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[1][TOP]
>UniRef100_B2DDA8 Topoisomerase I n=1 Tax=Catharanthus roseus RepID=B2DDA8_CATRO
Length = 910
Score = 166 bits (419), Expect = 1e-39
Identities = 79/90 (87%), Positives = 85/90 (94%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ E+LEKKI+QTNAKIEKM+RD +TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 821 DGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCK 880
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKFTWAMDVDP FRF
Sbjct: 881 RHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 910
[2][TOP]
>UniRef100_Q9FJ79 DNA topoisomerase I n=1 Tax=Arabidopsis thaliana RepID=Q9FJ79_ARATH
Length = 917
Score = 162 bits (409), Expect = 2e-38
Identities = 75/90 (83%), Positives = 84/90 (93%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK+K+NL+ EALEKKI QT KIEKM+RDM+TKED+ TVALGTSKINY+DPRITVAWCK
Sbjct: 822 DGKRKRNLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCK 881
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RH+VPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 882 RHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 911
[3][TOP]
>UniRef100_Q8RXI5 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RXI5_ARATH
Length = 232
Score = 162 bits (409), Expect = 2e-38
Identities = 75/90 (83%), Positives = 84/90 (93%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK+K+NL+ EALEKKI QT KIEKM+RDM+TKED+ TVALGTSKINY+DPRITVAWCK
Sbjct: 137 DGKRKRNLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCK 196
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RH+VPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 197 RHDVPIEKIFNKSLLAKFAWAMDVDPEFRF 226
[4][TOP]
>UniRef100_B9I1A0 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
RepID=B9I1A0_POPTR
Length = 860
Score = 161 bits (408), Expect = 2e-38
Identities = 77/90 (85%), Positives = 83/90 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK+K+NL+ EA+EKKI+ TN KIEKM+ MKTKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 771 DGKQKRNLTPEAIEKKIATTNQKIEKMELSMKTKEDLKTVALGTSKINYLDPRITVAWCK 830
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKFTWAMDVDP FRF
Sbjct: 831 RHEVPIEKIFNKSLLAKFTWAMDVDPQFRF 860
[5][TOP]
>UniRef100_UPI000198447D PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI000198447D
Length = 883
Score = 160 bits (405), Expect = 5e-38
Identities = 76/90 (84%), Positives = 82/90 (91%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK KKN++ E LE+KI+QTN KIEKM+RDMKTKEDL TVALGTSKINYLDPRI+VAWCK
Sbjct: 794 DGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCK 853
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
R EVPIEKIFNKSLLAKF WAMDVDP FRF
Sbjct: 854 RQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 883
[6][TOP]
>UniRef100_A7PX10 Chromosome chr12 scaffold_36, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7PX10_VITVI
Length = 789
Score = 160 bits (405), Expect = 5e-38
Identities = 76/90 (84%), Positives = 82/90 (91%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK KKN++ E LE+KI+QTN KIEKM+RDMKTKEDL TVALGTSKINYLDPRI+VAWCK
Sbjct: 700 DGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCK 759
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
R EVPIEKIFNKSLLAKF WAMDVDP FRF
Sbjct: 760 RQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 789
[7][TOP]
>UniRef100_B9SSQ1 DNA topoisomerase type I, putative n=1 Tax=Ricinus communis
RepID=B9SSQ1_RICCO
Length = 891
Score = 160 bits (404), Expect = 7e-38
Identities = 76/90 (84%), Positives = 83/90 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK+K+NLS E +EKKI+ TN +IEKM+ +MKTKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 802 DGKQKRNLSPENIEKKIASTNQRIEKMELNMKTKEDLKTVALGTSKINYLDPRITVAWCK 861
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKFTWAMDVDP FRF
Sbjct: 862 RHEVPIEKIFNKSLLAKFTWAMDVDPQFRF 891
[8][TOP]
>UniRef100_B2DDA6 Topoisomerase I n=1 Tax=Ophiorrhiza japonica RepID=B2DDA6_9GENT
Length = 927
Score = 159 bits (402), Expect = 1e-37
Identities = 75/90 (83%), Positives = 83/90 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ EALE+K++Q NAKIEKM+RD +TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 838 DGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCK 897
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKF W+MDVDP FRF
Sbjct: 898 RHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927
[9][TOP]
>UniRef100_B9GJH5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GJH5_POPTR
Length = 877
Score = 158 bits (399), Expect = 3e-37
Identities = 75/90 (83%), Positives = 83/90 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK+K++L+ EA+EKKI+ TN KIEKM+ MKTKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 788 DGKQKRSLTPEAIEKKIATTNQKIEKMEMAMKTKEDLKTVALGTSKINYLDPRITVAWCK 847
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPI+KIFNKSLLAKFTWAMDVDP FRF
Sbjct: 848 RHEVPIDKIFNKSLLAKFTWAMDVDPQFRF 877
[10][TOP]
>UniRef100_Q84ZL5 Os08g0154600 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q84ZL5_ORYSJ
Length = 916
Score = 157 bits (397), Expect = 5e-37
Identities = 75/90 (83%), Positives = 80/90 (88%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ EA EKKISQ KIEKM+ D K KEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 827 DGKPKRNLAPEAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 886
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSL+AKF+WAMDVDPDFRF
Sbjct: 887 RHEVPIEKIFNKSLIAKFSWAMDVDPDFRF 916
[11][TOP]
>UniRef100_A2YRB7 Putative uncharacterized protein n=1 Tax=Oryza sativa Indica Group
RepID=A2YRB7_ORYSI
Length = 916
Score = 157 bits (397), Expect = 5e-37
Identities = 75/90 (83%), Positives = 80/90 (88%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ EA EKKISQ KIEKM+ D K KEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 827 DGKPKRNLAPEAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 886
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSL+AKF+WAMDVDPDFRF
Sbjct: 887 RHEVPIEKIFNKSLIAKFSWAMDVDPDFRF 916
[12][TOP]
>UniRef100_Q9XGL1 DNA topoisomerase I n=1 Tax=Daucus carota RepID=Q9XGL1_DAUCA
Length = 909
Score = 157 bits (396), Expect = 6e-37
Identities = 73/90 (81%), Positives = 83/90 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+N++ EA+EKKI+QTN KIEKM+RD +TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 820 DGKTKRNMNPEAIEKKIAQTNVKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCK 879
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
R+EVPIEK+FNKSLLAKF WAMDV+P FRF
Sbjct: 880 RYEVPIEKMFNKSLLAKFAWAMDVEPSFRF 909
[13][TOP]
>UniRef100_B2DDA7 Topoisomerase I n=1 Tax=Camptotheca acuminata RepID=B2DDA7_CAMAC
Length = 894
Score = 157 bits (396), Expect = 6e-37
Identities = 73/90 (81%), Positives = 82/90 (91%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ EALE+KI QTNAKIEKM+RD +TKE L T+ALGTSKI+YLDPRITVAWCK
Sbjct: 805 DGKPKRNLTPEALERKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCK 864
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEK+FNKSLLAKF W+MDVDP FRF
Sbjct: 865 RHEVPIEKVFNKSLLAKFAWSMDVDPSFRF 894
[14][TOP]
>UniRef100_B2DDA5 Topoisomerase I n=1 Tax=Ophiorrhiza liukiuensis RepID=B2DDA5_9GENT
Length = 926
Score = 155 bits (392), Expect = 2e-36
Identities = 73/90 (81%), Positives = 82/90 (91%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DG+ K+NL+ E+LE+KI+QTNAKIEKM+RD KTKEDL VAL TSKI+YLDPRITVAWCK
Sbjct: 837 DGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCK 896
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKF W+MDVDP FRF
Sbjct: 897 RHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 926
[15][TOP]
>UniRef100_B2DDA4 Topoisomerase I n=1 Tax=Ophiorrhiza pumila RepID=B2DDA4_9GENT
Length = 926
Score = 153 bits (387), Expect = 7e-36
Identities = 73/90 (81%), Positives = 81/90 (90%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DG+ K+NL+ EALE+KI+QTNAKIEKM+RD KTKEDL VAL TSKI+YLDPRITVAWCK
Sbjct: 837 DGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCK 896
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
R EVPIEK+FNKSLLAKF WAMDVDP FRF
Sbjct: 897 RQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926
[16][TOP]
>UniRef100_C5YGY1 Putative uncharacterized protein Sb07g003610 n=1 Tax=Sorghum bicolor
RepID=C5YGY1_SORBI
Length = 921
Score = 152 bits (384), Expect = 1e-35
Identities = 71/90 (78%), Positives = 80/90 (88%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
+GK+K+NL+ EA+EKKI+ KI+KM+ D K KEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 832 EGKQKRNLAPEAIEKKIAMVEGKIDKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCK 891
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSL+AKF WAMDVDPDFRF
Sbjct: 892 RHEVPIEKIFNKSLIAKFGWAMDVDPDFRF 921
[17][TOP]
>UniRef100_A7QDA6 Chromosome undetermined scaffold_80, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7QDA6_VITVI
Length = 857
Score = 152 bits (384), Expect = 1e-35
Identities = 72/87 (82%), Positives = 80/87 (91%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
K++NL+ EALE+KI+QTNAKIEKM+RD TKEDL TVALGTSKINYLDPRI+VAWCKR E
Sbjct: 771 KRRNLTPEALERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQE 830
Query: 350 VPIEKIFNKSLLAKFTWAMDVDPDFRF 270
VPIEK+FNKSLLAKF WAMDV PDFRF
Sbjct: 831 VPIEKVFNKSLLAKFAWAMDVPPDFRF 857
[18][TOP]
>UniRef100_C6KE75 DNA topoisomerase I n=1 Tax=Zea mays RepID=C6KE75_MAIZE
Length = 904
Score = 149 bits (376), Expect = 1e-34
Identities = 69/90 (76%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
+GK K+NL+ EA++KK++ KIEKM+ D + KEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 815 EGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCK 874
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 875 RHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 904
[19][TOP]
>UniRef100_B7ZWU7 Putative uncharacterized protein n=1 Tax=Zea mays
RepID=B7ZWU7_MAIZE
Length = 574
Score = 149 bits (376), Expect = 1e-34
Identities = 69/90 (76%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
+GK K+NL+ EA++KK++ KIEKM+ D + KEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 485 EGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCK 544
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLLAKF WAMDVDP+FRF
Sbjct: 545 RHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 574
[20][TOP]
>UniRef100_Q8RX06 Putative DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=Q8RX06_ARATH
Length = 514
Score = 149 bits (375), Expect = 2e-34
Identities = 71/90 (78%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGKK ++L A EKKI+Q +AKIEKM+RDM TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 422 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 481
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIF KSLL KF WAMDV+P++RF
Sbjct: 482 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 511
[21][TOP]
>UniRef100_Q56XA9 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56XA9_ARATH
Length = 396
Score = 149 bits (375), Expect = 2e-34
Identities = 71/90 (78%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGKK ++L A EKKI+Q +AKIEKM+RDM TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 304 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 363
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIF KSLL KF WAMDV+P++RF
Sbjct: 364 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 393
[22][TOP]
>UniRef100_Q56X27 DNA topoisomerase I (Fragment) n=1 Tax=Arabidopsis thaliana
RepID=Q56X27_ARATH
Length = 270
Score = 149 bits (375), Expect = 2e-34
Identities = 71/90 (78%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGKK ++L A EKKI+Q +AKIEKM+RDM TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 178 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 237
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIF KSLL KF WAMDV+P++RF
Sbjct: 238 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 267
[23][TOP]
>UniRef100_P30181 DNA topoisomerase 1 n=1 Tax=Arabidopsis thaliana RepID=TOP1_ARATH
Length = 916
Score = 149 bits (375), Expect = 2e-34
Identities = 71/90 (78%), Positives = 79/90 (87%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGKK ++L A EKKI+Q +AKIEKM+RDM TKEDL TVALGTSKINYLDPRITVAWCK
Sbjct: 824 DGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 883
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIF KSLL KF WAMDV+P++RF
Sbjct: 884 RHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 913
[24][TOP]
>UniRef100_A9T368 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T368_PHYPA
Length = 502
Score = 147 bits (371), Expect = 5e-34
Identities = 68/90 (75%), Positives = 80/90 (88%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
+GK K+N + EALEKKI+ T KI+KM+ DM+ K+DL TVALGTSKINY+DPRITVAWCK
Sbjct: 413 EGKVKRNQTPEALEKKIASTTQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCK 472
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLL+KF WAM+V+PDFRF
Sbjct: 473 RHEVPIEKIFNKSLLSKFAWAMEVEPDFRF 502
[25][TOP]
>UniRef100_A9T3W2 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9T3W2_PHYPA
Length = 632
Score = 147 bits (370), Expect = 6e-34
Identities = 68/90 (75%), Positives = 80/90 (88%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
+GK K+N + EALEKKI+ T KI+KM+ DM+ K+DL TVALGTSKINY+DPRITVAWCK
Sbjct: 543 EGKVKRNQTPEALEKKIAATKQKIDKMRLDMRVKDDLKTVALGTSKINYMDPRITVAWCK 602
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RHEVPIEKIFNKSLL+KF WAM+V+PDFRF
Sbjct: 603 RHEVPIEKIFNKSLLSKFAWAMEVEPDFRF 632
[26][TOP]
>UniRef100_A5BM51 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BM51_VITVI
Length = 1449
Score = 147 bits (370), Expect = 6e-34
Identities = 72/90 (80%), Positives = 80/90 (88%), Gaps = 3/90 (3%)
Frame = -2
Query: 530 KKKNLSSEA---LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
K++NL+ EA LE+KI+QTNAKIEKM+RD TKEDL TVALGTSKINYLDPRI+VAWCK
Sbjct: 1360 KRRNLTPEATYRLERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCK 1419
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
R EVPIEK+FNKSLLAKF WAMDV PDFRF
Sbjct: 1420 RQEVPIEKVFNKSLLAKFAWAMDVPPDFRF 1449
[27][TOP]
>UniRef100_O24307 Topoisomerase I n=1 Tax=Pisum sativum RepID=O24307_PEA
Length = 892
Score = 133 bits (335), Expect(2) = 4e-32
Identities = 65/75 (86%), Positives = 69/75 (92%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K++L+ E LEKKISQTNAKIEKMQRDMKTK DL TVALGTSKINYLDPRITVAWCK
Sbjct: 798 DGKSKRSLTPEVLEKKISQTNAKIEKMQRDMKTKVDLKTVALGTSKINYLDPRITVAWCK 857
Query: 359 RHEVPIEKIFNKSLL 315
RHEVPIEK+F KSLL
Sbjct: 858 RHEVPIEKLFTKSLL 872
Score = 28.5 bits (62), Expect(2) = 4e-32
Identities = 15/26 (57%), Positives = 17/26 (65%)
Frame = -3
Query: 340 KRFSTSLCWPSSLGLWMWTLTSDSEI 263
K F+ SL + LG WMWT SDSEI
Sbjct: 865 KLFTKSLL-QNLLGQWMWTQISDSEI 889
[28][TOP]
>UniRef100_P93119 DNA topoisomerase 1 n=1 Tax=Daucus carota RepID=TOP1_DAUCA
Length = 790
Score = 134 bits (338), Expect = 3e-30
Identities = 65/79 (82%), Positives = 71/79 (89%)
Frame = -2
Query: 506 ALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 327
++ KKI+QTN KIEKM+RD +TKEDL TVALGTSKINYLDPRITVAWCKRH+VPIEKIFN
Sbjct: 712 SVTKKIAQTNTKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFN 771
Query: 326 KSLLAKFTWAMDVDPDFRF 270
KSLLAKF WAMDV FRF
Sbjct: 772 KSLLAKFAWAMDVVLIFRF 790
[29][TOP]
>UniRef100_B3H4K2 Uncharacterized protein At4g26701.1 n=1 Tax=Arabidopsis thaliana
RepID=B3H4K2_ARATH
Length = 69
Score = 125 bits (315), Expect = 1e-27
Identities = 58/68 (85%), Positives = 62/68 (91%)
Frame = -2
Query: 473 KIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 294
KIEKM+RDM+TKEDL TVALGTSKINY+DPRITVAWCKRHE PIEKIFNKSLL KF WAM
Sbjct: 2 KIEKMERDMQTKEDLKTVALGTSKINYMDPRITVAWCKRHEAPIEKIFNKSLLEKFAWAM 61
Query: 293 DVDPDFRF 270
DV+P F F
Sbjct: 62 DVEPHFTF 69
[30][TOP]
>UniRef100_A8IDM1 DNA topoisomerase I (Fragment) n=1 Tax=Chlamydomonas reinhardtii
RepID=A8IDM1_CHLRE
Length = 586
Score = 122 bits (305), Expect = 2e-26
Identities = 58/79 (73%), Positives = 65/79 (82%)
Frame = -2
Query: 506 ALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 327
AL KI + I K++ ++KEDL TVALGTSKINY+DPRITVAWCKR+EVPIEKIFN
Sbjct: 508 ALNSKIDKKKQAIAKVELQARSKEDLKTVALGTSKINYMDPRITVAWCKRNEVPIEKIFN 567
Query: 326 KSLLAKFTWAMDVDPDFRF 270
KSLLAKF WAMDVDP FRF
Sbjct: 568 KSLLAKFNWAMDVDPTFRF 586
[31][TOP]
>UniRef100_B5Y3I3 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B5Y3I3_PHATR
Length = 594
Score = 110 bits (275), Expect = 6e-23
Identities = 52/88 (59%), Positives = 66/88 (75%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + ++ E + KKI N KI KM+ D+K K+D V+LGTSKINY+DPRI+VAWCKR+
Sbjct: 499 KSPQTMTDEQVVKKIEAWNGKISKMEMDLKHKDDNKEVSLGTSKINYMDPRISVAWCKRN 558
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
EVPIEKIF+K+L KF WAM V PD+ F
Sbjct: 559 EVPIEKIFSKTLRDKFNWAMAVVPDWEF 586
[32][TOP]
>UniRef100_Q7RE42 Eukaryotic DNA topoisomerase I, DNA binding, putative n=1
Tax=Plasmodium yoelii yoelii RepID=Q7RE42_PLAYO
Length = 886
Score = 105 bits (263), Expect = 2e-21
Identities = 49/88 (55%), Positives = 66/88 (75%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K K+N+ E+ +KK+ K+E ++ MK ++D T+ALGTSKINY+DPRITVA+CK+
Sbjct: 799 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 858
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
E+PIEKIFN+SL KF WAM V +FRF
Sbjct: 859 EIPIEKIFNRSLRLKFPWAMFVTKNFRF 886
[33][TOP]
>UniRef100_B3L6G4 Topoisomerase I, putative n=1 Tax=Plasmodium knowlesi strain H
RepID=B3L6G4_PLAKH
Length = 924
Score = 105 bits (263), Expect = 2e-21
Identities = 49/88 (55%), Positives = 66/88 (75%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K K+N+ E+ +KK+ K+E+++ MK ++D T+ALGTSKINY+DPRITVA+CKR
Sbjct: 837 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 896
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 897 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 924
[34][TOP]
>UniRef100_A5KB33 Topoisomerase I, putative n=1 Tax=Plasmodium vivax RepID=A5KB33_PLAVI
Length = 931
Score = 105 bits (263), Expect = 2e-21
Identities = 49/88 (55%), Positives = 66/88 (75%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K K+N+ E+ +KK+ K+E+++ MK ++D T+ALGTSKINY+DPRITVA+CKR
Sbjct: 844 KVKENMKEESCKKKLIALIKKVEQLKHQMKVRDDNKTIALGTSKINYMDPRITVAFCKRF 903
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
E+PIEKIFN+SL KF WAM V +F F
Sbjct: 904 EIPIEKIFNRSLRLKFPWAMFVTKNFTF 931
[35][TOP]
>UniRef100_C1MGX0 DNA topoisomerase I n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MGX0_9CHLO
Length = 685
Score = 103 bits (257), Expect = 8e-21
Identities = 46/80 (57%), Positives = 61/80 (76%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E + KIS ++ K++ MK KEDL TV+LGTSKINYLDPRIT+AWCKR+EVP +F
Sbjct: 606 EKNKSKISTMKERLAKLELQMKMKEDLKTVSLGTSKINYLDPRITIAWCKRNEVPPPTVF 665
Query: 329 NKSLLAKFTWAMDVDPDFRF 270
++L+ KF W+M+V+PDF F
Sbjct: 666 TRALVEKFNWSMEVEPDFDF 685
[36][TOP]
>UniRef100_B8CC91 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8CC91_THAPS
Length = 536
Score = 103 bits (257), Expect = 8e-21
Identities = 47/86 (54%), Positives = 68/86 (79%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
+K + E + K+I+ + KI+KM+ ++K K+D V+LGTSK+NY+DPRI+VAWCKR+EV
Sbjct: 443 EKKPTKEQVTKRITAWSEKIKKMELNIKHKDDNKEVSLGTSKLNYMDPRISVAWCKRNEV 502
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
PIEKIF+K++ KF WAM V PD++F
Sbjct: 503 PIEKIFSKTMRDKFNWAMAVTPDWQF 528
[37][TOP]
>UniRef100_Q00XV7 Putative DNA topoisomerase I (ISS) n=1 Tax=Ostreococcus tauri
RepID=Q00XV7_OSTTA
Length = 783
Score = 103 bits (256), Expect = 1e-20
Identities = 47/86 (54%), Positives = 62/86 (72%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
KKN + +KK++ + K+ M+ KE+L TV+LGTSKINYLDPRIT++WCKRHEV
Sbjct: 674 KKNKDDKNQKKKLTALKERAAKLAIQMEMKEELKTVSLGTSKINYLDPRITLSWCKRHEV 733
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
P +F K+L+ KF WAMD D DF+F
Sbjct: 734 PPPTVFTKALIDKFHWAMDCDMDFKF 759
[38][TOP]
>UniRef100_Q9ZSC8 Topoisomerase I n=1 Tax=Nicotiana tabacum RepID=Q9ZSC8_TOBAC
Length = 852
Score = 102 bits (253), Expect = 2e-20
Identities = 46/65 (70%), Positives = 56/65 (86%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DGK K+NL+ EAL+KKI QTN KIE +++ ++TKE+L TVALGTSKINYLDPRITVAWC+
Sbjct: 788 DGKAKRNLAPEALQKKIDQTNVKIENIEKQIETKEELKTVALGTSKINYLDPRITVAWCE 847
Query: 359 RHEVP 345
RH P
Sbjct: 848 RHRFP 852
[39][TOP]
>UniRef100_Q8I3Z9 Topoisomerase I n=2 Tax=Plasmodium falciparum RepID=Q8I3Z9_PLAF7
Length = 839
Score = 101 bits (251), Expect = 4e-20
Identities = 46/88 (52%), Positives = 63/88 (71%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K K+N+ E+ +KK+ K+E + MK ++D T+ALGTSKINY+DPRITVA+CK+
Sbjct: 752 KVKENMKEESCKKKLITLIKKVELLNNQMKVRDDNKTIALGTSKINYMDPRITVAFCKKF 811
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
E+PIEK+FN+SL KF WAM +F F
Sbjct: 812 EIPIEKVFNRSLRLKFPWAMFATKNFTF 839
[40][TOP]
>UniRef100_A4S5R8 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
RepID=A4S5R8_OSTLU
Length = 491
Score = 96.3 bits (238), Expect = 1e-18
Identities = 44/86 (51%), Positives = 59/86 (68%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
KK + +KK++ + K+ M KE+L TV+LGTSKINYLDPRIT++WCKRHEV
Sbjct: 394 KKKTDDKNQKKKLAALKERQSKLAIQMNMKEELKTVSLGTSKINYLDPRITLSWCKRHEV 453
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
P +F K+L+ KF WAMD + +F F
Sbjct: 454 PPNVVFTKALIDKFHWAMDCEMEFSF 479
[41][TOP]
>UniRef100_Q5CY81 Eukaryotic DNA topoisomerase I (Fragment) n=1 Tax=Cryptosporidium
parvum Iowa II RepID=Q5CY81_CRYPV
Length = 653
Score = 95.9 bits (237), Expect = 2e-18
Identities = 47/95 (49%), Positives = 66/95 (69%), Gaps = 5/95 (5%)
Frame = -2
Query: 539 DGKKKK-----NLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRIT 375
+GK++K N S + ++KKI +KI + +K K+D TVAL TSKINY+DPRI+
Sbjct: 559 NGKQRKYPINLNSSLDVVQKKIDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRIS 618
Query: 374 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
VA+CK++++PI+KIFN+SL KF WAM DF F
Sbjct: 619 VAFCKKYDLPIDKIFNRSLRTKFPWAMYTRSDFSF 653
[42][TOP]
>UniRef100_Q5CN58 DNA topoisomerase I n=1 Tax=Cryptosporidium hominis
RepID=Q5CN58_CRYHO
Length = 641
Score = 95.9 bits (237), Expect = 2e-18
Identities = 47/95 (49%), Positives = 66/95 (69%), Gaps = 5/95 (5%)
Frame = -2
Query: 539 DGKKKK-----NLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRIT 375
+GK++K N S + ++KKI +KI + +K K+D TVAL TSKINY+DPRI+
Sbjct: 547 NGKQRKYPINLNSSLDVVQKKIDSIKSKISNLYLKIKIKDDNKTVALNTSKINYMDPRIS 606
Query: 374 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
VA+CK++++PI+KIFN+SL KF WAM DF F
Sbjct: 607 VAFCKKYDLPIDKIFNRSLRTKFPWAMYTRSDFSF 641
[43][TOP]
>UniRef100_Q4N5U3 DNA topoisomerase I, putative n=1 Tax=Theileria parva
RepID=Q4N5U3_THEPA
Length = 1003
Score = 95.9 bits (237), Expect = 2e-18
Identities = 51/94 (54%), Positives = 64/94 (68%), Gaps = 8/94 (8%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTN----AKIEKMQRD----MKTKEDLNTVALGTSKINYLDPRITV 372
K + EA + K+S N A ++K Q+D M K+ TVALGTSKINY+DPRITV
Sbjct: 910 KPGMKLEAAKNKLSTLNYLCFAPLKKKQKDHAIKMTIKDSNKTVALGTSKINYMDPRITV 969
Query: 371 AWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
A+CK++E+PIEK+FNKSL KF WAM V DF F
Sbjct: 970 AFCKKYEIPIEKVFNKSLRMKFPWAMYVRSDFTF 1003
[44][TOP]
>UniRef100_A7AUT4 DNA topoisomerase n=1 Tax=Babesia bovis RepID=A7AUT4_BABBO
Length = 701
Score = 95.5 bits (236), Expect = 2e-18
Identities = 47/86 (54%), Positives = 60/86 (69%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
++ + EA +KK+ + + M+ K+D TVALGTSKINY+DPRITVA+CKR+EV
Sbjct: 616 RQGMKLEACQKKLETAMKRSKVHAIKMRIKDDNKTVALGTSKINYMDPRITVAFCKRYEV 675
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
PIEKIFNKSL KF WAM D+ F
Sbjct: 676 PIEKIFNKSLRTKFPWAMYAGADYIF 701
[45][TOP]
>UniRef100_B6ABX7 DNA topoisomerase I, putative n=1 Tax=Cryptosporidium muris RN66
RepID=B6ABX7_9CRYT
Length = 660
Score = 94.7 bits (234), Expect = 4e-18
Identities = 46/95 (48%), Positives = 67/95 (70%), Gaps = 5/95 (5%)
Frame = -2
Query: 539 DGKKKK---NLSS--EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRIT 375
+GK +K NLSS E ++KK+ K+ ++ +K K+D TV+L TSK+NY+DPRI+
Sbjct: 566 NGKPRKFPINLSSNSEIIQKKLDSIKTKLSNLELKIKIKDDNKTVSLNTSKLNYMDPRIS 625
Query: 374 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
VA+CK++E+PI+K+FN+SL KF WAM DF F
Sbjct: 626 VAFCKKYELPIDKVFNRSLRTKFPWAMYTRSDFSF 660
[46][TOP]
>UniRef100_C1FD86 DNA topoisomerase I n=1 Tax=Micromonas sp. RCC299
RepID=C1FD86_9CHLO
Length = 635
Score = 94.4 bits (233), Expect = 5e-18
Identities = 39/75 (52%), Positives = 57/75 (76%)
Frame = -2
Query: 494 KISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 315
KI ++ K++ MK K++L +V+LGTSKINY+DPRIT+AWCK ++VP ++ K+L+
Sbjct: 561 KIRTLKERLSKLELQMKMKDELKSVSLGTSKINYMDPRITIAWCKHNDVPPPTVYTKALV 620
Query: 314 AKFTWAMDVDPDFRF 270
KF WAM+V+PDF F
Sbjct: 621 EKFNWAMEVEPDFDF 635
[47][TOP]
>UniRef100_Q4UDP8 DNA topoisomerase i, putative n=1 Tax=Theileria annulata
RepID=Q4UDP8_THEAN
Length = 999
Score = 93.2 bits (230), Expect = 1e-17
Identities = 46/86 (53%), Positives = 58/86 (67%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K + EA + K++ K + M K+ TVALGTSKINY+DPRITVA+CK++E+
Sbjct: 914 KPGMKLEAAKNKLATLKKKQKDHNIKMTIKDSNKTVALGTSKINYMDPRITVAFCKKYEI 973
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
PIEK+FNKSL KF WAM V DF F
Sbjct: 974 PIEKVFNKSLRMKFPWAMCVRSDFTF 999
[48][TOP]
>UniRef100_UPI000056C59B UPI000056C59B related cluster n=1 Tax=Danio rerio
RepID=UPI000056C59B
Length = 196
Score = 92.0 bits (227), Expect = 2e-17
Identities = 45/86 (52%), Positives = 63/86 (73%), Gaps = 4/86 (4%)
Frame = -2
Query: 515 SSEALEKK---ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
SS+ +EKK + + +++K+Q +E+ +ALGTSK+NYLDPRITVAWCK+H+VP
Sbjct: 111 SSKLVEKKQKAVQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVP 170
Query: 344 IEKIFNKSLLAKFTWAMDV-DPDFRF 270
IEKIFNK+ KF WA+D+ D F+F
Sbjct: 171 IEKIFNKTHREKFAWAIDMTDESFQF 196
[49][TOP]
>UniRef100_Q6T721 Mitochondrial topoisomerase I n=1 Tax=Danio rerio
RepID=Q6T721_DANRE
Length = 600
Score = 92.0 bits (227), Expect = 2e-17
Identities = 45/86 (52%), Positives = 63/86 (73%), Gaps = 4/86 (4%)
Frame = -2
Query: 515 SSEALEKK---ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
SS+ +EKK + + +++K+Q +E+ +ALGTSK+NYLDPRITVAWCK+H+VP
Sbjct: 515 SSKLVEKKQKAVQRLCDQLKKLQLQETDREENKVIALGTSKLNYLDPRITVAWCKKHQVP 574
Query: 344 IEKIFNKSLLAKFTWAMDV-DPDFRF 270
IEKIFNK+ KF WA+D+ D F+F
Sbjct: 575 IEKIFNKTHREKFAWAIDMTDESFQF 600
[50][TOP]
>UniRef100_A8N6Y9 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N6Y9_COPC7
Length = 863
Score = 92.0 bits (227), Expect = 2e-17
Identities = 44/86 (51%), Positives = 62/86 (72%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K+ +E LE+ I + + +I+ + M +++ VALGTSKINYLDPRITVAW ++V
Sbjct: 778 KRERPTEKLEEMIEKLDDRIKTFKLQMIDRDEGKEVALGTSKINYLDPRITVAWASANKV 837
Query: 347 PIEKIFNKSLLAKFTWAMDVDPDFRF 270
PIEK+F+K+LL KF WAM VD D++F
Sbjct: 838 PIEKMFSKTLLEKFPWAMGVDDDWKF 863
[51][TOP]
>UniRef100_Q24BB2 Eukaryotic DNA topoisomerase I, catalytic core family protein n=1
Tax=Tetrahymena thermophila SB210 RepID=Q24BB2_TETTH
Length = 713
Score = 91.7 bits (226), Expect = 3e-17
Identities = 44/95 (46%), Positives = 63/95 (66%), Gaps = 5/95 (5%)
Frame = -2
Query: 539 DGKKKKNL-----SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRIT 375
DGK K + + E +++ I + KI++ Q ++KE +ALGTSK NY DPRI+
Sbjct: 619 DGKHKMFVKKFPGTKEKIQEAIEKIKKKIDEEQNKKQSKEKNKEIALGTSKTNYNDPRIS 678
Query: 374 VAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
V WCK+ EVP+EK+F K+L+AKF WAMD D ++ F
Sbjct: 679 VVWCKKWEVPVEKVFPKTLIAKFVWAMDTDLEWSF 713
[52][TOP]
>UniRef100_B4L533 GI21653 n=1 Tax=Drosophila mojavensis RepID=B4L533_DROMO
Length = 1043
Score = 90.1 bits (222), Expect = 9e-17
Identities = 41/90 (45%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ L+++ K++ + +++K++ +++ T+ALGTSK+NYLDPRITVAWCK+
Sbjct: 954 GSVKEKLNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKK 1013
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1014 YGVPIEKIFNKTHRTKFLWAIHMADENYRF 1043
[53][TOP]
>UniRef100_UPI00015B4D8F PREDICTED: similar to DNA topoisomerase type I n=1 Tax=Nasonia
vitripennis RepID=UPI00015B4D8F
Length = 1019
Score = 89.7 bits (221), Expect = 1e-16
Identities = 41/90 (45%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + E +K++ + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 930 GSVKEKVLYEKKKKQLDRLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKK 989
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
H+VPIEKI+NK+ KF WA+D+ PD+ F
Sbjct: 990 HDVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1019
[54][TOP]
>UniRef100_P07799 DNA topoisomerase 1 n=1 Tax=Schizosaccharomyces pombe
RepID=TOP1_SCHPO
Length = 814
Score = 89.7 bits (221), Expect = 1e-16
Identities = 40/82 (48%), Positives = 60/82 (73%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E LEK++++ N +I M+ M K++ T ALGTSKINY+DPR+T ++ KR +VPIEK
Sbjct: 733 SMEQLEKRLNKLNERINVMRTQMIDKDENKTTALGTSKINYIDPRLTYSFSKREDVPIEK 792
Query: 335 IFNKSLLAKFTWAMDVDPDFRF 270
+F+K++ KF WA D PD+++
Sbjct: 793 LFSKTIRDKFNWAADTPPDWKW 814
[55][TOP]
>UniRef100_UPI0001555600 PREDICTED: similar to mitochondrial topoisomerase I n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555600
Length = 689
Score = 89.4 bits (220), Expect = 2e-16
Identities = 47/95 (49%), Positives = 65/95 (68%), Gaps = 5/95 (5%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKK---ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITV 372
D K KK++ S++ LEKK + + ++ K+ KE+ +ALGTSK+NYLDPRI+V
Sbjct: 595 DHKAKKDIKSKSNLEKKKKLLQKIEEQLMKLSVQATDKEENKQIALGTSKLNYLDPRISV 654
Query: 371 AWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
AWCK+ VPIEKI+NK+ KF WA+D+ D DF F
Sbjct: 655 AWCKKFGVPIEKIYNKTQREKFAWAIDMADEDFEF 689
[56][TOP]
>UniRef100_Q54RC3 DNA topoisomerase 1 n=1 Tax=Dictyostelium discoideum RepID=TOP1_DICDI
Length = 893
Score = 89.0 bits (219), Expect = 2e-16
Identities = 43/78 (55%), Positives = 60/78 (76%)
Frame = -2
Query: 503 LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 324
+++KI++ +I+K + K++L TVALGTSKINYLDPRITVAWCK+++VP++KIF K
Sbjct: 817 IKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPVDKIFTK 876
Query: 323 SLLAKFTWAMDVDPDFRF 270
SL KF W+ DV D+ F
Sbjct: 877 SLRDKFPWS-DVGTDYIF 893
[57][TOP]
>UniRef100_UPI0000DB758E PREDICTED: similar to DNA topoisomerase I n=1 Tax=Apis mellifera
RepID=UPI0000DB758E
Length = 973
Score = 88.6 bits (218), Expect = 3e-16
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E +K + + ++ K++ KE+ +ALGTSK+NYLDPRITVAWCK+H VPIEKI+
Sbjct: 893 EKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIY 952
Query: 329 NKSLLAKFTWAMDV-DPDFRF 270
NK+ KF WA+D+ PD+ F
Sbjct: 953 NKTQRDKFRWAIDMAGPDYVF 973
[58][TOP]
>UniRef100_UPI000186E5D8 DNA topoisomerase, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E5D8
Length = 961
Score = 87.8 bits (216), Expect = 4e-16
Identities = 43/92 (46%), Positives = 65/92 (70%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKK-ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
+ K+ + +EA +KK + + ++ K++ KE+ T+ALGTSK+NYLDPRI+VAWC
Sbjct: 870 NAKRNGDSGTEAKKKKQLDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWC 929
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
K++ VPIEKI+NK+ KF WA+D+ PD+ F
Sbjct: 930 KKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 961
[59][TOP]
>UniRef100_Q8IR39 Topoisomerase 1, isoform B n=1 Tax=Drosophila melanogaster
RepID=Q8IR39_DROME
Length = 581
Score = 87.8 bits (216), Expect = 4e-16
Identities = 38/77 (49%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 505 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 564
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 565 RTKFLWAVHMADENYRF 581
[60][TOP]
>UniRef100_Q494M1 Topoisomerase 1, isoform C n=1 Tax=Drosophila melanogaster
RepID=Q494M1_DROME
Length = 974
Score = 87.8 bits (216), Expect = 4e-16
Identities = 38/77 (49%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 898 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 957
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 958 RTKFLWAVHMADENYRF 974
[61][TOP]
>UniRef100_C6TPA7 AT12251p n=1 Tax=Drosophila melanogaster RepID=C6TPA7_DROME
Length = 581
Score = 87.8 bits (216), Expect = 4e-16
Identities = 38/77 (49%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 505 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 564
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 565 RTKFLWAVHMADENYRF 581
[62][TOP]
>UniRef100_B3NTM5 GG17874 n=1 Tax=Drosophila erecta RepID=B3NTM5_DROER
Length = 969
Score = 87.8 bits (216), Expect = 4e-16
Identities = 38/77 (49%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 893 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 952
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 953 RTKFLWAVHMADENYRF 969
[63][TOP]
>UniRef100_P30189 DNA topoisomerase 1 n=1 Tax=Drosophila melanogaster RepID=TOP1_DROME
Length = 972
Score = 87.8 bits (216), Expect = 4e-16
Identities = 38/77 (49%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+
Sbjct: 896 KQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQ 955
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 956 RTKFLWAVHMADENYRF 972
[64][TOP]
>UniRef100_UPI00017EFDA4 PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Sus
scrofa RepID=UPI00017EFDA4
Length = 748
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 660 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 717
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 718 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 748
[65][TOP]
>UniRef100_UPI0001797824 PREDICTED: similar to topoisomerase I, partial n=1 Tax=Equus
caballus RepID=UPI0001797824
Length = 765
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[66][TOP]
>UniRef100_UPI00006D45A8 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Macaca mulatta
RepID=UPI00006D45A8
Length = 767
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
[67][TOP]
>UniRef100_UPI00005A45B7 PREDICTED: similar to DNA topoisomerase I n=1 Tax=Canis lupus
familiaris RepID=UPI00005A45B7
Length = 1004
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 916 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 973
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 974 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 1004
[68][TOP]
>UniRef100_UPI0001B7BF13 similar to topoisomerase (DNA) I (LOC499179), mRNA n=1 Tax=Rattus
norvegicus RepID=UPI0001B7BF13
Length = 760
Score = 87.4 bits (215), Expect = 6e-16
Identities = 44/91 (48%), Positives = 61/91 (67%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK +S + +++ + K+E D +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 673 DAKTKKVVSKKKAVQRLEEQLMKLEVQATD---REENKQIALGTSKLNYLDPRITVAWCK 729
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 730 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 760
[69][TOP]
>UniRef100_UPI00015DF5D0 topoisomerase (DNA) I n=1 Tax=Mus musculus RepID=UPI00015DF5D0
Length = 758
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 670 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 727
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 728 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 758
[70][TOP]
>UniRef100_UPI0000EB0F30 Topoisomerase I n=1 Tax=Canis lupus familiaris RepID=UPI0000EB0F30
Length = 752
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 664 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 721
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 722 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 752
[71][TOP]
>UniRef100_UPI00006154BF PREDICTED: topoisomerase (DNA) I n=1 Tax=Bos taurus
RepID=UPI00006154BF
Length = 769
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 681 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 738
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 739 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 769
[72][TOP]
>UniRef100_Q6LBJ1 Topoisomerase I (Fragment) n=1 Tax=Mus musculus RepID=Q6LBJ1_MOUSE
Length = 115
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 27 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 84
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 85 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 115
[73][TOP]
>UniRef100_Q3TSR2 Putative uncharacterized protein (Fragment) n=1 Tax=Mus musculus
RepID=Q3TSR2_MOUSE
Length = 144
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 56 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 113
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 114 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 144
[74][TOP]
>UniRef100_Q5IFJ5 TOP1 (Fragment) n=1 Tax=Macaca fascicularis RepID=Q5IFJ5_MACFA
Length = 560
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 472 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 529
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 530 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 560
[75][TOP]
>UniRef100_B9Q6S5 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii VEG
RepID=B9Q6S5_TOXGO
Length = 953
Score = 87.4 bits (215), Expect = 6e-16
Identities = 41/60 (68%), Positives = 48/60 (80%)
Frame = -2
Query: 449 MKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
+K K+D TVALGTSKINY+DPRITVA+CK++EVPIEK+FNKSL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[76][TOP]
>UniRef100_B9PWF4 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii GT1
RepID=B9PWF4_TOXGO
Length = 953
Score = 87.4 bits (215), Expect = 6e-16
Identities = 41/60 (68%), Positives = 48/60 (80%)
Frame = -2
Query: 449 MKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
+K K+D TVALGTSKINY+DPRITVA+CK++EVPIEK+FNKSL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[77][TOP]
>UniRef100_B6KM03 DNA topoisomerase I, putative n=1 Tax=Toxoplasma gondii ME49
RepID=B6KM03_TOXGO
Length = 953
Score = 87.4 bits (215), Expect = 6e-16
Identities = 41/60 (68%), Positives = 48/60 (80%)
Frame = -2
Query: 449 MKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
+K K+D TVALGTSKINY+DPRITVA+CK++EVPIEK+FNKSL KF WAM F F
Sbjct: 894 IKLKDDNKTVALGTSKINYMDPRITVAFCKKYEVPIEKLFNKSLRLKFPWAMFAKSTFEF 953
[78][TOP]
>UniRef100_B5DMS2 GA24044 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=B5DMS2_DROPS
Length = 1054
Score = 87.4 bits (215), Expect = 6e-16
Identities = 39/90 (43%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ ++++ K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 965 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1024
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1025 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1054
[79][TOP]
>UniRef100_B4GVZ4 GL14571 n=1 Tax=Drosophila persimilis RepID=B4GVZ4_DROPE
Length = 1042
Score = 87.4 bits (215), Expect = 6e-16
Identities = 39/90 (43%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ ++++ K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 953 GSVKEKVNADKKGKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 1012
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1013 NGVPIEKIFNKTQRTKFLWAVHMADENYRF 1042
[80][TOP]
>UniRef100_Q9BVT2 Putative uncharacterized protein (Fragment) n=1 Tax=Homo sapiens
RepID=Q9BVT2_HUMAN
Length = 176
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 88 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 145
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 146 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 176
[81][TOP]
>UniRef100_B9EG90 Topoisomerase (DNA) I n=1 Tax=Homo sapiens RepID=B9EG90_HUMAN
Length = 765
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[82][TOP]
>UniRef100_Q9WUL0 DNA topoisomerase 1 n=1 Tax=Rattus norvegicus RepID=TOP1_RAT
Length = 767
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[83][TOP]
>UniRef100_Q04750 DNA topoisomerase 1 n=1 Tax=Mus musculus RepID=TOP1_MOUSE
Length = 767
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[84][TOP]
>UniRef100_P11387 DNA topoisomerase 1 n=1 Tax=Homo sapiens RepID=TOP1_HUMAN
Length = 765
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 677 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 735 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
[85][TOP]
>UniRef100_Q07050 DNA topoisomerase 1 n=1 Tax=Cricetulus griseus RepID=TOP1_CRIGR
Length = 767
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
[86][TOP]
>UniRef100_Q7YR26 DNA topoisomerase 1 n=1 Tax=Chlorocebus aethiops RepID=TOP1_CERAE
Length = 767
Score = 87.4 bits (215), Expect = 6e-16
Identities = 43/91 (47%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRITVAWCK
Sbjct: 679 DAKTKKVVESK--KKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 737 KWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
[87][TOP]
>UniRef100_Q6T722 Mitochondrial topoisomerase I n=1 Tax=Gallus gallus
RepID=Q6T722_CHICK
Length = 593
Score = 87.0 bits (214), Expect = 8e-16
Identities = 44/93 (47%), Positives = 61/93 (65%), Gaps = 5/93 (5%)
Frame = -2
Query: 533 KKKKNLSSEA----LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAW 366
K KK+ +EA +K + + ++ K+ KE+ +ALGTSK+NYLDPRI++AW
Sbjct: 501 KDKKDAKAEANVQKKKKLLERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAW 560
Query: 365 CKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
CK+ VPIEKIFNK+ KF WA+D+ D DF F
Sbjct: 561 CKKFGVPIEKIFNKTQREKFAWAIDMTDEDFEF 593
[88][TOP]
>UniRef100_C5DEP3 KLTH0C10890p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DEP3_LACTC
Length = 756
Score = 87.0 bits (214), Expect = 8e-16
Identities = 43/88 (48%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
K + S+E L+ +I + + +IE +K KED + VALGTSKINY+DPR++V +CK++
Sbjct: 669 KTNSESAEKLKMQIEKLDQRIETATIQLKDKEDNSQVALGTSKINYIDPRLSVVFCKKYG 728
Query: 350 VPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
VPIEK+F KSL KF WA++ D ++RF
Sbjct: 729 VPIEKVFTKSLRDKFKWAIESADENWRF 756
[89][TOP]
>UniRef100_B4ILF9 GM19769 n=1 Tax=Drosophila sechellia RepID=B4ILF9_DROSE
Length = 970
Score = 86.7 bits (213), Expect = 1e-15
Identities = 48/103 (46%), Positives = 67/103 (65%), Gaps = 15/103 (14%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDM-------------KTKEDLN-TVALGTSKIN 396
K+K EA+EK S+ N++ EK + + +T D N T+ALGTSK+N
Sbjct: 868 KEKIKAKREAIEKCESEYNSRDEKKGKQLDRLRDQLKKLELQETDRDENKTIALGTSKLN 927
Query: 395 YLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
YLDPRI+VAWCK+++VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 928 YLDPRISVAWCKKNDVPIEKIFNKTQRTKFLWAVHMADENYRF 970
[90][TOP]
>UniRef100_B3MR83 GF21232 n=1 Tax=Drosophila ananassae RepID=B3MR83_DROAN
Length = 990
Score = 86.7 bits (213), Expect = 1e-15
Identities = 38/77 (49%), Positives = 58/77 (75%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+H VPIEKIFNK+
Sbjct: 914 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIFNKTQ 973
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 974 RTKFLWAVHMADENYRF 990
[91][TOP]
>UniRef100_B0WA62 Putative uncharacterized protein n=1 Tax=Culex quinquefasciatus
RepID=B0WA62_CULQU
Length = 962
Score = 86.7 bits (213), Expect = 1e-15
Identities = 37/83 (44%), Positives = 60/83 (72%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K ++ + +K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 873 GSVKGSVDRDKKQKQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKK 932
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV 288
+VPIEKIFNK+ KF WA+D+
Sbjct: 933 FDVPIEKIFNKTQRDKFRWAIDM 955
[92][TOP]
>UniRef100_B4M707 GJ16891 n=1 Tax=Drosophila virilis RepID=B4M707_DROVI
Length = 1045
Score = 86.3 bits (212), Expect = 1e-15
Identities = 40/90 (44%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + ++ K + + +++K++ +++ T+ALGTSK+NYLDPRITVAWCK+
Sbjct: 956 GSVKERVIADKKGKILERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRITVAWCKK 1015
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1016 YGVPIEKIFNKTHRTKFLWAIHMADENYRF 1045
[93][TOP]
>UniRef100_A7SLG4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SLG4_NEMVE
Length = 502
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/95 (45%), Positives = 61/95 (64%), Gaps = 8/95 (8%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDM-------KTKEDLNTVALGTSKINYLDPRITV 372
K K SE+ K + + A++++++ + KE+ +ALGTSK+NYLDPRITV
Sbjct: 408 KAKESKSESNNKAVEKKKAQVQRLEEQLFKLEVTATDKEENKEIALGTSKLNYLDPRITV 467
Query: 371 AWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
AWCK+ EVPIEK +NK+ KF WA+D+ DF F
Sbjct: 468 AWCKKFEVPIEKAYNKTQREKFAWAIDMAGEDFVF 502
[94][TOP]
>UniRef100_C5DTC9 ZYRO0C07458p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DTC9_ZYGRC
Length = 843
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/88 (47%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
K + S E LEK+I + + +IE ++ KE+ + V+LGTSKINY+DPR++V +CK++
Sbjct: 756 KSSSNSIEKLEKQIEKLDQRIETSSIQLRDKEENSQVSLGTSKINYIDPRLSVVFCKKYG 815
Query: 350 VPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
VPIE+IF KSL KF WA++ D ++RF
Sbjct: 816 VPIERIFTKSLREKFKWAIESADENWRF 843
[95][TOP]
>UniRef100_A7TJW1 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJW1_VANPO
Length = 799
Score = 86.3 bits (212), Expect = 1e-15
Identities = 41/81 (50%), Positives = 59/81 (72%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E LEK I + +I+ +K KE+ + V+LGTSKINY+DPR++V +CK+ ++PIEKIF
Sbjct: 719 EKLEKNIEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKFDIPIEKIF 778
Query: 329 NKSLLAKFTWAMD-VDPDFRF 270
KSL KF WA++ VD ++RF
Sbjct: 779 TKSLREKFRWAIESVDENWRF 799
[96][TOP]
>UniRef100_UPI00017B1DB6 UPI00017B1DB6 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B1DB6
Length = 770
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 682 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 739
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 740 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 770
[97][TOP]
>UniRef100_UPI00016E5FAF UPI00016E5FAF related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5FAF
Length = 573
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 485 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 542
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 543 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 573
[98][TOP]
>UniRef100_UPI00016E5F98 UPI00016E5F98 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F98
Length = 790
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 702 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 759
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 760 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 790
[99][TOP]
>UniRef100_UPI00016E5F96 UPI00016E5F96 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F96
Length = 767
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 679 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 737 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 767
[100][TOP]
>UniRef100_Q90WS0 Topoisomerase I alpha n=1 Tax=Takifugu rubripes RepID=Q90WS0_TAKRU
Length = 767
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 679 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 736
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 737 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 767
[101][TOP]
>UniRef100_Q4T6N6 Chromosome 9 SCAF8684, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4T6N6_TETNG
Length = 783
Score = 85.9 bits (211), Expect = 2e-15
Identities = 42/91 (46%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 695 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 752
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + DF F
Sbjct: 753 KFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 783
[102][TOP]
>UniRef100_C7E3P0 Topoisomerase family protein (Fragment) n=1 Tax=Caenorhabditis
brenneri RepID=C7E3P0_CAEBE
Length = 159
Score = 85.9 bits (211), Expect = 2e-15
Identities = 37/82 (45%), Positives = 55/82 (67%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + E +KK + +++K++ K++ +ALGTSK+NYLDPRITVAWCK H
Sbjct: 68 KHARGADKEKAQKKYDRLKEQLKKLKIARTDKDENKQIALGTSKLNYLDPRITVAWCKEH 127
Query: 353 EVPIEKIFNKSLLAKFTWAMDV 288
+VP+EK+F K+ KF WA+D+
Sbjct: 128 DVPLEKVFTKTHREKFRWAIDM 149
[103][TOP]
>UniRef100_UPI000194BDF0 PREDICTED: topoisomerase (DNA) I, mitochondrial n=1 Tax=Taeniopygia
guttata RepID=UPI000194BDF0
Length = 662
Score = 85.5 bits (210), Expect = 2e-15
Identities = 41/87 (47%), Positives = 57/87 (65%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K L+ E +K + + ++ KM KE+ +ALGTSK+NYLDPRITVAWCK+ +
Sbjct: 576 KAELNVEKKKKLLKRLEEQLAKMNIQATDKEENKQIALGTSKLNYLDPRITVAWCKKFGI 635
Query: 347 PIEKIFNKSLLAKFTWAMDV-DPDFRF 270
PIE+I+NK+ KF WA+D+ DF F
Sbjct: 636 PIERIYNKTQREKFAWAIDMAGEDFEF 662
[104][TOP]
>UniRef100_UPI0001792028 PREDICTED: similar to AGAP004078-PA n=1 Tax=Acyrthosiphon pisum
RepID=UPI0001792028
Length = 1011
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/84 (46%), Positives = 55/84 (65%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
DG E +K + + ++ K++ KE+ T+ALGTSK+NYLDPRI+VAWCK
Sbjct: 657 DGSVHSKTQLEKRKKALERLKEQLTKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCK 716
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV 288
+ VPIEKI+NK+ KF WA+D+
Sbjct: 717 KFNVPIEKIYNKTQRDKFRWAIDM 740
[105][TOP]
>UniRef100_B4NCJ2 GK25865 n=1 Tax=Drosophila willistoni RepID=B4NCJ2_DROWI
Length = 997
Score = 85.5 bits (210), Expect = 2e-15
Identities = 38/90 (42%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ ++++ K++ + +++K++ +++ T+AL TSK+NYLDPRI+VAWCK+
Sbjct: 908 GSVKEKVNADKKGKQLERLKEQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKK 967
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 968 NGVPIEKIFNKTQRTKFLWAIHMADENYRF 997
[106][TOP]
>UniRef100_B4JLU3 GH24453 n=1 Tax=Drosophila grimshawi RepID=B4JLU3_DROGR
Length = 1063
Score = 85.5 bits (210), Expect = 2e-15
Identities = 38/90 (42%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ ++++ K++ + +++K++ +++ T+AL TSK+NYLDPRI+VAWCK+
Sbjct: 974 GSVKEKVNADKKAKQLERLKDQLKKLELQETDRDENKTIALSTSKLNYLDPRISVAWCKK 1033
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+ + D ++RF
Sbjct: 1034 NGVPIEKIFNKTQRTKFLWAIHMADENYRF 1063
[107][TOP]
>UniRef100_A8XXL4 C. briggsae CBR-TOP-1 protein n=1 Tax=Caenorhabditis briggsae AF16
RepID=A8XXL4_CAEBR
Length = 840
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/92 (42%), Positives = 59/92 (64%), Gaps = 4/92 (4%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + E +KK Q +++K++ K++ +ALGTSK+NY+DPRITVAWCK+
Sbjct: 749 KSARGAEKEKAQKKYDQKKEQLKKLKIQRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 808
Query: 353 EVPIEKIFNKSLLAKFTWAMDV----DPDFRF 270
EVP+E++F K+ KF WA+D+ D +F F
Sbjct: 809 EVPLERVFTKTHREKFRWAIDMTMTTDEEFVF 840
[108][TOP]
>UniRef100_UPI000155C8C4 PREDICTED: similar to topoisomerase I n=1 Tax=Ornithorhynchus
anatinus RepID=UPI000155C8C4
Length = 781
Score = 85.1 bits (209), Expect = 3e-15
Identities = 41/91 (45%), Positives = 61/91 (67%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 693 DAKSKKVV--ETKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 750
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 751 KWGIPIEKIYNKTQREKFAWAIDMADEDYEF 781
[109][TOP]
>UniRef100_UPI0000ECD01B topoisomerase (DNA) I, mitochondrial n=1 Tax=Gallus gallus
RepID=UPI0000ECD01B
Length = 593
Score = 85.1 bits (209), Expect = 3e-15
Identities = 42/91 (46%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K N+ + +K + + ++ K+ KE+ +ALGTSK+NYLDPRI++AWCK
Sbjct: 505 DAKAAGNVQKK--KKLLERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCK 562
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKIFNK+ KF WA+D+ D DF F
Sbjct: 563 KFGVPIEKIFNKTQREKFAWAIDMTDEDFEF 593
[110][TOP]
>UniRef100_B4PWL3 GE17178 n=1 Tax=Drosophila yakuba RepID=B4PWL3_DROYA
Length = 580
Score = 85.1 bits (209), Expect = 3e-15
Identities = 37/77 (48%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+++VPIEKIFNK+
Sbjct: 504 KQLERLKDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKNDVPIEKIFNKTQ 563
Query: 317 LAKFTWAMDV-DPDFRF 270
KF WA+ + D ++RF
Sbjct: 564 RTKFLWAVHMADENYRF 580
[111][TOP]
>UniRef100_Q6FNH4 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FNH4_CANGA
Length = 744
Score = 85.1 bits (209), Expect = 3e-15
Identities = 40/83 (48%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E LEK++ + +I+ +K KE+ + V+LGTSKINY+DPR++V +CK++ VPIEK
Sbjct: 662 SVEKLEKQVEKLEERIKTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYNVPIEK 721
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
IF K+L KF WA++ D ++RF
Sbjct: 722 IFTKTLREKFAWAIESADENWRF 744
[112][TOP]
>UniRef100_Q0UUB0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UUB0_PHANO
Length = 887
Score = 85.1 bits (209), Expect = 3e-15
Identities = 44/86 (51%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE I + N +IE M+ M+ KE VALGTSKINY+DPR+TV + K+ +VP
Sbjct: 802 KGPTVEKLEANIDKINQRIENMRIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFDVP 861
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD D+ F
Sbjct: 862 IEKFFSKTLREKFDWAIKSVDEDWEF 887
[113][TOP]
>UniRef100_UPI000194D872 PREDICTED: topoisomerase (DNA) I n=1 Tax=Taeniopygia guttata
RepID=UPI000194D872
Length = 775
Score = 84.7 bits (208), Expect = 4e-15
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 687 DEKSKKTVESK--KKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 744
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 745 KWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 775
[114][TOP]
>UniRef100_A0DKX8 Chromosome undetermined scaffold_55, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DKX8_PARTE
Length = 596
Score = 84.7 bits (208), Expect = 4e-15
Identities = 41/98 (41%), Positives = 64/98 (65%), Gaps = 8/98 (8%)
Frame = -2
Query: 539 DGKKKKNL--------SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDP 384
+G +KKN + +++ I +T K +K + ++ KE+ +ALGTSK NY DP
Sbjct: 499 EGSQKKNSIFIKKFPGQHDKIKQTIQKTQEKYQKELKGLEKKEENKEIALGTSKTNYNDP 558
Query: 383 RITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
RI+VA+CK H+VPIE++F+K+L KF WAM D +++F
Sbjct: 559 RISVAFCKVHDVPIERVFSKTLRNKFIWAMATDSNWKF 596
[115][TOP]
>UniRef100_O17966-2 Isoform b of DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans
RepID=O17966-2
Length = 734
Score = 84.7 bits (208), Expect = 4e-15
Identities = 36/82 (43%), Positives = 55/82 (67%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + E +KK + +++K++ K++ +ALGTSK+NY+DPRITVAWCK+
Sbjct: 643 KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 702
Query: 353 EVPIEKIFNKSLLAKFTWAMDV 288
EVP+EK+F K+ KF WA+D+
Sbjct: 703 EVPLEKVFTKTHREKFRWAIDM 724
[116][TOP]
>UniRef100_O17966 DNA topoisomerase 1 n=1 Tax=Caenorhabditis elegans RepID=TOP1_CAEEL
Length = 806
Score = 84.7 bits (208), Expect = 4e-15
Identities = 36/82 (43%), Positives = 55/82 (67%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + E +KK + +++K++ K++ +ALGTSK+NY+DPRITVAWCK+
Sbjct: 715 KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKF 774
Query: 353 EVPIEKIFNKSLLAKFTWAMDV 288
EVP+EK+F K+ KF WA+D+
Sbjct: 775 EVPLEKVFTKTHREKFRWAIDM 796
[117][TOP]
>UniRef100_UPI00017582B6 PREDICTED: similar to conserved hypothetical protein n=1
Tax=Tribolium castaneum RepID=UPI00017582B6
Length = 936
Score = 84.3 bits (207), Expect = 5e-15
Identities = 39/90 (43%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + +K + + ++ K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 847 GSVKEKTVYDKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKK 906
Query: 356 HEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI+NK+ KF WA+D+ PD+ F
Sbjct: 907 YGVPIEKIYNKTQRDKFRWAIDMAGPDYVF 936
[118][TOP]
>UniRef100_UPI00016E5C65 UPI00016E5C65 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5C65
Length = 755
Score = 84.3 bits (207), Expect = 5e-15
Identities = 40/91 (43%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + EA +K + + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 667 DEKSKKAV--EAKKKAVQRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 724
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +P+EKI+NK+ KF WA+D+ + D+ F
Sbjct: 725 KWGIPVEKIYNKTQREKFAWAIDMAEDDYEF 755
[119][TOP]
>UniRef100_Q90WS1 Topoisomerase I beta n=1 Tax=Takifugu rubripes RepID=Q90WS1_TAKRU
Length = 753
Score = 84.3 bits (207), Expect = 5e-15
Identities = 40/91 (43%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + EA +K + + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 665 DEKSKKAV--EAKKKAVQRIDDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 722
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +P+EKI+NK+ KF WA+D+ + D+ F
Sbjct: 723 KWGIPVEKIYNKTQREKFAWAIDMAEDDYEF 753
[120][TOP]
>UniRef100_Q17HT9 DNA topoisomerase type I n=1 Tax=Aedes aegypti RepID=Q17HT9_AEDAE
Length = 966
Score = 84.3 bits (207), Expect = 5e-15
Identities = 36/80 (45%), Positives = 57/80 (71%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
+ ++ + +K++ + ++ K++ K++ T+ALGTSK+NYLDPRI+VAWCK+ V
Sbjct: 880 RDKVAKDKKQKQLERLREQLNKLELQETDKDENKTIALGTSKLNYLDPRISVAWCKKFGV 939
Query: 347 PIEKIFNKSLLAKFTWAMDV 288
PIEKIFNK+ KF WA+D+
Sbjct: 940 PIEKIFNKTQRDKFRWAIDM 959
[121][TOP]
>UniRef100_Q1ED17 Topoisomerase (DNA) I, like n=1 Tax=Danio rerio RepID=Q1ED17_DANRE
Length = 758
Score = 84.0 bits (206), Expect = 6e-15
Identities = 41/91 (45%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + EA +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 670 DEKFKKAV--EAKKKALQRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 727
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 728 KFGIPIEKIYNKTQREKFAWAIDMAEKDYEF 758
[122][TOP]
>UniRef100_Q75CB7 ACL008Cp n=1 Tax=Eremothecium gossypii RepID=Q75CB7_ASHGO
Length = 732
Score = 84.0 bits (206), Expect = 6e-15
Identities = 40/83 (48%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E L+ +I + +I MK KED +TVAL TSKI+Y+DPR++VA+CK+++VP+EK
Sbjct: 650 SVEKLKAQIDKLEQRIRTTSIQMKDKEDNSTVALSTSKISYIDPRLSVAFCKKYDVPLEK 709
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
+F K+L KF WA++ D ++RF
Sbjct: 710 VFTKTLREKFKWAIESADENWRF 732
[123][TOP]
>UniRef100_B6JVY3 DNA topoisomerase I n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6JVY3_SCHJY
Length = 654
Score = 84.0 bits (206), Expect = 6e-15
Identities = 37/82 (45%), Positives = 57/82 (69%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S+E LEK++ + + +I+ M + K++ T ALGTSKINY+DPR+T + CKR +PIEK
Sbjct: 573 SNEQLEKRLIKMDERIKVMSNSIIDKDENKTTALGTSKINYIDPRLTFSLCKRENIPIEK 632
Query: 335 IFNKSLLAKFTWAMDVDPDFRF 270
+F+K++ KF WA D D+ +
Sbjct: 633 LFSKTIRDKFNWAADTPADWNW 654
[124][TOP]
>UniRef100_B6H1W4 Pc13g03270 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6H1W4_PENCW
Length = 864
Score = 84.0 bits (206), Expect = 6e-15
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E LE I++ + ++E M + KED VALGTSKINY+DPR+TV + K+++VPIEK F
Sbjct: 784 EKLENSINKIDQRVETMSVQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKYDVPIEKFF 843
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+K+L KF WA+ VD D+ F
Sbjct: 844 SKALREKFEWAIKSVDEDWEF 864
[125][TOP]
>UniRef100_UPI0000F2B3E5 PREDICTED: similar to topoisomerase I n=1 Tax=Monodelphis domestica
RepID=UPI0000F2B3E5
Length = 916
Score = 83.6 bits (205), Expect = 8e-15
Identities = 41/91 (45%), Positives = 61/91 (67%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 828 DVKTKKVV--ETKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 885
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ D D+ F
Sbjct: 886 KWGIPIEKIYNKTQREKFAWAIDMADKDYEF 916
[126][TOP]
>UniRef100_UPI00017B27B1 UPI00017B27B1 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B1
Length = 751
Score = 83.6 bits (205), Expect = 8e-15
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 663 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 720
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 721 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 751
[127][TOP]
>UniRef100_UPI00017B27B0 UPI00017B27B0 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B27B0
Length = 751
Score = 83.6 bits (205), Expect = 8e-15
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 663 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 720
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 721 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 751
[128][TOP]
>UniRef100_Q4SR65 Chromosome 11 SCAF14528, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SR65_TETNG
Length = 806
Score = 83.6 bits (205), Expect = 8e-15
Identities = 40/91 (43%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 718 DEKSKKAVESK--KKAVQRIEDQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 775
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 776 KWGIPIEKIYNKTQREKFAWAIDMAEKDYEF 806
[129][TOP]
>UniRef100_Q6CUB9 KLLA0C06116p n=1 Tax=Kluyveromyces lactis RepID=Q6CUB9_KLULA
Length = 785
Score = 83.6 bits (205), Expect = 8e-15
Identities = 37/73 (50%), Positives = 54/73 (73%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E L++ + + +I +K KED +TVALGTSKINY+DPR++VA+CK+ +VPIEK+F
Sbjct: 705 EKLKQNVEKLEKRITNCSLQLKDKEDNSTVALGTSKINYIDPRLSVAFCKKFDVPIEKVF 764
Query: 329 NKSLLAKFTWAMD 291
K+L KF WA++
Sbjct: 765 TKTLRDKFRWAIE 777
[130][TOP]
>UniRef100_C4JVV4 DNA topoisomerase I n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JVV4_UNCRE
Length = 889
Score = 83.6 bits (205), Expect = 8e-15
Identities = 41/86 (47%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE +++ + +IE M + KE+ VALGTSKINY+DPR+TV + K+ +VP
Sbjct: 804 KGMTIEKLENNLAKLDQRIETMSLQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVP 863
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD D+ F
Sbjct: 864 IEKFFSKTLREKFDWAIKSVDEDWEF 889
[131][TOP]
>UniRef100_B0XN02 Topoisomerase I n=2 Tax=Aspergillus fumigatus RepID=B0XN02_ASPFC
Length = 998
Score = 83.6 bits (205), Expect = 8e-15
Identities = 44/86 (51%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K+ S E LE I++ +IE M+ + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 913 KSPSVEKLEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 972
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+KSL KF WA+ VD ++ F
Sbjct: 973 IEKFFSKSLREKFEWAIKSVDENWEF 998
[132][TOP]
>UniRef100_UPI000180B1AE PREDICTED: similar to DNA topoisomerase I, partial n=1 Tax=Ciona
intestinalis RepID=UPI000180B1AE
Length = 482
Score = 83.2 bits (204), Expect = 1e-14
Identities = 38/82 (46%), Positives = 55/82 (67%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E +KK+ + ++ K++ KE+ +ALGTSK+NYLDPRITVAWCK++ VP
Sbjct: 397 KRKAYEGKKKKVERLQEQLIKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKYSVP 456
Query: 344 IEKIFNKSLLAKFTWAMDVDPD 279
IEK +NK+ KF WA+ + D
Sbjct: 457 IEKCYNKTQRDKFAWAIAMVDD 478
[133][TOP]
>UniRef100_UPI0001760D92 PREDICTED: similar to topoisomerase (DNA) I, like n=1 Tax=Danio
rerio RepID=UPI0001760D92
Length = 748
Score = 83.2 bits (204), Expect = 1e-14
Identities = 41/91 (45%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E +K + + + ++ K++ +E+ +ALGTSK+NYLDPRI+V+WCK
Sbjct: 660 DEKSKKAV--ETKKKAVQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCK 717
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ VPIEKI++K+ KF WA+D+ D DF F
Sbjct: 718 KWGVPIEKIYSKTQRDKFAWAIDMADEDFEF 748
[134][TOP]
>UniRef100_B4MU44 GK23720 n=1 Tax=Drosophila willistoni RepID=B4MU44_DROWI
Length = 638
Score = 83.2 bits (204), Expect = 1e-14
Identities = 42/97 (43%), Positives = 63/97 (64%), Gaps = 9/97 (9%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAK--------IEKMQRDMKTKEDLNTVALGTSKINYLDPRI 378
K+ LS A +KKI++ K ++K++ + +E+ VAL TSK+NY+DPRI
Sbjct: 531 KRSATLSGTAKDKKIAECKGKQLERLKDQLKKLKLEETNREENKCVALTTSKLNYIDPRI 590
Query: 377 TVAWCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+VAWCK++ VPIEKIFNK+ KF WA+ + D ++ F
Sbjct: 591 SVAWCKKNNVPIEKIFNKTQRTKFLWAIHMADENYHF 627
[135][TOP]
>UniRef100_B3S6N7 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S6N7_TRIAD
Length = 560
Score = 83.2 bits (204), Expect = 1e-14
Identities = 40/88 (45%), Positives = 60/88 (68%), Gaps = 4/88 (4%)
Frame = -2
Query: 539 DGKKKKNLSSEAL----EKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITV 372
D K++K+ SS+ L +KK N ++ K+ K + VAL TSK+NY+DPRI+V
Sbjct: 466 DLKERKDESSKKLYEKRKKKTEMLNRQLHKLNLTETDKVENKEVALSTSKLNYMDPRISV 525
Query: 371 AWCKRHEVPIEKIFNKSLLAKFTWAMDV 288
AWCK++EVP+EK+FNK+ KF WA+++
Sbjct: 526 AWCKKNEVPVEKVFNKTQREKFKWAIEM 553
[136][TOP]
>UniRef100_A8Q2Z1 DNA topoisomerase I, putative n=1 Tax=Brugia malayi
RepID=A8Q2Z1_BRUMA
Length = 751
Score = 83.2 bits (204), Expect = 1e-14
Identities = 35/82 (42%), Positives = 56/82 (68%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K + + + K++ + ++ K++ K++ +AL TSK+NYLDPRI+VAWCK++
Sbjct: 663 KAHSDTAKQRATKRVDRVKEQLRKLKIQRTDKDENKQIALSTSKLNYLDPRISVAWCKKY 722
Query: 353 EVPIEKIFNKSLLAKFTWAMDV 288
+VPIEKIFNK+ KF WA+D+
Sbjct: 723 QVPIEKIFNKTQREKFRWAIDM 744
[137][TOP]
>UniRef100_Q6FVE9 Similar to uniprot|P04786 Saccharomyces cerevisiae YOL006c TOP1 DNA
topoisomerase I n=1 Tax=Candida glabrata
RepID=Q6FVE9_CANGA
Length = 717
Score = 83.2 bits (204), Expect = 1e-14
Identities = 42/83 (50%), Positives = 59/83 (71%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E LEK I + + +I Q ++ +E + V+LGTSKINY+DPR++V +CK++ VPIEK
Sbjct: 635 SVEKLEKAIERLDQRISTSQVQLQDREANSEVSLGTSKINYIDPRLSVVFCKKYGVPIEK 694
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
IF KSL KF WA++ VD +RF
Sbjct: 695 IFTKSLREKFKWAIESVDETWRF 717
[138][TOP]
>UniRef100_C5L755 DNA topoisomerase I, putative n=1 Tax=Perkinsus marinus ATCC 50983
RepID=C5L755_9ALVE
Length = 647
Score = 82.8 bits (203), Expect = 1e-14
Identities = 41/88 (46%), Positives = 58/88 (65%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K +K+ + ++L +KI E+ + + KED TV+L TSKINY+DPRI+VA+CK H
Sbjct: 560 KLEKSNNMDSLVRKIKSQKLAAERTKIQIADKEDNKTVSLTTSKINYMDPRISVAFCKSH 619
Query: 353 EVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
+ PIEKIF K++ KF WAM +RF
Sbjct: 620 DCPIEKIFAKTIRNKFPWAMHSKSTWRF 647
[139][TOP]
>UniRef100_Q875K2 Topoisomerase I n=1 Tax=Emericella nidulans RepID=Q875K2_EMENI
Length = 871
Score = 82.8 bits (203), Expect = 1e-14
Identities = 42/81 (51%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E LE I++ +IE M+ + KED VALGTSKINY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+KSL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[140][TOP]
>UniRef100_O13463 Topoisomerase I n=1 Tax=Emericella nidulans RepID=O13463_EMENI
Length = 871
Score = 82.8 bits (203), Expect = 1e-14
Identities = 42/81 (51%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E LE I++ +IE M+ + KED VALGTSKINY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+KSL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[141][TOP]
>UniRef100_C8VUK1 Topoisomerase I [Source:UniProtKB/TrEMBL;Acc:Q875K2] n=2
Tax=Emericella nidulans RepID=C8VUK1_EMENI
Length = 871
Score = 82.8 bits (203), Expect = 1e-14
Identities = 42/81 (51%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E LE I++ +IE M+ + KED VALGTSKINY+DPR+TV + K+ +VPIEK F
Sbjct: 791 EKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFF 850
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+KSL KF WA+ VD ++ F
Sbjct: 851 SKSLREKFEWAIKSVDENWEF 871
[142][TOP]
>UniRef100_C7GJV8 Top1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GJV8_YEAS2
Length = 745
Score = 82.8 bits (203), Expect = 1e-14
Identities = 38/83 (45%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E ++ ++ + +I+ +K KE+ + V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 663 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 722
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
IF K+L KF WA++ VD ++RF
Sbjct: 723 IFTKTLREKFKWAIESVDENWRF 745
[143][TOP]
>UniRef100_B3LJ50 DNA topoisomerase I n=2 Tax=Saccharomyces cerevisiae
RepID=B3LJ50_YEAS1
Length = 769
Score = 82.8 bits (203), Expect = 1e-14
Identities = 38/83 (45%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E ++ ++ + +I+ +K KE+ + V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
IF K+L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[144][TOP]
>UniRef100_P04786 DNA topoisomerase 1 n=3 Tax=Saccharomyces cerevisiae
RepID=TOP1_YEAST
Length = 769
Score = 82.8 bits (203), Expect = 1e-14
Identities = 38/83 (45%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
Frame = -2
Query: 515 SSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
S E ++ ++ + +I+ +K KE+ + V+LGTSKINY+DPR++V +CK+++VPIEK
Sbjct: 687 SVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEK 746
Query: 335 IFNKSLLAKFTWAMD-VDPDFRF 270
IF K+L KF WA++ VD ++RF
Sbjct: 747 IFTKTLREKFKWAIESVDENWRF 769
[145][TOP]
>UniRef100_Q2URN8 DNA topoisomerase I n=1 Tax=Aspergillus oryzae RepID=Q2URN8_ASPOR
Length = 881
Score = 82.4 bits (202), Expect = 2e-14
Identities = 43/86 (50%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE I + +IE M+ + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 796 KGPTVEKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 855
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+KSL KF WA+ V+ D+ F
Sbjct: 856 IEKFFSKSLREKFEWAIKSVEQDWEF 881
[146][TOP]
>UniRef100_B8MY66 Topoisomerase I n=1 Tax=Aspergillus flavus NRRL3357
RepID=B8MY66_ASPFN
Length = 881
Score = 82.4 bits (202), Expect = 2e-14
Identities = 43/86 (50%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE I + +IE M+ + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 796 KGPTVEKLENAIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 855
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+KSL KF WA+ V+ D+ F
Sbjct: 856 IEKFFSKSLREKFEWAIKSVEQDWEF 881
[147][TOP]
>UniRef100_A1D4R5 Topoisomerase I n=1 Tax=Neosartorya fischeri NRRL 181
RepID=A1D4R5_NEOFI
Length = 886
Score = 82.4 bits (202), Expect = 2e-14
Identities = 43/86 (50%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K+ S E LE I++ +IE M+ + KE+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 801 KSSSVEKLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVP 860
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+KSL KF WA+ VD ++ F
Sbjct: 861 IEKFFSKSLREKFEWAIKSVDENWEF 886
[148][TOP]
>UniRef100_Q7QH57 AGAP004078-PA n=1 Tax=Anopheles gambiae RepID=Q7QH57_ANOGA
Length = 969
Score = 82.0 bits (201), Expect = 2e-14
Identities = 35/70 (50%), Positives = 53/70 (75%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K++ + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+ VPIEKIFNK+
Sbjct: 893 KQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQ 952
Query: 317 LAKFTWAMDV 288
KF WA+D+
Sbjct: 953 RDKFRWAIDM 962
[149][TOP]
>UniRef100_C6HAF8 Topoisomerase I n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HAF8_AJECH
Length = 909
Score = 82.0 bits (201), Expect = 2e-14
Identities = 41/86 (47%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + + +IE M + KE+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 824 KGITIEKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVP 883
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD D+ F
Sbjct: 884 IEKFFSKTLREKFDWAIKSVDEDWEF 909
[150][TOP]
>UniRef100_C0NC53 Topoisomerase I n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NC53_AJECG
Length = 909
Score = 82.0 bits (201), Expect = 2e-14
Identities = 41/86 (47%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + + +IE M + KE+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 824 KGITIEKLENQLLKLSQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSKKFNVP 883
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD D+ F
Sbjct: 884 IEKFFSKTLREKFDWAIKSVDEDWEF 909
[151][TOP]
>UniRef100_A3LUX2 DNA topoisomerase I n=1 Tax=Pichia stipitis RepID=A3LUX2_PICST
Length = 780
Score = 82.0 bits (201), Expect = 2e-14
Identities = 40/87 (45%), Positives = 61/87 (70%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
KKNL+ E L++++ +I +K KED + V+LGTSK+NY+DPR+TV + K+ +V
Sbjct: 694 KKNLTVEKLQQQVEVIENRIVTTTLQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDV 753
Query: 347 PIEKIFNKSLLAKFTWAMD-VDPDFRF 270
PIEK+F K+L KF WA++ D ++RF
Sbjct: 754 PIEKLFTKTLRDKFKWAIESADENWRF 780
[152][TOP]
>UniRef100_P79994 DNA topoisomerase I n=2 Tax=Gallus gallus RepID=P79994_CHICK
Length = 766
Score = 81.6 bits (200), Expect = 3e-14
Identities = 39/91 (42%), Positives = 61/91 (67%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +AL TSK+NYLDPRI+VAWCK
Sbjct: 678 DEKSKKAVESK--KKAVQRIEEQLMKLEVQATDREENKQIALSTSKLNYLDPRISVAWCK 735
Query: 359 RHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
+ +PIEKI+NK+ KF WA+D+ + D+ F
Sbjct: 736 KWGIPIEKIYNKTQREKFAWAIDMAEEDYEF 766
[153][TOP]
>UniRef100_Q0CUT4 DNA topoisomerase I n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CUT4_ASPTN
Length = 872
Score = 81.6 bits (200), Expect = 3e-14
Identities = 41/81 (50%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E +E I + +IE M+ + KED VALGTSKINY+DPR+TV + K+ VPIEK F
Sbjct: 792 EKIEANIQKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFF 851
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+K+L KF WA+ VD D+ F
Sbjct: 852 SKALREKFEWAIKSVDEDWEF 872
[154][TOP]
>UniRef100_Q94705 DNA topoisomerase I n=1 Tax=Physarum polycephalum RepID=Q94705_PHYPO
Length = 1015
Score = 81.3 bits (199), Expect = 4e-14
Identities = 43/91 (47%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Frame = -2
Query: 533 KKKKNLSSEALEK---KISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
KK K +++EK I + + I K K++L +VAL TSKINY+DPRIT AW
Sbjct: 925 KKVKRALPDSVEKCKAAIERVDTSINKWNIKKTEKDELKSVALTTSKINYIDPRITAAWA 984
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDVDPDFRF 270
KR + I K+F+KSL KF WAMDV+ D+ F
Sbjct: 985 KRVGLDIGKLFSKSLREKFPWAMDVEEDWEF 1015
[155][TOP]
>UniRef100_UPI00017968A4 PREDICTED: similar to TOP1MT protein n=1 Tax=Equus caballus
RepID=UPI00017968A4
Length = 655
Score = 80.9 bits (198), Expect = 5e-14
Identities = 37/81 (45%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E E+ + + ++ ++ KE+ VALGTSK+NYLDPRI+VAWCKR VP+E+I+
Sbjct: 575 EKRERLLEKLEEQLMRLSTQATDKEESKQVALGTSKLNYLDPRISVAWCKRFGVPVERIY 634
Query: 329 NKSLLAKFTWAMDV-DPDFRF 270
NK+ +F WA+D+ DF F
Sbjct: 635 NKTQRERFAWALDMAGEDFEF 655
[156][TOP]
>UniRef100_UPI000176075D PREDICTED: similar to DNA topoisomerase I n=1 Tax=Danio rerio
RepID=UPI000176075D
Length = 531
Score = 80.9 bits (198), Expect = 5e-14
Identities = 38/81 (46%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E +K + + ++ KM+ +E+ +AL TSK+NYLDPRI+VAWCK EVP++KI+
Sbjct: 451 EKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIY 510
Query: 329 NKSLLAKFTWAMDV-DPDFRF 270
NK+L KF WA+D+ + DF F
Sbjct: 511 NKTLRDKFAWAVDMTELDFVF 531
[157][TOP]
>UniRef100_UPI0000E48333 PREDICTED: similar to topoisomerase I alpha isoform 3, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48333
Length = 440
Score = 80.9 bits (198), Expect = 5e-14
Identities = 42/83 (50%), Positives = 59/83 (71%), Gaps = 4/83 (4%)
Frame = -2
Query: 506 ALEKKISQTNAKIEKMQR-DMKT--KEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
A+EKK Q +E++ + +MK KE+ +ALGTSK+NYLDPRI+VAW K+ +VPIEK
Sbjct: 358 AMEKKAKQVERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEK 417
Query: 335 IFNKSLLAKFTWAMDV-DPDFRF 270
++NK+ KF WA+D+ DF F
Sbjct: 418 VYNKTQRDKFRWAVDMAGADFVF 440
[158][TOP]
>UniRef100_UPI0000E471B7 PREDICTED: similar to topoisomerase I beta n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI0000E471B7
Length = 879
Score = 80.9 bits (198), Expect = 5e-14
Identities = 42/83 (50%), Positives = 59/83 (71%), Gaps = 4/83 (4%)
Frame = -2
Query: 506 ALEKKISQTNAKIEKMQR-DMKT--KEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
A+EKK Q +E++ + +MK KE+ +ALGTSK+NYLDPRI+VAW K+ +VPIEK
Sbjct: 797 AMEKKAKQVERLVEQLAKLEMKATDKEENKEIALGTSKLNYLDPRISVAWTKKWDVPIEK 856
Query: 335 IFNKSLLAKFTWAMDV-DPDFRF 270
++NK+ KF WA+D+ DF F
Sbjct: 857 VYNKTQRDKFRWAVDMAGADFVF 879
[159][TOP]
>UniRef100_UPI0001A2C88D UPI0001A2C88D related cluster n=1 Tax=Danio rerio
RepID=UPI0001A2C88D
Length = 609
Score = 80.9 bits (198), Expect = 5e-14
Identities = 38/81 (46%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E +K + + ++ KM+ +E+ +AL TSK+NYLDPRI+VAWCK EVP++KI+
Sbjct: 529 EKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIY 588
Query: 329 NKSLLAKFTWAMDV-DPDFRF 270
NK+L KF WA+D+ + DF F
Sbjct: 589 NKTLRDKFAWAVDMTELDFVF 609
[160][TOP]
>UniRef100_Q6C7R2 YALI0D26103p n=1 Tax=Yarrowia lipolytica RepID=Q6C7R2_YARLI
Length = 760
Score = 80.9 bits (198), Expect = 5e-14
Identities = 37/81 (45%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E L ++ + ++ M+ +K KED ++VALGTSK+NY+DPR+TV + K+++VPIEK+F
Sbjct: 680 EKLRAQVEKLETRVTTMRMQLKDKEDNSSVALGTSKMNYIDPRLTVKFSKKYDVPIEKLF 739
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
K+L KF WA+ D D+ F
Sbjct: 740 TKTLRDKFQWAIQSADEDWEF 760
[161][TOP]
>UniRef100_O59891 Topoisomerase I n=1 Tax=Cryptococcus neoformans var. neoformans
RepID=O59891_CRYNE
Length = 844
Score = 80.9 bits (198), Expect = 5e-14
Identities = 38/87 (43%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K+ + E L +I++ + +I + ++ ++ L VALGTSKINY+DPR+TVAW K+ +V
Sbjct: 758 KRGATEEKLLAQIARIDERIATAKVQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDV 817
Query: 347 PIEKIFNKSLLAKFTWA-MDVDPDFRF 270
P+EK+F+K+L KF WA + PD+ F
Sbjct: 818 PLEKLFSKTLREKFPWAEAEAGPDWVF 844
[162][TOP]
>UniRef100_B8MH68 Topoisomerase I n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8MH68_TALSN
Length = 864
Score = 80.9 bits (198), Expect = 5e-14
Identities = 41/86 (47%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE +++ +IE M + KE+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 779 KGQTIEKLENNVAKLEQRIETMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVP 838
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD D+ F
Sbjct: 839 IEKFFSKTLREKFDWAIKSVDEDWEF 864
[163][TOP]
>UniRef100_A2Q8K2 Catalytic activity: ATP-independent breakage of single-stranded DNA
n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2Q8K2_ASPNC
Length = 884
Score = 80.9 bits (198), Expect = 5e-14
Identities = 40/81 (49%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
+ +E I++ +IE M+ + KE+ VALGTSKINY+DPR+TV + K+ +VPIEK F
Sbjct: 804 DKIEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFF 863
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+KSL KF WA+ VD D+ F
Sbjct: 864 SKSLREKFEWAIKSVDEDWEF 884
[164][TOP]
>UniRef100_Q5KB99 Topoisomerase I n=1 Tax=Filobasidiella neoformans RepID=Q5KB99_CRYNE
Length = 881
Score = 80.5 bits (197), Expect = 7e-14
Identities = 37/87 (42%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K+ + E L ++++ + +I + ++ ++ L VALGTSKINY+DPR+TVAW K+ +V
Sbjct: 795 KRGATEEKLLAQVARIDERIATAKVQLQDRDKLKDVALGTSKINYIDPRLTVAWAKKFDV 854
Query: 347 PIEKIFNKSLLAKFTWA-MDVDPDFRF 270
P+EK+F+K+L KF WA + PD+ F
Sbjct: 855 PLEKLFSKTLREKFPWAEAEAGPDWVF 881
[165][TOP]
>UniRef100_A1CRV8 Topoisomerase I n=1 Tax=Aspergillus clavatus RepID=A1CRV8_ASPCL
Length = 886
Score = 80.5 bits (197), Expect = 7e-14
Identities = 42/86 (48%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K+ S +E I++ +IE M+ + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 801 KSPSVARIEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVP 860
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+KSL KF WA+ VD ++ F
Sbjct: 861 IEKFFSKSLREKFEWAIKSVDENWEF 886
[166][TOP]
>UniRef100_O60013 DNA topoisomerase I n=1 Tax=Pneumocystis carinii RepID=O60013_PNECA
Length = 763
Score = 80.1 bits (196), Expect = 9e-14
Identities = 37/87 (42%), Positives = 54/87 (62%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
K + ++ E L+ +I + N +I +M+ M K T ALGTSKINY+DPR+T AWC ++
Sbjct: 677 KTRGITIETLDLQIKKINERIHQMKALMIDKAQNKTTALGTSKINYIDPRLTYAWCAKYG 736
Query: 350 VPIEKIFNKSLLAKFTWAMDVDPDFRF 270
V IE++F K+L F WA D+ F
Sbjct: 737 VNIERVFTKTLRETFAWAASTTADWEF 763
[167][TOP]
>UniRef100_B9WIH6 DNA topoisomerase, putative n=1 Tax=Candida dubliniensis CD36
RepID=B9WIH6_CANDC
Length = 777
Score = 80.1 bits (196), Expect = 9e-14
Identities = 39/86 (45%), Positives = 60/86 (69%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
KN + E L+++I +I + +K KED + V+LGTSK+NY+DPR+TV + K+ +VP
Sbjct: 692 KNATVEKLKQQIETLENRILNVSFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 751
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D ++RF
Sbjct: 752 IEKLFTKTLREKFNWAIESTDENWRF 777
[168][TOP]
>UniRef100_UPI00017B3173 UPI00017B3173 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B3173
Length = 622
Score = 79.7 bits (195), Expect = 1e-13
Identities = 37/85 (43%), Positives = 56/85 (65%), Gaps = 2/85 (2%)
Frame = -2
Query: 536 GKKKKNLSSEALEKK--ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
G L + + KK + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWC
Sbjct: 531 GSADAKLQALVVRKKMAVKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWC 590
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV 288
K+ EVP++KI+NKS KF WA+D+
Sbjct: 591 KKMEVPVDKIYNKSQRDKFAWAIDM 615
[169][TOP]
>UniRef100_Q4SKE8 Chromosome 13 SCAF14566, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4SKE8_TETNG
Length = 622
Score = 79.7 bits (195), Expect = 1e-13
Identities = 37/85 (43%), Positives = 56/85 (65%), Gaps = 2/85 (2%)
Frame = -2
Query: 536 GKKKKNLSSEALEKK--ISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
G L + + KK + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWC
Sbjct: 531 GSADAKLQALVVRKKMAVKRCEEQLLKLEVQATDREENKQIALGTSKLNYLDPRISVAWC 590
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV 288
K+ EVP++KI+NKS KF WA+D+
Sbjct: 591 KKMEVPVDKIYNKSQRDKFAWAIDM 615
[170][TOP]
>UniRef100_C4XZS7 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4XZS7_CLAL4
Length = 764
Score = 79.7 bits (195), Expect = 1e-13
Identities = 40/86 (46%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K S E L+ +I + +I +K KED + V+LGTSK+NY+DPR+TV + K+ VP
Sbjct: 679 KGASVEKLKVQIEKIENRILNTNFQLKDKEDNSEVSLGTSKLNYIDPRLTVMFAKKFNVP 738
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KFTWA++ D ++RF
Sbjct: 739 IEKLFTKTLREKFTWAIESADENWRF 764
[171][TOP]
>UniRef100_B6QNQ2 Topoisomerase I n=1 Tax=Penicillium marneffei ATCC 18224
RepID=B6QNQ2_PENMQ
Length = 860
Score = 79.7 bits (195), Expect = 1e-13
Identities = 40/86 (46%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE +++ +IE M + KE+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 775 KGQTVEKLENNVTKLEQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVP 834
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ V+ D+ F
Sbjct: 835 IEKFFSKTLREKFDWAIKSVEEDWEF 860
[172][TOP]
>UniRef100_C5GB81 DNA topoisomerase I n=2 Tax=Ajellomyces dermatitidis
RepID=C5GB81_AJEDR
Length = 911
Score = 79.0 bits (193), Expect = 2e-13
Identities = 39/86 (45%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + + +IE M + +E+ VALGTSKINY+DPR+TV + K+ VP
Sbjct: 826 KGVTIEKLENQLLKLSQRIENMSLQAEDRENNKEVALGTSKINYIDPRLTVVFSKKFNVP 885
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ V+ D+ F
Sbjct: 886 IEKFFSKTLREKFDWAIKSVEEDWEF 911
[173][TOP]
>UniRef100_Q4V7M4 MGC115546 protein n=1 Tax=Xenopus laevis RepID=Q4V7M4_XENLA
Length = 503
Score = 78.6 bits (192), Expect = 3e-13
Identities = 37/88 (42%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
+K N E+ ++ + +T ++ +M+ +E+ +AL TSK+NYLDPRI+VAWCK+
Sbjct: 416 EKLNKVVESKKRAVQRTEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWT 475
Query: 350 VPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
V +EKI+NK+ KF WA+D+ + DF F
Sbjct: 476 VGLEKIYNKTYRDKFAWAIDMTETDFIF 503
[174][TOP]
>UniRef100_B3GD31 Topoisomerase I (Fragment) n=1 Tax=Sirdenus grayii
RepID=B3GD31_9CARA
Length = 247
Score = 78.6 bits (192), Expect = 3e-13
Identities = 35/77 (45%), Positives = 55/77 (71%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ L E +K + + +++K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKLVYEKKKKMLDKLKDQLKKLEVQETDRDENKTIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[175][TOP]
>UniRef100_Q59XR0 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59XR0_CANAL
Length = 780
Score = 78.6 bits (192), Expect = 3e-13
Identities = 39/86 (45%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
KN + E L+++I KI + +K KED + V+LGTSK+NY+DPR+ V + K+ +VP
Sbjct: 695 KNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 754
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D ++RF
Sbjct: 755 IEKLFTKTLREKFIWAIESADENWRF 780
[176][TOP]
>UniRef100_Q59WV6 Likely DNA topoisomerase I n=1 Tax=Candida albicans
RepID=Q59WV6_CANAL
Length = 780
Score = 78.6 bits (192), Expect = 3e-13
Identities = 39/86 (45%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
KN + E L+++I KI + +K KED + V+LGTSK+NY+DPR+ V + K+ +VP
Sbjct: 695 KNATVEKLKQQIETLENKILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 754
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D ++RF
Sbjct: 755 IEKLFTKTLREKFIWAIESADENWRF 780
[177][TOP]
>UniRef100_Q1DXZ1 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1DXZ1_COCIM
Length = 905
Score = 78.2 bits (191), Expect = 3e-13
Identities = 39/86 (45%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E E +++ + +I+ M + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVP 879
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[178][TOP]
>UniRef100_C5P0Y8 DNA topoisomerase I, putative n=1 Tax=Coccidioides posadasii C735
delta SOWgp RepID=C5P0Y8_COCP7
Length = 905
Score = 78.2 bits (191), Expect = 3e-13
Identities = 39/86 (45%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E E +++ + +I+ M + KED VALGTSKINY+DPR+TV + K+ VP
Sbjct: 820 KGATIEKYENNLAKLDQRIDTMSLQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFSVP 879
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[179][TOP]
>UniRef100_C5FTA8 DNA topoisomerase 1 n=1 Tax=Microsporum canis CBS 113480
RepID=C5FTA8_NANOT
Length = 896
Score = 78.2 bits (191), Expect = 3e-13
Identities = 39/81 (48%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 330
E E +IS+ + +IE M + KE+ VALGTSK+NY+DPR+TV + K+ VPIEK F
Sbjct: 816 EKFEGQISKIDQRIENMLLQAEDKENNKEVALGTSKLNYIDPRLTVVFSKKFNVPIEKFF 875
Query: 329 NKSLLAKFTWAM-DVDPDFRF 270
+K++ KF WA+ VD D+ F
Sbjct: 876 SKTMREKFDWAIKSVDEDWEF 896
[180][TOP]
>UniRef100_A5E508 DNA topoisomerase I n=1 Tax=Lodderomyces elongisporus
RepID=A5E508_LODEL
Length = 849
Score = 78.2 bits (191), Expect = 3e-13
Identities = 38/86 (44%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E L+ ++ +I +K KED + V+LGTSK+NY+DPR+TV + K+ +VP
Sbjct: 764 KGATVEKLKTQVENMENRIVSTTLQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 823
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D D+RF
Sbjct: 824 IEKLFTKTLREKFKWAIESTDKDWRF 849
[181][TOP]
>UniRef100_UPI00016E5A49 UPI00016E5A49 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A49
Length = 692
Score = 77.8 bits (190), Expect = 5e-13
Identities = 39/94 (41%), Positives = 60/94 (63%), Gaps = 7/94 (7%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKT------KEDLNTVALGTSKINYLDPRITVA 369
K K S L+ + + A +++ ++ +K +E+ +ALGTSK+NYLDPRI+VA
Sbjct: 599 KAKGSSEFKLQTLVERKKAAVKRCEQLLKMEIQATDREENKQIALGTSKLNYLDPRISVA 658
Query: 368 WCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
WCK +P++KI+NKS KF WA+D+ + DF F
Sbjct: 659 WCKNMGLPVDKIYNKSQRDKFAWAIDMTEVDFEF 692
[182][TOP]
>UniRef100_UPI00016E5A48 UPI00016E5A48 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5A48
Length = 632
Score = 77.8 bits (190), Expect = 5e-13
Identities = 39/94 (41%), Positives = 60/94 (63%), Gaps = 7/94 (7%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKT------KEDLNTVALGTSKINYLDPRITVA 369
K K S L+ + + A +++ ++ +K +E+ +ALGTSK+NYLDPRI+VA
Sbjct: 539 KAKGSSEFKLQTLVERKKAAVKRCEQLLKMEIQATDREENKQIALGTSKLNYLDPRISVA 598
Query: 368 WCKRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
WCK +P++KI+NKS KF WA+D+ + DF F
Sbjct: 599 WCKNMGLPVDKIYNKSQRDKFAWAIDMTEVDFEF 632
[183][TOP]
>UniRef100_B2WCA4 DNA topoisomerase 1 n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WCA4_PYRTR
Length = 905
Score = 77.8 bits (190), Expect = 5e-13
Identities = 41/86 (47%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE + + +IE M+ M+ KE VALGTSKINY+DPR+TV + K+ VP
Sbjct: 820 KGPTVEKLEANVEKIVQRIENMKIQMEDKEGNKEVALGTSKINYIDPRLTVVFSKKFGVP 879
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
IEK F+K+L KF WA+ VD ++ F
Sbjct: 880 IEKFFSKTLREKFDWAIKSVDENWEF 905
[184][TOP]
>UniRef100_Q8TBP3 TOP1MT protein (Fragment) n=1 Tax=Homo sapiens RepID=Q8TBP3_HUMAN
Length = 101
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 13 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 69
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 70 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 101
[185][TOP]
>UniRef100_B7ZAR5 cDNA, FLJ79279, highly similar to DNA topoisomerase I,
mitochondrial(EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7ZAR5_HUMAN
Length = 503
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRWLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[186][TOP]
>UniRef100_B7Z9E8 cDNA, FLJ78812, highly similar to DNA topoisomerase I,
mitochondrial (EC 5.99.1.2) n=1 Tax=Homo sapiens
RepID=B7Z9E8_HUMAN
Length = 503
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRWLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[187][TOP]
>UniRef100_B4DYD2 cDNA FLJ50294, highly similar to DNA topoisomerase I, mitochondrial
(EC 5.99.1.2) n=1 Tax=Homo sapiens RepID=B4DYD2_HUMAN
Length = 503
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 415 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 471
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 472 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 503
[188][TOP]
>UniRef100_Q00313 DNA topoisomerase 1 n=1 Tax=Candida albicans RepID=TOP1_CANAL
Length = 778
Score = 77.4 bits (189), Expect = 6e-13
Identities = 38/86 (44%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
KN + E L+++I +I + +K KED + V+LGTSK+NY+DPR+ V + K+ +VP
Sbjct: 693 KNATVEKLKQQIETLENRILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVP 752
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D ++RF
Sbjct: 753 IEKLFTKTLREKFIWAIESADENWRF 778
[189][TOP]
>UniRef100_A9Q1D5 DNA topoisomerase I, mitochondrial n=1 Tax=Pan troglodytes
RepID=TOP1M_PANTR
Length = 601
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 513 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 569
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 570 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
[190][TOP]
>UniRef100_Q969P6 DNA topoisomerase I, mitochondrial n=1 Tax=Homo sapiens
RepID=TOP1M_HUMAN
Length = 601
Score = 77.4 bits (189), Expect = 6e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)
Frame = -2
Query: 539 DGKKKKNLSSEA-LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWC 363
DGK + L + L +K+ + A++ D KE+ VALGTSK+NYLDPRI++AWC
Sbjct: 513 DGKSRSVLEKKRRLLEKLQEQLAQLSVQATD---KEENKQVALGTSKLNYLDPRISIAWC 569
Query: 362 KRHEVPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
KR VP+EKI++K+ +F WA+ + DF F
Sbjct: 570 KRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
[191][TOP]
>UniRef100_B3GD23 Topoisomerase I (Fragment) n=1 Tax=Laccophilus pictus
RepID=B3GD23_9DYTI
Length = 247
Score = 77.0 bits (188), Expect = 8e-13
Identities = 33/77 (42%), Positives = 55/77 (71%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ L + +K + + +++K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKLVHDKKKKSLDRLKEQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[192][TOP]
>UniRef100_C5M985 DNA topoisomerase I n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M985_CANTT
Length = 777
Score = 77.0 bits (188), Expect = 8e-13
Identities = 39/86 (45%), Positives = 58/86 (67%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
KN + E L+ +I +I +K KED + V+LGTSK+NY+DPR+TV + K+ +VP
Sbjct: 692 KNATVEKLKGQIETLENRILTTSFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFDVP 751
Query: 344 IEKIFNKSLLAKFTWAMD-VDPDFRF 270
IEK+F K+L KF WA++ D ++RF
Sbjct: 752 IEKLFTKTLRDKFKWAIESTDENWRF 777
[193][TOP]
>UniRef100_C1H484 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1H484_PARBA
Length = 900
Score = 77.0 bits (188), Expect = 8e-13
Identities = 38/86 (44%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + +IE M + KE+ VALGTSKINY+DPR+TV + ++ VP
Sbjct: 815 KGVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVP 874
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
+EK F+K+L KF WA+ VD ++ F
Sbjct: 875 MEKFFSKTLREKFDWAIKSVDENWEF 900
[194][TOP]
>UniRef100_C1GKM6 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1GKM6_PARBD
Length = 825
Score = 77.0 bits (188), Expect = 8e-13
Identities = 38/86 (44%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + +IE M + KE+ VALGTSKINY+DPR+TV + ++ VP
Sbjct: 740 KGVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVP 799
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
+EK F+K+L KF WA+ VD ++ F
Sbjct: 800 MEKFFSKTLREKFDWAIKSVDENWEF 825
[195][TOP]
>UniRef100_C0SEQ3 DNA topoisomerase n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0SEQ3_PARBP
Length = 905
Score = 77.0 bits (188), Expect = 8e-13
Identities = 38/86 (44%), Positives = 57/86 (66%), Gaps = 1/86 (1%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K ++ E LE ++ + +IE M + KE+ VALGTSKINY+DPR+TV + ++ VP
Sbjct: 820 KGVTVEKLENQLLKLGQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFSRKFNVP 879
Query: 344 IEKIFNKSLLAKFTWAM-DVDPDFRF 270
+EK F+K+L KF WA+ VD ++ F
Sbjct: 880 MEKFFSKTLREKFDWAIKSVDENWEF 905
[196][TOP]
>UniRef100_UPI00003BE191 hypothetical protein DEHA0F10945g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE191
Length = 789
Score = 76.6 bits (187), Expect = 1e-12
Identities = 37/87 (42%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
KK+++ E L+ ++ +I +K KED + V+LGTSK+NY+DPR+TV + K+ V
Sbjct: 703 KKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNV 762
Query: 347 PIEKIFNKSLLAKFTWAMD-VDPDFRF 270
PIEK+F K+L KF WA++ D +++F
Sbjct: 763 PIEKLFTKTLRDKFNWAIESADENWKF 789
[197][TOP]
>UniRef100_UPI000069E294 DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I). n=1
Tax=Xenopus (Silurana) tropicalis RepID=UPI000069E294
Length = 786
Score = 76.6 bits (187), Expect = 1e-12
Identities = 38/85 (44%), Positives = 56/85 (65%), Gaps = 3/85 (3%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 696 DEKSKKLVESK--KKAVQRVEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 753
Query: 359 RHEVPIEKIFNK---SLLAKFTWAM 294
++ +PIEKI+NK SLL W M
Sbjct: 754 KYGIPIEKIYNKTQRSLLGPLIWRM 778
[198][TOP]
>UniRef100_Q6BLX2 DEHA2F09988p n=1 Tax=Debaryomyces hansenii RepID=Q6BLX2_DEBHA
Length = 789
Score = 76.6 bits (187), Expect = 1e-12
Identities = 37/87 (42%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
KK+++ E L+ ++ +I +K KED + V+LGTSK+NY+DPR+TV + K+ V
Sbjct: 703 KKSVTVEKLKSQVDTLTNRILNTTFQLKDKEDNSEVSLGTSKMNYIDPRLTVMFSKKFNV 762
Query: 347 PIEKIFNKSLLAKFTWAMD-VDPDFRF 270
PIEK+F K+L KF WA++ D +++F
Sbjct: 763 PIEKLFTKTLRDKFNWAIESADENWKF 789
[199][TOP]
>UniRef100_Q6IM78 DNA topoisomerase I, mitochondrial n=1 Tax=Rattus norvegicus
RepID=TOP1M_RAT
Length = 593
Score = 76.6 bits (187), Expect = 1e-12
Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K K L + K+ + A++ D KE+ VALGT+K+NYLDPRI++AWCK
Sbjct: 506 DSKSKSFLQKQQRLLKLEEQLARLCTKATD---KEENKQVALGTAKLNYLDPRISIAWCK 562
Query: 359 RHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
R VP+EKI+NK+ +F WA + DF F
Sbjct: 563 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593
[200][TOP]
>UniRef100_UPI000069F011 UPI000069F011 related cluster n=1 Tax=Xenopus (Silurana) tropicalis
RepID=UPI000069F011
Length = 503
Score = 76.3 bits (186), Expect = 1e-12
Identities = 36/88 (40%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
+K N E+ ++ + + ++ +M+ +E+ +AL TSK+NYLDPRI+VAWCK+
Sbjct: 416 EKLNKVVESKKRGVQRAEEQLMRMEVQATDREENKQIALSTSKLNYLDPRISVAWCKKWT 475
Query: 350 VPIEKIFNKSLLAKFTWAMDV-DPDFRF 270
V +EKI+NK+ KF WA+D+ + DF F
Sbjct: 476 VGLEKIYNKTYRDKFAWAVDMTETDFIF 503
[201][TOP]
>UniRef100_Q9D6H0 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q9D6H0_MOUSE
Length = 295
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K K L + K+ + A++ D KE+ VALGT+K+NYLDPRI++AWCK
Sbjct: 208 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 264
Query: 359 RHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
R VP+EKI+NK+ +F WA + DF F
Sbjct: 265 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 295
[202][TOP]
>UniRef100_B7ZNM9 Top1mt protein n=1 Tax=Mus musculus RepID=B7ZNM9_MOUSE
Length = 592
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K K L + K+ + A++ D KE+ VALGT+K+NYLDPRI++AWCK
Sbjct: 505 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 561
Query: 359 RHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
R VP+EKI+NK+ +F WA + DF F
Sbjct: 562 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 592
[203][TOP]
>UniRef100_C4R3Z3 Topoisomerase I n=1 Tax=Pichia pastoris GS115 RepID=C4R3Z3_PICPG
Length = 763
Score = 76.3 bits (186), Expect = 1e-12
Identities = 34/80 (42%), Positives = 55/80 (68%)
Frame = -2
Query: 530 KKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHE 351
K ++ E LE ++ + +I ++ KED + VALGTSK+NY+DPR+T + K+++
Sbjct: 676 KSVTVTVEKLESQVEKLEQRIRNATLLLQDKEDNSQVALGTSKLNYIDPRLTAMFSKKYD 735
Query: 350 VPIEKIFNKSLLAKFTWAMD 291
VPIEK+F+K+L KF WA++
Sbjct: 736 VPIEKLFSKTLREKFAWAIE 755
[204][TOP]
>UniRef100_Q8R4U6 DNA topoisomerase I, mitochondrial n=1 Tax=Mus musculus
RepID=TOP1M_MOUSE
Length = 593
Score = 76.3 bits (186), Expect = 1e-12
Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K K L + K+ + A++ D KE+ VALGT+K+NYLDPRI++AWCK
Sbjct: 506 DSKPKSFLQKQRRLLKLEEQLARLCAKATD---KEENKQVALGTAKLNYLDPRISIAWCK 562
Query: 359 RHEVPIEKIFNKSLLAKFTWAMD-VDPDFRF 270
R VP+EKI+NK+ +F WA + DF F
Sbjct: 563 RFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593
[205][TOP]
>UniRef100_UPI000151AE34 hypothetical protein PGUG_04275 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AE34
Length = 754
Score = 75.9 bits (185), Expect = 2e-12
Identities = 36/87 (41%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K + E L+ ++ + + +I ++ KED + V+LGTSK+NY+DPR+TV + K+ +V
Sbjct: 668 KSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDV 727
Query: 347 PIEKIFNKSLLAKFTWAMD-VDPDFRF 270
PIEK+F K+L KF WA++ D ++RF
Sbjct: 728 PIEKLFTKTLRDKFKWAIESADENWRF 754
[206][TOP]
>UniRef100_A5DLX4 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DLX4_PICGU
Length = 754
Score = 75.9 bits (185), Expect = 2e-12
Identities = 36/87 (41%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
Frame = -2
Query: 527 KKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEV 348
K + E L+ ++ + + +I ++ KED + V+LGTSK+NY+DPR+TV + K+ +V
Sbjct: 668 KSTTTVEKLKAQVEKLDGRIVNTTFQLQDKEDNSEVSLGTSKLNYIDPRLTVMFSKKFDV 727
Query: 347 PIEKIFNKSLLAKFTWAMD-VDPDFRF 270
PIEK+F K+L KF WA++ D ++RF
Sbjct: 728 PIEKLFTKTLRDKFKWAIESADENWRF 754
[207][TOP]
>UniRef100_B3GD22 Topoisomerase I (Fragment) n=1 Tax=Chauliognathus opacus
RepID=B3GD22_9COLE
Length = 247
Score = 75.1 bits (183), Expect = 3e-12
Identities = 34/77 (44%), Positives = 52/77 (67%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ E K + + ++ K++ +++ T+ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKTVYEKKRKLLERLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 NDVPIEKIYNKTQRDKF 246
[208][TOP]
>UniRef100_A4R0K7 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4R0K7_MAGGR
Length = 906
Score = 74.7 bits (182), Expect = 4e-12
Identities = 33/77 (42%), Positives = 52/77 (67%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
+ ++ E LE+++ + + +I M+ ++ VALGTSKINY+DPR+TV +C + VP
Sbjct: 819 RGVTVEKLEQQVKKLDERIRTMELQAADRDGNKEVALGTSKINYIDPRLTVVFCNKMNVP 878
Query: 344 IEKIFNKSLLAKFTWAM 294
IEK F+K+L KF WA+
Sbjct: 879 IEKFFSKTLREKFNWAI 895
[209][TOP]
>UniRef100_B3GD37 Topoisomerase I (Fragment) n=1 Tax=Bembidion mandibulare
RepID=B3GD37_9CARA
Length = 247
Score = 74.3 bits (181), Expect = 5e-12
Identities = 37/76 (48%), Positives = 54/76 (71%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
KKKK L +++ + K+E M+ D +++ +ALGTSK+NYLDPRI+VAWCK++
Sbjct: 180 KKKKTL------ERLKEQLMKLEVMETD---RDENKAIALGTSKLNYLDPRISVAWCKKY 230
Query: 353 EVPIEKIFNKSLLAKF 306
+VPIEKI+NK+ KF
Sbjct: 231 DVPIEKIYNKTQRDKF 246
[210][TOP]
>UniRef100_A7EXF7 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EXF7_SCLS1
Length = 911
Score = 73.9 bits (180), Expect = 7e-12
Identities = 36/78 (46%), Positives = 51/78 (65%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K S E E I++ + +I M + +E VALGTSKINY+DPR+TV + ++ +VP
Sbjct: 824 KGSSVEKFEANITKIDERIANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVP 883
Query: 344 IEKIFNKSLLAKFTWAMD 291
IEK F+K+L KF WA+D
Sbjct: 884 IEKFFSKTLREKFAWAID 901
[211][TOP]
>UniRef100_B3GD42 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD42_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[212][TOP]
>UniRef100_B3GD39 Topoisomerase I (Fragment) n=2 Tax=Pseudoperyphus
RepID=B3GD39_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[213][TOP]
>UniRef100_B3GD38 Topoisomerase I (Fragment) n=1 Tax=Bembidion concolor
RepID=B3GD38_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[214][TOP]
>UniRef100_B3GD36 Topoisomerase I (Fragment) n=1 Tax=Bembidion rapidum
RepID=B3GD36_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLVKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[215][TOP]
>UniRef100_B3GD34 Topoisomerase I (Fragment) n=1 Tax=Bembidion umbratum
RepID=B3GD34_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTXRDKF 246
[216][TOP]
>UniRef100_B3GD30 Topoisomerase I (Fragment) n=1 Tax=Metrius contractus
RepID=B3GD30_METCO
Length = 281
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVYDKKKKALERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 264 YDVPIEKIYNKTQRDKF 280
[217][TOP]
>UniRef100_B3GD29 Topoisomerase I (Fragment) n=1 Tax=Scaphinotus petersi
RepID=B3GD29_9CARA
Length = 247
Score = 73.6 bits (179), Expect = 9e-12
Identities = 32/77 (41%), Positives = 54/77 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKTLERLKDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKAQRDKF 246
[218][TOP]
>UniRef100_B3GD43 Topoisomerase I (Fragment) n=1 Tax=Bembidion chalceum
RepID=B3GD43_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 1e-11
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[219][TOP]
>UniRef100_B3GD35 Topoisomerase I (Fragment) n=1 Tax=Bembidion plagiatum
RepID=B3GD35_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 1e-11
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[220][TOP]
>UniRef100_B3GD33 Topoisomerase I (Fragment) n=1 Tax=Bembidion transversale
RepID=B3GD33_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 1e-11
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLERLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRHKF 246
[221][TOP]
>UniRef100_B3GD32 Topoisomerase I (Fragment) n=1 Tax=Asaphidion yukonense
RepID=B3GD32_9CARA
Length = 247
Score = 73.2 bits (178), Expect = 1e-11
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ +ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVYDKKKKMLEKLKEQLIKLEVQETDRDENKAIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPIEKIFNKSLLAKF 306
++VPIEKI+NK+ KF
Sbjct: 230 YDVPIEKIYNKTQRDKF 246
[222][TOP]
>UniRef100_B3GD28 Topoisomerase I (Fragment) n=1 Tax=Calosoma scrutator
RepID=B3GD28_CALSB
Length = 281
Score = 73.2 bits (178), Expect = 1e-11
Identities = 33/77 (42%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ K++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVYDKKKKALEKLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 356 HEVPIEKIFNKSLLAKF 306
+ VPIEKI+NK+ KF
Sbjct: 264 YGVPIEKIYNKTQRDKF 280
[223][TOP]
>UniRef100_B3GD41 Topoisomerase I (Fragment) n=1 Tax=Bembidion inaequale
RepID=B3GD41_9CARA
Length = 247
Score = 72.8 bits (177), Expect = 1e-11
Identities = 36/76 (47%), Positives = 55/76 (72%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
KKKK L +++ + K+E ++ D +++ ++ALGTSK+NYLDPRI+VAWCK++
Sbjct: 180 KKKKML------ERLKEQLIKLEVLETD---RDENKSIALGTSKLNYLDPRISVAWCKKY 230
Query: 353 EVPIEKIFNKSLLAKF 306
+VPIEKI+NK+ KF
Sbjct: 231 DVPIEKIYNKTQRDKF 246
[224][TOP]
>UniRef100_B3GD21 Topoisomerase I (Fragment) n=1 Tax=Prolixocupes lobiceps
RepID=B3GD21_9COLE
Length = 229
Score = 72.8 bits (177), Expect = 1e-11
Identities = 32/77 (41%), Positives = 53/77 (68%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRITVAWCK+
Sbjct: 152 GSVKEKVVYDKKKKHLERLREQLVKLEVAETDRDENKSIALGTSKLNYLDPRITVAWCKK 211
Query: 356 HEVPIEKIFNKSLLAKF 306
+ VPIEK++NK+ KF
Sbjct: 212 YGVPIEKVYNKTQRDKF 228
[225][TOP]
>UniRef100_B2AY06 Predicted CDS Pa_1_9460 n=1 Tax=Podospora anserina RepID=B2AY06_PODAN
Length = 904
Score = 72.8 bits (177), Expect = 1e-11
Identities = 35/78 (44%), Positives = 52/78 (66%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K + E LE +S+ + +I+ ++ +E VALGTSKINY+DPR+TV + K+ VP
Sbjct: 817 KGPAVEKLEAAVSKFDDRIKTLELQCADREGNKEVALGTSKINYIDPRLTVVFAKKFNVP 876
Query: 344 IEKIFNKSLLAKFTWAMD 291
IEK F+K+L KF WA++
Sbjct: 877 IEKFFSKTLRDKFKWAIE 894
[226][TOP]
>UniRef100_A6S3Q9 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6S3Q9_BOTFB
Length = 912
Score = 72.4 bits (176), Expect = 2e-11
Identities = 35/78 (44%), Positives = 51/78 (65%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K S + E I++ + +I M + +E VALGTSKINY+DPR+TV + ++ +VP
Sbjct: 825 KGPSVDKFEANITKIDERIANMLLKREDREGNKEVALGTSKINYIDPRLTVVFSQKFDVP 884
Query: 344 IEKIFNKSLLAKFTWAMD 291
IEK F+K+L KF WA+D
Sbjct: 885 IEKFFSKTLREKFAWAID 902
[227][TOP]
>UniRef100_P41512 DNA topoisomerase 1 n=1 Tax=Xenopus laevis RepID=TOP1_XENLA
Length = 829
Score = 72.4 bits (176), Expect = 2e-11
Identities = 34/73 (46%), Positives = 52/73 (71%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + S+ +K + + ++ K++ +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 733 DEKTKKLVESK--KKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCK 790
Query: 359 RHEVPIEKIFNKS 321
++ VPIEKI+NK+
Sbjct: 791 KYGVPIEKIYNKT 803
[228][TOP]
>UniRef100_UPI00016E5F97 UPI00016E5F97 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E5F97
Length = 790
Score = 72.0 bits (175), Expect = 3e-11
Identities = 34/73 (46%), Positives = 49/73 (67%)
Frame = -2
Query: 539 DGKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCK 360
D K KK + E K + + ++ K+Q +E+ +ALGTSK+NYLDPRI+VAWCK
Sbjct: 717 DDKSKKAV--EVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCK 774
Query: 359 RHEVPIEKIFNKS 321
+ +PIEKI+NK+
Sbjct: 775 KFGIPIEKIYNKT 787
[229][TOP]
>UniRef100_Q70HS8 DNA topoisomerase I subunit B (Fragment) n=1 Tax=Leishmania
panamensis RepID=Q70HS8_9TRYP
Length = 269
Score = 70.9 bits (172), Expect = 6e-11
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + ++ + + ++ K+D V+LGTSKINY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 317 LAKFTWAMDVD 285
L KF WAM+ +
Sbjct: 255 LKKFPWAMNAE 265
[230][TOP]
>UniRef100_Q4YYG2 Topoisomerase I, putative (Fragment) n=1 Tax=Plasmodium berghei
RepID=Q4YYG2_PLABE
Length = 805
Score = 70.9 bits (172), Expect = 6e-11
Identities = 31/62 (50%), Positives = 46/62 (74%)
Frame = -2
Query: 533 KKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRH 354
K K+N+ E+ +KK+ K+E ++ MK ++D T+ALGTSKINY+DPRITVA+CK+
Sbjct: 744 KVKENMKEESCKKKLIALIKKVELLENQMKVRDDNKTIALGTSKINYMDPRITVAFCKQF 803
Query: 353 EV 348
E+
Sbjct: 804 EI 805
[231][TOP]
>UniRef100_Q7S0F7 DNA topoisomerase I n=1 Tax=Neurospora crassa RepID=Q7S0F7_NEUCR
Length = 874
Score = 70.9 bits (172), Expect = 6e-11
Identities = 34/78 (43%), Positives = 50/78 (64%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K S E LE + + + +I+ ++ +E VALGTSKINY+DPR+TV + + VP
Sbjct: 787 KGPSVEKLEAALEKLDQRIKNLELQSADREGNKEVALGTSKINYIDPRLTVVFSAKFNVP 846
Query: 344 IEKIFNKSLLAKFTWAMD 291
IEK F+K+L KF WA++
Sbjct: 847 IEKFFSKTLREKFKWAIE 864
[232][TOP]
>UniRef100_Q38EP5 DNA topoisomerase type IB small subunit n=1 Tax=Trypanosoma brucei
RepID=Q38EP5_9TRYP
Length = 273
Score = 70.5 bits (171), Expect = 7e-11
Identities = 31/78 (39%), Positives = 51/78 (65%)
Frame = -2
Query: 503 LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 324
+E +I + +++ ++ +K K+D TV+LGTSK+NY+DPRI +W + VPI ++F+
Sbjct: 197 IEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSA 256
Query: 323 SLLAKFTWAMDVDPDFRF 270
+L KF WA+ DF F
Sbjct: 257 TLQKKFPWALKA-RDFTF 273
[233][TOP]
>UniRef100_C9ZXZ7 DNA topoisomerase type IB small subunit, putative n=2
Tax=Trypanosoma brucei RepID=C9ZXZ7_TRYBG
Length = 273
Score = 70.5 bits (171), Expect = 7e-11
Identities = 31/78 (39%), Positives = 51/78 (65%)
Frame = -2
Query: 503 LEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 324
+E +I + +++ ++ +K K+D TV+LGTSK+NY+DPRI +W + VPI ++F+
Sbjct: 197 IEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSA 256
Query: 323 SLLAKFTWAMDVDPDFRF 270
+L KF WA+ DF F
Sbjct: 257 TLQKKFPWALKA-RDFTF 273
[234][TOP]
>UniRef100_A4H3S7 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania
braziliensis RepID=A4H3S7_LEIBR
Length = 269
Score = 70.5 bits (171), Expect = 7e-11
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + ++ + + ++ K+D V+LGTSKINY+DPRI +W K +VPI K+F+ ++
Sbjct: 195 KALVRYRERLNREENVIRIKDDNKAVSLGTSKINYIDPRIVCSWAKAQDVPISKVFSATI 254
Query: 317 LAKFTWAMDVD 285
L KF WAM +
Sbjct: 255 LKKFPWAMSAE 265
[235][TOP]
>UniRef100_Q95Z89 Possible DNA topoisomerase I-related protein n=1 Tax=Leishmania
major RepID=Q95Z89_LEIMA
Length = 262
Score = 69.3 bits (168), Expect = 2e-10
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + ++ + + ++ K+D V+LGTSKINY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 317 LAKFTWAMDVD 285
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[236][TOP]
>UniRef100_Q8WQM6 DNA topoisomerase I-like protein n=1 Tax=Leishmania donovani
RepID=Q8WQM6_LEIDO
Length = 262
Score = 69.3 bits (168), Expect = 2e-10
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + ++ + + ++ K+D V+LGTSKINY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 317 LAKFTWAMDVD 285
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[237][TOP]
>UniRef100_A4HS02 DNA topoisomerase type IB small subunit n=1 Tax=Leishmania infantum
RepID=A4HS02_LEIIN
Length = 262
Score = 69.3 bits (168), Expect = 2e-10
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + ++ + + ++ K+D V+LGTSKINY+DPRI +W K +VPI KIF+ ++
Sbjct: 188 KALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATI 247
Query: 317 LAKFTWAMDVD 285
KF WAM+ +
Sbjct: 248 QKKFPWAMNAE 258
[238][TOP]
>UniRef100_Q2HDT9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2HDT9_CHAGB
Length = 907
Score = 68.9 bits (167), Expect = 2e-10
Identities = 33/77 (42%), Positives = 48/77 (62%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
K S E L + + + +I ++ +E VALGTSKINY+DPR+TV + + +VP
Sbjct: 820 KGPSVEKLTTAVEKLDERIRTLEMQSADREGNKEVALGTSKINYIDPRLTVVFSNKFQVP 879
Query: 344 IEKIFNKSLLAKFTWAM 294
IEK F+K+L KF WA+
Sbjct: 880 IEKFFSKTLRDKFNWAI 896
[239][TOP]
>UniRef100_C7YQG7 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YQG7_NECH7
Length = 919
Score = 68.2 bits (165), Expect = 4e-10
Identities = 30/68 (44%), Positives = 48/68 (70%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K I + + +++ ++ + ++ VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L
Sbjct: 841 KAIEKLDERVKVLETQAEDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTL 900
Query: 317 LAKFTWAM 294
KF WA+
Sbjct: 901 RDKFRWAI 908
[240][TOP]
>UniRef100_UPI000023DEFB hypothetical protein FG06874.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DEFB
Length = 910
Score = 67.8 bits (164), Expect = 5e-10
Identities = 30/68 (44%), Positives = 48/68 (70%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + + +I+ ++ + ++ VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L
Sbjct: 832 KAVDKFDERIKTLELQAQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTL 891
Query: 317 LAKFTWAM 294
KF WA+
Sbjct: 892 RDKFRWAI 899
[241][TOP]
>UniRef100_C4PFJ5 Topoisomerase I n=1 Tax=Fusarium culmorum RepID=C4PFJ5_FUSCU
Length = 909
Score = 67.8 bits (164), Expect = 5e-10
Identities = 30/68 (44%), Positives = 48/68 (70%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
K + + + +I+ ++ + ++ VALGTSKINY+DPR+TV + K+ +VPIEK F+K+L
Sbjct: 831 KAVDKFDERIKTLELQAQDRDGNKEVALGTSKINYIDPRLTVVFSKKFDVPIEKFFSKTL 890
Query: 317 LAKFTWAM 294
KF WA+
Sbjct: 891 RDKFRWAI 898
[242][TOP]
>UniRef100_Q5RL92 Type IB topoisomerase small subunit n=1 Tax=Trypanosoma cruzi
RepID=Q5RL92_TRYCR
Length = 271
Score = 67.4 bits (163), Expect = 6e-10
Identities = 28/63 (44%), Positives = 43/63 (68%)
Frame = -2
Query: 473 KIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 294
++ + + ++ K+D V+LGTSK+NY+DPRI +W K + VPI KIF+ +L KF WAM
Sbjct: 205 RLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWAM 264
Query: 293 DVD 285
+
Sbjct: 265 GAE 267
[243][TOP]
>UniRef100_Q4DUD0 DNA topoisomerase type IB small subunit, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DUD0_TRYCR
Length = 272
Score = 67.4 bits (163), Expect = 6e-10
Identities = 28/63 (44%), Positives = 43/63 (68%)
Frame = -2
Query: 473 KIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAM 294
++ + + ++ K+D V+LGTSK+NY+DPRI +W K + VPI KIF+ +L KF WAM
Sbjct: 206 RLNREENMIRIKDDNKAVSLGTSKVNYIDPRIVCSWAKEYNVPIGKIFSATLQKKFPWAM 265
Query: 293 DVD 285
+
Sbjct: 266 GAE 268
[244][TOP]
>UniRef100_A9V5T5 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V5T5_MONBE
Length = 2575
Score = 65.5 bits (158), Expect = 2e-09
Identities = 27/58 (46%), Positives = 41/58 (70%)
Frame = -2
Query: 509 EALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEK 336
+ L++K+ + ++ K Q KE+ +AL TSK+NYLDPRI+VAWCK H+VP++K
Sbjct: 2334 DVLKRKVDRLEERLHKKQIAKVDKEENKCIALSTSKLNYLDPRISVAWCKTHDVPVDK 2391
[245][TOP]
>UniRef100_C9SIQ6 DNA topoisomerase n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SIQ6_9PEZI
Length = 891
Score = 65.5 bits (158), Expect = 2e-09
Identities = 33/74 (44%), Positives = 49/74 (66%), Gaps = 1/74 (1%)
Frame = -2
Query: 497 KKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 318
KKI + +E +D ++ VALGTSK+NY+DPR+TV + ++ +VPIEK F+K++
Sbjct: 817 KKIEERAKNLELQAQDRDGNKE---VALGTSKLNYIDPRLTVVFSRKFDVPIEKFFSKTM 873
Query: 317 LAKFTWAM-DVDPD 279
KF WA+ VD D
Sbjct: 874 REKFNWAIQSVDDD 887
[246][TOP]
>UniRef100_C3ZV88 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
floridae RepID=C3ZV88_BRAFL
Length = 299
Score = 62.4 bits (150), Expect = 2e-08
Identities = 31/77 (40%), Positives = 49/77 (63%)
Frame = -2
Query: 524 KNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKRHEVP 345
+ + E +K++ + ++ K++ KE+ +ALGTSK+NYLDPRI+VA K H
Sbjct: 226 RQMMLERKKKQMERLEEQLMKLEVQATDKEENKEIALGTSKLNYLDPRISVACGKSH--- 282
Query: 344 IEKIFNKSLLAKFTWAM 294
+EKI+NK+ KF WA+
Sbjct: 283 VEKIYNKTQRDKFAWAL 299
[247][TOP]
>UniRef100_B3GD25 Topoisomerase I (Fragment) n=1 Tax=Amphizoa lecontei
RepID=B3GD25_AMPLE
Length = 268
Score = 62.4 bits (150), Expect = 2e-08
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ K++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 204 GSVKEKVVLDKKKKGLERLKDQLVKLEVQETDKDENKSIALGTSKLNYLDPRISVAWCKK 263
Query: 356 HEVPI 342
+EVPI
Sbjct: 264 YEVPI 268
[248][TOP]
>UniRef100_B3GD24 Topoisomerase I (Fragment) n=1 Tax=Copelatus distinctus
RepID=B3GD24_9DYTI
Length = 234
Score = 62.0 bits (149), Expect = 3e-08
Identities = 25/65 (38%), Positives = 46/65 (70%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + +++K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVHDKKKKALERLKDQLKKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPI 342
++VPI
Sbjct: 230 YDVPI 234
[249][TOP]
>UniRef100_B3GD26 Topoisomerase I (Fragment) n=1 Tax=Dineutes sublineatus
RepID=B3GD26_9COLE
Length = 234
Score = 61.2 bits (147), Expect = 4e-08
Identities = 24/65 (36%), Positives = 47/65 (72%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + ++ +K++ + ++ +++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKERVVADKKKKQLDRLRDQLVRLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPI 342
++VPI
Sbjct: 230 YDVPI 234
[250][TOP]
>UniRef100_B3GD20 Topoisomerase I (Fragment) n=1 Tax=Sialis sp. ALW-2008
RepID=B3GD20_9NEOP
Length = 234
Score = 60.8 bits (146), Expect = 6e-08
Identities = 25/65 (38%), Positives = 45/65 (69%)
Frame = -2
Query: 536 GKKKKNLSSEALEKKISQTNAKIEKMQRDMKTKEDLNTVALGTSKINYLDPRITVAWCKR 357
G K+ + + +K + + ++ K++ +++ ++ALGTSK+NYLDPRI+VAWCK+
Sbjct: 170 GSVKEKVVHDKKKKALERLRDQLMKLEVQETDRDENKSIALGTSKLNYLDPRISVAWCKK 229
Query: 356 HEVPI 342
++VPI
Sbjct: 230 YDVPI 234