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[1][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 150 bits (380), Expect = 5e-35
Identities = 76/95 (80%), Positives = 81/95 (85%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EK
Sbjct: 246 RMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEK 305
Query: 378 SALAILKNLGLIEETSIPRT----RPANAIQAKED 286
SALAIL NLGLIEE+ I R P N +AKED
Sbjct: 306 SALAILMNLGLIEESKITRALPWRPPTNVFRAKED 340
[2][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 150 bits (380), Expect = 5e-35
Identities = 74/95 (77%), Positives = 83/95 (87%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP E+MAALEPIKDNEEAVKAYGIHLGTEMCKK+LAHG K+LHLYTLN+EK
Sbjct: 232 RMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SALAIL NLG+I+E+ S+P RPAN + KED
Sbjct: 292 SALAILMNLGMIDESKISRSLPWRRPANVFRTKED 326
[3][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 149 bits (376), Expect = 1e-34
Identities = 74/95 (77%), Positives = 81/95 (85%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EK
Sbjct: 232 RMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEK 291
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKED 286
SALAIL NLGLIEE+ I P RP N + KED
Sbjct: 292 SALAILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
[4][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 149 bits (376), Expect = 1e-34
Identities = 74/95 (77%), Positives = 81/95 (85%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT+HLYTLN+EK
Sbjct: 232 RMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEK 291
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKED 286
SALAIL NLGLIEE+ I P RP N + KED
Sbjct: 292 SALAILMNLGLIEESKISRPFPWRRPTNVFRVKED 326
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 147 bits (370), Expect = 7e-34
Identities = 74/95 (77%), Positives = 79/95 (83%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EK
Sbjct: 243 RMAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEK 302
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKED 286
SALAIL NLGLIEE+ I P P N + KED
Sbjct: 303 SALAILMNLGLIEESKITRPLPWRPPTNVFRVKED 337
[6][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 146 bits (368), Expect = 1e-33
Identities = 74/95 (77%), Positives = 80/95 (84%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPAEI AAL+PIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK
Sbjct: 220 RMTGFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEK 279
Query: 378 SALAILKNLGLIEETSIPRT----RPANAIQAKED 286
+ALAIL NLGLIEE+ + RT P N + KED
Sbjct: 280 TALAILMNLGLIEESKLSRTLPWRPPTNVFRVKED 314
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 145 bits (367), Expect = 2e-33
Identities = 75/95 (78%), Positives = 79/95 (83%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK
Sbjct: 232 RMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SAL IL NLGLIEE+ S+P P N + KED
Sbjct: 292 SALGILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
[8][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 145 bits (367), Expect = 2e-33
Identities = 73/94 (77%), Positives = 79/94 (84%), Gaps = 4/94 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPAE+ AALEPIKDNEEAV+AYGIHLGTEMCKKI+AHG KTLHLYTLN+EK
Sbjct: 247 RMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLYTLNMEK 306
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKE 289
SALAIL NLGLIEE+ I P P N + KE
Sbjct: 307 SALAILMNLGLIEESKISRPLPWRPPTNVFRVKE 340
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 145 bits (367), Expect = 2e-33
Identities = 75/95 (78%), Positives = 79/95 (83%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPAEI AALEPIKDNEEAVKAYGIHLGTEMCKKILA G KTLHLYTLN+EK
Sbjct: 232 RMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SAL IL NLGLIEE+ S+P P N + KED
Sbjct: 292 SALGILMNLGLIEESKISRSLPWRPPTNVFRVKED 326
[10][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 144 bits (362), Expect = 6e-33
Identities = 72/87 (82%), Positives = 76/87 (87%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIPA+IMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG TLHLYTLN+EK
Sbjct: 233 RMTGFCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEK 292
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQ 298
SALAIL NLGLIEET +A+Q
Sbjct: 293 SALAILMNLGLIEETKFLGPYLGDALQ 319
[11][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 140 bits (354), Expect = 5e-32
Identities = 71/95 (74%), Positives = 78/95 (82%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIP+EI AALEPIKDNEEAV+AYGIHLGTEMCKKILAHG KTLHLYTLN+EK
Sbjct: 232 RMAGFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEK 291
Query: 378 SALAILKNLGLIEETSIPRTRP----ANAIQAKED 286
SAL IL NLGLI+ T I R P N ++ KE+
Sbjct: 292 SALGILANLGLIDMTKIRRPLPWRPATNVLRTKEN 326
[12][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 139 bits (349), Expect = 2e-31
Identities = 68/95 (71%), Positives = 78/95 (82%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++K
Sbjct: 232 RMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[13][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 139 bits (349), Expect = 2e-31
Identities = 68/95 (71%), Positives = 78/95 (82%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++K
Sbjct: 42 RMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDK 101
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 102 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 136
[14][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 139 bits (349), Expect = 2e-31
Identities = 68/95 (71%), Positives = 78/95 (82%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++K
Sbjct: 232 RMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[15][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 139 bits (349), Expect = 2e-31
Identities = 68/95 (71%), Positives = 78/95 (82%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RM GFCKTKIPAE+ AALEPIKDN+EAVKAYGIH TEMCKKILAHG +LHLYTLN++K
Sbjct: 232 RMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDK 291
Query: 378 SALAILKNLGLIEET----SIPRTRPANAIQAKED 286
SA+ IL NLGLI+E+ S+P RPAN + KED
Sbjct: 292 SAIGILMNLGLIDESKISRSLPWRRPANVFRTKED 326
[16][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 138 bits (348), Expect = 2e-31
Identities = 69/95 (72%), Positives = 77/95 (81%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP+EI AAL+PIKDNEEAVK YGIHLGTEMCKKILA G KTLHLYTLN++K
Sbjct: 232 RMTGFCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDK 291
Query: 378 SALAILKNLGLIEETSIPRTRP----ANAIQAKED 286
SA+ IL NLGLIEE+ + R P N + KED
Sbjct: 292 SAIGILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
[17][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 137 bits (345), Expect = 6e-31
Identities = 68/95 (71%), Positives = 77/95 (81%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP+EI AAL+PIKDNEEAV+ YGIHLGTEMCKKILA G KTLHLYTLN++K
Sbjct: 232 RMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDK 291
Query: 378 SALAILKNLGLIEETSIPRTRP----ANAIQAKED 286
SA+ IL NLGLIEE+ + R P N + KED
Sbjct: 292 SAIGILMNLGLIEESKVSRPLPWRPATNVFRVKED 326
[18][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 132 bits (331), Expect = 2e-29
Identities = 66/95 (69%), Positives = 76/95 (80%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMT CKTK+PAEIMAALEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEK
Sbjct: 232 RMTTLCKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEK 291
Query: 378 SALAILKNLGLIE----ETSIPRTRPANAIQAKED 286
S L IL+NLGLI+ +P P N+ + KED
Sbjct: 292 SVLGILQNLGLIDFSRVSRPLPWRPPTNSKRTKED 326
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 131 bits (330), Expect = 3e-29
Identities = 65/95 (68%), Positives = 76/95 (80%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMT CKTK+PAEIMA LEPIKDN+EAV+AYGIHLGTEMCKKILAH +TLHLY+LNLEK
Sbjct: 232 RMTSLCKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEK 291
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKED 286
S L IL+NLGLI+ + + P P N+ + KED
Sbjct: 292 SVLGILQNLGLIDFSKVTRPLPWRPPTNSKRTKED 326
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 115 bits (289), Expect = 2e-24
Identities = 63/95 (66%), Positives = 71/95 (74%), Gaps = 4/95 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMTGFCKTKIP+E+ AALEPIKDN+EAVKAYGIHLGTEMCKKILAHG KT L T++L
Sbjct: 232 RMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTFGL-TMDLP- 289
Query: 378 SALAILKNLGLIEETSI----PRTRPANAIQAKED 286
+NLGLIEE+ I P RP N + KED
Sbjct: 290 -----WQNLGLIEESKISRPFPWRRPTNVFRVKED 319
[21][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 108 bits (269), Expect = 4e-22
Identities = 54/89 (60%), Positives = 68/89 (76%), Gaps = 1/89 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
RMTGFCKTK+PAEI ALE IKDN+EAVKAYGI LG MC+++LA G +H+YTLNLE
Sbjct: 226 RMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLE 285
Query: 381 KSALAILKNLGLIEETSIPRTRPANAIQA 295
KSA+AIL+ LGL++ + + R P + A
Sbjct: 286 KSAVAILEQLGLVDTSRVQRPLPWRHVPA 314
[22][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 80.5 bits (197), Expect = 8e-14
Identities = 40/72 (55%), Positives = 49/72 (68%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMT KTK+P IM LEPIKDN+E VK YG+ L EM K++L G + LH YTLNLE+
Sbjct: 225 RMTTLSKTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLER 284
Query: 378 SALAILKNLGLI 343
S +LK L L+
Sbjct: 285 SVRKVLKGLQLV 296
[23][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 75.9 bits (185), Expect = 2e-12
Identities = 37/72 (51%), Positives = 49/72 (68%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
++T K IP EI +EPIKDN+ A++ YGI L T+MC+ +L G LH+YTLNLE
Sbjct: 239 QLTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYTLNLE 298
Query: 381 KSALAILKNLGL 346
+ + ILKNLGL
Sbjct: 299 TATIQILKNLGL 310
[24][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 73.9 bits (180), Expect = 7e-12
Identities = 35/71 (49%), Positives = 46/71 (64%), Gaps = 1/71 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
+M FCKT++P + A +E IKD+ AVKA+G+ G EMC+ +LA G LH YTLNLE
Sbjct: 306 KMAKFCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFYTLNLE 365
Query: 381 KSALAILKNLG 349
K +L LG
Sbjct: 366 KVVYGVLDALG 376
[25][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 73.9 bits (180), Expect = 7e-12
Identities = 35/48 (72%), Positives = 39/48 (81%)
Frame = -1
Query: 555 MTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK 412
MTGFCKTK+ A ALEPIKDNE+AV YGIHLGTEMCKK+L +G K
Sbjct: 12 MTGFCKTKVTA----ALEPIKDNEKAVNTYGIHLGTEMCKKVLGNGIK 55
[26][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 73.6 bits (179), Expect = 1e-11
Identities = 32/75 (42%), Positives = 52/75 (69%), Gaps = 1/75 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLE 382
R + +C+ +P MA L+P+KD+++AV+ G L +MC+K+L G+ T LH+YT+NLE
Sbjct: 226 RRSSWCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLE 285
Query: 381 KSALAILKNLGLIEE 337
K+ + +L LGL+ E
Sbjct: 286 KACIMVLDRLGLLSE 300
[27][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 72.8 bits (177), Expect = 2e-11
Identities = 35/74 (47%), Positives = 53/74 (71%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLE 382
R +C+ ++P E + LEP+KD+++AV+ G L +MC+KILA G T LHLYT+NLE
Sbjct: 226 RRAKWCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLE 285
Query: 381 KSALAILKNLGLIE 340
+++L IL+ L LI+
Sbjct: 286 RASLMILERLQLID 299
[28][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 72.4 bits (176), Expect = 2e-11
Identities = 32/70 (45%), Positives = 46/70 (65%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 355
KIP M L P+KD++E V+ G+ L EMC+K++A G LH YT+NLEK+ I++
Sbjct: 231 KIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIER 290
Query: 354 LGLIEETSIP 325
LGL++E P
Sbjct: 291 LGLLDENLAP 300
[29][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 71.6 bits (174), Expect = 4e-11
Identities = 38/96 (39%), Positives = 56/96 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL++
Sbjct: 223 RRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ IL LGLI P +P Q+ G +E
Sbjct: 283 ATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
[30][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 71.6 bits (174), Expect = 4e-11
Identities = 38/96 (39%), Positives = 56/96 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + + ALEP+K+++ AV+ G L +MCKKILA G LH YT+NL++
Sbjct: 223 RRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ IL LGLI P +P Q+ G +E
Sbjct: 283 ATKMILDELGLIPSHKTPLQKPLPWRQSLGLGRREE 318
[31][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 71.6 bits (174), Expect = 4e-11
Identities = 36/82 (43%), Positives = 50/82 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R T + K KIP M ALEP+K+++ AVK G L +EMC+K+L +G LH YT+NL +
Sbjct: 223 RRTNWVKCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
S +L+ L L T P +P
Sbjct: 283 STTMVLEELNLKPSTETPLQKP 304
[32][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 71.6 bits (174), Expect = 4e-11
Identities = 34/82 (41%), Positives = 51/82 (62%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K +IP + + ALEP+K+++ AVK G L +MC+++LA G K LH YT+NL +
Sbjct: 223 RRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ A+L+ L LI P RP
Sbjct: 283 ATQAVLEELKLIPSEETPLQRP 304
[33][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 70.9 bits (172), Expect = 6e-11
Identities = 31/71 (43%), Positives = 45/71 (63%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
+MT FCKT++P + ++ IKD+ +AVK +G+ G E+ + +L G K LH YTLNLEK
Sbjct: 245 KMTKFCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKILHFYTLNLEK 304
Query: 378 SALAILKNLGL 346
I LG+
Sbjct: 305 VVYGITDELGI 315
[34][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 70.9 bits (172), Expect = 6e-11
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K +IP E + ALEP+K+++ AVK G L EMC+K+LA G LH YT+NL +
Sbjct: 223 RRANWTKARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ ++L L LI P RP
Sbjct: 283 ATQSVLDELKLIPSEETPLQRP 304
[35][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 70.5 bits (171), Expect = 8e-11
Identities = 31/71 (43%), Positives = 45/71 (63%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R++ C K+P+ +++ LE + DN+EA AYGI TE C ++L G LH+YTLN
Sbjct: 231 RISALCGAKLPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAP 290
Query: 378 SALAILKNLGL 346
S + +LKNL L
Sbjct: 291 STIQVLKNLAL 301
[36][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 70.1 bits (170), Expect = 1e-10
Identities = 37/72 (51%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTL---HLYTLN 388
RMT +C +P EI LEPIKD++EAVK G L EMC++ILA + H YTLN
Sbjct: 249 RMTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKIDGVHFYTLN 308
Query: 387 LEKSALAILKNL 352
LE+SA IL L
Sbjct: 309 LERSATRILMQL 320
[37][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 70.1 bits (170), Expect = 1e-10
Identities = 37/96 (38%), Positives = 55/96 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K ++P M ALEP K+++ AVK G L +EMC+KIL G + LH YT+NL +
Sbjct: 223 RRSNWVKCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
S +L+ L LI + P +P Q+ G +E
Sbjct: 283 STKMVLEELDLIPSSETPLQKPLPWRQSLGLGRREE 318
[38][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 69.7 bits (169), Expect = 1e-10
Identities = 33/82 (40%), Positives = 50/82 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +
Sbjct: 223 RRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ A+L+ L LI P RP
Sbjct: 283 ATQAVLEELKLIPSEETPLQRP 304
[39][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 69.7 bits (169), Expect = 1e-10
Identities = 33/82 (40%), Positives = 50/82 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K +IP + + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +
Sbjct: 223 RRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ A+L+ L LI P RP
Sbjct: 283 ATQAVLEELKLIPSEETPLQRP 304
[40][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 69.3 bits (168), Expect = 2e-10
Identities = 33/71 (46%), Positives = 46/71 (64%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMT FCK++ PA + AA+E D++EA++ + G ++C+ + A G LH YTLNLEK
Sbjct: 256 RMTAFCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAGAPGLHFYTLNLEK 315
Query: 378 SALAILKNLGL 346
LAIL L L
Sbjct: 316 VTLAILDALNL 326
[41][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/69 (47%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L MCK++LA G LH YTLN E + + +
Sbjct: 267 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEV 326
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 327 LKRLGMWNE 335
[42][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + KT IP + + ALEP+K+++ AVK G L +MC++++A G K LH YT+NL +
Sbjct: 223 RRANWTKTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
S +L+ L L P RP
Sbjct: 283 STQLVLEELELTPTAEAPIPRP 304
[43][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/82 (40%), Positives = 50/82 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K K+P+E M ALEP+K+++ AV+ G L MC++++A G K LH YT+NL +
Sbjct: 223 RRSNWTKVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ +LK L L P RP
Sbjct: 283 ATQLVLKELELTPSEDSPIQRP 304
[44][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 68.2 bits (165), Expect = 4e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAI 364
K ++P EI A +EPIKDN+ A++ YGI L MC+++L G + LH YTLN E + + +
Sbjct: 270 KLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGVVSGLHFYTLNREVATVEV 329
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 330 LKRLGIWNE 338
[45][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 68.2 bits (165), Expect = 4e-10
Identities = 30/78 (38%), Positives = 53/78 (67%), Gaps = 1/78 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R T +C+ +P + LEP+KD+++ V+ G L E+C+K+L G+ LH+YT+NLE
Sbjct: 228 RRTQWCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLE 287
Query: 381 KSALAILKNLGLIEETSI 328
K++L IL+ L L++ +++
Sbjct: 288 KASLMILEKLDLLKRSNV 305
[46][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 67.8 bits (164), Expect = 5e-10
Identities = 36/96 (37%), Positives = 54/96 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL++
Sbjct: 223 RRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L LGLI P +P Q+ G +E
Sbjct: 283 ATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[47][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 67.8 bits (164), Expect = 5e-10
Identities = 36/96 (37%), Positives = 54/96 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL++
Sbjct: 223 RRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L LGLI P +P Q+ G +E
Sbjct: 283 ATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[48][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 67.8 bits (164), Expect = 5e-10
Identities = 36/96 (37%), Positives = 54/96 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + ALEP+K+++ AV+ G L MCKK+LA G LH YT+NL++
Sbjct: 223 RRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L LGLI P +P Q+ G +E
Sbjct: 283 ATKMVLDELGLIPSHETPLQKPLPWRQSLGLGRREE 318
[49][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 363 LKNLGLIEE 337
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[50][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 363 LKNLGLIEE 337
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[51][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 67.4 bits (163), Expect = 7e-10
Identities = 32/69 (46%), Positives = 46/69 (66%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EIM +EPIKDN+ A++ YGI L MC+++L G LH YTLN E + + +
Sbjct: 267 KLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDV 326
Query: 363 LKNLGLIEE 337
LK LG+ +E
Sbjct: 327 LKRLGMWKE 335
[52][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 67.4 bits (163), Expect = 7e-10
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLY 397
+MT FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH Y
Sbjct: 197 KMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFY 256
Query: 396 TLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 265
TLNLE S I++ L +++ R P +A E RP
Sbjct: 257 TLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
[53][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 67.4 bits (163), Expect = 7e-10
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFK------TLHLY 397
+MT FCKTK+P I LE +K +++ VK G+ + MC +I+++G LH Y
Sbjct: 197 KMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGVDHTHSSGGLHFY 256
Query: 396 TLNLEKSALAILKNLGLIEETSIPRTRPANAIQAKEDGENQERP 265
TLNLE S I++ L +++ R P +A E RP
Sbjct: 257 TLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP 300
[54][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 67.4 bits (163), Expect = 7e-10
Identities = 37/95 (38%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILK 358
KIP + LEP+KD+++ V+ G L +MC+KIL G+ K LH+YT+NLEK+ L IL+
Sbjct: 236 KIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILE 295
Query: 357 NLGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 253
LGL+ S P ++ ++ N +R E++
Sbjct: 296 KLGLLPSESEVNANPLASLPWRK-SLNPKRKNEEV 329
[55][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 67.0 bits (162), Expect = 9e-10
Identities = 33/69 (47%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI EMCK +LA G LH YTLN E + + +
Sbjct: 273 KLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEV 332
Query: 363 LKNLGLIEE 337
L+ LGL E
Sbjct: 333 LRQLGLWAE 341
[56][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 67.0 bits (162), Expect = 9e-10
Identities = 30/72 (41%), Positives = 43/72 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R C K+PA+ + L+ + ++EAV AYGI TE C +L G LH YTLN +
Sbjct: 224 RFVSLCGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKAR 283
Query: 378 SALAILKNLGLI 343
S + I++NLGL+
Sbjct: 284 STVQIVRNLGLL 295
[57][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/69 (47%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 364
K ++P EI + LEPIKDN+ A++ YGI L EMC+ +L G LH YTLN E + + +
Sbjct: 277 KLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 363 LKNLGLIEE 337
L+ LGL E
Sbjct: 337 LRQLGLWTE 345
[58][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/82 (40%), Positives = 48/82 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL +
Sbjct: 223 RRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ +L+ L LI P +P
Sbjct: 283 ATKMVLEELKLIPSYETPLQKP 304
[59][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/82 (40%), Positives = 48/82 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K K+P M ALEP+K+++ AVK G L MC+KIL G + LH YT+NL +
Sbjct: 223 RRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ +L+ L LI P +P
Sbjct: 283 ATKMVLEELKLIPSYETPLQKP 304
[60][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/84 (39%), Positives = 53/84 (63%), Gaps = 2/84 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + KT+IP + + ALEP+K+++ AV+ G L +MC++++A G LH YT+NL +
Sbjct: 223 RRSDWTKTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLI--EETSIPRTRP 313
S +L L L+ EET + R P
Sbjct: 283 STQLVLDELNLMPSEETPLQRALP 306
[61][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 66.2 bits (160), Expect = 2e-09
Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 5/90 (5%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILA-HGFKTLHLYTLNLEKSALAI 364
K +P I+ +E IKDN+EA++ +GI T +CKK+LA +H+YTLN E++ + +
Sbjct: 256 KLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEAVVKL 315
Query: 363 LKNLGLIEETSIPRTRP----ANAIQAKED 286
LK +GL E SI ++ P AN + ED
Sbjct: 316 LKRVGLWHEESIYKSLPWRPSANGKRISED 345
[62][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 66.2 bits (160), Expect = 2e-09
Identities = 32/82 (39%), Positives = 48/82 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K +IP E + ALEP+K+++ AVK G L +MC+++LA G LH YT+NL +
Sbjct: 223 RRANWTKIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
S +L+ L L P +P
Sbjct: 283 STQLVLEELNLTPSEETPLQKP 304
[63][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 65.5 bits (158), Expect = 3e-09
Identities = 35/96 (36%), Positives = 54/96 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL++
Sbjct: 114 RRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQ 173
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L L LI P +P Q+ G +E
Sbjct: 174 ATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREE 209
[64][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 65.5 bits (158), Expect = 3e-09
Identities = 35/96 (36%), Positives = 54/96 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + K +IP + + ALEP+K+++ AV+ G L MC+KILA G LH YT+NL++
Sbjct: 223 RRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L L LI P +P Q+ G +E
Sbjct: 283 ATKMVLGELELIPSHKTPLQKPLPWRQSLGLGRREE 318
[65][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 355
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 356 LKRLGMWTE 364
[66][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 373
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 374 LKRLGMWTE 382
[67][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 332
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 333 LKRLGMWTE 341
[68][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/69 (44%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C+++LA G LH YTLN E + +
Sbjct: 303 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEV 362
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 363 LKRLGMWTE 371
[69][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 65.1 bits (157), Expect = 3e-09
Identities = 33/77 (42%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH-GFKTLHLYTLNLE 382
RM C P +++ LEPIK ++ VK +GIHL +M K I G + HLYTLNLE
Sbjct: 250 RMANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRAFHLYTLNLE 309
Query: 381 KSALAILKNLGLIEETS 331
KSA ++K L + + S
Sbjct: 310 KSATCVIKVLADVPDQS 326
[70][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 64.7 bits (156), Expect = 5e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 363 LKNLGLIEE 337
LK LGL E
Sbjct: 335 LKRLGLWNE 343
[71][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 64.7 bits (156), Expect = 5e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 275 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEV 334
Query: 363 LKNLGLIEE 337
LK LGL E
Sbjct: 335 LKRLGLWNE 343
[72][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 296 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 355
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 356 LKRLGMWTE 364
[73][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 314 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 373
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 374 LKRLGMWTE 382
[74][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 64.3 bits (155), Expect = 6e-09
Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 364
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 363 LKNLGL-IEETSIP 325
L+ LGL IE+ P
Sbjct: 337 LRQLGLWIEDPRRP 350
[75][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 64.3 bits (155), Expect = 6e-09
Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAI 364
K ++P EI + +EPIKDN+ A++ YGI L +MC+ +L G LH YTLN E + + +
Sbjct: 277 KLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEV 336
Query: 363 LKNLGL-IEETSIP 325
L+ LGL IE+ P
Sbjct: 337 LRQLGLWIEDPRRP 350
[76][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 64.3 bits (155), Expect = 6e-09
Identities = 36/89 (40%), Positives = 52/89 (58%), Gaps = 4/89 (4%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K +IP EI A+EPI+DN+EA++ YG+H M +++ G LH YTLN E + + I
Sbjct: 262 KLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGLVNGLHFYTLNREVATIQI 321
Query: 363 LKNLGLIEE---TSIPRTRPANAIQAKED 286
LK +GL E P R AN + +E+
Sbjct: 322 LKQIGLWTEDIQRPWPWKRTANYNRCEEE 350
[77][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 64.3 bits (155), Expect = 6e-09
Identities = 30/77 (38%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLE 382
R +C ++P + L P+ D++E V+ G L +MC+++L G + LHLYT+NLE
Sbjct: 216 RRCSWCGVRVPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLE 275
Query: 381 KSALAILKNLGLIEETS 331
+ L IL+ LGL+ E S
Sbjct: 276 RPPLVILERLGLLPEAS 292
[78][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 64.3 bits (155), Expect = 6e-09
Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI L +C ++LA G LH YTLN E + +
Sbjct: 273 KLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEV 332
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 333 LKRLGMWTE 341
[79][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 63.9 bits (154), Expect = 8e-09
Identities = 30/69 (43%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 131 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 190
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 191 LKRLGIWNE 199
[80][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 63.9 bits (154), Expect = 8e-09
Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE
Sbjct: 223 RRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLE 282
Query: 381 KSALAILKNLGLIE 340
++ + IL+NL LIE
Sbjct: 283 RATIMILENLNLIE 296
[81][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 63.9 bits (154), Expect = 8e-09
Identities = 30/69 (43%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YG+ L MC+++L G LH YTLN E + +
Sbjct: 263 KLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEV 322
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 323 LKRLGIWNE 331
[82][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 63.9 bits (154), Expect = 8e-09
Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + ALEPIK+++ V+A G L +EMC K++ G+ LH YT+NLE
Sbjct: 223 RRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLE 282
Query: 381 KSALAILKNLGLIE 340
++ + IL+NL LIE
Sbjct: 283 RATIMILENLNLIE 296
[83][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 63.5 bits (153), Expect = 1e-08
Identities = 37/100 (37%), Positives = 56/100 (56%), Gaps = 10/100 (10%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + AL+PIKD++ V+ G L +EMC+K+L G+ LH YT+NLE
Sbjct: 223 RRAKWSEIAIPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLE 282
Query: 381 KSALAILKNLGLIEE---------TSIPRTRPANAIQAKE 289
K+ + IL+ L LIE T +P + N ++KE
Sbjct: 283 KATVMILEKLNLIEAVKSNEIVGVTELPWRKSLNPERSKE 322
[84][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/74 (43%), Positives = 47/74 (63%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 363 LKNLGL-IEETSIP 325
LK LGL IE+ P
Sbjct: 332 LKRLGLWIEDPRRP 345
[85][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 63.2 bits (152), Expect = 1e-08
Identities = 31/74 (41%), Positives = 48/74 (64%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + KIP + ALEPIKD++ V+ G L +EMC++++ G+ LH YT+NLE
Sbjct: 224 RRAKWSEIKIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLE 283
Query: 381 KSALAILKNLGLIE 340
K+ + IL+ L L+E
Sbjct: 284 KATVMILEKLNLVE 297
[86][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 63.2 bits (152), Expect = 1e-08
Identities = 32/74 (43%), Positives = 47/74 (63%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + + +
Sbjct: 272 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEV 331
Query: 363 LKNLGL-IEETSIP 325
LK LGL IE+ P
Sbjct: 332 LKRLGLWIEDPRRP 345
[87][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 62.8 bits (151), Expect = 2e-08
Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R +C+ +IP + + LEP+KD++ V+ G L +MC+K+L G K LH YT+NLE
Sbjct: 224 RRANWCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLE 283
Query: 381 KSALAILKNLGLIEETS 331
K+ + +L+ L L + S
Sbjct: 284 KATVMVLERLNLPAQDS 300
[88][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 62.8 bits (151), Expect = 2e-08
Identities = 27/66 (40%), Positives = 44/66 (66%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 355
+IP + ALEP+KD++ V+ G L EMC+K++ +G LH YT+NLEK+ I++
Sbjct: 232 RIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKATKMIIEK 291
Query: 354 LGLIEE 337
+GL+ +
Sbjct: 292 MGLLNQ 297
[89][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[90][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[91][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[92][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 62.4 bits (150), Expect = 2e-08
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 272 KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEV 331
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 332 LKQLGMWTE 340
[93][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 62.0 bits (149), Expect = 3e-08
Identities = 32/78 (41%), Positives = 44/78 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ E+++ +G + T MC+K+L G LH YTLN +
Sbjct: 240 RFSDMCGAEIPRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKAGAPGLHFYTLNQVE 299
Query: 378 SALAILKNLGLIEETSIP 325
+L I KNLGL E IP
Sbjct: 300 PSLGIWKNLGLGEREKIP 317
[94][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 62.0 bits (149), Expect = 3e-08
Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LAHGFKTLHLYTLNLE 382
RMT CK ++P I+ ALEPIK ++ AVK YG+ L M +I L + HL +LNLE
Sbjct: 286 RMTNLCKVQVPQLILDALEPIKSDDAAVKEYGVSLSIHMVGRIFLETDVRGFHLCSLNLE 345
Query: 381 KSALAILKNLG 349
KS IL+ LG
Sbjct: 346 KSIERILEGLG 356
[95][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 62.0 bits (149), Expect = 3e-08
Identities = 34/96 (35%), Positives = 50/96 (52%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R K KIP + ALEP+K+++ AV+ G L EMC+K+LA+G LH YT+NL +
Sbjct: 223 RRANHMKAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L+ L P Q+K G +E
Sbjct: 283 ATRMVLEELNWAPSAERPLQHALPWKQSKGLGRREE 318
[96][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 62.0 bits (149), Expect = 3e-08
Identities = 31/74 (41%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL--AHGFKTLHLYTLNL 385
+ T TKIP + ALEP+K ++E V+ G L +MC+KIL G + LH YT+NL
Sbjct: 184 KATNLASTKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNL 243
Query: 384 EKSALAILKNLGLI 343
EK +L+ L L+
Sbjct: 244 EKGTRMLLEELNLV 257
[97][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 278 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 337
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 338 LKQLGMWTE 346
[98][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P I +EPIKDN+ A++ YGI L +C+++L G LH YTLN E + + +
Sbjct: 313 KLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEV 372
Query: 363 LKNLGLIEE 337
LK LG+ E
Sbjct: 373 LKQLGMWTE 381
[99][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/70 (41%), Positives = 50/70 (71%), Gaps = 1/70 (1%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLEKSALAILK 358
K+P EI+ L+ K++ EA++A+GI T+MC+++ A G + +HLYTLN+EK ++IL+
Sbjct: 251 KVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLNIEKPVMSILE 310
Query: 357 NLGLIEETSI 328
NL + +E +
Sbjct: 311 NLKISKEPEL 320
[100][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 61.6 bits (148), Expect = 4e-08
Identities = 34/96 (35%), Positives = 50/96 (52%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R KIP E MA LEP+K+++ AV+ G L EMC+KI+ G + LH YT+NL +
Sbjct: 223 RRANHMNCKIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L+ L + + P R Q+ G E
Sbjct: 283 ATRMVLEELDWLPSPNRPLKRALPWKQSLGSGRRDE 318
[101][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 61.6 bits (148), Expect = 4e-08
Identities = 32/74 (43%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLE
Sbjct: 223 RRAKWSEIAIPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLE 282
Query: 381 KSALAILKNLGLIE 340
K+ + IL+ L LIE
Sbjct: 283 KATVMILEKLNLIE 296
[102][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 61.6 bits (148), Expect = 4e-08
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 354 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 253
L ++ S P A+ N +R E++
Sbjct: 297 LNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[103][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 61.6 bits (148), Expect = 4e-08
Identities = 29/74 (39%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + AL PIK+++ A++ G L +EMC+K++ G+ LH YT+NLE
Sbjct: 226 RRANWSQVAIPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLE 285
Query: 381 KSALAILKNLGLIE 340
+S + IL+ L L+E
Sbjct: 286 RSTVMILEKLNLVE 299
[104][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 61.6 bits (148), Expect = 4e-08
Identities = 33/84 (39%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + K IP + + LEP+K+++ AVK G L +MC+++LA G LH YT+NL +
Sbjct: 223 RRANWTKIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLI--EETSIPRTRP 313
+ +L L L+ EET I R P
Sbjct: 283 ATQLVLDELKLLPSEETPIQRPLP 306
[105][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 61.6 bits (148), Expect = 4e-08
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH--GFKTLHLYTLNL 385
R T K +P + ALEPIK+++E V+ G L +MC++IL G + LH YT+NL
Sbjct: 224 RATSLAKIVVPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNL 283
Query: 384 EKSALAILKNLGLI 343
EK +L+ L L+
Sbjct: 284 EKGTKMLLEELNLV 297
[106][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 61.6 bits (148), Expect = 4e-08
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 354 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 253
L ++ S P A+ N +R E++
Sbjct: 297 LNILPTESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[107][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 61.2 bits (147), Expect = 5e-08
Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P EI +EPIKDN+ A++ YGI +C+++LA G LH YTLN E + +
Sbjct: 272 KLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHFYTLNREVATTEV 331
Query: 363 LKNLGL 346
LK LG+
Sbjct: 332 LKRLGM 337
[108][TOP]
>UniRef100_A4FAF8 Methylenetetrahydrofolate reductase n=1 Tax=Saccharopolyspora
erythraea NRRL 2338 RepID=A4FAF8_SACEN
Length = 294
Score = 61.2 bits (147), Expect = 5e-08
Identities = 25/63 (39%), Positives = 41/63 (65%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNL 352
+P ++ LEP+ D+ A +A G+ L TE+C++++A G LH YTLN K+ ++ NL
Sbjct: 228 VPPAVLERLEPLADDAAAFRAEGVVLATELCERLIAEGVPALHFYTLNRSKATREVVSNL 287
Query: 351 GLI 343
GL+
Sbjct: 288 GLL 290
[109][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 61.2 bits (147), Expect = 5e-08
Identities = 31/77 (40%), Positives = 45/77 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ ++++ +G + TEMC K+LA G LH YTLN +
Sbjct: 211 RFSDMCGAEIPRWIRKQLEAYGDDSDSIRKFGEEVVTEMCAKLLAAGAPGLHFYTLNQAE 270
Query: 378 SALAILKNLGLIEETSI 328
+L+I KNLG+ E I
Sbjct: 271 PSLSIWKNLGIGEREKI 287
[110][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 61.2 bits (147), Expect = 5e-08
Identities = 31/65 (47%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAILKN 355
IP + AL+PIKD++ V+ G L +EMC K+L G+ LH YT+NLEK+ + IL+
Sbjct: 232 IPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEK 291
Query: 354 LGLIE 340
L LIE
Sbjct: 292 LNLIE 296
[111][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 61.2 bits (147), Expect = 5e-08
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 48 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 107
Query: 354 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 253
L ++ S P A+ N +R E++
Sbjct: 108 LNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 140
[112][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 61.2 bits (147), Expect = 5e-08
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLEKSALAILKN 355
IP + L+PIKD++E V+ G +L EMC+K+L G+ + LH+YT+NLEK+ L IL+
Sbjct: 237 IPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILER 296
Query: 354 LGLIEETSIPRTRPANAIQAKEDGENQERPTEDM 253
L ++ S P A+ N +R E++
Sbjct: 297 LNILPMESEFNAHPL-AVLPWRKSLNPKRKNEEV 329
[113][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 60.5 bits (145), Expect = 9e-08
Identities = 31/78 (39%), Positives = 45/78 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + +IP E + LEPIK ++ AV+ G L E+C+KILA G LH YT+NL +
Sbjct: 218 RRANHMQARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQ 277
Query: 378 SALAILKNLGLIEETSIP 325
S IL++L + + P
Sbjct: 278 STALILEDLDWLPSPNKP 295
[114][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +
Sbjct: 398 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 457
Query: 363 LKNLGL-IEETSIP 325
LK LG+ IE+ P
Sbjct: 458 LKRLGMWIEDPRRP 471
[115][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
K ++P +I +EPIKDN+ A++ YGI +C+++L G LH YTLN E + +
Sbjct: 314 KLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEV 373
Query: 363 LKNLGL-IEETSIP 325
LK LG+ IE+ P
Sbjct: 374 LKRLGMWIEDPRRP 387
[116][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 60.1 bits (144), Expect = 1e-07
Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 4/74 (5%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT----LHLYTL 391
+MT FC +P+ +M L I+ ++EAVK G + EMC++IL+ G + H YTL
Sbjct: 214 KMTQFCGISVPSAVMDRLSNIRLDDEAVKQVGCKIVAEMCEQILSAGLEVDVDGFHFYTL 273
Query: 390 NLEKSALAILKNLG 349
NLE+S IL +LG
Sbjct: 274 NLERSTTRILTSLG 287
[117][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 60.1 bits (144), Expect = 1e-07
Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG--FKTLHLYTLNL 385
RM CKT++P ++ +E +K+N EA+K YG+ +M ++I A G + LH YTLN
Sbjct: 234 RMVSLCKTRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNS 293
Query: 384 EKSALAILKNLGLIEE 337
+LK L + E
Sbjct: 294 SAQTFQVLKRLNALVE 309
[118][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 60.1 bits (144), Expect = 1e-07
Identities = 32/87 (36%), Positives = 49/87 (56%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKNL 352
IP + + ALEP+K+++ AV+ G L MC+K+LA G LH YT+NL+++ +L L
Sbjct: 218 IPPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGEL 277
Query: 351 GLIEETSIPRTRPANAIQAKEDGENQE 271
LI P +P Q+ G +E
Sbjct: 278 ELIPSHKTPLQKPLPWRQSLGLGRREE 304
[119][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R + + IP + LEPIKD++ V+ G L ++MC K+L GF LH YT+NLE
Sbjct: 223 RRAKWSQIAIPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLE 282
Query: 381 KSALAILKNLGLIE 340
++ + IL+ L +IE
Sbjct: 283 RATIMILETLNIIE 296
[120][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 59.7 bits (143), Expect = 1e-07
Identities = 30/71 (42%), Positives = 44/71 (61%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP + LE D+ ++++A+G + TEMC+K+LA G LH YTLN +
Sbjct: 211 RFSDACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAGGAPGLHFYTLNQAE 270
Query: 378 SALAILKNLGL 346
+LAI NLGL
Sbjct: 271 PSLAIWNNLGL 281
[121][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 59.7 bits (143), Expect = 1e-07
Identities = 28/69 (40%), Positives = 41/69 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C IPA + ++PI+D+ EAVKA GI L + C+++L G LH YTLN +
Sbjct: 179 RFSSMCGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGVPGLHFYTLNKSE 238
Query: 378 SALAILKNL 352
+ +AI L
Sbjct: 239 ATIAIRNQL 247
[122][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 59.3 bits (142), Expect = 2e-07
Identities = 33/96 (34%), Positives = 50/96 (52%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + KIP E + ALEP+K+++ AV+ G L MC+K+LA+G LH YT+NL +
Sbjct: 223 RRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRPANAIQAKEDGENQE 271
+ +L+ L P Q+K G +E
Sbjct: 283 ATRMLLEELQWAPSADRPLQHALPWKQSKGLGRREE 318
[123][TOP]
>UniRef100_A1U549 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter aquaeolei
VT8 RepID=A1U549_MARAV
Length = 289
Score = 59.3 bits (142), Expect = 2e-07
Identities = 29/77 (37%), Positives = 45/77 (58%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ ++++ +G + TEMC+K+L G LH YTLN +
Sbjct: 211 RFSDMCGAEIPRWIRKQLEAYGDDTDSIRKFGEEVVTEMCQKLLKAGAPGLHFYTLNQAE 270
Query: 378 SALAILKNLGLIEETSI 328
+L+I KNLG+ + I
Sbjct: 271 PSLSIWKNLGISDREKI 287
[124][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 59.3 bits (142), Expect = 2e-07
Identities = 31/72 (43%), Positives = 47/72 (65%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E
Sbjct: 259 RIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNRE 318
Query: 381 KSALAILKNLGL 346
S ILK+LGL
Sbjct: 319 GSIREILKSLGL 330
[125][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 59.3 bits (142), Expect = 2e-07
Identities = 31/72 (43%), Positives = 47/72 (65%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E
Sbjct: 280 RIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNRE 339
Query: 381 KSALAILKNLGL 346
S ILK+LGL
Sbjct: 340 GSIREILKSLGL 351
[126][TOP]
>UniRef100_C6P2D6 Methylenetetrahydrofolate reductase n=1 Tax=Sideroxydans
lithotrophicus ES-1 RepID=C6P2D6_9GAMM
Length = 280
Score = 58.9 bits (141), Expect = 2e-07
Identities = 27/70 (38%), Positives = 45/70 (64%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP + +E D+ E+V+A+G+ + T++C+K++A G +LH YTLN
Sbjct: 209 RFSDNCGAEIPRWMRKTMEGYGDDSESVQAFGLDVVTQLCEKLIAGGAPSLHFYTLNQAN 268
Query: 378 SALAILKNLG 349
++L ILK LG
Sbjct: 269 ASLEILKRLG 278
[127][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 58.5 bits (140), Expect = 3e-07
Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E
Sbjct: 281 RIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNRE 340
Query: 381 KSALAILKNLGL 346
S ILK LGL
Sbjct: 341 GSIREILKALGL 352
[128][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 58.5 bits (140), Expect = 3e-07
Identities = 28/72 (38%), Positives = 45/72 (62%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP + ALE D+EE+++A+G+ L TE+C+ +L + LH YT+N +
Sbjct: 208 RFSDTCGAEIPRWLRKALENYGDDEESLRAFGVDLVTELCEVLLENEAPGLHFYTMNQTE 267
Query: 378 SALAILKNLGLI 343
I++NLGLI
Sbjct: 268 PTAQIVRNLGLI 279
[129][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 58.5 bits (140), Expect = 3e-07
Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R+ + +IP I+ LEPIK +++AV+ YG EMC+++L +G ++HLYT+N E
Sbjct: 331 RIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNRE 390
Query: 381 KSALAILKNLGL 346
S ILK LGL
Sbjct: 391 GSIREILKALGL 402
[130][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 58.5 bits (140), Expect = 3e-07
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLN 388
R T KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLN
Sbjct: 237 RTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLN 296
Query: 387 LEKSALAILKNLGLIEE 337
LEK+ I++ GLI +
Sbjct: 297 LEKTVSFIIERCGLIPD 313
[131][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 58.5 bits (140), Expect = 3e-07
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLN 388
R T KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLN
Sbjct: 237 RTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLN 296
Query: 387 LEKSALAILKNLGLIEE 337
LEK+ I++ GLI +
Sbjct: 297 LEKTVSFIIERCGLIPD 313
[132][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 58.5 bits (140), Expect = 3e-07
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLN 388
R T KIP +IM+ LE +K +++AVK G+ + +++ KKI GF+ H YTLN
Sbjct: 264 RTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLN 323
Query: 387 LEKSALAILKNLGLIEE 337
LEK+ I++ GLI +
Sbjct: 324 LEKTVSFIIERCGLIPD 340
[133][TOP]
>UniRef100_Q0VL81 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax borkumensis
SK2 RepID=Q0VL81_ALCBS
Length = 275
Score = 58.2 bits (139), Expect = 4e-07
Identities = 28/71 (39%), Positives = 42/71 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +P + + L IKD++ AVKA+G + T +C+++LA G LH YT+N
Sbjct: 205 RFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVVTRLCERLLAMGAPGLHFYTMNQAG 264
Query: 378 SALAILKNLGL 346
L IL NLG+
Sbjct: 265 PNLRILDNLGM 275
[134][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 58.2 bits (139), Expect = 4e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R + + K +IP + + LEP+K ++ V+ G L EMC+K+LA G LH YT+NL
Sbjct: 223 RRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLA 282
Query: 381 KSALAILKNLGLIEETSIPRTRP 313
++ IL+ L L+ P +P
Sbjct: 283 QATRLILEELRLLPSEEAPLQKP 305
[135][TOP]
>UniRef100_B4X3B0 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax sp. DG881
RepID=B4X3B0_9GAMM
Length = 275
Score = 57.8 bits (138), Expect = 6e-07
Identities = 28/71 (39%), Positives = 42/71 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +P + + L IKD++ AVKA+G + T +C+++LA G LH YT+N
Sbjct: 205 RFSSTCGADVPRWLQSKLNDIKDDDVAVKAFGEEVVTRLCERLLAMGAPGLHFYTMNQAG 264
Query: 378 SALAILKNLGL 346
L IL NLG+
Sbjct: 265 PNLRILDNLGM 275
[136][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 57.8 bits (138), Expect = 6e-07
Identities = 29/72 (40%), Positives = 48/72 (66%), Gaps = 1/72 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLE 382
R+ + IP I+ +LEPIK++++AV+ +GI +C+ +L++G T +HL+TLN E
Sbjct: 278 RVAELSQLVIPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNRE 337
Query: 381 KSALAILKNLGL 346
S+ IL+ LGL
Sbjct: 338 ASSREILQQLGL 349
[137][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 57.8 bits (138), Expect = 6e-07
Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKT-LHLYTLNLE 382
R +C IP E L+PIKD+++ V+ G L +C+K+L G+ + LH+YT+NLE
Sbjct: 227 RRANWCDVHIPQEYFDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGYVSHLHIYTMNLE 286
Query: 381 KSALAILKNLGLIEETSIP 325
K+ IL + L+ P
Sbjct: 287 KAPQMILDRMELLPSHDEP 305
[138][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 57.8 bits (138), Expect = 6e-07
Identities = 27/82 (32%), Positives = 46/82 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + IP ALEP+K+++ V+ G L +MC+K++A G LH YT+NL +
Sbjct: 223 RRAQWTRCNIPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ +L+ L L+ + P +P
Sbjct: 283 ATRMVLEELDLLPDVEAPLEKP 304
[139][TOP]
>UniRef100_C7QA95 5,10-methylenetetrahydrofolate reductase n=1 Tax=Catenulispora
acidiphila DSM 44928 RepID=C7QA95_CATAD
Length = 315
Score = 57.4 bits (137), Expect = 7e-07
Identities = 27/71 (38%), Positives = 43/71 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R+TG PA++ +L ++ ++ AV+A G+ T MC+++LA G LH TLN+
Sbjct: 231 RITGLTGQAFPADLERSLMAVEGDKAAVRAVGVDWTTRMCERLLAEGVPGLHFITLNMST 290
Query: 378 SALAILKNLGL 346
+ L I +NLGL
Sbjct: 291 ATLEIYRNLGL 301
[140][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 57.4 bits (137), Expect = 7e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG-FKTLHLYTLNLE 382
R + + K +IP + + LEP+K ++ V+ G L EMC+K+LA G LH YT+NL
Sbjct: 223 RRSNWTKIRIPPDWLDKLEPVKADDAKVREIGTKLVAEMCRKLLASGQIHHLHFYTMNLA 282
Query: 381 KSALAILKNLGLIEETSIPRTRP 313
++ IL+ L L+ P +P
Sbjct: 283 QATRLILEELRLLPSEEAPLHKP 305
[141][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 57.4 bits (137), Expect = 7e-07
Identities = 29/69 (42%), Positives = 41/69 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R KIP E M LEP+K+++ AV+ G L E+C+KILA G LH YT+NL +
Sbjct: 223 RRANHMNCKIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQ 282
Query: 378 SALAILKNL 352
+ +L+ L
Sbjct: 283 ATRMVLEEL 291
[142][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 57.0 bits (136), Expect = 9e-07
Identities = 32/90 (35%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL-AHGFKTLHLYTLNLEKSALAI 364
K ++P I+ LEPIK+++EA++ YG+ L MC+++L + +H+YTLN E + +
Sbjct: 250 KLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTLNREVATTEL 309
Query: 363 LKNLGLIEETSIPRTRP----ANAIQAKED 286
L+ LGL R P AN + +ED
Sbjct: 310 LQQLGLWRPYQSHRLLPWKPSANLKRLQED 339
[143][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 57.0 bits (136), Expect = 9e-07
Identities = 26/71 (36%), Positives = 41/71 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C IP I LE D+ +A++ +G+ + TE+C+++L G LH YTLN +
Sbjct: 216 RFSDLCGADIPRWIRKRLEAFGDDRKAIRTFGLEVVTELCRRLLEQGAPGLHFYTLNRAE 275
Query: 378 SALAILKNLGL 346
+ L + K LGL
Sbjct: 276 ACLEVWKALGL 286
[144][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 57.0 bits (136), Expect = 9e-07
Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 3/79 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMC---KKILAHGFKTLHLYTLN 388
R+T KIP EI+A +E K ++E VK G+ + +E+ KKI G + H YTLN
Sbjct: 237 RVTKLSHAKIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKISTPGHRGFHFYTLN 296
Query: 387 LEKSALAILKNLGLIEETS 331
LEKS IL+ LI +S
Sbjct: 297 LEKSVSFILERCNLIPPSS 315
[145][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/71 (36%), Positives = 42/71 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C T+IP I LE D+ E+++A+G+ + TE+C+++L G LH YT+N +
Sbjct: 50 RFSDACGTEIPRWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEGGAPGLHFYTMNQSE 109
Query: 378 SALAILKNLGL 346
L + LGL
Sbjct: 110 PTLRLCDRLGL 120
[146][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 56.6 bits (135), Expect = 1e-06
Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Frame = -1
Query: 531 IPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH---GFKTLHLYTLNLEKSALAIL 361
+P+ AL P++ ++E V+ G L +MCK IL + G K LH+YTLNLEK A +L
Sbjct: 236 VPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLL 295
Query: 360 KNLG 349
+ LG
Sbjct: 296 RELG 299
[147][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 56.6 bits (135), Expect = 1e-06
Identities = 28/78 (35%), Positives = 44/78 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R K+P E MA LE +K+++ AV+ G L +MC+KIL+ G + LH YT+NL +
Sbjct: 223 RRANHMNCKVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAGIRHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIP 325
+ +L+ L + P
Sbjct: 283 ATRMVLEELDWLPSPDRP 300
[148][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 56.6 bits (135), Expect = 1e-06
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKILAHGFKTLHLYTLN 388
R T K+P +IMA +E +K ++EAVK GI + E+ KK+ G + LH YTLN
Sbjct: 237 RTTKLSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKKLPCPGPRGLHFYTLN 296
Query: 387 LEKSALAILKNLGLIEETSIP 325
LEK+ I++ LI +S P
Sbjct: 297 LEKAVAFIVERCSLIPASSEP 317
[149][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 56.2 bits (134), Expect = 2e-06
Identities = 27/71 (38%), Positives = 43/71 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP + LE D+ ++++A+G + TEMC+++L G LH Y++NL
Sbjct: 209 RFSDACGAEIPRWVRKQLEAYGDDADSIRAFGEQVITEMCERLLQGGAPGLHFYSMNLAG 268
Query: 378 SALAILKNLGL 346
+LAI NLGL
Sbjct: 269 PSLAIWNNLGL 279
[150][TOP]
>UniRef100_B5HCL5 Methylenetetrahydrofolate reductase n=1 Tax=Streptomyces
pristinaespiralis ATCC 25486 RepID=B5HCL5_STRPR
Length = 305
Score = 56.2 bits (134), Expect = 2e-06
Identities = 28/75 (37%), Positives = 40/75 (53%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R PAE+ + +KD+ AV++ GI TE C ++LA G LH TLN
Sbjct: 231 RFATLSNAHFPAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNST 290
Query: 378 SALAILKNLGLIEET 334
+ L I +NLGL E++
Sbjct: 291 ATLEIYENLGLHEQS 305
[151][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 56.2 bits (134), Expect = 2e-06
Identities = 30/73 (41%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAH--GFKTLHLYTLNL 385
R T T +P AL+P++D+++ V+ G L EMCKKI+ G LH+YT+NL
Sbjct: 240 RATARFGTLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNL 299
Query: 384 EKSALAILKNLGL 346
EK + +L LGL
Sbjct: 300 EKGSRMLLDYLGL 312
[152][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 56.2 bits (134), Expect = 2e-06
Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 6/78 (7%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIL------AHGFKTLHLY 397
RMT C +P+ +M L K ++EA+K G+ +M KKI+ HGF H
Sbjct: 233 RMTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGF---HFC 289
Query: 396 TLNLEKSALAILKNLGLI 343
TLNLE+S ILKN GL+
Sbjct: 290 TLNLERSVALILKNSGLL 307
[153][TOP]
>UniRef100_UPI0001744B6A 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B6A
Length = 314
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/62 (41%), Positives = 37/62 (59%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 355
++PA ++ AL ++ + AV G+H TE C ++L HG +HLYTLN L ILK
Sbjct: 235 RVPARLLKALMKVQHDPAAVLEVGLHHATEQCSELLHHGVSGIHLYTLNQAGPILEILKR 294
Query: 354 LG 349
LG
Sbjct: 295 LG 296
[154][TOP]
>UniRef100_C1DIB8 Methylenetetrahydrofolate reductase n=1 Tax=Azotobacter vinelandii
DJ RepID=C1DIB8_AZOVD
Length = 281
Score = 55.8 bits (133), Expect = 2e-06
Identities = 28/71 (39%), Positives = 42/71 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C ++P + LE D+ E+++A+G + T MC+K+L G LH YTLN +
Sbjct: 209 RFSDACGAELPRWVRKQLEAYGDDLESIQAFGEQVVTAMCEKLLEGGAPGLHFYTLNQAE 268
Query: 378 SALAILKNLGL 346
+LAI NLGL
Sbjct: 269 PSLAIWNNLGL 279
[155][TOP]
>UniRef100_B6J3R7 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
CbuG_Q212 RepID=B6J3R7_COXB2
Length = 290
Score = 55.8 bits (133), Expect = 2e-06
Identities = 25/69 (36%), Positives = 44/69 (63%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN +
Sbjct: 209 RFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCE 268
Query: 378 SALAILKNL 352
I++NL
Sbjct: 269 PTQTIIENL 277
[156][TOP]
>UniRef100_A9N9C8 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=A9N9C8_COXBR
Length = 290
Score = 55.8 bits (133), Expect = 2e-06
Identities = 25/69 (36%), Positives = 44/69 (63%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN +
Sbjct: 209 RFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCE 268
Query: 378 SALAILKNL 352
I++NL
Sbjct: 269 PTQTIIENL 277
[157][TOP]
>UniRef100_C9YE70 5,10-methylenetetrahydrofolate reductase n=1 Tax=Curvibacter
putative symbiont of Hydra magnipapillata
RepID=C9YE70_9BURK
Length = 305
Score = 55.8 bits (133), Expect = 2e-06
Identities = 26/71 (36%), Positives = 41/71 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I L+ D ++KA+G+ + T++C+++ A G LH YT+N
Sbjct: 233 RFSDACGAEIPRWIRLRLQSYGDEVASIKAFGLEVVTDLCEQLRAGGAPALHFYTMNQSA 292
Query: 378 SALAILKNLGL 346
LA+ KNLGL
Sbjct: 293 PTLALCKNLGL 303
[158][TOP]
>UniRef100_B6J6H7 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=B6J6H7_COXB1
Length = 290
Score = 55.8 bits (133), Expect = 2e-06
Identities = 25/69 (36%), Positives = 44/69 (63%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN +
Sbjct: 209 RFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCE 268
Query: 378 SALAILKNL 352
I++NL
Sbjct: 269 PTQTIIENL 277
[159][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 55.8 bits (133), Expect = 2e-06
Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R +C+ +P+ L+ KD++ V+ G L +MC K++ G+ LH YT+NLE
Sbjct: 209 RRAKWCQINVPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLE 268
Query: 381 KSALAILKNLGLIEETSIP 325
KS + +L+ L LI+ + P
Sbjct: 269 KSTIMVLEKLQLIDTHNQP 287
[160][TOP]
>UniRef100_Q8Y389 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=Q8Y389_RALSO
Length = 276
Score = 55.5 bits (132), Expect = 3e-06
Identities = 27/71 (38%), Positives = 41/71 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN
Sbjct: 206 RFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAA 265
Query: 378 SALAILKNLGL 346
+ AI + LGL
Sbjct: 266 ATRAIWQRLGL 276
[161][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 55.5 bits (132), Expect = 3e-06
Identities = 25/71 (35%), Positives = 43/71 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D++++++A+GI + T++C+ +L G +H YT+N +
Sbjct: 208 RFSKNCGAEIPRWISKRLEGFADDQDSIRAFGIDVVTQLCQTLLESGAPGIHFYTMNQTQ 267
Query: 378 SALAILKNLGL 346
L I +NLGL
Sbjct: 268 PTLQICRNLGL 278
[162][TOP]
>UniRef100_B5S7H8 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=B5S7H8_RALSO
Length = 276
Score = 55.5 bits (132), Expect = 3e-06
Identities = 27/71 (38%), Positives = 41/71 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN
Sbjct: 206 RFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAA 265
Query: 378 SALAILKNLGL 346
+ AI + LGL
Sbjct: 266 ATRAIWQRLGL 276
[163][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 55.5 bits (132), Expect = 3e-06
Identities = 36/98 (36%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Frame = -1
Query: 540 KTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLEKSALAI 364
+ ++P IM L+ IKDN+ A++ YG+ MC+++L G LH YTLN E + I
Sbjct: 216 RLEVPKSIMDDLQTIKDNDVAIRNYGVQKAINMCRELLDSGLVPGLHFYTLNREVATREI 275
Query: 363 LKNLGL-IEETSIPRTRPANAIQAKEDGENQERPTEDM 253
L LGL + + R P A NQ+R TED+
Sbjct: 276 LTALGLWCMDPAASRPLPWRA------SANQKRFTEDV 307
[164][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 55.5 bits (132), Expect = 3e-06
Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGF-KTLHLYTLNLE 382
R+ K +P I + L+PI ++ VK YG L T+M +I+ G +HL TLNLE
Sbjct: 226 RLVNLTKCPVPDSITSDLQPISSDDATVKRYGAELATKMVSQIIESGLVPGVHLCTLNLE 285
Query: 381 KSALAILKNLG 349
KS IL NLG
Sbjct: 286 KSVRMILDNLG 296
[165][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 55.5 bits (132), Expect = 3e-06
Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKI-LAHGFKTLHLYTLNLE 382
R+T C T++PA I L PI +++ VK YG+ L +M +++ L G + H TLNLE
Sbjct: 225 RLTKLCGTRVPACITEDLAPISHDDQLVKDYGVKLAVQMIRRLRLEGGIQGFHFCTLNLE 284
Query: 381 KSALAILKNLGLIEETSIPRTRPA 310
KS +L+ L +T PA
Sbjct: 285 KSVQRVLETLRWAGDTPGTMEPPA 308
[166][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 55.5 bits (132), Expect = 3e-06
Identities = 27/70 (38%), Positives = 42/70 (60%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 355
KIP + A+LE +K+++ AV+ G L EMC++I+ G LH YT+NL ++ +L+
Sbjct: 231 KIPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEE 290
Query: 354 LGLIEETSIP 325
L L T P
Sbjct: 291 LNLTPSTQRP 300
[167][TOP]
>UniRef100_Q2L158 Methylenetetrahydrofolate reductase n=1 Tax=Bordetella avium 197N
RepID=Q2L158_BORA1
Length = 280
Score = 55.1 bits (131), Expect = 4e-06
Identities = 24/69 (34%), Positives = 42/69 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C ++P I L D++ +++A+G+ + T++C+ +L HG LH YTLN +
Sbjct: 210 RFSEMCGAELPRWIRLRLAEFGDDKASIRAFGVDVVTKLCQTLLDHGVPGLHFYTLNQSE 269
Query: 378 SALAILKNL 352
+ L+I KNL
Sbjct: 270 ATLSIWKNL 278
[168][TOP]
>UniRef100_A9KD99 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
Dugway 5J108-111 RepID=A9KD99_COXBN
Length = 290
Score = 55.1 bits (131), Expect = 4e-06
Identities = 24/64 (37%), Positives = 42/64 (65%)
Frame = -1
Query: 543 CKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAI 364
C T+IP + LE K+++ ++KAYG+ + T++C+ ++A+G LH YTLN + I
Sbjct: 214 CATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTI 273
Query: 363 LKNL 352
++NL
Sbjct: 274 IENL 277
[169][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 55.1 bits (131), Expect = 4e-06
Identities = 27/71 (38%), Positives = 41/71 (57%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D+ E+++A+G+ + T +C ++LA G LH YTLN
Sbjct: 206 RFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGGAPGLHFYTLNAAG 265
Query: 378 SALAILKNLGL 346
+ AI + LGL
Sbjct: 266 ATRAIWQRLGL 276
[170][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C ++P I LE D+ E+++A+G+ + T MC ++L G LH YTLN
Sbjct: 206 RFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGGAPGLHFYTLNAAG 265
Query: 378 SALAILKNLGL 346
S AI + LGL
Sbjct: 266 STRAIWQRLGL 276
[171][TOP]
>UniRef100_C5BTQ6 Methylenetetrahydrofolate reductase n=1 Tax=Teredinibacter turnerae
T7901 RepID=C5BTQ6_TERTT
Length = 282
Score = 54.7 bits (130), Expect = 5e-06
Identities = 27/73 (36%), Positives = 41/73 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I L DN+E+++A+ L TE+C +L +G LH YT+N +
Sbjct: 210 RFSDACGAEIPRWIRKRLNDFGDNQESLQAFTTDLVTELCATLLENGAPGLHFYTMNQVE 269
Query: 378 SALAILKNLGLIE 340
IL NLGL++
Sbjct: 270 PTRTILTNLGLVD 282
[172][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 54.7 bits (130), Expect = 5e-06
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C ++P I LE D+ E+++A+G+ + T MC ++L G LH YTLN
Sbjct: 206 RFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGGAPGLHFYTLNAAG 265
Query: 378 SALAILKNLGL 346
S AI + LGL
Sbjct: 266 STRAIWQRLGL 276
[173][TOP]
>UniRef100_Q84CU6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=uncultured
bacterium RepID=Q84CU6_9BACT
Length = 253
Score = 54.7 bits (130), Expect = 5e-06
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R +G C +IP + LE D+ +++A GI + +E+C+ +LA G +LH YTLN
Sbjct: 174 RFSGVCGAEIPRWLRLRLEAYADDMPSLRALGIDVVSELCEVLLAGGVPSLHFYTLNQAG 233
Query: 378 SALAILKNLGLIEETSIPR 322
I+ N+GL + T+ R
Sbjct: 234 IISTIINNVGLEDATTQKR 252
[174][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 54.7 bits (130), Expect = 5e-06
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG--FKTLHLYTLNL 385
RM CKT +P+++ +E +K+N + +K YG+ +M + I A G + LH YTLN
Sbjct: 234 RMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRASGLDYHHLHFYTLNN 293
Query: 384 EKSALAILKNLGLIEE 337
ILK L + E
Sbjct: 294 SAQIFKILKRLNALVE 309
[175][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 54.7 bits (130), Expect = 5e-06
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKILAHGFKTLHLYTLN 388
R T K+P +IMA +E +K ++EAVK GI + E+ K + G + LH YTLN
Sbjct: 237 RTTKLSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLHFYTLN 296
Query: 387 LEKSALAILKNLGLIEETSIP 325
LEK+ I++ LI +S P
Sbjct: 297 LEKAVAFIVERCNLIPTSSEP 317
[176][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 54.7 bits (130), Expect = 5e-06
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEM---CKKILAHGFKTLHLYTLN 388
R T K+P +IMA +E +K ++EAVK GI + E+ K + G + LH YTLN
Sbjct: 237 RTTKLSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLHFYTLN 296
Query: 387 LEKSALAILKNLGLIEETSIP 325
LEK+ I++ LI +S P
Sbjct: 297 LEKAVAFIVERCNLIPTSSEP 317
[177][TOP]
>UniRef100_Q6J6A1 Methylenetetrahydrofolate reductase n=1 Tax=Collimonas fungivorans
RepID=Q6J6A1_9BURK
Length = 284
Score = 54.3 bits (129), Expect = 6e-06
Identities = 25/71 (35%), Positives = 43/71 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C T+IP I L D+ ++++A+G+ + T++C+++LA G LH YTLN
Sbjct: 214 RFSDMCGTEIPRWIRLKLASYGDDSDSIRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSP 273
Query: 378 SALAILKNLGL 346
+ +AI + L L
Sbjct: 274 ATIAIWQRLKL 284
[178][TOP]
>UniRef100_A3TKC9 Methylenetetrahydrofolate reductase n=1 Tax=Janibacter sp. HTCC2649
RepID=A3TKC9_9MICO
Length = 295
Score = 54.3 bits (129), Expect = 6e-06
Identities = 24/71 (33%), Positives = 43/71 (60%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
RMT T +PA ++ L+ + ++ AV++ G+ + TE+ +++LA G LH T+N
Sbjct: 220 RMTELMGTPLPAAVVDRLQAVSEDPAAVRSVGVEIATEIAQRMLAEGAPGLHFITMNRST 279
Query: 378 SALAILKNLGL 346
+ L + +NLGL
Sbjct: 280 ATLEVYENLGL 290
[179][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 54.3 bits (129), Expect = 6e-06
Identities = 26/82 (31%), Positives = 45/82 (54%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + + IP ALEPIK+++ V+ G L +MC++++ G LH YT+NL +
Sbjct: 223 RRAQWTRCNIPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEAGITHLHFYTMNLAQ 282
Query: 378 SALAILKNLGLIEETSIPRTRP 313
+ +L+ L L+ + P +P
Sbjct: 283 ATRMVLEELDLLPDPGSPLEKP 304
[180][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 54.3 bits (129), Expect = 6e-06
Identities = 27/70 (38%), Positives = 41/70 (58%)
Frame = -1
Query: 534 KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILKN 355
KIP + AALE +K+++ AV+ G L EMC++I+ G LH YT+NL ++ +L+
Sbjct: 231 KIPPKWSAALEEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEE 290
Query: 354 LGLIEETSIP 325
L L P
Sbjct: 291 LSLTPSNQRP 300
[181][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 53.9 bits (128), Expect = 8e-06
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
+ C IP E++ E DN E K GI T C ++ HG K LH YTLN
Sbjct: 219 KFASLCGATIPEEVVQKFEKYADNPEETKKIGIEFATLQCMDLIKHGVKGLHFYTLNKSD 278
Query: 378 SALAILKNL 352
+ + I +N+
Sbjct: 279 ATIKIYENI 287
[182][TOP]
>UniRef100_C4BW20 Methylenetetrahydrofolate reductase n=1 Tax=Sebaldella termitidis
ATCC 33386 RepID=C4BW20_9FUSO
Length = 292
Score = 53.9 bits (128), Expect = 8e-06
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R+T C KIP ++ L +DN EA+ GI TE ++L+ G K +H+YT+N
Sbjct: 216 RITSLCNCKIPKKLERILNAYEDNNEAMYQAGIAYATEQIIELLSAGIKGIHIYTMNKTN 275
Query: 378 SALAILKNLGLIEE 337
+ IL+N+ I +
Sbjct: 276 AVKEILENISSIRK 289
[183][TOP]
>UniRef100_A4A9E4 Methylenetetrahydrofolate reductase n=1 Tax=Congregibacter
litoralis KT71 RepID=A4A9E4_9GAMM
Length = 278
Score = 53.9 bits (128), Expect = 8e-06
Identities = 25/71 (35%), Positives = 42/71 (59%)
Frame = -1
Query: 558 RMTGFCKTKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEK 379
R + C +IP I LE D++E+++A+GI + T++C+ +L +H YT+N +
Sbjct: 208 RFSKNCGAEIPRWISKRLEGFADDQESIRAFGIDVVTQLCQTLLESDAPGIHFYTMNQAQ 267
Query: 378 SALAILKNLGL 346
L I +NLGL
Sbjct: 268 PTLQICRNLGL 278