[UP]

[1][TOP]
>UniRef100_A8IJL3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Chlamydomonas reinhardtii RepID=A8IJL3_CHLRE
          Length = 207

 Score =  338 bits (868), Expect = 1e-91
 Identities = 167/167 (100%), Positives = 167/167 (100%)
 Frame = +2

Query: 2   SLRGRSAFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYK 181
           SLRGRSAFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYK
Sbjct: 5   SLRGRSAFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYK 64

Query: 182 LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFL 361
           LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFL
Sbjct: 65  LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFL 124

Query: 362 KEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           KEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP
Sbjct: 125 KEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 171

[2][TOP]
>UniRef100_A8CF47 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Brassica rapa RepID=A8CF47_BRACM
          Length = 230

 Score =  219 bits (557), Expect = 1e-55
 Identities = 105/143 (73%), Positives = 119/143 (83%), Gaps = 2/143 (1%)
 Frame = +2

Query: 80  AASVVASATAVKAP--SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLL 253
           A+S V     VK P  +LP+RVGHGFDLHRL  GY LIIGGIDIPH +GCEAHSDGDVLL
Sbjct: 55  ASSAVDVTEPVKKPVRTLPFRVGHGFDLHRLEPGYPLIIGGIDIPHDRGCEAHSDGDVLL 114

Query: 254 HTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQ 433
           H V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLMDE GY +GNLD T+I Q
Sbjct: 115 HCVVDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNLDATLILQ 174

Query: 434 KPKLSPHKENIRNNLSAILGADP 502
           +PK+SPHKE IR+NLS +LGADP
Sbjct: 175 RPKISPHKETIRSNLSKLLGADP 197

[3][TOP]
>UniRef100_B9GWV6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Populus trichocarpa RepID=B9GWV6_POPTR
          Length = 233

 Score =  217 bits (552), Expect = 4e-55
 Identities = 105/142 (73%), Positives = 118/142 (83%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAPS-LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V  SAT+ KA   LP+RVGHGFDLHRL  GY LIIGGID+PH +GCEAHSDGDVLLH
Sbjct: 59  ATQVEGSATSSKASRILPFRVGHGFDLHRLEPGYPLIIGGIDVPHDRGCEAHSDGDVLLH 118

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 119 CVVDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMHEAGYEIGNLDATLILQR 178

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE+IR NLS +LGADP
Sbjct: 179 PKLSPHKESIRANLSELLGADP 200

[4][TOP]
>UniRef100_B3GEM4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Fragment)
           n=1 Tax=Populus trichocarpa RepID=B3GEM4_POPTR
          Length = 180

 Score =  216 bits (551), Expect = 5e-55
 Identities = 105/142 (73%), Positives = 118/142 (83%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAPS-LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V  SAT+ KA   LP+RVGHGFDLHRL  GY LIIGGID+PH +GCEAHSDGDVLLH
Sbjct: 6   ATQVEGSATSSKASRILPFRVGHGFDLHRLEPGYPLIIGGIDVPHDRGCEAHSDGDVLLH 65

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 66  CVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYEIGNLDATLILQR 125

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE+IR NLS +LGADP
Sbjct: 126 PKLSPHKESIRANLSELLGADP 147

[5][TOP]
>UniRef100_A9PB62 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Populus trichocarpa RepID=A9PB62_POPTR
          Length = 233

 Score =  216 bits (551), Expect = 5e-55
 Identities = 105/142 (73%), Positives = 118/142 (83%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAPS-LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V  SAT+ KA   LP+RVGHGFDLHRL  GY LIIGGID+PH +GCEAHSDGDVLLH
Sbjct: 59  ATQVEGSATSSKASRILPFRVGHGFDLHRLEPGYPLIIGGIDVPHDRGCEAHSDGDVLLH 118

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 119 CVADAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYEIGNLDATLILQR 178

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE+IR NLS +LGADP
Sbjct: 179 PKLSPHKESIRANLSELLGADP 200

[6][TOP]
>UniRef100_UPI0001982AA5 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
           RepID=UPI0001982AA5
          Length = 231

 Score =  215 bits (547), Expect = 2e-54
 Identities = 109/158 (68%), Positives = 124/158 (78%), Gaps = 11/158 (6%)
 Frame = +2

Query: 62  VQRTCRAASVVASAT-AVKAP----------SLPYRVGHGFDLHRLAEGYKLIIGGIDIP 208
           ++ T R   V A+AT AV+A           SLP+RVGHGFDLHRL  GY LIIGGIDIP
Sbjct: 41  LRSTLRRPMVAAAATTAVEAEPRSNSTAPSKSLPFRVGHGFDLHRLEPGYPLIIGGIDIP 100

Query: 209 HTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDE 388
           H +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E
Sbjct: 101 HDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHE 160

Query: 389 KGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
            GY +GNLD T+I Q+PKLSPHKE IR+NLS +LGADP
Sbjct: 161 AGYEIGNLDATLILQRPKLSPHKEAIRSNLSQLLGADP 198

[7][TOP]
>UniRef100_Q6EPN6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Oryza
           sativa Japonica Group RepID=Q6EPN6_ORYSJ
          Length = 222

 Score =  215 bits (547), Expect = 2e-54
 Identities = 109/170 (64%), Positives = 126/170 (74%), Gaps = 5/170 (2%)
 Frame = +2

Query: 8   RGRSAFSSGRAAPKAFARVQRTCRAASVVAS-----ATAVKAPSLPYRVGHGFDLHRLAE 172
           R RS  S+  A P    R   T  AA+V A      A A K P+LP+RVGHGFDLHRL  
Sbjct: 20  RARSTPSASPARPSLRLRRPSTLAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEP 79

Query: 173 GYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSD 352
           G  LIIGGIDIPH +GC+AHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S 
Sbjct: 80  GLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSS 139

Query: 353 IFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           +F++EAV+LM E GY LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 140 VFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 189

[8][TOP]
>UniRef100_Q0DYN3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Oryza
           sativa Japonica Group RepID=Q0DYN3_ORYSJ
          Length = 275

 Score =  215 bits (547), Expect = 2e-54
 Identities = 109/170 (64%), Positives = 126/170 (74%), Gaps = 5/170 (2%)
 Frame = +2

Query: 8   RGRSAFSSGRAAPKAFARVQRTCRAASVVAS-----ATAVKAPSLPYRVGHGFDLHRLAE 172
           R RS  S+  A P    R   T  AA+V A      A A K P+LP+RVGHGFDLHRL  
Sbjct: 73  RARSTPSASPARPSLRLRRPSTLAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEP 132

Query: 173 GYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSD 352
           G  LIIGGIDIPH +GC+AHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S 
Sbjct: 133 GLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSS 192

Query: 353 IFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           +F++EAV+LM E GY LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 193 VFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 242

[9][TOP]
>UniRef100_A2X8B7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Oryza
           sativa Indica Group RepID=A2X8B7_ORYSI
          Length = 222

 Score =  215 bits (547), Expect = 2e-54
 Identities = 109/170 (64%), Positives = 126/170 (74%), Gaps = 5/170 (2%)
 Frame = +2

Query: 8   RGRSAFSSGRAAPKAFARVQRTCRAASVVAS-----ATAVKAPSLPYRVGHGFDLHRLAE 172
           R RS  S+  A P    R   T  AA+V A      A A K P+LP+RVGHGFDLHRL  
Sbjct: 20  RARSTPSASPARPSLRLRRPSTLAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEP 79

Query: 173 GYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSD 352
           G  LIIGGIDIPH +GC+AHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S 
Sbjct: 80  GLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSS 139

Query: 353 IFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           +F++EAV+LM E GY LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 140 VFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 189

[10][TOP]
>UniRef100_A3AA47 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Oryza
           sativa Japonica Group RepID=A3AA47_ORYSJ
          Length = 222

 Score =  214 bits (546), Expect = 2e-54
 Identities = 109/170 (64%), Positives = 126/170 (74%), Gaps = 5/170 (2%)
 Frame = +2

Query: 8   RGRSAFSSGRAAPKAFARVQRTCRAASVVAS-----ATAVKAPSLPYRVGHGFDLHRLAE 172
           R RS  S+  A P    R   T  AA+V A      A A K P+LP+RVGHGFDLHRL  
Sbjct: 20  RARSTPSASPARPSLRLRRPSTFAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEP 79

Query: 173 GYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSD 352
           G  LIIGGIDIPH +GC+AHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S 
Sbjct: 80  GLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSS 139

Query: 353 IFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           +F++EAV+LM E GY LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 140 VFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 189

[11][TOP]
>UniRef100_Q9CAK8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,
           chloroplastic n=1 Tax=Arabidopsis thaliana
           RepID=ISPF_ARATH
          Length = 231

 Score =  214 bits (546), Expect = 2e-54
 Identities = 104/150 (69%), Positives = 119/150 (79%), Gaps = 1/150 (0%)
 Frame = +2

Query: 56  ARVQRTCRAASVVASATAVK-APSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAH 232
           A V     A  V  S T+ K   +LP+R+GHGFDLHRL  GY LIIGGI IPH +GCEAH
Sbjct: 49  ASVSAASSAVDVNESVTSEKPTKTLPFRIGHGFDLHRLEPGYPLIIGGIVIPHDRGCEAH 108

Query: 233 SDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNL 412
           SDGDVLLH V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLMDE GY +GNL
Sbjct: 109 SDGDVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNL 168

Query: 413 DCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           D T+I Q+PK+SPHKE IR+NLS +LGADP
Sbjct: 169 DATLILQRPKISPHKETIRSNLSKLLGADP 198

[12][TOP]
>UniRef100_A7QNI4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Vitis
           vinifera RepID=A7QNI4_VITVI
          Length = 183

 Score =  214 bits (545), Expect = 3e-54
 Identities = 101/135 (74%), Positives = 114/135 (84%)
 Frame = +2

Query: 98  SATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAIL 277
           S +   + SLP+RVGHGFDLHRL  GY LIIGGIDIPH +GCEAHSDGDVLLH V DAIL
Sbjct: 16  SNSTAPSKSLPFRVGHGFDLHRLEPGYPLIIGGIDIPHDRGCEAHSDGDVLLHCVVDAIL 75

Query: 278 GALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHK 457
           GAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+PKLSPHK
Sbjct: 76  GALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYEIGNLDATLILQRPKLSPHK 135

Query: 458 ENIRNNLSAILGADP 502
           E IR+NLS +LGADP
Sbjct: 136 EAIRSNLSQLLGADP 150

[13][TOP]
>UniRef100_Q0Q5B3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Stevia rebaudiana RepID=Q0Q5B3_STERE
          Length = 231

 Score =  213 bits (542), Expect = 6e-54
 Identities = 108/152 (71%), Positives = 119/152 (78%), Gaps = 10/152 (6%)
 Frame = +2

Query: 77  RAASVVASATAVKA--------PS--LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCE 226
           R   V ASA AV+         PS  LP+RVGHGFDLHRL  GY LIIGGI+IPH +GCE
Sbjct: 47  RPVVVAASANAVEVEKPAVTGTPSKILPFRVGHGFDLHRLEPGYPLIIGGINIPHERGCE 106

Query: 227 AHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLG 406
           AHSDGDVLLH V DAILGAL LPDIGQ+FPD DPKWKGA S +F+KEAVRLM E GY LG
Sbjct: 107 AHSDGDVLLHCVVDAILGALGLPDIGQIFPDNDPKWKGAASSVFIKEAVRLMHEAGYELG 166

Query: 407 NLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           NLD T+I Q+PKLSPHKE IR+NLS +LGADP
Sbjct: 167 NLDATLILQRPKLSPHKEAIRDNLSLLLGADP 198

[14][TOP]
>UniRef100_A7BG58 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Citrus jambhiri RepID=A7BG58_CITJA
          Length = 237

 Score =  213 bits (542), Expect = 6e-54
 Identities = 100/136 (73%), Positives = 115/136 (84%)
 Frame = +2

Query: 95  ASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAI 274
           AS    K+ SLP+RVGHGFDLHRL  GY LIIGGI++PH +GCEAHSDGDVLLH V DAI
Sbjct: 69  ASIQPSKSKSLPFRVGHGFDLHRLEPGYPLIIGGINVPHERGCEAHSDGDVLLHCVVDAI 128

Query: 275 LGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPH 454
           LGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLMDE GY +GNLD T+I Q+PKLSP+
Sbjct: 129 LGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMDEAGYEIGNLDATLILQRPKLSPY 188

Query: 455 KENIRNNLSAILGADP 502
           KE IR +LS +LGADP
Sbjct: 189 KETIRTSLSELLGADP 204

[15][TOP]
>UniRef100_Q5J7B2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ginkgo biloba RepID=Q5J7B2_GINBI
          Length = 239

 Score =  213 bits (541), Expect = 8e-54
 Identities = 102/135 (75%), Positives = 111/135 (82%)
 Frame = +2

Query: 98  SATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAIL 277
           SA A  AP LP+RVGHGFDLHRL  G  LIIGGIDIPH +GC+AHSDGDVLLH V DAIL
Sbjct: 72  SAVAKSAPVLPFRVGHGFDLHRLEPGLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAIL 131

Query: 278 GALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHK 457
           GAL LPDIGQLFPD DPKW+GA S +FLKEAVRLM E GY LGNLD T+I Q+PKLSPHK
Sbjct: 132 GALGLPDIGQLFPDNDPKWRGAASSVFLKEAVRLMHEAGYELGNLDATLILQRPKLSPHK 191

Query: 458 ENIRNNLSAILGADP 502
           E IR NL  +LG+DP
Sbjct: 192 EAIRTNLCELLGSDP 206

[16][TOP]
>UniRef100_Q1EDG4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ginkgo biloba RepID=Q1EDG4_GINBI
          Length = 239

 Score =  213 bits (541), Expect = 8e-54
 Identities = 102/135 (75%), Positives = 111/135 (82%)
 Frame = +2

Query: 98  SATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAIL 277
           SA A  AP LP+RVGHGFDLHRL  G  LIIGGIDIPH +GC+AHSDGDVLLH V DAIL
Sbjct: 72  SAVAKSAPVLPFRVGHGFDLHRLEPGLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAIL 131

Query: 278 GALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHK 457
           GAL LPDIGQLFPD DPKW+GA S +FLKEAVRLM E GY LGNLD T+I Q+PKLSPHK
Sbjct: 132 GALGLPDIGQLFPDNDPKWRGAASSVFLKEAVRLMHEAGYELGNLDATLILQRPKLSPHK 191

Query: 458 ENIRNNLSAILGADP 502
           E IR NL  +LG+DP
Sbjct: 192 EAIRTNLCELLGSDP 206

[17][TOP]
>UniRef100_A9ZN13 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Hevea
           brasiliensis RepID=A9ZN13_HEVBR
          Length = 241

 Score =  213 bits (541), Expect = 8e-54
 Identities = 110/168 (65%), Positives = 124/168 (73%), Gaps = 1/168 (0%)
 Frame = +2

Query: 2   SLRGRSAFSSGRAAPKAFARVQRTCRAASVVASATAVKAP-SLPYRVGHGFDLHRLAEGY 178
           SLR  + FS   AA            A  V    T+ K P SLP+RVGHGFDLHRL  GY
Sbjct: 50  SLRTTTRFSISAAAGTT---------AVQVDGPTTSNKGPKSLPFRVGHGFDLHRLEPGY 100

Query: 179 KLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIF 358
            LIIGGI+IPH +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPD+DPKWKGA S +F
Sbjct: 101 PLIIGGINIPHERGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVF 160

Query: 359 LKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           +KEAVRLM E GY +GNLD T+I Q+PKLSPHKE IR+NL  +LGADP
Sbjct: 161 IKEAVRLMHEAGYDIGNLDATLILQRPKLSPHKEAIRDNLCQLLGADP 208

[18][TOP]
>UniRef100_A1KXW3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Hevea
           brasiliensis RepID=A1KXW3_HEVBR
          Length = 238

 Score =  212 bits (539), Expect = 1e-53
 Identities = 103/142 (72%), Positives = 116/142 (81%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAP-SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V    T+ K P SLP+RVGHGFDLHRL  GY LIIGGI+IPH +GCEAHSDGDVLLH
Sbjct: 64  AVQVDGPTTSNKGPKSLPFRVGHGFDLHRLEPGYPLIIGGINIPHERGCEAHSDGDVLLH 123

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 124 CVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYDIGNLDATLILQR 183

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE IR+NL  +LGADP
Sbjct: 184 PKLSPHKEAIRDNLCQLLGADP 205

[19][TOP]
>UniRef100_C5Y0Y7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Sorghum bicolor RepID=C5Y0Y7_SORBI
          Length = 225

 Score =  211 bits (538), Expect = 2e-53
 Identities = 104/162 (64%), Positives = 122/162 (75%)
 Frame = +2

Query: 17  SAFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGG 196
           SA  S R  P+ F+ V    +A    A A   K P+LP+RVGHGFDLHRL     LIIGG
Sbjct: 31  SAQPSLRLRPRPFSAVAAAVQAEHQPAVAATPKPPALPFRVGHGFDLHRLEPNLPLIIGG 90

Query: 197 IDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVR 376
           I+IPH +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S +F++EAV+
Sbjct: 91  INIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSSVFMREAVK 150

Query: 377 LMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           LM E GY LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 151 LMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 192

[20][TOP]
>UniRef100_B9GKD1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Fragment)
           n=1 Tax=Populus trichocarpa RepID=B9GKD1_POPTR
          Length = 187

 Score =  211 bits (538), Expect = 2e-53
 Identities = 102/142 (71%), Positives = 116/142 (81%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAP-SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V    T+ KA  +LP+RVGHGFDLHRL  GY LIIGGID+PH +GCEAHSDGDVLLH
Sbjct: 13  AIQVDGPTTSSKASKTLPFRVGHGFDLHRLEPGYPLIIGGIDVPHDRGCEAHSDGDVLLH 72

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DA+LGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 73  CVVDAVLGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYEIGNLDATLILQR 132

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE IR NLS +LGADP
Sbjct: 133 PKLSPHKEAIRANLSELLGADP 154

[21][TOP]
>UniRef100_B6E1X5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Hevea
           brasiliensis RepID=B6E1X5_HEVBR
          Length = 238

 Score =  211 bits (538), Expect = 2e-53
 Identities = 103/142 (72%), Positives = 116/142 (81%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAP-SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V    T+ K P SLP+RVGHGFDLHRL  GY LIIGGI+IPH +GCEAHSDGDVLLH
Sbjct: 64  AVQVDGPTTSNKGPKSLPFRVGHGFDLHRLEPGYPLIIGGINIPHERGCEAHSDGDVLLH 123

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 124 CVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYDIGNLDATLILQR 183

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE IR+NL  +LGADP
Sbjct: 184 PKLSPHKEVIRDNLCQLLGADP 205

[22][TOP]
>UniRef100_A9ZN12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Hevea
           brasiliensis RepID=A9ZN12_HEVBR
          Length = 237

 Score =  211 bits (537), Expect = 2e-53
 Identities = 103/142 (72%), Positives = 116/142 (81%), Gaps = 1/142 (0%)
 Frame = +2

Query: 80  AASVVASATAVKAP-SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           A  V    T+ K P SLP+RVGHGFDLHRL  GY LIIGGI+IPH +GCEAHSDGDVLLH
Sbjct: 63  ALQVDGPPTSSKGPKSLPFRVGHGFDLHRLEPGYPLIIGGINIPHERGCEAHSDGDVLLH 122

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T+I Q+
Sbjct: 123 CVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYDIGNLDATLILQR 182

Query: 437 PKLSPHKENIRNNLSAILGADP 502
           PKLSPHKE IR+NL  +LGADP
Sbjct: 183 PKLSPHKEVIRDNLCQLLGADP 204

[23][TOP]
>UniRef100_Q9M4W3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,
           chloroplastic n=1 Tax=Catharanthus roseus
           RepID=ISPF_CATRO
          Length = 236

 Score =  211 bits (536), Expect = 3e-53
 Identities = 110/176 (62%), Positives = 122/176 (69%), Gaps = 14/176 (7%)
 Frame = +2

Query: 17  SAFSSGRAAPKAFARVQRTCRAASVVASATAVKA------------PS--LPYRVGHGFD 154
           S     +  P       R  R  S+V SA A  A            PS  L +RVGHGFD
Sbjct: 28  SPVGGSKTTPSYIRLSTRQSRTLSLVVSAAASGAAVEAEPKFAAVTPSKILSFRVGHGFD 87

Query: 155 LHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKW 334
           LHRL  GY LIIGGI+IPH +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPDTDPKW
Sbjct: 88  LHRLEPGYPLIIGGINIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDTDPKW 147

Query: 335 KGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           KGA S +F+KEAVRLMDE GY LGNLD T+I Q+PK+SPHKE IR NL  +LGADP
Sbjct: 148 KGAPSSVFIKEAVRLMDEAGYELGNLDATLILQRPKVSPHKEAIRQNLCQLLGADP 203

[24][TOP]
>UniRef100_B6TSC0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Zea
           mays RepID=B6TSC0_MAIZE
          Length = 226

 Score =  207 bits (526), Expect = 4e-52
 Identities = 102/158 (64%), Positives = 117/158 (74%)
 Frame = +2

Query: 29  SGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIP 208
           S R  P+    V    +A    A A   K P+LP+RVGHGFDLHRL     LIIGGIDIP
Sbjct: 36  SMRLRPRPSPAVAAAVQAEHQPAVAATPKPPALPFRVGHGFDLHRLEPNLPLIIGGIDIP 95

Query: 209 HTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDE 388
           H +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S +F++EAV+LM E
Sbjct: 96  HDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSSVFMREAVKLMHE 155

Query: 389 KGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
            GY LGNLD T+I QKPK+SP KE IR NL  +LGADP
Sbjct: 156 AGYELGNLDATLILQKPKISPFKETIRLNLCNLLGADP 193

[25][TOP]
>UniRef100_B6TL41 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Zea
           mays RepID=B6TL41_MAIZE
          Length = 225

 Score =  206 bits (524), Expect = 7e-52
 Identities = 103/156 (66%), Positives = 119/156 (76%)
 Frame = +2

Query: 35  RAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHT 214
           R +P A A VQ    A    A   A K P+LP+RVGHGFDLHRL     LIIGGI+IPH 
Sbjct: 41  RPSPAAAAAVQ----AEHQPALTAAPKPPALPFRVGHGFDLHRLEPDLPLIIGGINIPHD 96

Query: 215 KGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKG 394
           +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPD+DP+WKGA S +F++EAV+LM E G
Sbjct: 97  RGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSSVFMREAVKLMHEAG 156

Query: 395 YVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           Y LGNLD T+I QKPK+SP KE IR+NL  +LGADP
Sbjct: 157 YELGNLDATLILQKPKISPFKETIRSNLCDLLGADP 192

[26][TOP]
>UniRef100_Q1ZZS9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Cephalotaxus fortunei RepID=Q1ZZS9_CEPFR
          Length = 250

 Score =  202 bits (514), Expect = 1e-50
 Identities = 97/137 (70%), Positives = 110/137 (80%)
 Frame = +2

Query: 86  SVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVT 265
           S   S+ A  AP LP+R+GHGFDLHRL     LIIGGI+IPH +GCEAHS GDVLLH V 
Sbjct: 79  SYTKSSKAAPAPVLPFRIGHGFDLHRLEPNLPLIIGGINIPHDRGCEAHSGGDVLLHCVV 138

Query: 266 DAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKL 445
           DAILGAL  PDIGQ+FPDTDPKWKGA S +F+KEAVRLM E GY LGNLD T+I Q+PKL
Sbjct: 139 DAILGALGFPDIGQIFPDTDPKWKGATSSVFVKEAVRLMHEAGYELGNLDATLILQRPKL 198

Query: 446 SPHKENIRNNLSAILGA 496
           SPHKE I++NL A+LGA
Sbjct: 199 SPHKEVIQSNLCALLGA 215

[27][TOP]
>UniRef100_Q00ZE9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ostreococcus tauri RepID=Q00ZE9_OSTTA
          Length = 206

 Score =  201 bits (510), Expect = 3e-50
 Identities = 99/163 (60%), Positives = 120/163 (73%), Gaps = 5/163 (3%)
 Frame = +2

Query: 20  AFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAE-----GYKL 184
           A + GR+     A      R + V A A+A K P LP+RVGHGFDLHRL         KL
Sbjct: 8   ARARGRSTTTTGATRVSNARRSRVRARASATKPPPLPFRVGHGFDLHRLESTTEFPDLKL 67

Query: 185 IIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLK 364
           IIGGI+IPH +GC AHSDGDVL+H V DAI GAL LPDIGQLFPDTDPKWKG  SD+F++
Sbjct: 68  IIGGIEIPHDRGCVAHSDGDVLMHCVVDAITGALGLPDIGQLFPDTDPKWKGQTSDVFVQ 127

Query: 365 EAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           EA+RLM  +GY LGN+DCT+IAQ+PK+SPHK+ IR N++ +LG
Sbjct: 128 EAIRLMKIEGYSLGNIDCTLIAQRPKISPHKDAIRKNVADVLG 170

[28][TOP]
>UniRef100_C6SZ46 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Glycine max RepID=C6SZ46_SOYBN
          Length = 227

 Score =  200 bits (508), Expect = 5e-50
 Identities = 92/132 (69%), Positives = 109/132 (82%)
 Frame = +2

Query: 104 TAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGA 283
           +A  +  LP+R+GHGFDLHRL  GY LIIGGI+IPH +GCEAHSDGDVLLH V DAILGA
Sbjct: 62  SATPSKLLPFRIGHGFDLHRLEPGYPLIIGGINIPHDRGCEAHSDGDVLLHCVVDAILGA 121

Query: 284 LCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKEN 463
           L LPDIGQ+FPD+DPKWKG  S +F+ E+VRLM E GY +GNLD T+I Q+PKLSPHK+ 
Sbjct: 122 LGLPDIGQIFPDSDPKWKGCASSVFIHESVRLMHEAGYEIGNLDATLILQRPKLSPHKDA 181

Query: 464 IRNNLSAILGAD 499
           I+ NLSA+LG D
Sbjct: 182 IKANLSALLGVD 193

[29][TOP]
>UniRef100_C0PT53 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Picea
           sitchensis RepID=C0PT53_PICSI
          Length = 241

 Score =  200 bits (508), Expect = 5e-50
 Identities = 102/169 (60%), Positives = 119/169 (70%)
 Frame = +2

Query: 2   SLRGRSAFSSGRAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYK 181
           S+RG+  F +     +  + V  +    +     +A  A  LP+R+GHGFDLHRL     
Sbjct: 44  SIRGQ--FLASVLKHEVISEVSASTVTGTETRGGSAKPAAVLPFRIGHGFDLHRLEPNLP 101

Query: 182 LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFL 361
           LIIGGI+IPH +GCEAHSDGDVLLH V DAILGAL LPDIGQLFPD DPKWKGA S +F+
Sbjct: 102 LIIGGINIPHDRGCEAHSDGDVLLHCVVDAILGALSLPDIGQLFPDNDPKWKGAPSSVFV 161

Query: 362 KEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADPPL 508
           KEAVRLM E GY LGNLD T+I Q+PKLSPHKE I  NL A+LGA   L
Sbjct: 162 KEAVRLMHEAGYELGNLDATLILQRPKLSPHKEAIITNLCALLGAHSSL 210

[30][TOP]
>UniRef100_A9TT70 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Fragment)
           n=1 Tax=Physcomitrella patens subsp. patens
           RepID=A9TT70_PHYPA
          Length = 179

 Score =  197 bits (501), Expect = 3e-49
 Identities = 94/130 (72%), Positives = 106/130 (81%)
 Frame = +2

Query: 113 KAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCL 292
           +AP LP+RVGHGFDLHRL  G  LIIGG++IPH +GCEAHSDGDVLLH V DAILGAL L
Sbjct: 17  QAPVLPFRVGHGFDLHRLEPGLPLIIGGVNIPHDRGCEAHSDGDVLLHCVVDAILGALGL 76

Query: 293 PDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRN 472
           PDIGQLFPD DPKW+GA S +F+ EAVR M   GYV+GNLD T+I Q+PKLSPHKE IR 
Sbjct: 77  PDIGQLFPDNDPKWRGAVSSVFVIEAVRRMKAAGYVIGNLDATLILQRPKLSPHKEAIRA 136

Query: 473 NLSAILGADP 502
           NL  +L ADP
Sbjct: 137 NLCELLEADP 146

[31][TOP]
>UniRef100_A4S497 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S497_OSTLU
          Length = 179

 Score =  196 bits (498), Expect = 8e-49
 Identities = 93/131 (70%), Positives = 108/131 (82%), Gaps = 5/131 (3%)
 Frame = +2

Query: 116 APSLPYRVGHGFDLHRLAEG-----YKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILG 280
           AP LP+RVGHGFDLHRL         KLIIGGI+IPH +GC AHSDGDVL+H V DAI G
Sbjct: 13  APVLPFRVGHGFDLHRLESTAEFPELKLIIGGIEIPHDRGCVAHSDGDVLMHCVVDAITG 72

Query: 281 ALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKE 460
           AL LPDIGQLFPDTDPKWKG  SD+F+KEAVRLM  +GY +GNLDCT+IAQ+PK+SPHK+
Sbjct: 73  ALGLPDIGQLFPDTDPKWKGQTSDVFVKEAVRLMKLEGYSIGNLDCTLIAQRPKISPHKD 132

Query: 461 NIRNNLSAILG 493
           NIR N++ +LG
Sbjct: 133 NIRANVAKVLG 143

[32][TOP]
>UniRef100_Q9CAK8-2 Isoform 2 of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,
           chloroplastic n=1 Tax=Arabidopsis thaliana
           RepID=Q9CAK8-2
          Length = 223

 Score =  194 bits (492), Expect = 4e-48
 Identities = 97/150 (64%), Positives = 112/150 (74%), Gaps = 1/150 (0%)
 Frame = +2

Query: 56  ARVQRTCRAASVVASATAVK-APSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAH 232
           A V     A  V  S T+ K   +LP+R+GHGFDLHRL  GY LIIGGI IPH +GCEAH
Sbjct: 49  ASVSAASSAVDVNESVTSEKPTKTLPFRIGHGFDLHRLEPGYPLIIGGIVIPHDRGCEAH 108

Query: 233 SDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNL 412
           SD         DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLMDE GY +GNL
Sbjct: 109 SD--------VDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNL 160

Query: 413 DCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           D T+I Q+PK+SPHKE IR+NLS +LGADP
Sbjct: 161 DATLILQRPKISPHKETIRSNLSKLLGADP 190

[33][TOP]
>UniRef100_A1X5Y0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Taxus
           x media RepID=A1X5Y0_9CONI
          Length = 247

 Score =  187 bits (475), Expect = 4e-46
 Identities = 94/166 (56%), Positives = 117/166 (70%), Gaps = 9/166 (5%)
 Frame = +2

Query: 26  SSGRAAPKAFARVQR-------TCRAASVVASATAVKA--PSLPYRVGHGFDLHRLAEGY 178
           S  + +P + AR  R        C+A+    + T   A  P+LP+R+GHGFDLHRL    
Sbjct: 47  SQPKRSPISIARFDREDEDGVVACKASPSTVTFTTKDASPPALPFRIGHGFDLHRLEPNL 106

Query: 179 KLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIF 358
            LIIGGI+IPH +GC+A+S+GDVLLH + DAILGAL LPDIGQ+FPD DPKWK A S +F
Sbjct: 107 PLIIGGINIPHGRGCDAYSEGDVLLHCIVDAILGALGLPDIGQIFPDPDPKWKAATSSVF 166

Query: 359 LKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGA 496
           + EA  LM E GY LGNLD T+I Q+PKL PHKE I++NL A+LGA
Sbjct: 167 VNEAAILMPEAGYELGNLDATLILQRPKLRPHKEVIQSNLCALLGA 212

[34][TOP]
>UniRef100_C1FJN6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Micromonas sp. RCC299 RepID=C1FJN6_9CHLO
          Length = 256

 Score =  181 bits (459), Expect = 3e-44
 Identities = 90/162 (55%), Positives = 111/162 (68%), Gaps = 5/162 (3%)
 Frame = +2

Query: 38  AAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLA-----EGYKLIIGGID 202
           A P A AR +     A  +A+   +    +P RVGHGFDLHR+         +L +GGI 
Sbjct: 29  AGPAAAARRRSVATRAVKLATGEVLDVKPVPMRVGHGFDLHRMELLSEMPDLELWLGGIK 88

Query: 203 IPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLM 382
           + H +GC AHSDGDVLLH V DAI GAL LPDIGQ FPD DPKWKG  SD+F+KEAVRLM
Sbjct: 89  LEHDRGCVAHSDGDVLLHCVFDAITGALGLPDIGQCFPDNDPKWKGCTSDVFIKEAVRLM 148

Query: 383 DEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADPPL 508
            + GY +GN+DCTIIAQ+PK+SPHK+ I+ NL+ +L  D  L
Sbjct: 149 RDSGYEMGNIDCTIIAQRPKISPHKKAIKENLAKLLECDEGL 190

[35][TOP]
>UniRef100_C1N0H8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Micromonas pusilla CCMP1545 RepID=C1N0H8_9CHLO
          Length = 162

 Score =  177 bits (448), Expect = 5e-43
 Identities = 83/127 (65%), Positives = 99/127 (77%), Gaps = 5/127 (3%)
 Frame = +2

Query: 134 RVGHGFDLHRLA-----EGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPD 298
           R+GHGFDLHR+       G +L +GGI + H +GC AHSDGDVLLH + DAI GAL +PD
Sbjct: 2   RIGHGFDLHRMELLTEMPGLELWLGGIKLEHDRGCVAHSDGDVLLHCIVDAITGALGMPD 61

Query: 299 IGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNL 478
           IGQLFPD DPKWKG  SD+F+ EA RLM E GY +GN+DCTIIAQ+PK+SPHKE IR NL
Sbjct: 62  IGQLFPDNDPKWKGCTSDVFVTEACRLMREAGYEIGNMDCTIIAQRPKISPHKEAIRANL 121

Query: 479 SAILGAD 499
           + +LGAD
Sbjct: 122 AKMLGAD 128

[36][TOP]
>UniRef100_B3F8G7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Fragment)
           n=1 Tax=Nicotiana langsdorffii x Nicotiana sanderae
           RepID=B3F8G7_NICLS
          Length = 135

 Score =  164 bits (415), Expect = 3e-39
 Identities = 77/102 (75%), Positives = 87/102 (85%)
 Frame = +2

Query: 197 IDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVR 376
           I+IPH +GCEAHSDGDVLLH V DAILGAL LPDIGQ+FPDTDPKWKGA S +F++EAVR
Sbjct: 1   INIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDTDPKWKGAPSSVFMEEAVR 60

Query: 377 LMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGADP 502
           LM E GY LGNLD T+I Q+PK+SPHKE IR NL  +LGADP
Sbjct: 61  LMHEAGYELGNLDATLILQRPKVSPHKEAIRANLCKLLGADP 102

[37][TOP]
>UniRef100_C0QQE6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Persephonella marina EX-H1 RepID=C0QQE6_PERMH
          Length = 168

 Score =  156 bits (394), Expect = 9e-37
 Identities = 73/125 (58%), Positives = 93/125 (74%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIG 304
           + YR+G GFD+HRL EG KLIIGG+ IP  KG +AHSDGD+  H +TDA+LGA+   DIG
Sbjct: 1   MEYRIGTGFDIHRLEEGRKLIIGGVQIPFEKGFKAHSDGDIFFHALTDALLGAIGYGDIG 60

Query: 305 QLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
           QLFPD+D KW+GA S IFLKEA R++ EKGY + N+DC I+ ++PKL P +E I  N + 
Sbjct: 61  QLFPDSDKKWEGADSSIFLKEASRIVKEKGYEIVNIDCYILLERPKLLPFREKIIENTAN 120

Query: 485 ILGAD 499
           IL  D
Sbjct: 121 ILQID 125

[38][TOP]
>UniRef100_B6DX86 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Guillardia theta RepID=B6DX86_GUITH
          Length = 225

 Score =  154 bits (389), Expect = 3e-36
 Identities = 80/150 (53%), Positives = 106/150 (70%), Gaps = 6/150 (4%)
 Frame = +2

Query: 68  RTCRAASVVASAT-AVKAPSLPYRVGHGFDLHRLAE----GYKLIIGGIDIPHTK-GCEA 229
           RT  ++   AS +  ++     +R+GHGFD+HRLA     G   +IGG+ + + + G EA
Sbjct: 40  RTASSSRASASRSHGLRMAEPAFRIGHGFDIHRLAPLEVAGQGCVIGGVKVENFELGTEA 99

Query: 230 HSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGN 409
           HSDGDVL H+VTDAILGAL LPDIGQL PDTDPKWKG  S+ FL EA +LMDE+GY + N
Sbjct: 100 HSDGDVLYHSVTDAILGALSLPDIGQLSPDTDPKWKGCDSEKFLAEAWKLMDERGYQVSN 159

Query: 410 LDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
           LD T+I ++PK+SP K  + +NLS +L A+
Sbjct: 160 LDVTLILERPKVSPIKSRMEDNLSRVLKAE 189

[39][TOP]
>UniRef100_Q747A0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter sulfurreducens RepID=ISPF_GEOSL
          Length = 157

 Score =  152 bits (385), Expect = 1e-35
 Identities = 71/123 (57%), Positives = 92/123 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HRL  G KLI+GG+DIPH  G   HSD DVLLH ++DAILGAL L DIG+ F
Sbjct: 2   RIGHGYDVHRLVAGRKLIVGGVDIPHELGLLGHSDADVLLHAISDAILGALALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+  + L   KG+ LGNLD TI+AQ+PK++PH   +R +++A L 
Sbjct: 62  PDTDPRYKGADSRALLRHVMELATRKGFHLGNLDATIVAQRPKMAPHIPLMREHIAADLM 121

Query: 494 ADP 502
           ADP
Sbjct: 122 ADP 124

[40][TOP]
>UniRef100_C3AY16 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Bacillus RepID=C3AY16_BACMY
          Length = 158

 Score =  150 bits (380), Expect = 4e-35
 Identities = 71/120 (59%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLLGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH EN+R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIENMRKRISELL 121

[41][TOP]
>UniRef100_C3AG86 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus mycoides Rock1-4 RepID=C3AG86_BACMY
          Length = 158

 Score =  150 bits (380), Expect = 4e-35
 Identities = 71/120 (59%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLLGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH EN+R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIENMRKRISELL 121

[42][TOP]
>UniRef100_C2Z1V8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Bacillus cereus RepID=C2Z1V8_BACCE
          Length = 158

 Score =  149 bits (376), Expect = 1e-34
 Identities = 71/120 (59%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S I L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAILLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[43][TOP]
>UniRef100_C2UPJ8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=3
           Tax=Bacillus cereus RepID=C2UPJ8_BACCE
          Length = 158

 Score =  149 bits (376), Expect = 1e-34
 Identities = 71/120 (59%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S I L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAILLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[44][TOP]
>UniRef100_A3Y5Q9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Marinomonas sp. MED121 RepID=A3Y5Q9_9GAMM
          Length = 162

 Score =  149 bits (376), Expect = 1e-34
 Identities = 70/125 (56%), Positives = 95/125 (76%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIG 304
           LP+R+GHGFD+H+  EG ++I+GG+ IP+  G  AHSDGDV+LH +TDAILGA  L DIG
Sbjct: 2   LPFRIGHGFDVHKFGEGDEIILGGVSIPYLHGLIAHSDGDVVLHALTDAILGAAALGDIG 61

Query: 305 QLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
           + FPDTDP + GA S + LK+A + + +KGY LGNLD TI+AQ PK++PH + +R N++A
Sbjct: 62  KHFPDTDPVFAGADSRVLLKKAYQEVLKKGYQLGNLDITIMAQAPKMAPHIDAMRANIAA 121

Query: 485 ILGAD 499
            L  D
Sbjct: 122 DLALD 126

[45][TOP]
>UniRef100_C2YKN9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus AH1271 RepID=C2YKN9_BACCE
          Length = 158

 Score =  149 bits (375), Expect = 1e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRQRISELL 121

[46][TOP]
>UniRef100_C2WGF5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus Rock4-2 RepID=C2WGF5_BACCE
          Length = 137

 Score =  149 bits (375), Expect = 1e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[47][TOP]
>UniRef100_B5UVY1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=3
           Tax=Bacillus cereus RepID=B5UVY1_BACCE
          Length = 158

 Score =  149 bits (375), Expect = 1e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[48][TOP]
>UniRef100_B1UXL4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus anthracis str. A0174 RepID=B1UXL4_BACAN
          Length = 159

 Score =  149 bits (375), Expect = 1e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[49][TOP]
>UniRef100_C3P9N2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=52
           Tax=Bacillus cereus group RepID=ISPF_BACAA
          Length = 158

 Score =  149 bits (375), Expect = 1e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[50][TOP]
>UniRef100_C2TRD9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus Rock1-3 RepID=C2TRD9_BACCE
          Length = 158

 Score =  148 bits (374), Expect = 2e-34
 Identities = 71/120 (59%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S I L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAILLQKVWGFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[51][TOP]
>UniRef100_B6G092 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium hiranonis DSM 13275 RepID=B6G092_9CLOT
          Length = 160

 Score =  148 bits (374), Expect = 2e-34
 Identities = 69/122 (56%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+HRL E  KLIIGG++IPH KG   HSD DVL H V D+ILGA+ + DIG+ F
Sbjct: 2   RVGMGYDVHRLVEDRKLIIGGVEIPHEKGLLGHSDADVLTHAVMDSILGAMAMGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDPK+KGA S   ++    +M E+GYV+GN+DCTIIAQ PK++PH   +R N + I+ 
Sbjct: 62  PDTDPKFKGADSLKLMEHVYEIMKEEGYVIGNIDCTIIAQAPKMAPHIPQMRENFARIMH 121

Query: 494 AD 499
            D
Sbjct: 122 TD 123

[52][TOP]
>UniRef100_Q73FC0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus ATCC 10987 RepID=ISPF_BACC1
          Length = 158

 Score =  148 bits (374), Expect = 2e-34
 Identities = 69/120 (57%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGG+ IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGVTIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[53][TOP]
>UniRef100_Q8XYW2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ralstonia solanacearum RepID=ISPF_RALSO
          Length = 168

 Score =  148 bits (373), Expect = 2e-34
 Identities = 70/123 (56%), Positives = 90/123 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLI+GG++IPHT+G   HSD D LLH +TDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + E GY +GN+D T+IAQKPKL+PH   +  NL+A LG
Sbjct: 67  PDTDPAFAGADSRVLLREAVRRVREAGYDVGNVDATVIAQKPKLAPHVPGMVANLAADLG 126

Query: 494 ADP 502
             P
Sbjct: 127 IAP 129

[54][TOP]
>UniRef100_B7HJ25 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus B4264 RepID=ISPF_BACC4
          Length = 158

 Score =  148 bits (373), Expect = 2e-34
 Identities = 70/120 (58%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWGFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[55][TOP]
>UniRef100_B0MSU3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Alistipes putredinis DSM 17216 RepID=B0MSU3_9BACT
          Length = 160

 Score =  147 bits (372), Expect = 3e-34
 Identities = 65/125 (52%), Positives = 90/125 (72%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIG 304
           + +R+G+G+D+H L EG  LI+GG++I H KGC AHSDGDV+LH ++DA+LGA  L DIG
Sbjct: 2   MKFRIGYGYDVHALGEGLPLILGGVEIEHAKGCIAHSDGDVVLHAISDALLGAAALGDIG 61

Query: 305 QLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
             FPDT  ++KGA S + L   V L+ EKGY +GN+DCTI  Q+PKL PH + +R  ++ 
Sbjct: 62  LHFPDTSDEFKGADSKLLLARCVELLREKGYAVGNVDCTISMQRPKLRPHIDRMRETIAR 121

Query: 485 ILGAD 499
            +G D
Sbjct: 122 TIGID 126

[56][TOP]
>UniRef100_O67089 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Aquifex aeolicus RepID=ISPF_AQUAE
          Length = 156

 Score =  147 bits (372), Expect = 3e-34
 Identities = 66/120 (55%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD H   EG  LI+GG++I    G + HSDGD LLH +TDAILGAL   DIG++F
Sbjct: 4   RIGFGFDSHEFVEGKLLILGGVEIEKDYGLKGHSDGDALLHAITDAILGALGERDIGEIF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
            DTDP+WK A S IFL++A+ +M EKG+ + N+DC I+A +PK++PHKE I+ +LS +LG
Sbjct: 64  KDTDPRWKNAPSRIFLEKALEVMSEKGFNISNIDCVIVADRPKIAPHKERIKESLSKLLG 123

[57][TOP]
>UniRef100_C2X5V6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Bacillus cereus group RepID=C2X5V6_BACCE
          Length = 158

 Score =  147 bits (371), Expect = 4e-34
 Identities = 69/120 (57%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IPH KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQ+PK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQQPKMAPHIESMRKRISELL 121

[58][TOP]
>UniRef100_B5S387 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ralstonia solanacearum MolK2 RepID=B5S387_RALSO
          Length = 168

 Score =  147 bits (370), Expect = 5e-34
 Identities = 69/120 (57%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLI+GG++IPHT+G   HSD D LLH +TDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + E GY +GN+D TIIAQ+PKL+PH   +  NL+A LG
Sbjct: 67  PDTDPAFAGADSRVLLREAVRRVREAGYAVGNVDATIIAQRPKLAPHVAGMVANLAADLG 126

[59][TOP]
>UniRef100_B9E8S0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Macrococcus caseolyticus JCSC5402 RepID=B9E8S0_MACCJ
          Length = 159

 Score =  146 bits (369), Expect = 7e-34
 Identities = 69/122 (56%), Positives = 91/122 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG  LIIGGI++ H KG   HSD DVLLH +TDAILGA+ L DIG+ F
Sbjct: 3   RIGYGYDVHQLVEGRTLIIGGIELEHDKGLLGHSDADVLLHAITDAILGAVSLGDIGKFF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD DPK+KGA S I LKEA + + + GY +GNLD TIIA+KPK  PH + +R +++ +L 
Sbjct: 63  PDDDPKYKGADSKILLKEAYQHVLKLGYEIGNLDATIIAEKPKFRPHIDAMRESIANVLN 122

Query: 494 AD 499
            D
Sbjct: 123 TD 124

[60][TOP]
>UniRef100_C3BWA9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus thuringiensis serovar tochigiensis BGSC 4Y1
           RepID=C3BWA9_BACTU
          Length = 158

 Score =  146 bits (369), Expect = 7e-34
 Identities = 69/120 (57%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPYEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[61][TOP]
>UniRef100_A3RPK1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Ralstonia solanacearum RepID=A3RPK1_RALSO
          Length = 168

 Score =  146 bits (369), Expect = 7e-34
 Identities = 69/120 (57%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLI+GG++IPHT+G   HSD D LLH +TDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + E GY +GN+D TIIAQ+PKL+PH   +  NL+A LG
Sbjct: 67  PDTDPVFAGADSRVLLREAVRRVREAGYAVGNVDATIIAQRPKLAPHVAGMVANLAADLG 126

[62][TOP]
>UniRef100_B1HNM6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Bacillales RepID=ISPF_LYSSC
          Length = 158

 Score =  146 bits (369), Expect = 7e-34
 Identities = 68/124 (54%), Positives = 93/124 (75%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H   EG  LIIGGI IPH KG   HSD DVLLHTVTDA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHAFEEGRPLIIGGITIPHEKGLVGHSDADVLLHTVTDAALGAIGEGDIGRH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S   L+   +++++KGY+LGN+DCTI+AQ+PK++P+ E ++N ++ +L
Sbjct: 62  FPDTDPAFKDADSAKLLEYIWKIVEDKGYILGNVDCTIMAQRPKMAPYIEQMQNRIAELL 121

Query: 491 GADP 502
            A+P
Sbjct: 122 HAEP 125

[63][TOP]
>UniRef100_A7GJZ8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cytotoxicus NVH 391-98 RepID=ISPF_BACCN
          Length = 158

 Score =  146 bits (369), Expect = 7e-34
 Identities = 69/120 (57%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQKPK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELL 121

[64][TOP]
>UniRef100_C8W821 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Atopobium parvulum DSM 20469 RepID=C8W821_ATOPD
          Length = 161

 Score =  146 bits (368), Expect = 9e-34
 Identities = 64/123 (52%), Positives = 91/123 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           ++GHG+D+HRL EG KLI+GG++IPH KG   HSD DVL H + DA+LGA+   DIGQLF
Sbjct: 5   KIGHGYDVHRLVEGRKLILGGVEIPHEKGLLGHSDADVLAHALMDALLGAMRAGDIGQLF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP ++GA S + L   ++L+ +KG+ L + DCT+ AQ PKL P++E +RN ++ ++G
Sbjct: 65  PDTDPAYEGADSMVLLSHVMQLVRDKGFELVDCDCTVAAQAPKLLPYREAMRNRMAEVMG 124

Query: 494 ADP 502
             P
Sbjct: 125 VTP 127

[65][TOP]
>UniRef100_C6NE79 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pectobacterium wasabiae WPP163 RepID=C6NE79_9ENTR
          Length = 165

 Score =  146 bits (368), Expect = 9e-34
 Identities = 71/116 (61%), Positives = 89/116 (76%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+T+G  AHSDGDV+LH VTDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYTQGLLAHSDGDVVLHAVTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R ++EKGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  PDTDPAFKGADSRGLLREAWRRINEKGYQLGNLDVTIIAQAPKMAPHIPQMRVNLA 117

[66][TOP]
>UniRef100_A8W1J0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus selenitireducens MLS10 RepID=A8W1J0_9BACI
          Length = 165

 Score =  146 bits (368), Expect = 9e-34
 Identities = 67/122 (54%), Positives = 91/122 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD+H+L EG  LI+GGI+IPH +G + HSD DVLLHT+ DA LGA+   DIG+ F
Sbjct: 2   RIGQGFDVHQLKEGRPLILGGIEIPHEQGLDGHSDADVLLHTIADACLGAVAEGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +K A S   L+   +++ EKGY LGNLDCTI+AQ+PK++PH + +R  ++ +L 
Sbjct: 62  PDTDPAFKDADSAKLLEHVWQIVKEKGYTLGNLDCTIMAQRPKMAPHIDAMRTRIAGLLE 121

Query: 494 AD 499
           AD
Sbjct: 122 AD 123

[67][TOP]
>UniRef100_B2UFT6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ralstonia pickettii 12J RepID=ISPF_RALPJ
          Length = 168

 Score =  146 bits (368), Expect = 9e-34
 Identities = 68/123 (55%), Positives = 89/123 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLI+GG++IPHT+G   HSD D LLH +TDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + + GY +GN+D T+IAQKPKL+PH   +  NL+  LG
Sbjct: 67  PDTDPAFAGADSRVLLREAVRRVHKAGYAVGNVDATVIAQKPKLAPHVPGMVANLAEDLG 126

Query: 494 ADP 502
             P
Sbjct: 127 IAP 129

[68][TOP]
>UniRef100_C6DDG1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pectobacterium carotovorum subsp. carotovorum PC1
           RepID=ISPF_PECCP
          Length = 165

 Score =  146 bits (368), Expect = 9e-34
 Identities = 71/116 (61%), Positives = 89/116 (76%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+T+G  AHSDGDV+LH VTDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYTQGLLAHSDGDVVLHAVTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R ++EKGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  PDTDPAFKGADSRGLLREAWRRINEKGYQLGNLDVTIIAQAPKMAPHIPQMRVNLA 117

[69][TOP]
>UniRef100_C6E7N8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter sp. M21 RepID=C6E7N8_GEOSM
          Length = 162

 Score =  145 bits (367), Expect = 1e-33
 Identities = 66/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HRL EG KLI+GG+D+P+ KG   HSD DVLLH ++DAILGA+   DIG+ F
Sbjct: 5   RIGHGYDVHRLVEGRKLILGGVDVPYAKGLLGHSDADVLLHAISDAILGAIGEGDIGRHF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+  + L D KGY +GN+D T++AQ+PKL+P  + +R N++  L 
Sbjct: 65  PDTDPAYKGADSIKLLQHVMGLADAKGYRIGNVDATVVAQRPKLAPFIQQMRQNIARALA 124

Query: 494 AD 499
            D
Sbjct: 125 TD 126

[70][TOP]
>UniRef100_B5EEK4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter bemidjiensis Bem RepID=B5EEK4_GEOBB
          Length = 162

 Score =  145 bits (367), Expect = 1e-33
 Identities = 66/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HRL EG KLI+GG+D+P+ KG   HSD DVLLH ++DAILGA+   DIG+ F
Sbjct: 5   RIGHGYDVHRLVEGRKLILGGVDVPYAKGLLGHSDADVLLHAISDAILGAIGEGDIGRHF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+  + L D KGY +GN+D T++AQ+PKL+P  + +R N++  L 
Sbjct: 65  PDTDPAYKGADSIKLLQHVMGLADAKGYRIGNVDATVVAQRPKLAPFIQQMRQNIARALA 124

Query: 494 AD 499
            D
Sbjct: 125 TD 126

[71][TOP]
>UniRef100_Q39ZL6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter metallireducens GS-15 RepID=ISPF_GEOMG
          Length = 157

 Score =  145 bits (367), Expect = 1e-33
 Identities = 69/122 (56%), Positives = 91/122 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H L EG KLI+GG+D+P+ +G   HSD DVLLH + DAILGAL L DIG+ F
Sbjct: 2   RIGHGYDVHCLVEGRKLILGGVDVPYERGLLGHSDADVLLHAIADAILGALALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+  + L  +KGYVLGN+D TI+AQ+PKL+P    +R NL+  L 
Sbjct: 62  PDTDPQFKGADSRKLLRHVMALAGQKGYVLGNVDATIVAQRPKLAPFIPEMRANLAEDLI 121

Query: 494 AD 499
           A+
Sbjct: 122 AE 123

[72][TOP]
>UniRef100_C6BIT4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ralstonia pickettii 12D RepID=C6BIT4_RALP1
          Length = 168

 Score =  145 bits (366), Expect = 2e-33
 Identities = 68/123 (55%), Positives = 89/123 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLI+GG++IPHT+G   HSD D LLH +TDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + + GY +GN+D T+IAQKPKL+PH   +  NL+  LG
Sbjct: 67  PDTDPAFAGADSRMLLREAVRRVHKAGYAVGNVDATVIAQKPKLAPHVPGMVANLAEDLG 126

Query: 494 ADP 502
             P
Sbjct: 127 IAP 129

[73][TOP]
>UniRef100_C2Q625 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus cereus R309803 RepID=C2Q625_BACCE
          Length = 158

 Score =  145 bits (366), Expect = 2e-33
 Identities = 68/120 (56%), Positives = 88/120 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H  AEG  LIIGGI IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHEFAEGRPLIIGGITIPYEKGLIGHSDADVLLHTIADACLGAIAAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L++    + E+GY LGNLDCTIIAQ+PK++PH E++R  +S +L
Sbjct: 62  FPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQRPKMAPHIESMRKRISELL 121

[74][TOP]
>UniRef100_Q3A8C7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pelobacter carbinolicus DSM 2380 RepID=ISPF_PELCD
          Length = 164

 Score =  145 bits (366), Expect = 2e-33
 Identities = 71/122 (58%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+L    KLI+GG+DIPHT G   HSD DVLLH + DAILGAL   DIG+ F
Sbjct: 3   RIGHGYDVHQLVAERKLILGGVDIPHTLGLLGHSDADVLLHAICDAILGALGEGDIGKHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KG  S   L E +RL + KGY LGNLD TIIAQ+PKL+P   N+R N++   G
Sbjct: 63  PDTDPAYKGISSIKLLHEVMRLAETKGYRLGNLDATIIAQRPKLAPFIGNMRENIAEACG 122

Query: 494 AD 499
            D
Sbjct: 123 TD 124

[75][TOP]
>UniRef100_Q6D1B4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pectobacterium atrosepticum RepID=ISPF_ERWCT
          Length = 165

 Score =  145 bits (365), Expect = 2e-33
 Identities = 70/116 (60%), Positives = 89/116 (76%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+T+G  AHSDGDV+LH VTDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYTQGLLAHSDGDVVLHAVTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R +++KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  PDTDPAFKGADSRGLLREAWRRINDKGYQLGNLDVTIIAQAPKMAPHIPQMRVNLA 117

[76][TOP]
>UniRef100_A6TWK9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Alkaliphilus metalliredigens QYMF RepID=ISPF_ALKMQ
          Length = 159

 Score =  145 bits (365), Expect = 2e-33
 Identities = 68/120 (56%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+HRL EG KLI+GG++IPH KG   HSD DVLLH + DA+LGA+ L DIG+ F
Sbjct: 2   RVGIGYDVHRLVEGRKLIVGGVEIPHEKGLLGHSDADVLLHAIKDALLGAVALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD K+KG  S   L E  R++ EK YV  N+D TIIAQ+PK++P+ E +R N++ +LG
Sbjct: 62  PDTDEKYKGESSLYLLNEVGRMLAEKAYVANNIDATIIAQEPKMAPYIELMRRNIAEVLG 121

[77][TOP]
>UniRef100_UPI00017F6075 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium difficile QCD-23m63 RepID=UPI00017F6075
          Length = 161

 Score =  144 bits (364), Expect = 3e-33
 Identities = 67/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+L E  KLIIGG++IPH KG   HSD DVL+H + D+ILGAL L DIG+ F
Sbjct: 2   RIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAIMDSILGALALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S   L+    L+  KGY +GN+D TIIAQ PK++P+ EN+R+N+S +L 
Sbjct: 62  PDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQSPKMAPYIENMRSNISKVLN 121

Query: 494 AD 499
            D
Sbjct: 122 TD 123

[78][TOP]
>UniRef100_A7Z0L3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus amyloliquefaciens FZB42 RepID=ISPF_BACA2
          Length = 158

 Score =  144 bits (364), Expect = 3e-33
 Identities = 71/123 (57%), Positives = 90/123 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGGI+IP+ KG   HSD DVLLHTV DA LGA    DIG+ 
Sbjct: 2   FRIGQGFDVHQLTEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAAGEGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP++K A S   L+    ++ EKGYVLGN+DCTIIAQKPK++PH + +R  ++  L
Sbjct: 62  FPDTDPEFKDADSFKLLQHVWNIVKEKGYVLGNIDCTIIAQKPKMAPHIDAMRKRIAEGL 121

Query: 491 GAD 499
            AD
Sbjct: 122 EAD 124

[79][TOP]
>UniRef100_A6BKL1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=Dorea
           longicatena DSM 13814 RepID=A6BKL1_9FIRM
          Length = 183

 Score =  144 bits (363), Expect = 3e-33
 Identities = 68/119 (57%), Positives = 89/119 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG  LI+GG+ IP+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLVEGRDLILGGVKIPYEKGLLGHSDADVLLHAIMDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDP +KGA S   L+E  R++DEK YV+GN+D TIIAQ+PK++PH E +R N++  L
Sbjct: 62  PDTDPAYKGASSIRLLEEVGRMIDEKLYVIGNIDATIIAQRPKMAPHIEQMRKNVAEAL 120

[80][TOP]
>UniRef100_Q1LLZ4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ralstonia metallidurans CH34 RepID=ISPF_RALME
          Length = 168

 Score =  144 bits (363), Expect = 3e-33
 Identities = 68/120 (56%), Positives = 86/120 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L  G KLI+GG+DIPH +G   HSD D LLH VTDA+ GA  L DIG+ F
Sbjct: 7   RIGQGYDVHALVPGRKLILGGVDIPHDRGLLGHSDADALLHAVTDALFGAAALGDIGRHF 66

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP + GA S + L+EAVR + E GY +GN+D T+IAQKPKL+PH   +  NL+  LG
Sbjct: 67  PDTDPNFAGADSRVLLREAVRRVREAGYEIGNVDATVIAQKPKLAPHISGMVANLAEDLG 126

[81][TOP]
>UniRef100_B3E280 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter lovleyi SZ RepID=ISPF_GEOLS
          Length = 157

 Score =  144 bits (362), Expect = 5e-33
 Identities = 67/122 (54%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HRL E  KLI+GG+DIP  KG   HSD DVLLH + DA+LGAL + DIG+ F
Sbjct: 2   RIGHGYDVHRLVEDRKLIMGGVDIPWEKGLLGHSDADVLLHAIADALLGALAMGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+  V L+  +GY +GNLD TIIAQ+PK++PH + +R N++   G
Sbjct: 62  PDTDPAFKGADSMKLLEHVVGLIRTQGYAVGNLDATIIAQRPKMAPHIQAMRENVARACG 121

Query: 494 AD 499
            +
Sbjct: 122 VE 123

[82][TOP]
>UniRef100_A1TMI3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Acidovorax citrulli AAC00-1 RepID=A1TMI3_ACIAC
          Length = 165

 Score =  143 bits (361), Expect = 6e-33
 Identities = 66/125 (52%), Positives = 90/125 (72%)
 Frame = +2

Query: 128 PYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           P+R+G G+D+H L  G +L+IGG+DIPH+ G   HSD DVLLH VTDA+LGA+ L DIG 
Sbjct: 5   PFRIGEGWDIHALVPGRRLVIGGVDIPHSMGLLGHSDADVLLHAVTDALLGAVGLGDIGS 64

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAI 487
            FPDTD ++KGA S + L EA R + E+G+ +GN+D T+IAQ P+L+PH   +R  ++  
Sbjct: 65  HFPDTDERFKGADSMVLLVEAARRVRERGHEIGNIDSTVIAQAPRLAPHIPAMREGMARS 124

Query: 488 LGADP 502
           LG  P
Sbjct: 125 LGLQP 129

[83][TOP]
>UniRef100_C3WM07 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. 2_1_31 RepID=C3WM07_9FUSO
          Length = 161

 Score =  143 bits (361), Expect = 6e-33
 Identities = 68/125 (54%), Positives = 90/125 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG +L++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHRLVEGRRLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL PH ++IR+N++ IL 
Sbjct: 63  PDNDENLKNIDSAILLKKINNIMKEKNYRIVNLDSIIVIQKPKLRPHIDSIRDNIAKILE 122

Query: 494 ADPPL 508
            +P L
Sbjct: 123 IEPEL 127

[84][TOP]
>UniRef100_C9XIG0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Clostridium difficile RepID=C9XIG0_CLODI
          Length = 161

 Score =  143 bits (360), Expect = 8e-33
 Identities = 66/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+L E  KLIIGG++IPH KG   HSD DVL+H + D+ILGAL L DIG+ F
Sbjct: 2   RIGLGYDVHKLTENRKLIIGGVEIPHDKGLLGHSDADVLIHAIMDSILGALALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S   L+    L+  KGY +GN+D TIIAQ PK++P+ E++R+N+S +L 
Sbjct: 62  PDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQSPKMAPYIESMRSNISKVLN 121

Query: 494 AD 499
            D
Sbjct: 122 TD 123

[85][TOP]
>UniRef100_C0BX63 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium hylemonae DSM 15053 RepID=C0BX63_9CLOT
          Length = 182

 Score =  143 bits (360), Expect = 8e-33
 Identities = 67/122 (54%), Positives = 91/122 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG +LI+GG+ IPH KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLVEGRELIVGGVKIPHEKGLLGHSDADVLLHAIMDALLGAAALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP+++GA S   L+    L++E+ YV+GN+D TIIAQ+PK++PH E +R N++A L 
Sbjct: 62  PDTDPEYEGASSMKLLERVGGLVEEELYVIGNIDATIIAQRPKMAPHIEKMRENVAAALH 121

Query: 494 AD 499
            D
Sbjct: 122 LD 123

[86][TOP]
>UniRef100_A4ER72 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/
           2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Roseobacter sp. SK209-2-6 RepID=A4ER72_9RHOB
          Length = 380

 Score =  143 bits (360), Expect = 8e-33
 Identities = 67/152 (44%), Positives = 95/152 (62%)
 Frame = +2

Query: 44  PKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGC 223
           P+ FAR +R                  +  R+G+G+D+HR   G  +I+ G++IPH +G 
Sbjct: 206 PEDFARAERILGTQE-----------KMDIRLGNGYDVHRFGPGDSVILCGVEIPHERGL 254

Query: 224 EAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVL 403
           + HSD DV +H VTDAI GAL   DIG+ FP +DP+WKGA S+IFLK A  L  E GY +
Sbjct: 255 QGHSDADVGMHAVTDAIYGALAQGDIGRHFPPSDPQWKGAASEIFLKHAAELAAEMGYQI 314

Query: 404 GNLDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
            N+DCT++ + PK+ PH E +R  ++AI+G D
Sbjct: 315 SNIDCTLVCEYPKVGPHAEKMRQTMAAIVGID 346

[87][TOP]
>UniRef100_A1AJY3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pelobacter propionicus DSM 2379 RepID=ISPF_PELPD
          Length = 158

 Score =  143 bits (360), Expect = 8e-33
 Identities = 69/119 (57%), Positives = 86/119 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+L EG KLI+GG+DIP  KG   HSD DVLLH + DAILGAL   DIG+ F
Sbjct: 2   RIGHGYDVHKLVEGRKLIMGGVDIPWEKGLLGHSDADVLLHAIADAILGALGEGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDP +KGA S   L+    L   KGY LGNLD TIIAQ+PK++PH   +R N++ +L
Sbjct: 62  PDTDPAYKGADSLKLLEHVANLAIAKGYCLGNLDATIIAQRPKMAPHIPAMRENIARVL 120

[88][TOP]
>UniRef100_Q1YSS4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YSS4_9GAMM
          Length = 157

 Score =  142 bits (359), Expect = 1e-32
 Identities = 66/117 (56%), Positives = 85/117 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR   G KLI+GG+ IP+  G  AHSDGDVL+H + DA+LGA  L DIGQ F
Sbjct: 2   RIGHGYDVHRFGPGDKLILGGVSIPYEHGFVAHSDGDVLIHALIDALLGAAALGDIGQHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
           PDTD KW+GA S   L   V ++  KGY LGN+D TI+AQ+PK+ PH + +R NL+A
Sbjct: 62  PDTDAKWQGANSRQLLTAVVAMIASKGYKLGNVDITIVAQQPKMLPHLDKMRLNLAA 118

[89][TOP]
>UniRef100_C3WRE8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. 4_1_13 RepID=C3WRE8_9FUSO
          Length = 160

 Score =  142 bits (359), Expect = 1e-32
 Identities = 69/125 (55%), Positives = 89/125 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHRLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ +NIR+N++ IL 
Sbjct: 63  PDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDSIIVIQKPKLRPYIDNIRDNIAKILE 122

Query: 494 ADPPL 508
            D  L
Sbjct: 123 IDSEL 127

[90][TOP]
>UniRef100_A5G939 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter uraniireducens Rf4 RepID=ISPF_GEOUR
          Length = 157

 Score =  142 bits (359), Expect = 1e-32
 Identities = 67/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+L E  KLI+GG+DIP+ +G   HSD DVLLH ++DAILGA+   DIG+ F
Sbjct: 2   RIGHGYDVHKLVENRKLILGGVDIPYERGLLGHSDADVLLHAISDAILGAIGEGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L   + L   KGY +GNLD TI+AQ+PKL+PH   +R N++  L 
Sbjct: 62  PDTDPAYKGADSIKLLMHVMALAVGKGYAIGNLDATIVAQRPKLAPHIPQMRENIARALK 121

Query: 494 AD 499
           AD
Sbjct: 122 AD 123

[91][TOP]
>UniRef100_Q47EL1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Dechloromonas aromatica RCB RepID=ISPF_DECAR
          Length = 160

 Score =  142 bits (359), Expect = 1e-32
 Identities = 66/124 (53%), Positives = 92/124 (74%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +RVG G+D+H+L +G KLI+GG++IPH  G   HSD D LLH +TDA+LGA+ L DIG+ 
Sbjct: 3   FRVGQGYDVHKLVDGRKLILGGVEIPHPTGLLGHSDADALLHAITDALLGAVALGDIGRH 62

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP++KGA S + L+ AV L+ E+G+   N+D T+IAQ+PKL+PH   +  N++A L
Sbjct: 63  FPDTDPRYKGADSRVLLRAAVALLAERGWRPVNVDATLIAQQPKLAPHAVAMVANVAADL 122

Query: 491 GADP 502
           G  P
Sbjct: 123 GISP 126

[92][TOP]
>UniRef100_Q18CD3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium difficile 630 RepID=ISPF_CLOD6
          Length = 161

 Score =  142 bits (359), Expect = 1e-32
 Identities = 66/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+L E  KLIIGG++IPH KG   HSD DVL+H + D+ILGAL L DIG+ F
Sbjct: 2   RIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAIMDSILGALALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S   L+    L+  KGY +GN+D TIIAQ PK++P+ E++R+N+S +L 
Sbjct: 62  PDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQSPKMAPYIESMRSNISKVLN 121

Query: 494 AD 499
            D
Sbjct: 122 TD 123

[93][TOP]
>UniRef100_Q1IVA8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Candidatus Koribacter versatilis Ellin345
           RepID=ISPF_ACIBL
          Length = 155

 Score =  142 bits (359), Expect = 1e-32
 Identities = 63/123 (51%), Positives = 87/123 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG GFD H   EG  L IGG+ IPHT G   HSDGDVLLH +TDA+LGA+   DIG  F
Sbjct: 3   RVGLGFDSHEFREGIPLRIGGLTIPHTHGLSGHSDGDVLLHAITDALLGAVAAGDIGAFF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P +DPKWKGA S +F++EA+R ++  GY +GN+DC+++   PK+ PH + I+ +++ +L 
Sbjct: 63  PPSDPKWKGANSVVFIEEAMRHIETAGYRVGNVDCSLVLNAPKIGPHAKAIQESVAKLLK 122

Query: 494 ADP 502
            +P
Sbjct: 123 IEP 125

[94][TOP]
>UniRef100_C6AJW3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Aggregatibacter aphrophilus NJ8700
           RepID=C6AJW3_AGGAN
          Length = 159

 Score =  142 bits (358), Expect = 1e-32
 Identities = 69/122 (56%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       LIIGG+ IP  KG  AHSDGDV LH +TDA+LGA+ L DIG+LF
Sbjct: 3   RIGHGFDVHAFGTDNPLIIGGVTIPFDKGFIAHSDGDVALHALTDALLGAVALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S + L+EA R + EKGYV+GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKGADSRVLLREAYRQVQEKGYVVGNVDVTIIAQAPKMRPHIDAMRALIAQDLS 122

Query: 494 AD 499
            D
Sbjct: 123 VD 124

[95][TOP]
>UniRef100_C7G6V0 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Roseburia intestinalis L1-82 RepID=C7G6V0_9FIRM
          Length = 181

 Score =  142 bits (358), Expect = 1e-32
 Identities = 68/119 (57%), Positives = 85/119 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG  LIIGG+ IPHT G   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLVEGRDLIIGGVKIPHTLGLLGHSDADVLLHAIMDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDPK+KG  S   L+    L+ EKGY++ N+D TIIAQKPK+ PH E +  N++A L
Sbjct: 62  PDTDPKYKGISSMKLLEHVAGLIAEKGYIVENIDATIIAQKPKMRPHIEQMEKNIAAAL 120

[96][TOP]
>UniRef100_C0FW60 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Roseburia inulinivorans DSM 16841 RepID=C0FW60_9FIRM
          Length = 181

 Score =  142 bits (358), Expect = 1e-32
 Identities = 67/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG  LI+GG+ IPHT G   HSD DVLLH V DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLVEGRDLILGGVKIPHTLGLLGHSDADVLLHAVMDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KG  S   L+   +L++EKGY++ N+D TIIAQKPK+ P+ E +  N++A L 
Sbjct: 62  PDTDPQYKGISSIKLLEHVTKLIEEKGYIVENIDATIIAQKPKMRPYIEEMEKNIAAALH 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[97][TOP]
>UniRef100_Q06756 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus subtilis RepID=ISPF_BACSU
          Length = 158

 Score =  142 bits (358), Expect = 1e-32
 Identities = 70/123 (56%), Positives = 91/123 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGGI+IP+ KG   HSD DVLLHTV DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP++K A S   L+    ++ +KGYVLGN+DCTIIAQKPK+ P+ E++R  ++  L
Sbjct: 62  FPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGL 121

Query: 491 GAD 499
            AD
Sbjct: 122 EAD 124

[98][TOP]
>UniRef100_A3QC80 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella loihica PV-4 RepID=ISPF_SHELP
          Length = 161

 Score =  142 bits (357), Expect = 2e-32
 Identities = 68/122 (55%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LI+GG+++P+  G  AHSDGDV+LH ++DAILGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGGELPLILGGVEVPYDTGLVAHSDGDVVLHAISDAILGAMALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S + L+   +L  +KGY LGNLD TIIAQ PK+ PH + IR  LSA L 
Sbjct: 64  PDTDPDFKGADSRVLLRHCYQLALDKGYRLGNLDVTIIAQAPKMLPHIQAIRECLSADLE 123

Query: 494 AD 499
           +D
Sbjct: 124 SD 125

[99][TOP]
>UniRef100_Q02R99 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas aeruginosa UCBPP-PA14 RepID=ISPF_PSEAB
          Length = 157

 Score =  142 bits (357), Expect = 2e-32
 Identities = 64/120 (53%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  EG  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+  V ++ EKG+ +GN+D TI+AQ PK++PH E +R +++  LG
Sbjct: 62  PDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGSIAEDLG 121

[100][TOP]
>UniRef100_Q12A11 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Polaromonas sp. JS666 RepID=Q12A11_POLSJ
          Length = 169

 Score =  141 bits (356), Expect = 2e-32
 Identities = 71/136 (52%), Positives = 93/136 (68%), Gaps = 1/136 (0%)
 Frame = +2

Query: 98  SATAVKAPSLP-YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAI 274
           S  +  A  LP +R+G G+D H L  G KLIIGG++IPH  G   HSD DVLLH +TDA+
Sbjct: 3   SVPSTPANPLPHFRIGEGWDTHALVAGRKLIIGGVEIPHPVGLLGHSDADVLLHAITDAL 62

Query: 275 LGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPH 454
           LGA  L DIG  FPDTD ++KGA S + L EA RL+ ++GY +GN+D T+IAQ PKL+PH
Sbjct: 63  LGAAGLGDIGSHFPDTDVRFKGADSMVLLAEAGRLLADRGYSIGNIDSTVIAQAPKLAPH 122

Query: 455 KENIRNNLSAILGADP 502
              +R  ++  LG +P
Sbjct: 123 ILAMRARIAQALGLEP 138

[101][TOP]
>UniRef100_B9MD06 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Diaphorobacter sp. TPSY RepID=B9MD06_DIAST
          Length = 167

 Score =  141 bits (356), Expect = 2e-32
 Identities = 65/129 (50%), Positives = 90/129 (69%)
 Frame = +2

Query: 107 AVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGAL 286
           A  A  + +R+G G+D+H L  G +L+IGG++IPHT G   HSD DVLLH +TDA+LGA 
Sbjct: 3   AADAMGMNFRIGEGWDVHALVPGRRLVIGGVEIPHTMGLLGHSDADVLLHAITDALLGAA 62

Query: 287 CLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENI 466
            L DIG  FPDTD ++KGA S   L+EA R + +KGY +GN+D T++AQ P+L+ H   +
Sbjct: 63  ALGDIGSHFPDTDARFKGADSVALLEEAARRVGDKGYAIGNIDSTVVAQAPRLAAHIPAM 122

Query: 467 RNNLSAILG 493
           R  ++A LG
Sbjct: 123 RERIAAALG 131

[102][TOP]
>UniRef100_C6MMN7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacter sp. M18 RepID=C6MMN7_9DELT
          Length = 158

 Score =  141 bits (356), Expect = 2e-32
 Identities = 64/122 (52%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+HRL EG KLI+GG+D+P+ KG   HSD DVLLH ++DAILGA+   DIG+ F
Sbjct: 2   RIGQGYDVHRLVEGRKLILGGVDVPYAKGLLGHSDADVLLHAISDAILGAIGEGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+  + L + KGY +GN+D T++AQ+PKL+P  E +R+N++  L 
Sbjct: 62  PDTDPAYKGADSIKLLRHVMDLAEAKGYRIGNVDATVVAQRPKLAPFIEQMRSNIARALS 121

Query: 494 AD 499
            +
Sbjct: 122 TE 123

[103][TOP]
>UniRef100_C4V397 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Selenomonas flueggei ATCC 43531 RepID=C4V397_9FIRM
          Length = 158

 Score =  141 bits (356), Expect = 2e-32
 Identities = 66/120 (55%), Positives = 86/120 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+HRL EG KLI+GG+D+P+ KG   HSD DVLLH ++DA+LGA  L DIGQ F
Sbjct: 3   RVGIGYDVHRLVEGRKLILGGVDVPYEKGLLGHSDADVLLHAISDALLGAAALGDIGQHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++ GA S   L E VRL+  +GY +GN+D  I+AQ PKL P+   +R N++  LG
Sbjct: 63  PDTDARYAGAESGTLLSEVVRLVQTEGYAIGNVDACIVAQAPKLMPYIPAMRENIAGRLG 122

[104][TOP]
>UniRef100_B8GQ78 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Thioalkalivibrio sp. HL-EbGR7 RepID=ISPF_THISH
          Length = 160

 Score =  141 bits (356), Expect = 2e-32
 Identities = 65/120 (54%), Positives = 87/120 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H    G  +++GG+ IPH K   AHSDGDVL+H + DA+LGA  L DIG+ F
Sbjct: 5   RIGHGYDVHAFKAGGHVVLGGVRIPHAKAFAAHSDGDVLIHALCDALLGAAALGDIGRHF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S + L+  V L+ E+GY +GN+D TIIAQ PK++PH E +R NL+  LG
Sbjct: 65  PDTDPAYKGADSRVLLRRVVELLHEQGYRVGNVDATIIAQAPKMAPHIEAMRANLADDLG 124

[105][TOP]
>UniRef100_C6J669 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Paenibacillus sp. oral taxon 786 str. D14
           RepID=C6J669_9BACL
          Length = 162

 Score =  141 bits (355), Expect = 3e-32
 Identities = 70/126 (55%), Positives = 89/126 (70%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +RVG GFD+H+L EG   IIGG+ IP+ KG   HSD DVLLH ++DAILGAL L DIG+ 
Sbjct: 2   FRVGQGFDVHQLVEGRPCIIGGVHIPYEKGLLGHSDADVLLHAISDAILGALGLGDIGRH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP +K A S + L+    +  EKGY +GNLD TIIAQKPK++PH   +   ++  L
Sbjct: 62  FPDTDPAFKDADSVVLLQRVWDMAIEKGYRIGNLDATIIAQKPKMAPHIPQMVEVIARTL 121

Query: 491 GADPPL 508
           GA+P L
Sbjct: 122 GAEPEL 127

[106][TOP]
>UniRef100_C2BXE3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Listeria grayi DSM 20601 RepID=C2BXE3_LISGR
          Length = 157

 Score =  141 bits (355), Expect = 3e-32
 Identities = 65/122 (53%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+LAE  KLIIGGI+IPH  G   HSD DVLLH +TDAI+GA+C  DIG  F
Sbjct: 3   RIGQGYDVHQLAENRKLIIGGIEIPHELGLLGHSDADVLLHAITDAIIGAVCKRDIGYFF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L    + + + GY LGNLDCT+IA+KPK++P+ + +R +++ +LG
Sbjct: 63  PDTDDQYKDADSSQLLSIIWKEIQQDGYQLGNLDCTVIAEKPKMAPYIKAMREHIAELLG 122

Query: 494 AD 499
           A+
Sbjct: 123 AE 124

[107][TOP]
>UniRef100_Q1I652 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas entomophila L48 RepID=ISPF_PSEE4
          Length = 157

 Score =  141 bits (355), Expect = 3e-32
 Identities = 63/119 (52%), Positives = 89/119 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  +G  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDP++KGA S + L+  V ++D KG+ +GN+D TI+AQ PK++PH E +R  ++A L
Sbjct: 62  PDTDPQFKGADSRVLLRHVVGIVDNKGWKVGNVDATIVAQAPKMAPHIETMRQQIAADL 120

[108][TOP]
>UniRef100_C7XT55 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. 3_1_36A2 RepID=C7XT55_9FUSO
          Length = 160

 Score =  140 bits (354), Expect = 4e-32
 Identities = 68/125 (54%), Positives = 89/125 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHRLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL 
Sbjct: 63  PDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDTIIVIQKPKLRPYIDSIRDNIAKILE 122

Query: 494 ADPPL 508
            D  L
Sbjct: 123 IDSEL 127

[109][TOP]
>UniRef100_C3WYB7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. 7_1 RepID=C3WYB7_9FUSO
          Length = 165

 Score =  140 bits (354), Expect = 4e-32
 Identities = 68/125 (54%), Positives = 89/125 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHRLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL 
Sbjct: 63  PDNDKNLKDIDSAILLKKINNIMKEKNYKIVNLDTIIVIQKPKLRPYIDSIRDNIAKILE 122

Query: 494 ADPPL 508
            D  L
Sbjct: 123 IDSEL 127

[110][TOP]
>UniRef100_A8UU41 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8UU41_9AQUI
          Length = 164

 Score =  140 bits (354), Expect = 4e-32
 Identities = 68/124 (54%), Positives = 87/124 (70%)
 Frame = +2

Query: 122 SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDI 301
           S+ +R G GFD H   +G  L IGG+ I    G + HSDGDVLLH +TDAILGAL  PDI
Sbjct: 5   SVHFRTGLGFDSHEFEKGKPLYIGGVCIDFPLGLKGHSDGDVLLHAITDAILGALGEPDI 64

Query: 302 GQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           G+LF D D +WKGA S++FL+EA+  + EKGY L NLDC +IA KPK++P+K  I+  LS
Sbjct: 65  GELFSDRDERWKGAPSELFLREALERVREKGYELINLDCVLIADKPKIAPYKGKIKGKLS 124

Query: 482 AILG 493
            + G
Sbjct: 125 ELTG 128

[111][TOP]
>UniRef100_A1HTI4 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Thermosinus carboxydivorans Nor1 RepID=A1HTI4_9FIRM
          Length = 385

 Score =  140 bits (354), Expect = 4e-32
 Identities = 70/155 (45%), Positives = 100/155 (64%)
 Frame = +2

Query: 35  RAAPKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHT 214
           +  P ++  ++ T     V+A+A   +   +  RVG G+D+HRL  G KLI+GG++IP+ 
Sbjct: 199 KLVPGSYRNLKITTPEDMVIAAALLGEGKGM--RVGIGYDVHRLVVGRKLILGGVEIPYE 256

Query: 215 KGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKG 394
            G E HSD DVLLH + DA+LGA  L DIG+ FPDTDP++KGA S   L     ++ E G
Sbjct: 257 YGLEGHSDADVLLHAIKDALLGAAALGDIGRHFPDTDPRYKGASSLKLLARVKEILAENG 316

Query: 395 YVLGNLDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
           Y  GN+D T+IAQKPKL+P+   +  N++ +LG D
Sbjct: 317 YETGNVDATVIAQKPKLAPYIAQMNANIARVLGID 351

[112][TOP]
>UniRef100_A6V1G1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas aeruginosa PA7 RepID=ISPF_PSEA7
          Length = 157

 Score =  140 bits (354), Expect = 4e-32
 Identities = 64/120 (53%), Positives = 88/120 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  EG  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFGEGDYITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+  V ++ EKG+ +GN+D TI+AQ PK++PH E +R  ++  LG
Sbjct: 62  PDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLG 121

[113][TOP]
>UniRef100_Q65PD1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus licheniformis ATCC 14580 RepID=ISPF_BACLD
          Length = 158

 Score =  140 bits (354), Expect = 4e-32
 Identities = 69/123 (56%), Positives = 90/123 (73%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGGI IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHQLVEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAVGEGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP++K A S   L+    ++ EKGY LGNLDCTIIAQKPK++P+ E++R  ++  L
Sbjct: 62  FPDTDPEFKDADSFKLLRHVWMIVKEKGYTLGNLDCTIIAQKPKMAPYIEDMRARIAEGL 121

Query: 491 GAD 499
            A+
Sbjct: 122 EAE 124

[114][TOP]
>UniRef100_C6CAX8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Dickeya dadantii Ech703 RepID=C6CAX8_DICDC
          Length = 165

 Score =  140 bits (353), Expect = 5e-32
 Identities = 68/116 (58%), Positives = 85/116 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+ +G  AHSDGDV+LH VTDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYERGLLAHSDGDVVLHAVTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KG  S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  PDTDPAYKGIDSRELLREAWRRIVSKGYALGNLDVTIIAQAPKMAPHIPQMRVNLA 117

[115][TOP]
>UniRef100_A4XWR4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas mendocina ymp RepID=ISPF_PSEMY
          Length = 157

 Score =  140 bits (353), Expect = 5e-32
 Identities = 64/122 (52%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  EG  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA+ L DIG+ F
Sbjct: 2   RIGHGYDVHRFGEGDFITLGGVRIPHKFGLVAHSDGDVLLHALSDALLGAVALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+  + L+  KGY +GN+D TIIAQ PK++PH +++R  ++  LG
Sbjct: 62  PDTDPTFKGADSRALLRHVMSLVRGKGYAVGNVDATIIAQAPKMAPHIQSMRERIAEDLG 121

Query: 494 AD 499
            +
Sbjct: 122 VE 123

[116][TOP]
>UniRef100_B7V8C1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=4
           Tax=Pseudomonas aeruginosa RepID=ISPF_PSEA8
          Length = 157

 Score =  140 bits (353), Expect = 5e-32
 Identities = 64/120 (53%), Positives = 88/120 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  EG  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+  V ++ EKG+ +GN+D TI+AQ PK++PH E +R  ++  LG
Sbjct: 62  PDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLG 121

[117][TOP]
>UniRef100_B0TYX5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Francisella philomiragia subsp. philomiragia ATCC
           25017 RepID=ISPF_FRAP2
          Length = 159

 Score =  140 bits (353), Expect = 5e-32
 Identities = 64/123 (52%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYK-LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDI 301
           + +R+GHG+D+H+     K +I+GGI+IP+  G EAHSDGDVL+H + DAILGALCL DI
Sbjct: 1   MSFRIGHGYDVHKFTSTKKNIILGGIEIPYEMGLEAHSDGDVLIHALCDAILGALCLGDI 60

Query: 302 GQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           G+ FPDTD ++K   S  FL E  +++D+K Y + N+DCTIIAQ PK+ PH E ++  L+
Sbjct: 61  GKHFPDTDMEYKNTDSKFFLAEIKKMLDDKEYSISNIDCTIIAQAPKMLPHIEKMKACLA 120

Query: 482 AIL 490
           ++L
Sbjct: 121 SVL 123

[118][TOP]
>UniRef100_Q9KGF7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus halodurans RepID=ISPF_BACHD
          Length = 157

 Score =  140 bits (353), Expect = 5e-32
 Identities = 69/122 (56%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG GFD+H+ AEG  LIIGG++IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ F
Sbjct: 3   RVGQGFDVHQFAEGRLLIIGGVEIPYEKGLLGHSDADVLLHTIADAALGAIGEGDIGKHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +K A S   L     L+ EKGY LGN+DCTIIAQKPK++PH   +R  ++ +L 
Sbjct: 63  PDTDPHFKDADSAKLLSAVWELVKEKGYTLGNVDCTIIAQKPKMAPHIPAMRARIAELLE 122

Query: 494 AD 499
           A+
Sbjct: 123 AE 124

[119][TOP]
>UniRef100_C4KZS0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Exiguobacterium sp. AT1b RepID=C4KZS0_EXISA
          Length = 157

 Score =  140 bits (352), Expect = 7e-32
 Identities = 64/122 (52%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD+H  AEG  LI+GGI+IPH +G   HSD DVLLHT+ DA LGA+   DIG+ F
Sbjct: 2   RIGQGFDVHAFAEGRPLILGGIEIPHERGLLGHSDADVLLHTIADAALGAIAAGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++K A S + L+   +L+ ++GYVLGN+D T++AQ+PKL P+ + +R  ++ +L 
Sbjct: 62  PDTDPEFKDADSKVLLRHVWQLVKDQGYVLGNVDATVMAQRPKLRPYIDEMRAVIAELLE 121

Query: 494 AD 499
           AD
Sbjct: 122 AD 123

[120][TOP]
>UniRef100_A6SXV3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Janthinobacterium sp. Marseille RepID=A6SXV3_JANMA
          Length = 168

 Score =  140 bits (352), Expect = 7e-32
 Identities = 67/130 (51%), Positives = 91/130 (70%)
 Frame = +2

Query: 113 KAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCL 292
           +A +LP+R+G G+D H L EG KLIIGG+ IPH+ G   HSD DVLLH +TDA+ GA  L
Sbjct: 5   QATALPFRIGQGYDCHALVEGRKLIIGGVTIPHSTGLLGHSDADVLLHAITDALFGAAAL 64

Query: 293 PDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRN 472
            DIG+ FPDT  ++ GA S + L+EAV+ +   GY +GN+D TIIAQ+PK+ PH   +  
Sbjct: 65  GDIGRHFPDTAVEFAGADSRVLLREAVKRVAAAGYRIGNVDATIIAQRPKMVPHIPTMVA 124

Query: 473 NLSAILGADP 502
           +++A LG  P
Sbjct: 125 HIAADLGVAP 134

[121][TOP]
>UniRef100_C9R1U5 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Aggregatibacter actinomycetemcomitans D11S-1
           RepID=C9R1U5_ACTAC
          Length = 159

 Score =  140 bits (352), Expect = 7e-32
 Identities = 68/122 (55%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       LIIGG+ IP  KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGTNNPLIIGGVTIPFDKGFIAHSDGDVALHALTDALLGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S + L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKGADSRVLLREAYRQVQEKGYCVGNVDVTIIAQAPKMRPHIDAMRALIAQDLA 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[122][TOP]
>UniRef100_C9KNS3 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Mitsuokella multacida DSM 20544 RepID=C9KNS3_9FIRM
          Length = 158

 Score =  140 bits (352), Expect = 7e-32
 Identities = 66/120 (55%), Positives = 86/120 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R G G+D+HRL EG KLIIGG++IPH  G   HSD DVLLH ++DA+LGA  L DIG+ F
Sbjct: 3   RFGMGYDVHRLVEGRKLIIGGVEIPHALGLLGHSDADVLLHAISDALLGAAALGDIGRHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP+++GA S   L E  RL+ EKGY +GN+D TI+AQKPK+      +  N++ +LG
Sbjct: 63  PDTDPRYEGADSMKLLAEVRRLLAEKGYRIGNVDATIVAQKPKMKDFIPKMNENIATVLG 122

[123][TOP]
>UniRef100_C4UT23 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia rohdei ATCC 43380 RepID=C4UT23_YERRO
          Length = 160

 Score =  140 bits (352), Expect = 7e-32
 Identities = 70/116 (60%), Positives = 84/116 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 5   RIGHGFDVHKFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 65  PDTDPTFKGADSRGLLREAYRRILAKGYQLGNLDITIIAQAPKMAPHIPQMRVNLA 120

[124][TOP]
>UniRef100_B9XIA9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=bacterium Ellin514 RepID=B9XIA9_9BACT
          Length = 159

 Score =  140 bits (352), Expect = 7e-32
 Identities = 64/118 (54%), Positives = 88/118 (74%)
 Frame = +2

Query: 137 VGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLFP 316
           VG G+D+H+L EG KLI+GG++IPHTKG E HSD DVL+H + DAILGA+   DIG  FP
Sbjct: 4   VGIGYDVHQLVEGRKLILGGVEIPHTKGLEGHSDADVLMHAICDAILGAIGEVDIGHFFP 63

Query: 317 DTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           +TDP+W+GA S++FL EA R +  +G  + N+D T+IAQ+PK+ PH   ++ N+ A L
Sbjct: 64  NTDPRWRGAPSNVFLNEAARQVRLRGARIINIDATLIAQQPKIFPHIGQMKVNIGAAL 121

[125][TOP]
>UniRef100_A9GXP8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Roseobacter litoralis Och 149 RepID=A9GXP8_9RHOB
          Length = 159

 Score =  140 bits (352), Expect = 7e-32
 Identities = 61/120 (50%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+GFD+H    G  + + G+DIPH +G   HSD DV +HTVTDAI GAL   DIG+ F
Sbjct: 4   RLGNGFDVHAFGPGDHVTLCGVDIPHAQGLVGHSDADVAMHTVTDAIYGALAAGDIGRHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P +DP+WKGA SD+FLK AV L  E+G+ + N+DCT+I + PK+ PH + +R  ++ I+G
Sbjct: 64  PPSDPQWKGAASDVFLKHAVALASEQGFEINNIDCTLICEFPKIGPHAQAMREKMAEIIG 123

[126][TOP]
>UniRef100_B4WQC5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WQC5_9SYNE
          Length = 158

 Score =  139 bits (351), Expect = 9e-32
 Identities = 64/123 (52%), Positives = 86/123 (69%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+GFD+HRL  G KLI+GGIDIPH++G   HSD D L H + DA+LGAL L DIG  F
Sbjct: 4   RIGNGFDVHRLHAGRKLILGGIDIPHSQGLLGHSDADALTHAIMDAMLGALSLGDIGVYF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P  DPKW GA S + L +  RL+ ++G+ + N+D  +IA+KPKL+PH  N+R  L+  L 
Sbjct: 64  PPDDPKWAGADSQVLLAQVNRLVGDRGWHVCNIDSVVIAEKPKLNPHIPNMRTRLATTLS 123

Query: 494 ADP 502
            +P
Sbjct: 124 IEP 126

[127][TOP]
>UniRef100_B0P082 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium sp. SS2/1 RepID=B0P082_9CLOT
          Length = 158

 Score =  139 bits (351), Expect = 9e-32
 Identities = 67/123 (54%), Positives = 88/123 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG  LI+GG++IP+ KG   HSD DVLLH +TDAILGA  L DIG+ F
Sbjct: 2   RVGMGYDVHQLVEGRDLILGGVNIPYEKGLLGHSDADVLLHAITDAILGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +  A S   L E VRL++EKGY +GN+D T+IAQ+P+L  +   ++ N+S  L 
Sbjct: 62  PDTDPAYHNADSMKLLAEVVRLIEEKGYEIGNVDATVIAQRPRLLNYIPTMKENISKTLK 121

Query: 494 ADP 502
            DP
Sbjct: 122 VDP 124

[128][TOP]
>UniRef100_B0NCP1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium scindens ATCC 35704 RepID=B0NCP1_EUBSP
          Length = 181

 Score =  139 bits (351), Expect = 9e-32
 Identities = 65/122 (53%), Positives = 92/122 (75%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG KLI+GG++IP+ KG   HSD DVL+H V DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLTEGRKLILGGVEIPYDKGLLGHSDADVLVHAVMDALLGAAALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   L+   +L+++K YV+GN+D TII Q+PK++P+ E +R N++ +L 
Sbjct: 62  PDTDPEYKGASSMKLLEHVGKLVEDKLYVIGNIDATIIVQRPKMAPYIEAMRANVANVLH 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[129][TOP]
>UniRef100_A0KU85 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=3
           Tax=Shewanella RepID=ISPF_SHESA
          Length = 159

 Score =  139 bits (351), Expect = 9e-32
 Identities = 66/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+  E   LI+ G+++P+  G  AHSDGDV+LH ++DAILGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGEARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S + L+    L   KG+ LGNLD TIIAQ PK++PH E++R  L+A L 
Sbjct: 64  PDTDAAYKGADSRVLLRHCYALARAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLN 123

Query: 494 AD 499
           AD
Sbjct: 124 AD 125

[130][TOP]
>UniRef100_C1DU19 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Sulfurihydrogenibium azorense Az-Fu1
           RepID=C1DU19_SULAA
          Length = 160

 Score =  139 bits (350), Expect = 1e-31
 Identities = 67/119 (56%), Positives = 89/119 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+DLH+L EG KLII G++IP  KG  AHSDGD+  H +TDA+LGA+   DIGQLF
Sbjct: 4   RVGIGYDLHKLEEGRKLIIAGVEIPSDKGFLAHSDGDIFFHALTDALLGAVGYGDIGQLF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PD+D K+K A S+IFLKEA R++D+K Y + N+D  II +KPK+ P++E +  N + IL
Sbjct: 64  PDSDKKFKDASSEIFLKEAKRIIDDKKYKIVNIDGVIIIEKPKILPYREKMIENTAKIL 122

[131][TOP]
>UniRef100_Q2B1J2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus sp. NRRL B-14911 RepID=Q2B1J2_9BACI
          Length = 159

 Score =  139 bits (350), Expect = 1e-31
 Identities = 67/123 (54%), Positives = 89/123 (72%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGGI+IP+ KG   HSD DVLLHT+ DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHQLTEGRPLIIGGIEIPYEKGLLGHSDADVLLHTIADACLGAIGEGDIGRH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTDP++K A S   L+   +++DEKGY L N DCTIIAQ PK++P+   +R  ++ +L
Sbjct: 62  FPDTDPEFKDADSAKLLEHVWKIVDEKGYKLVNADCTIIAQMPKMAPYIGQMRERIAELL 121

Query: 491 GAD 499
            AD
Sbjct: 122 QAD 124

[132][TOP]
>UniRef100_C6YVT8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Francisella philomiragia subsp. philomiragia ATCC
           25015 RepID=C6YVT8_9GAMM
          Length = 159

 Score =  139 bits (350), Expect = 1e-31
 Identities = 65/123 (52%), Positives = 89/123 (72%), Gaps = 1/123 (0%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYK-LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDI 301
           + +R+GHG+D+H+     K +IIGGI+IP+  G EAHSDGDVL+H + DAILGALCL DI
Sbjct: 1   MSFRIGHGYDVHKFTSTKKNIIIGGIEIPYKMGLEAHSDGDVLIHALCDAILGALCLGDI 60

Query: 302 GQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           G+ FPDTD ++K   S  FL E  +++D K Y + N+DCTIIAQ PK+ PH E ++  L+
Sbjct: 61  GKHFPDTDMEYKNTDSKFFLAEIKKMLDHKEYSISNIDCTIIAQAPKMLPHIEKMKACLA 120

Query: 482 AIL 490
            +L
Sbjct: 121 NVL 123

[133][TOP]
>UniRef100_C6QRY2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacillus sp. Y4.1MC1 RepID=C6QRY2_9BACI
          Length = 158

 Score =  139 bits (350), Expect = 1e-31
 Identities = 65/120 (54%), Positives = 87/120 (72%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGG+ IP+ KG   HSD DVLLH V DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHQLVEGRPLIIGGVRIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTD ++K A S + LK+   L+  +GY L NLDCT+IAQKPK++PH E ++ N++ +L
Sbjct: 62  FPDTDERYKDADSALLLKQVWELVKRQGYKLVNLDCTVIAQKPKMAPHIEQMKENIAKLL 121

[134][TOP]
>UniRef100_C6JJ42 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium varium ATCC 27725 RepID=C6JJ42_FUSVA
          Length = 157

 Score =  139 bits (350), Expect = 1e-31
 Identities = 66/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H LAEG KLI+GG++IPHTKG   HSDGDVL+H + DA+LGAL L DIGQ F
Sbjct: 3   RIGNGYDVHVLAEGRKLILGGVEIPHTKGVLGHSDGDVLVHAIMDAMLGALALGDIGQHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD K++   S I LK    L+ E+GY + NLD  I+ QKPK+ P+ E +R  ++ +L 
Sbjct: 63  PDTDMKYENIDSTILLKRVKELIAERGYKIINLDSIIVLQKPKVKPYIEAMRKRIAEVLE 122

Query: 494 AD 499
            D
Sbjct: 123 ID 124

[135][TOP]
>UniRef100_C4SJA2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia frederiksenii ATCC 33641 RepID=C4SJA2_YERFR
          Length = 160

 Score =  139 bits (350), Expect = 1e-31
 Identities = 69/116 (59%), Positives = 84/116 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 5   RIGHGFDVHKFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R +L+
Sbjct: 65  PDTDPAFKGADSRALLREAYRRILAKGYQLGNLDITIIAQAPKMAPHIPQMRVHLA 120

[136][TOP]
>UniRef100_A5ZXA3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ruminococcus obeum ATCC 29174 RepID=A5ZXA3_9FIRM
          Length = 161

 Score =  139 bits (350), Expect = 1e-31
 Identities = 65/120 (54%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L EG KLI+GG+DIP  KG   HSD DVL+H V DA+LGA  L DIG+ F
Sbjct: 4   RVGMGYDVHKLTEGRKLILGGVDIPWEKGLLGHSDADVLIHAVMDALLGAAALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KG  S   L     L+ ++GY +GN+D T+IAQKPK++PH   +R N++  LG
Sbjct: 64  PDTDPAYKGISSIKLLVHVAELLRKQGYAVGNIDATVIAQKPKMAPHIPQMRKNMADALG 123

[137][TOP]
>UniRef100_B2K578 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia pseudotuberculosis PB1/+ RepID=ISPF_YERPB
          Length = 162

 Score =  139 bits (350), Expect = 1e-31
 Identities = 71/118 (60%), Positives = 85/118 (72%), Gaps = 2/118 (1%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYK--LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           R+GHGFD+H+  E     LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+
Sbjct: 2   RIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGK 61

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           LFPDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  LFPDTDPAFKGADSRGLLREAYRCILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLA 119

[138][TOP]
>UniRef100_Q8EBR3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella oneidensis RepID=ISPF_SHEON
          Length = 159

 Score =  139 bits (350), Expect = 1e-31
 Identities = 66/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+  E   LI+ G+++P+  G  AHSDGDV+LH ++DAILGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGEPRPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S + L+    L   KG+ LGNLD TIIAQ PK++PH E++R  L+A L 
Sbjct: 64  PDTDAAYKGADSRVLLRHCYALAKAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLN 123

Query: 494 AD 499
           AD
Sbjct: 124 AD 125

[139][TOP]
>UniRef100_B0TK07 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella halifaxensis HAW-EB4 RepID=ISPF_SHEHH
          Length = 159

 Score =  139 bits (350), Expect = 1e-31
 Identities = 67/122 (54%), Positives = 88/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LI+GG+D+P+  G  AHSDGDV LH ++DAILGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGGEPPLILGGVDVPYEVGLIAHSDGDVALHAISDAILGAMALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S + L+   +L  + G+ L NLD TIIAQ PK++PH E IR  L+A L 
Sbjct: 64  PDTDPEFKGADSRVLLRHCYQLATDMGFSLSNLDVTIIAQAPKMAPHIEAIRKVLAADLV 123

Query: 494 AD 499
           AD
Sbjct: 124 AD 125

[140][TOP]
>UniRef100_C5D3P3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Geobacillus sp. WCH70 RepID=ISPF_GEOSW
          Length = 158

 Score =  139 bits (350), Expect = 1e-31
 Identities = 66/120 (55%), Positives = 87/120 (72%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LIIGG+ IP+ KG   HSD DVLLH V DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHQLVEGRPLIIGGVRIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGKH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTD  +K A S + LK+   L+ ++GY L NLDCTIIAQKPK++PH E ++ N++ +L
Sbjct: 62  FPDTDECYKDADSALLLKQVWELVKQQGYELANLDCTIIAQKPKMAPHIEQMKENIANLL 121

[141][TOP]
>UniRef100_B1YGS6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Exiguobacterium sibiricum 255-15 RepID=B1YGS6_EXIS2
          Length = 161

 Score =  139 bits (349), Expect = 1e-31
 Identities = 67/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD+H  AE  KLI+GGI+IPHTKG   HSD DVLLHT+ DA LGA+   DIG+ F
Sbjct: 4   RIGQGFDVHAFAEDRKLILGGIEIPHTKGLLGHSDADVLLHTIADAALGAIAAGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++K A S   L+    L+  +GY LGNLD T+IAQ PKL P+ + +R  ++ +L 
Sbjct: 64  PDTDPEFKDADSAKLLQHVYALVKAQGYELGNLDATVIAQAPKLRPYIDTMRARIAELLE 123

Query: 494 AD 499
           AD
Sbjct: 124 AD 125

[142][TOP]
>UniRef100_C4U7B8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia aldovae ATCC 35236 RepID=C4U7B8_YERAL
          Length = 165

 Score =  139 bits (349), Expect = 1e-31
 Identities = 71/118 (60%), Positives = 85/118 (72%), Gaps = 2/118 (1%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYK--LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           R+GHGFD+H+  E     LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+
Sbjct: 5   RIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGK 64

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           LFPDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 65  LFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLA 122

[143][TOP]
>UniRef100_B9NQS5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/
           2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Rhodobacteraceae bacterium KLH11 RepID=B9NQS5_9RHOB
          Length = 376

 Score =  139 bits (349), Expect = 1e-31
 Identities = 61/131 (46%), Positives = 90/131 (68%)
 Frame = +2

Query: 101 ATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILG 280
           A  +    +  R+G+G+D+HR  +G  +I+ G+ IPHT+G + HSD DV +H VTDAI G
Sbjct: 210 AERIMGTDMDVRLGNGYDVHRFGDGDHVILCGVKIPHTRGLQGHSDADVGMHAVTDAIYG 269

Query: 281 ALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKE 460
           AL   DIGQ FP +DP+WKGA S IFL+ AV L ++ GY + N+DCT++ + PK+ P+ E
Sbjct: 270 ALAQGDIGQHFPPSDPQWKGAASRIFLRHAVELAEQMGYRISNVDCTLVCEHPKIGPYAE 329

Query: 461 NIRNNLSAILG 493
            +R  ++ I+G
Sbjct: 330 AMRAEMAHIMG 340

[144][TOP]
>UniRef100_A7FLX7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=19
           Tax=Yersinia RepID=ISPF_YERP3
          Length = 162

 Score =  139 bits (349), Expect = 1e-31
 Identities = 71/118 (60%), Positives = 85/118 (72%), Gaps = 2/118 (1%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYK--LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           R+GHGFD+H+  E     LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+
Sbjct: 2   RIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGK 61

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           LFPDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R NL+
Sbjct: 62  LFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLA 119

[145][TOP]
>UniRef100_A6LQ55 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium beijerinckii NCIMB 8052 RepID=ISPF_CLOB8
          Length = 158

 Score =  139 bits (349), Expect = 1e-31
 Identities = 64/122 (52%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+HRL E  KLI+GG++IP+ KG   HSD DVL+H + D++LGA  L DIG+ F
Sbjct: 2   RIGLGYDVHRLVENRKLILGGVEIPYEKGLLGHSDADVLIHAIIDSLLGACALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++ G  S I L+E  +L+ + GY + N+D TIIAQKPK+ PH EN+R N+S  L 
Sbjct: 62  PDTDSRFSGISSIILLEETGKLLLKSGYAINNIDATIIAQKPKMLPHIENMRKNISIALN 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[146][TOP]
>UniRef100_Q3A9N8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=ISPF_CARHZ
          Length = 163

 Score =  139 bits (349), Expect = 1e-31
 Identities = 65/119 (54%), Positives = 84/119 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H L EG KLIIGG++IP TKG   HSD DVL H + DA LG+L L DIGQLF
Sbjct: 4   RIGFGYDVHPLVEGRKLIIGGVEIPFTKGLLGHSDADVLYHAIADAFLGSLALGDIGQLF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PD D +++G  S + L+E  R + E+GY L NLD  I+AQKPKL P  + +R NL+ +L
Sbjct: 64  PDNDERYRGIDSGLLLQEVYRRVRERGYCLNNLDAVIVAQKPKLLPFIQKMRENLAVLL 122

[147][TOP]
>UniRef100_UPI0001B52D03 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. D11 RepID=UPI0001B52D03
          Length = 165

 Score =  138 bits (348), Expect = 2e-31
 Identities = 66/125 (52%), Positives = 89/125 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG +L++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHKLVEGRRLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL 
Sbjct: 63  PDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDSIIVIQKPKLRPYIDSIRDNIAKILE 122

Query: 494 ADPPL 508
            D  L
Sbjct: 123 IDSEL 127

[148][TOP]
>UniRef100_C6CLT1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Dickeya zeae Ech1591 RepID=C6CLT1_DICZE
          Length = 165

 Score =  138 bits (348), Expect = 2e-31
 Identities = 65/116 (56%), Positives = 86/116 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+ +G  AHSDGDV+LH VTDA+LGA  + DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYERGLLAHSDGDVVLHAVTDALLGAAAMGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP ++G  S   L+EA R + +KGY LGNLD TIIAQ PK++PH   +R N++
Sbjct: 62  PDTDPAYRGIDSRELLREAWRRITDKGYQLGNLDVTIIAQAPKMAPHIPQMRVNIA 117

[149][TOP]
>UniRef100_D0BUA7 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium sp. 3_1_33 RepID=D0BUA7_9FUSO
          Length = 165

 Score =  138 bits (348), Expect = 2e-31
 Identities = 67/125 (53%), Positives = 89/125 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG KL++GG+++P+TKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHRLVEGRKLMLGGVEVPYTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL 
Sbjct: 63  PDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDTIIVIQKPKLRPYIDSIRDNIAKILE 122

Query: 494 ADPPL 508
            D  L
Sbjct: 123 IDSEL 127

[150][TOP]
>UniRef100_C8QLF0 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Dickeya dadantii Ech586 RepID=C8QLF0_DICDA
          Length = 165

 Score =  138 bits (348), Expect = 2e-31
 Identities = 65/116 (56%), Positives = 86/116 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+ +G  AHSDGDV+LH VTDA+LGA  + DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYERGLLAHSDGDVVLHAVTDALLGAAAMGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP ++G  S   L+EA R + +KGY LGNLD TIIAQ PK++PH   +R N++
Sbjct: 62  PDTDPAYRGIDSRELLREAWRRITDKGYELGNLDVTIIAQAPKMAPHIPQMRVNIA 117

[151][TOP]
>UniRef100_C5ENC4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridiales bacterium 1_7_47FAA RepID=C5ENC4_9FIRM
          Length = 180

 Score =  138 bits (348), Expect = 2e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+LAE   LI+GG+ IP+ KG   HSD DVL+H V DA+LGA  L DIGQ F
Sbjct: 2   RIGQGYDVHKLAEDRSLILGGVAIPYEKGLLGHSDADVLVHAVMDALLGAAALGDIGQHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KG  S   L+    L+DEKGYV+ N+D TIIAQKPKL+P++  +  N++  L 
Sbjct: 62  PDTDPAYKGISSIELLRRVGELLDEKGYVIENIDATIIAQKPKLAPYRPQMAANIAEALH 121

Query: 494 AD 499
            D
Sbjct: 122 LD 123

[152][TOP]
>UniRef100_B7C8Q7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Eubacterium biforme DSM 3989 RepID=B7C8Q7_9FIRM
          Length = 161

 Score =  138 bits (348), Expect = 2e-31
 Identities = 63/122 (51%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G   D+H+L EG KLI+GG++I H+KG   HSD DVL+H V ++ILGAL L D+G+ F
Sbjct: 5   RIGQAVDIHQLQEGRKLILGGVEIEHSKGLLGHSDADVLVHAVGESILGALALGDLGKHF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDPK+KGA S   L     +M+E GY +GN+D TI+A++PK++PH   +R N++A+L 
Sbjct: 65  PDTDPKYKGANSLDLLAHIYEMMNEMGYQIGNVDATILAERPKMAPHIMAMRKNIAAVLH 124

Query: 494 AD 499
            D
Sbjct: 125 CD 126

[153][TOP]
>UniRef100_B2PZ71 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Providencia stuartii ATCC 25827 RepID=B2PZ71_PROST
          Length = 170

 Score =  138 bits (348), Expect = 2e-31
 Identities = 67/116 (57%), Positives = 85/116 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      +IIGG+ IP+  G  AHSDGDV+LH VTDAILGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGDGPIIIGGVRIPYEHGLLAHSDGDVVLHAVTDAILGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S I LK+A   + EKGY +GN+D TI+AQ PK+ PH   +R N++
Sbjct: 62  PDTDPAYKGADSRILLKKAYCHVREKGYSIGNIDVTIMAQAPKMLPHIPQMRVNIA 117

[154][TOP]
>UniRef100_A9E400 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/
           2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Oceanibulbus indolifex HEL-45 RepID=A9E400_9RHOB
          Length = 376

 Score =  138 bits (348), Expect = 2e-31
 Identities = 63/135 (46%), Positives = 90/135 (66%)
 Frame = +2

Query: 95  ASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAI 274
           A A  +    +  R G+GFD+H    G  + + G+DIPHT G   HSD DV LHTVTDAI
Sbjct: 208 ARAARILETRMDIRTGNGFDVHAFGPGDHVTLCGLDIPHTHGLVGHSDADVALHTVTDAI 267

Query: 275 LGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPH 454
            GAL   DIGQ FP +DP+WKGARSDIFL+ A ++  + G+ L ++DCT+I + PK+ PH
Sbjct: 268 YGALARGDIGQHFPPSDPQWKGARSDIFLRHAAQMARDMGFTLTHVDCTLICETPKIGPH 327

Query: 455 KENIRNNLSAILGAD 499
            + +R +++ ++G +
Sbjct: 328 VQPMRASMAEMVGLE 342

[155][TOP]
>UniRef100_A8SSU2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Coprococcus eutactus ATCC 27759 RepID=A8SSU2_9FIRM
          Length = 189

 Score =  138 bits (348), Expect = 2e-31
 Identities = 66/119 (55%), Positives = 88/119 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+HRL EG KLI+GG+DIP+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHRLVEGRKLILGGVDIPYEKGLLGHSDADVLLHAIMDALLGAAALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTD ++K A S   L E  RL+++K YV+ N+D T+IAQ+PKL+P+ E +R N++  L
Sbjct: 62  PDTDERFKDADSMKLLSEVKRLLEQKLYVIENIDATVIAQRPKLAPYIEQMRENIANCL 120

[156][TOP]
>UniRef100_A8SMJ0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Parvimonas micra ATCC 33270 RepID=A8SMJ0_9FIRM
          Length = 157

 Score =  138 bits (348), Expect = 2e-31
 Identities = 68/122 (55%), Positives = 83/122 (68%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD+H L  G  LIIGG+ I H KG   HSD DVL+H + DAI+GALCL DIG+LF
Sbjct: 2   RIGFGFDVHELVVGRDLIIGGVKIEHEKGLLGHSDADVLVHAINDAIVGALCLGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD D K+K   S I  KE VRLM EKGY +GN+D  I AQKPKL+     +R N++ +L 
Sbjct: 62  PDNDSKYKDINSLIMTKEVVRLMKEKGYKIGNVDSVICAQKPKLADFIFKMRKNIANVLE 121

Query: 494 AD 499
            D
Sbjct: 122 TD 123

[157][TOP]
>UniRef100_A4VJV0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas stutzeri A1501 RepID=ISPF_PSEU5
          Length = 157

 Score =  138 bits (348), Expect = 2e-31
 Identities = 64/119 (53%), Positives = 87/119 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  EG  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFGEGDHITLGGVRIPHRFGLLAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDP++KGA S   L+  +  +  KGYV+GN+D TI+AQ PK++PH E +R  ++A L
Sbjct: 62  PDTDPQFKGADSRALLRHVLAQVQAKGYVVGNVDATIVAQAPKMAPHIERMRALIAADL 120

[158][TOP]
>UniRef100_UPI0001845378 hypothetical protein PROVRUST_01689 n=1 Tax=Providencia rustigianii
           DSM 4541 RepID=UPI0001845378
          Length = 170

 Score =  138 bits (347), Expect = 2e-31
 Identities = 63/116 (54%), Positives = 87/116 (75%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      ++IGG+ +P+ +G  AHSDGDV+LH +TDAILGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPIVIGGVRVPYEQGLIAHSDGDVVLHAITDAILGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S I L+EA   + +KGY++GN+D TI+AQ PK+ PH   +R N++
Sbjct: 62  PDTDPAYKGADSRILLREAFCQVRKKGYLIGNIDVTIMAQAPKMLPHIPQMRVNIA 117

[159][TOP]
>UniRef100_UPI000039A8BE COG0245: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae R2846 RepID=UPI000039A8BE
          Length = 158

 Score =  138 bits (347), Expect = 2e-31
 Identities = 67/122 (54%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA+ L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAVALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[160][TOP]
>UniRef100_A1WAK5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Acidovorax sp. JS42 RepID=A1WAK5_ACISJ
          Length = 167

 Score =  138 bits (347), Expect = 2e-31
 Identities = 63/129 (48%), Positives = 88/129 (68%)
 Frame = +2

Query: 107 AVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGAL 286
           A  A  + +R+G G+D+H L  G +L+IGG++IPHT G   HSD DVLLH +TDA+LGA 
Sbjct: 3   AANAMGMNFRIGEGWDVHALVPGRRLVIGGVEIPHTMGLLGHSDADVLLHAITDALLGAA 62

Query: 287 CLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENI 466
            L DIG  FPDTD ++KGA S   L+EA R + + GY +GN+D T++AQ P+L+ H   +
Sbjct: 63  ALGDIGSHFPDTDARFKGADSVALLEEAARRVGDTGYAIGNIDSTVVAQAPRLAAHIPAM 122

Query: 467 RNNLSAILG 493
           R  ++  LG
Sbjct: 123 RERIAGALG 131

[161][TOP]
>UniRef100_D0FVA6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Erwinia pyrifoliae RepID=D0FVA6_ERWPY
          Length = 157

 Score =  138 bits (347), Expect = 2e-31
 Identities = 68/120 (56%), Positives = 86/120 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       LIIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S   L+EA+R + +KGY +GN+D TIIAQ PK+ PH   +R N++  LG
Sbjct: 62  PDTDEAYKGADSRELLREALRQIAQKGYRVGNVDVTIIAQAPKMLPHAPQMRINIAEDLG 121

[162][TOP]
>UniRef100_C0AXD3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Proteus penneri ATCC 35198 RepID=C0AXD3_9ENTR
          Length = 161

 Score =  138 bits (347), Expect = 2e-31
 Identities = 65/116 (56%), Positives = 85/116 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+      +IIGG+ IP+ +G  AHSDGDV+LH VTDAILGA+ + DIG LF
Sbjct: 2   RIGHGYDVHKFGGEGPIIIGGVRIPYEQGLIAHSDGDVVLHAVTDAILGAVAMGDIGTLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S + L+EA   +  KGY +GNLD TIIAQ PK+ PH   +R N++
Sbjct: 62  PDTDPAYKGADSRVLLREAFSRVRAKGYRIGNLDVTIIAQAPKMLPHTPQMRVNIA 117

[163][TOP]
>UniRef100_B1R046 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Clostridium butyricum RepID=B1R046_CLOBU
          Length = 155

 Score =  138 bits (347), Expect = 2e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+H+L E  KLIIGG++IP  KG   HSD DVLLH + D++LGA  L DIG+ F
Sbjct: 2   RIGMGYDVHKLVEDRKLIIGGVEIPFEKGLLGHSDADVLLHAIMDSLLGACALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD K+KG  S   L+E  R++ E GY + N+D TIIAQKPK+SPH E +R N++  L 
Sbjct: 62  PDTDIKYKGISSINLLEETGRIIFENGYSINNIDATIIAQKPKMSPHIETMRKNIAKALN 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[164][TOP]
>UniRef100_A3XAR7 2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase/2C-methyl-D-erythritol
           2,4-cyclodiphosphate synthase n=1 Tax=Roseobacter sp.
           MED193 RepID=A3XAR7_9RHOB
          Length = 390

 Score =  138 bits (347), Expect = 2e-31
 Identities = 65/148 (43%), Positives = 96/148 (64%)
 Frame = +2

Query: 59  RVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSD 238
           R +   RAA ++ +   +   S   R+G+G+D+HR   G  +I+ G++IPH +  + HSD
Sbjct: 211 RPEDFARAAKILETEDKMSI-SPDIRLGNGYDVHRFGPGDSVILCGVEIPHDRSLQGHSD 269

Query: 239 GDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDC 418
            DV +H VTDAI GAL   DIGQ FP +DP+WKGA S+IFL+ A  L  E G+ + N+DC
Sbjct: 270 ADVGMHAVTDAIYGALAQGDIGQHFPPSDPQWKGAASEIFLRHAAELAREMGFQISNVDC 329

Query: 419 TIIAQKPKLSPHKENIRNNLSAILGADP 502
           T++ + PK+ P  E +R+ ++ ILG DP
Sbjct: 330 TLVCEYPKIGPRAEKMRSVMAEILGIDP 357

[165][TOP]
>UniRef100_A8FST1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella sediminis HAW-EB3 RepID=ISPF_SHESH
          Length = 161

 Score =  138 bits (347), Expect = 2e-31
 Identities = 65/116 (56%), Positives = 85/116 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+   G  L++GG+ IP+  G  AHSDGDV+LH ++DA+LGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGGGSPLLLGGVHIPYETGLIAHSDGDVVLHAISDAVLGAVALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTD ++KGA S   L+   RL  EKGY +GNLD TIIAQ PK++PH E IR  L+
Sbjct: 64  PDTDEEFKGADSRHLLRHCYRLAKEKGYSMGNLDVTIIAQAPKMAPHIEAIREVLA 119

[166][TOP]
>UniRef100_Q2SKW6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Hahella chejuensis KCTC 2396 RepID=ISPF_HAHCH
          Length = 163

 Score =  138 bits (347), Expect = 2e-31
 Identities = 62/119 (52%), Positives = 89/119 (74%), Gaps = 1/119 (0%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAE-GYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           +R+GHGFD+H  +E G  ++IGG++IPH +G +AHSDGDVLLH + DA+LGA    DIG+
Sbjct: 4   FRIGHGFDVHAFSETGDLIVIGGVNIPHERGLQAHSDGDVLLHAICDALLGAAAFGDIGK 63

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
            FPDTDP + GA S   L+  V  + +KGY +GN+D TI+AQ PK++PH E++R N+++
Sbjct: 64  HFPDTDPSFSGADSRNLLRSVVSKLHQKGYKIGNIDGTIVAQAPKMAPHIESMRVNIAS 122

[167][TOP]
>UniRef100_B2VFZ6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Erwinia tasmaniensis RepID=ISPF_ERWT9
          Length = 157

 Score =  138 bits (347), Expect = 2e-31
 Identities = 68/120 (56%), Positives = 86/120 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       LIIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S   L+EA+R + +KGY +GN+D TIIAQ PK+ PH   +R N++  LG
Sbjct: 62  PDTDEAYKGADSRELLREALRQIAQKGYRVGNVDVTIIAQAPKMLPHAPQMRINIAEDLG 121

[168][TOP]
>UniRef100_Q5WLT6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus clausii KSM-K16 RepID=ISPF_BACSK
          Length = 159

 Score =  138 bits (347), Expect = 2e-31
 Identities = 64/122 (52%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G GFD+H+L EG  L++GG+ IPH KG   HSD DVLLHT+TDA LGA+   D+G+ F
Sbjct: 3   RIGQGFDVHQLTEGRPLLLGGVHIPHPKGLLGHSDADVLLHTITDAALGAIGAGDLGKHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +K A S   L +A +L+   GY LGN+DCT++AQKPKL+P+ E +R  ++ +L 
Sbjct: 63  PDTDEAFKDADSKHLLSQAWQLVKNAGYTLGNVDCTVMAQKPKLAPYIEAMRKQIAELLE 122

Query: 494 AD 499
            D
Sbjct: 123 TD 124

[169][TOP]
>UniRef100_C1DSS0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Azotobacter vinelandii DJ RepID=ISPF_AZOVD
          Length = 157

 Score =  138 bits (347), Expect = 2e-31
 Identities = 63/116 (54%), Positives = 87/116 (75%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR AEG  + +GG+ IPH  G  AHSDGDVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFAEGDFVTLGGVRIPHRFGLLAHSDGDVLLHALCDALLGAAALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP++KG  S + L+  V L+ EKG+ +GN+D TI+AQ PK++PH E +R +++
Sbjct: 62  PDTDPRFKGVDSRVLLRHVVALVREKGWRVGNVDATIVAQAPKMAPHIERMRLSIA 117

[170][TOP]
>UniRef100_A2SG44 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Methylibium petroleiphilum PM1 RepID=A2SG44_METPP
          Length = 162

 Score =  137 bits (346), Expect = 3e-31
 Identities = 62/123 (50%), Positives = 87/123 (70%)
 Frame = +2

Query: 125 LPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIG 304
           +P+R+G G+D H L  G KL++GG+DIPH+ G   HSD D LLH +TDA+LGA  L DIG
Sbjct: 4   VPFRIGEGWDTHALVTGRKLVLGGVDIPHSHGLLGHSDADALLHAITDALLGAAALGDIG 63

Query: 305 QLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSA 484
           + FPDTD ++ GA S + L EA + + E G+V+GN+D TI+AQ PK++PH   +   ++A
Sbjct: 64  RHFPDTDARFAGADSGVLLAEAAKRVREAGWVVGNVDATIVAQAPKMAPHIPAMVERIAA 123

Query: 485 ILG 493
            LG
Sbjct: 124 CLG 126

[171][TOP]
>UniRef100_B4F226 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Proteus mirabilis RepID=ISPF_PROMH
          Length = 160

 Score =  137 bits (346), Expect = 3e-31
 Identities = 65/116 (56%), Positives = 85/116 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+      +IIGG+ IP+ +G  AHSDGDV+LH VTDAILGA+ + DIG LF
Sbjct: 2   RIGHGYDVHKFGGEGPIIIGGVRIPYEQGLLAHSDGDVVLHAVTDAILGAVAMGDIGTLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S + L+EA   +  KGY +GNLD TIIAQ PK+ PH   +R N++
Sbjct: 62  PDTDPAYKGADSRVLLREAFSRVMAKGYRIGNLDVTIIAQAPKMLPHTPQMRVNIA 117

[172][TOP]
>UniRef100_A7VAX1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium sp. L2-50 RepID=A7VAX1_9CLOT
          Length = 182

 Score =  137 bits (346), Expect = 3e-31
 Identities = 63/119 (52%), Positives = 90/119 (75%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L E  KLI+GG++IP+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLVEDRKLILGGVEIPYEKGLLGHSDADVLLHAIMDALLGAAALGDIGRHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTD ++KGA S + LK+  +L+DEK + + N+D T+IAQ+PKL+P+ E++R N++  L
Sbjct: 62  PDTDDRYKGADSMVLLKKVKKLLDEKFFFIENIDATVIAQQPKLAPYIEDMRKNIAECL 120

[173][TOP]
>UniRef100_A1JJT5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia enterocolitica subsp. enterocolitica 8081
           RepID=ISPF_YERE8
          Length = 162

 Score =  137 bits (346), Expect = 3e-31
 Identities = 70/118 (59%), Positives = 85/118 (72%), Gaps = 2/118 (1%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYK--LIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           R+GHGFD+H+  E     LIIGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+
Sbjct: 2   RIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGK 61

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           LFPDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R +L+
Sbjct: 62  LFPDTDPAFKGADSRALLREAYRRILAKGYRLGNLDITIIAQAPKMAPHIPQMRVHLA 119

[174][TOP]
>UniRef100_A8G9Z3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Serratia proteamaculans 568 RepID=ISPF_SERP5
          Length = 157

 Score =  137 bits (346), Expect = 3e-31
 Identities = 66/112 (58%), Positives = 82/112 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L+IGG+ IP+ KG  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPLVIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIR 469
           PDTDP +KGA S + L+EA + +  KGY LGNLD TIIAQ PK++PH   +R
Sbjct: 62  PDTDPAFKGADSRVLLREAWKRIRAKGYRLGNLDITIIAQAPKMAPHIPQMR 113

[175][TOP]
>UniRef100_Q65Q79 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Mannheimia succiniciproducens MBEL55E
           RepID=ISPF_MANSM
          Length = 159

 Score =  137 bits (346), Expect = 3e-31
 Identities = 65/112 (58%), Positives = 83/112 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDA+LGAL L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEARPLIIGGVEVPYHTGFIAHSDGDVALHALTDALLGALALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIR 469
           PDTD ++K   S I L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R
Sbjct: 63  PDTDMQFKNIDSRILLREAFRRVQEKGYKIGNVDVTIIAQAPKMRPHIDAMR 114

[176][TOP]
>UniRef100_Q8R6E7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium nucleatum subsp. nucleatum
           RepID=ISPF_FUSNN
          Length = 160

 Score =  137 bits (346), Expect = 3e-31
 Identities = 65/119 (54%), Positives = 87/119 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHKLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL
Sbjct: 63  PDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDSIIVMQKPKLRPYIDSIRDNIAKIL 121

[177][TOP]
>UniRef100_C9CXQ6 Bifunctional enzyme IspD/ispF n=1 Tax=Silicibacter sp. TrichCH4B
           RepID=C9CXQ6_9RHOB
          Length = 382

 Score =  137 bits (345), Expect = 4e-31
 Identities = 65/153 (42%), Positives = 97/153 (63%), Gaps = 1/153 (0%)
 Frame = +2

Query: 44  PKAFARVQRTCRAASVVASATAVKAPSLP-YRVGHGFDLHRLAEGYKLIIGGIDIPHTKG 220
           P+ FAR +   R++             +P  R+G+G+D+HR   G  +I+ GI +PH +G
Sbjct: 206 PEDFARAEHILRSSM----------DGIPDIRLGNGYDVHRFGPGDHVILCGIKVPHDRG 255

Query: 221 CEAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYV 400
            + HSD DV +H VTDA+ GA+   DIG+ FP +DP+WKGA S IFL+ AV L   KG+V
Sbjct: 256 LQGHSDADVGMHAVTDALYGAMAEGDIGRHFPPSDPQWKGAASKIFLRHAVDLARSKGFV 315

Query: 401 LGNLDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
           + N+DCT++ + PK+ PH E +R  ++ I+G D
Sbjct: 316 ISNVDCTLVCEFPKIGPHAETMRTQMAEIMGLD 348

[178][TOP]
>UniRef100_C4SWI6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Yersinia intermedia ATCC 29909 RepID=C4SWI6_YERIN
          Length = 160

 Score =  137 bits (345), Expect = 4e-31
 Identities = 68/116 (58%), Positives = 83/116 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LIIGG+ IP+  G  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 5   RIGHGFDVHKFGGAGPLIIGGVRIPYEMGLLAHSDGDVALHAATDALLGAAALGDIGKLF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S   L+EA R +  KGY LGNLD TIIAQ PK++PH   +R +L+
Sbjct: 65  PDTDPAFKGADSRALLREAYRRILAKGYRLGNLDITIIAQAPKMAPHIPQMRVHLA 120

[179][TOP]
>UniRef100_B6XG66 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Providencia alcalifaciens DSM 30120
           RepID=B6XG66_9ENTR
          Length = 170

 Score =  137 bits (345), Expect = 4e-31
 Identities = 63/116 (54%), Positives = 87/116 (75%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      ++IGG+ IP+ +G  AHSDGDV+LH +TDAILGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPIVIGGVRIPYEQGLIAHSDGDVVLHALTDAILGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP +KGA S + L+EA   + +KGY++GN+D TI+AQ PK+ PH   +R N++
Sbjct: 62  PDTDPAYKGADSRVLLREAFCQVRKKGYLIGNIDVTIMAQAPKMLPHIPQMRVNIA 117

[180][TOP]
>UniRef100_B5CL00 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ruminococcus lactaris ATCC 29176 RepID=B5CL00_9FIRM
          Length = 181

 Score =  137 bits (345), Expect = 4e-31
 Identities = 63/122 (51%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L E  KLI+GG++IP+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 2   RVGMGYDVHKLTEDRKLILGGVEIPYEKGLLGHSDADVLLHAIMDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD DP++KG  S   L+    L+DE GYV+ N+D TIIAQ+PK+ P+ + +R N++  LG
Sbjct: 62  PDIDPQYKGISSIKLLEHVAALLDENGYVVENIDATIIAQRPKMRPYIDQMRENIAKALG 121

Query: 494 AD 499
            +
Sbjct: 122 VE 123

[181][TOP]
>UniRef100_A4N0K3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae 22.1-21 RepID=A4N0K3_HAEIN
          Length = 158

 Score =  137 bits (345), Expect = 4e-31
 Identities = 67/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[182][TOP]
>UniRef100_A3TXL2 2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase/2C-methyl-D-erythritol
           2,4-cyclodiphosphate synthase n=1 Tax=Oceanicola
           batsensis HTCC2597 RepID=A3TXL2_9RHOB
          Length = 382

 Score =  137 bits (345), Expect = 4e-31
 Identities = 67/143 (46%), Positives = 96/143 (67%), Gaps = 2/143 (1%)
 Frame = +2

Query: 77  RAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLH 256
           RAA+++   T  K  ++  R+G+G+D+H   EG  + + G+ +PH +G   HSD DV +H
Sbjct: 211 RAAAIL---TGRKGTAMDVRLGNGYDVHAFCEGDGVTLCGVTVPHDRGLLGHSDADVGMH 267

Query: 257 TVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQK 436
            VTDAI GAL   DIG+ FP +DP+WKGA S IFLK AV+L  E+GY + N+DCT++ +K
Sbjct: 268 AVTDAIYGALAAGDIGRHFPPSDPQWKGADSRIFLKHAVKLAAERGYAVSNIDCTLVCEK 327

Query: 437 PKLSPHKENIRNNLSAI--LGAD 499
           PK+ PH   ++  L+ I  LGAD
Sbjct: 328 PKVGPHAAAMQARLAEITGLGAD 350

[183][TOP]
>UniRef100_B9RCH5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ricinus communis RepID=B9RCH5_RICCO
          Length = 230

 Score =  137 bits (345), Expect = 4e-31
 Identities = 65/87 (74%), Positives = 74/87 (85%)
 Frame = +2

Query: 242 DVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCT 421
           DVLLH V DAILGAL LPDIGQ+FPD+DPKWKGA S +F+KEAVRLM E GY +GNLD T
Sbjct: 71  DVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAPSSVFIKEAVRLMHEAGYDIGNLDAT 130

Query: 422 IIAQKPKLSPHKENIRNNLSAILGADP 502
           +I Q+PKLSPHKE IR+NL  +LGADP
Sbjct: 131 LILQRPKLSPHKEAIRSNLCELLGADP 157

[184][TOP]
>UniRef100_A9MF29 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Salmonella enterica subsp. arizonae serovar
           62:z4,z23:-- RepID=ISPF_SALAR
          Length = 159

 Score =  137 bits (345), Expect = 4e-31
 Identities = 68/120 (56%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY+LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYILGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[185][TOP]
>UniRef100_A5UE60 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=3
           Tax=Haemophilus influenzae RepID=ISPF_HAEIE
          Length = 158

 Score =  137 bits (345), Expect = 4e-31
 Identities = 67/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[186][TOP]
>UniRef100_B3EMU1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Chlorobium phaeobacteroides BS1 RepID=ISPF_CHLPB
          Length = 159

 Score =  137 bits (345), Expect = 4e-31
 Identities = 61/122 (50%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G D+H+ AEG KLI+GG++IPH+KG + HSD DVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGTGIDVHQFAEGRKLIVGGVEIPHSKGLKGHSDADVLLHAISDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDT P++K   S I L+   +L+ E+GY +GN+D  ++ +KPK++PH   +R N++A L 
Sbjct: 62  PDTSPQFKDIDSMILLQHVGKLIAEEGYAIGNIDSVLVMEKPKVAPHIMAMRGNIAACLD 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[187][TOP]
>UniRef100_A8MLB2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Alkaliphilus oremlandii OhILAs RepID=ISPF_ALKOO
          Length = 157

 Score =  137 bits (345), Expect = 4e-31
 Identities = 68/122 (55%), Positives = 85/122 (69%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L    KLIIGG+ IP+ KG   HSD DVLLH + DAILGA  L DIG+ F
Sbjct: 2   RVGIGYDVHKLVADRKLIIGGVHIPYEKGLLGHSDADVLLHAIKDAILGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S   LKE   L+  KGY + NLD TIIAQKPK++ H E +R N++A + 
Sbjct: 62  PDTDERYKGANSLELLKEVSNLIKSKGYKIHNLDATIIAQKPKMASHIEQMRANIAAAIN 121

Query: 494 AD 499
            D
Sbjct: 122 VD 123

[188][TOP]
>UniRef100_Q2G708 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Novosphingobium aromaticivorans DSM 12444
           RepID=ISPDF_NOVAD
          Length = 386

 Score =  137 bits (345), Expect = 4e-31
 Identities = 68/138 (49%), Positives = 89/138 (64%)
 Frame = +2

Query: 95  ASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAI 274
           AS    ++ S+  R G GFD+HRL EG +L + G++IPH KG   HSD DV +H + DA+
Sbjct: 218 ASDLEEQSMSVIPRTGMGFDVHRLVEGEELWLCGVNIPHGKGLSGHSDADVAIHALVDAL 277

Query: 275 LGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPH 454
           LGA+   DIG  FP +DP+WKGA SD FL  A  L+ E GY + N+D TII + PK+ PH
Sbjct: 278 LGAIAAGDIGDHFPPSDPQWKGASSDRFLAHAGTLVTEAGYRIANVDVTIICEAPKIGPH 337

Query: 455 KENIRNNLSAILGADPPL 508
           K  +R  L+ ILG D  L
Sbjct: 338 KAAMRETLARILGIDSAL 355

[189][TOP]
>UniRef100_D0CPU4 Bifunctional enzyme IspD/ispF n=1 Tax=Silicibacter lacuscaerulensis
           ITI-1157 RepID=D0CPU4_9RHOB
          Length = 376

 Score =  137 bits (344), Expect = 6e-31
 Identities = 65/152 (42%), Positives = 94/152 (61%)
 Frame = +2

Query: 44  PKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGC 223
           P+ FAR +R  R+              +  R+G+G+D+HR   G  +I+ G++IPH +G 
Sbjct: 204 PEDFARAERILRS-------------DMDVRLGNGYDVHRFGPGDHVILCGVEIPHDRGL 250

Query: 224 EAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVL 403
           + HSD DV +H VTDAI GAL   DIGQ FP +DP+WKGA S+IFL+ AV L    G+ +
Sbjct: 251 QGHSDADVGMHAVTDAIYGALAQGDIGQHFPPSDPQWKGAASEIFLRHAVDLATRMGFRI 310

Query: 404 GNLDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
            N+DCT+  + PK+ PH   +R  +S I+G +
Sbjct: 311 SNIDCTLACEYPKIGPHAAAMRQKMSEIMGLE 342

[190][TOP]
>UniRef100_C9Y696 Putative uncharacterized protein n=1 Tax=Curvibacter putative
           symbiont of Hydra magnipapillata RepID=C9Y696_9BURK
          Length = 159

 Score =  137 bits (344), Expect = 6e-31
 Identities = 64/122 (52%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D H+L EG KLI+GG++IPHTKG   HSD D LLH +TDA+LGA  L DIG+ F
Sbjct: 4   RIGEGWDTHQLVEGRKLILGGVEIPHTKGLLGHSDADALLHAITDALLGAAALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S + L +    +   GY + NLD T+IAQ PKL+PH + +R  ++ +L 
Sbjct: 64  PDTDPQYKGADSTVLLAKVAADVRALGYHIVNLDSTVIAQAPKLAPHIQAMRERVAFVLD 123

Query: 494 AD 499
            D
Sbjct: 124 LD 125

[191][TOP]
>UniRef100_B7WXL9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Comamonas testosteroni KF-1 RepID=B7WXL9_COMTE
          Length = 160

 Score =  137 bits (344), Expect = 6e-31
 Identities = 62/123 (50%), Positives = 87/123 (70%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G G+D+H L  G KLI+GG+++PH+ G   HSD DVLLH +TDA+ GA  L DIG+ 
Sbjct: 3   FRIGEGWDVHALVPGRKLILGGVEVPHSLGLLGHSDADVLLHAITDALFGAAALGDIGRH 62

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           F DTD ++KGA S + L EA R +  KG+ +GN+D TI+AQ PKL+PH E +R  ++ +L
Sbjct: 63  FSDTDAQFKGADSAVLLAEAARRVRAKGFEIGNIDSTIVAQAPKLAPHIEKMRERIAQVL 122

Query: 491 GAD 499
             D
Sbjct: 123 ELD 125

[192][TOP]
>UniRef100_B5J5A5 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative n=1
           Tax=Octadecabacter antarcticus 307 RepID=B5J5A5_9RHOB
          Length = 391

 Score =  137 bits (344), Expect = 6e-31
 Identities = 64/135 (47%), Positives = 88/135 (65%)
 Frame = +2

Query: 95  ASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAI 274
           A A  +    +  R G+GFD+HR   G  +++ G+ IPH++G + HSD DV +HTVTDAI
Sbjct: 220 ARAAKLLETRMDIRTGNGFDVHRFGAGDHVMLCGVKIPHSRGLQGHSDADVGMHTVTDAI 279

Query: 275 LGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPH 454
            GALC  DIGQ FP +DP+WKGA SDIFL  A  L  E G+ + ++DCT+I + PK+ P 
Sbjct: 280 YGALCRGDIGQHFPPSDPQWKGAASDIFLNHACALAREMGFEINHMDCTLICEFPKIGPV 339

Query: 455 KENIRNNLSAILGAD 499
              +R  ++ ILG D
Sbjct: 340 AAAMRTRMAQILGID 354

[193][TOP]
>UniRef100_A5TVR8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium nucleatum subsp. polymorphum ATCC
           10953 RepID=A5TVR8_FUSNP
          Length = 160

 Score =  137 bits (344), Expect = 6e-31
 Identities = 65/119 (54%), Positives = 87/119 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHKLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+ ++IR+N++ IL
Sbjct: 63  PDNDENLKDIDSAILLKKINDIMKEKNYKIVNLDSIIVIQKPKLRPYIDSIRDNIAKIL 121

[194][TOP]
>UniRef100_B8G1T9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Desulfitobacterium hafniense RepID=ISPF_DESHD
          Length = 158

 Score =  137 bits (344), Expect = 6e-31
 Identities = 63/122 (51%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H L  G  LI+ GIDIPH KG   HSD DVL HT+ DA+LGAL L D+G+ F
Sbjct: 3   RVGIGYDVHALVAGRPLILAGIDIPHEKGLLGHSDADVLTHTLMDALLGALALGDLGKHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD +++G  S   L++ ++L++E+GY +GN+DC I AQ+PKL+P+   +R NL+  L 
Sbjct: 63  PDTDERYRGISSMKLLEQVMKLLEERGYAIGNIDCIIAAQRPKLAPYIPQMRENLARALK 122

Query: 494 AD 499
            D
Sbjct: 123 TD 124

[195][TOP]
>UniRef100_Q1GGW9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Ruegeria sp. TM1040 RepID=ISPDF_SILST
          Length = 382

 Score =  137 bits (344), Expect = 6e-31
 Identities = 63/152 (41%), Positives = 97/152 (63%)
 Frame = +2

Query: 44  PKAFARVQRTCRAASVVASATAVKAPSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGC 223
           P+ F+R +   R+       T    P +  R+G+G+D+HR   G  +++ G+ +PH +G 
Sbjct: 206 PEDFSRAEHILRS-------TMDNIPDI--RLGNGYDVHRFGPGDHVMLCGVQVPHERGL 256

Query: 224 EAHSDGDVLLHTVTDAILGALCLPDIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVL 403
           + HSD DV +H VTDA+ GA+   DIG+ FP +DP+WKGA SDIFL+ AV L   KG+ +
Sbjct: 257 QGHSDADVGMHAVTDALYGAMAEGDIGRHFPPSDPQWKGAASDIFLRHAVELARSKGFTI 316

Query: 404 GNLDCTIIAQKPKLSPHKENIRNNLSAILGAD 499
            N+DCT++ + PK+ PH E +R  ++ I+G D
Sbjct: 317 NNVDCTLVCEYPKVGPHAEAMRARMAEIMGMD 348

[196][TOP]
>UniRef100_C6WWQ3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Methylotenera mobilis JLW8 RepID=C6WWQ3_METML
          Length = 157

 Score =  136 bits (343), Expect = 7e-31
 Identities = 63/122 (51%), Positives = 85/122 (69%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H L  G K IIGG+DIPH KG + HSD DVLLH + DA+LGA+ L DIG+ F
Sbjct: 2   RIGHGFDVHALVVGRKCIIGGVDIPHDKGLDGHSDADVLLHAICDALLGAVALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P TD ++KG  S   L+  V L+ E+GY +GN+D T++ + PKLSPH   +  +++A  G
Sbjct: 62  PPTDMRYKGIDSRQLLRHVVSLVRERGYTVGNIDATVMCEAPKLSPHTAAMCVHIAADCG 121

Query: 494 AD 499
            D
Sbjct: 122 VD 123

[197][TOP]
>UniRef100_Q0FAI8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/
           2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Rhodobacterales bacterium HTCC2255
           RepID=Q0FAI8_9RHOB
          Length = 389

 Score =  136 bits (343), Expect = 7e-31
 Identities = 62/122 (50%), Positives = 84/122 (68%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG+G+D+H L  G  + + GI+I HTK    HSD DV +H +TDAI GAL   DIGQ F
Sbjct: 234 RVGNGYDVHALGLGSSVTLNGIEISHTKALLGHSDADVAMHAITDAIFGALSAGDIGQWF 293

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P ++ KWK A S+IFL++AV L  E+G+++ +LDCTII + PK+ PH E +R N+S I  
Sbjct: 294 PPSEQKWKNASSEIFLRKAVLLCKERGFIINHLDCTIICETPKIGPHAEKMRENISEITK 353

Query: 494 AD 499
            D
Sbjct: 354 ID 355

[198][TOP]
>UniRef100_C7BLD3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Photorhabdus asymbiotica RepID=C7BLD3_9ENTR
          Length = 157

 Score =  136 bits (343), Expect = 7e-31
 Identities = 67/116 (57%), Positives = 82/116 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      +IIGG+ IP+ +G  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHKFGGEGPIIIGGVRIPYEQGLLAHSDGDVALHAATDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP  KG  S   L+EA R + EKGY +GNLD TIIAQ PK+ PH   +R NL+
Sbjct: 62  PDTDPTLKGVDSRKLLREAYRRIREKGYRIGNLDITIIAQAPKMLPHVPQMRVNLA 117

[199][TOP]
>UniRef100_C1PDI5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus coagulans 36D1 RepID=C1PDI5_BACCO
          Length = 158

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/123 (53%), Positives = 86/123 (69%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+HR  EG  L+IGG++IP+ KG   HSD DVLLH V DA LGA+   DIG+ 
Sbjct: 2   FRIGQGFDVHRFGEGRPLMIGGVEIPYEKGLLGHSDADVLLHAVADACLGAIGEGDIGRH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTD  +K A S   L    +L+ +KGY LGNLDCTIIAQKPK++P+   +R  ++ IL
Sbjct: 62  FPDTDAAFKDADSAALLAHVFQLVKQKGYKLGNLDCTIIAQKPKMAPYIGKMRETIARIL 121

Query: 491 GAD 499
            A+
Sbjct: 122 EAE 124

[200][TOP]
>UniRef100_C0CXI0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium asparagiforme DSM 15981
           RepID=C0CXI0_9CLOT
          Length = 185

 Score =  136 bits (343), Expect = 7e-31
 Identities = 64/123 (52%), Positives = 87/123 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+HRL E  +LI+GG++IP+ KG   HSD DVL+H V DA+LGA  L DIGQ F
Sbjct: 2   RIGQGYDVHRLVEERRLILGGVEIPYEKGLLGHSDADVLVHAVMDALLGAAALGDIGQHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KG  S   LK    L++EKGYV+ N+D TIIAQ+PKL+ ++  +  N++  L 
Sbjct: 62  PDTDPAYKGISSIELLKHVGALLEEKGYVVENIDATIIAQRPKLAAYRPQMAENIAEALH 121

Query: 494 ADP 502
            +P
Sbjct: 122 LEP 124

[201][TOP]
>UniRef100_B0PDS4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Anaerotruncus colihominis DSM 17241
           RepID=B0PDS4_9FIRM
          Length = 160

 Score =  136 bits (343), Expect = 7e-31
 Identities = 63/123 (51%), Positives = 84/123 (68%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D HR A+  +LIIGGI+IPHT+G + HSD DVL H V DA+LGAL L DIG LF
Sbjct: 4   RIGHGYDAHRFADNRRLIIGGIEIPHTRGLDGHSDADVLTHAVMDALLGALALGDIGSLF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD+DP + GA S   L     L+  +G+ +GN+D T+IAQ PK+ P+ E +R  ++   G
Sbjct: 64  PDSDPAYAGADSVALLVRVADLISVQGWRVGNIDATVIAQAPKIKPYIEQMRARIAKACG 123

Query: 494 ADP 502
             P
Sbjct: 124 VRP 126

[202][TOP]
>UniRef100_A4NP12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae PittHH RepID=A4NP12_HAEIN
          Length = 158

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  + 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[203][TOP]
>UniRef100_A4N762 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae R3021 RepID=A4N762_HAEIN
          Length = 158

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  + 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYEIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[204][TOP]
>UniRef100_Q31P19 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Synechococcus elongatus RepID=ISPF_SYNE7
          Length = 160

 Score =  136 bits (343), Expect = 7e-31
 Identities = 60/124 (48%), Positives = 88/124 (70%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G+G+D+HRL EG  LI+GGI + H+ G + HSD DVL H + DA+LGAL L DIG  
Sbjct: 4   FRIGNGYDIHRLVEGRPLILGGIQLEHSLGLDGHSDADVLTHAIMDALLGALSLGDIGHY 63

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FP TDP+WKGA S   L +  +L+ ++G+ +GNLD  ++A++PKL PH   +R+ L+ +L
Sbjct: 64  FPPTDPQWKGADSLKLLAQVNQLIRDRGWTIGNLDSVVVAEQPKLKPHIAAMRDRLAKVL 123

Query: 491 GADP 502
             +P
Sbjct: 124 ELEP 127

[205][TOP]
>UniRef100_Q086A7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella frigidimarina NCIMB 400 RepID=ISPF_SHEFN
          Length = 159

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      L++GG+ +P+  G  AHSDGDV+LH ++DAILGA+ L DIG+ F
Sbjct: 4   RIGHGFDVHKFGGDSPLVLGGVTVPYDSGLIAHSDGDVVLHAISDAILGAMALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  + GA S + LK   +L  +K +VLGNLD TIIAQ PK++PH E IR  LSA L 
Sbjct: 64  PDTDANFAGADSRVLLKHCYQLALQKQFVLGNLDVTIIAQAPKMAPHIEAIRQCLSADLQ 123

Query: 494 AD 499
            D
Sbjct: 124 TD 125

[206][TOP]
>UniRef100_B1JB32 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas putida W619 RepID=ISPF_PSEPW
          Length = 157

 Score =  136 bits (343), Expect = 7e-31
 Identities = 61/116 (52%), Positives = 86/116 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR  +G  + +GG+ IPH  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAGLGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTDP++KGA S + L+  V ++  KG+ +GN+D TI+AQ PK+SPH E +R  ++
Sbjct: 62  PDTDPQFKGADSRVLLRHVVGIVQAKGWKVGNVDATIVAQAPKMSPHIETMRQRIA 117

[207][TOP]
>UniRef100_B2RGP8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Porphyromonas gingivalis ATCC 33277 RepID=ISPF_PORG3
          Length = 162

 Score =  136 bits (343), Expect = 7e-31
 Identities = 61/121 (50%), Positives = 88/121 (72%)
 Frame = +2

Query: 128 PYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           P+R+G GFD+HRL+EGY L +GG+ + H+KG E HSD DVL+H + DA+LGA  L DIG 
Sbjct: 4   PFRIGFGFDVHRLSEGYPLWMGGVRLEHSKGLEGHSDADVLIHAICDALLGAAALRDIGY 63

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAI 487
            FP +DP++KG  S I L  A+ L+  +GY LGN+D TI A++PKL+PH  +++  L+ +
Sbjct: 64  HFPPSDPQYKGIDSKILLARAMELVRSQGYELGNIDATIAAEQPKLNPHIPDMQRVLAEV 123

Query: 488 L 490
           +
Sbjct: 124 I 124

[208][TOP]
>UniRef100_A5UHG0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=4
           Tax=Haemophilus influenzae RepID=ISPF_HAEIG
          Length = 158

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++  + 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[209][TOP]
>UniRef100_B0S2Q7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Finegoldia magna ATCC 29328 RepID=ISPF_FINM2
          Length = 159

 Score =  136 bits (343), Expect = 7e-31
 Identities = 61/116 (52%), Positives = 83/116 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G D+H+L E  KLI+GG++IPH KG   HSD DVL+H + DAI GALCL DIG+LF
Sbjct: 2   RIGFGLDVHKLVENRKLILGGVEIPHDKGLLGHSDADVLIHAIMDAICGALCLGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTD K+K   S + L++   +MD+ GY +GN+D TI  QKPKL  + + +R N++
Sbjct: 62  PDTDMKYKDIDSRVLLRKVFEIMDDMGYEIGNIDSTISCQKPKLRDYIDKMRENIA 117

[210][TOP]
>UniRef100_Q97LX0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Clostridium acetobutylicum RepID=ISPF_CLOAB
          Length = 155

 Score =  136 bits (343), Expect = 7e-31
 Identities = 66/122 (54%), Positives = 90/122 (73%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+L E  KLI+GG++I ++KG   HSD DVL+H + D+ILGA  L DIG+LF
Sbjct: 2   RVGIGYDVHKLVENRKLILGGVEIQYSKGLLGHSDADVLVHAIIDSILGAAGLGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PD+D K+KG  S   LKE   L+ +KGY +GN+D TIIAQKPK+SP+ E+I+ +L  +L 
Sbjct: 62  PDSDNKYKGISSLKLLKEVNALIKDKGYKIGNIDSTIIAQKPKISPYIEDIKKSLCNVLD 121

Query: 494 AD 499
            D
Sbjct: 122 ID 123

[211][TOP]
>UniRef100_A5P7M1 Bifunctional 2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase/2-C-methyl-D-erythritol
           2,4-cyclodiphosphate synthase protein n=1
           Tax=Erythrobacter sp. SD-21 RepID=A5P7M1_9SPHN
          Length = 380

 Score =  136 bits (342), Expect = 9e-31
 Identities = 63/124 (50%), Positives = 84/124 (67%)
 Frame = +2

Query: 128 PYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           P R+G GFD+H+LA G +L +GG+ I H KG   HSD DV LH + DA+LGA+   DIG 
Sbjct: 223 PVRIGSGFDVHKLAAGEELWLGGVKIDHDKGLAGHSDADVALHAIVDALLGAIGDGDIGS 282

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAI 487
            FP +DP+WKGA SD FL  A  L+ + GY  GN+D TII + PK+ PH+E +R  ++ +
Sbjct: 283 HFPPSDPQWKGASSDRFLAHAADLVAKAGYRTGNVDLTIICEAPKIGPHREAMRARIAEL 342

Query: 488 LGAD 499
           LG D
Sbjct: 343 LGVD 346

[212][TOP]
>UniRef100_Q8ZMF7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=7
           Tax=Salmonella enterica subsp. enterica RepID=ISPF_SALTY
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[213][TOP]
>UniRef100_Q57KJ5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Salmonella enterica RepID=ISPF_SALCH
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPRMRVFIAEDLG 121

[214][TOP]
>UniRef100_B5F410 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=16
           Tax=Salmonella enterica subsp. enterica RepID=ISPF_SALA4
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[215][TOP]
>UniRef100_Q165P5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Roseobacter denitrificans OCh 114 RepID=ISPF_ROSDO
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 61/120 (50%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+GFD+H    G  + + G+ IPH +G   HSD DV +HTVTDAI GAL + DIGQ F
Sbjct: 4   RLGNGFDVHAFGPGDHVTLCGVKIPHGQGLVGHSDADVAMHTVTDAIYGALAMGDIGQHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P +DP+WKGA SDIFLK AV    E+G+ + N+DCT+I + PK+ PH + +R  ++ I+G
Sbjct: 64  PPSDPQWKGAASDIFLKHAVAQASEQGFEINNVDCTLICEFPKIGPHAQAMREAMARIMG 123

[216][TOP]
>UniRef100_A6TD38 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Klebsiella pneumoniae RepID=ISPF_KLEP7
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[217][TOP]
>UniRef100_B5XV35 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Klebsiella pneumoniae 342 RepID=ISPF_KLEP3
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[218][TOP]
>UniRef100_B7MZ47 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=4
           Tax=Escherichia coli RepID=ISPF_ECO81
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[219][TOP]
>UniRef100_A7ZQJ0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=47
           Tax=Enterobacteriaceae RepID=ISPF_ECO24
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[220][TOP]
>UniRef100_A8ANW0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Citrobacter koseri ATCC BAA-895 RepID=ISPF_CITK8
          Length = 159

 Score =  136 bits (342), Expect = 9e-31
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYDKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[221][TOP]
>UniRef100_Q7P7A2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Fusobacterium nucleatum subsp. vincentii ATCC 49256
           RepID=Q7P7A2_FUSNV
          Length = 160

 Score =  135 bits (341), Expect = 1e-30
 Identities = 65/119 (54%), Positives = 85/119 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG KL++GG+++PHTKG   HSDGDVLLH +TDAI+GAL L DIG  F
Sbjct: 3   RIGNGYDVHKLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PD D   K   S I LK+   +M EK Y + NLD  I+ QKPKL P+   IR+N++ IL
Sbjct: 63  PDNDENLKDIDSAILLKKINDIMKEKNYKIVNLDSIIVIQKPKLRPYINGIRDNIAKIL 121

[222][TOP]
>UniRef100_C7QSM9 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Cyanothece sp. PCC 8802 RepID=C7QSM9_CYAP0
          Length = 159

 Score =  135 bits (341), Expect = 1e-30
 Identities = 62/122 (50%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+HRL EG  LI+GGI+IPHT G   HSD DVL H + DA+LGAL L DIG  F
Sbjct: 4   RIGNGYDIHRLVEGRPLILGGIEIPHTMGLLGHSDADVLTHAIMDAMLGALSLGDIGHYF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P +DP+WKGA S I L++  +L+   G+ +GN+D  IIA++PK+ PH + ++  L+  L 
Sbjct: 64  PPSDPQWKGANSLILLQQVNQLVRSHGWRIGNIDSVIIAERPKMKPHIKKMQEKLAETLQ 123

Query: 494 AD 499
            D
Sbjct: 124 ID 125

[223][TOP]
>UniRef100_C2HFH5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Finegoldia magna ATCC 53516 RepID=C2HFH5_PEPMA
          Length = 159

 Score =  135 bits (341), Expect = 1e-30
 Identities = 61/116 (52%), Positives = 83/116 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G D+H+L E  KLI+GG++IPH KG   HSD DVL+H + DAI GALCL DIG+LF
Sbjct: 2   RIGFGLDVHKLVEDRKLILGGVEIPHDKGLLGHSDADVLIHAIMDAICGALCLGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTD K+K   S + L++   +MD+ GY +GN+D TI  QKPKL  + + +R N++
Sbjct: 62  PDTDMKYKDIDSRVLLRKVFEIMDDMGYEVGNIDSTISCQKPKLRDYIDTMRENIA 117

[224][TOP]
>UniRef100_C2B9F2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Citrobacter youngae ATCC 29220 RepID=C2B9F2_9ENTR
          Length = 159

 Score =  135 bits (341), Expect = 1e-30
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGVGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[225][TOP]
>UniRef100_C1MAU4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Citrobacter sp. 30_2 RepID=C1MAU4_9ENTR
          Length = 168

 Score =  135 bits (341), Expect = 1e-30
 Identities = 68/120 (56%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 11  RIGHGFDVHAFGGVGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 70

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 71  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 130

[226][TOP]
>UniRef100_A4NCT5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae 3655 RepID=A4NCT5_HAEIN
          Length = 158

 Score =  135 bits (341), Expect = 1e-30
 Identities = 66/122 (54%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++K A S   L+EA R + +KGY +GN+D TIIAQ PK+ PH + +R  ++  L 
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQKKGYKIGNVDVTIIAQAPKMRPHIDAMRAKIAEDLQ 122

Query: 494 AD 499
            D
Sbjct: 123 CD 124

[227][TOP]
>UniRef100_Q4QMP5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Haemophilus influenzae 86-028NP RepID=ISPF_HAEI8
          Length = 158

 Score =  135 bits (341), Expect = 1e-30
 Identities = 65/116 (56%), Positives = 84/116 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H   E   LIIGG+++P+  G  AHSDGDV LH +TDAILGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           PDTD ++K A S   L+EA R + EKGY +GN+D TIIAQ PK+ PH + +R  ++
Sbjct: 63  PDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIA 118

[228][TOP]
>UniRef100_C5BGJ0 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Edwardsiella ictaluri 93-146 RepID=ISPF_EDWI9
          Length = 157

 Score =  135 bits (341), Expect = 1e-30
 Identities = 66/112 (58%), Positives = 80/112 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+HR      LIIGG+ I H +G  AHSDGDV LH  TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHRFGGEGPLIIGGVRIAHPQGLLAHSDGDVALHAATDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIR 469
           PDTDP +KGA S   L+EA R +  +GY LGNLD T+IAQ PK++PH   +R
Sbjct: 62  PDTDPAYKGADSRALLREAYRSIRARGYRLGNLDITLIAQAPKMAPHIPQMR 113

[229][TOP]
>UniRef100_Q0TEB2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=2
           Tax=Escherichia coli RepID=ISPF_ECOL5
          Length = 159

 Score =  135 bits (341), Expect = 1e-30
 Identities = 67/120 (55%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV+LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVVLHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ P++ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPRMLPHIPQMRVFIAEDLG 121

[230][TOP]
>UniRef100_B3QV82 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Chloroherpeton thalassium ATCC 35110
           RepID=ISPF_CHLT3
          Length = 157

 Score =  135 bits (341), Expect = 1e-30
 Identities = 61/122 (50%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G D+H+L EG KLIIGG++IP+ KG + HSD DVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGIGIDIHQLVEGRKLIIGGVEIPYEKGLKGHSDADVLLHAISDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KG  S + LK   +L++  GY   N+D  ++ +KPK++PH + +R N++A L 
Sbjct: 62  PDTDPAYKGIDSQLLLKHVRKLLETHGYKPVNVDSMLLLEKPKIAPHVQKMRENIAACLE 121

Query: 494 AD 499
            D
Sbjct: 122 VD 123

[231][TOP]
>UniRef100_B0CBC9 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Acaryochloris marina MBIC11017 RepID=ISPF_ACAM1
          Length = 161

 Score =  135 bits (341), Expect = 1e-30
 Identities = 60/125 (48%), Positives = 88/125 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG  LI+GG+ I H+ G + HSD DVL H + DA+LGAL L DIG  F
Sbjct: 5   RIGNGYDIHQLVEGRPLILGGVQIEHSLGLKGHSDADVLTHAIMDALLGALSLGDIGHYF 64

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P TDPKW GA S   L++  +L+ ++G+ +GN+D  ++A++PKL PH E +R+ +S +L 
Sbjct: 65  PPTDPKWAGADSLKLLEQVHQLILDRGWQIGNIDSVVVAERPKLKPHIEAMRDRISQVLN 124

Query: 494 ADPPL 508
             P L
Sbjct: 125 LSPEL 129

[232][TOP]
>UniRef100_Q2NAE1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Erythrobacter litoralis HTCC2594 RepID=ISPDF_ERYLH
          Length = 386

 Score =  135 bits (341), Expect = 1e-30
 Identities = 61/129 (47%), Positives = 86/129 (66%)
 Frame = +2

Query: 116 APSLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLP 295
           A  LP RVG GFD+H+L  G +L +GGI + H KG   HSD DV LH + DA+LGA+   
Sbjct: 221 ADLLPVRVGTGFDVHKLEAGEELWLGGIRLEHDKGLAGHSDADVALHAIVDALLGAIGKG 280

Query: 296 DIGQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNN 475
           DIG  FP +DP+WKGA S  F++ A +L+DE GY +GN+D TII + P++ PH++ +   
Sbjct: 281 DIGDHFPPSDPQWKGAASSAFIEHAAKLVDEAGYRVGNIDLTIICEAPRIGPHRDAMGQR 340

Query: 476 LSAILGADP 502
           ++ +L   P
Sbjct: 341 IAELLATSP 349

[233][TOP]
>UniRef100_UPI000196695E hypothetical protein SUBVAR_00601 n=1 Tax=Subdoligranulum variabile
           DSM 15176 RepID=UPI000196695E
          Length = 400

 Score =  135 bits (340), Expect = 2e-30
 Identities = 62/120 (51%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+H+L EG KLI+GG++IP+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 246 RIGHGYDVHQLVEGRKLILGGVEIPYEKGLLGHSDADVLLHAIMDAVLGAAALGDIGKHF 305

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S    +    L+ E+GY +GN+D TI+ Q PKL+PH   +R +++   G
Sbjct: 306 PDTDPAYKGADSLALTRAVAGLVREQGYSVGNIDSTILCQAPKLAPHIPAMRAHIAEAFG 365

[234][TOP]
>UniRef100_UPI0001694335 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Paenibacillus larvae subsp. larvae BRL-230010
           RepID=UPI0001694335
          Length = 146

 Score =  135 bits (340), Expect = 2e-30
 Identities = 68/122 (55%), Positives = 86/122 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG GFD+H+L EG K IIGG+++P+ KG   HSD DVLLH +TDAILGAL L DIG  F
Sbjct: 3   RVGQGFDVHQLVEGRKCIIGGVELPYEKGLLGHSDADVLLHAITDAILGALGLGDIGTHF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDT+ ++K A S + LK    L  EKGY LGN D TIIAQ+PK++PH   +   ++ +L 
Sbjct: 63  PDTEEEFKDANSLVLLKRVWGLAKEKGYRLGNADSTIIAQQPKMNPHIPAMVKIIAEVLE 122

Query: 494 AD 499
           AD
Sbjct: 123 AD 124

[235][TOP]
>UniRef100_B0MI73 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Anaerostipes caccae DSM 14662 RepID=B0MI73_9FIRM
          Length = 195

 Score =  135 bits (340), Expect = 2e-30
 Identities = 63/120 (52%), Positives = 89/120 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVG G+D+H+LAEG  LI+GG+ +P+ KG   HSD DVLLH + DA+LGA  L DIG+ F
Sbjct: 13  RVGMGYDVHKLAEGRPLILGGVHVPYEKGLLGHSDADVLLHAICDALLGAAALGDIGRHF 72

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S   LK+   L++++ Y++ N+D T+IAQKPKL+P+ E +R  ++  LG
Sbjct: 73  PDTDPEYKGADSMELLKKVRELVEKECYLIENVDATVIAQKPKLAPYIEEMREKIAETLG 132

[236][TOP]
>UniRef100_A3WC58 Bifunctional enzyme 2-C-methyl-D-erythritol
           4-phosphatecytidylyltransferase and
           2-C-methyl-D-erythritol n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WC58_9SPHN
          Length = 386

 Score =  135 bits (340), Expect = 2e-30
 Identities = 61/122 (50%), Positives = 85/122 (69%)
 Frame = +2

Query: 128 PYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQ 307
           P+R+G G+D+HRLAEG +L + G+ + HT G   HSD DV LH +TDA+LGA+   DIG 
Sbjct: 228 PFRIGQGYDVHRLAEGEELWLCGVKLEHTHGLAGHSDADVALHAITDAVLGAIGNGDIGT 287

Query: 308 LFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAI 487
            FP +D +W GARS  FL+ AV+L +E GY LGN+D T+I + PK+ PH+  +R  ++ I
Sbjct: 288 HFPPSDDQWAGARSGQFLEHAVKLAEEAGYALGNIDLTLICEAPKIGPHRPAMRAEVARI 347

Query: 488 LG 493
            G
Sbjct: 348 TG 349

[237][TOP]
>UniRef100_A3D792 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=3
           Tax=Shewanella baltica RepID=ISPF_SHEB5
          Length = 161

 Score =  135 bits (340), Expect = 2e-30
 Identities = 65/122 (53%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LI+ G+++P+  G  AHSDGDV+LH ++DAILGAL L DIG+ F
Sbjct: 4   RIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S + L+    L   KG+VLGNLD TIIAQ PK++PH E +R  L+A L 
Sbjct: 64  PDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLT 123

Query: 494 AD 499
           ++
Sbjct: 124 SE 125

[238][TOP]
>UniRef100_B8E8T4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Shewanella baltica OS223 RepID=ISPF_SHEB2
          Length = 161

 Score =  135 bits (340), Expect = 2e-30
 Identities = 65/122 (53%), Positives = 87/122 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H+      LI+ G+++P+  G  AHSDGDV+LH ++DAILGAL L DIG+ F
Sbjct: 4   RIGHGFDVHKFGAARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGALALGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD  +KGA S + L+    L   KG+VLGNLD TIIAQ PK++PH E +R  L+A L 
Sbjct: 64  PDTDAAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQVPKMAPHIEAMRQILAADLT 123

Query: 494 AD 499
           ++
Sbjct: 124 SE 125

[239][TOP]
>UniRef100_Q3KH86 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas fluorescens Pf0-1 RepID=ISPF_PSEPF
          Length = 157

 Score =  135 bits (340), Expect = 2e-30
 Identities = 64/119 (53%), Positives = 89/119 (74%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR AEG  + +GG+ I H  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTDP++KGA S + L+  V L+  KG+ +GN+D TI+AQ PK++PH E++R  ++A L
Sbjct: 62  PDTDPQFKGADSRVLLRHVVSLIHAKGWKVGNVDNTIVAQAPKMAPHIESMRALIAADL 120

[240][TOP]
>UniRef100_C1D559 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Laribacter hongkongensis HLHK9 RepID=ISPF_LARHH
          Length = 162

 Score =  135 bits (340), Expect = 2e-30
 Identities = 63/123 (51%), Positives = 89/123 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G G+D+HRL EG  L++GG+ IP  KG + HSD D L H +TDA+ GA  L DIG+ F
Sbjct: 4   RIGQGWDVHRLVEGRPLVLGGVTIPFDKGLDGHSDADALCHAITDALFGAAALGDIGRHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KGA S + L+EAVR + E G+ + N+D T+IAQ P+L+P+ E +R++L+A LG
Sbjct: 64  PDTDLEFKGADSRVLLREAVRRVREAGFDIVNVDSTVIAQAPRLAPYVEAMRSHLAADLG 123

Query: 494 ADP 502
             P
Sbjct: 124 LSP 126

[241][TOP]
>UniRef100_Q5QUC4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Idiomarina loihiensis RepID=ISPF_IDILO
          Length = 159

 Score =  135 bits (340), Expect = 2e-30
 Identities = 64/119 (53%), Positives = 86/119 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           RVGHG+D+HR      LI+GG++I H +G  AHSDGDV+LH VTDA+LGAL L DIGQ F
Sbjct: 4   RVGHGYDVHRWGSDKPLILGGVEIEHHQGLVAHSDGDVVLHAVTDAVLGALALGDIGQHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           PDTD ++ GA S   L  AV L  EK +  GN+D TI+AQ PK++PH +++R++++  L
Sbjct: 64  PDTDERYAGADSAELLSHAVSLCQEKEFKTGNIDVTIVAQAPKMAPHIDDMRSSIAQCL 122

[242][TOP]
>UniRef100_UPI0001AF3C65 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pseudomonas syringae pv. oryzae str. 1_6
           RepID=UPI0001AF3C65
          Length = 157

 Score =  135 bits (339), Expect = 2e-30
 Identities = 63/123 (51%), Positives = 89/123 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHG+D+HR AEG  + +GG+ I H  G  AHSDGDVLLH ++DA+LGA  L DIG+ F
Sbjct: 2   RIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP++KGA S + L+  ++ +  KG+ +GN+D TI+AQ PK++PH E +R  ++  L 
Sbjct: 62  PDTDPQFKGADSRVLLRHVLKQIHGKGWKVGNVDATIVAQAPKMAPHIEAMRALIAEDLQ 121

Query: 494 ADP 502
            DP
Sbjct: 122 VDP 124

[243][TOP]
>UniRef100_UPI000196AEE1 hypothetical protein CATMIT_00607 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196AEE1
          Length = 160

 Score =  135 bits (339), Expect = 2e-30
 Identities = 60/122 (49%), Positives = 89/122 (72%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G   D+H+L EG KLI+GG++IP+ KG + HSD DVLLH + ++I+GAL   DIG+ F
Sbjct: 4   RIGQSIDIHQLVEGRKLILGGVEIPYEKGLKGHSDADVLLHAIIESIIGALGEGDIGKHF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTD ++KG  S I L+E  +LM+EKGY +GN+D  I+ ++PK++PH   +R+N++  L 
Sbjct: 64  PDTDDRYKGISSMILLEETYKLMNEKGYKIGNVDAIIMTEQPKMAPHIPTMRHNIAEALH 123

Query: 494 AD 499
            D
Sbjct: 124 CD 125

[244][TOP]
>UniRef100_UPI0001850B2C 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Bacillus coahuilensis m4-4 RepID=UPI0001850B2C
          Length = 159

 Score =  135 bits (339), Expect = 2e-30
 Identities = 65/123 (52%), Positives = 85/123 (69%)
 Frame = +2

Query: 131 YRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQL 310
           +R+G GFD+H+L EG  LI+GGI IP+ KG   HSD DVLLH V DA LGA+   DIG  
Sbjct: 2   FRIGQGFDVHQLVEGRPLILGGITIPYEKGLLGHSDADVLLHVVADAALGAVAKGDIGHH 61

Query: 311 FPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAIL 490
           FPDTD  +K A S + L+    ++ E+GY L N+DCTIIAQKPK++P+   +R  ++ IL
Sbjct: 62  FPDTDAAFKDADSSVLLERVWEVVKEEGYELCNIDCTIIAQKPKMAPYVGQMRERIAQIL 121

Query: 491 GAD 499
            AD
Sbjct: 122 EAD 124

[245][TOP]
>UniRef100_UPI0001827255 hypothetical protein ENTCAN_04069 n=1 Tax=Enterobacter cancerogenus
           ATCC 35316 RepID=UPI0001827255
          Length = 159

 Score =  135 bits (339), Expect = 2e-30
 Identities = 67/120 (55%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ KG  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  +GY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQARGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[246][TOP]
>UniRef100_B7K7X5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Cyanothece sp. PCC 7424 RepID=B7K7X5_CYAP7
          Length = 159

 Score =  135 bits (339), Expect = 2e-30
 Identities = 59/123 (47%), Positives = 88/123 (71%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+G+G+D+H+L EG  LI+GG++IPHT G   HSD DVL H + DA+LGAL L DIG  F
Sbjct: 4   RIGNGYDIHKLVEGRPLILGGLEIPHTLGLLGHSDADVLTHAIMDAMLGALSLGDIGHYF 63

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           P +DP+W GA S + LK+  +L+ + G+ + N+D  I+A++PK+ PH + +++ LS  LG
Sbjct: 64  PPSDPQWAGANSLLLLKQVNQLIIDHGWKVSNIDSVIVAERPKIKPHIKGMQDKLSQTLG 123

Query: 494 ADP 502
            +P
Sbjct: 124 LNP 126

[247][TOP]
>UniRef100_A4G6C4 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Herminiimonas arsenicoxydans RepID=A4G6C4_HERAR
          Length = 168

 Score =  135 bits (339), Expect = 2e-30
 Identities = 63/124 (50%), Positives = 86/124 (69%)
 Frame = +2

Query: 122 SLPYRVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDI 301
           S+P+R+G G+D H L EG KLIIGG+ IPH  G   HSD DVLLH +TDA+ GA  L DI
Sbjct: 8   SMPFRIGQGYDCHALVEGRKLIIGGVTIPHVTGLLGHSDADVLLHAITDALFGAAALGDI 67

Query: 302 GQLFPDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLS 481
           G+ FPDT  ++ GA S + L+EA + +   G+ +GN+D TIIAQ+PK++PH   +  N++
Sbjct: 68  GRHFPDTAVEFAGADSRVLLREAAKRVAAAGFYIGNVDATIIAQRPKMAPHITQMIANVA 127

Query: 482 AILG 493
             LG
Sbjct: 128 EDLG 131

[248][TOP]
>UniRef100_C9XZ20 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Cronobacter turicensis RepID=C9XZ20_9ENTR
          Length = 160

 Score =  135 bits (339), Expect = 2e-30
 Identities = 66/120 (55%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +I+GG+ IP+ +G  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 3   RIGHGFDVHAFGGTGPIILGGVRIPYEQGLLAHSDGDVALHALTDALLGAAALGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK++PH   +R  ++  LG
Sbjct: 63  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMAPHIPQMRVFIAEDLG 122

[249][TOP]
>UniRef100_C8T268 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Klebsiella pneumoniae subsp. rhinoscleromatis ATCC
           13884 RepID=C8T268_KLEPR
          Length = 159

 Score =  135 bits (339), Expect = 2e-30
 Identities = 67/120 (55%), Positives = 84/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       +IIGG+ IP+ +G  AHSDGDV LH +TDA+LGA  L DIG+LF
Sbjct: 2   RIGHGFDVHAFGGEGPIIIGGVRIPYERGLLAHSDGDVALHALTDALLGAAALGDIGKLF 61

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R +  KGY LGN+D TIIAQ PK+ PH   +R  ++  LG
Sbjct: 62  PDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLG 121

[250][TOP]
>UniRef100_C8QFS4 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n=1
           Tax=Pantoea sp. At-9b RepID=C8QFS4_9ENTR
          Length = 161

 Score =  135 bits (339), Expect = 2e-30
 Identities = 65/120 (54%), Positives = 85/120 (70%)
 Frame = +2

Query: 134 RVGHGFDLHRLAEGYKLIIGGIDIPHTKGCEAHSDGDVLLHTVTDAILGALCLPDIGQLF 313
           R+GHGFD+H       L+IGG+ IP   G  AHSDGDV LH +TDA+LGA+ + DIG+LF
Sbjct: 3   RIGHGFDVHAFGGEGPLVIGGVRIPFEHGFIAHSDGDVALHALTDALLGAVAMGDIGKLF 62

Query: 314 PDTDPKWKGARSDIFLKEAVRLMDEKGYVLGNLDCTIIAQKPKLSPHKENIRNNLSAILG 493
           PDTDP +KGA S   L+EA R + +KGY +GN+D T+IAQ PK+ PH   +R N++  LG
Sbjct: 63  PDTDPAYKGADSRGLLREAWRRIQQKGYQVGNVDVTLIAQAPKMLPHVPQMRVNIAEDLG 122