[UP]
[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 206 bits (524), Expect = 7e-52
Identities = 100/118 (84%), Positives = 108/118 (91%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+IEKIH AA++DPN+VVFSFEFFPPKTEDGV NL ERMDRMV H+PSFCDITW AGG+
Sbjct: 1 MKIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGT 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA KMQN V VETMMHLTCTNMPVEKID AL TIKSNGLQNVLALRGDPPH
Sbjct: 60 TADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPH 117
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 204 bits (518), Expect = 3e-51
Identities = 103/130 (79%), Positives = 108/130 (83%), Gaps = 12/130 (9%)
Frame = +1
Query: 82 MKVIEKIHEAAA------------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP 225
MKVI+KI EAA S NKVVFSFEFFPPKTEDGV NL ERMDRMVAH+P
Sbjct: 1 MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP 60
Query: 226 SFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQN 405
SFCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QN
Sbjct: 61 SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 406 VLALRGDPPH 435
VLALRGDPPH
Sbjct: 121 VLALRGDPPH 130
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 201 bits (512), Expect = 2e-50
Identities = 101/127 (79%), Positives = 108/127 (85%), Gaps = 9/127 (7%)
Frame = +1
Query: 82 MKVIEKIHEAAA---------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFC 234
MKVI+KI AAA S NKVVFSFEFFPPKT+DGV NL ERMDRMV+H+PSFC
Sbjct: 1 MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC 60
Query: 235 DITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLA 414
DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QNVLA
Sbjct: 61 DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA 120
Query: 415 LRGDPPH 435
LRGDPPH
Sbjct: 121 LRGDPPH 127
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 200 bits (508), Expect = 5e-50
Identities = 97/118 (82%), Positives = 106/118 (89%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPH
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPH 117
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 200 bits (508), Expect = 5e-50
Identities = 97/118 (82%), Positives = 106/118 (89%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPH
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPH 117
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 200 bits (508), Expect = 5e-50
Identities = 97/118 (82%), Positives = 106/118 (89%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPH
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPH 117
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 197 bits (500), Expect = 4e-49
Identities = 96/118 (81%), Positives = 105/118 (88%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPH 116
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 197 bits (500), Expect = 4e-49
Identities = 96/118 (81%), Positives = 105/118 (88%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPH 116
[9][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 196 bits (499), Expect = 5e-49
Identities = 96/118 (81%), Positives = 104/118 (88%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI EAA + + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPH 116
[10][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 195 bits (495), Expect = 2e-48
Identities = 96/118 (81%), Positives = 103/118 (87%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI EAA + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPH 116
[11][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 192 bits (489), Expect = 7e-48
Identities = 98/131 (74%), Positives = 108/131 (82%), Gaps = 13/131 (9%)
Frame = +1
Query: 82 MKVIEKIHEA------------AASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS 222
MKVI+KI + A SD N KVVFSFEFFPPKTEDGV NL +RMDRMV+H+
Sbjct: 1 MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN 60
Query: 223 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 402
P+FCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+Q
Sbjct: 61 PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ 120
Query: 403 NVLALRGDPPH 435
NVLALRGDPPH
Sbjct: 121 NVLALRGDPPH 131
[12][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 192 bits (488), Expect = 1e-47
Identities = 94/118 (79%), Positives = 102/118 (86%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVI+KI A D K FSFEFFPPKTEDGV NL ERMDRMVA+ P+FCDITWGAGGS
Sbjct: 1 MKVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TLDIA +MQN V VE+MMHLTCTNMPVEKID ALETI+SNG+QNVLALRGDPPH
Sbjct: 59 TADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPH 116
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 190 bits (483), Expect = 4e-47
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVIEKI A KVVFSFEFFPPKTE+GV NL +RMDRMV H PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TLDI+ KMQN + VE+MMHLTCTNMPVEKID AL TIK+NG+QNVLALRGDPPH
Sbjct: 59 TADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPH 116
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 185 bits (470), Expect = 1e-45
Identities = 86/118 (72%), Positives = 103/118 (87%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPH 116
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 185 bits (470), Expect = 1e-45
Identities = 86/118 (72%), Positives = 103/118 (87%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPH 116
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 185 bits (470), Expect = 1e-45
Identities = 86/118 (72%), Positives = 103/118 (87%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPH
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPH 116
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 179 bits (455), Expect = 7e-44
Identities = 86/118 (72%), Positives = 99/118 (83%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
T+ VTLDIA KMQN + VETMMHLTCTNM VE +D AL+++KSNG+QN+LALRGDPPH
Sbjct: 59 TSAVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPH 116
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 179 bits (455), Expect = 7e-44
Identities = 85/118 (72%), Positives = 99/118 (83%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
T+ +TLDIA KMQN + VETMMHLTCTNM VE +D+AL+ +KSNG+QN+LALRGDPPH
Sbjct: 59 TSAITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPH 116
[19][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 166 bits (421), Expect = 6e-40
Identities = 79/117 (67%), Positives = 93/117 (79%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I K+ E + FSFEFFPP+TE+GV NL ER+DRMVA+ P FCDITWGAGGS
Sbjct: 1 MKLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TADVTLDIA +MQN + VETMMHLTCTNMP EK++ AL +K G+QN+LALRGDPP
Sbjct: 59 TADVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPP 115
[20][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 164 bits (416), Expect = 2e-39
Identities = 77/92 (83%), Positives = 84/92 (91%)
Frame = +1
Query: 160 PKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTC 339
P+ +GV NL ERMDRMVAH P+FCDITWGAGGSTADVTLDIA +MQN V VETMMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 340 TNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
TNMPVEKID+AL+TIKSNG+QNVLALRGDPPH
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNVLALRGDPPH 104
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 144 bits (362), Expect = 4e-33
Identities = 70/117 (59%), Positives = 89/117 (76%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P F DITWGAGGS
Sbjct: 4 MKIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGS 61
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ +TL+IA+K QN G+ETMMHLTCTNMPV +I AL+ KS G++N+LALRGDPP
Sbjct: 62 TSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNILALRGDPP 118
[22][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 137 bits (346), Expect = 3e-31
Identities = 65/117 (55%), Positives = 87/117 (74%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ +KI ++A +D K+ +SFE+FPP+T G+ NLL+R++RM A P F DITW AGG
Sbjct: 1 MKITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL K +G +NVLALRGDPP
Sbjct: 59 TSDLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPP 115
[23][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 131 bits (330), Expect = 2e-29
Identities = 64/119 (53%), Positives = 83/119 (69%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEA--AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAG 255
MK+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P F DITW AG
Sbjct: 1 MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG 60
Query: 256 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G ++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNILALRGDPP 119
[24][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 131 bits (329), Expect = 3e-29
Identities = 66/118 (55%), Positives = 83/118 (70%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
MK+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPP 118
[25][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 131 bits (329), Expect = 3e-29
Identities = 66/118 (55%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
MK+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPP 118
[26][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 130 bits (328), Expect = 3e-29
Identities = 64/117 (54%), Positives = 82/117 (70%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + EK+ + A++ +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ +G N+LALRGDPP
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPP 115
[27][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 129 bits (325), Expect = 8e-29
Identities = 67/120 (55%), Positives = 84/120 (70%), Gaps = 3/120 (2%)
Frame = +1
Query: 82 MKVIEKI---HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 252
MK+ EK+ H+AA S P FSFEFF PKT GV NL +RMDRM +P F DITW A
Sbjct: 1 MKISEKLDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNA 58
Query: 253 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
GG ++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL+ +G QN+LALRGDPP
Sbjct: 59 GGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPP 118
[28][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 129 bits (325), Expect = 8e-29
Identities = 62/117 (52%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ EK+ A + FSFEFF PKT GV NL +RMDRM SP F DITW AGG
Sbjct: 1 MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR 60
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++++T ++ Q +G+ET MHLTCTNM +E ID+AL++ +G QN+LALRGDPP
Sbjct: 61 SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPP 117
[29][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 129 bits (323), Expect = 1e-28
Identities = 64/118 (54%), Positives = 83/118 (70%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
MK+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNILALRGDPP 118
[30][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 128 bits (322), Expect = 2e-28
Identities = 64/117 (54%), Positives = 78/117 (66%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + EK+ + A K SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIREKLAKNEAE--GKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MPVEK+D AL+ G N+LALRGDPP
Sbjct: 59 LSDLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPP 115
[31][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 128 bits (322), Expect = 2e-28
Identities = 63/118 (53%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPP 118
[32][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 128 bits (322), Expect = 2e-28
Identities = 64/117 (54%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M V +K+++ A +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHVKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL G N+LALRGDPP
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPP 115
[33][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 127 bits (320), Expect = 3e-28
Identities = 63/118 (53%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPP 118
[34][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 127 bits (320), Expect = 3e-28
Identities = 63/117 (53%), Positives = 81/117 (69%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL++ G N+LALRGDPP
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPP 115
[35][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 126 bits (317), Expect = 7e-28
Identities = 60/116 (51%), Positives = 79/116 (68%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 264
K+ KI A A ++ +SFE+FPP+T G+ NL +R++RM P F DITW AGG T
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T + K + +G+ET MHLTCTNMP EKID AL+ K G +N+LALRGDPP
Sbjct: 76 SDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPP 131
[36][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 126 bits (317), Expect = 7e-28
Identities = 63/117 (53%), Positives = 79/117 (67%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPP 115
[37][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 126 bits (316), Expect = 9e-28
Identities = 61/119 (51%), Positives = 82/119 (68%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ +K+ + P+K FSFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG 60
Query: 259 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ ++ Q+ +G+ET MHLTCTNMP+ +ID+ALE ++G QN+LALRGDPP
Sbjct: 61 GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPP 119
[38][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 126 bits (316), Expect = 9e-28
Identities = 62/117 (52%), Positives = 79/117 (67%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + EK+ + A+ K+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP E++D AL+ G N+LALRGDPP
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPP 115
[39][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 126 bits (316), Expect = 9e-28
Identities = 59/107 (55%), Positives = 80/107 (74%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 291
AA P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 292 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
QN +G+ T++HLTCTN E ID+AL+ K +G++N+LALRGDPP
Sbjct: 69 TCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNILALRGDPP 115
[40][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 125 bits (315), Expect = 1e-27
Identities = 59/103 (57%), Positives = 77/103 (74%)
Frame = +1
Query: 124 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 303
P++ SFEFFPPKT+ G NLL R++RM A +P F ITWGAGGST++ +LD+A Q
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTSEKSLDLAATCQK 72
Query: 304 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
VG+ T++HLTCTN E ID+AL K+NG++N+LALRGDPP
Sbjct: 73 EVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPP 115
[41][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 125 bits (315), Expect = 1e-27
Identities = 64/118 (54%), Positives = 80/118 (67%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M + +K+ H AA P+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDKLAHSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGG 57
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 58 RLSDLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNILALRGDPP 115
[42][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 125 bits (314), Expect = 1e-27
Identities = 61/117 (52%), Positives = 77/117 (65%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M++ +K+ + A + FSFEFF PKT GV NL ERMDRM P F DITW AGG
Sbjct: 1 MRISQKL-QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGR 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ D+ Q +G+ET MHLTCTNMPV +IDDAL+ G +N+LALRGDPP
Sbjct: 60 LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPP 116
[43][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 125 bits (314), Expect = 1e-27
Identities = 62/121 (51%), Positives = 80/121 (66%), Gaps = 4/121 (3%)
Frame = +1
Query: 82 MKVIEKIHEA----AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWG 249
MK+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P F DITW
Sbjct: 1 MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN 60
Query: 250 AGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
AGG ++ +T ++ Q+T+G+ET MHLTCTNMPV ID+ALE +G QN+LALRGDP
Sbjct: 61 AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP 120
Query: 430 P 432
P
Sbjct: 121 P 121
[44][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 125 bits (313), Expect = 2e-27
Identities = 59/116 (50%), Positives = 80/116 (68%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 264
K+ +++ E +A V SFEFFPP+T+DGV +L+ R+ R P F D+TWGAGGST
Sbjct: 5 KISDRLQELSAKGEKFV--SFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+TLD+ +M G MHLTCTNMP EKID AL+ + G++N++ALRGDPP
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPP 118
[45][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 125 bits (313), Expect = 2e-27
Identities = 58/107 (54%), Positives = 78/107 (72%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 291
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 292 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNILALRGDPP 115
[46][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 125 bits (313), Expect = 2e-27
Identities = 61/117 (52%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPP 115
[47][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 125 bits (313), Expect = 2e-27
Identities = 61/117 (52%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPP 115
[48][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 125 bits (313), Expect = 2e-27
Identities = 63/119 (52%), Positives = 82/119 (68%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
M++ EK+ S K FSFE+F PKT GV NL +RMDRM + P F D+TW AGG
Sbjct: 1 MRISEKLQNHR-SKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGG 59
Query: 259 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ +T D+ + Q+ +G+ET MHLTCTNMPV +IDDALE+ + +G QN+LALRGDPP
Sbjct: 60 GVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPP 118
[49][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 125 bits (313), Expect = 2e-27
Identities = 58/107 (54%), Positives = 78/107 (72%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 291
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 292 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPP 115
[50][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 125 bits (313), Expect = 2e-27
Identities = 58/107 (54%), Positives = 78/107 (72%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 291
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 292 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPP 115
[51][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 125 bits (313), Expect = 2e-27
Identities = 56/103 (54%), Positives = 77/103 (74%)
Frame = +1
Query: 124 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 303
P++ SFEFF PKT+ G NLL R++R++A +P F +TWGAGGST++ +LD+A QN
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTSEKSLDLAATCQN 72
Query: 304 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+G+ T++HLTCTN E ID AL K+NG++N+LALRGDPP
Sbjct: 73 KIGINTVLHLTCTNTDKEIIDSALARAKANGIRNILALRGDPP 115
[52][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 124 bits (312), Expect = 2e-27
Identities = 64/118 (54%), Positives = 79/118 (66%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPP 115
[53][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 124 bits (312), Expect = 2e-27
Identities = 64/118 (54%), Positives = 79/118 (66%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPP 115
[54][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 124 bits (312), Expect = 2e-27
Identities = 61/118 (51%), Positives = 79/118 (66%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 258
M+V EK+ + A+ +K FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG 60
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ ++ Q+ +G+ET MHLTCTNMP + IDDAL+ +G QN+LALRGD P
Sbjct: 61 RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAP 118
[55][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 124 bits (311), Expect = 3e-27
Identities = 60/116 (51%), Positives = 79/116 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ EK+ +A + +SFEFFPP+T G+ NL +R++RM P F DITWGAGG
Sbjct: 1 MKITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGK 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
AD+T + + Q T+G+ET MHL CT MP EK++ AL KS+G QN+LALRGDP
Sbjct: 59 NADLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDP 114
[56][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 124 bits (311), Expect = 3e-27
Identities = 60/108 (55%), Positives = 74/108 (68%)
Frame = +1
Query: 109 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 288
A A + SFEFFPPKT GV NL +RMDRM PSF DITWGAGG A++T ++
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 289 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q+ G+ET MHLTCT+MP EK+D+AL++ G N+LALRGDPP
Sbjct: 68 HVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPP 115
[57][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 124 bits (311), Expect = 3e-27
Identities = 61/117 (52%), Positives = 81/117 (69%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M V +K+ E AA+ + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHVGQKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ + Q G+ET MHLTCT+MP E++D ALE + G N+LALRGDPP
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPP 115
[58][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 124 bits (310), Expect = 4e-27
Identities = 60/117 (51%), Positives = 82/117 (70%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M V++KI+ D SFEFFPPKT+ G NLL R+ RM+A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMLALNPLFITVTWGAGGS 57
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPP 114
[59][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 124 bits (310), Expect = 4e-27
Identities = 58/106 (54%), Positives = 78/106 (73%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A P++ SFEFFPPKT+ G NLL R++RM+A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPP 115
[60][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 124 bits (310), Expect = 4e-27
Identities = 57/97 (58%), Positives = 71/97 (73%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPP 115
[61][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 124 bits (310), Expect = 4e-27
Identities = 57/97 (58%), Positives = 71/97 (73%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPP 115
[62][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 124 bits (310), Expect = 4e-27
Identities = 60/117 (51%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPP 115
[63][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 124 bits (310), Expect = 4e-27
Identities = 60/117 (51%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPP 115
[64][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 123 bits (309), Expect = 6e-27
Identities = 58/101 (57%), Positives = 72/101 (71%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPP 115
[65][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 123 bits (309), Expect = 6e-27
Identities = 57/97 (58%), Positives = 71/97 (73%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 79 CMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPP 115
[66][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 123 bits (309), Expect = 6e-27
Identities = 58/101 (57%), Positives = 72/101 (71%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPP 115
[67][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 123 bits (309), Expect = 6e-27
Identities = 58/101 (57%), Positives = 72/101 (71%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPP 115
[68][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 123 bits (308), Expect = 7e-27
Identities = 58/106 (54%), Positives = 70/106 (66%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A + K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG + +T ++ K
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKLTCEMVKV 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q G+ET MHLTCT+M K+DDAL +G N+LALRGDPP
Sbjct: 70 AQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPP 115
[69][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 122 bits (307), Expect = 9e-27
Identities = 58/106 (54%), Positives = 77/106 (72%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPP 115
[70][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 122 bits (307), Expect = 9e-27
Identities = 60/117 (51%), Positives = 76/117 (64%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ +A A K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG
Sbjct: 1 MHISQKLAQAKAE--GKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGR 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ +T ++ K Q G+ET MHLTCT+M K+D+AL +G N+LALRGDPP
Sbjct: 59 HSKLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPP 115
[71][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 122 bits (307), Expect = 9e-27
Identities = 60/117 (51%), Positives = 81/117 (69%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M V++KI+ D SFEFFPPKT+ G NLL R+ RM A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGS 57
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPP 114
[72][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 122 bits (306), Expect = 1e-26
Identities = 59/117 (50%), Positives = 79/117 (67%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ K+ +A A+D FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MKISHKLEKAHAADSTPT-FSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGR 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ Q+ +G+ET MHLTCT MP + +++AL++ G QN+LALRGDPP
Sbjct: 60 LSNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPP 116
[73][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 122 bits (305), Expect = 2e-26
Identities = 59/117 (50%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M + +K+ E S + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHIGQKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++T ++ + Q G+ET MHLTCT+MP E++D ALE+ + G N+LALRGDPP
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNILALRGDPP 115
[74][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 121 bits (303), Expect = 3e-26
Identities = 58/108 (53%), Positives = 71/108 (65%)
Frame = +1
Query: 109 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 288
A K FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 3 AETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMV 62
Query: 289 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ Q G+ET MHLTCT+M VEK++DAL G N+LALRGDPP
Sbjct: 63 TQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPP 110
[75][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 120 bits (302), Expect = 4e-26
Identities = 56/98 (57%), Positives = 70/98 (71%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q+ G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M +EK++DAL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGLEKVNDALRKGYKAGCTNILALRGDPP 115
[76][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 120 bits (302), Expect = 4e-26
Identities = 62/119 (52%), Positives = 79/119 (66%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 259 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
[77][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 120 bits (302), Expect = 4e-26
Identities = 62/119 (52%), Positives = 79/119 (66%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 259 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
[78][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 120 bits (302), Expect = 4e-26
Identities = 58/98 (59%), Positives = 68/98 (69%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M EK+D+AL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPP 115
[79][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 120 bits (302), Expect = 4e-26
Identities = 58/98 (59%), Positives = 68/98 (69%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M EK+D+AL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPP 115
[80][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 120 bits (302), Expect = 4e-26
Identities = 62/119 (52%), Positives = 79/119 (66%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 259 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPP 118
[81][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 120 bits (300), Expect = 6e-26
Identities = 58/97 (59%), Positives = 68/97 (70%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
S EFFPPKTE G NLLERM+RM A P F +TWGAGGSTA+ TL++A Q + +
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKTLELASLAQKNLNLPI 75
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCTNM IDDAL K+ G+ N+LALRGDPP
Sbjct: 76 CMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPP 112
[82][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 119 bits (299), Expect = 8e-26
Identities = 57/98 (58%), Positives = 69/98 (70%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M VEK++DAL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPP 115
[83][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 119 bits (299), Expect = 8e-26
Identities = 57/98 (58%), Positives = 69/98 (70%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M VEK++DAL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPP 115
[84][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 119 bits (298), Expect = 1e-25
Identities = 54/117 (46%), Positives = 81/117 (69%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P +TWGAGGS
Sbjct: 1 MKLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGS 57
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D +L++A Q ++T++HLTCTNM +D+ L+ ++ G+QN+LALRGDPP
Sbjct: 58 TKDRSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNILALRGDPP 114
[85][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 118 bits (296), Expect = 2e-25
Identities = 55/98 (56%), Positives = 70/98 (71%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M EK+++AL+ G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPP 115
[86][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 118 bits (296), Expect = 2e-25
Identities = 59/117 (50%), Positives = 80/117 (68%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M V+E+I A P++ SFEFFPPKT+ G NLL R+ RM +P F +TWGAGGS
Sbjct: 1 MSVVERIQ---ALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGS 57
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T++ +L++A Q +G+ T++HLTCTN IDDAL K+ G++N+LALRGDPP
Sbjct: 58 TSEKSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPP 114
[87][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 117 bits (294), Expect = 3e-25
Identities = 59/120 (49%), Positives = 75/120 (62%), Gaps = 3/120 (2%)
Frame = +1
Query: 82 MKVIEKIHE---AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 252
M++ +K+ + AA + K FSFEFF PKT GV NL +RMDRM P F DITW A
Sbjct: 1 MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA 60
Query: 253 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
GG + T ++ Q +G+ET MHLTCTNM +D+ALE G +N+LALRGDPP
Sbjct: 61 GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENILALRGDPP 120
[88][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 117 bits (294), Expect = 3e-25
Identities = 55/98 (56%), Positives = 69/98 (70%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T MHLTCT+M EK++DAL G N+LALRGDPP
Sbjct: 78 TCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPP 115
[89][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 117 bits (292), Expect = 5e-25
Identities = 65/134 (48%), Positives = 85/134 (63%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 IPSLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV 213
+PSL L + K K+ +KI AA + FS EFFPPKT G NL R+DRM
Sbjct: 5 VPSLELPPEAAKSHAMDKITDKI---AALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRMA 61
Query: 214 -AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKS 390
A P F ++TWGAGGSTA +L++A+ Q +G+ T +HLTCTNM ID AL+ K+
Sbjct: 62 RALRPLFVNVTWGAGGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAKA 121
Query: 391 NGLQNVLALRGDPP 432
G++N+LALRGDPP
Sbjct: 122 LGIRNILALRGDPP 135
[90][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 116 bits (291), Expect = 7e-25
Identities = 57/105 (54%), Positives = 73/105 (69%)
Frame = +1
Query: 118 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 297
SD + + S EFFPPKTE G NLLERM+RM A P F +TWGAGGST++ TL++A+
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKTLELAQIA 67
Query: 298 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q + V MHLTCTNM I +AL+ +S G++N+LALRGD P
Sbjct: 68 QRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAP 112
[91][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 116 bits (291), Expect = 7e-25
Identities = 54/98 (55%), Positives = 68/98 (69%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCT+M EK++DAL G N+LALRGDPP
Sbjct: 78 ACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPP 115
[92][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 116 bits (291), Expect = 7e-25
Identities = 59/117 (50%), Positives = 81/117 (69%), Gaps = 1/117 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ +K+ D +V +S+E+FPPKT GVVNL R++RM P+F D+TWGAGG
Sbjct: 1 MKITDKLQLPEYRD--RVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGG 58
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
S++D+T I K Q+ G++T MHLTCTNM ++ID+ALE G +N+LALRGDP
Sbjct: 59 SSSDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNILALRGDP 115
[93][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 116 bits (291), Expect = 7e-25
Identities = 56/117 (47%), Positives = 79/117 (67%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ +KI E DP+K ++FEFFPP+T+ G NL+ R+ R+ P ITWGAGGS
Sbjct: 1 MKLSQKIAE---HDPSKPFYTFEFFPPRTDQGTENLIARISRLSTLDPLAISITWGAGGS 57
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T + +LD+A Q+ ++T++HLTCTNM IDD L+ +K G++ +LALRGDPP
Sbjct: 58 TKERSLDLASITQSQHRLDTILHLTCTNMEQGLIDDVLKDVKDRGIETILALRGDPP 114
[94][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 116 bits (290), Expect = 9e-25
Identities = 56/97 (57%), Positives = 70/97 (72%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
S EFFPPKTE G NLLERM RM A P F +TWGAGG+TA+ TL++A +N++ +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 77 CIHLTCTNMSRGIIDEALEACKKIGIRNILALRGDPP 113
[95][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 115 bits (289), Expect = 1e-24
Identities = 57/116 (49%), Positives = 78/116 (67%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 264
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P F +TWGAGG+T
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ TLD+A Q + + T +HLTCTN + ID+AL+ NG++N+LALRGDPP
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPP 114
[96][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 115 bits (288), Expect = 2e-24
Identities = 62/117 (52%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPP 116
[97][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 115 bits (288), Expect = 2e-24
Identities = 62/117 (52%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPP 116
[98][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 114 bits (286), Expect = 3e-24
Identities = 60/117 (51%), Positives = 76/117 (64%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M I K+ A P++ FS EFFPPKT++G+ N R+ RM A P F ITWGAGGS
Sbjct: 1 MSTITKL--IAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGS 58
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +LDIA + Q ++G++ +HLTCTNM ID ALE G+ N+LALRGDPP
Sbjct: 59 TAKKSLDIASECQ-SMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPP 114
[99][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 114 bits (286), Expect = 3e-24
Identities = 61/117 (52%), Positives = 80/117 (68%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPP 116
[100][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 114 bits (286), Expect = 3e-24
Identities = 59/114 (51%), Positives = 73/114 (64%)
Frame = +1
Query: 91 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 270
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 271 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP
Sbjct: 59 KTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPP 112
[101][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 114 bits (285), Expect = 3e-24
Identities = 59/114 (51%), Positives = 73/114 (64%)
Frame = +1
Query: 91 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 270
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 271 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPP 112
[102][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 114 bits (285), Expect = 3e-24
Identities = 59/114 (51%), Positives = 73/114 (64%)
Frame = +1
Query: 91 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 270
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 271 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPP 112
[103][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 114 bits (285), Expect = 3e-24
Identities = 59/114 (51%), Positives = 73/114 (64%)
Frame = +1
Query: 91 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 270
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 271 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPP 112
[104][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 114 bits (285), Expect = 3e-24
Identities = 59/114 (51%), Positives = 73/114 (64%)
Frame = +1
Query: 91 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 270
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 271 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPP 112
[105][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 113 bits (282), Expect = 8e-24
Identities = 60/116 (51%), Positives = 79/116 (68%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM IDDAL+ K+ G++N+LALRGDPP
Sbjct: 61 ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNILALRGDPP 116
[106][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 112 bits (281), Expect = 1e-23
Identities = 60/117 (51%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ EKI AA P FS EFFPPKT+ G VNL R++RM P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPP 116
[107][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 112 bits (280), Expect = 1e-23
Identities = 61/117 (52%), Positives = 79/117 (67%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPP 116
[108][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 112 bits (280), Expect = 1e-23
Identities = 60/116 (51%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 61 AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPP 116
[109][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 112 bits (280), Expect = 1e-23
Identities = 61/117 (52%), Positives = 79/117 (67%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPP 116
[110][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 112 bits (280), Expect = 1e-23
Identities = 61/117 (52%), Positives = 79/117 (67%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 86
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 87 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPP 143
[111][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 112 bits (279), Expect = 2e-23
Identities = 63/134 (47%), Positives = 85/134 (63%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 IPSLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV 213
+PSL L + + K+ K+ +KI AA S EFFPPKT G NL +R+DRM
Sbjct: 5 LPSLELPVEAGKNHAMDKITDKI---AALPAETNYCSLEFFPPKTAMGFSNLRDRLDRMA 61
Query: 214 -AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKS 390
A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM + ID LE K+
Sbjct: 62 RALRPLFVNVTWGAGGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAKA 121
Query: 391 NGLQNVLALRGDPP 432
G++N+LALRGDPP
Sbjct: 122 LGIRNILALRGDPP 135
[112][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 111 bits (278), Expect = 2e-23
Identities = 58/116 (50%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGST 264
+EKI + AA P+ FS EFFPPKT G NL +R++RM P F ++TWGAGGST
Sbjct: 1 MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM +D LE K G++N+LALRGDPP
Sbjct: 61 AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPP 116
[113][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 111 bits (278), Expect = 2e-23
Identities = 59/117 (50%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP 116
[114][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 111 bits (278), Expect = 2e-23
Identities = 60/117 (51%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA N FS EFFPPKT G NL +R+DRM A P F ++TWGAGGS
Sbjct: 3 KITDKI---AALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q +G+ T +HLTCTNM +D AL+ K G++N+LALRGDPP
Sbjct: 60 TAFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPP 116
[115][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 111 bits (278), Expect = 2e-23
Identities = 59/117 (50%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 51 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 107
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 108 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP 164
[116][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 111 bits (277), Expect = 3e-23
Identities = 58/116 (50%), Positives = 80/116 (68%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
++KI + A+ P + FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ +L++A+ Q VG+ T +HLTCTNM + ID+AL K+ G++N+LALRGDPP
Sbjct: 61 SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPP 116
[117][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 110 bits (276), Expect = 4e-23
Identities = 54/101 (53%), Positives = 68/101 (67%), Gaps = 1/101 (0%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGGSTADVTLDIAKKMQNT 306
KV +S+EFFPPKT GV NL R+DRM P F D+TWGAGG+++++T I +Q
Sbjct: 15 KVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTD 74
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
V+T MHLTCTNM E ID AL+ G +N+LALRGDP
Sbjct: 75 FEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDP 115
[118][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 110 bits (275), Expect = 5e-23
Identities = 59/117 (50%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP 116
[119][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 110 bits (274), Expect = 6e-23
Identities = 54/105 (51%), Positives = 69/105 (65%)
Frame = +1
Query: 118 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 297
S+ N+ S EFFPPKT+ G NLL R++RM A P F +TWGAGGSTA+ TL++A
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEKTLELAALA 68
Query: 298 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
Q + + MHLTCTNM +D AL K G++N+LALRGD P
Sbjct: 69 QRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNILALRGDMP 113
[120][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 110 bits (274), Expect = 6e-23
Identities = 59/116 (50%), Positives = 78/116 (67%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + A+ P N FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPP 116
[121][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 110 bits (274), Expect = 6e-23
Identities = 61/117 (52%), Positives = 80/117 (68%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI EA D + FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KISDKI-EALPKDAH--YFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q +G+ T +HLTCTNM ID+ALE K+ G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPP 116
[122][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 110 bits (274), Expect = 6e-23
Identities = 59/117 (50%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ EKI AA P+ FS EFFPPKT G NL R++RM A P F +TWGAGGS
Sbjct: 4 KITEKI---AALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS 60
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T++HLTCTNM + +D AL+ K G++N+LALRGDPP
Sbjct: 61 TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPP 117
[123][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 110 bits (274), Expect = 6e-23
Identities = 60/117 (51%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPP 116
[124][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 109 bits (273), Expect = 8e-23
Identities = 59/117 (50%), Positives = 77/117 (65%), Gaps = 1/117 (0%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
TA +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPP 116
[125][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 109 bits (272), Expect = 1e-22
Identities = 58/116 (50%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPP 116
[126][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 109 bits (272), Expect = 1e-22
Identities = 58/116 (50%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPP 116
[127][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 109 bits (272), Expect = 1e-22
Identities = 60/116 (51%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + S P+ FS EFFPPKT G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM + IDDALE K G++N+LALRGD P
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAP 116
[128][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 108 bits (271), Expect = 1e-22
Identities = 54/99 (54%), Positives = 71/99 (71%), Gaps = 1/99 (1%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST+ +L++A+ Q +G+
Sbjct: 18 FSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGSTSQKSLELAELCQRELGL 77
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T +HLTCTNM + ID ALE K+ G++N+LALRGDPP
Sbjct: 78 TTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPP 116
[129][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 108 bits (271), Expect = 1e-22
Identities = 58/116 (50%), Positives = 78/116 (67%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPP 116
[130][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 108 bits (271), Expect = 1e-22
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F ++TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPP 116
[131][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 108 bits (271), Expect = 1e-22
Identities = 58/116 (50%), Positives = 78/116 (67%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPP 116
[132][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 108 bits (271), Expect = 1e-22
Identities = 58/116 (50%), Positives = 78/116 (67%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPP 116
[133][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 108 bits (269), Expect = 2e-22
Identities = 51/100 (51%), Positives = 75/100 (75%), Gaps = 3/100 (3%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVA---HSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 312
++EFFPP T+ G VNLL+R+ R+ + +P +TWGAGGSTA+ +L++A+++ + +G
Sbjct: 17 NYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGSTAEKSLELAQQVVD-MG 75
Query: 313 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
VE ++HLTCTNMP +K+D AL K G+ N+LALRGDPP
Sbjct: 76 VEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPP 115
[134][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 108 bits (269), Expect = 2e-22
Identities = 56/116 (48%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPP 116
[135][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 107 bits (267), Expect = 4e-22
Identities = 56/116 (48%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 91 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 264
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST 60
Query: 265 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP
Sbjct: 61 VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPP 116
[136][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 106 bits (265), Expect = 7e-22
Identities = 55/118 (46%), Positives = 79/118 (66%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 258
M+ I I+ AA +D ++ V SFEFFPPKT++G LLE+ + ++ P FC +T+GAGG
Sbjct: 7 MQFIRDIY-AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGG 65
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D TL I ++Q + TM+HLTC N E++ D +E +S G++N+LALRGDPP
Sbjct: 66 GTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNILALRGDPP 123
[137][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 106 bits (265), Expect = 7e-22
Identities = 52/96 (54%), Positives = 66/96 (68%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
S EFFPPKTE G NLL RM+RM A +P F +TW AGG+TA TL++A Q + V
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
MHLTCTNM + ID+AL+ + ++N+LALRGDP
Sbjct: 87 CMHLTCTNMNKDIIDEALKAARDADIRNILALRGDP 122
[138][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 104 bits (260), Expect = 3e-21
Identities = 53/97 (54%), Positives = 64/97 (65%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
S EFFPPKT+ G NL RM RM A +P F ITWGAGG+TA TL++A Q + V
Sbjct: 36 SLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTAKKTLELATVAQRELNVPV 95
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
MHLTCTN E ID+AL+ ++N+LALRGDPP
Sbjct: 96 CMHLTCTNTNKEIIDEALKLAHEADIRNILALRGDPP 132
[139][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 104 bits (259), Expect = 3e-21
Identities = 49/106 (46%), Positives = 70/106 (66%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A + + VFSFEFFPPKT+DGV L E ++ + +P++ +T+GAGGST TL++ K+
Sbjct: 10 ARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQRTLELVKR 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ VE M HLTC E++ L+ + G+QNVLALRGDPP
Sbjct: 70 LKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPP 115
[140][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 103 bits (258), Expect = 5e-21
Identities = 45/104 (43%), Positives = 70/104 (67%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 300
+P+ FSFEFFPPKT++G NLL+ ++ + P F +T+GAGGST + TL + +++
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 301 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T G+E+M HLTC +++ + L+ +++ L NVL LRGDPP
Sbjct: 105 QTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNVLVLRGDPP 148
[141][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 103 bits (256), Expect = 8e-21
Identities = 55/118 (46%), Positives = 77/118 (65%), Gaps = 6/118 (5%)
Frame = +1
Query: 97 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPS-FCDITWGAGGSTADV 273
KI + D S E+FPP+T+ GV NL RMDRM+ ++ + + D+TWGAGGSTAD+
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTADL 71
Query: 274 TLDIAKKMQNTVGVETMMHLTCTNM-----PVEKIDDALETIKSNGLQNVLALRGDPP 432
+L++A T G + MHLTCTNM PV+ + DAL+ G++N++ALRGDPP
Sbjct: 72 SLELALHAHKT-GHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPP 128
[142][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 103 bits (256), Expect = 8e-21
Identities = 51/99 (51%), Positives = 65/99 (65%), Gaps = 1/99 (1%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
+SFEFFPPKTE G+ NLL R+DRM P F ITWG+ GST TL +A Q V
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV 60
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++HL+CT + E+I L KS+G+ N+LALRGDPP
Sbjct: 61 DVLLHLSCTGLTREQIGHVLAMAKSSGVHNILALRGDPP 99
[143][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 102 bits (255), Expect = 1e-20
Identities = 53/119 (44%), Positives = 71/119 (59%), Gaps = 4/119 (3%)
Frame = +1
Query: 88 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 267
+IEKIH+ K FS EFFPP+T +G VNL+ R DRM P FCDITW G +
Sbjct: 21 LIEKIHKHIGK--KKKFFSLEFFPPRTPNGAVNLVARFDRMSQGGPLFCDITWHPAGDPS 78
Query: 268 ----DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ IA N G+ETM+H+TC N+ + + L+ K+ G++N+LALRGDPP
Sbjct: 79 GDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKKAKNLGIRNILALRGDPP 137
[144][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 102 bits (255), Expect = 1e-20
Identities = 54/118 (45%), Positives = 74/118 (62%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 258
M+ I I+ A A + V S EFFP KTE+G NLLE+ + +++ P+FC +T+GAGG
Sbjct: 1 MQFIRDIY-AEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGG 59
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D TL I ++Q + MMHLTC N E++ L+ K G+QN+LALRGDPP
Sbjct: 60 GTRDKTLGIVDRIQRHHNLPAMMHLTCVNSTREELGHVLDEAKGRGIQNILALRGDPP 117
[145][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 102 bits (255), Expect = 1e-20
Identities = 54/119 (45%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAG 255
MK+++ I + PN +SFE+FPPKT G+ NL R+ RM + P F +TWG
Sbjct: 1 MKIVDLIDKI----PNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTA 56
Query: 256 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
GSTA+V++ +AK ++ + +HLTCTN+ ID ALET K G++N+LALRGDPP
Sbjct: 57 GSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPP 115
[146][TOP]
>UniRef100_B6FS52 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FS52_9CLOT
Length = 288
Score = 102 bits (253), Expect = 2e-20
Identities = 50/117 (42%), Positives = 74/117 (63%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ +++ E N+V SFE FPPKT+ G +LE + + A PSF +T+GAGG
Sbjct: 1 MKIKDRLSE------NRVNISFEVFPPKTDAGYGKVLEATEEIAALKPSFISVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ T+ IA +QN +GV ++ HLTC + E++ +E +K G+QN+LALRGD P
Sbjct: 55 TSKNTVKIASHIQNDLGVASLAHLTCASSTKEEVRQVIEQLKEQGIQNILALRGDIP 111
[147][TOP]
>UniRef100_A5KL25 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus torques
ATCC 27756 RepID=A5KL25_9FIRM
Length = 289
Score = 102 bits (253), Expect = 2e-20
Identities = 47/117 (40%), Positives = 76/117 (64%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+++ E +K+ SFE FPPKT+ G ++ D M +P+F +T+GAGG
Sbjct: 1 MKIIDRLKE------DKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ T IA +++ +GV ++ HLTC + +E++ D +E +K NG++N+LALRGD P
Sbjct: 55 TSKNTAKIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIP 111
[148][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 101 bits (251), Expect = 3e-20
Identities = 46/106 (43%), Positives = 69/106 (65%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ VE M H+TC ++I L+ + G+QNVLALRGDPP
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPP 115
[149][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 101 bits (251), Expect = 3e-20
Identities = 46/106 (43%), Positives = 69/106 (65%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ VE M H+TC ++I L+ + G+QNVLALRGDPP
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPP 115
[150][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 100 bits (250), Expect = 4e-20
Identities = 47/106 (44%), Positives = 68/106 (64%)
Frame = +1
Query: 115 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 294
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+D+ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIDLVKR 69
Query: 295 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ VE M H+TC E+I L+ + G+QNVLALRGD P
Sbjct: 70 LKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAP 115
[151][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 99.8 bits (247), Expect = 9e-20
Identities = 48/112 (42%), Positives = 70/112 (62%)
Frame = +1
Query: 97 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVT 276
KIH A P K +FSFEFFPPKTE+G L + + P+F +T+GAGGS T
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++ ++++ VG+E M HLTC E+I + LE ++ G +N++A+RGDPP
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAVRGDPP 111
[152][TOP]
>UniRef100_UPI000196BD8E hypothetical protein CATMIT_02257 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196BD8E
Length = 287
Score = 99.0 bits (245), Expect = 1e-19
Identities = 47/117 (40%), Positives = 74/117 (63%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+ ++E +KV SFE FPPKT N+L+ +++ + +P+F +T+GAGG
Sbjct: 1 MKIIDLLNE------DKVTLSFEVFPPKTSGRYENVLKAAEKIASLNPNFMSVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ T+ +AK + GVE M HLTC + E ++ +E K NG++N++ALRGD P
Sbjct: 55 TSAHTVALAKDIHEKYGVEVMAHLTCVSSTKEHVESMVEQFKENGIENIMALRGDIP 111
[153][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 98.2 bits (243), Expect = 3e-19
Identities = 47/109 (43%), Positives = 70/109 (64%), Gaps = 2/109 (1%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLE-RMDRMVAHSPSFCDITWGAGGSTADVTLDIA 288
AA D NK S+EF+PP++E N ++ ++ + SP F D+TWGAGG T++ T+ +
Sbjct: 10 AAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGRTSETTMRLC 69
Query: 289 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
K +QN MH+TCTNM + I + L+ K +G++N+LALRGDPP
Sbjct: 70 KDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPP 118
[154][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 98.2 bits (243), Expect = 3e-19
Identities = 44/75 (58%), Positives = 55/75 (73%)
Frame = +1
Query: 208 MVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIK 387
M A P F DITW AGG T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL+ K
Sbjct: 1 MRALGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAK 60
Query: 388 SNGLQNVLALRGDPP 432
+G +N+LALRGDPP
Sbjct: 61 EHGCRNILALRGDPP 75
[155][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 97.8 bits (242), Expect = 3e-19
Identities = 44/101 (43%), Positives = 66/101 (65%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
K V SFE FPPK + + ++ +++ P F +T+GAGGS D T++IA K++N
Sbjct: 11 KPVISFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTIEIASKIKNEY 70
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+E+M HLTC E+ID L +++ + L+N+LALRGDPP
Sbjct: 71 GIESMAHLTCVGHSKEEIDALLTSMREHNLENILALRGDPP 111
[156][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 95.9 bits (237), Expect = 1e-18
Identities = 49/117 (41%), Positives = 68/117 (58%), Gaps = 4/117 (3%)
Frame = +1
Query: 88 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW----GAG 255
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P F D+TW +G
Sbjct: 26 IIQKIRKRINSGDK--FYSLEFFPPRTDSGGVNLIARFDRLAIGNPLFIDVTWHPKGNSG 83
Query: 256 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
G +L IA N G+++M+H+TC N E ID L K GL+N+LALRGD
Sbjct: 84 GDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNILALRGD 140
[157][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 95.9 bits (237), Expect = 1e-18
Identities = 49/118 (41%), Positives = 73/118 (61%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 258
MK+ E++ + D + +SFEFFPPKT G+ NL RM RM P F +TW + G
Sbjct: 1 MKISEQLEQLPKDD---IHYSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAG 57
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
S+A +L + +Q+ GV + +H+TC+N+ E I L+ K+ G++N+LALRGDPP
Sbjct: 58 SSAAESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNILALRGDPP 115
[158][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 95.5 bits (236), Expect = 2e-18
Identities = 43/98 (43%), Positives = 63/98 (64%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFEFFPPKTE+ NL + ++ P FC +T+GAGGST + T + A ++Q T G+E
Sbjct: 15 FSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETALEIQQTTGIE 74
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
HL+C I + LE +S+G+++++ALRGD P
Sbjct: 75 CAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMP 112
[159][TOP]
>UniRef100_C0C3T3 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium hylemonae
DSM 15053 RepID=C0C3T3_9CLOT
Length = 289
Score = 95.5 bits (236), Expect = 2e-18
Identities = 43/97 (44%), Positives = 65/97 (67%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T++IA +QN +GV +
Sbjct: 15 SFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTVNIASHIQNDLGVVS 74
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ HLTC + E++ +E +K G++NVL LRGD P
Sbjct: 75 LAHLTCASSTKEEVHQVIEKLKEKGIENVLGLRGDIP 111
[160][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 95.1 bits (235), Expect = 2e-18
Identities = 48/117 (41%), Positives = 68/117 (58%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+K+ K+ SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KISISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T + T DI KK+ + M HLTC ++I L+ K G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENILALRGDMP 111
[161][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 94.7 bits (234), Expect = 3e-18
Identities = 50/101 (49%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+E+++HLTC N EKI D L K GL+N++ALRGDP
Sbjct: 120 CGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDP 160
[162][TOP]
>UniRef100_B0N2P6 Methylenetetrahydrofolate reductase n=2 Tax=Bacteria
RepID=B0N2P6_9FIRM
Length = 296
Score = 94.7 bits (234), Expect = 3e-18
Identities = 45/118 (38%), Positives = 74/118 (62%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 258
MK+I+ +H + SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHR-------RPTLSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGG 53
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
ST + T++IA K++N +E + HL+C + E++ L+++K+N ++NVLALRGD P
Sbjct: 54 STTENTVEIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENVLALRGDYP 111
[163][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 94.4 bits (233), Expect = 4e-18
Identities = 47/117 (40%), Positives = 72/117 (61%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+++K+ + KV SFEFFPPKT++ +L + ++ + +P+F +T+GAGGS
Sbjct: 1 MKIVDKLKK------EKVSISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGS 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T + T DI KK+ + M HLTC ++I LE K+ G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENILALRGDIP 111
[164][TOP]
>UniRef100_A1VEZ2 Methylenetetrahydrofolate reductase n=3 Tax=Desulfovibrio vulgaris
RepID=A1VEZ2_DESVV
Length = 291
Score = 94.4 bits (233), Expect = 4e-18
Identities = 48/117 (41%), Positives = 67/117 (57%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ E I + + +S EFFPPK + ++R+ A P F +T+GAGG
Sbjct: 1 MKIAEAIERQS-----RPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGG 55
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D TLDI ++N +G+E M HLTC E+I L ++ G++NVLALRGDPP
Sbjct: 56 TQDNTLDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPP 112
[165][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 94.4 bits (233), Expect = 4e-18
Identities = 45/102 (44%), Positives = 61/102 (59%), Gaps = 4/102 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA----DVTLDIAKKMQNT 306
FS EFFPP+T +G VNLL DR+ + P FCD+TW G + ++ IA N
Sbjct: 12 FSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTSSMTIASTALNY 71
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+ETM+H+TC N + L K+ G++N+LALRGDPP
Sbjct: 72 CGLETMLHMTCANQTKASVTKNLHKAKTLGIRNILALRGDPP 113
[166][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 94.0 bits (232), Expect = 5e-18
Identities = 42/111 (37%), Positives = 65/111 (58%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTL 279
+H + + SFEFFPPK E+ +L + + +P++ +T+GAGGST +T
Sbjct: 1 MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH 60
Query: 280 DIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
D+ K+QN G+ + HLTC E+I D L+ +G+ N++ALRGDPP
Sbjct: 61 DLVVKLQNETGLTIVSHLTCVGSTKEEIGDILKRYDKSGIHNIMALRGDPP 111
[167][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 93.2 bits (230), Expect = 8e-18
Identities = 46/117 (39%), Positives = 69/117 (58%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK + +I+ +A V+SFEFFPPKT+DG + L+ + + P F +T+GAGGS
Sbjct: 1 MKKVSEIYGSAKGP----VYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGS 56
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D T I ++ T+ H TC ++I L+ I+S+G+ N++ALRGDPP
Sbjct: 57 TRDKTAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPP 113
[168][TOP]
>UniRef100_A6NZH7 Methylenetetrahydrofolate reductase n=1 Tax=Bacteroides capillosus
ATCC 29799 RepID=A6NZH7_9BACE
Length = 286
Score = 93.2 bits (230), Expect = 8e-18
Identities = 47/117 (40%), Positives = 69/117 (58%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+ + + +KV SFE FPPKT D ++ + + A P F +T+GAGG
Sbjct: 1 MKIIDILSQ------DKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+D T+ IA +++ GVE + HLTC + E + L +K +G+ NVLALRGD P
Sbjct: 55 TSDYTVGIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNVLALRGDIP 111
[169][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 93.2 bits (230), Expect = 8e-18
Identities = 45/109 (41%), Positives = 71/109 (65%), Gaps = 2/109 (1%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERM-DRMVAHSPSFCDITWGAGGSTADVTLDIA 288
AA D +K S+E +PP++E ++++ + + SP F D+TWGAGG T+D T+ +
Sbjct: 10 AAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGRTSDTTMRLC 69
Query: 289 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
K +Q+ MH+TCTN P I++AL+ K++G++N+LALRGDPP
Sbjct: 70 KDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPP 118
[170][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 92.8 bits (229), Expect = 1e-17
Identities = 42/104 (40%), Positives = 64/104 (61%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 300
+P+ FSFEFFPP+T++G NLL+ ++ + P F +T GAGGST T+++ +++
Sbjct: 8 NPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRIK 67
Query: 301 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+E M HLTC ++ LE + + + NVL LRGDPP
Sbjct: 68 QEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPP 111
[171][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 92.8 bits (229), Expect = 1e-17
Identities = 44/105 (41%), Positives = 63/105 (60%)
Frame = +1
Query: 118 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 297
S + +FSFEFFPPK D L + ++ +PS+ +T+GAGGST T D+ K+
Sbjct: 8 SSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRTHDLVTKI 67
Query: 298 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ G+ + HLTC ++I D L T ++NG+ NVLALRGD P
Sbjct: 68 RKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLP 112
[172][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 92.8 bits (229), Expect = 1e-17
Identities = 48/117 (41%), Positives = 68/117 (58%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+K+ KV SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KVSISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T + T DI KK+ + M HLTC ++I L+ + G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENILALRGDIP 111
[173][TOP]
>UniRef100_A4J6K4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfotomaculum
reducens MI-1 RepID=A4J6K4_DESRM
Length = 288
Score = 92.8 bits (229), Expect = 1e-17
Identities = 42/99 (42%), Positives = 61/99 (61%)
Frame = +1
Query: 136 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
V SFE FPPK+ V + E ++ ++ P F +T+GAGGS+ D T +IA ++N +
Sbjct: 13 VISFEIFPPKSTSPVETIYETLEGLIKLEPGFISVTYGAGGSSRDRTKEIAATIKNRYKI 72
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
E + HLTC V +ID L ++ ++NVLALRGDPP
Sbjct: 73 EALAHLTCVGQAVNEIDQILNELQEENIENVLALRGDPP 111
[174][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/99 (46%), Positives = 66/99 (66%), Gaps = 1/99 (1%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
+SFEFFPPKTE G+ NLL R+DRM P F D+TWG+ ++A T+ +A Q +GV
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPLFIDVTWGSDKTSAR-TMALASHAQKYLGV 99
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++HL+C M +++ L+ K G+ N+LALRGDPP
Sbjct: 100 DVLLHLSCQGMTRDQLIRVLDQAKVLGIHNILALRGDPP 138
[175][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/87 (52%), Positives = 62/87 (71%), Gaps = 1/87 (1%)
Frame = +1
Query: 175 GVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMP 351
G NL +R+DRM A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM
Sbjct: 2 GFSNLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELALTTCLHLTCTNMS 61
Query: 352 VEKIDDALETIKSNGLQNVLALRGDPP 432
+ ID ALE K+ G++N+LALRGDPP
Sbjct: 62 RKLIDKALEDAKALGIRNILALRGDPP 88
[176][TOP]
>UniRef100_B8DJ94 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio vulgaris
str. 'Miyazaki F' RepID=B8DJ94_DESVM
Length = 291
Score = 92.4 bits (228), Expect = 1e-17
Identities = 49/117 (41%), Positives = 70/117 (59%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+ ++I AA++ P +S EFFPPK + ++R+ A P F +T+GAGGS
Sbjct: 1 MKIRDRI--AASTRP---FYSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGS 55
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D TL+I ++N +G+E M HLTC E+I D L ++ + NVLALRGD P
Sbjct: 56 TQDNTLEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAP 112
[177][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 92.0 bits (227), Expect = 2e-17
Identities = 47/106 (44%), Positives = 61/106 (57%), Gaps = 4/106 (3%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 300
+ N FS EFFPP+TE G NL+ R DRM A P F DITW G + + K+
Sbjct: 27 ESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGGPLFVDITWHPAGDPGSDKITSSTKIA 86
Query: 301 NTV----GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
TV G++TM+H+TC E I LE K+ G++N+LALRGD
Sbjct: 87 GTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKNLGIRNILALRGD 132
[178][TOP]
>UniRef100_A9KQY7 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
phytofermentans ISDg RepID=A9KQY7_CLOPH
Length = 286
Score = 92.0 bits (227), Expect = 2e-17
Identities = 44/100 (44%), Positives = 62/100 (62%), Gaps = 1/100 (1%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNT 306
K VFS E FPPK + V ++ + + +P F +T+GAGG+ AD T DIA +Q+
Sbjct: 11 KTVFSLEVFPPKKDSPVESIYRVLGELTKLNPDFISVTYGAGGNAADHTTCDIASYIQSN 70
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
G++ + HLTC N E +D LE +KS G+ N+LALRGD
Sbjct: 71 YGIDALTHLTCVNSTKEDMDTTLEYLKSQGIMNILALRGD 110
[179][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 92.0 bits (227), Expect = 2e-17
Identities = 43/98 (43%), Positives = 62/98 (63%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPK E+G L + + + P+F +T+GAGGST D T ++ K++ VG+
Sbjct: 15 SFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTRNVVKRIHEEVGLTV 74
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 435
M HLTC E++ + LE + G++N+LALRGD PH
Sbjct: 75 MAHLTCIAHTREELIEILEDYRGIGIENILALRGDVPH 112
[180][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 91.7 bits (226), Expect = 2e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 125 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDP 165
[181][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 91.7 bits (226), Expect = 2e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDP 200
[182][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 91.7 bits (226), Expect = 2e-17
Identities = 46/117 (39%), Positives = 70/117 (59%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPP 130
[183][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 91.7 bits (226), Expect = 2e-17
Identities = 46/117 (39%), Positives = 70/117 (59%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPP 130
[184][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 91.7 bits (226), Expect = 2e-17
Identities = 44/97 (45%), Positives = 63/97 (64%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPKTE+G L E + ++ +P+F +T+GAGGST D T +I +K+ +
Sbjct: 15 SFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTRNIVQKIHEETNLTV 74
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
M HLTC E++ D L+ K+ G++N+LALRGD P
Sbjct: 75 MAHLTCIAHTREELIDILQDYKNIGIENILALRGDVP 111
[185][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 143 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 183
[186][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 161 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 201
[187][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 143 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 183
[188][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 161 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 201
[189][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[190][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[191][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[192][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[193][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[194][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 120 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 160
[195][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 149
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 150 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 190
[196][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[197][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 120 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 160
[198][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 90.9 bits (224), Expect = 4e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC N E I L+ K GL+N++ALRGDP
Sbjct: 114 CGLETLLHMTCCNQTKEDITKHLQKAKRLGLKNIMALRGDP 154
[199][TOP]
>UniRef100_B3E425 Methylenetetrahydrofolate reductase n=1 Tax=Geobacter lovleyi SZ
RepID=B3E425_GEOLS
Length = 290
Score = 90.9 bits (224), Expect = 4e-17
Identities = 41/97 (42%), Positives = 61/97 (62%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
S E+FPPK + ++R+ + +P F +T+GAGGS D TL+I +MQ +G+ET
Sbjct: 15 SVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATLEIVTQMQQQLGLET 74
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
M HLTC +++ L+ + G+QN+LALRGDPP
Sbjct: 75 MAHLTCVGAQAGRLNRFLDDLSKVGIQNILALRGDPP 111
[200][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 90.9 bits (224), Expect = 4e-17
Identities = 43/70 (61%), Positives = 49/70 (70%)
Frame = +1
Query: 223 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 402
P F DITW AGG T+D+T + K +Q GVET MHLTCTNMP KI+ AL K G +
Sbjct: 6 PEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAKEFGCR 65
Query: 403 NVLALRGDPP 432
NVLALRGDPP
Sbjct: 66 NVLALRGDPP 75
[201][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDP 164
[202][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC + E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDP 159
[203][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDP 164
[204][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC + E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDP 159
[205][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 90.1 bits (222), Expect = 7e-17
Identities = 43/88 (48%), Positives = 60/88 (68%), Gaps = 2/88 (2%)
Frame = +1
Query: 175 GVVNLLERMDRMVAHSPSFCDITWGAGG--STADVTLDIAKKMQNTVGVETMMHLTCTNM 348
GV NL ER+DRM P + D+TWGAGG S+++ T +I + G++ MMHLTCT+
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTHQ 61
Query: 349 PVEKIDDALETIKSNGLQNVLALRGDPP 432
VE+ID+ L+ K G++N+LALRGD P
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAP 89
[206][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC N E I L K GL+N++ALRGDP
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDP 154
[207][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 89.7 bits (221), Expect = 9e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDP 164
[208][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC N E I L K GL+N++ALRGDP
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDP 154
[209][TOP]
>UniRef100_B5CM26 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus lactaris
ATCC 29176 RepID=B5CM26_9FIRM
Length = 289
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/117 (35%), Positives = 72/117 (61%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I++++E +++ SFE FPPKT+ G N+ D + PS+ +T+GAGG
Sbjct: 1 MKIIDRLNE------DRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ T IA +++ + V ++ HLTC + E++ + + +K G++N+LALRGD P
Sbjct: 55 TSKNTAKIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIP 111
[210][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 89.7 bits (221), Expect = 9e-17
Identities = 43/88 (48%), Positives = 59/88 (67%), Gaps = 2/88 (2%)
Frame = +1
Query: 175 GVVNLLERMDRMVAHSPSFCDITWGAGGSTA--DVTLDIAKKMQNTVGVETMMHLTCTNM 348
GV NL ER+DRM P + D+TWGAGGS++ + T +I + G++ MMHLTCT
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQQ 61
Query: 349 PVEKIDDALETIKSNGLQNVLALRGDPP 432
VE+ID+ L+ K G++N+LALRGD P
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAP 89
[211][TOP]
>UniRef100_UPI0001794577 hypothetical protein CLOSPO_03313 n=1 Tax=Clostridium sporogenes
ATCC 15579 RepID=UPI0001794577
Length = 336
Score = 89.0 bits (219), Expect = 2e-16
Identities = 42/113 (37%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = +1
Query: 97 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-V 273
++H + +VFSFE FPPK V + E ++ + +P F +T+GAGGS D
Sbjct: 41 RMHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNK 100
Query: 274 TLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T +++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 101 TCELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIP 153
[212][TOP]
>UniRef100_C7IBI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7IBI3_9CLOT
Length = 286
Score = 89.0 bits (219), Expect = 2e-16
Identities = 42/100 (42%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNT 306
K V SFE FPPK + + ++ E + + SP F +T+GAGGS+ + T++IAKK+++
Sbjct: 11 KPVLSFEIFPPKRDSELKDIDETLAILSKLSPDFISVTFGAGGSSNNNKTIEIAKKIKHQ 70
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
G+ET++HLTC+ ++ID + + NG++N+LALRGD
Sbjct: 71 YGIETLVHLTCSGYTKQEIDSFISILSENGIENILALRGD 110
[213][TOP]
>UniRef100_C1XL88 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus ruber DSM
1279 RepID=C1XL88_MEIRU
Length = 291
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/101 (43%), Positives = 60/101 (59%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
K +FSFEFFPPKT G L + + P+F IT+GAGGS + T + A ++QN V
Sbjct: 11 KPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTAEWAARIQNEV 70
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+ M HLTC E++ L G++N++ALRGDPP
Sbjct: 71 GLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPP 111
[214][TOP]
>UniRef100_C6BWS6 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
salexigens DSM 2638 RepID=C6BWS6_DESAD
Length = 290
Score = 88.6 bits (218), Expect = 2e-16
Identities = 43/117 (36%), Positives = 67/117 (57%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
MK+I+ I++ N S EFFPPK + E +D++ +P F +T+GAGG
Sbjct: 1 MKIIDLINK------NGQFISLEFFPPKDRESWPKFFEVVDKLKVLNPLFASVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D +L+I K+M+ G+E + HLTC E I + + ++ ++N+LALRGD P
Sbjct: 55 TQDNSLEIVKRMKQDAGIEPLAHLTCVGASPENISEFVSALQEADVENILALRGDAP 111
[215][TOP]
>UniRef100_C6JIG2 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium varium
ATCC 27725 RepID=C6JIG2_FUSVA
Length = 293
Score = 88.6 bits (218), Expect = 2e-16
Identities = 39/101 (38%), Positives = 63/101 (62%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
K + SFE FPP + + ++ +D + P F +T+GAGG+T T++IA K++N
Sbjct: 11 KTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTVEIASKIKNNN 70
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+E + HLTC +IDD L+ +++N ++N+LALRGD P
Sbjct: 71 KIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKP 111
[216][TOP]
>UniRef100_C5RR04 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
cellulovorans 743B RepID=C5RR04_CLOCL
Length = 285
Score = 88.6 bits (218), Expect = 2e-16
Identities = 41/102 (40%), Positives = 63/102 (61%)
Frame = +1
Query: 127 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 306
N+ FS E FPPK D N++ +D + F +T+GAGGS+ D T+ ++KK+++
Sbjct: 9 NRQSFSVELFPPKKTDSFDNIINTLDNLNGLDIDFVSVTYGAGGSSRDNTVKLSKKIKSE 68
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+E + HLTC N ++I L+ +K N L+N+LALRGD P
Sbjct: 69 YNLEVITHLTCINSKKDEIASLLDEMKENNLENILALRGDIP 110
[217][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 88.6 bits (218), Expect = 2e-16
Identities = 44/98 (44%), Positives = 60/98 (61%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFEFFPPKTE G + L D + A +P F +T+GAGGST D TL+ + G+
Sbjct: 40 FSFEFFPPKTEQGKIKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETVFSLHQQ-GIS 98
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T HL+C +I + L+T K+NG+ ++ALRGD P
Sbjct: 99 TAPHLSCVGGTRAEISELLDTYKANGINRIVALRGDLP 136
[218][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 88.6 bits (218), Expect = 2e-16
Identities = 45/109 (41%), Positives = 68/109 (62%), Gaps = 2/109 (1%)
Frame = +1
Query: 112 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIA 288
AA D +K S+E +PP++E ++++ + H SP F D+TWGAGG T+ T+ +
Sbjct: 10 AAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGRTSGTTMRLC 69
Query: 289 KKMQNT-VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
K +Q+ MH+TCTN P I + LE K++G++N+LALRGDPP
Sbjct: 70 KDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNILALRGDPP 118
[219][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/121 (40%), Positives = 68/121 (56%), Gaps = 5/121 (4%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
+K+ ++I A D + FS EFFPP+T G NL+ R +RMV P F DITW G
Sbjct: 30 VKLADRIE--AKIDRGERWFSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGD 87
Query: 262 TAD-----VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
+ ++ IA N VG ETM+H++C N + I L+ K G++N+LALRGD
Sbjct: 88 PGNSDKETSSMSIACAALNYVGHETMLHMSCCNSTKDDIRRHLDKAKELGIRNILALRGD 147
Query: 427 P 429
P
Sbjct: 148 P 148
[220][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 88.2 bits (217), Expect = 3e-16
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETVLHMTCCRQSREEITGYLHKAKRLGLKNILALRGDP 159
[221][TOP]
>UniRef100_B1ILP1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
B1 str. Okra RepID=B1ILP1_CLOBK
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[222][TOP]
>UniRef100_A7GDU9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum F
str. Langeland RepID=A7GDU9_CLOBL
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[223][TOP]
>UniRef100_A1BH63 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BH63_CHLPD
Length = 289
Score = 88.2 bits (217), Expect = 3e-16
Identities = 43/99 (43%), Positives = 58/99 (58%)
Frame = +1
Query: 136 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
VFSFEFFPPK E+ L + + + +PS+ +T+GAGGST T D+ ++Q G+
Sbjct: 14 VFSFEFFPPKKEEEWNTLFATIASLTSLNPSYVSVTYGAGGSTRSKTHDLVTRIQKETGI 73
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ HLTC E+ LE NG+ NVLALRGD P
Sbjct: 74 TVVSHLTCVCSDREETSSILENYLENGINNVLALRGDKP 112
[224][TOP]
>UniRef100_Q0YRM1 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YRM1_9CHLB
Length = 328
Score = 88.2 bits (217), Expect = 3e-16
Identities = 46/115 (40%), Positives = 68/115 (59%)
Frame = +1
Query: 88 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 267
++++I +AA K VFSFEFFPPK ++ L + + + +PS+ +T+GAGGST
Sbjct: 41 LVKEILDAAV----KPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTR 96
Query: 268 DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T D+ K+Q G+ + HLTC E+ L+ + NG+ NVLALRGD P
Sbjct: 97 SRTHDLVTKIQRETGLTVVSHLTCICSDREETGSILQNYRDNGINNVLALRGDKP 151
[225][TOP]
>UniRef100_B1QD70 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
NCTC 2916 RepID=B1QD70_CLOBO
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[226][TOP]
>UniRef100_A6G2Q2 Methylenetetrahydrofolate reductase n=1 Tax=Plesiocystis pacifica
SIR-1 RepID=A6G2Q2_9DELT
Length = 310
Score = 88.2 bits (217), Expect = 3e-16
Identities = 40/99 (40%), Positives = 63/99 (63%)
Frame = +1
Query: 136 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
VFSFEFFPPK E G L ++++ P F +T+GAGGST + T+++ +++ +G+
Sbjct: 13 VFSFEFFPPKHEKGERVLWRSLEQLRTLEPDFVSVTYGAGGSTRERTVELVARIKTELGI 72
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
E M HLTC +++ +E + + + N+LALRGDPP
Sbjct: 73 EPMAHLTCVGSTRDELARVVERLLAADVHNILALRGDPP 111
[227][TOP]
>UniRef100_C1FN88 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
A2 str. Kyoto RepID=C1FN88_CLOBJ
Length = 295
Score = 87.8 bits (216), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIP 112
[228][TOP]
>UniRef100_B2UWX9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
E3 str. Alaska E43 RepID=B2UWX9_CLOBA
Length = 292
Score = 87.8 bits (216), Expect = 3e-16
Identities = 39/102 (38%), Positives = 65/102 (63%), Gaps = 1/102 (0%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADV-TLDIAKKMQNT 306
KVVFSFE FPPKT + + + +D + +P + +T+GAGGS + T++++ ++N
Sbjct: 11 KVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNTIELSSLIKNK 70
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
G+E + HLTC N+ + ++ L + N ++N+LALRGD P
Sbjct: 71 YGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVP 112
[229][TOP]
>UniRef100_B1L1W9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
A3 str. Loch Maree RepID=B1L1W9_CLOBM
Length = 295
Score = 87.8 bits (216), Expect = 3e-16
Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FP K + + E ++ + +P F +T+GAGGS D T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPSKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[230][TOP]
>UniRef100_A5I291 Methylenetetrahydrofolate reductase n=2 Tax=Clostridium botulinum A
RepID=A5I291_CLOBH
Length = 295
Score = 87.8 bits (216), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 276
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 277 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIP 112
[231][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 87.8 bits (216), Expect = 3e-16
Identities = 59/170 (34%), Positives = 81/170 (47%), Gaps = 39/170 (22%)
Frame = +1
Query: 40 SLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRM-VA 216
S SL A+ + + KI A D +SFEFFPPKT G+ NL R+ RM V
Sbjct: 9 SASLHGATASPSDPAHIATKIQAALTRDAP--FWSFEFFPPKTSQGLANLYNRIARMHVN 66
Query: 217 HSPSFCDITWGAGGSTADVTLDIAKKMQ---------------NTVGVETM--------- 324
PS+ +TWGAGG+T +L++A ++Q N +G T
Sbjct: 67 LEPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQTEINHIGSGTQQHIENVKGG 126
Query: 325 --------------MHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+HLTCTN+ +D L+T K G++N+LALRGDPP
Sbjct: 127 QEWEQERADPCDVCLHLTCTNVEKSSLDQTLDTAKRLGIKNILALRGDPP 176
[232][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 87.4 bits (215), Expect = 4e-16
Identities = 46/101 (45%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA +
Sbjct: 54 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 113
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC+ ++I L K GL+N+LALRGDP
Sbjct: 114 CGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDP 154
[233][TOP]
>UniRef100_Q3A3T2 Methylenetetrahydrofolate reductase n=1 Tax=Pelobacter carbinolicus
DSM 2380 RepID=Q3A3T2_PELCD
Length = 301
Score = 87.4 bits (215), Expect = 4e-16
Identities = 40/104 (38%), Positives = 62/104 (59%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 300
D + FSFEFFPPKT+ L E + ++ + P F +T+GAGGST + T D+ ++
Sbjct: 8 DRYETTFSFEFFPPKTDKAAERLYETIRQLESLHPHFTSVTYGAGGSTRERTHDLVMRIH 67
Query: 301 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ ++ + HLTC + P ++I L+ G+ N+LAL GDPP
Sbjct: 68 ESSSLDPIPHLTCVSSPEQEIHQILKRYAEAGISNILALAGDPP 111
[234][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 87.4 bits (215), Expect = 4e-16
Identities = 42/98 (42%), Positives = 59/98 (60%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 318
FSFEFFPPKT +G+ L D++ P F +T+GAGGST + T+D + G+
Sbjct: 11 FSFEFFPPKTPEGMEKLQVVRDKLAKRKPDFFSVTYGAGGSTRERTIDTVLTLHRQ-GIS 69
Query: 319 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T HL+C E I + L+ +SNG+Q ++ALRGD P
Sbjct: 70 TAPHLSCIGATKESIGELLDLYRSNGIQRIVALRGDLP 107
[235][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 87.4 bits (215), Expect = 4e-16
Identities = 42/99 (42%), Positives = 60/99 (60%)
Frame = +1
Query: 136 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 315
VFSFEFFPPKT++G L + + + P F +T+GAGGST TLD ++Q
Sbjct: 10 VFSFEFFPPKTDEGAEKLRKAREALAELKPKFFSVTYGAGGSTQARTLDTVLEIQRDARF 69
Query: 316 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
E HL+C E I + LE ++NG+++++ALRGD P
Sbjct: 70 EAAPHLSCIGSTREHIREILELYRNNGIRHIVALRGDMP 108
[236][TOP]
>UniRef100_B3QV58 Methylenetetrahydrofolate reductase n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QV58_CHLT3
Length = 294
Score = 87.4 bits (215), Expect = 4e-16
Identities = 39/103 (37%), Positives = 60/103 (58%)
Frame = +1
Query: 124 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 303
P+K FSFEF+PPK ++ L + ++ +P++ +T+GAGGST D T ++ ++
Sbjct: 9 PDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTHNLVVRISK 68
Query: 304 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ + HLTC +I LE NG+ N+LALRGDPP
Sbjct: 69 ETNIPVVSHLTCVGSSKSEIHTILERYAENGITNILALRGDPP 111
[237][TOP]
>UniRef100_C5EJM1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EJM1_9FIRM
Length = 292
Score = 87.4 bits (215), Expect = 4e-16
Identities = 46/102 (45%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNT 306
K SFE FPPKTED N +E+ + +A P+F +T+GAGG T+D T+ IA ++
Sbjct: 11 KPTLSFEVFPPKTEDN-YNTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTVGIASDIKE- 68
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
GV + HLTC + EK+ L+ +K++G++NVLALRGD P
Sbjct: 69 YGVTPLAHLTCVSSTREKVQGVLKELKAHGIENVLALRGDIP 110
[238][TOP]
>UniRef100_C1I310 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I310_9CLOT
Length = 297
Score = 87.4 bits (215), Expect = 4e-16
Identities = 40/105 (38%), Positives = 66/105 (62%), Gaps = 1/105 (0%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA-DVTLDIAKKM 297
D +VVFSFE FPPK E + + ++ + P F +T+GAGGS + ++T +I+ +
Sbjct: 8 DKKEVVFSFEIFPPKQESKIDTIYNTLEELKDLKPDFISVTYGAGGSLSKNMTCEISSIV 67
Query: 298 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+N +E + HLTC N +++ L+ +K +G++N+LALRGD P
Sbjct: 68 KNKYKIEPLAHLTCINSNKNQVNSILDNLKQSGIENILALRGDIP 112
[239][TOP]
>UniRef100_C0B744 Methylenetetrahydrofolate reductase n=1 Tax=Coprococcus comes ATCC
27758 RepID=C0B744_9FIRM
Length = 288
Score = 87.4 bits (215), Expect = 4e-16
Identities = 43/117 (36%), Positives = 71/117 (60%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 261
M++I+KI + V SFE FPPKT+ G ++L+ D + +PSF +T+GAGG
Sbjct: 1 MRIIDKIKA------DGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGG 54
Query: 262 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
T+ T+ IA ++N + + + HLTC + E++ + ++ G++N+LALRGD P
Sbjct: 55 TSKNTVKIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIP 111
[240][TOP]
>UniRef100_A8TTR8 Methylenetetrahydrofolate reductase n=1 Tax=alpha proteobacterium
BAL199 RepID=A8TTR8_9PROT
Length = 288
Score = 87.4 bits (215), Expect = 4e-16
Identities = 40/97 (41%), Positives = 59/97 (60%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFEFFPPK E G + L E +DR+ + P F +T+GAGGST + T I +++ G+E
Sbjct: 8 SFEFFPPKDEAGEIKLWETLDRLAPYGPRFVSVTYGAGGSTRERTSRIVTRIKRETGLEP 67
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
HLTC +++D+ G+++V+ALRGD P
Sbjct: 68 AAHLTCVGATCDEVDEVARGWWDAGIRHVVALRGDAP 104
[241][TOP]
>UniRef100_A1HTM2 Methylenetetrahydrofolate reductase n=1 Tax=Thermosinus
carboxydivorans Nor1 RepID=A1HTM2_9FIRM
Length = 285
Score = 87.4 bits (215), Expect = 4e-16
Identities = 42/111 (37%), Positives = 66/111 (59%)
Frame = +1
Query: 100 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTL 279
IH+ A + V SFE FPPK + + ++ + ++ + A P F +T+GA GST TL
Sbjct: 3 IHQLFAQ--KRPVVSFEIFPPKPDSPLESIFDCIEELQALKPDFISVTYGAAGSTRGRTL 60
Query: 280 DIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
++A+ +Q+ G+ + HLTC E I L ++G++N+LALRGDPP
Sbjct: 61 EVARHIQHDHGIPALGHLTCVGATAETIQAILHEFAAHGIENILALRGDPP 111
[242][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 87.4 bits (215), Expect = 4e-16
Identities = 48/133 (36%), Positives = 75/133 (56%), Gaps = 17/133 (12%)
Frame = +1
Query: 85 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 261
++ EK+++ S + V+S EFFPP+T G+ NL R+ RM A P + +TWG GGS
Sbjct: 11 RIDEKLND---STQDAYVWSLEFFPPRTALGLANLCARVARMSEALQPGWVHVTWGTGGS 67
Query: 262 TADVTLDIAKKMQNTV----------------GVETMMHLTCTNMPVEKIDDALETIKSN 393
T D ++++A ++Q V + +HLTCTN+ +D L+ +
Sbjct: 68 TRDASMELAARVQKGVYDPLEDYTNVKERRKGACDVCLHLTCTNVERAYLDATLDEARQI 127
Query: 394 GLQNVLALRGDPP 432
G++N+LALRGDPP
Sbjct: 128 GIRNILALRGDPP 140
[243][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 87.0 bits (214), Expect = 6e-16
Identities = 45/101 (44%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC + ++I L+ K GL+N++ALRGDP
Sbjct: 122 CGLETILHMTCCHQTRDEITGHLQKAKRLGLKNIMALRGDP 162
[244][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 87.0 bits (214), Expect = 6e-16
Identities = 45/101 (44%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +1
Query: 139 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 306
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 307 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 429
G+ET++H+TC + ++I L+ K GL+N++ALRGDP
Sbjct: 122 CGLETIVHMTCCHQTKDEITGHLQKAKRLGLKNIMALRGDP 162
[245][TOP]
>UniRef100_C8X270 5,10-methylenetetrahydrofolate reductase n=1 Tax=Desulfohalobium
retbaense DSM 5692 RepID=C8X270_9DELT
Length = 293
Score = 87.0 bits (214), Expect = 6e-16
Identities = 41/103 (39%), Positives = 61/103 (59%)
Frame = +1
Query: 124 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 303
P K S EFFPPK E E + ++ + P F +T+GAGGST D TL + +++
Sbjct: 9 PGKKFISLEFFPPKDEGNWPGFFEEVHQLASMDPLFVSVTYGAGGSTQDNTLRLVSRLKQ 68
Query: 304 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+G+E M HLTC + D + +++++ + NVLALRGDPP
Sbjct: 69 -MGLEPMAHLTCVGASAATLHDFMRSLQASDIDNVLALRGDPP 110
[246][TOP]
>UniRef100_B1C148 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium spiroforme
DSM 1552 RepID=B1C148_9FIRM
Length = 296
Score = 87.0 bits (214), Expect = 6e-16
Identities = 41/118 (34%), Positives = 72/118 (61%), Gaps = 1/118 (0%)
Frame = +1
Query: 82 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 258
MK+I+ +H+ + SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHK-------RPTLSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGG 53
Query: 259 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
ST T++IA K++N +E + HL+C + +++ ++ +K N ++N+L+LRGD P
Sbjct: 54 STTKNTVEIASKIKNDYNIEAVAHLSCIDASPKQLIKIIDALKENKIENILSLRGDYP 111
[247][TOP]
>UniRef100_B1BN89 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium perfringens
C str. JGS1495 RepID=B1BN89_CLOPE
Length = 292
Score = 87.0 bits (214), Expect = 6e-16
Identities = 40/103 (38%), Positives = 66/103 (64%), Gaps = 1/103 (0%)
Frame = +1
Query: 121 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS-TADVTLDIAKKM 297
D + VFSFE FPPK + N+ + ++ + P F +T+GAGG+ T++ T++++ +
Sbjct: 8 DKKEFVFSFEVFPPKESTSIKNIYKTLEEIQELKPDFISVTYGAGGNFTSNRTIELSSII 67
Query: 298 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 426
+N +ET+ HLTC ++I+ L +KS G++NVLALRGD
Sbjct: 68 KNKYNLETLAHLTCIGAKRKEIEQTLNILKSKGIENVLALRGD 110
[248][TOP]
>UniRef100_B0NAG8 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium scindens
ATCC 35704 RepID=B0NAG8_EUBSP
Length = 301
Score = 87.0 bits (214), Expect = 6e-16
Identities = 39/97 (40%), Positives = 63/97 (64%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFE FPPKT+ G + +++ A PSF +T+GAGG T+ T+ IA +++N +GV +
Sbjct: 27 SFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTVRIASQIKNDLGVTS 86
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ HLTC + +++ + +K G++N+LALRGD P
Sbjct: 87 LAHLTCVSSTKDEVHGVIGQLKEQGIENILALRGDIP 123
[249][TOP]
>UniRef100_B0G1G9 Methylenetetrahydrofolate reductase n=1 Tax=Dorea formicigenerans
ATCC 27755 RepID=B0G1G9_9FIRM
Length = 293
Score = 87.0 bits (214), Expect = 6e-16
Identities = 39/97 (40%), Positives = 62/97 (63%)
Frame = +1
Query: 142 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 321
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T+ IA +++ GV +
Sbjct: 17 SFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKNTVSIASHIKDDFGVTS 76
Query: 322 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
+ HLTC + E++ ++ +K + N+LALRGD P
Sbjct: 77 LAHLTCVSSTREEVHRVIDKLKEKNIDNILALRGDIP 113
[250][TOP]
>UniRef100_A8S2A1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium bolteae
ATCC BAA-613 RepID=A8S2A1_9CLOT
Length = 285
Score = 87.0 bits (214), Expect = 6e-16
Identities = 42/101 (41%), Positives = 60/101 (59%)
Frame = +1
Query: 130 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 309
K SFE FPPKTED ++ + + PSF +T+GAGG T++ T+ IA ++
Sbjct: 11 KPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSEYTVGIASAIKEEY 70
Query: 310 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 432
GV + HLTC + EK+ L ++ G++NVLALRGD P
Sbjct: 71 GVTPLAHLTCVSSTREKVHHVLGELRERGIENVLALRGDIP 111