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[1][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 129 bits (325), Expect = 9e-29
Identities = 66/85 (77%), Positives = 71/85 (83%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSALAIL NLG
Sbjct: 256 PAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLG 315
Query: 328 LIEETSIPRT----RPANAIQAKED 266
LIEE+ I R P N +AKED
Sbjct: 316 LIEESKITRALPWRPPTNVFRAKED 340
[2][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 129 bits (325), Expect = 9e-29
Identities = 64/85 (75%), Positives = 73/85 (85%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E+MAALEPIKDNEEAVKAYGIHLGTEMCKK+LAHG K+LHLYTLN+EKSALAIL NLG
Sbjct: 242 PVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
+I+E+ S+P RPAN + KED
Sbjct: 302 MIDESKISRSLPWRRPANVFRTKED 326
[3][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 128 bits (321), Expect = 3e-28
Identities = 64/85 (75%), Positives = 71/85 (83%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSALAIL NLG
Sbjct: 242 PSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLG 301
Query: 328 LIEETSI----PRTRPANAIQAKED 266
LIEE+ I P RP N + KED
Sbjct: 302 LIEESKISRPFPWRRPTNVFRVKED 326
[4][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 128 bits (321), Expect = 3e-28
Identities = 64/85 (75%), Positives = 71/85 (83%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EKSALAIL NLG
Sbjct: 242 PSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLG 301
Query: 328 LIEETSI----PRTRPANAIQAKED 266
LIEE+ I P RP N + KED
Sbjct: 302 LIEESKISRPFPWRRPTNVFRVKED 326
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 127 bits (320), Expect = 3e-28
Identities = 65/85 (76%), Positives = 70/85 (82%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSALAIL NLG
Sbjct: 253 PAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLG 312
Query: 328 LIEETSI----PRTRPANAIQAKED 266
LIEE+ I P P N + KED
Sbjct: 313 LIEESKITRPLPWRPPTNVFRVKED 337
[6][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 125 bits (313), Expect = 2e-27
Identities = 64/85 (75%), Positives = 70/85 (82%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAEI AAL+PIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK+ALAIL NLG
Sbjct: 230 PAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLG 289
Query: 328 LIEETSIPRT----RPANAIQAKED 266
LIEE+ + RT P N + KED
Sbjct: 290 LIEESKLSRTLPWRPPTNVFRVKED 314
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 124 bits (312), Expect = 3e-27
Identities = 65/85 (76%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL IL NLG
Sbjct: 242 PAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LIEE+ S+P P N + KED
Sbjct: 302 LIEESKISRSLPWRPPTNVFRVKED 326
[8][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 124 bits (312), Expect = 3e-27
Identities = 63/84 (75%), Positives = 69/84 (82%), Gaps = 4/84 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKI+AHG KTLHLYTLN+EKSALAIL NLG
Sbjct: 257 PAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLYTLNMEKSALAILMNLG 316
Query: 328 LIEETSI----PRTRPANAIQAKE 269
LIEE+ I P P N + KE
Sbjct: 317 LIEESKISRPLPWRPPTNVFRVKE 340
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 124 bits (312), Expect = 3e-27
Identities = 65/85 (76%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EKSAL IL NLG
Sbjct: 242 PAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LIEE+ S+P P N + KED
Sbjct: 302 LIEESKISRSLPWRPPTNVFRVKED 326
[10][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 122 bits (307), Expect = 1e-26
Identities = 62/77 (80%), Positives = 66/77 (85%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PA+IMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG TLHLYTLN+EKSALAIL NLG
Sbjct: 243 PADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMNLG 302
Query: 328 LIEETSIPRTRPANAIQ 278
LIEET +A+Q
Sbjct: 303 LIEETKFLGPYLGDALQ 319
[11][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 121 bits (304), Expect = 2e-26
Identities = 62/85 (72%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+EI AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EKSAL IL NLG
Sbjct: 242 PSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALGILANLG 301
Query: 328 LIEETSIPRTRP----ANAIQAKED 266
LI+ T I R P N ++ KE+
Sbjct: 302 LIDMTKIRRPLPWRPATNVLRTKEN 326
[12][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 119 bits (299), Expect = 9e-26
Identities = 59/85 (69%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+ IL NLG
Sbjct: 242 PAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LI+E+ S+P RPAN + KED
Sbjct: 302 LIDESKISRSLPWRRPANVFRTKED 326
[13][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 119 bits (299), Expect = 9e-26
Identities = 59/85 (69%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+ IL NLG
Sbjct: 52 PAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLG 111
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LI+E+ S+P RPAN + KED
Sbjct: 112 LIDESKISRSLPWRRPANVFRTKED 136
[14][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 119 bits (299), Expect = 9e-26
Identities = 59/85 (69%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+ IL NLG
Sbjct: 242 PAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LI+E+ S+P RPAN + KED
Sbjct: 302 LIDESKISRSLPWRRPANVFRTKED 326
[15][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 119 bits (299), Expect = 9e-26
Identities = 59/85 (69%), Positives = 69/85 (81%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++KSA+ IL NLG
Sbjct: 242 PAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLG 301
Query: 328 LIEET----SIPRTRPANAIQAKED 266
LI+E+ S+P RPAN + KED
Sbjct: 302 LIDESKISRSLPWRRPANVFRTKED 326
[16][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 117 bits (293), Expect = 4e-25
Identities = 59/85 (69%), Positives = 67/85 (78%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+EI AAL+PIKDNEEAVK YGIHLGTEMCKKILA G KTLHLYTLN++KSA+ IL NLG
Sbjct: 242 PSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLG 301
Query: 328 LIEETSIPRTRP----ANAIQAKED 266
LIEE+ + R P N + KED
Sbjct: 302 LIEESKVSRPLPWRPATNVFRVKED 326
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 116 bits (291), Expect = 8e-25
Identities = 59/85 (69%), Positives = 68/85 (80%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAEIMAALEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L IL+NLG
Sbjct: 242 PAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLG 301
Query: 328 LIE----ETSIPRTRPANAIQAKED 266
LI+ +P P N+ + KED
Sbjct: 302 LIDFSRVSRPLPWRPPTNSKRTKED 326
[18][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 116 bits (290), Expect = 1e-24
Identities = 58/85 (68%), Positives = 67/85 (78%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+EI AAL+PIKDNEEAV+ YGIHLGTEMCKKILA G KTLHLYTLN++KSA+ IL NLG
Sbjct: 242 PSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLG 301
Query: 328 LIEETSIPRTRP----ANAIQAKED 266
LIEE+ + R P N + KED
Sbjct: 302 LIEESKVSRPLPWRPATNVFRVKED 326
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 115 bits (288), Expect = 2e-24
Identities = 58/85 (68%), Positives = 68/85 (80%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAEIMA LEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEKS L IL+NLG
Sbjct: 242 PAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNLG 301
Query: 328 LIEETSI----PRTRPANAIQAKED 266
LI+ + + P P N+ + KED
Sbjct: 302 LIDFSKVTRPLPWRPPTNSKRTKED 326
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 94.7 bits (234), Expect = 3e-18
Identities = 53/85 (62%), Positives = 61/85 (71%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT L T++L +NLG
Sbjct: 242 PSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTFGL-TMDLP------WQNLG 294
Query: 328 LIEETSI----PRTRPANAIQAKED 266
LIEE+ I P RP N + KED
Sbjct: 295 LIEESKISRPFPWRRPTNVFRVKED 319
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 87.4 bits (215), Expect = 5e-16
Identities = 45/79 (56%), Positives = 58/79 (73%), Gaps = 1/79 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
PAEI ALE IKDN+EAVKAYGI LG MC+++LA G +H+YTLNLEKSA+AIL+ L
Sbjct: 236 PAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAVAILEQL 295
Query: 331 GLIEETSIPRTRPANAIQA 275
GL++ + + R P + A
Sbjct: 296 GLVDTSRVQRPLPWRHVPA 314
[22][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 70.9 bits (172), Expect = 5e-11
Identities = 34/62 (54%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L T+MC+ +L G LH+YTLNLE + + ILKNL
Sbjct: 249 PEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLETATIQILKNL 308
Query: 331 GL 326
GL
Sbjct: 309 GL 310
[23][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 68.9 bits (167), Expect = 2e-10
Identities = 34/62 (54%), Positives = 42/62 (67%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P IM LEPIKDN+E VK YG+ L EM K++L G + LH YTLNLE+S +LK L
Sbjct: 235 PQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVLKGLQ 294
Query: 328 LI 323
L+
Sbjct: 295 LV 296
[24][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 68.9 bits (167), Expect = 2e-10
Identities = 30/68 (44%), Positives = 44/68 (64%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P M L P+KD++E V+ G+ L EMC+K++A G LH YT+NLEK+ I++ LG
Sbjct: 233 PQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIERLG 292
Query: 328 LIEETSIP 305
L++E P
Sbjct: 293 LLDENLAP 300
[25][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 66.6 bits (161), Expect = 9e-10
Identities = 30/65 (46%), Positives = 46/65 (70%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P MA L+P+KD+++AV+ G L +MC+K+L G+ T LH+YT+NLEK+ + +L L
Sbjct: 236 PEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACIMVLDRL 295
Query: 331 GLIEE 317
GL+ E
Sbjct: 296 GLLSE 300
[26][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 66.2 bits (160), Expect = 1e-09
Identities = 33/64 (51%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P E + LEP+KD+++AV+ G L +MC+KILA G T LHLYT+NLE+++L IL+ L
Sbjct: 236 PPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASLMILERL 295
Query: 331 GLIE 320
LI+
Sbjct: 296 QLID 299
[27][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 65.9 bits (159), Expect = 2e-09
Identities = 35/86 (40%), Positives = 50/86 (58%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ IL LG
Sbjct: 233 PPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELG 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHKTPLQKPLPWRQSLGLGRREE 318
[28][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 65.9 bits (159), Expect = 2e-09
Identities = 35/86 (40%), Positives = 50/86 (58%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL+++ IL LG
Sbjct: 233 PPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELG 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHKTPLQKPLPWRQSLGLGRREE 318
[29][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 65.9 bits (159), Expect = 2e-09
Identities = 31/72 (43%), Positives = 46/72 (63%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AVK G L +MC+++LA G K LH YT+NL ++ A+L+ L
Sbjct: 233 PPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELK 292
Query: 328 LIEETSIPRTRP 293
LI P RP
Sbjct: 293 LIPSEETPLQRP 304
[30][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 65.5 bits (158), Expect = 2e-09
Identities = 32/65 (49%), Positives = 42/65 (64%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L MCK++LA G LH YTLN E + + +LK L
Sbjct: 271 PQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEVLKRL 330
Query: 331 GLIEE 317
G+ E
Sbjct: 331 GMWNE 335
[31][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P EI A +EPIKDN+ A++ YGI L MC+++L G + LH YTLN E + + +LK L
Sbjct: 274 PQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEVLKRL 333
Query: 331 GLIEE 317
G+ E
Sbjct: 334 GIWNE 338
[32][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 65.1 bits (157), Expect = 3e-09
Identities = 32/72 (44%), Positives = 44/72 (61%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E + ALEP+K+++ AVK G L EMC+K+LA G LH YT+NL ++ ++L L
Sbjct: 233 PPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQATQSVLDELK 292
Query: 328 LIEETSIPRTRP 293
LI P RP
Sbjct: 293 LIPSEETPLQRP 304
[33][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 64.7 bits (156), Expect = 3e-09
Identities = 35/86 (40%), Positives = 49/86 (56%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P M ALEP K+++ AVK G L +EMC+KIL G + LH YT+NL +S +L+ L
Sbjct: 233 PPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQSTKMVLEELD 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI + P +P Q+ G +E
Sbjct: 293 LIPSSETPLQKPLPWRQSLGLGRREE 318
[34][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 64.3 bits (155), Expect = 4e-09
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +LK L
Sbjct: 271 PQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRL 330
Query: 331 GLIEE 317
G+ +E
Sbjct: 331 GMWKE 335
[35][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 64.3 bits (155), Expect = 4e-09
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +LK L
Sbjct: 271 PQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRL 330
Query: 331 GLIEE 317
G+ +E
Sbjct: 331 GMWKE 335
[36][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 64.3 bits (155), Expect = 4e-09
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +LK L
Sbjct: 271 PQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRL 330
Query: 331 GLIEE 317
G+ +E
Sbjct: 331 GMWKE 335
[37][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 63.9 bits (154), Expect = 6e-09
Identities = 32/65 (49%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI EMCK +LA G LH YTLN E + + +L+ L
Sbjct: 277 PEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEVLRQL 336
Query: 331 GLIEE 317
GL E
Sbjct: 337 GLWAE 341
[38][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 63.9 bits (154), Expect = 6e-09
Identities = 35/86 (40%), Positives = 53/86 (61%), Gaps = 5/86 (5%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA-HGFKTLHLYTLNLEKSALAILKNL 332
P I+ +E IKDN+EA++ +GI T +CKK+LA +H+YTLN E++ + +LK +
Sbjct: 260 PQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKLLKRV 319
Query: 331 GLIEETSIPRTRP----ANAIQAKED 266
GL E SI ++ P AN + ED
Sbjct: 320 GLWHEESIYKSLPWRPSANGKRISED 345
[39][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 63.9 bits (154), Expect = 6e-09
Identities = 35/93 (37%), Positives = 56/93 (60%), Gaps = 1/93 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + LEP+KD+++ V+ G L +MC+KIL G+ K LH+YT+NLEK+ L IL+ L
Sbjct: 238 PQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILEKL 297
Query: 331 GLIEETSIPRTRPANAIQAKEDGENQERPTEDM 233
GL+ S P ++ ++ N +R E++
Sbjct: 298 GLLPSESEVNANPLASLPWRK-SLNPKRKNEEV 329
[40][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 63.9 bits (154), Expect = 6e-09
Identities = 30/72 (41%), Positives = 45/72 (62%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+L+ L
Sbjct: 233 PPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELK 292
Query: 328 LIEETSIPRTRP 293
LI P RP
Sbjct: 293 LIPSEETPLQRP 304
[41][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 63.9 bits (154), Expect = 6e-09
Identities = 30/72 (41%), Positives = 45/72 (62%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ A+L+ L
Sbjct: 233 PPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELK 292
Query: 328 LIEETSIPRTRP 293
LI P RP
Sbjct: 293 LIPSEETPLQRP 304
[42][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 63.5 bits (153), Expect = 8e-09
Identities = 32/65 (49%), Positives = 42/65 (64%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI + LEPIKDN+ A++ YGI L EMC+ +L G LH YTLN E + + +L+ L
Sbjct: 281 PEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQL 340
Query: 331 GLIEE 317
GL E
Sbjct: 341 GLWTE 345
[43][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 63.2 bits (152), Expect = 1e-08
Identities = 31/72 (43%), Positives = 44/72 (61%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P M ALEP+K+++ AVK G L +EMC+K+L +G LH YT+NL +S +L+ L
Sbjct: 233 PKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQSTTMVLEELN 292
Query: 328 LIEETSIPRTRP 293
L T P +P
Sbjct: 293 LKPSTETPLQKP 304
[44][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 62.4 bits (150), Expect = 2e-08
Identities = 28/61 (45%), Positives = 39/61 (63%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+ +++ LE + DN+EA AYGI TE C ++L G LH+YTLN S + +LKNL
Sbjct: 241 PSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAPSTIQVLKNLA 300
Query: 328 L 326
L
Sbjct: 301 L 301
[45][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 62.4 bits (150), Expect = 2e-08
Identities = 27/37 (72%), Positives = 32/37 (86%)
Frame = -1
Query: 502 EIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK 392
++ AALEPIKDNE+AV YGIHLGTEMCKK+L +G K
Sbjct: 19 KVTAALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK 55
[46][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 62.4 bits (150), Expect = 2e-08
Identities = 33/86 (38%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L LG
Sbjct: 233 PPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELG 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHETPLQKPLPWRQSLGLGRREE 318
[47][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 62.4 bits (150), Expect = 2e-08
Identities = 33/86 (38%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L LG
Sbjct: 233 PPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELG 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHETPLQKPLPWRQSLGLGRREE 318
[48][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 62.4 bits (150), Expect = 2e-08
Identities = 33/86 (38%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL+++ +L LG
Sbjct: 233 PPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELG 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHETPLQKPLPWRQSLGLGRREE 318
[49][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +LK L
Sbjct: 300 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRL 359
Query: 331 GLIEE 317
G+ E
Sbjct: 360 GMWTE 364
[50][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +LK L
Sbjct: 318 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRL 377
Query: 331 GLIEE 317
G+ E
Sbjct: 378 GMWTE 382
[51][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE++ + IL+NL
Sbjct: 233 PQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENL 292
Query: 331 GLIE 320
LIE
Sbjct: 293 NLIE 296
[52][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +LK L
Sbjct: 277 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRL 336
Query: 331 GLIEE 317
G+ E
Sbjct: 337 GMWTE 341
[53][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +LK L
Sbjct: 307 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRL 366
Query: 331 GLIEE 317
G+ E
Sbjct: 367 GMWTE 371
[54][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 62.0 bits (149), Expect = 2e-08
Identities = 29/72 (40%), Positives = 44/72 (61%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AVK G L +MC++++A G K LH YT+NL +S +L+ L
Sbjct: 233 PPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVLEELE 292
Query: 328 LIEETSIPRTRP 293
L P RP
Sbjct: 293 LTPTAEAPIPRP 304
[55][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 62.0 bits (149), Expect = 2e-08
Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE++ + IL+NL
Sbjct: 233 PQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENL 292
Query: 331 GLIE 320
LIE
Sbjct: 293 NLIE 296
[56][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 61.6 bits (148), Expect = 3e-08
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +LK L
Sbjct: 279 PQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRL 338
Query: 331 GLIEE 317
GL E
Sbjct: 339 GLWNE 343
[57][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 61.6 bits (148), Expect = 3e-08
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +LK L
Sbjct: 279 PQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRL 338
Query: 331 GLIEE 317
GL E
Sbjct: 339 GLWNE 343
[58][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/70 (45%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +L+ L
Sbjct: 281 PEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQL 340
Query: 331 GL-IEETSIP 305
GL IE+ P
Sbjct: 341 GLWIEDPRRP 350
[59][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 61.6 bits (148), Expect = 3e-08
Identities = 32/70 (45%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +L+ L
Sbjct: 281 PEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQL 340
Query: 331 GL-IEETSIP 305
GL IE+ P
Sbjct: 341 GLWIEDPRRP 350
[60][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 61.6 bits (148), Expect = 3e-08
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 10/90 (11%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + AL+PIKD++ V+ G L +EMC+K+L G+ LH YT+NLEK+ + IL+ L
Sbjct: 233 PQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMILEKL 292
Query: 331 GLIEE---------TSIPRTRPANAIQAKE 269
LIE T +P + N ++KE
Sbjct: 293 NLIEAVKSNEIVGVTELPWRKSLNPERSKE 322
[61][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 61.6 bits (148), Expect = 3e-08
Identities = 30/72 (41%), Positives = 44/72 (61%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P+E M ALEP+K+++ AV+ G L MC++++A G K LH YT+NL ++ +LK L
Sbjct: 233 PSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELE 292
Query: 328 LIEETSIPRTRP 293
L P RP
Sbjct: 293 LTPSEDSPIQRP 304
[62][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 61.2 bits (147), Expect = 4e-08
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +LK L
Sbjct: 300 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRL 359
Query: 331 GLIEE 317
G+ E
Sbjct: 360 GMWTE 364
[63][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 61.2 bits (147), Expect = 4e-08
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +LK L
Sbjct: 318 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRL 377
Query: 331 GLIEE 317
G+ E
Sbjct: 378 GMWTE 382
[64][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 61.2 bits (147), Expect = 4e-08
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +LK L
Sbjct: 277 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRL 336
Query: 331 GLIEE 317
G+ E
Sbjct: 337 GMWTE 341
[65][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 60.8 bits (146), Expect = 5e-08
Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +LK L
Sbjct: 135 PQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRL 194
Query: 331 GLIEE 317
G+ E
Sbjct: 195 GIWNE 199
[66][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 60.8 bits (146), Expect = 5e-08
Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +LK L
Sbjct: 267 PQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRL 326
Query: 331 GLIEE 317
G+ E
Sbjct: 327 GIWNE 331
[67][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 60.8 bits (146), Expect = 5e-08
Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 4/85 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI A+EPI+DN+EA++ YG+H M +++ G LH YTLN E + + ILK +
Sbjct: 266 PDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQILKQI 325
Query: 331 GLIEE---TSIPRTRPANAIQAKED 266
GL E P R AN + +E+
Sbjct: 326 GLWTEDIQRPWPWKRTANYNRCEEE 350
[68][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 60.8 bits (146), Expect = 5e-08
Identities = 29/72 (40%), Positives = 43/72 (59%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +S +L+ L
Sbjct: 233 PPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVLEELN 292
Query: 328 LIEETSIPRTRP 293
L P +P
Sbjct: 293 LTPSEETPLQKP 304
[69][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 60.5 bits (145), Expect = 6e-08
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P + A +E IKD+ AVKA+G+ G EMC+ +LA G LH YTLNLEK +L L
Sbjct: 316 PETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLEKVVYGVLDAL 375
Query: 331 G 329
G
Sbjct: 376 G 376
[70][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 60.5 bits (145), Expect = 6e-08
Identities = 27/68 (39%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + LEP+KD+++ V+ G L E+C+K+L G+ LH+YT+NLEK++L IL+ L
Sbjct: 238 PDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLEKASLMILEKL 297
Query: 331 GLIEETSI 308
L++ +++
Sbjct: 298 DLLKRSNV 305
[71][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 60.5 bits (145), Expect = 6e-08
Identities = 26/64 (40%), Positives = 42/64 (65%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ALEP+KD++ V+ G L EMC+K++ +G LH YT+NLEK+ I++ +G
Sbjct: 234 PQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKATKMIIEKMG 293
Query: 328 LIEE 317
L+ +
Sbjct: 294 LLNQ 297
[72][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 60.1 bits (144), Expect = 8e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +LK L
Sbjct: 276 PQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRL 335
Query: 331 GL-IEETSIP 305
GL IE+ P
Sbjct: 336 GLWIEDPRRP 345
[73][TOP]
>UniRef100_A4FAF8 Methylenetetrahydrofolate reductase n=1 Tax=Saccharopolyspora
erythraea NRRL 2338 RepID=A4FAF8_SACEN
Length = 294
Score = 60.1 bits (144), Expect = 8e-08
Identities = 25/62 (40%), Positives = 40/62 (64%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P ++ LEP+ D+ A +A G+ L TE+C++++A G LH YTLN K+ ++ NLG
Sbjct: 229 PPAVLERLEPLADDAAAFRAEGVVLATELCERLIAEGVPALHFYTLNRSKATREVVSNLG 288
Query: 328 LI 323
L+
Sbjct: 289 LL 290
[74][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 60.1 bits (144), Expect = 8e-08
Identities = 33/62 (53%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTL---HLYTLNLEKSALAILK 338
P EI LEPIKD++EAVK G L EMC++ILA + H YTLNLE+SA IL
Sbjct: 259 PDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLNLERSATRILM 318
Query: 337 NL 332
L
Sbjct: 319 QL 320
[75][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 60.1 bits (144), Expect = 8e-08
Identities = 30/72 (41%), Positives = 42/72 (58%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +L+ L
Sbjct: 233 PESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELK 292
Query: 328 LIEETSIPRTRP 293
LI P +P
Sbjct: 293 LIPSYETPLQKP 304
[76][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 60.1 bits (144), Expect = 8e-08
Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+ L
Sbjct: 238 PQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERL 297
Query: 331 GLIEETSIPRTRPANAIQAKEDGENQERPTEDM 233
++ S P A+ N +R E++
Sbjct: 298 NILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[77][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 60.1 bits (144), Expect = 8e-08
Identities = 30/72 (41%), Positives = 42/72 (58%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL ++ +L+ L
Sbjct: 233 PESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELK 292
Query: 328 LIEETSIPRTRP 293
LI P +P
Sbjct: 293 LIPSYETPLQKP 304
[78][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 60.1 bits (144), Expect = 8e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +LK L
Sbjct: 276 PQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRL 335
Query: 331 GL-IEETSIP 305
GL IE+ P
Sbjct: 336 GLWIEDPRRP 345
[79][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 60.1 bits (144), Expect = 8e-08
Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+ L
Sbjct: 238 PQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERL 297
Query: 331 GLIEETSIPRTRPANAIQAKEDGENQERPTEDM 233
++ S P A+ N +R E++
Sbjct: 298 NILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[80][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 59.7 bits (143), Expect = 1e-07
Identities = 27/62 (43%), Positives = 39/62 (62%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PA+ + L+ + ++EAV AYGI TE C +L G LH YTLN +S + I++NLG
Sbjct: 234 PAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKARSTVQIVRNLG 293
Query: 328 LI 323
L+
Sbjct: 294 LL 295
[81][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 59.7 bits (143), Expect = 1e-07
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLEK+ + IL+ L
Sbjct: 233 PQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKL 292
Query: 331 GLIE 320
LIE
Sbjct: 293 NLIE 296
[82][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 59.7 bits (143), Expect = 1e-07
Identities = 32/86 (37%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++ +L L
Sbjct: 124 PPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELE 183
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 184 LIPSHKTPLQKPLPWRQSLGLGRREE 209
[83][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 59.7 bits (143), Expect = 1e-07
Identities = 32/86 (37%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL+++ +L L
Sbjct: 233 PPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELE 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 293 LIPSHKTPLQKPLPWRQSLGLGRREE 318
[84][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 59.7 bits (143), Expect = 1e-07
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLEK+ + IL+ L
Sbjct: 233 PQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKL 292
Query: 331 GLIE 320
LIE
Sbjct: 293 NLIE 296
[85][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 59.7 bits (143), Expect = 1e-07
Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+ L
Sbjct: 49 PQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERL 108
Query: 331 GLIEETSIPRTRPANAIQAKEDGENQERPTEDM 233
++ S P A+ N +R E++
Sbjct: 109 NILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 140
[86][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 59.7 bits (143), Expect = 1e-07
Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+ L
Sbjct: 238 PQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERL 297
Query: 331 GLIEETSIPRTRPANAIQAKEDGENQERPTEDM 233
++ S P A+ N +R E++
Sbjct: 298 NILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[87][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 59.3 bits (142), Expect = 1e-07
Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 317 PQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 376
Query: 331 GLIEE 317
G+ E
Sbjct: 377 GMWTE 381
[88][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 59.3 bits (142), Expect = 1e-07
Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 317 PQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 376
Query: 331 GLIEE 317
G+ E
Sbjct: 377 GMWTE 381
[89][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 59.3 bits (142), Expect = 1e-07
Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 317 PQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 376
Query: 331 GLIEE 317
G+ E
Sbjct: 377 GMWTE 381
[90][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 59.3 bits (142), Expect = 1e-07
Identities = 30/67 (44%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH-GFKTLHLYTLNLEKSALAILKNL 332
P +++ LEPIK ++ VK +GIHL +M K I G + HLYTLNLEKSA ++K L
Sbjct: 260 PEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLEKSATCVIKVL 319
Query: 331 GLIEETS 311
+ + S
Sbjct: 320 ADVPDQS 326
[91][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 59.3 bits (142), Expect = 1e-07
Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 276 PQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 335
Query: 331 GLIEE 317
G+ E
Sbjct: 336 GMWTE 340
[92][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 58.9 bits (141), Expect = 2e-07
Identities = 28/64 (43%), Positives = 43/64 (67%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + ALEPIKD++ V+ G L +EMC++++ G+ LH YT+NLEK+ + IL+ L
Sbjct: 234 PPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLEKATVMILEKL 293
Query: 331 GLIE 320
L+E
Sbjct: 294 NLVE 297
[93][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 58.9 bits (141), Expect = 2e-07
Identities = 29/74 (39%), Positives = 46/74 (62%), Gaps = 2/74 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L +MC++++A G LH YT+NL +S +L L
Sbjct: 233 PPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELN 292
Query: 328 LI--EETSIPRTRP 293
L+ EET + R P
Sbjct: 293 LMPSEETPLQRALP 306
[94][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 58.5 bits (140), Expect = 2e-07
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 282 PQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 341
Query: 331 GLIEE 317
G+ E
Sbjct: 342 GMWTE 346
[95][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 58.5 bits (140), Expect = 2e-07
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +LK L
Sbjct: 317 PQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQL 376
Query: 331 GLIEE 317
G+ E
Sbjct: 377 GMWTE 381
[96][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 58.5 bits (140), Expect = 2e-07
Identities = 28/68 (41%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P EI+ L+ K++ EA++A+GI T+MC+++ A G + +HLYTLN+EK ++IL+NL
Sbjct: 253 PNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILENL 312
Query: 331 GLIEETSI 308
+ +E +
Sbjct: 313 KISKEPEL 320
[97][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 58.5 bits (140), Expect = 2e-07
Identities = 27/64 (42%), Positives = 43/64 (67%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + AL PIK+++ A++ G L +EMC+K++ G+ LH YT+NLE+S + IL+ L
Sbjct: 236 PQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEKL 295
Query: 331 GLIE 320
L+E
Sbjct: 296 NLVE 299
[98][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 58.5 bits (140), Expect = 2e-07
Identities = 31/86 (36%), Positives = 48/86 (55%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + ALEP+K+++ AV+ G L MC+K+LA G LH YT+NL+++ +L L
Sbjct: 219 PPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGELE 278
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
LI P +P Q+ G +E
Sbjct: 279 LIPSHKTPLQKPLPWRQSLGLGRREE 304
[99][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 58.2 bits (139), Expect = 3e-07
Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P EI +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + +LK L
Sbjct: 276 PQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEVLKRL 335
Query: 331 GL 326
G+
Sbjct: 336 GM 337
[100][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 58.2 bits (139), Expect = 3e-07
Identities = 28/67 (41%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P + L P+ D++E V+ G L +MC+++L G + LHLYT+NLE+ L IL+ L
Sbjct: 226 PDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPLVILERL 285
Query: 331 GLIEETS 311
GL+ E S
Sbjct: 286 GLLPEAS 292
[101][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 58.2 bits (139), Expect = 3e-07
Identities = 28/64 (43%), Positives = 41/64 (64%), Gaps = 1/64 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P + LEPIKD++ V+ G L ++MC K+L GF LH YT+NLE++ + IL+ L
Sbjct: 233 PPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMILETL 292
Query: 331 GLIE 320
+IE
Sbjct: 293 NIIE 296
[102][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 57.8 bits (138), Expect = 4e-07
Identities = 31/86 (36%), Positives = 47/86 (54%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E MA LEP+K+++ AV+ G L EMC+KI+ G + LH YT+NL ++ +L+ L
Sbjct: 233 PEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEELD 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
+ + P R Q+ G E
Sbjct: 293 WLPSPNRPLKRALPWKQSLGSGRRDE 318
[103][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 57.4 bits (137), Expect = 5e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + + LEP+K+++ AVK G L +MC+++LA G LH YT+NL ++ +L L
Sbjct: 233 PEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELK 292
Query: 328 LI--EETSIPRTRP 293
L+ EET I R P
Sbjct: 293 LLPSEETPIQRPLP 306
[104][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 57.0 bits (136), Expect = 7e-07
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +LK L
Sbjct: 402 PQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRL 461
Query: 331 GL-IEETSIP 305
G+ IE+ P
Sbjct: 462 GMWIEDPRRP 471
[105][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 57.0 bits (136), Expect = 7e-07
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 2/70 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +LK L
Sbjct: 318 PQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRL 377
Query: 331 GL-IEETSIP 305
G+ IE+ P
Sbjct: 378 GMWIEDPRRP 387
[106][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 57.0 bits (136), Expect = 7e-07
Identities = 29/68 (42%), Positives = 41/68 (60%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E + LEPIK ++ AV+ G L E+C+KILA G LH YT+NL +S IL++L
Sbjct: 228 PEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLD 287
Query: 328 LIEETSIP 305
+ + P
Sbjct: 288 WLPSPNKP 295
[107][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 56.2 bits (134), Expect = 1e-06
Identities = 29/62 (46%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK+L
Sbjct: 269 PQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSL 328
Query: 331 GL 326
GL
Sbjct: 329 GL 330
[108][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 56.2 bits (134), Expect = 1e-06
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 2/64 (3%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH--GFKTLHLYTLNLEKSALAILKN 335
P + ALEPIK+++E V+ G L +MC++IL G + LH YT+NLEK +L+
Sbjct: 234 PQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEE 293
Query: 334 LGLI 323
L L+
Sbjct: 294 LNLV 297
[109][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 56.2 bits (134), Expect = 1e-06
Identities = 29/62 (46%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK+L
Sbjct: 290 PQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSL 349
Query: 331 GL 326
GL
Sbjct: 350 GL 351
[110][TOP]
>UniRef100_B5HCL5 Methylenetetrahydrofolate reductase n=1 Tax=Streptomyces
pristinaespiralis ATCC 25486 RepID=B5HCL5_STRPR
Length = 305
Score = 55.8 bits (133), Expect = 2e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PAE+ + +KD+ AV++ GI TE C ++LA G LH TLN + L I +NLG
Sbjct: 241 PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG 300
Query: 328 LIEET 314
L E++
Sbjct: 301 LHEQS 305
[111][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 55.8 bits (133), Expect = 2e-06
Identities = 27/62 (43%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKNL 332
P I+ +LEPIK++++AV+ +GI +C+ +L++G T +HL+TLN E S+ IL+ L
Sbjct: 288 PDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQL 347
Query: 331 GL 326
GL
Sbjct: 348 GL 349
[112][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 55.8 bits (133), Expect = 2e-06
Identities = 30/86 (34%), Positives = 46/86 (53%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ALEP+K+++ AV+ G L EMC+K+LA+G LH YT+NL ++ +L+ L
Sbjct: 233 PQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELN 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
P Q+K G +E
Sbjct: 293 WAPSAERPLQHALPWKQSKGLGRREE 318
[113][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK L
Sbjct: 291 PEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKAL 350
Query: 331 GL 326
GL
Sbjct: 351 GL 352
[114][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/68 (42%), Positives = 39/68 (57%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P I LE D+ E+++ +G + T MC+K+L G LH YTLN + +L I KNLG
Sbjct: 250 PRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKAGAPGLHFYTLNQVEPSLGIWKNLG 309
Query: 328 LIEETSIP 305
L E IP
Sbjct: 310 LGEREKIP 317
[115][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 55.5 bits (132), Expect = 2e-06
Identities = 25/61 (40%), Positives = 36/61 (59%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + ++ IKD+ +AVK +G+ G E+ + +L G K LH YTLNLEK I LG
Sbjct: 255 PKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKILHFYTLNLEKVVYGITDELG 314
Query: 328 L 326
+
Sbjct: 315 I 315
[116][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 55.5 bits (132), Expect = 2e-06
Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E S ILK L
Sbjct: 341 PEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKAL 400
Query: 331 GL 326
GL
Sbjct: 401 GL 402
[117][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 55.5 bits (132), Expect = 2e-06
Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILKNL 332
P + + LEP+KD++ V+ G L +MC+K+L G K LH YT+NLEK+ + +L+ L
Sbjct: 234 PQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERL 293
Query: 331 GLIEETS 311
L + S
Sbjct: 294 NLPAQDS 300
[118][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 55.5 bits (132), Expect = 2e-06
Identities = 28/63 (44%), Positives = 39/63 (61%), Gaps = 3/63 (4%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH---GFKTLHLYTLNLEKSALAILK 338
P+ AL P++ ++E V+ G L +MCK IL + G K LH+YTLNLEK A +L+
Sbjct: 237 PSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLLR 296
Query: 337 NLG 329
LG
Sbjct: 297 ELG 299
[119][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 55.1 bits (131), Expect = 3e-06
Identities = 27/61 (44%), Positives = 38/61 (62%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PA + AA+E D++EA++ + G ++C+ + A G LH YTLNLEK LAIL L
Sbjct: 266 PAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAGAPGLHFYTLNLEKVTLAILDALN 325
Query: 328 L 326
L
Sbjct: 326 L 326
[120][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 55.1 bits (131), Expect = 3e-06
Identities = 24/66 (36%), Positives = 41/66 (62%)
Frame = -1
Query: 490 ALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLGLIEETS 311
ALEP+K+++ V+ G L +MC+K++A G LH YT+NL ++ +L+ L L+ +
Sbjct: 239 ALEPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDVE 298
Query: 310 IPRTRP 293
P +P
Sbjct: 299 APLEKP 304
[121][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 54.7 bits (130), Expect = 4e-06
Identities = 30/86 (34%), Positives = 46/86 (53%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P E + ALEP+K+++ AV+ G L MC+K+LA+G LH YT+NL ++ +L+ L
Sbjct: 233 PQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQ 292
Query: 328 LIEETSIPRTRPANAIQAKEDGENQE 251
P Q+K G +E
Sbjct: 293 WAPSADRPLQHALPWKQSKGLGRREE 318
[122][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 54.7 bits (130), Expect = 4e-06
Identities = 28/67 (41%), Positives = 40/67 (59%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P I LE D+ ++++ +G + TEMC K+LA G LH YTLN + +L+I KNLG
Sbjct: 221 PRWIRKQLEAYGDDSDSIRKFGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSLSIWKNLG 280
Query: 328 LIEETSI 308
+ E I
Sbjct: 281 IGEREKI 287
[123][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 54.3 bits (129), Expect = 5e-06
Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL--AHGFKTLHLYTLNLEKSALAILKN 335
P + ALEP+K ++E V+ G L +MC+KIL G + LH YT+NLEK +L+
Sbjct: 194 PQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEKGTRMLLEE 253
Query: 334 LGLI 323
L L+
Sbjct: 254 LNLV 257
[124][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 53.9 bits (128), Expect = 6e-06
Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-AHGFKTLHLYTLNLEKSALAILKNL 332
P I+ LEPIK+++EA++ YG+ L MC+++L + +H+YTLN E + +L+ L
Sbjct: 254 PQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTLNREVATTELLQQL 313
Query: 331 GLIEETSIPRTRP----ANAIQAKED 266
GL R P AN + +ED
Sbjct: 314 GLWRPYQSHRLLPWKPSANLKRLQED 339
[125][TOP]
>UniRef100_UPI0001744B6A 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B6A
Length = 314
Score = 53.9 bits (128), Expect = 6e-06
Identities = 26/60 (43%), Positives = 35/60 (58%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
PA ++ AL ++ + AV G+H TE C ++L HG +HLYTLN L ILK LG
Sbjct: 237 PARLLKALMKVQHDPAAVLEVGLHHATEQCSELLHHGVSGIHLYTLNQAGPILEILKRLG 296
[126][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 53.9 bits (128), Expect = 6e-06
Identities = 27/61 (44%), Positives = 39/61 (63%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + LE D+ ++++A+G + TEMC+K+LA G LH YTLN + +LAI NLG
Sbjct: 221 PRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLG 280
Query: 328 L 326
L
Sbjct: 281 L 281
[127][TOP]
>UniRef100_C7MUK8 5,10-methylenetetrahydrofolate reductase n=1 Tax=Saccharomonospora
viridis DSM 43017 RepID=C7MUK8_SACVD
Length = 302
Score = 53.5 bits (127), Expect = 8e-06
Identities = 28/78 (35%), Positives = 44/78 (56%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + LEP+ D+ +A +A G+ + TE+C+++LA G LH YT N K+ ++ LG
Sbjct: 229 PRWLADRLEPLSDDPKAFRAEGLDVITELCERLLAEGVPELHFYTFNRSKATRELVDRLG 288
Query: 328 LIEETSIPRTRPANAIQA 275
L RT+P A Q+
Sbjct: 289 L----RSARTKPVLAAQS 302
[128][TOP]
>UniRef100_C6P2D6 Methylenetetrahydrofolate reductase n=1 Tax=Sideroxydans
lithotrophicus ES-1 RepID=C6P2D6_9GAMM
Length = 280
Score = 53.5 bits (127), Expect = 8e-06
Identities = 24/60 (40%), Positives = 40/60 (66%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNLG 329
P + +E D+ E+V+A+G+ + T++C+K++A G +LH YTLN ++L ILK LG
Sbjct: 219 PRWMRKTMEGYGDDSESVQAFGLDVVTQLCEKLIAGGAPSLHFYTLNQANASLEILKRLG 278
[129][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 53.5 bits (127), Expect = 8e-06
Identities = 36/94 (38%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKNL 332
P IM L+ IKDN+ A++ YG+ MC+++L G LH YTLN E + IL L
Sbjct: 220 PKSIMDDLQTIKDNDVAIRNYGVQKAINMCRELLDSGLVPGLHFYTLNREVATREILTAL 279
Query: 331 GL-IEETSIPRTRPANAIQAKEDGENQERPTEDM 233
GL + + R P A NQ+R TED+
Sbjct: 280 GLWCMDPAASRPLPWRA------SANQKRFTEDV 307
[130][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 53.5 bits (127), Expect = 8e-06
Identities = 26/59 (44%), Positives = 38/59 (64%)
Frame = -1
Query: 508 PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNL 332
P E M LEP+K+++ AV+ G L E+C+KILA G LH YT+NL ++ +L+ L
Sbjct: 233 PDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEEL 291