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[1][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 206 bits (523), Expect = 1e-51
Identities = 99/122 (81%), Positives = 109/122 (89%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EKL+EL+ LKE +TDLDRA+KGKPP K DGK+K+NL+ EA+EKKI+ TN KIEKM+
Sbjct: 739 LTEKLEELKGTLKEFKTDLDRAKKGKPPLKDADGKQKRNLTPEAIEKKIATTNQKIEKME 798
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP F
Sbjct: 799 LSMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPQF 858
Query: 214 RF 209
RF
Sbjct: 859 RF 860
[2][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 206 bits (523), Expect = 1e-51
Identities = 100/124 (80%), Positives = 115/124 (92%), Gaps = 2/124 (1%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPP--SKSPDGKKKKNLSSEALEKKISQTNAKIEK 401
LNEK++EL+AV++EL++DL R +KGKPP SK+ DGK K+NL+ E+LEKKI+QTNAKIEK
Sbjct: 787 LNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEK 846
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP 221
M+RD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP
Sbjct: 847 MERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP 906
Query: 220 DFRF 209
FRF
Sbjct: 907 SFRF 910
[3][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 205 bits (522), Expect = 2e-51
Identities = 99/122 (81%), Positives = 111/122 (90%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK++EL+A LKEL+TDLDRA+KGKPP K DGK+K+NLS E +EKKI+ TN +IEKM+
Sbjct: 770 LIEKIEELKATLKELKTDLDRAKKGKPPLKDADGKQKRNLSPENIEKKIASTNQRIEKME 829
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
+MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP F
Sbjct: 830 LNMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPQF 889
Query: 214 RF 209
RF
Sbjct: 890 RF 891
[4][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 204 bits (519), Expect = 4e-51
Identities = 96/122 (78%), Positives = 110/122 (90%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+ ++EL+TDL R +KGKPPSK DGK K+NL+ EALE+K++Q NAKIEKM+
Sbjct: 806 LNEKIDELKTAMEELKTDLSRVKKGKPPSKGADGKPKRNLNPEALERKMAQINAKIEKME 865
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDP F
Sbjct: 866 RDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSF 925
Query: 214 RF 209
RF
Sbjct: 926 RF 927
[5][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 203 bits (517), Expect = 7e-51
Identities = 97/122 (79%), Positives = 111/122 (90%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK++EL++ LKEL+TDLDRA+KGKPP K DGK+K++L+ EA+EKKI+ TN KIEKM+
Sbjct: 756 LTEKIEELKSTLKELKTDLDRAKKGKPPLKGADGKQKRSLTPEAIEKKIATTNQKIEKME 815
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI+KIFNKSLLAKFTWAMDVDP F
Sbjct: 816 MAMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAMDVDPQF 875
Query: 214 RF 209
RF
Sbjct: 876 RF 877
[6][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 202 bits (513), Expect = 2e-50
Identities = 98/122 (80%), Positives = 108/122 (88%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L+EK+ ELQ VL EL+TDL RA+KGKPP K DGK KKN++ E LE+KI+QTN KIEKM+
Sbjct: 762 LSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIAQTNTKIEKME 821
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDMKTKEDLKTVALGTSKINYLDPRI+VAWCKR EVPIEKIFNKSLLAKF WAMDVDP F
Sbjct: 822 RDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPSF 881
Query: 214 RF 209
RF
Sbjct: 882 RF 883
[7][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 202 bits (513), Expect = 2e-50
Identities = 98/122 (80%), Positives = 108/122 (88%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L+EK+ ELQ VL EL+TDL RA+KGKPP K DGK KKN++ E LE+KI+QTN KIEKM+
Sbjct: 668 LSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIAQTNTKIEKME 727
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDMKTKEDLKTVALGTSKINYLDPRI+VAWCKR EVPIEKIFNKSLLAKF WAMDVDP F
Sbjct: 728 RDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPSF 787
Query: 214 RF 209
RF
Sbjct: 788 RF 789
[8][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 201 bits (512), Expect = 3e-50
Identities = 95/122 (77%), Positives = 110/122 (90%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+ L+EL+TDL RA+KGKPP+K DG+ K+NL+ E+LE+KI+QTNAKIEKM+
Sbjct: 805 LNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEPKRNLNPESLERKIAQTNAKIEKME 864
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD KTKEDLK VAL TSKI+YLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDP F
Sbjct: 865 RDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSF 924
Query: 214 RF 209
RF
Sbjct: 925 RF 926
[9][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 201 bits (510), Expect = 4e-50
Identities = 96/122 (78%), Positives = 109/122 (89%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+ L+EL+TDL RA+KGKPPSK DG+ K+NL+ EALE+KI+QTNAKIEKM+
Sbjct: 805 LNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNPEALERKIAQTNAKIEKME 864
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD KTKEDLK VAL TSKI+YLDPRITVAWCKR EVPIEK+FNKSLLAKF WAMDVDP F
Sbjct: 865 RDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSF 924
Query: 214 RF 209
RF
Sbjct: 925 RF 926
[10][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 194 bits (494), Expect = 3e-48
Identities = 91/122 (74%), Positives = 110/122 (90%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L+EK+++L+ ++EL+TDL RA+KGKPP K DGK K+N++ EA+EKKI+QTN KIEKM+
Sbjct: 788 LDEKINKLKNFIEELKTDLSRAKKGKPPLKGSDGKTKRNMNPEAIEKKIAQTNVKIEKME 847
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD +TKEDLKTVALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF WAMDV+P F
Sbjct: 848 RDKETKEDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKMFNKSLLAKFAWAMDVEPSF 907
Query: 214 RF 209
RF
Sbjct: 908 RF 909
[11][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 194 bits (493), Expect = 4e-48
Identities = 92/122 (75%), Positives = 107/122 (87%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LN K+DEL+ +L L+TDL RA+KGKPP + DGK K+NL+ EALE+KI QTNAKIEKM+
Sbjct: 773 LNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTNAKIEKME 832
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD +TKE LKT+ALGTSKI+YLDPRITVAWCKRHEVPIEK+FNKSLLAKF W+MDVDP F
Sbjct: 833 RDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPSF 892
Query: 214 RF 209
RF
Sbjct: 893 RF 894
[12][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 183 bits (465), Expect(2) = 1e-47
Identities = 91/107 (85%), Positives = 98/107 (91%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DELQ VLKEL+ DLDRARKGK P+KS DGK K++L+ E LEKKISQTNAKIEKMQ
Sbjct: 766 LNEKIDELQDVLKELKVDLDRARKGKSPTKSSDGKSKRSLTPEVLEKKISQTNAKIEKMQ 825
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 254
RDMKTK DLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+F KSLL
Sbjct: 826 RDMKTKVDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKLFTKSLL 872
Score = 30.8 bits (68), Expect(2) = 1e-47
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = -3
Query: 279 KRFSTSLCWQSSLGLWMWTLTSDSEI 202
K F+ SL Q+ LG WMWT SDSEI
Sbjct: 865 KLFTKSLL-QNLLGQWMWTQISDSEI 889
[13][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 192 bits (487), Expect = 2e-47
Identities = 90/119 (75%), Positives = 105/119 (88%)
Frame = -2
Query: 565 KLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
K++EL+ +KEL DLDRA+KG+ P DGK+K+NL+ EALEKKI QT KIEKM+RDM
Sbjct: 793 KIEELREQIKELNIDLDRAKKGRTPLMGSDGKRKRNLTPEALEKKIMQTQGKIEKMERDM 852
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
+TKED+KTVALGTSKINY+DPRITVAWCKRH+VPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 853 QTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 911
[14][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 192 bits (487), Expect = 2e-47
Identities = 90/119 (75%), Positives = 105/119 (88%)
Frame = -2
Query: 565 KLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
K++EL+ +KEL DLDRA+KG+ P DGK+K+NL+ EALEKKI QT KIEKM+RDM
Sbjct: 108 KIEELREQIKELNIDLDRAKKGRTPLMGSDGKRKRNLTPEALEKKIMQTQGKIEKMERDM 167
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
+TKED+KTVALGTSKINY+DPRITVAWCKRH+VPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 168 QTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 226
[15][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 192 bits (487), Expect = 2e-47
Identities = 94/122 (77%), Positives = 107/122 (87%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+DE++ VL L+TDL RA+KGKPP K DGK++ NL+ EALE+KI+QTNAKIEKM+
Sbjct: 737 LTEKIDEMKGVLNGLKTDLARAKKGKPPLKDADGKRR-NLTPEALERKIAQTNAKIEKME 795
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RD TKEDLKTVALGTSKINYLDPRI+VAWCKR EVPIEK+FNKSLLAKF WAMDV PDF
Sbjct: 796 RDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMDVPPDF 855
Query: 214 RF 209
RF
Sbjct: 856 RF 857
[16][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 188 bits (477), Expect = 3e-46
Identities = 90/122 (73%), Positives = 106/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +++EL+ VLKEL+T+LDRA+KGKPP + DGKK ++L A EKKI+Q +AKIEKM+
Sbjct: 390 LTARIEELKEVLKELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKME 449
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KF WAMDV+P++
Sbjct: 450 RDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEY 509
Query: 214 RF 209
RF
Sbjct: 510 RF 511
[17][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 188 bits (477), Expect = 3e-46
Identities = 92/122 (75%), Positives = 101/122 (82%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+A EL+ DL + RKGK DGK K+NL+ EA EKKISQ KIEKM+
Sbjct: 795 LNEKIDELKAQRDELKADLSKVRKGKNLGNDKDGKPKRNLAPEAFEKKISQIETKIEKME 854
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
D K KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL+AKF+WAMDVDPDF
Sbjct: 855 MDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMDVDPDF 914
Query: 214 RF 209
RF
Sbjct: 915 RF 916
[18][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 188 bits (477), Expect = 3e-46
Identities = 90/122 (73%), Positives = 106/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +++EL+ VLKEL+T+LDRA+KGKPP + DGKK ++L A EKKI+Q +AKIEKM+
Sbjct: 272 LTARIEELKEVLKELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKME 331
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KF WAMDV+P++
Sbjct: 332 RDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEY 391
Query: 214 RF 209
RF
Sbjct: 392 RF 393
[19][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 188 bits (477), Expect = 3e-46
Identities = 90/122 (73%), Positives = 106/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +++EL+ VLKEL+T+LDRA+KGKPP + DGKK ++L A EKKI+Q +AKIEKM+
Sbjct: 146 LTARIEELKEVLKELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKME 205
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KF WAMDV+P++
Sbjct: 206 RDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEY 265
Query: 214 RF 209
RF
Sbjct: 266 RF 267
[20][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 188 bits (477), Expect = 3e-46
Identities = 92/122 (75%), Positives = 101/122 (82%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+A EL+ DL + RKGK DGK K+NL+ EA EKKISQ KIEKM+
Sbjct: 795 LNEKIDELKAQRDELKADLSKVRKGKNLGNDKDGKPKRNLAPEAFEKKISQIETKIEKME 854
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
D K KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL+AKF+WAMDVDPDF
Sbjct: 855 MDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMDVDPDF 914
Query: 214 RF 209
RF
Sbjct: 915 RF 916
[21][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 188 bits (477), Expect = 3e-46
Identities = 90/122 (73%), Positives = 106/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +++EL+ VLKEL+T+LDRA+KGKPP + DGKK ++L A EKKI+Q +AKIEKM+
Sbjct: 792 LTARIEELKEVLKELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKME 851
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
RDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KF WAMDV+P++
Sbjct: 852 RDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEY 911
Query: 214 RF 209
RF
Sbjct: 912 RF 913
[22][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 187 bits (475), Expect = 5e-46
Identities = 88/122 (72%), Positives = 105/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL++ ++EL+ DL +A+KGKP +GK+K+NL+ EA+EKKI+ KI+KM+
Sbjct: 800 LNEKIDELKSQMEELKADLSKAKKGKPLGYDKEGKQKRNLAPEAIEKKIAMVEGKIDKME 859
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
D K KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL+AKF WAMDVDPDF
Sbjct: 860 MDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFGWAMDVDPDF 919
Query: 214 RF 209
RF
Sbjct: 920 RF 921
[23][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 186 bits (473), Expect = 8e-46
Identities = 94/125 (75%), Positives = 107/125 (85%), Gaps = 3/125 (2%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEA---LEKKISQTNAKIE 404
L EK+DE++ VL L+TDL RA+KGKPP K DGK++ NL+ EA LE+KI+QTNAKIE
Sbjct: 1326 LTEKIDEMKGVLNGLKTDLARAKKGKPPLKDADGKRR-NLTPEATYRLERKIAQTNAKIE 1384
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVD 224
KM+RD TKEDLKTVALGTSKINYLDPRI+VAWCKR EVPIEK+FNKSLLAKF WAMDV
Sbjct: 1385 KMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMDVP 1444
Query: 223 PDFRF 209
PDFRF
Sbjct: 1445 PDFRF 1449
[24][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 185 bits (470), Expect = 2e-45
Identities = 88/122 (72%), Positives = 104/122 (85%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+ EL+ L+EL TDLDRA+KGKPP K +GK K+N + EALEKKI+ T KI+KM+
Sbjct: 511 LEGKMQELEEQLEELETDLDRAKKGKPPLKDSEGKVKRNQTPEALEKKIAATKQKIDKMR 570
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
DM+ K+DLKTVALGTSKINY+DPRITVAWCKRHEVPIEKIFNKSLL+KF WAM+V+PDF
Sbjct: 571 LDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKIFNKSLLSKFAWAMEVEPDF 630
Query: 214 RF 209
RF
Sbjct: 631 RF 632
[25][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 184 bits (467), Expect = 4e-45
Identities = 87/122 (71%), Positives = 104/122 (85%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+ EL+ L+EL TDLDRA++GKPP K +GK K+N + EALEKKI+ T KI+KM+
Sbjct: 381 LELKMQELEEQLEELETDLDRAKRGKPPLKDSEGKVKRNQTPEALEKKIASTTQKIDKMR 440
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
DM+ K+DLKTVALGTSKINY+DPRITVAWCKRHEVPIEKIFNKSLL+KF WAM+V+PDF
Sbjct: 441 LDMRVKDDLKTVALGTSKINYMDPRITVAWCKRHEVPIEKIFNKSLLSKFAWAMEVEPDF 500
Query: 214 RF 209
RF
Sbjct: 501 RF 502
[26][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 184 bits (466), Expect = 5e-45
Identities = 85/122 (69%), Positives = 105/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+NEK+DEL++ ++EL+ DL++A+KGKP +GK K+NL+ EA++KK++ KIEKM+
Sbjct: 783 MNEKIDELKSQMEELKADLNKAKKGKPLGYDSEGKPKRNLAPEAIQKKVATLEGKIEKME 842
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
D + KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAMDVDP+F
Sbjct: 843 MDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMDVDPEF 902
Query: 214 RF 209
RF
Sbjct: 903 RF 904
[27][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 184 bits (466), Expect = 5e-45
Identities = 85/122 (69%), Positives = 105/122 (86%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+NEK+DEL++ ++EL+ DL++A+KGKP +GK K+NL+ EA++KK++ KIEKM+
Sbjct: 453 MNEKIDELKSQMEELKADLNKAKKGKPLGYDSEGKPKRNLAPEAIQKKVATLEGKIEKME 512
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
D + KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF WAMDVDP+F
Sbjct: 513 MDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMDVDPEF 572
Query: 214 RF 209
RF
Sbjct: 573 RF 574
[28][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 175 bits (443), Expect = 3e-42
Identities = 91/144 (63%), Positives = 106/144 (73%), Gaps = 22/144 (15%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSE----------------- 446
LNEK++EL+ +LKEL+ DL R KGKPP K+ DGK K+NL+ +
Sbjct: 647 LNEKIEELKGLLKELQEDLTRVNKGKPPLKNSDGKPKRNLNLKRYKGKLLKLIQKLRKWS 706
Query: 445 -----ALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 281
++ KKI+QTN KIEKM+RD +TKEDLKTVALGTSKINYLDPRITVAWCKRH+VPI
Sbjct: 707 ETRRLSVTKKIAQTNTKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPI 766
Query: 280 EKIFNKSLLAKFTWAMDVDPDFRF 209
EKIFNKSLLAKF WAMDV FRF
Sbjct: 767 EKIFNKSLLAKFAWAMDVVLIFRF 790
[29][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 144 bits (364), Expect = 4e-33
Identities = 67/97 (69%), Positives = 83/97 (85%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNEK+DEL+A+L+E + DL RA+KGKPP K DGK K+NL+ EAL+KKI QTN KIE ++
Sbjct: 756 LNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKIENIE 815
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 284
+ ++TKE+LKTVALGTSKINYLDPRITVAWC+RH P
Sbjct: 816 KQIETKEELKTVALGTSKINYLDPRITVAWCERHRFP 852
[30][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 138 bits (347), Expect = 3e-31
Identities = 71/122 (58%), Positives = 85/122 (69%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ EKL + L EL +L A+KGK +K + + AL KI + I K++
Sbjct: 465 IQEKLAGMNKELAELEDELRAAQKGKAENKKANKCGAPTILPWALNSKIDKKKQAIAKVE 524
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
++KEDLKTVALGTSKINY+DPRITVAWCKR+EVPIEKIFNKSLLAKF WAMDVDP F
Sbjct: 525 LQARSKEDLKTVALGTSKINYMDPRITVAWCKRNEVPIEKIFNKSLLAKFNWAMDVDPTF 584
Query: 214 RF 209
RF
Sbjct: 585 RF 586
[31][TOP]
>UniRef100_B3H4K2 Uncharacterized protein At4g26701.1 n=1 Tax=Arabidopsis thaliana
RepID=B3H4K2_ARATH
Length = 69
Score = 127 bits (320), Expect = 5e-28
Identities = 59/68 (86%), Positives = 63/68 (92%)
Frame = -2
Query: 412 KIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
KIEKM+RDM+TKEDLKTVALGTSKINY+DPRITVAWCKRHE PIEKIFNKSLL KF WAM
Sbjct: 2 KIEKMERDMQTKEDLKTVALGTSKINYMDPRITVAWCKRHEAPIEKIFNKSLLEKFAWAM 61
Query: 232 DVDPDFRF 209
DV+P F F
Sbjct: 62 DVEPHFTF 69
[32][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 117 bits (293), Expect = 6e-25
Identities = 61/123 (49%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARK---GKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKM 398
E + +LK+ + DL + K K P K + ++ E + KKI N KI KM
Sbjct: 464 ENITAKVGMLKKQKKDLKKILKLLTAGEADKIPTKKSPQTMTDEQVVKKIEAWNGKISKM 523
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPD 218
+ D+K K+D K V+LGTSKINY+DPRI+VAWCKR+EVPIEKIF+K+L KF WAM V PD
Sbjct: 524 EMDLKHKDDNKEVSLGTSKINYMDPRISVAWCKRNEVPIEKIFSKTLRDKFNWAMAVVPD 583
Query: 217 FRF 209
+ F
Sbjct: 584 WEF 586
[33][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 111 bits (278), Expect = 3e-23
Identities = 55/122 (45%), Positives = 84/122 (68%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LN++ L+ +LK + + D+ K + +K + E + K+I+ + KI+KM+
Sbjct: 407 LNDQKKALKKILKVIMENSDKKIPMKEDATKAGHLWEKKPTKEQVTKRITAWSEKIKKME 466
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
++K K+D K V+LGTSK+NY+DPRI+VAWCKR+EVPIEKIF+K++ KF WAM V PD+
Sbjct: 467 LNIKHKDDNKEVSLGTSKLNYMDPRISVAWCKRNEVPIEKIFSKTMRDKFNWAMAVTPDW 526
Query: 214 RF 209
+F
Sbjct: 527 QF 528
[34][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 107 bits (268), Expect = 5e-22
Identities = 50/88 (56%), Positives = 67/88 (76%)
Frame = -2
Query: 472 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRH 293
K K+N+ E+ +KK+ K+E ++ MK ++D KT+ALGTSKINY+DPRITVA+CK+
Sbjct: 799 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 858
Query: 292 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
E+PIEKIFN+SL KF WAM V +FRF
Sbjct: 859 EIPIEKIFNRSLRLKFPWAMFVTKNFRF 886
[35][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
RepID=B3L6G4_PLAKH
Length = 924
Score = 107 bits (268), Expect = 5e-22
Identities = 50/88 (56%), Positives = 67/88 (76%)
Frame = -2
Query: 472 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRH 293
K K+N+ E+ +KK+ K+E+++ MK ++D KT+ALGTSKINY+DPRITVA+CKR
Sbjct: 837 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 896
Query: 292 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 897 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 924
[36][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax RepID=A5KB33_PLAVI
Length = 931
Score = 107 bits (268), Expect = 5e-22
Identities = 50/88 (56%), Positives = 67/88 (76%)
Frame = -2
Query: 472 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRH 293
K K+N+ E+ +KK+ K+E+++ MK ++D KT+ALGTSKINY+DPRITVA+CKR
Sbjct: 844 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 903
Query: 292 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 904 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 931
[37][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 107 bits (266), Expect = 9e-22
Identities = 55/121 (45%), Positives = 79/121 (65%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
N + E +A ++ +D+ + + K+ K+KN S KIS ++ K++
Sbjct: 571 NHQKGESKAHGAQMEKLVDKKKAMEKELKALRQDKEKNKS------KISTMKERLAKLEL 624
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFR 212
MK KEDLKTV+LGTSKINYLDPRIT+AWCKR+EVP +F ++L+ KF W+M+V+PDF
Sbjct: 625 QMKMKEDLKTVSLGTSKINYLDPRITIAWCKRNEVPPPTVFTRALVEKFNWSMEVEPDFD 684
Query: 211 F 209
F
Sbjct: 685 F 685
[38][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 106 bits (265), Expect = 1e-21
Identities = 55/126 (43%), Positives = 79/126 (62%), Gaps = 5/126 (3%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDG-----KKKKNLSSEALEKKISQTNAKI 407
NE + E + L+ L+ + D+ + DG K K+N+ E+ +KK+ K+
Sbjct: 714 NEDIKEYKKYLQHLKKNSDKKFIFVSKVSTLDGTLRPNKVKENMKEESCKKKLITLIKKV 773
Query: 406 EKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
E + MK ++D KT+ALGTSKINY+DPRITVA+CK+ E+PIEK+FN+SL KF WAM
Sbjct: 774 ELLNNQMKVRDDNKTIALGTSKINYMDPRITVAFCKKFEIPIEKVFNRSLRLKFPWAMFA 833
Query: 226 DPDFRF 209
+F F
Sbjct: 834 TKNFTF 839
[39][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 105 bits (261), Expect = 3e-21
Identities = 48/86 (55%), Positives = 63/86 (73%)
Frame = -2
Query: 466 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEV 287
KKN + +KK++ + K+ M+ KE+LKTV+LGTSKINYLDPRIT++WCKRHEV
Sbjct: 674 KKNKDDKNQKKKLTALKERAAKLAIQMEMKEELKTVSLGTSKINYLDPRITLSWCKRHEV 733
Query: 286 PIEKIFNKSLLAKFTWAMDVDPDFRF 209
P +F K+L+ KF WAMD D DF+F
Sbjct: 734 PPPTVFTKALIDKFHWAMDCDMDFKF 759
[40][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 104 bits (259), Expect = 6e-21
Identities = 61/135 (45%), Positives = 83/135 (61%), Gaps = 13/135 (9%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSS-----EALEKKISQTN-- 416
L E + EL K L+++ K + +K +G +K ++ EA + K+S N
Sbjct: 869 LKEDIQELNEYCKHLQSNSKGEFKFESKTKDVNGNPRKLITKPGMKLEAAKNKLSTLNYL 928
Query: 415 --AKIEKMQRD----MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 254
A ++K Q+D M K+ KTVALGTSKINY+DPRITVA+CK++E+PIEK+FNKSL
Sbjct: 929 CFAPLKKKQKDHAIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKVFNKSLR 988
Query: 253 AKFTWAMDVDPDFRF 209
KF WAM V DF F
Sbjct: 989 MKFPWAMYVRSDFTF 1003
[41][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 103 bits (257), Expect = 9e-21
Identities = 53/119 (44%), Positives = 79/119 (66%), Gaps = 4/119 (3%)
Frame = -2
Query: 553 LQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEKMQRDMK 383
LQ +++ + ++ ARK +K D + SS+ +EKK + + +++K+Q
Sbjct: 78 LQEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSSKLVEKKQKAVQRLCDQLKKLQLQET 137
Query: 382 TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+E+ K +ALGTSK+NYLDPRITVAWCK+H+VPIEKIFNK+ KF WA+D+ D F+F
Sbjct: 138 DREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKIFNKTHREKFAWAIDMTDESFQF 196
[42][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 103 bits (257), Expect = 9e-21
Identities = 53/119 (44%), Positives = 79/119 (66%), Gaps = 4/119 (3%)
Frame = -2
Query: 553 LQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEKMQRDMK 383
LQ +++ + ++ ARK +K D + SS+ +EKK + + +++K+Q
Sbjct: 482 LQEKIQKKKEQIEEARKELKEAKQVDKDTPSDKSSKLVEKKQKAVQRLCDQLKKLQLQET 541
Query: 382 TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+E+ K +ALGTSK+NYLDPRITVAWCK+H+VPIEKIFNK+ KF WA+D+ D F+F
Sbjct: 542 DREENKVIALGTSKLNYLDPRITVAWCKKHQVPIEKIFNKTHREKFAWAIDMTDESFQF 600
[43][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 103 bits (257), Expect = 9e-21
Identities = 57/127 (44%), Positives = 79/127 (62%), Gaps = 5/127 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKK-----NLSSEALEKKISQTNAK 410
++E++ ELQA +K L ++ + + + G +K + EA +KK+ +
Sbjct: 575 ISEEIAELQAYMKYLESNQTKPFTFESRTVDAKGNPRKAATRQGMKLEACQKKLETAMKR 634
Query: 409 IEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
+ M+ K+D KTVALGTSKINY+DPRITVA+CKR+EVPIEKIFNKSL KF WAM
Sbjct: 635 SKVHAIKMRIKDDNKTVALGTSKINYMDPRITVAFCKRYEVPIEKIFNKSLRTKFPWAMY 694
Query: 229 VDPDFRF 209
D+ F
Sbjct: 695 AGADYIF 701
[44][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 103 bits (256), Expect = 1e-20
Identities = 56/127 (44%), Positives = 81/127 (63%), Gaps = 5/127 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTN-AKIEKM 398
L E + EL K L+++ K + +K +G +K ++ ++ + ++ A ++K
Sbjct: 873 LKEDIQELNEYCKHLQSNSKDEFKFESKTKDVNGNPRKLITKPGMKLEAAKNKLATLKKK 932
Query: 397 QRD----MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
Q+D M K+ KTVALGTSKINY+DPRITVA+CK++E+PIEK+FNKSL KF WAM
Sbjct: 933 QKDHNIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEIPIEKVFNKSLRMKFPWAMC 992
Query: 229 VDPDFRF 209
V DF F
Sbjct: 993 VRSDFTF 999
[45][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 100 bits (249), Expect = 8e-20
Identities = 57/131 (43%), Positives = 79/131 (60%), Gaps = 9/131 (6%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD----GKKKK-----NLSSEALEKKISQ 422
L E L +A LK L+ + P S + GK++K N S + ++KKI
Sbjct: 511 LEEDLKICEAFLKILKKNNKSVTMNDLPKLSTEVSFNGKQRKYPINLNSSLDVVQKKIDS 570
Query: 421 TNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFT 242
+KI + +K K+D KTVAL TSKINY+DPRI+VA+CK++++PI+KIFN+SL KF
Sbjct: 571 IKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKIFNRSLRTKFP 630
Query: 241 WAMDVDPDFRF 209
WAM DF F
Sbjct: 631 WAMYTRSDFSF 641
[46][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 99.8 bits (247), Expect = 1e-19
Identities = 57/131 (43%), Positives = 79/131 (60%), Gaps = 9/131 (6%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD----GKKKK-----NLSSEALEKKISQ 422
L E L +A LK L+ + P S + GK++K N S + ++KKI
Sbjct: 523 LEEDLKICEAFLKILKKNNKSVTISDLPKLSTEVSFNGKQRKYPINLNSSLDVVQKKIDS 582
Query: 421 TNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFT 242
+KI + +K K+D KTVAL TSKINY+DPRI+VA+CK++++PI+KIFN+SL KF
Sbjct: 583 IKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRISVAFCKKYDLPIDKIFNRSLRTKFP 642
Query: 241 WAMDVDPDFRF 209
WAM DF F
Sbjct: 643 WAMYTRSDFSF 653
[47][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 98.6 bits (244), Expect = 3e-19
Identities = 50/101 (49%), Positives = 66/101 (65%)
Frame = -2
Query: 511 ARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINY 332
A K K +K KKK + +KK++ + K+ M KE+LKTV+LGTSKINY
Sbjct: 380 AEKKKDLAKQVAEMKKKT-DDKNQKKKLAALKERQSKLAIQMNMKEELKTVSLGTSKINY 438
Query: 331 LDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
LDPRIT++WCKRHEVP +F K+L+ KF WAMD + +F F
Sbjct: 439 LDPRITLSWCKRHEVPPNVVFTKALIDKFHWAMDCEMEFSF 479
[48][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 98.2 bits (243), Expect = 4e-19
Identities = 56/123 (45%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L E T+L RA+ K D K K NL E +K + + ++ K+
Sbjct: 571 LQAKIDAKKEQLDEAVTELKRAKADHKAKK--DIKSKSNL--EKKKKLLQKIEEQLMKLS 626
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
KE+ K +ALGTSK+NYLDPRI+VAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 627 VQATDKEENKQIALGTSKLNYLDPRISVAWCKKFGVPIEKIYNKTQREKFAWAIDMADED 686
Query: 217 FRF 209
F F
Sbjct: 687 FEF 689
[49][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 97.1 bits (240), Expect = 9e-19
Identities = 51/135 (37%), Positives = 81/135 (60%), Gaps = 13/135 (9%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPS--------KSPDGKKKKNL-----SSEALEK 434
+ ++++ + KEL T L++ +K + + DGK K + + E +++
Sbjct: 579 MEQRINVYKDYEKELHTHLNKCKKNGVNAYEKEVILEEKDDGKHKMFVKKFPGTKEKIQE 638
Query: 433 KISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 254
I + KI++ Q ++KE K +ALGTSK NY DPRI+V WCK+ EVP+EK+F K+L+
Sbjct: 639 AIEKIKKKIDEEQNKKQSKEKNKEIALGTSKTNYNDPRISVVWCKKWEVPVEKVFPKTLI 698
Query: 253 AKFTWAMDVDPDFRF 209
AKF WAMD D ++ F
Sbjct: 699 AKFVWAMDTDLEWSF 713
[50][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 96.7 bits (239), Expect = 1e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 649 LQSKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 764
Query: 217 FRF 209
+ F
Sbjct: 765 YEF 767
[51][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 96.7 bits (239), Expect = 1e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 442 LQSKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 497
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 498 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 557
Query: 217 FRF 209
+ F
Sbjct: 558 YEF 560
[52][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 96.7 bits (239), Expect = 1e-18
Identities = 47/95 (49%), Positives = 68/95 (71%), Gaps = 5/95 (5%)
Frame = -2
Query: 478 DGKKKK---NLSS--EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRIT 314
+GK +K NLSS E ++KK+ K+ ++ +K K+D KTV+L TSK+NY+DPRI+
Sbjct: 566 NGKPRKFPINLSSNSEIIQKKLDSIKTKLSNLELKIKIKDDNKTVSLNTSKLNYMDPRIS 625
Query: 313 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
VA+CK++E+PI+K+FN+SL KF WAM DF F
Sbjct: 626 VAFCKKYELPIDKVFNRSLRTKFPWAMYTRSDFSF 660
[53][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 96.7 bits (239), Expect = 1e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 649 LQSKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 764
Query: 217 FRF 209
+ F
Sbjct: 765 YEF 767
[54][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus caballus
RepID=UPI0001797824
Length = 765
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 647 LQSKIDAKKEQLADARRDLKSAKADAKVLK--DAKTKKVVESK--KKAVQRLEEQLMKLE 702
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 703 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 762
Query: 217 FRF 209
+ F
Sbjct: 763 YEF 765
[55][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 886 LQSKIDAKKEQLADARRDLKSAKADAKVLK--DAKTKKVVESK--KKAVQRLEEQLMKLE 941
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 942 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 1001
Query: 217 FRF 209
+ F
Sbjct: 1002 YEF 1004
[56][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 640 LQSKIDAKKDQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 695
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 696 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDED 755
Query: 217 FRF 209
+ F
Sbjct: 756 YEF 758
[57][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 634 LQSKIDAKKEQLADARRDLKSAKADAKVLK--DAKTKKVVESK--KKAVQRLEEQLMKLE 689
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 690 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 749
Query: 217 FRF 209
+ F
Sbjct: 750 YEF 752
[58][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 651 LQSKIDAKKEQLADARRDLKSAKADAKVLK--DAKTKKVVESK--KKAVQRLEEQLMKLE 706
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 707 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 766
Query: 217 FRF 209
+ F
Sbjct: 767 YEF 769
[59][TOP]
>UniRef100_Q3TSR2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3TSR2_MOUSE
Length = 144
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 26 LQSKIDAKKDQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 81
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 82 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDED 141
Query: 217 FRF 209
+ F
Sbjct: 142 YEF 144
[60][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 96.3 bits (238), Expect = 2e-18
Identities = 40/75 (53%), Positives = 58/75 (77%)
Frame = -2
Query: 433 KISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 254
KI ++ K++ MK K++LK+V+LGTSKINY+DPRIT+AWCK ++VP ++ K+L+
Sbjct: 561 KIRTLKERLSKLELQMKMKDELKSVSLGTSKINYMDPRITIAWCKHNDVPPPTVYTKALV 620
Query: 253 AKFTWAMDVDPDFRF 209
KF WAM+V+PDF F
Sbjct: 621 EKFNWAMEVEPDFDF 635
[61][TOP]
>UniRef100_Q9BVT2 Putative uncharacterized protein (Fragment) n=1 Tax=Homo sapiens
RepID=Q9BVT2_HUMAN
Length = 176
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 58 LQTKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 113
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 114 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 173
Query: 217 FRF 209
+ F
Sbjct: 174 YEF 176
[62][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 647 LQTKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 702
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 703 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 762
Query: 217 FRF 209
+ F
Sbjct: 763 YEF 765
[63][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 649 LQSKIDAKKDQLADARKDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDED 764
Query: 217 FRF 209
+ F
Sbjct: 765 YEF 767
[64][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 649 LQSKIDAKKDQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDED 764
Query: 217 FRF 209
+ F
Sbjct: 765 YEF 767
[65][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 647 LQTKIDAKKEQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 702
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 703 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 762
Query: 217 FRF 209
+ F
Sbjct: 763 YEF 765
[66][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 649 LQSKIDAKKDQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLE 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDED 764
Query: 217 FRF 209
+ F
Sbjct: 765 YEF 767
[67][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 95.9 bits (237), Expect = 2e-18
Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 630 LQTKIDAKKEQLADARRDLKSAKADAKVLK--DAKTKKVVESK--KKAVQRLEEQLMKLE 685
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D
Sbjct: 686 VQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADED 745
Query: 217 FRF 209
+ F
Sbjct: 746 YEF 748
[68][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 95.9 bits (237), Expect = 2e-18
Identities = 55/131 (41%), Positives = 83/131 (63%), Gaps = 10/131 (7%)
Frame = -2
Query: 571 NEKLD------ELQAVLKE----LRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQ 422
NEKL+ + ++VLKE + + +R + + K+ K+ +E LE+ I +
Sbjct: 736 NEKLEAEGKDKQKKSVLKERIEAIEEEFERLAQERGTGKAT---LKRERPTEKLEEMIEK 792
Query: 421 TNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFT 242
+ +I+ + M +++ K VALGTSKINYLDPRITVAW ++VPIEK+F+K+LL KF
Sbjct: 793 LDDRIKTFKLQMIDRDEGKEVALGTSKINYLDPRITVAWASANKVPIEKMFSKTLLEKFP 852
Query: 241 WAMDVDPDFRF 209
WAM VD D++F
Sbjct: 853 WAMGVDDDWKF 863
[69][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 95.1 bits (235), Expect = 3e-18
Identities = 53/123 (43%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 455 LQTKIDEKQKQLSAARKQLKAAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 510
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 511 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 570
Query: 217 FRF 209
F F
Sbjct: 571 FEF 573
[70][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 95.1 bits (235), Expect = 3e-18
Identities = 53/123 (43%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 649 LQTKIDEKQKQLSAARKQLKAAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 764
Query: 217 FRF 209
F F
Sbjct: 765 FEF 767
[71][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 95.1 bits (235), Expect = 3e-18
Identities = 53/123 (43%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 649 LQTKIDEKQKQLSAARKQLKAAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 704
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 705 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 764
Query: 217 FRF 209
F F
Sbjct: 765 FEF 767
[72][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 94.7 bits (234), Expect = 4e-18
Identities = 53/123 (43%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 652 LQTKIDEKQKQLSAARKQLKGAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 707
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 708 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 767
Query: 217 FRF 209
F F
Sbjct: 768 FEF 770
[73][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 94.7 bits (234), Expect = 4e-18
Identities = 53/120 (44%), Positives = 74/120 (61%), Gaps = 1/120 (0%)
Frame = -2
Query: 565 KLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
K+D + L + R DL A+ K D K KK +S + +++ + K+E D
Sbjct: 646 KIDAKKDQLADARKDLKSAKADAKVMK--DAKTKKVVSKKKAVQRLEEQLMKLEVQATD- 702
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 703 --REENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 760
[74][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment) n=1
Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 94.7 bits (234), Expect = 4e-18
Identities = 53/123 (43%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 665 LQTKIDEKQKQLSAARKQLKGAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 720
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 721 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 780
Query: 217 FRF 209
F F
Sbjct: 781 FEF 783
[75][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 94.7 bits (234), Expect = 4e-18
Identities = 49/123 (39%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+ + L E ++ RK + G K+ L+++ K++ + +++K++
Sbjct: 926 LKEKIRAKRDALDECESEYHDLRKA-----AKRGSVKEKLNADKKGKQLERLKDQLKKLE 980
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+++ KT+ALGTSK+NYLDPRITVAWCK++ VPIEKIFNK+ KF WA+ + D +
Sbjct: 981 LQETDRDENKTIALGTSKLNYLDPRITVAWCKKYGVPIEKIFNKTHRTKFLWAIHMADEN 1040
Query: 217 FRF 209
+RF
Sbjct: 1041 YRF 1043
[76][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 94.4 bits (233), Expect = 6e-18
Identities = 52/126 (41%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+D + L++ + +L+ A K K +K+ +KK E L++++++ N +
Sbjct: 475 LQTKIDAKKEQLEKAQQELEEAEDEFKDKKDAKAAGNVQKKKKLLERLKEQLAKLNVQAT 534
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K +ALGTSK+NYLDPRI++AWCK+ VPIEKIFNK+ KF WA+D+
Sbjct: 535 D-------KEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKIFNKTQREKFAWAIDMT 587
Query: 226 DPDFRF 209
D DF F
Sbjct: 588 DEDFEF 593
[77][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 94.4 bits (233), Expect = 6e-18
Identities = 53/119 (44%), Positives = 76/119 (63%), Gaps = 3/119 (2%)
Frame = -2
Query: 556 ELQAVLK---ELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
EL+ LK EL+ LD K K K G+ S E LEK++++ N +I M+ M
Sbjct: 703 ELEVRLKAADELKKALDAELKSK---KVDPGRS----SMEQLEKRLNKLNERINVMRTQM 755
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
K++ KT ALGTSKINY+DPR+T ++ KR +VPIEK+F+K++ KF WA D PD+++
Sbjct: 756 IDKDENKTTALGTSKINYIDPRLTYSFSKREDVPIEKLFSKTIRDKFNWAADTPPDWKW 814
[78][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 94.0 bits (232), Expect = 7e-18
Identities = 52/126 (41%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+D + L++ + +L+ A K K +K+ +KK E L++++++ N +
Sbjct: 475 LQTKIDAKKEQLEKAQQELEEAEDEFKDKKDAKAEANVQKKKKLLERLKEQLAKLNVQAT 534
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K +ALGTSK+NYLDPRI++AWCK+ VPIEKIFNK+ KF WA+D+
Sbjct: 535 D-------KEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKIFNKTQREKFAWAIDMT 587
Query: 226 DPDFRF 209
D DF F
Sbjct: 588 DEDFEF 593
[79][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 94.0 bits (232), Expect = 7e-18
Identities = 57/124 (45%), Positives = 78/124 (62%), Gaps = 4/124 (3%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE---KM 398
E+L +L + + D D+ + K S +K+ + + KI + AK E K
Sbjct: 771 ERLPKLIQLAITNKKDKDKEKTDKEISFDVKAAFEKSRTLPDAKGKIKEKIAKYEEQIKK 830
Query: 397 QRDMKT-KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDP 221
Q +KT K++LKTVALGTSKINYLDPRITVAWCK+++VP++KIF KSL KF W+ DV
Sbjct: 831 QEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPVDKIFTKSLRDKFPWS-DVGT 889
Query: 220 DFRF 209
D+ F
Sbjct: 890 DYIF 893
[80][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 93.6 bits (231), Expect = 1e-17
Identities = 47/116 (40%), Positives = 70/116 (60%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+ +A +KE + +A++ DG E +K + + ++ K++
Sbjct: 630 LKEKIQTKRAAVKEAKEQYKQAKRDVK-----DGSVHSKTQLEKRKKALERLKEQLTKLE 684
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
KE+ KT+ALGTSK+NYLDPRI+VAWCK+ VPIEKI+NK+ KF WA+D+
Sbjct: 685 VQETDKEENKTIALGTSKLNYLDPRISVAWCKKFNVPIEKIYNKTQRDKFRWAIDM 740
[81][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 93.6 bits (231), Expect = 1e-17
Identities = 51/125 (40%), Positives = 78/125 (62%), Gaps = 4/125 (3%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
+++++ LQ + + D+ A+KG KS + A+EKK Q +E++ +
Sbjct: 316 DKQMENLQEKIDKKHLDIKEAKKGLKAIKSEYKNSRNEKLKLAMEKKAKQVERLVEQLAK 375
Query: 391 -DMKT--KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-D 224
+MK KE+ K +ALGTSK+NYLDPRI+VAW K+ +VPIEK++NK+ KF WA+D+
Sbjct: 376 LEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKVYNKTQRDKFRWAVDMAG 435
Query: 223 PDFRF 209
DF F
Sbjct: 436 ADFVF 440
[82][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 93.6 bits (231), Expect = 1e-17
Identities = 51/125 (40%), Positives = 78/125 (62%), Gaps = 4/125 (3%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
+++++ LQ + + D+ A+KG KS + A+EKK Q +E++ +
Sbjct: 755 DKQMENLQEKIDKKHLDIKEAKKGLKAIKSEYKNSRNEKLKLAMEKKAKQVERLVEQLAK 814
Query: 391 -DMKT--KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-D 224
+MK KE+ K +ALGTSK+NYLDPRI+VAW K+ +VPIEK++NK+ KF WA+D+
Sbjct: 815 LEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEKVYNKTQRDKFRWAVDMAG 874
Query: 223 PDFRF 209
DF F
Sbjct: 875 ADFVF 879
[83][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 93.2 bits (230), Expect = 1e-17
Identities = 50/123 (40%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K++ + + E++ ++ A++ + KKKK L ++ + K+E +
Sbjct: 850 LKAKIEAKREQINEIKKEVKNAKRNG--DSGTEAKKKKQLD------RLKEQLLKLEVQE 901
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
D KE+ KT+ALGTSK+NYLDPRI+VAWCK++ VPIEKI+NK+ KF WA+D+ PD
Sbjct: 902 TD---KEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPD 958
Query: 217 FRF 209
+ F
Sbjct: 959 YVF 961
[84][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 93.2 bits (230), Expect = 1e-17
Identities = 46/119 (38%), Positives = 75/119 (63%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+NEK+++ Q +++ + + A+ +KS + K + E +KK+ + ++ K++
Sbjct: 364 MNEKIEKKQRDIQDAKQETKSAKSDYKHNKS----EAKRKAYEGKKKKVERLQEQLIKLE 419
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPD 218
KE+ K +ALGTSK+NYLDPRITVAWCK++ VPIEK +NK+ KF WA+ + D
Sbjct: 420 VQATDKEENKEIALGTSKLNYLDPRITVAWCKKYSVPIEKCYNKTQRDKFAWAIAMVDD 478
[85][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 92.8 bits (229), Expect = 2e-17
Identities = 50/123 (40%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
++EK +L A K+L+ A K + + D KK + E K + + ++ K+Q
Sbjct: 676 IDEKQKQLSAARKQLK-----AAKAEHKASHDDKSKK---AVEVKRKAVQRIEEQLMKLQ 727
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 728 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 787
Query: 217 FRF 209
F F
Sbjct: 788 FEF 790
[86][TOP]
>UniRef100_Q6LBJ1 Topoisomerase I (Fragment) n=1 Tax=Mus musculus RepID=Q6LBJ1_MOUSE
Length = 115
Score = 92.8 bits (229), Expect = 2e-17
Identities = 51/119 (42%), Positives = 74/119 (62%), Gaps = 1/119 (0%)
Frame = -2
Query: 562 LDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMK 383
+D + L + R DL A+ K D K KK + S+ +K + + ++ K++
Sbjct: 1 IDAKKDQLADARRDLKSAKADAKVMK--DAKTKKVVESK--KKAVQRLEEQLMKLEVQAT 56
Query: 382 TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+E+ K +ALGTSK+NYLDPRITVAWCK+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 57 DREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 115
[87][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 92.8 bits (229), Expect = 2e-17
Identities = 47/116 (40%), Positives = 70/116 (60%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+++ + LKE + + RA+ K KK E +KK N ++ K+
Sbjct: 442 LREKIEKKEQQLKEAKKEEKRAKSDLKERKDESSKKLY----EKRKKKTEMLNRQLHKLN 497
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
K + K VAL TSK+NY+DPRI+VAWCK++EVP+EK+FNK+ KF WA+++
Sbjct: 498 LTETDKVENKEVALSTSKLNYMDPRISVAWCKKNEVPVEKVFNKTQREKFKWAIEM 553
[88][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 92.4 bits (228), Expect = 2e-17
Identities = 49/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+D + ++E + ++ +A +K K L+ E +K + + ++ KM
Sbjct: 544 LQEKIDAKKKQVEEAQEEVKKAEDEFKDTKDA----KAELNVEKKKKLLKRLEEQLAKMN 599
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
KE+ K +ALGTSK+NYLDPRITVAWCK+ +PIE+I+NK+ KF WA+D+ D
Sbjct: 600 IQATDKEENKQIALGTSKLNYLDPRITVAWCKKFGIPIERIYNKTQREKFAWAIDMAGED 659
Query: 217 FRF 209
F F
Sbjct: 660 FEF 662
[89][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 92.4 bits (228), Expect = 2e-17
Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 5/127 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARK----GKPPSKSPDGKKKKNLSSEALEKKISQTNAKI 407
L EK+D + +K+ + A K G K+ KKKK L +++ + K+
Sbjct: 819 LKEKIDAKKEAIKDAERQVKDAAKDAKHGSVKEKTVYDKKKKML------QRLKEQLTKL 872
Query: 406 EKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
E + D +++ KT+ALGTSK+NYLDPRI+VAWCK++ VPIEKI+NK+ KF WA+D+
Sbjct: 873 EIQETD---RDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKFRWAIDM 929
Query: 226 -DPDFRF 209
PD+ F
Sbjct: 930 AGPDYVF 936
[90][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 92.4 bits (228), Expect = 2e-17
Identities = 46/121 (38%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E + E + ++K+ + D + G K+ + E +K++ + ++ K++
Sbjct: 911 EAIAEAEQIVKDAKRD------------AKHGSVKEKVLYEKKKKQLDRLKEQLMKLEVQ 958
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFR 212
+E+ K +ALGTSK+NYLDPRI+VAWCK+H+VPIEKI+NK+ KF WA+D+ PD+
Sbjct: 959 ATDREENKEIALGTSKLNYLDPRISVAWCKKHDVPIEKIYNKTQRDKFRWAIDMAGPDYV 1018
Query: 211 F 209
F
Sbjct: 1019 F 1019
[91][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 92.4 bits (228), Expect = 2e-17
Identities = 55/130 (42%), Positives = 79/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL---DELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTN 416
NEKL E + KEL L+ A++ + K + KK K ++ E LE +++ +
Sbjct: 760 NEKLRAEGEKEMKAKELEQRLEAAKELEAKFKKENKTKKVEVEGKGMTIEKLENNLAKLD 819
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M + KE+ K VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L KF WA
Sbjct: 820 QRIETMSLQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLREKFDWA 879
Query: 235 M-DVDPDFRF 209
+ VD D+ F
Sbjct: 880 IKSVDEDWEF 889
[92][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 92.0 bits (227), Expect = 3e-17
Identities = 50/123 (40%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L R DL A+ + D K KK + E +K + + ++ K++
Sbjct: 663 LQTKIDAKKDQLANARRDLKSAKADAKVQR--DAKSKKVV--ETKKKAVQRLEEQLMKLE 718
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ D D
Sbjct: 719 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMADED 778
Query: 217 FRF 209
+ F
Sbjct: 779 YEF 781
[93][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 92.0 bits (227), Expect = 3e-17
Identities = 55/126 (43%), Positives = 73/126 (57%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE--- 404
L K+ + + +KE + +L R SKS K A+EKK +Q E
Sbjct: 384 LQLKISDKKKTVKEAKKELKALRVKAKESKSESNNK-------AVEKKKAQVQRLEEQLF 436
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
K++ KE+ K +ALGTSK+NYLDPRITVAWCK+ EVPIEK +NK+ KF WA+D+
Sbjct: 437 KLEVTATDKEENKEIALGTSKLNYLDPRITVAWCKKFEVPIEKAYNKTQREKFAWAIDMA 496
Query: 226 DPDFRF 209
DF F
Sbjct: 497 GEDFVF 502
[94][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 92.0 bits (227), Expect = 3e-17
Identities = 50/123 (40%), Positives = 80/123 (65%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L+E+L E++A KEL+ + +A+K P K+ + E L +I++ + +I +
Sbjct: 732 LDERLSEIKAEFKELKKER-KAKKIDP---------KRGATEEKLLAQIARIDERIATAK 781
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA-MDVDPD 218
++ ++ LK VALGTSKINY+DPR+TVAW K+ +VP+EK+F+K+L KF WA + PD
Sbjct: 782 VQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKLFSKTLREKFPWAEAEAGPD 841
Query: 217 FRF 209
+ F
Sbjct: 842 WVF 844
[95][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 91.7 bits (226), Expect = 4e-17
Identities = 51/123 (41%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R DL A+ K D K KK + E +K + + ++ K++
Sbjct: 798 LQTKIDAKKDQLADARRDLKSAKAEAKVRK--DVKTKKVV--ETKKKAVQRLEEQLMKLE 853
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ D D
Sbjct: 854 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMADKD 913
Query: 217 FRF 209
+ F
Sbjct: 914 YEF 916
[96][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 91.7 bits (226), Expect = 4e-17
Identities = 43/114 (37%), Positives = 73/114 (64%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
+ ++ L+A +K +T+L A++ + S K++ K++ + ++ K++
Sbjct: 638 KSMENLKAKIKAKKTELKEAKEELEKAHSDTAKQRAT-------KRVDRVKEQLRKLKIQ 690
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
K++ K +AL TSK+NYLDPRI+VAWCK+++VPIEKIFNK+ KF WA+D+
Sbjct: 691 RTDKDENKQIALSTSKLNYLDPRISVAWCKKYQVPIEKIFNKTQREKFRWAIDM 744
[97][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 91.3 bits (225), Expect = 5e-17
Identities = 48/123 (39%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R +L A+ + D K KK + S+ +K + + ++ K++
Sbjct: 657 LQSKIDAKKEQLADARRELKSAKADAKVRR--DEKSKKTVESK--KKAVQRIEEQLMKLE 712
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 713 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEED 772
Query: 217 FRF 209
+ F
Sbjct: 773 YEF 775
[98][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 90.5 bits (223), Expect = 8e-17
Identities = 49/126 (38%), Positives = 77/126 (61%), Gaps = 6/126 (4%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSP-----DGKKKKNLSSEALEKKISQTNAKIE 404
+ + LQ + E + L A+K +K+ D K KK + E +K + + + ++
Sbjct: 625 KSMQNLQTKIDEKKKQLSAAKKEHKAAKADAKALHDEKSKKAV--ETKKKAVQRISEQLM 682
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
K++ +E+ K +ALGTSK+NYLDPRI+V+WCK+ VPIEKI++K+ KF WA+D+
Sbjct: 683 KLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKIYSKTQRDKFAWAIDMA 742
Query: 226 DPDFRF 209
D DF F
Sbjct: 743 DEDFEF 748
[99][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 90.5 bits (223), Expect = 8e-17
Identities = 42/81 (51%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = -2
Query: 448 EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 269
E +K + + ++ K++ KE+ K +ALGTSK+NYLDPRITVAWCK+H VPIEKI+
Sbjct: 893 EKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIY 952
Query: 268 NKSLLAKFTWAMDV-DPDFRF 209
NK+ KF WA+D+ PD+ F
Sbjct: 953 NKTQRDKFRWAIDMAGPDYVF 973
[100][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/123 (37%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D +A L + +L A+ + KK + EA +K + + + ++ K++
Sbjct: 637 LQTKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKK----AVEAKKKAVQRIDDQLMKLE 692
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +P+EKI+NK+ KF WA+D+ + D
Sbjct: 693 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKIYNKTQREKFAWAIDMAEDD 752
Query: 217 FRF 209
+ F
Sbjct: 753 YEF 755
[101][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 90.5 bits (223), Expect = 8e-17
Identities = 46/123 (37%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D +A L + +L A+ + KK + EA +K + + + ++ K++
Sbjct: 635 LQTKIDAKKAQLSAAKRELKSAKADAKVRRDEKSKK----AVEAKKKAVQRIDDQLMKLE 690
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +P+EKI+NK+ KF WA+D+ + D
Sbjct: 691 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPVEKIYNKTQREKFAWAIDMAEDD 750
Query: 217 FRF 209
+ F
Sbjct: 751 YEF 753
[102][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 90.5 bits (223), Expect = 8e-17
Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L E + +L A+ K KK + EA +K + + ++ K++
Sbjct: 640 LQTKIDAKKEQLVEAKRELKGAKADAKVRKDEKFKK----AVEAKKKALQRVEEQLMKLE 695
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 696 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKD 755
Query: 217 FRF 209
+ F
Sbjct: 756 YEF 758
[103][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 90.5 bits (223), Expect = 8e-17
Identities = 49/123 (39%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L+E+L E++A KEL+ + RK K K+ + E L ++++ + +I +
Sbjct: 769 LDERLSEIKAEFKELKKE----RKAKKIDA------KRGATEEKLLAQVARIDERIATAK 818
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA-MDVDPD 218
++ ++ LK VALGTSKINY+DPR+TVAW K+ +VP+EK+F+K+L KF WA + PD
Sbjct: 819 VQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDVPLEKLFSKTLREKFPWAEAEAGPD 878
Query: 217 FRF 209
+ F
Sbjct: 879 WVF 881
[104][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 90.1 bits (222), Expect = 1e-16
Identities = 51/116 (43%), Positives = 72/116 (62%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+ Q ++ +L +K K KK+K L E L ++++ K+E +
Sbjct: 853 LKEKIRAKQEAVETCERELKDLKKSNVRDKVAKDKKQKQL--ERLREQLN----KLELQE 906
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
D K++ KT+ALGTSK+NYLDPRI+VAWCK+ VPIEKIFNK+ KF WA+D+
Sbjct: 907 TD---KDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDM 959
[105][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 90.1 bits (222), Expect = 1e-16
Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 17/139 (12%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD-------------GKKKKNLSSEALEK 434
L+E + E + L+ L+ KPPSK + +K N+ E
Sbjct: 824 LDEDIRECEEYLEFLK---------KPPSKRKERFTFVSDVKDFQGNPRKTNVRDGMKED 874
Query: 433 KISQTNAKIEKMQRD----MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 266
++ + K + D +K K+D KTVALGTSKINY+DPRITVA+CK++EVPIEK+FN
Sbjct: 875 VCARRLQALLKRRADHLLKIKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFN 934
Query: 265 KSLLAKFTWAMDVDPDFRF 209
KSL KF WAM F F
Sbjct: 935 KSLRLKFPWAMFAKSTFEF 953
[106][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 90.1 bits (222), Expect = 1e-16
Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 17/139 (12%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD-------------GKKKKNLSSEALEK 434
L+E + E + L+ L+ KPPSK + +K N+ E
Sbjct: 824 LDEDIRECEEYLEFLK---------KPPSKRKERFTFVSDVKDFQGNPRKTNVRDGMKED 874
Query: 433 KISQTNAKIEKMQRD----MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 266
++ + K + D +K K+D KTVALGTSKINY+DPRITVA+CK++EVPIEK+FN
Sbjct: 875 VCARRLQALLKRRADHLLKIKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFN 934
Query: 265 KSLLAKFTWAMDVDPDFRF 209
KSL KF WAM F F
Sbjct: 935 KSLRLKFPWAMFAKSTFEF 953
[107][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 90.1 bits (222), Expect = 1e-16
Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 17/139 (12%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD-------------GKKKKNLSSEALEK 434
L+E + E + L+ L+ KPPSK + +K N+ E
Sbjct: 824 LDEDIRECEEYLEFLK---------KPPSKRKERFTFVSDVKDFQGNPRKTNVRDGMKED 874
Query: 433 KISQTNAKIEKMQRD----MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 266
++ + K + D +K K+D KTVALGTSKINY+DPRITVA+CK++EVPIEK+FN
Sbjct: 875 VCARRLQALLKRRADHLLKIKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFN 934
Query: 265 KSLLAKFTWAMDVDPDFRF 209
KSL KF WAM F F
Sbjct: 935 KSLRLKFPWAMFAKSTFEF 953
[108][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 90.1 bits (222), Expect = 1e-16
Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 2/122 (1%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARK-GKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
++LDE AVLK++ + K GK ++ K + E LE +++ +IE M
Sbjct: 749 KELDERLAVLKDMEKKFQKENKTGKVEAEG------KGQTIEKLENNVAKLEQRIETMSL 802
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ VD D+
Sbjct: 803 QAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIKSVDEDW 862
Query: 214 RF 209
F
Sbjct: 863 EF 864
[109][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 89.7 bits (221), Expect = 1e-16
Identities = 49/125 (39%), Positives = 74/125 (59%), Gaps = 4/125 (3%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEK 401
++ + LQA + + LD A+K +K N +EKK + + ++ K
Sbjct: 407 DQSMANLQAKIDSRKEQLDLAKKELKQAKKEAKGSSDNKLLVVVEKKKKAVQRCEEQLLK 466
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-D 224
M+ +E+ K +AL TSK+NYLDPRI+VAWCK EVP++KI+NK+L KF WA+D+ +
Sbjct: 467 MEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMTE 526
Query: 223 PDFRF 209
DF F
Sbjct: 527 LDFVF 531
[110][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 89.7 bits (221), Expect = 1e-16
Identities = 49/125 (39%), Positives = 74/125 (59%), Gaps = 4/125 (3%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEK 401
++ + LQA + + LD A+K +K N +EKK + + ++ K
Sbjct: 485 DQSMANLQAKIDSRKEQLDLAKKELKQAKKEAKGSSDNKLLVVVEKKKKAVQRCEEQLLK 544
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-D 224
M+ +E+ K +AL TSK+NYLDPRI+VAWCK EVP++KI+NK+L KF WA+D+ +
Sbjct: 545 MEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMTE 604
Query: 223 PDFRF 209
DF F
Sbjct: 605 LDFVF 609
[111][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 89.7 bits (221), Expect = 1e-16
Identities = 39/77 (50%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 505 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 564
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 565 RTKFLWAVHMADENYRF 581
[112][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 89.7 bits (221), Expect = 1e-16
Identities = 39/77 (50%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 898 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 957
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 958 RTKFLWAVHMADENYRF 974
[113][TOP]
>UniRef100_C7E3P0 Topoisomerase family protein (Fragment) n=1 Tax=Caenorhabditis
brenneri RepID=C7E3P0_CAEBE
Length = 159
Score = 89.7 bits (221), Expect = 1e-16
Identities = 41/115 (35%), Positives = 73/115 (63%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
++ +++L+ +K+ + ++ A + ++ D +K +KK + +++K++
Sbjct: 43 DQAMEKLEQKIKDKKKEVKEAEEALKHARGADKEKA--------QKKYDRLKEQLKKLKI 94
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
K++ K +ALGTSK+NYLDPRITVAWCK H+VP+EK+F K+ KF WA+D+
Sbjct: 95 ARTDKDENKQIALGTSKLNYLDPRITVAWCKEHDVPLEKVFTKTHREKFRWAIDM 149
[114][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 89.7 bits (221), Expect = 1e-16
Identities = 39/77 (50%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 505 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 564
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 565 RTKFLWAVHMADENYRF 581
[115][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 89.7 bits (221), Expect = 1e-16
Identities = 39/77 (50%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 893 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 952
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 953 RTKFLWAVHMADENYRF 969
[116][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 89.7 bits (221), Expect = 1e-16
Identities = 45/116 (38%), Positives = 73/116 (62%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+ + ++ + +L ++G S D KK +K++ + +++K++
Sbjct: 848 LKEKIRLKKEAVETCQRELKDMKRGGSVKGSVDRDKK--------QKQLERLKDQLKKLE 899
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
+++ KT+ALGTSK+NYLDPRI+VAWCK+ +VPIEKIFNK+ KF WA+D+
Sbjct: 900 LQETDRDENKTIALGTSKLNYLDPRISVAWCKKFDVPIEKIFNKTQRDKFRWAIDM 955
[117][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 89.7 bits (221), Expect = 1e-16
Identities = 57/130 (43%), Positives = 78/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL---DELQAVLKELRTDLDRARK--GKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E + KEL L++ + K ++ GK + K + E LE I + N
Sbjct: 758 NEKLAAEGEKEMKPKELTDRLEKVEELASKYKKENKTGKVEAEGKGPTVEKLEANIDKIN 817
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ M+ KE K VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L KF WA
Sbjct: 818 QRIENMRIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLREKFDWA 877
Query: 235 M-DVDPDFRF 209
+ VD D+ F
Sbjct: 878 IKSVDEDWEF 887
[118][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 89.7 bits (221), Expect = 1e-16
Identities = 54/125 (43%), Positives = 79/125 (63%), Gaps = 5/125 (4%)
Frame = -2
Query: 568 EKLDEL-QAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEK---KISQTNAKIEK 401
EK +EL ++ LKE +D K + + GK + +SE+ EK +I + + +IE
Sbjct: 633 EKQEELPESQLKEWMARVDELEK-QYNEELESGKVQLKTNSESAEKLKMQIEKLDQRIET 691
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VD 224
+K KED VALGTSKINY+DPR++V +CK++ VPIEK+F KSL KF WA++ D
Sbjct: 692 ATIQLKDKEDNSQVALGTSKINYIDPRLSVVFCKKYGVPIEKVFTKSLRDKFKWAIESAD 751
Query: 223 PDFRF 209
++RF
Sbjct: 752 ENWRF 756
[119][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 89.7 bits (221), Expect = 1e-16
Identities = 39/77 (50%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 896 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 955
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 956 RTKFLWAVHMADENYRF 972
[120][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 89.4 bits (220), Expect = 2e-16
Identities = 40/90 (44%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = -2
Query: 475 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKR 296
G K+ ++++ K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 965 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1024
Query: 295 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1025 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1054
[121][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 89.4 bits (220), Expect = 2e-16
Identities = 40/90 (44%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = -2
Query: 475 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKR 296
G K+ ++++ K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 953 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1012
Query: 295 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1013 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1042
[122][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 89.4 bits (220), Expect = 2e-16
Identities = 50/136 (36%), Positives = 83/136 (61%), Gaps = 14/136 (10%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPD------GKKKKNL--------SSEALE 437
+N KL+ ++ ++EL ++ K K P++ + G +KKN + ++
Sbjct: 465 INTKLECMKTYIQEL----EQHYKKKNPNEYEEEVQLEEGSQKKNSIFIKKFPGQHDKIK 520
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
+ I +T K +K + ++ KE+ K +ALGTSK NY DPRI+VA+CK H+VPIE++F+K+L
Sbjct: 521 QTIQKTQEKYQKELKGLEKKEENKEIALGTSKTNYNDPRISVAFCKVHDVPIERVFSKTL 580
Query: 256 LAKFTWAMDVDPDFRF 209
KF WAM D +++F
Sbjct: 581 RNKFIWAMATDSNWKF 596
[123][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/123 (35%), Positives = 78/123 (63%), Gaps = 3/123 (2%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLD--RARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +D L+ ++ R ++D A + G K+ ++++ K++ + +++K++
Sbjct: 941 KSMDNLKEKIRAKRDNIDDCEAEYHDLKKAAKRGSVKEKVNADKKAKQLERLKDQLKKLE 1000
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+++ KT+AL TSK+NYLDPRI+VAWCK++ VPIEKIFNK+ KF WA+ + D +
Sbjct: 1001 LQETDRDENKTIALSTSKLNYLDPRISVAWCKKNGVPIEKIFNKTQRTKFLWAIHMADEN 1060
Query: 217 FRF 209
+RF
Sbjct: 1061 YRF 1063
[124][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 89.0 bits (219), Expect = 2e-16
Identities = 53/124 (42%), Positives = 78/124 (62%), Gaps = 2/124 (1%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARK-GKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKM 398
++E + LQAV KEL + K GK +++ + + E LE I++ + ++E M
Sbjct: 748 VSELEERLQAV-KELEKKFKKENKTGKVEAEA------RGATVEKLENSINKIDQRVETM 800
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDP 221
+ KED K VALGTSKINY+DPR+TV + K+++VPIEK F+K+L KF WA+ VD
Sbjct: 801 SVQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKYDVPIEKFFSKALREKFEWAIKSVDE 860
Query: 220 DFRF 209
D+ F
Sbjct: 861 DWEF 864
[125][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 89.0 bits (219), Expect = 2e-16
Identities = 49/123 (39%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK DE++ + ++ DL++ K + P+ KKNL+ E L++++ +I
Sbjct: 661 LTEKSDEIKEKMAKI-DDLEKEYKAELNGAKPE--VKKNLTVEKLQQQVEVIENRIVTTT 717
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 718 LQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIESADEN 777
Query: 217 FRF 209
+RF
Sbjct: 778 WRF 780
[126][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/124 (36%), Positives = 75/124 (60%), Gaps = 4/124 (3%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEKM 398
+ + LQ + + L A++ +K+ +K S +A+E K + + ++ K+
Sbjct: 628 KSMQNLQTKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKKAVESKKKAVQRIEDQLMKL 687
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DP 221
+ +E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ +
Sbjct: 688 EVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEK 747
Query: 220 DFRF 209
D+ F
Sbjct: 748 DYEF 751
[127][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 88.6 bits (218), Expect = 3e-16
Identities = 45/124 (36%), Positives = 75/124 (60%), Gaps = 4/124 (3%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK---ISQTNAKIEKM 398
+ + LQ + + L A++ +K+ +K S +A+E K + + ++ K+
Sbjct: 628 KSMQNLQTKIDAKKEQLSAAKRELKGAKADAKVRKDEKSKKAVESKKKAVQRIEDQLMKL 687
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DP 221
+ +E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ +
Sbjct: 688 EVQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEK 747
Query: 220 DFRF 209
D+ F
Sbjct: 748 DYEF 751
[128][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 88.6 bits (218), Expect = 3e-16
Identities = 48/123 (39%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
++ K ++L A +EL+ A+ K D K KK + S+ +K + + ++ K++
Sbjct: 692 IDAKKEQLSAAKRELKGAKADAKVRK------DEKSKKAVESK--KKAVQRIEDQLMKLE 743
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 744 VQATDREENKQIALGTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEKD 803
Query: 217 FRF 209
+ F
Sbjct: 804 YEF 806
[129][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 88.6 bits (218), Expect = 3e-16
Identities = 53/127 (41%), Positives = 75/127 (59%), Gaps = 5/127 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSP-----DGKKKKNLSSEALEKKISQTNAK 410
L +KL + +A L+ L D GK SK + K +K+ + ++L +KI
Sbjct: 522 LKKKLADQEATLRGLEGRRDELL-GKTVSKDVKEIIVEKKLEKSNNMDSLVRKIKSQKLA 580
Query: 409 IEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
E+ + + KED KTV+L TSKINY+DPRI+VA+CK H+ PIEKIF K++ KF WAM
Sbjct: 581 AERTKIQIADKEDNKTVSLTTSKINYMDPRISVAFCKSHDCPIEKIFAKTIRNKFPWAMH 640
Query: 229 VDPDFRF 209
+RF
Sbjct: 641 SKSTWRF 647
[130][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 88.6 bits (218), Expect = 3e-16
Identities = 39/77 (50%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+H VPIEKIFNK+
Sbjct: 914 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIFNKTQ 973
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 974 RTKFLWAVHMADENYRF 990
[131][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 88.6 bits (218), Expect = 3e-16
Identities = 51/122 (41%), Positives = 74/122 (60%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L+ A++ + K + KK K ++ E LE ++ + + +IE M
Sbjct: 788 EREMKAKELEERLEAAKELEAKFKRENKTKKVEAEGKGITIEKLENQLLKLSQRIENMSL 847
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ VD D+
Sbjct: 848 QAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIKSVDEDW 907
Query: 214 RF 209
F
Sbjct: 908 EF 909
[132][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 88.6 bits (218), Expect = 3e-16
Identities = 52/123 (42%), Positives = 77/123 (62%), Gaps = 3/123 (2%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARK--GKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
E LDE +VLKE ++ R+ + S K + S E LEK+I + + +IE
Sbjct: 723 ELLDE--SVLKEWLEKVEELRQQYARELKTSVTEVKSSSNSIEKLEKQIEKLDQRIETSS 780
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
++ KE+ V+LGTSKINY+DPR++V +CK++ VPIE+IF KSL KF WA++ D +
Sbjct: 781 IQLRDKEENSQVSLGTSKINYIDPRLSVVFCKKYGVPIERIFTKSLREKFKWAIESADEN 840
Query: 217 FRF 209
+RF
Sbjct: 841 WRF 843
[133][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 88.6 bits (218), Expect = 3e-16
Identities = 51/122 (41%), Positives = 74/122 (60%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L+ A++ + K + KK K ++ E LE ++ + + +IE M
Sbjct: 788 EREMKAKELEERLEAAKELEAKFKRENKTKKVEAEGKGITIEKLENQLLKLSQRIENMSL 847
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ VD D+
Sbjct: 848 QAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIKSVDEDW 907
Query: 214 RF 209
F
Sbjct: 908 EF 909
[134][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 88.6 bits (218), Expect = 3e-16
Identities = 44/115 (38%), Positives = 72/115 (62%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
+E + +L+ +K+ + ++ A KS G +K E +KK + +++K++
Sbjct: 618 DESMQKLEQKIKDKKKEVKEAEAAL---KSARGAEK-----EKAQKKYDRLKEQLKKLKI 669
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
K++ K +ALGTSK+NY+DPRITVAWCK+ EVP+EK+F K+ KF WA+D+
Sbjct: 670 SRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDM 724
[135][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 88.6 bits (218), Expect = 3e-16
Identities = 44/115 (38%), Positives = 72/115 (62%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
+E + +L+ +K+ + ++ A KS G +K E +KK + +++K++
Sbjct: 690 DESMQKLEQKIKDKKKEVKEAEAAL---KSARGAEK-----EKAQKKYDRLKEQLKKLKI 741
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
K++ K +ALGTSK+NY+DPRITVAWCK+ EVP+EK+F K+ KF WA+D+
Sbjct: 742 SRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDM 796
[136][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 88.2 bits (217), Expect = 4e-16
Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R +L A+ + D K KK + S+ +K + + ++ K++
Sbjct: 648 LQSKIDAKKEQLADARRELKSAKADAKVRR--DEKSKKAVESK--KKAVQRIEEQLMKLE 703
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +AL TSK+NYLDPRI+VAWCK+ +PIEKI+NK+ KF WA+D+ + D
Sbjct: 704 VQATDREENKQIALSTSKLNYLDPRISVAWCKKWGIPIEKIYNKTQREKFAWAIDMAEED 763
Query: 217 FRF 209
+ F
Sbjct: 764 YEF 766
[137][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 88.2 bits (217), Expect = 4e-16
Identities = 41/90 (45%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
Frame = -2
Query: 475 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKR 296
G K+ + ++ K + + +++K++ +++ KT+ALGTSK+NYLDPRITVAWCK+
Sbjct: 956 GSVKERVIADKKGKILERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKK 1015
Query: 295 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1016 YGVPIEKIFNKTHRTKFLWAIHMADENYRF 1045
[138][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 88.2 bits (217), Expect = 4e-16
Identities = 40/85 (47%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
Frame = -2
Query: 460 NLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 281
N E K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+++VPI
Sbjct: 886 NSRDEKKGKQLDRLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPI 945
Query: 280 EKIFNKSLLAKFTWAMDV-DPDFRF 209
EKIFNK+ KF WA+ + D ++RF
Sbjct: 946 EKIFNKTQRTKFLWAVHMADENYRF 970
[139][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 88.2 bits (217), Expect = 4e-16
Identities = 56/130 (43%), Positives = 78/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + K+ S E LE I++
Sbjct: 869 NEKLAAEGEKEMKASELEHRLEAVKEMENKFMRENKTGKVEVEGKSPSVEKLEAAITKLE 928
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ VPIEK F+KSL KF WA
Sbjct: 929 QRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWA 988
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 989 IKSVDENWEF 998
[140][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 88.2 bits (217), Expect = 4e-16
Identities = 55/130 (42%), Positives = 78/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGK---KKKNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + K+ S E LE I++
Sbjct: 757 NEKLAAEGEKEMKASELESRLEAVKEMENKFKKENKTGKVDVEGKSSSVEKLEAAITKLE 816
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KE+ K VALGTSKINY+DPR+TV + K+ VPIEK F+KSL KF WA
Sbjct: 817 QRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWA 876
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 877 IKSVDENWEF 886
[141][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 87.4 bits (215), Expect = 7e-16
Identities = 46/118 (38%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK--ISQTNAKIEK 401
L K++ + L +++L +A+K S D K L + + KK + + ++ K
Sbjct: 502 LQSKIEARKEQLVLAKSELKQAKKEAKAKGSADAK----LQALVVRKKMAVKRCEEQLLK 557
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
++ +E+ K +ALGTSK+NYLDPRI+VAWCK+ EVP++KI+NKS KF WA+D+
Sbjct: 558 LEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKIYNKSQRDKFAWAIDM 615
[142][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 87.4 bits (215), Expect = 7e-16
Identities = 46/118 (38%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKK--ISQTNAKIEK 401
L K++ + L +++L +A+K S D K L + + KK + + ++ K
Sbjct: 502 LQSKIEARKEQLVLAKSELKQAKKEAKAKGSADAK----LQALVVRKKMAVKRCEEQLLK 557
Query: 400 MQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
++ +E+ K +ALGTSK+NYLDPRI+VAWCK+ EVP++KI+NKS KF WA+D+
Sbjct: 558 LEVQATDREENKQIALGTSKLNYLDPRISVAWCKKMEVPVDKIYNKSQRDKFAWAIDM 615
[143][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 87.4 bits (215), Expect = 7e-16
Identities = 39/90 (43%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -2
Query: 475 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKR 296
G K+ ++++ K++ + +++K++ +++ KT+AL TSK+NYLDPRI+VAWCK+
Sbjct: 908 GSVKEKVNADKKGKQLERLKEQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKK 967
Query: 295 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 968 NGVPIEKIFNKTQRTKFLWAIHMADENYRF 997
[144][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 87.4 bits (215), Expect = 7e-16
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 4/92 (4%)
Frame = -2
Query: 472 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRH 293
K + E +KK Q +++K++ K++ K +ALGTSK+NY+DPRITVAWCK+
Sbjct: 749 KSARGAEKEKAQKKYDQKKEQLKKLKIQRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 808
Query: 292 EVPIEKIFNKSLLAKFTWAMDV----DPDFRF 209
EVP+E++F K+ KF WA+D+ D +F F
Sbjct: 809 EVPLERVFTKTHREKFRWAIDMTMTTDEEFVF 840
[145][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6JVY3_SCHJY
Length = 654
Score = 87.4 bits (215), Expect = 7e-16
Identities = 51/126 (40%), Positives = 75/126 (59%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKL---DELQAVL-KELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKI 407
L E+L DEL+A L +ELRT A + S+E LEK++ + + +I
Sbjct: 544 LEERLKAADELKAKLDEELRTGAVEAGRS---------------SNEQLEKRLIKMDERI 588
Query: 406 EKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV 227
+ M + K++ KT ALGTSKINY+DPR+T + CKR +PIEK+F+K++ KF WA D
Sbjct: 589 KVMSNSIIDKDENKTTALGTSKINYIDPRLTFSLCKRENIPIEKLFSKTIRDKFNWAADT 648
Query: 226 DPDFRF 209
D+ +
Sbjct: 649 PADWNW 654
[146][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 87.0 bits (214), Expect = 9e-16
Identities = 38/77 (49%), Positives = 60/77 (77%), Gaps = 1/77 (1%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+++VPIEKIFNK+
Sbjct: 504 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIFNKTQ 563
Query: 256 LAKFTWAMDV-DPDFRF 209
KF WA+ + D ++RF
Sbjct: 564 RTKFLWAVHMADENYRF 580
[147][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 87.0 bits (214), Expect = 9e-16
Identities = 54/130 (41%), Positives = 79/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + ++ + E LE I++
Sbjct: 742 NEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQ 801
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ +VPIEK F+KSL KF WA
Sbjct: 802 QRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWA 861
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 862 IKSVDENWEF 871
[148][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 87.0 bits (214), Expect = 9e-16
Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R ++ + + K ++ GK + K + E LE I +
Sbjct: 752 NEKLAAEGEKEMKAKELENRLEVVKDMEKKFNKENKTGKVEAEGKGPTVEKLENAIQKLE 811
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ VPIEK F+KSL KF WA
Sbjct: 812 QRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWA 871
Query: 235 M-DVDPDFRF 209
+ V+ D+ F
Sbjct: 872 IKSVEQDWEF 881
[149][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 87.0 bits (214), Expect = 9e-16
Identities = 54/130 (41%), Positives = 79/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + ++ + E LE I++
Sbjct: 742 NEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQ 801
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ +VPIEK F+KSL KF WA
Sbjct: 802 QRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWA 861
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 862 IKSVDENWEF 871
[150][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 87.0 bits (214), Expect = 9e-16
Identities = 54/130 (41%), Positives = 79/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + ++ + E LE I++
Sbjct: 742 NEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQ 801
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ +VPIEK F+KSL KF WA
Sbjct: 802 QRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWA 861
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 862 IKSVDENWEF 871
[151][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 87.0 bits (214), Expect = 9e-16
Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R ++ + + K ++ GK + K + E LE I +
Sbjct: 752 NEKLAAEGEKEMKAKELENRLEVVKDMEKKFNKENKTGKVEAEGKGPTVEKLENAIQKLE 811
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KED K VALGTSKINY+DPR+TV + K+ VPIEK F+KSL KF WA
Sbjct: 812 QRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWA 871
Query: 235 M-DVDPDFRF 209
+ V+ D+ F
Sbjct: 872 IKSVEQDWEF 881
[152][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 86.7 bits (213), Expect = 1e-15
Identities = 46/123 (37%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K++ + + E + +L +AR G G + E E+ + + ++ ++
Sbjct: 537 LQLKIEAKKKQVAEAKAELKQARAGHKCR----GDDRSRSFLEKRERLLEKLEEQLMRLS 592
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
KE+ K VALGTSK+NYLDPRI+VAWCKR VP+E+I+NK+ +F WA+D+ D
Sbjct: 593 TQATDKEESKQVALGTSKLNYLDPRISVAWCKRFGVPVERIYNKTQRERFAWALDMAGED 652
Query: 217 FRF 209
F F
Sbjct: 653 FEF 655
[153][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 86.3 bits (212), Expect = 2e-15
Identities = 43/111 (38%), Positives = 73/111 (65%), Gaps = 1/111 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDL-DRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKM 398
L EK+D+ + ++E++ + D AR K G K+ L + +K + + +++K+
Sbjct: 142 LKEKIDQKREQIEEMQRQVKDAARDAK------HGSVKEKLVHDKKKKSLDRLKEQLKKL 195
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+ +++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 196 EVQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[154][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+ + + E R +L RAR K + KS +KK E L+++++Q + +
Sbjct: 385 LQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRWLLEKLQEQLAQLSVQAT 444
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K VALGTSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ +
Sbjct: 445 D-------KEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMA 497
Query: 226 DPDFRF 209
DF F
Sbjct: 498 GEDFEF 503
[155][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+ + + E R +L RAR K + KS +KK E L+++++Q + +
Sbjct: 385 LQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRWLLEKLQEQLAQLSVQAT 444
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K VALGTSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ +
Sbjct: 445 D-------KEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMA 497
Query: 226 DPDFRF 209
DF F
Sbjct: 498 GEDFEF 503
[156][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+ + + E R +L RAR K + KS +KK E L+++++Q + +
Sbjct: 385 LQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQAT 444
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K VALGTSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ +
Sbjct: 445 D-------KEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMA 497
Query: 226 DPDFRF 209
DF F
Sbjct: 498 GEDFEF 503
[157][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 86.3 bits (212), Expect = 2e-15
Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 3/122 (2%)
Frame = -2
Query: 565 KLDELQAVLKELRTDLDRA--RKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
K EL+ L ++ T+L++ R+ K +GK + E +E I + +IE M+
Sbjct: 755 KASELEERL-QVATELEKKYNRENKTGKVEAEGKAP---TVEKIEANIQKLEQRIETMEL 810
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KED K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ VD D+
Sbjct: 811 QAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKALREKFEWAIKSVDEDW 870
Query: 214 RF 209
F
Sbjct: 871 EF 872
[158][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 2/122 (1%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARK-GKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
++L+E AVLK++ + K GK + K + E LE +++ +IE M
Sbjct: 745 KELEERLAVLKDMEKKFQKENKTGKVEVEG------KGQTVEKLENNVTKLEQRIENMSL 798
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ V+ D+
Sbjct: 799 QAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIKSVEEDW 858
Query: 214 RF 209
F
Sbjct: 859 EF 860
[159][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+ + + E R +L RAR K + KS +KK E L+++++Q + +
Sbjct: 483 LQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQAT 542
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K VALGTSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ +
Sbjct: 543 D-------KEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMA 595
Query: 226 DPDFRF 209
DF F
Sbjct: 596 GEDFEF 601
[160][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 86.3 bits (212), Expect = 2e-15
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIE 404
L K+ + + E R +L RAR K + KS +KK E L+++++Q + +
Sbjct: 483 LQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQAT 542
Query: 403 KMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV- 227
KE+ K VALGTSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ +
Sbjct: 543 D-------KEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMA 595
Query: 226 DPDFRF 209
DF F
Sbjct: 596 GEDFEF 601
[161][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 85.9 bits (211), Expect = 2e-15
Identities = 49/121 (40%), Positives = 77/121 (63%), Gaps = 1/121 (0%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
+K+D+L+ K+ +T+L + GK K+ S E LEK++ + +I+
Sbjct: 636 KKVDDLE---KQYKTEL---KTGKVELKAT------MQSVEKLEKQVEKLEERIKTSSIQ 683
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPDFR 212
+K KE+ V+LGTSKINY+DPR++V +CK++ VPIEKIF K+L KF WA++ D ++R
Sbjct: 684 LKDKEENSQVSLGTSKINYIDPRLSVVFCKKYNVPIEKIFTKTLREKFAWAIESADENWR 743
Query: 211 F 209
F
Sbjct: 744 F 744
[162][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 85.9 bits (211), Expect = 2e-15
Identities = 48/123 (39%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +KLD++ + KE + +L + GKP KN + E L+++I +I +
Sbjct: 665 IKDKLDKIDELEKEYKKEL---KTGKPIIT-------KNATVEKLKQQIETLENRILNVS 714
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 715 FQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLREKFNWAIESTDEN 774
Query: 217 FRF 209
+RF
Sbjct: 775 WRF 777
[163][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 85.9 bits (211), Expect = 2e-15
Identities = 41/81 (50%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = -2
Query: 448 EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 269
E LEK I + +I+ +K KE+ V+LGTSKINY+DPR++V +CK+ ++PIEKIF
Sbjct: 719 EKLEKNIEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKFDIPIEKIF 778
Query: 268 NKSLLAKFTWAMD-VDPDFRF 209
KSL KF WA++ VD ++RF
Sbjct: 779 TKSLREKFRWAIESVDENWRF 799
[164][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 85.9 bits (211), Expect = 2e-15
Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ EKLD++ + KE + +L + GKP + K + E L+ ++ +I
Sbjct: 737 IKEKLDKITELEKEYKKEL---KTGKP-------EIPKGATVEKLKTQVENMENRIVSTT 786
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D D
Sbjct: 787 LQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLREKFKWAIESTDKD 846
Query: 217 FRF 209
+RF
Sbjct: 847 WRF 849
[165][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 85.5 bits (210), Expect = 3e-15
Identities = 43/123 (34%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K+ + +L + + ++ S + G K +E K++ + +++K++
Sbjct: 509 LRKKIHNKSNAINDLEAEFNELKR----SATLSGTAKDKKIAECKGKQLERLKDQLKKLK 564
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+ +E+ K VAL TSK+NY+DPRI+VAWCK++ VPIEKIFNK+ KF WA+ + D +
Sbjct: 565 LEETNREENKCVALTTSKLNYIDPRISVAWCKKNNVPIEKIFNKTQRTKFLWAIHMADEN 624
Query: 217 FRF 209
+ F
Sbjct: 625 YHF 627
[166][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 85.5 bits (210), Expect = 3e-15
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL---DELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTN 416
NEKL E + +KEL L+ A + K + KK K + E E +++ +
Sbjct: 776 NEKLRAEGEKEMKVKELEKRLEVAEELAAKFKKENKTKKVEAEGKGATIEKYENNLAKLD 835
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+I+ M + KED K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA
Sbjct: 836 QRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVPIEKFFSKTLREKFDWA 895
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 896 IKSVDENWEF 905
[167][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 85.5 bits (210), Expect = 3e-15
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL---DELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTN 416
NEKL E + +KEL L+ A + K + KK K + E E +++ +
Sbjct: 776 NEKLRAEGEKEMKVKELEKRLEVAEELAAKFKKENKTKKVEAEGKGATIEKYENNLAKLD 835
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+I+ M + KED K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA
Sbjct: 836 QRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVPIEKFFSKTLREKFDWA 895
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 896 IKSVDENWEF 905
[168][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 85.5 bits (210), Expect = 3e-15
Identities = 53/130 (40%), Positives = 78/130 (60%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKL-----DELQAVLKELRTDLDRARKGKPPSKSPDGKKK---KNLSSEALEKKISQTN 416
NEKL E++A E R + + + K ++ GK + K + + +E I++
Sbjct: 755 NEKLAAEGEKEMKATELESRLQVAKDLEKKFNKENKTGKVEAEGKAPTVDKIEAAITKLE 814
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ + KE+ K VALGTSKINY+DPR+TV + K+ +VPIEK F+KSL KF WA
Sbjct: 815 QRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKSLREKFEWA 874
Query: 235 M-DVDPDFRF 209
+ VD D+ F
Sbjct: 875 IKSVDEDWEF 884
[169][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 85.1 bits (209), Expect = 3e-15
Identities = 42/110 (38%), Positives = 71/110 (64%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+D+ + + + + + A+K + G K+ L E +K + + +++K++
Sbjct: 142 LKEKIDQKREQIADAQRQVKDAQKD-----AKHGSVKEKLVYEKKKKMLDKLKDQLKKLE 196
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ KT+ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 197 VQETDRDENKTIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[170][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 84.7 bits (208), Expect = 5e-15
Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 9/130 (6%)
Frame = -2
Query: 571 NEKLD---ELQAVLKELRTDLDRARK--GKPPSKSPDGK---KKKNLSSEALEKKISQTN 416
NEKL E + KEL L++A + K ++ GK + K + E LE + +
Sbjct: 776 NEKLKADGEKELKQKELNERLEKAEELAAKYKKENKTGKIEAEGKGPTVEKLEANVEKIV 835
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+IE M+ M+ KE K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA
Sbjct: 836 QRIENMKIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFGVPIEKFFSKTLREKFDWA 895
Query: 235 M-DVDPDFRF 209
+ VD ++ F
Sbjct: 896 IKSVDENWEF 905
[171][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 84.3 bits (207), Expect = 6e-15
Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EKL +++A +E R +++ S + + K S E L+ +I + +I
Sbjct: 652 LQEKLSKIKASEEEYRHEIE----------SGEVEVTKGASVEKLKVQIEKIENRILNTN 701
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ VPIEK+F K+L KFTWA++ D +
Sbjct: 702 FQLKDKEDNSEVSLGTSKLNYIDPRLTVMFAKKFNVPIEKLFTKTLREKFTWAIESADEN 761
Query: 217 FRF 209
+RF
Sbjct: 762 WRF 764
[172][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 84.0 bits (206), Expect = 8e-15
Identities = 49/120 (40%), Positives = 71/120 (59%), Gaps = 2/120 (1%)
Frame = -2
Query: 562 LDELQAVLKELRTDL-DRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
LDE +KE DL + + GKP KS +K E L+ +I T +++
Sbjct: 642 LDEKMEKIKEQEKDLAEELKTGKPVMKSTTTVEKLKAQVEKLDGRIVNTTFQLQD----- 696
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 209
KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D ++RF
Sbjct: 697 --KEDNSEVSLGTSKLNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIESADENWRF 754
[173][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 84.0 bits (206), Expect = 8e-15
Identities = 46/123 (37%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + + + +L A+K +K D +K N E+ ++ + +T ++ +M+
Sbjct: 385 LKSKIDAKKEQILLAKKELKEAKK---EAKEKDSEKL-NKVVESKKRAVQRTEEQLMRME 440
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +AL TSK+NYLDPRI+VAWCK+ V +EKI+NK+ KF WA+D+ + D
Sbjct: 441 VQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKIYNKTYRDKFAWAIDMTETD 500
Query: 217 FRF 209
F F
Sbjct: 501 FIF 503
[174][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 84.0 bits (206), Expect = 8e-15
Identities = 36/70 (51%), Positives = 54/70 (77%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K++ + +++K++ +++ KT+ALGTSK+NYLDPRI+VAWCK+ VPIEKIFNK+
Sbjct: 893 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQ 952
Query: 256 LAKFTWAMDV 227
KF WA+D+
Sbjct: 953 RDKFRWAIDM 962
[175][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 84.0 bits (206), Expect = 8e-15
Identities = 47/117 (40%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTK 377
EL A LK+L D ++ + S +GK + E L ++ + ++ M+ +K K
Sbjct: 649 ELNAKLKDL-ADTNKQYLKEIKSNKVEGKG----TVEKLRAQVEKLETRVTTMRMQLKDK 703
Query: 376 EDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDFRF 209
ED +VALGTSK+NY+DPR+TV + K+++VPIEK+F K+L KF WA+ D D+ F
Sbjct: 704 EDNSSVALGTSKMNYIDPRLTVKFSKKYDVPIEKLFTKTLRDKFQWAIQSADEDWEF 760
[176][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 84.0 bits (206), Expect = 8e-15
Identities = 48/123 (39%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +KLD++ + KE + +L + GKP KN + E L+++I KI +
Sbjct: 668 IKDKLDKIDELEKEYQKEL---KTGKPIVT-------KNATVEKLKQQIETLENKILNVS 717
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+ V + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 718 IQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIESADEN 777
Query: 217 FRF 209
+RF
Sbjct: 778 WRF 780
[177][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 84.0 bits (206), Expect = 8e-15
Identities = 48/123 (39%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +KLD++ + KE + +L + GKP KN + E L+++I KI +
Sbjct: 668 IKDKLDKIDELEKEYQKEL---KTGKPIVT-------KNATVEKLKQQIETLENKILNVS 717
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+ V + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 718 IQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIESADEN 777
Query: 217 FRF 209
+RF
Sbjct: 778 WRF 780
[178][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 84.0 bits (206), Expect = 8e-15
Identities = 48/121 (39%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
++L+E V K L R K K + K ++ E LE ++ + + +IE M
Sbjct: 796 KELEERLEVAKALEAKFKRENKTKKVEA-----EGKGVTIEKLENQLLKLSQRIENMSLQ 850
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDFR 212
+ +E+ K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA+ V+ D+
Sbjct: 851 AEDRENNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKTLREKFDWAIKSVEEDWE 910
Query: 211 F 209
F
Sbjct: 911 F 911
[179][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 84.0 bits (206), Expect = 8e-15
Identities = 49/120 (40%), Positives = 71/120 (59%), Gaps = 2/120 (1%)
Frame = -2
Query: 562 LDELQAVLKELRTDL-DRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
LDE +KE DL + + GKP KS +K E L+ +I T +++
Sbjct: 642 LDEKMEKIKEQEKDLAEELKTGKPVMKSTTTVEKLKAQVEKLDGRIVNTTFQLQD----- 696
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 209
KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D ++RF
Sbjct: 697 --KEDNSEVSLGTSKLNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIESADENWRF 754
[180][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 83.6 bits (205), Expect = 1e-14
Identities = 45/95 (47%), Positives = 60/95 (63%), Gaps = 2/95 (2%)
Frame = -2
Query: 487 KSPDGKKKKNL--SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRIT 314
++P K K+ L S E + I + + I K K++LK+VAL TSKINY+DPRIT
Sbjct: 921 ETPKKKVKRALPDSVEKCKAAIERVDTSINKWNIKKTEKDELKSVALTTSKINYIDPRIT 980
Query: 313 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
AW KR + I K+F+KSL KF WAMDV+ D+ F
Sbjct: 981 AAWAKRVGLDIGKLFSKSLREKFPWAMDVEEDWEF 1015
[181][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 83.6 bits (205), Expect = 1e-14
Identities = 40/83 (48%), Positives = 59/83 (71%), Gaps = 1/83 (1%)
Frame = -2
Query: 454 SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
S E L+ +I + +I MK KED TVAL TSKI+Y+DPR++VA+CK+++VP+EK
Sbjct: 650 SVEKLKAQIDKLEQRIRTTSIQMKDKEDNSTVALSTSKISYIDPRLSVAFCKKYDVPLEK 709
Query: 274 IFNKSLLAKFTWAMD-VDPDFRF 209
+F K+L KF WA++ D ++RF
Sbjct: 710 VFTKTLREKFKWAIESADENWRF 732
[182][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 83.6 bits (205), Expect = 1e-14
Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L+ A + + K + KK K ++ E LE ++ + +IE M
Sbjct: 779 EKEMKAKELEERLEAANELEAKFKKENKSKKVVPEGKGVTVEKLENQLLKLGQRIENMSL 838
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + ++ VP+EK F+K+L KF WA+ VD ++
Sbjct: 839 QAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAIKSVDENW 898
Query: 214 RF 209
F
Sbjct: 899 EF 900
[183][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 83.6 bits (205), Expect = 1e-14
Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L+ A + + K + KK K ++ E LE ++ + +IE M
Sbjct: 704 EKEMKAKELEERLEAANELEAKFKKENKSKKVVPEGKGVTVEKLENQLLKLGQRIENMSL 763
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + ++ VP+EK F+K+L KF WA+ VD ++
Sbjct: 764 QAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAIKSVDENW 823
Query: 214 RF 209
F
Sbjct: 824 EF 825
[184][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 83.6 bits (205), Expect = 1e-14
Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L+ A + + K + KK K ++ E LE ++ + +IE M
Sbjct: 784 EKEMKAKELEERLEAANELEAKFKKENKSKKVVPEGKGVTVEKLENQLLKLGQRIENMSL 843
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSKINY+DPR+TV + ++ VP+EK F+K+L KF WA+ VD ++
Sbjct: 844 QAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVPMEKFFSKTLREKFDWAIKSVDENW 903
Query: 214 RF 209
F
Sbjct: 904 EF 905
[185][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 83.6 bits (205), Expect = 1e-14
Identities = 51/120 (42%), Positives = 70/120 (58%), Gaps = 1/120 (0%)
Frame = -2
Query: 565 KLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDM 386
+LD +KE+ +L ++ K +GK EA K+ Q +IE M+
Sbjct: 772 ELDSRLEAVKEM--ELRFKKENKTGKVEAEGKSPSVARIEAAITKLEQ---RIETMELQA 826
Query: 385 KTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDFRF 209
+ KED K VALGTSKINY+DPR+TV + K+ VPIEK F+KSL KF WA+ VD ++ F
Sbjct: 827 QDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF 886
[186][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 83.2 bits (204), Expect = 1e-14
Identities = 37/73 (50%), Positives = 53/73 (72%)
Frame = -2
Query: 448 EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 269
E L++ + + +I +K KED TVALGTSKINY+DPR++VA+CK+ +VPIEK+F
Sbjct: 705 EKLKQNVEKLEKRITNCSLQLKDKEDNSTVALGTSKINYIDPRLSVAFCKKFDVPIEKVF 764
Query: 268 NKSLLAKFTWAMD 230
K+L KF WA++
Sbjct: 765 TKTLRDKFRWAIE 777
[187][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 82.8 bits (203), Expect = 2e-14
Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 7/128 (5%)
Frame = -2
Query: 571 NEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQR 392
++ + LQ+ + + L A+ G +K K K S L+ + + A +++ ++
Sbjct: 507 DQSMATLQSKIDARKEQLALAKSGLKQAKKE--AKAKGSSEFKLQTLVERKKAAVKRCEQ 564
Query: 391 DMKT------KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
+K +E+ K +ALGTSK+NYLDPRI+VAWCK +P++KI+NKS KF WA+D
Sbjct: 565 LLKMEIQATDREENKQIALGTSKLNYLDPRISVAWCKNMGLPVDKIYNKSQRDKFAWAID 624
Query: 229 V-DPDFRF 209
+ + DF F
Sbjct: 625 MTEVDFEF 632
[188][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 82.8 bits (203), Expect = 2e-14
Identities = 46/108 (42%), Positives = 69/108 (63%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++DE Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQIDEAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[189][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 82.8 bits (203), Expect = 2e-14
Identities = 42/83 (50%), Positives = 58/83 (69%), Gaps = 1/83 (1%)
Frame = -2
Query: 454 SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
S E LEK I + + +I Q ++ +E V+LGTSKINY+DPR++V +CK++ VPIEK
Sbjct: 635 SVEKLEKAIERLDQRISTSQVQLQDREANSEVSLGTSKINYIDPRLSVVFCKKYGVPIEK 694
Query: 274 IFNKSLLAKFTWAMD-VDPDFRF 209
IF KSL KF WA++ VD +RF
Sbjct: 695 IFTKSLREKFKWAIESVDETWRF 717
[190][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 82.8 bits (203), Expect = 2e-14
Identities = 44/122 (36%), Positives = 72/122 (59%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L + L+++ + +E + + + KG+ SK+ + ++ E L+ +I + N +I +M+
Sbjct: 651 LEKFLEKINEMKEEFKIENE---KGRVESKT------RGITIETLDLQIKKINERIHQMK 701
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDF 215
M K KT ALGTSKINY+DPR+T AWC ++ V IE++F K+L F WA D+
Sbjct: 702 ALMIDKAQNKTTALGTSKINYIDPRLTYAWCAKYGVNIERVFTKTLRETFAWAASTTADW 761
Query: 214 RF 209
F
Sbjct: 762 EF 763
[191][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 82.8 bits (203), Expect = 2e-14
Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +KLD++ + KE + +L + GKP KN + E L+++I +I +
Sbjct: 666 IKDKLDKIDELEKEYQKEL---KTGKPIVT-------KNATVEKLKQQIETLENRILNVS 715
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+ V + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 716 IQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPIEKLFTKTLREKFIWAIESADEN 775
Query: 217 FRF 209
+RF
Sbjct: 776 WRF 778
[192][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 82.4 bits (202), Expect = 2e-14
Identities = 46/117 (39%), Positives = 70/117 (59%), Gaps = 3/117 (2%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R +L A+ + D K KK + S+ +K + + ++ K++
Sbjct: 666 LQGKIDAKKDQLMDARRELKSAKADAKVKR--DEKSKKLVESK--KKAVQRVEEQLMKLE 721
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK---SLLAKFTWAM 233
+E+ K +ALGTSK+NYLDPRI+VAWCK++ +PIEKI+NK SLL W M
Sbjct: 722 VQATDREENKQIALGTSKLNYLDPRISVAWCKKYGIPIEKIYNKTQRSLLGPLIWRM 778
[193][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 82.4 bits (202), Expect = 2e-14
Identities = 38/83 (45%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -2
Query: 454 SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
S E ++ ++ + +I+ +K KE+ V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 663 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 722
Query: 274 IFNKSLLAKFTWAMD-VDPDFRF 209
IF K+L KF WA++ VD ++RF
Sbjct: 723 IFTKTLREKFKWAIESVDENWRF 745
[194][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 82.4 bits (202), Expect = 2e-14
Identities = 38/83 (45%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -2
Query: 454 SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
S E ++ ++ + +I+ +K KE+ V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 274 IFNKSLLAKFTWAMD-VDPDFRF 209
IF K+L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[195][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 82.4 bits (202), Expect = 2e-14
Identities = 38/83 (45%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -2
Query: 454 SSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
S E ++ ++ + +I+ +K KE+ V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 274 IFNKSLLAKFTWAMD-VDPDFRF 209
IF K+L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[196][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 82.0 bits (201), Expect = 3e-14
Identities = 46/123 (37%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK++++ + KE +L + GKP + KK+++ E L+ ++ +I
Sbjct: 677 LEEKMEKVNELEKEYAEEL---KTGKP-------QIKKSVTVEKLKSQVDTLTNRILNTT 726
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ VPIEK+F K+L KF WA++ D +
Sbjct: 727 FQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNVPIEKLFTKTLRDKFNWAIESADEN 786
Query: 217 FRF 209
++F
Sbjct: 787 WKF 789
[197][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 82.0 bits (201), Expect = 3e-14
Identities = 44/123 (35%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + + + +L A+K +S +K N E+ ++ + + ++ +M+
Sbjct: 385 LKSKIDAKKEQILLAKKELKEAKKEAKEKES----EKLNKVVESKKRGVQRAEEQLMRME 440
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPD 218
+E+ K +AL TSK+NYLDPRI+VAWCK+ V +EKI+NK+ KF WA+D+ + D
Sbjct: 441 VQATDREENKQIALSTSKLNYLDPRISVAWCKKWTVGLEKIYNKTYRDKFAWAVDMTETD 500
Query: 217 FRF 209
F F
Sbjct: 501 FIF 503
[198][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 82.0 bits (201), Expect = 3e-14
Identities = 43/110 (39%), Positives = 70/110 (63%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ K D++ + K+++ A++G K KKKK+L +++ + K+E +
Sbjct: 128 IGTKRDQIAEMEKQVKDAQKDAKRGSVKEKVVYDKKKKHL------ERLREQLVKLEVAE 181
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
D +++ K++ALGTSK+NYLDPRITVAWCK++ VPIEK++NK+ KF
Sbjct: 182 TD---RDENKSIALGTSKLNYLDPRITVAWCKKYGVPIEKVYNKTQRDKF 228
[199][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 82.0 bits (201), Expect = 3e-14
Identities = 46/123 (37%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK++++ + KE +L + GKP + KK+++ E L+ ++ +I
Sbjct: 677 LEEKMEKVNELEKEYAEEL---KTGKP-------QIKKSVTVEKLKSQVDTLTNRILNTT 726
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ VPIEK+F K+L KF WA++ D +
Sbjct: 727 FQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNVPIEKLFTKTLRDKFNWAIESADEN 786
Query: 217 FRF 209
++F
Sbjct: 787 WKF 789
[200][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 82.0 bits (201), Expect = 3e-14
Identities = 47/123 (38%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K++ +A + E + +L +A D K K L + K+ + A++
Sbjct: 476 LQKKIETKKAQVAEAQVELQKAETDL--RMRGDSKSKSFLQKQQRLLKLEEQLARLCTKA 533
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
D KE+ K VALGT+K+NYLDPRI++AWCKR VP+EKI+NK+ +F WA + D
Sbjct: 534 TD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGED 590
Query: 217 FRF 209
F F
Sbjct: 591 FEF 593
[201][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 81.6 bits (200), Expect = 4e-14
Identities = 47/123 (38%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K++ +A + E + +L +A D K K L + K+ + A++
Sbjct: 178 LQKKIETKKAQVAEAQVELQKAETDL--RMRGDSKPKSFLQKQRRLLKLEEQLARLCAKA 235
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
D KE+ K VALGT+K+NYLDPRI++AWCKR VP+EKI+NK+ +F WA + D
Sbjct: 236 TD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGED 292
Query: 217 FRF 209
F F
Sbjct: 293 FEF 295
[202][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 81.6 bits (200), Expect = 4e-14
Identities = 47/123 (38%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K++ +A + E + +L +A D K K L + K+ + A++
Sbjct: 475 LQKKIETKKAQVAEAQVELQKAETDL--RMRGDSKPKSFLQKQRRLLKLEEQLARLCAKA 532
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
D KE+ K VALGT+K+NYLDPRI++AWCKR VP+EKI+NK+ +F WA + D
Sbjct: 533 TD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGED 589
Query: 217 FRF 209
F F
Sbjct: 590 FEF 592
[203][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 81.6 bits (200), Expect = 4e-14
Identities = 45/108 (41%), Positives = 70/108 (64%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E+++E Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQIEEAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[204][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 81.6 bits (200), Expect = 4e-14
Identities = 45/108 (41%), Positives = 69/108 (63%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++ + Q +K+ + D A+ G K KKKK L +++ + K+E M+ D
Sbjct: 151 EQITDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKTL------ERLKEQLMKLEVMETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[205][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 81.6 bits (200), Expect = 4e-14
Identities = 49/122 (40%), Positives = 71/122 (58%), Gaps = 6/122 (4%)
Frame = -2
Query: 556 ELQAVLKELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQR 392
E + KEL L A + + K + KK + + E E +IS+ + +IE M
Sbjct: 775 EKEMKAKELEERLKAADELEAKYKKENKTKKVEAEGRGPTVEKFEGQISKIDQRIENMLL 834
Query: 391 DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPDF 215
+ KE+ K VALGTSK+NY+DPR+TV + K+ VPIEK F+K++ KF WA+ VD D+
Sbjct: 835 QAEDKENNKEVALGTSKLNYIDPRLTVVFSKKFNVPIEKFFSKTMREKFDWAIKSVDEDW 894
Query: 214 RF 209
F
Sbjct: 895 EF 896
[206][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 81.6 bits (200), Expect = 4e-14
Identities = 47/115 (40%), Positives = 70/115 (60%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
LNE+L + TDL++ K + SK + + K + S E E I++ + +I M
Sbjct: 796 LNERL--------QAATDLEKKFKKENKSKKVEAEGKGS-SVEKFEANITKIDERIANML 846
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
+ +E K VALGTSKINY+DPR+TV + ++ +VPIEK F+K+L KF WA+D
Sbjct: 847 LKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVPIEKFFSKTLREKFAWAID 901
[207][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 81.6 bits (200), Expect = 4e-14
Identities = 47/123 (38%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K++ +A + E + +L +A D K K L + K+ + A++
Sbjct: 476 LQKKIETKKAQVAEAQVELQKAETDL--RMRGDSKPKSFLQKQRRLLKLEEQLARLCAKA 533
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
D KE+ K VALGT+K+NYLDPRI++AWCKR VP+EKI+NK+ +F WA + D
Sbjct: 534 TD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGED 590
Query: 217 FRF 209
F F
Sbjct: 591 FEF 593
[208][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 81.3 bits (199), Expect = 5e-14
Identities = 45/105 (42%), Positives = 62/105 (59%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+DE Q L R L A+ S D K KK + E K + + ++ K+Q
Sbjct: 687 LQTKIDEKQKQLSAARKQLKAAKAEHKASH--DDKSKKAV--EVKRKAVQRIEEQLMKLQ 742
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 260
+E+ K +ALGTSK+NYLDPRI+VAWCK+ +PIEKI+NK+
Sbjct: 743 VQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKT 787
[209][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 81.3 bits (199), Expect = 5e-14
Identities = 44/108 (40%), Positives = 71/108 (65%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++++ Q +K+ + D A+ G K KKKK L +++ + K+E ++ D
Sbjct: 151 EQIEDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVLETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[210][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 81.3 bits (199), Expect = 5e-14
Identities = 46/114 (40%), Positives = 69/114 (60%), Gaps = 4/114 (3%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLD----RARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKI 407
L EK+++ + + E+ + A++G K KKKK L +K+ K+
Sbjct: 176 LKEKIEQKKDTISEMERQVQDAQRAAKRGSVKEKVVYDKKKKAL------EKLKDQLVKL 229
Query: 406 EKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
E + D K++ K++ALGTSK+NYLDPRI+VAWCK++ VPIEKI+NK+ KF
Sbjct: 230 EVQETD---KDENKSIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKF 280
[211][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 81.3 bits (199), Expect = 5e-14
Identities = 40/110 (36%), Positives = 67/110 (60%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ EK+D + +K+ + A++ + G K+ E K + + ++ K++
Sbjct: 142 IKEKIDAKRQAIKDAERQVKDAQRD-----AKHGSVKEKTVYEKKRKLLERLKEQLTKLE 196
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ KT+ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 197 IQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIYNKTQRDKF 246
[212][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 81.3 bits (199), Expect = 5e-14
Identities = 47/123 (38%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ EK+D++ + KE + + + GKP KN + E L+ +I +I
Sbjct: 665 IKEKMDKITELEKEYKQE---RKTGKPVVP-------KNATVEKLKGQIETLENRILTTS 714
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD-VDPD 218
+K KED V+LGTSK+NY+DPR+TV + K+ +VPIEK+F K+L KF WA++ D +
Sbjct: 715 FQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVPIEKLFTKTLRDKFKWAIESTDEN 774
Query: 217 FRF 209
+RF
Sbjct: 775 WRF 777
[213][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 80.9 bits (198), Expect = 7e-14
Identities = 39/110 (35%), Positives = 71/110 (64%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+D+ + + +++ + A+K + G K+ + + +K + + ++ K++
Sbjct: 176 LKEKIDQKKENITDMQRQVKDAQKD-----AKHGSVKEKVVYDKKKKALERLRDQLMKLE 230
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 231 VQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 280
[214][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 80.5 bits (197), Expect = 9e-14
Identities = 44/108 (40%), Positives = 70/108 (64%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++++ Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQIEDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[215][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 80.5 bits (197), Expect = 9e-14
Identities = 43/110 (39%), Positives = 69/110 (62%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+++K +++ K+++ A+ G K KKKK L +K+ + K+E +
Sbjct: 146 IDQKREQITDAQKQVKDAQRDAKHGSVKEKVVYDKKKKML------EKLKEQLIKLEVQE 199
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
D +++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 200 TD---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[216][TOP]
>UniRef100_Q8TBP3 TOP1MT protein (Fragment) n=1 Tax=Homo sapiens RepID=Q8TBP3_HUMAN
Length = 101
Score = 80.1 bits (196), Expect = 1e-13
Identities = 46/108 (42%), Positives = 66/108 (61%), Gaps = 4/108 (3%)
Frame = -2
Query: 520 LDRAR---KGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALG 350
L RAR K + KS +KK E L+++++Q + + KE+ K VALG
Sbjct: 1 LRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATD-------KEENKQVALG 53
Query: 349 TSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
TSK+NYLDPRI++AWCKR VP+EKI++K+ +F WA+ + DF F
Sbjct: 54 TSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 101
[217][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 79.7 bits (195), Expect = 1e-13
Identities = 40/94 (42%), Positives = 61/94 (64%), Gaps = 7/94 (7%)
Frame = -2
Query: 469 KKKNLSSEALEKKISQTNAKIEKMQRDMKT------KEDLKTVALGTSKINYLDPRITVA 308
K K S L+ + + A +++ ++ +K +E+ K +ALGTSK+NYLDPRI+VA
Sbjct: 599 KAKGSSEFKLQTLVERKKAAVKRCEQLLKMEIQATDREENKQIALGTSKLNYLDPRISVA 658
Query: 307 WCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 209
WCK +P++KI+NKS KF WA+D+ + DF F
Sbjct: 659 WCKNMGLPVDKIYNKSQRDKFAWAIDMTEVDFEF 692
[218][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 79.7 bits (195), Expect = 1e-13
Identities = 43/115 (37%), Positives = 69/115 (60%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EKL ++ + E + +L + KP KS ++ E LE ++ + +I
Sbjct: 650 LEEKLKKIDELAAEYKKEL---KTRKPEIKSV------TVTVEKLESQVEKLEQRIRNAT 700
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
++ KED VALGTSK+NY+DPR+T + K+++VPIEK+F+K+L KF WA++
Sbjct: 701 LLLQDKEDNSQVALGTSKLNYIDPRLTAMFSKKYDVPIEKLFSKTLREKFAWAIE 755
[219][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 79.3 bits (194), Expect = 2e-13
Identities = 44/108 (40%), Positives = 69/108 (63%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++ + Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQITDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[220][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 79.3 bits (194), Expect = 2e-13
Identities = 44/108 (40%), Positives = 68/108 (62%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++ + Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQITDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTXRDKF 246
[221][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 79.3 bits (194), Expect = 2e-13
Identities = 42/110 (38%), Positives = 68/110 (61%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +K D + ++++ A++G K KKKK L +++ K+E +
Sbjct: 146 IEQKKDAISDAEQQVKDAQRDAKRGSVKEKVVYDKKKKTL------ERLKDQLMKLEVQE 199
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
D +++ K++ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 200 TD---RDENKSIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKAQRDKF 246
[222][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/110 (38%), Positives = 68/110 (61%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +K +++ K+++ A+ G K KKKK L +++ + K+E +
Sbjct: 146 IEQKREQIVDAQKQVKDAQRDAKHGSVKEKVVYDKKKKML------ERLKEQLVKLEVQE 199
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
D +++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 200 TD---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[223][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 79.0 bits (193), Expect = 2e-13
Identities = 44/108 (40%), Positives = 68/108 (62%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++ + Q +K+ + D A+ G K KKKK L +++ + K+E + D
Sbjct: 151 EQITDAQKQVKDAQRD---AKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQETD 201
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
+++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 202 ---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRHKF 246
[224][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 79.0 bits (193), Expect = 2e-13
Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 5/107 (4%)
Frame = -2
Query: 538 KELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQRDMKTKE 374
KEL+ L A + K + KK + ++ E LE+++ + + +I M+ ++
Sbjct: 789 KELKERLKAASEMDAMYKKENKTKKVLAEGRGVTVEKLEQQVKKLDERIRTMELQAADRD 848
Query: 373 DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
K VALGTSKINY+DPR+TV +C + VPIEK F+K+L KF WA+
Sbjct: 849 GNKEVALGTSKINYIDPRLTVVFCNKMNVPIEKFFSKTLREKFNWAI 895
[225][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 78.6 bits (192), Expect = 3e-13
Identities = 42/110 (38%), Positives = 68/110 (61%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
+ +K +++ K+++ A+ G K KKKK L +++ + K+E +
Sbjct: 146 IEQKREQIVDAQKQVKDAQRDAKHGSVKEKVVYDKKKKML------ERLKEQLIKLEVQE 199
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 245
D +++ K +ALGTSK+NYLDPRI+VAWCK+++VPIEKI+NK+ KF
Sbjct: 200 TD---RDENKAIALGTSKLNYLDPRISVAWCKKYDVPIEKIYNKTQRDKF 246
[226][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 77.8 bits (190), Expect = 6e-13
Identities = 41/99 (41%), Positives = 63/99 (63%)
Frame = -2
Query: 526 TDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGT 347
TDL++ K + +K + + K S + E I++ + +I M + +E K VALGT
Sbjct: 805 TDLEKKFKKENKTKKVEAEGK-GPSVDKFEANITKIDERIANMLLKREDREGNKEVALGT 863
Query: 346 SKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
SKINY+DPR+TV + ++ +VPIEK F+K+L KF WA+D
Sbjct: 864 SKINYIDPRLTVVFSQKFDVPIEKFFSKTLREKFAWAID 902
[227][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
Length = 904
Score = 76.6 bits (187), Expect = 1e-12
Identities = 44/108 (40%), Positives = 65/108 (60%), Gaps = 5/108 (4%)
Frame = -2
Query: 538 KELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQRDMKTKE 374
KEL+ L A + + K + KK K + E LE +S+ + +I+ ++ +E
Sbjct: 787 KELKERLRVAAELEAKYKKENKTKKVEAEGKGPAVEKLEAAVSKFDDRIKTLELQCADRE 846
Query: 373 DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
K VALGTSKINY+DPR+TV + K+ VPIEK F+K+L KF WA++
Sbjct: 847 GNKEVALGTSKINYIDPRLTVVFAKKFNVPIEKFFSKTLRDKFKWAIE 894
[228][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 76.3 bits (186), Expect = 2e-12
Identities = 41/105 (39%), Positives = 65/105 (61%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L K+D + L + R + A+ + D K KK + S+ +K + + ++ K++
Sbjct: 703 LQGKIDAKKDQLADARREFKSAKADAKVRR--DEKTKKLVESK--KKAVQRIEEQLMKLE 758
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 260
+E+ K +ALGTSK+NYLDPRI+VAWCK++ VPIEKI+NK+
Sbjct: 759 VQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKT 803
[229][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 75.5 bits (184), Expect = 3e-12
Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 8/121 (6%)
Frame = -2
Query: 571 NEKLD-ELQAVL--KELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTN 416
NEKL+ + QA L KEL+ L + + K + KK K S E L + + +
Sbjct: 776 NEKLEADKQAKLPAKELKERLKAVAELEAKFKKENKTKKVEAEGKGPSVEKLTTAVEKLD 835
Query: 415 AKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWA 236
+I ++ +E K VALGTSKINY+DPR+TV + + +VPIEK F+K+L KF WA
Sbjct: 836 ERIRTLEMQSADREGNKEVALGTSKINYIDPRLTVVFSNKFQVPIEKFFSKTLRDKFNWA 895
Query: 235 M 233
+
Sbjct: 896 I 896
[230][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 73.9 bits (180), Expect = 8e-12
Identities = 42/107 (39%), Positives = 62/107 (57%), Gaps = 5/107 (4%)
Frame = -2
Query: 535 ELRTDLDRARKGKPPSKSPDGKKK-----KNLSSEALEKKISQTNAKIEKMQRDMKTKED 371
EL+ L A + + K + KK K S E LE + + + +I+ ++ +E
Sbjct: 758 ELKERLKAASELEAKFKKENKTKKVEAEGKGPSVEKLEAALEKLDQRIKNLELQSADREG 817
Query: 370 LKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMD 230
K VALGTSKINY+DPR+TV + + VPIEK F+K+L KF WA++
Sbjct: 818 NKEVALGTSKINYIDPRLTVVFSAKFNVPIEKFFSKTLREKFKWAIE 864
[231][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 73.6 bits (179), Expect = 1e-11
Identities = 40/112 (35%), Positives = 64/112 (57%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
++L E V+KEL + K K G + + K I + + +++ ++
Sbjct: 802 KELKERLQVVKELEAKFKKENKTKKVEAEGRGP-----TVDKFIKAIEKLDERVKVLETQ 856
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
+ ++ K VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L KF WA+
Sbjct: 857 AEDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAI 908
[232][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 73.2 bits (178), Expect = 1e-11
Identities = 39/112 (34%), Positives = 64/112 (57%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
++L E V+KE+ + K K G + + K + + + +I+ ++
Sbjct: 793 KELKERLQVVKEMEAKFKKENKSKKVEAEGRGA-----TVDKFLKAVDKFDERIKTLELQ 847
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
+ ++ K VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L KF WA+
Sbjct: 848 AQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAI 899
[233][TOP]
>UniRef100_Q38EP5 DNA topoisomerase type IB small subunit n=1 Tax=Trypanosoma brucei
RepID=Q38EP5_9TRYP
Length = 273
Score = 73.2 bits (178), Expect = 1e-11
Identities = 39/100 (39%), Positives = 60/100 (60%), Gaps = 2/100 (2%)
Frame = -2
Query: 502 GKPPSKSPDGKKKKNLSS--EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYL 329
GKPP + K L S +E +I + +++ ++ +K K+D KTV+LGTSK+NY+
Sbjct: 182 GKPP-------RPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYI 234
Query: 328 DPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
DPRI +W + VPI ++F+ +L KF WA+ DF F
Sbjct: 235 DPRIVCSWANENNVPISRLFSATLQKKFPWALKA-RDFTF 273
[234][TOP]
>UniRef100_C9ZXZ7 DNA topoisomerase type IB small subunit, putative n=2
Tax=Trypanosoma brucei RepID=C9ZXZ7_TRYBG
Length = 273
Score = 73.2 bits (178), Expect = 1e-11
Identities = 39/100 (39%), Positives = 60/100 (60%), Gaps = 2/100 (2%)
Frame = -2
Query: 502 GKPPSKSPDGKKKKNLSS--EALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYL 329
GKPP + K L S +E +I + +++ ++ +K K+D KTV+LGTSK+NY+
Sbjct: 182 GKPP-------RPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYI 234
Query: 328 DPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 209
DPRI +W + VPI ++F+ +L KF WA+ DF F
Sbjct: 235 DPRIVCSWANENNVPISRLFSATLQKKFPWALKA-RDFTF 273
[235][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 73.2 bits (178), Expect = 1e-11
Identities = 40/101 (39%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
Frame = -2
Query: 568 EKLDE-LQAVLKELRTDLDRARKGKPP--SKSPDGKKKKNLSSEALEKKISQTNAKIEKM 398
E+LDE L + KEL + + +K K ++ D K + L++K+ + ++ K
Sbjct: 2291 ERLDEALVKIQKELDSTIKERKKLKKDLRAQGSDVSKTDLNRLDVLKRKVDRLEERLHKK 2350
Query: 397 QRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK 275
Q KE+ K +AL TSK+NYLDPRI+VAWCK H+VP++K
Sbjct: 2351 QIAKVDKEENKCIALSTSKLNYLDPRISVAWCKTHDVPVDK 2391
[236][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 73.2 bits (178), Expect = 1e-11
Identities = 39/112 (34%), Positives = 64/112 (57%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
++L E V+KE+ + K K G + + K + + + +I+ ++
Sbjct: 792 KELKERLQVVKEMEAKFKKENKSKKVEAEGRGA-----TVDKFLKAVDKFDERIKTLELQ 846
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
+ ++ K VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L KF WA+
Sbjct: 847 AQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTLRDKFRWAI 898
[237][TOP]
>UniRef100_Q95Z89 Possible DNA topoisomerase I-related protein n=1 Tax=Leishmania
major RepID=Q95Z89_LEIMA
Length = 262
Score = 72.8 bits (177), Expect = 2e-11
Identities = 40/107 (37%), Positives = 61/107 (57%)
Frame = -2
Query: 544 VLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLK 365
V KE+ T + P + P + N +ALE+ + N + + ++ K+D K
Sbjct: 156 VNKEILTQEEEEVPTLVPPRPPVVRSFPNDIGKALERYRERLNRE----ENIIRIKDDNK 211
Query: 364 TVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVD 224
V+LGTSKINY+DPRI +W K +VPI KIF+ ++ KF WAM+ +
Sbjct: 212 AVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNAE 258
[238][TOP]
>UniRef100_Q70HS8 DNA topoisomerase I subunit B (Fragment) n=1 Tax=Leishmania
panamensis RepID=Q70HS8_9TRYP
Length = 269
Score = 72.8 bits (177), Expect = 2e-11
Identities = 30/71 (42%), Positives = 49/71 (69%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K + + ++ + + ++ K+D K V+LGTSKINY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 256 LAKFTWAMDVD 224
L KF WAM+ +
Sbjct: 255 LKKFPWAMNAE 265
[239][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 72.8 bits (177), Expect = 2e-11
Identities = 32/62 (51%), Positives = 47/62 (75%)
Frame = -2
Query: 472 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRH 293
K K+N+ E+ +KK+ K+E ++ MK ++D KT+ALGTSKINY+DPRITVA+CK+
Sbjct: 744 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 803
Query: 292 EV 287
E+
Sbjct: 804 EI 805
[240][TOP]
>UniRef100_Q8WQM6 DNA topoisomerase I-like protein n=1 Tax=Leishmania donovani
RepID=Q8WQM6_LEIDO
Length = 262
Score = 72.4 bits (176), Expect = 2e-11
Identities = 40/107 (37%), Positives = 61/107 (57%)
Frame = -2
Query: 544 VLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLK 365
V KE+ T + P + P + N +ALE+ + N + + ++ K+D K
Sbjct: 156 VNKEVLTQEEEEVPTLVPPRPPVVRSFPNDIGKALERYRERLNRE----ENIIRIKDDNK 211
Query: 364 TVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVD 224
V+LGTSKINY+DPRI +W K +VPI KIF+ ++ KF WAM+ +
Sbjct: 212 AVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNAE 258
[241][TOP]
>UniRef100_A4H3S7 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania
braziliensis RepID=A4H3S7_LEIBR
Length = 269
Score = 72.4 bits (176), Expect = 2e-11
Identities = 30/71 (42%), Positives = 48/71 (67%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K + + ++ + + ++ K+D K V+LGTSKINY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 256 LAKFTWAMDVD 224
L KF WAM +
Sbjct: 255 LKKFPWAMSAE 265
[242][TOP]
>UniRef100_Q4DUD0 DNA topoisomerase type IB small subunit, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DUD0_TRYCR
Length = 272
Score = 71.2 bits (173), Expect = 5e-11
Identities = 36/91 (39%), Positives = 54/91 (59%)
Frame = -2
Query: 496 PPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRI 317
PP + P + N AL++ + N + + ++ K+D K V+LGTSK+NY+DPRI
Sbjct: 182 PPPRPPIVRSFPNNVDLALQRYEERLNRE----ENMIRIKDDNKAVSLGTSKVNYIDPRI 237
Query: 316 TVAWCKRHEVPIEKIFNKSLLAKFTWAMDVD 224
+W K + VPI KIF+ +L KF WAM +
Sbjct: 238 VCSWAKEYNVPIGKIFSATLQKKFPWAMGAE 268
[243][TOP]
>UniRef100_A4HS02 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania infantum
RepID=A4HS02_LEIIN
Length = 262
Score = 71.2 bits (173), Expect = 5e-11
Identities = 30/71 (42%), Positives = 48/71 (67%)
Frame = -2
Query: 436 KKISQTNAKIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 257
K + + ++ + + ++ K+D K V+LGTSKINY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 256 LAKFTWAMDVD 224
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[244][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 70.5 bits (171), Expect = 9e-11
Identities = 40/96 (41%), Positives = 60/96 (62%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E++ E+Q +K+ + D A+ G K KKKK L +++ K+E + D
Sbjct: 185 EQITEMQKQVKDAQRD---AQHGSVKEKVVLDKKKKGL------ERLKDQLVKLEVQETD 235
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 281
K++ K++ALGTSK+NYLDPRI+VAWCK++EVPI
Sbjct: 236 ---KDENKSIALGTSKLNYLDPRISVAWCKKYEVPI 268
[245][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 70.1 bits (170), Expect = 1e-10
Identities = 44/118 (37%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
++L E EL T L + K K + L A KKI + +E +D
Sbjct: 775 KELKERLKAASELLTKLKKEHKTKKVEAEGRSPTVEKLLEGA--KKIEERAKNLELQAQD 832
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM-DVDPD 218
++ K VALGTSK+NY+DPR+TV + ++ +VPIEK F+K++ KF WA+ VD D
Sbjct: 833 ---RDGNKEVALGTSKLNYIDPRLTVVFSRKFDVPIEKFFSKTMREKFNWAIQSVDDD 887
[246][TOP]
>UniRef100_Q5RL92 Type IB topoisomerase small subunit n=1 Tax=Trypanosoma cruzi
RepID=Q5RL92_TRYCR
Length = 271
Score = 69.3 bits (168), Expect = 2e-10
Identities = 29/63 (46%), Positives = 44/63 (69%)
Frame = -2
Query: 412 KIEKMQRDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 233
++ + + ++ K+D K V+LGTSK+NY+DPRI +W K + VPI KIF+ +L KF WAM
Sbjct: 205 RLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWAM 264
Query: 232 DVD 224
+
Sbjct: 265 GAE 267
[247][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/98 (32%), Positives = 62/98 (63%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+++ + + E++ + A K + G K+ + + +K + + +++K++
Sbjct: 142 LKEKIEQKKEHIAEMQKQVKDAAKD-----AKHGSVKEKVVHDKKKKALERLKDQLKKLE 196
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 281
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPI
Sbjct: 197 VQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234
[248][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/98 (32%), Positives = 62/98 (63%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L EK+++ + ++E++ + A K + G K+ + + +K + + ++ K++
Sbjct: 142 LKEKIEQKREFIQEMQKXVKDAAKD-----AKHGSVKEKVVHDKKKKALERLRDQLMKLE 196
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 281
+++ K++ALGTSK+NYLDPRI+VAWCK+++VPI
Sbjct: 197 VQETDRDENKSIALGTSKLNYLDPRISVAWCKKYDVPI 234
[249][TOP]
>UniRef100_B7QCX5 DNA topoisomerase type I, putative (Fragment) n=1 Tax=Ixodes
scapularis RepID=B7QCX5_IXOSC
Length = 250
Score = 65.5 bits (158), Expect = 3e-09
Identities = 35/91 (38%), Positives = 59/91 (64%)
Frame = -2
Query: 574 LNEKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQ 395
L +K++E +A ++E + +L + + S+S +K K L E +K++ Q +++K++
Sbjct: 164 LQKKMEEKEAQIRECKKELKQHKSDYNNSRS---EKDKQLL-ERKKKRMQQLEDQMKKLE 219
Query: 394 RDMKTKEDLKTVALGTSKINYLDPRITVAWC 302
KE+ K +ALGTSK+NYLDPRI+VAWC
Sbjct: 220 VQATDKEENKQIALGTSKLNYLDPRISVAWC 250
[250][TOP]
>UniRef100_B3GD27 Topoisomerase I (Fragment) n=1 Tax=Macrogyrus oblongus
RepID=B3GD27_9COLE
Length = 263
Score = 65.5 bits (158), Expect = 3e-09
Identities = 37/91 (40%), Positives = 57/91 (62%)
Frame = -2
Query: 568 EKLDELQAVLKELRTDLDRARKGKPPSKSPDGKKKKNLSSEALEKKISQTNAKIEKMQRD 389
E+++E+Q +K+ + D AR G K KKKK L +K+ + ++E + D
Sbjct: 185 EQINEMQRQVKDAQRD---ARNGSVKEKMVFDKKKKAL------EKLKEQMIRLEVQETD 235
Query: 388 MKTKEDLKTVALGTSKINYLDPRITVAWCKR 296
K++ K++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 236 ---KDENKSIALGTSKLNYLDPRISVAWCKK 263