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[1][TOP]
>UniRef100_A7QPC0 Chromosome chr18 scaffold_137, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QPC0_VITVI
Length = 1263
Score = 249 bits (635), Expect(2) = 2e-67
Identities = 111/135 (82%), Positives = 126/135 (93%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
SDSLLNEI++ASL+PE+SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP+DQPPC
Sbjct: 897 SDSLLNEIARASLIPESSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPNDQPPC 956
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
CA ED SC ++G CKDCTTCFRHSDL NDR ST QFR+KLPWFL+ALPSADC+KGGHGAY
Sbjct: 957 CASEDGSCYLNGLCKDCTTCFRHSDLYNDRPSTAQFREKLPWFLAALPSADCSKGGHGAY 1016
Query: 74 TSSVDLKGYDSALFK 30
TSSV+LKG++S + +
Sbjct: 1017 TSSVELKGFESGIIQ 1031
Score = 30.8 bits (68), Expect(2) = 2e-67
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 1029 IIQASSFRTYHTP 1041
[2][TOP]
>UniRef100_B9SMD3 Putative uncharacterized protein n=1 Tax=Ricinus communis
RepID=B9SMD3_RICCO
Length = 584
Score = 244 bits (623), Expect(2) = 5e-65
Identities = 108/135 (80%), Positives = 124/135 (91%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEIS+A+ VPE+SYIAKPAASWLDDFLVWISPEAFGCCRKF NG+YCPPDDQPPC
Sbjct: 218 SNSLLNEISRAASVPESSYIAKPAASWLDDFLVWISPEAFGCCRKFLNGTYCPPDDQPPC 277
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+P++ +C V G CKDCTTCFRHSDL NDR ST+QFR+KLPWFL+ALPSADCAKGGHGAY
Sbjct: 278 CSPDEGTCGVGGVCKDCTTCFRHSDLVNDRPSTVQFREKLPWFLNALPSADCAKGGHGAY 337
Query: 74 TSSVDLKGYDSALFK 30
T+SVDL GY+S + +
Sbjct: 338 TNSVDLNGYESGVIR 352
Score = 27.3 bits (59), Expect(2) = 5e-65
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+I+AS FRTYHTP
Sbjct: 350 VIRASEFRTYHTP 362
[3][TOP]
>UniRef100_UPI0001982F17 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001982F17
Length = 1345
Score = 242 bits (618), Expect(2) = 7e-65
Identities = 108/135 (80%), Positives = 123/135 (91%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEIS+ASLVPE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSYCPPDDQPPC
Sbjct: 978 SNSLLNEISRASLVPESSYIAKPAASWLDDFLVWMSPEAFGCCRKFVNGSYCPPDDQPPC 1037
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+P++ C + G CKDCTTCFRHSDL + R ST QFR+KLPWFL+ALPSADCAKGGHGAY
Sbjct: 1038 CSPDEGYCDLGGVCKDCTTCFRHSDLNSGRPSTEQFREKLPWFLNALPSADCAKGGHGAY 1097
Query: 74 TSSVDLKGYDSALFK 30
TSSVDL GY+S++ +
Sbjct: 1098 TSSVDLNGYESSVIQ 1112
Score = 28.9 bits (63), Expect(2) = 7e-65
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQAS FRTYHTP
Sbjct: 1110 VIQASEFRTYHTP 1122
[4][TOP]
>UniRef100_A7P8Q4 Chromosome chr3 scaffold_8, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7P8Q4_VITVI
Length = 1217
Score = 242 bits (618), Expect(2) = 7e-65
Identities = 108/135 (80%), Positives = 123/135 (91%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEIS+ASLVPE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSYCPPDDQPPC
Sbjct: 850 SNSLLNEISRASLVPESSYIAKPAASWLDDFLVWMSPEAFGCCRKFVNGSYCPPDDQPPC 909
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+P++ C + G CKDCTTCFRHSDL + R ST QFR+KLPWFL+ALPSADCAKGGHGAY
Sbjct: 910 CSPDEGYCDLGGVCKDCTTCFRHSDLNSGRPSTEQFREKLPWFLNALPSADCAKGGHGAY 969
Query: 74 TSSVDLKGYDSALFK 30
TSSVDL GY+S++ +
Sbjct: 970 TSSVDLNGYESSVIQ 984
Score = 28.9 bits (63), Expect(2) = 7e-65
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQAS FRTYHTP
Sbjct: 982 VIQASEFRTYHTP 994
[5][TOP]
>UniRef100_B9HPX9 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9HPX9_POPTR
Length = 1223
Score = 243 bits (621), Expect(2) = 9e-65
Identities = 107/135 (79%), Positives = 123/135 (91%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNE+S+ASLVPE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NG+YCPPDDQPPC
Sbjct: 867 SNSLLNEVSRASLVPESSYIAKPAASWLDDFLVWLSPEAFGCCRKFMNGTYCPPDDQPPC 926
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+P++ SC G CKDCTTCFRHSDL NDR ST+QFR+KLPWFL ALPS+DCAKGGHGAY
Sbjct: 927 CSPDEFSCGFGGVCKDCTTCFRHSDLVNDRPSTVQFREKLPWFLDALPSSDCAKGGHGAY 986
Query: 74 TSSVDLKGYDSALFK 30
TSSVDL GY++ + +
Sbjct: 987 TSSVDLNGYENGVIR 1001
Score = 27.3 bits (59), Expect(2) = 9e-65
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+I+AS FRTYHTP
Sbjct: 999 VIRASEFRTYHTP 1011
[6][TOP]
>UniRef100_UPI0001A7B126 hedgehog receptor n=1 Tax=Arabidopsis thaliana RepID=UPI0001A7B126
Length = 1234
Score = 240 bits (612), Expect(2) = 3e-64
Identities = 108/135 (80%), Positives = 120/135 (88%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEIS+AS +TSYIAKPAASWLDDFLVW+SPEAFGCCRKFTNGSYCPPDDQPPC
Sbjct: 867 SNSLLNEISRASQASDTSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGSYCPPDDQPPC 926
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C E+D C + G CKDCTTCFRHSDL DR ST QFR+KLPWFL+ALPSADCAKGGHGAY
Sbjct: 927 CTAEEDICSLDGICKDCTTCFRHSDLVQDRPSTAQFREKLPWFLNALPSADCAKGGHGAY 986
Query: 74 TSSVDLKGYDSALFK 30
T+SVDLKGY+S + +
Sbjct: 987 TNSVDLKGYESGVIQ 1001
Score = 28.9 bits (63), Expect(2) = 3e-64
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQAS FRTYHTP
Sbjct: 999 VIQASEFRTYHTP 1011
[7][TOP]
>UniRef100_UPI000034F451 patched family protein n=1 Tax=Arabidopsis thaliana
RepID=UPI000034F451
Length = 1272
Score = 231 bits (589), Expect(2) = 4e-62
Identities = 102/134 (76%), Positives = 119/134 (88%), Gaps = 1/134 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
+SLLNEI++ASL PE SYIAKPAASWLDDFLVW+SPEAFGCCRKFTNG++CPPDDQPPCC
Sbjct: 896 NSLLNEIARASLTPELSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGTFCPPDDQPPCC 955
Query: 248 APEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
P SC +S CKDCTTCFRH+DL +DR ST QF++KLPWFL+ALPSADCAKGGHGAY+
Sbjct: 956 PPGQTSCGLSEVCKDCTTCFRHADLSSDRPSTTQFKEKLPWFLNALPSADCAKGGHGAYS 1015
Query: 71 SSVDLKGYDSALFK 30
SSVDL+GY + + +
Sbjct: 1016 SSVDLQGYANGIIQ 1029
Score = 30.8 bits (68), Expect(2) = 4e-62
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 1027 IIQASSFRTYHTP 1039
[8][TOP]
>UniRef100_Q9C8F0 Putative uncharacterized protein T8D8.3 (Fragment) n=1
Tax=Arabidopsis thaliana RepID=Q9C8F0_ARATH
Length = 524
Score = 231 bits (589), Expect(2) = 4e-62
Identities = 102/134 (76%), Positives = 119/134 (88%), Gaps = 1/134 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
+SLLNEI++ASL PE SYIAKPAASWLDDFLVW+SPEAFGCCRKFTNG++CPPDDQPPCC
Sbjct: 133 NSLLNEIARASLTPELSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGTFCPPDDQPPCC 192
Query: 248 APEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
P SC +S CKDCTTCFRH+DL +DR ST QF++KLPWFL+ALPSADCAKGGHGAY+
Sbjct: 193 PPGQTSCGLSEVCKDCTTCFRHADLSSDRPSTTQFKEKLPWFLNALPSADCAKGGHGAYS 252
Query: 71 SSVDLKGYDSALFK 30
SSVDL+GY + + +
Sbjct: 253 SSVDLQGYANGIIQ 266
Score = 30.8 bits (68), Expect(2) = 4e-62
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 264 IIQASSFRTYHTP 276
[9][TOP]
>UniRef100_A5BXT3 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BXT3_VITVI
Length = 692
Score = 232 bits (592), Expect(2) = 7e-62
Identities = 102/129 (79%), Positives = 117/129 (90%), Gaps = 1/129 (0%)
Frame = -2
Query: 413 EISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCAPEDD 234
+IS+ASLVPE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSYCPPDDQPPCC+P++
Sbjct: 328 QISRASLVPESSYIAKPAASWLDDFLVWMSPEAFGCCRKFVNGSYCPPDDQPPCCSPDEG 387
Query: 233 SC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSSVDL 57
C + G CKDCTTCFRHSDL + R ST QFR+KLPWFL+ALPSADCAKGGHGAYTSSVDL
Sbjct: 388 YCDLGGVCKDCTTCFRHSDLNSGRPSTEQFREKLPWFLNALPSADCAKGGHGAYTSSVDL 447
Query: 56 KGYDSALFK 30
GY+S++ +
Sbjct: 448 NGYESSVIQ 456
Score = 28.9 bits (63), Expect(2) = 7e-62
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQAS FRTYHTP
Sbjct: 454 VIQASEFRTYHTP 466
[10][TOP]
>UniRef100_B9H5I2 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9H5I2_POPTR
Length = 1274
Score = 229 bits (585), Expect(2) = 2e-61
Identities = 103/135 (76%), Positives = 119/135 (88%), Gaps = 1/135 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S SLLNEI++ASL PE++YIA PAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQ PC
Sbjct: 898 SKSLLNEIARASLTPESTYIAMPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQFPC 957
Query: 251 CAPEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+ + SC + G CKDCTTCFRHSDL NDR ST QF++KLP FL+ALPSADCAKGGHGAY
Sbjct: 958 CSSDTGSCGLGGVCKDCTTCFRHSDLNNDRPSTSQFKEKLPLFLNALPSADCAKGGHGAY 1017
Query: 74 TSSVDLKGYDSALFK 30
TSS+DL+GY++ + +
Sbjct: 1018 TSSIDLQGYENGVIQ 1032
Score = 30.4 bits (67), Expect(2) = 2e-61
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQASSFRTYHTP
Sbjct: 1030 VIQASSFRTYHTP 1042
[11][TOP]
>UniRef100_B9R8N7 Hedgehog receptor, putative n=1 Tax=Ricinus communis
RepID=B9R8N7_RICCO
Length = 1235
Score = 227 bits (579), Expect(2) = 4e-60
Identities = 105/134 (78%), Positives = 115/134 (85%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
SDSLLNEI++ASL P++SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC
Sbjct: 877 SDSLLNEIARASLTPKSSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 936
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
V G CKDCTTCFRHSD NDR ST QFRDKLP FL+ALPSADCAKGGHGAYT
Sbjct: 937 -------DVGGVCKDCTTCFRHSDFNNDRPSTTQFRDKLPLFLNALPSADCAKGGHGAYT 989
Query: 71 SSVDLKGYDSALFK 30
SSV+L+GY+ + +
Sbjct: 990 SSVELEGYEKGVIQ 1003
Score = 28.1 bits (61), Expect(2) = 4e-60
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQASSFRTYH P
Sbjct: 1001 VIQASSFRTYHMP 1013
[12][TOP]
>UniRef100_Q01KH5 H0409D10.4 protein n=1 Tax=Oryza sativa RepID=Q01KH5_ORYSA
Length = 1372
Score = 218 bits (554), Expect(2) = 1e-57
Identities = 97/137 (70%), Positives = 114/137 (83%), Gaps = 3/137 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEI+K SL PETSYIAKPAASWLDDFL+W+SPEAFGCCRKF NGSYCPPDDQPPC
Sbjct: 905 SNSLLNEIAKQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVNGSYCPPDDQPPC 964
Query: 251 CAPEDDS---CVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
C + DS SGAC +CTTCF SDL N R ST QF++KLPWFL ALPS+DC+KGG G
Sbjct: 965 CQHDQDSISCSASGACNNCTTCFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKG 1024
Query: 80 AYTSSVDLKGYDSALFK 30
AY++S+DL GY++ + +
Sbjct: 1025 AYSTSLDLNGYENGIIQ 1041
Score = 29.6 bits (65), Expect(2) = 1e-57
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 1039 IIQASAFRTYHTP 1051
[13][TOP]
>UniRef100_Q7XUB7 OSJNBb0078D11.11 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q7XUB7_ORYSJ
Length = 1361
Score = 218 bits (554), Expect(2) = 1e-57
Identities = 97/137 (70%), Positives = 114/137 (83%), Gaps = 3/137 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEI+K SL PETSYIAKPAASWLDDFL+W+SPEAFGCCRKF NGSYCPPDDQPPC
Sbjct: 905 SNSLLNEIAKQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVNGSYCPPDDQPPC 964
Query: 251 CAPEDDS---CVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
C + DS SGAC +CTTCF SDL N R ST QF++KLPWFL ALPS+DC+KGG G
Sbjct: 965 CQHDQDSSSCSASGACNNCTTCFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKG 1024
Query: 80 AYTSSVDLKGYDSALFK 30
AY++S+DL GY++ + +
Sbjct: 1025 AYSTSLDLNGYENGIIQ 1041
Score = 29.6 bits (65), Expect(2) = 1e-57
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 1039 IIQASAFRTYHTP 1051
[14][TOP]
>UniRef100_B9FBZ9 Putative uncharacterized protein n=1 Tax=Oryza sativa Japonica Group
RepID=B9FBZ9_ORYSJ
Length = 1211
Score = 218 bits (554), Expect(2) = 1e-57
Identities = 97/137 (70%), Positives = 114/137 (83%), Gaps = 3/137 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEI+K SL PETSYIAKPAASWLDDFL+W+SPEAFGCCRKF NGSYCPPDDQPPC
Sbjct: 845 SNSLLNEIAKQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVNGSYCPPDDQPPC 904
Query: 251 CAPEDDS---CVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
C + DS SGAC +CTTCF SDL N R ST QF++KLPWFL ALPS+DC+KGG G
Sbjct: 905 CQHDQDSSSCSASGACNNCTTCFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKG 964
Query: 80 AYTSSVDLKGYDSALFK 30
AY++S+DL GY++ + +
Sbjct: 965 AYSTSLDLNGYENGIIQ 981
Score = 29.6 bits (65), Expect(2) = 1e-57
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 979 IIQASAFRTYHTP 991
[15][TOP]
>UniRef100_A9SMZ7 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9SMZ7_PHYPA
Length = 1170
Score = 209 bits (531), Expect = 1e-52
Identities = 96/142 (67%), Positives = 114/142 (80%), Gaps = 3/142 (2%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSLLNE+++A+L PETSYI++PAASWLDDFLVW+SP AFGCCRKF G+YCPPDDQPPCC
Sbjct: 891 DSLLNEVTRAALSPETSYISRPAASWLDDFLVWLSPNAFGCCRKFPEGNYCPPDDQPPCC 950
Query: 248 APEDDSCVSG-ACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
PE + C G C +CTTCF SDL R ST QF+ KLPWFL+ALPSADCAKGGHGAYT
Sbjct: 951 -PEGEECGFGDTCSECTTCFLQSDLLEGRPSTEQFQAKLPWFLAALPSADCAKGGHGAYT 1009
Query: 71 SSVDLKGYDSALFK--HHRSVH 12
+S++L GY+S + + RS H
Sbjct: 1010 TSLNLTGYESGVIRASEFRSYH 1031
[16][TOP]
>UniRef100_A5APM6 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5APM6_VITVI
Length = 1050
Score = 189 bits (481), Expect(2) = 1e-49
Identities = 91/133 (68%), Positives = 105/133 (78%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS L +I++ASL+PE+SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP+DQ
Sbjct: 735 DSYL-QIARASLIPESSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPNDQ---- 789
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
CFRHSDL NDR ST QFR+KLPWFL+ALPSADC+KGGHGAYTS
Sbjct: 790 -----------------CFRHSDLYNDRPSTAQFREKLPWFLAALPSADCSKGGHGAYTS 832
Query: 68 SVDLKGYDSALFK 30
SV+LKG++S + +
Sbjct: 833 SVELKGFESGIIQ 845
Score = 30.8 bits (68), Expect(2) = 1e-49
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 843 IIQASSFRTYHTP 855
[17][TOP]
>UniRef100_UPI0001985140 PREDICTED: similar to patched family protein n=1 Tax=Vitis vinifera
RepID=UPI0001985140
Length = 1018
Score = 189 bits (480), Expect(2) = 1e-49
Identities = 89/132 (67%), Positives = 104/132 (78%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
+L + I++ASL+PE+SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP+DQ
Sbjct: 736 ALASIIARASLIPESSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPNDQ----- 790
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSS 66
CFRHSDL NDR ST QFR+KLPWFL+ALPSADC+KGGHGAYTSS
Sbjct: 791 ----------------CFRHSDLYNDRPSTAQFREKLPWFLAALPSADCSKGGHGAYTSS 834
Query: 65 VDLKGYDSALFK 30
V+LKG++S + +
Sbjct: 835 VELKGFESGIIQ 846
Score = 30.8 bits (68), Expect(2) = 1e-49
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 844 IIQASSFRTYHTP 856
[18][TOP]
>UniRef100_Q9SVF0 Putative uncharacterized protein AT4g38350 n=1 Tax=Arabidopsis
thaliana RepID=Q9SVF0_ARATH
Length = 1055
Score = 185 bits (470), Expect(2) = 8e-48
Identities = 89/132 (67%), Positives = 100/132 (75%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
+L + IS+AS +TSYIAKPAASWLDDFLVW+SPEAFGCCRKFTNGSYCPPDDQ
Sbjct: 771 ALASIISRASQASDTSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGSYCPPDDQ----- 825
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSS 66
CFRHSDL DR ST QFR+KLPWFL+ALPSADCAKGGHGAYT+S
Sbjct: 826 ----------------CFRHSDLVQDRPSTAQFREKLPWFLNALPSADCAKGGHGAYTNS 869
Query: 65 VDLKGYDSALFK 30
VDLKGY+S + +
Sbjct: 870 VDLKGYESGVIQ 881
Score = 28.9 bits (63), Expect(2) = 8e-48
Identities = 11/13 (84%), Positives = 12/13 (92%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
+IQAS FRTYHTP
Sbjct: 879 VIQASEFRTYHTP 891
[19][TOP]
>UniRef100_C5YE00 Putative uncharacterized protein Sb06g025390 n=1 Tax=Sorghum bicolor
RepID=C5YE00_SORBI
Length = 1232
Score = 184 bits (467), Expect(2) = 1e-47
Identities = 88/134 (65%), Positives = 100/134 (74%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEIS+ SL PETSYIAKPAASWLDDFLVW+SPEAFGCCRKF NG+YCPPDDQ
Sbjct: 913 SNSLLNEISRQSLSPETSYIAKPAASWLDDFLVWMSPEAFGCCRKFVNGNYCPPDDQ--- 969
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
CF HSDL N R ST QFRDKLPWFL ALPS+DC+KGG GAY+
Sbjct: 970 ------------------CFLHSDLDNGRPSTTQFRDKLPWFLDALPSSDCSKGGKGAYS 1011
Query: 71 SSVDLKGYDSALFK 30
+S+DL GY+S + +
Sbjct: 1012 TSLDLSGYESGIIQ 1025
Score = 29.6 bits (65), Expect(2) = 1e-47
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 1023 IIQASAFRTYHTP 1035
[20][TOP]
>UniRef100_Q9SHN9 F7F22.1 n=1 Tax=Arabidopsis thaliana RepID=Q9SHN9_ARATH
Length = 1275
Score = 181 bits (458), Expect(2) = 5e-47
Identities = 86/133 (64%), Positives = 102/133 (76%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS L +I++ASL PE SYIAKPAASWLDDFLVW+SPEAFGCCRKFTNG++CPPDDQ
Sbjct: 927 DSYL-QIARASLTPELSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGTFCPPDDQ---- 981
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
CFRH+DL +DR ST QF++KLPWFL+ALPSADCAKGGHGAY+S
Sbjct: 982 -----------------CFRHADLSSDRPSTTQFKEKLPWFLNALPSADCAKGGHGAYSS 1024
Query: 68 SVDLKGYDSALFK 30
SVDL+GY + + +
Sbjct: 1025 SVDLQGYANGIIQ 1037
Score = 30.8 bits (68), Expect(2) = 5e-47
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQASSFRTYHTP
Sbjct: 1035 IIQASSFRTYHTP 1047
[21][TOP]
>UniRef100_B8AT56 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=B8AT56_ORYSI
Length = 1257
Score = 179 bits (453), Expect(2) = 4e-46
Identities = 84/134 (62%), Positives = 99/134 (73%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S+SLLNEI+K SL PETSYIAKPAASWLDDFL+W+SPEAFGCCRKF NGSYCPPDDQ
Sbjct: 863 SNSLLNEIAKQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVNGSYCPPDDQ--- 919
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
CF SDL N R ST QF++KLPWFL ALPS+DC+KGG GAY+
Sbjct: 920 ------------------CFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKGAYS 961
Query: 71 SSVDLKGYDSALFK 30
+S+DL GY++ + +
Sbjct: 962 TSLDLNGYENGIIQ 975
Score = 29.6 bits (65), Expect(2) = 4e-46
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 973 IIQASAFRTYHTP 985
[22][TOP]
>UniRef100_A9RFW8 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
patens RepID=A9RFW8_PHYPA
Length = 1262
Score = 186 bits (473), Expect = 5e-46
Identities = 89/142 (62%), Positives = 107/142 (75%), Gaps = 3/142 (2%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
+SLLNEIS+A+L P++S+IA+PAASWLDDFL+W+SP AFGCCRKF +G YCPP DQ
Sbjct: 859 NSLLNEISRAALSPQSSFIARPAASWLDDFLIWLSPNAFGCCRKFQDGGYCPPVDQYYTN 918
Query: 248 APEDDSC-VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
C ++ C +CTTCF SDL R ST QFR KLPWFL+ALPSADC+KGGHGAYT
Sbjct: 919 LWSCLQCGLNNTCSECTTCFLQSDLVEGRPSTEQFRSKLPWFLAALPSADCSKGGHGAYT 978
Query: 71 SSVDLKGYDSALFK--HHRSVH 12
+S+DL GYDS + K RS H
Sbjct: 979 NSLDLAGYDSGIIKASEFRSYH 1000
[23][TOP]
>UniRef100_C7J1V6 Os04g0563801 protein n=1 Tax=Oryza sativa Japonica Group
RepID=C7J1V6_ORYSJ
Length = 963
Score = 82.0 bits (201), Expect(2) = 3e-17
Identities = 34/56 (60%), Positives = 45/56 (80%)
Frame = -2
Query: 197 CFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSSVDLKGYDSALFK 30
CF SDL N R ST QF++KLPWFL ALPS+DC+KGG GAY++S+DL GY++ + +
Sbjct: 724 CFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKGAYSTSLDLNGYENGIIQ 779
Score = 29.6 bits (65), Expect(2) = 3e-17
Identities = 12/13 (92%), Positives = 13/13 (100%)
Frame = -1
Query: 39 IIQASSFRTYHTP 1
IIQAS+FRTYHTP
Sbjct: 777 IIQASAFRTYHTP 789
[24][TOP]
>UniRef100_UPI0000E4A87C PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E4A87C
Length = 558
Score = 86.7 bits (213), Expect = 8e-16
Identities = 48/129 (37%), Positives = 68/129 (52%), Gaps = 2/129 (1%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCR-KFTNGSYCPPDDQP 258
+DSL +I ASL+ E +YIA+P +SW+DD+ W+ P+ G CCR + +CP D P
Sbjct: 131 ADSLTQQIYYASLIKEKTYIAQPTSSWMDDYFDWLKPQVSGSCCRVSIPDEEFCPSQDSP 190
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C C S+ RNDR + F + LP FL+ +P+A C KGG A
Sbjct: 191 YTL--------------CRPCIPQSE-RNDRRDPVTFEEFLPDFLTDVPNAVCNKGGSAA 235
Query: 77 YTSSVDLKG 51
Y ++V G
Sbjct: 236 YGNAVQFLG 244
[25][TOP]
>UniRef100_UPI0000E48D84 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48D84
Length = 705
Score = 86.7 bits (213), Expect = 8e-16
Identities = 48/129 (37%), Positives = 68/129 (52%), Gaps = 2/129 (1%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCR-KFTNGSYCPPDDQP 258
+DSL +I ASL+ E +YIA+P +SW+DD+ W+ P+ G CCR + +CP D P
Sbjct: 271 ADSLTQQIYYASLIKEKTYIAQPTSSWMDDYFDWLKPQVSGSCCRVSIPDEEFCPSQDSP 330
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C C S+ RNDR + F + LP FL+ +P+A C KGG A
Sbjct: 331 YTL--------------CRPCIPQSE-RNDRRDPVTFEEFLPDFLTDVPNAVCNKGGSAA 375
Query: 77 YTSSVDLKG 51
Y ++V G
Sbjct: 376 YGNAVQFLG 384
[26][TOP]
>UniRef100_UPI0000E48442 PREDICTED: similar to Niemann Pick type C1 n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48442
Length = 599
Score = 86.7 bits (213), Expect = 8e-16
Identities = 48/129 (37%), Positives = 68/129 (52%), Gaps = 2/129 (1%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCR-KFTNGSYCPPDDQP 258
+DSL +I ASL+ E +YIA+P +SW+DD+ W+ P+ G CCR + +CP D P
Sbjct: 172 ADSLTQQIYYASLIKEKTYIAQPTSSWMDDYFDWLKPQVSGSCCRVSIPDEEFCPSQDSP 231
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C C S+ RNDR + F + LP FL+ +P+A C KGG A
Sbjct: 232 YTL--------------CRPCIPQSE-RNDRRDPVTFEEFLPDFLTDVPNAVCNKGGSAA 276
Query: 77 YTSSVDLKG 51
Y ++V G
Sbjct: 277 YGNAVQFLG 285
[27][TOP]
>UniRef100_UPI0001795FBF PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Equus caballus RepID=UPI0001795FBF
Length = 1329
Score = 84.0 bits (206), Expect = 5e-15
Identities = 53/144 (36%), Positives = 71/144 (49%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDD 264
S SL +I A+ PE SY+A PA+SW+DDF+ W++P + CCR +T+G +CP
Sbjct: 926 SYSLTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYTSGPNKDEFCPSTI 983
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C CVS L R S QF LPWFL+ P+ +C KGG
Sbjct: 984 NALACLKY---CVSFT------------LGPIRPSVEQFHKYLPWFLNDPPNTNCPKGGL 1028
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY++SVDL L + H
Sbjct: 1029 AAYSTSVDLGPEGQVLASRFMAYH 1052
[28][TOP]
>UniRef100_A8PPM6 Myosin head containing protein, putative n=1 Tax=Brugia malayi
RepID=A8PPM6_BRUMA
Length = 1548
Score = 82.4 bits (202), Expect = 1e-14
Identities = 53/143 (37%), Positives = 66/143 (46%), Gaps = 3/143 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG---CCRKFTNGSYCPPDDQ 261
+DSL +I+ A+ SYIA PA +WLDD+ W+ P FG CCR F NG++C +
Sbjct: 185 TDSLGAQIAHAARWSNRSYIAYPAMNWLDDYFDWLQP--FGNPPCCRMFPNGTFCSSTEN 242
Query: 260 PPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
C P C F R+D F D L F S PS CAKGGH
Sbjct: 243 SESCIP------------CNVEFFDGRPRSDL-----FYDHLTHFFSNNPSTKCAKGGHA 285
Query: 80 AYTSSVDLKGYDSALFKHHRSVH 12
AY S+V L L H + H
Sbjct: 286 AYGSAVKLSRRGRILSSHFMTYH 308
[29][TOP]
>UniRef100_Q66NT1 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NT1_CIOIN
Length = 371
Score = 81.3 bits (199), Expect = 3e-14
Identities = 45/125 (36%), Positives = 68/125 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYV 142
Query: 71 SSVDL 57
+SV +
Sbjct: 143 TSVQV 147
[30][TOP]
>UniRef100_Q66NR2 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR2_CIOIN
Length = 371
Score = 80.5 bits (197), Expect = 5e-14
Identities = 45/125 (36%), Positives = 68/125 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSVDL 57
+SV +
Sbjct: 143 TSVQV 147
[31][TOP]
>UniRef100_UPI000180B49C PREDICTED: Niemann-Pick disease, type C3 n=1 Tax=Ciona intestinalis
RepID=UPI000180B49C
Length = 1313
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 922 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 975
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 976 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 1029
Query: 71 SSV 63
+SV
Sbjct: 1030 TSV 1032
[32][TOP]
>UniRef100_A0MJA5 Niemann-Pick C1-like 1 protein n=2 Tax=Macaca RepID=A0MJA5_MACMU
Length = 1332
Score = 80.1 bits (196), Expect = 7e-14
Identities = 49/138 (35%), Positives = 72/138 (52%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
S +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + +G P DQ
Sbjct: 929 SFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYISG---PNKDQFCPST 983
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSS 66
+C+ K+C + + + R S QF LPWFL+ P+ C KGG GAY++S
Sbjct: 984 VNSLNCL----KNCLSI----TMGSVRPSVEQFYKYLPWFLNDRPNIKCPKGGLGAYSTS 1035
Query: 65 VDLKGYDSALFKHHRSVH 12
V+L L + H
Sbjct: 1036 VNLTSDGQVLASRFMAYH 1053
[33][TOP]
>UniRef100_Q66NS9 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS9_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[34][TOP]
>UniRef100_Q66NS4 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS4_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[35][TOP]
>UniRef100_Q66NS3 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS3_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[36][TOP]
>UniRef100_Q66NS0 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS0_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[37][TOP]
>UniRef100_Q66NR8 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR8_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[38][TOP]
>UniRef100_Q66NR7 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR7_CIOIN
Length = 371
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 88
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 89 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 142
Query: 71 SSV 63
+SV
Sbjct: 143 TSV 145
[39][TOP]
>UniRef100_Q4H343 Niemann-Pick disease, type C3 (Fragment) n=1 Tax=Ciona intestinalis
RepID=Q4H343_CIOIN
Length = 278
Score = 80.1 bits (196), Expect = 7e-14
Identities = 45/123 (36%), Positives = 67/123 (54%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G ++ C
Sbjct: 60 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTG-----EEDVFC 113
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
A + VS +C C + R + +F LPWFL+ P CAKGGH AY
Sbjct: 114 NA----TVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGHAAYG 167
Query: 71 SSV 63
+SV
Sbjct: 168 TSV 170
[40][TOP]
>UniRef100_Q17FP9 Niemann-pick C1 (Fragment) n=1 Tax=Aedes aegypti RepID=Q17FP9_AEDAE
Length = 1132
Score = 80.1 bits (196), Expect = 7e-14
Identities = 48/125 (38%), Positives = 63/125 (50%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL ++ AS P +YIA+PAASWLDD++ W S + CCR+F NGS+CP D
Sbjct: 624 DSLSTQVYIASKRPTETYIARPAASWLDDYMDW-SAASDSCCRQFGNGSFCPHD------ 676
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
C C + N R + FR + +FL P CAK GH AY +
Sbjct: 677 ------------MTCDKCSINLTSWN-RPTEPSFRRYVSFFLQDNPDPSCAKAGHAAYGN 723
Query: 68 SVDLK 54
V+LK
Sbjct: 724 GVNLK 728
[41][TOP]
>UniRef100_A3KMG9 Npc1l1 protein (Fragment) n=1 Tax=Mus musculus RepID=A3KMG9_MOUSE
Length = 1332
Score = 79.7 bits (195), Expect = 9e-14
Identities = 50/144 (34%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDD 264
S SL +I AS P SY+A A+SW+DDF+ W++P + CCR +T G +CP D
Sbjct: 926 SFSLTQKIQYASEFPNQSYVAIAASSWVDDFIDWLTPSS-SCCRIYTRGPHKDEFCPSTD 984
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C K+C + L R +T QF LPWFL+ P+ C KGG
Sbjct: 985 TSFNC-----------LKNC----MNRTLGPVRPTTEQFHKYLPWFLNDTPNIRCPKGGL 1029
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY +SV+L + + H
Sbjct: 1030 AAYRTSVNLSSDGQIIASQFMAYH 1053
[42][TOP]
>UniRef100_Q66NR4 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR4_CIOIN
Length = 371
Score = 79.7 bits (195), Expect = 9e-14
Identities = 46/127 (36%), Positives = 65/127 (51%), Gaps = 4/127 (3%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ +I++ S +P S+IA PA+SWLDD+ W+ P++ CCR G
Sbjct: 35 NNSLIEQIARMSKMPNYSHIAYPASSWLDDYFDWLKPQS-SCCRHDNTGK---------- 83
Query: 251 CAPEDDSC----VSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
ED C VS +C C + R + +F LPWFL+ P CAKGGH
Sbjct: 84 ---EDVFCNATVVSTSCIACRSA--QESANQSRPTPDEFMKFLPWFLNDNPETKCAKGGH 138
Query: 83 GAYTSSV 63
AY +SV
Sbjct: 139 AAYGTSV 145
[43][TOP]
>UniRef100_Q6T3U4 Niemann-Pick C1-like protein 1 n=1 Tax=Mus musculus RepID=NPCL1_MOUSE
Length = 1333
Score = 79.7 bits (195), Expect = 9e-14
Identities = 50/144 (34%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDD 264
S SL +I AS P SY+A A+SW+DDF+ W++P + CCR +T G +CP D
Sbjct: 927 SFSLTQKIQYASEFPNQSYVAIAASSWVDDFIDWLTPSS-SCCRIYTRGPHKDEFCPSTD 985
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C K+C + L R +T QF LPWFL+ P+ C KGG
Sbjct: 986 TSFNC-----------LKNC----MNRTLGPVRPTTEQFHKYLPWFLNDTPNIRCPKGGL 1030
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY +SV+L + + H
Sbjct: 1031 AAYRTSVNLSSDGQIIASQFMAYH 1054
[44][TOP]
>UniRef100_UPI000069E05C Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05C
Length = 1228
Score = 79.3 bits (194), Expect = 1e-13
Identities = 45/122 (36%), Positives = 65/122 (53%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL +I A+ P+ SY+A PA+SW+DDF+ W++P + CCR NG++ C
Sbjct: 865 DSLTQKIQYATEYPDRSYLAIPASSWVDDFIDWLNPTS-DCCRLLLNGTF---------C 914
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
+ D+ + G + C S R + QF LP FL+ P+ C KGG GAY +
Sbjct: 915 SSTSDTALPGCLRKCMP----STTGALRPNLEQFNTYLPVFLNDYPNLKCPKGGLGAYDN 970
Query: 68 SV 63
SV
Sbjct: 971 SV 972
[45][TOP]
>UniRef100_UPI000069E05B Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05B
Length = 1260
Score = 79.3 bits (194), Expect = 1e-13
Identities = 45/122 (36%), Positives = 65/122 (53%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL +I A+ P+ SY+A PA+SW+DDF+ W++P + CCR NG++ C
Sbjct: 923 DSLTQKIQYATEYPDRSYLAIPASSWVDDFIDWLNPTS-DCCRLLLNGTF---------C 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
+ D+ + G + C S R + QF LP FL+ P+ C KGG GAY +
Sbjct: 973 SSTSDTALPGCLRKCMP----STTGALRPNLEQFNTYLPVFLNDYPNLKCPKGGLGAYDN 1028
Query: 68 SV 63
SV
Sbjct: 1029 SV 1030
[46][TOP]
>UniRef100_B0WCU9 Niemann-pick C1 n=1 Tax=Culex quinquefasciatus RepID=B0WCU9_CULQU
Length = 1645
Score = 79.3 bits (194), Expect = 1e-13
Identities = 50/133 (37%), Positives = 71/133 (53%), Gaps = 1/133 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL +I AS PE +YIA+PA+SWLDD++ W A CC+K T+GS+CP
Sbjct: 1132 DSLSTQIYIASRRPEETYIARPASSWLDDYIDWSG--APTCCKKRTDGSFCPH------- 1182
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
+ +CK C +DL +R + FR + +FL P CAK GH AY +
Sbjct: 1183 -------TTASCKSCQ--MNLTDL--NRPNQTDFRRYVSFFLQDNPDDQCAKAGHAAYAT 1231
Query: 68 SVD-LKGYDSALF 33
V+ L+ +A+F
Sbjct: 1232 GVNILQDKSNAIF 1244
[47][TOP]
>UniRef100_C4Q7T0 Niemann-pick C1 (NPC1) n=1 Tax=Schistosoma mansoni
RepID=C4Q7T0_SCHMA
Length = 950
Score = 79.0 bits (193), Expect = 2e-13
Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCRKFTN-GSYCPPDDQPPC 252
SL+ +IS A+ P S+I PA+SW+DD+ WI P + CCR N +CPPD
Sbjct: 574 SLIGKISAAASYPNRSWIVSPASSWIDDYFDWIDPSSSSLCCRINRNTHKFCPPD----- 628
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
D++C+S C H L + R + + F LP+FLS P ++C KGG AY+
Sbjct: 629 --LIDNNCIS--------CPVH--LNDGRPNALDFSQYLPYFLSENPGSNCPKGGKAAYS 676
Query: 71 SSVDL 57
+ V L
Sbjct: 677 TGVRL 681
[48][TOP]
>UniRef100_A0MJA4 Niemann-Pick C1-like 1 protein n=1 Tax=Canis lupus familiaris
RepID=A0MJA4_CANFA
Length = 1325
Score = 78.6 bits (192), Expect = 2e-13
Identities = 51/144 (35%), Positives = 68/144 (47%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGS----YCPPDD 264
S SL +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + G+ +CP
Sbjct: 927 SYSLTQKIQYATEFPEESYLAIPASSWVDDFIDWLTPSS--CCRLYAFGANKDKFCPSTV 984
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C K+C + L R S QF LPWFLS P+ C KGG
Sbjct: 985 NSLAC-----------LKNCV----NFTLGPVRPSVDQFHKYLPWFLSDPPNIKCPKGGL 1029
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY +SV L L + H
Sbjct: 1030 AAYNTSVHLGSDGQVLASRFMAYH 1053
[49][TOP]
>UniRef100_Q7Q409 AGAP008137-PA n=1 Tax=Anopheles gambiae RepID=Q7Q409_ANOGA
Length = 1192
Score = 78.6 bits (192), Expect = 2e-13
Identities = 46/122 (37%), Positives = 63/122 (51%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL ++ AS P+++Y+A+PA+SWLDD++ W + A GCC+++ NGS+CP Q C
Sbjct: 820 DSLSTQLYIASKQPQSTYLARPASSWLDDYIDWSA--APGCCKQWNNGSFCP--HQKSAC 875
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
GAC T R FR + +FL P CAK GH AY S
Sbjct: 876 ---------GACNISMTA-------QKRPVESSFRQYVSFFLEDNPDEACAKAGHAAYGS 919
Query: 68 SV 63
V
Sbjct: 920 GV 921
[50][TOP]
>UniRef100_Q5C0S9 SJCHGC04467 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5C0S9_SCHJA
Length = 361
Score = 78.2 bits (191), Expect = 3e-13
Identities = 48/125 (38%), Positives = 63/125 (50%), Gaps = 2/125 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCRKFTNGS-YCPPDDQPPC 252
SL+ EIS A++ S+IA PA+SWLDD+ WI P CCR + N S +CPPD
Sbjct: 158 SLIQEISSAAVYANRSWIASPASSWLDDYFDWIDPSGSTLCCRIYQNTSKFCPPDSTD-- 215
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+CT C + D N R + + F LP FL P ++C KGG AY+
Sbjct: 216 -------------ANCTQCPVYLD--NGRPNPIDFYYYLPQFLHENPGSNCPKGGKAAYS 260
Query: 71 SSVDL 57
V L
Sbjct: 261 VGVRL 265
[51][TOP]
>UniRef100_Q17RV5 NPC1-like 1 protein n=2 Tax=Homo sapiens RepID=Q17RV5_HUMAN
Length = 1332
Score = 78.2 bits (191), Expect = 3e-13
Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
S +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + +G +CP
Sbjct: 929 SFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYISGPNKDKFCPSTVNS 986
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C S G+ R S QF LPWFL+ P+ C KGG A
Sbjct: 987 LNCLKNCMSITMGSV---------------RPSVEQFHKYLPWFLNDRPNIKCPKGGLAA 1031
Query: 77 YTSSVDLKGYDSALFKHHRSVH 12
Y++SV+L L + H
Sbjct: 1032 YSTSVNLTSDGQVLASRFMAYH 1053
[52][TOP]
>UniRef100_B7ZLE6 NPC1L1 protein n=1 Tax=Homo sapiens RepID=B7ZLE6_HUMAN
Length = 1286
Score = 78.2 bits (191), Expect = 3e-13
Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
S +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + +G +CP
Sbjct: 883 SFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYISGPNKDKFCPSTVNS 940
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C S G+ R S QF LPWFL+ P+ C KGG A
Sbjct: 941 LNCLKNCMSITMGSV---------------RPSVEQFHKYLPWFLNDRPNIKCPKGGLAA 985
Query: 77 YTSSVDLKGYDSALFKHHRSVH 12
Y++SV+L L + H
Sbjct: 986 YSTSVNLTSDGQVLASRFMAYH 1007
[53][TOP]
>UniRef100_B0X6W3 Niemann-Pick C1 protein n=1 Tax=Culex quinquefasciatus
RepID=B0X6W3_CULQU
Length = 1097
Score = 77.8 bits (190), Expect = 4e-13
Identities = 53/150 (35%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQ-- 261
+DS+ ++ ASL PE + IA+P++SWLDD++ W+S + GCCR T+GS+C +
Sbjct: 547 TDSVQTQLYLASLYPEITRIARPSSSWLDDYIDWLSID--GCCRYNATDGSFCMSTNTAC 604
Query: 260 PPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
PPC DD+ V R + QF L +FLS LP CAK G
Sbjct: 605 PPCPKEFDDTGV-------------------RPTVAQFERYLEFFLSDLPDDRCAKAGRA 645
Query: 80 AYTSSV----DLKG----YDSALFKHHRSV 15
AY S++ D +G +DS +H +V
Sbjct: 646 AYLSAMNYVADSQGHVNVHDSYFMSYHTTV 675
Score = 70.1 bits (170), Expect = 7e-11
Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 12/150 (8%)
Frame = -2
Query: 428 DSLLN-EISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQ-- 261
D+LL+ +S A++ T+ IA+P++SWLDD++ W+S + GCCR T+GS+C +
Sbjct: 727 DTLLSLGLSLAAVFVVTTRIARPSSSWLDDYIDWLSID--GCCRYNATDGSFCMSTNTAC 784
Query: 260 PPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
PPC DD+ V R + QF L +FLS LP CAK G
Sbjct: 785 PPCPKEFDDTGV-------------------RPTVAQFERYLEFFLSDLPDDRCAKAGRA 825
Query: 80 AYTSSV----DLKG----YDSALFKHHRSV 15
AY S++ D +G +DS +H +V
Sbjct: 826 AYLSAMNYVADSQGHVNVHDSYFMSYHTTV 855
[54][TOP]
>UniRef100_A8MSP5 NPC1 (Niemann-Pick disease, type C1, gene)-like 1, isoform CRA_a n=1
Tax=Homo sapiens RepID=A8MSP5_HUMAN
Length = 1359
Score = 77.0 bits (188), Expect = 6e-13
Identities = 45/127 (35%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
S +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + +G +CP
Sbjct: 929 SFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYISGPNKDKFCPSTVNS 986
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C S G+ R S QF LPWFL+ P+ C KGG A
Sbjct: 987 LNCLKNCMSITMGSV---------------RPSVEQFHKYLPWFLNDRPNIKCPKGGLAA 1031
Query: 77 YTSSVDL 57
Y++SV+L
Sbjct: 1032 YSTSVNL 1038
[55][TOP]
>UniRef100_Q9UHC9 Niemann-Pick C1-like protein 1 n=1 Tax=Homo sapiens RepID=NPCL1_HUMAN
Length = 1359
Score = 77.0 bits (188), Expect = 6e-13
Identities = 45/127 (35%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
S +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + +G +CP
Sbjct: 929 SFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYISGPNKDKFCPSTVNS 986
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C S G+ R S QF LPWFL+ P+ C KGG A
Sbjct: 987 LNCLKNCMSITMGSV---------------RPSVEQFHKYLPWFLNDRPNIKCPKGGLAA 1031
Query: 77 YTSSVDL 57
Y++SV+L
Sbjct: 1032 YSTSVNL 1038
[56][TOP]
>UniRef100_UPI000069E05A Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05A
Length = 1319
Score = 76.6 bits (187), Expect = 8e-13
Identities = 45/122 (36%), Positives = 62/122 (50%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL +I A+ P+ SY+A PA+SW+DDF+ W++P + CCR NG++C
Sbjct: 937 DSLTQKIQYATEYPDRSYLAIPASSWVDDFIDWLNPTS-DCCRLLLNGTFC--------- 986
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
S + A C S R + QF LP FL+ P+ C KGG GAY +
Sbjct: 987 -----SSTNTALPGCLRKCMPSTTGALRPNLEQFNTYLPVFLNDYPNLKCPKGGLGAYDN 1041
Query: 68 SV 63
SV
Sbjct: 1042 SV 1043
[57][TOP]
>UniRef100_Q6T3U3 Niemann-Pick C1-like protein 1 n=1 Tax=Rattus norvegicus
RepID=NPCL1_RAT
Length = 1331
Score = 76.3 bits (186), Expect = 1e-12
Identities = 48/144 (33%), Positives = 68/144 (47%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDD 264
S SL +I AS P+ SY+A A+SW+DDF+ W++P + CCR + G +CP D
Sbjct: 927 SFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSS-SCCRLYIRGPHKDEFCPSTD 985
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C K+C + L R + QF LPWFL+ P+ C KGG
Sbjct: 986 TSFNC-----------LKNC----MNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGL 1030
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY +SV+L + + H
Sbjct: 1031 AAYRTSVNLSSDGQVIASQFMAYH 1054
[58][TOP]
>UniRef100_UPI00019513D7 UPI00019513D7 related cluster n=1 Tax=Bos taurus RepID=UPI00019513D7
Length = 1324
Score = 75.9 bits (185), Expect = 1e-12
Identities = 47/136 (34%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
SL +I A+ P+ SY+A PA+SW+DDF+ W++ + CCR + +G +CP
Sbjct: 931 SLTQKIQYATDFPDMSYLAIPASSWVDDFIDWLTSSS--CCRLYISGPNKDEFCPSTVNS 988
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C +CVS R S QF LPWFLS P+ C KGG A
Sbjct: 989 LACLK---TCVSPTAGSA------------RPSVEQFHKYLPWFLSDEPNIKCPKGGLAA 1033
Query: 77 YTSSVDLKGYDSALFK 30
Y++SV++ L K
Sbjct: 1034 YSTSVNMSSDGQILGK 1049
[59][TOP]
>UniRef100_UPI00005BC4A6 PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Bos taurus RepID=UPI00005BC4A6
Length = 1333
Score = 75.5 bits (184), Expect = 2e-12
Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 4/127 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNG----SYCPPDDQP 258
SL +I A+ P+ SY+A PA+SW+DDF+ W++ + CCR + +G +CP
Sbjct: 931 SLTQKIQYATDFPDMSYLAIPASSWVDDFIDWLTSSS--CCRLYISGPNKDEFCPSTVNS 988
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
C +CVS R S QF LPWFLS P+ C KGG A
Sbjct: 989 LACLK---TCVSPTAGSA------------RPSVEQFHKYLPWFLSDEPNIKCPKGGLAA 1033
Query: 77 YTSSVDL 57
Y++SV++
Sbjct: 1034 YSTSVNM 1040
[60][TOP]
>UniRef100_A0MJA7 Niemann-Pick C1-like 1 protein n=1 Tax=Oryctolagus cuniculus
RepID=A0MJA7_RABIT
Length = 1325
Score = 75.5 bits (184), Expect = 2e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
S SL +I A+ PE SY+A PA+SW+DDF+ W++P + CCR + G
Sbjct: 926 SFSLTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSS--CCRLYILG----------- 972
Query: 251 CAPEDDSCVSGACKDCTTCFRHS---DLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHG 81
+D+ C S + C R+ L R S QF LPWFL+ P+ C KGG
Sbjct: 973 -PNKDEFCPSTV--NSLNCLRNCMSLTLGPVRPSVEQFHKYLPWFLNDPPNIRCPKGGLA 1029
Query: 80 AYTSSVDL 57
AY++SV+L
Sbjct: 1030 AYSTSVNL 1037
[61][TOP]
>UniRef100_B3S409 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S409_TRIAD
Length = 1218
Score = 75.5 bits (184), Expect = 2e-12
Identities = 47/148 (31%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEA-FGCCRKFTNGS----YCPPD 267
+DSL+ +I AS +YIA+ +SW+DD+ WI P CCRK G +CP
Sbjct: 868 ADSLVQQIYVASEQANYTYIAETTSSWIDDYFAWIQPVGKIPCCRKRPVGKGHYKFCPST 927
Query: 266 DQPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGG 87
+ C P C +D+ R + +F LPWFL +P CAKGG
Sbjct: 928 EVNQSCVP---------------CLPSTDIGR-RPTGKEFIKYLPWFLEDVPGKICAKGG 971
Query: 86 HGAYTSSV----DLKGYDSALFKHHRSV 15
H AY S++ D K + F + ++
Sbjct: 972 HAAYGSAIKFTRDKKNISATYFMTYHNI 999
[62][TOP]
>UniRef100_UPI0000F2B5DF PREDICTED: similar to Niemann-Pick C1-like 1 protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2B5DF
Length = 1331
Score = 75.1 bits (183), Expect = 2e-12
Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
SL +I A+ P+ SY+A PA+SW+DDF+ W++P + CCR + N ++C
Sbjct: 926 SLTQKIQYATEFPKESYLAIPASSWVDDFIDWLTPTS-DCCRLYRNNTFC---------- 974
Query: 245 PEDDSCVSGACKDCTTCFRHS---DLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
S G TCFR R + QF LPWFL + C KGG GAY
Sbjct: 975 ----SSTEGT---VLTCFRKCIPYTTSTVRPTVEQFHKYLPWFLEDKANIKCPKGGLGAY 1027
Query: 74 TSSVDLKGYDSALFKHHRSVH 12
+V++ L + H
Sbjct: 1028 DGAVNISADGEILATRFMAYH 1048
[63][TOP]
>UniRef100_UPI0001792008 PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA n=1
Tax=Acyrthosiphon pisum RepID=UPI0001792008
Length = 1117
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
S+ N+I +AS + +YI +P+ SW+DD+ W S + CC+ N S+CP +
Sbjct: 777 SIANQIYRASKMANVTYINRPSTSWIDDYFDWSSLSS--CCKVTQNNSFCPHSSE----- 829
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
DCT+C + ++ND R F LP+FL P C+K GH AY+
Sbjct: 830 ------------DCTSC---NIIKNDWGRPDVQHFAKFLPYFLQDSPDQKCSKAGHAAYS 874
Query: 71 SSVDLK 54
++ K
Sbjct: 875 DAISFK 880
[64][TOP]
>UniRef100_UPI000175F27F PREDICTED: im:7149020, partial n=1 Tax=Danio rerio
RepID=UPI000175F27F
Length = 598
Score = 74.7 bits (182), Expect = 3e-12
Identities = 45/127 (35%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I ASL+ + I+ +SWLDD+ W+ P++ CCR + + G++C
Sbjct: 238 NDSLVQQIYTASLMSNYTRISNVPSSWLDDYFDWVKPQST-CCRYYNSTGAFC------- 289
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V +C C R + T M F LP FLS P+ C KGGH AY
Sbjct: 290 -----NASVVDKSCVHCRPMTSSGKQRPNGTEFMHF---LPMFLSDNPNIKCGKGGHAAY 341
Query: 74 TSSVDLK 54
++VDLK
Sbjct: 342 GTAVDLK 348
[65][TOP]
>UniRef100_UPI0001758A11 PREDICTED: similar to niemann-pick C1 n=1 Tax=Tribolium castaneum
RepID=UPI0001758A11
Length = 1306
Score = 74.7 bits (182), Expect = 3e-12
Identities = 40/123 (32%), Positives = 59/123 (47%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL+ ++ +AS VPE +YIA+P++SWLDD++ W + C T G++CP
Sbjct: 941 DSLITQVFEASKVPERTYIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFCPH------- 993
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
G C C + N R + F + +FL P CAK GH AY+
Sbjct: 994 -------TKGTCATCNISYLP---LNHRPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQ 1043
Query: 68 SVD 60
V+
Sbjct: 1044 GVN 1046
[66][TOP]
>UniRef100_UPI0001A2D25E hypothetical protein LOC553611 n=1 Tax=Danio rerio
RepID=UPI0001A2D25E
Length = 1076
Score = 74.7 bits (182), Expect = 3e-12
Identities = 45/127 (35%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I ASL+ + I+ +SWLDD+ W+ P++ CCR + + G++C
Sbjct: 898 NDSLVQQIYTASLMSNYTRISNVPSSWLDDYFDWVKPQST-CCRYYNSTGAFC------- 949
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V +C C R + T M F LP FLS P+ C KGGH AY
Sbjct: 950 -----NASVVDKSCVHCRPMTSSGKQRPNGTEFMHF---LPMFLSDNPNIKCGKGGHAAY 1001
Query: 74 TSSVDLK 54
++VDLK
Sbjct: 1002 GTAVDLK 1008
[67][TOP]
>UniRef100_Q7PS03 AGAP000579-PA (Fragment) n=1 Tax=Anopheles gambiae RepID=Q7PS03_ANOGA
Length = 1247
Score = 74.7 bits (182), Expect = 3e-12
Identities = 43/124 (34%), Positives = 67/124 (54%), Gaps = 1/124 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+ ++ +ASL PET++IA+PA+SWLDD++ W++ ++ CC+ T+GS+C
Sbjct: 891 DSISTKLYQASLYPETTHIARPASSWLDDYIDWLAIQS--CCKYNPTDGSFC-------- 940
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
S C C D R + QF L +FLS LP +CAK G AY+
Sbjct: 941 -------ASSKYIVFCPACPEEYDETGIRPTVPQFERYLEFFLSDLPDENCAKAGRAAYS 993
Query: 71 SSVD 60
+++
Sbjct: 994 RALN 997
[68][TOP]
>UniRef100_UPI000186F3A4 Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186F3A4
Length = 1233
Score = 74.3 bits (181), Expect = 4e-12
Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
SDS + +SKAS SY+AK +SW+DD+ W+S + CC++F N S+CP +
Sbjct: 897 SDSFVTYLSKASKHSNVSYLAKSPSSWIDDYFDWLS-NSNSCCKEFKVNSSFCPHQRE-- 953
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ C +C H L + R + F+ LP+FL+ P +C KGGH Y
Sbjct: 954 --------------EGCQSCQIH--LVDWRPTKNDFKKYLPYFLNDNPDVNCVKGGHPLY 997
Query: 74 TSSVDLKGYDS 42
++ V+ + YD+
Sbjct: 998 STGVNFE-YDT 1007
[69][TOP]
>UniRef100_A0MJA8 Niemann-Pick C1-like 1 protein n=1 Tax=Mesocricetus auratus
RepID=A0MJA8_MESAU
Length = 1328
Score = 74.3 bits (181), Expect = 4e-12
Identities = 47/144 (32%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF----TNGSYCPPDD 264
S S+ +I A+ PE SYI A+SW+DDF+ W++P + CCR + G +CP D
Sbjct: 928 SFSMTQKIQYATEFPEQSYIGIAASSWVDDFIDWLTPSS--CCRLYIFGPNTGDFCPSTD 985
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C K+C + L R + QF LPWFL P+ C KGG
Sbjct: 986 TSLSC-----------LKNC----MNFTLGPVRPTAEQFHKYLPWFLDDPPNIRCPKGGL 1030
Query: 83 GAYTSSVDLKGYDSALFKHHRSVH 12
AY +SV+L + + H
Sbjct: 1031 AAYRTSVNLSSDGQIIASQFMAYH 1054
[70][TOP]
>UniRef100_C3ZSN0 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3ZSN0_BRAFL
Length = 1368
Score = 74.3 bits (181), Expect = 4e-12
Identities = 47/130 (36%), Positives = 67/130 (51%), Gaps = 2/130 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG-CCRKFTNGS-YCPPDDQPP 255
DSL+ +I A L+ + S I +SW+DD+ W++P CCR + N +C
Sbjct: 985 DSLVQQIGDAHLIADYSKIFAAPSSWMDDYFDWMNPLGNPPCCRVYNNTERFCN------ 1038
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ + D+CV C D R R +F + LP FL+ +P+ DCAKGGH AY
Sbjct: 1039 -ASVDSDTCVG--------CRSPKD-RGIRPVHDEFMEFLPMFLTDVPTTDCAKGGHAAY 1088
Query: 74 TSSVDLKGYD 45
S+VDLK D
Sbjct: 1089 NSAVDLKRND 1098
[71][TOP]
>UniRef100_A8IYI0 Sterol sensing domain protein (Fragment) n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IYI0_CHLRE
Length = 717
Score = 73.6 bits (179), Expect = 7e-12
Identities = 37/75 (49%), Positives = 43/75 (57%)
Frame = -2
Query: 287 GSYCPPDDQPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPS 108
GSYCPP DQPPC S + C C TC + R S QF+ LPWFL A PS
Sbjct: 524 GSYCPPPDQPPC------STNASTCAGCRTCVQ------GRPSVSQFQSYLPWFLGARPS 571
Query: 107 ADCAKGGHGAYTSSV 63
CAKGG GAY+S++
Sbjct: 572 EGCAKGGVGAYSSAL 586
[72][TOP]
>UniRef100_UPI00017B0961 UPI00017B0961 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B0961
Length = 1266
Score = 73.2 bits (178), Expect = 9e-12
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ ++ ASL+ S IA +SWLDD+ W+ P + CCR + G++C
Sbjct: 910 NDSLVQQVYYASLISNYSTIANTPSSWLDDYFDWVKPRS-SCCRYYNGTGAFC------- 961
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V+ +C C R M+F LP FLS P+ C KGGH AY
Sbjct: 962 -----NASVVNSSCVHCRPMTPSGMQRPVGDDFMRF---LPMFLSDNPNVKCGKGGHAAY 1013
Query: 74 TSSVDL 57
+++VDL
Sbjct: 1014 STAVDL 1019
[73][TOP]
>UniRef100_Q4RWY5 Chromosome 15 SCAF14981, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RWY5_TETNG
Length = 1209
Score = 73.2 bits (178), Expect = 9e-12
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ ++ ASL+ S IA +SWLDD+ W+ P + CCR + G++C
Sbjct: 879 NDSLVQQVYYASLISNYSTIANTPSSWLDDYFDWVKPRS-SCCRYYNGTGAFC------- 930
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V+ +C C R M+F LP FLS P+ C KGGH AY
Sbjct: 931 -----NASVVNSSCVHCRPMTPSGMQRPVGDDFMRF---LPMFLSDNPNVKCGKGGHAAY 982
Query: 74 TSSVDL 57
+++VDL
Sbjct: 983 STAVDL 988
[74][TOP]
>UniRef100_B4JXM3 GH17745 n=1 Tax=Drosophila grimshawi RepID=B4JXM3_DROGR
Length = 1246
Score = 73.2 bits (178), Expect = 9e-12
Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF--TNGSYCPPDDQPP 255
DSL ++ S P+ + +A+PA+SW+DD++ WIS G C K+ T GS+CP + +
Sbjct: 889 DSLSVQLYTQSRYPDITGLARPASSWIDDYIDWIS---IGDCCKYNITTGSFCPSNSKSD 945
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
DC C R R S+ F +P+FLS LP A+CAK G +Y
Sbjct: 946 ---------------DCLPCEREFSENGLRPSSDTFDKYVPFFLSDLPDAECAKAGRASY 990
Query: 74 TSSV 63
++
Sbjct: 991 ADAI 994
[75][TOP]
>UniRef100_B3MPM8 GF14130 n=1 Tax=Drosophila ananassae RepID=B3MPM8_DROAN
Length = 1286
Score = 72.8 bits (177), Expect = 1e-11
Identities = 48/125 (38%), Positives = 63/125 (50%), Gaps = 3/125 (2%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+L +I AS +YIA+PA+SWLDD+ W S ++ CC+ +NGS+CP D
Sbjct: 917 DSVLTQIYLASRHSNQTYIARPASSWLDDYFDWSSTQS--CCKFNPSNGSFCPHQD---- 970
Query: 251 CAPEDDSCVSGACKDCTTC--FRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
CT C ++S R D S F LP+FL P CAK GH A
Sbjct: 971 -------------TSCTNCNISKNSIQRPDEKS---FDKYLPFFLKDNPDDSCAKAGHAA 1014
Query: 77 YTSSV 63
Y S+V
Sbjct: 1015 YGSAV 1019
[76][TOP]
>UniRef100_UPI00015B5F3E PREDICTED: similar to CG5722-PA n=1 Tax=Nasonia vitripennis
RepID=UPI00015B5F3E
Length = 1253
Score = 72.4 bits (176), Expect = 1e-11
Identities = 40/124 (32%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPPC 252
DSL +I A+ +YIA+PA+SW+DD+ W + ++ CC+ F+ NG++CP D
Sbjct: 908 DSLYLQIFSAANRSSETYIAQPASSWIDDYYDWTTIDS--CCKYFSENGTFCPHD----- 960
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
G+C+ C + + R ST FR +P+FL+ +P CAK G Y
Sbjct: 961 ---------KGSCEKC--AIARDETYDLRPSTKDFRKYIPFFLTDVPDPTCAKAGRSTYL 1009
Query: 71 SSVD 60
++
Sbjct: 1010 DGIN 1013
[77][TOP]
>UniRef100_UPI000186EA3E Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186EA3E
Length = 1278
Score = 71.6 bits (174), Expect = 3e-11
Identities = 45/125 (36%), Positives = 60/125 (48%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL ++ AS +SYIA PA+SWLDD+ W+S + CC N S+CP
Sbjct: 892 DSLTTQVYLASKQANSSYIATPASSWLDDYFDWLSYDK--CCFVTNNKSFCPHISP---- 945
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
DC TC R + R S+ F L +FL P A CAKGGH +Y
Sbjct: 946 ------------YDCETCPR-ENATGIRPSSTDFERYLSFFLKDDPDASCAKGGHPSYGP 992
Query: 68 SVDLK 54
+V+ +
Sbjct: 993 AVNYR 997
[78][TOP]
>UniRef100_UPI000180CC29 PREDICTED: Niemann-Pick disease, type C1 n=1 Tax=Ciona intestinalis
RepID=UPI000180CC29
Length = 1366
Score = 71.6 bits (174), Expect = 3e-11
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG----CCR--KFTNGSYCPPDD 264
SL +IS AS I PAASW DD++ W+ P+ G CCR F +CP D
Sbjct: 957 SLTQQISYASQNASYWRIETPAASWYDDYVDWLPPQGVGGRKSCCRYETFHPNEFCPATD 1016
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C+P C ++ D D F LPWFL P +C KGGH
Sbjct: 1017 TVSKCSP---------------CLKNEDYTPD-----DFMQYLPWFLIDNPGVECNKGGH 1056
Query: 83 GAYTSSVDL 57
AY ++V++
Sbjct: 1057 SAYGNAVNI 1065
[79][TOP]
>UniRef100_UPI0000E7FEDB PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Gallus gallus
RepID=UPI0000E7FEDB
Length = 1261
Score = 71.6 bits (174), Expect = 3e-11
Identities = 41/126 (32%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
+DSL+ ++ A+ + + I +SW+DD+ W+ P++ CCR + T G +C P
Sbjct: 900 NDSLVQQVFNAAEISSYTRIGYAPSSWIDDYFDWVKPQS-SCCRVYNTTGQFCNASVTDP 958
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
CT C S R F LP FLS P+ C KGGH AY
Sbjct: 959 ---------------SCTRCRPLSQEGKQRPQGEDFMTFLPMFLSDNPNPKCGKGGHAAY 1003
Query: 74 TSSVDL 57
+S+VDL
Sbjct: 1004 SSAVDL 1009
[80][TOP]
>UniRef100_UPI000060FC24 Niemann-Pick C1 protein precursor. n=1 Tax=Gallus gallus
RepID=UPI000060FC24
Length = 1278
Score = 71.6 bits (174), Expect = 3e-11
Identities = 41/126 (32%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
+DSL+ ++ A+ + + I +SW+DD+ W+ P++ CCR + T G +C P
Sbjct: 917 NDSLVQQVFNAAEISSYTRIGYAPSSWIDDYFDWVKPQS-SCCRVYNTTGQFCNASVTDP 975
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
CT C S R F LP FLS P+ C KGGH AY
Sbjct: 976 ---------------SCTRCRPLSQEGKQRPQGEDFMTFLPMFLSDNPNPKCGKGGHAAY 1020
Query: 74 TSSVDL 57
+S+VDL
Sbjct: 1021 SSAVDL 1026
[81][TOP]
>UniRef100_Q4H344 Niemann-Pick disease, type C1 (Fragment) n=1 Tax=Ciona intestinalis
RepID=Q4H344_CIOIN
Length = 620
Score = 71.6 bits (174), Expect = 3e-11
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFG----CCR--KFTNGSYCPPDD 264
SL +IS AS I PAASW DD++ W+ P+ G CCR F +CP D
Sbjct: 211 SLTQQISYASQNASYWRIETPAASWYDDYVDWLPPQGVGGRKSCCRYETFHPNEFCPATD 270
Query: 263 QPPCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGH 84
C+P C ++ D D F LPWFL P +C KGGH
Sbjct: 271 TVSKCSP---------------CLKNEDYTPD-----DFMQYLPWFLIDNPGVECNKGGH 310
Query: 83 GAYTSSVDL 57
AY ++V++
Sbjct: 311 SAYGNAVNI 319
[82][TOP]
>UniRef100_Q16VL3 Niemann-pick C1 n=1 Tax=Aedes aegypti RepID=Q16VL3_AEDAE
Length = 1266
Score = 71.6 bits (174), Expect = 3e-11
Identities = 45/151 (29%), Positives = 75/151 (49%), Gaps = 9/151 (5%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
+DS+ ++ AS PE + IA+P++SWLDD++ W++ + GCCR T+GS+C +
Sbjct: 903 ADSVQTQLYLASRYPEITRIARPSSSWLDDYIDWLAID--GCCRYNRTDGSFCLSSN--- 957
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C +C R D R + QF + +FLS +P CAK G AY
Sbjct: 958 --------------TFCESCPREFDETGVRPTVEQFERYMEFFLSDIPDDRCAKAGRAAY 1003
Query: 74 TSSVD--------LKGYDSALFKHHRSVHIT 6
++++ L +DS +H +V ++
Sbjct: 1004 LTALNYVTDSAGHLNVHDSYFMSYHTTVVVS 1034
[83][TOP]
>UniRef100_UPI00017610E4 PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Danio rerio RepID=UPI00017610E4
Length = 1087
Score = 70.9 bits (172), Expect = 4e-11
Identities = 46/121 (38%), Positives = 63/121 (52%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
S+ +I A+ PE SY+A PA+SW+DD++ W++P + CCR +T G P+ C A
Sbjct: 799 SMTQKIRYATEYPERSYLAIPASSWVDDYIDWLNPGS-RCCRLYTFG----PNKDEFCPA 853
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSS 66
E C+ K C + LR D +F LP FLS P C KGG GAY +
Sbjct: 854 NETGVCL----KKCMGKPENGVLRPD---VSEFNRFLPDFLSNRPDLQCPKGGLGAYDKA 906
Query: 65 V 63
V
Sbjct: 907 V 907
[84][TOP]
>UniRef100_UPI0001A2D2B7 Novel protein similar to human and mouse intersectin 2 (ITSN2) n=1
Tax=Danio rerio RepID=UPI0001A2D2B7
Length = 1260
Score = 70.9 bits (172), Expect = 4e-11
Identities = 46/121 (38%), Positives = 63/121 (52%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
S+ +I A+ PE SY+A PA+SW+DD++ W++P + CCR +T G P+ C A
Sbjct: 905 SMTQKIRYATEYPERSYLAIPASSWVDDYIDWLNPGS-RCCRLYTFG----PNKDEFCPA 959
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSS 66
E C+ K C + LR D +F LP FLS P C KGG GAY +
Sbjct: 960 NETGVCL----KKCMGKPENGVLRPD---VSEFNRFLPDFLSNRPDLQCPKGGLGAYDKA 1012
Query: 65 V 63
V
Sbjct: 1013 V 1013
[85][TOP]
>UniRef100_Q9GK52 Niemann-Pick type C1 disease protein n=1 Tax=Canis lupus familiaris
RepID=Q9GK52_CANFA
Length = 1276
Score = 70.1 bits (170), Expect = 7e-11
Identities = 42/133 (31%), Positives = 67/133 (50%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I A+ + ++I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 915 NDSLVQQIFSAAQLDNYTHIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDQFC------- 966
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C + R M+F LP FLS P+ C KGGH AY
Sbjct: 967 -----NASVVDPACVRCRPLTQEGKRRPQGEDFMRF---LPMFLSDNPNPKCGKGGHAAY 1018
Query: 74 TSSVDLKGYDSAL 36
S+V+L G D+++
Sbjct: 1019 GSAVNLVGNDTSV 1031
[86][TOP]
>UniRef100_B4KJH6 GI18274 (Fragment) n=1 Tax=Drosophila mojavensis RepID=B4KJH6_DROMO
Length = 1253
Score = 70.1 bits (170), Expect = 7e-11
Identities = 47/146 (32%), Positives = 69/146 (47%), Gaps = 8/146 (5%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+L +I AS +YIA+PA+SW+DD+ W + CC+ TNGS+CP D
Sbjct: 886 DSVLTQIYLASRKSNLTYIARPASSWIDDYFDWALSSS--CCKYNPTNGSFCPHQD---- 939
Query: 251 CAPEDDSCVSGACKDCTTC-FRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C+TC + ++L+ R + +F LP+FL P C K GH AY
Sbjct: 940 -------------TSCSTCEIQKNNLQ--RPNEHEFGKYLPFFLKDNPDDSCVKAGHAAY 984
Query: 74 TSSVDLK------GYDSALFKHHRSV 15
+V DS+ F + S+
Sbjct: 985 NGAVRYSFEENKINIDSSYFMAYHSI 1010
[87][TOP]
>UniRef100_UPI0000586B35 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000586B35
Length = 1332
Score = 69.3 bits (168), Expect = 1e-10
Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 2/125 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEA-FGCCR-KFTNGSYCPPDDQPP 255
+SL ++I A+ + + + +A P++SW+DDF W+ P + CCR G +CP D
Sbjct: 956 NSLTSQIYFAAELSQYTRVAHPSSSWMDDFFDWVKPNSNLTCCRVNNETGDFCPSTDT-- 1013
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
KD T R ++ R + +F + LP+FL +P C+KGG AY
Sbjct: 1014 --------------KDTCTSCRPLSEQDKRPTPEEFEEFLPFFLEDIPGISCSKGGKAAY 1059
Query: 74 TSSVD 60
S+V+
Sbjct: 1060 ASAVN 1064
[88][TOP]
>UniRef100_UPI00016E624E UPI00016E624E related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E624E
Length = 1264
Score = 68.6 bits (166), Expect = 2e-10
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
++SL+ ++ ASL+ + +A +SWLDD+ W+ P++ CCR + G++C
Sbjct: 908 NNSLVQQVYTASLISNYTTVAYTPSSWLDDYFDWVKPQS-TCCRYYNGTGAFC------- 959
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V+ +C C R M+F LP FLS P+ C KGGH AY
Sbjct: 960 -----NASVVNSSCVHCRPMTPSGKERPVGDDFMRF---LPMFLSDNPNVKCGKGGHAAY 1011
Query: 74 TSSVDL 57
++VDL
Sbjct: 1012 GTAVDL 1017
[89][TOP]
>UniRef100_UPI0000EB3851 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3851
Length = 1285
Score = 68.6 bits (166), Expect = 2e-10
Identities = 42/133 (31%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 924 NDSLVQQIFSAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDQFC------- 975
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C + R M+F LP FLS P+ C KGGH AY
Sbjct: 976 -----NASVVDPACVRCRPLTQEGKRRPQGEDFMRF---LPMFLSDNPNPKCGKGGHAAY 1027
Query: 74 TSSVDLKGYDSAL 36
S+V+L G D+++
Sbjct: 1028 GSAVNLVGNDTSV 1040
[90][TOP]
>UniRef100_UPI0000EB3850 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3850
Length = 1277
Score = 68.6 bits (166), Expect = 2e-10
Identities = 42/133 (31%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 916 NDSLVQQIFSAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C + R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTQEGKRRPQGEDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDSAL 36
S+V+L G D+++
Sbjct: 1020 GSAVNLVGNDTSV 1032
[91][TOP]
>UniRef100_B4PYK8 GE17898 n=1 Tax=Drosophila yakuba RepID=B4PYK8_DROYA
Length = 1252
Score = 68.2 bits (165), Expect = 3e-10
Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S PE + +A+PA+SWLDD++ W++ CC+ T G +C + +
Sbjct: 895 NNSLSVQLYTQSRYPEITALARPASSWLDDYIDWLAIS--DCCKYNITTGGFCSSNSKSE 952
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F + LR D + F +P+FL LP A+CAK G +Y
Sbjct: 953 DCLP------------CERGFTENGLRPDAET---FNKYIPYFLFDLPDAECAKAGRASY 997
Query: 74 TSSV 63
+V
Sbjct: 998 ADAV 1001
[92][TOP]
>UniRef100_Q6CBA1 YALI0C20757p n=1 Tax=Yarrowia lipolytica RepID=Q6CBA1_YARLI
Length = 1239
Score = 68.2 bits (165), Expect = 3e-10
Identities = 45/145 (31%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR--KFTNGSYCPPDDQPPC 252
SL+N + + PE SYI++PA+SW+DD+L W++P+ CCR K CPP P
Sbjct: 864 SLVNIVEQERKRPELSYISEPASSWIDDYLKWLNPDLDECCRVKKTDKDVACPPRASP-- 921
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTST-----MQFRDKLPWFLSALPSADCAKGG 87
+ C CF+ D + T + +F +++ A PS C GG
Sbjct: 922 -------------RACNVCFKDRDPAWNITMSGLPQGPEFMHYFDFWIDA-PSDPCPLGG 967
Query: 86 HGAYTSSVDLKGYDSALFKHHRSVH 12
Y+ +V + D L H RS H
Sbjct: 968 KAPYSDAV-VYDSDDVLTSHFRSFH 991
[93][TOP]
>UniRef100_B4NZ62 GE26328 n=1 Tax=Drosophila yakuba RepID=B4NZ62_DROYA
Length = 1287
Score = 67.8 bits (164), Expect = 4e-10
Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS+L +I AS +YIA+PA+SW+DD+ W + A C + G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAAASCCKYRKDTGDFCPHQD----- 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
T+C + + +N R +F LP+FL P CAK GH AY
Sbjct: 973 ---------------TSCLKCNITKNALLRPEAKEFEKYLPFFLKDNPDDTCAKAGHAAY 1017
Query: 74 TSSV 63
+V
Sbjct: 1018 GGAV 1021
[94][TOP]
>UniRef100_B4HWH4 GM11941 n=1 Tax=Drosophila sechellia RepID=B4HWH4_DROSE
Length = 1287
Score = 67.8 bits (164), Expect = 4e-10
Identities = 43/125 (34%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+L +I AS +YIA+PA+SW+DD+ W + A CCR + G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDW-AAAASSCCRYRKDTGDFCPHQD---- 972
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
T+C R + +N R +F LP+FL P CAK GH A
Sbjct: 973 ----------------TSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAA 1016
Query: 77 YTSSV 63
Y +V
Sbjct: 1017 YGGAV 1021
[95][TOP]
>UniRef100_Q9N0Q0 Niemann-Pick type C1 disease protein n=1 Tax=Felis catus
RepID=Q9N0Q0_FELCA
Length = 1276
Score = 67.4 bits (163), Expect = 5e-10
Identities = 41/133 (30%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGS-YCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 915 NDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDRFC------- 966
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C + R M+F LP FLS P+ C KGGH AY
Sbjct: 967 -----NASVVDPACIRCRPLTQEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1018
Query: 74 TSSVDLKGYDSAL 36
+S+V++ G D+ +
Sbjct: 1019 SSAVNILGNDTGV 1031
[96][TOP]
>UniRef100_Q8MKD8 Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MKD8_FELCA
Length = 1276
Score = 67.4 bits (163), Expect = 5e-10
Identities = 41/133 (30%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGS-YCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 915 NDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDRFC------- 966
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C + R M+F LP FLS P+ C KGGH AY
Sbjct: 967 -----NASVVDPACIRCRPLTQEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1018
Query: 74 TSSVDLKGYDSAL 36
+S+V++ G D+ +
Sbjct: 1019 SSAVNILGNDTGV 1031
[97][TOP]
>UniRef100_Q9VL24 Niemann-Pick type C-1 n=1 Tax=Drosophila melanogaster
RepID=Q9VL24_DROME
Length = 1287
Score = 67.4 bits (163), Expect = 5e-10
Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS+L +I AS +YIA+PA+SW+DD+ W + + C + +G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQD----- 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
T+C R + +N R +F LP+FL P CAK GH AY
Sbjct: 973 ---------------TSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAY 1017
Query: 74 TSSV 63
+V
Sbjct: 1018 GGAV 1021
[98][TOP]
>UniRef100_Q9U5W1 NPC1 protein n=1 Tax=Drosophila melanogaster RepID=Q9U5W1_DROME
Length = 1287
Score = 67.4 bits (163), Expect = 5e-10
Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS+L +I AS +YIA+PA+SW+DD+ W + + C + +G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQD----- 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
T+C R + +N R +F LP+FL P CAK GH AY
Sbjct: 973 ---------------TSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAY 1017
Query: 74 TSSV 63
+V
Sbjct: 1018 GGAV 1021
[99][TOP]
>UniRef100_Q7YU59 RE56428p n=1 Tax=Drosophila melanogaster RepID=Q7YU59_DROME
Length = 1287
Score = 67.4 bits (163), Expect = 5e-10
Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS+L +I AS +YIA+PA+SW+DD+ W + + C + +G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCPHQD----- 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
T+C R + +N R +F LP+FL P CAK GH AY
Sbjct: 973 ---------------TSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAY 1017
Query: 74 TSSV 63
+V
Sbjct: 1018 GGAV 1021
[100][TOP]
>UniRef100_B4L379 GI15499 n=1 Tax=Drosophila mojavensis RepID=B4L379_DROMO
Length = 1217
Score = 67.4 bits (163), Expect = 5e-10
Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWIS-PEAFGCCR-KFTNGSYCPPDDQPP 255
DSL ++ S P+ + +A+PA+SW+DD++ W++ P+ CC+ T GS+CP + +
Sbjct: 872 DSLSVQLYIQSRYPQITSLARPASSWIDDYIDWLNIPD---CCKINATTGSFCPSNSKSD 928
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
DC C R R ++ F +P FLS LP A+CAK G +Y
Sbjct: 929 ---------------DCYPCEREFTENGLRPTSETFDKYVPLFLSDLPDAECAKAGRPSY 973
Query: 74 TSSV 63
+V
Sbjct: 974 ADAV 977
[101][TOP]
>UniRef100_B4JPL7 GH13378 n=1 Tax=Drosophila grimshawi RepID=B4JPL7_DROGR
Length = 1021
Score = 67.4 bits (163), Expect = 5e-10
Identities = 44/123 (35%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+L +I AS SYIA+PA+SW+DD+ W + + CC+ NGS+CP D
Sbjct: 914 DSVLTQIYMASRRSNISYIARPASSWVDDYFDWAA--SSDCCKYNPKNGSFCPHQDY--- 968
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+C +C +DL+ R +F LP FL P CAK GH AY+
Sbjct: 969 -----------SCSNCK--IPKNDLK--RPDEHEFGKYLPGFLHDNPDELCAKAGHAAYS 1013
Query: 71 SSV 63
+V
Sbjct: 1014 GAV 1016
[102][TOP]
>UniRef100_B4Q8Q7 GD22294 n=1 Tax=Drosophila simulans RepID=B4Q8Q7_DROSI
Length = 1251
Score = 67.0 bits (162), Expect = 6e-10
Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DS+L +I AS +YIA+PA+SW+DD+ W + + C + G +CP D
Sbjct: 918 DSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDTGDFCPHQD----- 972
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
T+C R + +N R +F LP+FL P CAK GH AY
Sbjct: 973 ---------------TSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPDDTCAKAGHAAY 1017
Query: 74 TSSV 63
+V
Sbjct: 1018 GGAV 1021
[103][TOP]
>UniRef100_UPI000194BC77 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Taeniopygia guttata
RepID=UPI000194BC77
Length = 1280
Score = 66.6 bits (161), Expect = 8e-10
Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
+DSL+ ++ A+ + + I +SW+DD+ W+ P++ CCR + T G +C P
Sbjct: 919 NDSLVQQVFNAAEIGSYTRIGYAPSSWIDDYFDWVKPQS-SCCRVYNTTGQFCNASVSDP 977
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
CT C + R F LP FLS P+ C KGGH AY
Sbjct: 978 ---------------SCTRCRPLTQEGKQRPQGEDFMTFLPMFLSDNPNPKCGKGGHAAY 1022
Query: 74 TSSVD 60
S+V+
Sbjct: 1023 NSAVN 1027
[104][TOP]
>UniRef100_UPI00017966B6 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Equus caballus
RepID=UPI00017966B6
Length = 1293
Score = 66.6 bits (161), Expect = 8e-10
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 932 NDSLVQQIFTAAQLDSYTRIGFAPSSWIDDYFDWVKPQS-SCCRVYNSTDQFC------- 983
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 984 -----NASVVDPACVRCRPLTPEGKQRPQGRDFMRF---LPMFLSDNPNPRCGKGGHAAY 1035
Query: 74 TSSVDLKGYDSAL 36
+S+V++ G D+ +
Sbjct: 1036 SSAVNILGNDTGV 1048
[105][TOP]
>UniRef100_Q9VRC9 NPC1b n=1 Tax=Drosophila melanogaster RepID=Q9VRC9_DROME
Length = 1254
Score = 66.6 bits (161), Expect = 8e-10
Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ + PE + +A+PA+SWLDD++ W++ CC+ T G +C + +
Sbjct: 896 NNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAIS--DCCKYNVTTGGFCSSNSKSE 953
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F + LR D + F +P+FL LP A+CAK G +Y
Sbjct: 954 DCLP------------CERGFTENGLRPDAET---FNKYIPYFLFDLPDAECAKAGRASY 998
Query: 74 TSSV 63
+V
Sbjct: 999 ADAV 1002
[106][TOP]
>UniRef100_B4R3B8 GD17503 n=1 Tax=Drosophila simulans RepID=B4R3B8_DROSI
Length = 1083
Score = 66.6 bits (161), Expect = 8e-10
Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ + PE + +A+PA+SWLDD++ W++ CC+ T G +C + +
Sbjct: 896 NNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAIS--DCCKYNVTTGGFCSSNSKSE 953
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F + LR D + F +P+FL LP A+CAK G +Y
Sbjct: 954 DCLP------------CERGFTENGLRPDAET---FNKYIPYFLFDLPDAECAKAGRASY 998
Query: 74 TSSV 63
+V
Sbjct: 999 ADAV 1002
[107][TOP]
>UniRef100_B4I6C1 GM23054 n=1 Tax=Drosophila sechellia RepID=B4I6C1_DROSE
Length = 1228
Score = 66.6 bits (161), Expect = 8e-10
Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ + PE + +A+PA+SWLDD++ W++ CC+ T G +C + +
Sbjct: 891 NNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAIS--DCCKYNVTTGGFCSSNSKSE 948
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F + LR D + F +P+FL LP A+CAK G +Y
Sbjct: 949 DCLP------------CERGFTENGLRPDAET---FNKYIPYFLFDLPDAECAKAGRASY 993
Query: 74 TSSV 63
+V
Sbjct: 994 ADAV 997
[108][TOP]
>UniRef100_B3NY50 GG19701 n=1 Tax=Drosophila erecta RepID=B3NY50_DROER
Length = 1248
Score = 66.6 bits (161), Expect = 8e-10
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S P+ + +A+PA+SWLDD++ W++ CC+ T G +C + +
Sbjct: 895 NNSLSVQLYTQSRYPQITALARPASSWLDDYIDWLAIS--DCCKYNITTGGFCSSNSKSE 952
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F LR D + F +P+FL LP A+CAK G +Y
Sbjct: 953 DCLP------------CERGFTEEGLRPDAET---FNKYIPYFLFDLPDAECAKAGRASY 997
Query: 74 TSSV 63
+V
Sbjct: 998 ADAV 1001
[109][TOP]
>UniRef100_B4M3Q5 GJ19256 n=1 Tax=Drosophila virilis RepID=B4M3Q5_DROVI
Length = 1254
Score = 66.2 bits (160), Expect = 1e-09
Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
+DSL ++ S P+ + +A+PA+SW+DD++ WI CC+ T G +CP + +
Sbjct: 888 NDSLSVQLYTQSRYPQITALARPASSWIDDYIDWIG--ISDCCKINATTGGFCPSNSK-- 943
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+DC C R R + F +P FLS LP A+CAK G +Y
Sbjct: 944 -------------SEDCYPCERQFTEDGLRPTPETFDKYVPIFLSDLPDAECAKAGRPSY 990
Query: 74 TSSV 63
+V
Sbjct: 991 ADAV 994
[110][TOP]
>UniRef100_UPI0000DB7411 PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA n=1 Tax=Apis
mellifera RepID=UPI0000DB7411
Length = 1238
Score = 65.9 bits (159), Expect = 1e-09
Identities = 42/127 (33%), Positives = 60/127 (47%), Gaps = 1/127 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
S+SL +I AS SY++K A+SWLDD++ W + CC+ F N S+CP
Sbjct: 902 SNSLYTQIYSASKQSAVSYLSKAASSWLDDYIDW--SQISDCCKYFKANESFCPHSQFEG 959
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C +CK T + +R FR LP+FL +P CAK G AY
Sbjct: 960 C----------DSCKINITDY-------NRPIAYDFRKYLPYFLQDIPDERCAKAGRAAY 1002
Query: 74 TSSVDLK 54
+++ K
Sbjct: 1003 FDALNYK 1009
[111][TOP]
>UniRef100_Q8MI49 Mutant Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MI49_FELCA
Length = 1276
Score = 65.9 bits (159), Expect = 1e-09
Identities = 39/132 (29%), Positives = 63/132 (47%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
+DSL+ +I A+ + + I +SW+DD+ W+ P++ C + +C
Sbjct: 915 NDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSSCRVYNSTDRFC-------- 966
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+ S V AC C + R M+F LP FLS P+ C KGGH AY+
Sbjct: 967 ----NASVVDPACIRCRPLTQEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAYS 1019
Query: 71 SSVDLKGYDSAL 36
S+V++ G D+ +
Sbjct: 1020 SAVNILGNDTGV 1031
[112][TOP]
>UniRef100_B4MSW0 GK19822 n=1 Tax=Drosophila willistoni RepID=B4MSW0_DROWI
Length = 1264
Score = 65.9 bits (159), Expect = 1e-09
Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S PE + +A+PA+SW+DD++ W++ CC+ T G +C + +
Sbjct: 907 NNSLSVQLYTQSRYPEITALARPASSWIDDYIDWLA--ISDCCKYNVTTGGFCASNSKSE 964
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F LR D + F + +FL LP A+CAK G AY
Sbjct: 965 DCLP------------CERSFTEDGLRPDEAT---FNKYVSYFLFDLPDAECAKAGRAAY 1009
Query: 74 TSSV 63
+V
Sbjct: 1010 ADAV 1013
[113][TOP]
>UniRef100_B3N938 GG23970 n=1 Tax=Drosophila erecta RepID=B3N938_DROER
Length = 1268
Score = 65.9 bits (159), Expect = 1e-09
Identities = 44/126 (34%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVW-ISPEAFGCCR-KFTNGSYCPPDDQPP 255
DS+L +I AS +YIA+PA+SW+DDF W + P CC+ K +G +CP D
Sbjct: 900 DSVLTQIYLASRHSNQTYIARPASSWIDDFFDWTVVP---SCCKYKKDSGDFCPHKD--- 953
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHG 81
T+C R + +N R +F LP+FL P CAK GH
Sbjct: 954 -----------------TSCLRCNISKNSLLRPEEKEFEKYLPFFLKDNPDDLCAKAGHA 996
Query: 80 AYTSSV 63
AY +V
Sbjct: 997 AYGGAV 1002
[114][TOP]
>UniRef100_UPI0001924FA3 PREDICTED: similar to predicted protein, partial n=1 Tax=Hydra
magnipapillata RepID=UPI0001924FA3
Length = 1289
Score = 65.1 bits (157), Expect = 2e-09
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 16/158 (10%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR--------KFTNGSYCP 273
+S++ I SL+ S IA PA+SW+DD+ W+ P A CCR K N S
Sbjct: 915 NSVVETIFVNSLMSNYSTIALPASSWIDDYFAWLDP-AGPCCRILNYTVSEKIVNSSIIE 973
Query: 272 PDDQPPCCAPEDDSCVSGACK--DCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADC 99
+ + C S A +C TC S R QF L W+L P+ C
Sbjct: 974 LKN----FSGSGQFCSSSAPDSWNCYTCLNKSQA-GLRPEPTQFDQYLEWYLKDNPTQKC 1028
Query: 98 AKGGHGAYTSSVDLKG------YDSALFKHHRSVHITP 3
KGGH AY S+V L +S+ F + +V TP
Sbjct: 1029 PKGGHAAYGSAVKLNSPKHKFRVNSSYFMTYHTVASTP 1066
[115][TOP]
>UniRef100_UPI0000DB761D PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA isoform 2 n=1
Tax=Apis mellifera RepID=UPI0000DB761D
Length = 1358
Score = 65.1 bits (157), Expect = 2e-09
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKF-TNGSYCPPDDQPP 255
SDS+ +I AS +YIAKPA+SWLDD++ W + CC+ F +N S+CP
Sbjct: 910 SDSVSTQIFIASKQSNRTYIAKPASSWLDDYIDW--SQLSTCCKYFMSNNSFCPH----- 962
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRND--RTSTMQFRDKLPWFLSALPSADCAKGGHG 81
+G+ K C++C + RN+ R F + +FL P CAK GH
Sbjct: 963 ----------TGSLKYCSSC---NITRNEIGRPIPTDFDRYVSFFLQDNPDDTCAKAGHA 1009
Query: 80 AYTSSVD 60
AY V+
Sbjct: 1010 AYGHGVN 1016
[116][TOP]
>UniRef100_B4M8H0 GJ18108 n=1 Tax=Drosophila virilis RepID=B4M8H0_DROVI
Length = 1282
Score = 65.1 bits (157), Expect = 2e-09
Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 7/145 (4%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DS+L ++ AS +YIA+PA+SW+DD+ W + CC+ N S+CP D
Sbjct: 915 DSVLTQLYLASRRSNLTYIARPASSWIDDYFDWALSSS--CCKYNPKNDSFCPHQDT--- 969
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+C +C + +DL+ R F LP+FL P C K GH AY+
Sbjct: 970 -----------SCSNC--IIKKNDLQ--RPDEQDFGKYLPFFLKDNPDDSCVKAGHAAYS 1014
Query: 71 SSVDLK------GYDSALFKHHRSV 15
+V DS+ F + S+
Sbjct: 1015 GAVRYNYAQKTLNVDSSYFMAYHSI 1039
[117][TOP]
>UniRef100_B3N0K3 GF21705 n=1 Tax=Drosophila ananassae RepID=B3N0K3_DROAN
Length = 1323
Score = 65.1 bits (157), Expect = 2e-09
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S PE + +A+PAASWLDD++ W++ CC+ T +C + +
Sbjct: 882 NNSLSVQLYTQSRYPEITSLARPAASWLDDYIDWLA--ISDCCKYNVTTLGFCSSNSKSD 939
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F + LR D + F +P+FL LP A+CAK G +Y
Sbjct: 940 DCLP------------CERTFTENGLRPDAET---FSKYIPFFLFDLPDAECAKAGRASY 984
Query: 74 TSSV 63
+V
Sbjct: 985 ADAV 988
[118][TOP]
>UniRef100_UPI00001830DD Cdig2 protein n=1 Tax=Rattus norvegicus RepID=UPI00001830DD
Length = 1278
Score = 64.7 bits (156), Expect = 3e-09
Identities = 39/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + + +SW+DD+ W+SP++ CCR + +C
Sbjct: 917 NDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQS-SCCRLYNVTHQFC------- 968
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S + C C R M+F LP FLS P+ C KGGH AY
Sbjct: 969 -----NASVIDPTCVRCRPLTPEGKQRPQGKEFMKF---LPMFLSDNPNPKCGKGGHAAY 1020
Query: 74 TSSVDLKGYDS 42
+S+V++ G D+
Sbjct: 1021 SSAVNIMGDDT 1031
[119][TOP]
>UniRef100_B7Q350 Niemann-Pick type C1 domain-containing protein, putative n=1
Tax=Ixodes scapularis RepID=B7Q350_IXOSC
Length = 1626
Score = 64.3 bits (155), Expect = 4e-09
Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPC 252
DSL+++I AS+ + I++PA SWLDD++ W + CCR T +CP +
Sbjct: 847 DSLVSQIQLASIYSNVTTISQPAQSWLDDYISWSGTQ--DCCRMNATTKQFCPRHENTTG 904
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
C SC+S R F LP FL +P C KGGH AY+
Sbjct: 905 CV----SCLS------------DQKTMSRPLGETFSRFLPDFLDDVPDPKCPKGGHAAYS 948
Query: 71 SSVDL 57
++V L
Sbjct: 949 NAVQL 953
[120][TOP]
>UniRef100_P56941 Niemann-Pick C1 protein n=1 Tax=Sus scrofa RepID=NPC1_PIG
Length = 1277
Score = 64.3 bits (155), Expect = 4e-09
Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ WI P++ CCR + + +C
Sbjct: 916 NDSLVQQIFTAAQLDNYTRIGFAPSSWIDDYFDWIKPQS-SCCRVYNSTDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V C C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPTCIRCRPLTSEGKQRPQGEDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDSAL 36
+S+V++ G S +
Sbjct: 1020 SSAVNILGNGSGV 1032
[121][TOP]
>UniRef100_UPI0001924FA4 PREDICTED: similar to predicted protein n=1 Tax=Hydra
magnipapillata RepID=UPI0001924FA4
Length = 920
Score = 63.9 bits (154), Expect = 5e-09
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR--------KFTNGSYCP 273
+S++ I SL+ S IA PA+SW+DD+ W+ P A CCR K N S
Sbjct: 528 NSVVETIFVNSLMSNYSTIALPASSWIDDYFAWLDP-AGPCCRILNYTVSEKIVNSSIIE 586
Query: 272 PDDQPPCCAPEDDSCVSGACK--DCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADC 99
+ + C S A +C TC S R QF L W+L P+ C
Sbjct: 587 LKN----FSGSGQFCSSSAPDSWNCYTCLNKSQA-GLRPEPTQFDQYLEWYLKDNPTQKC 641
Query: 98 AKGGHGAYTSSVDL 57
+KGGH AY S+V L
Sbjct: 642 SKGGHAAYGSAVKL 655
[122][TOP]
>UniRef100_UPI00005638CC Niemann Pick type C1 n=1 Tax=Mus musculus RepID=UPI00005638CC
Length = 1277
Score = 63.9 bits (154), Expect = 5e-09
Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + + +SW+DD+ W+SP++ CCR + +C P
Sbjct: 916 NDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQS-SCCRLYNVTHQFCNASVMDP 974
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C C+ T + R +F LP FLS P+ C KGGH AY
Sbjct: 975 TCV---------RCRPLTPEGKQ------RPQGKEFMKFLPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDS 42
S+V++ G D+
Sbjct: 1020 GSAVNIVGDDT 1030
[123][TOP]
>UniRef100_Q7TMD4 Niemann Pick type C1 n=1 Tax=Mus musculus RepID=Q7TMD4_MOUSE
Length = 1277
Score = 63.9 bits (154), Expect = 5e-09
Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + + +SW+DD+ W+SP++ CCR + +C P
Sbjct: 916 NDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQS-SCCRLYNVTHQFCNASVMDP 974
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C C+ T + R +F LP FLS P+ C KGGH AY
Sbjct: 975 TCV---------RCRPLTPEGKQ------RPQGKEFMKFLPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDS 42
S+V++ G D+
Sbjct: 1020 GSAVNIVGDDT 1030
[124][TOP]
>UniRef100_Q3U2B2 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q3U2B2_MOUSE
Length = 1094
Score = 63.9 bits (154), Expect = 5e-09
Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + + +SW+DD+ W+SP++ CCR + +C P
Sbjct: 916 NDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQS-SCCRLYNVTHQFCNASVMDP 974
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C C+ T + R +F LP FLS P+ C KGGH AY
Sbjct: 975 TCV---------RCRPLTPEGKQ------RPQGKEFMKFLPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDS 42
S+V++ G D+
Sbjct: 1020 GSAVNIVGDDT 1030
[125][TOP]
>UniRef100_O35604 Niemann-Pick C1 protein n=1 Tax=Mus musculus RepID=NPC1_MOUSE
Length = 1278
Score = 63.9 bits (154), Expect = 5e-09
Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + + +SW+DD+ W+SP++ CCR + +C P
Sbjct: 917 NDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQS-SCCRLYNVTHQFCNASVMDP 975
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C C+ T + R +F LP FLS P+ C KGGH AY
Sbjct: 976 TCV---------RCRPLTPEGKQ------RPQGKEFMKFLPMFLSDNPNPKCGKGGHAAY 1020
Query: 74 TSSVDLKGYDS 42
S+V++ G D+
Sbjct: 1021 GSAVNIVGDDT 1031
[126][TOP]
>UniRef100_UPI000069EB67 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB67
Length = 1283
Score = 63.5 bits (153), Expect = 7e-09
Identities = 42/125 (33%), Positives = 63/125 (50%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ EI A+ + + I +SW+DD+ W+ P++ CCR + N DQ
Sbjct: 922 NNSLVQEIYTAAGISNYTRIGYAPSSWIDDYFDWVKPQST-CCRIYNN------TDQFCN 974
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+ + SC+S C+ T + + D F LP FLS P+ C KGGH AY
Sbjct: 975 ASVVNASCLS--CRSYTPEGKRKPVGED------FMHFLPMFLSDNPNPKCGKGGHAAYG 1026
Query: 71 SSVDL 57
S+VDL
Sbjct: 1027 SAVDL 1031
[127][TOP]
>UniRef100_UPI000069EB66 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB66
Length = 1289
Score = 63.5 bits (153), Expect = 7e-09
Identities = 42/125 (33%), Positives = 63/125 (50%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ EI A+ + + I +SW+DD+ W+ P++ CCR + N DQ
Sbjct: 928 NNSLVQEIYTAAGISNYTRIGYAPSSWIDDYFDWVKPQST-CCRIYNN------TDQFCN 980
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+ + SC+S C+ T + + D F LP FLS P+ C KGGH AY
Sbjct: 981 ASVVNASCLS--CRSYTPEGKRKPVGED------FMHFLPMFLSDNPNPKCGKGGHAAYG 1032
Query: 71 SSVDL 57
S+VDL
Sbjct: 1033 SAVDL 1037
[128][TOP]
>UniRef100_UPI000069EB65 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB65
Length = 1282
Score = 63.5 bits (153), Expect = 7e-09
Identities = 42/125 (33%), Positives = 63/125 (50%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ EI A+ + + I +SW+DD+ W+ P++ CCR + N DQ
Sbjct: 921 NNSLVQEIYTAAGISNYTRIGYAPSSWIDDYFDWVKPQST-CCRIYNN------TDQFCN 973
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+ + SC+S C+ T + + D F LP FLS P+ C KGGH AY
Sbjct: 974 ASVVNASCLS--CRSYTPEGKRKPVGED------FMHFLPMFLSDNPNPKCGKGGHAAYG 1025
Query: 71 SSVDL 57
S+VDL
Sbjct: 1026 SAVDL 1030
[129][TOP]
>UniRef100_UPI000069EB64 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB64
Length = 1280
Score = 63.5 bits (153), Expect = 7e-09
Identities = 42/125 (33%), Positives = 63/125 (50%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPC 252
++SL+ EI A+ + + I +SW+DD+ W+ P++ CCR + N DQ
Sbjct: 919 NNSLVQEIYTAAGISNYTRIGYAPSSWIDDYFDWVKPQST-CCRIYNN------TDQFCN 971
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
+ + SC+S C+ T + + D F LP FLS P+ C KGGH AY
Sbjct: 972 ASVVNASCLS--CRSYTPEGKRKPVGED------FMHFLPMFLSDNPNPKCGKGGHAAYG 1023
Query: 71 SSVDL 57
S+VDL
Sbjct: 1024 SAVDL 1028
[130][TOP]
>UniRef100_Q4PE83 Putative uncharacterized protein n=1 Tax=Ustilago maydis
RepID=Q4PE83_USTMA
Length = 1489
Score = 63.5 bits (153), Expect = 7e-09
Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 12/136 (8%)
Frame = -2
Query: 389 PETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGS-YCPPDDQPPCCAPEDDSCVSGA 216
PE S+IA+PA+SW+DDFL W++P GCCR K ++ + +C P D P C P
Sbjct: 1108 PEVSWIAEPASSWIDDFLQWLNPILDGCCRVKISDPTVFCDPHDSPFSCQP--------- 1158
Query: 215 CKDCTTCFRHSD-----LRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSSVDL-- 57
CF D + +F L +L + +C GG AY+S++ +
Sbjct: 1159 ------CFEGRDPPWNITMDGLPEGQEFYRYLRKWLESPTDQECPLGGQAAYSSALSIVT 1212
Query: 56 ---KGYDSALFKHHRS 18
G D H R+
Sbjct: 1213 DLETGKDRVRSSHFRT 1228
[131][TOP]
>UniRef100_Q9JLG3 Niemann-Pick type C1 protein n=1 Tax=Cricetulus griseus
RepID=Q9JLG3_CRIGR
Length = 1277
Score = 63.2 bits (152), Expect = 9e-09
Identities = 39/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W++P++ CCR + +C
Sbjct: 916 NDSLVQQIFNAAELDNYTRIGFAPSSWIDDYFDWVAPQS-SCCRLYNATHQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S + C C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVIDPTCIRCRPLTPEGKQRPQGKEFMKF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKGYDS 42
+S+V++ G D+
Sbjct: 1020 SSAVNIIGDDT 1030
[132][TOP]
>UniRef100_Q29GK5 GA11389 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=Q29GK5_DROPS
Length = 1248
Score = 62.8 bits (151), Expect = 1e-08
Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S PE + +A+PA+SWLDD++ W++ CC+ T +C + +
Sbjct: 891 NNSLSVQLYTQSRYPEITSLARPASSWLDDYIDWLA--IVDCCKYNTTTQGFCSSNSKSD 948
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F LR S F LP+FL LP A+CAK G +Y
Sbjct: 949 DCLP------------CEREFTEDGLR---PSPETFSKYLPYFLFDLPDAECAKAGRASY 993
Query: 74 TSSV 63
+V
Sbjct: 994 ADAV 997
[133][TOP]
>UniRef100_B4H144 GL15811 n=1 Tax=Drosophila persimilis RepID=B4H144_DROPE
Length = 1250
Score = 62.8 bits (151), Expect = 1e-08
Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
++SL ++ S PE + +A+PA+SWLDD++ W++ CC+ T +C + +
Sbjct: 893 NNSLSVQLYTQSRYPEITSLARPASSWLDDYIDWLA--IVDCCKYNTTTQGFCSSNSKSD 950
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
C P C F LR S F LP+FL LP A+CAK G +Y
Sbjct: 951 DCLP------------CEREFTEDGLR---PSPETFSKYLPYFLFDLPDAECAKAGRASY 995
Query: 74 TSSV 63
+V
Sbjct: 996 ADAV 999
[134][TOP]
>UniRef100_UPI0000E24CB6 PREDICTED: Niemann-Pick disease, type C1 isoform 5 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB6
Length = 1217
Score = 62.0 bits (149), Expect = 2e-08
Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 916 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKG 51
+S+V++ G
Sbjct: 1020 SSAVNILG 1027
[135][TOP]
>UniRef100_UPI0000E24CB5 PREDICTED: Niemann-Pick disease, type C1 isoform 2 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB5
Length = 1261
Score = 62.0 bits (149), Expect = 2e-08
Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 916 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKG 51
+S+V++ G
Sbjct: 1020 SSAVNILG 1027
[136][TOP]
>UniRef100_UPI0000E24CB3 PREDICTED: Niemann-Pick disease, type C1 isoform 1 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB3
Length = 1285
Score = 62.0 bits (149), Expect = 2e-08
Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 916 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKG 51
+S+V++ G
Sbjct: 1020 SSAVNILG 1027
[137][TOP]
>UniRef100_UPI000036A3B7 PREDICTED: Niemann-Pick disease, type C1 isoform 4 n=2 Tax=Pan
troglodytes RepID=UPI000036A3B7
Length = 1277
Score = 62.0 bits (149), Expect = 2e-08
Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 916 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDLKG 51
+S+V++ G
Sbjct: 1020 SSAVNILG 1027
[138][TOP]
>UniRef100_UPI00016E1F22 UPI00016E1F22 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F22
Length = 1297
Score = 61.6 bits (148), Expect = 3e-08
Identities = 43/125 (34%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN----GSYCPPDDQP 258
SL +I A+ + SYI P+ SW+DDF+ W++P A CCR +T G +CP +
Sbjct: 930 SLTQKIQYATDYSQLSYIGIPSNSWVDDFIDWLNP-ASRCCRLYTTGQNFGKFCPASEP- 987
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
A K C S R S QF L FL P C KGG GA
Sbjct: 988 -------------ATKCLLKCMNPSLDGVLRPSVSQFNRYLTDFLGNRPDLQCPKGGLGA 1034
Query: 77 YTSSV 63
Y +V
Sbjct: 1035 YDKAV 1039
[139][TOP]
>UniRef100_UPI00016E1F21 UPI00016E1F21 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F21
Length = 1289
Score = 61.6 bits (148), Expect = 3e-08
Identities = 43/125 (34%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN----GSYCPPDDQP 258
SL +I A+ + SYI P+ SW+DDF+ W++P A CCR +T G +CP +
Sbjct: 924 SLTQKIQYATDYSQLSYIGIPSNSWVDDFIDWLNP-ASRCCRLYTTGQNFGKFCPASEP- 981
Query: 257 PCCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGA 78
A K C S R S QF L FL P C KGG GA
Sbjct: 982 -------------ATKCLLKCMNPSLDGVLRPSVSQFNRYLTDFLGNRPDLQCPKGGLGA 1028
Query: 77 YTSSV 63
Y +V
Sbjct: 1029 YDKAV 1033
[140][TOP]
>UniRef100_Q9TT75 Niemann-Pick type C1 disease protein n=1 Tax=Oryctolagus cuniculus
RepID=Q9TT75_RABIT
Length = 1286
Score = 60.5 bits (145), Expect = 6e-08
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 925 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVSNVTEQFC------- 976
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 977 -----NASVVDPACVRCRPLTPEGKQRPQGEDFMRF---LPMFLSDNPNPKCGKGGHAAY 1028
Query: 74 TSSVDLKG 51
++V++ G
Sbjct: 1029 GTAVNILG 1036
[141][TOP]
>UniRef100_Q59GR1 Niemann-Pick disease, type C1 variant (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GR1_HUMAN
Length = 1289
Score = 60.5 bits (145), Expect = 6e-08
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 927 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 978
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 979 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1030
Query: 74 TSSVDL 57
+S+V++
Sbjct: 1031 SSAVNI 1036
[142][TOP]
>UniRef100_B4DET3 cDNA FLJ51802, highly similar to Niemann-Pick C1 protein n=1
Tax=Homo sapiens RepID=B4DET3_HUMAN
Length = 960
Score = 60.5 bits (145), Expect = 6e-08
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 598 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 649
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 650 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 701
Query: 74 TSSVDL 57
+S+V++
Sbjct: 702 SSAVNI 707
[143][TOP]
>UniRef100_Q5KGS9 Vacuolar membrane protein, putative n=1 Tax=Filobasidiella neoformans
RepID=Q5KGS9_CRYNE
Length = 1330
Score = 60.5 bits (145), Expect = 6e-08
Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCC--RKFTNGSYCPPDDQPPC 252
S+ N + P++S+IA P A+W+DDFL W +P CC R+ +C P D
Sbjct: 951 SVANTLEAERKRPDSSFIASPPAAWIDDFLQWTNPTFESCCRVRRRDPTIFCSPKDSERL 1010
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
C P C G D T D + M++ ++ W +S + +C GG Y+
Sbjct: 1011 CRP----CFEGQKWDST-----MDGLPEGEDFMRYLEQ--WLISP-TNDECPLGGQAPYS 1058
Query: 71 SSVDLKGYDSALFKHHRSVHITP 3
++V L ++ + H + TP
Sbjct: 1059 AAVKLVSSNTTVAASHFRTYHTP 1081
[144][TOP]
>UniRef100_Q55SD4 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
RepID=Q55SD4_CRYNE
Length = 1330
Score = 60.5 bits (145), Expect = 6e-08
Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCC--RKFTNGSYCPPDDQPPC 252
S+ N + P++S+IA P A+W+DDFL W +P CC R+ +C P D
Sbjct: 951 SVANTLEAERKRPDSSFIASPPAAWIDDFLQWTNPTFESCCRVRRRDPTIFCSPKDSERL 1010
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
C P C G D T D + M++ ++ W +S + +C GG Y+
Sbjct: 1011 CRP----CFEGQKWDST-----MDGLPEGEDFMRYLEQ--WLISP-TNDECPLGGQAPYS 1058
Query: 71 SSVDLKGYDSALFKHHRSVHITP 3
++V L ++ + H + TP
Sbjct: 1059 AAVKLVSSNTTVAASHFRTYHTP 1081
[145][TOP]
>UniRef100_O15118 Niemann-Pick C1 protein n=1 Tax=Homo sapiens RepID=NPC1_HUMAN
Length = 1278
Score = 60.5 bits (145), Expect = 6e-08
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFT-NGSYCPPDDQPP 255
+DSL+ +I A+ + + I +SW+DD+ W+ P++ CCR +C
Sbjct: 916 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQS-SCCRVDNITDQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V AC C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVDPACVRCRPLTPEGKQRPQGGDFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDL 57
+S+V++
Sbjct: 1020 SSAVNI 1025
[146][TOP]
>UniRef100_B0JYK2 NPC1 protein n=2 Tax=Bos taurus RepID=B0JYK2_BOVIN
Length = 1277
Score = 60.1 bits (144), Expect = 8e-08
Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGS-YCPPDDQPP 255
+DSL+ ++ A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 916 NDSLVQQVFTAAQLDSYTRIGFAPSSWIDDYFDWVKPQS-SCCRIYNSTEQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V+ C C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVNPTCVRCRPLTPEGKQRPQGADFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDL 57
+++V++
Sbjct: 1020 SAAVNI 1025
[147][TOP]
>UniRef100_Q9GLC9 Niemann-Pick type C1 disease protein n=1 Tax=Bos taurus
RepID=Q9GLC9_BOVIN
Length = 1277
Score = 60.1 bits (144), Expect = 8e-08
Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGS-YCPPDDQPP 255
+DSL+ ++ A+ + + I +SW+DD+ W+ P++ CCR + + +C
Sbjct: 916 NDSLVQQVFTAAQLDSYTRIGFAPSSWIDDYFDWVKPQS-SCCRIYNSTEQFC------- 967
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V+ C C R M+F LP FLS P+ C KGGH AY
Sbjct: 968 -----NASVVNPTCVRCRPLTPEGKQRPQGADFMRF---LPMFLSDNPNPKCGKGGHAAY 1019
Query: 74 TSSVDL 57
+++V++
Sbjct: 1020 SAAVNI 1025
[148][TOP]
>UniRef100_UPI0000F2C55D PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2C55D
Length = 1280
Score = 59.7 bits (143), Expect = 1e-07
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = -2
Query: 431 SDSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTN-GSYCPPDDQPP 255
++SL+ +I A+ + + I +SW+DD+ WI P++ CCR + +C
Sbjct: 919 NNSLVQQIFNAAELDNYTRIGFAPSSWIDDYFDWIKPQS-SCCRIYNRTDKFC------- 970
Query: 254 CCAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAY 75
+ S V +C C R M+F LP FLS P+ C KGGH AY
Sbjct: 971 -----NASVVDPSCVRCRPLTPEGKRRPQGEDFMKF---LPMFLSDNPNPKCGKGGHAAY 1022
Query: 74 TSSVDL 57
+S+V L
Sbjct: 1023 SSAVHL 1028
[149][TOP]
>UniRef100_A8NWN7 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NWN7_COPC7
Length = 1382
Score = 58.9 bits (141), Expect = 2e-07
Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 3/129 (2%)
Frame = -2
Query: 389 PETSYIAKPAASWLDDFLVWISPEAFGCC--RKFTNGSYCPPDDQPPCCAPEDDSCVSGA 216
PE+S+I++PAASW+D+FL W+ P CC RK +C P+D C P C+ A
Sbjct: 1015 PESSFISQPAASWIDEFLGWLDPAKDQCCRVRKRNPNVFCRPNDMGRMCRP----CL--A 1068
Query: 215 CKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTSSVDLKGYDSAL 36
++ D +F L +LS+ PS +C GG ++ +S+ + + +
Sbjct: 1069 DREPPYNISMDGFPEDE----EFVRYLKHWLSSPPSQECPLGGKASFGASLSIDEENGLV 1124
Query: 35 -FKHHRSVH 12
H R+ H
Sbjct: 1125 TASHFRTFH 1133
[150][TOP]
>UniRef100_A7TSK4 Putative uncharacterized protein (Fragment) n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TSK4_VANPO
Length = 826
Score = 56.6 bits (135), Expect = 8e-07
Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Frame = -2
Query: 386 ETSYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPCCAPEDDSCVSGACK 210
E S I +P A+W DDF+ +++PE CCR K CPP+ P +
Sbjct: 494 ERSTITEPLANWYDDFMTFLNPELDTCCRVKKGTTETCPPEFSP---------------R 538
Query: 209 DCTTCFRHSDLRNDRTSTMQFRDKLPWFLSAL--PSADCAKGGHGAYTSSVDLKGYDSAL 36
C TCF+ D D T + D + +F + PS C GG Y+ +V DS +
Sbjct: 539 LCETCFKDKDWDYDMTGFPEGNDFMKYFKIWIESPSDPCPLGGKAPYSHAVSYN--DSTI 596
Query: 35 FKH-HRSVH 12
RS H
Sbjct: 597 ISSVFRSAH 605
[151][TOP]
>UniRef100_B0CUV0 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
RepID=B0CUV0_LACBS
Length = 1341
Score = 55.1 bits (131), Expect = 2e-06
Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 2/140 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCC--RKFTNGSYCPPDDQPPC 252
S+ N + PE+S+I++P ASW+DDFL W+ P CC RK +C D
Sbjct: 962 SVPNRLEGERKRPESSFISEPTASWIDDFLGWLDPGKEECCRVRKADPSVFCRERDPARL 1021
Query: 251 CAPEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYT 72
C P C G K+ L D R W++S + +C G ++
Sbjct: 1022 CRP----CYEG--KEPAWNITMDGLPEDGEFMRYLRQ---WWISP-TTEECPLAGKASFG 1071
Query: 71 SSVDLKGYDSALFKHHRSVH 12
+++ L DS + H R+ H
Sbjct: 1072 TALSLDS-DSVVASHFRTFH 1090
[152][TOP]
>UniRef100_A3GGU6 Predicted protein n=1 Tax=Pichia stipitis RepID=A3GGU6_PICST
Length = 1268
Score = 55.1 bits (131), Expect = 2e-06
Identities = 41/143 (28%), Positives = 65/143 (45%), Gaps = 5/143 (3%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCCA 246
SL N + K S I++PA++WLDDF W++P+ CCR + +P CA
Sbjct: 883 SLANILEKEYKRGFKSTISEPASNWLDDFFTWLNPDLDQCCRFKKTSVF----GEPEFCA 938
Query: 245 PEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQF---RDKLPWFLSAL--PSADCAKGGHG 81
P + C TC+ + D D +S F +D + +F + PS C GG
Sbjct: 939 PHAPD------RQCQTCYENHDPPYD-SSMKGFPTDKDFMFYFNHWIEEPSDPCPLGGKA 991
Query: 80 AYTSSVDLKGYDSALFKHHRSVH 12
Y+SS+ + + + R+ H
Sbjct: 992 PYSSSIS-RNESKVISSYFRTSH 1013
[153][TOP]
>UniRef100_UPI00003BD942 hypothetical protein DEHA0D05335g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BD942
Length = 1264
Score = 54.7 bits (130), Expect = 3e-06
Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
Frame = -2
Query: 425 SLLNEISKASLVPET------SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDD 264
S NE S ++++ + S IA+PA+SWLDDFL W++P+ CCR N P D
Sbjct: 891 STCNEFSVSNILEQELKRSSKSTIAEPASSWLDDFLTWLNPDLDQCCRFKKNS----PFD 946
Query: 263 QPPCCAPEDDSCVSGACKDCTTCF--RHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKG 90
C P S C+ C T ++S+ + +F ++ PS C G
Sbjct: 947 DKQFCTP---STPERLCEACYTDHDPQYSNTMEGFPTGKEFMFYFNQWIEE-PSDPCPLG 1002
Query: 89 GHGAYTSSVDL----KGYDSALFKHHRS 18
G Y++S+ + DS+ F+ S
Sbjct: 1003 GKAPYSTSISVNRNKSKIDSSYFRSSHS 1030
[154][TOP]
>UniRef100_Q6BT03 DEHA2D04620p n=1 Tax=Debaryomyces hansenii RepID=Q6BT03_DEBHA
Length = 1264
Score = 54.7 bits (130), Expect = 3e-06
Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
Frame = -2
Query: 425 SLLNEISKASLVPET------SYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDD 264
S NE S ++++ + S IA+PA+SWLDDFL W++P+ CCR N P D
Sbjct: 891 STCNEFSVSNILEQELKRSSKSTIAEPASSWLDDFLTWLNPDLDQCCRFKKNS----PFD 946
Query: 263 QPPCCAPEDDSCVSGACKDCTTCF--RHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKG 90
C P S C+ C T ++S+ + +F ++ PS C G
Sbjct: 947 DKQFCTP---STPERLCEACYTDHDPQYSNTMEGFPTGKEFMFYFNQWIEE-PSDPCPLG 1002
Query: 89 GHGAYTSSVDL----KGYDSALFKHHRS 18
G Y++S+ + DS+ F+ S
Sbjct: 1003 GKAPYSTSISVNRNKSKIDSSYFRSSHS 1030
[155][TOP]
>UniRef100_A4RE01 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4RE01_MAGGR
Length = 1275
Score = 54.7 bits (130), Expect = 3e-06
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
Frame = -2
Query: 425 SLLNEISKASLVPETSYIAKPAASWLDDFLVWISPE-AFGCCRKFTNGSYCPPDDQPPCC 249
S+ N + + PE SYIA P ASW+DDF +W+ P+ CC NG C D PP
Sbjct: 910 SMTNILEQERKRPEISYIASPTASWIDDFFLWLDPDLGESCC--VENGKACFADRNPPW- 966
Query: 248 APEDDSCVSGACKDCTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKGGHGAYTS 69
+SG K +F L F+ + + +C GG AY
Sbjct: 967 ----SITMSGMPKG-----------------QEFVHYLDKFIQSPTTEECPLGGQAAYGD 1005
Query: 68 SVDLKGYDSAL-FKHHRSVH 12
+V + + + H R++H
Sbjct: 1006 AVVIDHEKTTIGASHFRTMH 1025
[156][TOP]
>UniRef100_A7S0G1 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S0G1_NEMVE
Length = 1277
Score = 54.3 bits (129), Expect = 4e-06
Identities = 38/116 (32%), Positives = 50/116 (43%), Gaps = 3/116 (2%)
Frame = -2
Query: 428 DSLLNEISKASLVPETSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPPDDQPPCC 249
DSL+ ++ ASL S IA PA+SWLDD+ WI P CCR + P
Sbjct: 907 DSLIQQVFTASLRSNRSKIAMPASSWLDDYFNWIDPST-TCCRILYENT---TSGVVPAK 962
Query: 248 APEDDSCVSGACKD---CTTCFRHSDLRNDRTSTMQFRDKLPWFLSALPSADCAKG 90
P A C C S + +R + +F LP++L P CAKG
Sbjct: 963 GPNGGLVFCNATVKNDLCMPCMNKSQ-QGERPTPSEFDMYLPFYLKDNPELVCAKG 1017
[157][TOP]
>UniRef100_Q6FKT2 Similar to uniprot|Q12200 Saccharomyces cerevisiae YPL006w n=1
Tax=Candida glabrata RepID=Q6FKT2_CANGA
Length = 1193
Score = 53.1 bits (126), Expect = 9e-06
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 3/126 (2%)
Frame = -2
Query: 380 SYIAKPAASWLDDFLVWISPEAFGCCR-KFTNGSYCPPDDQPPCCAPEDDSCVSGACKDC 204
S + +P +WLDD+L +++PE CCR K CPP P + C
Sbjct: 868 STVTEPVTNWLDDYLSFLNPELDQCCRFKKGTNEICPPYFPP---------------RRC 912
Query: 203 TTCFRHSDLRNDRTSTMQFRDKLPWF--LSALPSADCAKGGHGAYTSSVDLKGYDSALFK 30
TC+ + ND T + + + +F PS +C GG Y++S+ + +
Sbjct: 913 ETCYSQGEWSNDMTGFPENGEFMKYFDIWINTPSDNCPLGGKAPYSNSISYND-STVISS 971
Query: 29 HHRSVH 12
RS H
Sbjct: 972 AFRSAH 977