[UP]
[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 296 bits (757), Expect = 7e-79
Identities = 142/166 (85%), Positives = 154/166 (92%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+IEKIH AA++DPN+VVFSFEFFPPKTEDGV NL ERMDRMV H+PSFCDITW AGG+
Sbjct: 1 MKIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGT 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA KMQN V VETMMHLTCTNMPVEKID AL TIKSNGLQNVLALRGDPPHGQ
Sbjct: 60 TADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQ 119
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
DKFVQVEGGFACARDLV+HIRAK+GDYFGIT+AGYPEAHPD I S+
Sbjct: 120 DKFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESD 165
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 294 bits (753), Expect = 2e-78
Identities = 144/178 (80%), Positives = 155/178 (87%), Gaps = 12/178 (6%)
Frame = +3
Query: 18 MKVIEKIHEAAA------------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP 161
MKVI+KI EAA S NKVVFSFEFFPPKTEDGV NL ERMDRMVAH+P
Sbjct: 1 MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP 60
Query: 162 SFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQN 341
SFCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QN
Sbjct: 61 SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 342 VLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
VLALRGDPPHGQDKFVQ++GGFACA DLVKHIR+K+GDYFGIT+AGYPEAHPDAIGS+
Sbjct: 121 VLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSD 178
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 288 bits (737), Expect = 1e-76
Identities = 140/175 (80%), Positives = 153/175 (87%), Gaps = 9/175 (5%)
Frame = +3
Query: 18 MKVIEKIHEAAA---------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFC 170
MKVI+KI AAA S NKVVFSFEFFPPKT+DGV NL ERMDRMV+H+PSFC
Sbjct: 1 MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC 60
Query: 171 DITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLA 350
DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QNVLA
Sbjct: 61 DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA 120
Query: 351 LRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
LRGDPPHGQDKFVQ++GG ACA DLVKHIR+K+GDYFGIT+AGYPEAHPD IGS+
Sbjct: 121 LRGDPPHGQDKFVQIQGGLACALDLVKHIRSKYGDYFGITVAGYPEAHPDVIGSD 175
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 284 bits (727), Expect = 2e-75
Identities = 135/163 (82%), Positives = 149/163 (91%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQ++GGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPD I
Sbjct: 120 DKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVI 162
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 284 bits (727), Expect = 2e-75
Identities = 135/163 (82%), Positives = 149/163 (91%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQ++GGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPD I
Sbjct: 120 DKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVI 162
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 284 bits (727), Expect = 2e-75
Identities = 135/163 (82%), Positives = 149/163 (91%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQ++GGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPD I
Sbjct: 120 DKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVI 162
[7][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 284 bits (726), Expect = 3e-75
Identities = 137/163 (84%), Positives = 148/163 (90%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI EAA + + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPDAI
Sbjct: 119 DKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAI 161
[8][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 283 bits (723), Expect = 6e-75
Identities = 137/165 (83%), Positives = 149/165 (90%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGS 512
DKFVQV GGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPDAI S
Sbjct: 119 DKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQS 163
[9][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 283 bits (723), Expect = 6e-75
Identities = 137/165 (83%), Positives = 149/165 (90%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGS 512
DKFVQV GGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPDAI S
Sbjct: 119 DKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQS 163
[10][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 282 bits (722), Expect = 8e-75
Identities = 137/163 (84%), Positives = 147/163 (90%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI EAA + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLV+HIRAK+GDYFGIT+AGYPEAHPDAI
Sbjct: 119 DKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAI 161
[11][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 280 bits (715), Expect = 5e-74
Identities = 139/179 (77%), Positives = 153/179 (85%), Gaps = 13/179 (7%)
Frame = +3
Query: 18 MKVIEKIHEA------------AASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS 158
MKVI+KI + A SD N KVVFSFEFFPPKTEDGV NL +RMDRMV+H+
Sbjct: 1 MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN 60
Query: 159 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 338
P+FCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+Q
Sbjct: 61 PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ 120
Query: 339 NVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
NVLALRGDPPHGQDKFVQVEGGFACA DLVKHIR+K+GDYFGIT+AGYPEAHPD I S+
Sbjct: 121 NVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIESD 179
[12][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 279 bits (713), Expect = 9e-74
Identities = 134/166 (80%), Positives = 145/166 (87%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVI+KI A D K FSFEFFPPKTEDGV NL ERMDRMVA+ P+FCDITWGAGGS
Sbjct: 1 MKVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TLDIA +MQN V VE+MMHLTCTNMPVEKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
DKFVQVEGGF CA DLV HIR+K+GDYFGIT+AGYPEAHPD IG N
Sbjct: 119 DKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGEN 164
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 276 bits (706), Expect = 6e-73
Identities = 133/163 (81%), Positives = 144/163 (88%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVIEKI A KVVFSFEFFPPKTE+GV NL +RMDRMV H PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TLDI+ KMQN + VE+MMHLTCTNMPVEKID AL TIK+NG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLVKHIR+K+GDYFGIT+AGYPEAHPD I
Sbjct: 119 DKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMI 161
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 270 bits (689), Expect = 5e-71
Identities = 125/163 (76%), Positives = 145/163 (88%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLV HIR+K+GDYFGIT+AGYPEAHPD I
Sbjct: 119 DKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVI 161
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 270 bits (689), Expect = 5e-71
Identities = 125/163 (76%), Positives = 145/163 (88%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLV HIR+K+GDYFGIT+AGYPEAHPD I
Sbjct: 119 DKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVI 161
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 270 bits (689), Expect = 5e-71
Identities = 125/163 (76%), Positives = 145/163 (88%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
DKFVQVEGGFACA DLV HIR+K+GDYFGIT+AGYPEAHPD I
Sbjct: 119 DKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVI 161
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 263 bits (672), Expect = 5e-69
Identities = 123/166 (74%), Positives = 143/166 (86%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T+ VTLDIA KMQN + VETMMHLTCTNM VE +D AL+++KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
DKFV +EGGF+CA DLV+HIRAK+GDYFGIT+AGYPEAHP+ IG +
Sbjct: 119 DKFVTIEGGFSCALDLVRHIRAKYGDYFGITVAGYPEAHPEVIGED 164
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 260 bits (664), Expect = 4e-68
Identities = 120/166 (72%), Positives = 142/166 (85%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T+ +TLDIA KMQN + VETMMHLTCTNM VE +D+AL+ +KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPHGQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
DKFV ++GGF+CA DLV+HI+ K+GDYFGIT+AGYPEAHPD IG +
Sbjct: 119 DKFVTIDGGFSCALDLVRHIKDKYGDYFGITVAGYPEAHPDVIGED 164
[19][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 244 bits (623), Expect = 2e-63
Identities = 113/137 (82%), Positives = 126/137 (91%)
Frame = +3
Query: 96 PKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTC 275
P+ +GV NL ERMDRMVAH P+FCDITWGAGGSTADVTLDIA +MQN V VETMMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 276 TNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGD 455
TNMPVEKID+AL+TIKSNG+QNVLALRGDPPHGQDKFVQV GGF+CA DLV+HI+AK+GD
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSCALDLVEHIKAKYGD 132
Query: 456 YFGITIAGYPEAHPDAI 506
YFGIT+AGYPEAHP+ I
Sbjct: 133 YFGITVAGYPEAHPEVI 149
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 203 bits (517), Expect = 5e-51
Identities = 101/163 (61%), Positives = 119/163 (73%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+I K+ E + FSFEFFPP+TE+GV NL ER+DRMVA+ P FCDITWGAGGS
Sbjct: 1 MKLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TADVTLDIA +MQN + VETMMHLTCTNMP EK++ AL +K G+QN+LALRGDPP
Sbjct: 59 TADVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPPK-- 116
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
V+V G C V ++HGDYFGI +AGYPEAHPD I
Sbjct: 117 ---VRV-GACVCVTSAVHQDESQHGDYFGICVAGYPEAHPDGI 155
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 195 bits (496), Expect = 1e-48
Identities = 95/163 (58%), Positives = 124/163 (76%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P F DITWGAGGS
Sbjct: 4 MKIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGS 61
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T+ +TL+IA+K QN G+ETMMHLTCTNMPV +I AL+ KS G++N+LALRGDPP G+
Sbjct: 62 TSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNILALRGDPPRGE 121
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
+ + ++EGGFA A DLV+ IR K+GDYF I++AGYPE H D +
Sbjct: 122 E-WKKIEGGFAYAADLVRFIREKYGDYFCISVAGYPEGHSDCV 163
[22][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 187 bits (476), Expect = 3e-46
Identities = 86/162 (53%), Positives = 117/162 (72%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 200
K+ +++ E +A V SFEFFPP+T+DGV +L+ R+ R P F D+TWGAGGST
Sbjct: 5 KISDRLQELSAKGEKFV--SFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+D+TLD+ +M G MHLTCTNMP EKID AL+ + G++N++ALRGDPP G++
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPPAGEE 122
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
+ VEGG++CA DLVKHIR +HGD+F I ++GYPE HP+AI
Sbjct: 123 AWEAVEGGYSCALDLVKHIRKEHGDFFSIAVSGYPEGHPNAI 164
[23][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 183 bits (464), Expect = 7e-45
Identities = 86/157 (54%), Positives = 116/157 (73%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ +KI ++A +D K+ +SFE+FPP+T G+ NLL+R++RM A P F DITW AGG
Sbjct: 1 MKITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL K +G +NVLALRGDPP G+
Sbjct: 59 TSDLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPE 488
D++ VEGGF DLV+HIR +GDYF I +AG+P+
Sbjct: 119 DEWEAVEGGFVHGIDLVRHIRRDYGDYFDIAVAGFPQ 155
[24][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 180 bits (457), Expect = 4e-44
Identities = 89/168 (52%), Positives = 116/168 (69%), Gaps = 2/168 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
M++ EK+ S K FSFE+F PKT GV NL +RMDRM + P F D+TW AGG
Sbjct: 1 MRISEKLQNHR-SKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGG 59
Query: 195 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
+ +T D+ + Q+ +G+ET MHLTCTNMPV +IDDALE+ + +G QN+LALRGDPP
Sbjct: 60 GVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPV 119
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
D + VEGGF A+DLV++IR K+GDYF I +AGYPE HP+ G +
Sbjct: 120 NSDSWQPVEGGFQYAKDLVRYIRDKYGDYFDIGVAGYPEGHPETAGDD 167
[25][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 174 bits (442), Expect = 2e-42
Identities = 82/162 (50%), Positives = 112/162 (69%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 200
K+ KI A A ++ +SFE+FPP+T G+ NL +R++RM P F DITW AGG T
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+D+T + K + +G+ET MHLTCTNMP EKID AL+ K G +N+LALRGDPP GQ
Sbjct: 76 SDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPPAGQS 135
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
++ GF A++LV++IR ++GDYF I +AG+PE HP+AI
Sbjct: 136 EWEPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAI 177
[26][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 174 bits (440), Expect = 4e-42
Identities = 85/164 (51%), Positives = 116/164 (70%), Gaps = 3/164 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ +K+ + P+K FSFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG 60
Query: 195 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP- 368
+ ++ ++ Q+ +G+ET MHLTCTNMP+ +ID+ALE ++G QN+LALRGDPP
Sbjct: 61 GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPPL 120
Query: 369 HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + + +EGGF A+DLVK+IRAK+GD+F I +AGYPE HP+
Sbjct: 121 NAPNGWQPIEGGFNYAKDLVKYIRAKYGDHFDIGVAGYPEGHPE 164
[27][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 172 bits (437), Expect = 9e-42
Identities = 84/163 (51%), Positives = 112/163 (68%), Gaps = 2/163 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 195 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + VEGGF A+DL+K+I++K+GD+F I +AGYPE HP+
Sbjct: 120 DAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPE 162
[28][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 172 bits (437), Expect = 9e-42
Identities = 84/163 (51%), Positives = 112/163 (68%), Gaps = 2/163 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 195 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + VEGGF A+DL+K+I++K+GD+F I +AGYPE HP+
Sbjct: 120 DAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPE 162
[29][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 172 bits (437), Expect = 9e-42
Identities = 84/163 (51%), Positives = 112/163 (68%), Gaps = 2/163 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 195 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + VEGGF A+DL+K+I++K+GD+F I +AGYPE HP+
Sbjct: 120 DAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPE 162
[30][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 172 bits (435), Expect = 2e-41
Identities = 83/162 (51%), Positives = 110/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M+V EK+ + A+ +K FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
+ ++ ++ Q+ +G+ET MHLTCTNMP + IDDAL+ +G QN+LALRGD P
Sbjct: 61 RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAPIT 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
++ EGGF A+DLV++IR K+GD+F I +AGYPE HP+
Sbjct: 121 SSEWKPCEGGFTYAKDLVRYIREKYGDHFDIGVAGYPEGHPE 162
[31][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 171 bits (434), Expect = 2e-41
Identities = 84/161 (52%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + EK+ + A++ +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ +G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ EGG A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EKWEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADD 159
[32][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 169 bits (429), Expect = 8e-41
Identities = 83/161 (51%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ +GGF A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EKWEATDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADD 159
[33][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 169 bits (428), Expect = 1e-40
Identities = 80/139 (57%), Positives = 101/139 (72%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q+ G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M +EK++DAL G N+LALRGDPP ++K+V +GGF ARDLVKH
Sbjct: 78 TCMHLTCTDMGLEKVNDALRKGYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKH 137
Query: 435 IRAKHGDYFGITIAGYPEA 491
IRA + D+F I +AGYPEA
Sbjct: 138 IRATYHDHFDIGVAGYPEA 156
[34][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 169 bits (428), Expect = 1e-40
Identities = 81/142 (57%), Positives = 100/142 (70%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+ +GGF ARDLVKH
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDKWTAADGGFQYARDLVKH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR+ +G++F I +AGYPE D
Sbjct: 138 IRSTYGNHFDIGVAGYPEGCDD 159
[35][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 169 bits (428), Expect = 1e-40
Identities = 83/161 (51%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 119 EKWEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDD 159
[36][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 169 bits (428), Expect = 1e-40
Identities = 83/161 (51%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 119 EKWEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDD 159
[37][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 169 bits (428), Expect = 1e-40
Identities = 82/161 (50%), Positives = 112/161 (69%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ +EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 119 EKWEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDD 159
[38][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 169 bits (428), Expect = 1e-40
Identities = 83/161 (51%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M V +K+ E AA+ + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHVGQKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ + Q G+ET MHLTCT+MP E++D ALE + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ EGGF A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EKWEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADD 159
[39][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 169 bits (428), Expect = 1e-40
Identities = 82/161 (50%), Positives = 112/161 (69%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ +EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 119 EKWEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDD 159
[40][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 169 bits (427), Expect = 1e-40
Identities = 81/161 (50%), Positives = 111/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ K+ +A A+D FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MKISHKLEKAHAADSTPT-FSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGR 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ Q+ +G+ET MHLTCT MP + +++AL++ G QN+LALRGDPP
Sbjct: 60 LSNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVES 119
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ V+GGF A+DLVK+I++K+GDYF I +A YPE P+
Sbjct: 120 EKWEAVDGGFRYAKDLVKYIKSKYGDYFDIGVAAYPEGTPE 160
[41][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 169 bits (427), Expect = 1e-40
Identities = 82/152 (53%), Positives = 105/152 (69%)
Frame = +3
Query: 45 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 224
A A + SFEFFPPKT GV NL +RMDRM PSF DITWGAGG A++T ++
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 225 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 404
Q+ G+ET MHLTCT+MP EK+D+AL++ G N+LALRGDPP ++ + Q EGG
Sbjct: 68 HVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPPREKESWEQTEGG 127
Query: 405 FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
F ARDLV++IR K+G++F I +AGYPE D
Sbjct: 128 FRYARDLVQYIREKYGNHFDIGVAGYPEGCED 159
[42][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 169 bits (427), Expect = 1e-40
Identities = 85/162 (52%), Positives = 110/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M + +K+ H AA P+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDKLAHSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGG 57
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 58 RLSDLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNILALRGDPPRE 117
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
++ + EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 118 KEAWAPTEGGFQYAKDLVKYIREKYGNHFDIGVAGYPEGCED 159
[43][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 168 bits (426), Expect = 2e-40
Identities = 81/142 (57%), Positives = 99/142 (69%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+ +GGF ARDLVKH
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKWEAADGGFQYARDLVKH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR +G++F I +AGYPE D
Sbjct: 138 IRNTYGNHFDIGVAGYPEGSDD 159
[44][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 168 bits (426), Expect = 2e-40
Identities = 79/141 (56%), Positives = 102/141 (72%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK+I
Sbjct: 79 CMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVKYI 138
Query: 438 RAKHGDYFGITIAGYPEAHPD 500
R K+G++F I +AGYPE D
Sbjct: 139 RVKYGNHFDIGVAGYPEGCED 159
[45][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 168 bits (425), Expect = 2e-40
Identities = 85/162 (52%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
++ + EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 118 KESWAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCED 159
[46][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 168 bits (425), Expect = 2e-40
Identities = 85/162 (52%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
++ + EGGF A+DLVK+IR K+G++F I +AGYPE D
Sbjct: 118 KESWAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCED 159
[47][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 168 bits (425), Expect = 2e-40
Identities = 79/141 (56%), Positives = 102/141 (72%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK+I
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVKYI 138
Query: 438 RAKHGDYFGITIAGYPEAHPD 500
R K+G++F I +AGYPE D
Sbjct: 139 RDKYGNHFDIGVAGYPEGCED 159
[48][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 168 bits (425), Expect = 2e-40
Identities = 79/141 (56%), Positives = 102/141 (72%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+ EGGF A+DLVK+I
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKWEATEGGFRYAKDLVKYI 138
Query: 438 RAKHGDYFGITIAGYPEAHPD 500
R K+G++F I +AGYPE D
Sbjct: 139 RDKYGNHFDIGVAGYPEGCED 159
[49][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 167 bits (424), Expect = 3e-40
Identities = 83/161 (51%), Positives = 106/161 (65%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + EK+ + A K SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIREKLAKNEAE--GKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MPVEK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + E GF A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EAWEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADD 159
[50][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 167 bits (424), Expect = 3e-40
Identities = 82/161 (50%), Positives = 109/161 (67%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + +GGF A+DLVK+IR+K+G++F I + GYPE D
Sbjct: 119 EAWEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADD 159
[51][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 167 bits (424), Expect = 3e-40
Identities = 83/161 (51%), Positives = 108/161 (67%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M V +K+++ A +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHVKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + EGG A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EAWEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADD 159
[52][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 167 bits (422), Expect = 5e-40
Identities = 81/161 (50%), Positives = 110/161 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ E S + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHIGQKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+++T ++ + Q G+ET MHLTCT+MP E++D ALE+ + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNILALRGDPPREQ 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ EGGF A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EKWEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADD 159
[53][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 165 bits (418), Expect = 1e-39
Identities = 84/162 (51%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
MK+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPPLD 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+K+I K+G++F I +AGYPE HP+
Sbjct: 121 GS---ESTGDFKYAKDLIKYIHKKYGNHFNIGVAGYPEGHPE 159
[54][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 165 bits (417), Expect = 2e-39
Identities = 81/161 (50%), Positives = 108/161 (67%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + EK+ + A+ K+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+D+T ++ Q+ G+ET MHLTCT+MP E++D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREK 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + +GGF A+DLVK+IR K+G++F I + GYPE D
Sbjct: 119 EVWEAADGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADD 159
[55][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 163 bits (412), Expect = 7e-39
Identities = 79/142 (55%), Positives = 97/142 (68%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+ EGGF A+DLV H
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEGGFQYAKDLVHH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR +G++F I +AGYPE D
Sbjct: 138 IRQTYGNHFDIGVAGYPEGCDD 159
[56][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 163 bits (412), Expect = 7e-39
Identities = 82/162 (50%), Positives = 110/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
MK+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNILALRGDPPLD 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+++IR K+GD+F I +A YPE HP+
Sbjct: 121 GS---ESTGDFKYAKDLIEYIRRKYGDHFNIGVAAYPEGHPE 159
[57][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 162 bits (411), Expect = 9e-39
Identities = 83/162 (51%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
MK+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPPLD 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+K+I K+ ++F I +AGYPE HP+
Sbjct: 121 GS---ESTGDFKYAKDLIKYIHEKYDNHFNIGVAGYPEGHPE 159
[58][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 162 bits (411), Expect = 9e-39
Identities = 81/162 (50%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPPLD 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+++IR K+GD+F I +A YPE HP+
Sbjct: 121 GS---ESTGDFKYAKDLIRYIRNKYGDHFNIGVAAYPEGHPE 159
[59][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 162 bits (411), Expect = 9e-39
Identities = 77/145 (53%), Positives = 100/145 (68%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 245
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 246 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 425
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 426 VKHIRAKHGDYFGITIAGYPEAHPD 500
VK+IR K+G++F I + GYPE D
Sbjct: 135 VKYIREKYGNHFDIGVGGYPEGADD 159
[60][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 162 bits (411), Expect = 9e-39
Identities = 81/163 (49%), Positives = 109/163 (66%), Gaps = 2/163 (1%)
Frame = +3
Query: 18 MKVIEKIHEA--AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAG 191
MK+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P F DITW AG
Sbjct: 1 MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG 60
Query: 192 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
G ++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNILALRGDPPL 120
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+ +IR K+G++F I +A YPE HP+
Sbjct: 121 DGS---ESTGDFKYAKDLILYIRKKYGNHFNIGVAAYPEGHPE 160
[61][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 162 bits (411), Expect = 9e-39
Identities = 77/145 (53%), Positives = 100/145 (68%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 245
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 246 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 425
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 426 VKHIRAKHGDYFGITIAGYPEAHPD 500
VK+IR K+G++F I + GYPE D
Sbjct: 135 VKYIREKYGNHFDIGVGGYPEGADD 159
[62][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 162 bits (410), Expect = 1e-38
Identities = 77/142 (54%), Positives = 99/142 (69%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M EK+++AL+ G N+LALRGDPP ++++ EGGF ARDLV H
Sbjct: 78 TCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKERWEAAEGGFQYARDLVAH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR +GD+F I +AGYPE D
Sbjct: 138 IRKLYGDHFDIGVAGYPEGCDD 159
[63][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 162 bits (409), Expect = 2e-38
Identities = 81/162 (50%), Positives = 109/162 (67%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 194
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPPLD 120
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+++IR K+GD+F I +A YPE HP+
Sbjct: 121 GS---ESTGDFKYAKDLIRYIRNKYGDHFNIGVAAYPEGHPE 159
[64][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 162 bits (409), Expect = 2e-38
Identities = 80/165 (48%), Positives = 107/165 (64%), Gaps = 4/165 (2%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M++ +K+ + A + FSFEFF PKT GV NL ERMDRM P F DITW AGG
Sbjct: 1 MRISQKL-QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGR 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG- 374
+ ++ D+ Q +G+ET MHLTCTNMPV +IDDAL+ G +N+LALRGDPP
Sbjct: 60 LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPPINS 119
Query: 375 ---QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
++++ E GF A+DLV +IR ++GD+F I +A YPE HP+
Sbjct: 120 LGEEEEWKPCENGFRYAKDLVSYIREQYGDHFDIGVAAYPEGHPE 164
[65][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 162 bits (409), Expect = 2e-38
Identities = 78/152 (51%), Positives = 99/152 (65%)
Frame = +3
Query: 45 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 224
A K FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 3 AETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMV 62
Query: 225 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 404
+ Q G+ET MHLTCT+M VEK++DAL G N+LALRGDPP ++K+ + G
Sbjct: 63 TQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEKWEAAQDG 122
Query: 405 FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
F A+DLV HIR +GD+F I +AGYPE D
Sbjct: 123 FNYAKDLVSHIRKTYGDHFDIGVAGYPEGCDD 154
[66][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 161 bits (408), Expect = 2e-38
Identities = 77/145 (53%), Positives = 99/145 (68%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 245
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 246 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 425
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++ + EGG A+DL
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEAWEATEGGLRYAKDL 134
Query: 426 VKHIRAKHGDYFGITIAGYPEAHPD 500
VK+IR K G++F I + GYPE D
Sbjct: 135 VKYIREKFGNHFDIGVGGYPEGADD 159
[67][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 161 bits (408), Expect = 2e-38
Identities = 79/161 (49%), Positives = 105/161 (65%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M + +K+ +A A K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG
Sbjct: 1 MHISQKLAQAKAE--GKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGR 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
+ +T ++ K Q G+ET MHLTCT+M K+D+AL +G N+LALRGDPP +
Sbjct: 59 HSKLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPPRER 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+K+ GGF A+DLVK+I+ K+G++F I +AGY E D
Sbjct: 119 EKWEATAGGFRYAKDLVKYIKEKYGNHFDIGVAGYSEGSDD 159
[68][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 161 bits (407), Expect = 3e-38
Identities = 82/168 (48%), Positives = 107/168 (63%), Gaps = 3/168 (1%)
Frame = +3
Query: 18 MKVIEKIHE---AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 188
M++ +K+ + AA + K FSFEFF PKT GV NL +RMDRM P F DITW A
Sbjct: 1 MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA 60
Query: 189 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 368
GG + T ++ Q +G+ET MHLTCTNM +D+ALE G +N+LALRGDPP
Sbjct: 61 GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENILALRGDPP 120
Query: 369 HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGS 512
Q + GGF A+DLV HIRA++GD+F + +AGYPE H +A G+
Sbjct: 121 L-QGTWEPCAGGFRYAKDLVAHIRARYGDHFDVGVAGYPEGHEEASGA 167
[69][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 161 bits (407), Expect = 3e-38
Identities = 77/142 (54%), Positives = 97/142 (68%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
MHLTCT+M EK++DAL G N+LALRGDPP Q+K+ EGGF ARDLV H
Sbjct: 78 ACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREQEKWEATEGGFQYARDLVGH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR +G++F I +AGYPE D
Sbjct: 138 IRKTYGNHFDIGVAGYPEGCDD 159
[70][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 160 bits (406), Expect = 4e-38
Identities = 78/142 (54%), Positives = 97/142 (68%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+ EGGF A+DLV +
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATEGGFQYAKDLVHY 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR +G++F I +AGYPE D
Sbjct: 138 IRQTYGNHFDIGVAGYPEGCDD 159
[71][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 160 bits (404), Expect = 6e-38
Identities = 81/164 (49%), Positives = 111/164 (67%), Gaps = 6/164 (3%)
Frame = +3
Query: 33 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPS-FCDITWGAGGSTADV 209
KI + D S E+FPP+T+ GV NL RMDRM+ ++ + + D+TWGAGGSTAD+
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTADL 71
Query: 210 TLDIAKKMQNTVGVETMMHLTCTNM-----PVEKIDDALETIKSNGLQNVLALRGDPPHG 374
+L++A T G + MHLTCTNM PV+ + DAL+ G++N++ALRGDPP G
Sbjct: 72 SLELALHAHKT-GHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPPEG 130
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
+ ++ EGGF+CA DLVK+IR GD FGI++AGYPE HP+ I
Sbjct: 131 EKEWTATEGGFSCALDLVKYIRKTFGDKFGISVAGYPEGHPNRI 174
[72][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 159 bits (403), Expect = 8e-38
Identities = 76/142 (53%), Positives = 98/142 (69%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T MHLTCT+M EK++DAL G N+LALRGDPP ++K+ EGGF ARDLV+H
Sbjct: 78 TCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEKWEAAEGGFRYARDLVQH 137
Query: 435 IRAKHGDYFGITIAGYPEAHPD 500
IR + ++F I +AGYPE D
Sbjct: 138 IRKSYHEHFDIGVAGYPEGCDD 159
[73][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 159 bits (402), Expect = 1e-37
Identities = 76/150 (50%), Positives = 98/150 (65%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A + K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG + +T ++ K
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKLTCEMVKV 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
Q G+ET MHLTCT+M K+DDAL +G N+LALRGDPP ++K+ GGF
Sbjct: 70 AQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREKWEATAGGFR 129
Query: 411 CARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
A+DLV +I+ K+G++F I +AGY E D
Sbjct: 130 YAKDLVVYIKEKYGNHFDIGVAGYSEGSDD 159
[74][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 158 bits (400), Expect = 2e-37
Identities = 78/155 (50%), Positives = 109/155 (70%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A P++ SFEFFPPKT+ G NLL R++RM+A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++ + F
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWIP-DCDFN 128
Query: 411 CARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
A DLVK+I+ ++GDYF I +AGYPE H D S+
Sbjct: 129 NAVDLVKYIKQQYGDYFCIGVAGYPEGHVDGSDSS 163
[75][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 158 bits (400), Expect = 2e-37
Identities = 83/164 (50%), Positives = 109/164 (66%), Gaps = 3/164 (1%)
Frame = +3
Query: 18 MKVIEKI---HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 188
MK+ EK+ H+AA S P FSFEFF PKT GV NL +RMDRM +P F DITW A
Sbjct: 1 MKISEKLDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNA 58
Query: 189 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 368
GG ++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL+ +G QN+LALRGDPP
Sbjct: 59 GGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPP 118
Query: 369 HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ G F A+DL+ +I K+ ++F I +AGYPE HP+
Sbjct: 119 LDGS---ESTGDFKYAKDLIAYIHKKYENHFNIGVAGYPEGHPE 159
[76][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 158 bits (399), Expect = 2e-37
Identities = 79/159 (49%), Positives = 109/159 (68%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M V++KI+ D SFEFFPPKT+ G NLL R+ RM+A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMLALNPLFITVTWGAGGS 57
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
+ + + F A DLVK+I+ +HGDYF I +AGYPE H
Sbjct: 118 EYWTP-DCDFYSAVDLVKYIKQQHGDYFCIGVAGYPEGH 155
[77][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 158 bits (399), Expect = 2e-37
Identities = 80/160 (50%), Positives = 110/160 (68%), Gaps = 1/160 (0%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ +K+ D +V +S+E+FPPKT GVVNL R++RM P+F D+TWGAGG
Sbjct: 1 MKITDKLQLPEYRD--RVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGG 58
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
S++D+T I K Q+ G++T MHLTCTNM ++ID+ALE G +N+LALRGDP
Sbjct: 59 SSSDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNILALRGDPVKH 118
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
+ ++ +EGGF A DLV+HIR K+GD F I +AGYPE +
Sbjct: 119 ESEWTALEGGFEYACDLVRHIRKKYGDEFCIGVAGYPEGY 158
[78][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 158 bits (399), Expect = 2e-37
Identities = 77/151 (50%), Positives = 106/151 (70%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 227
AA P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 228 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 407
QN +G+ T++HLTCTN E ID+AL+ K +G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNILALRGDPPRAEEYWTP-NCDF 127
Query: 408 ACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
A DLV++I+ +GDYF I +AGYPE H D
Sbjct: 128 NSAVDLVRYIKENYGDYFCIGVAGYPEGHVD 158
[79][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 157 bits (397), Expect = 4e-37
Identities = 78/155 (50%), Positives = 108/155 (69%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++ + F
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWIP-DCDFN 128
Query: 411 CARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
A DLVK+I+ ++GDYF I +AGYPE H D S+
Sbjct: 129 NAVDLVKYIKQQYGDYFCIGVAGYPEGHVDGSDSS 163
[80][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 157 bits (397), Expect = 4e-37
Identities = 78/151 (51%), Positives = 104/151 (68%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 227
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 228 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 407
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 408 ACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
A DLVK+IR K+GDYF I +A YPE H D
Sbjct: 128 NGAVDLVKYIREKYGDYFCIGVAAYPEGHVD 158
[81][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 157 bits (397), Expect = 4e-37
Identities = 79/165 (47%), Positives = 106/165 (64%), Gaps = 4/165 (2%)
Frame = +3
Query: 18 MKVIEKIHEA----AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWG 185
MK+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P F DITW
Sbjct: 1 MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN 60
Query: 186 AGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 365
AGG ++ +T ++ Q+T+G+ET MHLTCTNMPV ID+ALE +G QN+LALRGDP
Sbjct: 61 AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP 120
Query: 366 PHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
P + G F A+DL+ +IR ++GD+F I +A YPE HP+
Sbjct: 121 PLDGS---ESTGDFKYAKDLIVYIRKRYGDHFNIGVAAYPEGHPE 162
[82][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 157 bits (396), Expect = 5e-37
Identities = 79/159 (49%), Positives = 108/159 (67%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M V++KI+ D SFEFFPPKT+ G NLL R+ RM A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGS 57
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
+ + + F A DLVK+I+ +HGDYF I +AGYPE H
Sbjct: 118 EYWTP-DCDFYSAVDLVKYIKQQHGDYFCIGVAGYPEGH 155
[83][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 156 bits (395), Expect = 7e-37
Identities = 77/151 (50%), Positives = 104/151 (68%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 227
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 228 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 407
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 408 ACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ A DLVK+IR +GDYF I +A YPE H D
Sbjct: 128 SGAVDLVKYIRENYGDYFCIGVAAYPEGHVD 158
[84][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 156 bits (394), Expect = 9e-37
Identities = 77/147 (52%), Positives = 103/147 (70%)
Frame = +3
Query: 60 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 239
P++ SFEFFPPKT+ G NLL R++RM A +P F ITWGAGGST++ +LD+A Q
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTSEKSLDLAATCQK 72
Query: 240 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 419
VG+ T++HLTCTN E ID+AL K+NG++N+LALRGDPP ++ + F A
Sbjct: 73 EVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEEYWTP-NCDFNGAV 131
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPD 500
DLV++IR ++GDYF I +A YPE H D
Sbjct: 132 DLVRYIRQQYGDYFCIGVAAYPEGHVD 158
[85][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 155 bits (392), Expect = 1e-36
Identities = 77/151 (50%), Positives = 103/151 (68%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 227
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 228 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGF 407
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++ + F
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEYWTP-NCDF 127
Query: 408 ACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
A DLVK+IR +GDYF I +A YPE H D
Sbjct: 128 NGAVDLVKYIRENYGDYFCIGVAAYPEGHVD 158
[86][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 155 bits (392), Expect = 1e-36
Identities = 80/161 (49%), Positives = 109/161 (67%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M V+E+I A P++ SFEFFPPKT+ G NLL R+ RM +P F +TWGAGGS
Sbjct: 1 MSVVERIQ---ALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGS 57
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T++ +L++A Q +G+ T++HLTCTN IDDAL K+ G++N+LALRGDPP +
Sbjct: 58 TSEKSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPPRTR 117
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + E F A DLV++IRA++GDYF I +AGYPE H D
Sbjct: 118 EYWTP-ECSFRTAVDLVRYIRAQYGDYFCIGVAGYPEGHVD 157
[87][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 155 bits (392), Expect = 1e-36
Identities = 75/147 (51%), Positives = 103/147 (70%)
Frame = +3
Query: 60 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 239
P++ SFEFF PKT+ G NLL R++R++A +P F +TWGAGGST++ +LD+A QN
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTSEKSLDLAATCQN 72
Query: 240 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 419
+G+ T++HLTCTN E ID AL K+NG++N+LALRGDPP ++ + F A
Sbjct: 73 KIGINTVLHLTCTNTDKEIIDSALARAKANGIRNILALRGDPPRTEEYWTP-NCEFNNAV 131
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPD 500
DLVK+IR ++GDYF I +A YPE H D
Sbjct: 132 DLVKYIRQQYGDYFCIGVAAYPEGHVD 158
[88][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 153 bits (387), Expect = 6e-36
Identities = 75/161 (46%), Positives = 103/161 (63%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ EK+ +A + +SFEFFPP+T G+ NL +R++RM P F DITWGAGG
Sbjct: 1 MKITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGK 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
AD+T + + Q T+G+ET MHL CT MP EK++ AL KS+G QN+LALRGDP G
Sbjct: 59 NADLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGT 118
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ GGF A DLV++I + F + +AG+P+ HP+
Sbjct: 119 STWEPTPGGFMNAVDLVRYIHEHYPGDFCVAVAGFPQGHPE 159
[89][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 152 bits (385), Expect = 1e-35
Identities = 79/161 (49%), Positives = 103/161 (63%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
M I K+ A P++ FS EFFPPKT++G+ N R+ RM A P F ITWGAGGS
Sbjct: 1 MSTITKL--IAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGS 58
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +LDIA + Q+ +G++ +HLTCTNM ID ALE G+ N+LALRGDPP G+
Sbjct: 59 TAKKSLDIASECQS-MGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGE 117
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + F A DLVK+I+ KHG+ F + +AGYPE H D
Sbjct: 118 EYWQPASPEFQHAADLVKYIKKKHGNKFCVGVAGYPEGHVD 158
[90][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 149 bits (377), Expect = 8e-35
Identities = 82/164 (50%), Positives = 105/164 (64%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM IDDAL+ K+ G++N+LALRGDPP +
Sbjct: 61 ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNILALRGDPPRSDE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV+HIR KHGDYF I +A YPE H D
Sbjct: 121 YNLAGEDDSNKDFTYAIDLVRHIRRKHGDYFCIGVAAYPEGHAD 164
[91][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 149 bits (376), Expect = 1e-34
Identities = 72/158 (45%), Positives = 103/158 (65%), Gaps = 2/158 (1%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLE-RMDRMVAHSPSFCDITWGAGGSTADVTLDIA 224
AA D NK S+EF+PP++E N ++ ++ + SP F D+TWGAGG T++ T+ +
Sbjct: 10 AAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGRTSETTMRLC 69
Query: 225 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 401
K +QN MH+TCTNM + I + L+ K +G++N+LALRGDPP G D+F
Sbjct: 70 KDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG-DEFQSNPE 128
Query: 402 GFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
GF CARDLV++I A +GDYF +++AGYPE HP I +
Sbjct: 129 GFTCARDLVRYIHATYGDYFCVSVAGYPEGHPSRIAED 166
[92][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 149 bits (375), Expect = 1e-34
Identities = 73/147 (49%), Positives = 97/147 (65%)
Frame = +3
Query: 54 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 233
S+ N+ S EFFPPKT+ G NLL R++RM A P F +TWGAGGSTA+ TL++A
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEKTLELAALA 68
Query: 234 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFAC 413
Q + + MHLTCTNM +D AL K G++N+LALRGD P D+ V+GGF
Sbjct: 69 QRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNILALRGDMPLAADEEEHVDGGFLY 128
Query: 414 ARDLVKHIRAKHGDYFGITIAGYPEAH 494
A DLV++I+ ++GDYF I +A YP+ H
Sbjct: 129 AIDLVRYIKMQYGDYFCIGVAAYPDGH 155
[93][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 148 bits (373), Expect = 2e-34
Identities = 76/158 (48%), Positives = 105/158 (66%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 200
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P F +TWGAGG+T
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+ TLD+A Q + + T +HLTCTN + ID+AL+ NG++N+LALRGDPP +
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPPR-EA 117
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
+ V V+ F A DLV++IR ++GDYF I +A YPE H
Sbjct: 118 QEVAVDQDFKYAIDLVRYIRGQYGDYFCIGVAAYPEGH 155
[94][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 147 bits (370), Expect = 5e-34
Identities = 81/167 (48%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR KHGDYF + +A YPE HP
Sbjct: 120 EYNMHGED---DSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHP 163
[95][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 147 bits (370), Expect = 5e-34
Identities = 81/167 (48%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 51 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 107
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 108 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 167
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR KHGDYF + +A YPE HP
Sbjct: 168 EYNMHGED---DSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHP 211
[96][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 146 bits (368), Expect = 9e-34
Identities = 82/165 (49%), Positives = 109/165 (66%), Gaps = 5/165 (3%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI EA D + FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KISDKI-EALPKDAH--YFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q +G+ T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSE 119
Query: 378 DKFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + E F+ A DLV++IR K+GDYF I +AGYPE H D
Sbjct: 120 EYNIDGEDDSNKDFSHAVDLVRYIRKKYGDYFCIGVAGYPEGHAD 164
[97][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 145 bits (367), Expect = 1e-33
Identities = 81/166 (48%), Positives = 104/166 (62%), Gaps = 9/166 (5%)
Frame = +3
Query: 27 IEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP---- 368
A +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 61 AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE 120
Query: 369 ---HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR K+GDYF + +A YPE HP
Sbjct: 121 YNMHGED---DSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHP 163
[98][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 145 bits (366), Expect = 2e-33
Identities = 82/167 (49%), Positives = 106/167 (63%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 86
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 87 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 146
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR K+GDYF + +A YPE HP
Sbjct: 147 EYNMHGED---DSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHP 190
[99][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 144 bits (364), Expect = 3e-33
Identities = 73/141 (51%), Positives = 94/141 (66%), Gaps = 2/141 (1%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S EFFPPKTE G NLLERM RM A P F +TWGAGG+TA+ TL++A +N++ +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD--KFVQVEGGFACARDLVK 431
+HLTCTNM ID+ALE K G++N+LALRGDPP G+D F A DLV+
Sbjct: 77 CIHLTCTNMSRGIIDEALEACKKIGIRNILALRGDPPIGEDWNDMESELNEFKYAIDLVR 136
Query: 432 HIRAKHGDYFGITIAGYPEAH 494
+I+ +GDYF + +A YPE H
Sbjct: 137 YIKQNYGDYFCVGVAAYPEGH 157
[100][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 144 bits (363), Expect = 3e-33
Identities = 80/170 (47%), Positives = 106/170 (62%), Gaps = 8/170 (4%)
Frame = +3
Query: 15 KMKVIEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGA 188
K ++KI + A+ P + FS EFFPPKT G NL R+DRM A P F ++TWGA
Sbjct: 16 KSHAMDKITDKIAALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRMARALRPLFVNVTWGA 75
Query: 189 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 368
GGSTA +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP
Sbjct: 76 GGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAKALGIRNILALRGDPP 135
Query: 369 H------GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + E F+ A DLV++IR HGDYF I +A YPE H D
Sbjct: 136 RRAEYRDANEPEPEEEEEFSWAVDLVRYIRKTHGDYFCIGVAAYPEGHAD 185
[101][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 144 bits (363), Expect = 3e-33
Identities = 81/167 (48%), Positives = 104/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR +HGDYF I +A YPE HP
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVRYIRQQHGDYFCIGVAAYPEGHP 163
[102][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 144 bits (363), Expect = 3e-33
Identities = 81/170 (47%), Positives = 106/170 (62%), Gaps = 10/170 (5%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSD 119
Query: 378 D-KFVQVEGG--------FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + V + G F A DLV++IR ++GDYF + +A YPE H D
Sbjct: 120 EYRAVDEKNGDLPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHAD 169
[103][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 144 bits (362), Expect = 4e-33
Identities = 79/164 (48%), Positives = 104/164 (63%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLVK+IR HGDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSD 164
[104][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 144 bits (362), Expect = 4e-33
Identities = 79/164 (48%), Positives = 104/164 (63%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLVK+IR HGDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSD 164
[105][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 144 bits (362), Expect = 4e-33
Identities = 80/170 (47%), Positives = 107/170 (62%), Gaps = 10/170 (5%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP +
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSE 119
Query: 378 D-KFVQVEGG--------FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + + + G F A DLV++IR ++GDYF + +A YPE H D
Sbjct: 120 EYRALDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHAD 169
[106][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 144 bits (362), Expect = 4e-33
Identities = 79/164 (48%), Positives = 104/164 (63%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLVK+IR HGDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSD 164
[107][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 143 bits (361), Expect = 6e-33
Identities = 80/167 (47%), Positives = 104/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ EKI AA P+ FS EFFPPKT G NL R++RM A P F +TWGAGGS
Sbjct: 4 KITEKI---AALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS 60
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T++HLTCTNM + +D AL+ K G++N+LALRGDPP
Sbjct: 61 TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE 120
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR HGDYF + +A YPE HP
Sbjct: 121 EYNMHGED---DSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHP 164
[108][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 143 bits (360), Expect = 8e-33
Identities = 71/148 (47%), Positives = 102/148 (68%), Gaps = 6/148 (4%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVA---HSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
++EFFPP T+ G VNLL+R+ R+ + +P +TWGAGGSTA+ +L++A+++ + +G
Sbjct: 17 NYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGSTAEKSLELAQQVVD-MG 75
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV---QVEGGFACAR 419
VE ++HLTCTNMP +K+D AL K G+ N+LALRGDPP ++ + F A
Sbjct: 76 VEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEYAINPTSTPDFFKHAD 135
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDA 503
DLV++IR HGDYF I +AGYP HPD+
Sbjct: 136 DLVRYIRQTHGDYFCIGVAGYPNPHPDS 163
[109][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 143 bits (360), Expect = 8e-33
Identities = 81/167 (48%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR +GDYF + +A YPE HP
Sbjct: 120 EYNTHGED---DSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHP 163
[110][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 143 bits (360), Expect = 8e-33
Identities = 79/164 (48%), Positives = 104/164 (63%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + A+ P N FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLVK+IR HGD+F I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSD 164
[111][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 143 bits (360), Expect = 8e-33
Identities = 72/145 (49%), Positives = 95/145 (65%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ EK+ A + FSFEFF PKT GV NL +RMDRM SP F DITW AGG
Sbjct: 1 MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR 60
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
++++T ++ Q +G+ET MHLTCTNM +E ID+AL++ +G QN+LALRGDPP
Sbjct: 61 SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPPLDG 120
Query: 378 DKFVQVEGGFACARDLVKHIRAKHG 452
+ G F A+DL+KHI+ K+G
Sbjct: 121 S---ESTGCFRYAKDLIKHIKEKYG 142
[112][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 143 bits (360), Expect = 8e-33
Identities = 81/167 (48%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR +GDYF + +A YPE HP
Sbjct: 120 EYNTHGED---DSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHP 163
[113][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 143 bits (360), Expect = 8e-33
Identities = 81/167 (48%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR K+GDYF + +A YPE HP
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHP 163
[114][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 142 bits (359), Expect = 1e-32
Identities = 77/164 (46%), Positives = 104/164 (63%), Gaps = 5/164 (3%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ EKI AA P FS EFFPPKT+ G VNL R++RM P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPPRSE 119
Query: 378 DKFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
+ + + F A DLV++IR +GDYF + +A YPE HP
Sbjct: 120 EYNMDGDDDSNKDFTWAIDLVRYIRRTYGDYFCVGVAAYPEGHP 163
[115][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 142 bits (359), Expect = 1e-32
Identities = 67/164 (40%), Positives = 108/164 (65%), Gaps = 2/164 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P +TWGAGGS
Sbjct: 1 MKLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGS 57
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D +L++A Q ++T++HLTCTNM +D+ L+ ++ G+QN+LALRGDPP G+
Sbjct: 58 TKDRSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNILALRGDPPRGE 117
Query: 378 DKFVQVEGGFACARDLVKHIRA--KHGDYFGITIAGYPEAHPDA 503
++++ + F A DLV +I A ++ F + +A YP+ H ++
Sbjct: 118 EEWIPSDPRFTHAVDLVSYISASPEYSSDFCVGVAAYPDGHTES 161
[116][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 142 bits (359), Expect = 1e-32
Identities = 80/167 (47%), Positives = 105/167 (62%), Gaps = 8/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP--- 368
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 369 ----HGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
HG+D F A DLV++IR ++GDYF I +A YPE HP
Sbjct: 120 EYNMHGED---DSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHP 163
[117][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 142 bits (358), Expect = 1e-32
Identities = 78/164 (47%), Positives = 106/164 (64%), Gaps = 5/164 (3%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSE 119
Query: 378 DKFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
+ + + F A DLV++IR +G+YF I +A YPE HP
Sbjct: 120 EYNMDGDDDSNKDFTWAIDLVRYIRKIYGNYFCIGVAAYPEGHP 163
[118][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 142 bits (357), Expect = 2e-32
Identities = 70/156 (44%), Positives = 97/156 (62%)
Frame = +3
Query: 33 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVT 212
KIH A P K +FSFEFFPPKTE+G L + + P+F +T+GAGGS T
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 213 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQ 392
++ ++++ VG+E M HLTC E+I + LE ++ G +N++A+RGDPP GQ +F
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAVRGDPPKGQREFRP 119
Query: 393 VEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
VEGGF A +LV IR ++GD F I YPE HP+
Sbjct: 120 VEGGFRYASELVAFIRERYGDAFSIAGGAYPEGHPE 155
[119][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 142 bits (357), Expect = 2e-32
Identities = 69/158 (43%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERM-DRMVAHSPSFCDITWGAGGSTADVTLDIA 224
AA D +K S+E +PP++E ++++ + + SP F D+TWGAGG T+D T+ +
Sbjct: 10 AAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGRTSDTTMRLC 69
Query: 225 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 401
K +Q+ MH+TCTN P I++AL+ K++G++N+LALRGDPP G++ F
Sbjct: 70 KDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRGEE-FRADPD 128
Query: 402 GFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
GFACARDLV++I +GDYF +++AGYPE HP I +
Sbjct: 129 GFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIAED 166
[120][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 142 bits (357), Expect = 2e-32
Identities = 80/167 (47%), Positives = 103/167 (61%), Gaps = 7/167 (4%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
K+ +KI AA N FS EFFPPKT G NL +R+DRM A P F ++TWGAGGS
Sbjct: 3 KITDKI---AALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGS 59
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
TA +L++A+ Q +G+ T +HLTCTNM +D AL+ K G++N+LALRGDPP
Sbjct: 60 TAFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKA 119
Query: 378 DKFVQVE------GGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ V+ F A DLVK+IR HGDYF I +A YPE H +
Sbjct: 120 EYQDAVDEESDDGEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAE 166
[121][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 141 bits (356), Expect = 2e-32
Identities = 78/164 (47%), Positives = 102/164 (62%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
Query: 381 KFVQVEGG----FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR KH DYF I +A YPE H D
Sbjct: 121 YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSD 164
[122][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 141 bits (356), Expect = 2e-32
Identities = 78/164 (47%), Positives = 102/164 (62%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
Query: 381 KFVQVEGG----FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR KH DYF I +A YPE H D
Sbjct: 121 YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSD 164
[123][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 141 bits (356), Expect = 2e-32
Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 206
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 207 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 380
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
E F A DLV++I+ +GD F + +A YPE H
Sbjct: 119 DSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156
[124][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 141 bits (355), Expect = 3e-32
Identities = 78/166 (46%), Positives = 109/166 (65%), Gaps = 8/166 (4%)
Frame = +3
Query: 27 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
++KI + A+ P + FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+ +L++A+ Q VG+ T +HLTCTNM + ID+AL K+ G++N+LALRGDPP ++
Sbjct: 61 SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE 120
Query: 381 ----KFVQVEGG--FACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + +GG F A DLV++IR HGDYF I +A YPE H +
Sbjct: 121 YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAE 166
[125][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 141 bits (355), Expect = 3e-32
Identities = 71/158 (44%), Positives = 103/158 (65%), Gaps = 2/158 (1%)
Frame = +3
Query: 48 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIA 224
AA D +K S+E +PP++E ++++ + H SP F D+TWGAGG T+ T+ +
Sbjct: 10 AAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGRTSGTTMRLC 69
Query: 225 KKMQNT-VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEG 401
K +Q+ MH+TCTN P I + LE K++G++N+LALRGDPP G++ V +G
Sbjct: 70 KDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNILALRGDPPSGEEFQVDPDG 129
Query: 402 GFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSN 515
FACARDLV++IR +GDYF +++AGYPE HP I N
Sbjct: 130 -FACARDLVRYIRDTYGDYFCVSVAGYPEGHPSRIAEN 166
[126][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 141 bits (355), Expect = 3e-32
Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 206
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 207 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 380
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
E F A DLV++I+ +GD F + +A YPE H
Sbjct: 119 DSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156
[127][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 141 bits (355), Expect = 3e-32
Identities = 74/141 (52%), Positives = 90/141 (63%), Gaps = 2/141 (1%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S EFFPPKTE G NLLERM+RM A P F +TWGAGGSTA+ TL++A Q + +
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKTLELASLAQKNLNLPI 75
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD--KFVQVEGGFACARDLVK 431
MHLTCTNM IDDAL K+ G+ N+LALRGDPP GQD + F A DLV+
Sbjct: 76 CMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPPIGQDWSDLEASQSEFKHAVDLVR 135
Query: 432 HIRAKHGDYFGITIAGYPEAH 494
+I + + F I +A YPE H
Sbjct: 136 YINYRFPNEFCIGVAAYPEGH 156
[128][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 141 bits (355), Expect = 3e-32
Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 206
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 207 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 380
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
E F A DLV++I+ +GD F + +A YPE H
Sbjct: 119 DSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156
[129][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 141 bits (355), Expect = 3e-32
Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 206
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 207 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 380
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
E F A DLV++I+ +GD F + +A YPE H
Sbjct: 119 DSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156
[130][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 141 bits (355), Expect = 3e-32
Identities = 64/115 (55%), Positives = 83/115 (72%)
Frame = +3
Query: 144 MVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIK 323
M A P F DITW AGG T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL+ K
Sbjct: 1 MRALGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAK 60
Query: 324 SNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPE 488
+G +N+LALRGDPP G+D++ VEGGF DLV+HIR +GDYF I + G+P+
Sbjct: 61 EHGCRNILALRGDPPMGKDEWEAVEGGFVHGIDLVRHIRKHYGDYFDIAVPGFPQ 115
[131][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 141 bits (355), Expect = 3e-32
Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 206
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 207 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD-- 380
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWL 118
Query: 381 KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
E F A DLV++I+ +GD F + +A YPE H
Sbjct: 119 DSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156
[132][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 140 bits (354), Expect = 4e-32
Identities = 75/152 (49%), Positives = 97/152 (63%), Gaps = 5/152 (3%)
Frame = +3
Query: 54 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 233
SD + + S EFFPPKTE G NLLERM+RM A P F +TWGAGGST++ TL++A+
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKTLELAQIA 67
Query: 234 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP---HGQDKFVQVEGG 404
Q + V MHLTCTNM I +AL+ +S G++N+LALRGD P DK + G
Sbjct: 68 QRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAPIEDQWDDKTINSSEG 127
Query: 405 --FACARDLVKHIRAKHGDYFGITIAGYPEAH 494
F A DLV++I+ +GD F I +A YPE H
Sbjct: 128 PEFRYAVDLVRYIKENYGDEFCIGVAAYPEGH 159
[133][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 140 bits (354), Expect = 4e-32
Identities = 74/147 (50%), Positives = 95/147 (64%), Gaps = 2/147 (1%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGGSTADVTLDIAKKMQNT 242
KV +S+EFFPPKT GV NL R+DRM P F D+TWGAGG+++++T I +Q
Sbjct: 15 KVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTD 74
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
V+T MHLTCTNM E ID AL+ G +N+LALRGDP D + + E GF A D
Sbjct: 75 FEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTD-WTEGESGFRYASD 133
Query: 423 LVKHIRAKHGDYFGITIAGYPEAH-PD 500
LV++IR + D F I +AGYPE + PD
Sbjct: 134 LVRYIRTHYNDEFCIGVAGYPEGYSPD 160
[134][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 140 bits (352), Expect = 6e-32
Identities = 76/166 (45%), Positives = 102/166 (61%), Gaps = 8/166 (4%)
Frame = +3
Query: 27 IEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGST 200
+EKI + AA P+ FS EFFPPKT G NL +R++RM P F ++TWGAGGST
Sbjct: 1 MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG-- 374
A +L++A+ Q +G+ T +HLTCTNM +D LE K G++N+LALRGDPP
Sbjct: 61 AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE 120
Query: 375 ----QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
D + F+ A DLV++I+ HGDYF I +A YPE H +
Sbjct: 121 YHDENDPEPTDDEEFSWAADLVRYIKKTHGDYFCIGVAAYPEGHAE 166
[135][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 140 bits (352), Expect = 6e-32
Identities = 75/149 (50%), Positives = 99/149 (66%), Gaps = 7/149 (4%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 251
FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST+ +L++A+ Q +G+
Sbjct: 18 FSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGSTSQKSLELAELCQRELGL 77
Query: 252 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD----KFVQVEGG--FAC 413
T +HLTCTNM + ID ALE K+ G++N+LALRGDPP ++ + +GG F
Sbjct: 78 TTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREEYRDPDDSEDDGGQDFNW 137
Query: 414 ARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
A DLVK+IR HGDYF I +A YPE H +
Sbjct: 138 AADLVKYIRKTHGDYFCIGVAAYPEGHAE 166
[136][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 140 bits (352), Expect = 6e-32
Identities = 75/164 (45%), Positives = 103/164 (62%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F ++TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR +GDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSD 164
[137][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 139 bits (351), Expect = 8e-32
Identities = 75/148 (50%), Positives = 96/148 (64%), Gaps = 5/148 (3%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 251
+SFEFFPPKTE G+ NLL R+DRM P F ITWG+ GST TL +A Q V
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV 60
Query: 252 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQ--VEGGFACAR-- 419
+ ++HL+CT + E+I L KS+G+ N+LALRGDPP G+ + + V GG C R
Sbjct: 61 DVLLHLSCTGLTREQIGHVLAMAKSSGVHNILALRGDPPQGKRAWKEGDVSGG-ECDRAI 119
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDA 503
DLVK IR HG+YFGI +AG+PE HP +
Sbjct: 120 DLVKLIRRLHGNYFGIGVAGHPEGHPSS 147
[138][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 139 bits (350), Expect = 1e-31
Identities = 75/164 (45%), Positives = 102/164 (62%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR +GDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSD 164
[139][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 139 bits (350), Expect = 1e-31
Identities = 81/169 (47%), Positives = 105/169 (62%), Gaps = 11/169 (6%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+EKI + S P+ FS EFFPPKT G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
A +L++A+ Q +G+ T +HLTCTNM + IDDALE K G++N+LALRGD P ++
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE 120
Query: 381 KFVQVEG---------GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ EG F A DLVK+IR ++GDYF I +A YPE H D
Sbjct: 121 --YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSD 167
[140][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 139 bits (349), Expect = 1e-31
Identities = 73/147 (49%), Positives = 93/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 125 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 182
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + GDYF I +AGYP+ HPDA
Sbjct: 183 LVKHIRNEFGDYFDICVAGYPKGHPDA 209
[141][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 139 bits (349), Expect = 1e-31
Identities = 73/147 (49%), Positives = 93/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 217
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + GDYF I +AGYP+ HPDA
Sbjct: 218 LVKHIRNEFGDYFDICVAGYPKGHPDA 244
[142][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 138 bits (348), Expect = 2e-31
Identities = 75/164 (45%), Positives = 102/164 (62%), Gaps = 6/164 (3%)
Frame = +3
Query: 27 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 200
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST 60
Query: 201 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 380
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
Query: 381 KFVQVEG----GFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR +GDYF I +A YPE H D
Sbjct: 121 YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSD 164
[143][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 138 bits (347), Expect = 2e-31
Identities = 75/147 (51%), Positives = 95/147 (64%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E+++HLTC N EKI D L K GL+N++ALRGDP G+D +V+ +GGF A D
Sbjct: 120 CGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPV-GED-WVEEDGGFNFATD 177
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HP+A
Sbjct: 178 LVKHIRHEFDDYFDICVAGYPTGHPEA 204
[144][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 138 bits (347), Expect = 2e-31
Identities = 74/164 (45%), Positives = 102/164 (62%), Gaps = 2/164 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAG 191
MK+++ I + PN +SFE+FPPKT G+ NL R+ RM + P F +TWG
Sbjct: 1 MKIVDLIDKI----PNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTA 56
Query: 192 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
GSTA+V++ +AK ++ + +HLTCTN+ ID ALET K G++N+LALRGDPP
Sbjct: 57 GSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPPL 116
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
D + F A DLV++IR K+GDYF I +A YPE H D+
Sbjct: 117 NSDHWEGKVSEFEHAVDLVRYIREKYGDYFCIGVAAYPEGHVDS 160
[145][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 137 bits (346), Expect = 3e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + + + IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 143 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 200
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF I +AGYP+ HP+A
Sbjct: 201 LVKHIRSEFGDYFDICVAGYPKGHPEA 227
[146][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 137 bits (346), Expect = 3e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + + + IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 161 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 218
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF I +AGYP+ HP+A
Sbjct: 219 LVKHIRSEFGDYFDICVAGYPKGHPEA 245
[147][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 137 bits (346), Expect = 3e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + + + IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 120 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 177
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF I +AGYP+ HP+A
Sbjct: 178 LVKHIRSEFGDYFDICVAGYPKGHPEA 204
[148][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 137 bits (346), Expect = 3e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + + + IA N
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 149
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 150 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 207
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF I +AGYP+ HP+A
Sbjct: 208 LVKHIRSEFGDYFDICVAGYPKGHPEA 234
[149][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 137 bits (344), Expect = 5e-31
Identities = 71/147 (48%), Positives = 95/147 (64%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + + + IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N+LALRGDP D++ + EGGF+ A D
Sbjct: 119 CGLETVLHMTCCRQSREEITGYLHKAKRLGLKNILALRGDPVG--DQWEEEEGGFSYAAD 176
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF + +AGYP+ HPD+
Sbjct: 177 LVKHIRSEFGDYFDVCVAGYPKGHPDS 203
[150][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 137 bits (344), Expect = 5e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 143 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 200
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF + +AGYP+ HP+A
Sbjct: 201 LVKHIRSEFGDYFDLCVAGYPKGHPEA 227
[151][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 137 bits (344), Expect = 5e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 161 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 218
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF + +AGYP+ HP+A
Sbjct: 219 LVKHIRSEFGDYFDLCVAGYPKGHPEA 245
[152][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 137 bits (344), Expect = 5e-31
Identities = 71/147 (48%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC +E+I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 120 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVD 177
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF + +AGYP+ HP+A
Sbjct: 178 LVKHIRSEFGDYFDLCVAGYPKGHPEA 204
[153][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 136 bits (343), Expect = 7e-31
Identities = 72/147 (48%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 217
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HPDA
Sbjct: 218 LVKHIRTEFADYFDICVAGYPRGHPDA 244
[154][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 136 bits (343), Expect = 7e-31
Identities = 72/147 (48%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 217
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HPDA
Sbjct: 218 LVKHIRTEFADYFDICVAGYPRGHPDA 244
[155][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 136 bits (343), Expect = 7e-31
Identities = 72/147 (48%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 217
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HPDA
Sbjct: 218 LVKHIRTEFADYFDICVAGYPRGHPDA 244
[156][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 136 bits (343), Expect = 7e-31
Identities = 66/133 (49%), Positives = 91/133 (68%), Gaps = 2/133 (1%)
Frame = +3
Query: 111 GVVNLLERMDRMVAHSPSFCDITWGAGG--STADVTLDIAKKMQNTVGVETMMHLTCTNM 284
GV NL ER+DRM P + D+TWGAGG S+++ T +I + G++ MMHLTCT+
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTHQ 61
Query: 285 PVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFG 464
VE+ID+ L+ K G++N+LALRGD P ++ +GGF+ A DLV+HIR K+GDYF
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVRHIRGKYGDYFC 121
Query: 465 ITIAGYPEAHPDA 503
I +AGYPE H +A
Sbjct: 122 IAVAGYPEGHLEA 134
[157][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 136 bits (343), Expect = 7e-31
Identities = 70/163 (42%), Positives = 96/163 (58%), Gaps = 4/163 (2%)
Frame = +3
Query: 24 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW----GAG 191
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P F D+TW +G
Sbjct: 26 IIQKIRKRINSGDK--FYSLEFFPPRTDSGGVNLIARFDRLAIGNPLFIDVTWHPKGNSG 83
Query: 192 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
G +L IA N G+++M+H+TC N E ID L K GL+N+LALRGD
Sbjct: 84 GDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNILALRGDVSD 143
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
D+ V+ A DLVKHIR + G+YFGI +AGYP+ HP+
Sbjct: 144 SIDESVRHTKELKYASDLVKHIRKEFGNYFGIAVAGYPDGHPE 186
[158][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 136 bits (343), Expect = 7e-31
Identities = 78/172 (45%), Positives = 104/172 (60%), Gaps = 10/172 (5%)
Frame = +3
Query: 15 KMKVIEKIHEAAASDPNKVVF-SFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGA 188
K ++KI + A+ P + + S EFFPPKT G NL +R+DRM A P F ++TWGA
Sbjct: 16 KNHAMDKITDKIAALPAETNYCSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGA 75
Query: 189 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 368
GGSTA +L++A+ Q + + T +HLTCTNM + ID LE K+ G++N+LALRGDPP
Sbjct: 76 GGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAKALGIRNILALRGDPP 135
Query: 369 HGQD--------KFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ E F A DLV++IR HGDYF I +A YPE H D
Sbjct: 136 RRAEYRDSNEPKTDDDEEEEFHWAVDLVRYIRKTHGDYFCIGVAAYPEGHAD 187
[159][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 136 bits (343), Expect = 7e-31
Identities = 72/147 (48%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVG--DHWEAEEGGFSYATD 176
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HPDA
Sbjct: 177 LVKHIRTEFADYFDICVAGYPRGHPDA 203
[160][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 136 bits (342), Expect = 9e-31
Identities = 66/133 (49%), Positives = 90/133 (67%), Gaps = 2/133 (1%)
Frame = +3
Query: 111 GVVNLLERMDRMVAHSPSFCDITWGAGGSTA--DVTLDIAKKMQNTVGVETMMHLTCTNM 284
GV NL ER+DRM P + D+TWGAGGS++ + T +I + G++ MMHLTCT
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQQ 61
Query: 285 PVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFG 464
VE+ID+ L+ K G++N+LALRGD P ++ +GGF+ A DLV+HIR K+GDYF
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVRHIRGKYGDYFC 121
Query: 465 ITIAGYPEAHPDA 503
I +AGYPE H +A
Sbjct: 122 IAVAGYPEGHLEA 134
[161][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 135 bits (340), Expect = 2e-30
Identities = 75/160 (46%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 194
M+ I I+ A A + V S EFFP KTE+G NLLE+ + +++ P+FC +T+GAGG
Sbjct: 1 MQFIRDIY-AEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGG 59
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
T D TL I ++Q + MMHLTC N E++ L+ K G+QN+LALRGDPP G
Sbjct: 60 GTRDKTLGIVDRIQRHHNLPAMMHLTCVNSTREELGHVLDEAKGRGIQNILALRGDPPSG 119
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
D FV+ EGGF +R+LV IR + G F I AG+PE H
Sbjct: 120 GD-FVKTEGGFEFSRELVSFIRERSG--FSIGTAGFPEGH 156
[162][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 135 bits (340), Expect = 2e-30
Identities = 70/161 (43%), Positives = 106/161 (65%), Gaps = 3/161 (1%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ +KI E DP+K ++FEFFPP+T+ G NL+ R+ R+ P ITWGAGGS
Sbjct: 1 MKLSQKIAE---HDPSKPFYTFEFFPPRTDQGTENLIARISRLSTLDPLAISITWGAGGS 57
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T + +LD+A Q+ ++T++HLTCTNM IDD L+ +K G++ +LALRGDPP G+
Sbjct: 58 TKERSLDLASITQSQHRLDTILHLTCTNMEQGLIDDVLKDVKDRGIETILALRGDPPRGE 117
Query: 378 DKFVQVEGGFACARDLVKHIRA--KHGDYFGITIA-GYPEA 491
++++ + F A DLVK+IR ++ +F I +A G+ E+
Sbjct: 118 EEWIPSDPRFTHAIDLVKYIRGSQEYSSHFCIGVADGHTES 158
[163][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 134 bits (338), Expect = 3e-30
Identities = 71/146 (48%), Positives = 93/146 (63%), Gaps = 4/146 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC + E+I L K GL+N+LALRGDP D++ + EGGF A D
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIG--DQWEEEEGGFNYATD 176
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPD 500
LVKHIR + GDYF + +AGYP+ HP+
Sbjct: 177 LVKHIRNEFGDYFDVCVAGYPKGHPE 202
[164][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 134 bits (338), Expect = 3e-30
Identities = 67/139 (48%), Positives = 90/139 (64%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S EFFPPKTE G NLL RM+RM A +P F +TW AGG+TA TL++A Q + V
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
MHLTCTNM + ID+AL+ + ++N+LALRGDP G++ + F A DLV++I
Sbjct: 87 CMHLTCTNMNKDIIDEALKAARDADIRNILALRGDPAIGEEWSPDADTEFKYAVDLVRYI 146
Query: 438 RAKHGDYFGITIAGYPEAH 494
+ +GD F + +A YPE H
Sbjct: 147 KKNYGDDFCVGVAAYPEGH 165
[165][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 134 bits (338), Expect = 3e-30
Identities = 71/146 (48%), Positives = 93/146 (63%), Gaps = 4/146 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC + E+I L K GL+N+LALRGDP D++ + EGGF A D
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIG--DQWEEEEGGFNYATD 176
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPD 500
LVKHIR + GDYF + +AGYP+ HP+
Sbjct: 177 LVKHIRNEFGDYFDVCVAGYPKGHPE 202
[166][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 133 bits (334), Expect = 8e-30
Identities = 72/147 (48%), Positives = 94/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + + + IA N
Sbjct: 102 FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 161
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N+LALRG D++ VEGGF+ A D
Sbjct: 162 CGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGAVG---DQWEVVEGGFSYAAD 218
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV+HIR++ GDYF I +AGYP+ HPDA
Sbjct: 219 LVRHIRSEFGDYFDICVAGYPKGHPDA 245
[167][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 132 bits (333), Expect = 1e-29
Identities = 73/167 (43%), Positives = 99/167 (59%), Gaps = 5/167 (2%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
+K+ ++I A D + FS EFFPP+T G NL+ R +RMV P F DITW G
Sbjct: 30 VKLADRIE--AKIDRGERWFSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGD 87
Query: 198 TADV-----TLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 362
+ ++ IA N VG ETM+H++C N + I L+ K G++N+LALRGD
Sbjct: 88 PGNSDKETSSMSIACAALNYVGHETMLHMSCCNSTKDDIRRHLDKAKELGIRNILALRGD 147
Query: 363 PPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
P G D++ VE GF A D+VK IRA+ GDYF + +AGYP HPD+
Sbjct: 148 PIVG-DEWKYVEDGFNYATDMVKFIRAEFGDYFTVCVAGYPHGHPDS 193
[168][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 132 bits (333), Expect = 1e-29
Identities = 63/117 (53%), Positives = 79/117 (67%)
Frame = +3
Query: 159 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 338
P F DITW AGG T+D+T + K +Q GVET MHLTCTNMP KI+ AL K G +
Sbjct: 6 PEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAKEFGCR 65
Query: 339 NVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIG 509
NVLALRGDPP + GF+ A +LV++IR +GDYF I +AG+PE HP+A+G
Sbjct: 66 NVLALRGDPPAAGSPWEPHAAGFSHAFELVQYIREHYGDYFSIAVAGFPEGHPEAVG 122
[169][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 131 bits (330), Expect = 2e-29
Identities = 71/160 (44%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 194
M+ I I+ AA +D ++ V SFEFFPPKT++G LLE+ + ++ P FC +T+GAGG
Sbjct: 7 MQFIRDIY-AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGG 65
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
T D TL I ++Q + TM+HLTC N E++ D +E +S G++N+LALRGDPP G
Sbjct: 66 GTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNILALRGDPPGG 125
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
+F +GGF + LV +R G F I AG+PE H
Sbjct: 126 NGEFKMTDGGFEYSHQLVALLRELGG--FSIGTAGFPEGH 163
[170][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 131 bits (329), Expect = 3e-29
Identities = 73/147 (49%), Positives = 93/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + EGGF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPV-GAD-WEEEEGGFNYAVD 181
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ DYF I +AGYP HP+A
Sbjct: 182 LVKHIRSEFDDYFDICVAGYPTGHPEA 208
[171][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 130 bits (328), Expect = 4e-29
Identities = 69/163 (42%), Positives = 95/163 (58%), Gaps = 4/163 (2%)
Frame = +3
Query: 24 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 203
+IEKIH+ K FS EFFPP+T +G VNL+ R DRM P FCDITW G +
Sbjct: 21 LIEKIHKHIGK--KKKFFSLEFFPPRTPNGAVNLVARFDRMSQGGPLFCDITWHPAGDPS 78
Query: 204 ----DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 371
+ IA N G+ETM+H+TC N+ + + L+ K+ G++N+LALRGDPP
Sbjct: 79 GDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKKAKNLGIRNILALRGDPPK 138
Query: 372 GQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
G + ++ + D+VK IR +YF I +AGYP+ HPD
Sbjct: 139 G-EVWMASDENLRFGADMVKFIRKHFQNYFTICVAGYPQGHPD 180
[172][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 130 bits (328), Expect = 4e-29
Identities = 71/183 (38%), Positives = 101/183 (55%), Gaps = 39/183 (21%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRM-VAHSPSFCDITWGAGGSTADVTLDIAKKMQ----- 236
+SFEFFPPKT G+ NL R+ RM V PS+ +TWGAGG+T +L++A ++Q
Sbjct: 40 WSFEFFPPKTSQGLANLYNRIARMHVNLEPSWIHVTWGAGGTTGGKSLELAGRIQKGKLD 99
Query: 237 ----------NTVGVETM-----------------------MHLTCTNMPVEKIDDALET 317
N +G T +HLTCTN+ +D L+T
Sbjct: 100 PDVELVQTEINHIGSGTQQHIENVKGGQEWEQERADPCDVCLHLTCTNVEKSSLDQTLDT 159
Query: 318 IKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
K G++N+LALRGDPP G++ ++ + F A DLV++IR +HG+YF I +AGYPE H
Sbjct: 160 AKRLGIKNILALRGDPPRGEEYWIAADKRFQHATDLVRYIRQRHGNYFCIGVAGYPEGHA 219
Query: 498 DAI 506
D +
Sbjct: 220 DYV 222
[173][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 130 bits (326), Expect = 7e-29
Identities = 68/147 (46%), Positives = 95/147 (64%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADVT-LDIAKKMQNT 242
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + + + IA +
Sbjct: 57 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 116
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC + ++I L K GL+N++ALRGDP D++ + EGGF A D
Sbjct: 117 CGLETVLHMTCCHQTRDEITRHLHKAKRLGLKNIMALRGDPIG--DEWEEEEGGFNHAVD 174
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF + +AGYP+ HP+A
Sbjct: 175 LVKHIRSEFGDYFDVCVAGYPKGHPEA 201
[174][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 130 bits (326), Expect = 7e-29
Identities = 65/151 (43%), Positives = 94/151 (62%), Gaps = 1/151 (0%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV GFA
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGAFVPHPDGFA 129
Query: 411 CARDLVKHIRAKHGDY-FGITIAGYPEAHPD 500
A +LV IR++ + F + A YPE HP+
Sbjct: 130 HASELVAFIRSQPERWRFCVGAAAYPEGHPE 160
[175][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 129 bits (325), Expect = 9e-29
Identities = 69/140 (49%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S EFFPPKT+ G NL RM RM A +P F ITWGAGG+TA TL++A Q + V
Sbjct: 36 SLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTAKKTLELATVAQRELNVPV 95
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG-FACARDLVKH 434
MHLTCTN E ID+AL+ ++N+LALRGDPP G++ E F A DLV++
Sbjct: 96 CMHLTCTNTNKEIIDEALKLAHEADIRNILALRGDPPVGEEWETPSESSEFQHAVDLVRY 155
Query: 435 IRAKHGDYFGITIAGYPEAH 494
I+ K+ D F + +A YPE H
Sbjct: 156 IKEKYNDDFCVGVAAYPEGH 175
[176][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 129 bits (324), Expect = 1e-28
Identities = 72/147 (48%), Positives = 92/147 (62%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + E GF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPV-GAD-WEEEEDGFNYAID 181
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ DYF I +AGYP HP+A
Sbjct: 182 LVKHIRSEFDDYFDICVAGYPTGHPEA 208
[177][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 129 bits (324), Expect = 1e-28
Identities = 72/147 (48%), Positives = 92/147 (62%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E+++HLTC N +KI L K GL+N++ALRGDP G D + + E GF A D
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPV-GAD-WEEEEDGFNYAID 181
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ DYF I +AGYP HP+A
Sbjct: 182 LVKHIRSEFDDYFDICVAGYPTGHPEA 208
[178][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 129 bits (324), Expect = 1e-28
Identities = 61/142 (42%), Positives = 89/142 (62%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPK E+G L + + + P+F +T+GAGGST D T ++ K++ VG+
Sbjct: 15 SFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTRNVVKRIHEEVGLTV 74
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
M HLTC E++ + LE + G++N+LALRGD PH F EG + A++LV+ I
Sbjct: 75 MAHLTCIAHTREELIEILEDYRGIGIENILALRGDVPHDTPDFRPPEGACSYAKELVELI 134
Query: 438 RAKHGDYFGITIAGYPEAHPDA 503
R + GDYF + +A YPE HP++
Sbjct: 135 RERFGDYFSVGVASYPEGHPES 156
[179][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 129 bits (323), Expect = 1e-28
Identities = 69/147 (46%), Positives = 94/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA +
Sbjct: 54 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDY 113
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC+ ++I L K GL+N+LALRGDP D++ + E F+ A D
Sbjct: 114 CGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDPI--GDEWEEEENCFSHAVD 171
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR++ GDYF I +AGYP+ HP+A
Sbjct: 172 LVKHIRSEFGDYFDICVAGYPKGHPEA 198
[180][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 128 bits (322), Expect = 2e-28
Identities = 71/147 (48%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC N E I L+ K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETLLHMTCCNQTKEDITKHLQKAKRLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP HPDA
Sbjct: 172 LVKHIRHEFEDYFDICVAGYPRGHPDA 198
[181][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 128 bits (322), Expect = 2e-28
Identities = 63/154 (40%), Positives = 90/154 (58%)
Frame = +3
Query: 36 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTL 215
+H + + SFEFFPPK E+ +L + + +P++ +T+GAGGST +T
Sbjct: 1 MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH 60
Query: 216 DIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQV 395
D+ K+QN G+ + HLTC E+I D L+ +G+ N++ALRGDPP GQ F Q
Sbjct: 61 DLVVKLQNETGLTIVSHLTCVGSTKEEIGDILKRYDKSGIHNIMALRGDPPKGQQDFQQT 120
Query: 396 EGGFACARDLVKHIRAKHGDYFGITIAGYPEAHP 497
E GFA A +LV I+ K GI +AG+PE HP
Sbjct: 121 ENGFAYAGELVGFIK-KEFPKMGIGVAGFPEGHP 153
[182][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 128 bits (321), Expect = 3e-28
Identities = 64/151 (42%), Positives = 93/151 (61%), Gaps = 1/151 (0%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV GF
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGGFVPHPDGFT 129
Query: 411 CARDLVKHIRAKHGDY-FGITIAGYPEAHPD 500
A +LV IR++ + F + A YPE HP+
Sbjct: 130 HASELVAFIRSQPERWRFCVGAAAYPEGHPE 160
[183][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 128 bits (321), Expect = 3e-28
Identities = 62/146 (42%), Positives = 92/146 (63%)
Frame = +3
Query: 57 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 236
+P+ FSFEFFPPKT++G NLL+ ++ + P F +T+GAGGST + TL + +++
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 237 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 416
T G+E+M HLTC +++ + L+ +++ L NVL LRGDPP GQ F GGF A
Sbjct: 105 QTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNVLVLRGDPPRGQTTFAPTPGGFRYA 164
Query: 417 RDLVKHIRAKHGDYFGITIAGYPEAH 494
+LV+ IR + + F + A YPE H
Sbjct: 165 SELVEFIREEDFN-FCVGGACYPEGH 189
[184][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 128 bits (321), Expect = 3e-28
Identities = 63/146 (43%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD----VTLDIAKKMQNT 242
FS EFFPP+T +G VNLL DR+ + P FCD+TW G + ++ IA N
Sbjct: 12 FSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTSSMTIASTALNY 71
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ETM+H+TC N + L K+ G++N+LALRGDPP G++ + +E G A D
Sbjct: 72 CGLETMLHMTCANQTKASVTKNLHKAKTLGIRNILALRGDPPDGEE-WKALEDGLAYGAD 130
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPD 500
+V+HIR + F I +AGYP HPD
Sbjct: 131 MVRHIRNNFDESFTICVAGYPAGHPD 156
[185][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 127 bits (318), Expect = 6e-28
Identities = 74/177 (41%), Positives = 99/177 (55%), Gaps = 30/177 (16%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
K S E+FPP+T +GV NL RM RM P+F D+TWGAGGSTA+++L +A NT
Sbjct: 39 KPFVSLEYFPPRTAEGVQNLHARMHRMRDTLQPAFTDMTWGAGGSTAELSLQLALYAHNT 98
Query: 243 VGVETMMHLTCTNM---------------------------PVEKIDDALETIKSNGLQN 341
G +H+TCTN+ P E + AL+ G++N
Sbjct: 99 -GHVANLHMTCTNLDSGKSSTSTSSSSEHNGNASDDVASADPRETLRRALQQAHDGGIRN 157
Query: 342 VLALRGDPPHGQDKFVQVEGGFACARDLVKHIRA--KHGDYFGITIAGYPEAHPDAI 506
++ALRGDPP GQ+ + EGGF CA DLV+ IR+ G F + +AGYPE HP+AI
Sbjct: 158 LVALRGDPPAGQETWTATEGGFTCALDLVEFIRSLPDIGADFHLAVAGYPEGHPNAI 214
[186][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 126 bits (317), Expect = 7e-28
Identities = 66/153 (43%), Positives = 88/153 (57%), Gaps = 4/153 (2%)
Frame = +3
Query: 57 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 236
+ N FS EFFPP+TE G NL+ R DRM A P F DITW G + + K+
Sbjct: 27 ESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGGPLFVDITWHPAGDPGSDKITSSTKIA 86
Query: 237 NTV----GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGG 404
TV G++TM+H+TC E I LE K+ G++N+LALRGD + + EGG
Sbjct: 87 GTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKNLGIRNILALRGD---ADESWGYQEGG 143
Query: 405 FACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
F DLV+ I+ ++GD F I +AGYP HPD+
Sbjct: 144 FNYGVDLVRFIKQEYGDAFSICVAGYPNGHPDS 176
[187][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 125 bits (315), Expect = 1e-27
Identities = 68/148 (45%), Positives = 95/148 (64%), Gaps = 5/148 (3%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 251
+SFEFFPPKTE G+ NLL R+DRM P F D+TWG+ ++A T+ +A Q +GV
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPLFIDVTWGSDKTSAR-TMALASHAQKYLGV 99
Query: 252 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV--QVEGGFACAR-- 419
+ ++HL+C M +++ L+ K G+ N+LALRGDPP + + V GG C R
Sbjct: 100 DVLLHLSCQGMTRDQLIRVLDQAKVLGIHNILALRGDPPKAKKHWQVGDVSGG-ECERAI 158
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDA 503
DLV+ IR +GDYFGI +AG+PE HP +
Sbjct: 159 DLVRLIRNTYGDYFGIAVAGHPEGHPSS 186
[188][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 125 bits (314), Expect = 2e-27
Identities = 64/149 (42%), Positives = 90/149 (60%), Gaps = 1/149 (0%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+D+ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIDLVKR 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
++ VE M H+TC E+I L+ + G+QNVLALRGD P GQ FV GF
Sbjct: 70 LKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAPRGQSAFVPHPDGFT 129
Query: 411 CARDLVKHIRAKHGDY-FGITIAGYPEAH 494
A +LV IR++ + F + A YPE H
Sbjct: 130 HASELVAFIRSRPERWRFCVGAAAYPEGH 158
[189][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 125 bits (313), Expect = 2e-27
Identities = 70/149 (46%), Positives = 90/149 (60%), Gaps = 4/149 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC N E I L K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDAIG 509
LV HIR + DYF I +AGYP HP+A G
Sbjct: 172 LVTHIRHEFDDYFDICVAGYPRGHPEAEG 200
[190][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 125 bits (313), Expect = 2e-27
Identities = 70/149 (46%), Positives = 90/149 (60%), Gaps = 4/149 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC N E I L K GL+N++ALRGDP G++ + E GF A D
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPT-GEEWEEEAE-GFNYAVD 171
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDAIG 509
LV HIR + DYF I +AGYP HP+A G
Sbjct: 172 LVTHIRHEFDDYFDICVAGYPRGHPEAEG 200
[191][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 124 bits (312), Expect = 3e-27
Identities = 66/162 (40%), Positives = 96/162 (59%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK + +I+ +A V+SFEFFPPKT+DG + L+ + + P F +T+GAGGS
Sbjct: 1 MKKVSEIYGSAKGP----VYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGS 56
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D T I ++ T+ H TC ++I L+ I+S+G+ N++ALRGDPP G+
Sbjct: 57 TRDKTAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGE 116
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
KF + EGGF A +L+ IR++ D F I YPE HP+A
Sbjct: 117 GKFKKTEGGFENATELISFIRSEKLD-FCIGGGCYPEKHPNA 157
[192][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 124 bits (312), Expect = 3e-27
Identities = 64/149 (42%), Positives = 91/149 (61%), Gaps = 1/149 (0%)
Frame = +3
Query: 51 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 230
A + + VFSFEFFPPKT+DGV L E ++ + +P++ +T+GAGGST TL++ K+
Sbjct: 10 ARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQRTLELVKR 69
Query: 231 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFA 410
++ VE M HLTC E++ L+ + G+QNVLALRGDPP G+ F GF
Sbjct: 70 LKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPPRGETSFSPHPEGFR 129
Query: 411 CARDLVKHIRAKHGDY-FGITIAGYPEAH 494
A +LV IR++ + F + A YPE H
Sbjct: 130 YASELVAFIRSRPERWRFCLGAAAYPEGH 158
[193][TOP]
>UniRef100_C1XL88 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus ruber DSM
1279 RepID=C1XL88_MEIRU
Length = 291
Score = 124 bits (312), Expect = 3e-27
Identities = 64/147 (43%), Positives = 86/147 (58%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 245
K +FSFEFFPPKT G L + + P+F IT+GAGGS + T + A ++QN V
Sbjct: 11 KPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTAEWAARIQNEV 70
Query: 246 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 425
G+ M HLTC E++ L G++N++ALRGDPP G +F V GGF A +L
Sbjct: 71 GLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPPQGAREFQPVAGGFRYAAEL 130
Query: 426 VKHIRAKHGDYFGITIAGYPEAHPDAI 506
V IRA+ GD F + YPE H +A+
Sbjct: 131 VALIRAEFGDRFTVAGGAYPEGHIEAV 157
[194][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 123 bits (309), Expect = 6e-27
Identities = 68/147 (46%), Positives = 94/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC + ++I L+ K GL+N++ALRGDP G++ +V+ GF A D
Sbjct: 122 CGLETILHMTCCHQTRDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVD-GFNHAVD 179
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP+ HP+A
Sbjct: 180 LVKHIRNEFDDYFDICVAGYPKGHPEA 206
[195][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 123 bits (309), Expect = 6e-27
Identities = 68/147 (46%), Positives = 94/147 (63%), Gaps = 4/147 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T + VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 62 FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY 121
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC + ++I L+ K GL+N++ALRGDP G++ +V+ GF A D
Sbjct: 122 CGLETIVHMTCCHQTKDEITGHLQKAKRLGLKNIMALRGDPV-GEEWEEEVD-GFNHAVD 179
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LVKHIR + DYF I +AGYP+ HP+A
Sbjct: 180 LVKHIRNEFDDYFDICVAGYPKGHPEA 206
[196][TOP]
>UniRef100_UPI00005884BD PREDICTED: similar to Mthfr-prov protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI00005884BD
Length = 326
Score = 123 bits (309), Expect = 6e-27
Identities = 72/167 (43%), Positives = 94/167 (56%), Gaps = 4/167 (2%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP---SFCDITWGA 188
M++ EKI AS FS EFFPP+T G VNL+ R M WG
Sbjct: 56 MRLSEKIANRIASKDRW--FSLEFFPPRTASGAVNLVGRYVHMGGGGEIKVMEMYYPWGG 113
Query: 189 GGSTAD-VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 365
GG+ + V+++IA+ M N G++TM+H+ C + E I LE K G++N+LALRGD
Sbjct: 114 GGAGEEQVSMEIARTMLNYCGLDTMLHMCCVSQSAEVITRHLEWAKECGIRNILALRGDV 173
Query: 366 PHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
P D++ GGF A DLVKHIR GD F I +AGYP HPDA+
Sbjct: 174 PGHTDEWEPTPGGFNYATDLVKHIRKVFGDDFVIAVAGYPSGHPDAV 220
[197][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 123 bits (309), Expect = 6e-27
Identities = 61/143 (42%), Positives = 89/143 (62%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKTE+ NL + ++ P FC +T+GAGGST + T + A ++Q T G+E
Sbjct: 15 FSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETALEIQQTTGIE 74
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
HL+C I + LE +S+G+++++ALRGD P G + G F A +LV+
Sbjct: 75 CAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSG----MLSAGEFRHANELVEF 130
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IR++ G++F I +A YPE HP A
Sbjct: 131 IRSETGNHFHIEVACYPEVHPQA 153
[198][TOP]
>UniRef100_C1SKU9 Methylenetetrahydrofolate reductase n=1 Tax=Denitrovibrio
acetiphilus DSM 12809 RepID=C1SKU9_9BACT
Length = 284
Score = 123 bits (309), Expect = 6e-27
Identities = 61/142 (42%), Positives = 87/142 (61%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPK ++ L E + ++ ++P F +T+GAGGST + TL+ K+M+
Sbjct: 14 SFEFFPPKKQESEQVLFETIKKLRRYNPEFVSVTYGAGGSTTEKTLEWTKRMKEDHDYSV 73
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
MMH TC ID A +++K + + N+LALRGD P G +F + F A DLV++I
Sbjct: 74 MMHFTCIGADAAVIDSATQSLKESRVDNILALRGDIPAGTTEFKPTK-DFQYAADLVRYI 132
Query: 438 RAKHGDYFGITIAGYPEAHPDA 503
R GD+F I +AGYPE HP+A
Sbjct: 133 RKTTGDHFSIGVAGYPEKHPEA 154
[199][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 123 bits (309), Expect = 6e-27
Identities = 66/162 (40%), Positives = 97/162 (59%), Gaps = 1/162 (0%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 194
MK+ E++ + D + +SFEFFPPKT G+ NL RM RM P F +TW + G
Sbjct: 1 MKISEQLEQLPKDD---IHYSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAG 57
Query: 195 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 374
S+A +L + +Q+ GV + +H+TC+N+ E I L+ K+ G++N+LALRGDPP
Sbjct: 58 SSAAESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNILALRGDPPLK 117
Query: 375 QDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ + + A DLV+ IR ++GDYF I +A YPE H D
Sbjct: 118 TEHWNAQKFEMEHAVDLVRFIREEYGDYFCIGVAAYPEGHAD 159
[200][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 123 bits (309), Expect = 6e-27
Identities = 60/142 (42%), Positives = 90/142 (63%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPKTE+G L E + ++ +P+F +T+GAGGST D T +I +K+ +
Sbjct: 15 SFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTRNIVQKIHEETNLTV 74
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
M HLTC E++ D L+ K+ G++N+LALRGD P + + +G A++LV+ I
Sbjct: 75 MAHLTCIAHTREELIDILQDYKNIGIENILALRGDVPRDKPDWRPPKGACKYAKELVELI 134
Query: 438 RAKHGDYFGITIAGYPEAHPDA 503
R + GD+F I +A YPE HP++
Sbjct: 135 RKEFGDWFSIGVASYPEGHPES 156
[201][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 123 bits (308), Expect = 8e-27
Identities = 66/173 (38%), Positives = 100/173 (57%), Gaps = 17/173 (9%)
Frame = +3
Query: 21 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 197
++ EK+++ S + V+S EFFPP+T G+ NL R+ RM A P + +TWG GGS
Sbjct: 11 RIDEKLND---STQDAYVWSLEFFPPRTALGLANLCARVARMSEALQPGWVHVTWGTGGS 67
Query: 198 TADVTLDIAKKMQNTV----------------GVETMMHLTCTNMPVEKIDDALETIKSN 329
T D ++++A ++Q V + +HLTCTN+ +D L+ +
Sbjct: 68 TRDASMELAARVQKGVYDPLEDYTNVKERRKGACDVCLHLTCTNVERAYLDATLDEARQI 127
Query: 330 GLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPE 488
G++N+LALRGDPP + +V + A DLV++IR +HGDYF I +AGYPE
Sbjct: 128 GIRNILALRGDPPRSDEYWVATDQRLQNATDLVRYIRERHGDYFCIGVAGYPE 180
[202][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 122 bits (307), Expect = 1e-26
Identities = 65/162 (40%), Positives = 91/162 (56%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+I+K+ K+ SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KISISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T + T DI KK+ + M HLTC ++I L+ K G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENILALRGDMPLNF 114
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+K G A +LV IR + DYF I +A YPE HP++
Sbjct: 115 EKTDIPSDGCKHASELVSLIRENYKDYFCIAVASYPEGHPES 156
[203][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 122 bits (306), Expect = 1e-26
Identities = 62/143 (43%), Positives = 87/143 (60%), Gaps = 1/143 (0%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFPPKT +G L + + +P+F +T+GAGGST + T+ + K++ +
Sbjct: 15 SFEFFPPKTPEGEDQLFRTIKDLEKLNPTFVSVTYGAGGSTRERTIRVVKRIHEQCNLTV 74
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK-FVQVEGGFACARDLVKH 434
M HLTC ++I D L+ K G+QN+LALRGD P GQ++ FV G A +LV
Sbjct: 75 MAHLTCIGHSKKEIYDILKGYKDIGIQNILALRGDIPQGQEESFVFPPDGCRYANELVSF 134
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IR + GDYF I +A YPE HP++
Sbjct: 135 IREQFGDYFSIGVAAYPEGHPES 157
[204][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 121 bits (304), Expect = 2e-26
Identities = 66/162 (40%), Positives = 97/162 (59%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+F +VE GF A +LV IR++ D F I YPE HP+A
Sbjct: 134 GEFKKVENGFGNATELVSFIRSEKLD-FCIGGGCYPEKHPNA 174
[205][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 121 bits (304), Expect = 2e-26
Identities = 66/162 (40%), Positives = 97/162 (59%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+F +VE GF A +LV IR++ D F I YPE HP+A
Sbjct: 134 GEFKKVENGFGNATELVSFIRSEKLD-FCIGGGCYPEKHPNA 174
[206][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 121 bits (304), Expect = 2e-26
Identities = 65/162 (40%), Positives = 95/162 (58%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+++K+ + KV SFEFFPPKT++ +L + ++ + +P+F +T+GAGGS
Sbjct: 1 MKIVDKLKK------EKVSISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGS 54
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T + T DI KK+ + M HLTC ++I LE K+ G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENILALRGDIPLSF 114
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
DK G A +LV I+ GDYF I +A YPE HP++
Sbjct: 115 DKKDIPLDGCKHAFELVSLIKDNFGDYFCIAVASYPEGHPES 156
[207][TOP]
>UniRef100_C8X270 5,10-methylenetetrahydrofolate reductase n=1 Tax=Desulfohalobium
retbaense DSM 5692 RepID=C8X270_9DELT
Length = 293
Score = 121 bits (304), Expect = 2e-26
Identities = 62/148 (41%), Positives = 87/148 (58%)
Frame = +3
Query: 60 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 239
P K S EFFPPK E E + ++ + P F +T+GAGGST D TL + +++
Sbjct: 9 PGKKFISLEFFPPKDEGNWPGFFEEVHQLASMDPLFVSVTYGAGGSTQDNTLRLVSRLKQ 68
Query: 240 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 419
+G+E M HLTC + D + +++++ + NVLALRGDPP GQD FV F A
Sbjct: 69 -MGLEPMAHLTCVGASAATLHDFMRSLQASDIDNVLALRGDPPQGQDTFVPDNADFQHAS 127
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDA 503
DLV+ +R +H GI +AGYPE H +A
Sbjct: 128 DLVRFLR-EHYPECGIGVAGYPEGHQEA 154
[208][TOP]
>UniRef100_A1VEZ2 Methylenetetrahydrofolate reductase n=3 Tax=Desulfovibrio vulgaris
RepID=A1VEZ2_DESVV
Length = 291
Score = 121 bits (304), Expect = 2e-26
Identities = 66/163 (40%), Positives = 94/163 (57%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ E I + + +S EFFPPK + ++R+ A P F +T+GAGG
Sbjct: 1 MKIAEAIERQS-----RPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGG 55
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D TLDI ++N +G+E M HLTC E+I L ++ G++NVLALRGDPP GQ
Sbjct: 56 TQDNTLDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQ 115
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
+ F A DLV+ +R + + FGI +AGYP AHP+++
Sbjct: 116 QVDWET-AEFRYASDLVRFVRNEFPE-FGIGVAGYPAAHPESV 156
[209][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 121 bits (303), Expect = 3e-26
Identities = 65/162 (40%), Positives = 92/162 (56%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+I+K+ KV SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KVSISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T + T DI KK+ + M HLTC ++I L+ + G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENILALRGDIPLNF 114
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+K + G A +LV IR + DYF I +A YPE HP++
Sbjct: 115 EKSDILSDGCKHASELVSLIRETYKDYFCIAVASYPEGHPES 156
[210][TOP]
>UniRef100_A6C2T8 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces maris DSM
8797 RepID=A6C2T8_9PLAN
Length = 297
Score = 120 bits (302), Expect = 4e-26
Identities = 59/142 (41%), Positives = 85/142 (59%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S E FPP+ E G L + ++ +V + P+F T+GAGGST+ T+++ +QN +
Sbjct: 15 SVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTIELCALIQNQLHNTA 74
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
H TC N E++ + L+ G+ N++ALRGDPP GQ+ FV +GG A +LV I
Sbjct: 75 TAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPADGGLKYANELVSLI 134
Query: 438 RAKHGDYFGITIAGYPEAHPDA 503
R KH GI +AGYPE HP+A
Sbjct: 135 R-KHFPDMGIGVAGYPECHPEA 155
[211][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 120 bits (301), Expect = 5e-26
Identities = 64/136 (47%), Positives = 88/136 (64%), Gaps = 6/136 (4%)
Frame = +3
Query: 111 GVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMP 287
G NL +R+DRM A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM
Sbjct: 2 GFSNLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELALTTCLHLTCTNMS 61
Query: 288 VEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV--QVEGG---FACARDLVKHIRAKHG 452
+ ID ALE K+ G++N+LALRGDPP + + EG F A DLV++I+ HG
Sbjct: 62 RKLIDKALEDAKALGIRNILALRGDPPRPGEYAIPDDSEGDVNEFTWAIDLVRYIKLNHG 121
Query: 453 DYFGITIAGYPEAHPD 500
DYF + +A YPE H +
Sbjct: 122 DYFCVGVAAYPEGHAE 137
[212][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 119 bits (298), Expect = 1e-25
Identities = 65/138 (47%), Positives = 84/138 (60%), Gaps = 4/138 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 176
Query: 423 LVKHIRAKHGDYFGITIA 476
LVKHIR + DYF I +A
Sbjct: 177 LVKHIRTEFADYFDICVA 194
[213][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 119 bits (298), Expect = 1e-25
Identities = 65/138 (47%), Positives = 84/138 (60%), Gaps = 4/138 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 242
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ET++H+TC E+I L K GL+N++ALRGDP D + EGGF+ A D
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPV--GDHWEAEEGGFSYATD 176
Query: 423 LVKHIRAKHGDYFGITIA 476
LVKHIR + DYF I +A
Sbjct: 177 LVKHIRTEFADYFDICVA 194
[214][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 119 bits (297), Expect = 2e-25
Identities = 57/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 66 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 245
K V SFE FPPK + + ++ +++ P F +T+GAGGS D T++IA K++N
Sbjct: 11 KPVISFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTIEIASKIKNEY 70
Query: 246 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDL 425
G+E+M HLTC E+ID L +++ + L+N+LALRGDPP Q F F A +L
Sbjct: 71 GIESMAHLTCVGHSKEEIDALLTSMREHNLENILALRGDPPANQPDFDFSNNAFKYANEL 130
Query: 426 VKHIRAKHGDYFGITIAGYPEAH 494
+ H+R ++ + F I A Y E H
Sbjct: 131 IAHVRKQNRNDFCIAAAAYVEGH 153
[215][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 118 bits (296), Expect = 2e-25
Identities = 60/148 (40%), Positives = 85/148 (57%)
Frame = +3
Query: 54 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 233
S + +FSFEFFPPK D L + ++ +PS+ +T+GAGGST T D+ K+
Sbjct: 8 SSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRTHDLVTKI 67
Query: 234 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFAC 413
+ G+ + HLTC ++I D L T ++NG+ NVLALRGD P G + + F
Sbjct: 68 RKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLPPGTTSYSEATKDFPH 127
Query: 414 ARDLVKHIRAKHGDYFGITIAGYPEAHP 497
A DLV+ I+ FGI +AG+PE HP
Sbjct: 128 AIDLVRFIKTNFPS-FGIGVAGFPEGHP 154
[216][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 118 bits (295), Expect = 3e-25
Identities = 62/143 (43%), Positives = 82/143 (57%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKTE G + L D + A +P F +T+GAGGST D TL+ + G+
Sbjct: 40 FSFEFFPPKTEQGKIKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETVFSLHQQ-GIS 98
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T HL+C +I + L+T K+NG+ ++ALRGD P G + G A +LV
Sbjct: 99 TAPHLSCVGGTRAEISELLDTYKANGINRIVALRGDLPSG----MGAAGELRYANELVSF 154
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IR GDYF + +A YPE HP A
Sbjct: 155 IREHSGDYFNLEVAAYPEFHPQA 177
[217][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 117 bits (294), Expect = 3e-25
Identities = 60/143 (41%), Positives = 83/143 (58%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT +G+ L D++ P F +T+GAGGST + T+D + G+
Sbjct: 11 FSFEFFPPKTPEGMEKLQVVRDKLAKRKPDFFSVTYGAGGSTRERTIDTVLTLHRQ-GIS 69
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
T HL+C E I + L+ +SNG+Q ++ALRGD P G + G A +LV +
Sbjct: 70 TAPHLSCIGATKESIGELLDLYRSNGIQRIVALRGDLPSG----MGAPGELRYANELVSY 125
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IR + GD+F I +A YPE HP A
Sbjct: 126 IRERTGDHFSIEVAAYPEFHPQA 148
[218][TOP]
>UniRef100_B3QV58 Methylenetetrahydrofolate reductase n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QV58_CHLT3
Length = 294
Score = 117 bits (294), Expect = 3e-25
Identities = 56/149 (37%), Positives = 86/149 (57%)
Frame = +3
Query: 60 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 239
P+K FSFEF+PPK ++ L + ++ +P++ +T+GAGGST D T ++ ++
Sbjct: 9 PDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTHNLVVRISK 68
Query: 240 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 419
+ + HLTC +I LE NG+ N+LALRGDPP G F + GFA A
Sbjct: 69 ETNIPVVSHLTCVGSSKSEIHTILERYAENGITNILALRGDPPKGSTTFEKPADGFAYAN 128
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDAI 506
+LV I+ K+ G+ +AG+PE HP+ +
Sbjct: 129 ELVAFIK-KNFPQIGVGVAGFPEGHPETL 156
[219][TOP]
>UniRef100_A5KL25 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus torques
ATCC 27756 RepID=A5KL25_9FIRM
Length = 289
Score = 117 bits (293), Expect = 5e-25
Identities = 64/159 (40%), Positives = 96/159 (60%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+I+++ E +K+ SFE FPPKT+ G ++ D M +P+F +T+GAGG
Sbjct: 1 MKIIDRLKE------DKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGG 54
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T+ T IA +++ +GV ++ HLTC + +E++ D +E +K NG++N+LALRGD P G
Sbjct: 55 TSKNTAKIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGM 114
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAH 494
F A +L++ IR KHGD F I A YPE H
Sbjct: 115 P--FPNGNRFRYAYELIEEIR-KHGD-FCIGAACYPEGH 149
[220][TOP]
>UniRef100_Q7UNJ7 Methylenetetrahydrofolate reductase n=1 Tax=Rhodopirellula baltica
RepID=Q7UNJ7_RHOBA
Length = 294
Score = 117 bits (292), Expect = 6e-25
Identities = 57/143 (39%), Positives = 86/143 (60%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFE FPPKT +GV L + ++R++ P + T+GAGGS+ TL++ +K++ +
Sbjct: 19 SFELFPPKTSEGVELLCKNVERLMQFGPKYFTCTYGAGGSSQGTTLEVLQKVKQITKLPV 78
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
HLTC V++++ L G+ ++ALRGDPP G +F EGG A +LV+ I
Sbjct: 79 ASHLTCVGSTVKELEAYLTEAGRIGVDYIVALRGDPPKGTTQFEVTEGGLKYANELVELI 138
Query: 438 RAKHGDYFGITIAGYPEAHPDAI 506
R + GD GI +AGYPE H +A+
Sbjct: 139 RGRFGD-LGIAVAGYPETHQEAV 160
[221][TOP]
>UniRef100_C1ZF18 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces
limnophilus DSM 3776 RepID=C1ZF18_PLALI
Length = 310
Score = 116 bits (291), Expect = 8e-25
Identities = 61/143 (42%), Positives = 86/143 (60%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S E FPPKT +G L + + ++P+F T+GAGGST TLD +++ + VGV
Sbjct: 27 SIEIFPPKTAEGDAALRQALQEFSTYNPAFVSCTYGAGGSTRSRTLDWCREIIDRVGVAP 86
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
H TC +++ D L G++N++ALRGD P G+ +F VEGGF+ AR LV+ I
Sbjct: 87 TAHFTCVGSNSDELIDWLGQAWQLGVRNIMALRGDVPQGETEFKAVEGGFSHARQLVELI 146
Query: 438 RAKHGDYFGITIAGYPEAHPDAI 506
R K GI +AGYPE HP+A+
Sbjct: 147 R-KEFPEMGIGVAGYPEKHPEAV 168
[222][TOP]
>UniRef100_B5JTS2 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
HTCC5015 RepID=B5JTS2_9GAMM
Length = 277
Score = 116 bits (291), Expect = 8e-25
Identities = 64/143 (44%), Positives = 80/143 (55%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT+ G LL + +P F +T+GAGGST D TLD +Q G
Sbjct: 6 FSFEFFPPKTDRGREKLLGVHRELAELNPEFFSVTFGAGGSTRDGTLDTVTAIQER-GSA 64
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
H++C +ID L T + G+ ++ALRGD P GQ G FA A DLV+H
Sbjct: 65 AAPHISCIGSSKSEIDQLLNTYQERGINRLVALRGDMPSGQ----YAAGDFAYANDLVEH 120
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IR GD+F I +A YPE HP A
Sbjct: 121 IRTTTGDHFHIEVAAYPEFHPQA 143
[223][TOP]
>UniRef100_C4XPB4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
magneticus RS-1 RepID=C4XPB4_DESMR
Length = 330
Score = 115 bits (289), Expect = 1e-24
Identities = 60/143 (41%), Positives = 84/143 (58%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S EFFPPK + +++++ P F +T+GAGGST TL+I +++ G+E
Sbjct: 55 SLEFFPPKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTLEIVSRLKTAYGLEP 114
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
M HLTC +KI L + G+ NVLALRGDPP GQ+ FV F A DLV I
Sbjct: 115 MAHLTCVGASKDKIRGFLGALAQAGVDNVLALRGDPPKGQETFVPDSEDFQHASDLVAFI 174
Query: 438 RAKHGDYFGITIAGYPEAHPDAI 506
RA++ + + +AGYPE HP+A+
Sbjct: 175 RAEYPN-LCLGVAGYPECHPEAV 196
[224][TOP]
>UniRef100_B8DJ94 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio vulgaris
str. 'Miyazaki F' RepID=B8DJ94_DESVM
Length = 291
Score = 115 bits (288), Expect = 2e-24
Identities = 66/162 (40%), Positives = 94/162 (58%)
Frame = +3
Query: 18 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 197
MK+ ++I AA++ P +S EFFPPK + ++R+ A P F +T+GAGGS
Sbjct: 1 MKIRDRI--AASTRP---FYSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGS 55
Query: 198 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 377
T D TL+I ++N +G+E M HLTC E+I D L ++ + NVLALRGD P GQ
Sbjct: 56 TQDNTLEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQ 115
Query: 378 DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
D F A DLV+ R + + G+ +AGYP AHP++
Sbjct: 116 D-IDWDTAEFRYAADLVRFTRNEQPE-MGVGVAGYPAAHPES 155
[225][TOP]
>UniRef100_B4EE72 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia J2315 RepID=B4EE72_BURCJ
Length = 276
Score = 115 bits (287), Expect = 2e-24
Identities = 61/145 (42%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQS 143
[226][TOP]
>UniRef100_B1JTJ6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia MC0-3 RepID=B1JTJ6_BURCC
Length = 276
Score = 115 bits (287), Expect = 2e-24
Identities = 61/145 (42%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQS 143
[227][TOP]
>UniRef100_A4SE12 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SE12_PROVI
Length = 289
Score = 115 bits (287), Expect = 2e-24
Identities = 59/146 (40%), Positives = 84/146 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
+K VFSFEFFPPK + L E + + +PS+ +T+GAGGST T D+ ++Q
Sbjct: 11 HKPVFSFEFFPPKKDADWETLFETITALSPLNPSYVSVTYGAGGSTRTRTHDLVTRIQKE 70
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+ + HLTC + + LE +S+G+ NVLALRGD P G + F A D
Sbjct: 71 TGLSVVSHLTCIASTSGETGEILENYQSHGINNVLALRGDKPTGTESIADAVKDFPHAID 130
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPD 500
LV+ I+ H D G+ +AG+PE HP+
Sbjct: 131 LVRFIKNNHPD-IGVGVAGFPEGHPE 155
[228][TOP]
>UniRef100_A4JAE7 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
vietnamiensis G4 RepID=A4JAE7_BURVG
Length = 276
Score = 115 bits (287), Expect = 2e-24
Identities = 61/145 (42%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQS 143
[229][TOP]
>UniRef100_A0K3F1 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia
cenocepacia RepID=A0K3F1_BURCH
Length = 276
Score = 115 bits (287), Expect = 2e-24
Identities = 61/145 (42%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQS 143
[230][TOP]
>UniRef100_A2VU73 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia PC184 RepID=A2VU73_9BURK
Length = 276
Score = 115 bits (287), Expect = 2e-24
Identities = 61/145 (42%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQS 143
[231][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 114 bits (286), Expect = 3e-24
Identities = 58/146 (39%), Positives = 86/146 (58%)
Frame = +3
Query: 57 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 236
+P+ FSFEFFPP+T++G NLL+ ++ + P F +T GAGGST T+++ +++
Sbjct: 8 NPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRIK 67
Query: 237 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 416
G+E M HLTC ++ LE + + + NVL LRGDPP GQ F GGF A
Sbjct: 68 QEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTVFEPAPGGFRYA 127
Query: 417 RDLVKHIRAKHGDYFGITIAGYPEAH 494
++V+ IR + + F + A YPE H
Sbjct: 128 SEMVRFIREEDFN-FCLGGACYPEGH 152
[232][TOP]
>UniRef100_UPI00016AF3CB 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis MSMB43 RepID=UPI00016AF3CB
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 61/147 (41%), Positives = 84/147 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + SFEFFPPKT +GV L ++ P F +T+GAGGST TLD MQ
Sbjct: 2 NPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK- 60
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E HL+C + + L+ +S+G+++++ALRGD P G + G A +
Sbjct: 61 AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASE 116
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+HGD+F I +A YPE HP A
Sbjct: 117 LVSFIRAEHGDWFRIEVAAYPEYHPQA 143
[233][TOP]
>UniRef100_Q2STU2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis E264 RepID=Q2STU2_BURTA
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 61/147 (41%), Positives = 84/147 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + SFEFFPPKT +GV L ++ P F +T+GAGGST TLD MQ
Sbjct: 2 NPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK- 60
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E HL+C + + L+ +S+G+++++ALRGD P G + G A +
Sbjct: 61 AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASE 116
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+HGD+F I +A YPE HP A
Sbjct: 117 LVSFIRAEHGDWFRIEVAAYPEYHPQA 143
[234][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 114 bits (285), Expect = 4e-24
Identities = 60/144 (41%), Positives = 83/144 (57%)
Frame = +3
Query: 72 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 251
VFSFEFFPPKT++G L + + + P F +T+GAGGST TLD ++Q
Sbjct: 10 VFSFEFFPPKTDEGAEKLRKAREALAELKPKFFSVTYGAGGSTQARTLDTVLEIQRDARF 69
Query: 252 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVK 431
E HL+C E I + LE ++NG+++++ALRGD P G G A +LV+
Sbjct: 70 EAAPHLSCIGSTREHIREILELYRNNGIRHIVALRGDMPSGMR---GEPGELRYANELVE 126
Query: 432 HIRAKHGDYFGITIAGYPEAHPDA 503
IR + GD+F I +A YPE HP A
Sbjct: 127 FIRQETGDHFFIEVAAYPEMHPQA 150
[235][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 114 bits (285), Expect = 4e-24
Identities = 60/142 (42%), Positives = 81/142 (57%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
SFEFFP KTE+G L D++ P F +T+GAGGST D T+D+ KM N +GV T
Sbjct: 7 SFEFFPTKTEEGTKKLYATRDKLAELKPDFFSVTFGAGGSTRDHTMDVVTKM-NGMGVGT 65
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
HL+C ++I L T N ++ ++ALRGD P G G A +LV+ I
Sbjct: 66 APHLSCIGQSKDEIKQLLSTYADNKVERIVALRGDLPSG---MAVSSGELKYANELVELI 122
Query: 438 RAKHGDYFGITIAGYPEAHPDA 503
+ +HGD F + +A YPE HP A
Sbjct: 123 KQEHGDQFHLEVAAYPEMHPQA 144
[236][TOP]
>UniRef100_C4KXI8 Methylenetetrahydrofolate reductase n=23 Tax=pseudomallei group
RepID=C4KXI8_BURPS
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 61/147 (41%), Positives = 84/147 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + SFEFFPPKT +GV L ++ P F +T+GAGGST TLD MQ
Sbjct: 2 NPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK- 60
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E HL+C + + L+ +S+G+++++ALRGD P G + G A +
Sbjct: 61 AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASE 116
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+HGD+F I +A YPE HP A
Sbjct: 117 LVSFIRAEHGDWFRIEVAAYPEYHPQA 143
[237][TOP]
>UniRef100_A4LN89 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei 305 RepID=A4LN89_BURPS
Length = 276
Score = 114 bits (285), Expect = 4e-24
Identities = 61/147 (41%), Positives = 84/147 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + SFEFFPPKT +GV L ++ P F +T+GAGGST TLD MQ
Sbjct: 2 NPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK- 60
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E HL+C + + L+ +S+G+++++ALRGD P G + G A +
Sbjct: 61 AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASE 116
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+HGD+F I +A YPE HP A
Sbjct: 117 LVSFIRAEHGDWFRIEVAAYPEYHPQA 143
[238][TOP]
>UniRef100_UPI0001744B57 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B57
Length = 300
Score = 114 bits (284), Expect = 5e-24
Identities = 61/145 (42%), Positives = 84/145 (57%), Gaps = 4/145 (2%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT + L E + + A P F +T+GAGG+T ++T D+ +++ T ++
Sbjct: 14 FSFEFFPPKTAETSQALYETISELEAFKPDFVSVTYGAGGTTRELTHDLVVRIKQTTSLD 73
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
+ HLTC E I LE G+ N+LAL GDPP G + + + F A DLV+
Sbjct: 74 PIPHLTCVCHSEEDIGGILERYAEAGVSNILALGGDPPRGLANYEKAKDAFQHASDLVRF 133
Query: 435 IR--AKHGDY--FGITIAGYPEAHP 497
IR + H D FGI IAG+PE HP
Sbjct: 134 IRNFSGHPDNRGFGIGIAGFPEGHP 158
[239][TOP]
>UniRef100_UPI00016A5F77 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
oklahomensis EO147 RepID=UPI00016A5F77
Length = 276
Score = 114 bits (284), Expect = 5e-24
Identities = 61/147 (41%), Positives = 84/147 (57%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + SFEFFPPKT +GV L ++ P F +T+GAGGST TLD MQ
Sbjct: 2 NPIELSFEFFPPKTVEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK- 60
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G+E HL+C + + L+ +S+G+++++ALRGD P G + G A +
Sbjct: 61 AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASE 116
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+HGD+F I +A YPE HP A
Sbjct: 117 LVSFIRAEHGDWFRIEVAAYPEYHPQA 143
[240][TOP]
>UniRef100_UPI00016A554F 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
ubonensis Bu RepID=UPI00016A554F
Length = 276
Score = 114 bits (284), Expect = 5e-24
Identities = 60/145 (41%), Positives = 85/145 (58%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT +GV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
+E HL+C + + L+ +S+G+++++ALRGD P G + G A +LV
Sbjct: 63 LEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP +
Sbjct: 119 SFIRAEHGDWFRIEVAGYPEYHPQS 143
[241][TOP]
>UniRef100_B3E425 Methylenetetrahydrofolate reductase n=1 Tax=Geobacter lovleyi SZ
RepID=B3E425_GEOLS
Length = 290
Score = 114 bits (284), Expect = 5e-24
Identities = 57/143 (39%), Positives = 81/143 (56%)
Frame = +3
Query: 78 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 257
S E+FPPK + ++R+ + +P F +T+GAGGS D TL+I +MQ +G+ET
Sbjct: 15 SVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATLEIVTQMQQQLGLET 74
Query: 258 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHI 437
M HLTC +++ L+ + G+QN+LALRGDPP E F A DLV +
Sbjct: 75 MAHLTCVGAQAGRLNRFLDDLSKVGIQNILALRGDPPLETPVEQLTESPFHFASDLVSFV 134
Query: 438 RAKHGDYFGITIAGYPEAHPDAI 506
H G+ +A YPE HP+AI
Sbjct: 135 SQSH-PQMGVAVAAYPETHPEAI 156
[242][TOP]
>UniRef100_B2ZZ98 Methylenetetrahydrofolate reductase n=1 Tax=Methylophilus
methylotrophus RepID=B2ZZ98_METME
Length = 275
Score = 114 bits (284), Expect = 5e-24
Identities = 58/147 (39%), Positives = 89/147 (60%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
N + +SFEFFPPKT +G+ NL + + A SP F +T+GAGGST D T++ ++Q
Sbjct: 3 NNISYSFEFFPPKTVEGMANLRNVRNELAAFSPEFFSVTFGAGGSTRDRTMESVLEIQ-A 61
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
G H++C + E+I + L+ ++ G++ ++ LRGD P G+ G F A +
Sbjct: 62 EGHGAAPHISCISSSKEEIRELLQAYQAKGIKRLVTLRGDIPSGEVS----AGDFKYANE 117
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV IRA+ GD+F + +A YPE HP+A
Sbjct: 118 LVSFIRAETGDWFHLEVAAYPEFHPEA 144
[243][TOP]
>UniRef100_A4BD39 Methylenetetrahydrofolate reductase n=1 Tax=Reinekea blandensis
MED297 RepID=A4BD39_9GAMM
Length = 277
Score = 114 bits (284), Expect = 5e-24
Identities = 62/145 (42%), Positives = 83/145 (57%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
V SFEFFPPKT+ G NLL+ D + +P F +T+GAGGST + T++ ++ N G
Sbjct: 5 VPVSFEFFPPKTDAGYDNLLKAHDELKTTNPEFFSVTYGAGGSTQERTINTVIEL-NKRG 63
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
V HL+C + I D L T K+ G+ ++ALRGD P G V G F A DLV
Sbjct: 64 VPAAPHLSCIGSKADTIKDLLTTYKAEGINRIVALRGDLPSG---MVGTGGDFNYASDLV 120
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
++ + GD F I +A YPE HP A
Sbjct: 121 TFVKQEFGDTFHIEVAAYPEMHPQA 145
[244][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 113 bits (283), Expect = 7e-24
Identities = 58/143 (40%), Positives = 83/143 (58%)
Frame = +3
Query: 75 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 254
FSFEFFPPKT +G L ++ P + +T+GAGG+T TLD ++Q G+E
Sbjct: 6 FSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQRE-GIE 64
Query: 255 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKH 434
HL+C + I L+T + G+++++ALRGD P G + G F A +LV+
Sbjct: 65 AAPHLSCVGSTRDSIRQILQTYRDGGIRHIVALRGDMPSGMGEI----GEFRYANELVEF 120
Query: 435 IRAKHGDYFGITIAGYPEAHPDA 503
IRA+ GD+F I +A YPE HP A
Sbjct: 121 IRAETGDWFNIEVAAYPEYHPQA 143
[245][TOP]
>UniRef100_C6X8F9 Methylenetetrahydrofolate reductase n=1 Tax=Methylovorus sp. SIP3-4
RepID=C6X8F9_METSD
Length = 281
Score = 113 bits (283), Expect = 7e-24
Identities = 59/149 (39%), Positives = 89/149 (59%)
Frame = +3
Query: 57 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 236
D +++ S EFFPPKTE+G+ L E ++ +P F +T+GAGGST D TLD +Q
Sbjct: 2 DKQELMISVEFFPPKTEEGMAKLREARTQLARLNPKFFSVTFGAGGSTRDRTLDTVLDIQ 61
Query: 237 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACA 416
G E H++C + ++I D L+ + + ++ ++ALRGD P G+ G F A
Sbjct: 62 -AAGFEAAPHISCISSSKQEIRDLLQLYQQHDIKRLVALRGDIPSGEVS----AGDFRYA 116
Query: 417 RDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+LV+ IR + GD+F I +A YPE HP+A
Sbjct: 117 NELVEFIRQETGDHFHIEVAAYPEFHPEA 145
[246][TOP]
>UniRef100_A3ZZ23 Methylenetetrahydrofolate reductase n=1 Tax=Blastopirellula marina
DSM 3645 RepID=A3ZZ23_9PLAN
Length = 293
Score = 113 bits (283), Expect = 7e-24
Identities = 58/148 (39%), Positives = 87/148 (58%)
Frame = +3
Query: 60 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 239
P ++ SFE FPPKT+ G +L+ ++++V P + T+GAGGST TLDI +K++
Sbjct: 9 PGRLGLSFELFPPKTDKGDASLMLHVEKLVKFKPDYITCTYGAGGSTRGKTLDIVEKVKQ 68
Query: 240 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACAR 419
GV HLT + V + L + G+ ++ALRGDPP GQ KF G + A
Sbjct: 69 VFGVPVASHLTLVDSTVGDLRLYLAEAERRGVDYIVALRGDPPQGQTKFRPTAKGLSYAS 128
Query: 420 DLVKHIRAKHGDYFGITIAGYPEAHPDA 503
+LV+ I+ + + FG+ +AGYPE H +A
Sbjct: 129 ELVELIKDEFQE-FGVAVAGYPEKHQEA 155
[247][TOP]
>UniRef100_A5WDX3 Methylenetetrahydrofolate reductase n=1 Tax=Psychrobacter sp.
PRwf-1 RepID=A5WDX3_PSYWF
Length = 287
Score = 113 bits (282), Expect = 8e-24
Identities = 61/147 (41%), Positives = 83/147 (56%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 242
NK FSFEFFP KT +GV L + D + +PS+ +T+GAGG+T + TL I + +QN
Sbjct: 2 NKPRFSFEFFPTKTSEGVEKLCQTFDALNELAPSYFSVTYGAGGTTRNRTLGIVETLQNR 61
Query: 243 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARD 422
H++C +I + L+ KS G+ ++ALRGD P GQ G A D
Sbjct: 62 ANTPIAPHISCIGDDKVQISELLDFYKSIGINRMVALRGDLPSGQVGM----GELPFAVD 117
Query: 423 LVKHIRAKHGDYFGITIAGYPEAHPDA 503
LV+HIR D+F I +A YPE HP A
Sbjct: 118 LVRHIREHSADHFHIEVAAYPEMHPQA 144
[248][TOP]
>UniRef100_Q0YRM1 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YRM1_9CHLB
Length = 328
Score = 113 bits (282), Expect = 8e-24
Identities = 60/159 (37%), Positives = 91/159 (57%)
Frame = +3
Query: 24 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 203
++++I +AA K VFSFEFFPPK ++ L + + + +PS+ +T+GAGGST
Sbjct: 41 LVKEILDAAV----KPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTR 96
Query: 204 DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK 383
T D+ K+Q G+ + HLTC E+ L+ + NG+ NVLALRGD P G
Sbjct: 97 SRTHDLVTKIQRETGLTVVSHLTCICSDREETGSILQNYRDNGINNVLALRGDKPAGTAT 156
Query: 384 FVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPD 500
+ F A DL++ I+ + D G+ +AG+PE HP+
Sbjct: 157 LAEAIKDFPHAIDLIRFIKTNYPD-IGVGVAGFPEGHPE 194
[249][TOP]
>UniRef100_C0N2W6 Methylenetetrahydrofolate reductase n=1 Tax=Methylophaga
thiooxidans DMS010 RepID=C0N2W6_9GAMM
Length = 300
Score = 113 bits (282), Expect = 8e-24
Identities = 59/150 (39%), Positives = 85/150 (56%), Gaps = 3/150 (2%)
Frame = +3
Query: 63 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA---KKM 233
N + S EFFPPKTE G+ NL + + +P F +T+GAGGST D TL+ +K
Sbjct: 19 NNLTISCEFFPPKTEKGIANLRRVREELRPLAPEFYSVTFGAGGSTQDNTLEAVIDIQKQ 78
Query: 234 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFAC 413
Q ++ HL+C +++ L T + N ++ V+ALRGD P G ++ G F
Sbjct: 79 QPETDIDAAPHLSCVGSNADRLRTILNTYRDNNIRRVVALRGDLPSG----MRDPGDFRY 134
Query: 414 ARDLVKHIRAKHGDYFGITIAGYPEAHPDA 503
A +LV+ IR + GD+F I +A YPE HP A
Sbjct: 135 ANELVEFIRNETGDFFNIEVAAYPEVHPQA 164
[250][TOP]
>UniRef100_A9AD52 Methylenetetrahydrofolate reductase n=4 Tax=Burkholderia
multivorans RepID=A9AD52_BURM1
Length = 276
Score = 113 bits (282), Expect = 8e-24
Identities = 61/145 (42%), Positives = 83/145 (57%)
Frame = +3
Query: 69 VVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 248
+ SFEFFPPKT DGV L +++ P F +T+GAGGST TLD MQ G
Sbjct: 4 IELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQKD-G 62
Query: 249 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLV 428
++ HL+C + + L+ +S G+++++ALRGD P G G A +LV
Sbjct: 63 LDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSV----GELRYASELV 118
Query: 429 KHIRAKHGDYFGITIAGYPEAHPDA 503
IRA+HGD+F I +AGYPE HP A
Sbjct: 119 SFIRAEHGDWFHIEVAGYPEYHPQA 143