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[1][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
          Length = 910

 Score =  122 bits (307), Expect = 9e-27
 Identities = 57/67 (85%), Positives = 63/67 (94%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD + KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKFTWAMD
Sbjct: 844  IEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 903

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 904  VDPSFRF 910

[2][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
            RepID=B9SSQ1_RICCO
          Length = 891

 Score =  122 bits (305), Expect = 2e-26
 Identities = 57/67 (85%), Positives = 63/67 (94%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+ +MK KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKFTWAMD
Sbjct: 825  IEKMELNMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 884

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 885  VDPQFRF 891

[3][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
           RepID=B9I1A0_POPTR
          Length = 860

 Score =  121 bits (304), Expect = 2e-26
 Identities = 57/67 (85%), Positives = 62/67 (92%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+  MK KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKFTWAMD
Sbjct: 794 IEKMELSMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 853

Query: 238 VXPDFRF 218
           V P FRF
Sbjct: 854 VDPQFRF 860

[4][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
          Length = 917

 Score =  121 bits (303), Expect = 3e-26
 Identities = 54/67 (80%), Positives = 64/67 (95%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RDM+ KED++TVALGTS+INY+DPRITVAWC+RH+VPIEKIFN+SLLAKF WAMD
Sbjct: 845  IEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMD 904

Query: 238  VXPDFRF 218
            V P+FRF
Sbjct: 905  VDPEFRF 911

[5][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
           thaliana RepID=Q8RXI5_ARATH
          Length = 232

 Score =  121 bits (303), Expect = 3e-26
 Identities = 54/67 (80%), Positives = 64/67 (95%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDM+ KED++TVALGTS+INY+DPRITVAWC+RH+VPIEKIFN+SLLAKF WAMD
Sbjct: 160 IEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMD 219

Query: 238 VXPDFRF 218
           V P+FRF
Sbjct: 220 VDPEFRF 226

[6][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
            RepID=Q84ZL5_ORYSJ
          Length = 916

 Score =  121 bits (303), Expect = 3e-26
 Identities = 56/67 (83%), Positives = 63/67 (94%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+ D K KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SL+AKF+WAMD
Sbjct: 850  IEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMD 909

Query: 238  VXPDFRF 218
            V PDFRF
Sbjct: 910  VDPDFRF 916

[7][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
            RepID=A2YRB7_ORYSI
          Length = 916

 Score =  121 bits (303), Expect = 3e-26
 Identities = 56/67 (83%), Positives = 63/67 (94%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+ D K KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SL+AKF+WAMD
Sbjct: 850  IEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMD 909

Query: 238  VXPDFRF 218
            V PDFRF
Sbjct: 910  VDPDFRF 916

[8][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
            RepID=UPI000198447D
          Length = 883

 Score =  120 bits (300), Expect = 6e-26
 Identities = 56/67 (83%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RDMK KEDL+TVALGTS+INYLDPRI+VAWC+R EVPIEKIFN+SLLAKF WAMD
Sbjct: 817  IEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMD 876

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 877  VDPSFRF 883

[9][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
          Length = 877

 Score =  120 bits (300), Expect = 6e-26
 Identities = 56/67 (83%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+  MK KEDL+TVALGTS+INYLDPRITVAWC+RHEVPI+KIFN+SLLAKFTWAMD
Sbjct: 811  IEKMEMAMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAMD 870

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 871  VDPQFRF 877

[10][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
           Tax=Vitis vinifera RepID=A7PX10_VITVI
          Length = 789

 Score =  120 bits (300), Expect = 6e-26
 Identities = 56/67 (83%), Positives = 62/67 (92%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDMK KEDL+TVALGTS+INYLDPRI+VAWC+R EVPIEKIFN+SLLAKF WAMD
Sbjct: 723 IEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMD 782

Query: 238 VXPDFRF 218
           V P FRF
Sbjct: 783 VDPSFRF 789

[11][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
          Length = 927

 Score =  119 bits (299), Expect = 8e-26
 Identities = 55/67 (82%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD + KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKF W+MD
Sbjct: 861  IEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMD 920

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 921  VDPSFRF 927

[12][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
          Length = 904

 Score =  119 bits (297), Expect = 1e-25
 Identities = 55/67 (82%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+ D + KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKF WAMD
Sbjct: 838  IEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMD 897

Query: 238  VXPDFRF 218
            V P+FRF
Sbjct: 898  VDPEFRF 904

[13][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
            RepID=C5YGY1_SORBI
          Length = 921

 Score =  119 bits (297), Expect = 1e-25
 Identities = 55/67 (82%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I+KM+ D K KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SL+AKF WAMD
Sbjct: 855  IDKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFGWAMD 914

Query: 238  VXPDFRF 218
            V PDFRF
Sbjct: 915  VDPDFRF 921

[14][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
           RepID=B7ZWU7_MAIZE
          Length = 574

 Score =  119 bits (297), Expect = 1e-25
 Identities = 55/67 (82%), Positives = 62/67 (92%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+ D + KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIFN+SLLAKF WAMD
Sbjct: 508 IEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMD 567

Query: 238 VXPDFRF 218
           V P+FRF
Sbjct: 568 VDPEFRF 574

[15][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
           thaliana RepID=Q8RX06_ARATH
          Length = 514

 Score =  117 bits (294), Expect = 3e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDM  KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIF +SLL KF WAMD
Sbjct: 445 IEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMD 504

Query: 238 VXPDFRF 218
           V P++RF
Sbjct: 505 VEPEYRF 511

[16][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
           RepID=Q56XA9_ARATH
          Length = 396

 Score =  117 bits (294), Expect = 3e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDM  KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIF +SLL KF WAMD
Sbjct: 327 IEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMD 386

Query: 238 VXPDFRF 218
           V P++RF
Sbjct: 387 VEPEYRF 393

[17][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
           RepID=Q56X27_ARATH
          Length = 270

 Score =  117 bits (294), Expect = 3e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDM  KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIF +SLL KF WAMD
Sbjct: 201 IEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMD 260

Query: 238 VXPDFRF 218
           V P++RF
Sbjct: 261 VEPEYRF 267

[18][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
          Length = 916

 Score =  117 bits (294), Expect = 3e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RDM  KEDL+TVALGTS+INYLDPRITVAWC+RHEVPIEKIF +SLL KF WAMD
Sbjct: 847  IEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMD 906

Query: 238  VXPDFRF 218
            V P++RF
Sbjct: 907  VEPEYRF 913

[19][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
          Length = 909

 Score =  117 bits (293), Expect = 4e-25
 Identities = 54/67 (80%), Positives = 62/67 (92%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD + KEDL+TVALGTS+INYLDPRITVAWC+R+EVPIEK+FN+SLLAKF WAMD
Sbjct: 843  IEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMD 902

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 903  VEPSFRF 909

[20][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
           n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
          Length = 857

 Score =  117 bits (293), Expect = 4e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RD   KEDL+TVALGTS+INYLDPRI+VAWC+R EVPIEK+FN+SLLAKF WAMD
Sbjct: 791 IEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMD 850

Query: 238 VXPDFRF 218
           V PDFRF
Sbjct: 851 VPPDFRF 857

[21][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
            RepID=A5BM51_VITVI
          Length = 1449

 Score =  117 bits (293), Expect = 4e-25
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD   KEDL+TVALGTS+INYLDPRI+VAWC+R EVPIEK+FN+SLLAKF WAMD
Sbjct: 1383 IEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMD 1442

Query: 238  VXPDFRF 218
            V PDFRF
Sbjct: 1443 VPPDFRF 1449

[22][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
           RepID=A9T3W2_PHYPA
          Length = 632

 Score =  116 bits (291), Expect = 7e-25
 Identities = 52/67 (77%), Positives = 63/67 (94%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+KM+ DM+ K+DL+TVALGTS+INY+DPRITVAWC+RHEVPIEKIFN+SLL+KF WAM+
Sbjct: 566 IDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKIFNKSLLSKFAWAME 625

Query: 238 VXPDFRF 218
           V PDFRF
Sbjct: 626 VEPDFRF 632

[23][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
           RepID=A9T368_PHYPA
          Length = 502

 Score =  116 bits (291), Expect = 7e-25
 Identities = 52/67 (77%), Positives = 63/67 (94%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+KM+ DM+ K+DL+TVALGTS+INY+DPRITVAWC+RHEVPIEKIFN+SLL+KF WAM+
Sbjct: 436 IDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKIFNKSLLSKFAWAME 495

Query: 238 VXPDFRF 218
           V PDFRF
Sbjct: 496 VEPDFRF 502

[24][TOP]
>UniRef100_B3H4K2 Uncharacterized protein At4g26701.1 n=1 Tax=Arabidopsis thaliana
           RepID=B3H4K2_ARATH
          Length = 69

 Score =  116 bits (290), Expect = 9e-25
 Identities = 53/67 (79%), Positives = 60/67 (89%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RDM+ KEDL+TVALGTS+INY+DPRITVAWC+RHE PIEKIFN+SLL KF WAMD
Sbjct: 3   IEKMERDMQTKEDLKTVALGTSKINYMDPRITVAWCKRHEAPIEKIFNKSLLEKFAWAMD 62

Query: 238 VXPDFRF 218
           V P F F
Sbjct: 63  VEPHFTF 69

[25][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
          Length = 926

 Score =  115 bits (287), Expect = 2e-24
 Identities = 53/67 (79%), Positives = 60/67 (89%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD K KEDL+ VAL TS+I+YLDPRITVAWC+RHEVPIEKIFN+SLLAKF W+MD
Sbjct: 860  IEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMD 919

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 920  VDPSFRF 926

[26][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
          Length = 790

 Score =  114 bits (286), Expect = 3e-24
 Identities = 54/67 (80%), Positives = 61/67 (91%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IEKM+RD + KEDL+TVALGTS+INYLDPRITVAWC+RH+VPIEKIFN+SLLAKF WAMD
Sbjct: 724 IEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMD 783

Query: 238 VXPDFRF 218
           V   FRF
Sbjct: 784 VVLIFRF 790

[27][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
          Length = 894

 Score =  114 bits (285), Expect = 3e-24
 Identities = 51/67 (76%), Positives = 61/67 (91%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD + KE L+T+ALGTS+I+YLDPRITVAWC+RHEVPIEK+FN+SLLAKF W+MD
Sbjct: 828  IEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMD 887

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 888  VDPSFRF 894

[28][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
          Length = 926

 Score =  112 bits (279), Expect = 2e-23
 Identities = 52/67 (77%), Positives = 59/67 (88%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            IEKM+RD K KEDL+ VAL TS+I+YLDPRITVAWC+R EVPIEK+FN+SLLAKF WAMD
Sbjct: 860  IEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMD 919

Query: 238  VXPDFRF 218
            V P FRF
Sbjct: 920  VDPSFRF 926

[29][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8IDM1_CHLRE
          Length = 586

 Score =  108 bits (270), Expect = 2e-22
 Identities = 50/67 (74%), Positives = 59/67 (88%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I K++   + KEDL+TVALGTS+INY+DPRITVAWC+R+EVPIEKIFN+SLLAKF WAMD
Sbjct: 520 IAKVELQARSKEDLKTVALGTSKINYMDPRITVAWCKRNEVPIEKIFNKSLLAKFNWAMD 579

Query: 238 VXPDFRF 218
           V P FRF
Sbjct: 580 VDPTFRF 586

[30][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
          Length = 892

 Score = 94.0 bits (232), Expect(2) = 1e-19
 Identities = 44/52 (84%), Positives = 49/52 (94%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLL 263
           IEKMQRDMK K DL+TVALGTS+INYLDPRITVAWC+RHEVPIEK+F +SLL
Sbjct: 821 IEKMQRDMKTKVDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKLFTKSLL 872

 Score = 26.2 bits (56), Expect(2) = 1e-19
 Identities = 14/26 (53%), Positives = 16/26 (61%)
 Frame = -1

Query: 288 KRFSTSLCWPSSLGLWMWXLTSDSEI 211
           K F+ SL   + LG WMW   SDSEI
Sbjct: 865 KLFTKSLL-QNLLGQWMWTQISDSEI 889

[31][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B5Y3I3_PHATR
          Length = 594

 Score = 94.4 bits (233), Expect = 4e-18
 Identities = 42/67 (62%), Positives = 56/67 (83%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I KM+ D+K K+D + V+LGTS+INY+DPRI+VAWC+R+EVPIEKIF+++L  KF WAM 
Sbjct: 520 ISKMEMDLKHKDDNKEVSLGTSKINYMDPRISVAWCKRNEVPIEKIFSKTLRDKFNWAMA 579

Query: 238 VXPDFRF 218
           V PD+ F
Sbjct: 580 VVPDWEF 586

[32][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MGX0_9CHLO
          Length = 685

 Score = 93.6 bits (231), Expect = 6e-18
 Identities = 40/67 (59%), Positives = 55/67 (82%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K++  MK KEDL+TV+LGTS+INYLDPRIT+AWC+R+EVP   +F ++L+ KF W+M+
Sbjct: 619 LAKLELQMKMKEDLKTVSLGTSKINYLDPRITIAWCKRNEVPPPTVFTRALVEKFNWSME 678

Query: 238 VXPDFRF 218
           V PDF F
Sbjct: 679 VEPDFDF 685

[33][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
           RepID=B8CC91_THAPS
          Length = 536

 Score = 90.9 bits (224), Expect = 4e-17
 Identities = 39/67 (58%), Positives = 58/67 (86%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+KM+ ++K K+D + V+LGTS++NY+DPRI+VAWC+R+EVPIEKIF++++  KF WAM 
Sbjct: 462 IKKMELNIKHKDDNKEVSLGTSKLNYMDPRISVAWCKRNEVPIEKIFSKTMRDKFNWAMA 521

Query: 238 VXPDFRF 218
           V PD++F
Sbjct: 522 VTPDWQF 528

[34][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
            Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
          Length = 886

 Score = 89.7 bits (221), Expect = 9e-17
 Identities = 40/67 (59%), Positives = 55/67 (82%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            +E ++  MK ++D +T+ALGTS+INY+DPRITVA+C++ E+PIEKIFN+SL  KF WAM 
Sbjct: 820  VELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQFEIPIEKIFNRSLRLKFPWAMF 879

Query: 238  VXPDFRF 218
            V  +FRF
Sbjct: 880  VTKNFRF 886

[35][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
            RepID=B3L6G4_PLAKH
          Length = 924

 Score = 89.7 bits (221), Expect = 9e-17
 Identities = 40/67 (59%), Positives = 55/67 (82%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            +E+++  MK ++D +T+ALGTS+INY+DPRITVA+C+R E+PIEKIFN+SL  KF WAM 
Sbjct: 858  VEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRFEIPIEKIFNRSLRLKFPWAMF 917

Query: 238  VXPDFRF 218
            V  +F F
Sbjct: 918  VTKNFTF 924

[36][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax RepID=A5KB33_PLAVI
          Length = 931

 Score = 89.7 bits (221), Expect = 9e-17
 Identities = 40/67 (59%), Positives = 55/67 (82%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            +E+++  MK ++D +T+ALGTS+INY+DPRITVA+C+R E+PIEKIFN+SL  KF WAM 
Sbjct: 865  VEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRFEIPIEKIFNRSLRLKFPWAMF 924

Query: 238  VXPDFRF 218
            V  +F F
Sbjct: 925  VTKNFTF 931

[37][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
           RepID=Q00XV7_OSTTA
          Length = 783

 Score = 87.4 bits (215), Expect = 4e-16
 Identities = 38/65 (58%), Positives = 52/65 (80%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           K+   M+ KE+L+TV+LGTS+INYLDPRIT++WC+RHEVP   +F ++L+ KF WAMD  
Sbjct: 695 KLAIQMEMKEELKTVSLGTSKINYLDPRITLSWCKRHEVPPPTVFTKALIDKFHWAMDCD 754

Query: 232 PDFRF 218
            DF+F
Sbjct: 755 MDFKF 759

[38][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
           RepID=C1FD86_9CHLO
          Length = 635

 Score = 85.9 bits (211), Expect = 1e-15
 Identities = 34/67 (50%), Positives = 54/67 (80%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K++  MK K++L++V+LGTS+INY+DPRIT+AWC+ ++VP   ++ ++L+ KF WAM+
Sbjct: 569 LSKLELQMKMKDELKSVSLGTSKINYMDPRITIAWCKHNDVPPPTVYTKALVEKFNWAME 628

Query: 238 VXPDFRF 218
           V PDF F
Sbjct: 629 VEPDFDF 635

[39][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
          Length = 701

 Score = 85.5 bits (210), Expect = 2e-15
 Identities = 40/60 (66%), Positives = 50/60 (83%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVXPDFRF 218
           M+ K+D +TVALGTS+INY+DPRITVA+C+R+EVPIEKIFN+SL  KF WAM    D+ F
Sbjct: 642 MRIKDDNKTVALGTSKINYMDPRITVAFCKRYEVPIEKIFNKSLRTKFPWAMYAGADYIF 701

[40][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
            RepID=Q4UDP8_THEAN
          Length = 999

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 41/71 (57%), Positives = 55/71 (77%), Gaps = 4/71 (5%)
 Frame = -3

Query: 418  IEKMQRD----MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFT 251
            ++K Q+D    M  K+  +TVALGTS+INY+DPRITVA+C+++E+PIEK+FN+SL  KF 
Sbjct: 929  LKKKQKDHNIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKVFNKSLRMKFP 988

Query: 250  WAMDVXPDFRF 218
            WAM V  DF F
Sbjct: 989  WAMCVRSDFTF 999

[41][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
            RepID=Q4N5U3_THEPA
          Length = 1003

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 41/71 (57%), Positives = 55/71 (77%), Gaps = 4/71 (5%)
 Frame = -3

Query: 418  IEKMQRD----MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFT 251
            ++K Q+D    M  K+  +TVALGTS+INY+DPRITVA+C+++E+PIEK+FN+SL  KF 
Sbjct: 933  LKKKQKDHAIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKVFNKSLRMKFP 992

Query: 250  WAMDVXPDFRF 218
            WAM V  DF F
Sbjct: 993  WAMYVRSDFTF 1003

[42][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
          Length = 839

 Score = 85.1 bits (209), Expect = 2e-15
 Identities = 37/67 (55%), Positives = 52/67 (77%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +E +   MK ++D +T+ALGTS+INY+DPRITVA+C++ E+PIEK+FN+SL  KF WAM 
Sbjct: 773 VELLNNQMKVRDDNKTIALGTSKINYMDPRITVAFCKKFEIPIEKVFNRSLRLKFPWAMF 832

Query: 238 VXPDFRF 218
              +F F
Sbjct: 833 ATKNFTF 839

[43][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
           RepID=A4S5R8_OSTLU
          Length = 491

 Score = 84.3 bits (207), Expect = 4e-15
 Identities = 37/65 (56%), Positives = 50/65 (76%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           K+   M  KE+L+TV+LGTS+INYLDPRIT++WC+RHEVP   +F ++L+ KF WAMD  
Sbjct: 415 KLAIQMNMKEELKTVSLGTSKINYLDPRITLSWCKRHEVPPNVVFTKALIDKFHWAMDCE 474

Query: 232 PDFRF 218
            +F F
Sbjct: 475 MEFSF 479

[44][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
           RepID=UPI000056C59B
          Length = 196

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 36/68 (52%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K+Q     +E+ + +ALGTS++NYLDPRITVAWC++H+VPIEKIFN++   KF WA+D
Sbjct: 129 LKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKIFNKTHREKFAWAID 188

Query: 238 VXPD-FRF 218
           +  + F+F
Sbjct: 189 MTDESFQF 196

[45][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
           RepID=Q6T721_DANRE
          Length = 600

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 36/68 (52%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K+Q     +E+ + +ALGTS++NYLDPRITVAWC++H+VPIEKIFN++   KF WA+D
Sbjct: 533 LKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKIFNKTHREKFAWAID 592

Query: 238 VXPD-FRF 218
           +  + F+F
Sbjct: 593 MTDESFQF 600

[46][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
            RepID=B9Q6S5_TOXGO
          Length = 953

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = -3

Query: 397  MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVXPDFRF 218
            +K K+D +TVALGTS+INY+DPRITVA+C+++EVPIEK+FN+SL  KF WAM     F F
Sbjct: 894  IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953

[47][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
            RepID=B9PWF4_TOXGO
          Length = 953

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = -3

Query: 397  MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVXPDFRF 218
            +K K+D +TVALGTS+INY+DPRITVA+C+++EVPIEK+FN+SL  KF WAM     F F
Sbjct: 894  IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953

[48][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
            RepID=B6KM03_TOXGO
          Length = 953

 Score = 82.4 bits (202), Expect = 1e-14
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = -3

Query: 397  MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVXPDFRF 218
            +K K+D +TVALGTS+INY+DPRITVA+C+++EVPIEK+FN+SL  KF WAM     F F
Sbjct: 894  IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953

[49][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
            RepID=UPI0000DB758E
          Length = 973

 Score = 80.9 bits (198), Expect = 4e-14
 Identities = 36/68 (52%), Positives = 52/68 (76%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            + K++     KE+ + +ALGTS++NYLDPRITVAWC++H VPIEKI+N++   KF WA+D
Sbjct: 906  LTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAID 965

Query: 238  V-XPDFRF 218
            +  PD+ F
Sbjct: 966  MAGPDYVF 973

[50][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
          Length = 893

 Score = 79.7 bits (195), Expect = 9e-14
 Identities = 38/67 (56%), Positives = 53/67 (79%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I+K +     K++L+TVALGTS+INYLDPRITVAWC++++VP++KIF +SL  KF W+ D
Sbjct: 828  IKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPVDKIFTKSLRDKFPWS-D 886

Query: 238  VXPDFRF 218
            V  D+ F
Sbjct: 887  VGTDYIF 893

[51][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
           parvum Iowa II RepID=Q5CY81_CRYPV
          Length = 653

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 36/67 (53%), Positives = 51/67 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I  +   +K K+D +TVAL TS+INY+DPRI+VA+C+++++PI+KIFN+SL  KF WAM 
Sbjct: 587 ISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKIFNRSLRTKFPWAMY 646

Query: 238 VXPDFRF 218
              DF F
Sbjct: 647 TRSDFSF 653

[52][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
           RepID=Q5CN58_CRYHO
          Length = 641

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 36/67 (53%), Positives = 51/67 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I  +   +K K+D +TVAL TS+INY+DPRI+VA+C+++++PI+KIFN+SL  KF WAM 
Sbjct: 575 ISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKIFNRSLRTKFPWAMY 634

Query: 238 VXPDFRF 218
              DF F
Sbjct: 635 TRSDFSF 641

[53][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
            RepID=UPI000186E5D8
          Length = 961

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 35/66 (53%), Positives = 52/66 (78%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412  KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
            K++     KE+ +T+ALGTS++NYLDPRI+VAWC+++ VPIEKI+N++   KF WA+D+ 
Sbjct: 896  KLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMA 955

Query: 235  XPDFRF 218
             PD+ F
Sbjct: 956  GPDYVF 961

[54][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
            vitripennis RepID=UPI00015B4D8F
          Length = 1019

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 34/66 (51%), Positives = 52/66 (78%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412  KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
            K++     +E+ + +ALGTS++NYLDPRI+VAWC++H+VPIEKI+N++   KF WA+D+ 
Sbjct: 954  KLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHDVPIEKIYNKTQRDKFRWAIDMA 1013

Query: 235  XPDFRF 218
             PD+ F
Sbjct: 1014 GPDYVF 1019

[55][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
           RepID=Q8IR39_DROME
          Length = 581

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H+VPIEKIFN++   KF WA+ 
Sbjct: 514 LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVH 573

Query: 238 VXPD-FRF 218
           +  + +RF
Sbjct: 574 MADENYRF 581

[56][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
            RepID=Q494M1_DROME
          Length = 974

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H+VPIEKIFN++   KF WA+ 
Sbjct: 907  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVH 966

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 967  MADENYRF 974

[57][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
          Length = 581

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H+VPIEKIFN++   KF WA+ 
Sbjct: 514 LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVH 573

Query: 238 VXPD-FRF 218
           +  + +RF
Sbjct: 574 MADENYRF 581

[58][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
           RepID=B6ABX7_9CRYT
          Length = 660

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/67 (49%), Positives = 52/67 (77%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +  ++  +K K+D +TV+L TS++NY+DPRI+VA+C+++E+PI+K+FN+SL  KF WAM 
Sbjct: 594 LSNLELKIKIKDDNKTVSLNTSKLNYMDPRISVAFCKKYELPIDKVFNRSLRTKFPWAMY 653

Query: 238 VXPDFRF 218
              DF F
Sbjct: 654 TRSDFSF 660

[59][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
          Length = 969

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H+VPIEKIFN++   KF WA+ 
Sbjct: 902  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVH 961

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 962  MADENYRF 969

[60][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
          Length = 972

 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H+VPIEKIFN++   KF WA+ 
Sbjct: 905  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVH 964

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 965  MADENYRF 972

[61][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8N6Y9_COPC7
          Length = 863

 Score = 77.8 bits (190), Expect = 3e-13
 Identities = 36/67 (53%), Positives = 51/67 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+  +  M  +++ + VALGTS+INYLDPRITVAW   ++VPIEK+F+++LL KF WAM 
Sbjct: 797 IKTFKLQMIDRDEGKEVALGTSKINYLDPRITVAWASANKVPIEKMFSKTLLEKFPWAMG 856

Query: 238 VXPDFRF 218
           V  D++F
Sbjct: 857 VDDDWKF 863

[62][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
          Length = 990

 Score = 77.0 bits (188), Expect = 6e-13
 Identities = 33/68 (48%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++H VPIEKIFN++   KF WA+ 
Sbjct: 923  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIFNKTQRTKFLWAVH 982

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 983  MADENYRF 990

[63][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
           Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
          Length = 713

 Score = 76.6 bits (187), Expect = 8e-13
 Identities = 33/67 (49%), Positives = 49/67 (73%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I++ Q   + KE  + +ALGTS+ NY DPRI+V WC++ EVP+EK+F ++L+AKF WAMD
Sbjct: 647 IDEEQNKKQSKEKNKEIALGTSKTNYNDPRISVVWCKKWEVPVEKVFPKTLIAKFVWAMD 706

Query: 238 VXPDFRF 218
              ++ F
Sbjct: 707 TDLEWSF 713

[64][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
            RepID=B0WA62_CULQU
          Length = 962

 Score = 76.3 bits (186), Expect = 1e-12
 Identities = 31/61 (50%), Positives = 50/61 (81%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++ +VPIEKIFN++   KF WA+D
Sbjct: 895  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFDVPIEKIFNKTQRDKFRWAID 954

Query: 238  V 236
            +
Sbjct: 955  M 955

[65][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
            Tax=Tribolium castaneum RepID=UPI00017582B6
          Length = 936

 Score = 75.9 bits (185), Expect = 1e-12
 Identities = 33/68 (48%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            + K++     +++ +T+ALGTS++NYLDPRI+VAWC+++ VPIEKI+N++   KF WA+D
Sbjct: 869  LTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKFRWAID 928

Query: 238  V-XPDFRF 218
            +  PD+ F
Sbjct: 929  MAGPDYVF 936

[66][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
          Length = 580

 Score = 75.9 bits (185), Expect = 1e-12
 Identities = 32/68 (47%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++++VPIEKIFN++   KF WA+ 
Sbjct: 513 LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIFNKTQRTKFLWAVH 572

Query: 238 VXPD-FRF 218
           +  + +RF
Sbjct: 573 MADENYRF 580

[67][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
          Length = 1045

 Score = 75.9 bits (185), Expect = 1e-12
 Identities = 33/68 (48%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRITVAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 978  LKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKKYGVPIEKIFNKTHRTKFLWAIH 1037

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 1038 MADENYRF 1045

[68][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
          Length = 1043

 Score = 75.9 bits (185), Expect = 1e-12
 Identities = 33/68 (48%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRITVAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 976  LKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKKYGVPIEKIFNKTHRTKFLWAIH 1035

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 1036 MADENYRF 1043

[69][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
          Length = 970

 Score = 75.9 bits (185), Expect = 1e-12
 Identities = 32/68 (47%), Positives = 54/68 (79%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++++VPIEKIFN++   KF WA+ 
Sbjct: 903  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIFNKTQRTKFLWAVH 962

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 963  MADENYRF 970

[70][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
           guttata RepID=UPI000194BDF0
          Length = 662

 Score = 75.5 bits (184), Expect = 2e-12
 Identities = 34/68 (50%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + KM      KE+ + +ALGTS++NYLDPRITVAWC++  +PIE+I+N++   KF WA+D
Sbjct: 595 LAKMNIQATDKEENKQIALGTSKLNYLDPRITVAWCKKFGIPIERIYNKTQREKFAWAID 654

Query: 238 V-XPDFRF 218
           +   DF F
Sbjct: 655 MAGEDFEF 662

[71][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
           RepID=UPI0001792028
          Length = 1011

 Score = 75.5 bits (184), Expect = 2e-12
 Identities = 32/61 (52%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K++     KE+ +T+ALGTS++NYLDPRI+VAWC++  VPIEKI+N++   KF WA+D
Sbjct: 680 LTKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKFNVPIEKIYNKTQRDKFRWAID 739

Query: 238 V 236
           +
Sbjct: 740 M 740

[72][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
          Length = 966

 Score = 75.5 bits (184), Expect = 2e-12
 Identities = 32/61 (52%), Positives = 48/61 (78%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            + K++     K++ +T+ALGTS++NYLDPRI+VAWC++  VPIEKIFN++   KF WA+D
Sbjct: 899  LNKLELQETDKDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAID 958

Query: 238  V 236
            +
Sbjct: 959  M 959

[73][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
          Length = 502

 Score = 75.5 bits (184), Expect = 2e-12
 Identities = 35/66 (53%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     KE+ + +ALGTS++NYLDPRITVAWC++ EVPIEK +N++   KF WA+D+ 
Sbjct: 437 KLEVTATDKEENKEIALGTSKLNYLDPRITVAWCKKFEVPIEKAYNKTQREKFAWAIDMA 496

Query: 235 XPDFRF 218
             DF F
Sbjct: 497 GEDFVF 502

[74][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
           RepID=UPI0000ECD01B
          Length = 593

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 34/68 (50%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K+      KE+ + +ALGTS++NYLDPRI++AWC++  VPIEKIFN++   KF WA+D
Sbjct: 526 LAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKIFNKTQREKFAWAID 585

Query: 238 V-XPDFRF 218
           +   DF F
Sbjct: 586 MTDEDFEF 593

[75][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
           RepID=Q6T722_CHICK
          Length = 593

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 34/68 (50%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K+      KE+ + +ALGTS++NYLDPRI++AWC++  VPIEKIFN++   KF WA+D
Sbjct: 526 LAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKIFNKTQREKFAWAID 585

Query: 238 V-XPDFRF 218
           +   DF F
Sbjct: 586 MTDEDFEF 593

[76][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
          Length = 969

 Score = 74.7 bits (182), Expect = 3e-12
 Identities = 31/61 (50%), Positives = 49/61 (80%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++  VPIEKIFN++   KF WA+D
Sbjct: 902  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAID 961

Query: 238  V 236
            +
Sbjct: 962  M 962

[77][TOP]
>UniRef100_C7E3P0 Topoisomerase family protein (Fragment) n=1 Tax=Caenorhabditis
           brenneri RepID=C7E3P0_CAEBE
          Length = 159

 Score = 74.7 bits (182), Expect = 3e-12
 Identities = 30/61 (49%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     K++ + +ALGTS++NYLDPRITVAWC+ H+VP+EK+F ++   KF WA+D
Sbjct: 89  LKKLKIARTDKDENKQIALGTSKLNYLDPRITVAWCKEHDVPLEKVFTKTHREKFRWAID 148

Query: 238 V 236
           +
Sbjct: 149 M 149

[78][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B1DB6
          Length = 770

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 705 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 764

Query: 235 XPDFRF 218
             DF F
Sbjct: 765 EKDFEF 770

[79][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5FAF
          Length = 573

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 508 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 567

Query: 235 XPDFRF 218
             DF F
Sbjct: 568 EKDFEF 573

[80][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5F98
          Length = 790

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 725 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 784

Query: 235 XPDFRF 218
             DF F
Sbjct: 785 EKDFEF 790

[81][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5F96
          Length = 767

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 702 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 761

Query: 235 XPDFRF 218
             DF F
Sbjct: 762 EKDFEF 767

[82][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
          Length = 767

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 702 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 761

Query: 235 XPDFRF 218
             DF F
Sbjct: 762 EKDFEF 767

[83][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
          Length = 783

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 718 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 777

Query: 235 XPDFRF 218
             DF F
Sbjct: 778 EKDFEF 783

[84][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
            RepID=B5DMS2_DROPS
          Length = 1054

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 32/68 (47%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 987  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNGVPIEKIFNKTQRTKFLWAVH 1046

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 1047 MADENYRF 1054

[85][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
          Length = 1042

 Score = 74.3 bits (181), Expect = 4e-12
 Identities = 32/68 (47%), Positives = 53/68 (77%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+ALGTS++NYLDPRI+VAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 975  LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNGVPIEKIFNKTQRTKFLWAVH 1034

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 1035 MADENYRF 1042

[86][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
           Tax=Ornithorhynchus anatinus RepID=UPI0001555600
          Length = 689

 Score = 73.9 bits (180), Expect = 5e-12
 Identities = 34/66 (51%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K+      KE+ + +ALGTS++NYLDPRI+VAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 624 KLSVQATDKEENKQIALGTSKLNYLDPRISVAWCKKFGVPIEKIYNKTQREKFAWAIDMA 683

Query: 235 XPDFRF 218
             DF F
Sbjct: 684 DEDFEF 689

[87][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
           scrofa RepID=UPI00017EFDA4
          Length = 748

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 683 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 742

Query: 235 XPDFRF 218
             D+ F
Sbjct: 743 DEDYEF 748

[88][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
           caballus RepID=UPI0001797824
          Length = 765

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 700 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 759

Query: 235 XPDFRF 218
             D+ F
Sbjct: 760 DEDYEF 765

[89][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
           RepID=UPI00006D45A8
          Length = 767

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 702 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 761

Query: 235 XPDFRF 218
             D+ F
Sbjct: 762 DEDYEF 767

[90][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
            familiaris RepID=UPI00005A45B7
          Length = 1004

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412  KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
            K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 939  KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 998

Query: 235  XPDFRF 218
              D+ F
Sbjct: 999  DEDYEF 1004

[91][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B3173
          Length = 622

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 30/59 (50%), Positives = 47/59 (79%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++ EVP++KI+N+S   KF WA+D+
Sbjct: 557 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKIYNKSQRDKFAWAIDM 615

[92][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
           norvegicus RepID=UPI0001B7BF13
          Length = 760

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 695 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 754

Query: 235 XPDFRF 218
             D+ F
Sbjct: 755 DEDYEF 760

[93][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
          Length = 758

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 693 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 752

Query: 235 XPDFRF 218
             D+ F
Sbjct: 753 DEDYEF 758

[94][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
          Length = 752

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 687 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 746

Query: 235 XPDFRF 218
             D+ F
Sbjct: 747 DEDYEF 752

[95][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
           RepID=UPI00006154BF
          Length = 769

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 704 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 763

Query: 235 XPDFRF 218
             D+ F
Sbjct: 764 DEDYEF 769

[96][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
          Length = 622

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 30/59 (50%), Positives = 47/59 (79%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++ EVP++KI+N+S   KF WA+D+
Sbjct: 557 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKIYNKSQRDKFAWAIDM 615

[97][TOP]
>UniRef100_Q6LBJ1 Topoisomerase I (Fragment) n=1 Tax=Mus musculus RepID=Q6LBJ1_MOUSE
          Length = 115

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 50  KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 109

Query: 235 XPDFRF 218
             D+ F
Sbjct: 110 DEDYEF 115

[98][TOP]
>UniRef100_Q3TSR2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
           RepID=Q3TSR2_MOUSE
          Length = 144

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 79  KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 138

Query: 235 XPDFRF 218
             D+ F
Sbjct: 139 DEDYEF 144

[99][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
          Length = 560

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 495 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 554

Query: 235 XPDFRF 218
             D+ F
Sbjct: 555 DEDYEF 560

[100][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
           RepID=A8Q2Z1_BRUMA
          Length = 751

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 30/61 (49%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K++     K++ + +AL TS++NYLDPRI+VAWC++++VPIEKIFN++   KF WA+D
Sbjct: 684 LRKLKIQRTDKDENKQIALSTSKLNYLDPRISVAWCKKYQVPIEKIFNKTQREKFRWAID 743

Query: 238 V 236
           +
Sbjct: 744 M 744

[101][TOP]
>UniRef100_Q9BVT2 Putative uncharacterized protein (Fragment) n=1 Tax=Homo sapiens
           RepID=Q9BVT2_HUMAN
          Length = 176

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 111 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 170

Query: 235 XPDFRF 218
             D+ F
Sbjct: 171 DEDYEF 176

[102][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
          Length = 765

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 700 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 759

Query: 235 XPDFRF 218
             D+ F
Sbjct: 760 DEDYEF 765

[103][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
          Length = 785

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/67 (49%), Positives = 51/67 (76%), Gaps = 7/67 (10%)
 Frame = -3

Query: 418 IEKMQR-------DMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+++        +K KED  TVALGTS+INY+DPR++VA+C++ +VPIEK+F ++L  
Sbjct: 711 VEKLEKRITNCSLQLKDKEDNSTVALGTSKINYIDPRLSVAFCKKFDVPIEKVFTKTLRD 770

Query: 259 KFTWAMD 239
           KF WA++
Sbjct: 771 KFRWAIE 777

[104][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
          Length = 767

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 702 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 761

Query: 235 XPDFRF 218
             D+ F
Sbjct: 762 DEDYEF 767

[105][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
          Length = 767

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 702 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 761

Query: 235 XPDFRF 218
             D+ F
Sbjct: 762 DEDYEF 767

[106][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
          Length = 765

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 700 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 759

Query: 235 XPDFRF 218
             D+ F
Sbjct: 760 DEDYEF 765

[107][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
          Length = 767

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 702 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMT 761

Query: 235 XPDFRF 218
             D+ F
Sbjct: 762 DEDYEF 767

[108][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
          Length = 767

 Score = 73.6 bits (179), Expect = 7e-12
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRITVAWC++  VPIEKI+N++   KF WA+D+ 
Sbjct: 702 KLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMA 761

Query: 235 XPDFRF 218
             D+ F
Sbjct: 762 DEDYEF 767

[109][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
           RepID=UPI00017968A4
          Length = 655

 Score = 73.2 bits (178), Expect = 9e-12
 Identities = 32/58 (55%), Positives = 46/58 (79%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV-XPDFRF 218
           KE+ + VALGTS++NYLDPRI+VAWC+R  VP+E+I+N++   +F WA+D+   DF F
Sbjct: 598 KEESKQVALGTSKLNYLDPRISVAWCKRFGVPVERIYNKTQRERFAWALDMAGEDFEF 655

[110][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
           RepID=O17966-2
          Length = 734

 Score = 73.2 bits (178), Expect = 9e-12
 Identities = 29/61 (47%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     K++ + +ALGTS++NY+DPRITVAWC++ EVP+EK+F ++   KF WA+D
Sbjct: 664 LKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAID 723

Query: 238 V 236
           +
Sbjct: 724 M 724

[111][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
          Length = 806

 Score = 73.2 bits (178), Expect = 9e-12
 Identities = 29/61 (47%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     K++ + +ALGTS++NY+DPRITVAWC++ EVP+EK+F ++   KF WA+D
Sbjct: 736 LKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAID 795

Query: 238 V 236
           +
Sbjct: 796 M 796

[112][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
           intestinalis RepID=UPI000180B1AE
          Length = 482

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 31/62 (50%), Positives = 46/62 (74%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           K++     KE+ + +ALGTS++NYLDPRITVAWC+++ VPIEK +N++   KF WA+ + 
Sbjct: 417 KLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKYSVPIEKCYNKTQRDKFAWAIAMV 476

Query: 232 PD 227
            D
Sbjct: 477 DD 478

[113][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
           RepID=UPI000176075D
          Length = 531

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           KM+     +E+ + +AL TS++NYLDPRI+VAWC+  EVP++KI+N++L  KF WA+D+ 
Sbjct: 466 KMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMT 525

Query: 232 P-DFRF 218
             DF F
Sbjct: 526 ELDFVF 531

[114][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
           RepID=UPI0001A2C88D
          Length = 609

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 33/66 (50%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           KM+     +E+ + +AL TS++NYLDPRI+VAWC+  EVP++KI+N++L  KF WA+D+ 
Sbjct: 544 KMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMT 603

Query: 232 P-DFRF 218
             DF F
Sbjct: 604 ELDFVF 609

[115][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
           RepID=TOP1_SCHPO
          Length = 814

 Score = 72.8 bits (177), Expect = 1e-11
 Identities = 31/67 (46%), Positives = 50/67 (74%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I  M+  M  K++ +T ALGTS+INY+DPR+T ++ +R +VPIEK+F++++  KF WA D
Sbjct: 748 INVMRTQMIDKDENKTTALGTSKINYIDPRLTYSFSKREDVPIEKLFSKTIRDKFNWAAD 807

Query: 238 VXPDFRF 218
             PD+++
Sbjct: 808 TPPDWKW 814

[116][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5C65
          Length = 755

 Score = 72.4 bits (176), Expect = 1e-11
 Identities = 29/62 (46%), Positives = 47/62 (75%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +P+EKI+N++   KF WA+D+ 
Sbjct: 690 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKIYNKTQREKFAWAIDMA 749

Query: 232 PD 227
            D
Sbjct: 750 ED 751

[117][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
          Length = 753

 Score = 72.4 bits (176), Expect = 1e-11
 Identities = 29/62 (46%), Positives = 47/62 (75%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +P+EKI+N++   KF WA+D+ 
Sbjct: 688 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKIYNKTQREKFAWAIDMA 747

Query: 232 PD 227
            D
Sbjct: 748 ED 749

[118][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
          Length = 758

 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 693 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMA 752

Query: 235 XPDFRF 218
             D+ F
Sbjct: 753 EKDYEF 758

[119][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
          Length = 997

 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 31/68 (45%), Positives = 52/68 (76%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+AL TS++NYLDPRI+VAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 930  LKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKKNGVPIEKIFNKTQRTKFLWAIH 989

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 990  MADENYRF 997

[120][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
          Length = 1063

 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 31/68 (45%), Positives = 52/68 (76%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++K++     +++ +T+AL TS++NYLDPRI+VAWC+++ VPIEKIFN++   KF WA+ 
Sbjct: 996  LKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKKNGVPIEKIFNKTQRTKFLWAIH 1055

Query: 238  VXPD-FRF 218
            +  + +RF
Sbjct: 1056 MADENYRF 1063

[121][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
           RepID=A8XXL4_CAEBR
          Length = 840

 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 28/61 (45%), Positives = 48/61 (78%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++K++     K++ + +ALGTS++NY+DPRITVAWC++ EVP+E++F ++   KF WA+D
Sbjct: 770 LKKLKIQRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLERVFTKTHREKFRWAID 829

Query: 238 V 236
           +
Sbjct: 830 M 830

[122][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
           RepID=UPI000194D872
          Length = 775

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 710 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 769

Query: 235 XPDFRF 218
             D+ F
Sbjct: 770 EEDYEF 775

[123][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
           anatinus RepID=UPI000155C8C4
          Length = 781

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 716 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 775

Query: 235 XPDFRF 218
             D+ F
Sbjct: 776 DEDYEF 781

[124][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
            RepID=UPI0000F2B3E5
          Length = 916

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412  KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
            K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 851  KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 910

Query: 235  XPDFRF 218
              D+ F
Sbjct: 911  DKDYEF 916

[125][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B27B1
          Length = 751

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 686 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 745

Query: 235 XPDFRF 218
             D+ F
Sbjct: 746 EKDYEF 751

[126][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
           RepID=UPI00017B27B0
          Length = 751

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 686 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 745

Query: 235 XPDFRF 218
             D+ F
Sbjct: 746 EKDYEF 751

[127][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5A49
          Length = 692

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 32/66 (48%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           KM+     +E+ + +ALGTS++NYLDPRI+VAWC+   +P++KI+N+S   KF WA+D+ 
Sbjct: 627 KMEIQATDREENKQIALGTSKLNYLDPRISVAWCKNMGLPVDKIYNKSQRDKFAWAIDMT 686

Query: 232 P-DFRF 218
             DF F
Sbjct: 687 EVDFEF 692

[128][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5A48
          Length = 632

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 32/66 (48%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDVX 233
           KM+     +E+ + +ALGTS++NYLDPRI+VAWC+   +P++KI+N+S   KF WA+D+ 
Sbjct: 567 KMEIQATDREENKQIALGTSKLNYLDPRISVAWCKNMGLPVDKIYNKSQRDKFAWAIDMT 626

Query: 232 P-DFRF 218
             DF F
Sbjct: 627 EVDFEF 632

[129][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
          Length = 806

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 741 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 800

Query: 235 XPDFRF 218
             D+ F
Sbjct: 801 EKDYEF 806

[130][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
          Length = 596

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 33/69 (47%), Positives = 52/69 (75%), Gaps = 3/69 (4%)
 Frame = -3

Query: 415 EKMQRDMK---PKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           EK Q+++K    KE+ + +ALGTS+ NY DPRI+VA+C+ H+VPIE++F+++L  KF WA
Sbjct: 528 EKYQKELKGLEKKEENKEIALGTSKTNYNDPRISVAFCKVHDVPIERVFSKTLRNKFIWA 587

Query: 244 MDVXPDFRF 218
           M    +++F
Sbjct: 588 MATDSNWKF 596

[131][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
           RepID=C5L755_9ALVE
          Length = 647

 Score = 71.2 bits (173), Expect = 3e-11
 Identities = 33/66 (50%), Positives = 48/66 (72%)
 Frame = -3

Query: 415 EKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV 236
           E+ +  +  KED +TV+L TS+INY+DPRI+VA+C+ H+ PIEKIF +++  KF WAM  
Sbjct: 582 ERTKIQIADKEDNKTVSLTTSKINYMDPRISVAFCKSHDCPIEKIFAKTIRNKFPWAMHS 641

Query: 235 XPDFRF 218
              +RF
Sbjct: 642 KSTWRF 647

[132][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
           RepID=C5DEP3_LACTC
          Length = 756

 Score = 71.2 bits (173), Expect = 3e-11
 Identities = 32/60 (53%), Positives = 45/60 (75%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IE     +K KED   VALGTS+INY+DPR++V +C+++ VPIEK+F +SL  KF WA++
Sbjct: 689 IETATIQLKDKEDNSQVALGTSKINYIDPRLSVVFCKKYGVPIEKVFTKSLRDKFKWAIE 748

[133][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
          Length = 732

 Score = 70.9 bits (172), Expect = 4e-11
 Identities = 29/53 (54%), Positives = 45/53 (84%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           MK KED  TVAL TS+I+Y+DPR++VA+C++++VP+EK+F ++L  KF WA++
Sbjct: 672 MKDKEDNSTVALSTSKISYIDPRLSVAFCKKYDVPLEKVFTKTLREKFKWAIE 724

[134][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
          Length = 440

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 32/68 (47%), Positives = 50/68 (73%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K++     KE+ + +ALGTS++NYLDPRI+VAW ++ +VPIEK++N++   KF WA+D
Sbjct: 373 LAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKVYNKTQRDKFRWAVD 432

Query: 238 V-XPDFRF 218
           +   DF F
Sbjct: 433 MAGADFVF 440

[135][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
            purpuratus RepID=UPI0000E471B7
          Length = 879

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 32/68 (47%), Positives = 50/68 (73%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            + K++     KE+ + +ALGTS++NYLDPRI+VAW ++ +VPIEK++N++   KF WA+D
Sbjct: 812  LAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKVYNKTQRDKFRWAVD 871

Query: 238  V-XPDFRF 218
            +   DF F
Sbjct: 872  MAGADFVF 879

[136][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
          Length = 1015

 Score = 70.5 bits (171), Expect = 6e-11
 Identities = 34/67 (50%), Positives = 46/67 (68%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I K       K++L++VAL TS+INY+DPRIT AW +R  + I K+F++SL  KF WAMD
Sbjct: 949  INKWNIKKTEKDELKSVALTTSKINYIDPRITAAWAKRVGLDIGKLFSKSLREKFPWAMD 1008

Query: 238  VXPDFRF 218
            V  D+ F
Sbjct: 1009 VEEDWEF 1015

[137][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
          Length = 881

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 35/68 (51%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M+   + KED + VALGTS+INY+DPR+TV + ++  VPIEK F++SL  KF WA+ 
Sbjct: 814  IETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIK 873

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 874  SVEQDWEF 881

[138][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
          Length = 745

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 32/68 (47%), Positives = 51/68 (75%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+     +K KE+   V+LGTS+INY+DPR++V +C++++VPIEKIF ++L  KF WA++
Sbjct: 678 IQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIE 737

Query: 238 -VXPDFRF 218
            V  ++RF
Sbjct: 738 SVDENWRF 745

[139][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
            RepID=B8MY66_ASPFN
          Length = 881

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 35/68 (51%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M+   + KED + VALGTS+INY+DPR+TV + ++  VPIEK F++SL  KF WA+ 
Sbjct: 814  IETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIK 873

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 874  SVEQDWEF 881

[140][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
           RepID=B3LJ50_YEAS1
          Length = 769

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 32/68 (47%), Positives = 51/68 (75%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+     +K KE+   V+LGTS+INY+DPR++V +C++++VPIEKIF ++L  KF WA++
Sbjct: 702 IQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIE 761

Query: 238 -VXPDFRF 218
            V  ++RF
Sbjct: 762 SVDENWRF 769

[141][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
           RepID=TOP1_YEAST
          Length = 769

 Score = 70.1 bits (170), Expect = 7e-11
 Identities = 32/68 (47%), Positives = 51/68 (75%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+     +K KE+   V+LGTS+INY+DPR++V +C++++VPIEKIF ++L  KF WA++
Sbjct: 702 IQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIE 761

Query: 238 -VXPDFRF 218
            V  ++RF
Sbjct: 762 SVDENWRF 769

[142][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
           rerio RepID=UPI0001760D92
          Length = 748

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 31/66 (46%), Positives = 49/66 (74%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +ALGTS++NYLDPRI+V+WC++  VPIEKI++++   KF WA+D+ 
Sbjct: 683 KLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKIYSKTQRDKFAWAIDMA 742

Query: 235 XPDFRF 218
             DF F
Sbjct: 743 DEDFEF 748

[143][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
          Length = 638

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 29/59 (49%), Positives = 47/59 (79%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           ++K++ +   +E+ + VAL TS++NY+DPRI+VAWC+++ VPIEKIFN++   KF WA+
Sbjct: 560 LKKLKLEETNREENKCVALTTSKLNYIDPRISVAWCKKNNVPIEKIFNKTQRTKFLWAI 618

[144][TOP]
>UniRef100_Q8TBP3 TOP1MT protein (Fragment) n=1 Tax=Homo sapiens RepID=Q8TBP3_HUMAN
          Length = 101

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 27  LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 86

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 87  RFAWALAMAGEDFEF 101

[145][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
           mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
           RepID=B7ZAR5_HUMAN
          Length = 503

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 429 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 488

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 489 RFAWALAMAGEDFEF 503

[146][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
           mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
           RepID=B7Z9E8_HUMAN
          Length = 503

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 429 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 488

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 489 RFAWALAMAGEDFEF 503

[147][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
           (EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
          Length = 503

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 429 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 488

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 489 RFAWALAMAGEDFEF 503

[148][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
          Length = 871

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 32/59 (54%), Positives = 45/59 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M+   + KED + VALGTS+INY+DPR+TV + ++ +VPIEK F++SL  KF WA+
Sbjct: 804 IENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWAI 862

[149][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
          Length = 881

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 30/61 (49%), Positives = 48/61 (78%), Gaps = 1/61 (1%)
 Frame = -3

Query: 397  MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA-MDVXPDFR 221
            ++ ++ L+ VALGTS+INY+DPR+TVAW ++ +VP+EK+F+++L  KF WA  +  PD+ 
Sbjct: 821  LQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKLFSKTLREKFPWAEAEAGPDWV 880

Query: 220  F 218
            F
Sbjct: 881  F 881

[150][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
           RepID=O59891_CRYNE
          Length = 844

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 30/61 (49%), Positives = 48/61 (78%), Gaps = 1/61 (1%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA-MDVXPDFR 221
           ++ ++ L+ VALGTS+INY+DPR+TVAW ++ +VP+EK+F+++L  KF WA  +  PD+ 
Sbjct: 784 LQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKLFSKTLREKFPWAEAEAGPDWV 843

Query: 220 F 218
           F
Sbjct: 844 F 844

[151][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
          Length = 871

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 32/59 (54%), Positives = 45/59 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M+   + KED + VALGTS+INY+DPR+TV + ++ +VPIEK F++SL  KF WA+
Sbjct: 804 IENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWAI 862

[152][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
           Tax=Emericella nidulans RepID=C8VUK1_EMENI
          Length = 871

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 32/59 (54%), Positives = 45/59 (76%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M+   + KED + VALGTS+INY+DPR+TV + ++ +VPIEK F++SL  KF WA+
Sbjct: 804 IENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWAI 862

[153][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
           DSM 70294 RepID=A7TJW1_VANPO
          Length = 799

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 32/68 (47%), Positives = 50/68 (73%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+     +K KE+   V+LGTS+INY+DPR++V +C++ ++PIEKIF +SL  KF WA++
Sbjct: 732 IQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKFDIPIEKIFTKSLREKFRWAIE 791

Query: 238 -VXPDFRF 218
            V  ++RF
Sbjct: 792 SVDENWRF 799

[154][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
           RepID=TOP1M_PANTR
          Length = 601

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 527 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 586

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 587 RFAWALAMAGEDFEF 601

[155][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
           RepID=TOP1M_HUMAN
          Length = 601

 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 8/75 (10%)
 Frame = -3

Query: 418 IEKMQRDMKP-------KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLA 260
           +EK+Q  +         KE+ + VALGTS++NYLDPRI++AWC+R  VP+EKI++++   
Sbjct: 527 LEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRE 586

Query: 259 KFTWAMDV-XPDFRF 218
           +F WA+ +   DF F
Sbjct: 587 RFAWALAMAGEDFEF 601

[156][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
          Length = 766

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 30/66 (45%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           K++     +E+ + +AL TS++NYLDPRI+VAWC++  +PIEKI+N++   KF WA+D+ 
Sbjct: 701 KLEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMA 760

Query: 235 XPDFRF 218
             D+ F
Sbjct: 761 EEDYEF 766

[157][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
           RepID=Q9D6H0_MOUSE
          Length = 295

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 30/58 (51%), Positives = 44/58 (75%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFRF 218
           KE+ + VALGT+++NYLDPRI++AWC+R  VP+EKI+N++   +F WA +    DF F
Sbjct: 238 KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 295

[158][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
          Length = 592

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 30/58 (51%), Positives = 44/58 (75%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFRF 218
           KE+ + VALGT+++NYLDPRI++AWC+R  VP+EKI+N++   +F WA +    DF F
Sbjct: 535 KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 592

[159][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
           adhaerens RepID=B3S6N7_TRIAD
          Length = 560

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 28/61 (45%), Positives = 46/61 (75%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           + K+      K + + VAL TS++NY+DPRI+VAWC+++EVP+EK+FN++   KF WA++
Sbjct: 493 LHKLNLTETDKVENKEVALSTSKLNYMDPRISVAWCKKNEVPVEKVFNKTQREKFKWAIE 552

Query: 238 V 236
           +
Sbjct: 553 M 553

[160][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6JVY3_SCHJY
          Length = 654

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 29/67 (43%), Positives = 47/67 (70%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+ M   +  K++ +T ALGTS+INY+DPR+T + C+R  +PIEK+F++++  KF WA D
Sbjct: 588 IKVMSNSIIDKDENKTTALGTSKINYIDPRLTFSLCKRENIPIEKLFSKTIRDKFNWAAD 647

Query: 238 VXPDFRF 218
              D+ +
Sbjct: 648 TPADWNW 654

[161][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
            RepID=B6H1W4_PENCW
          Length = 864

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 33/68 (48%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            +E M    + KED + VALGTS+INY+DPR+TV + ++++VPIEK F+++L  KF WA+ 
Sbjct: 797  VETMSVQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKYDVPIEKFFSKALREKFEWAIK 856

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 857  SVDEDWEF 864

[162][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
            n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
          Length = 884

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 34/68 (50%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M+   + KE+ + VALGTS+INY+DPR+TV + ++ +VPIEK F++SL  KF WA+ 
Sbjct: 817  IETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKSLREKFEWAIK 876

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 877  SVDEDWEF 884

[163][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
           RepID=TOP1M_RAT
          Length = 593

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 30/58 (51%), Positives = 44/58 (75%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFRF 218
           KE+ + VALGT+++NYLDPRI++AWC+R  VP+EKI+N++   +F WA +    DF F
Sbjct: 536 KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593

[164][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
           RepID=TOP1M_MOUSE
          Length = 593

 Score = 69.3 bits (168), Expect = 1e-10
 Identities = 30/58 (51%), Positives = 44/58 (75%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFRF 218
           KE+ + VALGT+++NYLDPRI++AWC+R  VP+EKI+N++   +F WA +    DF F
Sbjct: 536 KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593

[165][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
            RepID=Q0UUB0_PHANO
          Length = 887

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 34/68 (50%), Positives = 49/68 (72%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M+  M+ KE  + VALGTS+INY+DPR+TV + ++ +VPIEK F+++L  KF WA+ 
Sbjct: 820  IENMRIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLREKFDWAIK 879

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 880  SVDEDWEF 887

[166][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
            RepID=Q0CUT4_ASPTN
          Length = 872

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 34/68 (50%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M+   + KED + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 805  IETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKALREKFEWAIK 864

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 865  SVDEDWEF 872

[167][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
          Length = 998

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 32/59 (54%), Positives = 44/59 (74%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            IE M+   + KED + VALGTS+INY+DPR+TV + ++  VPIEK F++SL  KF WA+
Sbjct: 931  IETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAI 989

[168][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
          Length = 886

 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 32/59 (54%), Positives = 44/59 (74%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M+   + KED + VALGTS+INY+DPR+TV + ++  VPIEK F++SL  KF WA+
Sbjct: 819 IETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAI 877

[169][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
          Length = 760

 Score = 68.6 bits (166), Expect = 2e-10
 Identities = 29/59 (49%), Positives = 46/59 (77%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           +  M+  +K KED  +VALGTS++NY+DPR+TV + ++++VPIEK+F ++L  KF WA+
Sbjct: 693 VTTMRMQLKDKEDNSSVALGTSKMNYIDPRLTVKFSKKYDVPIEKLFTKTLRDKFQWAI 751

[170][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
           topoisomerase I n=1 Tax=Candida glabrata
           RepID=Q6FNH4_CANGA
          Length = 744

 Score = 68.2 bits (165), Expect = 3e-10
 Identities = 28/53 (52%), Positives = 43/53 (81%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KE+   V+LGTS+INY+DPR++V +C+++ VPIEKIF ++L  KF WA++
Sbjct: 684 LKDKEENSQVSLGTSKINYIDPRLSVVFCKKYNVPIEKIFTKTLREKFAWAIE 736

[171][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
           RepID=B3GD31_9CARA
          Length = 247

 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 27/55 (49%), Positives = 46/55 (83%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           ++K++     +++ +T+ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 192 LKKLEVQETDRDENKTIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[172][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
           RepID=C5DTC9_ZYGRC
          Length = 843

 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 29/60 (48%), Positives = 45/60 (75%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           IE     ++ KE+   V+LGTS+INY+DPR++V +C+++ VPIE+IF +SL  KF WA++
Sbjct: 776 IETSSIQLRDKEENSQVSLGTSKINYIDPRLSVVFCKKYGVPIERIFTKSLREKFKWAIE 835

[173][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
            RepID=C4JVV4_UNCRE
          Length = 889

 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 33/68 (48%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++ +VPIEK F+++L  KF WA+ 
Sbjct: 822  IETMSLQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLREKFDWAIK 881

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 882  SVDEDWEF 889

[174][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
           RepID=A1D4R5_NEOFI
          Length = 886

 Score = 67.4 bits (163), Expect = 5e-10
 Identities = 31/59 (52%), Positives = 44/59 (74%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M+   + KE+ + VALGTS+INY+DPR+TV + ++  VPIEK F++SL  KF WA+
Sbjct: 819 IETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAI 877

[175][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
          Length = 852

 Score = 67.0 bits (162), Expect = 6e-10
 Identities = 28/42 (66%), Positives = 37/42 (88%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVP 293
           IE +++ ++ KE+L+TVALGTS+INYLDPRITVAWC+RH  P
Sbjct: 811 IENIEKQIETKEELKTVALGTSKINYLDPRITVAWCERHRFP 852

[176][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
          Length = 763

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 30/67 (44%), Positives = 43/67 (64%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I +M+  M  K   +T ALGTS+INY+DPR+T AWC ++ V IE++F ++L   F WA  
Sbjct: 697 IHQMKALMIDKAQNKTTALGTSKINYIDPRLTYAWCAKYGVNIERVFTKTLRETFAWAAS 756

Query: 238 VXPDFRF 218
              D+ F
Sbjct: 757 TTADWEF 763

[177][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
            RepID=C6HAF8_AJECH
          Length = 909

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 33/68 (48%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 842  IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIK 901

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 902  SVDEDWEF 909

[178][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4XZS7_CLAL4
          Length = 764

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 28/53 (52%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++  VPIEK+F ++L  KFTWA++
Sbjct: 704 LKDKEDNSEVSLGTSKLNYIDPRLTVMFAKKFNVPIEKLFTKTLREKFTWAIE 756

[179][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
            RepID=C0NC53_AJECG
          Length = 909

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 33/68 (48%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 842  IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIK 901

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 902  SVDEDWEF 909

[180][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
           RepID=B6QNQ2_PENMQ
          Length = 860

 Score = 66.6 bits (161), Expect = 8e-10
 Identities = 33/68 (48%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
           IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 793 IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIK 852

Query: 241 DVXPDFRF 218
            V  D+ F
Sbjct: 853 SVEEDWEF 860

[181][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
           RepID=B3GD22_9COLE
          Length = 247

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 27/55 (49%), Positives = 45/55 (81%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           + K++     +++ +T+ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 192 LTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIYNKTQRDKF 246

[182][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
            RepID=B8MH68_TALSN
          Length = 864

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 33/68 (48%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 797  IETMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIK 856

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 857  SVDEDWEF 864

[183][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
            RepID=B2WCA4_PYRTR
          Length = 905

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 31/59 (52%), Positives = 44/59 (74%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            IE M+  M+ KE  + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+
Sbjct: 838  IENMKIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFGVPIEKFFSKTLREKFDWAI 896

[184][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
           RepID=UPI000069F011
          Length = 503

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 30/66 (45%), Positives = 47/66 (71%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           +M+     +E+ + +AL TS++NYLDPRI+VAWC++  V +EKI+N++   KF WA+D+ 
Sbjct: 438 RMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKIYNKTYRDKFAWAVDMT 497

Query: 235 XPDFRF 218
             DF F
Sbjct: 498 ETDFIF 503

[185][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
          Length = 503

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 30/66 (45%), Positives = 47/66 (71%), Gaps = 1/66 (1%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV- 236
           +M+     +E+ + +AL TS++NYLDPRI+VAWC++  V +EKI+N++   KF WA+D+ 
Sbjct: 438 RMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKIYNKTYRDKFAWAIDMT 497

Query: 235 XPDFRF 218
             DF F
Sbjct: 498 ETDFIF 503

[186][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
           RepID=B3GD23_9DYTI
          Length = 247

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 26/55 (47%), Positives = 46/55 (83%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           ++K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 192 LKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[187][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
           topoisomerase I n=1 Tax=Candida glabrata
           RepID=Q6FVE9_CANGA
          Length = 717

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 32/68 (47%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I   Q  ++ +E    V+LGTS+INY+DPR++V +C+++ VPIEKIF +SL  KF WA++
Sbjct: 650 ISTSQVQLQDREANSEVSLGTSKINYIDPRLSVVFCKKYGVPIEKIFTKSLREKFKWAIE 709

Query: 238 -VXPDFRF 218
            V   +RF
Sbjct: 710 SVDETWRF 717

[188][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
            RepID=Q1DXZ1_COCIM
          Length = 905

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 30/59 (50%), Positives = 43/59 (72%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            I+ M    + KED + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+
Sbjct: 838  IDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVPIEKFFSKTLREKFDWAI 896

[189][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
            delta SOWgp RepID=C5P0Y8_COCP7
          Length = 905

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 30/59 (50%), Positives = 43/59 (72%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            I+ M    + KED + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+
Sbjct: 838  IDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVPIEKFFSKTLREKFDWAI 896

[190][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
            1980 UF-70 RepID=A7EXF7_SCLS1
          Length = 911

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 31/64 (48%), Positives = 44/64 (68%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I  M    + +E  + VALGTS+INY+DPR+TV + Q+ +VPIEK F+++L  KF WA+D
Sbjct: 842  IANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVPIEKFFSKTLREKFAWAID 901

Query: 238  VXPD 227
               D
Sbjct: 902  SIKD 905

[191][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
            B05.10 RepID=A6S3Q9_BOTFB
          Length = 912

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 31/64 (48%), Positives = 44/64 (68%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I  M    + +E  + VALGTS+INY+DPR+TV + Q+ +VPIEK F+++L  KF WA+D
Sbjct: 843  IANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVPIEKFFSKTLREKFAWAID 902

Query: 238  VXPD 227
               D
Sbjct: 903  SIKD 906

[192][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
           RepID=A5E508_LODEL
          Length = 849

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 30/61 (49%), Positives = 46/61 (75%), Gaps = 1/61 (1%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFR 221
           +K KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++    D+R
Sbjct: 789 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLREKFKWAIESTDKDWR 848

Query: 220 F 218
           F
Sbjct: 849 F 849

[193][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
           Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
          Length = 786

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 29/60 (48%), Positives = 44/60 (73%), Gaps = 3/60 (5%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFN---QSLLAKFTWAM 242
           K++     +E+ + +ALGTS++NYLDPRI+VAWC+++ +PIEKI+N   +SLL    W M
Sbjct: 719 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGIPIEKIYNKTQRSLLGPLIWRM 778

[194][TOP]
>UniRef100_Q70HS8 DNA topoisomerase I subunit B (Fragment) n=1 Tax=Leishmania
           panamensis RepID=Q70HS8_9TRYP
          Length = 269

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 28/62 (45%), Positives = 46/62 (74%), Gaps = 3/62 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS+INY+DPRI  +W +  +VPI K+F+ ++L KF WA
Sbjct: 202 ERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATILKKFPWA 261

Query: 244 MD 239
           M+
Sbjct: 262 MN 263

[195][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
            RepID=C5GB81_AJEDR
          Length = 911

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 32/68 (47%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + +E+ + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA+ 
Sbjct: 844  IENMSLQAEDRENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIK 903

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 904  SVEEDWEF 911

[196][TOP]
>UniRef100_Q38EP5 DNA topoisomerase type IB small subunit n=1 Tax=Trypanosoma brucei
           RepID=Q38EP5_9TRYP
          Length = 273

 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 28/67 (41%), Positives = 46/67 (68%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++ ++  +K K+D +TV+LGTS++NY+DPRI  +W   + VPI ++F+ +L  KF WA+ 
Sbjct: 208 LKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALK 267

Query: 238 VXPDFRF 218
              DF F
Sbjct: 268 AR-DFTF 273

[197][TOP]
>UniRef100_C9ZXZ7 DNA topoisomerase type IB small subunit, putative n=2
           Tax=Trypanosoma brucei RepID=C9ZXZ7_TRYBG
          Length = 273

 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 28/67 (41%), Positives = 46/67 (68%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++ ++  +K K+D +TV+LGTS++NY+DPRI  +W   + VPI ++F+ +L  KF WA+ 
Sbjct: 208 LKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALK 267

Query: 238 VXPDFRF 218
              DF F
Sbjct: 268 AR-DFTF 273

[198][TOP]
>UniRef100_A4H3S7 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania
           braziliensis RepID=A4H3S7_LEIBR
          Length = 269

 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 28/61 (45%), Positives = 45/61 (73%), Gaps = 3/61 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS+INY+DPRI  +W +  +VPI K+F+ ++L KF WA
Sbjct: 202 ERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATILKKFPWA 261

Query: 244 M 242
           M
Sbjct: 262 M 262

[199][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
           RepID=B3GD42_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 44/53 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[200][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
           RepID=B3GD39_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 44/53 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[201][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
           RepID=B3GD38_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 44/53 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[202][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
           RepID=B3GD37_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 28/55 (50%), Positives = 45/55 (81%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           +E M+ D   +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 195 LEVMETD---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[203][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
           RepID=B3GD34_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTXRDKF 246

[204][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
           RepID=B3GD30_METCO
          Length = 281

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 44/53 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 228 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 280

[205][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
           RepID=B3GD29_9CARA
          Length = 247

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 44/53 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKAQRDKF 246

[206][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
          Length = 763

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++ KED   VALGTS++NY+DPR+T  + ++++VPIEK+F+++L  KF WA++
Sbjct: 703 LQDKEDNSQVALGTSKLNYIDPRLTAMFSKKYDVPIEKLFSKTLREKFAWAIE 755

[207][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
           RepID=B9WIH6_CANDC
          Length = 777

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 27/53 (50%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++
Sbjct: 717 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLREKFNWAIE 769

[208][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
           RepID=B3GD43_9CARA
          Length = 247

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[209][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
           RepID=B3GD36_9CARA
          Length = 247

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[210][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
           RepID=B3GD35_9CARA
          Length = 247

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[211][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
           RepID=B3GD33_9CARA
          Length = 247

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRHKF 246

[212][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
           RepID=B3GD32_9CARA
          Length = 247

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 26/53 (49%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     +++ + +ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 194 KLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[213][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
           RepID=B3GD28_CALSB
          Length = 281

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 27/53 (50%), Positives = 43/53 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           K++     K++ +++ALGTS++NYLDPRI+VAWC+++ VPIEKI+N++   KF
Sbjct: 228 KLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKF 280

[214][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
            RepID=C5FTA8_NANOT
          Length = 896

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 31/68 (45%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM- 242
            IE M    + KE+ + VALGTS++NY+DPR+TV + ++  VPIEK F++++  KF WA+ 
Sbjct: 829  IENMLLQAEDKENNKEVALGTSKLNYIDPRLTVVFSKKFNVPIEKFFSKTMREKFDWAIK 888

Query: 241  DVXPDFRF 218
             V  D+ F
Sbjct: 889  SVDEDWEF 896

[215][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
            RepID=C1H484_PARBA
          Length = 900

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 29/59 (49%), Positives = 43/59 (72%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VP+EK F+++L  KF WA+
Sbjct: 833  IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAI 891

[216][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
           RepID=C1GKM6_PARBD
          Length = 825

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 29/59 (49%), Positives = 43/59 (72%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VP+EK F+++L  KF WA+
Sbjct: 758 IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAI 816

[217][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
            RepID=C0SEQ3_PARBP
          Length = 905

 Score = 64.3 bits (155), Expect = 4e-09
 Identities = 29/59 (49%), Positives = 43/59 (72%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            IE M    + KE+ + VALGTS+INY+DPR+TV + ++  VP+EK F+++L  KF WA+
Sbjct: 838  IENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAI 896

[218][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
           RepID=B3GD41_9CARA
          Length = 247

 Score = 63.9 bits (154), Expect = 5e-09
 Identities = 25/45 (55%), Positives = 41/45 (91%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           +++ +++ALGTS++NYLDPRI+VAWC++++VPIEKI+N++   KF
Sbjct: 202 RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246

[219][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
           RepID=C5M985_CANTT
          Length = 777

 Score = 63.9 bits (154), Expect = 5e-09
 Identities = 27/53 (50%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++
Sbjct: 717 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIE 769

[220][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
          Length = 780

 Score = 63.9 bits (154), Expect = 5e-09
 Identities = 27/53 (50%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++
Sbjct: 720 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIE 772

[221][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
           CBS767 RepID=UPI00003BE191
          Length = 789

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 27/53 (50%), Positives = 41/53 (77%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++  VPIEK+F ++L  KF WA++
Sbjct: 729 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNVPIEKLFTKTLRDKFNWAIE 781

[222][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
           RepID=B3GD21_9COLE
          Length = 229

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 25/45 (55%), Positives = 40/45 (88%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKF 254
           +++ +++ALGTS++NYLDPRITVAWC+++ VPIEK++N++   KF
Sbjct: 184 RDENKSIALGTSKLNYLDPRITVAWCKKYGVPIEKVYNKTQRDKF 228

[223][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
          Length = 789

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 27/53 (50%), Positives = 41/53 (77%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+TV + ++  VPIEK+F ++L  KF WA++
Sbjct: 729 LKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNVPIEKLFTKTLRDKFNWAIE 781

[224][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
            RepID=A4R0K7_MAGGR
          Length = 906

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 28/59 (47%), Positives = 41/59 (69%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
            I  M+     ++  + VALGTS+INY+DPR+TV +C +  VPIEK F+++L  KF WA+
Sbjct: 837  IRTMELQAADRDGNKEVALGTSKINYIDPRLTVVFCNKMNVPIEKFFSKTLREKFNWAI 895

[225][TOP]
>UniRef100_Q95Z89 Possible DNA topoisomerase I-related protein n=1 Tax=Leishmania
           major RepID=Q95Z89_LEIMA
          Length = 262

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/62 (45%), Positives = 45/62 (72%), Gaps = 3/62 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS+INY+DPRI  +W +  +VPI KIF+ ++  KF WA
Sbjct: 195 ERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWA 254

Query: 244 MD 239
           M+
Sbjct: 255 MN 256

[226][TOP]
>UniRef100_Q8WQM6 DNA topoisomerase I-like protein n=1 Tax=Leishmania donovani
           RepID=Q8WQM6_LEIDO
          Length = 262

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/62 (45%), Positives = 45/62 (72%), Gaps = 3/62 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS+INY+DPRI  +W +  +VPI KIF+ ++  KF WA
Sbjct: 195 ERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWA 254

Query: 244 MD 239
           M+
Sbjct: 255 MN 256

[227][TOP]
>UniRef100_Q5RL92 Type IB topoisomerase small subunit n=1 Tax=Trypanosoma cruzi
           RepID=Q5RL92_TRYCR
          Length = 271

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/61 (45%), Positives = 44/61 (72%), Gaps = 3/61 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS++NY+DPRI  +W + + VPI KIF+ +L  KF WA
Sbjct: 204 ERLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWA 263

Query: 244 M 242
           M
Sbjct: 264 M 264

[228][TOP]
>UniRef100_Q4DUD0 DNA topoisomerase type IB small subunit, putative n=1
           Tax=Trypanosoma cruzi RepID=Q4DUD0_TRYCR
          Length = 272

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/61 (45%), Positives = 44/61 (72%), Gaps = 3/61 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS++NY+DPRI  +W + + VPI KIF+ +L  KF WA
Sbjct: 205 ERLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWA 264

Query: 244 M 242
           M
Sbjct: 265 M 265

[229][TOP]
>UniRef100_A4HS02 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania infantum
           RepID=A4HS02_LEIIN
          Length = 262

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/62 (45%), Positives = 45/62 (72%), Gaps = 3/62 (4%)
 Frame = -3

Query: 415 EKMQRD---MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWA 245
           E++ R+   ++ K+D + V+LGTS+INY+DPRI  +W +  +VPI KIF+ ++  KF WA
Sbjct: 195 ERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWA 254

Query: 244 MD 239
           M+
Sbjct: 255 MN 256

[230][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
           6260 RepID=UPI000151AE34
          Length = 754

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 26/53 (49%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++ KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++
Sbjct: 694 LQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIE 746

[231][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
           RepID=A5DLX4_PICGU
          Length = 754

 Score = 62.8 bits (151), Expect = 1e-08
 Identities = 26/53 (49%), Positives = 42/53 (79%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           ++ KED   V+LGTS++NY+DPR+TV + ++ +VPIEK+F ++L  KF WA++
Sbjct: 694 LQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIE 746

[232][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
           RepID=Q59XR0_CANAL
          Length = 780

 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 26/53 (49%), Positives = 41/53 (77%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+ V + ++ +VPIEK+F ++L  KF WA++
Sbjct: 720 LKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIE 772

[233][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
           RepID=Q59WV6_CANAL
          Length = 780

 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 26/53 (49%), Positives = 41/53 (77%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+ V + ++ +VPIEK+F ++L  KF WA++
Sbjct: 720 LKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIE 772

[234][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
          Length = 829

 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 25/48 (52%), Positives = 40/48 (83%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQS 269
           K++     +E+ + +ALGTS++NYLDPRI+VAWC+++ VPIEKI+N++
Sbjct: 756 KLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKT 803

[235][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
          Length = 778

 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 26/53 (49%), Positives = 41/53 (77%)
 Frame = -3

Query: 397 MKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           +K KED   V+LGTS++NY+DPR+ V + ++ +VPIEK+F ++L  KF WA++
Sbjct: 718 LKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIE 770

[236][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
           RepID=UPI00016E5F97
          Length = 790

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 25/48 (52%), Positives = 39/48 (81%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQS 269
           K+Q     +E+ + +ALGTS++NYLDPRI+VAWC++  +PIEKI+N++
Sbjct: 740 KLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKT 787

[237][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
          Length = 904

 Score = 61.6 bits (148), Expect = 3e-08
 Identities = 28/64 (43%), Positives = 44/64 (68%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I+ ++     +E  + VALGTS+INY+DPR+TV + ++  VPIEK F+++L  KF WA++
Sbjct: 835  IKTLELQCADREGNKEVALGTSKINYIDPRLTVVFAKKFNVPIEKFFSKTLRDKFKWAIE 894

Query: 238  VXPD 227
               D
Sbjct: 895  SVGD 898

[238][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
            RepID=Q2HDT9_CHAGB
          Length = 907

 Score = 61.2 bits (147), Expect = 3e-08
 Identities = 28/64 (43%), Positives = 42/64 (65%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I  ++     +E  + VALGTS+INY+DPR+TV +  + +VPIEK F+++L  KF WA+ 
Sbjct: 838  IRTLEMQSADREGNKEVALGTSKINYIDPRLTVVFSNKFQVPIEKFFSKTLRDKFNWAIQ 897

Query: 238  VXPD 227
               D
Sbjct: 898  SVGD 901

[239][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
            RepID=UPI000023DEFB
          Length = 910

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 27/64 (42%), Positives = 45/64 (70%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I+ ++   + ++  + VALGTS+INY+DPR+TV + ++ +VPIEK F+++L  KF WA+ 
Sbjct: 841  IKTLELQAQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAIK 900

Query: 238  VXPD 227
               D
Sbjct: 901  SVED 904

[240][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
          Length = 874

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 27/60 (45%), Positives = 42/60 (70%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
           I+ ++     +E  + VALGTS+INY+DPR+TV +  +  VPIEK F+++L  KF WA++
Sbjct: 805 IKNLELQSADREGNKEVALGTSKINYIDPRLTVVFSAKFNVPIEKFFSKTLREKFKWAIE 864

[241][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
          Length = 909

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 27/64 (42%), Positives = 45/64 (70%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            I+ ++   + ++  + VALGTS+INY+DPR+TV + ++ +VPIEK F+++L  KF WA+ 
Sbjct: 840  IKTLELQAQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAIK 899

Query: 238  VXPD 227
               D
Sbjct: 900  SVED 903

[242][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
            RepID=C7YQG7_NECH7
          Length = 919

 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 26/64 (40%), Positives = 45/64 (70%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD 239
            ++ ++   + ++  + VALGTS+INY+DPR+TV + ++ +VPIEK F+++L  KF WA+ 
Sbjct: 850  VKVLETQAEDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAIK 909

Query: 238  VXPD 227
               D
Sbjct: 910  SVED 913

[243][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
            RepID=C9SIQ6_9PEZI
          Length = 891

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 24/63 (38%), Positives = 44/63 (69%)
 Frame = -3

Query: 415  EKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMDV 236
            + ++   + ++  + VALGTS++NY+DPR+TV + ++ +VPIEK F++++  KF WA+  
Sbjct: 824  KNLELQAQDRDGNKEVALGTSKLNYIDPRLTVVFSRKFDVPIEKFFSKTMREKFNWAIQS 883

Query: 235  XPD 227
              D
Sbjct: 884  VDD 886

[244][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
          Length = 2575

 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 23/45 (51%), Positives = 34/45 (75%)
 Frame = -3

Query: 418  IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEK 284
            + K Q     KE+ + +AL TS++NYLDPRI+VAWC+ H+VP++K
Sbjct: 2347 LHKKQIAKVDKEENKCIALSTSKLNYLDPRISVAWCKTHDVPVDK 2391

[245][TOP]
>UniRef100_UPI000179DDCD DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2)
           (TOP1mt). n=1 Tax=Bos taurus RepID=UPI000179DDCD
          Length = 620

 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 29/58 (50%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
 Frame = -3

Query: 388 KEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAMD-VXPDFRF 218
           KE  + VALGTS++  LDPRI V W ++ EVP+EK++ ++   K TWA+D V  DF F
Sbjct: 564 KEGSKQVALGTSELICLDPRIGVTWRKKSEVPVEKVY-KTQREKLTWALDMVGEDFEF 620

[246][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
           RepID=B3GD25_AMPLE
          Length = 268

 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 22/41 (53%), Positives = 35/41 (85%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPI 290
           K++     K++ +++ALGTS++NYLDPRI+VAWC+++EVPI
Sbjct: 228 KLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKKYEVPI 268

[247][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
           RepID=Q4YYG2_PLABE
          Length = 805

 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 22/41 (53%), Positives = 35/41 (85%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEV 296
           +E ++  MK ++D +T+ALGTS+INY+DPRITVA+C++ E+
Sbjct: 765 VELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQFEI 805

[248][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
           RepID=B3GD24_9DYTI
          Length = 234

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 20/43 (46%), Positives = 37/43 (86%)
 Frame = -3

Query: 418 IEKMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPI 290
           ++K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPI
Sbjct: 192 LKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234

[249][TOP]
>UniRef100_C3ZV88 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
           floridae RepID=C3ZV88_BRAFL
          Length = 299

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 26/57 (45%), Positives = 40/57 (70%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPIEKIFNQSLLAKFTWAM 242
           K++     KE+ + +ALGTS++NYLDPRI+VA  + H   +EKI+N++   KF WA+
Sbjct: 246 KLEVQATDKEENKEIALGTSKLNYLDPRISVACGKSH---VEKIYNKTQRDKFAWAL 299

[250][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
           RepID=B3GD20_9NEOP
          Length = 234

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 20/41 (48%), Positives = 35/41 (85%)
 Frame = -3

Query: 412 KMQRDMKPKEDLQTVALGTSQINYLDPRITVAWCQRHEVPI 290
           K++     +++ +++ALGTS++NYLDPRI+VAWC++++VPI
Sbjct: 194 KLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234