[UP]
[1][TOP]
>UniRef100_B9H5I2 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9H5I2_POPTR
Length = 1274
Score = 133 bits (335), Expect = 6e-30
Identities = 65/77 (84%), Positives = 73/77 (94%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FSRTEVFV+YYFQMYL+LVLLGFLHGLVFLPVVLS+FGP
Sbjct: 1195 MGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMFGP 1254
Query: 327 PSRCTIIEQEENRSSTS 277
PSRC ++E++E+R S S
Sbjct: 1255 PSRCKLVEKQEDRLSVS 1271
[2][TOP]
>UniRef100_B9R8N7 Hedgehog receptor, putative n=1 Tax=Ricinus communis
RepID=B9R8N7_RICCO
Length = 1235
Score = 132 bits (331), Expect = 2e-29
Identities = 64/77 (83%), Positives = 72/77 (93%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGV+VL FSRTEVFV+YYFQMYL+LVLLGFLHGLVFLPVVLS+FGP
Sbjct: 1156 MGASVFSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMFGP 1215
Query: 327 PSRCTIIEQEENRSSTS 277
PSRC ++E+ E+R S S
Sbjct: 1216 PSRCKLVEKPEDRPSVS 1232
[3][TOP]
>UniRef100_UPI0001985140 PREDICTED: similar to patched family protein n=1 Tax=Vitis vinifera
RepID=UPI0001985140
Length = 1018
Score = 129 bits (324), Expect = 1e-28
Identities = 64/78 (82%), Positives = 72/78 (92%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FSRTEVFV+YYFQMYL+LVLLGFLHGLVFLPVVLS+ GP
Sbjct: 939 MGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMCGP 998
Query: 327 PSRCTIIEQEENRSSTSS 274
PSRC +I++ E++ S SS
Sbjct: 999 PSRCVLIDKREDQPSPSS 1016
[4][TOP]
>UniRef100_A7QPC0 Chromosome chr18 scaffold_137, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QPC0_VITVI
Length = 1263
Score = 129 bits (324), Expect = 1e-28
Identities = 64/78 (82%), Positives = 72/78 (92%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FSRTEVFV+YYFQMYL+LVLLGFLHGLVFLPVVLS+ GP
Sbjct: 1184 MGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMCGP 1243
Query: 327 PSRCTIIEQEENRSSTSS 274
PSRC +I++ E++ S SS
Sbjct: 1244 PSRCVLIDKREDQPSPSS 1261
[5][TOP]
>UniRef100_B9SMD3 Putative uncharacterized protein n=1 Tax=Ricinus communis
RepID=B9SMD3_RICCO
Length = 584
Score = 120 bits (300), Expect = 7e-26
Identities = 58/78 (74%), Positives = 69/78 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL+FSR+E+FV+YYFQMYL+LVL+GFLHGLVFLPV+LS+FGP
Sbjct: 505 MGASVFSGITLTKLVGVIVLFFSRSEIFVVYYFQMYLALVLIGFLHGLVFLPVILSMFGP 564
Query: 327 PSRCTIIEQEENRSSTSS 274
P+R I E S +S+
Sbjct: 565 PARHVIKNPEAEPSGSSN 582
[6][TOP]
>UniRef100_UPI0001982F17 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI0001982F17
Length = 1345
Score = 118 bits (295), Expect = 3e-25
Identities = 57/78 (73%), Positives = 70/78 (89%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FS++E+FV+YYFQMYL+LVL+GFLHGLVFLPV+LS+ GP
Sbjct: 1265 MGASVFSGITLTKLVGVIVLCFSKSEIFVVYYFQMYLALVLIGFLHGLVFLPVILSMIGP 1324
Query: 327 PSRCTIIEQEENRSSTSS 274
PS I+Q+E+ S+S+
Sbjct: 1325 PSMHVPIKQQEDEPSSSA 1342
[7][TOP]
>UniRef100_B9HPX9 Cholesterol transport protein n=1 Tax=Populus trichocarpa
RepID=B9HPX9_POPTR
Length = 1223
Score = 118 bits (295), Expect = 3e-25
Identities = 56/68 (82%), Positives = 65/68 (95%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL+F+R+EVFV+YYFQMYL+LV++GFLHGLVFLPVVLS+FGP
Sbjct: 1154 MGASVFSGITLTKLVGVIVLFFARSEVFVVYYFQMYLALVIIGFLHGLVFLPVVLSVFGP 1213
Query: 327 PSRCTIIE 304
P R I+E
Sbjct: 1214 PPRHVIME 1221
[8][TOP]
>UniRef100_A7P8Q4 Chromosome chr3 scaffold_8, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7P8Q4_VITVI
Length = 1217
Score = 118 bits (295), Expect = 3e-25
Identities = 57/78 (73%), Positives = 70/78 (89%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FS++E+FV+YYFQMYL+LVL+GFLHGLVFLPV+LS+ GP
Sbjct: 1137 MGASVFSGITLTKLVGVIVLCFSKSEIFVVYYFQMYLALVLIGFLHGLVFLPVILSMIGP 1196
Query: 327 PSRCTIIEQEENRSSTSS 274
PS I+Q+E+ S+S+
Sbjct: 1197 PSMHVPIKQQEDEPSSSA 1214
[9][TOP]
>UniRef100_Q9C8F0 Putative uncharacterized protein T8D8.3 (Fragment) n=1
Tax=Arabidopsis thaliana RepID=Q9C8F0_ARATH
Length = 524
Score = 115 bits (287), Expect = 2e-24
Identities = 59/78 (75%), Positives = 68/78 (87%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL FSR+EVFV+YYF+MYL+LVLLGFLHGLVFLPV LS+FGP
Sbjct: 445 MGASVFSGITLTKLVGVIVLGFSRSEVFVVYYFKMYLALVLLGFLHGLVFLPVFLSMFGP 504
Query: 327 PSRCTIIEQEENRSSTSS 274
R E++++R S SS
Sbjct: 505 APRHVEGERQDHRPSVSS 522
[10][TOP]
>UniRef100_UPI0001A7B126 hedgehog receptor n=1 Tax=Arabidopsis thaliana RepID=UPI0001A7B126
Length = 1234
Score = 114 bits (285), Expect = 4e-24
Identities = 55/78 (70%), Positives = 68/78 (87%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL F+R+E+FV+YYFQMYL+LV++GFLHGLVFLPV+LS+ GP
Sbjct: 1154 MGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLAGP 1213
Query: 327 PSRCTIIEQEENRSSTSS 274
P IEQ++ ++SS
Sbjct: 1214 PQLNLDIEQQQTDEASSS 1231
[11][TOP]
>UniRef100_Q9SVF0 Putative uncharacterized protein AT4g38350 n=1 Tax=Arabidopsis
thaliana RepID=Q9SVF0_ARATH
Length = 1055
Score = 114 bits (285), Expect = 4e-24
Identities = 55/78 (70%), Positives = 68/78 (87%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL F+R+E+FV+YYFQMYL+LV++GFLHGLVFLPV+LS+ GP
Sbjct: 975 MGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLAGP 1034
Query: 327 PSRCTIIEQEENRSSTSS 274
P IEQ++ ++SS
Sbjct: 1035 PQLNLDIEQQQTDEASSS 1052
[12][TOP]
>UniRef100_A5BXT3 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BXT3_VITVI
Length = 692
Score = 109 bits (273), Expect = 9e-23
Identities = 57/89 (64%), Positives = 70/89 (78%), Gaps = 11/89 (12%)
Frame = -1
Query: 507 MGASVF-----------SGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLV 361
MGASVF SGITLTKLVGVIVL FS++E+FV+YYFQMYL+LVL+GFLHGLV
Sbjct: 601 MGASVFRCLYFDFDFFFSGITLTKLVGVIVLCFSKSEIFVVYYFQMYLALVLIGFLHGLV 660
Query: 360 FLPVVLSIFGPPSRCTIIEQEENRSSTSS 274
FLPV+LS+ GPPS I+Q+E+ S+S+
Sbjct: 661 FLPVILSMIGPPSMHVPIKQQEDEPSSSA 689
[13][TOP]
>UniRef100_A0SPW2 At1g42470-like protein (Fragment) n=1 Tax=Arabidopsis halleri
subsp. halleri RepID=A0SPW2_ARAHA
Length = 98
Score = 107 bits (267), Expect = 5e-22
Identities = 53/63 (84%), Positives = 59/63 (93%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+GASVFSGITLTKLVGVIVL FSR+EVFV+YYF+MYL+LVLLGFLHGLVFLPV LS+FGP
Sbjct: 35 IGASVFSGITLTKLVGVIVLSFSRSEVFVVYYFKMYLALVLLGFLHGLVFLPVFLSMFGP 94
Query: 327 PSR 319
R
Sbjct: 95 SPR 97
[14][TOP]
>UniRef100_A0SPY7 At1g42470-like protein (Fragment) n=4 Tax=Arabidopsis lyrata
RepID=A0SPY7_ARALP
Length = 98
Score = 102 bits (254), Expect = 1e-20
Identities = 51/58 (87%), Positives = 56/58 (96%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIF 334
MGASVFSGITLTKLVGVIVL FSR+EVFV+YYF+MYL+LVLLGFLHGLVFLPV LS+F
Sbjct: 35 MGASVFSGITLTKLVGVIVLGFSRSEVFVVYYFKMYLALVLLGFLHGLVFLPVFLSMF 92
[15][TOP]
>UniRef100_Q9SHN9 F7F22.1 n=1 Tax=Arabidopsis thaliana RepID=Q9SHN9_ARATH
Length = 1275
Score = 97.1 bits (240), Expect = 6e-19
Identities = 48/53 (90%), Positives = 52/53 (98%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPV 349
MGASVFSGITLTKLVGVIVL FSR+EVFV+YYF+MYL+LVLLGFLHGLVFLPV
Sbjct: 1180 MGASVFSGITLTKLVGVIVLGFSRSEVFVVYYFKMYLALVLLGFLHGLVFLPV 1232
[16][TOP]
>UniRef100_Q7XUB7 OSJNBb0078D11.11 protein n=1 Tax=Oryza sativa Japonica Group
RepID=Q7XUB7_ORYSJ
Length = 1361
Score = 95.9 bits (237), Expect = 1e-18
Identities = 45/62 (72%), Positives = 55/62 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL F+++EVFV+YYFQMYL+LV++GFLHGL+FLP ++
Sbjct: 1212 MGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLHGLIFLPCYIATSSH 1271
Query: 327 PS 322
PS
Sbjct: 1272 PS 1273
[17][TOP]
>UniRef100_Q01KH5 H0409D10.4 protein n=1 Tax=Oryza sativa RepID=Q01KH5_ORYSA
Length = 1372
Score = 95.9 bits (237), Expect = 1e-18
Identities = 45/62 (72%), Positives = 55/62 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MGASVFSGITLTKLVGVIVL F+++EVFV+YYFQMYL+LV++GFLHGL+FLP ++
Sbjct: 1212 MGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLHGLIFLPCYIATSSH 1271
Query: 327 PS 322
PS
Sbjct: 1272 PS 1273
[18][TOP]
>UniRef100_C5YE00 Putative uncharacterized protein Sb06g025390 n=1 Tax=Sorghum bicolor
RepID=C5YE00_SORBI
Length = 1232
Score = 94.7 bits (234), Expect = 3e-18
Identities = 44/53 (83%), Positives = 52/53 (98%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPV 349
MGASVFSGITLTKLVGVIVL F+++EVFV+YYFQMYL+LV++GFLHGL+FLPV
Sbjct: 1178 MGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLHGLIFLPV 1230
[19][TOP]
>UniRef100_C3ZSN0 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3ZSN0_BRAFL
Length = 1368
Score = 88.6 bits (218), Expect = 2e-16
Identities = 39/60 (65%), Positives = 53/60 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F ++YF+MYLS+VLLGF HGL+FLPV+LS GP
Sbjct: 1260 MGSSVFSGITLTKFGGIVVLAFAKSQLFQVFYFRMYLSIVLLGFSHGLIFLPVLLSYIGP 1319
[20][TOP]
>UniRef100_Q9TVK6 Niemann-Pick C type protein n=1 Tax=Dictyostelium discoideum
RepID=Q9TVK6_DICDI
Length = 1342
Score = 88.2 bits (217), Expect = 3e-16
Identities = 40/59 (67%), Positives = 52/59 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG+S+ SGI +TKL+GV+VL FS +E+F +YYF+MYLS+V LG LHGLVFLPV+LS+FG
Sbjct: 1262 MGSSIISGIFITKLLGVVVLGFSTSEIFTVYYFRMYLSIVFLGGLHGLVFLPVLLSLFG 1320
[21][TOP]
>UniRef100_A9RFW8 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
patens RepID=A9RFW8_PHYPA
Length = 1262
Score = 87.8 bits (216), Expect = 4e-16
Identities = 41/60 (68%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG VFSGITLTK+VGV+VL F+++++F +YYF+MYL LV+LG LHGLVFLPV LS+ GP
Sbjct: 1169 MGEPVFSGITLTKMVGVLVLNFAQSKIFKVYYFRMYLGLVVLGALHGLVFLPVWLSVAGP 1228
[22][TOP]
>UniRef100_UPI000194BC77 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Taeniopygia guttata
RepID=UPI000194BC77
Length = 1280
Score = 87.0 bits (214), Expect = 6e-16
Identities = 39/60 (65%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL FS++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1196 MGSSVFSGITLTKFGGIVVLAFSKSQIFKIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1255
[23][TOP]
>UniRef100_UPI00015B5F3E PREDICTED: similar to CG5722-PA n=1 Tax=Nasonia vitripennis
RepID=UPI00015B5F3E
Length = 1253
Score = 87.0 bits (214), Expect = 6e-16
Identities = 38/60 (63%), Positives = 51/60 (85%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVFSGITLTK VG+ VL F++T++F ++YF+MYL +VLLG HGL+FLPV+LS GP
Sbjct: 1188 VGSSVFSGITLTKFVGIAVLGFAKTQIFTVFYFRMYLGIVLLGAAHGLIFLPVLLSFIGP 1247
[24][TOP]
>UniRef100_UPI0000E7FEDB PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Gallus gallus
RepID=UPI0000E7FEDB
Length = 1261
Score = 87.0 bits (214), Expect = 6e-16
Identities = 39/60 (65%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL FS++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1177 MGSSVFSGITLTKFGGIVVLAFSKSQIFKIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1236
[25][TOP]
>UniRef100_UPI000060FC24 Niemann-Pick C1 protein precursor. n=1 Tax=Gallus gallus
RepID=UPI000060FC24
Length = 1278
Score = 87.0 bits (214), Expect = 6e-16
Identities = 39/60 (65%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL FS++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1194 MGSSVFSGITLTKFGGIVVLAFSKSQIFKIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253
[26][TOP]
>UniRef100_UPI00017966B6 PREDICTED: similar to Niemann-Pick C1 n=1 Tax=Equus caballus
RepID=UPI00017966B6
Length = 1293
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/85 (50%), Positives = 60/85 (70%), Gaps = 2/85 (2%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1209 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1268
Query: 327 P--SRCTIIEQEENRSSTSS*LYTF 259
T+ QE + + L F
Sbjct: 1269 SINKAKTLATQERYKGTEREQLLNF 1293
[27][TOP]
>UniRef100_UPI0000F2C55D PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2C55D
Length = 1280
Score = 86.3 bits (212), Expect = 1e-15
Identities = 44/85 (51%), Positives = 59/85 (69%), Gaps = 2/85 (2%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+ VFSGITLTK G++VL F+R+++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1196 MGSCVFSGITLTKFGGIVVLAFARSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1255
Query: 327 P--SRCTIIEQEENRSSTSS*LYTF 259
+ QE NR + L F
Sbjct: 1256 SVNKAKSHAAQERNRGTERERLLNF 1280
[28][TOP]
>UniRef100_UPI000069EB67 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB67
Length = 1283
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/85 (50%), Positives = 59/85 (69%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK VG+ VL S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1199 MGSSVFSGITLTKFVGIGVLGLSKSQIFKIFYFRMYLAMVLLGAAHGLIFLPVLLSYLGP 1258
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNH 253
++ R+ + FNH
Sbjct: 1259 QVNKAKVQAALQRARGTEQERLFNH 1283
[29][TOP]
>UniRef100_UPI000069EB66 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB66
Length = 1289
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/85 (50%), Positives = 59/85 (69%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK VG+ VL S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1205 MGSSVFSGITLTKFVGIGVLGLSKSQIFKIFYFRMYLAMVLLGAAHGLIFLPVLLSYLGP 1264
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNH 253
++ R+ + FNH
Sbjct: 1265 QVNKAKVQAALQRARGTEQERLFNH 1289
[30][TOP]
>UniRef100_UPI000069EB65 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB65
Length = 1282
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/85 (50%), Positives = 59/85 (69%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK VG+ VL S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1198 MGSSVFSGITLTKFVGIGVLGLSKSQIFKIFYFRMYLAMVLLGAAHGLIFLPVLLSYLGP 1257
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNH 253
++ R+ + FNH
Sbjct: 1258 QVNKAKVQAALQRARGTEQERLFNH 1282
[31][TOP]
>UniRef100_UPI000069EB64 Niemann-Pick C1 protein precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069EB64
Length = 1280
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/85 (50%), Positives = 59/85 (69%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK VG+ VL S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1196 MGSSVFSGITLTKFVGIGVLGLSKSQIFKIFYFRMYLAMVLLGAAHGLIFLPVLLSYLGP 1255
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNH 253
++ R+ + FNH
Sbjct: 1256 QVNKAKVQAALQRARGTEQERLFNH 1280
[32][TOP]
>UniRef100_B0JYK2 NPC1 protein n=2 Tax=Bos taurus RepID=B0JYK2_BOVIN
Length = 1277
Score = 86.3 bits (212), Expect = 1e-15
Identities = 39/60 (65%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+IVL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIIVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[33][TOP]
>UniRef100_Q9GLC9 Niemann-Pick type C1 disease protein n=1 Tax=Bos taurus
RepID=Q9GLC9_BOVIN
Length = 1277
Score = 86.3 bits (212), Expect = 1e-15
Identities = 39/60 (65%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+IVL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIIVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[34][TOP]
>UniRef100_UPI000036A3B7 PREDICTED: Niemann-Pick disease, type C1 isoform 4 n=2 Tax=Pan
troglodytes RepID=UPI000036A3B7
Length = 1277
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[35][TOP]
>UniRef100_UPI00001830DD Cdig2 protein n=1 Tax=Rattus norvegicus RepID=UPI00001830DD
Length = 1278
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1194 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253
[36][TOP]
>UniRef100_UPI00005638CC Niemann Pick type C1 n=1 Tax=Mus musculus RepID=UPI00005638CC
Length = 1277
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[37][TOP]
>UniRef100_Q7TMD4 Niemann Pick type C1 n=1 Tax=Mus musculus RepID=Q7TMD4_MOUSE
Length = 1277
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[38][TOP]
>UniRef100_B2RYH4 Cdig2 protein (Fragment) n=1 Tax=Rattus norvegicus RepID=B2RYH4_RAT
Length = 322
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 238 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 297
[39][TOP]
>UniRef100_Q9TT75 Niemann-Pick type C1 disease protein n=1 Tax=Oryctolagus cuniculus
RepID=Q9TT75_RABIT
Length = 1286
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1202 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1261
[40][TOP]
>UniRef100_Q9N0Q0 Niemann-Pick type C1 disease protein n=1 Tax=Felis catus
RepID=Q9N0Q0_FELCA
Length = 1276
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1192 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1251
[41][TOP]
>UniRef100_Q8MKD8 Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MKD8_FELCA
Length = 1276
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1192 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1251
[42][TOP]
>UniRef100_Q8MI49 Mutant Niemann-Pick C1 n=1 Tax=Felis catus RepID=Q8MI49_FELCA
Length = 1276
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1192 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1251
[43][TOP]
>UniRef100_Q551C5 Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum
RepID=Q551C5_DICDI
Length = 1397
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/59 (64%), Positives = 52/59 (88%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MGA++FSGI +TKL+G +VL FS++E+F+IYYF+MY+S+ LL +HGLV LPV+LSIFG
Sbjct: 1323 MGANIFSGIFITKLLGCVVLAFSKSEIFIIYYFKMYISICLLAAVHGLVLLPVLLSIFG 1381
[44][TOP]
>UniRef100_Q59GR1 Niemann-Pick disease, type C1 variant (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GR1_HUMAN
Length = 1289
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1205 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1264
[45][TOP]
>UniRef100_B4DET3 cDNA FLJ51802, highly similar to Niemann-Pick C1 protein n=1 Tax=Homo
sapiens RepID=B4DET3_HUMAN
Length = 960
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 876 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 935
[46][TOP]
>UniRef100_P56941 Niemann-Pick C1 protein n=1 Tax=Sus scrofa RepID=NPC1_PIG
Length = 1277
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVLLGATHGLIFLPVLLSYIGP 1252
[47][TOP]
>UniRef100_O35604 Niemann-Pick C1 protein n=1 Tax=Mus musculus RepID=NPC1_MOUSE
Length = 1278
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1194 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253
[48][TOP]
>UniRef100_O15118 Niemann-Pick C1 protein n=1 Tax=Homo sapiens RepID=NPC1_HUMAN
Length = 1278
Score = 85.9 bits (211), Expect = 1e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1194 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253
[49][TOP]
>UniRef100_UPI0000586B35 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000586B35
Length = 1332
Score = 85.5 bits (210), Expect = 2e-15
Identities = 39/72 (54%), Positives = 57/72 (79%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVFSGITLTK G+I+L FS +++F +YYF+MYL +V+ G HGL+FLPV+LS GP
Sbjct: 1235 VGSSVFSGITLTKAFGIIILAFSHSQLFKVYYFRMYLGMVVFGATHGLIFLPVLLSYIGP 1294
Query: 327 -PSRCTIIEQEE 295
++ I+E++E
Sbjct: 1295 GVNKARILEEQE 1306
[50][TOP]
>UniRef100_UPI0000EB3851 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3851
Length = 1285
Score = 85.5 bits (210), Expect = 2e-15
Identities = 37/60 (61%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F ++YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1201 MGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1260
[51][TOP]
>UniRef100_UPI0000EB3850 Niemann-Pick type C1 disease protein. n=1 Tax=Canis lupus familiaris
RepID=UPI0000EB3850
Length = 1277
Score = 85.5 bits (210), Expect = 2e-15
Identities = 37/60 (61%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F ++YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1252
[52][TOP]
>UniRef100_Q9JLG3 Niemann-Pick type C1 protein n=1 Tax=Cricetulus griseus
RepID=Q9JLG3_CRIGR
Length = 1277
Score = 85.5 bits (210), Expect = 2e-15
Identities = 38/60 (63%), Positives = 52/60 (86%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAIVLLGATHGLIFLPVLLSYVGP 1252
[53][TOP]
>UniRef100_UPI0001924FA4 PREDICTED: similar to predicted protein n=1 Tax=Hydra magnipapillata
RepID=UPI0001924FA4
Length = 920
Score = 85.1 bits (209), Expect = 2e-15
Identities = 35/63 (55%), Positives = 53/63 (84%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SV SGIT+TK +GV VL F+++++F +YYF+MY+ ++L+G +HGLVFLPV+LS GP
Sbjct: 820 VGSSVLSGITVTKSIGVFVLLFAKSQMFEVYYFRMYMGVILIGAIHGLVFLPVLLSFIGP 879
Query: 327 PSR 319
P +
Sbjct: 880 PQK 882
[54][TOP]
>UniRef100_UPI0000E24CB5 PREDICTED: Niemann-Pick disease, type C1 isoform 2 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB5
Length = 1261
Score = 84.7 bits (208), Expect = 3e-15
Identities = 39/69 (56%), Positives = 54/69 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS G
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGK 1252
Query: 327 PSRCTIIEQ 301
S + Q
Sbjct: 1253 SSHLKRVAQ 1261
[55][TOP]
>UniRef100_UPI00017B0961 UPI00017B0961 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B0961
Length = 1266
Score = 84.0 bits (206), Expect = 5e-15
Identities = 37/60 (61%), Positives = 51/60 (85%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+++L S++++F ++YF+MYL++VLLG HGLVFLPV+LS GP
Sbjct: 1182 MGSSVFSGITLTKFGGILILALSKSQIFQVFYFRMYLAIVLLGAAHGLVFLPVLLSYIGP 1241
[56][TOP]
>UniRef100_UPI000186EA3E Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186EA3E
Length = 1278
Score = 83.6 bits (205), Expect = 7e-15
Identities = 37/60 (61%), Positives = 50/60 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+IVL F+++++F ++YF+MYL +VL G HGL+FLPV+LS GP
Sbjct: 1178 MGSSVFSGITLTKFGGIIVLGFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSYIGP 1237
[57][TOP]
>UniRef100_UPI00016E624E UPI00016E624E related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E624E
Length = 1264
Score = 83.6 bits (205), Expect = 7e-15
Identities = 36/60 (60%), Positives = 51/60 (85%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+++L S++++F ++YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1180 MGSSVFSGITLTKFGGILILALSKSQIFQVFYFRMYLAIVLLGAAHGLIFLPVLLSYIGP 1239
[58][TOP]
>UniRef100_Q9VRC9 NPC1b n=1 Tax=Drosophila melanogaster RepID=Q9VRC9_DROME
Length = 1254
Score = 83.6 bits (205), Expect = 7e-15
Identities = 35/62 (56%), Positives = 50/62 (80%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GPP
Sbjct: 1175 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGPP 1234
Query: 324 SR 319
+
Sbjct: 1235 QK 1236
[59][TOP]
>UniRef100_Q7PS03 AGAP000579-PA (Fragment) n=1 Tax=Anopheles gambiae RepID=Q7PS03_ANOGA
Length = 1247
Score = 83.6 bits (205), Expect = 7e-15
Identities = 37/61 (60%), Positives = 50/61 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SVFSGITLTK G+IVL F+++++F I+YF+MYL +VL+G HGL+ LPV L+ GPP
Sbjct: 1169 GSSVFSGITLTKFAGIIVLAFAKSQIFQIFYFRMYLCIVLVGAAHGLILLPVFLTYIGPP 1228
Query: 324 S 322
S
Sbjct: 1229 S 1229
[60][TOP]
>UniRef100_UPI000175F27F PREDICTED: im:7149020, partial n=1 Tax=Danio rerio
RepID=UPI000175F27F
Length = 598
Score = 83.2 bits (204), Expect = 9e-15
Identities = 37/60 (61%), Positives = 51/60 (85%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+++L S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 515 MGSSVFSGITLTKFGGILILALSKSQIFQIFYFRMYLAIVLLGAAHGLIFLPVLLSYAGP 574
[61][TOP]
>UniRef100_Q5BLA0 Npc1 protein (Fragment) n=2 Tax=Danio rerio RepID=Q5BLA0_DANRE
Length = 91
Score = 83.2 bits (204), Expect = 9e-15
Identities = 37/60 (61%), Positives = 51/60 (85%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G+++L S++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 8 MGSSVFSGITLTKFGGILILALSKSQIFQIFYFRMYLAIVLLGAAHGLIFLPVLLSYAGP 67
[62][TOP]
>UniRef100_Q9VL24 Niemann-Pick type C-1 n=1 Tax=Drosophila melanogaster
RepID=Q9VL24_DROME
Length = 1287
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1203 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1262
Query: 327 P 325
P
Sbjct: 1263 P 1263
[63][TOP]
>UniRef100_Q9U5W1 NPC1 protein n=1 Tax=Drosophila melanogaster RepID=Q9U5W1_DROME
Length = 1287
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1203 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1262
Query: 327 P 325
P
Sbjct: 1263 P 1263
[64][TOP]
>UniRef100_Q7YU59 RE56428p n=1 Tax=Drosophila melanogaster RepID=Q7YU59_DROME
Length = 1287
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1203 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1262
Query: 327 P 325
P
Sbjct: 1263 P 1263
[65][TOP]
>UniRef100_B4Q8Q7 GD22294 n=1 Tax=Drosophila simulans RepID=B4Q8Q7_DROSI
Length = 1251
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1167 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1226
Query: 327 P 325
P
Sbjct: 1227 P 1227
[66][TOP]
>UniRef100_B4NZ62 GE26328 n=1 Tax=Drosophila yakuba RepID=B4NZ62_DROYA
Length = 1287
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1203 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1262
Query: 327 P 325
P
Sbjct: 1263 P 1263
[67][TOP]
>UniRef100_B4KJH6 GI18274 (Fragment) n=1 Tax=Drosophila mojavensis RepID=B4KJH6_DROMO
Length = 1253
Score = 83.2 bits (204), Expect = 9e-15
Identities = 38/83 (45%), Positives = 58/83 (69%), Gaps = 7/83 (8%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MY +V++G HGL+FLPV+LS G
Sbjct: 1170 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYFGIVVIGATHGLIFLPVLLSYIGA 1229
Query: 327 PSRCTI-------IEQEENRSST 280
P+ + EQE + S T
Sbjct: 1230 PNNSRLESQNNENCEQETSLSGT 1252
[68][TOP]
>UniRef100_B4HWH4 GM11941 n=1 Tax=Drosophila sechellia RepID=B4HWH4_DROSE
Length = 1287
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1203 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1262
Query: 327 P 325
P
Sbjct: 1263 P 1263
[69][TOP]
>UniRef100_B3N938 GG23970 n=1 Tax=Drosophila erecta RepID=B3N938_DROER
Length = 1268
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1184 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1243
Query: 327 P 325
P
Sbjct: 1244 P 1244
[70][TOP]
>UniRef100_B3MPM8 GF14130 n=1 Tax=Drosophila ananassae RepID=B3MPM8_DROAN
Length = 1286
Score = 83.2 bits (204), Expect = 9e-15
Identities = 34/61 (55%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MYL +V++G HGL+FLPV+LS G
Sbjct: 1201 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSYIGA 1260
Query: 327 P 325
P
Sbjct: 1261 P 1261
[71][TOP]
>UniRef100_UPI000180C200 PREDICTED: similar to patched, partial n=1 Tax=Ciona intestinalis
RepID=UPI000180C200
Length = 271
Score = 82.8 bits (203), Expect = 1e-14
Identities = 37/63 (58%), Positives = 52/63 (82%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS GP
Sbjct: 157 IGSSVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLSYIGP 216
Query: 327 PSR 319
R
Sbjct: 217 RRR 219
[72][TOP]
>UniRef100_UPI000180B49C PREDICTED: Niemann-Pick disease, type C3 n=1 Tax=Ciona intestinalis
RepID=UPI000180B49C
Length = 1313
Score = 82.8 bits (203), Expect = 1e-14
Identities = 37/63 (58%), Positives = 52/63 (82%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS GP
Sbjct: 1199 IGSSVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLSYIGP 1258
Query: 327 PSR 319
R
Sbjct: 1259 RRR 1261
[73][TOP]
>UniRef100_UPI0000DB761D PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA isoform 2 n=1
Tax=Apis mellifera RepID=UPI0000DB761D
Length = 1358
Score = 82.8 bits (203), Expect = 1e-14
Identities = 36/61 (59%), Positives = 50/61 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G+IVL F+++++F ++YF+MYL +VL G HGL+FLPV+LS G
Sbjct: 1195 MGSSIFSGITLTKFGGIIVLGFAKSQIFKVFYFRMYLGIVLFGAAHGLIFLPVLLSYIGT 1254
Query: 327 P 325
P
Sbjct: 1255 P 1255
[74][TOP]
>UniRef100_UPI0000DB7411 PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA n=1 Tax=Apis
mellifera RepID=UPI0000DB7411
Length = 1238
Score = 82.8 bits (203), Expect = 1e-14
Identities = 34/58 (58%), Positives = 51/58 (87%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
G+SVFSGITLTK++G++VL F++T++F +++F+MYLS+V+ G HGL+FLPV+LS G
Sbjct: 1180 GSSVFSGITLTKIIGIVVLAFAKTQIFEVFFFRMYLSIVVFGAAHGLIFLPVLLSFIG 1237
[75][TOP]
>UniRef100_UPI0001758A11 PREDICTED: similar to niemann-pick C1 n=1 Tax=Tribolium castaneum
RepID=UPI0001758A11
Length = 1306
Score = 82.4 bits (202), Expect = 2e-14
Identities = 36/61 (59%), Positives = 50/61 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G+IVL F+++++F ++YF+MYL +VL G HGL+FLPV+LS G
Sbjct: 1221 MGSSIFSGITLTKFGGIIVLGFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSYVGT 1280
Query: 327 P 325
P
Sbjct: 1281 P 1281
[76][TOP]
>UniRef100_UPI0000E4A87C PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E4A87C
Length = 558
Score = 82.4 bits (202), Expect = 2e-14
Identities = 48/130 (36%), Positives = 73/130 (56%), Gaps = 11/130 (8%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SV SG+ +T L G+IVL F+++++FV++YF+M+L++ L+G +HGL+FLPVVLS GP
Sbjct: 414 MGSSVLSGVAMTNLPGIIVLAFAKSQLFVVFYFRMFLTITLVGTVHGLIFLPVVLSYIGP 473
Query: 327 PSRCTIIEQEENR-----------SSTSS*LYTFNHL*STGCFRRKRR*EAYQF*HVRYE 181
+ +++ R STS Y N + RK+ EA YE
Sbjct: 474 DVNLAYVLEDQERKDAEKLGNSEHGSTSKHAYDNNSIELEESGERKKEMEADD--PPGYE 531
Query: 180 TYIYDPLESI 151
I P S+
Sbjct: 532 VVIGAPTNSV 541
[77][TOP]
>UniRef100_UPI0000E48442 PREDICTED: similar to Niemann Pick type C1 n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48442
Length = 599
Score = 82.4 bits (202), Expect = 2e-14
Identities = 48/130 (36%), Positives = 73/130 (56%), Gaps = 11/130 (8%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SV SG+ +T L G+IVL F+++++FV++YF+M+L++ L+G +HGL+FLPVVLS GP
Sbjct: 455 MGSSVLSGVAMTNLPGIIVLAFAKSQLFVVFYFRMFLTITLVGTVHGLIFLPVVLSYIGP 514
Query: 327 PSRCTIIEQEENR-----------SSTSS*LYTFNHL*STGCFRRKRR*EAYQF*HVRYE 181
+ +++ R STS Y N + RK+ EA YE
Sbjct: 515 DVNLAYVLEDQERKDAEKLGNSEHGSTSKHAYDNNSIELEESGERKKEMEADD--PPGYE 572
Query: 180 TYIYDPLESI 151
I P S+
Sbjct: 573 VVIGAPTNSV 582
[78][TOP]
>UniRef100_Q17FP9 Niemann-pick C1 (Fragment) n=1 Tax=Aedes aegypti RepID=Q17FP9_AEDAE
Length = 1132
Score = 82.0 bits (201), Expect = 2e-14
Identities = 37/61 (60%), Positives = 50/61 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F ++YF+MYL +VL G HGLVFLPV+LS G
Sbjct: 909 MGSSVFSGITLTKFGGILVLGFAQSQIFQVFYFRMYLGIVLYGAAHGLVFLPVLLSYIGA 968
Query: 327 P 325
P
Sbjct: 969 P 969
[79][TOP]
>UniRef100_Q16VL3 Niemann-pick C1 n=1 Tax=Aedes aegypti RepID=Q16VL3_AEDAE
Length = 1266
Score = 82.0 bits (201), Expect = 2e-14
Identities = 37/66 (56%), Positives = 50/66 (75%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SVFSGITLTK G++VL F+ +++F I+YF+MYL +VL+G HGL+ LPV LS GP
Sbjct: 1180 GSSVFSGITLTKFAGIVVLAFANSQIFQIFYFRMYLGIVLIGAFHGLILLPVFLSYIGPR 1239
Query: 324 SRCTII 307
S +I
Sbjct: 1240 STKQVI 1245
[80][TOP]
>UniRef100_B7Q350 Niemann-Pick type C1 domain-containing protein, putative n=1
Tax=Ixodes scapularis RepID=B7Q350_IXOSC
Length = 1626
Score = 82.0 bits (201), Expect = 2e-14
Identities = 41/64 (64%), Positives = 52/64 (81%), Gaps = 3/64 (4%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS---I 337
MG+SV SGITLTK GV+VL FS +++F I+YF+MYLS+VL+G HGLVFLPV+LS +
Sbjct: 1124 MGSSVLSGITLTKFGGVVVLAFSTSQLFRIFYFRMYLSIVLIGAAHGLVFLPVLLSYAGV 1183
Query: 336 FGPP 325
GPP
Sbjct: 1184 VGPP 1187
[81][TOP]
>UniRef100_B4M8H0 GJ18108 n=1 Tax=Drosophila virilis RepID=B4M8H0_DROVI
Length = 1282
Score = 82.0 bits (201), Expect = 2e-14
Identities = 33/62 (53%), Positives = 51/62 (82%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+FSGITLTK G++VL F+++++F ++YF+MY +V++G HGL+FLPV+LS G
Sbjct: 1199 MGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYFGIVVIGATHGLIFLPVLLSYIGA 1258
Query: 327 PS 322
P+
Sbjct: 1259 PN 1260
[82][TOP]
>UniRef100_B4JXM3 GH17745 n=1 Tax=Drosophila grimshawi RepID=B4JXM3_DROGR
Length = 1246
Score = 82.0 bits (201), Expect = 2e-14
Identities = 39/77 (50%), Positives = 54/77 (70%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPVVLS+ GP
Sbjct: 1167 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVVLSLLGP- 1225
Query: 324 SRCTIIEQEENRSSTSS 274
+ +SST S
Sbjct: 1226 -----LNTRARKSSTKS 1237
[83][TOP]
>UniRef100_B0WCU9 Niemann-pick C1 n=1 Tax=Culex quinquefasciatus RepID=B0WCU9_CULQU
Length = 1645
Score = 82.0 bits (201), Expect = 2e-14
Identities = 37/61 (60%), Positives = 49/61 (80%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+ +++F ++YF+MYL +VL G HGLVFLPV+LS G
Sbjct: 1418 MGSSVFSGITLTKFGGILVLGFAHSQIFQVFYFRMYLGIVLFGAAHGLVFLPVLLSYIGA 1477
Query: 327 P 325
P
Sbjct: 1478 P 1478
[84][TOP]
>UniRef100_A8PPM6 Myosin head containing protein, putative n=1 Tax=Brugia malayi
RepID=A8PPM6_BRUMA
Length = 1548
Score = 82.0 bits (201), Expect = 2e-14
Identities = 35/61 (57%), Positives = 50/61 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SV SGITLTK G++VL F+ +++F ++YF+M+L +VL+G HGL+FLPV+LS GP
Sbjct: 463 MGSSVLSGITLTKFGGILVLAFAHSQIFKVFYFRMFLGIVLIGAAHGLIFLPVLLSYIGP 522
Query: 327 P 325
P
Sbjct: 523 P 523
[85][TOP]
>UniRef100_A7S0G1 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S0G1_NEMVE
Length = 1277
Score = 82.0 bits (201), Expect = 2e-14
Identities = 38/60 (63%), Positives = 49/60 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SV SGITLTK G+IVL F+++ +F I+YF+MY+ +VL G LHGLVFLPV+LS GP
Sbjct: 1195 MGSSVLSGITLTKFGGIIVLAFAKSRIFEIFYFRMYVGIVLFGALHGLVFLPVLLSYVGP 1254
[86][TOP]
>UniRef100_UPI0001758613 PREDICTED: similar to NPC1 protein n=1 Tax=Tribolium castaneum
RepID=UPI0001758613
Length = 1112
Score = 81.6 bits (200), Expect = 3e-14
Identities = 36/59 (61%), Positives = 50/59 (84%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG+SV SGITLTK G+IVL F+R+++F I++F+MYL +V++G LHGL+FLPV+LS G
Sbjct: 1035 MGSSVLSGITLTKFSGIIVLAFARSQIFQIFFFRMYLGIVIIGALHGLIFLPVLLSFLG 1093
[87][TOP]
>UniRef100_Q7Q409 AGAP008137-PA n=1 Tax=Anopheles gambiae RepID=Q7Q409_ANOGA
Length = 1192
Score = 81.6 bits (200), Expect = 3e-14
Identities = 37/61 (60%), Positives = 49/61 (80%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+ +++F ++YF+MYL +VL G HGLVFLPV+LS G
Sbjct: 1106 MGSSVFSGITLTKFGGILVLGFAHSQIFQVFYFRMYLGIVLYGAAHGLVFLPVLLSYIGA 1165
Query: 327 P 325
P
Sbjct: 1166 P 1166
[88][TOP]
>UniRef100_B4M3Q5 GJ19256 n=1 Tax=Drosophila virilis RepID=B4M3Q5_DROVI
Length = 1254
Score = 81.6 bits (200), Expect = 3e-14
Identities = 35/59 (59%), Positives = 49/59 (83%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G+IVL FS++++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1167 GSSVLSGITLTKFAGIIVLAFSKSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 1225
[89][TOP]
>UniRef100_B4H144 GL15811 n=1 Tax=Drosophila persimilis RepID=B4H144_DROPE
Length = 1250
Score = 81.6 bits (200), Expect = 3e-14
Identities = 37/62 (59%), Positives = 49/62 (79%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SV SGITLTK G++VL FS ++VF ++YF+MYL +VL+G HGL+ LPV+LS GP
Sbjct: 1172 GSSVLSGITLTKFAGIVVLGFSNSQVFQVFYFRMYLGIVLIGAAHGLILLPVLLSCMGPL 1231
Query: 324 SR 319
SR
Sbjct: 1232 SR 1233
[90][TOP]
>UniRef100_UPI0000E24CB3 PREDICTED: Niemann-Pick disease, type C1 isoform 1 n=1 Tax=Pan
troglodytes RepID=UPI0000E24CB3
Length = 1285
Score = 81.3 bits (199), Expect = 4e-14
Identities = 36/56 (64%), Positives = 50/56 (89%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
MG+SVFSGITLTK G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS
Sbjct: 1193 MGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLS 1248
[91][TOP]
>UniRef100_Q4RWY5 Chromosome 15 SCAF14981, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RWY5_TETNG
Length = 1209
Score = 81.3 bits (199), Expect = 4e-14
Identities = 36/59 (61%), Positives = 50/59 (84%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG+SVFSGITLTK G+++L S++++F ++YF+MYL++VLLG HGLVFLPV+LS G
Sbjct: 1151 MGSSVFSGITLTKFGGILILALSKSQIFQVFYFRMYLAIVLLGAAHGLVFLPVLLSYIG 1209
[92][TOP]
>UniRef100_Q29GK5 GA11389 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=Q29GK5_DROPS
Length = 1248
Score = 81.3 bits (199), Expect = 4e-14
Identities = 36/62 (58%), Positives = 49/62 (79%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SV SGITLTK G+++L FS ++VF ++YF+MYL +VL+G HGL+ LPV+LS GP
Sbjct: 1170 GSSVLSGITLTKFAGIVILGFSNSQVFQVFYFRMYLGIVLIGAAHGLILLPVLLSCMGPL 1229
Query: 324 SR 319
SR
Sbjct: 1230 SR 1231
[93][TOP]
>UniRef100_B4MSW0 GK19822 n=1 Tax=Drosophila willistoni RepID=B4MSW0_DROWI
Length = 1264
Score = 81.3 bits (199), Expect = 4e-14
Identities = 36/59 (61%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS ++VF I+YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1186 GSSVLSGITLTKFAGIVVLAFSNSQVFQIFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 1244
[94][TOP]
>UniRef100_C5PGL6 Patched family protein n=1 Tax=Coccidioides posadasii C735 delta
SOWgp RepID=C5PGL6_COCP7
Length = 1271
Score = 81.3 bits (199), Expect = 4e-14
Identities = 37/59 (62%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGITLTKLVGV VL F+R+++F IYYF+++L+L++ HGL+FLPV LS FG
Sbjct: 1177 VGGSVFSGITLTKLVGVCVLAFTRSKIFEIYYFRVWLALIIFAATHGLIFLPVALSFFG 1235
[95][TOP]
>UniRef100_C4JHE8 Putative uncharacterized protein n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JHE8_UNCRE
Length = 1271
Score = 81.3 bits (199), Expect = 4e-14
Identities = 37/59 (62%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGITLTKLVGV VL F+R+++F IYYF+++L+L++ HGL+FLPV LS FG
Sbjct: 1177 VGGSVFSGITLTKLVGVCVLAFTRSKIFEIYYFRVWLALIIFAATHGLIFLPVALSFFG 1235
[96][TOP]
>UniRef100_B3S409 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
adhaerens RepID=B3S409_TRIAD
Length = 1218
Score = 80.9 bits (198), Expect = 5e-14
Identities = 36/59 (61%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG+SVFSGITLTK G+IVL F+++++F I+YF+MYL +V+ G HGL+FLP LS FG
Sbjct: 1144 MGSSVFSGITLTKFGGIIVLAFAKSQIFEIFYFRMYLGIVIFGASHGLIFLPAFLSFFG 1202
[97][TOP]
>UniRef100_B3N0K3 GF21705 n=1 Tax=Drosophila ananassae RepID=B3N0K3_DROAN
Length = 1323
Score = 80.5 bits (197), Expect = 6e-14
Identities = 36/76 (47%), Positives = 52/76 (68%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1161 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLMGPL 1220
Query: 324 SRCTIIEQEENRSSTS 277
++ S S
Sbjct: 1221 DSLNRTSEDPRTSQAS 1236
[98][TOP]
>UniRef100_B4R3B9 GD17504 n=1 Tax=Drosophila simulans RepID=B4R3B9_DROSI
Length = 170
Score = 80.1 bits (196), Expect = 8e-14
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 91 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 149
[99][TOP]
>UniRef100_B4PYK8 GE17898 n=1 Tax=Drosophila yakuba RepID=B4PYK8_DROYA
Length = 1252
Score = 80.1 bits (196), Expect = 8e-14
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1174 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 1232
[100][TOP]
>UniRef100_B4L379 GI15499 n=1 Tax=Drosophila mojavensis RepID=B4L379_DROMO
Length = 1217
Score = 80.1 bits (196), Expect = 8e-14
Identities = 36/59 (61%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS+++VF I+YF+MYL +VL+G HGL+ LPV+LS GP
Sbjct: 1150 GSSVLSGITLTKFAGIVVLAFSKSQVFQIFYFRMYLGIVLIGAAHGLILLPVLLSQLGP 1208
[101][TOP]
>UniRef100_B4I6C1 GM23054 n=1 Tax=Drosophila sechellia RepID=B4I6C1_DROSE
Length = 1228
Score = 80.1 bits (196), Expect = 8e-14
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1149 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 1207
[102][TOP]
>UniRef100_B3NY50 GG19701 n=1 Tax=Drosophila erecta RepID=B3NY50_DROER
Length = 1248
Score = 80.1 bits (196), Expect = 8e-14
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
G+SV SGITLTK G++VL FS +++F ++YF+MYL +VL+G HGL+ LPV+LS+ GP
Sbjct: 1174 GSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGP 1232
[103][TOP]
>UniRef100_B0X6W3 Niemann-Pick C1 protein n=1 Tax=Culex quinquefasciatus
RepID=B0X6W3_CULQU
Length = 1097
Score = 80.1 bits (196), Expect = 8e-14
Identities = 37/61 (60%), Positives = 47/61 (77%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPP 325
G SVFSGITLTK G+IVL F+ +++F I+YF+MYL +VL+G HGL+ LPV LS GP
Sbjct: 1004 GRSVFSGITLTKFAGIIVLAFANSQIFQIFYFRMYLGIVLIGAAHGLILLPVFLSYVGPR 1063
Query: 324 S 322
S
Sbjct: 1064 S 1064
[104][TOP]
>UniRef100_UPI0001924FA3 PREDICTED: similar to predicted protein, partial n=1 Tax=Hydra
magnipapillata RepID=UPI0001924FA3
Length = 1289
Score = 79.7 bits (195), Expect = 1e-13
Identities = 39/75 (52%), Positives = 57/75 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SV SGI GV VL F+++++F IYYF+MY+ L+L+G +HG VFLPV+LS FGP
Sbjct: 1207 VGSSVLSGI------GVFVLLFAKSQMFKIYYFRMYMGLILIGAIHGFVFLPVLLSFFGP 1260
Query: 327 PSRCTIIEQEENRSS 283
SRCT E++ +R++
Sbjct: 1261 ASRCT--EEDISRAA 1273
[105][TOP]
>UniRef100_UPI000069E05A Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05A
Length = 1319
Score = 79.7 bits (195), Expect = 1e-13
Identities = 35/72 (48%), Positives = 57/72 (79%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G+IVL F++ ++ I++F++ L++ LLG +HGL+FLPVVLS FGP
Sbjct: 1245 MGSAVFAGVAMTNLPGIIVLAFAKAQLIQIFFFRLNLTITLLGLVHGLIFLPVVLSYFGP 1304
Query: 327 P-SRCTIIEQEE 295
+R ++EQ+E
Sbjct: 1305 GINRAVLLEQQE 1316
[106][TOP]
>UniRef100_UPI0000E48D84 PREDICTED: similar to Niemann-Pick C disease protein n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E48D84
Length = 705
Score = 79.3 bits (194), Expect = 1e-13
Identities = 33/61 (54%), Positives = 51/61 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SV SG+ +T L G+IVL F+++++FV++YF+M+L++ L+G +HGL+FLPVVLS G
Sbjct: 554 MGSSVLSGVAMTNLPGIIVLAFAKSQLFVVFYFRMFLTITLVGTVHGLIFLPVVLSYIGK 613
Query: 327 P 325
P
Sbjct: 614 P 614
[107][TOP]
>UniRef100_UPI000023DFE9 hypothetical protein FG09254.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DFE9
Length = 1295
Score = 78.6 bits (192), Expect = 2e-13
Identities = 38/59 (64%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++LSLV+ LH LVFLPV LSI G
Sbjct: 1200 VGGSVFSGITVTKLLGVSVLAFTRSKIFEIYYFRVWLSLVIFAALHALVFLPVALSIAG 1258
[108][TOP]
>UniRef100_C4QWB0 Vacuolar membrane protein that transits through the biosynthetic
vacuolar protein sorting pathway n=1 Tax=Pichia pastoris
GS115 RepID=C4QWB0_PICPG
Length = 1284
Score = 78.6 bits (192), Expect = 2e-13
Identities = 36/59 (61%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVF GITLTK+VGV VL F+R+++F +YYF+M+ SLV+L LH L+FLPV+LS G
Sbjct: 1199 IGGSVFGGITLTKIVGVTVLAFTRSQIFEVYYFRMWFSLVVLASLHSLMFLPVILSYVG 1257
[109][TOP]
>UniRef100_A1DN50 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Neosartorya
fischeri NRRL 181 RepID=A1DN50_NEOFI
Length = 1273
Score = 78.6 bits (192), Expect = 2e-13
Identities = 36/59 (61%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPVVLS FG
Sbjct: 1179 VGGSVFSGITITKLLGVCVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVVLSYFG 1237
[110][TOP]
>UniRef100_Q9GK52 Niemann-Pick type C1 disease protein n=1 Tax=Canis lupus familiaris
RepID=Q9GK52_CANFA
Length = 1276
Score = 78.2 bits (191), Expect = 3e-13
Identities = 35/60 (58%), Positives = 49/60 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+SVFSGITLTK G++VL F+++++F ++ MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1192 MGSSVFSGITLTKFGGIVVLAFAKSQIFQVFITGMYLAMVLLGATHGLIFLPVLLSYIGP 1251
[111][TOP]
>UniRef100_Q5C0X8 SJCHGC06092 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5C0X8_SCHJA
Length = 182
Score = 77.4 bits (189), Expect = 5e-13
Identities = 41/90 (45%), Positives = 58/90 (64%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+ GITLTKL G++VL S++ +F I+YF+MYLS++L G GL+ LPV LS FGP
Sbjct: 91 MGSSILRGITLTKLGGIVVLAASKSRLFQIFYFRMYLSMILFGAFTGLIILPVYLSYFGP 150
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNHL*STG 238
+ + NRS+++ N L TG
Sbjct: 151 --KLNLAMSSSNRSNSNHSSSNNNDLQPTG 178
[112][TOP]
>UniRef100_C7Z5H5 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z5H5_NECH7
Length = 1272
Score = 77.4 bits (189), Expect = 5e-13
Identities = 37/59 (62%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ LH LVFLPV LSI G
Sbjct: 1177 VGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALVVFAALHALVFLPVALSIAG 1235
[113][TOP]
>UniRef100_C5JHY3 Patched sphingolipid transporter n=1 Tax=Ajellomyces dermatitidis
SLH14081 RepID=C5JHY3_AJEDS
Length = 1274
Score = 77.4 bits (189), Expect = 5e-13
Identities = 35/64 (54%), Positives = 50/64 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1180 VGSSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFFGG 1239
Query: 327 PSRC 316
C
Sbjct: 1240 DGYC 1243
[114][TOP]
>UniRef100_C5GGT7 Patched sphingolipid transporter n=1 Tax=Ajellomyces dermatitidis
ER-3 RepID=C5GGT7_AJEDR
Length = 1274
Score = 77.4 bits (189), Expect = 5e-13
Identities = 35/64 (54%), Positives = 50/64 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1180 VGSSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFFGG 1239
Query: 327 PSRC 316
C
Sbjct: 1240 DGYC 1243
[115][TOP]
>UniRef100_A1CTG5 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
clavatus RepID=A1CTG5_ASPCL
Length = 1274
Score = 77.4 bits (189), Expect = 5e-13
Identities = 35/59 (59%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV+LS FG
Sbjct: 1180 VGGSVFSGITITKLLGVCVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVMLSYFG 1238
[116][TOP]
>UniRef100_Q4WMG5 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
fumigatus RepID=Q4WMG5_ASPFU
Length = 1273
Score = 77.0 bits (188), Expect = 7e-13
Identities = 34/59 (57%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+G+ VL F+R+++F IYYF+++L+LV+ H L+FLPV+LS FG
Sbjct: 1179 VGGSVFSGITITKLLGICVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVLLSYFG 1237
[117][TOP]
>UniRef100_Q2U2G2 Cholesterol transport protein n=1 Tax=Aspergillus oryzae
RepID=Q2U2G2_ASPOR
Length = 1163
Score = 77.0 bits (188), Expect = 7e-13
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+L+L H L+FLPV LS FG
Sbjct: 1069 VGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALILFAATHALIFLPVALSYFG 1127
[118][TOP]
>UniRef100_C9SSK3 Niemann-Pick C1 protein n=1 Tax=Verticillium albo-atrum VaMs.102
RepID=C9SSK3_9PEZI
Length = 158
Score = 77.0 bits (188), Expect = 7e-13
Identities = 35/59 (59%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+GASVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS+ G
Sbjct: 63 VGASVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVALSLLG 121
[119][TOP]
>UniRef100_B8NIY3 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
flavus NRRL3357 RepID=B8NIY3_ASPFN
Length = 1147
Score = 77.0 bits (188), Expect = 7e-13
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+L+L H L+FLPV LS FG
Sbjct: 1053 VGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALILFAATHALIFLPVALSYFG 1111
[120][TOP]
>UniRef100_B6QA78 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Penicillium
marneffei ATCC 18224 RepID=B6QA78_PENMQ
Length = 1269
Score = 77.0 bits (188), Expect = 7e-13
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1174 VGGSVFSGITITKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAATHALIFLPVALSYFG 1232
[121][TOP]
>UniRef100_B0Y842 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Aspergillus
fumigatus A1163 RepID=B0Y842_ASPFC
Length = 1273
Score = 77.0 bits (188), Expect = 7e-13
Identities = 34/59 (57%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+G+ VL F+R+++F IYYF+++L+LV+ H L+FLPV+LS FG
Sbjct: 1179 VGGSVFSGITITKLLGICVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVLLSYFG 1237
[122][TOP]
>UniRef100_A2QWF9 Remark: Niemann-Pick C n=1 Tax=Aspergillus niger CBS 513.88
RepID=A2QWF9_ASPNC
Length = 1277
Score = 77.0 bits (188), Expect = 7e-13
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+L+L H L+FLPV LS FG
Sbjct: 1183 VGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALILFAATHALIFLPVALSYFG 1241
[123][TOP]
>UniRef100_B8M187 Patched sphingolipid transporter (Ncr1), putative n=1 Tax=Talaromyces
stipitatus ATCC 10500 RepID=B8M187_TALSN
Length = 1269
Score = 76.6 bits (187), Expect = 9e-13
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1174 VGGSVFSGITITKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSYFG 1232
[124][TOP]
>UniRef100_Q2GRY0 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2GRY0_CHAGB
Length = 1181
Score = 76.3 bits (186), Expect = 1e-12
Identities = 34/59 (57%), Positives = 49/59 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TK++GV VL F+R+++F IYYF+++++LV+ H LVFLPV LS+FG
Sbjct: 1085 VGGSVFSGITITKVLGVAVLAFTRSKIFEIYYFRVWVALVIFAATHALVFLPVALSLFG 1143
[125][TOP]
>UniRef100_C8VM00 Putative uncharacterized protein n=2 Tax=Emericella nidulans
RepID=C8VM00_EMENI
Length = 1271
Score = 76.3 bits (186), Expect = 1e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++L+L++ H L+FLPV LS FG
Sbjct: 1177 VGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALIIFAATHALIFLPVALSYFG 1235
[126][TOP]
>UniRef100_UPI000186F3A4 Niemann-Pick C1 protein precursor, putative n=1 Tax=Pediculus humanus
corporis RepID=UPI000186F3A4
Length = 1233
Score = 75.9 bits (185), Expect = 1e-12
Identities = 35/59 (59%), Positives = 47/59 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG SVFSGITLTK +G+IVL F++T + +YF+MYL +VL+G +HGL+ LPV+LS G
Sbjct: 1175 MGTSVFSGITLTKFLGIIVLAFAQTLMLRTFYFKMYLGIVLIGAIHGLILLPVLLSYVG 1233
[127][TOP]
>UniRef100_Q5KGS9 Vacuolar membrane protein, putative n=1 Tax=Filobasidiella neoformans
RepID=Q5KGS9_CRYNE
Length = 1330
Score = 75.9 bits (185), Expect = 1e-12
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+G+ VL +R+++ +YYF+M+LSL+L G LHGLV LPV+LS G
Sbjct: 1235 VGPSVFSGITMTKLIGISVLALTRSKLLEVYYFRMWLSLILSGALHGLVLLPVLLSYLG 1293
[128][TOP]
>UniRef100_Q55SD4 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
RepID=Q55SD4_CRYNE
Length = 1330
Score = 75.9 bits (185), Expect = 1e-12
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+G+ VL +R+++ +YYF+M+LSL+L G LHGLV LPV+LS G
Sbjct: 1235 VGPSVFSGITMTKLIGISVLALTRSKLLEVYYFRMWLSLILSGALHGLVLLPVLLSYLG 1293
[129][TOP]
>UniRef100_UPI000180CC29 PREDICTED: Niemann-Pick disease, type C1 n=1 Tax=Ciona intestinalis
RepID=UPI000180CC29
Length = 1366
Score = 75.5 bits (184), Expect = 2e-12
Identities = 38/80 (47%), Positives = 54/80 (67%), Gaps = 2/80 (2%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG +VF+G+ LT L G+IVL ++ ++ I++F+M L + LLG HGL+FLPV LS FGP
Sbjct: 1248 MGPAVFAGVALTNLPGIIVLNWATAQLIQIFFFRMCLVITLLGTAHGLIFLPVFLSYFGP 1307
Query: 327 PSRCTII--EQEENRSSTSS 274
P I+ EQ E R +T +
Sbjct: 1308 PVNKAILYEEQSELRKATQT 1327
[130][TOP]
>UniRef100_Q4H344 Niemann-Pick disease, type C1 (Fragment) n=1 Tax=Ciona intestinalis
RepID=Q4H344_CIOIN
Length = 620
Score = 75.5 bits (184), Expect = 2e-12
Identities = 38/80 (47%), Positives = 54/80 (67%), Gaps = 2/80 (2%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG +VF+G+ LT L G+IVL ++ ++ I++F+M L + LLG HGL+FLPV LS FGP
Sbjct: 502 MGPAVFAGVALTNLPGIIVLNWATAQLIQIFFFRMCLVITLLGTAHGLIFLPVFLSYFGP 561
Query: 327 PSRCTII--EQEENRSSTSS 274
P I+ EQ E R +T +
Sbjct: 562 PVNKAILYEEQSELRKATQT 581
[131][TOP]
>UniRef100_B7PPF5 Niemann-Pick type C1 domain-containing protein, putative n=1
Tax=Ixodes scapularis RepID=B7PPF5_IXOSC
Length = 1233
Score = 75.5 bits (184), Expect = 2e-12
Identities = 33/61 (54%), Positives = 48/61 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+ SGITLT G++VL F+++++F ++YF+MYL ++ G LH L+FLPV LSI GP
Sbjct: 1137 MGSSILSGITLTDC-GILVLAFAKSQIFQVFYFRMYLGIIAFGTLHSLIFLPVFLSILGP 1195
Query: 327 P 325
P
Sbjct: 1196 P 1196
[132][TOP]
>UniRef100_Q0CK25 Putative uncharacterized protein n=1 Tax=Aspergillus terreus NIH2624
RepID=Q0CK25_ASPTN
Length = 1263
Score = 75.5 bits (184), Expect = 2e-12
Identities = 34/59 (57%), Positives = 47/59 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGITLTKL+GV VL F+ +++F IYYF+++L+L++ H L+FLPV LS FG
Sbjct: 1169 VGGSVFSGITLTKLLGVCVLAFTHSKIFEIYYFRVWLALIIFAATHALIFLPVALSYFG 1227
[133][TOP]
>UniRef100_C1GRY4 Patched sphingolipid transporter (Ncr1) n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GRY4_PARBA
Length = 1266
Score = 75.5 bits (184), Expect = 2e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1171 VGGSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFFG 1229
[134][TOP]
>UniRef100_C1G8F9 Niemann-Pick C1 protein n=1 Tax=Paracoccidioides brasiliensis Pb18
RepID=C1G8F9_PARBD
Length = 1235
Score = 75.5 bits (184), Expect = 2e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1171 VGGSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFFG 1229
[135][TOP]
>UniRef100_C0S090 Niemann-Pick C1 protein n=1 Tax=Paracoccidioides brasiliensis Pb03
RepID=C0S090_PARBP
Length = 1235
Score = 75.5 bits (184), Expect = 2e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1171 VGGSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFFG 1229
[136][TOP]
>UniRef100_B6HDY6 Pc20g15300 protein n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6HDY6_PENCW
Length = 1275
Score = 75.5 bits (184), Expect = 2e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G +VFSGIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS FG
Sbjct: 1181 VGGTVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALVIFAATHALIFLPVALSYFG 1239
[137][TOP]
>UniRef100_Q750G1 AGL008Wp n=1 Tax=Eremothecium gossypii RepID=Q750G1_ASHGO
Length = 1178
Score = 75.1 bits (183), Expect = 3e-12
Identities = 31/62 (50%), Positives = 49/62 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SVF GIT+TKL+GV +L+F+++++F ++YF+M+LSL+L+ LH L+FLP L+ G
Sbjct: 1103 VGESVFRGITMTKLIGVCILFFAQSKIFQVFYFRMWLSLILIASLHALIFLPTALAFLGG 1162
Query: 327 PS 322
S
Sbjct: 1163 QS 1164
[138][TOP]
>UniRef100_C6HD90 Patched sphingolipid transporter n=1 Tax=Ajellomyces capsulatus H143
RepID=C6HD90_AJECH
Length = 1061
Score = 75.1 bits (183), Expect = 3e-12
Identities = 34/64 (53%), Positives = 49/64 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS G
Sbjct: 967 VGSSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFLGG 1026
Query: 327 PSRC 316
C
Sbjct: 1027 DGYC 1030
[139][TOP]
>UniRef100_C0NRZ7 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NRZ7_AJECG
Length = 892
Score = 75.1 bits (183), Expect = 3e-12
Identities = 34/64 (53%), Positives = 49/64 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS G
Sbjct: 798 VGSSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFLGG 857
Query: 327 PSRC 316
C
Sbjct: 858 DGYC 861
[140][TOP]
>UniRef100_A7EA90 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EA90_SCLS1
Length = 1252
Score = 75.1 bits (183), Expect = 3e-12
Identities = 35/59 (59%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKLVGV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS+ G
Sbjct: 1159 VGGSVFSGITITKLVGVSVLAFTRSKIFEIYYFRIWLALVIFAASHALMFLPVALSLVG 1217
[141][TOP]
>UniRef100_A6RA01 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus NAm1
RepID=A6RA01_AJECN
Length = 1181
Score = 75.1 bits (183), Expect = 3e-12
Identities = 34/64 (53%), Positives = 49/64 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G+SVF+GIT+TKL+GV VL F+R+++F IYYF+++L+LV+ H L+FLPV LS G
Sbjct: 1087 VGSSVFTGITVTKLLGVCVLAFTRSKIFEIYYFRIWLALVIFAASHALIFLPVALSFLGG 1146
Query: 327 PSRC 316
C
Sbjct: 1147 DGYC 1150
[142][TOP]
>UniRef100_UPI00017B4C1E UPI00017B4C1E related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B4C1E
Length = 1213
Score = 74.7 bits (182), Expect = 3e-12
Identities = 32/76 (42%), Positives = 54/76 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL F++ ++ I++F++ L + LLG HGL+FLPV+LS FGP
Sbjct: 1130 MGSAVFAGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGMAHGLIFLPVLLSYFGP 1189
Query: 327 PSRCTIIEQEENRSST 280
I+ Q++ +T
Sbjct: 1190 SVNKAILLQQDELKTT 1205
[143][TOP]
>UniRef100_Q66NT1 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NT1_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[144][TOP]
>UniRef100_Q66NS9 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS9_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[145][TOP]
>UniRef100_Q66NS4 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS4_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[146][TOP]
>UniRef100_Q66NS3 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS3_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[147][TOP]
>UniRef100_Q66NR8 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR8_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[148][TOP]
>UniRef100_Q66NR7 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR7_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[149][TOP]
>UniRef100_Q66NR4 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR4_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[150][TOP]
>UniRef100_Q66NR2 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NR2_CIOIN
Length = 371
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/53 (62%), Positives = 46/53 (86%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGITLTK VG+++L FS++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITLTKFVGIVILAFSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[151][TOP]
>UniRef100_Q7RWL9 Putative uncharacterized protein n=1 Tax=Neurospora crassa
RepID=Q7RWL9_NEUCR
Length = 1162
Score = 74.3 bits (181), Expect = 4e-12
Identities = 34/59 (57%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++++LV+ H LVFLPV LS+ G
Sbjct: 1066 VGGSVFSGITVTKLLGVFVLGFTRSKIFEIYYFRIWVALVIFAATHALVFLPVALSLVG 1124
[152][TOP]
>UniRef100_A4RE01 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4RE01_MAGGR
Length = 1275
Score = 74.3 bits (181), Expect = 4e-12
Identities = 33/59 (55%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TKL+GV VL F+R+++F IYYF+++++LV+ H L+FLPV LS+ G
Sbjct: 1181 VGGSVFSGITVTKLLGVTVLAFTRSKIFEIYYFRVWVALVIFAATHALIFLPVALSLLG 1239
[153][TOP]
>UniRef100_C4Q7T0 Niemann-pick C1 (NPC1) n=1 Tax=Schistosoma mansoni RepID=C4Q7T0_SCHMA
Length = 950
Score = 73.9 bits (180), Expect = 6e-12
Identities = 39/85 (45%), Positives = 55/85 (64%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+S+ GITLTKL G++VL S++ +F I+YF+MYLS++L G GL+ LPV LS GP
Sbjct: 861 MGSSILRGITLTKLGGIVVLAASKSRLFQIFYFRMYLSMILFGAFTGLIILPVYLSYLGP 920
Query: 327 PSRCTIIEQEENRSSTSS*LYTFNH 253
+ N + +SS +T NH
Sbjct: 921 ---------KLNLAMSSSRPHTINH 936
[154][TOP]
>UniRef100_C5MCB4 Putative uncharacterized protein n=1 Tax=Candida tropicalis MYA-3404
RepID=C5MCB4_CANTT
Length = 1259
Score = 73.9 bits (180), Expect = 6e-12
Identities = 30/57 (52%), Positives = 48/57 (84%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSI 337
+G S+ SG+TLTK++G+ VL F+R+++F +YYF+M+LSLV++ F+H V LPV+LS+
Sbjct: 1203 VGGSLISGVTLTKIIGITVLAFTRSQIFEVYYFRMWLSLVVISFVHAFVLLPVLLSL 1259
[155][TOP]
>UniRef100_A8NWN7 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NWN7_COPC7
Length = 1382
Score = 73.9 bits (180), Expect = 6e-12
Identities = 35/61 (57%), Positives = 48/61 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G +V SGIT TKL+G+ VL +R+++ IYYF+M+L+L++ G LHGLV LPVVLSI G
Sbjct: 1289 VGPAVLSGITFTKLIGMCVLALTRSKLLEIYYFRMWLTLIISGALHGLVLLPVVLSIAGG 1348
Query: 327 P 325
P
Sbjct: 1349 P 1349
[156][TOP]
>UniRef100_A7TSK4 Putative uncharacterized protein (Fragment) n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TSK4_VANPO
Length = 826
Score = 73.9 bits (180), Expect = 6e-12
Identities = 32/75 (42%), Positives = 55/75 (73%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SVF+GIT+TKL+GV +L F+++++F ++YF+M+L+L+ + +H L+FLPV+LS+ G
Sbjct: 751 VGKSVFTGITITKLIGVSILAFAQSQIFQVFYFRMWLALIFVAAIHALIFLPVLLSMIGG 810
Query: 327 PSRCTIIEQEENRSS 283
+ + E SS
Sbjct: 811 TAYIDNLANENTVSS 825
[157][TOP]
>UniRef100_Q59ZV0 Potential sterol homeostasis protein n=1 Tax=Candida albicans
RepID=Q59ZV0_CANAL
Length = 1256
Score = 73.6 bits (179), Expect = 7e-12
Identities = 31/56 (55%), Positives = 47/56 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
+G S+ SG+TLTKL+G+ VL F+R+++F +YYF+M+LSLV++ F+H V LPV+LS
Sbjct: 1200 VGGSLISGVTLTKLIGISVLAFTRSQIFEVYYFRMWLSLVVISFVHAFVLLPVLLS 1255
[158][TOP]
>UniRef100_C4YFP8 Putative uncharacterized protein n=1 Tax=Candida albicans
RepID=C4YFP8_CANAL
Length = 1256
Score = 73.6 bits (179), Expect = 7e-12
Identities = 31/56 (55%), Positives = 47/56 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
+G S+ SG+TLTKL+G+ VL F+R+++F +YYF+M+LSLV++ F+H V LPV+LS
Sbjct: 1200 VGGSLISGVTLTKLIGISVLAFTRSQIFEVYYFRMWLSLVVISFVHAFVLLPVLLS 1255
[159][TOP]
>UniRef100_B9WA46 Sterol homeostasis regulator, putative n=1 Tax=Candida dubliniensis
CD36 RepID=B9WA46_CANDC
Length = 1240
Score = 73.6 bits (179), Expect = 7e-12
Identities = 31/56 (55%), Positives = 47/56 (83%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
+G S+ SG+TLTKL+G+ VL F+R+++F +YYF+M+LSLV++ F+H V LPV+LS
Sbjct: 1184 VGGSLISGVTLTKLIGISVLAFTRSQIFEVYYFRMWLSLVVISFVHAFVLLPVLLS 1239
[160][TOP]
>UniRef100_UPI000187E5E1 hypothetical protein MPER_05669 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187E5E1
Length = 163
Score = 73.2 bits (178), Expect = 1e-11
Identities = 35/59 (59%), Positives = 47/59 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV SGIT TKL+G+ VL +R+++ IYYF+M+L+L++ G LHGLV LPVVLSI G
Sbjct: 68 VGPSVLSGITFTKLIGMCVLALTRSKLLEIYYFRMWLTLIISGALHGLVLLPVVLSIAG 126
[161][TOP]
>UniRef100_C5FQM2 Niemann-Pick C1 protein n=1 Tax=Microsporum canis CBS 113480
RepID=C5FQM2_NANOT
Length = 1270
Score = 73.2 bits (178), Expect = 1e-11
Identities = 33/59 (55%), Positives = 46/59 (77%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV SGIT+TKLVG+ VL F+R+++F IYYF+++L+LV+ H L+FLPV LS G
Sbjct: 1173 VGGSVLSGITITKLVGICVLAFTRSKIFEIYYFRVWLALVIFAAAHALIFLPVALSFVG 1231
[162][TOP]
>UniRef100_Q6T3U3 Niemann-Pick C1-like protein 1 n=1 Tax=Rattus norvegicus
RepID=NPCL1_RAT
Length = 1331
Score = 73.2 bits (178), Expect = 1e-11
Identities = 31/77 (40%), Positives = 54/77 (70%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T G+++L F++ ++ I++F++ L + LLG LHGLVFLPVVLS GP
Sbjct: 1209 MGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGP 1268
Query: 327 PSRCTIIEQEENRSSTS 277
++++E+ S +
Sbjct: 1269 DVNQALVQEEKLASEAA 1285
[163][TOP]
>UniRef100_UPI00016E1F21 UPI00016E1F21 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F21
Length = 1289
Score = 72.8 bits (177), Expect = 1e-11
Identities = 33/78 (42%), Positives = 57/78 (73%), Gaps = 3/78 (3%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL F++ ++ I++F++ L + LLG +HGLVFLPV+LS FGP
Sbjct: 1205 MGSAVFAGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGLVHGLVFLPVLLSYFGP 1264
Query: 327 PSRCTI---IEQEENRSS 283
+ ++QE+ R++
Sbjct: 1265 GVNKAVLLRLQQEDLRTT 1282
[164][TOP]
>UniRef100_C5DXD6 ZYRO0F04180p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5DXD6_ZYGRC
Length = 1180
Score = 72.8 bits (177), Expect = 1e-11
Identities = 31/62 (50%), Positives = 49/62 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SVF GIT+TK +GV VL F+++++F ++YF+M+ SL++L +H LVFLP++LS+ G
Sbjct: 1101 VGDSVFKGITMTKFIGVCVLAFAKSKIFQVFYFRMWFSLIILASVHALVFLPILLSLAGG 1160
Query: 327 PS 322
S
Sbjct: 1161 KS 1162
[165][TOP]
>UniRef100_UPI00005BC4A6 PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Bos taurus RepID=UPI00005BC4A6
Length = 1333
Score = 72.4 bits (176), Expect = 2e-11
Identities = 29/78 (37%), Positives = 55/78 (70%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + +LG LHGLVFLPV+LS GP
Sbjct: 1210 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITVLGLLHGLVFLPVILSYLGP 1269
Query: 327 PSRCTIIEQEENRSSTSS 274
+++Q++ + ++
Sbjct: 1270 DVNPALVQQQKQQEEAAA 1287
[166][TOP]
>UniRef100_UPI00019513D7 UPI00019513D7 related cluster n=1 Tax=Bos taurus RepID=UPI00019513D7
Length = 1324
Score = 72.4 bits (176), Expect = 2e-11
Identities = 29/78 (37%), Positives = 55/78 (70%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + +LG LHGLVFLPV+LS GP
Sbjct: 1235 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITVLGLLHGLVFLPVILSYLGP 1294
Query: 327 PSRCTIIEQEENRSSTSS 274
+++Q++ + ++
Sbjct: 1295 DVNPALVQQQKQQEEAAA 1312
[167][TOP]
>UniRef100_UPI0000F2B5DF PREDICTED: similar to Niemann-Pick C1-like 1 protein n=1
Tax=Monodelphis domestica RepID=UPI0000F2B5DF
Length = 1331
Score = 72.0 bits (175), Expect = 2e-11
Identities = 32/79 (40%), Positives = 55/79 (69%), Gaps = 1/79 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G+I+L ++ ++ I++F++ L + + G LHGLVFLPV+LS FGP
Sbjct: 1203 MGSAVFAGVAMTNLPGIIILAAAKAQLIQIFFFRLNLLITIFGMLHGLVFLPVILSYFGP 1262
Query: 327 P-SRCTIIEQEENRSSTSS 274
+ ++EQ+ +T S
Sbjct: 1263 DVKQVLVLEQQPIEKNTMS 1281
[168][TOP]
>UniRef100_UPI000069E05C Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05C
Length = 1228
Score = 72.0 bits (175), Expect = 2e-11
Identities = 30/59 (50%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG++VF+G+ +T L G+IVL F++ ++ I++F++ L++ LLG +HGL+FLPVVLS FG
Sbjct: 1144 MGSAVFAGVAMTNLPGIIVLAFAKAQLIQIFFFRLNLTITLLGLVHGLIFLPVVLSYFG 1202
[169][TOP]
>UniRef100_UPI000069E05B Niemann-Pick C1-like protein 1 precursor. n=1 Tax=Xenopus (Silurana)
tropicalis RepID=UPI000069E05B
Length = 1260
Score = 72.0 bits (175), Expect = 2e-11
Identities = 30/59 (50%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG++VF+G+ +T L G+IVL F++ ++ I++F++ L++ LLG +HGL+FLPVVLS FG
Sbjct: 1202 MGSAVFAGVAMTNLPGIIVLAFAKAQLIQIFFFRLNLTITLLGLVHGLIFLPVVLSYFG 1260
[170][TOP]
>UniRef100_C4Y974 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
42720 RepID=C4Y974_CLAL4
Length = 1250
Score = 72.0 bits (175), Expect = 2e-11
Identities = 33/59 (55%), Positives = 45/59 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV GITLTKL+GV VL F+R+++F +YYF+M+L+LV + H LV LPV LS+ G
Sbjct: 1192 VGGSVIGGITLTKLIGVAVLAFARSKIFEVYYFRMWLALVAIAAAHSLVLLPVALSMLG 1250
[171][TOP]
>UniRef100_B2APT9 Predicted CDS Pa_4_6310 n=1 Tax=Podospora anserina RepID=B2APT9_PODAN
Length = 1278
Score = 72.0 bits (175), Expect = 2e-11
Identities = 33/59 (55%), Positives = 48/59 (81%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVFSGIT+TK++GV VL F+R+++F IYYF+++++LV+ H LVFLPV LS+ G
Sbjct: 1183 VGGSVFSGITVTKILGVTVLAFTRSKIFEIYYFRVWVALVVFAASHALVFLPVALSLGG 1241
[172][TOP]
>UniRef100_A5E1Z8 Putative uncharacterized protein n=1 Tax=Lodderomyces elongisporus
RepID=A5E1Z8_LODEL
Length = 1191
Score = 72.0 bits (175), Expect = 2e-11
Identities = 29/76 (38%), Positives = 54/76 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G S+ GIT+TKL+G+ +L F+R+++F +YYF+M+ +L+++ +H LV LP++LS FG
Sbjct: 1095 VGGSIIGGITITKLIGITILAFTRSKIFEVYYFRMWFALIVIAAVHSLVLLPILLSYFGD 1154
Query: 327 PSRCTIIEQEENRSST 280
++ I + + S+
Sbjct: 1155 LNKLNTIVYDGGQFSS 1170
[173][TOP]
>UniRef100_A3GGU6 Predicted protein n=1 Tax=Pichia stipitis RepID=A3GGU6_PICST
Length = 1268
Score = 72.0 bits (175), Expect = 2e-11
Identities = 31/73 (42%), Positives = 51/73 (69%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GITLTK++G+ VL F+R+++F +YYF+M+ SL+ + +H L LP++LS FG
Sbjct: 1165 VGGSVLGGITLTKIIGMFVLAFTRSKIFEVYYFRMWFSLIFIAAVHALCLLPILLSYFGD 1224
Query: 327 PSRCTIIEQEENR 289
+ T +E++
Sbjct: 1225 DHKTTSRISDESQ 1237
[174][TOP]
>UniRef100_A0MJA7 Niemann-Pick C1-like 1 protein n=1 Tax=Oryctolagus cuniculus
RepID=A0MJA7_RABIT
Length = 1325
Score = 71.6 bits (174), Expect = 3e-11
Identities = 30/78 (38%), Positives = 53/78 (67%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G+++L ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1207 MGSAVFAGVAMTNLPGILILGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYLGP 1266
Query: 327 PSRCTIIEQEENRSSTSS 274
++ E R+ ++
Sbjct: 1267 DVNPALVALERTRAQEAA 1284
[175][TOP]
>UniRef100_UPI0001A2D2B7 Novel protein similar to human and mouse intersectin 2 (ITSN2) n=1
Tax=Danio rerio RepID=UPI0001A2D2B7
Length = 1260
Score = 71.2 bits (173), Expect = 4e-11
Identities = 29/60 (48%), Positives = 47/60 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL F++ ++ I++F++ L + LLG HGL+FLPV+LS FGP
Sbjct: 1186 MGSAVFAGVAMTNLPGIVVLAFAKAQLIQIFFFRLNLVITLLGMAHGLIFLPVLLSYFGP 1245
[176][TOP]
>UniRef100_Q23E28 Patched family protein n=1 Tax=Tetrahymena thermophila SB210
RepID=Q23E28_TETTH
Length = 1207
Score = 71.2 bits (173), Expect = 4e-11
Identities = 34/77 (44%), Positives = 51/77 (66%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG+++ GI TK +GVIVL F+ +E+F IYYF+MY++++ LG GL+FLP VL GP
Sbjct: 1095 MGSNILVGIASTKFIGVIVLGFASSEMFRIYYFRMYMAIIFLGVFQGLMFLPTVLYYIGP 1154
Query: 327 PSRCTIIEQEENRSSTS 277
++ E ++S S
Sbjct: 1155 VTKGRTSESFIHKSDIS 1171
[177][TOP]
>UniRef100_C7GV50 Ncr1p n=1 Tax=Saccharomyces cerevisiae JAY291 RepID=C7GV50_YEAS2
Length = 1170
Score = 71.2 bits (173), Expect = 4e-11
Identities = 34/72 (47%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GITLTK +GV VL F+++++F ++YF+M+ +L+++ LH L+FLP +LS+FG
Sbjct: 1099 IGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGG 1158
Query: 327 PS-RCTIIEQEE 295
S R IE E+
Sbjct: 1159 ESYRDDSIEAED 1170
[178][TOP]
>UniRef100_B0CUV0 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
RepID=B0CUV0_LACBS
Length = 1341
Score = 71.2 bits (173), Expect = 4e-11
Identities = 34/59 (57%), Positives = 46/59 (77%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV SGIT TKL+G+ VL +R+ + IYYF+M+L+L++ G LHGLV LPVVL+I G
Sbjct: 1246 IGPSVLSGITFTKLIGMSVLALTRSRLLEIYYFRMWLTLIISGALHGLVLLPVVLNIAG 1304
[179][TOP]
>UniRef100_A6ZWP0 Niemann-Pick type C-related protein n=1 Tax=Saccharomyces cerevisiae
YJM789 RepID=A6ZWP0_YEAS7
Length = 1170
Score = 71.2 bits (173), Expect = 4e-11
Identities = 34/72 (47%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GITLTK +GV VL F+++++F ++YF+M+ +L+++ LH L+FLP +LS+FG
Sbjct: 1099 IGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGG 1158
Query: 327 PS-RCTIIEQEE 295
S R IE E+
Sbjct: 1159 ESYRDDSIEAED 1170
[180][TOP]
>UniRef100_Q12200 Niemann-Pick type C-related protein 1 n=2 Tax=Saccharomyces
cerevisiae RepID=NPC1_YEAST
Length = 1170
Score = 71.2 bits (173), Expect = 4e-11
Identities = 34/72 (47%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GITLTK +GV VL F+++++F ++YF+M+ +L+++ LH L+FLP +LS+FG
Sbjct: 1099 IGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGG 1158
Query: 327 PS-RCTIIEQEE 295
S R IE E+
Sbjct: 1159 ESYRDDSIEAED 1170
[181][TOP]
>UniRef100_A3KMG9 Npc1l1 protein (Fragment) n=1 Tax=Mus musculus RepID=A3KMG9_MOUSE
Length = 1332
Score = 70.9 bits (172), Expect = 5e-11
Identities = 30/71 (42%), Positives = 51/71 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T G+++L F++ ++ I++F++ L + LLG LHGLVFLPVVLS GP
Sbjct: 1208 MGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGP 1267
Query: 327 PSRCTIIEQEE 295
++ +E+
Sbjct: 1268 DVNQALVLEEK 1278
[182][TOP]
>UniRef100_A0CEP2 Chromosome undetermined scaffold_172, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CEP2_PARTE
Length = 912
Score = 70.9 bits (172), Expect = 5e-11
Identities = 32/60 (53%), Positives = 44/60 (73%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG SVF GI TK +GV VL F+ + +F +YYF+MY+ +V+LG +GLV LP+ L +FGP
Sbjct: 819 MGTSVFVGIACTKFIGVAVLGFAPSTLFKLYYFRMYILMVVLGAFNGLVLLPIFLGLFGP 878
[183][TOP]
>UniRef100_A0CA55 Chromosome undetermined scaffold_160, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0CA55_PARTE
Length = 903
Score = 70.9 bits (172), Expect = 5e-11
Identities = 32/60 (53%), Positives = 44/60 (73%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG SVF GI TK +GV VL F+ + +F +YYF+MY+ +V+LG +GLV LP+ L +FGP
Sbjct: 812 MGTSVFVGIACTKFIGVAVLGFAPSTLFKLYYFRMYILMVVLGAFNGLVLLPIFLGLFGP 871
[184][TOP]
>UniRef100_C8ZJ20 Ncr1p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8ZJ20_YEAST
Length = 1170
Score = 70.9 bits (172), Expect = 5e-11
Identities = 34/72 (47%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GITLTK +GV VL F+++++F ++YF+M+ +L+++ LH L+FLP +LS+FG
Sbjct: 1099 IGESVVKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGG 1158
Query: 327 PS-RCTIIEQEE 295
S R IE E+
Sbjct: 1159 ESYRDDSIEAED 1170
[185][TOP]
>UniRef100_Q6T3U4 Niemann-Pick C1-like protein 1 n=1 Tax=Mus musculus RepID=NPCL1_MOUSE
Length = 1333
Score = 70.9 bits (172), Expect = 5e-11
Identities = 30/71 (42%), Positives = 51/71 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T G+++L F++ ++ I++F++ L + LLG LHGLVFLPVVLS GP
Sbjct: 1209 MGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGP 1268
Query: 327 PSRCTIIEQEE 295
++ +E+
Sbjct: 1269 DVNQALVLEEK 1279
[186][TOP]
>UniRef100_A0MJA8 Niemann-Pick C1-like 1 protein n=1 Tax=Mesocricetus auratus
RepID=A0MJA8_MESAU
Length = 1328
Score = 70.5 bits (171), Expect = 6e-11
Identities = 30/71 (42%), Positives = 51/71 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T G+++L F++ ++ I++F++ L + LLG LHGLVFLPVVLS GP
Sbjct: 1209 MGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGP 1268
Query: 327 PSRCTIIEQEE 295
++ +E+
Sbjct: 1269 DVNPELVLEEK 1279
[187][TOP]
>UniRef100_C4M8X7 Niemann-Pick C1 protein, putative n=1 Tax=Entamoeba histolytica
HM-1:IMSS RepID=C4M8X7_ENTHI
Length = 1339
Score = 70.1 bits (170), Expect = 8e-11
Identities = 33/57 (57%), Positives = 43/57 (75%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSI 337
MG +VF GITLTK +GVIVL S +FVIYYF+MY +++ G HGL FLP++LS+
Sbjct: 1249 MGNNVFVGITLTKFLGVIVLSLSSGLIFVIYYFRMYFMMLIFGASHGLFFLPILLSL 1305
[188][TOP]
>UniRef100_B0E9R8 Niemann-Pick C1 protein, putative n=1 Tax=Entamoeba dispar SAW760
RepID=B0E9R8_ENTDI
Length = 1320
Score = 70.1 bits (170), Expect = 8e-11
Identities = 33/57 (57%), Positives = 43/57 (75%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSI 337
MG +VF GITLTK +GVIVL S +FVIYYF+MY +++ G HGL FLP++LS+
Sbjct: 1230 MGNNVFVGITLTKFLGVIVLSLSSGLIFVIYYFRMYFMMLIFGASHGLFFLPILLSL 1286
[189][TOP]
>UniRef100_B8PP27 Predicted protein (Fragment) n=1 Tax=Postia placenta Mad-698-R
RepID=B8PP27_POSPM
Length = 104
Score = 70.1 bits (170), Expect = 8e-11
Identities = 33/59 (55%), Positives = 45/59 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV SGIT TKL+G+ VL +R+ IYYF+M+++L++ G LHGLV LPVVLS+ G
Sbjct: 46 VGPSVLSGITFTKLIGMCVLALTRSRFLEIYYFRMWMTLIVSGALHGLVLLPVVLSLAG 104
[190][TOP]
>UniRef100_UPI00003BD942 hypothetical protein DEHA0D05335g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BD942
Length = 1264
Score = 69.7 bits (169), Expect = 1e-10
Identities = 29/59 (49%), Positives = 45/59 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV GITLTK +G+ VL F+++++F +YYF+M+L+LV + +H L LP++LS FG
Sbjct: 1181 VGGSVLGGITLTKFIGISVLAFTKSKIFEVYYFRMWLALVFIAAIHALCLLPILLSYFG 1239
[191][TOP]
>UniRef100_Q66NS0 Patched (Fragment) n=1 Tax=Ciona intestinalis RepID=Q66NS0_CIOIN
Length = 371
Score = 69.7 bits (169), Expect = 1e-10
Identities = 31/53 (58%), Positives = 44/53 (83%)
Frame = -1
Query: 498 SVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
SV SGIT TK VG+++L S++++F ++YF+MYL +V+LG HGLVFLPV+LS
Sbjct: 317 SVLSGITFTKFVGIVILASSKSQIFKVFYFRMYLCVVVLGAGHGLVFLPVLLS 369
[192][TOP]
>UniRef100_A0BF69 Chromosome undetermined scaffold_103, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0BF69_PARTE
Length = 912
Score = 69.7 bits (169), Expect = 1e-10
Identities = 32/62 (51%), Positives = 44/62 (70%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG SVF GI TK +GV VL F+ + +F +YYF+MY+ +V+LG +GLV LP+ L + GP
Sbjct: 819 MGTSVFVGIACTKFIGVAVLGFAPSTLFKLYYFRMYILMVILGAFNGLVLLPIFLGLVGP 878
Query: 327 PS 322
S
Sbjct: 879 QS 880
[193][TOP]
>UniRef100_Q6FKT2 Similar to uniprot|Q12200 Saccharomyces cerevisiae YPL006w n=1
Tax=Candida glabrata RepID=Q6FKT2_CANGA
Length = 1193
Score = 69.7 bits (169), Expect = 1e-10
Identities = 30/62 (48%), Positives = 47/62 (75%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G +VF+GITLTK +GV V+ F+++++F +YYF+M+ SL+ L +H LVFLP +L+ G
Sbjct: 1123 IGETVFNGITLTKFIGVTVIAFAQSKIFEVYYFRMWFSLICLASVHALVFLPALLTTLGG 1182
Query: 327 PS 322
S
Sbjct: 1183 KS 1184
[194][TOP]
>UniRef100_Q6BT03 DEHA2D04620p n=1 Tax=Debaryomyces hansenii RepID=Q6BT03_DEBHA
Length = 1264
Score = 69.7 bits (169), Expect = 1e-10
Identities = 29/59 (49%), Positives = 45/59 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SV GITLTK +G+ VL F+++++F +YYF+M+L+LV + +H L LP++LS FG
Sbjct: 1181 VGGSVLGGITLTKFIGISVLAFTKSKIFEVYYFRMWLALVFIAAIHALCLLPILLSYFG 1239
[195][TOP]
>UniRef100_UPI00016E1F22 UPI00016E1F22 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E1F22
Length = 1297
Score = 69.3 bits (168), Expect = 1e-10
Identities = 29/59 (49%), Positives = 47/59 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG++VF+G+ +T L G++VL F++ ++ I++F++ L + LLG +HGLVFLPV+LS FG
Sbjct: 1239 MGSAVFAGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGLVHGLVFLPVLLSYFG 1297
[196][TOP]
>UniRef100_A0MJA4 Niemann-Pick C1-like 1 protein n=1 Tax=Canis lupus familiaris
RepID=A0MJA4_CANFA
Length = 1325
Score = 68.9 bits (167), Expect = 2e-10
Identities = 29/67 (43%), Positives = 48/67 (71%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + +LG LHGLVFLPVVLS GP
Sbjct: 1208 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITVLGLLHGLVFLPVVLSYLGP 1267
Query: 327 PSRCTII 307
++
Sbjct: 1268 DINAALV 1274
[197][TOP]
>UniRef100_A0MJA5 Niemann-Pick C1-like 1 protein n=2 Tax=Macaca RepID=A0MJA5_MACMU
Length = 1332
Score = 68.6 bits (166), Expect = 2e-10
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1208 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1267
[198][TOP]
>UniRef100_Q17RV5 NPC1-like 1 protein n=2 Tax=Homo sapiens RepID=Q17RV5_HUMAN
Length = 1332
Score = 68.6 bits (166), Expect = 2e-10
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1208 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1267
[199][TOP]
>UniRef100_B7ZLE6 NPC1L1 protein n=1 Tax=Homo sapiens RepID=B7ZLE6_HUMAN
Length = 1286
Score = 68.6 bits (166), Expect = 2e-10
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1162 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1221
[200][TOP]
>UniRef100_A8MSP5 NPC1 (Niemann-Pick disease, type C1, gene)-like 1, isoform CRA_a n=1
Tax=Homo sapiens RepID=A8MSP5_HUMAN
Length = 1359
Score = 68.6 bits (166), Expect = 2e-10
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1235 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1294
[201][TOP]
>UniRef100_Q9UHC9 Niemann-Pick C1-like protein 1 n=1 Tax=Homo sapiens RepID=NPCL1_HUMAN
Length = 1359
Score = 68.6 bits (166), Expect = 2e-10
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1235 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGP 1294
[202][TOP]
>UniRef100_UPI000151B5B2 hypothetical protein PGUG_04987 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151B5B2
Length = 1248
Score = 68.2 bits (165), Expect = 3e-10
Identities = 28/55 (50%), Positives = 46/55 (83%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
G +V SGIT+TKL+G++VL F+++++F +YYF+M+L+LV++ +H L LPV+LS
Sbjct: 1167 GGTVLSGITITKLIGILVLAFTKSKIFEVYYFRMWLALVVIAAVHSLCLLPVLLS 1221
[203][TOP]
>UniRef100_Q4T749 Chromosome undetermined SCAF8317, whole genome shotgun sequence.
(Fragment) n=1 Tax=Tetraodon nigroviridis
RepID=Q4T749_TETNG
Length = 1132
Score = 68.2 bits (165), Expect = 3e-10
Identities = 28/59 (47%), Positives = 46/59 (77%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
MG++VF+G+ +T L G++VL F++ ++ I++F++ L + LLG HGL+FLPV+LS FG
Sbjct: 1066 MGSAVFAGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGMAHGLIFLPVLLSYFG 1124
[204][TOP]
>UniRef100_Q6CIF2 KLLA0F27137p n=1 Tax=Kluyveromyces lactis RepID=Q6CIF2_KLULA
Length = 1177
Score = 68.2 bits (165), Expect = 3e-10
Identities = 31/72 (43%), Positives = 52/72 (72%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SV GIT+TK++G+ VL +++++F ++YF+M+ SL+ + LH L+FLPV+LS+ G
Sbjct: 1104 IGGSVLKGITMTKIIGISVLALTQSKIFQVFYFRMWASLIFVASLHALIFLPVLLSMIG- 1162
Query: 327 PSRCTIIEQEEN 292
+C IE + N
Sbjct: 1163 -GKC-FIESKSN 1172
[205][TOP]
>UniRef100_UPI0001795FBF PREDICTED: similar to NPC1 (Niemann-Pick disease, type C1, gene)-like
1 n=1 Tax=Equus caballus RepID=UPI0001795FBF
Length = 1329
Score = 67.0 bits (162), Expect = 7e-10
Identities = 28/78 (35%), Positives = 52/78 (66%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G++VF+G+ +T L G++VL + ++ I++F++ L + LLG LHGLVFLPV+LS GP
Sbjct: 1207 VGSAVFAGVAMTNLPGILVLGLASAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYLGP 1266
Query: 327 PSRCTIIEQEENRSSTSS 274
++ +++ ++
Sbjct: 1267 EVNPALVLEQKRAEEAAA 1284
[206][TOP]
>UniRef100_Q6CBA1 YALI0C20757p n=1 Tax=Yarrowia lipolytica RepID=Q6CBA1_YARLI
Length = 1239
Score = 67.0 bits (162), Expect = 7e-10
Identities = 28/59 (47%), Positives = 45/59 (76%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G SVF GI +TK +GV VL F+R+++F +YYF+++L+LV++ H L+ LPV+L+ G
Sbjct: 1148 VGGSVFGGIAMTKFLGVFVLAFTRSKIFEVYYFRVWLALVIVATTHSLILLPVLLTYIG 1206
[207][TOP]
>UniRef100_A5DNY6 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DNY6_PICGU
Length = 1248
Score = 66.6 bits (161), Expect = 9e-10
Identities = 28/55 (50%), Positives = 45/55 (81%)
Frame = -1
Query: 504 GASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
G +V SGIT+TKL+G+ VL F+++++F +YYF+M+L+LV++ +H L LPV+LS
Sbjct: 1167 GGTVLSGITITKLIGISVLAFTKSKIFEVYYFRMWLALVVIAAVHSLCLLPVLLS 1221
[208][TOP]
>UniRef100_UPI000175FC51 PREDICTED: similar to Niemann-Pick C1-like protein 1, partial n=1
Tax=Danio rerio RepID=UPI000175FC51
Length = 157
Score = 66.2 bits (160), Expect = 1e-09
Identities = 27/56 (48%), Positives = 43/56 (76%)
Frame = -1
Query: 495 VFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
VF+G+ +T L G++VL F++ ++ I++F++ L + LLG HGL+FLPV+LS FGP
Sbjct: 1 VFAGVAMTNLPGIVVLAFAKAQLIQIFFFRLNLVITLLGMAHGLIFLPVLLSYFGP 56
[209][TOP]
>UniRef100_Q0U4X8 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U4X8_PHANO
Length = 1277
Score = 65.9 bits (159), Expect = 2e-09
Identities = 29/59 (49%), Positives = 46/59 (77%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+ +SV SGIT+TK++GV L F+R+++F IYYF+++++LVL H L+ LPV+LS+ G
Sbjct: 1182 VASSVISGITITKVLGVATLAFTRSKIFEIYYFRVWVALVLWASTHALILLPVLLSLLG 1240
[210][TOP]
>UniRef100_B2W9M2 Niemann-Pick C1 protein n=1 Tax=Pyrenophora tritici-repentis
Pt-1C-BFP RepID=B2W9M2_PYRTR
Length = 1265
Score = 65.9 bits (159), Expect = 2e-09
Identities = 29/59 (49%), Positives = 47/59 (79%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+ +SV SGIT+TK++GV VL F+R+++F +YYF+++++LVL H L+ LPV+LS+ G
Sbjct: 1171 VASSVVSGITITKILGVGVLAFTRSKIFEVYYFRVWVALVLWASTHALILLPVLLSLIG 1229
[211][TOP]
>UniRef100_Q642F9 Cdig2 protein (Fragment) n=1 Tax=Rattus norvegicus RepID=Q642F9_RAT
Length = 73
Score = 65.1 bits (157), Expect = 3e-09
Identities = 27/48 (56%), Positives = 40/48 (83%)
Frame = -1
Query: 471 KLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
K G++VL F+++++F I+YF+MYL++VLLG HGL+FLPV+LS GP
Sbjct: 1 KFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 48
[212][TOP]
>UniRef100_C5DBG1 KLTH0A02332p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DBG1_LACTC
Length = 1179
Score = 64.7 bits (156), Expect = 3e-09
Identities = 28/62 (45%), Positives = 42/62 (67%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
+G SVF GITLTK +GV +L F+ +++F ++YF+M+ L++ H L FLP LS+ G
Sbjct: 1108 VGGSVFQGITLTKFIGVSILAFTHSKIFQVFYFRMWFILIIASCAHALFFLPAALSLVGG 1167
Query: 327 PS 322
S
Sbjct: 1168 KS 1169
[213][TOP]
>UniRef100_UPI0000D9AA97 PREDICTED: similar to NPC1-like 1, partial n=1 Tax=Macaca mulatta
RepID=UPI0000D9AA97
Length = 92
Score = 64.3 bits (155), Expect = 4e-09
Identities = 27/56 (48%), Positives = 44/56 (78%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLS 340
MG++VF+G+ +T L G++VL ++ ++ I++F++ L + LLG LHGLVFLPV+LS
Sbjct: 35 MGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILS 90
[214][TOP]
>UniRef100_UPI000034F451 patched family protein n=1 Tax=Arabidopsis thaliana
RepID=UPI000034F451
Length = 1272
Score = 58.9 bits (141), Expect = 2e-07
Identities = 26/62 (41%), Positives = 35/62 (56%)
Frame = -3
Query: 505 GCFSLQWYHTNKIGWSYCSLLLKNRSFCDLLLSDVLVVSTSWFSARTCFLAGGIKHLWST 326
G FS QW + ++ W C+ LK RS C +LL DV S S F R C G ++H+WS+
Sbjct: 1181 GSFSFQWNYIDETSWGDCARFLKIRSLCGVLLQDVFGTSPSRFLTRPCIFTGVLEHVWSS 1240
Query: 325 FK 320
K
Sbjct: 1241 SK 1242
[215][TOP]
>UniRef100_Q4PE83 Putative uncharacterized protein n=1 Tax=Ustilago maydis
RepID=Q4PE83_USTMA
Length = 1489
Score = 58.9 bits (141), Expect = 2e-07
Identities = 27/59 (45%), Positives = 44/59 (74%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFG 331
+G++V +GI TKL+GV VL F+++++ +YY + +L L++ G LHGL+ LPV+LS G
Sbjct: 1386 VGSAVVNGIFSTKLIGVGVLIFTKSDLLKLYYAKTWLCLIVGGLLHGLILLPVLLSWLG 1444
[216][TOP]
>UniRef100_UPI0001792008 PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA n=1
Tax=Acyrthosiphon pisum RepID=UPI0001792008
Length = 1117
Score = 57.8 bits (138), Expect = 4e-07
Identities = 29/61 (47%), Positives = 42/61 (68%)
Frame = -1
Query: 477 LTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPPSRCTIIEQE 298
LTK G+ VL F+ T VF I+Y++MY+ +V++ LH LVFLPV+LS G S ++EQ
Sbjct: 1040 LTKFAGLAVLGFANTPVFKIFYYRMYMGIVIIAALHSLVFLPVLLSYKG--SYHVLVEQT 1097
Query: 297 E 295
+
Sbjct: 1098 D 1098
[217][TOP]
>UniRef100_B7P4P1 Patched-2 protein, putative (Fragment) n=1 Tax=Ixodes scapularis
RepID=B7P4P1_IXOSC
Length = 1172
Score = 57.0 bits (136), Expect = 7e-07
Identities = 31/78 (39%), Positives = 50/78 (64%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A V G T L+GV++L FS + V ++F + +L+++G L+GL+FLP++LS+ GP
Sbjct: 1044 MFAPVVHGAVST-LLGVLMLAFSEFDFIVRHFFYVLSALIVIGLLNGLLFLPIILSLVGP 1102
Query: 327 PSRCTIIEQEENRSSTSS 274
P + + + NR ST S
Sbjct: 1103 PGE-VVPKGDSNRISTPS 1119
[218][TOP]
>UniRef100_UPI00017B10BC UPI00017B10BC related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B10BC
Length = 1362
Score = 55.1 bits (131), Expect = 3e-06
Identities = 29/65 (44%), Positives = 42/65 (64%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A VF G ++ L+GV++L S E + Y+F + L +LG L+GLV LPV+LS+ GP
Sbjct: 1065 MFAPVFDG-AISTLLGVLMLAGSEFEFIIRYFFAVLAILTVLGILNGLVLLPVLLSVLGP 1123
Query: 327 PSRCT 313
P+ T
Sbjct: 1124 PAEFT 1128
[219][TOP]
>UniRef100_UPI00017B10BB UPI00017B10BB related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B10BB
Length = 1327
Score = 55.1 bits (131), Expect = 3e-06
Identities = 29/65 (44%), Positives = 42/65 (64%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A VF G ++ L+GV++L S E + Y+F + L +LG L+GLV LPV+LS+ GP
Sbjct: 1072 MFAPVFDG-AISTLLGVLMLAGSEFEFIIRYFFAVLAILTVLGILNGLVLLPVLLSVLGP 1130
Query: 327 PSRCT 313
P+ T
Sbjct: 1131 PAEFT 1135
[220][TOP]
>UniRef100_UPI00016E13F1 UPI00016E13F1 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E13F1
Length = 1322
Score = 55.1 bits (131), Expect = 3e-06
Identities = 30/62 (48%), Positives = 41/62 (66%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A VF G T L+GV++L S E + Y+F + + L +LG L+GLV LPV+LSI GP
Sbjct: 1062 MFAPVFDGAVST-LLGVLMLAGSEFEFIIWYFFAVLVILTMLGVLNGLVLLPVLLSIMGP 1120
Query: 327 PS 322
P+
Sbjct: 1121 PA 1122
[221][TOP]
>UniRef100_UPI00016E13F0 UPI00016E13F0 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E13F0
Length = 1406
Score = 55.1 bits (131), Expect = 3e-06
Identities = 30/62 (48%), Positives = 41/62 (66%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A VF G T L+GV++L S E + Y+F + + L +LG L+GLV LPV+LSI GP
Sbjct: 1097 MFAPVFDGAVST-LLGVLMLAGSEFEFIIWYFFAVLVILTMLGVLNGLVLLPVLLSIMGP 1155
Query: 327 PS 322
P+
Sbjct: 1156 PA 1157
[222][TOP]
>UniRef100_A8QG51 Patched family protein n=1 Tax=Brugia malayi RepID=A8QG51_BRUMA
Length = 1422
Score = 55.1 bits (131), Expect = 3e-06
Identities = 23/60 (38%), Positives = 42/60 (70%)
Frame = -1
Query: 477 LTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPPSRCTIIEQE 298
L+ L+G+++L FS + V Y+F + +L+L+G ++GLV LPV+LS+ GPP + +++
Sbjct: 1208 LSTLLGILMLAFSEFDFIVKYFFIVLSALILIGLINGLVLLPVLLSLIGPPCEIRLFDEK 1267
[223][TOP]
>UniRef100_Q007R7 Patched protein n=1 Tax=Lytechinus variegatus RepID=Q007R7_LYTVA
Length = 1416
Score = 54.3 bits (129), Expect = 5e-06
Identities = 27/58 (46%), Positives = 41/58 (70%)
Frame = -1
Query: 501 ASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
A V G T L+GV++L + + V Y+F ++L+L++LG L+GLV LPV+LS+FGP
Sbjct: 1121 APVLDGAVST-LLGVVMLAGAEFDFIVSYFFYVFLALIILGVLNGLVLLPVLLSLFGP 1177
[224][TOP]
>UniRef100_UPI000186E03F patched 1, putative n=1 Tax=Pediculus humanus corporis
RepID=UPI000186E03F
Length = 1320
Score = 53.9 bits (128), Expect = 6e-06
Identities = 27/67 (40%), Positives = 42/67 (62%)
Frame = -1
Query: 477 LTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPPSRCTIIEQE 298
+T L+G+ +L FS V Y+F + L+L+ +G L+GLVF PV+LS+ GP + IE
Sbjct: 1090 VTTLLGIAMLSFSEFGFIVRYFFYVLLALIAVGLLNGLVFFPVLLSLIGPAAEVVGIEHL 1149
Query: 297 ENRSSTS 277
+ S+ S
Sbjct: 1150 DRISTPS 1156
[225][TOP]
>UniRef100_Q4RVD6 Chromosome 15 SCAF14992, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4RVD6_TETNG
Length = 1197
Score = 53.9 bits (128), Expect = 6e-06
Identities = 28/62 (45%), Positives = 41/62 (66%)
Frame = -1
Query: 507 MGASVFSGITLTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGP 328
M A VF G ++ L+GV++L S E + Y+F + L +LG L+GLV LPV+LS+ GP
Sbjct: 1136 MFAPVFDG-AISTLLGVLMLAGSEFEFIIRYFFAVLAILTVLGILNGLVLLPVLLSVLGP 1194
Query: 327 PS 322
P+
Sbjct: 1195 PA 1196
[226][TOP]
>UniRef100_A5APM6 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5APM6_VITVI
Length = 1050
Score = 53.9 bits (128), Expect = 6e-06
Identities = 24/27 (88%), Positives = 26/27 (96%)
Frame = -1
Query: 429 VFVIYYFQMYLSLVLLGFLHGLVFLPV 349
VF +YYFQMYL+LVLLGFLHGLVFLPV
Sbjct: 1002 VFQVYYFQMYLALVLLGFLHGLVFLPV 1028
[227][TOP]
>UniRef100_UPI000180C4FF PREDICTED: patched receptor n=1 Tax=Ciona intestinalis
RepID=UPI000180C4FF
Length = 1452
Score = 53.5 bits (127), Expect = 8e-06
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = -1
Query: 477 LTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPPSRCTII 307
++ L+GV++L S + + Y+FQ+ L+LLG L+GLV LPVVLS GPP T I
Sbjct: 1120 VSTLLGVVMLAGSEFDFIIKYFFQVLGILILLGVLNGLVLLPVVLSFIGPPPEVTPI 1176
[228][TOP]
>UniRef100_Q4H2Z6 Patched receptor (Fragment) n=1 Tax=Ciona intestinalis
RepID=Q4H2Z6_CIOIN
Length = 976
Score = 53.5 bits (127), Expect = 8e-06
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = -1
Query: 477 LTKLVGVIVLYFSRTEVFVIYYFQMYLSLVLLGFLHGLVFLPVVLSIFGPPSRCTII 307
++ L+GV++L S + + Y+FQ+ L+LLG L+GLV LPVVLS GPP T I
Sbjct: 644 VSTLLGVVMLAGSEFDFIIKYFFQVLGILILLGVLNGLVLLPVVLSFIGPPPEVTPI 700