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[1][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 218 bits (556), Expect = 1e-55
Identities = 106/124 (85%), Positives = 114/124 (91%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+IEKIH AA++DPN+VVFSFEFFPPKTEDGV NL ERMDRMV H+PSFCDITW AGG+
Sbjct: 1 MKIIEKIH-AASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGT 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA KMQN V VETMMHLTCTNMPVEKID AL TIKSNGLQNVLALRGDPPHGQ
Sbjct: 60 TADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQ 119
Query: 437 DKFV 448
DKFV
Sbjct: 120 DKFV 123
[2][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 216 bits (550), Expect = 6e-55
Identities = 109/136 (80%), Positives = 114/136 (83%), Gaps = 12/136 (8%)
Frame = +2
Query: 77 MKVIEKIHEAAA------------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSP 220
MKVI+KI EAA S NKVVFSFEFFPPKTEDGV NL ERMDRMVAH+P
Sbjct: 1 MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP 60
Query: 221 SFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQN 400
SFCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QN
Sbjct: 61 SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN 120
Query: 401 VLALRGDPPHGQDKFV 448
VLALRGDPPHGQDKFV
Sbjct: 121 VLALRGDPPHGQDKFV 136
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 214 bits (544), Expect = 3e-54
Identities = 107/133 (80%), Positives = 114/133 (85%), Gaps = 9/133 (6%)
Frame = +2
Query: 77 MKVIEKIHEAAA---------SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFC 229
MKVI+KI AAA S NKVVFSFEFFPPKT+DGV NL ERMDRMV+H+PSFC
Sbjct: 1 MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC 60
Query: 230 DITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLA 409
DITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID ALETIKSNG+QNVLA
Sbjct: 61 DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA 120
Query: 410 LRGDPPHGQDKFV 448
LRGDPPHGQDKFV
Sbjct: 121 LRGDPPHGQDKFV 133
[4][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 212 bits (540), Expect = 9e-54
Identities = 103/124 (83%), Positives = 112/124 (90%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 437 DKFV 448
DKFV
Sbjct: 120 DKFV 123
[5][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 212 bits (540), Expect = 9e-54
Identities = 103/124 (83%), Positives = 112/124 (90%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 437 DKFV 448
DKFV
Sbjct: 120 DKFV 123
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 212 bits (540), Expect = 9e-54
Identities = 103/124 (83%), Positives = 112/124 (90%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI +AA + KVVFSFEFFPPKTEDGV NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIRDAATEE-GKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+I+ KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+QNVLALRGDPPHGQ
Sbjct: 60 TADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQ 119
Query: 437 DKFV 448
DKFV
Sbjct: 120 DKFV 123
[7][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 209 bits (532), Expect = 8e-53
Identities = 102/124 (82%), Positives = 111/124 (89%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 209 bits (532), Expect = 8e-53
Identities = 102/124 (82%), Positives = 111/124 (89%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI EAAA + VFSFE+FPPKTE+G+ NL ERMDRMVAH P+FCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAAD--GRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKIDDAL TIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[9][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 209 bits (531), Expect = 1e-52
Identities = 102/124 (82%), Positives = 110/124 (88%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI EAA + + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQEAAGN--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[10][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 207 bits (527), Expect = 3e-52
Identities = 102/124 (82%), Positives = 109/124 (87%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI EAA + FSFE+FPPKTE+GV NL ERMDRMVAH PSFCDITWGAGGS
Sbjct: 1 MKVIEKILEAAGD--GRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN V VETMMHLTCTNMPVEKID ALETIKSNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[11][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 205 bits (521), Expect = 1e-51
Identities = 104/137 (75%), Positives = 114/137 (83%), Gaps = 13/137 (9%)
Frame = +2
Query: 77 MKVIEKIHEA------------AASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS 217
MKVI+KI + A SD N KVVFSFEFFPPKTEDGV NL +RMDRMV+H+
Sbjct: 1 MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN 60
Query: 218 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 397
P+FCDITWGAGGSTAD+TLDIA KMQN + VETMMHLTCTNMPVEKID AL+TIKSNG+Q
Sbjct: 61 PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ 120
Query: 398 NVLALRGDPPHGQDKFV 448
NVLALRGDPPHGQDKFV
Sbjct: 121 NVLALRGDPPHGQDKFV 137
[12][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 204 bits (520), Expect = 2e-51
Identities = 100/124 (80%), Positives = 108/124 (87%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVI+KI A D K FSFEFFPPKTEDGV NL ERMDRMVA+ P+FCDITWGAGGS
Sbjct: 1 MKVIDKIQSLA--DEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TLDIA +MQN V VE+MMHLTCTNMPVEKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[13][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 202 bits (515), Expect = 7e-51
Identities = 99/124 (79%), Positives = 107/124 (86%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVIEKI A KVVFSFEFFPPKTE+GV NL +RMDRMV H PSFCDITWGAGGS
Sbjct: 1 MKVIEKIQNAEKE--GKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TLDI+ KMQN + VE+MMHLTCTNMPVEKID AL TIK+NG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[14][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 197 bits (502), Expect = 2e-49
Identities = 92/124 (74%), Positives = 109/124 (87%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[15][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 197 bits (502), Expect = 2e-49
Identities = 92/124 (74%), Positives = 109/124 (87%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[16][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 197 bits (502), Expect = 2e-49
Identities = 92/124 (74%), Positives = 109/124 (87%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKV++KI + ++ + FSFEFFPPKTEDGV NL ERMDR+V++ P+FCDITWGAGGS
Sbjct: 1 MKVVDKIK--SVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TAD+TL+IA +MQN + VETMMHLTCTNMP+EKID ALETI+SNG+QNVLALRGDPPHGQ
Sbjct: 59 TADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[17][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 192 bits (487), Expect = 1e-47
Identities = 92/124 (74%), Positives = 105/124 (84%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T+ VTLDIA KMQN + VETMMHLTCTNM VE +D AL+++KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 192 bits (487), Expect = 1e-47
Identities = 91/124 (73%), Positives = 105/124 (84%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MKVI+KI+ A VVFSFEFFPPKTE+GV NL +RMDRMV H P+FCDITWGAGGS
Sbjct: 1 MKVIDKINNGLAG--GNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T+ +TLDIA KMQN + VETMMHLTCTNM VE +D+AL+ +KSNG+QN+LALRGDPPHGQ
Sbjct: 59 TSAITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPHGQ 118
Query: 437 DKFV 448
DKFV
Sbjct: 119 DKFV 122
[19][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 177 bits (448), Expect = 4e-43
Identities = 83/98 (84%), Positives = 90/98 (91%)
Frame = +2
Query: 155 PKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTC 334
P+ +GV NL ERMDRMVAH P+FCDITWGAGGSTADVTLDIA +MQN V VETMMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 335 TNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
TNMPVEKID+AL+TIKSNG+QNVLALRGDPPHGQDKFV
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFV 110
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 166 bits (421), Expect = 6e-40
Identities = 79/117 (67%), Positives = 93/117 (79%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I K+ E + FSFEFFPP+TE+GV NL ER+DRMVA+ P FCDITWGAGGS
Sbjct: 1 MKLIHKVEEKMKK--GETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
TADVTLDIA +MQN + VETMMHLTCTNMP EK++ AL +K G+QN+LALRGDPP
Sbjct: 59 TADVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPP 115
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 147 bits (372), Expect = 3e-34
Identities = 71/121 (58%), Positives = 92/121 (76%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+KI + S N +SFE+FPPKT +GV NL +R+ RM+ P F DITWGAGGS
Sbjct: 4 MKIIDKIQKKKES--NTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGGS 61
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T+ +TL+IA+K QN G+ETMMHLTCTNMPV +I AL+ KS G++N+LALRGDPP G+
Sbjct: 62 TSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNILALRGDPPRGE 121
Query: 437 D 439
+
Sbjct: 122 E 122
[22][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 143 bits (360), Expect = 7e-33
Identities = 67/123 (54%), Positives = 92/123 (74%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ +KI ++A +D K+ +SFE+FPP+T G+ NLL+R++RM A P F DITW AGG
Sbjct: 1 MKITQKIQQSANND--KIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL K +G +NVLALRGDPP G+
Sbjct: 59 TSDLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGK 118
Query: 437 DKF 445
D++
Sbjct: 119 DEW 121
[23][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 133 bits (335), Expect = 5e-30
Identities = 65/123 (52%), Positives = 86/123 (69%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + EK+ + A++ +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAAE--RVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ +G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[24][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 131 bits (330), Expect = 2e-29
Identities = 64/119 (53%), Positives = 83/119 (69%), Gaps = 2/119 (1%)
Frame = +2
Query: 77 MKVIEKIHEA--AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAG 250
MK+ EK+H+A ++ P FSFEFF PKT GV NL +RMDRM +P F DITW AG
Sbjct: 1 MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG 60
Query: 251 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
G ++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNILALRGDPP 119
[25][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 131 bits (329), Expect = 3e-29
Identities = 66/118 (55%), Positives = 83/118 (70%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
MK+ EK+ +A S+P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPP 118
[26][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 131 bits (329), Expect = 3e-29
Identities = 66/118 (55%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
MK+ EK+ +A S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+ALE +G QN+LALRGDPP
Sbjct: 61 RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPP 118
[27][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 130 bits (328), Expect = 4e-29
Identities = 62/122 (50%), Positives = 83/122 (68%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 259
K+ KI A A ++ +SFE+FPP+T G+ NL +R++RM P F DITW AGG T
Sbjct: 18 KITNKI--AKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRT 75
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+D+T + K + +G+ET MHLTCTNMP EKID AL+ K G +N+LALRGDPP GQ
Sbjct: 76 SDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPPAGQS 135
Query: 440 KF 445
++
Sbjct: 136 EW 137
[28][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 130 bits (327), Expect = 5e-29
Identities = 64/123 (52%), Positives = 85/123 (69%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHISEKLAQNEAA--GRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[29][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 129 bits (325), Expect = 8e-29
Identities = 67/120 (55%), Positives = 84/120 (70%), Gaps = 3/120 (2%)
Frame = +2
Query: 77 MKVIEKI---HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 247
MK+ EK+ H+AA S P FSFEFF PKT GV NL +RMDRM +P F DITW A
Sbjct: 1 MKISEKLDQAHKAAHSPP--ATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNA 58
Query: 248 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
GG ++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL+ +G QN+LALRGDPP
Sbjct: 59 GGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPP 118
[30][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 129 bits (325), Expect = 8e-29
Identities = 62/117 (52%), Positives = 80/117 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ EK+ A + FSFEFF PKT GV NL +RMDRM SP F DITW AGG
Sbjct: 1 MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR 60
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++++T ++ Q +G+ET MHLTCTNM +E ID+AL++ +G QN+LALRGDPP
Sbjct: 61 SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPP 117
[31][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 129 bits (324), Expect = 1e-28
Identities = 64/121 (52%), Positives = 82/121 (67%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M V +K+++ A +V SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHVKDKLYQNEAG--GQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MP+EK+D AL G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDK 118
Query: 437 D 439
+
Sbjct: 119 E 119
[32][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 129 bits (323), Expect = 1e-28
Identities = 64/121 (52%), Positives = 80/121 (66%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + EK+ + A K SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIREKLAKNEAE--GKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MPVEK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREK 118
Query: 437 D 439
+
Sbjct: 119 E 119
[33][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 129 bits (323), Expect = 1e-28
Identities = 64/118 (54%), Positives = 83/118 (70%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
MK+ +K+ +A +S +P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++ +T ++ Q+T+G+ET MHLTCTNM VE ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNILALRGDPP 118
[34][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 128 bits (322), Expect = 2e-28
Identities = 63/123 (51%), Positives = 85/123 (69%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M V +K+ E AA+ + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHVGQKLQEQAAT--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ + Q G+ET MHLTCT+MP E++D ALE + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQ 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[35][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 128 bits (322), Expect = 2e-28
Identities = 63/118 (53%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPP 118
[36][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 128 bits (321), Expect = 2e-28
Identities = 60/120 (50%), Positives = 83/120 (69%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 259
K+ +++ E +A V SFEFFPP+T+DGV +L+ R+ R P F D+TWGAGGST
Sbjct: 5 KISDRLQELSAKGEKFV--SFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGST 62
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+D+TLD+ +M G MHLTCTNMP EKID AL+ + G++N++ALRGDPP G++
Sbjct: 63 SDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPPAGEE 122
[37][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 127 bits (320), Expect = 3e-28
Identities = 63/118 (53%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEA-AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M++ EK+ +A + S P FSFEFF PKT GV NL +RMDRM +P F DITW AGG
Sbjct: 1 MRISEKLLQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
++ +T ++ Q+T+G+ET MHLTCTNM +E ID+AL +G QN+LALRGDPP
Sbjct: 61 RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPP 118
[38][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 127 bits (320), Expect = 3e-28
Identities = 62/123 (50%), Positives = 84/123 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[39][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 127 bits (320), Expect = 3e-28
Identities = 62/123 (50%), Positives = 84/123 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[40][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 127 bits (320), Expect = 3e-28
Identities = 59/111 (53%), Positives = 82/111 (73%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 286
AA P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 AALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 287 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
QN +G+ T++HLTCTN E ID+AL+ K +G++N+LALRGDPP ++
Sbjct: 69 TCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNILALRGDPPRAEE 119
[41][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 127 bits (319), Expect = 4e-28
Identities = 59/107 (55%), Positives = 79/107 (73%)
Frame = +2
Query: 119 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 298
P++ SFEFFPPKT+ G NLL R++RM A +P F ITWGAGGST++ +LD+A Q
Sbjct: 13 PDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTSEKSLDLAATCQK 72
Query: 299 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
VG+ T++HLTCTN E ID+AL K+NG++N+LALRGDPP ++
Sbjct: 73 EVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEE 119
[42][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 127 bits (319), Expect = 4e-28
Identities = 63/121 (52%), Positives = 81/121 (66%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + EK+ + A+ + SFEFFPPKT GV NL +RMDRM A PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDK 118
Query: 437 D 439
+
Sbjct: 119 E 119
[43][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 126 bits (317), Expect = 7e-28
Identities = 62/121 (51%), Positives = 81/121 (66%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + EK+ + A+ K+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKEKLAQNEAA--GKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+D+T ++ Q+ G+ET MHLTCT+MP E++D AL+ G N+LALRGDPP +
Sbjct: 59 LSDLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREK 118
Query: 437 D 439
+
Sbjct: 119 E 119
[44][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 126 bits (317), Expect = 7e-28
Identities = 64/125 (51%), Positives = 84/125 (67%), Gaps = 2/125 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
M++ EK+ S K FSFE+F PKT GV NL +RMDRM + P F D+TW AGG
Sbjct: 1 MRISEKLQNHR-SKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGG 59
Query: 254 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
+ +T D+ + Q+ +G+ET MHLTCTNMPV +IDDALE+ + +G QN+LALRGDPP
Sbjct: 60 GVLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPV 119
Query: 431 GQDKF 445
D +
Sbjct: 120 NSDSW 124
[45][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 126 bits (317), Expect = 7e-28
Identities = 58/103 (56%), Positives = 75/103 (72%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKW 121
[46][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 126 bits (317), Expect = 7e-28
Identities = 58/103 (56%), Positives = 75/103 (72%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+
Sbjct: 79 CMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEKW 121
[47][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 126 bits (317), Expect = 7e-28
Identities = 61/123 (49%), Positives = 84/123 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[48][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 126 bits (317), Expect = 7e-28
Identities = 61/123 (49%), Positives = 84/123 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ A A+ + SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG
Sbjct: 1 MHIKDKLAHAEAT--GRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ Q+ G+ET MHLTCT+MP EK+D A+++ G N+LALRGDPP +
Sbjct: 59 LSELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREK 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[49][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 126 bits (316), Expect = 9e-28
Identities = 60/104 (57%), Positives = 73/104 (70%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKW 121
[50][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 126 bits (316), Expect = 9e-28
Identities = 61/119 (51%), Positives = 82/119 (68%), Gaps = 2/119 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ +K+ + P+K FSFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG 60
Query: 254 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ ++ ++ Q+ +G+ET MHLTCTNMP+ +ID+ALE ++G QN+LALRGDPP
Sbjct: 61 GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPP 119
[51][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 126 bits (316), Expect = 9e-28
Identities = 64/122 (52%), Positives = 82/122 (67%), Gaps = 1/122 (0%)
Frame = +2
Query: 77 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M + +K+ H AA P+ SFEFFPPKT GV NL +RMDRM PSF DITWGAGG
Sbjct: 1 MHIKDKLAHSEAAGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGG 57
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL++ G N+LALRGDPP
Sbjct: 58 RLSDLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNILALRGDPPRE 117
Query: 434 QD 439
++
Sbjct: 118 KE 119
[52][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 126 bits (316), Expect = 9e-28
Identities = 58/103 (56%), Positives = 75/103 (72%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +++T ++ Q+ G+ET
Sbjct: 19 SFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLSELTCEMVNVAQSVYGLET 78
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
MHLTCT+MP EK+D AL++ G N+LALRGDPP ++K+
Sbjct: 79 CMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEKW 121
[53][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 126 bits (316), Expect = 9e-28
Identities = 61/123 (49%), Positives = 84/123 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ E S + SFE+FPPKT GV NL +RMDRM P+F D+TWGAGGS
Sbjct: 1 MHIGQKLQEQETS--GRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ + Q G+ET MHLTCT+MP E++D ALE+ + G N+LALRGDPP Q
Sbjct: 59 RSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNILALRGDPPREQ 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[54][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 125 bits (315), Expect = 1e-27
Identities = 58/111 (52%), Positives = 80/111 (72%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 286
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 287 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNILALRGDPPRTEE 119
[55][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 125 bits (315), Expect = 1e-27
Identities = 60/104 (57%), Positives = 73/104 (70%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M VEK++DAL G N+LALRGDPP QDK+
Sbjct: 78 TCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDKW 121
[56][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 125 bits (315), Expect = 1e-27
Identities = 58/111 (52%), Positives = 80/111 (72%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 286
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTSEKSLDLAA 68
Query: 287 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEE 119
[57][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 125 bits (315), Expect = 1e-27
Identities = 58/111 (52%), Positives = 80/111 (72%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAK 286
A+ P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 9 ASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTSEKSLDLAA 68
Query: 287 KMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
QN +G+ T++HLTCTN E ID AL K+ G++N+LALRGDPP ++
Sbjct: 69 TCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEE 119
[58][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 125 bits (315), Expect = 1e-27
Identities = 59/112 (52%), Positives = 74/112 (66%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A + K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG + +T ++ K
Sbjct: 10 AREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHSKLTCEMVKV 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
Q G+ET MHLTCT+M K+DDAL +G N+LALRGDPP ++K+
Sbjct: 70 AQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREKW 121
[59][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 125 bits (315), Expect = 1e-27
Identities = 56/107 (52%), Positives = 79/107 (73%)
Frame = +2
Query: 119 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 298
P++ SFEFF PKT+ G NLL R++R++A +P F +TWGAGGST++ +LD+A QN
Sbjct: 13 PDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTSEKSLDLAATCQN 72
Query: 299 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+G+ T++HLTCTN E ID AL K+NG++N+LALRGDPP ++
Sbjct: 73 KIGINTVLHLTCTNTDKEIIDSALARAKANGIRNILALRGDPPRTEE 119
[60][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 125 bits (314), Expect = 1e-27
Identities = 58/113 (51%), Positives = 82/113 (72%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A P++ SFEFFPPKT+ G NLL R++RM+A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWI 122
[61][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 125 bits (314), Expect = 1e-27
Identities = 61/117 (52%), Positives = 77/117 (65%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M++ +K+ + A + FSFEFF PKT GV NL ERMDRM P F DITW AGG
Sbjct: 1 MRISQKL-QRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGR 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ ++ D+ Q +G+ET MHLTCTNMPV +IDDAL+ G +N+LALRGDPP
Sbjct: 60 LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPP 116
[62][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 125 bits (314), Expect = 1e-27
Identities = 64/124 (51%), Positives = 82/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 77 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 434 QDKF 445
++ +
Sbjct: 118 KESW 121
[63][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 125 bits (314), Expect = 1e-27
Identities = 61/123 (49%), Positives = 80/123 (65%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M + +K+ +A A K FSFEFFPPKT GV NL +RMDRM P F D+TWGAGG
Sbjct: 1 MHISQKLAQAKAE--GKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGR 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+ +T ++ K Q G+ET MHLTCT+M K+D+AL +G N+LALRGDPP +
Sbjct: 59 HSKLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPPRER 118
Query: 437 DKF 445
+K+
Sbjct: 119 EKW 121
[64][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 125 bits (314), Expect = 1e-27
Identities = 64/124 (51%), Positives = 82/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 77 MKVIEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M V EK+ H A+ P+ SFEFFPPKT GV NL +RMDRM P+F DITWGAGG
Sbjct: 1 MHVKEKLAHSEASGRPS---ISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGG 57
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+D+T ++ Q+ G+ET MHLTCT+MP EK+D AL+ G N+LALRGDPP
Sbjct: 58 RLSDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPRE 117
Query: 434 QDKF 445
++ +
Sbjct: 118 KESW 121
[65][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 125 bits (314), Expect = 1e-27
Identities = 61/101 (60%), Positives = 71/101 (70%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S EFFPPKTE G NLLERM+RM A P F +TWGAGGSTA+ TL++A Q + +
Sbjct: 16 SLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKTLELASLAQKNLNLPI 75
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
MHLTCTNM IDDAL K+ G+ N+LALRGDPP GQD
Sbjct: 76 CMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPPIGQD 116
[66][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 125 bits (314), Expect = 1e-27
Identities = 62/121 (51%), Positives = 80/121 (66%), Gaps = 4/121 (3%)
Frame = +2
Query: 77 MKVIEKIHEA----AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWG 244
MK+ +K+ +A FSFEFF PKT G+ NL +RMDRM +P F DITW
Sbjct: 1 MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN 60
Query: 245 AGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
AGG ++ +T ++ Q+T+G+ET MHLTCTNMPV ID+ALE +G QN+LALRGDP
Sbjct: 61 AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP 120
Query: 425 P 427
P
Sbjct: 121 P 121
[67][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 125 bits (313), Expect = 2e-27
Identities = 61/119 (51%), Positives = 80/119 (67%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ EK+ +A + +SFEFFPP+T G+ NL +R++RM P F DITWGAGG
Sbjct: 1 MKITEKLQKAEKE--GRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGK 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
AD+T + + Q T+G+ET MHL CT MP EK++ AL KS+G QN+LALRGDP G
Sbjct: 59 NADLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAG 117
[68][TOP]
>UniRef100_C9S7I4 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I4_9PEZI
Length = 181
Score = 125 bits (313), Expect = 2e-27
Identities = 58/105 (55%), Positives = 75/105 (71%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q+ G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
T MHLTCT+M +EK++DAL G N+LALRGDPP ++K+V
Sbjct: 78 TCMHLTCTDMGLEKVNDALRKGYKAGCTNILALRGDPPREKEKWV 122
[69][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 125 bits (313), Expect = 2e-27
Identities = 60/114 (52%), Positives = 77/114 (67%)
Frame = +2
Query: 104 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 283
A A + SFEFFPPKT GV NL +RMDRM PSF DITWGAGG A++T ++
Sbjct: 8 ALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAELTCEMV 67
Query: 284 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
Q+ G+ET MHLTCT+MP EK+D+AL++ G N+LALRGDPP ++ +
Sbjct: 68 HVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPPREKESW 121
[70][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 125 bits (313), Expect = 2e-27
Identities = 55/124 (44%), Positives = 87/124 (70%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ +KI AA DP++ ++FEFFPP+T+ G NL+ R+ R+ +P +TWGAGGS
Sbjct: 1 MKLSDKI---AAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGS 57
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D +L++A Q ++T++HLTCTNM +D+ L+ ++ G+QN+LALRGDPP G+
Sbjct: 58 TKDRSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNILALRGDPPRGE 117
Query: 437 DKFV 448
++++
Sbjct: 118 EEWI 121
[71][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 124 bits (312), Expect = 3e-27
Identities = 60/121 (49%), Positives = 84/121 (69%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M V++KI+ D SFEFFPPKT+ G NLL R+ RM+A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMLALNPLFITVTWGAGGS 57
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 437 D 439
+
Sbjct: 118 E 118
[72][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 124 bits (312), Expect = 3e-27
Identities = 61/118 (51%), Positives = 79/118 (66%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGG 253
M+V EK+ + A+ +K FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG 60
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ ++ ++ Q+ +G+ET MHLTCTNMP + IDDAL+ +G QN+LALRGD P
Sbjct: 61 RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAP 118
[73][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 124 bits (311), Expect = 3e-27
Identities = 58/113 (51%), Positives = 81/113 (71%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A P++ SFEFFPPKT+ G NLL R++RM A +P F +TWGAGGST++ +LD+A
Sbjct: 10 ALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTSEKSLDLAAT 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
Q +G+ T++HLTCTN E ID+ALE K G++N+LALRGDPP ++ ++
Sbjct: 70 CQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEYWI 122
[74][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 124 bits (311), Expect = 3e-27
Identities = 58/105 (55%), Positives = 74/105 (70%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKE 119
[75][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 124 bits (311), Expect = 3e-27
Identities = 58/105 (55%), Positives = 74/105 (70%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKE 119
[76][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 124 bits (311), Expect = 3e-27
Identities = 59/114 (51%), Positives = 75/114 (65%)
Frame = +2
Query: 104 AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIA 283
A K FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++
Sbjct: 3 AETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIAELTCEMV 62
Query: 284 KKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
+ Q G+ET MHLTCT+M VEK++DAL G N+LALRGDPP ++K+
Sbjct: 63 TQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEKW 116
[77][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 124 bits (311), Expect = 3e-27
Identities = 58/105 (55%), Positives = 74/105 (70%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
+V SFEFFPPKT GV NL +RMDRM + PSF DITWGAGG +D+T ++ Q+
Sbjct: 15 RVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLSDLTCEMVNVAQSVY 74
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
G+ET MHLTCT+MP+EK++ AL G N+LALRGDPP ++
Sbjct: 75 GLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKE 119
[78][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 123 bits (309), Expect = 6e-27
Identities = 60/123 (48%), Positives = 82/123 (66%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ K+ +A A+D FSFEFF PKT GV NL +RMDRM P F DITW AGG
Sbjct: 1 MKISHKLEKAHAADSTPT-FSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGR 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+++T ++ Q+ +G+ET MHLTCT MP + +++AL++ G QN+LALRGDPP
Sbjct: 60 LSNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVES 119
Query: 437 DKF 445
+K+
Sbjct: 120 EKW 122
[79][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 123 bits (309), Expect = 6e-27
Identities = 59/104 (56%), Positives = 72/104 (69%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKW 121
[80][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 123 bits (309), Expect = 6e-27
Identities = 59/104 (56%), Positives = 72/104 (69%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKT GV NL +RMDRM PSF DITWGAGG A +T ++ Q+ G+E
Sbjct: 18 FSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M EK+D+AL G N+LALRGDPP ++K+
Sbjct: 78 TCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKW 121
[81][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 123 bits (309), Expect = 6e-27
Identities = 60/121 (49%), Positives = 83/121 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M V++KI+ D SFEFFPPKT+ G NLL R+ RM A +P F +TWGAGGS
Sbjct: 1 MSVVQKINSLGPQDR---FISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGS 57
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T++ +LD+A Q +G+ T++HLTCTN + ID+AL+ K NG++N+LALRGDPP +
Sbjct: 58 TSEKSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTE 117
Query: 437 D 439
+
Sbjct: 118 E 118
[82][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 122 bits (306), Expect = 1e-26
Identities = 57/124 (45%), Positives = 85/124 (68%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ +KI E DP+K ++FEFFPP+T+ G NL+ R+ R+ P ITWGAGGS
Sbjct: 1 MKLSQKIAE---HDPSKPFYTFEFFPPRTDQGTENLIARISRLSTLDPLAISITWGAGGS 57
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T + +LD+A Q+ ++T++HLTCTNM IDD L+ +K G++ +LALRGDPP G+
Sbjct: 58 TKERSLDLASITQSQHRLDTILHLTCTNMEQGLIDDVLKDVKDRGIETILALRGDPPRGE 117
Query: 437 DKFV 448
++++
Sbjct: 118 EEWI 121
[83][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 121 bits (303), Expect = 3e-26
Identities = 62/125 (49%), Positives = 81/125 (64%), Gaps = 2/125 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 254 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 431 GQDKF 445
+ +
Sbjct: 120 DAENW 124
[84][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 121 bits (303), Expect = 3e-26
Identities = 62/125 (49%), Positives = 81/125 (64%), Gaps = 2/125 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 254 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 431 GQDKF 445
+ +
Sbjct: 120 DAENW 124
[85][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 121 bits (303), Expect = 3e-26
Identities = 62/125 (49%), Positives = 81/125 (64%), Gaps = 2/125 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ EK+ + + K +SFE+F PKT GV NL +RMDRM S P F DITW AGG
Sbjct: 1 MKITEKLEQHRQTS-GKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGG 59
Query: 254 ST-ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
+ ++ D+ Q+ +G+ET MHLTCTNMP+ IDDALE +G QN+LALRGDPP
Sbjct: 60 GRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPR 119
Query: 431 GQDKF 445
+ +
Sbjct: 120 DAENW 124
[86][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 120 bits (302), Expect = 4e-26
Identities = 56/104 (53%), Positives = 72/104 (69%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
MHLTCT+M EK++DAL G N+LALRGDPP Q+K+
Sbjct: 78 ACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREQEKW 121
[87][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 120 bits (301), Expect = 5e-26
Identities = 56/104 (53%), Positives = 73/104 (70%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RM+RM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIAELTCEMVVQAQTYLGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M EK++DAL G N+LALRGDPP ++K+
Sbjct: 78 TCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEKW 121
[88][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 120 bits (301), Expect = 5e-26
Identities = 58/101 (57%), Positives = 73/101 (72%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S EFFPPKTE G NLLERM RM A P F +TWGAGG+TA+ TL++A +N++ +
Sbjct: 17 SLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEKTLELATLAENSLNLNV 76
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+HLTCTNM ID+ALE K G++N+LALRGDPP G+D
Sbjct: 77 CIHLTCTNMSRGIIDEALEACKKIGIRNILALRGDPPIGED 117
[89][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 120 bits (300), Expect = 6e-26
Identities = 55/104 (52%), Positives = 74/104 (71%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFE+FPPKT GV NL +RMDRM P F DITWGAGG A++T ++ + Q +G+E
Sbjct: 18 FSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLE 77
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T MHLTCT+M EK+++AL+ G N+LALRGDPP ++++
Sbjct: 78 TCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKERW 121
[90][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 119 bits (297), Expect = 1e-25
Identities = 59/121 (48%), Positives = 82/121 (67%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M V+E+I A P++ SFEFFPPKT+ G NLL R+ RM +P F +TWGAGGS
Sbjct: 1 MSVVERIQ---ALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGS 57
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T++ +L++A Q +G+ T++HLTCTN IDDAL K+ G++N+LALRGDPP +
Sbjct: 58 TSEKSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPPRTR 117
Query: 437 D 439
+
Sbjct: 118 E 118
[91][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 119 bits (297), Expect = 1e-25
Identities = 61/118 (51%), Positives = 76/118 (64%)
Frame = +2
Query: 86 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 265
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 266 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGED 116
[92][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 118 bits (296), Expect = 2e-25
Identities = 61/121 (50%), Positives = 79/121 (65%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
M I K+ A P++ FS EFFPPKT++G+ N R+ RM A P F ITWGAGGS
Sbjct: 1 MSTITKL--IAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGS 58
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +LDIA + Q ++G++ +HLTCTNM ID ALE G+ N+LALRGDPP G+
Sbjct: 59 TAKKSLDIASECQ-SMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGE 117
Query: 437 D 439
+
Sbjct: 118 E 118
[93][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 118 bits (296), Expect = 2e-25
Identities = 61/118 (51%), Positives = 76/118 (64%)
Frame = +2
Query: 86 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 265
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 266 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGED 116
[94][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 118 bits (296), Expect = 2e-25
Identities = 61/118 (51%), Positives = 76/118 (64%)
Frame = +2
Query: 86 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 265
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 266 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGED 116
[95][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 118 bits (296), Expect = 2e-25
Identities = 61/118 (51%), Positives = 76/118 (64%)
Frame = +2
Query: 86 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 265
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 266 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGED 116
[96][TOP]
>UniRef100_A6ZWM3 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae YJM789 RepID=A6ZWM3_YEAS7
Length = 441
Score = 118 bits (296), Expect = 2e-25
Identities = 61/118 (51%), Positives = 76/118 (64%)
Frame = +2
Query: 86 IEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD 265
I ++ A AS S EFFPPKTE G NL+ERM RM A P F +TWGAGG+TA+
Sbjct: 3 IRDLYHARASP----FISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAE 58
Query: 266 VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
TL +A Q T+ + MHLTCTN IDDAL+ + G++N+LALRGDPP G+D
Sbjct: 59 KTLALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGED 116
[97][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 117 bits (294), Expect = 3e-25
Identities = 59/120 (49%), Positives = 75/120 (62%), Gaps = 3/120 (2%)
Frame = +2
Query: 77 MKVIEKIHE---AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGA 247
M++ +K+ + AA + K FSFEFF PKT GV NL +RMDRM P F DITW A
Sbjct: 1 MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA 60
Query: 248 GGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
GG + T ++ Q +G+ET MHLTCTNM +D+ALE G +N+LALRGDPP
Sbjct: 61 GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENILALRGDPP 120
[98][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 117 bits (292), Expect = 5e-25
Identities = 65/134 (48%), Positives = 85/134 (63%), Gaps = 1/134 (0%)
Frame = +2
Query: 29 IPSLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV 208
+PSL L + K K+ +KI AA + FS EFFPPKT G NL R+DRM
Sbjct: 5 VPSLELPPEAAKSHAMDKITDKI---AALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRMA 61
Query: 209 -AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKS 385
A P F ++TWGAGGSTA +L++A+ Q +G+ T +HLTCTNM ID AL+ K+
Sbjct: 62 RALRPLFVNVTWGAGGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAKA 121
Query: 386 NGLQNVLALRGDPP 427
G++N+LALRGDPP
Sbjct: 122 LGIRNILALRGDPP 135
[99][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 117 bits (292), Expect = 5e-25
Identities = 62/121 (51%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP +
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[100][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 116 bits (291), Expect = 7e-25
Identities = 57/105 (54%), Positives = 73/105 (69%)
Frame = +2
Query: 113 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 292
SD + + S EFFPPKTE G NLLERM+RM A P F +TWGAGGST++ TL++A+
Sbjct: 8 SDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKTLELAQIA 67
Query: 293 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
Q + V MHLTCTNM I +AL+ +S G++N+LALRGD P
Sbjct: 68 QRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAP 112
[101][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 116 bits (291), Expect = 7e-25
Identities = 59/117 (50%), Positives = 81/117 (69%), Gaps = 1/117 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ +K+ D +V +S+E+FPPKT GVVNL R++RM P+F D+TWGAGG
Sbjct: 1 MKITDKLQLPEYRD--RVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGG 58
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
S++D+T I K Q+ G++T MHLTCTNM ++ID+ALE G +N+LALRGDP
Sbjct: 59 SSSDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNILALRGDP 115
[102][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 116 bits (290), Expect = 9e-25
Identities = 61/121 (50%), Positives = 82/121 (67%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ EKI AA P+ FS EFFPPKT+ G VNL R++RM A P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGT 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[103][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 116 bits (290), Expect = 9e-25
Identities = 62/121 (51%), Positives = 79/121 (65%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ EKI AA P+ FS EFFPPKT G NL R+DRM A P F +TWGAGGS
Sbjct: 3 KITEKI---AALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q +G+ T +HLTCTNM +D ALE K+ G++N+LALRGDPP
Sbjct: 60 TATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSD 119
Query: 437 D 439
+
Sbjct: 120 E 120
[104][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 115 bits (289), Expect = 1e-24
Identities = 57/116 (49%), Positives = 78/116 (67%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGST 259
K+I+KI E +SFEFFPPKT++G+ NLL R+ RM +P F +TWGAGG+T
Sbjct: 3 KIIDKIKELKGEP----FYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTT 58
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ TLD+A Q + + T +HLTCTN + ID+AL+ NG++N+LALRGDPP
Sbjct: 59 SSKTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPP 114
[105][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 114 bits (285), Expect = 3e-24
Identities = 60/121 (49%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ EKI AA P FS EFFPPKT+ G VNL R++RM P F +TWGAGG+
Sbjct: 3 KITEKI---AALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGT 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[106][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 114 bits (284), Expect = 4e-24
Identities = 61/121 (50%), Positives = 81/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[107][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 114 bits (284), Expect = 4e-24
Identities = 60/120 (50%), Positives = 79/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKI-HEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI H+ AA P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP ++
Sbjct: 61 AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE 120
[108][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 114 bits (284), Expect = 4e-24
Identities = 60/120 (50%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM IDDAL+ K+ G++N+LALRGDPP +
Sbjct: 61 ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNILALRGDPPRSDE 120
[109][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 114 bits (284), Expect = 4e-24
Identities = 61/121 (50%), Positives = 81/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[110][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 114 bits (284), Expect = 4e-24
Identities = 61/121 (50%), Positives = 81/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA PN+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 30 KITDKI---AALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGS 86
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP +
Sbjct: 87 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 146
Query: 437 D 439
+
Sbjct: 147 E 147
[111][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 113 bits (282), Expect = 8e-24
Identities = 59/121 (48%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP +
Sbjct: 60 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[112][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 113 bits (282), Expect = 8e-24
Identities = 59/121 (48%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 51 KITDKI---AALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 107
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP +
Sbjct: 108 TAQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 167
Query: 437 D 439
+
Sbjct: 168 E 168
[113][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 112 bits (279), Expect = 2e-23
Identities = 58/120 (48%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
++KI + A+ P + FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST
Sbjct: 1 MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+ +L++A+ Q VG+ T +HLTCTNM + ID+AL K+ G++N+LALRGDPP ++
Sbjct: 61 SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE 120
[114][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 112 bits (279), Expect = 2e-23
Identities = 58/120 (48%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHE-AAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGST 259
+EKI + AA P+ FS EFFPPKT G NL +R++RM P F ++TWGAGGST
Sbjct: 1 MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM +D LE K G++N+LALRGDPP +
Sbjct: 61 AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE 120
[115][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 112 bits (279), Expect = 2e-23
Identities = 63/134 (47%), Positives = 85/134 (63%), Gaps = 1/134 (0%)
Frame = +2
Query: 29 IPSLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV 208
+PSL L + + K+ K+ +KI AA S EFFPPKT G NL +R+DRM
Sbjct: 5 LPSLELPVEAGKNHAMDKITDKI---AALPAETNYCSLEFFPPKTAMGFSNLRDRLDRMA 61
Query: 209 -AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKS 385
A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM + ID LE K+
Sbjct: 62 RALRPLFVNVTWGAGGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAKA 121
Query: 386 NGLQNVLALRGDPP 427
G++N+LALRGDPP
Sbjct: 122 LGIRNILALRGDPP 135
[116][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 112 bits (279), Expect = 2e-23
Identities = 59/121 (48%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM +D+ALE K G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[117][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 111 bits (278), Expect = 2e-23
Identities = 60/117 (51%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA N FS EFFPPKT G NL +R+DRM A P F ++TWGAGGS
Sbjct: 3 KITDKI---AALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
TA +L++A+ Q +G+ T +HLTCTNM +D AL+ K G++N+LALRGDPP
Sbjct: 60 TAFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPP 116
[118][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 111 bits (278), Expect = 2e-23
Identities = 59/120 (49%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDP-NKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + A+ P N FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE 120
[119][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 111 bits (278), Expect = 2e-23
Identities = 61/121 (50%), Positives = 82/121 (67%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI EA D + FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KISDKI-EALPKDAH--YFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q +G+ T +HLTCTNM ID+ALE K+ G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[120][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 111 bits (278), Expect = 2e-23
Identities = 59/121 (48%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ EKI AA P+ FS EFFPPKT G NL R++RM A P F +TWGAGGS
Sbjct: 4 KITEKI---AALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS 60
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T++HLTCTNM + +D AL+ K G++N+LALRGDPP +
Sbjct: 61 TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE 120
Query: 437 D 439
+
Sbjct: 121 E 121
[121][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 111 bits (278), Expect = 2e-23
Identities = 60/121 (49%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM ID+ALE K G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[122][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 111 bits (277), Expect = 3e-23
Identities = 55/110 (50%), Positives = 71/110 (64%)
Frame = +2
Query: 113 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 292
S+ N+ S EFFPPKT+ G NLL R++RM A P F +TWGAGGSTA+ TL++A
Sbjct: 9 SELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEKTLELAALA 68
Query: 293 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK 442
Q + + MHLTCTNM +D AL K G++N+LALRGD P D+
Sbjct: 69 QRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNILALRGDMPLAADE 118
[123][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 111 bits (277), Expect = 3e-23
Identities = 59/121 (48%), Positives = 79/121 (65%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
K+ +KI AA P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGS
Sbjct: 3 KITDKI---AALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGS 59
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
TA +L++A+ Q + + T +HLTCTNM +D ALE K G++N+LALRGDPP +
Sbjct: 60 TAARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPPRSE 119
Query: 437 D 439
+
Sbjct: 120 E 120
[124][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 111 bits (277), Expect = 3e-23
Identities = 55/106 (51%), Positives = 69/106 (65%), Gaps = 1/106 (0%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGGSTADVTLDIAKKMQNT 301
KV +S+EFFPPKT GV NL R+DRM P F D+TWGAGG+++++T I +Q
Sbjct: 15 KVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTD 74
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
V+T MHLTCTNM E ID AL+ G +N+LALRGDP D
Sbjct: 75 FEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTD 120
[125][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 110 bits (276), Expect = 4e-23
Identities = 60/120 (50%), Positives = 79/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + S P+ FS EFFPPKT G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM + IDDALE K G++N+LALRGD P ++
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE 120
[126][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 110 bits (275), Expect = 5e-23
Identities = 57/124 (45%), Positives = 82/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 253
M+ I I+ AA +D ++ V SFEFFPPKT++G LLE+ + ++ P FC +T+GAGG
Sbjct: 7 MQFIRDIY-AAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVTYGAGG 65
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T D TL I ++Q + TM+HLTC N E++ D +E +S G++N+LALRGDPP G
Sbjct: 66 GTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNILALRGDPPGG 125
Query: 434 QDKF 445
+F
Sbjct: 126 NGEF 129
[127][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 110 bits (275), Expect = 5e-23
Identities = 58/120 (48%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
[128][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 110 bits (275), Expect = 5e-23
Identities = 56/120 (46%), Positives = 79/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F ++TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
[129][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 110 bits (275), Expect = 5e-23
Identities = 58/120 (48%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
[130][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 110 bits (275), Expect = 5e-23
Identities = 58/120 (48%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAAS-DPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI + A+ P+ FS EFFPPKT+ G NL R++RM A P F +TWGAGGST
Sbjct: 1 MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM +D AL K+ G++N+LALRGDPP ++
Sbjct: 61 AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE 120
[131][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 110 bits (274), Expect = 6e-23
Identities = 58/120 (48%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
[132][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 110 bits (274), Expect = 6e-23
Identities = 58/120 (48%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+EKI A+ P FS EFFPPKT+ G NL R++RM A P F +TWGAGG+T
Sbjct: 1 MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
A +L++A+ Q +G+ T +HLTCTNM ID AL+ K+ G++N+LALRGDPP +
Sbjct: 61 ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE 120
[133][TOP]
>UniRef100_Q08QG9 Methylenetetrahydrofolate reductase n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08QG9_STIAU
Length = 327
Score = 109 bits (273), Expect = 8e-23
Identities = 48/110 (43%), Positives = 73/110 (66%)
Frame = +2
Query: 116 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 295
+P+ FSFEFFPPKT++G NLL+ ++ + P F +T+GAGGST + TL + +++
Sbjct: 45 NPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIK 104
Query: 296 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
T G+E+M HLTC +++ + L+ +++ L NVL LRGDPP GQ F
Sbjct: 105 QTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNVLVLRGDPPRGQTTF 154
[134][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 109 bits (273), Expect = 8e-23
Identities = 54/103 (52%), Positives = 73/103 (70%), Gaps = 1/103 (0%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
FS EFFPPKT G NL +R+ RM A P F ++TWGAGGST+ +L++A+ Q +G+
Sbjct: 18 FSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGSTSQKSLELAELCQRELGL 77
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
T +HLTCTNM + ID ALE K+ G++N+LALRGDPP ++
Sbjct: 78 TTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE 120
[135][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 109 bits (273), Expect = 8e-23
Identities = 56/120 (46%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
[136][TOP]
>UniRef100_A7HDS2 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp.
Fw109-5 RepID=A7HDS2_ANADF
Length = 300
Score = 109 bits (272), Expect = 1e-22
Identities = 51/112 (45%), Positives = 73/112 (65%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A + + VFSFEFFPPKT+DGV L E ++ + +P++ +T+GAGGST TL++ K+
Sbjct: 10 ARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTRQRTLELVKR 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
++ VE M HLTC E++ L+ + G+QNVLALRGDPP G+ F
Sbjct: 70 LKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPPRGETSF 121
[137][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 108 bits (271), Expect = 1e-22
Identities = 53/101 (52%), Positives = 69/101 (68%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S EFFPPKTE G NLL RM+RM A +P F +TW AGG+TA TL++A Q + V
Sbjct: 27 SLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGKTLELATIAQRELNVPV 86
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
MHLTCTNM + ID+AL+ + ++N+LALRGDP G++
Sbjct: 87 CMHLTCTNMNKDIIDEALKAARDADIRNILALRGDPAIGEE 127
[138][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 108 bits (271), Expect = 1e-22
Identities = 51/104 (49%), Positives = 77/104 (74%), Gaps = 3/104 (2%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVA---HSPSFCDITWGAGGSTADVTLDIAKKMQNTVG 307
++EFFPP T+ G VNLL+R+ R+ + +P +TWGAGGSTA+ +L++A+++ + +G
Sbjct: 17 NYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGSTAEKSLELAQQVVD-MG 75
Query: 308 VETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
VE ++HLTCTNMP +K+D AL K G+ N+LALRGDPP ++
Sbjct: 76 VEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEE 119
[139][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 108 bits (271), Expect = 1e-22
Identities = 56/120 (46%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +2
Query: 86 IEKIHEAAASDPNKV-VFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGST 259
+E+I + A+ P FS EFFPPKT G +NL R++RM A P F +TWGAGGST
Sbjct: 1 MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST 60
Query: 260 ADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+L++A+ Q +G+ T +HLTCTNM +DDAL + G++N+LALRGDPP ++
Sbjct: 61 VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE 120
[140][TOP]
>UniRef100_Q2ILB5 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-C RepID=Q2ILB5_ANADE
Length = 300
Score = 108 bits (270), Expect = 2e-22
Identities = 51/113 (45%), Positives = 72/113 (63%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+D+ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIDLVKR 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
++ VE M H+TC E+I L+ + G+QNVLALRGD P GQ FV
Sbjct: 70 LKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAPRGQSAFV 122
[141][TOP]
>UniRef100_B4UHX4 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter sp. K
RepID=B4UHX4_ANASK
Length = 300
Score = 108 bits (270), Expect = 2e-22
Identities = 50/113 (44%), Positives = 73/113 (64%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGAFV 122
[142][TOP]
>UniRef100_B8JEQ3 Methylenetetrahydrofolate reductase n=1 Tax=Anaeromyxobacter
dehalogenans 2CP-1 RepID=B8JEQ3_ANAD2
Length = 300
Score = 108 bits (269), Expect = 2e-22
Identities = 50/113 (44%), Positives = 73/113 (64%)
Frame = +2
Query: 110 ASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKK 289
A + + +FSFEFFPPKT+DGV L E ++ + P++ +T+GAGGST T+++ K+
Sbjct: 10 ARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTRAKTIELVKR 69
Query: 290 MQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
++ VE M H+TC ++I L+ + G+QNVLALRGDPP GQ FV
Sbjct: 70 LKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGGFV 122
[143][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 107 bits (267), Expect = 4e-22
Identities = 54/101 (53%), Positives = 67/101 (66%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S EFFPPKT+ G NL RM RM A +P F ITWGAGG+TA TL++A Q + V
Sbjct: 36 SLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTAKKTLELATVAQRELNVPV 95
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
MHLTCTN E ID+AL+ ++N+LALRGDPP G++
Sbjct: 96 CMHLTCTNTNKEIIDEALKLAHEADIRNILALRGDPPVGEE 136
[144][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 106 bits (265), Expect = 7e-22
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 6/124 (4%)
Frame = +2
Query: 92 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPS-FCDITWGAGGSTADV 268
KI + D S E+FPP+T+ GV NL RMDRM+ ++ + + D+TWGAGGSTAD+
Sbjct: 12 KIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTADL 71
Query: 269 TLDIAKKMQNTVGVETMMHLTCTNM-----PVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+L++A T G + MHLTCTNM PV+ + DAL+ G++N++ALRGDPP G
Sbjct: 72 SLELALHAHKT-GHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPPEG 130
Query: 434 QDKF 445
+ ++
Sbjct: 131 EKEW 134
[145][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 106 bits (264), Expect = 9e-22
Identities = 56/122 (45%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLER-MDRMVAHSPSFCDITWGAGG 253
M+ I I+ A A + V S EFFP KTE+G NLLE+ + +++ P+FC +T+GAGG
Sbjct: 1 MQFIRDIY-AEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGG 59
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T D TL I ++Q + MMHLTC N E++ L+ K G+QN+LALRGDPP G
Sbjct: 60 GTRDKTLGIVDRIQRHHNLPAMMHLTCVNSTREELGHVLDEAKGRGIQNILALRGDPPSG 119
Query: 434 QD 439
D
Sbjct: 120 GD 121
[146][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 105 bits (263), Expect = 1e-21
Identities = 52/102 (50%), Positives = 67/102 (65%), Gaps = 1/102 (0%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
+SFEFFPPKTE G+ NLL R+DRM P F ITWG+ GST TL +A Q V
Sbjct: 1 YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV 60
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
+ ++HL+CT + E+I L KS+G+ N+LALRGDPP G+
Sbjct: 61 DVLLHLSCTGLTREQIGHVLAMAKSSGVHNILALRGDPPQGK 102
[147][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 105 bits (262), Expect = 2e-21
Identities = 54/122 (44%), Positives = 73/122 (59%), Gaps = 4/122 (3%)
Frame = +2
Query: 83 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 262
+IEKIH+ K FS EFFPP+T +G VNL+ R DRM P FCDITW G +
Sbjct: 21 LIEKIHKHIGK--KKKFFSLEFFPPRTPNGAVNLVARFDRMSQGGPLFCDITWHPAGDPS 78
Query: 263 ----DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
+ IA N G+ETM+H+TC N+ + + L+ K+ G++N+LALRGDPP
Sbjct: 79 GDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKKAKNLGIRNILALRGDPPK 138
Query: 431 GQ 436
G+
Sbjct: 139 GE 140
[148][TOP]
>UniRef100_C1XWC8 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus silvanus
DSM 9946 RepID=C1XWC8_9DEIN
Length = 294
Score = 105 bits (262), Expect = 2e-21
Identities = 51/118 (43%), Positives = 74/118 (62%)
Frame = +2
Query: 92 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVT 271
KIH A P K +FSFEFFPPKTE+G L + + P+F +T+GAGGS T
Sbjct: 2 KIHTQFA--PGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKT 59
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
++ ++++ VG+E M HLTC E+I + LE ++ G +N++A+RGDPP GQ +F
Sbjct: 60 VEWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAVRGDPPKGQREF 117
[149][TOP]
>UniRef100_A5KL25 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus torques
ATCC 27756 RepID=A5KL25_9FIRM
Length = 289
Score = 104 bits (259), Expect = 4e-21
Identities = 48/119 (40%), Positives = 77/119 (64%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+++ E +K+ SFE FPPKT+ G ++ D M +P+F +T+GAGG
Sbjct: 1 MKIIDRLKE------DKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T+ T IA +++ +GV ++ HLTC + +E++ D +E +K NG++N+LALRGD P G
Sbjct: 55 TSKNTAKIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEG 113
[150][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 103 bits (258), Expect = 5e-21
Identities = 55/123 (44%), Positives = 77/123 (62%), Gaps = 2/123 (1%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPN-KVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAG 250
MK+++ I + PN +SFE+FPPKT G+ NL R+ RM + P F +TWG
Sbjct: 1 MKIVDLIDKI----PNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTA 56
Query: 251 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
GSTA+V++ +AK ++ + +HLTCTN+ ID ALET K G++N+LALRGDPP
Sbjct: 57 GSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPPL 116
Query: 431 GQD 439
D
Sbjct: 117 NSD 119
[151][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 103 bits (256), Expect = 8e-21
Identities = 46/81 (56%), Positives = 60/81 (74%)
Frame = +2
Query: 203 MVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIK 382
M A P F DITW AGG T+D+T ++ K Q +G+ET MHLTCTNMP EK+D AL+ K
Sbjct: 1 MRALGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAK 60
Query: 383 SNGLQNVLALRGDPPHGQDKF 445
+G +N+LALRGDPP G+D++
Sbjct: 61 EHGCRNILALRGDPPMGKDEW 81
[152][TOP]
>UniRef100_B6FS52 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium nexile DSM
1787 RepID=B6FS52_9CLOT
Length = 288
Score = 102 bits (253), Expect = 2e-20
Identities = 50/117 (42%), Positives = 74/117 (63%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ +++ E N+V SFE FPPKT+ G +LE + + A PSF +T+GAGG
Sbjct: 1 MKIKDRLSE------NRVNISFEVFPPKTDAGYGKVLEATEEIAALKPSFISVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
T+ T+ IA +QN +GV ++ HLTC + E++ +E +K G+QN+LALRGD P
Sbjct: 55 TSKNTVKIASHIQNDLGVASLAHLTCASSTKEEVRQVIEQLKEQGIQNILALRGDIP 111
[153][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 101 bits (251), Expect = 3e-20
Identities = 48/113 (42%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLE-RMDRMVAHSPSFCDITWGAGGSTADVTLDIA 283
AA D NK S+EF+PP++E N ++ ++ + SP F D+TWGAGG T++ T+ +
Sbjct: 10 AAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGRTSETTMRLC 69
Query: 284 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
K +QN MH+TCTNM + I + L+ K +G++N+LALRGDPP G +
Sbjct: 70 KDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRGDE 122
[154][TOP]
>UniRef100_A3DBL1 Methylenetetrahydrofolate reductase n=3 Tax=Clostridium
thermocellum RepID=A3DBL1_CLOTH
Length = 291
Score = 100 bits (249), Expect = 5e-20
Identities = 46/107 (42%), Positives = 68/107 (63%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
K V SFE FPPK + + ++ +++ P F +T+GAGGS D T++IA K++N
Sbjct: 11 KPVISFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTIEIASKIKNEY 70
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
G+E+M HLTC E+ID L +++ + L+N+LALRGDPP Q F
Sbjct: 71 GIESMAHLTCVGHSKEEIDALLTSMREHNLENILALRGDPPANQPDF 117
[155][TOP]
>UniRef100_Q04NW1 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira
borgpetersenii serovar Hardjo-bovis RepID=Q04NW1_LEPBJ
Length = 290
Score = 99.8 bits (247), Expect = 9e-20
Identities = 49/123 (39%), Positives = 73/123 (59%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK + +I+ +A V+SFEFFPPKT+DG + L+ + + P F +T+GAGGS
Sbjct: 1 MKKVSEIYGSAKGP----VYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGS 56
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D T I ++ T+ H TC ++I L+ I+S+G+ N++ALRGDPP G+
Sbjct: 57 TRDKTAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGE 116
Query: 437 DKF 445
KF
Sbjct: 117 GKF 119
[156][TOP]
>UniRef100_B0SH77 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira biflexa
serovar Patoc RepID=B0SH77_LEPBA
Length = 295
Score = 99.8 bits (247), Expect = 9e-20
Identities = 45/117 (38%), Positives = 68/117 (58%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTL 274
+H + + SFEFFPPK E+ +L + + +P++ +T+GAGGST +T
Sbjct: 1 MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH 60
Query: 275 DIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
D+ K+QN G+ + HLTC E+I D L+ +G+ N++ALRGDPP GQ F
Sbjct: 61 DLVVKLQNETGLTIVSHLTCVGSTKEEIGDILKRYDKSGIHNIMALRGDPPKGQQDF 117
[157][TOP]
>UniRef100_UPI000196BD8E hypothetical protein CATMIT_02257 n=1 Tax=Catenibacterium mitsuokai
DSM 15897 RepID=UPI000196BD8E
Length = 287
Score = 99.0 bits (245), Expect = 1e-19
Identities = 47/117 (40%), Positives = 74/117 (63%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+ ++E +KV SFE FPPKT N+L+ +++ + +P+F +T+GAGG
Sbjct: 1 MKIIDLLNE------DKVTLSFEVFPPKTSGRYENVLKAAEKIASLNPNFMSVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
T+ T+ +AK + GVE M HLTC + E ++ +E K NG++N++ALRGD P
Sbjct: 55 TSAHTVALAKDIHEKYGVEVMAHLTCVSSTKEHVESMVEQFKENGIENIMALRGDIP 111
[158][TOP]
>UniRef100_B0N2P6 Methylenetetrahydrofolate reductase n=2 Tax=Bacteria
RepID=B0N2P6_9FIRM
Length = 296
Score = 99.0 bits (245), Expect = 1e-19
Identities = 47/122 (38%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 253
MK+I+ +H + SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHR-------RPTLSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGG 53
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
ST + T++IA K++N +E + HL+C + E++ L+++K+N ++NVLALRGD P G
Sbjct: 54 STTENTVEIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENVLALRGDYPRG 113
Query: 434 QD 439
D
Sbjct: 114 YD 115
[159][TOP]
>UniRef100_B8DJ94 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio vulgaris
str. 'Miyazaki F' RepID=B8DJ94_DESVM
Length = 291
Score = 98.6 bits (244), Expect = 2e-19
Identities = 52/121 (42%), Positives = 73/121 (60%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ ++I AA++ P +S EFFPPK + ++R+ A P F +T+GAGGS
Sbjct: 1 MKIRDRI--AASTRP---FYSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGS 55
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D TL+I ++N +G+E M HLTC E+I D L ++ + NVLALRGD P GQ
Sbjct: 56 TQDNTLEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQ 115
Query: 437 D 439
D
Sbjct: 116 D 116
[160][TOP]
>UniRef100_A1VEZ2 Methylenetetrahydrofolate reductase n=3 Tax=Desulfovibrio vulgaris
RepID=A1VEZ2_DESVV
Length = 291
Score = 98.6 bits (244), Expect = 2e-19
Identities = 50/120 (41%), Positives = 69/120 (57%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+ E I + + +S EFFPPK + ++R+ A P F +T+GAGG
Sbjct: 1 MKIAEAIERQS-----RPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGG 55
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D TLDI ++N +G+E M HLTC E+I L ++ G++NVLALRGDPP GQ
Sbjct: 56 TQDNTLDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQ 115
[161][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 97.8 bits (242), Expect = 3e-19
Identities = 45/110 (40%), Positives = 67/110 (60%)
Frame = +2
Query: 116 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 295
+P+ FSFEFFPP+T++G NLL+ ++ + P F +T GAGGST T+++ +++
Sbjct: 8 NPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRIK 67
Query: 296 NTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
G+E M HLTC ++ LE + + + NVL LRGDPP GQ F
Sbjct: 68 QEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTVF 117
[162][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 97.8 bits (242), Expect = 3e-19
Identities = 46/106 (43%), Positives = 64/106 (60%), Gaps = 4/106 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD----VTLDIAKKMQNT 301
FS EFFPP+T +G VNLL DR+ + P FCD+TW G + ++ IA N
Sbjct: 12 FSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTSSMTIASTALNY 71
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
G+ETM+H+TC N + L K+ G++N+LALRGDPP G++
Sbjct: 72 CGLETMLHMTCANQTKASVTKNLHKAKTLGIRNILALRGDPPDGEE 117
[163][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 97.4 bits (241), Expect = 4e-19
Identities = 44/100 (44%), Positives = 64/100 (64%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKTE+ NL + ++ P FC +T+GAGGST + T + A ++Q T G+E
Sbjct: 15 FSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETALEIQQTTGIE 74
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
HL+C I + LE +S+G+++++ALRGD P G
Sbjct: 75 CAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSG 114
[164][TOP]
>UniRef100_C8X270 5,10-methylenetetrahydrofolate reductase n=1 Tax=Desulfohalobium
retbaense DSM 5692 RepID=C8X270_9DELT
Length = 293
Score = 97.1 bits (240), Expect = 6e-19
Identities = 46/110 (41%), Positives = 66/110 (60%)
Frame = +2
Query: 119 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 298
P K S EFFPPK E E + ++ + P F +T+GAGGST D TL + +++
Sbjct: 9 PGKKFISLEFFPPKDEGNWPGFFEEVHQLASMDPLFVSVTYGAGGSTQDNTLRLVSRLKQ 68
Query: 299 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
+G+E M HLTC + D + +++++ + NVLALRGDPP GQD FV
Sbjct: 69 -MGLEPMAHLTCVGASAATLHDFMRSLQASDIDNVLALRGDPPQGQDTFV 117
[165][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 97.1 bits (240), Expect = 6e-19
Identities = 46/113 (40%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERM-DRMVAHSPSFCDITWGAGGSTADVTLDIA 283
AA D +K S+E +PP++E ++++ + + SP F D+TWGAGG T+D T+ +
Sbjct: 10 AAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGRTSDTTMRLC 69
Query: 284 KKMQNTV-GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
K +Q+ MH+TCTN P I++AL+ K++G++N+LALRGDPP G++
Sbjct: 70 KDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRGEE 122
[166][TOP]
>UniRef100_Q8EY55 Methylenetetrahydrofolate reductase n=1 Tax=Leptospira interrogans
RepID=Q8EY55_LEPIN
Length = 310
Score = 96.7 bits (239), Expect = 7e-19
Identities = 48/123 (39%), Positives = 74/123 (60%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 437 DKF 445
+F
Sbjct: 134 GEF 136
[167][TOP]
>UniRef100_Q75G11 Methylenetetrahydrofolate reductase n=2 Tax=Leptospira interrogans
RepID=Q75G11_LEPIC
Length = 310
Score = 96.7 bits (239), Expect = 7e-19
Identities = 48/123 (39%), Positives = 74/123 (60%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK + +I+ +A V+SFEFFPPKT +G L+E + + +P F +T+GAGGS
Sbjct: 18 MKKVSEIYGSAKGP----VYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGS 73
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D T+ I ++ T+ H TC +I + L+ I+S+G+ N++ALRGDPP G+
Sbjct: 74 TRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGE 133
Query: 437 DKF 445
+F
Sbjct: 134 GEF 136
[168][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 96.7 bits (239), Expect = 7e-19
Identities = 51/126 (40%), Positives = 71/126 (56%), Gaps = 4/126 (3%)
Frame = +2
Query: 83 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW----GAG 250
+I+KI + S +S EFFPP+T+ G VNL+ R DR+ +P F D+TW +G
Sbjct: 26 IIQKIRKRINSGDK--FYSLEFFPPRTDSGGVNLIARFDRLAIGNPLFIDVTWHPKGNSG 83
Query: 251 GSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPH 430
G +L IA N G+++M+H+TC N E ID L K GL+N+LALRGD
Sbjct: 84 GDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGLRNILALRGDVSD 143
Query: 431 GQDKFV 448
D+ V
Sbjct: 144 SIDESV 149
[169][TOP]
>UniRef100_C1DUH1 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
azorense Az-Fu1 RepID=C1DUH1_SULAA
Length = 291
Score = 96.3 bits (238), Expect = 1e-18
Identities = 49/122 (40%), Positives = 74/122 (60%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+++K+ + KV SFEFFPPKT++ +L + ++ + +P+F +T+GAGGS
Sbjct: 1 MKIVDKLKK------EKVSISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGS 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T + T DI KK+ + M HLTC ++I LE K+ G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENILALRGDIPLSF 114
Query: 437 DK 442
DK
Sbjct: 115 DK 116
[170][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 95.9 bits (237), Expect = 1e-18
Identities = 49/118 (41%), Positives = 73/118 (61%), Gaps = 1/118 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHS-PSFCDITWGAGG 253
MK+ E++ + D + +SFEFFPPKT G+ NL RM RM P F +TW + G
Sbjct: 1 MKISEQLEQLPKDD---IHYSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAG 57
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
S+A +L + +Q+ GV + +H+TC+N+ E I L+ K+ G++N+LALRGDPP
Sbjct: 58 SSAAESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNILALRGDPP 115
[171][TOP]
>UniRef100_C4FKN7 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
yellowstonense SS-5 RepID=C4FKN7_9AQUI
Length = 292
Score = 95.5 bits (236), Expect = 2e-18
Identities = 49/122 (40%), Positives = 70/122 (57%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+K+ K+ SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KISISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T + T DI KK+ + M HLTC ++I L+ K G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENILALRGDMPLNF 114
Query: 437 DK 442
+K
Sbjct: 115 EK 116
[172][TOP]
>UniRef100_C0C3T3 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium hylemonae
DSM 15053 RepID=C0C3T3_9CLOT
Length = 289
Score = 95.5 bits (236), Expect = 2e-18
Identities = 43/97 (44%), Positives = 65/97 (67%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFE FPPKT+ G ++L +++ A PSF +T+GAGG T+ T++IA +QN +GV +
Sbjct: 15 SFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTVNIASHIQNDLGVVS 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ HLTC + E++ +E +K G++NVL LRGD P
Sbjct: 75 LAHLTCASSTKEEVHQVIEKLKEKGIENVLGLRGDIP 111
[173][TOP]
>UniRef100_A6NZH7 Methylenetetrahydrofolate reductase n=1 Tax=Bacteroides capillosus
ATCC 29799 RepID=A6NZH7_9BACE
Length = 286
Score = 95.5 bits (236), Expect = 2e-18
Identities = 48/119 (40%), Positives = 70/119 (58%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+ + + +KV SFE FPPKT D ++ + + A P F +T+GAGG
Sbjct: 1 MKIIDILSQ------DKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T+D T+ IA +++ GVE + HLTC + E + L +K +G+ NVLALRGD P G
Sbjct: 55 TSDYTVGIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNVLALRGDIPEG 113
[174][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 94.7 bits (234), Expect = 3e-18
Identities = 50/101 (49%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+E+++HLTC N EKI D L K GL+N++ALRGDP
Sbjct: 120 CGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDP 160
[175][TOP]
>UniRef100_B4S8Y1 Methylenetetrahydrofolate reductase n=1 Tax=Prosthecochloris
aestuarii DSM 271 RepID=B4S8Y1_PROA2
Length = 296
Score = 94.7 bits (234), Expect = 3e-18
Identities = 45/111 (40%), Positives = 65/111 (58%)
Frame = +2
Query: 113 SDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKM 292
S + +FSFEFFPPK D L + ++ +PS+ +T+GAGGST T D+ K+
Sbjct: 8 SSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRTHDLVTKI 67
Query: 293 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
+ G+ + HLTC ++I D L T ++NG+ NVLALRGD P G +
Sbjct: 68 RKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLPPGTTSY 118
[176][TOP]
>UniRef100_B2V845 Methylenetetrahydrofolate reductase n=1 Tax=Sulfurihydrogenibium
sp. YO3AOP1 RepID=B2V845_SULSY
Length = 291
Score = 93.2 bits (230), Expect = 8e-18
Identities = 49/122 (40%), Positives = 70/122 (57%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+K+ KV SFEFFPPKTE+ L E + + +P+F +T+GAGGS
Sbjct: 1 MKIIDKLKNT------KVSISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGS 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T + T DI KK+ + M HLTC ++I L+ + G++N+LALRGD P
Sbjct: 55 TREKTRDIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENILALRGDIPLNF 114
Query: 437 DK 442
+K
Sbjct: 115 EK 116
[177][TOP]
>UniRef100_A6G2Q2 Methylenetetrahydrofolate reductase n=1 Tax=Plesiocystis pacifica
SIR-1 RepID=A6G2Q2_9DELT
Length = 310
Score = 93.2 bits (230), Expect = 8e-18
Identities = 42/105 (40%), Positives = 67/105 (63%)
Frame = +2
Query: 131 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
VFSFEFFPPK E G L ++++ P F +T+GAGGST + T+++ +++ +G+
Sbjct: 13 VFSFEFFPPKHEKGERVLWRSLEQLRTLEPDFVSVTYGAGGSTRERTVELVARIKTELGI 72
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
E M HLTC +++ +E + + + N+LALRGDPP G+ +F
Sbjct: 73 EPMAHLTCVGSTRDELARVVERLLAADVHNILALRGDPPKGETEF 117
[178][TOP]
>UniRef100_A4J6K4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfotomaculum
reducens MI-1 RepID=A4J6K4_DESRM
Length = 288
Score = 92.8 bits (229), Expect = 1e-17
Identities = 42/99 (42%), Positives = 61/99 (61%)
Frame = +2
Query: 131 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
V SFE FPPK+ V + E ++ ++ P F +T+GAGGS+ D T +IA ++N +
Sbjct: 13 VISFEIFPPKSTSPVETIYETLEGLIKLEPGFISVTYGAGGSSRDRTKEIAATIKNRYKI 72
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
E + HLTC V +ID L ++ ++NVLALRGDPP
Sbjct: 73 EALAHLTCVGQAVNEIDQILNELQEENIENVLALRGDPP 111
[179][TOP]
>UniRef100_C1XL88 Methylenetetrahydrofolate reductase n=1 Tax=Meiothermus ruber DSM
1279 RepID=C1XL88_MEIRU
Length = 291
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/107 (42%), Positives = 63/107 (58%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
K +FSFEFFPPKT G L + + P+F IT+GAGGS + T + A ++QN V
Sbjct: 11 KPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTAEWAARIQNEV 70
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
G+ M HLTC E++ L G++N++ALRGDPP G +F
Sbjct: 71 GLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPPQGAREF 117
[180][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 92.8 bits (229), Expect = 1e-17
Identities = 44/103 (42%), Positives = 63/103 (61%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPK E+G L + + + P+F +T+GAGGST D T ++ K++ VG+
Sbjct: 15 SFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTRNVVKRIHEEVGLTV 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
M HLTC E++ + LE + G++N+LALRGD PH F
Sbjct: 75 MAHLTCIAHTREELIEILEDYRGIGIENILALRGDVPHDTPDF 117
[181][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/99 (46%), Positives = 66/99 (66%), Gaps = 1/99 (1%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
+SFEFFPPKTE G+ NLL R+DRM P F D+TWG+ ++A T+ +A Q +GV
Sbjct: 41 YSFEFFPPKTEAGLDNLLTRIDRMAQRLDPLFIDVTWGSDKTSAR-TMALASHAQKYLGV 99
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+ ++HL+C M +++ L+ K G+ N+LALRGDPP
Sbjct: 100 DVLLHLSCQGMTRDQLIRVLDQAKVLGIHNILALRGDPP 138
[182][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/87 (52%), Positives = 62/87 (71%), Gaps = 1/87 (1%)
Frame = +2
Query: 170 GVVNLLERMDRMV-AHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMP 346
G NL +R+DRM A P F ++TWGAGGSTA +L++A+ Q + + T +HLTCTNM
Sbjct: 2 GFSNLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELALTTCLHLTCTNMS 61
Query: 347 VEKIDDALETIKSNGLQNVLALRGDPP 427
+ ID ALE K+ G++N+LALRGDPP
Sbjct: 62 RKLIDKALEDAKALGIRNILALRGDPP 88
[183][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 92.4 bits (228), Expect = 1e-17
Identities = 60/177 (33%), Positives = 86/177 (48%), Gaps = 39/177 (22%)
Frame = +2
Query: 35 SLSLSLASIKD*NKMKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRM-VA 211
S SL A+ + + KI A D +SFEFFPPKT G+ NL R+ RM V
Sbjct: 9 SASLHGATASPSDPAHIATKIQAALTRDAP--FWSFEFFPPKTSQGLANLYNRIARMHVN 66
Query: 212 HSPSFCDITWGAGGSTADVTLDIAKKMQ---------------NTVGVETM--------- 319
PS+ +TWGAGG+T +L++A ++Q N +G T
Sbjct: 67 LEPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQTEINHIGSGTQQHIENVKGG 126
Query: 320 --------------MHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
+HLTCTN+ +D L+T K G++N+LALRGDPP G++ ++
Sbjct: 127 QEWEQERADPCDVCLHLTCTNVEKSSLDQTLDTAKRLGIKNILALRGDPPRGEEYWI 183
[184][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 92.0 bits (227), Expect = 2e-17
Identities = 47/106 (44%), Positives = 61/106 (57%), Gaps = 4/106 (3%)
Frame = +2
Query: 116 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQ 295
+ N FS EFFPP+TE G NL+ R DRM A P F DITW G + + K+
Sbjct: 27 ESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGGPLFVDITWHPAGDPGSDKITSSTKIA 86
Query: 296 NTV----GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 421
TV G++TM+H+TC E I LE K+ G++N+LALRGD
Sbjct: 87 GTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKNLGIRNILALRGD 132
[185][TOP]
>UniRef100_A9KQY7 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
phytofermentans ISDg RepID=A9KQY7_CLOPH
Length = 286
Score = 92.0 bits (227), Expect = 2e-17
Identities = 44/100 (44%), Positives = 62/100 (62%), Gaps = 1/100 (1%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNT 301
K VFS E FPPK + V ++ + + +P F +T+GAGG+ AD T DIA +Q+
Sbjct: 11 KTVFSLEVFPPKKDSPVESIYRVLGELTKLNPDFISVTYGAGGNAADHTTCDIASYIQSN 70
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 421
G++ + HLTC N E +D LE +KS G+ N+LALRGD
Sbjct: 71 YGIDALTHLTCVNSTKEDMDTTLEYLKSQGIMNILALRGD 110
[186][TOP]
>UniRef100_B5CM26 Methylenetetrahydrofolate reductase n=1 Tax=Ruminococcus lactaris
ATCC 29176 RepID=B5CM26_9FIRM
Length = 289
Score = 92.0 bits (227), Expect = 2e-17
Identities = 43/119 (36%), Positives = 73/119 (61%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I++++E +++ SFE FPPKT+ G N+ D + PS+ +T+GAGG
Sbjct: 1 MKIIDRLNE------DRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T+ T IA +++ + V ++ HLTC + E++ + + +K G++N+LALRGD P G
Sbjct: 55 TSKNTAKIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEG 113
[187][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 92.0 bits (227), Expect = 2e-17
Identities = 46/113 (40%), Positives = 71/113 (62%), Gaps = 2/113 (1%)
Frame = +2
Query: 107 AASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIA 283
AA D +K S+E +PP++E ++++ + H SP F D+TWGAGG T+ T+ +
Sbjct: 10 AAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGRTSGTTMRLC 69
Query: 284 KKMQNT-VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
K +Q+ MH+TCTN P I + LE K++G++N+LALRGDPP G++
Sbjct: 70 KDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNILALRGDPPSGEE 122
[188][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 91.7 bits (226), Expect = 2e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 65 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 124
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 125 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDP 165
[189][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 91.7 bits (226), Expect = 2e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNY 159
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDP 200
[190][TOP]
>UniRef100_O67422 5,10-methylenetetrahydrofolate reductase n=1 Tax=Aquifex aeolicus
RepID=METF_AQUAE
Length = 296
Score = 91.7 bits (226), Expect = 2e-17
Identities = 44/97 (45%), Positives = 63/97 (64%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPKTE+G L E + ++ +P+F +T+GAGGST D T +I +K+ +
Sbjct: 15 SFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTRNIVQKIHEETNLTV 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
M HLTC E++ D L+ K+ G++N+LALRGD P
Sbjct: 75 MAHLTCIAHTREELIDILQDYKNIGIENILALRGDVP 111
[191][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 143 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 183
[192][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 161 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 201
[193][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 83 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 142
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 143 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 183
[194][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 101 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 160
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 161 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 201
[195][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[196][TOP]
>UniRef100_B2KFL5 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=B2KFL5_MOUSE
Length = 194
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[197][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[198][TOP]
>UniRef100_A2A7F9 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Mus musculus
RepID=A2A7F9_MOUSE
Length = 194
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[199][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 100 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 159
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 160 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 200
[200][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 120 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 160
[201][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 91.3 bits (225), Expect = 3e-17
Identities = 46/101 (45%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P + D+TW G GS + ++ IA N
Sbjct: 90 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNY 149
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 150 CGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP 190
[202][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N++ALRGDP
Sbjct: 119 CGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDP 159
[203][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 91.3 bits (225), Expect = 3e-17
Identities = 47/101 (46%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T +G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 60 FSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 119
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC +E+I L K GL+N++ALRGDP
Sbjct: 120 CGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDP 160
[204][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 90.9 bits (224), Expect = 4e-17
Identities = 47/101 (46%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNF 113
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC N E I L+ K GL+N++ALRGDP
Sbjct: 114 CGLETLLHMTCCNQTKEDITKHLQKAKRLGLKNIMALRGDP 154
[205][TOP]
>UniRef100_B3QV58 Methylenetetrahydrofolate reductase n=1 Tax=Chloroherpeton
thalassium ATCC 35110 RepID=B3QV58_CHLT3
Length = 294
Score = 90.9 bits (224), Expect = 4e-17
Identities = 41/109 (37%), Positives = 62/109 (56%)
Frame = +2
Query: 119 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 298
P+K FSFEF+PPK ++ L + ++ +P++ +T+GAGGST D T ++ ++
Sbjct: 9 PDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTHNLVVRISK 68
Query: 299 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
+ + HLTC +I LE NG+ N+LALRGDPP G F
Sbjct: 69 ETNIPVVSHLTCVGSSKSEIHTILERYAENGITNILALRGDPPKGSTTF 117
[206][TOP]
>UniRef100_B3E425 Methylenetetrahydrofolate reductase n=1 Tax=Geobacter lovleyi SZ
RepID=B3E425_GEOLS
Length = 290
Score = 90.9 bits (224), Expect = 4e-17
Identities = 41/97 (42%), Positives = 61/97 (62%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S E+FPPK + ++R+ + +P F +T+GAGGS D TL+I +MQ +G+ET
Sbjct: 15 SVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATLEIVTQMQQQLGLET 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
M HLTC +++ L+ + G+QN+LALRGDPP
Sbjct: 75 MAHLTCVGAQAGRLNRFLDDLSKVGIQNILALRGDPP 111
[207][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 90.9 bits (224), Expect = 4e-17
Identities = 43/70 (61%), Positives = 49/70 (70%)
Frame = +2
Query: 218 PSFCDITWGAGGSTADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQ 397
P F DITW AGG T+D+T + K +Q GVET MHLTCTNMP KI+ AL K G +
Sbjct: 6 PEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAKEFGCR 65
Query: 398 NVLALRGDPP 427
NVLALRGDPP
Sbjct: 66 NVLALRGDPP 75
[208][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDP 164
[209][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC + E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDP 159
[210][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDP 164
[211][TOP]
>UniRef100_C4XPB4 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
magneticus RS-1 RepID=C4XPB4_DESMR
Length = 330
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/104 (42%), Positives = 61/104 (58%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S EFFPPK + +++++ P F +T+GAGGST TL+I +++ G+E
Sbjct: 55 SLEFFPPKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTLEIVSRLKTAYGLEP 114
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
M HLTC +KI L + G+ NVLALRGDPP GQ+ FV
Sbjct: 115 MAHLTCVGASKDKIRGFLGALAQAGVDNVLALRGDPPKGQETFV 158
[212][TOP]
>UniRef100_A1BH63 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides DSM 266 RepID=A1BH63_CHLPD
Length = 289
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/101 (43%), Positives = 59/101 (58%)
Frame = +2
Query: 131 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
VFSFEFFPPK E+ L + + + +PS+ +T+GAGGST T D+ ++Q G+
Sbjct: 14 VFSFEFFPPKKEEEWNTLFATIASLTSLNPSYVSVTYGAGGSTRSKTHDLVTRIQKETGI 73
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+ HLTC E+ LE NG+ NVLALRGD P G
Sbjct: 74 TVVSHLTCVCSDREETSSILENYLENGINNVLALRGDKPQG 114
[213][TOP]
>UniRef100_A3ZZ23 Methylenetetrahydrofolate reductase n=1 Tax=Blastopirellula marina
DSM 3645 RepID=A3ZZ23_9PLAN
Length = 293
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/109 (40%), Positives = 64/109 (58%)
Frame = +2
Query: 119 PNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQN 298
P ++ SFE FPPKT+ G +L+ ++++V P + T+GAGGST TLDI +K++
Sbjct: 9 PGRLGLSFELFPPKTDKGDASLMLHVEKLVKFKPDYITCTYGAGGSTRGKTLDIVEKVKQ 68
Query: 299 TVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
GV HLT + V + L + G+ ++ALRGDPP GQ KF
Sbjct: 69 VFGVPVASHLTLVDSTVGDLRLYLAEAERRGVDYIVALRGDPPQGQTKF 117
[214][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 90.5 bits (223), Expect = 5e-17
Identities = 45/100 (45%), Positives = 61/100 (61%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKTE G + L D + A +P F +T+GAGGST D TL+ + G+
Sbjct: 40 FSFEFFPPKTEQGKIKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETVFSLHQQ-GIS 98
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T HL+C +I + L+T K+NG+ ++ALRGD P G
Sbjct: 99 TAPHLSCVGGTRAEISELLDTYKANGINRIVALRGDLPSG 138
[215][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 90.5 bits (223), Expect = 5e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC + E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDP 159
[216][TOP]
>UniRef100_C0QT51 Methylenetetrahydrofolate reductase n=1 Tax=Persephonella marina
EX-H1 RepID=C0QT51_PERMH
Length = 293
Score = 90.1 bits (222), Expect = 7e-17
Identities = 43/102 (42%), Positives = 63/102 (61%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPKT +G L + + +P+F +T+GAGGST + T+ + K++ +
Sbjct: 15 SFEFFPPKTPEGEDQLFRTIKDLEKLNPTFVSVTYGAGGSTRERTIRVVKRIHEQCNLTV 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDK 442
M HLTC ++I D L+ K G+QN+LALRGD P GQ++
Sbjct: 75 MAHLTCIGHSKKEIYDILKGYKDIGIQNILALRGDIPQGQEE 116
[217][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 90.1 bits (222), Expect = 7e-17
Identities = 43/88 (48%), Positives = 60/88 (68%), Gaps = 2/88 (2%)
Frame = +2
Query: 170 GVVNLLERMDRMVAHSPSFCDITWGAGG--STADVTLDIAKKMQNTVGVETMMHLTCTNM 343
GV NL ER+DRM P + D+TWGAGG S+++ T +I + G++ MMHLTCT+
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTHQ 61
Query: 344 PVEKIDDALETIKSNGLQNVLALRGDPP 427
VE+ID+ L+ K G++N+LALRGD P
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAP 89
[218][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC N E I L K GL+N++ALRGDP
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDP 154
[219][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 89.7 bits (221), Expect = 9e-17
Identities = 48/101 (47%), Positives = 62/101 (61%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM + P F DITW G GS + ++ IA N
Sbjct: 64 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY 123
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+E+++HLTC N +KI L K GL+N++ALRGDP
Sbjct: 124 CGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDP 164
[220][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R DRM + P F D+TW G GS + ++ IA N
Sbjct: 54 FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNF 113
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC N E I L K GL+N++ALRGDP
Sbjct: 114 CGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDP 154
[221][TOP]
>UniRef100_C1FN88 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
A2 str. Kyoto RepID=C1FN88_CLOBJ
Length = 295
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/116 (36%), Positives = 69/116 (59%), Gaps = 1/116 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P +D
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKD 116
[222][TOP]
>UniRef100_B1L1W9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
A3 str. Loch Maree RepID=B1L1W9_CLOBM
Length = 295
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/116 (36%), Positives = 68/116 (58%), Gaps = 1/116 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FP K + + E ++ + +P F +T+GAGGS D T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPSKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P +D
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKD 116
[223][TOP]
>UniRef100_A5I291 Methylenetetrahydrofolate reductase n=2 Tax=Clostridium botulinum A
RepID=A5I291_CLOBH
Length = 295
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/116 (36%), Positives = 69/116 (59%), Gaps = 1/116 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P +D
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKD 116
[224][TOP]
>UniRef100_Q0YRM1 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium ferrooxidans
DSM 13031 RepID=Q0YRM1_9CHLB
Length = 328
Score = 89.7 bits (221), Expect = 9e-17
Identities = 47/117 (40%), Positives = 69/117 (58%)
Frame = +2
Query: 83 VIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA 262
++++I +AA K VFSFEFFPPK ++ L + + + +PS+ +T+GAGGST
Sbjct: 41 LVKEILDAAV----KPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTR 96
Query: 263 DVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T D+ K+Q G+ + HLTC E+ L+ + NG+ NVLALRGD P G
Sbjct: 97 SRTHDLVTKIQRETGLTVVSHLTCICSDREETGSILQNYRDNGINNVLALRGDKPAG 153
[225][TOP]
>UniRef100_C1SKU9 Methylenetetrahydrofolate reductase n=1 Tax=Denitrovibrio
acetiphilus DSM 12809 RepID=C1SKU9_9BACT
Length = 284
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/103 (40%), Positives = 62/103 (60%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPK ++ L E + ++ ++P F +T+GAGGST + TL+ K+M+
Sbjct: 14 SFEFFPPKKQESEQVLFETIKKLRRYNPEFVSVTYGAGGSTTEKTLEWTKRMKEDHDYSV 73
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
MMH TC ID A +++K + + N+LALRGD P G +F
Sbjct: 74 MMHFTCIGADAAVIDSATQSLKESRVDNILALRGDIPAGTTEF 116
[226][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 89.7 bits (221), Expect = 9e-17
Identities = 43/88 (48%), Positives = 59/88 (67%), Gaps = 2/88 (2%)
Frame = +2
Query: 170 GVVNLLERMDRMVAHSPSFCDITWGAGGSTA--DVTLDIAKKMQNTVGVETMMHLTCTNM 343
GV NL ER+DRM P + D+TWGAGGS++ + T +I + G++ MMHLTCT
Sbjct: 2 GVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQQ 61
Query: 344 PVEKIDDALETIKSNGLQNVLALRGDPP 427
VE+ID+ L+ K G++N+LALRGD P
Sbjct: 62 SVEEIDEVLDKCKEVGIRNILALRGDAP 89
[227][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 89.4 bits (220), Expect = 1e-16
Identities = 43/100 (43%), Positives = 60/100 (60%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKT +G+ L D++ P F +T+GAGGST + T+D + G+
Sbjct: 11 FSFEFFPPKTPEGMEKLQVVRDKLAKRKPDFFSVTYGAGGSTRERTIDTVLTLHRQ-GIS 69
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
T HL+C E I + L+ +SNG+Q ++ALRGD P G
Sbjct: 70 TAPHLSCIGATKESIGELLDLYRSNGIQRIVALRGDLPSG 109
[228][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 89.4 bits (220), Expect = 1e-16
Identities = 43/101 (42%), Positives = 61/101 (60%)
Frame = +2
Query: 131 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
VFSFEFFPPKT++G L + + + P F +T+GAGGST TLD ++Q
Sbjct: 10 VFSFEFFPPKTDEGAEKLRKAREALAELKPKFFSVTYGAGGSTQARTLDTVLEIQRDARF 69
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
E HL+C E I + LE ++NG+++++ALRGD P G
Sbjct: 70 EAAPHLSCIGSTREHIREILELYRNNGIRHIVALRGDMPSG 110
[229][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 89.4 bits (220), Expect = 1e-16
Identities = 50/126 (39%), Positives = 70/126 (55%), Gaps = 5/126 (3%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
+K+ ++I A D + FS EFFPP+T G NL+ R +RMV P F DITW G
Sbjct: 30 VKLADRIE--AKIDRGERWFSLEFFPPRTPQGAANLISRFERMVQGGPMFMDITWHPAGD 87
Query: 257 TAD-----VTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 421
+ ++ IA N VG ETM+H++C N + I L+ K G++N+LALRGD
Sbjct: 88 PGNSDKETSSMSIACAALNYVGHETMLHMSCCNSTKDDIRRHLDKAKELGIRNILALRGD 147
Query: 422 PPHGQD 439
P G +
Sbjct: 148 PIVGDE 153
[230][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 89.4 bits (220), Expect = 1e-16
Identities = 49/140 (35%), Positives = 78/140 (55%), Gaps = 17/140 (12%)
Frame = +2
Query: 80 KVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMV-AHSPSFCDITWGAGGS 256
++ EK+++ S + V+S EFFPP+T G+ NL R+ RM A P + +TWG GGS
Sbjct: 11 RIDEKLND---STQDAYVWSLEFFPPRTALGLANLCARVARMSEALQPGWVHVTWGTGGS 67
Query: 257 TADVTLDIAKKMQNTV----------------GVETMMHLTCTNMPVEKIDDALETIKSN 388
T D ++++A ++Q V + +HLTCTN+ +D L+ +
Sbjct: 68 TRDASMELAARVQKGVYDPLEDYTNVKERRKGACDVCLHLTCTNVERAYLDATLDEARQI 127
Query: 389 GLQNVLALRGDPPHGQDKFV 448
G++N+LALRGDPP + +V
Sbjct: 128 GIRNILALRGDPPRSDEYWV 147
[231][TOP]
>UniRef100_UPI0001794577 hypothetical protein CLOSPO_03313 n=1 Tax=Clostridium sporogenes
ATCC 15579 RepID=UPI0001794577
Length = 336
Score = 89.0 bits (219), Expect = 2e-16
Identities = 42/113 (37%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = +2
Query: 92 KIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-V 268
++H + +VFSFE FPPK V + E ++ + +P F +T+GAGGS D
Sbjct: 41 RMHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNK 100
Query: 269 TLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
T +++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 101 TCELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIP 153
[232][TOP]
>UniRef100_C6BWS6 Methylenetetrahydrofolate reductase n=1 Tax=Desulfovibrio
salexigens DSM 2638 RepID=C6BWS6_DESAD
Length = 290
Score = 89.0 bits (219), Expect = 2e-16
Identities = 44/123 (35%), Positives = 68/123 (55%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGS 256
MK+I+ I++ N S EFFPPK + E +D++ +P F +T+GAGG
Sbjct: 1 MKIIDLINK------NGQFISLEFFPPKDRESWPKFFEVVDKLKVLNPLFASVTYGAGGG 54
Query: 257 TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ 436
T D +L+I K+M+ G+E + HLTC E I + + ++ ++N+LALRGD P
Sbjct: 55 TQDNSLEIVKRMKQDAGIEPLAHLTCVGASPENISEFVSALQEADVENILALRGDAPADD 114
Query: 437 DKF 445
F
Sbjct: 115 KDF 117
[233][TOP]
>UniRef100_B2UWX9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
E3 str. Alaska E43 RepID=B2UWX9_CLOBA
Length = 292
Score = 89.0 bits (219), Expect = 2e-16
Identities = 40/104 (38%), Positives = 66/104 (63%), Gaps = 1/104 (0%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADV-TLDIAKKMQNT 301
KVVFSFE FPPKT + + + +D + +P + +T+GAGGS + T++++ ++N
Sbjct: 11 KVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNTIELSSLIKNK 70
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
G+E + HLTC N+ + ++ L + N ++N+LALRGD P G
Sbjct: 71 YGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIG 114
[234][TOP]
>UniRef100_C7IBI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Clostridium
papyrosolvens DSM 2782 RepID=C7IBI3_9CLOT
Length = 286
Score = 89.0 bits (219), Expect = 2e-16
Identities = 42/100 (42%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VTLDIAKKMQNT 301
K V SFE FPPK + + ++ E + + SP F +T+GAGGS+ + T++IAKK+++
Sbjct: 11 KPVLSFEIFPPKRDSELKDIDETLAILSKLSPDFISVTFGAGGSSNNNKTIEIAKKIKHQ 70
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD 421
G+ET++HLTC+ ++ID + + NG++N+LALRGD
Sbjct: 71 YGIETLVHLTCSGYTKQEIDSFISILSENGIENILALRGD 110
[235][TOP]
>UniRef100_C0FIZ9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp. M62/1
RepID=C0FIZ9_9CLOT
Length = 287
Score = 89.0 bits (219), Expect = 2e-16
Identities = 45/103 (43%), Positives = 63/103 (61%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
K SFE FPPK ED ++ E R+ P+F +T+GAGG T+ T+DIA ++N
Sbjct: 11 KPTLSFEVFPPKAEDKYDSVEEAAIRIARLKPAFMSVTYGAGGGTSKYTVDIASSIKNQ- 69
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
GV + HLTC + E++ L +K+ G++NVLALRGD P G
Sbjct: 70 GVNALAHLTCVSSTKEEVRRVLGELKTRGIENVLALRGDIPEG 112
[236][TOP]
>UniRef100_A8TTR8 Methylenetetrahydrofolate reductase n=1 Tax=alpha proteobacterium
BAL199 RepID=A8TTR8_9PROT
Length = 288
Score = 89.0 bits (219), Expect = 2e-16
Identities = 41/99 (41%), Positives = 60/99 (60%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFPPK E G + L E +DR+ + P F +T+GAGGST + T I +++ G+E
Sbjct: 8 SFEFFPPKDEAGEIKLWETLDRLAPYGPRFVSVTYGAGGSTRERTSRIVTRIKRETGLEP 67
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
HLTC +++D+ G+++V+ALRGD P G
Sbjct: 68 AAHLTCVGATCDEVDEVARGWWDAGIRHVVALRGDAPAG 106
[237][TOP]
>UniRef100_A4SE12 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeovibrioides DSM 265 RepID=A4SE12_PROVI
Length = 289
Score = 88.6 bits (218), Expect = 2e-16
Identities = 44/106 (41%), Positives = 63/106 (59%)
Frame = +2
Query: 122 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 301
+K VFSFEFFPPK + L E + + +PS+ +T+GAGGST T D+ ++Q
Sbjct: 11 HKPVFSFEFFPPKKDADWETLFETITALSPLNPSYVSVTYGAGGSTRTRTHDLVTRIQKE 70
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQD 439
G+ + HLTC + + LE +S+G+ NVLALRGD P G +
Sbjct: 71 TGLSVVSHLTCIASTSGETGEILENYQSHGINNVLALRGDKPTGTE 116
[238][TOP]
>UniRef100_C6JIG2 Methylenetetrahydrofolate reductase n=1 Tax=Fusobacterium varium
ATCC 27725 RepID=C6JIG2_FUSVA
Length = 293
Score = 88.6 bits (218), Expect = 2e-16
Identities = 39/101 (38%), Positives = 63/101 (62%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTV 304
K + SFE FPP + + ++ +D + P F +T+GAGG+T T++IA K++N
Sbjct: 11 KTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTVEIASKIKNNN 70
Query: 305 GVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+E + HLTC +IDD L+ +++N ++N+LALRGD P
Sbjct: 71 KIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKP 111
[239][TOP]
>UniRef100_C5RR04 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium
cellulovorans 743B RepID=C5RR04_CLOCL
Length = 285
Score = 88.6 bits (218), Expect = 2e-16
Identities = 41/102 (40%), Positives = 63/102 (61%)
Frame = +2
Query: 122 NKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNT 301
N+ FS E FPPK D N++ +D + F +T+GAGGS+ D T+ ++KK+++
Sbjct: 9 NRQSFSVELFPPKKTDSFDNIINTLDNLNGLDIDFVSVTYGAGGSSRDNTVKLSKKIKSE 68
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+E + HLTC N ++I L+ +K N L+N+LALRGD P
Sbjct: 69 YNLEVITHLTCINSKKDEIASLLDEMKENNLENILALRGDIP 110
[240][TOP]
>UniRef100_C1I310 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium sp.
7_2_43FAA RepID=C1I310_9CLOT
Length = 297
Score = 88.6 bits (218), Expect = 2e-16
Identities = 41/107 (38%), Positives = 67/107 (62%), Gaps = 1/107 (0%)
Frame = +2
Query: 116 DPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTA-DVTLDIAKKM 292
D +VVFSFE FPPK E + + ++ + P F +T+GAGGS + ++T +I+ +
Sbjct: 8 DKKEVVFSFEIFPPKQESKIDTIYNTLEELKDLKPDFISVTYGAGGSLSKNMTCEISSIV 67
Query: 293 QNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+N +E + HLTC N +++ L+ +K +G++N+LALRGD P G
Sbjct: 68 KNKYKIEPLAHLTCINSNKNQVNSILDNLKQSGIENILALRGDIPLG 114
[241][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 88.2 bits (217), Expect = 3e-16
Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITW---GAGGSTADV-TLDIAKKMQNT 301
FS EFFPP+T G VNL+ R D+M A P F D+TW G GS + ++ IA N
Sbjct: 59 FSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY 118
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDP 424
G+ET++H+TC E+I L K GL+N+LALRGDP
Sbjct: 119 CGLETVLHMTCCRQSREEITGYLHKAKRLGLKNILALRGDP 159
[242][TOP]
>UniRef100_B3EPY8 Methylenetetrahydrofolate reductase n=1 Tax=Chlorobium
phaeobacteroides BS1 RepID=B3EPY8_CHLPB
Length = 293
Score = 88.2 bits (217), Expect = 3e-16
Identities = 42/105 (40%), Positives = 61/105 (58%)
Frame = +2
Query: 131 VFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGV 310
VFSFEFFPPK + L + ++ +PS+ +T+GAGGST T D+ K+Q G+
Sbjct: 14 VFSFEFFPPKKTEDWGKLFHTISELIPFNPSYVSVTYGAGGSTRSRTHDLVTKIQRETGL 73
Query: 311 ETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKF 445
+ HLTC + + + LE ++ G+ NVLALRGD P G +
Sbjct: 74 TVVSHLTCICSGKKDVAEILEDYRTQGITNVLALRGDLPPGSTSY 118
[243][TOP]
>UniRef100_B1ILP1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
B1 str. Okra RepID=B1ILP1_CLOBK
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[244][TOP]
>UniRef100_A7GDU9 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum F
str. Langeland RepID=A7GDU9_CLOBL
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[245][TOP]
>UniRef100_C5EJM1 Methylenetetrahydrofolate reductase n=1 Tax=Clostridiales bacterium
1_7_47FAA RepID=C5EJM1_9FIRM
Length = 292
Score = 88.2 bits (217), Expect = 3e-16
Identities = 48/106 (45%), Positives = 69/106 (65%), Gaps = 2/106 (1%)
Frame = +2
Query: 125 KVVFSFEFFPPKTEDGVVNLLERMDRMVAH-SPSFCDITWGAGGSTADVTLDIAKKMQNT 301
K SFE FPPKTED N +E+ + +A P+F +T+GAGG T+D T+ IA ++
Sbjct: 11 KPTLSFEVFPPKTEDN-YNTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTVGIASDIKE- 68
Query: 302 VGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGD-PPHGQ 436
GV + HLTC + EK+ L+ +K++G++NVLALRGD P +GQ
Sbjct: 69 YGVTPLAHLTCVSSTREKVQGVLKELKAHGIENVLALRGDIPENGQ 114
[246][TOP]
>UniRef100_B1QD70 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium botulinum
NCTC 2916 RepID=B1QD70_CLOBO
Length = 295
Score = 88.2 bits (217), Expect = 3e-16
Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = +2
Query: 95 IHEAAASDPNKVVFSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTAD-VT 271
+H + K+VFSFE FPPK + + E ++ + +P F +T+GAGGS + T
Sbjct: 1 MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT 60
Query: 272 LDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPP 427
+++ ++N G+E + HLTC N + ID ++ +K N ++N+LALRGD P
Sbjct: 61 CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIP 112
[247][TOP]
>UniRef100_B1C148 Methylenetetrahydrofolate reductase n=1 Tax=Clostridium spiroforme
DSM 1552 RepID=B1C148_9FIRM
Length = 296
Score = 88.2 bits (217), Expect = 3e-16
Identities = 42/122 (34%), Positives = 73/122 (59%), Gaps = 1/122 (0%)
Frame = +2
Query: 77 MKVIEKIHEAAASDPNKVVFSFEFFPPKTEDG-VVNLLERMDRMVAHSPSFCDITWGAGG 253
MK+I+ +H+ + SFE FPPK DG + ++ + +D + P F +T+GAGG
Sbjct: 1 MKIIDLLHK-------RPTLSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGG 53
Query: 254 STADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
ST T++IA K++N +E + HL+C + +++ ++ +K N ++N+L+LRGD P
Sbjct: 54 STTKNTVEIASKIKNDYNIEAVAHLSCIDASPKQLIKIIDALKENKIENILSLRGDYPKD 113
Query: 434 QD 439
D
Sbjct: 114 YD 115
[248][TOP]
>UniRef100_A6C2T8 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces maris DSM
8797 RepID=A6C2T8_9PLAN
Length = 297
Score = 88.2 bits (217), Expect = 3e-16
Identities = 40/104 (38%), Positives = 62/104 (59%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
S E FPP+ E G L + ++ +V + P+F T+GAGGST+ T+++ +QN +
Sbjct: 15 SVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTIELCALIQNQLHNTA 74
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQDKFV 448
H TC N E++ + L+ G+ N++ALRGDPP GQ+ FV
Sbjct: 75 TAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFV 118
[249][TOP]
>UniRef100_UPI0001744B57 5,10-methylenetetrahydrofolate reductase n=1 Tax=Verrucomicrobium
spinosum DSM 4136 RepID=UPI0001744B57
Length = 300
Score = 87.8 bits (216), Expect = 3e-16
Identities = 42/100 (42%), Positives = 59/100 (59%)
Frame = +2
Query: 134 FSFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVE 313
FSFEFFPPKT + L E + + A P F +T+GAGG+T ++T D+ +++ T ++
Sbjct: 14 FSFEFFPPKTAETSQALYETISELEAFKPDFVSVTYGAGGTTRELTHDLVVRIKQTTSLD 73
Query: 314 TMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
+ HLTC E I LE G+ N+LAL GDPP G
Sbjct: 74 PIPHLTCVCHSEEDIGGILERYAEAGVSNILALGGDPPRG 113
[250][TOP]
>UniRef100_Q1MYH5 Methylenetetrahydrofolate reductase n=1 Tax=Bermanella marisrubri
RepID=Q1MYH5_9GAMM
Length = 278
Score = 87.8 bits (216), Expect = 3e-16
Identities = 44/99 (44%), Positives = 59/99 (59%)
Frame = +2
Query: 137 SFEFFPPKTEDGVVNLLERMDRMVAHSPSFCDITWGAGGSTADVTLDIAKKMQNTVGVET 316
SFEFFP KTE+G L D++ P F +T+GAGGST D T+D+ KM N +GV T
Sbjct: 7 SFEFFPTKTEEGTKKLYATRDKLAELKPDFFSVTFGAGGSTRDHTMDVVTKM-NGMGVGT 65
Query: 317 MMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHG 433
HL+C ++I L T N ++ ++ALRGD P G
Sbjct: 66 APHLSCIGQSKDEIKQLLSTYADNKVERIVALRGDLPSG 104