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[1][TOP]
>UniRef100_Q9FVE2 Uricase n=1 Tax=Chlamydomonas reinhardtii RepID=Q9FVE2_CHLRE
Length = 295
Score = 319 bits (817), Expect = 9e-86
Identities = 154/155 (99%), Positives = 154/155 (99%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
MATYALPLHHHGKSKVRLGRVWRDG VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT
Sbjct: 1 MATYALPLHHHGKSKVRLGRVWRDGTVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH
Sbjct: 61 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 120
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK
Sbjct: 121 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 155
[2][TOP]
>UniRef100_A8IJT8 Uricase n=1 Tax=Chlamydomonas reinhardtii RepID=A8IJT8_CHLRE
Length = 208
Score = 307 bits (787), Expect = 3e-82
Identities = 147/147 (100%), Positives = 147/147 (100%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT
Sbjct: 1 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH
Sbjct: 61 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 120
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAG 501
GFALQGTEVRTVYVTYDKAGTLDVTAG
Sbjct: 121 GFALQGTEVRTVYVTYDKAGTLDVTAG 147
[3][TOP]
>UniRef100_C1EID1 Uricase n=1 Tax=Micromonas sp. RCC299 RepID=C1EID1_9CHLO
Length = 295
Score = 144 bits (364), Expect = 3e-33
Identities = 65/147 (44%), Positives = 92/147 (62%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
H HGK +VR+ R WR+G++HH VEWNV +I+S M HA+ N GMT TDT KN YVV
Sbjct: 7 HVHGKKRVRVARTWREGSMHHFVEWNVEVVIESAMAHAYKTPSNEGMTTTDTTKNQCYVV 66
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ M ++C+ E+YA+AL + FV +YPL+S ++ VEQ PW R + G HDHG+
Sbjct: 67 AKAMQKRCSPEEYALALGKQFVDSYPLISAVEVRVEQAPWRRTRVHGADHDHGYTFTAPC 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+R + V +G++ L +LK
Sbjct: 127 LRVCAAVVSRTKPPAVRSGMRHLRVLK 153
[4][TOP]
>UniRef100_A2SXR3 Uricase n=1 Tax=Solanum lycopersicum RepID=A2SXR3_SOLLC
Length = 307
Score = 141 bits (356), Expect = 2e-32
Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN-VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGKS+VR+ RVWRD + HH EW+VN + SD A+++GDN+ + ATDT KNTVY A
Sbjct: 13 HGKSRVRVARVWRDRDGKHHFAEWSVNISLISDCLPAYVSGDNSDIVATDTMKNTVYAKA 72
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S+K + E +AI LA+HF Y V+ A + + +KPW R+ G H+HGF L G+E
Sbjct: 73 KECSEKLSAEDFAIVLAKHFTSFYQQVTAAIVNIVEKPWERISIKGQQHEHGFKL-GSER 131
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V DK+GTL +T+G++ LS+LK
Sbjct: 132 HTTEVMVDKSGTLHLTSGIEGLSILK 157
[5][TOP]
>UniRef100_A2SXR5 Uricase n=1 Tax=Solanum tuberosum RepID=A2SXR5_SOLTU
Length = 307
Score = 141 bits (355), Expect = 3e-32
Identities = 70/146 (47%), Positives = 99/146 (67%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN-VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGKS+VR+ RVWRD + HH VEW+VN + SD A+++GDN+ + ATDT KNTVY A
Sbjct: 13 HGKSRVRVARVWRDRDGKHHFVEWSVNISLISDCLPAYVSGDNSDIVATDTMKNTVYAKA 72
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S++ + E +AI LA+HF Y V+ A + + +KPW R+ G H+HGF L G+E
Sbjct: 73 KECSEQLSAEDFAIVLAKHFTSFYQQVTAAIVNIVEKPWERISIKGQQHEHGFKL-GSER 131
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V DK+GTL +T+G++ LS+LK
Sbjct: 132 HTTEVMVDKSGTLRLTSGIEGLSILK 157
[6][TOP]
>UniRef100_A2SXR6 Uricase n=1 Tax=Pinus taeda RepID=A2SXR6_PINTA
Length = 295
Score = 137 bits (346), Expect = 4e-31
Identities = 65/145 (44%), Positives = 93/145 (64%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
HGK++VR+ R WR +VEWNVN M+ S+ A+ NGDN+ + ATD+ KNTVY A+
Sbjct: 11 HGKARVRVARAWRQSGKQWIVEWNVNIMLYSECLAAYTNGDNSDIVATDSMKNTVYAKAK 70
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ +E + I L +HF+ TY V+ I + +KPW RV G+PH+HGF L GTE
Sbjct: 71 ECADHVPVEDFGILLGKHFIATYSQVTAVTIKIVEKPWERVWIDGIPHEHGFKL-GTEKH 129
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
TV + +K G + VT+G++ L+LLK
Sbjct: 130 TVEININKGGDVKVTSGVEGLALLK 154
[7][TOP]
>UniRef100_B9HVK0 Uricase n=1 Tax=Populus trichocarpa RepID=B9HVK0_POPTR
Length = 308
Score = 137 bits (345), Expect = 5e-31
Identities = 67/147 (45%), Positives = 101/147 (68%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD--GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK++VR+ RVWR+ ++H MVEW V+ ++ SD ++++ DN+ + ATDT KNTVYV
Sbjct: 14 HGKARVRVARVWRNKSDHIHSMVEWGVSIILLSDCVNSYVRDDNSDIVATDTMKNTVYVK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S++ + E +AI LA+HF Y V+ A + + +KPW RV +G PH+HGF L G+E
Sbjct: 74 AKECSEQLSAENFAILLARHFTSFYKQVTTAIVKIVEKPWERVHINGQPHEHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T VT K+G L +T+G++ LS+LK
Sbjct: 133 KHTAEVTVQKSGVLKLTSGIEGLSVLK 159
[8][TOP]
>UniRef100_A9PGD8 Uricase n=1 Tax=Populus trichocarpa RepID=A9PGD8_POPTR
Length = 308
Score = 137 bits (345), Expect = 5e-31
Identities = 67/147 (45%), Positives = 101/147 (68%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD--GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK++VR+ RVWR+ ++H MVEW V+ ++ SD ++++ DN+ + ATDT KNTVYV
Sbjct: 14 HGKARVRVARVWRNKSDHIHSMVEWGVSIILLSDCVNSYVRDDNSDIVATDTMKNTVYVK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S++ + E +AI LA+HF Y V+ A + + +KPW RV +G PH+HGF L G+E
Sbjct: 74 AKECSEQLSAENFAILLARHFTSFYKQVTTAIVKIVEKPWERVHINGQPHEHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T VT K+G L +T+G++ LS+LK
Sbjct: 133 KHTAEVTVQKSGVLKLTSGIEGLSVLK 159
[9][TOP]
>UniRef100_A9TDH8 Uricase n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9TDH8_PHYPA
Length = 303
Score = 137 bits (344), Expect = 6e-31
Identities = 68/150 (45%), Positives = 100/150 (66%), Gaps = 3/150 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVY 258
H HGK+KVR+GR+WR H VEWNV+ I S + AF +GDN+ + ATD+ KNT+Y
Sbjct: 8 HQHGKAKVRVGRLWRGATSQEHRFVEWNVSVSITSFVLPAFTDGDNSKIVATDSIKNTIY 67
Query: 259 VVAQRMSQKCTIEQYAIALAQHFVRTYP-LVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
+A++ +++ ++E + + + QHF+RTYP +V+ AK+ + QKPW RV G+ H+HGF L
Sbjct: 68 YLAKQCTEELSLEDFGVVVGQHFLRTYPKIVTGAKVILSQKPWERVVVDGVEHNHGFKL- 126
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G+ T V G + VT+G+ DLSLLK
Sbjct: 127 GSGKHTAEVIIGSNGCVKVTSGITDLSLLK 156
[10][TOP]
>UniRef100_A2SXS1 Uricase n=1 Tax=Physcomitrella patens subsp. patens
RepID=A2SXS1_PHYPA
Length = 297
Score = 137 bits (344), Expect = 6e-31
Identities = 68/150 (45%), Positives = 100/150 (66%), Gaps = 3/150 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVY 258
H HGK+KVR+GR+WR H VEWNV+ I S + AF +GDN+ + ATD+ KNT+Y
Sbjct: 8 HQHGKAKVRVGRLWRGATSQEHRFVEWNVSVSITSFVLPAFTDGDNSKIVATDSIKNTIY 67
Query: 259 VVAQRMSQKCTIEQYAIALAQHFVRTYP-LVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
+A++ +++ ++E + + + QHF+RTYP +V+ AK+ + QKPW RV G+ H+HGF L
Sbjct: 68 YLAKQCTEELSLEDFGVVVGQHFLRTYPKIVTGAKVILSQKPWERVVVDGVEHNHGFKL- 126
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G+ T V G + VT+G+ DLSLLK
Sbjct: 127 GSGKHTAEVIIGSNGCVKVTSGITDLSLLK 156
[11][TOP]
>UniRef100_UPI0001985A0D PREDICTED: urate oxidase n=1 Tax=Vitis vinifera RepID=UPI0001985A0D
Length = 309
Score = 134 bits (338), Expect = 3e-30
Identities = 67/146 (45%), Positives = 99/146 (67%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHM-VEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK++VRLGRVWR + H+ VEW V+ + S+ A++ DN+ + ATD+ KNTVY A
Sbjct: 15 HGKARVRLGRVWRSQSGRHIFVEWTVSISLLSNCLAAYVRDDNSDIVATDSMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ +Q+ ++E++AI LA+HF Y V+ A + VE+KPW R G PHDHGF +G+E+
Sbjct: 75 KECAQQLSMEEFAIKLAKHFTSFYQQVTTAIVTVEEKPWERAYIDGQPHDHGFK-RGSEM 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V +K+G L VT+G++ L+LLK
Sbjct: 134 HTTEVIVEKSGALQVTSGIQGLALLK 159
[12][TOP]
>UniRef100_A7QHU4 Uricase n=1 Tax=Vitis vinifera RepID=A7QHU4_VITVI
Length = 295
Score = 134 bits (338), Expect = 3e-30
Identities = 67/146 (45%), Positives = 99/146 (67%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHM-VEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK++VRLGRVWR + H+ VEW V+ + S+ A++ DN+ + ATD+ KNTVY A
Sbjct: 15 HGKARVRLGRVWRSQSGRHIFVEWTVSISLLSNCLAAYVRDDNSDIVATDSMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ +Q+ ++E++AI LA+HF Y V+ A + VE+KPW R G PHDHGF +G+E+
Sbjct: 75 KECAQQLSMEEFAIKLAKHFTSFYQQVTTAIVTVEEKPWERAYIDGQPHDHGFK-RGSEM 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V +K+G L VT+G++ L+LLK
Sbjct: 134 HTTEVIVEKSGALQVTSGIQGLALLK 159
[13][TOP]
>UniRef100_A2SXS2 Uricase n=1 Tax=Vitis vinifera RepID=A2SXS2_VITVI
Length = 309
Score = 134 bits (337), Expect = 4e-30
Identities = 67/146 (45%), Positives = 98/146 (67%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHM-VEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK++VRLGRVWR + H+ VEW V+ + S+ A++ DN+ + ATD+ KNTVY A
Sbjct: 15 HGKARVRLGRVWRSQSGRHIFVEWTVSISLLSNCLAAYVRDDNSDIVATDSMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ +Q+ ++E++AI LA+HF Y V+ A + VE+KPW R G PHDHGF +G+E
Sbjct: 75 KECAQQLSMEEFAIKLAKHFTSFYQQVTTAIVTVEEKPWERAYIDGQPHDHGFK-RGSET 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V +K+G L VT+G++ L+LLK
Sbjct: 134 HTTEVIVEKSGALQVTSGIQGLALLK 159
[14][TOP]
>UniRef100_A5BG76 Uricase n=1 Tax=Vitis vinifera RepID=A5BG76_VITVI
Length = 309
Score = 134 bits (336), Expect = 5e-30
Identities = 67/146 (45%), Positives = 97/146 (66%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHH-MVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK++VRLGRVWR + H VEW V+ + S+ A++ DN+ + ATD+ KNTVY A
Sbjct: 15 HGKARVRLGRVWRSQSGRHXFVEWTVSISLLSNCLAAYVRDDNSDIVATDSMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ +Q+ ++E++AI LA+HF Y V+ A + VE+KPW R G PHDHGF +G+E
Sbjct: 75 KECAQQLSMEEFAIKLAKHFTSFYQQVTTAIVTVEEKPWERAYIDGQPHDHGFK-RGSET 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V +K+G L VT+G++ L+LLK
Sbjct: 134 HTTEVIVEKSGALQVTSGIQGLALLK 159
[15][TOP]
>UniRef100_Q9FRY6 Uricase n=1 Tax=Lotus japonicus RepID=Q9FRY6_LOTJA
Length = 307
Score = 132 bits (331), Expect = 2e-29
Identities = 65/146 (44%), Positives = 94/146 (64%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHH-MVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK +VR+ RVW++ HH +VEW V+ + SD +++L DN+ + ATDT KNTVY A
Sbjct: 14 HGKERVRVARVWKNNQGHHFVVEWRVSISLLSDCLNSYLRDDNSDIVATDTMKNTVYAKA 73
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S+ ++E +AI LA+HF Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 74 KECSEILSVEDFAILLAKHFTSFYKQVTTAIVKIVEKPWERVNVDGQPHEHGFKL-GSEK 132
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LSLLK
Sbjct: 133 HTAEAIVQKSGALQLTSGIEGLSLLK 158
[16][TOP]
>UniRef100_A2SXR4 Uricase n=1 Tax=Nicotiana tabacum RepID=A2SXR4_TOBAC
Length = 307
Score = 132 bits (331), Expect = 2e-29
Identities = 68/147 (46%), Positives = 97/147 (65%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGKS+VR+ RVW+ DG +H EW+VN + SD A++ GDN+ + ATDT KNTVY
Sbjct: 13 HGKSRVRVARVWKSHDGK-YHFAEWSVNISLLSDCLPAYVAGDNSDIVATDTMKNTVYAK 71
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S++ + E +AI LA+HF Y V+ A + + +KPW R+ G H+HGF L G+E
Sbjct: 72 AKECSEQLSAEDFAIILAKHFTSFYQQVTAAIVDIVEKPWERISIKGQHHEHGFKL-GSE 130
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T V DK+GTL +T+G++ LS+LK
Sbjct: 131 KHTTEVMVDKSGTLRMTSGIEGLSVLK 157
[17][TOP]
>UniRef100_Q9SXZ9 Uricase n=1 Tax=Medicago sativa RepID=Q9SXZ9_MEDSA
Length = 308
Score = 131 bits (330), Expect = 3e-29
Identities = 65/147 (44%), Positives = 94/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW+ DG H +VEW V+ + SD ++++ DN+ + ATDT KNTVY
Sbjct: 14 HGKERVRVARVWKSKDGKQHFVVEWRVSINLLSDCVNSYIRDDNSDIVATDTMKNTVYAK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S+ ++E +AI LA+HF Y V+ A + + +KPW RV G PHDHGF L G+E
Sbjct: 74 AKECSEILSVEDFAILLAKHFTSFYSQVTTAIVKIVEKPWERVNVDGQPHDHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LS+LK
Sbjct: 133 RHTTEAIVKKSGALQLTSGIEGLSVLK 159
[18][TOP]
>UniRef100_Q9SXZ8 Uricase n=1 Tax=Medicago sativa RepID=Q9SXZ8_MEDSA
Length = 308
Score = 131 bits (330), Expect = 3e-29
Identities = 65/147 (44%), Positives = 94/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW+ DG H +VEW V+ + SD ++++ DN+ + ATDT KNTVY
Sbjct: 14 HGKERVRVARVWKSKDGKQHFVVEWRVSINLLSDCVNSYVRDDNSDIVATDTMKNTVYAK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S+ ++E +AI LA+HF Y V+ A + + +KPW RV G PHDHGF L G+E
Sbjct: 74 AKECSEILSVEDFAILLAKHFTSFYSQVTTAIVKIVEKPWERVNVDGQPHDHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LS+LK
Sbjct: 133 KHTTEAIVKKSGALQLTSGIEGLSVLK 159
[19][TOP]
>UniRef100_Q9LD80 Uricase n=1 Tax=Cicer arietinum RepID=Q9LD80_CICAR
Length = 308
Score = 129 bits (324), Expect = 1e-28
Identities = 65/147 (44%), Positives = 93/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW+ DG H +VEW V+ + SD ++++ DN+ + ATDT KNTVY
Sbjct: 14 HGKERVRVARVWKSKDGKRHFVVEWRVSINLLSDCVNSYIRDDNSDIVATDTMKNTVYAK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S+ + E +AI LA+HF Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 74 AKECSEILSAEDFAILLAKHFTSFYRQVTTAIVNIVEKPWERVSVDGQPHEHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LSLLK
Sbjct: 133 KHTTEAIVKKSGALQLTSGIEGLSLLK 159
[20][TOP]
>UniRef100_A2SXR2 Uricase n=1 Tax=Medicago truncatula RepID=A2SXR2_MEDTR
Length = 308
Score = 128 bits (322), Expect = 2e-28
Identities = 64/147 (43%), Positives = 93/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW+ DG +VEW V+ + SD ++++ DN+ + ATDT KNTVY
Sbjct: 14 HGKERVRVARVWKSKDGKQQFVVEWRVSINLLSDCVNSYVRDDNSDIVATDTMKNTVYAK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S+ ++E +AI LA+HF Y V+ A + + +KPW RV G PHDHGF L G+E
Sbjct: 74 AKECSEILSVEDFAILLAKHFTSFYSQVTTAIVKIVEKPWERVNVDGQPHDHGFKL-GSE 132
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LS+LK
Sbjct: 133 KHTTEAIVKKSGALQLTSGIEGLSVLK 159
[21][TOP]
>UniRef100_B9RSB9 Uricase n=1 Tax=Ricinus communis RepID=B9RSB9_RICCO
Length = 374
Score = 127 bits (319), Expect = 5e-28
Identities = 70/147 (47%), Positives = 94/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVWR DGN H MVEW+V+ + SD +A+ DN+ + ATDT KNTVYV
Sbjct: 14 HGKDRVRVTRVWRRNDGN-HFMVEWSVSISLLSDCLNAYSRDDNSNIVATDTMKNTVYVK 72
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ +++ + E +AI LAQHF Y V+ A I + +KPW RV H HGF L G+E
Sbjct: 73 AKECTEQLSAENFAILLAQHFTSFYKEVTTAIIKIVEKPWERVSIDDQLHTHGFKL-GSE 131
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T VT K+G L +T+G+ LS+LK
Sbjct: 132 KHTAEVTLTKSGDLQLTSGIVGLSVLK 158
[22][TOP]
>UniRef100_A2SXS0 Uricase n=1 Tax=Hordeum vulgare subsp. vulgare RepID=A2SXS0_HORVD
Length = 307
Score = 127 bits (318), Expect = 6e-28
Identities = 63/148 (42%), Positives = 95/148 (64%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR + H VEW+V + SD ++ + DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAEAGGHLFVEWSVAVSVVSDCLPSYTSDDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF L G+
Sbjct: 71 KAKECTEVVSMEEFAVILGRHFTSLYPQVSEATVTIVERPWERVAVDGKPHSHGFKL-GS 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E T VT K+G+L + +G++ SLLK
Sbjct: 130 EKHTTEVTVKKSGSLLINSGIQGYSLLK 157
[23][TOP]
>UniRef100_P53763 Uricase-2 n=1 Tax=Phaseolus vulgaris RepID=URIC_PHAVU
Length = 308
Score = 127 bits (318), Expect = 6e-28
Identities = 65/146 (44%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHH-MVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK +VR+ RVWR H +VEW V + SD +++L DN+ + ATDT KNTVY A
Sbjct: 15 HGKERVRVARVWRTPQGRHFVVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S ++E +AI LA+HFV Y V+ A + + +KPW RV G PH HGF L G+E
Sbjct: 75 KECSDILSVEDFAILLAKHFVSFYKKVTGAIVNIVEKPWERVIVDGQPHQHGFTL-GSEK 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G+L +T+G++ LS+LK
Sbjct: 134 HTTEAIVQKSGSLQLTSGIEGLSVLK 159
[24][TOP]
>UniRef100_C6TNK1 Uricase n=1 Tax=Glycine max RepID=C6TNK1_SOYBN
Length = 309
Score = 126 bits (317), Expect = 8e-28
Identities = 66/147 (44%), Positives = 93/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVW--RDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW R G H +VEW V + SD +++L DN+ + ATDT KNTVY
Sbjct: 16 HGKERVRVARVWKTRQGQ-HFIVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAK 74
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S + E++AI LA+HFV Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 AKECSDILSAEEFAILLAKHFVSFYQKVTGAIVNIVEKPWERVTVDGQPHEHGFKL-GSE 133
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G+L +T+G++ LS+LK
Sbjct: 134 KHTTEAIVQKSGSLQLTSGIEGLSVLK 160
[25][TOP]
>UniRef100_O04420 Uricase n=1 Tax=Arabidopsis thaliana RepID=URIC_ARATH
Length = 309
Score = 126 bits (317), Expect = 8e-28
Identities = 66/148 (44%), Positives = 95/148 (64%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGK++VR+GRVWR DG+ HH VEWNV+ + S ++ DN+ + ATDT KNTVYV
Sbjct: 14 HGKARVRVGRVWRHAHDGS-HHFVEWNVSISLLSHCLSSYRLDDNSDIVATDTIKNTVYV 72
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ + ++E++AI + +HF YP V A + + +KPW RV G PH HGF L G+
Sbjct: 73 KAKECGDRLSVEEFAILIGKHFCSFYPQVFTAIVNIIEKPWERVSIDGKPHLHGFKL-GS 131
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E T +K+G L++T+G+ L+LLK
Sbjct: 132 ENHTTEARVEKSGALNLTSGIGGLALLK 159
[26][TOP]
>UniRef100_P04670 Uricase-2 isozyme 1 n=1 Tax=Glycine max RepID=URIC1_SOYBN
Length = 309
Score = 126 bits (317), Expect = 8e-28
Identities = 66/147 (44%), Positives = 93/147 (63%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVW--RDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW R G H +VEW V + SD +++L DN+ + ATDT KNTVY
Sbjct: 16 HGKERVRVARVWKTRQGQ-HFIVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAK 74
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S + E++AI LA+HFV Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 AKECSDILSAEEFAILLAKHFVSFYQKVTGAIVNIVEKPWERVTVDGQPHEHGFKL-GSE 133
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G+L +T+G++ LS+LK
Sbjct: 134 KHTTEAIVQKSGSLQLTSGIEGLSVLK 160
[27][TOP]
>UniRef100_C6T8P1 Uricase n=1 Tax=Glycine max RepID=C6T8P1_SOYBN
Length = 243
Score = 125 bits (313), Expect = 2e-27
Identities = 66/147 (44%), Positives = 92/147 (62%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVW--RDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW R G H +VEW V + SD +++L DN+ + ATDT KNTVY
Sbjct: 16 HGKERVRVARVWKTRQGQ-HFVVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAK 74
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S + E +AI LA+HFV Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 AKECSDILSAEDFAILLAKHFVSFYKKVTGAIVNIVEKPWERVIVDGQPHEHGFKL-GSE 133
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G+L +T+G++ LS+LK
Sbjct: 134 KHTTEAIVQKSGSLQLTSGIEGLSVLK 160
[28][TOP]
>UniRef100_O04104 Uricase-2 isozyme 2 n=1 Tax=Glycine max RepID=URIC2_SOYBN
Length = 309
Score = 125 bits (313), Expect = 2e-27
Identities = 66/147 (44%), Positives = 92/147 (62%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVW--RDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW R G H +VEW V + SD +++L DN+ + ATDT KNTVY
Sbjct: 16 HGKERVRVARVWKTRQGQ-HFVVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAK 74
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S + E +AI LA+HFV Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 AKECSDILSAEDFAILLAKHFVSFYKKVTGAIVNIVEKPWERVIVDGQPHEHGFKL-GSE 133
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G+L +T+G++ LS+LK
Sbjct: 134 KHTTEAIVQKSGSLQLTSGIEGLSVLK 160
[29][TOP]
>UniRef100_A2SXR8 Uricase n=1 Tax=Sorghum bicolor RepID=A2SXR8_SORBI
Length = 306
Score = 124 bits (311), Expect = 4e-27
Identities = 62/148 (41%), Positives = 94/148 (63%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD---GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR H +VEWNV I SD ++++ DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGHIIVEWNVAVSIVSDCLPSYISSDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF + G
Sbjct: 71 KAKECTEVVSMEEFAVILGRHFTSLYPQVSEATVTIVERPWDRVTVDGKPHSHGFKV-GV 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E + V K+G+L + +G++ SLLK
Sbjct: 130 EKHSTEVIVKKSGSLLINSGIQGYSLLK 157
[30][TOP]
>UniRef100_A2SXR7 Uricase n=1 Tax=Saccharum officinarum RepID=A2SXR7_SACOF
Length = 306
Score = 124 bits (311), Expect = 4e-27
Identities = 62/148 (41%), Positives = 94/148 (63%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD---GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR H +VEWNV I SD ++++ DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGHVIVEWNVAVSIVSDCLPSYISSDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF + G
Sbjct: 71 KAKECTEVVSMEEFAVILGRHFTSLYPQVSEATVTIVERPWERVTVDGKPHSHGFKV-GV 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E + V K+G+L + +G++ SLLK
Sbjct: 130 EKHSTEVIVKKSGSLLINSGIQGYSLLK 157
[31][TOP]
>UniRef100_P34799 Uricase-2 isozyme 2 n=1 Tax=Canavalia lineata RepID=URIC2_CANLI
Length = 301
Score = 124 bits (311), Expect = 4e-27
Identities = 62/146 (42%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV-HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK +VR+ RVW+ + +VEW V + SD ++++ DN+ + ATDT KNTVY A
Sbjct: 15 HGKERVRVARVWKTKKGGYFIVEWRVGISLLSDCVNSYVRDDNSDIVATDTMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S+ ++E +AI LA+HF+ Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 KECSEILSVEDFAILLAKHFISFYKQVTAAIVNIVEKPWERVSVDGQPHEHGFKL-GSER 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LSLLK
Sbjct: 134 HTAEAIVQKSGALQLTSGIEGLSLLK 159
[32][TOP]
>UniRef100_P34798 Uricase-2 isozyme 1 n=1 Tax=Canavalia lineata RepID=URIC1_CANLI
Length = 308
Score = 123 bits (308), Expect = 9e-27
Identities = 61/146 (41%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV-HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
HGK +V++ RVW+ + +VEW V + SD ++++ DN+ + ATDT KNTVY A
Sbjct: 15 HGKERVQVARVWKTKQGWYFIVEWRVGNSLLSDCVNSYVRDDNSDIVATDTMKNTVYAKA 74
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ S+ ++E +AI LA+HF+ Y V+ A + + +KPW RV G PH+HGF L G+E
Sbjct: 75 KECSEILSVEDFAILLAKHFISFYKQVTAAIVNIVEKPWERVSVDGQPHEHGFKL-GSER 133
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
T K+G L +T+G++ LSLLK
Sbjct: 134 HTAEAIVQKSGALQLTSGIEGLSLLK 159
[33][TOP]
>UniRef100_Q5N7F6 Uricase n=1 Tax=Oryza sativa Japonica Group RepID=Q5N7F6_ORYSJ
Length = 186
Score = 122 bits (306), Expect = 2e-26
Identities = 62/148 (41%), Positives = 91/148 (61%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD---GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR H +VEWNV + SD ++ + DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGHVIVEWNVAVSVVSDCLPSYTSDDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF L G
Sbjct: 71 KAKECTEIVSMEEFAVILGRHFTSLYPQVSEATVTIAERPWERVVVDGKPHSHGFKL-GV 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E V K+G L + +G++ SLLK
Sbjct: 130 EKHVTEVIVKKSGNLLINSGIQGYSLLK 157
[34][TOP]
>UniRef100_Q94CU3 Uricase n=2 Tax=Oryza sativa RepID=Q94CU3_ORYSJ
Length = 307
Score = 122 bits (306), Expect = 2e-26
Identities = 62/148 (41%), Positives = 91/148 (61%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD---GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR H +VEWNV + SD ++ + DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGHVIVEWNVAVSVVSDCLPSYTSDDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF L G
Sbjct: 71 KAKECTEIVSMEEFAVILGRHFTSLYPQVSEATVTIAERPWERVVVDGKPHSHGFKL-GV 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E V K+G L + +G++ SLLK
Sbjct: 130 EKHVTEVIVKKSGNLLINSGIQGYSLLK 157
[35][TOP]
>UniRef100_B4G1P7 Uricase n=1 Tax=Zea mays RepID=B4G1P7_MAIZE
Length = 270
Score = 122 bits (305), Expect = 2e-26
Identities = 63/150 (42%), Positives = 95/150 (63%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWR-----DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
HGKS+VR+ RVWR G+V +VEWNV I SD ++ + DN+ + ATD+ KNTV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGDV--IVEWNVAVSIVSDCLPSYTSSDNSAIVATDSIKNTV 68
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
YV A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF +
Sbjct: 69 YVKAKECTEVVSMEEFAVILGRHFTSLYPQVSEATVTIVERPWERVTVDGKPHSHGFKV- 127
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G E + V K+G+L + +G++ SLLK
Sbjct: 128 GVEKHSTEVIVKKSGSLRINSGIQGYSLLK 157
[36][TOP]
>UniRef100_B4FTA4 Uricase n=1 Tax=Zea mays RepID=B4FTA4_MAIZE
Length = 307
Score = 122 bits (305), Expect = 2e-26
Identities = 63/150 (42%), Positives = 95/150 (63%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWR-----DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
HGKS+VR+ RVWR G+V +VEWNV I SD ++ + DN+ + ATD+ KNTV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGDV--IVEWNVAVSIVSDCLPSYTSSDNSAIVATDSIKNTV 68
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
YV A+ ++ ++E++A+ L +HF YP VS+A + + ++PW RV G PH HGF +
Sbjct: 69 YVKAKECTEVVSMEEFAVILGRHFTSLYPQVSEATVTIVERPWERVTVDGKPHSHGFKV- 127
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G E + V K+G+L + +G++ SLLK
Sbjct: 128 GVEKHSTEVIVKKSGSLRINSGIQGYSLLK 157
[37][TOP]
>UniRef100_A2SXR9 Uricase n=1 Tax=Triticum aestivum RepID=A2SXR9_WHEAT
Length = 307
Score = 122 bits (305), Expect = 2e-26
Identities = 61/148 (41%), Positives = 93/148 (62%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
HGKS+VR+ RVWR + H VEW+V + SD ++ + DN+ + ATD+ KNTVYV
Sbjct: 11 HGKSRVRVSRVWRRPAEAGGHLFVEWSVAVSVVSDCLPSYTSDDNSAIVATDSIKNTVYV 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ ++ ++E++A+ L +HF Y VS+A + + ++PW RV G PH HGF L G+
Sbjct: 71 KAKECTEVVSMEEFAVILGRHFTSLYSQVSEATVTIVERPWERVAVDGKPHSHGFKL-GS 129
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E T V K+G+L + +G++ SLLK
Sbjct: 130 EKHTTEVNVKKSGSLLINSGIQGYSLLK 157
[38][TOP]
>UniRef100_C4EN30 Uricase n=1 Tax=Streptosporangium roseum DSM 43021
RepID=C4EN30_STRRS
Length = 293
Score = 119 bits (298), Expect = 1e-25
Identities = 62/147 (42%), Positives = 92/147 (62%), Gaps = 1/147 (0%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ RV RDG VHH+ + NV++ + DM+ A L+GDNT + TDTQKNT Y
Sbjct: 8 NRYGKAETRVVRVVRDGGVHHIKDVNVSSALSGDMDEAHLSGDNTAILPTDTQKNTAYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHD-HGFALQGT 441
A++ IE +A+ LA+H+V + P V A++ +E+ W R+ G + H F G
Sbjct: 68 ARKYGVD-QIEDFALLLARHYVSSQPAVHHARVEIEEYFWDRIPVQGPSGERHSFVRSGR 126
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLL 522
EVRT V +D+ GT V +GLKDL +L
Sbjct: 127 EVRTCVVHHDRDGTTTVLSGLKDLVVL 153
[39][TOP]
>UniRef100_B6TFL8 Uricase n=1 Tax=Zea mays RepID=B6TFL8_MAIZE
Length = 306
Score = 118 bits (295), Expect = 3e-25
Identities = 61/150 (40%), Positives = 94/150 (62%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWR-----DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
HGKS+VR+ RVWR G+V +VEWN I SD ++ + DN+ + ATD+ KNTV
Sbjct: 11 HGKSRVRVSRVWRRPAAAGGDV--IVEWNXAVSIVSDCLPSYTSSDNSAIVATDSIKNTV 68
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
YV A+ ++ ++E++A+ L +HF YP V++A + + ++PW RV G PH HGF +
Sbjct: 69 YVKAKECTEVVSMEEFAVILGRHFTSLYPQVTEATVTIVERPWERVTVDGKPHSHGFKV- 127
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G E + V K+G+L + +G++ SLLK
Sbjct: 128 GVEKHSTEVIVKKSGSLLINSGIQGYSLLK 157
[40][TOP]
>UniRef100_A6W9R7 Uricase n=1 Tax=Kineococcus radiotolerans SRS30216
RepID=A6W9R7_KINRD
Length = 299
Score = 115 bits (288), Expect = 2e-24
Identities = 67/150 (44%), Positives = 87/150 (58%), Gaps = 3/150 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
H +GK++ R+ R RD H +V+ NV T + D A+L+GD + + TDTQKNTVY
Sbjct: 8 HRYGKAENRVVRFRRDTARHEIVDLNVTTTLRGDFADAYLSGDQSKVLPTDTQKNTVYAY 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ T+E YA+ LA+HFV VS A++ VE PWTR Q G HDH + G E
Sbjct: 68 AKEKGV-ATVEGYALDLARHFVDDVEPVSGARVDVEAYPWTRAQVGGNEHDHTWIRSGAE 126
Query: 445 VRTVYVTY---DKAGTLDVTAGLKDLSLLK 525
VRT T D + V AGLKDL+LLK
Sbjct: 127 VRTAAATVSDGDGRQVVHVLAGLKDLTLLK 156
[41][TOP]
>UniRef100_Q2JBQ6 Uricase n=1 Tax=Frankia sp. CcI3 RepID=Q2JBQ6_FRASC
Length = 297
Score = 114 bits (286), Expect = 3e-24
Identities = 64/147 (43%), Positives = 86/147 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VRL V R+G VH + + NV+T + D A L+GDN + TD QKNTVY
Sbjct: 8 NQYGKAEVRLVHVARNGPVHQITDLNVSTALRGDFAAAHLSGDNAHVLTTDAQKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ IE +AI L HF + P + A+I +EQ W R+Q G+PHDH F+ E
Sbjct: 68 AREHGIG-QIEDFAIRLGHHFAGSLPGIDGARIEIEQYRWDRIQVDGVPHDHAFSRSAGE 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT VT D+ GT V +GL L LLK
Sbjct: 127 KRTTVVTLDR-GTAFVVSGLAGLVLLK 152
[42][TOP]
>UniRef100_UPI0000E4847A PREDICTED: similar to MGC68684 protein, partial n=1
Tax=Strongylocentrotus purpuratus RepID=UPI0000E4847A
Length = 294
Score = 114 bits (284), Expect = 5e-24
Identities = 57/146 (39%), Positives = 91/146 (62%)
Frame = +1
Query: 88 HHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
++GKS V+L R+ +GNVHH+ E+ VN + + F +GDN+ + ATDTQKNTVY +A
Sbjct: 10 YYGKSAVKLLRLRAEGNVHHIKEFEVNVHLSLSSKKDFESGDNSDIIATDTQKNTVYALA 69
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ + K + EQ+ AL +HF+ ++ V ++++E+ PW R+ Q G H H F ++
Sbjct: 70 KLVGVK-SPEQFGQALCRHFLSSFRHVIAVRVHIEEAPWKRITQGGQEHVHAFVIEKQCT 128
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
R + ++ G + V AGLKDL +LK
Sbjct: 129 RFCDLLQERGGLVQVWAGLKDLKVLK 154
[43][TOP]
>UniRef100_Q0RH83 Uricase n=1 Tax=Frankia alni ACN14a RepID=Q0RH83_FRAAA
Length = 294
Score = 111 bits (278), Expect = 3e-23
Identities = 61/144 (42%), Positives = 83/144 (57%)
Frame = +1
Query: 94 GKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQR 273
GK+++RL V R G HH+ + NV+T + D A L GDN+ + TD QKNTVY A+
Sbjct: 8 GKAEIRLVHVDRTGPAHHLTDLNVSTALRGDFAAAHLTGDNSHVLTTDAQKNTVYAFARE 67
Query: 274 MSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVRT 453
IE +AI L +HFV ++P + A+I +EQ W R+ G+PHDH F+ G E RT
Sbjct: 68 HGIG-QIEDFAIRLGRHFVDSFPWIDGARIEIEQYHWNRIPVGGVPHDHAFSRAGGERRT 126
Query: 454 VYVTYDKAGTLDVTAGLKDLSLLK 525
VT D V +GL L +LK
Sbjct: 127 TVVTVDGDAAF-VVSGLAGLVVLK 149
[44][TOP]
>UniRef100_UPI0001B57FE4 urate oxidase n=1 Tax=Streptomyces sp. AA4 RepID=UPI0001B57FE4
Length = 296
Score = 110 bits (276), Expect = 5e-23
Identities = 60/147 (40%), Positives = 88/147 (59%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VRL V R G VHH+ + V++ + D+ L GDN+ + ATDTQKNTVY
Sbjct: 8 NQYGKAEVRLVTVRRTGGVHHLRDLTVSSALRGDLSATHLTGDNSAVLATDTQKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ IE +A+ L QHFV T ++ A+I +E++ W R+ G PHDH F+ G E
Sbjct: 68 AKQQDVG-EIEDFALRLGQHFVGTQEKITGARISIEEQEWDRITVDGAPHDHSFSRSGGE 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT VT A V +G+ L++LK
Sbjct: 127 RRTTTVTV-HADRAWVVSGVDGLTVLK 152
[45][TOP]
>UniRef100_B7FHK5 Uricase n=1 Tax=Medicago truncatula RepID=B7FHK5_MEDTR
Length = 236
Score = 110 bits (276), Expect = 5e-23
Identities = 56/127 (44%), Positives = 81/127 (63%), Gaps = 2/127 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
HGK +VR+ RVW+ DG +VEW V+ + SD ++++ DN+ + ATDT KNTVY
Sbjct: 14 HGKERVRVARVWKSKDGKQQFVVEWRVSINLLSDCVNSYVRDDNSDIVATDTMKNTVYAK 73
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S+ ++E +AI LA+HF Y V+ A + + +KPW RV G PHDHGF L G+E
Sbjct: 74 AKECSEILSVEDFAILLAKHFTSFYSQVTTAIVKIVEKPWERVNVDGQPHDHGFKL-GSE 132
Query: 445 VRTVYVT 465
+ +Y T
Sbjct: 133 -KPLYFT 138
[46][TOP]
>UniRef100_C8XJZ7 Urate oxidase n=1 Tax=Nakamurella multipartita DSM 44233
RepID=C8XJZ7_9ACTO
Length = 302
Score = 109 bits (273), Expect = 1e-22
Identities = 59/148 (39%), Positives = 85/148 (57%), Gaps = 1/148 (0%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ RV+RD + H +V++NV+ + D E GDN+ TD KNTV
Sbjct: 8 NQYGKAETRVVRVYRDSDPHEIVDYNVSVALSGDFEEIHRTGDNSNCLTTDATKNTVNAF 67
Query: 265 AQRMSQKCTI-EQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ S+ E + IALA+HFV V++A+I +E PW R+ G PH H FA G
Sbjct: 68 AKEYSEAARQPESFGIALAKHFVDDTAPVTRARIKLEMYPWNRLSHDGTPHPHAFARDGG 127
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT VTYD L V +G++D +LK
Sbjct: 128 YVRTATVTYD-GTNLWVVSGVQDYVVLK 154
[47][TOP]
>UniRef100_UPI0001B4CED1 uricase n=1 Tax=Streptomyces hygroscopicus ATCC 53653
RepID=UPI0001B4CED1
Length = 293
Score = 105 bits (262), Expect = 2e-21
Identities = 56/146 (38%), Positives = 85/146 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R+ RDG+VHH+ + NV+ + DM +GDNTG+ TDT KNTVY
Sbjct: 7 NQYGKAETRVVRMVRDGDVHHIKDLNVSVALSGDMADVHRHGDNTGVLPTDTMKNTVYAF 66
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ T E + I LA+HFV + + A++ +E+ W R++ G H F G E
Sbjct: 67 AKEHG-IATAEHFGIELARHFVGSQETIRTARVRIEEYAWERIETGGETR-HSFVRAGQE 124
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
RT V YD +V +GLKDL+++
Sbjct: 125 TRTAQVRYD-GRDWEVLSGLKDLTVM 149
[48][TOP]
>UniRef100_C9ZGK9 Putative uricase n=1 Tax=Streptomyces scabiei 87.22
RepID=C9ZGK9_STRSC
Length = 301
Score = 105 bits (262), Expect = 2e-21
Identities = 54/146 (36%), Positives = 87/146 (59%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG HH+ + NV+ + DM L+G N + TDT KNTVY
Sbjct: 8 NQYGKAENRVVKITRDGATHHIKDLNVSVSLSGDMTEVHLSGSNANVLPTDTTKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + + EQ+ I LA+HFV + P + +A+I VE+ W R++ G H F +G E
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVTSQPAIHRARIRVEEYAWERIEHGG-EGAHSFVRRGQE 125
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
R +TYD + +V +GLKDL+++
Sbjct: 126 TRLAQITYD-GSSWEVVSGLKDLTVM 150
[49][TOP]
>UniRef100_C1YNE1 Uricase n=1 Tax=Nocardiopsis dassonvillei subsp. dassonvillei DSM
43111 RepID=C1YNE1_NOCDA
Length = 303
Score = 105 bits (261), Expect = 3e-21
Identities = 59/148 (39%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VRL V RD +VH + + NV + + ++E GDN+ TDTQKNTVY
Sbjct: 13 NQYGKAEVRLVHVNRDTDVHRIKDVNVTSQLRGELETVHTLGDNSTCLPTDTQKNTVYAK 72
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ +E +A+ LA+HFV + V A+ V + W R+Q S PHDH F+ +G E
Sbjct: 73 AREWGGVGAVEDFALRLARHFVDEHEYVHGARQEVHEYSWERIQTSSGPHDHAFSRKGAE 132
Query: 445 VRTVYVTYDKAGTLD-VTAGLKDLSLLK 525
RT VT K G + V +G + LS+LK
Sbjct: 133 TRTTVVT--KTGDREWVVSGFEGLSVLK 158
[50][TOP]
>UniRef100_B1MCN6 Uricase n=1 Tax=Mycobacterium abscessus ATCC 19977
RepID=B1MCN6_MYCA9
Length = 302
Score = 104 bits (259), Expect = 4e-21
Identities = 58/150 (38%), Positives = 86/150 (57%), Gaps = 3/150 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R++RD H + + NV + + D A+ +GD + TD+QK T+Y
Sbjct: 8 NQYGKAENRVVRIYRDTPRHEIKDLNVGSALRGDFAAAYTDGDQRKVLPTDSQKQTIYAY 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + TIEQY + LA+HFV Y V+ A+I +++ W RV G HDH + +G E
Sbjct: 68 AKEKGIE-TIEQYGLELARHFVDDYEPVTGARIEIDEYAWERVTVDGREHDHTWVRKGQE 126
Query: 445 VRTVYVTYDKAGTLD---VTAGLKDLSLLK 525
VRT VT D G V GLKDL +LK
Sbjct: 127 VRTAEVTVDGVGAQQQTWVIGGLKDLVVLK 156
[51][TOP]
>UniRef100_A1RA35 Uricase n=1 Tax=Arthrobacter aurescens TC1 RepID=A1RA35_ARTAT
Length = 304
Score = 103 bits (258), Expect = 6e-21
Identities = 59/147 (40%), Positives = 84/147 (57%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ +V RD + HH+ + NV + + D + A L GDN + ATDTQKNTVY
Sbjct: 12 NQYGKAEVRVVKVTRDTDRHHIEDLNVTSQLRGDFQAAHLEGDNGHVVATDTQKNTVYAF 71
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + E + + LA HF + V+ + E W R+Q G HDH F G E
Sbjct: 72 AREGIG--SPESFLLRLADHFTGGFDWVTGGRWEAEAYSWDRIQAHGEGHDHSFVRNGQE 129
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT V D A T + +GLKDL++LK
Sbjct: 130 VRTAVVVRDGA-TTHLISGLKDLTVLK 155
[52][TOP]
>UniRef100_A0QRZ8 Uricase n=1 Tax=Mycobacterium smegmatis str. MC2 155
RepID=A0QRZ8_MYCS2
Length = 299
Score = 103 bits (258), Expect = 6e-21
Identities = 59/155 (38%), Positives = 88/155 (56%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M+ L + +GK++ R+ R++RD H + + NV+T + D A L GD + + TD+
Sbjct: 1 MSDIILGKNQYGKAENRVVRIYRDSPRHEIRDLNVSTCLRGDFSGAHLTGDQSQVLPTDS 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QK T Y A++ TIE+Y +ALA+HFV V+ A+I +++ W RV G HDH
Sbjct: 61 QKQTAYAYAKQPGIT-TIEEYGLALARHFVDDVEPVAAARIEIDEYAWERVVVDGTEHDH 119
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+ +G E RT VT D G + GLKDL +LK
Sbjct: 120 TWIRKGQETRTAAVTVDADGAW-IVGGLKDLVILK 153
[53][TOP]
>UniRef100_Q6C2B4 Uricase n=1 Tax=Yarrowia lipolytica RepID=Q6C2B4_YARLI
Length = 311
Score = 103 bits (258), Expect = 6e-21
Identities = 55/156 (35%), Positives = 89/156 (57%), Gaps = 11/156 (7%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK VR+ +V RD + + + E V +++ D+E ++ DNT + ATDT KNT ++
Sbjct: 8 YGKDNVRVLKVSRDPSNPKIQQVQELVVKCLLEGDIEVSYTKADNTPIVATDTVKNTTFI 67
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
VA+++ IE + LA HF++ YP +S A + +EQ WT+ +G H F GT
Sbjct: 68 VAKQLPGTWPIELFGAVLADHFIKKYPHISSAHVDIEQYKWTKYDVNGKTSQHSFVHDGT 127
Query: 442 EVRTVYV--------TYDKAGTLDVTAGLKDLSLLK 525
E+RTV+V + T ++ +G+KDLS+LK
Sbjct: 128 ELRTVHVDRYRDAAKNPETVTTFNIASGIKDLSVLK 163
[54][TOP]
>UniRef100_B8HFX6 Uricase n=1 Tax=Arthrobacter chlorophenolicus A6 RepID=B8HFX6_ARTCA
Length = 302
Score = 103 bits (256), Expect = 1e-20
Identities = 56/147 (38%), Positives = 83/147 (56%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ ++ RD N H + + NV + + D A L GDN + ATDTQKNT+Y
Sbjct: 10 NQYGKAEVRVVKITRDTNRHEIEDLNVTSQLRGDFSAAHLEGDNAHVVATDTQKNTIYAF 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + E + + L +HF ++ VS + E W R+Q G HDH F G E
Sbjct: 70 AR--DGIGSPEAFLLRLGEHFTSSFDWVSGGRWEAESYAWNRIQAHGSEHDHSFVRNGQE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT + D A T + +GLKDL++LK
Sbjct: 128 VRTAVLVRDGA-TSHLISGLKDLTVLK 153
[55][TOP]
>UniRef100_C3JGB2 Uricase n=1 Tax=Rhodococcus erythropolis SK121 RepID=C3JGB2_RHOER
Length = 320
Score = 103 bits (256), Expect = 1e-20
Identities = 61/166 (36%), Positives = 91/166 (54%)
Frame = +1
Query: 28 LPTRASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLN 207
+ T ++N+ + L H +GK++ R+ R++RD H + + NV+T + D A+L
Sbjct: 11 ITTGSTNTERLSGSIELSGHQYGKAENRVVRIYRDTPRHEIHDINVSTCLRGDFADAYLT 70
Query: 208 GDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWT 387
GD + + TDTQK T Y A+ +IE Y + LA+HFV VS A+I +E+ W
Sbjct: 71 GDQSKVLPTDTQKQTAYSYAKEKG-LISIETYGLELARHFVDDIEPVSGARIEIEEYAWE 129
Query: 388 RVQQSGLPHDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R G HD+ + +G EVRT +T GT V GLKDL +LK
Sbjct: 130 RAIVDGSEHDYTWIRKGQEVRTASITISDTGTW-VIGGLKDLVILK 174
[56][TOP]
>UniRef100_B5HRQ5 Uricase n=1 Tax=Streptomyces sviceus ATCC 29083 RepID=B5HRQ5_9ACTO
Length = 297
Score = 103 bits (256), Expect = 1e-20
Identities = 55/146 (37%), Positives = 85/146 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GKS+ R+ ++ RDG HH+ + NV+ + DME +G N + TDT KNTVY
Sbjct: 7 NQYGKSENRVVKITRDGATHHIKDLNVSVALSGDMEEVHYSGSNANVLPTDTTKNTVYAF 66
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + + EQ+ I LA+HFV + + A+I VE+ W R++ G H F QG E
Sbjct: 67 AKEHGIESS-EQFGIHLARHFVTSQEPIRTARIRVEEYSWERIETPG-EDAHSFVRQGQE 124
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
R +TYD + +V +GLKDL+++
Sbjct: 125 TRLTQITYD-GSSWEVVSGLKDLTVM 149
[57][TOP]
>UniRef100_C0ZWT7 Uricase n=1 Tax=Rhodococcus erythropolis PR4 RepID=C0ZWT7_RHOE4
Length = 325
Score = 102 bits (255), Expect = 1e-20
Identities = 59/151 (39%), Positives = 84/151 (55%), Gaps = 4/151 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
H +GK++ R+ R++RD H + + NV+T + D A+L GD + + TDTQK T Y
Sbjct: 30 HQYGKAENRVVRIYRDTPRHEIHDINVSTCLRGDFADAYLTGDQSKVLPTDTQKQTAYSY 89
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ +IE Y + LA+HFV VS A+I +E+ W R G HD+ + +G E
Sbjct: 90 AKEKGL-ISIETYGLELARHFVDDIEPVSGARIEIEEYAWERAIVDGSEHDYTWIRKGQE 148
Query: 445 VRTVYVTYDKAGTLD----VTAGLKDLSLLK 525
VRT +T GT D V GLKDL +LK
Sbjct: 149 VRTASITVSDTGTADAGTWVIGGLKDLVILK 179
[58][TOP]
>UniRef100_B5GK38 Uricase n=1 Tax=Streptomyces sp. SPB74 RepID=B5GK38_9ACTO
Length = 296
Score = 102 bits (254), Expect = 2e-20
Identities = 57/146 (39%), Positives = 87/146 (59%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ RV R+G VHH+ + NV+ + D++ L G NT TDT KNTVYV
Sbjct: 5 NQYGKAEVRVVRVVREGAVHHLRDLNVSIALSGDLDDVHLTGANTHCLPTDTMKNTVYVF 64
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + E++A+ LA+HF T P + +A++ VE+ W R+ H FA +G E
Sbjct: 65 AKEHG-IASPEEFALRLARHFATTRPGIHRARVRVEEYAWDRLTDPADGPAHSFARRGGE 123
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
R VT++ AG V +GLK L++L
Sbjct: 124 TRLAEVTHE-AGRQQVISGLKGLTVL 148
[59][TOP]
>UniRef100_Q0S841 Uricase n=1 Tax=Rhodococcus jostii RHA1 RepID=Q0S841_RHOSR
Length = 303
Score = 101 bits (252), Expect = 3e-20
Identities = 57/147 (38%), Positives = 83/147 (56%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
H +GK++ R+ R++RD H + + +V+T + D A L GD + + TDTQK T +
Sbjct: 13 HQYGKAENRIVRIYRDTPRHEIRDVSVSTCLRGDFSAAHLAGDQSSVLPTDTQKQTAFSY 72
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ +IE+Y + LA+HFV V A+I +E+ W R G HDH + +G E
Sbjct: 73 AKEKGLD-SIEEYGLTLARHFVDDVAPVEGARIEIEEYAWQRAVVDGAEHDHTWVRKGEE 131
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT +T D GT V GLKDL +LK
Sbjct: 132 VRTAAITVDGDGTW-VVGGLKDLVILK 157
[60][TOP]
>UniRef100_C1BAH3 Uricase n=1 Tax=Rhodococcus opacus B4 RepID=C1BAH3_RHOOB
Length = 303
Score = 101 bits (251), Expect = 4e-20
Identities = 57/147 (38%), Positives = 84/147 (57%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R++RD H + + +V+T + D A L GD + + TDTQK T Y
Sbjct: 13 NQYGKAENRIVRIYRDTPRHEIRDVSVSTCLRGDFSAAHLAGDQSSVLPTDTQKQTAYSY 72
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ +IE+Y + LA+HFV V+ A+I +E+ W R G HDH + +G E
Sbjct: 73 AKEKGLD-SIEEYGLTLARHFVDDVAPVAGARIEIEEYAWQRAVVDGAEHDHTWVRKGEE 131
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT +T D GT V GLKDL +LK
Sbjct: 132 VRTAAITVDADGTW-VVGGLKDLVILK 157
[61][TOP]
>UniRef100_UPI000155C3B5 PREDICTED: hypothetical protein n=1 Tax=Ornithorhynchus anatinus
RepID=UPI000155C3B5
Length = 310
Score = 100 bits (250), Expect = 5e-20
Identities = 51/145 (35%), Positives = 87/145 (60%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ ++ RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 27 YGKDMVKVLQIQRDGKYHTIKEVAASVQLTLSSKKDYLHGDNSDIIPTDTIKNTVHVLAK 86
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K TIE +A+ + +HF+ ++ VS+A++Y+E+ PW R +++G H H F T +
Sbjct: 87 FKGIK-TIETFAMDICEHFLSSFSHVSRARVYIEEAPWQRFEKNGARHVHAFIHSPTGIH 145
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G DV +G+KD+ LLK
Sbjct: 146 FCEVEQFRNGNPDVHSGIKDMKLLK 170
[62][TOP]
>UniRef100_UPI0001B506B8 uricase n=1 Tax=Streptomyces viridochromogenes DSM 40736
RepID=UPI0001B506B8
Length = 298
Score = 100 bits (249), Expect = 6e-20
Identities = 54/146 (36%), Positives = 86/146 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG HH+ + NV+ + DM+ +G N + TDT KNTVY
Sbjct: 8 NQYGKAENRVVKITRDGATHHIKDLNVSVSLSGDMDEVHYSGSNANVLPTDTTKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + + EQ+ I LA+HFV + + A+I VE+ W R+ SG +H F +G E
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVTSQEPIRTARIRVEEYAWDRIAVSG-EAEHSFVRKGQE 125
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
VR +TYD + +V +GLKDL ++
Sbjct: 126 VRLTQITYD-GTSWEVVSGLKDLVVM 150
[63][TOP]
>UniRef100_A4FPC7 Uricase n=1 Tax=Saccharopolyspora erythraea NRRL 2338
RepID=A4FPC7_SACEN
Length = 296
Score = 100 bits (249), Expect = 6e-20
Identities = 57/147 (38%), Positives = 84/147 (57%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ V +D H + + NV+T + D++ L GDN+ TDTQKNTVY
Sbjct: 8 NQYGKAEVRIVSVNKDTPRHTIKDLNVSTSLRGDLDAVHLTGDNSNCLPTDTQKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + IE +A+ L +HFV T ++ A+I +++ W R+ G HDH FA E
Sbjct: 68 AKE-APIGEIEDFALRLGRHFVNTAEGITGARILIDEYSWERIPVGGTGHDHSFARSTDE 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT VT D V +GLKDL +LK
Sbjct: 127 KRTTAVTID-GDKAHVVSGLKDLVVLK 152
[64][TOP]
>UniRef100_C6WEX2 Uricase n=1 Tax=Actinosynnema mirum DSM 43827 RepID=C6WEX2_ACTMD
Length = 293
Score = 100 bits (249), Expect = 6e-20
Identities = 57/147 (38%), Positives = 86/147 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VRL V RDG+ H + + V+T + D+ L GDNT + ATDTQKNT Y
Sbjct: 8 NQYGKAEVRLVSVTRDGDTHSIKDLTVSTSLRGDLVDTHLTGDNTKVLATDTQKNTAYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A ++ +E +A+ LA+HFV ++ A++ V++ W R++ +G H F G E
Sbjct: 68 A-KLYGVHQVEDFALRLARHFVAGQAAITGARVLVDEHLWQRIETNG----HSFTRSGGE 122
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+RT VT D V +GLKDL +LK
Sbjct: 123 IRTAAVTVDHDRAW-VVSGLKDLVVLK 148
[65][TOP]
>UniRef100_UPI0001B56F26 uricase n=1 Tax=Streptomyces sp. SPB78 RepID=UPI0001B56F26
Length = 318
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/153 (36%), Positives = 85/153 (55%)
Frame = +1
Query: 64 ATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQ 243
A L + +GK++VR+ RV R+G VHH+ + NV+ + ++ L G N TDT
Sbjct: 20 AVSVLGQNQYGKAEVRVVRVVREGAVHHLRDLNVSIALSGALDDVHLTGSNANCLPTDTM 79
Query: 244 KNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHG 423
KNTVYV A+ + E++A LA+HFV T P + +A++ VE+ W R+ H
Sbjct: 80 KNTVYVFAKEHG-IASPEEFATRLARHFVTTQPSIHRARVRVEEYAWDRLTDPAAGPAHS 138
Query: 424 FALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
FA +G E R + Y+ G V +GLK L++L
Sbjct: 139 FARRGGETRLAEIAYED-GHWQVISGLKGLTVL 170
[66][TOP]
>UniRef100_UPI0001AEF806 uricase n=1 Tax=Streptomyces ghanaensis ATCC 14672
RepID=UPI0001AEF806
Length = 321
Score = 99.8 bits (247), Expect = 1e-19
Identities = 56/154 (36%), Positives = 87/154 (56%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R+ RDG HH+ + NV+ + DME +G N + TDT KNTVY
Sbjct: 19 NQYGKAETRVVRITRDGATHHIKDLNVSVALSGDMEEVHYSGSNAHVLPTDTTKNTVYAF 78
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGL-----PHD---H 420
A+ + + E++ I LA+HFV + + +A+I +E+ W R+ SG P D H
Sbjct: 79 AKEYGVE-SAERFGIDLARHFVTSQEPIHRARIRIEEYAWERIGTSGADGTGHPADGTGH 137
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
F +G E R VTYD +V +GLKDL+++
Sbjct: 138 SFVRKGQETRLAQVTYD-GEDWEVVSGLKDLTVM 170
[67][TOP]
>UniRef100_A8NVS5 Uricase n=1 Tax=Coprinopsis cinerea okayama7#130 RepID=A8NVS5_COPC7
Length = 367
Score = 99.8 bits (247), Expect = 1e-19
Identities = 57/164 (34%), Positives = 89/164 (54%), Gaps = 6/164 (3%)
Frame = +1
Query: 52 TTNMATYA-LPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMT 228
T+N A + L +GK+ VR+ R+ R+G HH VE+NV T+++ D+E ++ DN+ +
Sbjct: 2 TSNAAELSYLSYARYGKTSVRVFRIVREGKWHHTVEYNVETLLEGDIETSYTEADNSVVV 61
Query: 229 ATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGL 408
ATD+ KN Y +A+ E++A+ + FV Y + KA + VEQ W R+ +G
Sbjct: 62 ATDSVKNITYYLAKVSPHILNAEKFALHIGTFFVSKYAHIHKAHVTVEQLRWKRISINGE 121
Query: 409 PHDHGFALQGTEVRTVYVTYD-----KAGTLDVTAGLKDLSLLK 525
H H F G + R V D A +V++GL DL +LK
Sbjct: 122 EHPHSFYRDGDDKRVVKAVVDATAGKHALVANVSSGLVDLLVLK 165
[68][TOP]
>UniRef100_Q1AS73 Uricase n=1 Tax=Rubrobacter xylanophilus DSM 9941
RepID=Q1AS73_RUBXD
Length = 294
Score = 99.4 bits (246), Expect = 1e-19
Identities = 52/146 (35%), Positives = 82/146 (56%)
Frame = +1
Query: 88 HHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
++GKS +RL +V+R+ H + E V+ + D A + GDNTG+ ATDT +NTVY +A
Sbjct: 19 NYGKSDIRLVKVFRNPGRHEIKELRVDVSQEGDFAAAHVEGDNTGLMATDTMRNTVYALA 78
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
R + E + + L +HF+ P ++ ++ + + W R++ G PH+H F E
Sbjct: 79 -RDRLTGSAEAFGVELVRHFLEAAPRANRVRVSMVEHLWERIEAGGKPHEHSFVRAAGE- 136
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT V D+ G V AG+ DL +LK
Sbjct: 137 RTAEVVGDEEGNFSVEAGIDDLLVLK 162
[69][TOP]
>UniRef100_A0K0I2 Uricase n=1 Tax=Arthrobacter sp. FB24 RepID=A0K0I2_ARTS2
Length = 302
Score = 99.4 bits (246), Expect = 1e-19
Identities = 53/147 (36%), Positives = 83/147 (56%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ ++ RD + H + + NV + + D A L GDN+ + ATDTQKNT+Y
Sbjct: 10 NQYGKAEVRVVKITRDTDRHEIEDLNVTSQLRGDFAAAHLQGDNSHVVATDTQKNTIYAF 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + E + + L +HF ++ V+ + E W R+Q G HDH F G E
Sbjct: 70 AR--EGVGSPEAFLLRLGEHFTSSFDWVTGGRWEAESYSWDRIQAHGAEHDHSFVRNGQE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT + D A + +GLKDL++LK
Sbjct: 128 VRTAVLVRDGAAA-HLISGLKDLTVLK 153
[70][TOP]
>UniRef100_UPI0001B5253B uricase n=1 Tax=Streptomyces griseoflavus Tu4000
RepID=UPI0001B5253B
Length = 301
Score = 98.6 bits (244), Expect = 2e-19
Identities = 52/146 (35%), Positives = 85/146 (58%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R+ RDG HH+ + NV+ + DME +G N + TDT KNTVY
Sbjct: 8 NQYGKAENRVVRITRDGATHHIKDLNVSVALSGDMEEVHYSGSNASVLPTDTTKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + + EQ+ I LA+HFV + + +A+I +E+ W R+ G +H F +G E
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVTSQEPIRRARIRIEEYGWERIGTPG-EGEHSFVRKGQE 125
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
R +T+D +V +GLKDL+++
Sbjct: 126 TRLAQITFD-GEEWEVVSGLKDLTVM 150
[71][TOP]
>UniRef100_UPI0000F2BA8E PREDICTED: similar to urate oxidase (EC 1.7.3.3) - baboon n=1
Tax=Monodelphis domestica RepID=UPI0000F2BA8E
Length = 354
Score = 98.6 bits (244), Expect = 2e-19
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK VR+ + RDGN H + E + + + +L GDN+ + TDT KNTV+V+A+
Sbjct: 71 YGKDMVRVLHIQRDGNYHTIKEVAASVQLTLSTKKDYLYGDNSDIIPTDTIKNTVHVLAK 130
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ TIE +A+ + +HF+ ++ V++AK+Y+E+ PW R++++G+ H H F T
Sbjct: 131 FKGIR-TIETFAMDICEHFLSSFNHVNRAKVYIEEAPWKRLEKNGVEHVHAFINTPTGTH 189
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G V AG+KD+ +LK
Sbjct: 190 FCEVEQYRNGPPTVHAGIKDMKVLK 214
[72][TOP]
>UniRef100_UPI0000E80A8A PREDICTED: similar to urate oxidase (EC 1.7.3.3) n=1 Tax=Gallus
gallus RepID=UPI0000E80A8A
Length = 320
Score = 98.6 bits (244), Expect = 2e-19
Identities = 53/145 (36%), Positives = 85/145 (58%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ ++ R+ R+G H + E V T + H +L+G+N+ + TDT KN V V+A+
Sbjct: 28 YGKNTIKFLRLHREGKKHFVKEVEVCTHLRLTSAHEYLDGNNSFVIPTDTIKNIVLVLAK 87
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ +IEQ+AI + +HF+ T+ V+ K Y+++ PW R Q+G+PH H F L +R
Sbjct: 88 KNGIS-SIEQFAIDICKHFMTTFCQVAYVKTYIQEVPWQRQYQNGVPHIHSFILVPDGIR 146
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ G L V AG+KDL L+K
Sbjct: 147 FCEAEQCRNGPLVVCAGIKDLKLMK 171
[73][TOP]
>UniRef100_UPI0000ECB3CD UPI0000ECB3CD related cluster n=1 Tax=Gallus gallus
RepID=UPI0000ECB3CD
Length = 281
Score = 98.6 bits (244), Expect = 2e-19
Identities = 53/145 (36%), Positives = 85/145 (58%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ ++ R+ R+G H + E V T + H +L+G+N+ + TDT KN V V+A+
Sbjct: 1 YGKNTIKFLRLHREGKKHFVKEVEVCTHLRLTSAHEYLDGNNSFVIPTDTIKNIVLVLAK 60
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ +IEQ+AI + +HF+ T+ V+ K Y+++ PW R Q+G+PH H F L +R
Sbjct: 61 KNGIS-SIEQFAIDICKHFMTTFCQVAYVKTYIQEVPWQRQYQNGVPHIHSFILVPDGIR 119
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ G L V AG+KDL L+K
Sbjct: 120 FCEAEQCRNGPLVVCAGIKDLKLMK 144
[74][TOP]
>UniRef100_UPI0001B580EA urate oxidase n=1 Tax=Streptomyces sp. AA4 RepID=UPI0001B580EA
Length = 290
Score = 98.2 bits (243), Expect = 3e-19
Identities = 56/146 (38%), Positives = 82/146 (56%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ RL RV RDG+ H + + V+ + DM L G N + ATDTQKNTV+
Sbjct: 8 NRYGKAENRLVRVDRDGDEHRITDLTVSVSLSGDMSDTHLTGANDKVLATDTQKNTVFAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + IE +A+ LA+HFV + + A++ + PW R+Q G P H FA G
Sbjct: 68 ARDGIGE--IEDFALRLARHFVSSQESIHLARVGIVAHPWERLQVGGRPAHHSFARSGAG 125
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
RT VTYD V G++DL++L
Sbjct: 126 TRTTRVTYDGERAW-VLGGVEDLTVL 150
[75][TOP]
>UniRef100_C0U015 Uricase n=1 Tax=Geodermatophilus obscurus DSM 43160
RepID=C0U015_9ACTO
Length = 292
Score = 97.8 bits (242), Expect = 4e-19
Identities = 56/152 (36%), Positives = 86/152 (56%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
+ L + +GK++ R+ RV+RD + H +V+++V+ + + L GDN+ + TDTQKN
Sbjct: 3 FVLGHNQYGKAENRVVRVFRDSDPHEIVDYDVSVALWGGQDAPHLTGDNSPVLPTDTQKN 62
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFA 429
TVY A+ E + I LA+HFV ++ A++ +E PWTR L + H F
Sbjct: 63 TVYAFAKEDDVVAQPESFGIRLARHFVDDTEPITHARVRIEMYPWTR-----LGNPHAFT 117
Query: 430 LQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G VRT VTYD T V +G++DL +LK
Sbjct: 118 RDGRFVRTATVTYD-GSTTWVVSGVEDLWILK 148
[76][TOP]
>UniRef100_B5HFQ6 Uricase n=1 Tax=Streptomyces pristinaespiralis ATCC 25486
RepID=B5HFQ6_STRPR
Length = 310
Score = 97.4 bits (241), Expect = 5e-19
Identities = 53/154 (34%), Positives = 88/154 (57%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG+ HH+ + NV+ + DM+ +G N + TDT KNTVY
Sbjct: 8 NQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDTTKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS-------GLPH-DH 420
A+ + + EQ+ I LA+HFV + + +A+I +E+ W R++ S G H
Sbjct: 68 AKEYGIE-SAEQFGIHLARHFVTSQEPIHRARIRIEEYAWERIETSDGNSRFIGADEVKH 126
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
F +G E RT +TYD +V +GLKDL+++
Sbjct: 127 SFVRKGQETRTTQITYD-GEQWEVVSGLKDLTVM 159
[77][TOP]
>UniRef100_Q5YNZ7 Uricase n=1 Tax=Nocardia farcinica RepID=Q5YNZ7_NOCFA
Length = 297
Score = 96.3 bits (238), Expect = 1e-18
Identities = 54/147 (36%), Positives = 82/147 (55%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GKS+ R+ R+ RDG H + + V+T + D A++ GD + + TD+QK T Y
Sbjct: 12 NRYGKSENRIVRIHRDGPRHEIRDVTVSTRLRGDFADAYVTGDQSAVLPTDSQKQTAYAY 71
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ IE Y +ALA+HFVR V A++ +++ W R + HDH + +G E
Sbjct: 72 AKTQGLH-HIEDYGLALAEHFVRDIAPVHAARVEIDEFAWERARVGPGEHDHTWVRRGPE 130
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VRT VT G+ V G++DL LLK
Sbjct: 131 VRTAAVTVTGTGSW-VVGGVRDLVLLK 156
[78][TOP]
>UniRef100_UPI0001866D86 hypothetical protein BRAFLDRAFT_229846 n=1 Tax=Branchiostoma
floridae RepID=UPI0001866D86
Length = 295
Score = 95.9 bits (237), Expect = 2e-18
Identities = 55/146 (37%), Positives = 83/146 (56%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMV-EWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
+GK+ VRL + R G H + E V+T + + +L+GDN+ + ATDTQKNTVY +A
Sbjct: 11 YGKNWVRLLHIRRLGGKHQDIRELEVSTSLTLSSKKDYLHGDNSDIIATDTQKNTVYALA 70
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ T EQ+ + L HF+ ++ V++ K+ V PW R++ G H H F + V
Sbjct: 71 KTKGVT-TPEQFGLDLCHHFLSSFSHVTRVKVDVTMAPWRRMKIDGKDHAHAFIMTPDAV 129
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
R +V + GT V AGLKD+ +LK
Sbjct: 130 RFCHVEQARQGTPVVHAGLKDMKILK 155
[79][TOP]
>UniRef100_B5GRN0 Uricase n=1 Tax=Streptomyces clavuligerus ATCC 27064
RepID=B5GRN0_STRCL
Length = 301
Score = 95.5 bits (236), Expect = 2e-18
Identities = 55/156 (35%), Positives = 86/156 (55%), Gaps = 2/156 (1%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
MAT L + +GK++ R+ R+ RDG HH+ + +V+ + DM+ +G N + TDT
Sbjct: 1 MAT-TLGQNQYGKAESRVVRIVRDGPTHHIKDLSVSIALSGDMDDVHYSGSNAHVLPTDT 59
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP--H 414
KNTVY A R + E + I LA+HFV + V +A++ +E+ W R+ G P
Sbjct: 60 AKNTVYAFA-REHGIASAEHFGIRLARHFVTSQRTVHRARVRIEEYAWERIAAPGSPTGR 118
Query: 415 DHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
H F G E R +T+D G ++ +GLK L++L
Sbjct: 119 AHSFVRAGQETRVCQITFD-GGRWEIVSGLKGLTVL 153
[80][TOP]
>UniRef100_UPI0001AEEB77 uricase n=1 Tax=Streptomyces albus J1074 RepID=UPI0001AEEB77
Length = 323
Score = 95.1 bits (235), Expect = 3e-18
Identities = 56/176 (31%), Positives = 93/176 (52%), Gaps = 8/176 (4%)
Frame = +1
Query: 19 IKPLPTRASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHA 198
++P P R + S ++ L + +GK++ R+ ++ R+G HH+ + NV+ + DME
Sbjct: 3 VRPQPGRPAASRSSRPVM-LGQNQYGKAENRVVKITREGATHHIKDLNVSVALSGDMEEV 61
Query: 199 FLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQK 378
+G N + TDT KNTV+ A+ + + EQ+ I LA+HFV + + +A+I +E+
Sbjct: 62 HYSGSNANVLPTDTTKNTVFAFAKEHGIE-SAEQFGIHLARHFVTSQEPIHQARIRIEEY 120
Query: 379 PWTRVQQSGLPHD--------HGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
W R+ S H F QG E R +TYD +V +GLKDL ++
Sbjct: 121 AWERIPASDANSQFIGADEVKHSFVRQGQETRLTQITYD-GERWEVVSGLKDLVVM 175
[81][TOP]
>UniRef100_Q17J02 Uricase n=1 Tax=Aedes aegypti RepID=Q17J02_AEDAE
Length = 325
Score = 95.1 bits (235), Expect = 3e-18
Identities = 53/157 (33%), Positives = 90/157 (57%), Gaps = 5/157 (3%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + + +GK V++ V R+G VH + E+ V T + + +L GDN+ + ATD+QKN
Sbjct: 22 YKISNYGYGKDSVKVLHVMRNGLVHSIKEFEVGTKLKLASQKDYLQGDNSDIVATDSQKN 81
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP----HD 417
TVY++A++ K + E++ I L HF+ Y V++ I++++ PW+R+ P H+
Sbjct: 82 TVYLLARKHGLK-SPEEFGILLCDHFLNKYSHVNEVSIHIDEYPWSRMGFGKGPYQDLHN 140
Query: 418 HGFALQGTEVRTVYVTYDKAGTL-DVTAGLKDLSLLK 525
H F T +R VT + ++ V +GL DL +LK
Sbjct: 141 HAFVFTPTAIRYCDVTQKRGDSMPTVISGLSDLRVLK 177
[82][TOP]
>UniRef100_A9EQU4 Uricase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9EQU4_SORC5
Length = 281
Score = 94.7 bits (234), Expect = 3e-18
Identities = 50/145 (34%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GKS+VRL +V R G H + + V+ ++ + + A+ GDN+ + TDT KNTVY +A+
Sbjct: 10 YGKSRVRLVKVRRAGARHELTDVQVDVQLEGEFDDAYTKGDNSKVLPTDTMKNTVYALAK 69
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ IE + + LA+HF+ P +A++ + + W+RV G PH H F E R
Sbjct: 70 GHPVE-PIEDFGVLLAEHFLGK-PHTRRARVAIAENVWSRVDAGGAPHPHAFLRAAGERR 127
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
T ++ G +++T+G+ DL +LK
Sbjct: 128 TAEISAAPGG-VEITSGIADLLVLK 151
[83][TOP]
>UniRef100_Q82LJ2 Uricase n=1 Tax=Streptomyces avermitilis RepID=Q82LJ2_STRAW
Length = 315
Score = 94.4 bits (233), Expect = 4e-18
Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG HH+ + NV+ + DM+ +G N + TDT KNTVY
Sbjct: 16 NQYGKAENRVVKITRDGATHHIKDLNVSVALSGDMDEVHYSGSNANVLPTDTTKNTVYAF 75
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPH--------DH 420
A+ + + EQ+ I LA+HFV + + A+I +E+ W R++ S H
Sbjct: 76 AKEHGIE-SAEQFGIHLARHFVTSQEPIKTARIRIEEYTWERIEASDANSRFIGADEVKH 134
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
F +G E R +TYD + +V +GLKDL ++
Sbjct: 135 SFVRKGQETRVTQITYD-GSSWEVISGLKDLVVM 167
[84][TOP]
>UniRef100_Q9HGI9 Uricase n=1 Tax=Isaria tenuipes RepID=Q9HGI9_PAETN
Length = 302
Score = 94.4 bits (233), Expect = 4e-18
Identities = 51/147 (34%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VRL + RD N VH + E V +++ D+E ++ DN+ + ATD+ KNTV+V+
Sbjct: 9 YGKDNVRLFKTHRDPNTGVHSVTETVVCVLLEGDIESSYTRADNSVVVATDSMKNTVFVL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A + HFV TYP + A + V W R++ G PH H F + E
Sbjct: 69 AKQ-HPVTPPELFAATVGAHFVDTYPHIHVAAVRVVTTRWARIRVDGRPHPHSFVKESEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RTV + + + +G+ DL++LK
Sbjct: 128 KRTVAARASRRAGIAINSGIADLTVLK 154
[85][TOP]
>UniRef100_C9NEY4 Urate oxidase n=1 Tax=Streptomyces flavogriseus ATCC 33331
RepID=C9NEY4_9ACTO
Length = 310
Score = 94.0 bits (232), Expect = 6e-18
Identities = 53/154 (34%), Positives = 86/154 (55%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ R+ RDG+ HH+ + NV+ + DM+ +G N + TDT KNTVY
Sbjct: 8 NQYGKAENRVVRITRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDTTKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS-------GLPH-DH 420
A+ + + EQ+ I LA+HFV + + A+I +E+ W R+ S G H
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVTSQEPIEVARIRIEEYAWERIATSDGNSKFIGADEVKH 126
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
F +G E RT +T+D +V +GLKDL+++
Sbjct: 127 SFVRKGQETRTTQITFD-GEKWEVISGLKDLTVM 159
[86][TOP]
>UniRef100_C7PZT3 Urate oxidase n=1 Tax=Catenulispora acidiphila DSM 44928
RepID=C7PZT3_CATAD
Length = 287
Score = 94.0 bits (232), Expect = 6e-18
Identities = 52/146 (35%), Positives = 81/146 (55%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK + R+ R+ + G VH + + V+ + D++ L GDN+G+ TDT KNT +
Sbjct: 8 NRYGKCENRIVRITKQGPVHQIKDITVSVALSGDLDATHLTGDNSGVLPTDTMKNTCFAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
AQR IE+YA+ LA+HFV + P + A++ V++ W R+ Q H F G
Sbjct: 68 AQRHG-AVEIEEYALLLARHFVDSQPSIGHARVEVDEHAWDRIGQG----PHSFVRTGGG 122
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
RT V YD V +G+KDL++L
Sbjct: 123 TRTCTVHYDGTAAW-VLSGVKDLTVL 147
[87][TOP]
>UniRef100_B1VVF4 Uricase n=1 Tax=Streptomyces griseus subsp. griseus NBRC 13350
RepID=B1VVF4_STRGG
Length = 307
Score = 93.6 bits (231), Expect = 8e-18
Identities = 50/154 (32%), Positives = 86/154 (55%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG+ HH+ + NV+ + DM+ +G N + TDT KNTV+
Sbjct: 8 NQYGKAENRVVKIVRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDTTKNTVFAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPH--------DH 420
A+ + + EQ+ I LA+HFV + + +A+I +E+ W R+ S H
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVSSQEPIHRARIRIEEYAWERIATSDANSKFIGADEVQH 126
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
FA +G E R +TYD ++ +GLKDL+++
Sbjct: 127 SFARKGMETRVSQITYD-GENWEIISGLKDLTVM 159
[88][TOP]
>UniRef100_C7PNR9 Urate oxidase n=1 Tax=Chitinophaga pinensis DSM 2588
RepID=C7PNR9_CHIPD
Length = 281
Score = 93.6 bits (231), Expect = 8e-18
Identities = 54/145 (37%), Positives = 80/145 (55%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V+L ++ R H + +VN + D E A GDN + TDTQKNTVY +A
Sbjct: 10 YGKNAVQLSKIIRRPAYHEFRQISVNVSLKGDFEEAHTLGDNAKILPTDTQKNTVYALA- 68
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
R K +IE +A+ L HFV T P VS+A + + + + R+ G H H + G E
Sbjct: 69 RDHFKTSIEDFALHLVHHFVTTQPQVSEATVEIAEHAYHRLLLDGAEHPHAYISGGQEKH 128
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
T V D A ++ V++G+ DL +LK
Sbjct: 129 TTLVRKD-AESISVSSGISDLLILK 152
[89][TOP]
>UniRef100_A5DFP1 Uricase n=1 Tax=Pichia guilliermondii RepID=A5DFP1_PICGU
Length = 301
Score = 93.6 bits (231), Expect = 8e-18
Identities = 50/148 (33%), Positives = 85/148 (57%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V ++ + +++ NV ++ + + ++ DN+ + TDT KNTV V
Sbjct: 8 YGKGNVKFLKVKKNPSNPKEQDILQANVQVLLRGNFDISYTKADNSPIVPTDTVKNTVLV 67
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A + + IE++A LA+HF+ Y VS +I ++Q WTR +G PH H F G
Sbjct: 68 EA-KTTDVWPIERFAAHLAKHFINKYSHVSGIEITIQQARWTRFDVNGKPHAHSFRHDGP 126
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E R Y+ YD++G L + + +KDL++LK
Sbjct: 127 ETRNTYLNYDRSGKLVLESSIKDLTVLK 154
[90][TOP]
>UniRef100_UPI0001AED1E2 putative uricase n=1 Tax=Streptomyces roseosporus NRRL 15998
RepID=UPI0001AED1E2
Length = 307
Score = 93.2 bits (230), Expect = 1e-17
Identities = 52/154 (33%), Positives = 88/154 (57%), Gaps = 8/154 (5%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++ R+ ++ RDG+ HH+ + NV+ + DM+ +G N + TDT KNTV+
Sbjct: 8 NQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDTTKNTVFAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSG-----LPHD---H 420
A+ + + EQ+ I LA+HFV + + +A+I +E+ W R+ S + D H
Sbjct: 68 AKEHGIE-SAEQFGIHLARHFVSSQEPIHRARIRIEEYAWERIATSDGNSRFIGADDVKH 126
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
FA +G E R +TYD +V +GLKDL+++
Sbjct: 127 SFARKGQETRVSQITYD-GENWEVISGLKDLTVM 159
[91][TOP]
>UniRef100_Q6P700 Uricase n=1 Tax=Xenopus laevis RepID=Q6P700_XENLA
Length = 304
Score = 93.2 bits (230), Expect = 1e-17
Identities = 44/145 (30%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ ++ R+G H + E + + + +L GDN + TDT KNT+Y + +
Sbjct: 21 YGKNAVKVLQIKRNGKQHFIKEIEASVQLTLKSKKDYLEGDNADIIPTDTIKNTIYALTK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K TIE++++ LA+HF+ ++ V+ K+++E+ PW R++++G+ H H F V
Sbjct: 81 LKGIK-TIEEFSMELARHFLTSFNHVTDVKVFIEEAPWRRIEKNGMSHVHAFIYSPEGVH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ K G + +G+K+L +LK
Sbjct: 140 FCELQQQKGGQPAIYSGIKELRILK 164
[92][TOP]
>UniRef100_B4V2A8 Uricase n=1 Tax=Streptomyces sp. Mg1 RepID=B4V2A8_9ACTO
Length = 307
Score = 93.2 bits (230), Expect = 1e-17
Identities = 55/162 (33%), Positives = 88/162 (54%), Gaps = 8/162 (4%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
MAT L + +GK++ R+ ++ RDG+ HH+ + NV+ + DM+ +G N + TDT
Sbjct: 1 MATI-LGQNQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDT 59
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPH-- 414
KNTVY A+ + + EQ+ I LA+ FV + + +A+I +E+ W R+ S
Sbjct: 60 TKNTVYAFAKEHGIE-SAEQFGIHLARWFVNSQEPIQRARIRIEEYAWDRIATSDANSKF 118
Query: 415 ------DHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
+H F QG E R +TYD +V +GLKDL ++
Sbjct: 119 IGSDEVNHSFVRQGMETRVTQITYD-GTNWEVISGLKDLVVM 159
[93][TOP]
>UniRef100_C3YTP0 Uricase n=1 Tax=Branchiostoma floridae RepID=C3YTP0_BRAFL
Length = 295
Score = 93.2 bits (230), Expect = 1e-17
Identities = 52/146 (35%), Positives = 82/146 (56%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMV-EWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
+GK+ VRL + R G H + E V+T + + +L+GDN+ + ATDTQKNTVY +A
Sbjct: 11 YGKNWVRLLHIRRLGGKHQDIRELEVSTSLTLSSKKDYLHGDNSDIIATDTQKNTVYALA 70
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
+ T EQ+ + L HF+ ++ +++ K+ + PW R++ G H H F + V
Sbjct: 71 KTKGVT-TPEQFGLDLCHHFLSSFSHITRVKVDITMAPWRRMKIGGKDHAHAFIMTPDAV 129
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
R +V + G V AGLKD+ +LK
Sbjct: 130 RFCHVEQARQGAPVVHAGLKDMKILK 155
[94][TOP]
>UniRef100_C1GSE2 Uricase n=1 Tax=Paracoccidioides brasiliensis Pb01
RepID=C1GSE2_PARBA
Length = 307
Score = 93.2 bits (230), Expect = 1e-17
Identities = 50/147 (34%), Positives = 82/147 (55%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDG--NVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V+R+ VH +VE V +++ ++E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKDNVRVYKVYRNEVTGVHTVVEMTVCVLLEGEIESSYTQADNSVVVATDSMKNTIYIM 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A ++ E +A L HFV+TY + A + + WTR+ PH H F GTE
Sbjct: 70 A-KLHPVTPPELFASILGTHFVKTYKHIHTAHVDIITHRWTRMTIDDEPHQHSFLRDGTE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V T K + +T+ + LS+LK
Sbjct: 129 TRNVSATVTKRTGISLTSAIAGLSVLK 155
[95][TOP]
>UniRef100_Q6DG85 Uricase n=1 Tax=Danio rerio RepID=Q6DG85_DANRE
Length = 298
Score = 92.8 bits (229), Expect = 1e-17
Identities = 46/145 (31%), Positives = 85/145 (58%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R+GN HH++E N + +L GDN+ + TDT KNTV+ +A+
Sbjct: 16 YGKNMVKVLHIRREGNHHHIIELIANVQLTLKTRKDYLTGDNSDIIPTDTVKNTVHALAK 75
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ + V++ K+ +++ PW R++++G+ H+H F +R
Sbjct: 76 LKGIK-SIESFALDICEHFLTAFNHVTRVKVNIDEVPWKRLEKNGVEHNHAFIHCPEALR 134
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ T V +GLKD+ +LK
Sbjct: 135 FCEAEQYLSKTPVVHSGLKDMKVLK 159
[96][TOP]
>UniRef100_B0UMZ6 Uricase n=1 Tax=Methylobacterium sp. 4-46 RepID=B0UMZ6_METS4
Length = 279
Score = 92.8 bits (229), Expect = 1e-17
Identities = 50/145 (34%), Positives = 73/145 (50%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK +VR+ RV RDG H + E V M+ + AF DN+ +TDT KN V +VA
Sbjct: 8 YGKGRVRVMRVHRDGARHEVRELTVQAMLTGGFDPAFTRADNSTTVSTDTVKNVVNIVA- 66
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
R S E++ A+A+ + Y +V A + + W+R+ G PH H F L G
Sbjct: 67 RESMTLAPEEFCRAVARRLIDAYAMVETATVTAHETRWSRLAVDGEPHPHAFTLDGNGTS 126
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
VT + G L + +GL + LK
Sbjct: 127 VAKVTMARGGALTIESGLSGFTFLK 151
[97][TOP]
>UniRef100_B4V5M5 Uricase n=1 Tax=Streptomyces sp. Mg1 RepID=B4V5M5_9ACTO
Length = 305
Score = 92.8 bits (229), Expect = 1e-17
Identities = 52/157 (33%), Positives = 83/157 (52%), Gaps = 3/157 (1%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTA 231
M+ + L + +GK++ R+ +V R DG+ H + + NV+ + + L GDN
Sbjct: 1 MSKHVLAQNQYGKAENRIVKVTRKGGDGSWHEIRDLNVSVALRGEFRDVHLTGDNANCLP 60
Query: 232 TDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP 411
TDT KNTVY + E + I LA+HFV + + +A+I +E+ W R+
Sbjct: 61 TDTTKNTVYAFGKEHGIDSP-EAFGILLAKHFVSSQAPIREAQIRIEEYVWDRIPVPTRK 119
Query: 412 HDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
H F +G EVRT +TY + L V +GLKDL+++
Sbjct: 120 EQHSFVRKGQEVRTAQITYSETTGLQVISGLKDLTVM 156
[98][TOP]
>UniRef100_B0W8Y2 Uricase n=1 Tax=Culex quinquefasciatus RepID=B0W8Y2_CULQU
Length = 326
Score = 92.8 bits (229), Expect = 1e-17
Identities = 54/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ V R+G VH + E+ V T + + +L GDN+ + ATD+QKNTVY++A+
Sbjct: 30 YGKDSVKVMHVVRNGLVHSIKEFEVGTKLKLASQKDYLQGDNSDIVATDSQKNTVYLLAR 89
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP----HDHGFALQG 438
+ K + E++ I L HF+ Y V++ I++E+ PW+R+ P H+H F
Sbjct: 90 KHGLK-SPEEFGILLCNHFLTKYSHVNEVSIHIEEYPWSRMGFGKGPYQALHNHAFVFTP 148
Query: 439 TEVRTVYVTYDKA-GTLDVTAGLKDLSLLK 525
T R VT ++ T V +GL DL +LK
Sbjct: 149 TATRYCDVTQKRSESTPTVISGLTDLRVLK 178
[99][TOP]
>UniRef100_UPI0001B552E1 putative uricase n=1 Tax=Streptomyces sp. C RepID=UPI0001B552E1
Length = 307
Score = 92.4 bits (228), Expect = 2e-17
Identities = 54/162 (33%), Positives = 88/162 (54%), Gaps = 8/162 (4%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
MAT L + +GK++ R+ ++ RDG+ HH+ + NV+ + DM+ +G N + TDT
Sbjct: 1 MATI-LGQNQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMDDVHYSGSNANVLPTDT 59
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPH-- 414
KNTVY A+ + + EQ+ I LA+ FV + + +A+I +E+ W R+ S
Sbjct: 60 TKNTVYAFAKEYGIE-SAEQFGIHLARWFVNSQEPIQRARIRIEEYAWDRIATSDANSKF 118
Query: 415 ------DHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
+H F +G E R +TYD +V +GLKDL ++
Sbjct: 119 IGADEVNHSFVRKGMETRVTQITYD-GQNWEVVSGLKDLIVM 159
[100][TOP]
>UniRef100_A8L1E6 Uricase n=1 Tax=Frankia sp. EAN1pec RepID=A8L1E6_FRASN
Length = 301
Score = 92.4 bits (228), Expect = 2e-17
Identities = 54/147 (36%), Positives = 76/147 (51%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VRL V R H + + V+T + D A GDN+ + TDTQKN VY
Sbjct: 8 NQYGKAEVRLVHVDRSTPAHRITDLTVSTALRGDFTAAHTRGDNSHVLTTDTQKNVVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A R IEQ+A L +HF T ++ A+I +EQ W R+ G HDH F G
Sbjct: 68 A-REGGVGEIEQFASRLGRHFTTTADWITGARIEIEQHEWERITVDGREHDHSFVRSGRG 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT VT + A + +GL L +L+
Sbjct: 127 TRTTVVTVE-ADAVHAVSGLAGLVVLR 152
[101][TOP]
>UniRef100_Q8CJN8 Uricase n=1 Tax=Streptomyces coelicolor RepID=Q8CJN8_STRCO
Length = 311
Score = 92.0 bits (227), Expect = 2e-17
Identities = 52/162 (32%), Positives = 85/162 (52%), Gaps = 8/162 (4%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M + L + +GK++ R+ ++ RDG+ HH+ + NV+ + DME +G N + TDT
Sbjct: 1 MTRFVLGQNQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMEEVHRSGSNANVLPTDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS------ 402
KNTV+ A+ + + E + LA+HFV + +A+I +E+ W R++ S
Sbjct: 61 TKNTVFAFAKEHGIE-SAEDLGVKLARHFVDNNEPIHRARIRIEEFGWERIETSKGGARF 119
Query: 403 --GLPHDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
H F G E R +TYD G + V +G KDL++L
Sbjct: 120 VGAEEIAHSFVRTGQETRVAEITYDGHG-IQVLSGFKDLTVL 160
[102][TOP]
>UniRef100_Q3HWK9 Uricase n=1 Tax=Bombyx mori RepID=Q3HWK9_BOMMO
Length = 337
Score = 92.0 bits (227), Expect = 2e-17
Identities = 55/147 (37%), Positives = 81/147 (55%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
H +GKS V+L V RD H + E+ V T + E A++ GDN + ATD+QKNTVY++
Sbjct: 48 HGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLL 107
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ K T E++ + HF+ Y V +AK V + PW R+ Q+G PH H F
Sbjct: 108 AKKYGVK-TPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERL-QAGTPHSHAFVFSPIA 165
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+ + + V +GL L +LK
Sbjct: 166 TRWSEVSQTRHEAVVVKSGLSGLRVLK 192
[103][TOP]
>UniRef100_P16164 Uricase n=1 Tax=Sus scrofa RepID=URIC_PIG
Length = 304
Score = 92.0 bits (227), Expect = 2e-17
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK +++ + RDG H + E + + + +L+GDN+ + TDT KNTV V+A+
Sbjct: 21 YGKDMIKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYLHGDNSDVIPTDTIKNTVNVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V +A++YVE+ PW R +++G+ H H F T
Sbjct: 81 FKGIK-SIETFAVTICEHFLSSFKHVIRAQVYVEEVPWKRFEKNGVKHVHAFIYTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G + +G+KDL +LK
Sbjct: 140 FCEVEQIRNGPPVIHSGIKDLKVLK 164
[104][TOP]
>UniRef100_UPI00015B5245 PREDICTED: similar to uricase n=1 Tax=Nasonia vitripennis
RepID=UPI00015B5245
Length = 387
Score = 91.7 bits (226), Expect = 3e-17
Identities = 51/153 (33%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMV-EWNVNTMIDSDMEHAFLNGDNTGMTATDTQK 246
+ L + +GK+ V+L V R+ + H + E+ ++ + + +L GDN + ATD+QK
Sbjct: 90 FELGAYGYGKNNVKLLYVRRENALRHEIREYEIDVHLRLSTQKDYLVGDNRDIIATDSQK 149
Query: 247 NTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGF 426
NTVY++A++ K E++AI L HF+ Y V + + VE+ PW+R + +G+ H+H F
Sbjct: 150 NTVYLMAKKHGVKSP-EEFAIILCSHFLYQYRHVEEVNVRVEEYPWSRHEVNGVSHNHAF 208
Query: 427 ALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
T R VT + + + GLK+L +LK
Sbjct: 209 VFTPTATRYCQVTQLRNESPRIRGGLKNLRVLK 241
[105][TOP]
>UniRef100_Q0SGF5 Uricase n=1 Tax=Rhodococcus jostii RHA1 RepID=Q0SGF5_RHOSR
Length = 297
Score = 91.7 bits (226), Expect = 3e-17
Identities = 52/155 (33%), Positives = 81/155 (52%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M+ L + +GK++VRL ++ RD H + + V + + D++ GDN + ATDT
Sbjct: 1 MSKIVLGQNQYGKAEVRLVKITRDTKRHEIEDVTVTSQLRGDLDAVHTEGDNAHVVATDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTVY A+ +IE +A+ L QHF + ++ + +EQ W R+ G HDH
Sbjct: 61 QKNTVYAFAR--DGVGSIETFAMRLGQHFTGEFEWITGGRWEIEQYSWARIPVDGEGHDH 118
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
F E R VT D T + +GL ++ +LK
Sbjct: 119 SFVRSSDERRNTVVTMDGDRTW-IVSGLSNMVVLK 152
[106][TOP]
>UniRef100_C8XJY6 Urate oxidase n=1 Tax=Nakamurella multipartita DSM 44233
RepID=C8XJY6_9ACTO
Length = 297
Score = 91.7 bits (226), Expect = 3e-17
Identities = 56/147 (38%), Positives = 82/147 (55%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ V R VH + + NV + + D L G N + ATDTQKNTVY +
Sbjct: 8 NQYGKAEVRMVYVDRSTPVHAITDVNVTSQLIGDFTDTHLTGANDAVIATDTQKNTVYAM 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A R + E++A+ LA+++V Y V+ A++ VEQ W R+ + PHDH F+ E
Sbjct: 68 A-RTGGVGSPEEFALRLARNYVDKYEQVTGARMAVEQYSWDRIVTAAGPHDHAFSKGTAE 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT V D A V +GL L +LK
Sbjct: 127 TRTAVVRKDGAAE-TVISGLTGLVVLK 152
[107][TOP]
>UniRef100_Q2H717 Uricase n=1 Tax=Chaetomium globosum RepID=Q2H717_CHAGB
Length = 303
Score = 91.7 bits (226), Expect = 3e-17
Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD VH + E V +++ +E ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVCKVQRDEQTGVHTVTEMTVCCLLEGKIETSYTEADNSVVVATDSIKNTIYIK 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E YA L QHF+ TYP ++ A + V WTR+ G PH H F G E
Sbjct: 69 AKEHPVNPP-EVYASHLGQHFLDTYPHITVAHVDVVVHRWTRMAIDGAPHPHSFFRDGQE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V T + +D+ + + LS+LK
Sbjct: 128 TRNVKATVARGAGIDLNSSIAGLSVLK 154
[108][TOP]
>UniRef100_C0S2N5 Uricase n=2 Tax=Paracoccidioides brasiliensis RepID=C0S2N5_PARBP
Length = 307
Score = 91.7 bits (226), Expect = 3e-17
Identities = 49/147 (33%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDG--NVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V+R+ H +VE V +++ ++E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKDNVRVYKVYRNEVTGAHTVVEMTVCVLLEGEIESSYTQADNSVVVATDSMKNTIYIM 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A ++ E +A L HFV+TY + A + + WTR+ PH H F GTE
Sbjct: 70 A-KLHPVTPPELFASILGTHFVKTYKHIHTAHVDIITHRWTRMTIDDEPHQHSFLRDGTE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V T K + +T+ + LS+LK
Sbjct: 129 TRNVSATVTKGTGITLTSAIAGLSVLK 155
[109][TOP]
>UniRef100_A5DUZ6 Uricase n=1 Tax=Lodderomyces elongisporus RepID=A5DUZ6_LODEL
Length = 303
Score = 91.7 bits (226), Expect = 3e-17
Identities = 50/149 (33%), Positives = 81/149 (54%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK+ V+ +V +D N V ++E NV ++ + ++ DN+ + TDT KNT+ V
Sbjct: 10 YGKANVKFLKVRKDANNPKVQEILEANVKVLLRGKFDTSYTEADNSSIVPTDTVKNTILV 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A + IE +A LA+HF Y V ++ + Q W ++Q G HDH F +G
Sbjct: 70 EA-KTHNVWPIESFAAHLAKHFTSKYEQVEGIEVSIVQALWKKIQLEGKEHDHSFKHEGP 128
Query: 442 EVRTVYVTYDKAG-TLDVTAGLKDLSLLK 525
E R Y+ Y+KA L +++ +KDL +LK
Sbjct: 129 ETRQTYLNYEKASKKLQLSSSIKDLKVLK 157
[110][TOP]
>UniRef100_B9XKX5 Uricase n=1 Tax=bacterium Ellin514 RepID=B9XKX5_9BACT
Length = 279
Score = 91.3 bits (225), Expect = 4e-17
Identities = 48/145 (33%), Positives = 86/145 (59%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK +VR+ +V R+G+ H + E +V+ ++ D ++ +GDN+ + TDT KNTV +A+
Sbjct: 8 YGKDRVRVMKVTRNGSEHTVKEVDVSVALEGDFVSSYTSGDNSTVVPTDTMKNTVNALAK 67
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ T E++ IAL +HF++ Y + K +++ ++ W R+ G PH H F+
Sbjct: 68 QHLGGET-ERFGIALGEHFLKHYSQIQKVTLHLSERMWKRLSIDGKPHPHAFSGNSEACP 126
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+VT ++ L V +G+KDL +LK
Sbjct: 127 FAHVTCNRDKIL-VESGIKDLLILK 150
[111][TOP]
>UniRef100_C6HHE7 Uricase n=1 Tax=Ajellomyces capsulatus H143 RepID=C6HHE7_AJECH
Length = 300
Score = 91.3 bits (225), Expect = 4e-17
Identities = 54/166 (32%), Positives = 84/166 (50%), Gaps = 13/166 (7%)
Frame = +1
Query: 67 TYALPLHHHGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
T L +GK VR+ +V R + VH +VE V +++ D+E ++ DN+ + ATD+
Sbjct: 2 TPKLAAARYGKDNVRVYKVHRNEETGVHTVVETTVCVLLEGDIETSYTKADNSVVVATDS 61
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
KNT+Y++A ++ E +A L HF TYP + A + + WTR+ G PH H
Sbjct: 62 MKNTIYIMA-KLHPVTPPELFASILGSHFTTTYPHIHTAHVDIVTLRWTRMTFDGKPHPH 120
Query: 421 GFALQGTEVRTVYVTYDKA-----------GTLDVTAGLKDLSLLK 525
F GTE R V T + T+ +T+ + LS+LK
Sbjct: 121 SFLRDGTETRNVSATVSEGNSGSKDITSLPSTISLTSSISGLSVLK 166
[112][TOP]
>UniRef100_Q8MKJ2 Uricase n=1 Tax=Aotus trivirgatus RepID=URIC_AOTTR
Length = 304
Score = 91.3 bits (225), Expect = 4e-17
Identities = 47/145 (32%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+ +A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYLHGDNSDIIPTDTIKNTVHALAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + QHF+ ++ V + ++YVE+ PW R++++G+ H H F T
Sbjct: 81 FKGIK-SIEAFAVNICQHFLSSFNHVIRTQVYVEEIPWKRLEKNGVKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 140 FCEVEQLRSGPPVIHSGIKDLKVLK 164
[113][TOP]
>UniRef100_UPI0001B7BD1B UPI0001B7BD1B related cluster n=1 Tax=Rattus norvegicus
RepID=UPI0001B7BD1B
Length = 302
Score = 90.9 bits (224), Expect = 5e-17
Identities = 48/145 (33%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 20 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAK 79
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V++A +YVE+ PW R +++G+ H H F T
Sbjct: 80 FKGIK-SIETFAMNICEHFLSSFSHVTRAHVYVEEVPWKRFEKNGVKHVHAFIHTPTGTH 138
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G + +G+KDL +LK
Sbjct: 139 FCDVEQVRNGPPIIHSGIKDLKVLK 163
[114][TOP]
>UniRef100_C5FBX5 Uricase n=1 Tax=Microsporum canis CBS 113480 RepID=C5FBX5_NANOT
Length = 306
Score = 90.9 bits (224), Expect = 5e-17
Identities = 49/147 (33%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD--GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD +VE V TM++ D++ ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKENVRVYKVHRDEAAGTQTVVEMTVCTMLEGDIDVSYTKADNSVVVATDSIKNTIYIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E +A + HFV+ Y + A ++V + W+R+ +G PH H F +E
Sbjct: 70 AKQ-NPVTPPELFASIVGDHFVQKYKHIHVAHVHVVAQRWSRMNINGKPHPHSFLKDASE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VR+ VT + +D+ L LS+LK
Sbjct: 129 VRSADVTVTEGKGIDIKTSLSGLSVLK 155
[115][TOP]
>UniRef100_P09118 Uricase n=1 Tax=Rattus norvegicus RepID=URIC_RAT
Length = 303
Score = 90.9 bits (224), Expect = 5e-17
Identities = 48/145 (33%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V++A +YVE+ PW R +++G+ H H F T
Sbjct: 81 FKGIK-SIETFAMNICEHFLSSFSHVTRAHVYVEEVPWKRFEKNGVKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G + +G+KDL +LK
Sbjct: 140 FCDVEQVRNGPPIIHSGIKDLKVLK 164
[116][TOP]
>UniRef100_UPI000155E28A PREDICTED: similar to urate oxidase n=1 Tax=Equus caballus
RepID=UPI000155E28A
Length = 312
Score = 90.5 bits (223), Expect = 6e-17
Identities = 47/145 (32%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK ++L + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 29 YGKDMIKLLHIQRDGKYHSIKEVAASVQLTLSSKKEYLHGDNSDIIPTDTIKNTVHVLAK 88
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+++ +HF+ ++ V +A++Y+E+ W R +++G+ H H F T
Sbjct: 89 FKGIK-SIEAFAMSICEHFLSSFNHVIRAQVYMEEVSWKRFEKNGVKHVHAFIHTPTGTH 147
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V K G + +G+KDL +LK
Sbjct: 148 FCEVEQMKNGPPVIHSGIKDLKVLK 172
[117][TOP]
>UniRef100_UPI00004C0970 Uricase (EC 1.7.3.3) (Urate oxidase). n=1 Tax=Canis lupus
familiaris RepID=UPI00004C0970
Length = 304
Score = 90.5 bits (223), Expect = 6e-17
Identities = 47/145 (32%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + ++ GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYVYGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V +A++YVE+ PW R +++G+ H H F T
Sbjct: 81 FKGIK-SIETFAMNICEHFLSSFNHVIRAQVYVEEVPWKRFEKNGVKHVHAFIHNPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 140 FCEVEQMRSGPPVIHSGIKDLKVLK 164
[118][TOP]
>UniRef100_Q5FZI9 Uricase n=1 Tax=Canis lupus familiaris RepID=URIC_CANFA
Length = 304
Score = 90.5 bits (223), Expect = 6e-17
Identities = 47/145 (32%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + ++ GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYVYGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V +A++YVE+ PW R +++G+ H H F T
Sbjct: 81 FKGIK-SIETFAMNICEHFLSSFNHVIRAQVYVEEVPWKRFEKNGVKHVHAFIHNPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 140 FCEVEQMRSGPPVIHSGIKDLKVLK 164
[119][TOP]
>UniRef100_Q5I0T2 Uricase n=1 Tax=Xenopus (Silurana) tropicalis RepID=Q5I0T2_XENTR
Length = 304
Score = 90.1 bits (222), Expect = 8e-17
Identities = 41/145 (28%), Positives = 86/145 (59%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ ++ R+G H + E V+ + + +L GDN+ + TDT KNT+Y + +
Sbjct: 21 YGKNAVKVLQIKRNGKQHFIKEIEVSVQLTLKSKKDYLEGDNSDIIPTDTIKNTIYALTK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ TIE++++ +A+HF+ ++ V++ K+++ + PW R++++G+ H H F V
Sbjct: 81 LKGIQ-TIEEFSVEIARHFLTSFNHVTEVKVFINEAPWRRMEKNGMSHVHAFIYSPEGVH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ + G + +G+K+L +LK
Sbjct: 140 FCELQQKRGGQPAIFSGIKELRILK 164
[120][TOP]
>UniRef100_Q7Q4K6 Uricase n=1 Tax=Anopheles gambiae RepID=Q7Q4K6_ANOGA
Length = 326
Score = 90.1 bits (222), Expect = 8e-17
Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ V R G VH + E+ V T + + +L GDN+ + ATD+QKNTVY++A+
Sbjct: 28 YGKDSVKVMHVVRSGLVHTIKEFEVGTKLKLRSQKDYLEGDNSDIVATDSQKNTVYLLAR 87
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP----HDHGFALQG 438
+ K + E++ I L HF+ Y V + I++E+ PW+R+ P H+H F
Sbjct: 88 KHGLK-SPEEFGILLCHHFLSKYSHVEEVSIHIEEYPWSRMGFGTGPYKDLHNHAFVFTP 146
Query: 439 TEVRTVYVTYDKAGTL-DVTAGLKDLSLLK 525
T +R VT + V +GL DL +LK
Sbjct: 147 TAIRYTDVTQKRTEIKPTVISGLTDLRVLK 176
[121][TOP]
>UniRef100_C5M5G3 Uricase n=1 Tax=Candida tropicalis MYA-3404 RepID=C5M5G3_CANTT
Length = 303
Score = 90.1 bits (222), Expect = 8e-17
Identities = 49/149 (32%), Positives = 83/149 (55%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK+ V+ +V +D + V ++E NV ++ E ++ DN+ + TDT KNT+ V
Sbjct: 10 YGKANVKFLKVKKDQSNPTVQEILEANVQVLLRGKFEESYTKADNSSIVPTDTVKNTILV 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A+ + IE++A LA+HF Y V ++ + Q W+++Q +G H H F G
Sbjct: 70 EAKN-TDVWPIERFAAHLAKHFTSKYGHVEGIEVTIVQSKWSKIQLNGKEHAHSFRYDGP 128
Query: 442 EVRTVYVTYDK-AGTLDVTAGLKDLSLLK 525
E R ++ YDK L +T+ +KDL++LK
Sbjct: 129 ETRRTFLNYDKLTKKLQLTSSIKDLTVLK 157
[122][TOP]
>UniRef100_P25688 Uricase n=2 Tax=Mus musculus RepID=URIC_MOUSE
Length = 303
Score = 90.1 bits (222), Expect = 8e-17
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ IE +A+ + +HF+ ++ V++A +YVE+ PW R +++G+ H H F T
Sbjct: 81 LRGIR-NIETFAMNICEHFLSSFNHVTRAHVYVEEVPWKRFEKNGIKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G + +G+KDL +LK
Sbjct: 140 FCEVEQMRNGPPVIHSGIKDLKVLK 164
[123][TOP]
>UniRef100_Q3MHG7 Uricase n=1 Tax=Bos taurus RepID=URIC_BOVIN
Length = 304
Score = 90.1 bits (222), Expect = 8e-17
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLNSRREYLHGDNSDIIPTDTIKNTVQVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V + ++YVE+ PW R +++G+ H H F T
Sbjct: 81 FKGIK-SIETFAMNICEHFLSSFNHVIRVQVYVEEVPWKRFEKNGVKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 140 FCEVEQLRSGPPVIHSGIKDLKVLK 164
[124][TOP]
>UniRef100_UPI000194CDA0 PREDICTED: urate oxidase n=1 Tax=Taeniopygia guttata
RepID=UPI000194CDA0
Length = 320
Score = 89.7 bits (221), Expect = 1e-16
Identities = 48/145 (33%), Positives = 80/145 (55%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ ++ R+ ++G H + E V T + +L G N+ + TDT KN V V+A+
Sbjct: 16 YGKNSIKFLRLHKEGKKHFVKEVEVCTHLRLTSPQEYLEGKNSLVIPTDTIKNIVLVLAK 75
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ ++EQ+AI + HF+ T+ V+ K Y+++ PW R+ + G+PH H F +R
Sbjct: 76 KNGIS-SLEQFAIDICNHFMTTFCQVAYVKTYIQEVPWQRLHEDGVPHIHSFICVPDGIR 134
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
+ G L V AG+KDL L+K
Sbjct: 135 FCEAEQCRNGPLIVFAGIKDLKLMK 159
[125][TOP]
>UniRef100_Q4S7B9 Uricase n=1 Tax=Tetraodon nigroviridis RepID=Q4S7B9_TETNG
Length = 299
Score = 89.7 bits (221), Expect = 1e-16
Identities = 47/145 (32%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R G+ H ++E + I +L+GDN+ + TDT KNTV+ +A+
Sbjct: 16 YGKNAVKVLVIRRHGSHHDIIELKADVQITLKSRKDYLHGDNSDIIPTDTIKNTVHALAK 75
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ TIEQ+++ + HF+ ++ V +A++Y+E+ PW R++++G H H F
Sbjct: 76 LKGVQ-TIEQFSLDICHHFLTSFNHVLRARVYMEEAPWKRLEKNGAEHAHAFINSPEACH 134
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G V +GLKD++LLK
Sbjct: 135 FCDVEQNLNGIPVVHSGLKDMTLLK 159
[126][TOP]
>UniRef100_C1AW86 Uricase n=1 Tax=Rhodococcus opacus B4 RepID=C1AW86_RHOOB
Length = 297
Score = 89.7 bits (221), Expect = 1e-16
Identities = 52/155 (33%), Positives = 80/155 (51%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M+ L + +GK++VRL ++ RD H + + V + + D++ GDN + ATDT
Sbjct: 1 MSQIVLGQNQYGKAEVRLVKITRDTKRHEIEDVTVTSQLRGDLDAVHTAGDNAHVVATDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTVY A+ IE +A+ L +HF + ++ + +EQ W R+ G HDH
Sbjct: 61 QKNTVYAFAR--DGVGAIESFAMRLGKHFTGEFEWITGGRWEIEQYSWARIPVDGEGHDH 118
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
F E R VT D T V +GL ++ +LK
Sbjct: 119 SFVRSSDERRNTVVTIDGDRTW-VVSGLSNMVVLK 152
[127][TOP]
>UniRef100_Q5KBI4 Uricase n=1 Tax=Filobasidiella neoformans RepID=Q5KBI4_CRYNE
Length = 311
Score = 89.7 bits (221), Expect = 1e-16
Identities = 49/150 (32%), Positives = 76/150 (50%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ RV RDG HH+VE+ + +++ ++E ++ DN+ + ATDT KNT + A+
Sbjct: 12 YGKDLVKVARVVRDGEQHHIVEYTLRVLLEGEIETSYTEADNSCVVATDTVKNTCNIFAK 71
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+A+ L HFV Y + K + + W+R+ G PH F G E
Sbjct: 72 TSPYVLDAPVFALHLGLHFVTKYKHIHKCFVDIIGLKWSRISVDGKPHKWSFIRDGDEKA 131
Query: 451 TVYVTYD-----KAGTLDVTAGLKDLSLLK 525
V D A T +V G+KDL +LK
Sbjct: 132 IVECVVDGTAGPDAATANVKIGIKDLLVLK 161
[128][TOP]
>UniRef100_Q0UIT2 Uricase n=1 Tax=Phaeosphaeria nodorum RepID=Q0UIT2_PHANO
Length = 300
Score = 89.7 bits (221), Expect = 1e-16
Identities = 48/147 (32%), Positives = 80/147 (54%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VRL +V +D H +VE + +++ D+E ++ DN+ + ATDTQK T Y++
Sbjct: 9 YGKDNVRLYKVDKDPKTGTHTIVEQTIRILLEGDIETSYTKADNSVIVATDTQKQTTYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ EQ+A + HF+ TYP + A + + Q WTR+ G PH H F G E
Sbjct: 69 AKQHPIDPP-EQFAAIIGDHFIATYPHIHAAHVKIIQHRWTRMNIDGKPHPHSFYRDGEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+R V + + + + ++ L +LK
Sbjct: 128 LRVVESVTREGQGVSIRSKIEKLLVLK 154
[129][TOP]
>UniRef100_C9SP14 Uricase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9SP14_9PEZI
Length = 293
Score = 89.7 bits (221), Expect = 1e-16
Identities = 52/145 (35%), Positives = 80/145 (55%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK VR+ +V +DG V + E V +++ +E ++ DN+ + ATD+ KNT+Y+ A+
Sbjct: 9 YGKDNVRVFKVQKDGPVQTVTEMTVCALLEGAIETSYTVADNSVVVATDSIKNTIYIKAK 68
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
E YA L HF+ TY +S A I V WTR+ G PH H F G E R
Sbjct: 69 EHPINPP-ELYASILGTHFLDTYAHISVANIRVTVHRWTRLDVDGKPHPHSFLRDGEETR 127
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
TV + G + +T+G++ L++LK
Sbjct: 128 TVEARVTRDG-VALTSGIQKLTVLK 151
[130][TOP]
>UniRef100_C0NVE8 Uricase n=1 Tax=Ajellomyces capsulatus G186AR RepID=C0NVE8_AJECG
Length = 256
Score = 89.7 bits (221), Expect = 1e-16
Identities = 52/155 (33%), Positives = 82/155 (52%), Gaps = 4/155 (2%)
Frame = +1
Query: 67 TYALPLHHHGKSKVRLGRVWR--DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
T L +GK VR+ +V R + VH +VE V +++ D+E ++ DN+ + ATD+
Sbjct: 2 TPKLAAARYGKDNVRVYKVHRNEETGVHTVVEMTVCVLLEGDIETSYTKADNSVVVATDS 61
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
KNT+Y++A ++ E +A L HF TYP + A + + W R+ G PH H
Sbjct: 62 MKNTIYIMA-KLYPVTPPELFASILGSHFTATYPHIHTAHVDIVTLRWARMTFDGKPHPH 120
Query: 421 GFALQGTEVRTVYVTYDK--AGTLDVTAGLKDLSL 519
F GTE R V T + +G+ D+T+ +SL
Sbjct: 121 SFLRDGTETRNVSATVSEGNSGSKDITSLTSTISL 155
[131][TOP]
>UniRef100_O74409 Probable uricase n=1 Tax=Schizosaccharomyces pombe RepID=URIC_SCHPO
Length = 296
Score = 89.7 bits (221), Expect = 1e-16
Identities = 48/147 (32%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGR--VWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK+ VR + + H + E +V +++ ++E ++ DN+ + TDTQKNT+YV
Sbjct: 12 YGKTLVRFMKKDICPKTKTHTVYEMDVQSLLTGELEESYTKADNSIVVPTDTQKNTIYVF 71
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ + E +A LA+HFV Y + A + + PWTR++ G PH H F E
Sbjct: 72 AKN-NDVSVPEVFAAKLAKHFVDKYKHIHGAALDITITPWTRMEVQGKPHSHSFIRNPGE 130
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R +V + + DV + LKD+ +LK
Sbjct: 131 TRKTHVVFSEGKGFDVVSSLKDVLVLK 157
[132][TOP]
>UniRef100_B6K6G8 Uricase n=1 Tax=Schizosaccharomyces japonicus yFS275
RepID=B6K6G8_SCHJY
Length = 293
Score = 89.4 bits (220), Expect = 1e-16
Identities = 50/147 (34%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK+KV+ + D VH + E +V T++ ++E ++ DN + TDTQKNTV+V
Sbjct: 9 YGKTKVKFLKKVIDPKTKVHTVYEMDVQTLLKGELEESYTKADNRCVVPTDTQKNTVHVF 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A LA+HFV Y + A I V PW R+Q +G H H F E
Sbjct: 69 AKKFDVSVP-EVFAAHLAKHFVDRYSHIHGAVIDVSLTPWVRLQVNGTDHPHSFIRNPGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R +V + + D+ + +KD+ +LK
Sbjct: 128 CRKTHVEFSEGSGFDICSSVKDILVLK 154
[133][TOP]
>UniRef100_Q8MHW6 Uricase n=2 Tax=Cercopithecinae RepID=URIC_MACFA
Length = 304
Score = 89.4 bits (220), Expect = 1e-16
Identities = 46/145 (31%), Positives = 85/145 (58%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYLHGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE + + + ++F+ ++ V +A++YVE+ PW R++++G+ H H F T
Sbjct: 81 FKGIK-SIEAFGVNICEYFLSSFNHVIRAQVYVEEIPWKRLEKNGVKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 140 FCEVEQLRSGPPVIHSGIKDLKVLK 164
[134][TOP]
>UniRef100_C3UZW8 Uricase n=1 Tax=Perca flavescens RepID=C3UZW8_PERFV
Length = 299
Score = 89.0 bits (219), Expect = 2e-16
Identities = 46/145 (31%), Positives = 86/145 (59%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R+G+ H ++E + + +L GDN+ + TDT KNTV+ +A+
Sbjct: 16 YGKNTVKVLVIRREGSHHFIIELKADVELTLKSRKDYLTGDNSDIIPTDTIKNTVHGLAK 75
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K TIEQ+++ + HF+ ++ V +AK+Y+E+ PW R++++G+ H H F R
Sbjct: 76 LKGVK-TIEQFSLDICLHFLTSFNHVLRAKVYMEEAPWRRLEKNGVEHAHAFIYSPEACR 134
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G V +G+K++++LK
Sbjct: 135 FCDVEQNLNGIPVVHSGVKNMTVLK 159
[135][TOP]
>UniRef100_C5JX06 Uricase n=1 Tax=Ajellomyces dermatitidis SLH14081
RepID=C5JX06_AJEDS
Length = 314
Score = 89.0 bits (219), Expect = 2e-16
Identities = 55/162 (33%), Positives = 85/162 (52%), Gaps = 9/162 (5%)
Frame = +1
Query: 67 TYALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
T L +GK VR+ +V R+ VH +VE V +++ D+E ++ DN+ + ATD+
Sbjct: 2 TSRLAAARYGKDNVRVCKVHRNEKTGVHTVVEMTVCVLLEGDIETSYTKADNSVVVATDS 61
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
KNT+Y++A ++ E +A L HF TYP + A + + WTR+ G PH H
Sbjct: 62 MKNTIYIMA-KLHPVTPPELFASILGSHFTTTYPHIHTAHVDITAIRWTRMTIDGKPHPH 120
Query: 421 GFALQGTEVRTVYVTY-----DKAG--TLDVTAGLKDLSLLK 525
F GT+ R V T K G T+ +T+ + LS+LK
Sbjct: 121 SFFRDGTDTRNVSATVTDGTTTKHGTPTIKLTSSIAALSVLK 162
[136][TOP]
>UniRef100_C4YBD1 Uricase n=1 Tax=Clavispora lusitaniae ATCC 42720 RepID=C4YBD1_CLAL4
Length = 302
Score = 89.0 bits (219), Expect = 2e-16
Identities = 50/149 (33%), Positives = 85/149 (57%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK+ V+ +V +D V ++E N ++ + + ++ DN+ + TDT KNT+ V
Sbjct: 9 YGKANVKFLKVRKDAANPAVQDVLEANCQVLLRGNFDVSYTEADNSPVVPTDTVKNTILV 68
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A++ + IE++A LA+HF Y VS +I + Q WT+ + +G H H F +G
Sbjct: 69 EAKK-TNVWPIERFAAHLAKHFTGKYSHVSGVEITIVQSRWTKYEVNGSLHAHSFRNEGP 127
Query: 442 EVRTVYVTYDKA-GTLDVTAGLKDLSLLK 525
E R ++ Y KA G L +T+ +KDL++LK
Sbjct: 128 ETRRTFLVYSKASGQLSITSSIKDLTVLK 156
[137][TOP]
>UniRef100_P11645 Uricase n=1 Tax=Oryctolagus cuniculus RepID=URIC_RABIT
Length = 300
Score = 89.0 bits (219), Expect = 2e-16
Identities = 46/145 (31%), Positives = 83/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + ++ GDN+ + TDT KNTV+V+A+
Sbjct: 17 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKQDYVYGDNSDIIPTDTIKNTVHVLAK 76
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE +A+ + +HF+ ++ V + +YVE+ PW R++++G+ H H F T
Sbjct: 77 FKGIK-SIEVFAMNICEHFLSSFNHVVRVHVYVEEVPWKRLEKNGVQHVHAFIHTPTGTH 135
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 136 FCEVEQRRSGLPVIHSGIKDLKVLK 160
[138][TOP]
>UniRef100_Q54LT2 Uricase n=1 Tax=Dictyostelium discoideum RepID=URIC_DICDI
Length = 287
Score = 89.0 bits (219), Expect = 2e-16
Identities = 50/150 (33%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMV-EWNVNTMI-DSDMEHAFLNGDNTGMTATDTQKNTVY 258
+ +GK++VR+ RV++ N +H V +++ ++ ++ +L GDN+ + ATDT KNTVY
Sbjct: 7 NRYGKARVRVLRVFKGPNEYHKVFDFDCRVLLRGAEFSETYLTGDNSKVVATDTMKNTVY 66
Query: 259 VVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS-GLPHDHGFALQ 435
V+AQ+ K ++E+Y I L +HF+ TY V+ ++ + + W R++ S G H F +
Sbjct: 67 VIAQKEEFK-SLEEYGILLGKHFLATYSWVNGVEVVMRENQWRRIKTSNGKEQAHSFQ-R 124
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E+ +V VT + + V +G+ DL ++K
Sbjct: 125 DREIHSVTVTSSRDKSPVVVSGIDDLLIMK 154
[139][TOP]
>UniRef100_UPI0000D99A03 PREDICTED: similar to Uricase (Urate oxidase) n=1 Tax=Macaca
mulatta RepID=UPI0000D99A03
Length = 301
Score = 88.6 bits (218), Expect = 2e-16
Identities = 45/145 (31%), Positives = 85/145 (58%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +++GDN+ + TDT KNTV+V+A+
Sbjct: 18 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYVHGDNSDIIPTDTIKNTVHVLAK 77
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE + + + ++F+ ++ V +A++YVE+ PW R++++G+ H H F T
Sbjct: 78 LKGIK-SIEAFGVNICEYFLSSFNHVIRAQVYVEEIPWKRLEKNGVKHVHAFIHTPTGTH 136
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G+KDL +LK
Sbjct: 137 FCEVEQLRSGPPVIHSGIKDLKVLK 161
[140][TOP]
>UniRef100_B8IRU1 Uricase n=1 Tax=Methylobacterium nodulans ORS 2060
RepID=B8IRU1_METNO
Length = 279
Score = 88.6 bits (218), Expect = 2e-16
Identities = 49/145 (33%), Positives = 73/145 (50%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK +VR+ V RDG H + E V M+ + AF + DN+ +TDT KN V +VA
Sbjct: 8 YGKGRVRVMCVHRDGGRHAVRELTVQAMLTGGFDPAFTHADNSTTVSTDTVKNVVNIVA- 66
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
R + E + A+AQ + +Y +V A + + W+R+ G PH H F L G
Sbjct: 67 RETMTLPAEAFCQAVAQRLLDSYAMVETATVTAHETRWSRLSIDGTPHPHAFTLDGNGKS 126
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G L V +GL ++LK
Sbjct: 127 VAKVRMGRGGALTVESGLSGFTILK 151
[141][TOP]
>UniRef100_C1RI51 Uricase n=1 Tax=Cellulomonas flavigena DSM 20109 RepID=C1RI51_9CELL
Length = 300
Score = 88.6 bits (218), Expect = 2e-16
Identities = 53/150 (35%), Positives = 74/150 (49%)
Frame = +1
Query: 76 LPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
L + +GK++VRL RV RD VH + + V T + D GDN + ATDTQKNTV
Sbjct: 8 LGANQYGKAEVRLVRVTRDTPVHEIEDLTVTTQLRGDFAACHTTGDNAHVVATDTQKNTV 67
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
Y A R + E + + LA+HFV + V+ + + W R+ G PHDH F
Sbjct: 68 YAFA-RTHGVGSPEAFLLRLARHFVDGFDQVTGGRFAADVHAWDRIAVDGKPHDHAFVRT 126
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G R V D + V +G ++LK
Sbjct: 127 GAGTRRAVVLVD-GDDVHVVSGFTGATVLK 155
[142][TOP]
>UniRef100_A6REK6 Uricase n=1 Tax=Ajellomyces capsulatus NAm1 RepID=A6REK6_AJECN
Length = 318
Score = 88.6 bits (218), Expect = 2e-16
Identities = 52/155 (33%), Positives = 82/155 (52%), Gaps = 4/155 (2%)
Frame = +1
Query: 67 TYALPLHHHGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
T L +GK VR+ +V R+ H +VE V +++ D+E ++ DN+ + ATD+
Sbjct: 2 TPILAAARYGKDNVRVYKVHRNEETGFHTVVEMTVCVLLEGDIETSYTKADNSVVVATDS 61
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
KNT+Y++A ++ E +A L HF TYP + A + + WTR+ G PH H
Sbjct: 62 MKNTIYIMA-KLHPVTPPELFASILGSHFTTTYPHIHTAHVDIVILRWTRMTFDGKPHPH 120
Query: 421 GFALQGTEVRTV--YVTYDKAGTLDVTAGLKDLSL 519
F GTE R V V+ +G+ D+T+ +SL
Sbjct: 121 SFLRDGTETRNVSAIVSEGNSGSKDITSLTSTISL 155
[143][TOP]
>UniRef100_C4R2A9 Uricase n=1 Tax=Pichia pastoris GS115 RepID=C4R2A9_PICPG
Length = 305
Score = 88.2 bits (217), Expect = 3e-16
Identities = 47/151 (31%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D +H ++E V ++ + ++ DN+ + TDT KNT+ V
Sbjct: 9 YGKDNVKFLKVKKDPRNPKIHEVMEATVRVLLTGAFDESYTEADNSSIVPTDTVKNTILV 68
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ---SGLPHDHGFAL 432
A++ IE +A LA+HF+ Y VS + + Q WTR+ + + +DH F
Sbjct: 69 EAKKF-DIWPIENFAAHLAKHFINKYSWVSAVDVSIHQHRWTRISRENGASKTYDHSFLK 127
Query: 433 QGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G E+R + Y + GT +++G+KDL++LK
Sbjct: 128 DGDELRLSTLQYSRNGTFKLSSGVKDLTVLK 158
[144][TOP]
>UniRef100_Q8MKJ3 Uricase n=1 Tax=Macaca mulatta RepID=URIC_MACMU
Length = 304
Score = 88.2 bits (217), Expect = 3e-16
Identities = 46/145 (31%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V++ + RDG H + E + + + +L+GDN+ + TDT KNTV+V+A+
Sbjct: 21 YGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYLHGDNSDIIPTDTIKNTVHVLAK 80
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K +IE + + + ++F+ ++ V +A++YVE+ PW R++++G+ H H F T
Sbjct: 81 FKGIK-SIEAFGVNICEYFLSSFNHVIRAQVYVEEIPWKRLEKNGVKHVHAFIHTPTGTH 139
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V ++G + +G KDL +LK
Sbjct: 140 FCEVEQLRSGPPVIHSGTKDLKVLK 164
[145][TOP]
>UniRef100_UPI00016E7875 UPI00016E7875 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E7875
Length = 300
Score = 87.8 bits (216), Expect = 4e-16
Identities = 46/145 (31%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R + H ++E + + +L+GDN+ + TDT KNTV+ +A+
Sbjct: 17 YGKNAVKVLVIRRHRSRHDIIELKADVQLTLKSRKDYLHGDNSDIIPTDTIKNTVHALAK 76
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ TIEQ+++ + HF+ ++ V +A++Y+E+ PW R++++G H H F R
Sbjct: 77 LKGVQ-TIEQFSLDICHHFLTSFNHVLRARVYMEEAPWRRLEKNGAEHVHAFIHSPEACR 135
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G V +GLKD++LLK
Sbjct: 136 FCDVEQNLNGVPVVHSGLKDMTLLK 160
[146][TOP]
>UniRef100_UPI00016E7874 UPI00016E7874 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E7874
Length = 299
Score = 87.8 bits (216), Expect = 4e-16
Identities = 46/145 (31%), Positives = 84/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R + H ++E + + +L+GDN+ + TDT KNTV+ +A+
Sbjct: 16 YGKNAVKVLVIRRHRSRHDIIELKADVQLTLKSRKDYLHGDNSDIIPTDTIKNTVHALAK 75
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
+ TIEQ+++ + HF+ ++ V +A++Y+E+ PW R++++G H H F R
Sbjct: 76 LKGVQ-TIEQFSLDICHHFLTSFNHVLRARVYMEEAPWRRLEKNGAEHVHAFIHSPEACR 134
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + G V +GLKD++LLK
Sbjct: 135 FCDVEQNLNGVPVVHSGLKDMTLLK 159
[147][TOP]
>UniRef100_C4DPL0 Uricase n=1 Tax=Stackebrandtia nassauensis DSM 44728
RepID=C4DPL0_9ACTO
Length = 273
Score = 87.8 bits (216), Expect = 4e-16
Identities = 53/150 (35%), Positives = 84/150 (56%), Gaps = 1/150 (0%)
Frame = +1
Query: 76 LPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
L ++ +GK++ R+ R+ RD H + + NV+ + D+ L+GDN+ + TDTQKNTV
Sbjct: 4 LDVNQYGKAETRVVRLCRDTPRHEIRDLNVSIALSGDLTDVHLSGDNSHVVPTDTQKNTV 63
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFAL- 432
Y A+ + +E + + LA+HFV + + A + +++ W RV DH F+
Sbjct: 64 YAFARAGIDQ--VETFGLRLARHFVDEFDPIHGASVDLDEYAWQRV------GDHSFSRG 115
Query: 433 QGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
G E RT ++ YD V+AGLKDL LL
Sbjct: 116 SGGETRTAHIGYD-GDVATVSAGLKDLLLL 144
[148][TOP]
>UniRef100_A7SYI1 Uricase n=1 Tax=Nematostella vectensis RepID=A7SYI1_NEMVE
Length = 297
Score = 87.8 bits (216), Expect = 4e-16
Identities = 47/146 (32%), Positives = 83/146 (56%), Gaps = 1/146 (0%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMV-EWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
+GK+ VRL ++ R ++H + E V + + +LNGDN+ + TDTQKNT+Y +A
Sbjct: 13 YGKTGVRLLKIKRRSTLYHEIKELEVAVELKLRSKKDYLNGDNSDVIPTDTQKNTIYALA 72
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
++ +IE++ + + ++F+ T+ V IY+ + PW RV+Q G+ H H F +
Sbjct: 73 KKHPLD-SIEEFGLHVCKYFLDTHKHVDAVVIYINEAPWQRVKQGGIGHAHAFIMTPDVQ 131
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V++ + V GL+D+ +LK
Sbjct: 132 RFCEVSHVRGDEPKVFGGLRDMKVLK 157
[149][TOP]
>UniRef100_A4QSS8 Uricase n=1 Tax=Magnaporthe grisea RepID=A4QSS8_MAGGR
Length = 295
Score = 87.8 bits (216), Expect = 4e-16
Identities = 52/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Frame = +1
Query: 73 ALPLHHHGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQK 246
+L +GK VR+ +V R+ + E V +++ +++ +F DN+ + ATD+ K
Sbjct: 3 SLSAARYGKDNVRVYKVHRNAETGQQSVTEMTVCCLLEGEIDASFTKADNSVVVATDSIK 62
Query: 247 NTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGF 426
NT+Y+ A R + E YA L QHF+ TYP + A + V WTR+ G PH H F
Sbjct: 63 NTIYIKA-RETPVNPPELYASILGQHFIDTYPHIHTAHVDVIVHRWTRMTIDGQPHPHSF 121
Query: 427 ALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G E RTV + L + +G+ LS+LK
Sbjct: 122 FRDGQETRTVGAVVRRGSGLALRSGIAGLSVLK 154
[150][TOP]
>UniRef100_Q3S562 Uricase (Fragment) n=1 Tax=Protopterus annectens RepID=Q3S562_PROAN
Length = 292
Score = 87.4 bits (215), Expect = 5e-16
Identities = 45/145 (31%), Positives = 79/145 (54%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R+G H++ E VN + + +L GDN + DT KNTV+ +A+
Sbjct: 9 YGKNAVKVLHIRREGKQHYIKEMEVNVQLTLNARKEYLYGDNADIIPIDTIKNTVHALAK 68
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
K TIE +A+ + HF+ ++ V + +Y+E+ PW ++Q++G H H F VR
Sbjct: 69 LRGVK-TIEHFAMDICNHFLTSFRHVRRVHVYIEEAPWRKLQKNGTGHVHAFIYSPEAVR 127
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + +G+KD+ +LK
Sbjct: 128 FCNVEQYLNEPPVIHSGMKDMKVLK 152
[151][TOP]
>UniRef100_B2WF19 Uricase n=1 Tax=Pyrenophora tritici-repentis Pt-1C-BFP
RepID=B2WF19_PYRTR
Length = 300
Score = 87.4 bits (215), Expect = 5e-16
Identities = 48/147 (32%), Positives = 80/147 (54%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VRL +V +D H ++E V +++ D++ ++ DN+ + ATDTQK T Y++
Sbjct: 9 YGKDNVRLYKVDKDPKTGTHKVIEQTVCVLLEGDIDVSYTKADNSVIVATDTQKQTTYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ EQ+A + HFVRTYP + A + + Q WTR+ G H H F G E
Sbjct: 69 AKQHPIDPP-EQFAAIIGDHFVRTYPHIHAAHVKIIQHRWTRMTIDGKDHPHSFYRDGEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+R V + + + + ++ L +LK
Sbjct: 128 IRVVESITREGHGVSIRSKIEKLLVLK 154
[152][TOP]
>UniRef100_UPI0001B55CF5 putative uricase n=1 Tax=Streptomyces sp. C RepID=UPI0001B55CF5
Length = 305
Score = 87.0 bits (214), Expect = 7e-16
Identities = 51/157 (32%), Positives = 82/157 (52%), Gaps = 3/157 (1%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTA 231
M+ + L + +GK++ R+ V R DG+ + + NV+ + + L GDN
Sbjct: 1 MSKHVLGQNQYGKAENRIVVVTRKGSDGSWAEIRDLNVSVALRGEFRDVHLTGDNANCLP 60
Query: 232 TDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP 411
TDT KNTVY + + E + I LA+HFV + + +A+I +E+ W R+
Sbjct: 61 TDTTKNTVYAFGKEHGI-ASPEAFGILLAKHFVSSQAPIREAQIRIEEFAWERIPVPTRK 119
Query: 412 HDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLL 522
H F +G EVRT +TY + L V +GLKDL+++
Sbjct: 120 EQHSFVRKGQEVRTAQITYSETTGLQVISGLKDLTVM 156
[153][TOP]
>UniRef100_C5GSN2 Uricase n=1 Tax=Ajellomyces dermatitidis ER-3 RepID=C5GSN2_AJEDR
Length = 319
Score = 87.0 bits (214), Expect = 7e-16
Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
Frame = +1
Query: 67 TYALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
T L +GK VR+ +V R+ VH +VE V +++ D+E ++ DN+ + ATD+
Sbjct: 2 TSRLAAARYGKDNVRVCKVHRNEKTGVHTVVEMTVCVLLEGDIETSYTKADNSVVVATDS 61
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
KNT+Y++A ++ E +A L HF TYP + A + + WTR+ G PH H
Sbjct: 62 MKNTIYIMA-KLHPVTPPELFASILGSHFTTTYPHIHTAHVDITAIRWTRMTIDGKPHPH 120
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVT 495
F GT+ R V T T T
Sbjct: 121 SFFRDGTDTRNVSATVTDGTTTTTT 145
[154][TOP]
>UniRef100_C4RL78 Uricase n=1 Tax=Micromonospora sp. ATCC 39149 RepID=C4RL78_9ACTO
Length = 284
Score = 86.7 bits (213), Expect = 9e-16
Identities = 52/146 (35%), Positives = 81/146 (55%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+ +GK++VR+ V RDG+ H + + +V T + D++ L GDN+ + TD+QKNTVY
Sbjct: 8 NRYGKAEVRVVHVARDGDRHTLRDLDVRTALAGDLDATHLTGDNSQVLPTDSQKNTVYAF 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A R + E +A+ LA+HFV + V A++ V++ W R+ H F G +
Sbjct: 68 A-REHGVASPEAFALLLARHFVHSQAAVRHARVAVQEFGWQRL------GPHSFQRDGAQ 120
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLL 522
RT V+YD T V +GL L L+
Sbjct: 121 TRTATVSYD-GDTAQVVSGLTGLVLM 145
[155][TOP]
>UniRef100_UPI000187D40B hypothetical protein MPER_10554 n=1 Tax=Moniliophthora perniciosa
FA553 RepID=UPI000187D40B
Length = 185
Score = 85.9 bits (211), Expect = 2e-15
Identities = 55/167 (32%), Positives = 86/167 (51%), Gaps = 5/167 (2%)
Frame = +1
Query: 40 ASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNT 219
+S STT+ ++A +GK KVR+ RV R+G +HH+VE+NV +++ D++ L
Sbjct: 2 SSTSTTSYLSHA----RYGKDKVRVLRVVREGALHHIVEYNVTVLVEGDIDIRQL----- 52
Query: 220 GMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
KN Y +A+ E++A+ L H V Y + KA + +EQ W+R+
Sbjct: 53 ------CLKNITYYLAKISPHILIPERFALHLGTHLVSKYGHLHKAFVTIEQLRWSRIDV 106
Query: 400 SGLPHDHGFALQGTEVRTVYVTYDKAGTLD-----VTAGLKDLSLLK 525
+G H+H F G E R V V D + D V +G+ DL +LK
Sbjct: 107 NGKQHNHSFWRDGDEKRVVKVEVDASAGKDKIVGKVASGISDLLVLK 153
[156][TOP]
>UniRef100_B4K8G4 Uricase n=1 Tax=Drosophila mojavensis RepID=B4K8G4_DROMO
Length = 335
Score = 85.9 bits (211), Expect = 2e-15
Identities = 55/181 (30%), Positives = 92/181 (50%), Gaps = 15/181 (8%)
Frame = +1
Query: 28 LPTRASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLN 207
LPT + + Y + +GK V++ + R G VH + E V T + ++
Sbjct: 14 LPTTVVKDQSQL--YEITNKGYGKDAVKVMHINRKGRVHSIQELEVGTHLKLYSSKDYMQ 71
Query: 208 GDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWT 387
G+N+ + ATD+QKNTVY++A++ + + E++A+ LA HF++TYP V +A ++VE PW
Sbjct: 72 GNNSDVVATDSQKNTVYLLAKKHGIE-SPEKFALLLASHFLKTYPHVEQAHVHVEAYPWQ 130
Query: 388 RVQQSGLP--------------HDHGFALQGTEVRTVYVTYDKAGTL-DVTAGLKDLSLL 522
R++Q H+H F T + V + V +G+KDL +L
Sbjct: 131 RMEQEHCQVKDGDSQSNCRRQLHNHAFIFTPTAMHYCDVIMSQNDPKPTVMSGIKDLRVL 190
Query: 523 K 525
K
Sbjct: 191 K 191
[157][TOP]
>UniRef100_P78609 Uricase n=1 Tax=Pichia jadinii RepID=URIC_PICJA
Length = 303
Score = 85.9 bits (211), Expect = 2e-15
Identities = 46/148 (31%), Positives = 80/148 (54%), Gaps = 3/148 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D ++E V +++ + ++ DN+ + TDT KNT+ V
Sbjct: 10 YGKDNVKFLKVKKDPQNPKKQEVMEATVTCLLEGGFDTSYTEADNSSIVPTDTVKNTILV 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
+A + ++ IE++A LA HFV Y VS + + Q W + G PHDH F +G
Sbjct: 70 LA-KTTEIWPIERFAAKLATHFVEKYSHVSGVSVKIVQDRWVKYAVDGKPHDHSFIHEGG 128
Query: 442 EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E R + Y ++G +++ +KDL++LK
Sbjct: 129 EKRITDLYYKRSGDYKLSSAIKDLTVLK 156
[158][TOP]
>UniRef100_Q5ACV3 Uricase n=1 Tax=Candida albicans RepID=Q5ACV3_CANAL
Length = 303
Score = 85.5 bits (210), Expect = 2e-15
Identities = 47/149 (31%), Positives = 82/149 (55%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D + V ++E NV ++ + ++ DN+ + TDT KNT+ V
Sbjct: 10 YGKGNVKFLKVKKDPSNPTVQDVLEANVQVLLRGKFDESYTKADNSSIVPTDTVKNTILV 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A + + IE++A LA+HF Y V ++ + Q W++++ G H H F +G
Sbjct: 70 EA-KTTDVWPIERFAAHLAKHFTTKYGHVDGIEVTIIQAKWSKIKLEGKEHAHSFKHEGP 128
Query: 442 EVRTVYVTYDK-AGTLDVTAGLKDLSLLK 525
E R Y+ YDK L +++ +KDL++LK
Sbjct: 129 ETRRTYLNYDKHTKKLQLSSSIKDLTVLK 157
[159][TOP]
>UniRef100_B9WA75 Uricase n=1 Tax=Candida dubliniensis CD36 RepID=B9WA75_CANDC
Length = 303
Score = 85.5 bits (210), Expect = 2e-15
Identities = 47/149 (31%), Positives = 82/149 (55%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D + V ++E NV ++ + ++ DN+ + TDT KNT+ V
Sbjct: 10 YGKGNVKFLKVKKDPSNPTVQDVLEANVQVLLRGKFDESYTKADNSSIVPTDTVKNTILV 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A + + IE++A LA+HF Y V ++ + Q W++++ G H H F +G
Sbjct: 70 EA-KTTDVWPIERFAAHLAKHFTSKYGHVDGIEVTIIQAKWSKIRLEGKEHAHSFKHEGP 128
Query: 442 EVRTVYVTYDK-AGTLDVTAGLKDLSLLK 525
E R Y+ YDK L +++ +KDL++LK
Sbjct: 129 ETRRTYLNYDKHTKKLQLSSSIKDLTVLK 157
[160][TOP]
>UniRef100_Q3S563 Uricase (Fragment) n=1 Tax=Salmo salar RepID=Q3S563_SALSA
Length = 292
Score = 84.3 bits (207), Expect = 5e-15
Identities = 42/145 (28%), Positives = 83/145 (57%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK+ V++ + R+G H++ E N + +L GDN+ + TDT KNTV+ +A
Sbjct: 9 YGKNLVKVLYIRREGTHHYITELTANVELTLKSRKDYLTGDNSDIIPTDTVKNTVHALA- 67
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVR 450
++ TIEQ+A+ +++HF+ + V++ + +E+ PW R++++G+ H H F R
Sbjct: 68 KLKGVLTIEQFAMDISKHFLTAFKHVTRVNVKIEEAPWRRLEKNGVEHVHAFIYGPESCR 127
Query: 451 TVYVTYDKAGTLDVTAGLKDLSLLK 525
V + + + +G+K++ +LK
Sbjct: 128 FCEVEQNLNESPILHSGVKNMKVLK 152
[161][TOP]
>UniRef100_B6HS12 Uricase n=1 Tax=Penicillium chrysogenum Wisconsin 54-1255
RepID=B6HS12_PENCW
Length = 302
Score = 84.3 bits (207), Expect = 5e-15
Identities = 47/153 (30%), Positives = 79/153 (51%), Gaps = 2/153 (1%)
Frame = +1
Query: 73 ALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQK 246
AL +GK VR+ +V RD + +VE V +++ D+E ++ DN+ + ATD+ K
Sbjct: 3 ALAAARYGKDNVRVCKVHRDEKTGIQTVVEMTVCVLLEGDIETSYTKADNSVVVATDSIK 62
Query: 247 NTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGF 426
NTV++ A++ + E + L HF+ Y + A + + W R+ G PH H F
Sbjct: 63 NTVFITAKQ-NPVTPPELFGSILGTHFIEKYSHIHAAHVNIVTHRWVRMDIDGKPHPHSF 121
Query: 427 ALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
GTE R V V + +D+ + + L++LK
Sbjct: 122 IKPGTETRDVQVDVIEGKGIDINSAINGLTVLK 154
[162][TOP]
>UniRef100_A6S030 Uricase n=1 Tax=Botryotinia fuckeliana B05.10 RepID=A6S030_BOTFB
Length = 302
Score = 84.3 bits (207), Expect = 5e-15
Identities = 48/147 (32%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD + E V +++ ++ ++ DN+ + ATD+ KNTVY+
Sbjct: 9 YGKDNVRVYKVDRDEQTGTQTVTEMTVCVLLEGAIDVSYTKADNSVVVATDSMKNTVYIK 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ S E +A L HF+ TYP ++ A I + WTR+ G PH H F G+E
Sbjct: 69 AKEHSVTPP-ELFASILGTHFIETYPHLTAASIKIVTHRWTRMTIDGKPHPHSFYRDGSE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V + +D+ +G+ L +LK
Sbjct: 128 TRNVDAVIKRGKGIDIRSGIVGLLVLK 154
[163][TOP]
>UniRef100_A2QD69 Uricase n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2QD69_ASPNC
Length = 302
Score = 84.3 bits (207), Expect = 5e-15
Identities = 47/147 (31%), Positives = 78/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V +VE V +++ D++ ++ DN+ + ATD+ KNT+Y+
Sbjct: 10 YGKDNVRVYKVHRDEKTGVQTVVEMTVCVLLEGDIDTSYTKADNSVIVATDSIKNTIYIT 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E + L HF+ Y + A + + WTR+ G PH H F G E
Sbjct: 70 AKQ-NPVTPPELFGSILGSHFITKYNHIHAAHVNIITHRWTRMTIDGKPHPHSFLRDGEE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +D+T+ L L++LK
Sbjct: 129 TRNVQVDVVEGKGVDITSSLAKLTVLK 155
[164][TOP]
>UniRef100_A1DGX7 Uricase n=1 Tax=Neosartorya fischeri NRRL 181 RepID=A1DGX7_NEOFI
Length = 302
Score = 84.3 bits (207), Expect = 5e-15
Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD--GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V +VE V +++ ++E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKDNVRVYKVHRDEKSGVQTVVEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E + L HF++ Y + A ++ WTR+ G PH H F E
Sbjct: 70 AKQ-HPVTPPELFGSILGTHFIQKYKHIHAAHAHIITHRWTRMNIDGKPHPHSFVRDSEE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V K +D+ + + L++LK
Sbjct: 129 TRNVQVDVTKGAGIDIKSSISGLTVLK 155
[165][TOP]
>UniRef100_B2AXQ3 Uricase n=1 Tax=Podospora anserina RepID=B2AXQ3_PODAN
Length = 296
Score = 84.0 bits (206), Expect = 6e-15
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDG--NVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V +D + E V +++ +E ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVYKVHKDEATGTQSVTEMTVCCLLEGQIETSYTEADNSVVVATDSIKNTIYIK 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E YA L QHF+ YP ++ A I V WTR+ G PH H F G E
Sbjct: 69 AKEHPVNPP-ELYAAHLGQHFLDKYPHINAANIKVIVHRWTRINIDGKPHPHSFYRDGNE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V + +++ + ++ LS+LK
Sbjct: 128 TRNVEARVSREAGIELKSAIQGLSVLK 154
[166][TOP]
>UniRef100_UPI0000157CC8 Uricase n=2 Tax=Arthrobacter globiformis RepID=UPI0000157CC8
Length = 302
Score = 83.6 bits (205), Expect = 8e-15
Identities = 53/162 (32%), Positives = 83/162 (51%)
Frame = +1
Query: 40 ASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNT 219
A+ T+ L + +GK++VRL +V R+ H + + NV + + D E A GDN
Sbjct: 3 ATAETSTGTKVVLGQNQYGKAEVRLVKVTRNTARHEIQDLNVTSQLRGDFEAAHTAGDNA 62
Query: 220 GMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
+ ATDTQKNTVY A+ T E++ + L +HF + V+ + +Q W R+
Sbjct: 63 HVVATDTQKNTVYAFAR--DGFATTEEFLLRLGKHFTEGFDWVTGGRWAAQQFFWDRIND 120
Query: 400 SGLPHDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
HDH F+ +EVRT V + AG++ L++LK
Sbjct: 121 ----HDHAFSRNKSEVRTA-VLEISGSEQAIVAGIEGLTVLK 157
[167][TOP]
>UniRef100_UPI000050FD34 COG3648: Uricase (urate oxidase) n=1 Tax=Brevibacterium linens BL2
RepID=UPI000050FD34
Length = 294
Score = 83.6 bits (205), Expect = 8e-15
Identities = 52/156 (33%), Positives = 83/156 (53%), Gaps = 1/156 (0%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M+ L + +GK++ RL RV+RD H + + NV + + D E A G+N + ATDT
Sbjct: 1 MSKVKLTTNQYGKAENRLMRVYRDSERHEIRDLNVTSQLWGDFETAHTEGNNEHVVATDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTV+ A+ + + EQ+ + L +HF ++ V+ + E+ W+R+ H+H
Sbjct: 61 QKNTVFAKAKELG-VTSPEQFLLGLGEHFTSSFDWVTGGRWAAEEYGWSRIND----HNH 115
Query: 421 GFALQGTEVRTVYVTYD-KAGTLDVTAGLKDLSLLK 525
F E RT +T D A TL +G L++LK
Sbjct: 116 SFYKSAPETRTAVLTRDGDASTL--ISGFYGLTVLK 149
[168][TOP]
>UniRef100_UPI0001745B8C urate oxidase n=1 Tax=Verrucomicrobium spinosum DSM 4136
RepID=UPI0001745B8C
Length = 279
Score = 83.2 bits (204), Expect = 1e-14
Identities = 45/146 (30%), Positives = 79/146 (54%)
Frame = +1
Query: 88 HHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVA 267
++GK++VRL +V RDG VH + E V ++ + ++ +GDN+ + TDT KN + V+A
Sbjct: 7 NYGKARVRLCKVLRDGPVHSVKEITVRIALEGEFAASYQSGDNSCIVPTDTMKNAINVLA 66
Query: 268 QRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEV 447
E +A +A HF+ Y V+K + +E++ W R+ G+PH H F
Sbjct: 67 YN-HLGVDNEPFAQTVADHFLNRYAQVTKVVVEIEERSWNRLVVGGVPHPHSFTQTQRAT 125
Query: 448 RTVYVTYDKAGTLDVTAGLKDLSLLK 525
+ ++ T + +G++ L+LLK
Sbjct: 126 PLARLVQTRSST-SLESGVQGLTLLK 150
[169][TOP]
>UniRef100_Q0CXR4 Uricase n=1 Tax=Aspergillus terreus NIH2624 RepID=Q0CXR4_ASPTN
Length = 301
Score = 83.2 bits (204), Expect = 1e-14
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V +D V +VE V +++ D++ ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVYKVHKDEKTGVQTVVEMTVCVLLEGDIDTSYTKADNSVIVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E + L HF++ YP + A ++ WTR+ G PH H F E
Sbjct: 69 AKQ-NPVTPPELFGTILGNHFIQKYPHIHAAHAHIITHRWTRLNIDGKPHPHSFYRDSEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +D+ + L L++LK
Sbjct: 128 KRNVQVDVVEGQGVDIRSSLSGLTVLK 154
[170][TOP]
>UniRef100_C4JIY5 Uricase n=1 Tax=Uncinocarpus reesii 1704 RepID=C4JIY5_UNCRE
Length = 328
Score = 82.8 bits (203), Expect = 1e-14
Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTAT 234
MAT L +GK V++ +V RD H + E V ++ D+E ++ DN+ + AT
Sbjct: 1 MAT-KLAAARYGKENVKVCKVHRDAKSGTHEVTELTVAVSLEGDIESSYTKADNSVVVAT 59
Query: 235 DTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPH 414
D+ KNT+Y++A++ S E +A + HF+ TY + A + V WTR+ G PH
Sbjct: 60 DSMKNTIYLLAKQHSVTPP-ELFASIVGTHFIETYNHIHAAHVRVVVHRWTRMNADGKPH 118
Query: 415 DHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
H F GT+VR + + + + L +LK
Sbjct: 119 PHAFLRDGTDVRVAEAYVVDGKGVKIKSSISGLLVLK 155
[171][TOP]
>UniRef100_A1SFS3 Uricase n=1 Tax=Nocardioides sp. JS614 RepID=A1SFS3_NOCSJ
Length = 289
Score = 82.4 bits (202), Expect = 2e-14
Identities = 56/163 (34%), Positives = 81/163 (49%), Gaps = 4/163 (2%)
Frame = +1
Query: 49 STTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMT 228
+TT+ + L + +GK++VRL RV R H + + + T + D E +GDN+ +
Sbjct: 2 ATTDGSRIVLGANQYGKAEVRLLRVDRASERHTIEDLGITTQLRGDFEACHTHGDNSQVV 61
Query: 229 ATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGL 408
TDTQKNT+ A+ E + LA+HF + V+ + E W R+ GL
Sbjct: 62 PTDTQKNTIQAFAR--DGIGAPEHLLLRLARHFTDGFAWVTGGRFDAESYAWERI---GL 116
Query: 409 P----HDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
P HDH F G E RT V D + VTAGL D ++LK
Sbjct: 117 PDGSGHDHSFVRTGRETRTATVEVD-GDEVVVTAGLTDCTVLK 158
[172][TOP]
>UniRef100_UPI000023EC9F hypothetical protein FG04126.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023EC9F
Length = 302
Score = 82.0 bits (201), Expect = 2e-14
Identities = 46/147 (31%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD + V + E V +++ ++E ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVCKVDRDSSTGVQTVTEMTVCCLLEGEIETSYTQADNSVVVATDSIKNTIYIT 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E YA L HF+ Y + A + V+ W R+ G PH H F G E
Sbjct: 69 AKENPVNPP-ELYASILGSHFIEKYKHIHVANVSVKTVRWARLDVDGKPHPHSFFKDGEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +++ + L L++LK
Sbjct: 128 TRNVEVRVSRQEGIEIKSSLVGLTVLK 154
[173][TOP]
>UniRef100_Q1J399 Uricase n=1 Tax=Deinococcus geothermalis DSM 11300
RepID=Q1J399_DEIGD
Length = 293
Score = 82.0 bits (201), Expect = 2e-14
Identities = 52/150 (34%), Positives = 79/150 (52%)
Frame = +1
Query: 76 LPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTV 255
L +++GK++V L +V RD H + E V + D A GDNT + ATDT +NT+
Sbjct: 16 LGANNYGKAEVNLMKVKRDSERHEIRELQVRVALIGDFAAAHEQGDNTDLLATDTVRNTI 75
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
Y +A+ Q + E + L HFV T P V+ + + W R+Q G H+H F Q
Sbjct: 76 YGLAKEGFQ-ASPEAFGKELISHFVTTGPKVTGGFMEFTEYLWERIQVGGEGHNHAFVRQ 134
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+ RT V + T +T+GL++L +LK
Sbjct: 135 MPQ-RTGRVESEDGKTFKITSGLQNLYVLK 163
[174][TOP]
>UniRef100_Q9UVD5 Uricase n=1 Tax=Nilaparvata lugens yeast-like symbiont
RepID=Q9UVD5_9ASCO
Length = 296
Score = 82.0 bits (201), Expect = 2e-14
Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V + E + +I+ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVLKVSRDAGIGVQTVTEMTIRCLIEGDIEASYTGADNSSVVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A ++ HF++ Y + A + + W R+ G PH H F E
Sbjct: 69 AKQHRVNPP-ELFASIISSHFIQKYSHIHVADVDIITHRWLRMDVDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+V + + + + + LSLLK
Sbjct: 128 TRNVHVNAKRQDGIAIASSIVGLSLLK 154
[175][TOP]
>UniRef100_Q9HGJ1 Uricase (Fragment) n=1 Tax=Beauveria bassiana RepID=Q9HGJ1_BEABA
Length = 277
Score = 82.0 bits (201), Expect = 2e-14
Identities = 42/129 (32%), Positives = 69/129 (53%)
Frame = +1
Query: 139 VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALA 318
VH + E V +++ +E ++ DN+ + ATD+ KNTV+++A++ E +A L
Sbjct: 2 VHTVTETVVCVLLEGAIETSYTQADNSVVVATDSMKNTVFILAKQ-HPVTPPELFAATLG 60
Query: 319 QHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVRTVYVTYDKAGTLDVTA 498
HF+ Y + A + + K W R+ G PH H F +G E R V + G + V +
Sbjct: 61 AHFIEKYSHIHVANVDIVTKRWVRMHVDGRPHPHSFVKEGEEKRNVRTRVSRRGGIAVNS 120
Query: 499 GLKDLSLLK 525
GL DL++LK
Sbjct: 121 GLSDLTVLK 129
[176][TOP]
>UniRef100_Q6BYT1 Uricase n=1 Tax=Debaryomyces hansenii RepID=Q6BYT1_DEBHA
Length = 304
Score = 82.0 bits (201), Expect = 2e-14
Identities = 45/149 (30%), Positives = 81/149 (54%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRD---GNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V ++ ++E NV ++ + + ++ DN + TDT KNT+ +
Sbjct: 10 YGKGNVKFLKVKKNPHNSKEQDVLEANVQVLLKGNFDVSYTKADNAPIVPTDTVKNTILI 69
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
A + + IE++A LA+HF Y VS ++ + Q WT+ + G H H F +G
Sbjct: 70 EA-KTTNVWPIERFAAHLAKHFTEKYAHVSGIEVSIVQSKWTKYEVDGKIHPHSFKHEGP 128
Query: 442 EVRTVYVTYDKAG-TLDVTAGLKDLSLLK 525
E R ++TY ++ L +T+ +KDL++LK
Sbjct: 129 ETRRTFLTYCRSNKKLTITSSIKDLTVLK 157
[177][TOP]
>UniRef100_Q53IP7 Uricase n=1 Tax=Gibberella fujikuroi RepID=Q53IP7_GIBFU
Length = 302
Score = 82.0 bits (201), Expect = 2e-14
Identities = 46/147 (31%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD + + + E V +++ ++E ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVCKVDRDASTGIQTVTEMTVCCLLEGEIETSYTKADNSVVVATDSIKNTIYIT 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E YA L HF+ Y + A I V+ W R++ G PH H F G E
Sbjct: 69 AKQNPVNPP-ELYASILGSHFIEKYSHIHVANINVKTVRWQRLEVDGKPHPHSFFKDGEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + + + + L L++LK
Sbjct: 128 TRNVEVRVSRQEGIQIKSSLVGLTVLK 154
[178][TOP]
>UniRef100_C7Z9I4 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z9I4_NECH7
Length = 302
Score = 82.0 bits (201), Expect = 2e-14
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD + + E V +++ ++E ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVCKVDRDATTGIQTVTEMTVCCLLEGEIETSYTEADNSVVVATDSIKNTIYIT 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E YA L HF++ Y + A + V+ WTR+ G PH H F G E
Sbjct: 69 AKENPVNPP-ELYASILGSHFIQKYKHIHVANVNVKTVRWTRLAVDGKPHPHSFFKDGEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + + + + + L++LK
Sbjct: 128 TRNVEVRVSRQDGIQIKSSIVGLTVLK 154
[179][TOP]
>UniRef100_A7E484 Uricase n=1 Tax=Sclerotinia sclerotiorum 1980 UF-70
RepID=A7E484_SCLS1
Length = 302
Score = 82.0 bits (201), Expect = 2e-14
Identities = 47/147 (31%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD + E V +++ ++ ++ DN+ + ATD+ KNTVY+
Sbjct: 9 YGKDNVRVYKVERDEQTGTQTVTEMTVCVLLEGAIDVSYTKADNSVVVATDSMKNTVYIK 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E +A L HF+ TYP ++ A I + WTR+ G PH H F G E
Sbjct: 69 AKE-HPVTPPELFASILGTHFIDTYPHLTAANIKIITHRWTRMTIDGKPHPHSFYRDGNE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V + +D+ +G+ L +LK
Sbjct: 128 TRNVEAVIKRGKGIDIRSGIVGLLVLK 154
[180][TOP]
>UniRef100_Q9HGJ5 Uricase n=1 Tax=Laodelphax striatellus yeast-like symbiont
RepID=Q9HGJ5_9ASCO
Length = 296
Score = 81.6 bits (200), Expect = 3e-14
Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V + E + +I+ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVLKVSRDAGIGVQTVTEMTIRCLIEGDIEASYTGADNSSVVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A ++ HF++ Y + A + + W R+ G PH H F E
Sbjct: 69 AKQHRVNPP-ELFASIISSHFIQKYSHIHVADVDIVTHRWLRMDVDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+V + + + + + LSLLK
Sbjct: 128 TRNVHVYAKRQDGIAIASSIVGLSLLK 154
[181][TOP]
>UniRef100_Q9HGJ4 Uricase n=1 Tax=Ricania japonica yeast-like symbiont
RepID=Q9HGJ4_9ASCO
Length = 296
Score = 81.6 bits (200), Expect = 3e-14
Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V + E + +I+ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVLKVSRDAGIGVQTVTEMTIRCLIEGDIEASYTGADNSSVVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A ++ HF++ Y + A + + W R+ G PH H F E
Sbjct: 69 AKQHRVNPP-ELFASIISSHFIQKYSHIHVADVDIVTHRWLRMDVDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+V + + + + + LSLLK
Sbjct: 128 TRNVHVHAKRQDGIAIASSIVGLSLLK 154
[182][TOP]
>UniRef100_Q9HGJ2 Uricase n=1 Tax=Cerataphis fransseni yeast-like symbiont
RepID=Q9HGJ2_9ASCO
Length = 296
Score = 81.6 bits (200), Expect = 3e-14
Identities = 45/147 (30%), Positives = 78/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V + E + +I+ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVLKVSRDAGTGVQTVAEMTIRCLIEGDIEASYTGADNSSVVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E +A L+ HF++ Y + A + + W R+ G PH H F E
Sbjct: 69 AKQ-HRVHPPELFASILSTHFIQKYSHIHVADVDIVTHRWLRMDIDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+V + + + + + LSLLK
Sbjct: 128 TRNVHVHAKRQDGIAIASSIVGLSLLK 154
[183][TOP]
>UniRef100_B0XS86 Uricase n=2 Tax=Aspergillus fumigatus RepID=B0XS86_ASPFC
Length = 302
Score = 81.3 bits (199), Expect = 4e-14
Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V +VE + +++ ++E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKDNVRVYKVHRDEKTGVQTVVEMTICVLLEGEIETSYTKADNSVIVATDSIKNTIYIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E + L HF++ Y + A ++ WTR+ G PH H F E
Sbjct: 70 AKQ-HPVTPPELFGSILGTHFIQKYKHIHAAHAHIITHRWTRMNIDGKPHPHSFVRDSEE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +D+ + + L++LK
Sbjct: 129 TRNVQVDVTEGAGIDIKSSITGLTVLK 155
[184][TOP]
>UniRef100_Q3S561 Uricase (Fragment) n=1 Tax=Gadus morhua RepID=Q3S561_GADMO
Length = 235
Score = 80.9 bits (198), Expect = 5e-14
Identities = 45/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 106 VRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQRMSQK 285
V++ + R G H +VE + + + + GDN + TDT KNTV+ +A+ +
Sbjct: 2 VKVLYIRRKGAHHSIVELRADVELTLNSRKDYTTGDNADIIPTDTIKNTVHGLAKIKGVE 61
Query: 286 CTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVRTVYVT 465
TIEQ+++ L HF+ + V +A +Y+E+ PW R++++G+ H H F L R V
Sbjct: 62 -TIEQFSLDLCHHFLTAFTHVVRASVYMEEAPWKRLEKNGVEHSHAFILSPETSRFCDVK 120
Query: 466 YDKAGTLDVTAGLKDLSLLK 525
+ V +GLKD+ +LK
Sbjct: 121 QNLNDIPVVHSGLKDMKVLK 140
[185][TOP]
>UniRef100_B4N0U8 Uricase n=1 Tax=Drosophila willistoni RepID=B4N0U8_DROWI
Length = 346
Score = 80.9 bits (198), Expect = 5e-14
Identities = 47/130 (36%), Positives = 76/130 (58%), Gaps = 3/130 (2%)
Frame = +1
Query: 19 IKPLPTRASNSTTNMAT---YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDM 189
+KPL +S S + T Y + H +GK V++ V R G VH + E+ V T +
Sbjct: 3 VKPLQKASSLSLSQNPTHSQYEITDHGYGKDAVKVLHVSRKGPVHTIHEFEVGTHLKLYS 62
Query: 190 EHAFLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYV 369
+ + G+N+ + ATD+QKNTVY++A++ + + E +A+ LA+HF+ Y V +A ++V
Sbjct: 63 KKDYYQGNNSDVVATDSQKNTVYLLAKKHGIE-SPEMFALLLAKHFLNKYSHVEEAHVHV 121
Query: 370 EQKPWTRVQQ 399
E PW RV Q
Sbjct: 122 EAYPWQRVCQ 131
[186][TOP]
>UniRef100_B4JEU7 Uricase n=1 Tax=Drosophila grimshawi RepID=B4JEU7_DROGR
Length = 324
Score = 80.9 bits (198), Expect = 5e-14
Identities = 53/178 (29%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +1
Query: 4 SALSHIKPLPTRASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDS 183
S L + L + S + Y + +GK V++ V R G VH + E V T +
Sbjct: 4 SPLQNYTKLNAPTAFSHEQQSPYEIVSKSYGKDAVKVLHVNRRGPVHTIQELEVGTHLKL 63
Query: 184 DMEHAFLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKI 363
+ ++ G N+ + ATD+QKNTVY++A++ + + E++A+ + HF+ Y V +A +
Sbjct: 64 NSNKDYVLGVNSDVVATDSQKNTVYLLAKKYGVE-SPEKFALIVGNHFLSKYAHVEEAHV 122
Query: 364 YVEQKPWTRV---QQSGLPHDHGFALQGT-EVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+VE PW R+ Q PH+H F T E + +A V +G++ L +LK
Sbjct: 123 HVEAYPWQRIHQKNQQSQPHNHAFLFSPTAEHYCDVIVRRQAPKQTVISGIRGLRVLK 180
[187][TOP]
>UniRef100_B3MJN3 Uricase n=1 Tax=Drosophila ananassae RepID=B3MJN3_DROAN
Length = 351
Score = 80.9 bits (198), Expect = 5e-14
Identities = 43/110 (39%), Positives = 68/110 (61%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 31 YEITDHGYGKDAVKVLHVSRKGPVHTIQEYEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 90
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++AI LAQHF+ Y V +A ++VE PW RV Q
Sbjct: 91 TVYLLAKKHGVE-SPEKFAILLAQHFLNKYSHVEEAHVHVEAYPWQRVCQ 139
[188][TOP]
>UniRef100_A3LMZ3 Uricase n=1 Tax=Pichia stipitis RepID=A3LMZ3_PICST
Length = 304
Score = 80.9 bits (198), Expect = 5e-14
Identities = 49/150 (32%), Positives = 82/150 (54%), Gaps = 5/150 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK+ V+ +V ++ + ++E NV ++ D + A+ DN + TDT KNT+ V
Sbjct: 9 YGKANVKFLKVKKNPSNPDEQEVLEANVQCLLKGDFDIAYTKADNAPIVPTDTVKNTILV 68
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS-GLPHDHGFALQG 438
A+ + IE++A LA+HF Y V +I + Q W++ S G H H F G
Sbjct: 69 EAKN-TDVWPIERFAAHLAKHFTGKYSQVHSVEITIVQSRWSKFPLSNGKVHPHSFRYDG 127
Query: 439 TEVRTVYVTYDK-AGTLDVTAGLKDLSLLK 525
E + ++TYDK + L +T+ +KDL++LK
Sbjct: 128 PETKRTFLTYDKFSKKLTLTSAIKDLTVLK 157
[189][TOP]
>UniRef100_A1C6A2 Uricase n=1 Tax=Aspergillus clavatus RepID=A1C6A2_ASPCL
Length = 300
Score = 80.9 bits (198), Expect = 5e-14
Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V +VE V +++ ++E ++ DN+ + ATD+ KNT+Y+
Sbjct: 8 YGKDNVRVYKVHRDEKTGVQTVVEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYIT 67
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E + L HF++ Y + A + + W+R+ G PH H F E
Sbjct: 68 AKQ-NPVTPPELFGSILGSHFIQKYKHIHAAHVNIVTHRWSRMNIDGKPHPHSFVRDSEE 126
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +D+ + + L++LK
Sbjct: 127 TRNVQVDVARTTGIDIRSSISKLTVLK 153
[190][TOP]
>UniRef100_A2SXR1 Uricase n=1 Tax=Phytophthora parasitica RepID=A2SXR1_PHYPR
Length = 307
Score = 80.5 bits (197), Expect = 7e-14
Identities = 51/158 (32%), Positives = 85/158 (53%), Gaps = 11/158 (6%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMID-SDMEHAFLNGDNTGMTATDTQKNTVYV 261
H HGK +VR+ +V R H +++ +++ + A+ +GDN + TD+ KNTV+V
Sbjct: 8 HEHGKGRVRMLKVTRTPEKHSVIQLEAEVLLEGAPAASAYYDGDNGRVLPTDSVKNTVWV 67
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYP-LVSKAKIYVEQKPWTRV-----QQSGLPHDHG 423
+A++ + ++E + + LA+HFV +P ++S AK+ + + PW RV + PH H
Sbjct: 68 LAKK-HEFASLEDFGVILAKHFVTKHPDIISVAKVKLFETPWQRVVVPDSKGKTRPHHHA 126
Query: 424 FALQGTEVRTVYVTYDKA--GTLDVT--AGLKDLSLLK 525
F T YV K+ G DVT G+ L +LK
Sbjct: 127 FVSASPGFSTAYVVARKSAYGAPDVTVQGGVDGLKVLK 164
[191][TOP]
>UniRef100_P16163 Uricase n=2 Tax=Drosophila melanogaster RepID=URIC_DROME
Length = 352
Score = 80.5 bits (197), Expect = 7e-14
Identities = 44/132 (33%), Positives = 76/132 (57%)
Frame = +1
Query: 4 SALSHIKPLPTRASNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDS 183
+A +H P + + Y + H +GK V++ V R+G VH + E+ V T +
Sbjct: 10 AAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKL 69
Query: 184 DMEHAFLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKI 363
+ + G+N+ + ATD+QKNTVY++A++ + + E++A+ LA+HF+ Y V +A +
Sbjct: 70 YSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIE-SPEKFALLLARHFINKYSHVEEAHV 128
Query: 364 YVEQKPWTRVQQ 399
+VE PW RV Q
Sbjct: 129 HVEAYPWQRVCQ 140
[192][TOP]
>UniRef100_Q9HGJ0 Uricase n=1 Tax=Tolypocladium inflatum RepID=Q9HGJ0_TOLIN
Length = 296
Score = 80.5 bits (197), Expect = 7e-14
Identities = 44/147 (29%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDG--NVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD V H+ E V +++ D++ ++ DN+ + ATD+ KNT++++
Sbjct: 9 YGKDNVRVLKVTRDAATGVQHVTEMTVCCLLEGDIDASYTEADNSVVVATDSIKNTIFIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A L HFV+ Y + A + V W R+ G PH H F E
Sbjct: 69 AKQ-HPVTPPELFAAILGSHFVQKYSHIHVANVTVVTHRWVRMDVDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V + + +T+ + L++LK
Sbjct: 128 TRNVEARVSRKDGIALTSAIAGLTVLK 154
[193][TOP]
>UniRef100_Q4PGU1 Uricase n=1 Tax=Ustilago maydis RepID=Q4PGU1_USTMA
Length = 327
Score = 80.5 bits (197), Expect = 7e-14
Identities = 54/176 (30%), Positives = 97/176 (55%), Gaps = 13/176 (7%)
Frame = +1
Query: 37 RASNSTTNMATYALPLHHHGKSKVRLGRVWRDG---NVHHMVEWNVNTMIDSD-MEHAFL 204
+AS+S +A+ + +GK VR+ R+ RD + H + E+ V ++ + + ++
Sbjct: 4 KASSSNVRLASAS-----YGKDLVRIFRIVRDSKDPSSHRVAEYTVRCLLHGESLTPSYT 58
Query: 205 NGDNTGMTATDTQKNTVYVVAQRMSQKCTI--EQYAIALAQHFVRTYPLVSKAKIYVEQK 378
DN+ + ATDT KNT+ +A+ + + + E+YA+ + HF+ TY + K ++ + Q
Sbjct: 59 EADNSPVVATDTVKNTLNYLAKVLPAEDVLCPERYALNVVNHFLTTYSHIEKTEVDLIQH 118
Query: 379 PWTRV---QQSGLPHDHGFALQGTEVRTVYVTYDKAGT-LDVT---AGLKDLSLLK 525
WTR+ Q+ G H H F G E RTV +++G+ ++VT G+K L +LK
Sbjct: 119 KWTRIVLDQKDGGAHKHSFVRDGEEKRTVRALGERSGSEINVTTLEGGIKGLLVLK 174
[194][TOP]
>UniRef100_B8M8L2 Uricase n=1 Tax=Talaromyces stipitatus ATCC 10500
RepID=B8M8L2_TALSN
Length = 302
Score = 80.5 bits (197), Expect = 7e-14
Identities = 43/147 (29%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD +VE V +++ D++ ++ DN+ + ATD+ KNT++++
Sbjct: 10 YGKDNVRVYKVHRDEKTGFQTVVEMTVCCLLEGDIDVSYTKADNSVVVATDSIKNTIFIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ T E +A + HF++ Y + A + + WTR+ G PH H F G E
Sbjct: 70 AKQ-HPVTTPEVFASIIGNHFIQKYSHIHVAHVNIITHRWTRMTIDGKPHPHSFLRDGAE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +++ + ++ L +LK
Sbjct: 129 TRNVQVDVTEGKGIEIASTIQGLHVLK 155
[195][TOP]
>UniRef100_Q9HGJ3 Uricase n=1 Tax=Geisha distinctissima yeast-like symbiont
RepID=Q9HGJ3_9ASCO
Length = 296
Score = 79.7 bits (195), Expect = 1e-13
Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V R+ V + E + +I+ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 9 YGKDNVRVLKVSRNAGTGVQTVTEMTIRCLIEGDIEASYTGADNSSVVATDSIKNTIYIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ E +A ++ HF++ Y + A + + W R+ G PH H F E
Sbjct: 69 AKQHRVNPP-ELFASIISSHFIQKYSHIHVADVDIVTHRWLRMDVDGKPHPHSFIKDAGE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V+V + + + + + LSLLK
Sbjct: 128 TRNVHVHAKRQDGIAIASSIVGLSLLK 154
[196][TOP]
>UniRef100_Q6CNP7 Uricase n=1 Tax=Kluyveromyces lactis RepID=Q6CNP7_KLULA
Length = 308
Score = 79.7 bits (195), Expect = 1e-13
Identities = 52/162 (32%), Positives = 82/162 (50%), Gaps = 7/162 (4%)
Frame = +1
Query: 61 MATYA-LPLHHHGKSKVRLGRVWR---DGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMT 228
M+TY+ L +GK V+ +V + D VH ++E NV ++ D E ++ DNT +
Sbjct: 1 MSTYSYLADSTYGKDNVKFLKVKKSKTDPKVHEVMECNVQVLLKGDFEVSYTEADNTPIV 60
Query: 229 ATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGL 408
TDT KNT+ V A++ IE++A LA HF Y VS + + Q W +
Sbjct: 61 PTDTVKNTILVHARKF-DTWPIEKFAANLALHFTGKYAHVSGITVKIIQDRWIKYDVDNK 119
Query: 409 PHDHGFALQGTEVRTVYVTYDK---AGTLDVTAGLKDLSLLK 525
H F QG E + ++ YDK + + + +KDL++LK
Sbjct: 120 ESYHSFIHQGPEKKICFLDYDKKNGSSSYTLVTSIKDLTVLK 161
[197][TOP]
>UniRef100_C5E304 Uricase n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5E304_LACTC
Length = 307
Score = 79.7 bits (195), Expect = 1e-13
Identities = 46/151 (30%), Positives = 76/151 (50%), Gaps = 6/151 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D VH ++E V ++ D E ++ DN + TDT KNT+ +
Sbjct: 11 YGKDNVKFLKVKKDKTNPKVHEIMEATVCVLLKGDFEISYTEADNAPIVPTDTVKNTILI 70
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
+A++ IE++A LA HF Y VS + + Q W + G H F QG
Sbjct: 71 LAKKYDT-FPIEKFAAKLALHFTSKYSHVSGLTVKITQDRWVKFDVDGKESQHSFVHQGP 129
Query: 442 EVRTVYVTYDK---AGTLDVTAGLKDLSLLK 525
E + ++ YDK +++ +KDL++LK
Sbjct: 130 EKKITFLDYDKKNGPSNYSLSSSIKDLTVLK 160
[198][TOP]
>UniRef100_C1BS10 Uricase n=1 Tax=Lepeophtheirus salmonis RepID=C1BS10_9MAXI
Length = 313
Score = 79.3 bits (194), Expect = 1e-13
Identities = 50/147 (34%), Positives = 82/147 (55%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GKS V+L V R+ N+H + E+ VNT + + E + G+N + ATD+QKNTVY++A+
Sbjct: 23 YGKSYVKLLHVTRNKNIHTVKEYEVNTFLTLETEDDYTVGNNKHVVATDSQKNTVYLLAK 82
Query: 271 RMSQKCTIEQYAIALAQHFVRTYP-LVSKAKIYVEQK-PWTRVQQSGLPHDHGFALQGTE 444
+ + + E++A+ L +HF+ Y V +A VE+ W R++ H H F+ +
Sbjct: 83 QFGIE-SPEKFALLLVKHFLTKYAGSVIEATAEVEESFKWKRMRGD---HCHAFSADSSL 138
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
RT VT + GLK+ +LK
Sbjct: 139 TRTCKVTQKSGEVPQIFVGLKNFRILK 165
[199][TOP]
>UniRef100_Q7SBV5 Uricase n=1 Tax=Neurospora crassa RepID=Q7SBV5_NEUCR
Length = 295
Score = 79.3 bits (194), Expect = 1e-13
Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V +D + E V +++ +++ ++ DN+ + ATD+ KNT+Y+
Sbjct: 9 YGKDNVRVYKVHKDEKTGQQSVTEMTVCCLLEGEIDTSYTQADNSVIVATDSIKNTIYIK 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A+ E YA L QHF+ Y +S A I V WTR+ G PH H F G E
Sbjct: 69 AKEHPVNPP-ELYASILGQHFLDKYAHISAAHIDVTVHRWTRMVIDGQPHPHSFLRDGQE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V T + G + + +G+ L +LK
Sbjct: 128 TRNVEATVTRDG-ITIKSGIVGLQVLK 153
[200][TOP]
>UniRef100_Q1DZB9 Uricase n=1 Tax=Coccidioides immitis RepID=Q1DZB9_COCIM
Length = 309
Score = 79.3 bits (194), Expect = 1e-13
Identities = 41/147 (27%), Positives = 77/147 (52%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK V++ +V RD + E V+ +++ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKENVKVCKVHRDTTTGWQTVTEMTVSVLLEGDIESSYTKADNSVVVATDSMKNTIYIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E +A + HF+ Y + A +++ WTR+ G H H F GT+
Sbjct: 70 AKQ-HPVTSPELFASIIGSHFIEAYKHIHAAHVHIVAHRWTRMAIDGKLHPHSFMRDGTD 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VR + +++ + + L LLK
Sbjct: 129 VRIADADVIEGKGIEIKSSISGLLLLK 155
[201][TOP]
>UniRef100_B4Q5T2 Uricase n=1 Tax=Drosophila simulans RepID=B4Q5T2_DROSI
Length = 351
Score = 79.0 bits (193), Expect = 2e-13
Identities = 41/110 (37%), Positives = 69/110 (62%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + +G+N+ + ATD+QKN
Sbjct: 31 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYHGNNSDIVATDSQKN 90
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ Y V +A ++VE PW RV Q
Sbjct: 91 TVYLLAKKHGIE-SPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQ 139
[202][TOP]
>UniRef100_O44111 Uricase (Fragment) n=1 Tax=Drosophila subobscura RepID=URIC_DROSU
Length = 339
Score = 79.0 bits (193), Expect = 2e-13
Identities = 46/130 (35%), Positives = 73/130 (56%), Gaps = 7/130 (5%)
Frame = +1
Query: 31 PTRASNSTTNMAT-------YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDM 189
P+ ASN T Y + H +GK V++ V R G VH + E+ V T +
Sbjct: 4 PSSASNRTAASLDGQETPFQYEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYS 63
Query: 190 EHAFLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYV 369
+ + G+N+ + ATD+QKNTVY++A++ + + E++A+ L QHF+ Y V +A ++V
Sbjct: 64 KKDYYQGNNSDIVATDSQKNTVYLLAKKYGIE-SPEKFALLLGQHFLNKYSHVEEAHVHV 122
Query: 370 EQKPWTRVQQ 399
E PW RV Q
Sbjct: 123 ETYPWQRVCQ 132
[203][TOP]
>UniRef100_Q56RC9 Uricase (Fragment) n=1 Tax=Drosophila affinis RepID=Q56RC9_DROAI
Length = 322
Score = 78.6 bits (192), Expect = 3e-13
Identities = 42/110 (38%), Positives = 67/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 26 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 85
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ L QHF+ Y V +A I+VE PW RV Q
Sbjct: 86 TVYLLAKKYGIE-SPEKFALMLGQHFLNKYSHVEEAHIHVETYPWQRVCQ 134
[204][TOP]
>UniRef100_B4NZH1 Uricase n=1 Tax=Drosophila yakuba RepID=B4NZH1_DROYA
Length = 351
Score = 78.6 bits (192), Expect = 3e-13
Identities = 41/110 (37%), Positives = 68/110 (61%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 31 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 90
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ Y V +A ++VE PW RV Q
Sbjct: 91 TVYLLAKKHGIE-SPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQ 139
[205][TOP]
>UniRef100_B4HYA0 Uricase n=1 Tax=Drosophila sechellia RepID=B4HYA0_DROSE
Length = 351
Score = 78.6 bits (192), Expect = 3e-13
Identities = 41/110 (37%), Positives = 68/110 (61%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 31 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 90
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ Y V +A ++VE PW RV Q
Sbjct: 91 TVYLLAKKHGIE-SPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQ 139
[206][TOP]
>UniRef100_B3N6N5 Uricase n=1 Tax=Drosophila erecta RepID=B3N6N5_DROER
Length = 351
Score = 78.6 bits (192), Expect = 3e-13
Identities = 41/110 (37%), Positives = 68/110 (61%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 31 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 90
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ Y V +A ++VE PW RV Q
Sbjct: 91 TVYLLAKKHGIE-SPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQ 139
[207][TOP]
>UniRef100_Q56RC7 Uricase (Fragment) n=2 Tax=Drosophila miranda RepID=Q56RC7_DROMI
Length = 319
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/110 (37%), Positives = 67/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 27 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 86
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ L QHF+ Y V +A ++VE PW RV Q
Sbjct: 87 TVYLLAKKYGIE-SPEKFALMLGQHFLNKYSHVEEAHVHVETYPWQRVCQ 135
[208][TOP]
>UniRef100_B4G8E6 Uricase n=1 Tax=Drosophila persimilis RepID=B4G8E6_DROPE
Length = 346
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/110 (37%), Positives = 67/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 30 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 89
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ L QHF+ Y V +A ++VE PW RV Q
Sbjct: 90 TVYLLAKKYGIE-SPEKFALMLGQHFLNKYSHVEEAHVHVETYPWQRVCQ 138
[209][TOP]
>UniRef100_P22673 Uricase n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=URIC_DROPS
Length = 346
Score = 78.2 bits (191), Expect = 3e-13
Identities = 41/110 (37%), Positives = 67/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 30 YEITDHGYGKDAVKVLHVSRKGPVHTIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKN 89
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ L QHF+ Y V +A ++VE PW RV Q
Sbjct: 90 TVYLLAKKYGIE-SPEKFALMLGQHFLNKYSHVEEAHVHVETYPWQRVCQ 138
[210][TOP]
>UniRef100_Q9FRY4 Uricase (Fragment) n=1 Tax=Astragalus sinicus RepID=Q9FRY4_ASTSI
Length = 205
Score = 77.8 bits (190), Expect = 4e-13
Identities = 38/90 (42%), Positives = 59/90 (65%)
Frame = +1
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
YV A+ S+ ++E +AI LA+HF Y V+ A + + +KPW R+ +G PH+HGF L
Sbjct: 1 YVKAKECSEILSVEDFAIILARHFTSFYNQVTTAIVKIVEKPWERLNVNGQPHEHGFKL- 59
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G+E TV +K+G L +T+G++ LS+LK
Sbjct: 60 GSEKHTVEAIVNKSGALQLTSGIEGLSVLK 89
[211][TOP]
>UniRef100_Q9FEH0 Uricase (Fragment) n=1 Tax=Astragalus sinicus RepID=Q9FEH0_ASTSI
Length = 205
Score = 77.8 bits (190), Expect = 4e-13
Identities = 38/90 (42%), Positives = 59/90 (65%)
Frame = +1
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
YV A+ S+ ++E +AI LA+HF Y V+ A + + +KPW R+ +G PH+HGF L
Sbjct: 1 YVKAKECSEILSVEDFAIILARHFTSFYNQVTTAIVKIVEKPWERLNVNGQPHEHGFKL- 59
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G+E TV +K+G L +T+G++ LS+LK
Sbjct: 60 GSEKHTVEAIVNKSGALQLTSGIEGLSVLK 89
[212][TOP]
>UniRef100_B6QP94 Uricase n=1 Tax=Penicillium marneffei ATCC 18224 RepID=B6QP94_PENMQ
Length = 302
Score = 77.8 bits (190), Expect = 4e-13
Identities = 42/147 (28%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V RD +VE V +++ D++ ++ DN+ + ATD+ KNT++++
Sbjct: 10 YGKDNVRVYKVHRDEKTGFQTVVEMTVCCLLEGDIDVSYTKADNSVVVATDSIKNTIFIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ T E + + HF+ Y + A + + WTR+ G PH H F G E
Sbjct: 70 AKQ-HPVTTPEVFGSIIGSHFIEKYSHIHAAHVNIITHRWTRMTIDGKPHPHSFLRDGAE 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + + + + ++ L +LK
Sbjct: 129 TRNVQVDVTEGKGIKIASTIQGLHVLK 155
[213][TOP]
>UniRef100_Q8C7K4 Uricase (Fragment) n=1 Tax=Mus musculus RepID=Q8C7K4_MOUSE
Length = 251
Score = 77.4 bits (189), Expect = 6e-13
Identities = 39/109 (35%), Positives = 67/109 (61%)
Frame = +1
Query: 199 FLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQK 378
+L+GDN+ + TDT KNTV+V+A+ + IE +A+ + +HF+ ++ V++A +YVE+
Sbjct: 5 YLHGDNSDIIPTDTIKNTVHVLAKLRGIR-NIETFAMNICEHFLSSFNHVTRAHVYVEEV 63
Query: 379 PWTRVQQSGLPHDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
PW R +++G+ H H F T V + G + +G+KDL +LK
Sbjct: 64 PWKRFEKNGIKHVHAFIHTPTGTHFCEVEQMRNGPPVIHSGIKDLKVLK 112
[214][TOP]
>UniRef100_A2QG92 Uricase n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2QG92_ASPNC
Length = 306
Score = 77.4 bits (189), Expect = 6e-13
Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 2/154 (1%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQ 243
Y L +GK VRL +V RD V + E V +++ D+E ++ DN+ + TD
Sbjct: 2 YNLSDAQYGKDNVRLYKVHRDAGTGVQTVYELTVCVLLEGDIETSYTKEDNSVLVTTDAI 61
Query: 244 KNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHG 423
KNT Y+VA+ + E + L +HF+ Y + A I + W R+ PH H
Sbjct: 62 KNTCYIVAKH-NPVHPPELFGSILGKHFITQYKHIHTAHIDITCHTWERMTIENEPHPHS 120
Query: 424 FALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
F G+ R + V KA +++T+ + LS+LK
Sbjct: 121 FYQDGSVKRQIRVDVSKASGINITSAIFGLSVLK 154
[215][TOP]
>UniRef100_B4N0V0 Uricase n=1 Tax=Drosophila willistoni RepID=B4N0V0_DROWI
Length = 352
Score = 77.0 bits (188), Expect = 7e-13
Identities = 41/110 (37%), Positives = 67/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + H +GK V++ V R G VH + E+ V T + + + G+N+ + ATD+QKN
Sbjct: 29 YEITDHGYGKDAVKVLHVSRKGPVHTIHEFEVGTHLKLYSKKDYYQGNNSDVVATDSQKN 88
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E +A+ LA+HF+ Y V +A ++VE PW RV Q
Sbjct: 89 TVYLLAKKHGIE-SPEMFALLLAKHFLNKYSHVEEAHVHVEAYPWQRVCQ 137
[216][TOP]
>UniRef100_C5E037 Uricase n=1 Tax=Zygosaccharomyces rouxii CBS 732 RepID=C5E037_ZYGRC
Length = 305
Score = 77.0 bits (188), Expect = 7e-13
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 6/151 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN---VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYV 261
+GK V+ +V +D + + ++E V ++ + + ++ DN+ + TDT KNT+ +
Sbjct: 9 YGKDNVKFLKVKKDASNPKLQQIMEATVKVLLKGNFDVSYTEADNSPIVPTDTVKNTILI 68
Query: 262 VAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGT 441
+A + + E++A LA HF Y VS I + Q+ W + G P H F QG
Sbjct: 69 LA-KTNDTWPSEKFASTLALHFTTKYAHVSGVSIQIYQERWVKFNVDGAPSQHSFVHQGP 127
Query: 442 EVRTVYVTYDKA---GTLDVTAGLKDLSLLK 525
E + V + YDK ++ +KDL++LK
Sbjct: 128 EKKIVELDYDKVPGPAQYKLSTSIKDLTVLK 158
[217][TOP]
>UniRef100_B1M7C7 Uricase n=1 Tax=Methylobacterium radiotolerans JCM 2831
RepID=B1M7C7_METRJ
Length = 280
Score = 76.6 bits (187), Expect = 1e-12
Identities = 48/151 (31%), Positives = 76/151 (50%)
Frame = +1
Query: 73 ALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNT 252
AL +GK +VR+ R+ RDG+ H E ++ M+ E A+ GDN ATD+ +N
Sbjct: 2 ALTASRYGKERVRVLRLARDGDHHTPREVTLSVMLTGRFEAAWTGGDNRASIATDSIRNI 61
Query: 253 VYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFAL 432
V V A R + E + +A+A+ + TYP V I E+ W R + PH H F
Sbjct: 62 VNVTAAR-NLALDAEGFVVAVARVLLETYPQVETVAIEAEEVRWLRHAIADAPHGHTFTR 120
Query: 433 QGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G +T D++G+ + +GL+ + +K
Sbjct: 121 DGNGAGFAGLTADRSGS-TLRSGLRGYTFMK 150
[218][TOP]
>UniRef100_Q9FRY5 Uricase (Fragment) n=1 Tax=Pisum sativum RepID=Q9FRY5_PEA
Length = 205
Score = 76.6 bits (187), Expect = 1e-12
Identities = 38/90 (42%), Positives = 55/90 (61%)
Frame = +1
Query: 256 YVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQ 435
Y A+ S+ T+E +AI LA+HF Y V+ A + + +KPW RV G PH+HGF L
Sbjct: 1 YAKAKECSEILTVEDFAILLAKHFTSFYKQVTTAIVKIVEKPWERVSVDGQPHEHGFKL- 59
Query: 436 GTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
G+E T K+G L +T+G++ LS+LK
Sbjct: 60 GSEKHTTEAIVKKSGALQLTSGIEGLSVLK 89
[219][TOP]
>UniRef100_C1BR88 Uricase n=1 Tax=Caligus rogercresseyi RepID=C1BR88_9MAXI
Length = 300
Score = 76.6 bits (187), Expect = 1e-12
Identities = 54/149 (36%), Positives = 83/149 (55%), Gaps = 4/149 (2%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GKS V+L V R G++H E+ VNT + E ++ G+N + ATD+QKNTVY++A+
Sbjct: 13 YGKSFVKLFHVERRGDIHTAREYEVNTFLTLAREIDYIEGNNEDVIATDSQKNTVYLLAK 72
Query: 271 RMSQKCTIEQYAIALAQHFVRTYP-LVSKAKIYVEQ-KPWTRVQQSGLPHDHGFALQGTE 444
+ + + E +A + HF++ YP V KA VE+ W R+Q S H H F +
Sbjct: 73 QHGVE-SPESFASVIVSHFLKKYPGNVVKATAEVEECVVWKRMQGS---HAHAFNADTSA 128
Query: 445 VRTVYVTYDKAGTLD--VTAGLKDLSLLK 525
+ VT AG D ++ GLK+ +LK
Sbjct: 129 IHFCKVT-QSAGEKDQQISGGLKNYRILK 156
[220][TOP]
>UniRef100_Q00511 Uricase n=4 Tax=Aspergillus RepID=URIC_ASPFL
Length = 302
Score = 76.6 bits (187), Expect = 1e-12
Identities = 44/153 (28%), Positives = 77/153 (50%), Gaps = 2/153 (1%)
Frame = +1
Query: 73 ALPLHHHGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQK 246
A+ +GK VR+ +V +D V + E V +++ ++E ++ DN+ + ATD+ K
Sbjct: 3 AVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIK 62
Query: 247 NTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGF 426
NT+Y+ A++ + E + L HF+ Y + A + + WTR+ G PH H F
Sbjct: 63 NTIYITAKQ-NPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSF 121
Query: 427 ALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
E R V V + +D+ + L L++LK
Sbjct: 122 IRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLK 154
[221][TOP]
>UniRef100_Q9RV70 Uricase n=1 Tax=Deinococcus radiodurans RepID=Q9RV70_DEIRA
Length = 298
Score = 75.5 bits (184), Expect = 2e-12
Identities = 50/149 (33%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 85 HHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+++GK++V+L ++ R H + E V + D A GDNT + ATDT +NTVY +
Sbjct: 21 NNYGKAEVQLMKIKRGTPRHELREAKVRVAMYGDFGAAHSEGDNTDLVATDTVRNTVYGL 80
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP--HDHGFALQG 438
A+ + +IE++ L HFV+ P V+ + W RVQ P HDH F Q
Sbjct: 81 AKE-GFESSIEEFGKELLTHFVKVGPRVTGGFAEFTEHLWERVQTPAQPQGHDHAFVRQM 139
Query: 439 TEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+ RT V VT+G+++L +LK
Sbjct: 140 PK-RTARVETQDGRRFTVTSGIEELYVLK 167
[222][TOP]
>UniRef100_C5P059 Uricase n=1 Tax=Coccidioides posadasii C735 delta SOWgp
RepID=C5P059_COCP7
Length = 309
Score = 75.5 bits (184), Expect = 2e-12
Identities = 40/147 (27%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNV--HHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK V++ +V RD + E V+ +++ D+E ++ DN+ + ATD+ KNT+Y++
Sbjct: 10 YGKENVKVCKVHRDTTTGWQTVTEMTVSVLLEGDIESSYTKADNSVVVATDSMKNTIYIL 69
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E +A + HF+ Y + A + + WTR+ G H H F G +
Sbjct: 70 AKQ-HPVTSPELFASIIGSHFIEAYKHIHAAHVNIVAHRWTRMAIDGKLHPHSFMRDGMD 128
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
VR + +++ + + L LLK
Sbjct: 129 VRIADADVIEGKGIEIKSSISGLLLLK 155
[223][TOP]
>UniRef100_C7M9Y5 Urate oxidase n=1 Tax=Brachybacterium faecium DSM 4810
RepID=C7M9Y5_BRAFD
Length = 314
Score = 74.3 bits (181), Expect = 5e-12
Identities = 55/169 (32%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = +1
Query: 22 KPLPTRA-SNSTTNMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHA 198
KP R+ S S N A L +GK++ + R+ R H + + V + + D+E
Sbjct: 7 KPSTHRSDSASPPNEAEIVLGPTQYGKAETHVVRITRGTPRHEIRDVTVTSQLRGDLEAM 66
Query: 199 FLNGDNTGMTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQK 378
GDN ATDTQKNTV+ AQ K + EQ +AL+ HF + + + E+
Sbjct: 67 HSEGDNAHCVATDTQKNTVFGFAQTHGVK-SPEQLLLALSDHFTSEFEWIHGGRWEAEEH 125
Query: 379 PWTRVQQSGLPHDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
W R+ HDH F E RT V D V +G DL++LK
Sbjct: 126 AWERIDD----HDHCFVESKQEKRTAVVVTD-GEKRTVISGFYDLTVLK 169
[224][TOP]
>UniRef100_P33282 Uricase n=2 Tax=Emericella nidulans RepID=URIC_EMENI
Length = 301
Score = 74.3 bits (181), Expect = 5e-12
Identities = 40/147 (27%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGN--VHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 264
+GK VR+ +V +D V + E V +++ +++ ++ DN+ + ATD+ KNT++++
Sbjct: 9 YGKDNVRVYKVHKDPKTGVQTVTEMTVCVLLEGEIDTSYTKADNSVIVATDSIKNTIFIL 68
Query: 265 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 444
A++ + E + L HF+ Y + A + WTR+ G PH H F E
Sbjct: 69 AKQ-NPVTPPELFGSILGTHFINKYKHIHVAHTNIITHRWTRLNIDGKPHSHSFVRDSEE 127
Query: 445 VRTVYVTYDKAGTLDVTAGLKDLSLLK 525
R V V + +D+ + + L++LK
Sbjct: 128 TRNVQVDVTEGVGIDIKSSINKLTVLK 154
[225][TOP]
>UniRef100_B0DDT7 Uricase n=1 Tax=Laccaria bicolor S238N-H82 RepID=B0DDT7_LACBS
Length = 317
Score = 73.9 bits (180), Expect = 6e-12
Identities = 50/165 (30%), Positives = 82/165 (49%), Gaps = 9/165 (5%)
Frame = +1
Query: 58 NMATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATD 237
N +L +GK+KVR+ R+ R HH+VE+NV +++ D+E ++ DN+ +
Sbjct: 3 NKPLSSLTAARYGKAKVRVFRIVRQDKWHHIVEYNVEALLEGDLESSYTEADNSVVRVFT 62
Query: 238 TQKNTVYVVAQRMSQK-CTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTR--VQQSGL 408
+ + ++S E++A+ L FV Y + KA + +EQ W R V++ L
Sbjct: 63 SLIRVIRRYLAKISPYILNPEKFALHLGTFFVSKYAHIHKAFVTIEQLRWARIPVEKGNL 122
Query: 409 -PHDHGFALQGTEVRTVYVTYDKAGTLD-----VTAGLKDLSLLK 525
H H F G + R V V D + D V+AG+ DL +LK
Sbjct: 123 KEHPHAFYRDGDDKRVVKVEVDASKGKDKLVGRVSAGISDLLVLK 167
[226][TOP]
>UniRef100_B4M6K8 Uricase n=1 Tax=Drosophila virilis RepID=B4M6K8_DROVI
Length = 342
Score = 73.2 bits (178), Expect = 1e-11
Identities = 38/110 (34%), Positives = 66/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + +GK V++ + R G VH + E V T + ++ G+N+ + ATD+QKN
Sbjct: 26 YEITNKGYGKDAVKVMHINRKGPVHSIQELEVGTHLKLYSNKDYMLGNNSDVVATDSQKN 85
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ TY V + ++VE PW R+ Q
Sbjct: 86 TVYLLAKKHGIE-SPEKFALILAKHFLSTYAHVEEVHVHVEAYPWQRMTQ 134
[227][TOP]
>UniRef100_P23194 Uricase n=1 Tax=Drosophila virilis RepID=URIC_DROVI
Length = 342
Score = 73.2 bits (178), Expect = 1e-11
Identities = 38/110 (34%), Positives = 66/110 (60%)
Frame = +1
Query: 70 YALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKN 249
Y + +GK V++ + R G VH + E V T + ++ G+N+ + ATD+QKN
Sbjct: 26 YEITNKGYGKDAVKVMHINRKGPVHSIQELEVGTHLKLYSNKDYMLGNNSDVVATDSQKN 85
Query: 250 TVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQ 399
TVY++A++ + + E++A+ LA+HF+ TY V + ++VE PW R+ Q
Sbjct: 86 TVYLLAKKHGIE-SPEKFALILAKHFLSTYAHVEEVHVHVEAYPWQRMTQ 134
[228][TOP]
>UniRef100_B2GGK9 Uricase n=1 Tax=Kocuria rhizophila DC2201 RepID=B2GGK9_KOCRD
Length = 294
Score = 71.2 bits (173), Expect = 4e-11
Identities = 47/155 (30%), Positives = 74/155 (47%)
Frame = +1
Query: 61 MATYALPLHHHGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDT 240
M L + +GK++ + R+ RD + H + + V + + D E GDN TDT
Sbjct: 1 MTDVVLGKNQYGKAENHVVRIHRDTDRHVIRDLVVTSQLRGDFEAVHTQGDNAHCVPTDT 60
Query: 241 QKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDH 420
QKNTV+ Q+ + E + L++HF + VS + ++ W R+ +DH
Sbjct: 61 QKNTVFAFVQKYGVD-SPEALLLKLSEHFTSEFEWVSGGRWAADEHAWDRIND----NDH 115
Query: 421 GFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
F EVRT V D + V +G KDL++LK
Sbjct: 116 CFVQNKQEVRTAVVVTDGPRS-TVISGFKDLTVLK 149
[229][TOP]
>UniRef100_Q3S560 Uricase (Fragment) n=1 Tax=Hippoglossus hippoglossus
RepID=Q3S560_HIPHI
Length = 202
Score = 70.5 bits (171), Expect = 7e-11
Identities = 36/98 (36%), Positives = 62/98 (63%)
Frame = +1
Query: 232 TDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLP 411
TDT KNTV+ +A+ K TIEQ+++ + HF+ ++ V +AK+Y+E+ PW R++++G+
Sbjct: 2 TDTIKNTVHALAKIKGVK-TIEQFSLDICNHFLTSFNHVLRAKVYMEEAPWRRLEKNGVE 60
Query: 412 HDHGFALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
H H F L R V + G V +G+K++++LK
Sbjct: 61 HAHAFILCPEACRFCDVEQNLNGVPVVHSGVKNMTVLK 98
[230][TOP]
>UniRef100_B4JEU8 Uricase n=1 Tax=Drosophila grimshawi RepID=B4JEU8_DROGR
Length = 327
Score = 69.7 bits (169), Expect = 1e-10
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 11/156 (7%)
Frame = +1
Query: 91 HGKSKVRLGRVWRDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVVAQ 270
+GK V+L V R+G VH + E V T + ++ G N+ + +D KN VY++A+
Sbjct: 33 YGKDAVKLLHVDRNGPVHTIQELEVGTHLKLTTNKEYVLGINSDVVDSDAMKNVVYLLAK 92
Query: 271 RMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQ----------QSGLPHDH 420
+ + E++A+ + HF+ TY V +A + VE PW R++ Q PH+H
Sbjct: 93 KYGIEGP-EKFALLVGNHFLATYAHVYEAHVRVEAYPWQRIRQGDSEDTGKGQQSQPHNH 151
Query: 421 GFALQGTEVRTVYVTYDKAGTLD-VTAGLKDLSLLK 525
F T V + + V +G+K L +LK
Sbjct: 152 AFVFAPTAVHFCDIIVRRNDPKQTVISGIKKLRVLK 187
[231][TOP]
>UniRef100_B4FFW7 Uricase n=1 Tax=Zea mays RepID=B4FFW7_MAIZE
Length = 227
Score = 68.6 bits (166), Expect = 3e-10
Identities = 31/78 (39%), Positives = 49/78 (62%)
Frame = +1
Query: 292 IEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVRTVYVTYD 471
+E++A+ L +HF YP VS+A + + ++PW RV G PH HGF + G E + V
Sbjct: 1 MEEFAVILGRHFTSLYPQVSEATVTIVERPWERVTVDGKPHSHGFKV-GVEKHSTEVIVK 59
Query: 472 KAGTLDVTAGLKDLSLLK 525
K+G+L + +G++ SLLK
Sbjct: 60 KSGSLRINSGIQGYSLLK 77
[232][TOP]
>UniRef100_B4XP49 Uricase (Fragment) n=1 Tax=Taeniopygia guttata RepID=B4XP49_TAEGU
Length = 235
Score = 64.7 bits (156), Expect = 4e-09
Identities = 33/93 (35%), Positives = 53/93 (56%)
Frame = +1
Query: 247 NTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGF 426
N V V+A++ ++EQ+AI + HF+ T+ V+ K Y+++ PW R+ + G+PH H F
Sbjct: 1 NIVLVLAKKNGIS-SLEQFAIDICNHFMTTFCQVAYVKTYIQEVPWQRLHEDGVPHIHSF 59
Query: 427 ALQGTEVRTVYVTYDKAGTLDVTAGLKDLSLLK 525
+R + G L V AG+KDL L+K
Sbjct: 60 ICVPDGIRFCEAEQCRNGPLIVFAGIKDLKLMK 92
[233][TOP]
>UniRef100_B7G802 Uricase (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7G802_PHATR
Length = 247
Score = 59.7 bits (143), Expect = 1e-07
Identities = 29/86 (33%), Positives = 48/86 (55%)
Frame = +1
Query: 223 MTATDTQKNTVYVVAQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQS 402
+ ATDTQKN+VYVVA++ ++ + E++ + L++ + YP + + V++ W R
Sbjct: 2 IVATDTQKNSVYVVAKQ-NEFHSPEEFGVLLSRFLLTQYPWLEAVDVVVDESTWQRAVVD 60
Query: 403 GLPHDHGFALQGTEVRTVYVTYDKAG 480
G PH HGF G E + V + G
Sbjct: 61 GQPHPHGFVKSGPEAQHAAVHMARTG 86
[234][TOP]
>UniRef100_UPI000154862E UPI000154862E related cluster n=1 Tax=Mus musculus
RepID=UPI000154862E
Length = 199
Score = 56.6 bits (135), Expect = 1e-06
Identities = 26/78 (33%), Positives = 46/78 (58%)
Frame = +1
Query: 292 IEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTEVRTVYVTYD 471
IE +A+ + +HF+ ++ V++A +YVE+ PW R +++G+ H H F T V
Sbjct: 14 IETFAMNICEHFLSSFNHVTRAHVYVEEVPWKRFEKNGIKHVHAFIHTPTGTHFCEVEQM 73
Query: 472 KAGTLDVTAGLKDLSLLK 525
+ G + +G+KDL +LK
Sbjct: 74 RNGPPVIHSGIKDLKVLK 91
[235][TOP]
>UniRef100_Q9ZWU0 Uricase (Fragment) n=1 Tax=Glycine max RepID=Q9ZWU0_SOYBN
Length = 70
Score = 54.7 bits (130), Expect = 4e-06
Identities = 27/56 (48%), Positives = 36/56 (64%), Gaps = 2/56 (3%)
Frame = +1
Query: 91 HGKSKVRLGRVW--RDGNVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNT 252
HGK +VR+ RVW R G H +VEW V + SD +++L DN+ + ATDT KNT
Sbjct: 16 HGKERVRVARVWKTRQGQ-HFIVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNT 70