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMD 175
[202][TOP]
>UniRef100_B7PYY7 DNA topoisomerase III, putative n=1 Tax=Ixodes scapularis
RepID=B7PYY7_IXOSC
Length = 670
Score = 85.9 bits (211), Expect(2) = 6e-20
Identities = 47/134 (35%), Positives = 75/134 (55%), Gaps = 4/134 (2%)
Frame = +3
Query: 57 ETKMAPKVLMVAEKPSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTS 227
E K +VL VAEK A +++ ++S G R G + +++EF+ + +TS
Sbjct: 42 EFKPGMRVLNVAEKNDAAKNLSEIMSRGSYRRRDGLSVYNKIYEFDYNLFNTNCKMVMTS 101
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAH-ICRHLNQEARGCRFLVLWL 404
V GH+ +++F Y+ W + P++LF A V+ + + I L +E R C LV+W
Sbjct: 102 VSGHLLTLEFVSDYRKWHSCSPVELFHAPVIMSCGDKNYEKIKETLEKEIRYCDALVIWT 161
Query: 405 DCDREGENICFEVI 446
DCDREGENI F++I
Sbjct: 162 DCDREGENIGFQII 175
Score = 35.8 bits (81), Expect(2) = 6e-20
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS +T + V +A NL P+ AV+ R+E+D
Sbjct: 188 YRARFSEITPQAVARACQNLADPDPKLNAAVEVRRELD 225
[203][TOP]
>UniRef100_C5LNS3 Prokaryotic dna topoisomerase, putative n=1 Tax=Perkinsus marinus
ATCC 50983 RepID=C5LNS3_9ALVE
Length = 605
Score = 75.9 bits (185), Expect(2) = 6e-20
Identities = 45/126 (35%), Positives = 66/126 (52%), Gaps = 1/126 (0%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVD 254
+ L VAEK S+A + VL G + P VT+V GH+ +D
Sbjct: 15 RALNVAEKNSVAREMCRVLGGGVIPNGN--------------PPVMMVVTAVRGHLMGLD 60
Query: 255 FPGKYQD-WSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
F +Y+ W DP L+ A ++K+ ++ + +L + AR C +LVLWLDCDREGE I
Sbjct: 61 FEQEYRGRWDTVDPETLYNAPLVKSVASDMGPVAGNLRRLARTCDWLVLWLDCDREGEAI 120
Query: 432 CFEVIQ 449
+EVI+
Sbjct: 121 AYEVIE 126
Score = 45.8 bits (107), Expect(2) = 6e-20
Identities = 23/38 (60%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T D+ +A NL RPN A AVDARQEID
Sbjct: 138 YRANFSALTHADLTRACLNLARPNPHLAAAVDARQEID 175
[204][TOP]
>UniRef100_B6A9W0 DNA topoisomerase n=1 Tax=Cryptosporidium muris RN66
RepID=B6A9W0_9CRYT
Length = 843
Score = 74.7 bits (182), Expect(2) = 2e-19
Identities = 47/130 (36%), Positives = 67/130 (51%), Gaps = 7/130 (5%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVL-----SHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHV 242
VL +AEK S+A IA L + + ++ + V F F GS + VTSV GH+
Sbjct: 55 VLCIAEKHSVAKEIAWCLCPQNQNPNYLNSKSKTNPVLSFPYYFEGSKCNMIVTSVRGHI 114
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQ--VLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
+ F ++ W DP+ L ++K S I ++L ++ L+LWLDCDR
Sbjct: 115 KQLKFDPRFSSWETVDPIVLLNLSTPLIKVVSEDCNDIAQNLKHYSKLASTLILWLDCDR 174
Query: 417 EGENICFEVI 446
EGENI FEVI
Sbjct: 175 EGENIAFEVI 184
Score = 45.4 bits (106), Expect(2) = 2e-19
Identities = 22/37 (59%), Positives = 30/37 (81%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS++T+ D+ A++NLV PNR + AV+ARQEID
Sbjct: 198 RARFSALTKSDIEGAMNNLVAPNRAMSDAVEARQEID 234
[205][TOP]
>UniRef100_UPI0001AE62D7 UPI0001AE62D7 related cluster n=1 Tax=Homo sapiens
RepID=UPI0001AE62D7
Length = 132
Score = 99.4 bits (246), Expect = 2e-19
Identities = 54/107 (50%), Positives = 65/107 (60%), Gaps = 4/107 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCR 386
+DF GKY W DP +LF QA K E+NPK Q A G R
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLPQASVCTQAAPGVR 110
[206][TOP]
>UniRef100_B4E3E0 cDNA FLJ57454, highly similar to DNA topoisomerase 3-beta-1 (EC
5.99.1.2) n=1 Tax=Homo sapiens RepID=B4E3E0_HUMAN
Length = 132
Score = 99.4 bits (246), Expect = 2e-19
Identities = 54/107 (50%), Positives = 65/107 (60%), Gaps = 4/107 (3%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
VLMVAEKPS+A SIA +LS G + + KG + VHE+ G F G P FK+TSV GHV +
Sbjct: 4 VLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMT 63
Query: 249 VDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCR 386
+DF GKY W DP +LF QA K E+NPK Q A G R
Sbjct: 64 LDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLPQASVCTQAAPGVR 110
[207][TOP]
>UniRef100_Q4Q199 DNA topoisomerase n=1 Tax=Leishmania major RepID=Q4Q199_LEIMA
Length = 947
Score = 82.0 bits (201), Expect(2) = 2e-19
Identities = 53/127 (41%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE-FEGKFLGSPAHFKVTSVIGHVFS 248
P L VAEKPS+A +A LS G T + + +E KF G VTSV GH+
Sbjct: 2 PTWLNVAEKPSVAKEMAQSLSGGNCRTVPSQSRFNPVYEFKFEGKT--MLVTSVAGHLME 59
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
FP ++WS LF A + K + ++L A LVLWLDCDREGEN
Sbjct: 60 DQFPPNTKNWSTYPFQGLFSAPITKYVRADLEPVKKNLEALAGRADTLVLWLDCDREGEN 119
Query: 429 ICFEVIQ 449
ICFEV+Q
Sbjct: 120 ICFEVMQ 126
Score = 37.7 bits (86), Expect(2) = 2e-19
Identities = 18/37 (48%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++T +D+L A+ NL P++ + AV+ARQE+D
Sbjct: 139 RAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMD 175
[208][TOP]
>UniRef100_A4IDA8 DNA topoisomerase n=1 Tax=Leishmania infantum RepID=A4IDA8_LEIIN
Length = 947
Score = 82.0 bits (201), Expect(2) = 2e-19
Identities = 53/127 (41%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE-FEGKFLGSPAHFKVTSVIGHVFS 248
P L VAEKPS+A +A LS G T + + +E KF G VTSV GH+
Sbjct: 2 PTWLNVAEKPSVAKEMAQSLSGGNCRTVPSQSRFNPVYEFKFEGKT--MLVTSVAGHLME 59
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
FP ++WS LF A + K + ++L A LVLWLDCDREGEN
Sbjct: 60 DQFPPNTKNWSTYPFQGLFSAPITKYVRADLEPVKKNLEALAGRADTLVLWLDCDREGEN 119
Query: 429 ICFEVIQ 449
ICFEV+Q
Sbjct: 120 ICFEVMQ 126
Score = 37.7 bits (86), Expect(2) = 2e-19
Identities = 18/37 (48%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA FS++T +D+L A+ NL P++ + AV+ARQE+D
Sbjct: 139 RAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMD 175
[209][TOP]
>UniRef100_C5LAZ3 Prokaryotic dna topoisomerase, putative n=1 Tax=Perkinsus marinus
ATCC 50983 RepID=C5LAZ3_9ALVE
Length = 956
Score = 71.6 bits (174), Expect(2) = 1e-18
Identities = 34/78 (43%), Positives = 51/78 (65%), Gaps = 1/78 (1%)
Frame = +3
Query: 219 VTSVIGHVFSVDFPGKYQD-WSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLV 395
VT+V GH+ +DF +Y+ W DP L+ A ++K+ ++ + +L + AR C +LV
Sbjct: 282 VTAVRGHLMGLDFEQEYRGRWDTVDPETLYNAPLVKSVASDMGPVAGNLRRLARTCDWLV 341
Query: 396 LWLDCDREGENICFEVIQ 449
LWLDCDREGE I +EVI+
Sbjct: 342 LWLDCDREGEAIAYEVIE 359
Score = 45.8 bits (107), Expect(2) = 1e-18
Identities = 23/38 (60%), Positives = 27/38 (71%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRA FS++T D+ +A NL RPN A AVDARQEID
Sbjct: 371 YRANFSALTHADLTRACLNLARPNPHLAAAVDARQEID 408
[210][TOP]
>UniRef100_C5JDG2 DNA topoisomerase n=1 Tax=Ajellomyces dermatitidis SLH14081
RepID=C5JDG2_AJEDS
Length = 632
Score = 88.6 bits (218), Expect(2) = 1e-18
Identities = 53/132 (40%), Positives = 76/132 (57%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKFLGSP----AHFKVTS 227
MA KVL VAEKP+IA ++A LS G + + +G+ V +E F +P +TS
Sbjct: 1 MARKVLCVAEKPAIARAVAQHLSGGSSRAVSIRGNVYVKNYEFDFTFAPPWGQCSVTMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ S+DF +Y+ W++ P LF A V + + K I ++ AR + L +W D
Sbjct: 61 VIGHLTSLDFDSQYRSWNSCPPGRLFDAPVTDSVAKDKLSIAENIRTLARQSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 28.9 bits (63), Expect(2) = 1e-18
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ +L+A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHILQAAQNPIELDDSQANAVAARIELD 183
[211][TOP]
>UniRef100_C5GXA3 DNA topoisomerase n=1 Tax=Ajellomyces dermatitidis ER-3
RepID=C5GXA3_AJEDR
Length = 632
Score = 88.6 bits (218), Expect(2) = 1e-18
Identities = 53/132 (40%), Positives = 76/132 (57%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKFLGSP----AHFKVTS 227
MA KVL VAEKP+IA ++A LS G + + +G+ V +E F +P +TS
Sbjct: 1 MARKVLCVAEKPAIARAVAQHLSGGSSRAVSIRGNVYVKNYEFDFTFAPPWGQCSVTMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ S+DF +Y+ W++ P LF A V + + K I ++ AR + L +W D
Sbjct: 61 VIGHLTSLDFDSQYRSWNSCPPGRLFDAPVTDSVAKDKLSIAENIRTLARQSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 28.9 bits (63), Expect(2) = 1e-18
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ +L+A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHILQAAQNPIELDDSQANAVAARIELD 183
[212][TOP]
>UniRef100_A2DNF5 DNA topoisomerase n=1 Tax=Trichomonas vaginalis G3
RepID=A2DNF5_TRIVA
Length = 662
Score = 79.3 bits (194), Expect(2) = 2e-18
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 3/129 (2%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHE---FEGKFLGSPAHFKVTSVIG 236
M K+L VAEKPS+A A +LS+G M T+KG ++ + F+ F G TSV G
Sbjct: 1 MPKKILCVAEKPSVAREAAKILSNGHMETKKGKSKFNNNFVFQRDFQGEDVKVVFTSVAG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
HV + FP + ++W LF Q+ + + +L +A+ + LWLD DR
Sbjct: 61 HVLNYCFPPECKNWQTFGNTKLFDCQLNTCITANMEKVVGNLQTQAKKAFLVFLWLDNDR 120
Query: 417 EGENICFEV 443
EGE I EV
Sbjct: 121 EGEGISEEV 129
Score = 37.4 bits (85), Expect(2) = 2e-18
Identities = 17/39 (43%), Positives = 27/39 (69%)
Frame = +1
Query: 475 FYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ RARFS ++ ++++ A +N NR++A AV RQEID
Sbjct: 142 YKRARFSGLSPREIIHAFNNPTPINRNDAAAVKLRQEID 180
[213][TOP]
>UniRef100_A2QNT8 DNA topoisomerase n=1 Tax=Aspergillus niger CBS 513.88
RepID=A2QNT8_ASPNC
Length = 629
Score = 89.4 bits (220), Expect(2) = 2e-18
Identities = 52/131 (39%), Positives = 80/131 (61%), Gaps = 6/131 (4%)
Frame = +3
Query: 69 APKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEV--HEFEGKFLGS--PAHFKVTSV 230
A +VL VAEKP+IA ++A LS G Q +G+ V + F+ F GS +TSV
Sbjct: 3 AQRVLCVAEKPAIAKAVAQHLSGGSFQTIAIRGNQYVKNYVFDFNFGGSWGTCSVTMTSV 62
Query: 231 IGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDC 410
IGH+ +DF +Y+ W + P LF+A V ++ ++ K I +++ ++AR C+ L +W DC
Sbjct: 63 IGHLTGLDFERQYRTWLSCPPSALFEAPVHESVADDKVAIAKNIQEQARRCKALFIWTDC 122
Query: 411 DREGENICFEV 443
DREGE+I E+
Sbjct: 123 DREGEHIGTEI 133
Score = 27.3 bits (59), Expect(2) = 2e-18
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ + VL A +L+ + +A AV AR E+D
Sbjct: 148 RARFSNTEKAHVLHAARSLIELDDLQANAVAARIELD 184
[214][TOP]
>UniRef100_A7AMD4 DNA topoisomerase family protein n=1 Tax=Babesia bovis
RepID=A7AMD4_BABBO
Length = 633
Score = 89.0 bits (219), Expect(2) = 2e-18
Identities = 52/126 (41%), Positives = 70/126 (55%), Gaps = 3/126 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVFS 248
VL VAEKPS+A SI+ +LS G+M + + V+ F G TSV GH+
Sbjct: 4 VLNVAEKPSVARSISDILSGGRMRSEMSNARTNPVYSFTAPLEGRHCKMYFTSVRGHLME 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGEN 428
+DF +Y++W T LF A + S+ I ++L AR C LVLWLDCDREGE
Sbjct: 64 IDFDARYRNWQRTPIESLFCAPIQAAVSSNCKDIEKNLLHYARMCSKLVLWLDCDREGEA 123
Query: 429 ICFEVI 446
I +EV+
Sbjct: 124 IAYEVM 129
Score = 27.3 bits (59), Expect(2) = 2e-18
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 11/58 (18%)
Frame = +1
Query: 451 QLVSM*MMFYRARFSSVTEKDVLKALD-----------NLVRPNRDEALAVDARQEID 591
Q V+ + RA FS+VT + LD L PN + A AV+ARQEID
Sbjct: 133 QRVNSAIAIRRAIFSAVTRWSFICDLDVVGHEIETACATLREPNPNLAQAVEARQEID 190
[215][TOP]
>UniRef100_A1CF66 DNA topoisomerase n=1 Tax=Aspergillus clavatus RepID=A1CF66_ASPCL
Length = 629
Score = 87.0 bits (214), Expect(2) = 2e-18
Identities = 50/130 (38%), Positives = 75/130 (57%), Gaps = 6/130 (4%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTR--KGSTEVHEFEGKF-LGSP---AHFKVTSVI 233
P++L VAEKP+IA ++A LS G M T +G+ V + +F G P +TSV+
Sbjct: 4 PRILCVAEKPAIAKAVAQHLSGGSMRTISIRGNQYVKNYLFEFNFGDPWGTCSVTMTSVL 63
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ ++DF +Y+ W + P LF+A V + K I ++ +AR + L +W DCD
Sbjct: 64 GHLMALDFESQYKGWQSCPPGSLFEAPVHEYVETDKQPIAENIRDQARASKALFIWTDCD 123
Query: 414 REGENICFEV 443
REGE+I EV
Sbjct: 124 REGEHIGTEV 133
Score = 29.3 bits (64), Expect(2) = 2e-18
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL+A L+ + ++A AV AR E+D
Sbjct: 148 RARFSNTERAHVLRAARALIDVDENQANAVAARIELD 184
[216][TOP]
>UniRef100_UPI000155473E PREDICTED: similar to p70 ribosomal S6 kinase alpha-I n=1
Tax=Ornithorhynchus anatinus RepID=UPI000155473E
Length = 1042
Score = 78.6 bits (192), Expect(2) = 5e-18
Identities = 47/127 (37%), Positives = 73/127 (57%), Gaps = 5/127 (3%)
Frame = +3
Query: 81 LMVAEK--PSIALSIASVLSHGQMFTRKGST---EVHEFEGKFLGSPAHFKVTSVIGHVF 245
L VAE+ P + + S + G R+G + +++EF+ G +TSV GH+
Sbjct: 79 LCVAERFWPLVGIMRGSAAAPGPR-PREGFSRFNKIYEFDYHLYGQNVTMVMTSVSGHLL 137
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ DF +++ W + +PL LF+A++ K I R L +EA+ C+ L++W DCDREGE
Sbjct: 138 AHDFQMQFRKWQSCNPLILFEAEIEKYCPENFVDIKRTLEREAQQCQTLMIWTDCDREGE 197
Query: 426 NICFEVI 446
NI FEVI
Sbjct: 198 NIGFEVI 204
Score = 36.6 bits (83), Expect(2) = 5e-18
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ +RARFS +T + V A + L P++ + AVD RQE+D
Sbjct: 214 LQVFRARFSEITPRAVQLACETLTEPDQRVSDAVDVRQELD 254
[217][TOP]
>UniRef100_C9SVD2 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SVD2_9PEZI
Length = 658
Score = 80.9 bits (198), Expect(2) = 5e-18
Identities = 47/130 (36%), Positives = 73/130 (56%), Gaps = 6/130 (4%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGS---TEVHEFEGKFLGSP---AHFKVTSVIG 236
+VL VAEKPSI+ ++ LS GQ TR + T+ + F F G P +T+V G
Sbjct: 2 RVLCVAEKPSISKAVTDHLSGGQAQTRNTNDRFTKNYCFNFNF-GPPWNQCDVTMTAVRG 60
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ ++F ++W P LF A ++ ++ K + ++ Q+AR C L++W DCDR
Sbjct: 61 HLLGMEFTPANKNWQYPPPDSLFHAPIVTTVASDKKAVADNIEQQARYCDLLIIWTDCDR 120
Query: 417 EGENICFEVI 446
EGENI E++
Sbjct: 121 EGENIGREIV 130
Score = 34.3 bits (77), Expect(2) = 5e-18
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS++ V++A NLV + +A AVDAR E+D
Sbjct: 144 RAKFSNIERTHVIQAAKNLVDLDERQADAVDARMELD 180
[218][TOP]
>UniRef100_UPI00006CC0A9 DNA topoisomerase family protein n=1 Tax=Tetrahymena thermophila
RepID=UPI00006CC0A9
Length = 1049
Score = 82.4 bits (202), Expect(2) = 7e-18
Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 5/127 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
++L VAEKPS+A I+ VL +G T ++ V +FE K + TSV GH+
Sbjct: 3 QILNVAEKPSVAKEISRVLGNGSQKTLDSESKYNPVFQFEYKLKQEQVNMLFTSVTGHLI 62
Query: 246 SVDFPGKYQDWSATDPLDLFQ--AQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
S F K+++W + +P L +++LK + K I R+L + AR L+LWLDCDRE
Sbjct: 63 SQKFDDKFKNWKSFNPSVLLDQSSEILKFVESDKISIQRNLIKWARQVDTLILWLDCDRE 122
Query: 420 GENICFE 440
GE I +E
Sbjct: 123 GEAIAYE 129
Score = 32.3 bits (72), Expect(2) = 7e-18
Identities = 16/39 (41%), Positives = 26/39 (66%)
Frame = +1
Query: 475 FYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+ RA FSS+ +V A++NL P ++ + AV++R EID
Sbjct: 128 YERAWFSSLDRLNVTNAINNLRDPRKELSEAVESRMEID 166
[219][TOP]
>UniRef100_C1H2W6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H2W6_PARBA
Length = 632
Score = 87.0 bits (214), Expect(2) = 7e-18
Identities = 53/132 (40%), Positives = 74/132 (56%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTR--KGSTEVHEFEGKFLGSP----AHFKVTS 227
MA K+L VAEKP+IA ++A LS G + T +G+ V +E F +P VTS
Sbjct: 1 MARKILCVAEKPAIAKAVAQHLSGGALRTLSIRGNVFVKNYEFDFTFAPPWGRCSVTVTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ +DF +Y+ W++ P LF A V + K I ++ AR + L +W D
Sbjct: 61 VIGHLTGLDFDSQYRGWNSCPPGRLFDAPVQVSVPKDKQKIAENIQTLARHSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 27.7 bits (60), Expect(2) = 7e-18
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHVLHAATNPIELDEFQANAVAARIELD 183
[220][TOP]
>UniRef100_UPI000187E20F hypothetical protein MPER_12103 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187E20F
Length = 421
Score = 93.6 bits (231), Expect = 1e-17
Identities = 47/124 (37%), Positives = 75/124 (60%), Gaps = 1/124 (0%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE-VHEFEGKFLGSPAHFKVTSVIGHVFSV 251
+VL VAEKPSIA SI +LS G+ TR + + + +++ + + +HF VT+V GH+ +
Sbjct: 2 RVLCVAEKPSIAKSITQILSGGRFQTRNTAVKYIKDYDFDYPQTRSHFTVTAVAGHLTEL 61
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF ++ W + DP DLF A + + + R++ EA+ L++W DCDREGE+I
Sbjct: 62 DFTDTHRKWGSCDPFDLFDAPTVSRVKDDNKGMERNIFNEAKQAATLMIWTDCDREGEHI 121
Query: 432 CFEV 443
E+
Sbjct: 122 GSEI 125
[221][TOP]
>UniRef100_Q5CNR5 DNA topoisomerase III n=1 Tax=Cryptosporidium hominis
RepID=Q5CNR5_CRYHO
Length = 498
Score = 78.2 bits (191), Expect(2) = 1e-17
Identities = 47/130 (36%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVL-----SHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHV 242
+L VAEK S+A IA++L S ++ ++ + F KF G + VTSV GH+
Sbjct: 48 ILCVAEKNSVAKEIANILCPEFQSPNRLKSKSTTNVALYFPYKFCGEECNMIVTSVRGHL 107
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQ--VLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
+ F KY DW + +P+ L V+ + I +L ++ +L+LWLDCDR
Sbjct: 108 KQLGFASKYSDWGSVNPVVLLDLSTPVISSILPDCMGIADNLTYFSKISSYLILWLDCDR 167
Query: 417 EGENICFEVI 446
EGENI FEV+
Sbjct: 168 EGENIAFEVL 177
Score = 35.8 bits (81), Expect(2) = 1e-17
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
++ +RA FS++T+ ++ A+ L PNR + AV+AR+EID
Sbjct: 187 LITFRAHFSAITKFEINNAMKKLSFPNRALSDAVEARKEID 227
[222][TOP]
>UniRef100_UPI000012109F hypothetical protein CBG13326 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI000012109F
Length = 753
Score = 75.5 bits (184), Expect(2) = 3e-17
Identities = 42/128 (32%), Positives = 69/128 (53%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+ L VAEK +A +A++LS+G ++G ++ ++ + G A VTSV GH+
Sbjct: 3 RALFVAEKNDVAKGVAAILSNGTSNRKEGKSKFNKIYTLNSELFGQRAAISVTSVSGHLM 62
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ F +W T ++LF+A V + I + L +EA+ LV+W DCDREGE
Sbjct: 63 NWQFHENMSNWQTTSMVELFEAPVRHVVTPDMKLIEKTLREEAQRHDVLVVWTDCDREGE 122
Query: 426 NICFEVIQ 449
I E+++
Sbjct: 123 AIGAEIVK 130
Score = 37.4 bits (85), Expect(2) = 3e-17
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
YRARFS +T+ + +A NL+R + AVD R E+D
Sbjct: 142 YRARFSEITKAAITRAARNLIRLDEKIVAAVDCRSELD 179
[223][TOP]
>UniRef100_C1GBF3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GBF3_PARBD
Length = 632
Score = 85.1 bits (209), Expect(2) = 3e-17
Identities = 51/132 (38%), Positives = 74/132 (56%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTR--KGSTEVHEFEGKFLGSP----AHFKVTS 227
MA K+L VAEKP+IA ++A LS G + T +G+ V +E F +P +TS
Sbjct: 1 MARKILCVAEKPAIAKAVAQHLSGGALRTLSIRGNVFVKNYEFDFTFAPPWGRCSVTMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ +DF +Y+ W++ P LF A V + K I ++ AR + + +W D
Sbjct: 61 VIGHLTGLDFDSQYRGWNSCPPGRLFDAPVQVSVPKDKQKIAENIQTLARHSKAIFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 27.7 bits (60), Expect(2) = 3e-17
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHVLHAATNPIELDEFQANAVAARIELD 183
[224][TOP]
>UniRef100_C6H6Z0 DNA topoisomerase n=1 Tax=Ajellomyces capsulatus H143
RepID=C6H6Z0_AJECH
Length = 630
Score = 84.3 bits (207), Expect(2) = 3e-17
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKFLGSPAHFK----VTS 227
MA K+L VAEKP+IA +A LS G ++ + +G+ V +E F +P + +TS
Sbjct: 1 MARKILCVAEKPAIARVVAQHLSGGSSRVVSIRGNVFVKNYEFDFTFAPPWGQCSVIMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ S++F +Y+ W++ P LF A V+ + + I ++ AR + L +W D
Sbjct: 61 VIGHLTSLEFDSRYRGWNSCPPGRLFDAPVVDSVAKDNLTIAENIRTLARNSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 28.5 bits (62), Expect(2) = 3e-17
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ +L+A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHILQAATNPIELDDSQANAVAARIELD 183
[225][TOP]
>UniRef100_A3FQH8 DNA topoisomerase III, putative n=1 Tax=Cryptosporidium parvum Iowa
II RepID=A3FQH8_CRYPV
Length = 814
Score = 76.6 bits (187), Expect(2) = 3e-17
Identities = 46/130 (35%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVL-----SHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHV 242
+L VAEK S+A IA++L S ++ ++ + F +F G + VTSV GH+
Sbjct: 47 ILCVAEKNSVAKEIANILCPEFQSPNKLKSKSKTNVALYFPYEFCGDECNMIVTSVRGHL 106
Query: 243 FSVDFPGKYQDWSATDPLDLFQAQ--VLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
+ F KY DW + +P+ L V+ + I +L ++ +L+LWLDCDR
Sbjct: 107 KQLGFASKYSDWGSVNPVVLLDLSTPVISSILPDCMGIADNLTYFSKISSYLILWLDCDR 166
Query: 417 EGENICFEVI 446
EGENI FEV+
Sbjct: 167 EGENIAFEVL 176
Score = 35.8 bits (81), Expect(2) = 3e-17
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +1
Query: 469 MMFYRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
++ +RA FS++T+ ++ A+ L PNR + AV+AR+EID
Sbjct: 186 LITFRAHFSAITKFEINNAMKKLSFPNRALSDAVEARKEID 226
[226][TOP]
>UniRef100_C4VAL6 Putative uncharacterized protein n=1 Tax=Nosema ceranae BRL01
RepID=C4VAL6_NOSCE
Length = 805
Score = 69.7 bits (169), Expect(2) = 4e-17
Identities = 38/122 (31%), Positives = 67/122 (54%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDF 257
+L +AEKPS+A SI+ +LS + +R K+ F TSV+GH+++++F
Sbjct: 3 ILNIAEKPSVAKSISKILSQSIVTSRGRHKYCPNITFKYNNDT--FTFTSVLGHIYNLNF 60
Query: 258 PGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICF 437
KY W + DP LF + K ++ ++L +++ +++W DCDREGE+I
Sbjct: 61 CKKYI-WESIDPKILFYEPLTKKIQEDFINLQKNLEEQSYKANKVIIWTDCDREGEHIAQ 119
Query: 438 EV 443
++
Sbjct: 120 QI 121
Score = 42.4 bits (98), Expect(2) = 4e-17
Identities = 20/37 (54%), Positives = 28/37 (75%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARF++++ DV +AL+NLV N +EA AVD R E+D
Sbjct: 135 RARFNAISRNDVTRALENLVNININEADAVDCRMEMD 171
[227][TOP]
>UniRef100_B8CGH9 DNA topoisomerase n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CGH9_THAPS
Length = 1417
Score = 91.3 bits (225), Expect = 5e-17
Identities = 52/122 (42%), Positives = 71/122 (58%), Gaps = 9/122 (7%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAH---------FKVTSV 230
V+ +AEKPSIA ++A LS G T+ G + +E F P + +VTSV
Sbjct: 645 VVHIAEKPSIAQAVAQGLSDGGD-TKSGGKGLPTYE--FTNPPFNKAPQASKVTHRVTSV 701
Query: 231 IGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDC 410
GHVF+VDFP +YQ W + DP +LF A V++ K + RHL A+G F+VLW+DC
Sbjct: 702 AGHVFNVDFPSEYQSWDSVDPAELFHAPVVRKPC--KGSVVRHLQDVAKGVDFIVLWMDC 759
Query: 411 DR 416
DR
Sbjct: 760 DR 761
[228][TOP]
>UniRef100_A9V1D2 DNA topoisomerase n=1 Tax=Monosiga brevicollis RepID=A9V1D2_MONBE
Length = 1562
Score = 82.4 bits (202), Expect(2) = 5e-17
Identities = 57/145 (39%), Positives = 80/145 (55%), Gaps = 8/145 (5%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEVH--EFEGKFLGSPAHFKVTSVIGHVFS 248
KVLMVAEKP++A IA +L+ G T V +F K G P + K+TSV+GH+ +
Sbjct: 5 KVLMVAEKPTVAKGIAQILAPGCRREATNCTYVGLWDFNIKIEGRPCNVKLTSVLGHLMT 64
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPK------AHICRHLNQEARGCRFLVLWLDC 410
+F Y+ W + P +LF A L++ N + A I L + AR C +L++ D
Sbjct: 65 WEFKDAYRGWHSCAPQELFDAP-LQHVVNDRPGETNCATIKTLLQKYARTCDWLIIATDN 123
Query: 411 DREGENICFEVIQSTGFNVNDVLSC 485
DREGENI FE+I+ VN L C
Sbjct: 124 DREGENIGFEIIEVCR-RVNRNLDC 147
Score = 29.3 bits (64), Expect(2) = 5e-17
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
R +FS+VT ++ L LV P++ + A ARQE+D
Sbjct: 149 RMKFSAVTPGEINGCLTRLVPPDQRASQACVARQELD 185
[229][TOP]
>UniRef100_A6R6R2 DNA topoisomerase n=1 Tax=Ajellomyces capsulatus NAm1
RepID=A6R6R2_AJECN
Length = 632
Score = 83.2 bits (204), Expect(2) = 6e-17
Identities = 50/132 (37%), Positives = 76/132 (57%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKFLGSPAHFK----VTS 227
MA K+L VAEKP+IA +A LS G + + +G+ V +E F +P + +TS
Sbjct: 1 MARKILCVAEKPAIARVVAQHLSGGSSRAVSIRGNVFVKNYEFDFTFAPPWGQCSVIMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
V+GH+ S+DF +Y+ W++ P LF A V+ + + I ++ AR + L +W D
Sbjct: 61 VLGHLTSLDFDSQYRGWNSCPPGLLFDAPVVDSVAKDNLTIAENIRTLARNSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 28.5 bits (62), Expect(2) = 6e-17
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ +L+A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHILQAATNPIELDDSQANAVAARIELD 183
[230][TOP]
>UniRef100_B8NFR2 DNA topoisomerase n=2 Tax=Aspergillus RepID=B8NFR2_ASPFN
Length = 629
Score = 85.1 bits (209), Expect(2) = 6e-17
Identities = 50/130 (38%), Positives = 77/130 (59%), Gaps = 6/130 (4%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKF-LGSP---AHFKVTSVI 233
P+VL VAEKP+IA +++ LS G Q +G+ V + F G P +TSVI
Sbjct: 4 PRVLCVAEKPAIAKAVSQHLSGGSFQTIPVRGNQYVKNYVFDFNFGGPWGTCSVTMTSVI 63
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ +++F +Y+ W + P LF+A V + KA I +++ ++A+ C+ L +W DCD
Sbjct: 64 GHLTTLEFERQYKGWLSCPPGALFEAPVHITVDSDKAAIAKNIQEQAKYCKALFIWTDCD 123
Query: 414 REGENICFEV 443
REGE+I EV
Sbjct: 124 REGEHIGTEV 133
Score = 26.6 bits (57), Expect(2) = 6e-17
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+ + VL A +L+ + +A AV AR E+D
Sbjct: 148 RAKFSNTEKAHVLNAARSLIELDDLQANAVAARIELD 184
[231][TOP]
>UniRef100_C5PFM2 DNA topoisomerase n=1 Tax=Coccidioides posadasii C735 delta SOWgp
RepID=C5PFM2_COCP7
Length = 618
Score = 86.3 bits (212), Expect(2) = 6e-17
Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTR--KGSTEVHEFEGKFLGSP----AHFKVTS 227
M ++L VAEKP+IA ++A LS G + T +G+ V +E +F P + +TS
Sbjct: 1 MGARILCVAEKPAIAKAVAQHLSGGALRTVAIRGNQYVKNYEFQFSFGPPWGNSSVTMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ ++DF +++ W + P LF A V+ + K I ++ +AR L +W D
Sbjct: 61 VIGHLTALDFESEWRHWQSCPPGQLFDAPVVNDVDKDKIGIAENIRNKARQADALFIWTD 120
Query: 408 CDREGENICFEV-IQSTGFN 464
CDREGE+I EV Q+ G N
Sbjct: 121 CDREGEHIGSEVRTQAVGAN 140
Score = 25.4 bits (54), Expect(2) = 6e-17
Identities = 14/37 (37%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+ VL+A N + + + AV AR E+D
Sbjct: 147 RAKFSNTERAHVLRAARNPIALDERQINAVAARIELD 183
[232][TOP]
>UniRef100_C0NGZ5 DNA topoisomerase n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NGZ5_AJECG
Length = 630
Score = 83.6 bits (205), Expect(2) = 7e-17
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHG--QMFTRKGSTEVHEFEGKFLGSPAHFK----VTS 227
MA K+L VAEKP+IA +A LS G ++ + +G+ V +E F +P + +TS
Sbjct: 1 MARKILCVAEKPAIARVVAQHLSGGSSRVVSIRGNVFVKNYEFDFTFAPPWGQCSVIMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ S++F +Y+ W++ P LF A V+ + + I ++ AR + L +W D
Sbjct: 61 VIGHLTSLEFDSQYRGWNSCPPGRLFDAPVVDSVAKNNLTIAENIRTLARNSKALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGTEV 132
Score = 27.7 bits (60), Expect(2) = 7e-17
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ +L+A N + + +A AV AR E+D
Sbjct: 147 RARFSNTERAHILQAATNPIDLDDSQANAVAARIELD 183
[233][TOP]
>UniRef100_A7QN70 Chromosome undetermined scaffold_131, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QN70_VITVI
Length = 199
Score = 90.5 bits (223), Expect = 9e-17
Identities = 39/54 (72%), Positives = 46/54 (85%)
Frame = +3
Query: 303 FQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICFEVIQSTGFN 464
FQA + K ESNPKAHIC+ L+QEAR C LVLWLDCDREG+NICFEV++ TGF+
Sbjct: 15 FQASIHKAESNPKAHICKRLSQEARDCGHLVLWLDCDREGDNICFEVVECTGFH 68
[234][TOP]
>UniRef100_B8M6R0 DNA topoisomerase n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8M6R0_TALSN
Length = 660
Score = 84.0 bits (206), Expect(2) = 9e-17
Identities = 50/129 (38%), Positives = 77/129 (59%), Gaps = 6/129 (4%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRK--GSTEV--HEFEGKFLGSPAHFKVT--SVIG 236
++L VAEKP+IA ++A LS G M T G V + F F G+ + +VT SVIG
Sbjct: 5 RILCVAEKPAIAKAVAQHLSGGSMQTMNIHGQQYVKNYVFSFNFGGAWGNCEVTMTSVIG 64
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ ++F +Y+ W++ P LF+ V +N + K I ++ ++A+ C+ L +W DCDR
Sbjct: 65 HLTGLEFGKEYKGWTSCPPSLLFEVPVFENVDSDKLSIADNIKKQAQYCKALFIWTDCDR 124
Query: 417 EGENICFEV 443
EGE+I EV
Sbjct: 125 EGEHIGTEV 133
Score = 26.9 bits (58), Expect(2) = 9e-17
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL+A + + +A AV AR E+D
Sbjct: 148 RARFSNTERAHVLRAAREPIELDEKQANAVAARIELD 184
[235][TOP]
>UniRef100_B0XU08 DNA topoisomerase n=2 Tax=Aspergillus fumigatus RepID=B0XU08_ASPFC
Length = 629
Score = 82.8 bits (203), Expect(2) = 9e-17
Identities = 49/130 (37%), Positives = 74/130 (56%), Gaps = 6/130 (4%)
Frame = +3
Query: 72 PKVLMVAEKPSIALSIASVLSHGQMFTRK--GSTEVHEFEGKF-LGSP---AHFKVTSVI 233
P++L VAEKP+IA ++A LS G M T G+ V + +F G P +TSV+
Sbjct: 4 PRILCVAEKPAIAKAVAQHLSGGSMQTISIHGNKYVKNYLFEFNFGDPWGTCSVTMTSVL 63
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ ++DF +Y+ W + P LF+A V + I ++ ++AR + L +W DCD
Sbjct: 64 GHLMALDFESQYKSWLSCPPGALFEAPVREFVEEDNKPIAENIKEQARMSKALFIWTDCD 123
Query: 414 REGENICFEV 443
REGE+I EV
Sbjct: 124 REGEHIGTEV 133
Score = 28.1 bits (61), Expect(2) = 9e-17
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL+A L + ++A AV AR E+D
Sbjct: 148 RARFSNTERAHVLRAARALTDVDENQANAVAARIELD 184
[236][TOP]
>UniRef100_A8B577 DNA topoisomerase III n=1 Tax=Giardia lamblia ATCC 50803
RepID=A8B577_GIALA
Length = 973
Score = 71.6 bits (174), Expect(2) = 1e-16
Identities = 44/124 (35%), Positives = 61/124 (49%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKGSTEVHEFEGKFLGSPAHFKVTSVIGHVFSVDF 257
+L++AEKPSIA I+ G S + F F GS F TSV GHVF +DF
Sbjct: 2 ILLIAEKPSIAEMISRNYGEGAKKLDNVSFPTYTFVQSFEGSKETFMCTSVAGHVFEIDF 61
Query: 258 PGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENICF 437
+ S + V + ++ + + +HL L+L LD DREGENICF
Sbjct: 62 DAELNGSSVPQERLFERGHVHYSFTDSGSTVAKHLKSIGGKAMQLILCLDNDREGENICF 121
Query: 438 EVIQ 449
EV++
Sbjct: 122 EVLK 125
Score = 38.9 bits (89), Expect(2) = 1e-16
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+VT+ ++ A NL +P+++ + AV+ARQE+D
Sbjct: 139 RARFSAVTKAEIQNAFRNLDKPDQNLSDAVEARQELD 175
[237][TOP]
>UniRef100_B6Q6V1 DNA topoisomerase n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6Q6V1_PENMQ
Length = 662
Score = 83.2 bits (204), Expect(2) = 1e-16
Identities = 48/134 (35%), Positives = 76/134 (56%), Gaps = 11/134 (8%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLS---------HGQMFTRKGSTEVHEFEGKFLGSPAHFKVT- 224
++L VAEKP+IA ++A LS HGQ + + + F F G+ + +VT
Sbjct: 5 RILCVAEKPAIAKAVAQHLSGGSFQTINIHGQQYVKN-----YVFSFNFGGAWGNCEVTM 59
Query: 225 -SVIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLW 401
SVIGH+ ++F +Y+ W++ P LF+ V +N K I ++ ++A+ C+ L +W
Sbjct: 60 TSVIGHLTGLEFGKEYKGWTSCPPSLLFEVPVFENVDTDKLSIAENIKKQAQYCKALFIW 119
Query: 402 LDCDREGENICFEV 443
DCDREGE+I EV
Sbjct: 120 TDCDREGEHIGTEV 133
Score = 27.3 bits (59), Expect(2) = 1e-16
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL+A + + +A AV AR E+D
Sbjct: 148 RARFSNTERAHVLRAAREPIELDEKQASAVAARIELD 184
[238][TOP]
>UniRef100_Q4PAW5 DNA topoisomerase n=1 Tax=Ustilago maydis RepID=Q4PAW5_USTMA
Length = 1325
Score = 89.7 bits (221), Expect = 2e-16
Identities = 50/129 (38%), Positives = 76/129 (58%), Gaps = 5/129 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTEV---HEFEGKFLG--SPAHFKVTSVIGH 239
++L VAEKPSIA SIA++L+ G R G + ++F+ + G +TSV GH
Sbjct: 97 RILCVAEKPSIAKSIANILARGHASNRPGKDKFCRNYDFQYRMPGVQGMVDMTMTSVRGH 156
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ + DF +++ W + P DLFQA V+ N S+ I +L EAR +++W DCDRE
Sbjct: 157 LTNTDFGPQHKAWFSCPPADLFQAPVITNLSDDAKDIGTNLRLEARNADAVMIWTDCDRE 216
Query: 420 GENICFEVI 446
GE+I E++
Sbjct: 217 GEHIGSEIV 225
[239][TOP]
>UniRef100_Q5KAU9 DNA topoisomerase n=1 Tax=Filobasidiella neoformans
RepID=Q5KAU9_CRYNE
Length = 828
Score = 89.4 bits (220), Expect = 2e-16
Identities = 52/132 (39%), Positives = 75/132 (56%), Gaps = 8/132 (6%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE-VHEFEGKFLGSP-------AHFKVTSV 230
+VL VAEKPSIA SI +LS G+ TR G + + ++ + +P A+F VT+V
Sbjct: 2 RVLCVAEKPSIAKSITEILSGGRWDTRNGRHQYIRNYDFLYNLAPPLGNGRGANFTVTAV 61
Query: 231 IGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDC 410
+GH+ S DF ++ W + DP LF A V+ + +L EAR L++W DC
Sbjct: 62 LGHLTSSDFDDDHRKWGSCDPFALFDAPVITFVDQKLKTVESNLQIEARNADILMIWTDC 121
Query: 411 DREGENICFEVI 446
DREGE+I EV+
Sbjct: 122 DREGEHIGSEVV 133
[240][TOP]
>UniRef100_Q55KM2 DNA topoisomerase n=1 Tax=Filobasidiella neoformans
RepID=Q55KM2_CRYNE
Length = 1059
Score = 89.4 bits (220), Expect = 2e-16
Identities = 52/132 (39%), Positives = 75/132 (56%), Gaps = 8/132 (6%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE-VHEFEGKFLGSP-------AHFKVTSV 230
+VL VAEKPSIA SI +LS G+ TR G + + ++ + +P A+F VT+V
Sbjct: 2 RVLCVAEKPSIAKSITEILSGGRWDTRNGRHQYIRNYDFLYNLAPPLGNGRGANFTVTAV 61
Query: 231 IGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDC 410
+GH+ S DF ++ W + DP LF A V+ + +L EAR L++W DC
Sbjct: 62 LGHLTSSDFDDDHRKWGSCDPFALFDAPVITFVDQKLKTVESNLQIEARNADILMIWTDC 121
Query: 411 DREGENICFEVI 446
DREGE+I EV+
Sbjct: 122 DREGEHIGSEVV 133
[241][TOP]
>UniRef100_Q5DFL5 SJCHGC04238 protein n=1 Tax=Schistosoma japonicum
RepID=Q5DFL5_SCHJA
Length = 114
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/101 (44%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Frame = +3
Query: 78 VLMVAEKPSIALSIASVLSHGQMFTRKG---STEVHEFEGKFLGSPAHFKVTSVIGHVFS 248
V MVAEKPS+A SIA LS+ + +R+G + +HE+ G+F+ FK+TSV GHV +
Sbjct: 4 VFMVAEKPSLAESIAKSLSNKRNSSRRGFNLACSIHEWTGQFMSEQVRFKMTSVCGHVMN 63
Query: 249 VDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQE 371
VDF +Y W DP +LF A + K E+NPK + L E
Sbjct: 64 VDFLSRYNSWDKVDPAELFVAPIEKKEANPKLKMVDFLRHE 104
[242][TOP]
>UniRef100_C0S9B3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0S9B3_PARBP
Length = 710
Score = 81.3 bits (199), Expect(2) = 3e-16
Identities = 51/132 (38%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQMFTR--KGSTEVHEFEGKFLGSP----AHFKVTS 227
MA K+L VAEKP+IA ++A LS G + T +G+ V +E F +P +TS
Sbjct: 1 MARKILCVAEKPAIAKAVAQHLSGGALRTLSIRGNVFVKNYEFDFTFAPPWGRCSVTMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
VIGH+ +DF +Y+ W++ P LF A V K I ++ AR + + +W D
Sbjct: 61 VIGHLTGLDFDSQYRGWNSCPPGRLFDAPV-----QDKQKIAENIQTLARHSKAIFIWTD 115
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 116 CDREGEHIGTEV 127
Score = 27.7 bits (60), Expect(2) = 3e-16
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+ VL A N + + +A AV AR E+D
Sbjct: 142 RARFSNTERAHVLHAATNPIELDEFQANAVAARIELD 178
[243][TOP]
>UniRef100_A7F4Y0 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7F4Y0_SCLS1
Length = 670
Score = 83.6 bits (205), Expect(2) = 4e-16
Identities = 52/132 (39%), Positives = 77/132 (58%), Gaps = 6/132 (4%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQM---FTRKGSTEVHEFEGKFLGSPAHFK--VTSV 230
MAPK+L VAEKPSIA ++A+ L+ G TR + + F F G + +TSV
Sbjct: 1 MAPKILCVAEKPSIAKAVANHLAGGSAQASSTRNKYIKNYTFTFDFGGQWGNCNAVMTSV 60
Query: 231 IGHVFSVDFPGKYQDWSATDPLDLF-QAQVLKNESNPKAHICRHLNQEARGCRFLVLWLD 407
GH+ S+D ++ W+ P LF +A V+++ + K I +++ +ARG R L +W D
Sbjct: 61 SGHLTSLDVAPSHRSWTDPPPKSLFFEAPVIESIAEDKKVIAQNIESQARGARALFIWTD 120
Query: 408 CDREGENICFEV 443
CDREGE+I EV
Sbjct: 121 CDREGEHIGGEV 132
Score = 25.4 bits (54), Expect(2) = 4e-16
Identities = 14/37 (37%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS++ V++A + V ++ + AV AR E+D
Sbjct: 147 RARFSNIERAHVIQAAKHPVDLDQRQVDAVAARIELD 183
[244][TOP]
>UniRef100_A7TSV2 DNA topoisomerase n=1 Tax=Vanderwaltozyma polyspora DSM 70294
RepID=A7TSV2_VANPO
Length = 650
Score = 82.8 bits (203), Expect(2) = 4e-16
Identities = 48/132 (36%), Positives = 70/132 (53%), Gaps = 7/132 (5%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTR-KGSTEVHEFEGKFLGSP------AHFKVTSVI 233
+VL VAEK SIA +++ +LS G R G V ++ +F G P +TSV
Sbjct: 2 RVLCVAEKNSIAKAVSQILSGGNSNARDSGYMYVKNYDFRFNGFPFINDRDCDVTMTSVA 61
Query: 234 GHVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCD 413
GH+ +DFP W +LF A +L+ + I ++ +EAR FL++W DCD
Sbjct: 62 GHLMGIDFPNDRYGWGKCPVHELFDAPLLQVYDKNQKKIADNIKKEARNADFLMIWTDCD 121
Query: 414 REGENICFEVIQ 449
REGE I +E+ Q
Sbjct: 122 REGEYIGWEIFQ 133
Score = 26.2 bits (56), Expect(2) = 4e-16
Identities = 14/38 (36%), Positives = 20/38 (52%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RA FS + +L A N R + + AV+ R EID
Sbjct: 148 FRANFSHLERSHILYAARNPRRLDMNSVNAVETRMEID 185
[245][TOP]
>UniRef100_A8N7S6 DNA topoisomerase n=1 Tax=Coprinopsis cinerea okayama7#130
RepID=A8N7S6_COPC7
Length = 825
Score = 88.2 bits (217), Expect = 4e-16
Identities = 51/125 (40%), Positives = 71/125 (56%), Gaps = 1/125 (0%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE-VHEFEGKFLGSPAHFKVTSVIGHVFSV 251
+VL VAEKPSI+ SI +LS GQ T + + +E + + A F VT V GH+ S
Sbjct: 2 RVLCVAEKPSISKSITQILSGGQFRTTNTALGYIKNYEFDYPQTRATFVVTCVTGHLTST 61
Query: 252 DFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGENI 431
DF +++ W + DP LF A+V K I +L +AR L++W DCDREGE+I
Sbjct: 62 DFTEQHRGWHSCDPSALFDAEVQTFVPQDKKAIETNLKNQARYADMLMIWTDCDREGEHI 121
Query: 432 CFEVI 446
EV+
Sbjct: 122 GMEVV 126
[246][TOP]
>UniRef100_C7YNQ3 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YNQ3_NECH7
Length = 653
Score = 82.0 bits (201), Expect(2) = 5e-16
Identities = 47/131 (35%), Positives = 76/131 (58%), Gaps = 5/131 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFT---RKGSTEVHEFEGKF--LGSPAHFKVTSVIGH 239
+VL VAEKPSI+ ++A +LS G T R + + F+ F +T V GH
Sbjct: 2 RVLCVAEKPSISKAVAGILSGGSHTTHNTRNKFIKNYSFDFDFGQRWGKCSVTMTCVTGH 61
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ +VDF +Y++WS P LF A ++ ++ K I +++ +A+ R LV+W DCDRE
Sbjct: 62 LTNVDFSPEYKNWSHPPPEALFNAPIVTSD---KKSIAQNIESQAKFARLLVIWTDCDRE 118
Query: 420 GENICFEVIQS 452
GE+I E++++
Sbjct: 119 GEHIGHEIVEA 129
Score = 26.6 bits (57), Expect(2) = 5e-16
Identities = 15/37 (40%), Positives = 20/37 (54%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RARFS+V VL A +L + + AV R E+D
Sbjct: 141 RARFSNVERAHVLSAARSLAELDEKQVNAVATRIELD 177
[247][TOP]
>UniRef100_O61660 DNA topoisomerase 3 n=1 Tax=Caenorhabditis elegans RepID=TOP3_CAEEL
Length = 759
Score = 71.6 bits (174), Expect(2) = 6e-16
Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE---VHEFEGKFLGSPAHFKVTSVIGHVF 245
+ L VAEK +A +A++LS+G R+G ++ ++ + G VTSV GH+
Sbjct: 3 RALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGHMM 62
Query: 246 SVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDREGE 425
+ F +W ++LF+A V + I + L ++A+ LV+W DCDREGE
Sbjct: 63 NFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDREGE 122
Query: 426 NICFEVIQ 449
I E+++
Sbjct: 123 AIGAEIVK 130
Score = 36.6 bits (83), Expect(2) = 6e-16
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 478 YRARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
+RARFS +T+ + +A NL+R + AVD R E+D
Sbjct: 142 FRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELD 179
[248][TOP]
>UniRef100_C8V872 DNA topoisomerase III (Eurofung) n=2 Tax=Emericella nidulans
RepID=C8V872_EMENI
Length = 629
Score = 82.0 bits (201), Expect(2) = 6e-16
Identities = 48/129 (37%), Positives = 74/129 (57%), Gaps = 6/129 (4%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMFTRKGSTE------VHEFEGKFLGSPAHFKVTSVIG 236
KVL VAEKP+IA ++A LS G+M T+ + V +F + +TSV+G
Sbjct: 5 KVLCVAEKPAIAKAVAQHLSGGRMETKNVTGNRFVKNYVFDFNFGNQWGNSSVTMTSVLG 64
Query: 237 HVFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDR 416
H+ S++F +Y W++ P LF+A V + K I ++ ++A ++LV+W DCDR
Sbjct: 65 HLTSLEFERQYSGWASCPPAALFEAPVKIAVDDDKKAIANNIMKQATHSQYLVIWTDCDR 124
Query: 417 EGENICFEV 443
EGE+I EV
Sbjct: 125 EGEHIGTEV 133
Score = 26.2 bits (56), Expect(2) = 6e-16
Identities = 14/37 (37%), Positives = 23/37 (62%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+F++ + VL A +L+ + +A AV AR E+D
Sbjct: 148 RAKFNNTEKIHVLNAARSLIELDERQANAVAARIELD 184
[249][TOP]
>UniRef100_C5FLE2 DNA topoisomerase III n=1 Tax=Microsporum canis CBS 113480
RepID=C5FLE2_NANOT
Length = 631
Score = 84.7 bits (208), Expect(2) = 8e-16
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 16/142 (11%)
Frame = +3
Query: 66 MAPKVLMVAEKPSIALSIASVLSHGQM--FTRKGSTEVHEFEGKFLGSP----AHFKVTS 227
MAPK+L VAEKP+IA +A LS G++ F +G+ V +E F P +TS
Sbjct: 1 MAPKILCVAEKPAIAKLVAQHLSGGRLRTFNIEGNQYVKNYEFDFTFDPPWGSCSVVMTS 60
Query: 228 VIGHVFSVDFPGKYQDWSATDPLDLFQAQVLKNES----------NPKAHICRHLNQEAR 377
V+GH+ + +F +Y++WS+ +P LF A V+ + + K I +++ +AR
Sbjct: 61 VLGHLTTSEFEPRYRNWSSCNPSQLFDANVITSVDKVRILSRCAVHEKLGIAKNIKIQAR 120
Query: 378 GCRFLVLWLDCDREGENICFEV 443
+ L +W DCDREGE I EV
Sbjct: 121 YSKALFIWTDCDREGEYIGSEV 142
Score = 23.1 bits (48), Expect(2) = 8e-16
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA+FS+ VL+A + + + AV AR E+D
Sbjct: 157 RAKFSNTERTHVLQAARGPIGLDEQQVDAVAARIELD 193
[250][TOP]
>UniRef100_O60126 DNA topoisomerase 3 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP3_SCHPO
Length = 622
Score = 85.1 bits (209), Expect(2) = 8e-16
Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 5/128 (3%)
Frame = +3
Query: 75 KVLMVAEKPSIALSIASVLSHGQMF---TRKGSTEVHEFEGKFLGSPAHFKVT--SVIGH 239
+VL VAEK SIA S+AS+L G + TR + ++F F G+ VT SV GH
Sbjct: 2 RVLCVAEKNSIAKSVASILGGGHVRRRDTRSKYVKNYDFSFNFGGNVGSSDVTMTSVSGH 61
Query: 240 VFSVDFPGKYQDWSATDPLDLFQAQVLKNESNPKAHICRHLNQEARGCRFLVLWLDCDRE 419
+ FP +Y WS+ LF AQ++ + S + ++ +EAR ++L +W DCDRE
Sbjct: 62 LTEASFPSEYSSWSSVPQDVLFDAQIITSVSKNAEVLADNIKKEARNAQYLYIWTDCDRE 121
Query: 420 GENICFEV 443
GE+I E+
Sbjct: 122 GEHIGVEI 129
Score = 22.7 bits (47), Expect(2) = 8e-16
Identities = 12/37 (32%), Positives = 21/37 (56%)
Frame = +1
Query: 481 RARFSSVTEKDVLKALDNLVRPNRDEALAVDARQEID 591
RA F+++ ++ A +++ A AVDAR E+D
Sbjct: 144 RADFNNLERSHIISAAKRPRDVSKNAADAVDARIELD 180