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[1][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 346 bits (887), Expect = 6e-94
Identities = 167/173 (96%), Positives = 168/173 (97%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGI+LGVRMCRQLLASGE
Sbjct: 214 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGE 273
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWS RPK
Sbjct: 274 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSNRPK 333
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWGA 520
YVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRH GEARREKARA WGA
Sbjct: 334 AYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHSTGEARREKARAAWGA 386
[2][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 211 bits (538), Expect = 2e-53
Identities = 100/171 (58%), Positives = 126/171 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P E+ ALE IKDN+EAVKAYGI LG MC+++LA G
Sbjct: 220 GIMPINNYRGFLRMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V +H+YTLN+EKSA+AIL LG++D S++ R LPWR PA R E VRP+FW+ RPK
Sbjct: 279 VKSLHLYTLNMEKSALAILMNLGMIDESKISRSLPWRR-PANVFRTKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT+ W+ +P GRWG++RS +YGALSDHQF R AR +K + +W
Sbjct: 338 SYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSR----PRARDKKLQQEW 384
[3][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 211 bits (537), Expect = 2e-53
Identities = 101/173 (58%), Positives = 128/173 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+PAE++ ALE IKDN+EAV+AYGI LG MC+++LA G
Sbjct: 231 GIMPINNYKGFIRMAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHG- 289
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+AIL LGL++ S++ RPLPWR P R E VRP+FW+ RPK
Sbjct: 290 IKTLHLYTLNMEKSALAILMNLGLIEESKITRPLPWR-PPTNVFRVKEDVRPIFWANRPK 348
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWGA 520
Y+ RT WD YP GRWG++R+P+YGALSD+QFMR AR +K +W A
Sbjct: 349 SYLTRTIGWDQYPHGRWGDSRNPSYGALSDYQFMR----PRARGKKLLEEWAA 397
[4][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 211 bits (537), Expect = 2e-53
Identities = 98/166 (59%), Positives = 126/166 (75%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PAEI+ AL+ IKDN+EAVKAYGI LG MC+++LASG
Sbjct: 208 GIMPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASG- 266
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EK+A+AIL LGL++ S++ R LPWR P R E VRP+FW+ RPK
Sbjct: 267 IKTLHLYTLNMEKTALAILMNLGLIEESKLSRTLPWR-PPTNVFRVKEDVRPIFWANRPK 325
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREK 499
Y+ RT WD YP GRWG++R+P+YGAL+DHQF R G+ +E+
Sbjct: 326 SYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKLQEE 371
[5][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 211 bits (536), Expect = 3e-53
Identities = 99/171 (57%), Positives = 127/171 (74%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PAE++ ALE IKDN+EAV+AYGI LG MC++++A G
Sbjct: 235 GIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHG- 293
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+AIL LGL++ S++ RPLPWR P R E VRP+FW+ RPK
Sbjct: 294 IKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWR-PPTNVFRVKEGVRPIFWANRPK 352
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT W+ YP GRWG++ +P+YGALSDHQFMR AR +K +W
Sbjct: 353 SYISRTLGWEQYPQGRWGDSCNPSYGALSDHQFMR----PRARDKKLHDEW 399
[6][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 209 bits (531), Expect = 1e-52
Identities = 97/166 (58%), Positives = 125/166 (75%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PAEI+ ALE IKDN+EAVKAYGI LG MC+++LA+G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+ IL LGL++ S++ R LPWR P R E VRP+FW+ RPK
Sbjct: 279 IKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWR-PPTNVFRVKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREK 499
Y+ RT WD YP GRWG++R+P+YGAL+D+QF R G+ +E+
Sbjct: 338 SYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEE 383
[7][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 209 bits (531), Expect = 1e-52
Identities = 100/173 (57%), Positives = 128/173 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PAE++ ALE IKDN+EAV+AYGI LG MC+++LA G
Sbjct: 234 GIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHG- 292
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+AIL LGL++ S++ R LPWR P RA E VRP+FW+ RPK
Sbjct: 293 IKTLHLYTLNMEKSALAILMNLGLIEESKITRALPWR-PPTNVFRAKEDVRPIFWANRPK 351
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWGA 520
Y+ RT WD YP GRWG++ +P+YGALSD+QFMR AR +K +W +
Sbjct: 352 SYLSRTIGWDQYPHGRWGDSHNPSYGALSDYQFMR----PRARGKKLFEEWAS 400
[8][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 209 bits (531), Expect = 1e-52
Identities = 97/166 (58%), Positives = 125/166 (75%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PAEI+ ALE IKDN+EAVKAYGI LG MC+++LA+G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+ IL LGL++ S++ R LPWR P R E VRP+FW+ RPK
Sbjct: 279 IKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWR-PPTNVFRVKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREK 499
Y+ RT WD YP GRWG++R+P+YGAL+D+QF R G+ +E+
Sbjct: 338 SYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEE 383
[9][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 208 bits (530), Expect = 2e-52
Identities = 96/166 (57%), Positives = 125/166 (75%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P+EI+ AL+ IKDN+EAVK YGI LG MC+++LA+G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL++ S+V RPLPWR R E VRP+FW+ RPK
Sbjct: 279 IKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPA-TNVFRVKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREK 499
Y+KRT WD YP GRWG++R+P+YGAL+DHQF R G+ +E+
Sbjct: 338 SYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEE 383
[10][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 208 bits (529), Expect = 2e-52
Identities = 98/171 (57%), Positives = 124/171 (72%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMT CKTKVPAEI ALE IKDNDEAV+AYGI LG MC+++LA +
Sbjct: 220 GIMPIQNYKGFLRMTTLCKTKVPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAH-D 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+Y+LNLEKS + IL+ LGL+D SRV RPLPWR P + R E VRP+FW+ RP+
Sbjct: 279 IRTLHLYSLNLEKSVLGILQNLGLIDFSRVSRPLPWR-PPTNSKRTKEDVRPIFWANRPR 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT WD +P GRWG+T +PAYG+ SDHQF R+ + R +K + +W
Sbjct: 338 SYISRTTSWDDFPRGRWGDTANPAYGSFSDHQFTRK----KTRSKKLQKEW 384
[11][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 207 bits (527), Expect = 3e-52
Identities = 95/166 (57%), Positives = 125/166 (75%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P+EI+ AL+ IKDN+EAV+ YGI LG MC+++LA+G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL++ S+V RPLPWR R E VRP+FW+ RPK
Sbjct: 279 IKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPA-TNVFRVKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREK 499
Y+KRT WD YP GRWG++R+P+YGAL+DHQF R G+ +E+
Sbjct: 338 SYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEE 383
[12][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 207 bits (526), Expect = 5e-52
Identities = 97/171 (56%), Positives = 125/171 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P+E++ ALE IKDNDEAVKAYGI LG MC+++LA G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ VH+YTLN+EKSA+AIL LGL++ S++ RP PWR P R E VRP+FW+ RP+
Sbjct: 279 IKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRR-PTNVFRVKEDVRPIFWANRPR 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT WD YP GRW ++ +P+YG L+D+QFMR AR +K + +W
Sbjct: 338 SYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMR----PRARDKKLQDEW 384
[13][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 207 bits (526), Expect = 5e-52
Identities = 97/171 (56%), Positives = 125/171 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P+E++ ALE IKDNDEAVKAYGI LG MC+++LA G
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ VH+YTLN+EKSA+AIL LGL++ S++ RP PWR P R E VRP+FW+ RP+
Sbjct: 279 IKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRR-PTNVFRVKEDVRPIFWANRPR 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT WD YP GRW ++ +P+YG L+D+QFMR AR +K + +W
Sbjct: 338 SYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMR----PRARDKKLQDEW 384
[14][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 206 bits (525), Expect = 6e-52
Identities = 96/171 (56%), Positives = 124/171 (72%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMT CKTKVPAEI LE IKDNDEAV+AYGI LG MC+++LA +
Sbjct: 220 GIMPIQNYKGFLRMTSLCKTKVPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAH-D 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+Y+LNLEKS + IL+ LGL+D S+V RPLPWR P + R E VRP+FW+ RP+
Sbjct: 279 IRTLHLYSLNLEKSVLGILQNLGLIDFSKVTRPLPWR-PPTNSKRTKEDVRPIFWANRPR 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT WD +P GRWG+T +PAYG+ SDHQF+R+ + R +K + +W
Sbjct: 338 SYISRTTSWDEFPRGRWGDTGNPAYGSFSDHQFLRK----KTRSKKLQKEW 384
[15][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 205 bits (521), Expect = 2e-51
Identities = 95/171 (55%), Positives = 126/171 (73%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+P+EI+ ALE IKDN+EAV+AYGI LG MC+++LA G
Sbjct: 220 GIMPINNYKGFIRMAGFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN+EKSA+ IL LGL+D ++++RPLPWR R E VRP+FW+ RP+
Sbjct: 279 IKTLHLYTLNMEKSALGILANLGLIDMTKIRRPLPWRPA-TNVLRTKENVRPIFWANRPR 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT W+ +P GRWG+ RSPAYGAL+D+QF+RR +R +K +W
Sbjct: 338 SYISRTIGWEQFPNGRWGDARSPAYGALNDYQFLRR----RSRSKKILEEW 384
[16][TOP]
>UniRef100_Q3EAG8 Methylenetetrahydrofolate reductase n=1 Tax=Arabidopsis thaliana
RepID=Q3EAG8_ARATH
Length = 407
Score = 199 bits (505), Expect = 1e-49
Identities = 93/171 (54%), Positives = 121/171 (70%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+PAE++ ALE IKDNDEAVKAYGI MC+++LA G
Sbjct: 220 GIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL+D S++ R LPWR PA R E VRP+FW+ RPK
Sbjct: 279 ITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRR-PANVFRTKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT+ W+ +P GRWG++ S AY LSD+QF R + R +K + +W
Sbjct: 338 SYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFAR----PKGRDKKLQQEW 384
[17][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 199 bits (505), Expect = 1e-49
Identities = 93/171 (54%), Positives = 121/171 (70%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+PAE++ ALE IKDNDEAVKAYGI MC+++LA G
Sbjct: 30 GIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG- 88
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL+D S++ R LPWR PA R E VRP+FW+ RPK
Sbjct: 89 ITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRR-PANVFRTKEDVRPIFWANRPK 147
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT+ W+ +P GRWG++ S AY LSD+QF R + R +K + +W
Sbjct: 148 SYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFAR----PKGRDKKLQQEW 194
[18][TOP]
>UniRef100_Q9SE60-2 Isoform 2 of Methylenetetrahydrofolate reductase 1 n=1
Tax=Arabidopsis thaliana RepID=Q9SE60-2
Length = 421
Score = 199 bits (505), Expect = 1e-49
Identities = 93/171 (54%), Positives = 121/171 (70%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+PAE++ ALE IKDNDEAVKAYGI MC+++LA G
Sbjct: 220 GIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL+D S++ R LPWR PA R E VRP+FW+ RPK
Sbjct: 279 ITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRR-PANVFRTKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT+ W+ +P GRWG++ S AY LSD+QF R + R +K + +W
Sbjct: 338 SYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFAR----PKGRDKKLQQEW 384
[19][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 199 bits (505), Expect = 1e-49
Identities = 93/171 (54%), Positives = 121/171 (70%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RM GFCKTK+PAE++ ALE IKDNDEAVKAYGI MC+++LA G
Sbjct: 220 GIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHG- 278
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H+YTLN++KSA+ IL LGL+D S++ R LPWR PA R E VRP+FW+ RPK
Sbjct: 279 ITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRR-PANVFRTKEDVRPIFWANRPK 337
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT+ W+ +P GRWG++ S AY LSD+QF R + R +K + +W
Sbjct: 338 SYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFAR----PKGRDKKLQQEW 384
[20][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 177 bits (448), Expect = 5e-43
Identities = 85/171 (49%), Positives = 114/171 (66%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+P+E++ ALE IKDNDEAVKAYGI LG MC+++LA
Sbjct: 220 GIMPINNYKGFLRMTGFCKTKIPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAH-- 277
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
G+ + L ++ + LGL++ S++ RP PWR P R E VRP+FW+ RP+
Sbjct: 278 --GIKTFGLTMDLP----WQNLGLIEESKISRPFPWRR-PTNVFRVKEDVRPIFWANRPR 330
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADW 514
Y+ RT WD YP GRW ++ +P+YG L+D+QFMR AR +K + +W
Sbjct: 331 SYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQFMR----PRARDKKLQDEW 377
[21][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 171 bits (433), Expect = 3e-41
Identities = 85/172 (49%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI+ LE IKDND A++ YGI+L V MCR LL SG+
Sbjct: 259 GIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGK 318
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L QLGL T +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 319 VPGLHFYTLNREVATMEVLRQLGLW-TEDPRRPLPWA-VSAHPKRKVEDVRPIFWASRPK 376
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L+D+ + ++ +E WG
Sbjct: 377 SYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF--YLKSKSSKEALLQMWG 426
[22][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 170 bits (431), Expect = 5e-41
Identities = 83/172 (48%), Positives = 112/172 (65%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIEL VR+CR+LL SG
Sbjct: 254 GIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGL 313
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 314 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 371
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 372 SYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 421
[23][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 169 bits (428), Expect = 1e-40
Identities = 84/173 (48%), Positives = 113/173 (65%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K ++P EI+ +E IKDND A++ YGI+L V+MCR LL SG+
Sbjct: 259 GIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGK 318
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + + +L QLGL ++ R RPLPW V A R VE VRP+FWS RP
Sbjct: 319 VPGLHFYTLNREVATMEVLRQLGLWIEDPR--RPLPWA-VSAHPKRKVEDVRPIFWSSRP 375
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQDWD +P GRWGN+ SPA+G L+D+ + ++ +E WG
Sbjct: 376 KSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF--YLKSKSSKEALLQMWG 426
[24][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 169 bits (428), Expect = 1e-40
Identities = 84/173 (48%), Positives = 113/173 (65%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K ++P EI+ +E IKDND A++ YGI+L V+MCR LL SG+
Sbjct: 259 GIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRNYGIQLAVQMCRVLLDSGK 318
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + + +L QLGL ++ R RPLPW V A R VE VRP+FWS RP
Sbjct: 319 VPGLHFYTLNREVATMEVLRQLGLWIEDPR--RPLPWA-VSAHPKRKVEDVRPIFWSSRP 375
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQDWD +P GRWGN+ SPA+G L+D+ + ++ +E WG
Sbjct: 376 KSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF--YLKSKSSKEALLQMWG 426
[25][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 168 bits (425), Expect = 2e-40
Identities = 82/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI YG +++ K +VP EI D +E IKDND A++ YGI+L V MCR+LL SG
Sbjct: 249 GIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGL 308
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + + +L++LG+ +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 309 VHGLHFYTLNREVATIDVLKRLGMWKED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 366
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 367 SYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 416
[26][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 168 bits (425), Expect = 2e-40
Identities = 82/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI YG +++ K +VP EI D +E IKDND A++ YGI+L V MCR+LL SG
Sbjct: 249 GIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGL 308
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + + +L++LG+ +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 309 VHGLHFYTLNREVATIDVLKRLGMWKED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 366
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 367 SYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 416
[27][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 168 bits (425), Expect = 2e-40
Identities = 82/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIEL V +CR+LL SG
Sbjct: 295 GIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGL 354
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 355 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 412
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 413 SYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 462
[28][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 168 bits (425), Expect = 2e-40
Identities = 82/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIEL V +CR+LL SG
Sbjct: 295 GIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGL 354
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 355 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 412
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 413 SYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 462
[29][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 168 bits (425), Expect = 2e-40
Identities = 82/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIEL V +CR+LL SG
Sbjct: 295 GIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGL 354
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 355 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 412
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 413 SYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 462
[30][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 167 bits (422), Expect = 5e-40
Identities = 82/172 (47%), Positives = 110/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YG+EL V MCR+LL SG
Sbjct: 257 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGM 316
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + +L++LGL + +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 317 VHGLHFYTLNREVATTEVLKRLGLWNED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 374
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 375 SYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 424
[31][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 167 bits (422), Expect = 5e-40
Identities = 79/151 (52%), Positives = 104/151 (68%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V MC++LLASG
Sbjct: 249 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGL 308
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L++LG+ + +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 309 VPGLHFYTLNREVATMEVLKRLGMWNED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 366
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RTQ WD +P GRWGN+ SPA+G L D+
Sbjct: 367 SYIYRTQAWDEFPNGRWGNSSSPAFGELKDY 397
[32][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 166 bits (420), Expect = 9e-40
Identities = 80/172 (46%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C++LLASG
Sbjct: 278 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGL 337
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 338 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 395
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 396 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 445
[33][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 166 bits (420), Expect = 9e-40
Identities = 80/172 (46%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C++LLASG
Sbjct: 296 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGL 355
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 356 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 413
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 414 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 463
[34][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 166 bits (420), Expect = 9e-40
Identities = 82/172 (47%), Positives = 109/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP I D +E IKDND A++ YGIEL V +CR+LL SG
Sbjct: 260 GIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGL 319
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW V A R E VRP+FW+ RPK
Sbjct: 320 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-VSAHPKRREEDVRPIFWASRPK 377
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 378 SYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 427
[35][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 166 bits (420), Expect = 9e-40
Identities = 82/172 (47%), Positives = 109/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP I D +E IKDND A++ YGIEL V +CR+LL SG
Sbjct: 295 GIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGL 354
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + + +L+QLG+ T +RPLPW V A R E VRP+FW+ RPK
Sbjct: 355 VPGLHFYTLNREVATMEVLKQLGMW-TEDPRRPLPWA-VSAHPKRREEDVRPIFWASRPK 412
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 413 SYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 462
[36][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 166 bits (420), Expect = 9e-40
Identities = 80/172 (46%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI YG +++ K +VP EI D +E IKDND A++ YGI+L V MCR+LL SG
Sbjct: 249 GIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMCRELLDSGL 308
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + + +L++LG+ +RP+PW + A R VE VRP+FW+ RPK
Sbjct: 309 VHGLHFYTLNREVATIDVLKRLGMWKED-PRRPMPWA-MSAHPKRRVEDVRPIFWASRPK 366
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 367 SYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 416
[37][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 166 bits (420), Expect = 9e-40
Identities = 80/172 (46%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C++LLASG
Sbjct: 255 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGL 314
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 315 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 372
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 373 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 422
[38][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 166 bits (420), Expect = 9e-40
Identities = 80/172 (46%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C++LLASG
Sbjct: 285 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGL 344
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 345 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 402
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 403 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 452
[39][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 166 bits (419), Expect = 1e-39
Identities = 81/172 (47%), Positives = 109/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C +LLASG
Sbjct: 278 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGL 337
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 338 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 395
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE WG
Sbjct: 396 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPRELLLKMWG 445
[40][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 166 bits (419), Expect = 1e-39
Identities = 81/172 (47%), Positives = 109/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C +LLASG
Sbjct: 296 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGL 355
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 356 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 413
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE WG
Sbjct: 414 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPRELLLKMWG 463
[41][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 165 bits (417), Expect = 2e-39
Identities = 81/172 (47%), Positives = 112/172 (65%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YG+EL V MCR+LL SG
Sbjct: 113 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGL 172
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + +L++LG+ + +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 173 VHGLHFYTLNREVATTEVLKRLGIWNED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 230
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ ++ ++ + RE+ WG
Sbjct: 231 SYIYRTQEWDDFPNGRWGNSSSPAFGELKDY-YLFYLKSKPSPREELLKMWG 281
[42][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 165 bits (417), Expect = 2e-39
Identities = 80/173 (46%), Positives = 113/173 (65%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIE V +C++LLASG
Sbjct: 254 GIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGL 313
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + + +L++LGL ++ R RPLPW + A R VE VRP+FW+ RP
Sbjct: 314 VPGLHFYTLNREVATIEVLKRLGLWIEDPR--RPLPWA-LSAHPKRRVEDVRPIFWASRP 370
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 371 KSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 421
[43][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 165 bits (417), Expect = 2e-39
Identities = 81/172 (47%), Positives = 108/172 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI +E IKDND A++ YGI+ V MC+ LLASGE
Sbjct: 255 GIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGE 314
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + + +L QLGL +RPLPW + A R VE VRP+FW+ RPK
Sbjct: 315 VSGLHFYTLNREVATMEVLRQLGLW-AEDPRRPLPWA-ISAHPKRKVEDVRPIFWASRPK 372
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L+D+ + ++ +E WG
Sbjct: 373 SYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLF--YLKSKSPKEALLQMWG 422
[44][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 165 bits (417), Expect = 2e-39
Identities = 80/173 (46%), Positives = 113/173 (65%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIE V +C++LLASG
Sbjct: 254 GIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGL 313
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + + +L++LGL ++ R RPLPW + A R VE VRP+FW+ RP
Sbjct: 314 VPGLHFYTLNREVATIEVLKRLGLWIEDPR--RPLPWA-LSAHPKRRVEDVRPIFWASRP 370
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 371 KSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 421
[45][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 164 bits (416), Expect = 3e-39
Identities = 81/172 (47%), Positives = 109/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGIEL V +C +LLASG
Sbjct: 255 GIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGL 314
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H YTLN E + +L++LG+ T +RPLPW + A R E VRP+FW+ RPK
Sbjct: 315 VPGLHFYTLNREMATTEVLKRLGMW-TEDPRRPLPWA-LSAHPKRREEDVRPIFWASRPK 372
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE WG
Sbjct: 373 SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPRELLLKMWG 422
[46][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 164 bits (415), Expect = 3e-39
Identities = 82/172 (47%), Positives = 110/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI+ +E IKDND A++ YGIEL V MCR+LL SG
Sbjct: 252 GIFPIQGYHSLRQLVKLSKLEVPQEITAVIEPIKDNDAAIRNYGIELAVTMCRELLVSGV 311
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + V +L++LG+ + +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 312 VSGLHFYTLNREVATVEVLKRLGIWNED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 369
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQDWD +P GRWGN+ SPA+G L ++ ++ RE+ WG
Sbjct: 370 SYIYRTQDWDEFPNGRWGNSSSPAFGELKNYYLF--CLKSKSPREELLKMWG 419
[47][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 164 bits (415), Expect = 3e-39
Identities = 81/172 (47%), Positives = 111/172 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YG+EL V MCR+LL SG
Sbjct: 245 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGL 304
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + +L++LG+ + +RPLPW V A R VE VRP+FW+ RPK
Sbjct: 305 VHGLHFYTLNREVATTEVLKRLGIWNED-PRRPLPWA-VSAHPKRRVEDVRPIFWASRPK 362
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
Y+ RTQ+WD +P GRWGN+ SPA+G L D+ ++ ++ RE+ WG
Sbjct: 363 SYIYRTQEWDDFPNGRWGNSSSPAFGELKDY-YLFYLKSSLPPREELLKMWG 413
[48][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 163 bits (413), Expect = 6e-39
Identities = 83/173 (47%), Positives = 106/173 (61%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI T ++T K +P EI +E IKDND A++ YGI+L MCR LL SG+
Sbjct: 227 GIFPIQTNRSLVQLTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGK 286
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+HMYTLNLE + + IL+ LGL V +PLPW+ R E VRP+FW RPK
Sbjct: 287 VHGLHMYTLNLETATIQILKNLGLW-CQDVAKPLPWKTSANPERRENETVRPIFWCDRPK 345
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSD-HQFMRRHRNGEARREKARADWG 517
Y+ RTQ WD +P GRWG++ SPA+G L D H F R R ++K R+ WG
Sbjct: 346 SYIHRTQGWDEFPNGRWGDSASPAFGELKDYHLFFLRSRTA---KDKLRSLWG 395
[49][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 163 bits (412), Expect = 7e-39
Identities = 79/173 (45%), Positives = 109/173 (63%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI Y ++ K +VP I D LE IK++DEA++ YG++L V MCR+LL+S +
Sbjct: 232 GVMPIQAYASLLQLVKLSKLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDD 291
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H+YTLN E + +L+QLGL + R LPW+ A R E VRP+FWS RPK
Sbjct: 292 VPGIHVYTLNREVATTELLQQLGLWRPYQSHRLLPWK-PSANLKRLQEDVRPIFWSSRPK 350
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQ-FMRRHRNGEARREKARADWG 517
Y+ RT +WD +P GRWGN+ +P++ LSDH F + + E R K WG
Sbjct: 351 SYIHRTSNWDEFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKM---WG 400
[50][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 162 bits (411), Expect = 1e-38
Identities = 83/151 (54%), Positives = 100/151 (66%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY GF RMT KTKVP I D LE IKDNDE VK YG+ L V M ++LL G
Sbjct: 213 GIMPIQTYAGFVRMTTLSKTKVPQYIMDNLEPIKDNDEEVKKYGVRLCVEMSKRLLDFG- 271
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLNLE+S +L+ L LV ++ LPW AG R E+VRP+FW RP+
Sbjct: 272 VEGLHFYTLNLERSVRKVLKGLQLVTPDQLSPFLPWAQSAAGN-RLKEEVRPIFWQNRPR 330
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RT WD +P GRWG+ RSPA+G LSD+
Sbjct: 331 SYIARTGSWDEFPNGRWGDYRSPAFGDLSDY 361
[51][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 162 bits (409), Expect = 2e-38
Identities = 79/173 (45%), Positives = 110/173 (63%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIE V +C++LL SG
Sbjct: 380 GIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGL 439
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + +L++LG+ ++ R RPLPW V A R E VRP+FW+ RP
Sbjct: 440 VPGLHFYTLNREMATTEVLKRLGMWIEDPR--RPLPWA-VSAHPKRREEDVRPIFWASRP 496
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 497 KSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 547
[52][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 162 bits (409), Expect = 2e-38
Identities = 79/173 (45%), Positives = 110/173 (63%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP +I D +E IKDND A++ YGIE V +C++LL SG
Sbjct: 296 GIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGL 355
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + +L++LG+ ++ R RPLPW V A R E VRP+FW+ RP
Sbjct: 356 VPGLHFYTLNREMATTEVLKRLGMWIEDPR--RPLPWA-VSAHPKRREEDVRPIFWASRP 412
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ RE+ WG
Sbjct: 413 KSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPREELLKMWG 463
[53][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 161 bits (408), Expect = 2e-38
Identities = 80/173 (46%), Positives = 111/173 (64%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YGI+ V +C+QLLASG
Sbjct: 254 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGL 313
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL-VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
VPG+H YTLN E + +L++LG+ V+ R RPLPW + A R E VRP+FW+ RP
Sbjct: 314 VPGLHFYTLNREVATTEVLKRLGMWVEDPR--RPLPWA-LSAHPKRREEDVRPIFWATRP 370
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K Y+ RTQ+WD +P GRWGN+ SPA+G L D+ + ++ +E+ WG
Sbjct: 371 KSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF--YLKSKSPKEELLKMWG 421
[54][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 161 bits (407), Expect = 3e-38
Identities = 78/172 (45%), Positives = 110/172 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI Y + + K ++P EI +A+E I+DNDEA++ YG+ V M R+L SG
Sbjct: 244 GVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFDSGL 303
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
V G+H YTLN E + + IL+Q+GL T +QRP PW+ A R E+VRP+FW+ RPK
Sbjct: 304 VNGLHFYTLNREVATIQILKQIGLW-TEDIQRPWPWKRT-ANYNRCEEEVRPIFWASRPK 361
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
YV RTQ+WD +P GRWG++ SPA+G L+D+ N A++E+ WG
Sbjct: 362 SYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPN--AKKEELLDMWG 411
[55][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 160 bits (405), Expect = 5e-38
Identities = 85/160 (53%), Positives = 102/160 (63%), Gaps = 10/160 (6%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLAS-- 175
GIMPI +Y F RMT +C VP EI LE IKD+DEAVK G L MCRQ+LA
Sbjct: 237 GIMPIQSYSSFTRMTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPI 296
Query: 176 GEVPGVHMYTLNLEKSAVAILEQL------GLVDTSRVQ--RPLPWRHVPAGTARAVEQV 331
++ GVH YTLNLE+SA IL QL GLVD R + R LPWR +EQV
Sbjct: 297 AKIDGVHFYTLNLERSATRILMQLDGTVNSGLVDKIRTKSGRILPWRPSAMTGRSKMEQV 356
Query: 332 RPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSD 451
RP+ W+ RPK YV RT+DWD +P GRWG++ SPA+G LS+
Sbjct: 357 RPINWANRPKSYVLRTEDWDEFPNGRWGDSTSPAFGELSN 396
[56][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 158 bits (400), Expect = 2e-37
Identities = 73/172 (42%), Positives = 107/172 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI+PI Y + + K VP I D +E+IKDNDEA++ +GI +C++LLAS +
Sbjct: 238 GILPIQGYNSLRHLVQLSKLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDD 297
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
VPG+H+YTLN E++ V +L+++GL + + LPWR A R E VRP+FW+ RPK
Sbjct: 298 VPGIHVYTLNREEAVVKLLKRVGLWHEESIYKSLPWR-PSANGKRISEDVRPIFWASRPK 356
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
YV RT WD YP GRWG++ SPA+G L D+ + +++++ WG
Sbjct: 357 SYVHRTMMWDEYPNGRWGSSASPAFGELKDYHIF--YLKNTSKKDELLKMWG 406
[57][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 152 bits (385), Expect = 1e-35
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 9/181 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
GIMPI +Y GFK+MT FCKTKVP I+D LE +K +D+ VK G+E+ V MC Q+++ G
Sbjct: 185 GIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGV 244
Query: 179 ----EVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFW 346
G+H YTLNLE S I+E+L +VD R LPWR A ++R E VRP+FW
Sbjct: 245 DHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKA-SSRQEENVRPIFW 303
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARAD----W 514
R K +++RT WD +P GR GN S AYG D + R + E +EK AD W
Sbjct: 304 RNRQKSFIQRTSSWDEFPNGRLGNQASAAYG---DFELNFRSYSKET-QEKVAADRRRMW 359
Query: 515 G 517
G
Sbjct: 360 G 360
[58][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 151 bits (382), Expect = 2e-35
Identities = 71/156 (45%), Positives = 98/156 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R +C+ ++P + D LE +KD+D V+ G +L MC+++L SG+
Sbjct: 212 GIMPISTYASFMRRANWCQIQIPQDFLDQLEPVKDDDMRVRELGTQLVADMCQKMLDSGK 271
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ +H YT+NLEK+ V +LE+L L PLPWR A R E VRP+FW R +
Sbjct: 272 IKHLHFYTMNLEKATVMVLERLNLPAQDSAVAPLPWRPSLA-LGRQDETVRPIFWKNRKQ 330
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRR 469
YV RTQDWD +P GRWG++RSPA+G L + + R
Sbjct: 331 SYVARTQDWDEFPNGRWGDSRSPAFGELETYGVLLR 366
[59][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 151 bits (381), Expect = 3e-35
Identities = 75/151 (49%), Positives = 97/151 (64%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
GIMPI +Y GFK+MT FCKTKVP I+D LE +K +D+ VK G+E+ V MC Q+++ G
Sbjct: 185 GIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIMSYGV 244
Query: 179 ----EVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFW 346
G+H YTLNLE S I+E+L +VD R LPWR A ++R E VRP+FW
Sbjct: 245 DHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKA-SSRQEENVRPIFW 303
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R K +++RT WD +P GR GN S AYG
Sbjct: 304 RNRQKSFIQRTSSWDEFPNGRLGNQASAAYG 334
[60][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 149 bits (377), Expect = 9e-35
Identities = 75/175 (42%), Positives = 109/175 (62%), Gaps = 2/175 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
G+MPI TYGGF+R T T VP DAL+ ++D+D+ V+ G L MC++++ +G
Sbjct: 228 GVMPIQTYGGFQRATARFGTLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGL 287
Query: 179 EVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTA-RAVEQVRPVFWSKR 355
+ G+H+YT+NLEK + +L+ LGL + PLPW P+ T R E++RP+FW+ R
Sbjct: 288 GISGLHIYTMNLEKGSRMLLDYLGLTPSVNQVSPLPW--TPSLTPKRREEKIRPIFWANR 345
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWGA 520
K YV RT+ WD +P GRWG+ RSPAYG + + R+ N E+A+ WGA
Sbjct: 346 AKSYVNRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYSN-----EEAKEMWGA 395
[61][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 147 bits (371), Expect = 4e-34
Identities = 72/165 (43%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPIM Y KR+ + ++P I + LE IK +D+AV+ YG E + MCR+LL +G
Sbjct: 269 GIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGS 328
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
P +H+YT+N E S IL+ LGL R PW++ R +E VRP++WS RP+
Sbjct: 329 APSIHLYTMNREGSIREILKALGLWKLEG-DRVFPWKNRSQHPIRCLESVRPIYWSFRPR 387
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQF--MRRHRNGEAR 490
Y+ RT+DWD +P GRWGN+ SPA+G +S + + RNG+ R
Sbjct: 388 SYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDR 432
[62][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 147 bits (371), Expect = 4e-34
Identities = 72/165 (43%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPIM Y KR+ + ++P I + LE IK +D+AV+ YG E + MCR+LL +G
Sbjct: 319 GIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGS 378
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
P +H+YT+N E S IL+ LGL R PW++ R +E VRP++WS RP+
Sbjct: 379 APSIHLYTMNREGSIREILKALGLWKLEG-DRVFPWKNRSQHPIRCLESVRPIYWSFRPR 437
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQF--MRRHRNGEAR 490
Y+ RT+DWD +P GRWGN+ SPA+G +S + + RNG+ R
Sbjct: 438 SYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDR 482
[63][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 147 bits (371), Expect = 4e-34
Identities = 77/174 (44%), Positives = 103/174 (59%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI+PI + +VP I D L+ IKDND A++ YG++ + MCR+LL SG
Sbjct: 208 GILPIQ----------LSRLEVPKSIMDDLQTIKDNDVAIRNYGVQKAINMCRELLDSGL 257
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL--VDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
VPG+H YTLN E + IL LGL +D + RPLPWR A R E VRP+FW+ R
Sbjct: 258 VPGLHFYTLNREVATREILTALGLWCMDPA-ASRPLPWR-ASANQKRFTEDVRPIFWASR 315
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
PK Y+ RT DWD +P GRWGN+ +PA+ SDH + +A++E+ WG
Sbjct: 316 PKSYLYRTSDWDEFPNGRWGNSSAPAFRDFSDHHLF--YLRSKAKKEQMLKMWG 367
[64][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 147 bits (370), Expect = 6e-34
Identities = 69/151 (45%), Positives = 96/151 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPIM Y KR+ + ++P I D LE IK +D+AV+ YG E + MCR+LL +G
Sbjct: 247 GIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGT 306
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
P +H+YT+N E S IL+ LGL R PW++ R +E VRP++WS RP+
Sbjct: 307 APSIHLYTMNREGSIREILKSLGLWKLEG-DRVFPWKNRSQHPIRCLESVRPIYWSFRPR 365
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RT+DWD +P GRWGN+ SPA+G +S +
Sbjct: 366 SYITRTRDWDQFPNGRWGNSSSPAFGDVSSY 396
[65][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 147 bits (370), Expect = 6e-34
Identities = 69/151 (45%), Positives = 96/151 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPIM Y KR+ + ++P I D LE IK +D+AV+ YG E + MCR+LL +G
Sbjct: 268 GIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGT 327
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
P +H+YT+N E S IL+ LGL R PW++ R +E VRP++WS RP+
Sbjct: 328 APSIHLYTMNREGSIREILKSLGLWKLEG-DRVFPWKNRSQHPIRCLESVRPIYWSFRPR 386
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RT+DWD +P GRWGN+ SPA+G +S +
Sbjct: 387 SYITRTRDWDQFPNGRWGNSSSPAFGDVSSY 417
[66][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 146 bits (368), Expect = 9e-34
Identities = 70/152 (46%), Positives = 96/152 (63%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
GIMPI T+ GF + T TK+P DALE +K +DE V+ G +L MCR++L SG
Sbjct: 172 GIMPIQTWNGFIKATNLASTKIPQFFLDALEPVKSDDEKVREVGTKLVADMCRKILDSGL 231
Query: 179 EVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
+ G+H YT+NLEK +LE+L LV +PLPWR R E +RP+FW+ R
Sbjct: 232 GIRGLHFYTMNLEKGTRMLLEELNLVPRIETIKPLPWRQCLTPNRRN-ETIRPIFWANRT 290
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
K Y+ RT++WD YP GR+G++RSPAYG + +
Sbjct: 291 KSYISRTENWDEYPNGRFGDSRSPAYGEIDGY 322
[67][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 144 bits (363), Expect = 4e-33
Identities = 74/150 (49%), Positives = 97/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K KVP+E +ALE +K++D AV+ G L MCRQL+A+G
Sbjct: 211 GIMPIQTYASFIRRSNWTKVKVPSEWMEALEPVKNDDSAVRDIGKTLIANMCRQLIAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV--DTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +L++L L + S +QRPLPWR G R E VRPVFW R
Sbjct: 270 IKHLHFYTMNLAQATQLVLKELELTPSEDSPIQRPLPWRP-SLGLGRRSEDVRPVFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
YV RTQ WD YP GRW ++RSPA+G L
Sbjct: 329 NSSYVARTQTWDEYPNGRWTDSRSPAFGEL 358
[68][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 144 bits (362), Expect = 5e-33
Identities = 74/157 (47%), Positives = 96/157 (61%), Gaps = 7/157 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
GIMP+ +Y +MT FC VP+ + D L I+ +DEAVK G ++ MC Q+L++G
Sbjct: 202 GIMPVQSYSSLVKMTQFCGISVPSAVMDRLSNIRLDDEAVKQVGCKIVAEMCEQILSAGL 261
Query: 179 --EVPGVHMYTLNLEKSAVAILEQLGLVDTSR----VQRPLPWRHVPAGTARAVEQVRPV 340
+V G H YTLNLE+S IL LG S +R LPW+ A R+ E VRP+
Sbjct: 262 EVDVDGFHFYTLNLERSTTRILTSLGAGSISEQARSTRRVLPWKP-SAMENRSKEDVRPI 320
Query: 341 FWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSD 451
WS RPK YV RT DWD +P GRWG++ SPA+G LSD
Sbjct: 321 NWSNRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSD 357
[69][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 143 bits (360), Expect = 8e-33
Identities = 70/152 (46%), Positives = 93/152 (61%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
GI PI T+ GF+R T K VP DALE IK++DE V+ G L MCR++L
Sbjct: 212 GIAPIQTWNGFQRATSLAKIVVPQSFLDALEPIKNDDEKVREVGTRLVADMCRRILKEDI 271
Query: 179 EVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRP 358
+ G+H YT+NLEK +LE+L LV +PLPWR R E +RP+FW+ R
Sbjct: 272 GIRGLHFYTMNLEKGTKMLLEELNLVPRIETIKPLPWRQSLTPNRRQ-ESIRPIFWANRT 330
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
K Y+ RT++WD YP GR+G++RSPAYG L +
Sbjct: 331 KSYISRTENWDEYPNGRFGDSRSPAYGELDGY 362
[70][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 140 bits (354), Expect = 4e-32
Identities = 69/153 (45%), Positives = 101/153 (66%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + +ALE +K++D AV+ G L MC+++LASG
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ IL++LGL+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[71][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 140 bits (354), Expect = 4e-32
Identities = 69/153 (45%), Positives = 101/153 (66%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + +ALE +K++D AV+ G L MC+++LASG
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVADMCKKILASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ IL++LGL+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IYHLHFYTMNLQQATKMILDELGLIPSHKTPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[72][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 140 bits (353), Expect = 5e-32
Identities = 68/151 (45%), Positives = 95/151 (62%), Gaps = 2/151 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + D LE +K +D V+ G +L MCR+LLASG+
Sbjct: 211 GIMPISTYDAFMRRSNWTKIRIPPDWLDKLEPVKADDAKVREIGTKLVAEMCRKLLASGQ 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV--DTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ ILE+L L+ + + + +PLPWR G R E VRP+FW R
Sbjct: 271 IHHLHFYTMNLAQATRLILEELRLLPSEEAPLHKPLPWRR-SLGLRRRSEDVRPIFWRNR 329
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALS 448
Y+ RT DWD YP GRW + RSPA+G L+
Sbjct: 330 NASYIARTADWDEYPNGRWTDARSPAFGELN 360
[73][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 140 bits (352), Expect = 7e-32
Identities = 68/151 (45%), Positives = 95/151 (62%), Gaps = 2/151 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + + LE +K +D V+ G +L MCR+LLASG
Sbjct: 211 GIMPISTYDAFMRRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGH 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV--DTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ ILE+L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 271 IHHLHFYTMNLAQATRLILEELRLLPSEEAPLQKPLPWRR-SLGLRRRSEDVRPIFWRNR 329
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALS 448
Y+ RT DWD YP GRW + RSPA+G L+
Sbjct: 330 NASYIARTADWDEYPNGRWTDARSPAFGELN 360
[74][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 139 bits (351), Expect = 9e-32
Identities = 72/173 (41%), Positives = 106/173 (61%), Gaps = 1/173 (0%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI+PI +Y +R+ + +P I +LE IK++D+AV+ +GI V +CR LL++G
Sbjct: 266 GILPIQSYESIRRVAELSQLVIPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGS 325
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWR-HVPAGTARAVEQVRPVFWSKRP 358
+H++TLN E S+ IL+QLGL S + R LPWR + R E VRP+FWS RP
Sbjct: 326 ATSIHLFTLNREASSREILQQLGLWPRSPM-RALPWRLFGESHPVRCKEDVRPIFWSMRP 384
Query: 359 KDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K YV RT++WD +P GRWGN+ SPA+ L D+ + G+ R++ +G
Sbjct: 385 KSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLF--YLKGQPTRDEQLRMYG 435
[75][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 139 bits (350), Expect = 1e-31
Identities = 77/174 (44%), Positives = 102/174 (58%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R K K+P DALE +K++D AV+ G L MCR+LLA+G
Sbjct: 211 GIMPIATYASFLRRANHMKAKIPQAWLDALEPVKNDDVAVRDIGKSLVAEMCRKLLANG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L ++ +Q LPW+ G R E VRP+FW R
Sbjct: 270 IHHLHFYTMNLAQATRMVLEELNWAPSAERPLQHALPWKQ-SKGLGRREEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K YV RTQDWD +P GRWG++RSPA+G L + N EA R+K WG
Sbjct: 329 NKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTN-EANRKK----WG 377
[76][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 139 bits (349), Expect = 2e-31
Identities = 68/153 (44%), Positives = 99/153 (64%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P +ALE +K++D AV+ G L MC+++LASG
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L++LGL+ + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[77][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 139 bits (349), Expect = 2e-31
Identities = 68/153 (44%), Positives = 99/153 (64%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P +ALE +K++D AV+ G L MC+++LASG
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L++LGL+ + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[78][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 139 bits (349), Expect = 2e-31
Identities = 68/153 (44%), Positives = 99/153 (64%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P +ALE +K++D AV+ G L MC+++LASG
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIQIPPGWLEALEPVKNDDAAVRNLGKSLVANMCKKMLASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L++LGL+ + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IHHLHFYTMNLQQATKMVLDELGLIPSHETPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[79][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 138 bits (348), Expect = 2e-31
Identities = 71/150 (47%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K +VP +ALE K++D AVK G +L MCR++L SG
Sbjct: 211 GIMPISTYAAFLRRSNWVKCRVPPSWMEALEPCKNDDAAVKQIGKKLVSEMCRKILDSG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S +LE+L L+ +S +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IRHLHFYTMNLAQSTKMVLEELDLIPSSETPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
+ YV RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 HQSYVARTQTWDEFPNGRWTDSRSPAFGEL 358
[80][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 138 bits (347), Expect = 3e-31
Identities = 70/153 (45%), Positives = 95/153 (62%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K ++P E +ALE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPIQTYAAFMRRANWTKIRIPPEWLEALEPVKNDDAAVKEIGKGLIADMCRRLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S +LE+L L + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQSTQLVLEELNLTPSEETPLQKPLPWRP-SLGLNRRGEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RTQ WD +P GRW ++RSPA+G L +
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGELDSY 361
[81][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 138 bits (347), Expect = 3e-31
Identities = 71/150 (47%), Positives = 95/150 (63%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R T + K K+P +ALE +K++D AVK G L MCR+LL +G
Sbjct: 211 GIMPISTYAAFIRRTNWVKCKIPKGWMEALEPVKNDDAAVKQIGRALVSEMCRKLLDNG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S +LE+L L ++ +Q+PLPWR G R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQSTTMVLEELNLKPSTETPLQKPLPWRK-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
+ YV RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 HQSYVARTQSWDEFPNGRWTDSRSPAFGEL 358
[82][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 138 bits (347), Expect = 3e-31
Identities = 70/150 (46%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K ++P + +ALE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ A+LE+L L+ + +QRPLPWR A R E VRP+FW R
Sbjct: 270 IKHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRG-EDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
Y+ RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGEL 358
[83][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 137 bits (346), Expect = 3e-31
Identities = 77/174 (44%), Positives = 103/174 (59%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K+P E DALE +K++D AV+ G L MCR+LLA+G
Sbjct: 211 GIMPIATYASFLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L ++ +Q LPW+ G R E VRP+FW R
Sbjct: 270 IHHLHFYTMNLAQATRMLLEELQWAPSADRPLQHALPWKQ-SKGLGRREEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K YV RTQDWD +P GRWG++RSPA+G L + N EA R+K WG
Sbjct: 329 NKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGSN-EANRKK----WG 377
[84][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 137 bits (346), Expect = 3e-31
Identities = 70/150 (46%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K ++P + +ALE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ A+LE+L L+ + +QRPLPWR A R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRG-EDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
Y+ RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGEL 358
[85][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 137 bits (346), Expect = 3e-31
Identities = 70/150 (46%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K ++P + +ALE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPISTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLVADMCRRLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ A+LE+L L+ + +QRPLPWR A R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQATQAVLEELKLIPSEETPLQRPLPWRPSLALNRRG-EDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
Y+ RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGEL 358
[86][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 137 bits (344), Expect = 6e-31
Identities = 76/167 (45%), Positives = 102/167 (61%), Gaps = 11/167 (6%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI +Y F R T +C+ VP + LE +KD+D+ V+ G EL V +C++LL SG
Sbjct: 216 GIMPITSYPSFIRRTQWCQINVPDNFLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGY 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-------PLPWRHVPAGTARAVEQVRPV 340
V +HMYT+NLEK+++ ILE+L L+ S V + PLPWR R E VRP+
Sbjct: 276 VNHLHMYTMNLEKASLMILEKLDLLKRSNVGKDVIEPLEPLPWRK-SLNPKRRNELVRPI 334
Query: 341 FWSKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGALS--DHQFMRR 469
FW KRP YV RT W D +P GR+G++ SPAYG L H +R+
Sbjct: 335 FWQKRPYSYVARTSLWNEDEFPNGRFGDSSSPAYGDLDLCGHSLIRQ 381
[87][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 137 bits (344), Expect = 6e-31
Identities = 67/150 (44%), Positives = 91/150 (60%), Gaps = 4/150 (2%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DAL IK++D A++ G +L MC++L+ SG
Sbjct: 214 GIMPISTYSAFIRRANWSQVAIPQHFLDALNPIKEDDYAIREVGTQLVSEMCQKLIDSGY 273
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV----DTSRVQRPLPWRHVPAGTARAVEQVRPVFWS 349
V +H YT+NLE+S V ILE+L LV D V LPWR +R+ E +RP+FW
Sbjct: 274 VNHLHFYTMNLERSTVMILEKLNLVESIKDNDAVVEILPWRK-SLNPSRSKESIRPIFWQ 332
Query: 350 KRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 333 NRKYSYISRTSGWDEFPNGRWGDSRSPAFG 362
[88][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 137 bits (344), Expect = 6e-31
Identities = 72/152 (47%), Positives = 95/152 (62%), Gaps = 4/152 (2%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R K+P + S +LEA+K++D AV+ G +L MCR+++ +G
Sbjct: 211 GIMPINTYASFLRRCNHMGCKIPPKWSASLEAVKNDDSAVRNIGKDLVAEMCRRIIQAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPL----PWRHVPAGTARAVEQVRPVFWS 349
V +H YT+NL ++ +LE+L L T QRPL PWR G R E VRP+FW
Sbjct: 270 VHHLHFYTMNLAQATRMVLEELNL--TPSTQRPLKHALPWRQ-SLGLGRREEDVRPIFWK 326
Query: 350 KRPKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
R K YV RTQDWD +P GRWG++RSPA+G L
Sbjct: 327 NRNKSYVARTQDWDEFPNGRWGDSRSPAFGEL 358
[89][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 136 bits (343), Expect = 8e-31
Identities = 69/150 (46%), Positives = 97/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K KVP +ALE +K++D AVK G +L MC+++L SG
Sbjct: 211 GIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT--SRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKPLPWRQ-SLGLGRRDEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
+ YV RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 HQSYVARTQTWDEFPNGRWTDSRSPAFGEL 358
[90][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 136 bits (343), Expect = 8e-31
Identities = 67/153 (43%), Positives = 99/153 (64%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + +ALE +K++D AV+ G L MCR++LA+G
Sbjct: 102 GIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAG- 160
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L +L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 161 IYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 219
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 220 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 252
[91][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 136 bits (343), Expect = 8e-31
Identities = 69/150 (46%), Positives = 97/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K KVP +ALE +K++D AVK G +L MC+++L SG
Sbjct: 211 GIMPISTYASFLRRSNWVKCKVPESWMEALEPVKNDDAAVKQIGKKLVANMCQKILDSG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT--SRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IRHLHFYTMNLAQATKMVLEELKLIPSYETPLQKPLPWRQ-SLGLGRRDEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
+ YV RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 HQSYVARTQTWDEFPNGRWTDSRSPAFGEL 358
[92][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 136 bits (343), Expect = 8e-31
Identities = 67/153 (43%), Positives = 99/153 (64%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K ++P + +ALE +K++D AV+ G L MCR++LA+G
Sbjct: 211 GIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L +L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 270 IYHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 329 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 361
[93][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 136 bits (343), Expect = 8e-31
Identities = 70/151 (46%), Positives = 91/151 (60%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K+P +ALE IKD+D V+ G EL MC+QL+ SG
Sbjct: 212 GIMPISTYAAFIRRAKWSEIKIPPHFLEALEPIKDDDFLVREKGTELVSEMCQQLIESGY 271
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ-----RPLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLEK+ V ILE+L LV+ + LPWR R+ E +RP+FW
Sbjct: 272 VNHLHFYTMNLEKATVMILEKLNLVEAIKSHDLVGGTELPWRK-SLHPERSKESIRPIFW 330
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R YV RT WD +P GRWG++RSPA+G
Sbjct: 331 QNRKYSYVSRTATWDEFPNGRWGDSRSPAFG 361
[94][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 136 bits (343), Expect = 8e-31
Identities = 69/150 (46%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K ++P E +ALE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPISTYAAFIRRANWTKARIPPEWLEALEPVKNDDAAVKEIGKRLIAEMCRKLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ ++L++L L+ + +QRPLPWR G R E VRP+FW R
Sbjct: 270 LNHLHFYTMNLAQATQSVLDELKLIPSEETPLQRPLPWRP-SLGLNRRGEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
Y+ RTQ WD +P GRW ++RSPA+G L
Sbjct: 329 NSSYIARTQIWDEFPNGRWTDSRSPAFGEL 358
[95][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 136 bits (342), Expect = 1e-30
Identities = 70/150 (46%), Positives = 93/150 (62%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + KT +P + +ALE +K++D AVK G L MCR+L+ASG
Sbjct: 211 GIMPIQTYAAFIRRANWTKTHIPPDWLEALEPVKNDDAAVKQVGKRLIADMCRRLIASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S +LE+L L T+ + RPLPWR G R E VRP+FW R
Sbjct: 270 IKHLHFYTMNLAQSTQLVLEELELTPTAEAPIPRPLPWRP-SLGLNRREEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
Y+ RT WD +P GRW ++RSPA+G L
Sbjct: 329 NSSYIARTAIWDEFPNGRWTDSRSPAFGEL 358
[96][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 135 bits (340), Expect = 2e-30
Identities = 71/155 (45%), Positives = 98/155 (63%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + +C+ VP L+ +KD+D+AV+ G EL +MC++LL SG
Sbjct: 214 GIMPITTYAAFLRRSSWCQINVPEAFMAKLDPVKDDDQAVREVGTELVAQMCQKLLDSGY 273
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV----DTSRVQ-RPLPWRHVPAGTARAVEQVRPVFW 346
V +HMYT+NLEK+ + +L++LGL+ D R + P+PWR R E VRP+FW
Sbjct: 274 VTHLHMYTMNLEKACIMVLDRLGLLSEDEDIFRDEVVPMPWRK-SLHPQRRNESVRPIFW 332
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
KRP YV RT W D +P GR+G++ SPA+G L
Sbjct: 333 QKRPYSYVARTSQWTADEFPNGRFGDSSSPAFGDL 367
[97][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 135 bits (340), Expect = 2e-30
Identities = 67/158 (42%), Positives = 91/158 (57%), Gaps = 12/158 (7%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R +C+ VP+ L+A KD+D V+ G +L MC +L+ SG
Sbjct: 197 GIMPISTYASFSRRAKWCQINVPSWFQKQLDASKDDDSEVRCLGTQLVADMCLKLVESGY 256
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTS------------RVQRPLPWRHVPAGTARAVE 325
V +H YT+NLEKS + +LE+L L+DT Q +PWR R E
Sbjct: 257 VNHLHFYTMNLEKSTIMVLEKLQLIDTHNQPVASVRDCGVESQVTVPWRR-SLNPTRVNE 315
Query: 326 QVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
+RP+FWS R Y+ RT +WD +P GRWG++RSPA+G
Sbjct: 316 SIRPIFWSNRKFTYISRTSNWDEFPNGRWGDSRSPAFG 353
[98][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 135 bits (340), Expect = 2e-30
Identities = 67/153 (43%), Positives = 97/153 (63%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + KT++P + +ALE +K++D AV+ G L MCR+L+A+G
Sbjct: 211 GIMPIQTYAAFIRRSDWTKTRIPPDWLEALEPVKNDDAAVRDIGKRLIADMCRRLIAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S +L++L L+ + +QR LPWR G R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQSTQLVLDELNLMPSEETPLQRALPWRP-SLGLNRRAEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RTQ WD +P GRW ++RSPA+G L +
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGELDSY 361
[99][TOP]
>UniRef100_A6SLU6 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SLU6_BOTFB
Length = 390
Score = 135 bits (339), Expect = 2e-30
Identities = 68/150 (45%), Positives = 95/150 (63%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R K+P + S ALE +K++D AV+ G +L MCR+++ +G
Sbjct: 211 GIMPINTYASFLRRCNHMGCKIPPKWSAALEEVKNDDAAVRNIGKDLVAEMCRRIIEAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
V +H YT+NL ++ +LE+L L +++ ++ LPWR G R E VRP+FW R
Sbjct: 270 VHHLHFYTMNLAQATRMVLEELSLTPSNQRPLKHALPWRQ-SLGLGRREEDVRPIFWKNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
K YV RTQDWD +P GRWG++RSPA+G L
Sbjct: 329 NKSYVARTQDWDEFPNGRWGDSRSPAFGEL 358
[100][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 134 bits (338), Expect = 3e-30
Identities = 67/151 (44%), Positives = 90/151 (59%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DAL+ IKD+D V+ G EL MC++LL SG
Sbjct: 211 GIMPISTYSAFLRRAKWSEIAIPQHFLDALDPIKDDDYLVREKGTELVSEMCQKLLESGY 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTARAVEQVRPVFW 346
+ +H YT+NLEK+ V ILE+L L++ + LPWR R+ E +RP+FW
Sbjct: 271 INHLHFYTMNLEKATVMILEKLNLIEAVKSNEIVGVTELPWRK-SLNPERSKESIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R YV RT WD +P GRWG++RSPA+G
Sbjct: 330 QNRKYSYVTRTATWDEFPNGRWGDSRSPAFG 360
[101][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 134 bits (336), Expect = 5e-30
Identities = 67/153 (43%), Positives = 94/153 (61%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + K +P + + LE +K++D AVK G L MCR+LLA+G
Sbjct: 211 GIMPIQTYAAFIRRANWTKIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMCRRLLAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +L++L L+ + +QRPLPWR G R E VRP+FW R
Sbjct: 270 INHLHFYTMNLAQATQLVLDELKLLPSEETPIQRPLPWRP-SLGLNRRAEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
Y+ RTQ WD +P GRW ++RSPA+G L +
Sbjct: 329 NSSYIARTQTWDEFPNGRWTDSRSPAFGELDSY 361
[102][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 134 bits (336), Expect = 5e-30
Identities = 68/150 (45%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + ++P E LE IK +D AV+ G +L V +CR++LA+G
Sbjct: 206 GIMPIATYASFLRRANHMQARIPEEWLQRLEPIKTDDAAVRIVGRQLVVELCRKILAAG- 264
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL +S ILE L + + ++ LPW+ G R E VRP+FW R
Sbjct: 265 IHHLHFYTMNLAQSTALILEDLDWLPSPNKPLKHALPWKQ-SLGLGRREEDVRPIFWRNR 323
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
K YV RTQDWD +P GRWG++RSPA+G L
Sbjct: 324 NKSYVMRTQDWDEFPNGRWGDSRSPAFGEL 353
[103][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 133 bits (335), Expect = 6e-30
Identities = 70/158 (44%), Positives = 98/158 (62%), Gaps = 10/158 (6%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI +Y R +C+ ++P E + LE +KD+D+AV+ G L MCR++LASG
Sbjct: 214 GIMPITSYAALLRRAKWCQVRLPPEFLERLEPVKDDDQAVREIGTVLVADMCRKILASGH 273
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRV---QRP-----LPWRHVPAGTARAVEQVRP 337
V +H+YT+NLE++++ ILE+L L+DT +RP L WR R E VRP
Sbjct: 274 VTHLHLYTMNLERASLMILERLQLIDTGGAGVRRRPSTNETLTWRK-SLNPTRRKEGVRP 332
Query: 338 VFWSKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+FW +RP YV RT W D +P GR+G++ SPAYG L
Sbjct: 333 IFWQRRPYSYVARTSQWSADEFPNGRFGDSSSPAYGDL 370
[104][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 133 bits (335), Expect = 6e-30
Identities = 72/174 (41%), Positives = 100/174 (57%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R K+P E LE +K++D AV+ G L +CR++LA+G
Sbjct: 211 GIMPIATYASFLRRANHMNCKIPDEWMQRLEPVKNDDVAVRDIGKTLVAELCRKILAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L + + V++ LPW+ G R VE VRP+FW R
Sbjct: 270 IHHLHFYTMNLAQATRMVLEELDWMPSPDRPVKQALPWKR-SLGLGRQVEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K YV RTQDWD +P GRWG++RSPA+G L + N E+ R WG
Sbjct: 329 NKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTN-----EQNRQKWG 377
[105][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 132 bits (333), Expect = 1e-29
Identities = 65/151 (43%), Positives = 90/151 (59%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DALE IK++D V+A G EL MC +L+ SG
Sbjct: 211 GIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGY 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLE++ + ILE L L+++ + LPWR R+ E +RP+FW
Sbjct: 271 VNHLHFYTMNLERATIMILENLNLIESVKSHEVIGGSDLPWRK-SLHPQRSKESIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 330 QNRKYSYISRTSTWDEFPNGRWGDSRSPAFG 360
[106][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 132 bits (333), Expect = 1e-29
Identities = 65/151 (43%), Positives = 90/151 (59%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DALE IK++D V+A G EL MC +L+ SG
Sbjct: 211 GIMPISTYAAFIRRAKWSEVVIPQHFLDALEPIKEDDYLVRAKGTELVSEMCTKLIKSGY 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLE++ + ILE L L+++ + LPWR R+ E +RP+FW
Sbjct: 271 VNHLHFYTMNLERATIMILENLNLIESVKSHEVIGGSDLPWRK-SLHPQRSKESIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 330 QNRKYSYISRTSTWDEFPNGRWGDSRSPAFG 360
[107][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 132 bits (333), Expect = 1e-29
Identities = 66/153 (43%), Positives = 97/153 (63%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI T+ F R + + +P +DALE +K++D V+ G L MCR+L+A+G
Sbjct: 211 GIMPIHTHAAFLRRAQWTRCNIPQHWTDALEPVKNDDVEVREVGKMLVADMCRKLIAAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT--SRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L L+ + +++PLPWR G R E VRP+FW R
Sbjct: 270 ITHLHFYTMNLAQATRMVLEELDLLPDVEAPLEKPLPWRP-SLGLNRRDENVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQDWD +P GRWG++RSPA+G L +
Sbjct: 329 NRSYVARTQDWDEFPNGRWGDSRSPAFGELDSY 361
[108][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 132 bits (332), Expect = 1e-29
Identities = 67/151 (44%), Positives = 89/151 (58%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DAL+ IKD+D V+ G EL MC +LL SG
Sbjct: 211 GIMPISTYAAFIRRAKWSEIAIPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGY 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ-----RPLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLEK+ V ILE+L L++ + LPWR R+ E +RP+FW
Sbjct: 271 VNHLHFYTMNLEKATVMILEKLNLIEAIKSHDVVGGSELPWRK-SLHPERSKESIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 330 QHRKYSYISRTATWDEFPNGRWGDSRSPAFG 360
[109][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 132 bits (332), Expect = 1e-29
Identities = 67/153 (43%), Positives = 96/153 (62%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI T+ F R + + +P +DALE IK++D V+ G L MCR+L+ +G
Sbjct: 211 GIMPIHTHASFLRRAQWTRCNIPQHWTDALEPIKNDDVEVREVGKGLVADMCRRLIEAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT--SRVQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L L+ S +++PLPWR G R E VRP+FW R
Sbjct: 270 ITHLHFYTMNLAQATRMVLEELDLLPDPGSPLEKPLPWRP-SLGLNRRDENVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQDWD +P GRWG++RSPA+G L +
Sbjct: 329 NRSYVARTQDWDEFPNGRWGDSRSPAFGELDSY 361
[110][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 132 bits (331), Expect = 2e-29
Identities = 67/151 (44%), Positives = 89/151 (58%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P DAL+ IKD+D V+ G EL MC +LL SG
Sbjct: 211 GIMPISTYAAFIRRAKWSEIVIPQHFLDALDPIKDDDFLVRERGTELVSEMCNKLLQSGY 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ-----RPLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLEK+ V ILE+L L++ + LPWR R+ E +RP+FW
Sbjct: 271 VNHLHFYTMNLEKATVMILEKLNLIEAIKSHDVVGGSELPWRK-SLHPERSKESIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 330 QHRKYSYISRTATWDEFPNGRWGDSRSPAFG 360
[111][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 129 bits (325), Expect = 9e-29
Identities = 69/155 (44%), Positives = 96/155 (61%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + K+P D LE +KD+D+ V+ G EL V MC+++L SG
Sbjct: 216 GIMPITTYAAFLRRAQWGQIKIPQAFLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGY 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT-----SRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ + ILE+LGL+ + + LPWR R E+VRP+FW
Sbjct: 276 VKHLHIYTMNLEKAPLIILEKLGLLPSESEVNANPLASLPWRK-SLNPKRKNEEVRPIFW 334
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 335 KRRPYSYVARTSQWAMDEFPNGRFGDSSSPAFGDL 369
[112][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 129 bits (323), Expect = 2e-28
Identities = 71/174 (40%), Positives = 100/174 (57%), Gaps = 2/174 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R KVP E LE++K++D AV+ G L MCR++L++G
Sbjct: 211 GIMPIATYASFLRRANHMNCKVPEEWMAKLESVKNDDVAVRDIGKTLVADMCRKILSAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L + + +++ LPW+ G R E VRP+FW R
Sbjct: 270 IRHLHFYTMNLAQATRMVLEELDWLPSPDRPLKQALPWKQ-SLGFGRRDEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARADWG 517
K YV RTQDWD +P GRWG++RSPA+G L + N E+ R WG
Sbjct: 329 NKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGVGLTGSN-----EQNRKKWG 377
[113][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 128 bits (322), Expect = 2e-28
Identities = 64/150 (42%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R K+P E LE +K++D AV+ G L MCR+++ +G
Sbjct: 211 GIMPIATYASFIRRANHMNCKIPEEWMAKLEPVKNDDVAVREIGKTLVAEMCRKIVDAG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL ++ +LE+L + + ++R LPW+ G+ R E VRP+FW R
Sbjct: 270 IRHLHFYTMNLAQATRMVLEELDWLPSPNRPLKRALPWKQ-SLGSGRRDEDVRPIFWRNR 328
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGAL 445
K Y+ RTQDWD +P GRWG++RSPA+G L
Sbjct: 329 NKSYITRTQDWDEFPNGRWGDSRSPAFGEL 358
[114][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 128 bits (322), Expect = 2e-28
Identities = 70/161 (43%), Positives = 93/161 (57%), Gaps = 13/161 (8%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R +C +VP L + D+DE V+ G +L V MCR+LL SG
Sbjct: 204 GIMPISTYAAFLRRCSWCGVRVPDNFLQRLAPVSDDDELVREIGTQLVVDMCRRLLESGV 263
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL---------VDTSRVQRP--LPWRHVPAGTARAVEQ 328
V +H+YT+NLE+ + ILE+LGL +DT + P +PWR R E+
Sbjct: 264 VSHLHLYTMNLERPPLVILERLGLLPEASAEQSIDTFTNEPPAVVPWRR-SLNPQRRNEE 322
Query: 329 VRPVFWSKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
VRP+FW RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 323 VRPIFWKSRPYSYVARTSQWAADEFPNGRFGDSSSPAFGDL 363
[115][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 128 bits (321), Expect = 3e-28
Identities = 63/151 (41%), Positives = 88/151 (58%), Gaps = 5/151 (3%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P + LE IKD+D V+ G EL +MC +LL SG
Sbjct: 211 GIMPISTYAAFVRRAKWSQIAIPPHFLEVLEPIKDDDYLVREKGTELVSQMCTKLLQSGF 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTARAVEQVRPVFW 346
V +H YT+NLE++ + ILE L +++ + LPWR R+ E +RP+FW
Sbjct: 271 VNHLHFYTMNLERATIMILETLNIIEPVKAHENTGGDELPWRK-SLHPQRSKETIRPIFW 329
Query: 347 SKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 330 QNRKYSYITRTATWDEFPNGRWGDSRSPAFG 360
[116][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 126 bits (317), Expect = 8e-28
Identities = 69/177 (38%), Positives = 110/177 (62%), Gaps = 5/177 (2%)
Frame = +2
Query: 2 GIMPIM---TYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLA 172
GI+PI T ++M KVP EI + L++ K++ EA++A+GI+ +MC++L A
Sbjct: 230 GILPIQNLQTVRNLRKMN--FAVKVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFA 287
Query: 173 SGEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSK 352
SG+V G+H+YTLN+EK ++ILE L + + + LPW+ R+ E VRP+FW+
Sbjct: 288 SGKVQGIHLYTLNIEKPVMSILENLKISKEPELNK-LPWQ---LSDVRSGEDVRPIFWAS 343
Query: 353 RPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSD-HQFMRRHRNGEARRE-KARADWG 517
RP+ Y+ RT +W+ P GRWGN+ S ++G L D H F+ G +R++ + + WG
Sbjct: 344 RPRSYLIRTSNWEDMPNGRWGNSSSASFGDLKDYHLFL----TGTSRKDSELLSMWG 396
[117][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 126 bits (317), Expect = 8e-28
Identities = 68/155 (43%), Positives = 93/155 (60%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P S L+ IKD+DE V+ G L V MC++LL SG
Sbjct: 216 GIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGY 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT-----SRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ + ILE+L ++ T + LPWR R E+VRP+FW
Sbjct: 276 VSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPLAVLPWRK-SLNPKRKNEEVRPIFW 334
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 335 KRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDL 369
[118][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 126 bits (317), Expect = 8e-28
Identities = 68/155 (43%), Positives = 93/155 (60%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P S L+ IKD+DE V+ G L V MC++LL SG
Sbjct: 216 GIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGY 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT-----SRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ + ILE+L ++ T + LPWR R E+VRP+FW
Sbjct: 276 VSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPLAVLPWRK-SLNPKRKNEEVRPIFW 334
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 335 KRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDL 369
[119][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 126 bits (317), Expect = 8e-28
Identities = 67/154 (43%), Positives = 91/154 (59%), Gaps = 8/154 (5%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + F R + K+P D L +KD+DE V+ G+EL V MCR+L+ASG
Sbjct: 211 GIMPIQAWDSFIRRAKWSGVKIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL--------VDTSRVQRPLPWRHVPAGTARAVEQVRP 337
+ +H YT+NLEK+ I+E+LGL VDT+ V+ + + R E VRP
Sbjct: 270 ITRLHFYTMNLEKAVKMIIERLGLLDENLAPIVDTNNVELT----NASSQDRRINEGVRP 325
Query: 338 VFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
+FW R + YV RT WD P GRWG++RSPA+G
Sbjct: 326 IFWRTRNESYVSRTDQWDELPHGRWGDSRSPAFG 359
[120][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 125 bits (314), Expect = 2e-27
Identities = 64/154 (41%), Positives = 93/154 (60%), Gaps = 3/154 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + F++ VP+ +AL ++ +DE V+ G +L MC+ +L + E
Sbjct: 215 GIMPIQNWEKFEKWVQRENIIVPSHFYEALNPVRGDDEKVRQVGTKLVADMCKTILDNKE 274
Query: 182 --VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGT-ARAVEQVRPVFWSK 352
+ G+H+YTLNLEK A +L +LG PLPWR P+ T +R E +RP+FW+
Sbjct: 275 AGIKGLHIYTLNLEKGARMLLRELGFEGRREQIAPLPWR--PSLTPSRREETIRPIFWAN 332
Query: 353 RPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
R + Y+ RT DWD +P GRWG++RSPAYG L +
Sbjct: 333 RTRSYLSRTADWDEFPNGRWGDSRSPAYGDLDGY 366
[121][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 125 bits (314), Expect = 2e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R +C +P E D L+ IKD+D+ V+ G +L V +C++LL SG
Sbjct: 215 GIMPITTYAAFLRRANWCDVHIPQEYFDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGY 274
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT-----SRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ IL+++ L+ + LPWR R E+VRP+FW
Sbjct: 275 VSHLHIYTMNLEKAPQMILDRMELLPSHDEPLDNHLAILPWRK-SLNPQRRNEEVRPIFW 333
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 334 QRRPYSYVARTSQWSVDEFPNGRFGDSSSPAFGDL 368
[122][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 124 bits (312), Expect = 3e-27
Identities = 67/155 (43%), Positives = 92/155 (59%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P S L+ IKD+DE V+ G L V MC++LL SG
Sbjct: 27 GIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGY 86
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD-----TSRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ + ILE+L ++ + LPWR R E+VRP+FW
Sbjct: 87 VSHLHIYTMNLEKAPLMILERLNILPMESEFNAHPLAVLPWRK-SLNPKRKNEEVRPIFW 145
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 146 KRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDL 180
[123][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 124 bits (312), Expect = 3e-27
Identities = 67/155 (43%), Positives = 92/155 (59%), Gaps = 7/155 (4%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R + + +P S L+ IKD+DE V+ G L V MC++LL SG
Sbjct: 216 GIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGY 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD-----TSRVQRPLPWRHVPAGTARAVEQVRPVFW 346
V +H+YT+NLEK+ + ILE+L ++ + LPWR R E+VRP+FW
Sbjct: 276 VSHLHIYTMNLEKAPLMILERLNILPMESEFNAHPLAVLPWRK-SLNPKRKNEEVRPIFW 334
Query: 347 SKRPKDYVKRTQDW--DSYPAGRWGNTRSPAYGAL 445
+RP YV RT W D +P GR+G++ SPA+G L
Sbjct: 335 KRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDL 369
[124][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 122 bits (307), Expect = 1e-26
Identities = 65/183 (35%), Positives = 104/183 (56%), Gaps = 10/183 (5%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI ++ F R + ++P DALE +KD+D V+ G EL MC++L+ +G
Sbjct: 212 GIMPIQSWSTFNRRCEWSGVRIPQHFIDALEPLKDDDALVREKGSELMAEMCQKLVDNG- 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD----------TSRVQRPLPWRHVPAGTARAVEQV 331
+ +H YT+NLEK+ I+E++GL++ TS ++ P + + R E V
Sbjct: 271 ITRLHFYTMNLEKATKMIIEKMGLLNQYIETPKNELTSHIRSPSQLQFLD--NPRPNETV 328
Query: 332 RPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDHQFMRRHRNGEARREKARAD 511
RP+FW R + ++ RT+ WD +P GRWG++RSPA+G +F +H + + RA
Sbjct: 329 RPMFWKTRSQSFISRTEQWDEFPNGRWGDSRSPAFG-----EFDPKHHGLKQTDAEIRAL 383
Query: 512 WGA 520
WG+
Sbjct: 384 WGS 386
[125][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 119 bits (297), Expect = 2e-25
Identities = 63/153 (41%), Positives = 92/153 (60%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI T +P + +ALE +K++D AV+ G L MCR++LA+G
Sbjct: 211 GIMPIHT--------------IPPDWLEALEPVKNDDVAVRNLGKSLVANMCRKMLAAG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKR 355
+ +H YT+NL+++ +L +L L+ + + +Q+PLPWR G R E VRP+FW R
Sbjct: 256 IHHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQ-SLGLGRREEDVRPIFWRHR 314
Query: 356 PKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ YV RTQ WD YP GRW ++RSPA+G L +
Sbjct: 315 HQSYVARTQTWDEYPNGRWTDSRSPAFGELDTY 347
[126][TOP]
>UniRef100_C6T731 Methylenetetrahydrofolate reductase n=1 Tax=Glycine max
RepID=C6T731_SOYBN
Length = 344
Score = 118 bits (296), Expect = 2e-25
Identities = 58/93 (62%), Positives = 73/93 (78%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y GF RMTGFCKTK+PA+I ALE IKDN+EAVKAYGI LG MC+++LA G
Sbjct: 221 GIMPINNYKGFIRMTGFCKTKIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHG- 279
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRP 280
+ +H+YTLN+EKSA+AIL LGL++ ++ P
Sbjct: 280 INTLHLYTLNMEKSALAILMNLGLIEETKFLGP 312
[127][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 115 bits (289), Expect = 1e-24
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 83 DALEAIKDNDEAVKAYGIELGVRMCRQLLASGE--VPGVHMYTLNLEKSAVAILEQLGLV 256
DAL+ +K++DE V+ G L MC+++L + + GVH+YT+NLE+ + +LE LGL
Sbjct: 163 DALDPVKEDDEQVRIVGTRLVGDMCKKILEHPDLDIHGVHIYTMNLERGSRMLLEYLGLT 222
Query: 257 DTSRVQRPLPWRHVPAGTA-RAVEQVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPA 433
+ + PLPWR P+ T R E +RP+FW+ R K Y+ RT WD +P GRWG+ RSPA
Sbjct: 223 PSVQQLHPLPWR--PSLTPKRREENIRPIFWANRAKSYIDRTDAWDEFPNGRWGDARSPA 280
Query: 434 YG 439
YG
Sbjct: 281 YG 282
[128][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 103 bits (258), Expect = 5e-21
Identities = 64/176 (36%), Positives = 85/176 (48%), Gaps = 25/176 (14%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y F+RMT CK +VP I DALE IK +D AVK YG+ L + M ++ +
Sbjct: 274 GIMPIQNYSSFRRMTNLCKVQVPQLILDALEPIKSDDAAVKEYGVSLSIHMVGRIFLETD 333
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKR-- 355
V G H+ +LNLEKS ILE LG Q+ R +E + S R
Sbjct: 334 VRGFHLCSLNLEKSIERILEGLGWKTDVGAQQESDARLRGIPAHLHLENTKNQMLSDRTG 393
Query: 356 ---PKDY--------------------VKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
PKD+ V T WD +P GR+G++RSPA+G + +
Sbjct: 394 TNTPKDFKVTTQEALARTLARTSSSYQVPETSTWDEFPNGRYGDSRSPAFGEMDGY 449
[129][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 95.9 bits (237), Expect = 1e-18
Identities = 58/156 (37%), Positives = 79/156 (50%), Gaps = 10/156 (6%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R+T C T+VPA I++ L I +D+ VK YG++L V+M R+L G
Sbjct: 213 GIMPIQTYASFVRLTKLCGTRVPACITEDLAPISHDDQLVKDYGVKLAVQMIRRLRLEGG 272
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV-DTSRVQRPLPWRHVP---------AGTARAVEQV 331
+ G H TLNLEKS +LE L DT P P TA +
Sbjct: 273 IQGFHFCTLNLEKSVQRVLETLRWAGDTPGTMEPPAEMGPPDLLITPTSATDTATSTLAT 332
Query: 332 RPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
V + + + WD +P GR+G+ +SPA+G
Sbjct: 333 ISVTDGEAGRGELNNAATWDDFPNGRFGDFKSPAFG 368
[130][TOP]
>UniRef100_B7GB47 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Phaeodactylum tricornutum CCAP 1055/1
RepID=B7GB47_PHATR
Length = 376
Score = 95.5 bits (236), Expect = 2e-18
Identities = 46/83 (55%), Positives = 57/83 (68%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+M I Y GF +M FCKT+VP + +EAIKD+ AVKA+G+E GV MCR LLASG
Sbjct: 294 GLMCINAYAGFVKMAKFCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGH 353
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
V +H YTLNLEK +L+ LG
Sbjct: 354 VSVLHFYTLNLEKVVYGVLDALG 376
[131][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 92.4 bits (228), Expect = 2e-17
Identities = 42/101 (41%), Positives = 62/101 (61%), Gaps = 5/101 (4%)
Frame = +2
Query: 152 MCRQLLASGEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTAR 316
MC++L+ S V +H YT+NLE++ + ILE L L++ + LPWR +R
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRK-SLHPSR 59
Query: 317 AVEQVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
+ E +RP+FW R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 60 SKESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFG 100
[132][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 92.4 bits (228), Expect = 2e-17
Identities = 42/101 (41%), Positives = 62/101 (61%), Gaps = 5/101 (4%)
Frame = +2
Query: 152 MCRQLLASGEVPGVHMYTLNLEKSAVAILEQLGLVDTSRVQR-----PLPWRHVPAGTAR 316
MC++L+ S V +H YT+NLE++ + ILE L L++ + LPWR +R
Sbjct: 1 MCQKLIDSKVVSHLHFYTMNLERATIMILENLNLIEPVKDHEIIGGVDLPWRK-SLHPSR 59
Query: 317 AVEQVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
+ E +RP+FW R Y+ RT WD +P GRWG++RSPA+G
Sbjct: 60 SKESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFG 100
[133][TOP]
>UniRef100_UPI000194E904 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH), partial n=1 Tax=Taeniopygia guttata
RepID=UPI000194E904
Length = 345
Score = 89.7 bits (221), Expect = 1e-16
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI PI Y +++ K +VP EI D +E IKDND A++ YG+EL V MCR+LL SG
Sbjct: 257 GIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGM 316
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
V G+H YTLN E + +L++LGL
Sbjct: 317 VHGLHFYTLNREVATTEVLKRLGL 340
[134][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 89.7 bits (221), Expect = 1e-16
Identities = 61/187 (32%), Positives = 87/187 (46%), Gaps = 39/187 (20%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y F+R+ K VP I+ L+ I +D VK YG EL +M Q++ SG
Sbjct: 214 GIMPIQNYASFRRLVNLTKCPVPDSITSDLQPISSDDATVKRYGAELATKMVSQIIESGL 273
Query: 182 VPGVHMYTLNLEKSAVAILEQLG------------------LVDTSRVQRPLPWRHVPAG 307
VPGVH+ TLNLEKS IL+ LG + D + ++ +P + AG
Sbjct: 274 VPGVHLCTLNLEKSVRMILDNLGWSAASKTSEDEGLVKNKLIEDDGQARKGIP-INGKAG 332
Query: 308 TARAVEQVRPVFWSK----------------RPKDYVKR-----TQDWDSYPAGRWGNTR 424
TA++ + + S+ PK + WD +P GR+ + R
Sbjct: 333 TAQSPAKNLSISPSEANQLAQLGLTSTTLPPAPKTGLSAQGATGEDSWDEFPNGRFTDVR 392
Query: 425 SPAYGAL 445
SPAYG +
Sbjct: 393 SPAYGEI 399
[135][TOP]
>UniRef100_A9UZU5 Methylenetetrahydrofolate reductase n=1 Tax=Monosiga brevicollis
RepID=A9UZU5_MONBE
Length = 332
Score = 89.4 bits (220), Expect = 1e-16
Identities = 44/84 (52%), Positives = 58/84 (69%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIM I GGFKRMT FCK++ PA + A+EA D+ EA++ +E G ++CR L A+G
Sbjct: 244 GIMCIQNAGGFKRMTAFCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQAAG- 302
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLNLEK +AIL+ L L
Sbjct: 303 APGLHFYTLNLEKVTLAILDALNL 326
[136][TOP]
>UniRef100_B8BVS6 Methylenetetrahydrofolate reductase n=1 Tax=Thalassiosira
pseudonana CCMP1335 RepID=B8BVS6_THAPS
Length = 383
Score = 86.3 bits (212), Expect = 1e-15
Identities = 42/84 (50%), Positives = 58/84 (69%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+M I Y GFK+MT FCKT+VP + + ++AIKD+ +AVK +G+E G + R LL SG
Sbjct: 233 GLMCINAYPGFKKMTKFCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSG- 291
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
V +H YTLNLEK I ++LG+
Sbjct: 292 VKILHFYTLNLEKVVYGITDELGI 315
[137][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 82.8 bits (203), Expect = 1e-14
Identities = 38/82 (46%), Positives = 54/82 (65%), Gaps = 2/82 (2%)
Frame = +2
Query: 206 LNLEKSAVAILEQLGLVDTSR--VQRPLPWRHVPAGTARAVEQVRPVFWSKRPKDYVKRT 379
+NL ++ +LE+L + TS +++ LPW+ G R E VRP+FW R K Y+ RT
Sbjct: 1 MNLAQATRMVLEELNWMPTSERPLKQALPWKQ-SLGLGRREEDVRPIFWKGRNKSYILRT 59
Query: 380 QDWDSYPAGRWGNTRSPAYGAL 445
QDWD +P GRWG++RSPA+G L
Sbjct: 60 QDWDEFPNGRWGDSRSPAFGEL 81
[138][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 82.0 bits (201), Expect = 2e-14
Identities = 57/173 (32%), Positives = 79/173 (45%), Gaps = 27/173 (15%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI TY F R+T C TKVP+ + L IK++D+ VK YG++ V+ +L G
Sbjct: 210 GIMPIQTYATFARLTKLCGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIHRLRNEGG 269
Query: 182 VPGVHMYTLNLEKSAVAILEQL----GLVDTSRVQRPL--------------------PW 289
+ G H TLNLEKS +LE+L G+V VQ L P
Sbjct: 270 IQGFHFCTLNLEKSVQRVLEELKWRTGVVPA--VQNKLIADSPDALSQNTLDSNLLITPT 327
Query: 290 RHVPAGTARAVEQVRPVFWSKRP---KDYVKRTQDWDSYPAGRWGNTRSPAYG 439
T+ V P + + WD +P GR+G+ +SPA+G
Sbjct: 328 SATNVATSVLTTSVLGTVSRTLPEAGRGELNDAATWDDFPNGRFGDFKSPAFG 380
[139][TOP]
>UniRef100_B9XQY3 Methylenetetrahydrofolate reductase n=1 Tax=bacterium Ellin514
RepID=B9XQY3_9BACT
Length = 303
Score = 80.1 bits (196), Expect = 8e-14
Identities = 37/84 (44%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GI+PI++ G KR++ C K+P+ + LE + DNDEA AYGI+ C +LL G
Sbjct: 219 GILPILSAGQIKRISALCGAKLPSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREG- 277
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+HMYTLN S + +L+ L L
Sbjct: 278 APGLHMYTLNKAPSTIQVLKNLAL 301
[140][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 79.0 bits (193), Expect = 2e-13
Identities = 46/151 (30%), Positives = 69/151 (45%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y F+RM C P ++ + LE IK +D VK +GI L + M + +
Sbjct: 238 GIMPIQNYTMFRRMANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTG 297
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSKRPK 361
+ H+YTLNLEKSA +++ L VP +A
Sbjct: 298 IRAFHLYTLNLEKSATCVIKVLA--------------DVPDQSAS--------------- 328
Query: 362 DYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ + WD +P GR+ + RSPA+G + +
Sbjct: 329 --ISGSVTWDEFPNGRYTDARSPAFGEMDGY 357
[141][TOP]
>UniRef100_B4D0K5 Methylenetetrahydrofolate reductase n=1 Tax=Chthoniobacter flavus
Ellin428 RepID=B4D0K5_9BACT
Length = 297
Score = 78.6 bits (192), Expect = 2e-13
Identities = 40/86 (46%), Positives = 52/86 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+T G +R C K+PA+ L+ + +DEAV AYGIE C LL G
Sbjct: 212 GIMPILTAGQTRRFVSLCGAKLPAQFLRRLDELDGDDEAVAAYGIEYATEQCASLLEFG- 270
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD 259
VPG+H YTLN +S V I+ LGL++
Sbjct: 271 VPGLHFYTLNKARSTVQIVRNLGLLN 296
[142][TOP]
>UniRef100_Q0EWI5 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EWI5_9PROT
Length = 251
Score = 77.4 bits (189), Expect = 5e-13
Identities = 38/82 (46%), Positives = 53/82 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +PA + + ++ I+D+ EAVKA GIEL + CR+LL +G
Sbjct: 167 GIMPIGNYDQIVRFSSMCGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAG- 225
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
VPG+H YTLN ++ +AI QL
Sbjct: 226 VPGLHFYTLNKSEATIAIRNQL 247
[143][TOP]
>UniRef100_A4HQF9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania braziliensis
RepID=A4HQF9_LEIBR
Length = 309
Score = 75.9 bits (185), Expect = 2e-12
Identities = 35/83 (42%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
G++PI TY GF RM CKT+VP ++ +E +K+N EA+K YG+E V+M ++ ASG
Sbjct: 222 GLLPITTYAGFTRMVSLCKTRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGL 281
Query: 179 EVPGVHMYTLNLEKSAVAILEQL 247
+ +H YTLN +L++L
Sbjct: 282 DYHHLHFYTLNSSAQTFQVLKRL 304
[144][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 75.9 bits (185), Expect = 2e-12
Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEA-IKDNDEAVKAYGIELGVRMCRQLL--A 172
G+MPI TY F+R T +P + ++ +D+ VK G++L + + Q+
Sbjct: 215 GLMPINTYQLFQRATNLSHASIPPAVGQLFPPDVRHDDDKVKDIGVKLMIDIVDQIYNET 274
Query: 173 SGEVPGVHMYTLNLEKSAVAILEQLGLVD-----TSRVQRPLPWRHVPAGTARAVEQVRP 337
GEV G H YTLNLEKS I+++ L+ +SR + + +Q +
Sbjct: 275 HGEVNGYHFYTLNLEKSVAQIVDKSSLLSPRLTVSSRFENAI--ESSSEDEKEQNQQTKT 332
Query: 338 VFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ + + + WD +P GR+G++RSPAYG + +
Sbjct: 333 IIAISSGEGTMGKEATWDDFPNGRYGDSRSPAYGEIDGY 371
[145][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 74.7 bits (182), Expect = 4e-12
Identities = 50/171 (29%), Positives = 80/171 (46%), Gaps = 20/171 (11%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQL--LAS 175
G+MPI +Y R+T K+P EI +EA K +DE VK G+++ + + +++
Sbjct: 225 GLMPIQSYHTLTRVTKLSHAKIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKIST 284
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGLVDTSR---VQRPLPWRHVPAGTARAVEQVRPV-- 340
G H YTLNLEKS ILE+ L+ S L + + + V + +
Sbjct: 285 PGHRGFHFYTLNLEKSVSFILERCNLIPPSSEAPSDNELEFELAVSDRSSTVHETSALTA 344
Query: 341 -FWSKRPKD------------YVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
+ + P + + R WD +P GRWG+ RSPA+G + +
Sbjct: 345 GYPALNPPNRNTTLQISEGLGSLGREATWDDFPNGRWGDARSPAFGEIDGY 395
[146][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 73.6 bits (179), Expect = 8e-12
Identities = 49/163 (30%), Positives = 77/163 (47%), Gaps = 12/163 (7%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI TY F R T VPA +++ L + +D+ VK G+++ ++ + A
Sbjct: 216 GLMPITTYKVFTRATKLSHASVPAAVAEQLSSAAVDDDQVKKIGVDVLSQLVADVSARSA 275
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLV--DTSRVQRPL----PWRH------VPAGTARAVE 325
G H YTLNLE++ AI+E + +R+ R P+ AG +V
Sbjct: 276 ARGFHFYTLNLERAVAAIVESCPELRGSAARLSRSRASSDPFESDSETSAPNAGKVESVP 335
Query: 326 QVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
P+ +R V WD +P GR+G+ SPAYG + +
Sbjct: 336 DSVPLVRDRR----VTLAATWDDFPNGRFGDASSPAYGEIDGY 374
[147][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 73.2 bits (178), Expect = 1e-11
Identities = 54/202 (26%), Positives = 86/202 (42%), Gaps = 29/202 (14%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MP+ TY F R T +P I E IK++D+AVK G++L + ++
Sbjct: 217 GLMPVTTYKVFTRATKLSHATIPRPILHEFETIKNDDDAVKQLGVDLICDIIDRIDEHTN 276
Query: 182 VPGVHMYTLNLEKSAVAILEQL---------------------GLVDTSRVQRPLPWR-- 292
+ G H YTLNLEK+ +I+ Q + S + P +R
Sbjct: 277 IKGYHFYTLNLEKAVASIMNQSQVLRGVLEGPSTSSEISKNEDAIASDSEDESPKHFRRR 336
Query: 293 ----HVPAGTARAVEQ--VRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYGALSDH 454
V G+ Q + + R K + + WD +P GR+G++ SPAYG + +
Sbjct: 337 SSVNEVARGSLSFHRQKDKKSIVDISRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGY 396
Query: 455 QFMRRHRNGEARREKARADWGA 520
+ N +A A WG+
Sbjct: 397 GPSLKIHNA----SEAIAKWGS 414
[148][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 72.4 bits (176), Expect = 2e-11
Identities = 52/185 (28%), Positives = 82/185 (44%), Gaps = 35/185 (18%)
Frame = +2
Query: 5 IMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGEV 184
IMP+ + +RM C +P ++ +LE ++ +DE VKA G++ +M + +L + +
Sbjct: 222 IMPVQSLTTLRRMARLCNCVIPHDLMQSLEEVRTDDEKVKAIGVKHVAQMIKDILKNTDT 281
Query: 185 PGVHMYTLNLEKSAVAILEQLGLVDT--------------------SRVQRPLPWRHVPA 304
G H TLNLEKS IL + GL + +RV P H+P+
Sbjct: 282 RGFHFCTLNLEKSVARILNESGLYERRLTALKAVVNNQKENVADVHNRVVIPKK-DHLPS 340
Query: 305 G---------------TARAVEQVRPVFWSKRPKDYVKRTQDWDSYPAGRWGNTRSPAYG 439
TA E+ + S+ + R WD Y GR+G+ RSPAYG
Sbjct: 341 AFEGLYIRADDKQFTRTAEFFEKQASISVSE-GTGALGREATWDDYTNGRFGDPRSPAYG 399
Query: 440 ALSDH 454
+ +
Sbjct: 400 NIDGY 404
[149][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 72.0 bits (175), Expect = 2e-11
Identities = 38/86 (44%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +2
Query: 5 IMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLL--ASG 178
IMPI +YG KRMT C VP+ + L A K +DEA+K G+E V M ++++ G
Sbjct: 222 IMPIQSYGSLKRMTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQG 281
Query: 179 EVPGVHMYTLNLEKSAVAILEQLGLV 256
V G H TLNLE+S IL+ GL+
Sbjct: 282 RVHGFHFCTLNLERSVALILKNSGLL 307
[150][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 71.6 bits (174), Expect = 3e-11
Identities = 58/206 (28%), Positives = 86/206 (41%), Gaps = 55/206 (26%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIEL---GVRMCRQLLA 172
G+MPI +Y R T K+P +I LEA+K +D+AVK G+++ V +++
Sbjct: 225 GLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPC 284
Query: 173 SGEVPGVHMYTLNLEKSAVAILEQLGL-----------VDTSRVQRPLPWRH-------- 295
G G H YTLNLEK+ I+E+ GL VD P +H
Sbjct: 285 PG-FRGFHFYTLNLEKTVSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRA 343
Query: 296 -----------------VPA-GTARAVEQVRPVFWSKRP---------------KDYVKR 376
VP+ G++RA P + P + + R
Sbjct: 344 SSVNSLPHNRVIVDRLQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGR 403
Query: 377 TQDWDSYPAGRWGNTRSPAYGALSDH 454
WD +P GRWG+ RSPA+G + +
Sbjct: 404 EATWDDFPNGRWGDARSPAFGEIDGY 429
[151][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 71.6 bits (174), Expect = 3e-11
Identities = 58/206 (28%), Positives = 86/206 (41%), Gaps = 55/206 (26%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIEL---GVRMCRQLLA 172
G+MPI +Y R T K+P +I LEA+K +D+AVK G+++ V +++
Sbjct: 225 GLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPC 284
Query: 173 SGEVPGVHMYTLNLEKSAVAILEQLGL-----------VDTSRVQRPLPWRH-------- 295
G G H YTLNLEK+ I+E+ GL VD P +H
Sbjct: 285 PG-FRGFHFYTLNLEKTVSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRA 343
Query: 296 -----------------VPA-GTARAVEQVRPVFWSKRP---------------KDYVKR 376
VP+ G++RA P + P + + R
Sbjct: 344 SSVNSLPHNRVIVDRLQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGR 403
Query: 377 TQDWDSYPAGRWGNTRSPAYGALSDH 454
WD +P GRWG+ RSPA+G + +
Sbjct: 404 EATWDDFPNGRWGDARSPAFGEIDGY 429
[152][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 71.6 bits (174), Expect = 3e-11
Identities = 60/206 (29%), Positives = 88/206 (42%), Gaps = 55/206 (26%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIEL---GVRMCRQLLA 172
G+MPI +Y R T K+P +I LEA+K +D+AVK G+++ V +++
Sbjct: 252 GLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPC 311
Query: 173 SGEVPGVHMYTLNLEKSAVAILEQLGLV-----DTSRV-------------QRPLPWR-- 292
G G H YTLNLEK+ I+E+ GL+ DT V R L R
Sbjct: 312 PG-FRGFHFYTLNLEKTVSFIIERCGLIPDYPEDTDAVVDDDYTTAPTGAQNRSLSRRRA 370
Query: 293 ----------------HVPA-GTARAVEQVRPVFWSKRP---------------KDYVKR 376
VP+ G++RA P + P + + R
Sbjct: 371 SSVNSLPHNRVIVDRLQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGR 430
Query: 377 TQDWDSYPAGRWGNTRSPAYGALSDH 454
WD +P GRWG+ RSPA+G + +
Sbjct: 431 EATWDDFPNGRWGDARSPAFGEIDGY 456
[153][TOP]
>UniRef100_Q4Q0B9 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania major
RepID=Q4Q0B9_LEIMA
Length = 309
Score = 70.5 bits (171), Expect = 7e-11
Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
G++PI TY GF RM CKT VP+++ +E +K+N + +K YG+E V+M + ASG
Sbjct: 222 GLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRASGL 281
Query: 179 EVPGVHMYTLNLEKSAVAILEQL 247
+ +H YTLN IL++L
Sbjct: 282 DYHHLHFYTLNNSAQIFKILKRL 304
[154][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 70.5 bits (171), Expect = 7e-11
Identities = 55/208 (26%), Positives = 85/208 (40%), Gaps = 57/208 (27%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLL-ASG 178
G+MPI +Y KR T K+P + L+A+K +DE VK G+ + M ++
Sbjct: 227 GLMPIQSYQMIKRTTKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKS 286
Query: 179 EVP---GVHMYTLNLEKSAVAILEQLGLV-------DTSRVQRPLPWRHVPAGT--ARAV 322
P G H YTLNLEK+ I E+ L+ D S + +P + + R++
Sbjct: 287 RTPGPRGFHFYTLNLEKAVAFIAERTNLIPPGTPDEDESAILPDIPQLRINGSSVPTRSI 346
Query: 323 EQV-------------RPVFWSKRPK--DY-----------------------------V 370
+ + R + ++RP DY +
Sbjct: 347 QDLSTRKGSIGSDPRDRVIVANQRPSHPDYEASPSEAGLPAEPVNTRANTLAISEGEGVL 406
Query: 371 KRTQDWDSYPAGRWGNTRSPAYGALSDH 454
R WD +P GRWG+ RSPAYG + +
Sbjct: 407 GREATWDDFPNGRWGDARSPAYGQIDGY 434
[155][TOP]
>UniRef100_UPI0001699FF2 5,10-methylenetetrahydrofolate reductase n=1 Tax=Endoriftia
persephone 'Hot96_1+Hot96_2' RepID=UPI0001699FF2
Length = 120
Score = 70.1 bits (170), Expect = 9e-11
Identities = 32/84 (38%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C T++P I LE D+ E+++A+G+E+ +CR+LL G
Sbjct: 38 GIMPITNYSSLVRFSDACGTEIPRWIRKRLEGFSDDLESIRAFGLEVVTELCRRLLEGG- 96
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + + + ++LGL
Sbjct: 97 APGLHFYTMNQSEPTLRLCDRLGL 120
[156][TOP]
>UniRef100_Q0VL81 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax borkumensis
SK2 RepID=Q0VL81_ALCBS
Length = 275
Score = 70.1 bits (170), Expect = 9e-11
Identities = 36/84 (42%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ R + C VP + L IKD+D AVKA+G E+ R+C +LLA G
Sbjct: 193 GIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVVTRLCERLLAMG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + IL+ LG+
Sbjct: 252 APGLHFYTMNQAGPNLRILDNLGM 275
[157][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 70.1 bits (170), Expect = 9e-11
Identities = 55/194 (28%), Positives = 81/194 (41%), Gaps = 43/194 (22%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI TY F R +P EIS ++ + +D+AVKA G+E+ + ++
Sbjct: 217 GLMPITTYKVFNRAAKLSHATIPREISQQVDKVSHDDDAVKALGVEILSNIIDRIDKETN 276
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQRPL------PWRHVPA-----------GT 310
+ G H YTLNLEK+ +IL D S V RP+ H A T
Sbjct: 277 IKGYHFYTLNLEKAVASIL------DKSDVLRPILEGPSTVMEHDDAIASDSDDDEDMNT 330
Query: 311 ARAVEQVR--------PVFWSK------------------RPKDYVKRTQDWDSYPAGRW 412
+AV R + SK K + + WD +P GR+
Sbjct: 331 GQAVSVTRRRSSINDNSLMGSKALIGKALLKDKKTLVDISTGKGALGKDATWDDFPNGRF 390
Query: 413 GNTRSPAYGALSDH 454
G++ SPAYG + +
Sbjct: 391 GDSNSPAYGEIDGY 404
[158][TOP]
>UniRef100_B4X3B0 Methylenetetrahydrofolate reductase n=1 Tax=Alcanivorax sp. DG881
RepID=B4X3B0_9GAMM
Length = 275
Score = 69.7 bits (169), Expect = 1e-10
Identities = 36/84 (42%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ R + C VP + L IKD+D AVKA+G E+ R+C +LLA G
Sbjct: 193 GIMPILNVANLLRFSSTCGADVPRWLQSKLNDIKDDDVAVKAFGEEVVTRLCERLLAMG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + IL+ LG+
Sbjct: 252 APGLHFYTMNQAGPNLRILDNLGM 275
[159][TOP]
>UniRef100_A6C2T8 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces maris DSM
8797 RepID=A6C2T8_9PLAN
Length = 297
Score = 69.3 bits (168), Expect = 1e-10
Identities = 34/87 (39%), Positives = 50/87 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y +R+ C ++ PA++ LEA +D+ EA G+E +R C QL+ G
Sbjct: 206 GIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQDDLEAQFEIGVEYAIRQCEQLIKEG- 264
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT 262
VPG+H Y LN ++ I + LG +T
Sbjct: 265 VPGIHFYVLNRSQACKRIFDALGFPET 291
[160][TOP]
>UniRef100_A3JC11 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter sp. ELB17
RepID=A3JC11_9ALTE
Length = 318
Score = 69.3 bits (168), Expect = 1e-10
Identities = 33/90 (36%), Positives = 54/90 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ + R + C ++P I LEA D+ E+++ +G E+ RMC +LL +G
Sbjct: 228 GIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKAG- 286
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRV 271
PG+H YTLN + ++ I + LGL + ++
Sbjct: 287 APGLHFYTLNQVEPSLGIWKNLGLGEREKI 316
[161][TOP]
>UniRef100_Q2SLT5 Methylenetetrahydrofolate reductase n=1 Tax=Hahella chejuensis KCTC
2396 RepID=Q2SLT5_HAHCH
Length = 287
Score = 68.9 bits (167), Expect = 2e-10
Identities = 32/86 (37%), Positives = 51/86 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P + LEA D+ +++ +G E+ R+C +LLA+G
Sbjct: 199 GIMPITNYSNLARFSDMCGAEIPRWVRKQLEAYGDDSASIRKFGEEVVTRLCERLLAAG- 257
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD 259
PG+H YTLN + ++A+ + L L D
Sbjct: 258 APGIHFYTLNQAEPSLAVWDNLNLGD 283
[162][TOP]
>UniRef100_B3PGF0 Methylenetetrahydrofolate reductase n=1 Tax=Cellvibrio japonicus
Ueda107 RepID=B3PGF0_CELJU
Length = 282
Score = 68.9 bits (167), Expect = 2e-10
Identities = 31/87 (35%), Positives = 52/87 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ Y R + C ++P + ALE D++E+++A+G++L +C ++L E
Sbjct: 196 GIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEESLRAFGVDLVTELC-EVLLENE 254
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT 262
PG+H YT+N + I+ LGL+ T
Sbjct: 255 APGLHFYTMNQTEPTAQIVRNLGLIPT 281
[163][TOP]
>UniRef100_B8KLD1 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR5-3 RepID=B8KLD1_9GAMM
Length = 278
Score = 68.9 bits (167), Expect = 2e-10
Identities = 32/84 (38%), Positives = 50/84 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P IS LE D+ ++++A+GI++ ++C+ LL SG
Sbjct: 196 GIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQDSIRAFGIDVVTQLCQTLLESG- 254
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + + I LGL
Sbjct: 255 APGIHFYTMNQTQPTLQICRNLGL 278
[164][TOP]
>UniRef100_A4IC95 Methylenetetrahydrofolate reductase n=1 Tax=Leishmania infantum
RepID=A4IC95_LEIIN
Length = 309
Score = 68.9 bits (167), Expect = 2e-10
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG- 178
G++PI TY GF RM CKT VP+++ +E +K+N + +K YG+E V+M + SG
Sbjct: 222 GLLPITTYAGFVRMVSLCKTSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGL 281
Query: 179 EVPGVHMYTLNLEKSAVAILEQL 247
+ +H YTLN +L++L
Sbjct: 282 DYHHLHFYTLNNSAQTFKVLKRL 304
[165][TOP]
>UniRef100_Q476T6 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha
JMP134 RepID=Q476T6_RALEJ
Length = 276
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/84 (39%), Positives = 53/84 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++VP ++ LE+ D+ E+++A+G+++ +C +LLA G
Sbjct: 194 GIMPITNYSQLMRFSDMCGSEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI ++L L
Sbjct: 253 VPGLHFYTLNAAGATKAIWQRLKL 276
[166][TOP]
>UniRef100_B8KU68 Methylenetetrahydrofolate reductase n=1 Tax=gamma proteobacterium
NOR51-B RepID=B8KU68_9GAMM
Length = 216
Score = 68.6 bits (166), Expect = 3e-10
Identities = 33/87 (37%), Positives = 50/87 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ + +R G C ++P I + D+ E+V+ +GIE+ ++C L SG
Sbjct: 130 GIMPIVNFTNLERFAGSCGAEIPRWIRQRVAGFGDDQESVRKFGIEVVTQICATLQESG- 188
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT 262
PGVH YT+N + + I LGL+DT
Sbjct: 189 APGVHFYTMNQVEPTLTIAANLGLIDT 215
[167][TOP]
>UniRef100_A4A9E4 Methylenetetrahydrofolate reductase n=1 Tax=Congregibacter
litoralis KT71 RepID=A4A9E4_9GAMM
Length = 278
Score = 68.6 bits (166), Expect = 3e-10
Identities = 32/84 (38%), Positives = 50/84 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P IS LE D+ E+++A+GI++ ++C+ LL S +
Sbjct: 196 GIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQESIRAFGIDVVTQLCQTLLES-D 254
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + + I LGL
Sbjct: 255 APGIHFYTMNQAQPTLQICRNLGL 278
[168][TOP]
>UniRef100_B2AGG4 Methylenetetrahydrofolate reductase n=1 Tax=Cupriavidus taiwanensis
RepID=B2AGG4_CUPTR
Length = 276
Score = 68.2 bits (165), Expect = 3e-10
Identities = 33/84 (39%), Positives = 53/84 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +VP ++ LE+ D+ E+++A+G+++ +C +LLA+G
Sbjct: 194 GIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI ++L L
Sbjct: 253 VPGLHFYTLNAAGATKAIWQRLKL 276
[169][TOP]
>UniRef100_A1U549 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter aquaeolei
VT8 RepID=A1U549_MARAV
Length = 289
Score = 68.2 bits (165), Expect = 3e-10
Identities = 31/90 (34%), Positives = 55/90 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ + R + C ++P I LEA D+ ++++ +G E+ MC++LL +G
Sbjct: 199 GIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRKFGEEVVTEMCQKLLKAG- 257
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRV 271
PG+H YTLN + +++I + LG+ D ++
Sbjct: 258 APGLHFYTLNQAEPSLSIWKNLGISDREKI 287
[170][TOP]
>UniRef100_A6EZ72 Methylenetetrahydrofolate reductase n=1 Tax=Marinobacter algicola
DG893 RepID=A6EZ72_9ALTE
Length = 289
Score = 68.2 bits (165), Expect = 3e-10
Identities = 31/90 (34%), Positives = 55/90 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ + R + C ++P I LEA D+ ++++ +G E+ MC +LLA+G
Sbjct: 199 GIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRKFGEEVVTEMCAKLLAAG- 257
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRV 271
PG+H YTLN + +++I + LG+ + ++
Sbjct: 258 APGLHFYTLNQAEPSLSIWKNLGIGEREKI 287
[171][TOP]
>UniRef100_B4SJY7 Methylenetetrahydrofolate reductase n=1 Tax=Stenotrophomonas
maltophilia R551-3 RepID=B4SJY7_STRM5
Length = 275
Score = 67.8 bits (164), Expect = 4e-10
Identities = 32/82 (39%), Positives = 52/82 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P IS ++A D+ E+V+A+G E+ R+C++L+ G
Sbjct: 193 GIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVVARLCQRLIEDG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
PG+H YTLNL K ++L+ L
Sbjct: 252 APGLHFYTLNLAKPTTSVLKLL 273
[172][TOP]
>UniRef100_C7QA95 5,10-methylenetetrahydrofolate reductase n=1 Tax=Catenulispora
acidiphila DSM 44928 RepID=C7QA95_CATAD
Length = 315
Score = 67.4 bits (163), Expect = 6e-10
Identities = 33/84 (39%), Positives = 50/84 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MP+ KR+TG PA++ +L A++ + AV+A G++ RMC +LLA G
Sbjct: 219 GVMPVTNVAQIKRITGLTGQAFPADLERSLMAVEGDKAAVRAVGVDWTTRMCERLLAEG- 277
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H TLN+ + + I LGL
Sbjct: 278 VPGLHFITLNMSTATLEIYRNLGL 301
[173][TOP]
>UniRef100_B5WH86 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia sp. H160
RepID=B5WH86_9BURK
Length = 276
Score = 67.4 bits (163), Expect = 6e-10
Identities = 33/84 (39%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP I+ LE+ D+ E+++A+G+E+ +C Q L +
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLEVVTNLC-QRLVDAK 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI E+LG+
Sbjct: 253 VPGLHFYTLNTAAATKAICERLGV 276
[174][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 67.4 bits (163), Expect = 6e-10
Identities = 54/184 (29%), Positives = 78/184 (42%), Gaps = 33/184 (17%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKD-NDEAVKAYGIELGVRMCRQLLASG 178
G+MPI TY F R VP I D ++A+ ND+ VK G+E+ + +
Sbjct: 218 GLMPINTYTSFVRAARLSHASVPPAILDRIQAVPTGNDQQVKDIGVEVVSDIVNDVYTKT 277
Query: 179 E--VPGVHMYTLNLEKSAVAILEQLGLV----------------DTSRVQRPLPWRHVPA 304
V G H YTLNLE+S ILE+ G + T+ + PL R
Sbjct: 278 NKTVRGFHFYTLNLERSVARILERSGFLTIEEDCAVEEATGSTASTTPNKTPLRRRSSAT 337
Query: 305 GTARAVEQVR--PVFWSKRP------------KDYVKRTQDWDSYPAGRWGNTRSPAYGA 442
R V+ R P + P + V R WD +P GR+G++ SPA+G
Sbjct: 338 HRNRVVDDARHHPDAPKEEPDLTTLALAIASGEGAVGREAVWDDFPNGRFGDSSSPAFGE 397
Query: 443 LSDH 454
+ +
Sbjct: 398 IDGY 401
[175][TOP]
>UniRef100_Q1LS18 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia metallidurans
CH34 RepID=Q1LS18_RALME
Length = 276
Score = 67.0 bits (162), Expect = 7e-10
Identities = 33/84 (39%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +VP ++ LE+ D+ EA++A+G+++ +C +LL +G
Sbjct: 194 GIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDVVTDLCTRLLEAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI ++L L
Sbjct: 253 VPGLHFYTLNAAGATKAIWQRLKL 276
[176][TOP]
>UniRef100_B1J2Y7 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida W619
RepID=B1J2Y7_PSEPW
Length = 281
Score = 67.0 bits (162), Expect = 7e-10
Identities = 35/84 (41%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ +++A+G E+ RMC QLL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN ++++AI L L
Sbjct: 256 APGLHFYTLNQAEASLAIWNNLKL 279
[177][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 67.0 bits (162), Expect = 7e-10
Identities = 55/209 (26%), Positives = 84/209 (40%), Gaps = 58/209 (27%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQL--LAS 175
G+MPI +Y R+T VP EI +E K +DEAVK G+++ + ++ ++
Sbjct: 225 GLMPIQSYSRLTRITKLSHACVPPEILARIEKCKMDDEAVKRVGVDVVSELVDEIKTISC 284
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGLVDTS-------RVQRPLPWRH----VPAGTARAV 322
G+H +TLNLEKS ILE+ L+ +S + + H PAG A V
Sbjct: 285 PGPRGLHFFTLNLEKSVSFILERCNLIPSSSEPSSDTESESAVYAMHKNLTAPAGKAAFV 344
Query: 323 EQVRPVFWSKRPKDYV-------------------------------------------- 370
+ R + +P + V
Sbjct: 345 SRRRASSLNSQPYNRVIIDRADMSSQSSTTHETSAQGAGMPALNPPPRNTTLLISEGMGA 404
Query: 371 -KRTQDWDSYPAGRWGNTRSPAYGALSDH 454
R WD +P GRWG+ RSPA+G + +
Sbjct: 405 LGREATWDDFPNGRWGDARSPAFGEIDGY 433
[178][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 67.0 bits (162), Expect = 7e-10
Identities = 52/206 (25%), Positives = 84/206 (40%), Gaps = 55/206 (26%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQL--LAS 175
G+MPI +Y R+T +VP I LEA++ +D+AVK G+++ + + + +
Sbjct: 225 GLMPIHSYKILTRVTKLSHVQVPPHILSKLEAVRHDDDAVKRIGVDVITNLVDGIRKIPN 284
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGLV----DTSRVQRPLPWRHVPAG------TARAVE 325
G H YTLNLEK+ I+E+ GL+ + S + VP+G T R
Sbjct: 285 PGFRGFHFYTLNLEKTVSFIIERCGLIPDDAENSAAVDEDDYATVPSGAQLRALTRRRAS 344
Query: 326 QVRPVFWSKRPKDYVKRTQD---------------------------------------- 385
V ++ D +++ D
Sbjct: 345 SVHSQAHNRVIVDKLQKPSDGSSRASTTHEALANSAGMPAMAPDRNTTLQISEGLGALGR 404
Query: 386 ---WDSYPAGRWGNTRSPAYGALSDH 454
WD +P GRWG+ RSPA+G + +
Sbjct: 405 EATWDDFPNGRWGDARSPAFGEIDGY 430
[179][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 66.6 bits (161), Expect = 1e-09
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 44/195 (22%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQL--LAS 175
G+MPI TY F R + + +P EI L+ +D AVK+ GI + M Q+ ++
Sbjct: 216 GLMPITTYKVFTRASKLSHSSIPHEIESQLQNTSSDDNAVKSIGIRIITDMVDQINNRSN 275
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGLV-------------------DTSRVQRP------ 280
G + G H Y LNLEK+ ++L+Q ++ D ++ P
Sbjct: 276 GAIRGYHFYCLNLEKAVASVLDQSAVLRPIMEAPTNTISHDDAVASDDEDIEMPPKKGRR 335
Query: 281 -----------------LPWRHVPAGTARAVEQVRPVFWSKRPKDYVKRTQDWDSYPAGR 409
+ H + + R + K + + WD +P GR
Sbjct: 336 RSSIINENEVAAPGFAAVGMGHKASANKALLSDKRTLVDISTGKGALGKDATWDDFPNGR 395
Query: 410 WGNTRSPAYGALSDH 454
+G++ SPAYG + +
Sbjct: 396 FGDSNSPAYGEIDGY 410
[180][TOP]
>UniRef100_Q2STU2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis E264 RepID=Q2STU2_BURTA
Length = 276
Score = 66.6 bits (161), Expect = 1e-09
Identities = 32/84 (38%), Positives = 53/84 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP I+ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADVVTGLCRRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + A+ E+LGL
Sbjct: 253 VPGLHFYTLNGAAATKAVCERLGL 276
[181][TOP]
>UniRef100_Q0KF23 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia eutropha H16
RepID=Q0KF23_RALEH
Length = 276
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/84 (39%), Positives = 53/84 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +VP ++ LE+ D+ E+++A+G+++ +C +LLA+G
Sbjct: 194 GIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLDVVTALCERLLAAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI ++L L
Sbjct: 253 VPGLHFYTLNAAGATKAIWQRLKL 276
[182][TOP]
>UniRef100_B6J3R7 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
CbuG_Q212 RepID=B6J3R7_COXB2
Length = 290
Score = 66.6 bits (161), Expect = 1e-09
Identities = 34/91 (37%), Positives = 54/91 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C T++P + LE+ K++ ++KAYG+E+ ++C L+A G
Sbjct: 197 GIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ 274
VPG+H YTLN + I+E L + + R Q
Sbjct: 256 VPGLHFYTLNQCEPTQTIIENLQSITSFREQ 286
[183][TOP]
>UniRef100_B2JIP2 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia phymatum
STM815 RepID=B2JIP2_BURP8
Length = 276
Score = 66.6 bits (161), Expect = 1e-09
Identities = 31/84 (36%), Positives = 54/84 (64%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G+++ +CR+L+ +
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDVVTNLCRRLV-DAK 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN ++ AI E+LG+
Sbjct: 253 VPGLHFYTLNGAAASKAICERLGV 276
[184][TOP]
>UniRef100_B0RV90 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. campestris str. B100 RepID=B0RV90_XANCB
Length = 285
Score = 66.6 bits (161), Expect = 1e-09
Identities = 32/83 (38%), Positives = 50/83 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I ++A D+ +AV+A+G E+ +C +L+A G
Sbjct: 203 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAEVVAGLCERLIAGG- 261
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
VP +H YTLNL K +L+ LG
Sbjct: 262 VPALHFYTLNLAKPTTQVLQLLG 284
[185][TOP]
>UniRef100_A9N9C8 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=A9N9C8_COXBR
Length = 290
Score = 66.6 bits (161), Expect = 1e-09
Identities = 34/91 (37%), Positives = 54/91 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C T++P + LE+ K++ ++KAYG+E+ ++C L+A G
Sbjct: 197 GIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ 274
VPG+H YTLN + I+E L + + R Q
Sbjct: 256 VPGLHFYTLNQCEPTQTIIENLQSITSFREQ 286
[186][TOP]
>UniRef100_A4VRF8 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas stutzeri
A1501 RepID=A4VRF8_PSEU5
Length = 283
Score = 66.6 bits (161), Expect = 1e-09
Identities = 33/84 (39%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P + LEA D+ ++++A+G ++ MC++LLA G
Sbjct: 199 GIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAGG- 257
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI LGL
Sbjct: 258 APGLHFYTLNQAEPSLAIWNNLGL 281
[187][TOP]
>UniRef100_Q6J6A1 Methylenetetrahydrofolate reductase n=1 Tax=Collimonas fungivorans
RepID=Q6J6A1_9BURK
Length = 284
Score = 66.6 bits (161), Expect = 1e-09
Identities = 31/84 (36%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C T++P I L + D+ ++++A+G+++ ++C +LLA G
Sbjct: 202 GIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDSIRAFGLDVVTQLCERLLAGG- 260
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + +AI ++L L
Sbjct: 261 APGLHFYTLNQSPATIAIWQRLKL 284
[188][TOP]
>UniRef100_B6J6H7 Methylenetetrahydrofolate reductase n=2 Tax=Coxiella burnetii
RepID=B6J6H7_COXB1
Length = 290
Score = 66.6 bits (161), Expect = 1e-09
Identities = 34/91 (37%), Positives = 54/91 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C T++P + LE+ K++ ++KAYG+E+ ++C L+A G
Sbjct: 197 GIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ 274
VPG+H YTLN + I+E L + + R Q
Sbjct: 256 VPGLHFYTLNQCEPTQTIIENLQSITSFREQ 286
[189][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 66.6 bits (161), Expect = 1e-09
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 44/195 (22%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQL--LAS 175
G+MPI TY F R + + +P EI L+ +D AVK+ GI + M Q+ ++
Sbjct: 216 GLMPITTYKVFTRASKLSHSSIPHEIESQLQNTSSDDNAVKSIGIRIITDMVDQINNRSN 275
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGLV-------------------DTSRVQRP------ 280
G + G H Y LNLEK+ ++L+Q ++ D ++ P
Sbjct: 276 GAIRGYHFYCLNLEKAVASVLDQSAVLRPIMEAPTNTISHDDAVASDDEDIEMPPKKGRR 335
Query: 281 -----------------LPWRHVPAGTARAVEQVRPVFWSKRPKDYVKRTQDWDSYPAGR 409
+ H + + R + K + + WD +P GR
Sbjct: 336 RSSIINENEVAAPGFAAVGMGHKASANKALLSDKRTLVDISTGKGALGKDATWDDFPNGR 395
Query: 410 WGNTRSPAYGALSDH 454
+G++ SPAYG + +
Sbjct: 396 FGDSNSPAYGEIDGY 410
[190][TOP]
>UniRef100_Q88D51 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida
KT2440 RepID=Q88D51_PSEPK
Length = 295
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ +++A+G E+ RMC QLL G
Sbjct: 211 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGG- 269
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI L L
Sbjct: 270 APGLHFYTLNQAEPSLAIWNNLKL 293
[191][TOP]
>UniRef100_Q1I3W4 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas entomophila
L48 RepID=Q1I3W4_PSEE4
Length = 281
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ +++A+G E+ RMC QLL G
Sbjct: 197 GIMPITNYNKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI L L
Sbjct: 256 APGLHFYTLNQAEPSLAIWNNLKL 279
[192][TOP]
>UniRef100_B2FPB5 Methylenetetrahydrofolate reductase n=1 Tax=Stenotrophomonas
maltophilia K279a RepID=B2FPB5_STRMK
Length = 275
Score = 66.2 bits (160), Expect = 1e-09
Identities = 31/82 (37%), Positives = 51/82 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I ++A D+ E+V+A+G E+ R+C++L+ G
Sbjct: 193 GIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVVARLCQRLIEGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
PG+H YTLNL K ++L+ L
Sbjct: 252 APGLHFYTLNLAKPTTSVLKLL 273
[193][TOP]
>UniRef100_B0KM01 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida GB-1
RepID=B0KM01_PSEPG
Length = 281
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ +++A+G E+ RMC QLL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI L L
Sbjct: 256 APGLHFYTLNQAEPSLAIWNNLKL 279
[194][TOP]
>UniRef100_A5WA10 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas putida F1
RepID=A5WA10_PSEP1
Length = 281
Score = 66.2 bits (160), Expect = 1e-09
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ +++A+G E+ RMC QLL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI L L
Sbjct: 256 APGLHFYTLNQAEPSLAIWNNLKL 279
[195][TOP]
>UniRef100_C7RKF7 5,10-methylenetetrahydrofolate reductase n=1 Tax=Candidatus
Accumulibacter phosphatis clade IIA str. UW-1
RepID=C7RKF7_9PROT
Length = 279
Score = 66.2 bits (160), Expect = 1e-09
Identities = 31/84 (36%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI +Y R + C ++P I LE+ D+ +++A+G+++ ++C +LLASG
Sbjct: 196 GIMPISSYSSLARFSDNCGAEIPRWIRKKLESYGDDSASIRAFGLDVVTQLCEKLLASG- 254
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++LGL
Sbjct: 255 APGLHFYTLNQASLTSTLWQRLGL 278
[196][TOP]
>UniRef100_C5V644 Methylenetetrahydrofolate reductase n=1 Tax=Gallionella ferruginea
ES-2 RepID=C5V644_9PROT
Length = 275
Score = 66.2 bits (160), Expect = 1e-09
Identities = 32/82 (39%), Positives = 50/82 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ Y R + C ++P + +E D++E+V+A+G ++ MC +LLA G
Sbjct: 194 GIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRDIVTAMCEKLLAGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
PG+H YTLN +AI+E+L
Sbjct: 253 APGLHFYTLNQAAPCMAIVERL 274
[197][TOP]
>UniRef100_B8L0Q9 Methylenetetrahydrofolate reductase n=1 Tax=Stenotrophomonas sp.
SKA14 RepID=B8L0Q9_9GAMM
Length = 285
Score = 65.9 bits (159), Expect = 2e-09
Identities = 31/84 (36%), Positives = 53/84 (63%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P IS ++A D+ ++V+A+G E+ ++C++L+ G
Sbjct: 203 GIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDVDSVRAFGTEVVAKLCQRLIEGG- 261
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLNL K ++L+ L L
Sbjct: 262 APGLHFYTLNLAKPTTSVLKLLQL 285
[198][TOP]
>UniRef100_Q4UQY4 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas campestris
pv. campestris RepID=Q4UQY4_XANC8
Length = 275
Score = 65.5 bits (158), Expect = 2e-09
Identities = 31/83 (37%), Positives = 50/83 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G E+ +C +L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAGLCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
VP +H YTLNL K +L+ LG
Sbjct: 252 VPALHFYTLNLAKPTTQVLQLLG 274
[199][TOP]
>UniRef100_Q1R0K0 Methylenetetrahydrofolate reductase n=1 Tax=Chromohalobacter
salexigens DSM 3043 RepID=Q1R0K0_CHRSD
Length = 282
Score = 65.5 bits (158), Expect = 2e-09
Identities = 33/82 (40%), Positives = 48/82 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +P I LEA D+ E+++A+G E+ R+C++LL G
Sbjct: 198 GIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAFGSEVVTRLCQRLL-DGG 256
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
PG+H YTLN A+ +L+ L
Sbjct: 257 APGLHFYTLNQATPALRVLDNL 278
[200][TOP]
>UniRef100_C8XCS7 5,10-methylenetetrahydrofolate reductase n=1 Tax=Nakamurella
multipartita DSM 44233 RepID=C8XCS7_9ACTO
Length = 295
Score = 65.5 bits (158), Expect = 2e-09
Identities = 32/89 (35%), Positives = 53/89 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMP+ ++G R+ +VP +++D L A++++ EA +A G+E VRM + LL +G
Sbjct: 207 GIMPVTSHGRLMRIVELSGQRVPEQLADELYAVREDPEAGRAIGMEHAVRMSQDLLDAG- 265
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR 268
P +H YT N K+ + +L LG+ R
Sbjct: 266 APCLHFYTFNRSKATIEVLSALGMTPAMR 294
[201][TOP]
>UniRef100_C1ZF18 Methylenetetrahydrofolate reductase n=1 Tax=Planctomyces
limnophilus DSM 3776 RepID=C1ZF18_PLALI
Length = 310
Score = 65.5 bits (158), Expect = 2e-09
Identities = 37/86 (43%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEA--IKDNDEAVKAYGIELGVRMCRQLLAS 175
G+MPI Y KR+ TKVPAE+ + LEA ++D+ A GIE V+ C+ L+
Sbjct: 218 GVMPITEYSRVKRIVEISGTKVPAELLEQLEAAHLRDDKAAQLEIGIEYSVQQCQDLIDH 277
Query: 176 GEVPGVHMYTLNLEKSAVAILEQLGL 253
G VPG+H Y LN + IL+ LGL
Sbjct: 278 G-VPGLHFYVLNKAHATSQILQSLGL 302
[202][TOP]
>UniRef100_UPI00016A554F 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
ubonensis Bu RepID=UPI00016A554F
Length = 276
Score = 65.1 bits (157), Expect = 3e-09
Identities = 32/84 (38%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP I+ LE+ D+ +A++A+G ++ +C++LL +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADVVTGLCQRLLDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + I E+LG+
Sbjct: 253 VPGLHFYTLNSAAATKTICERLGV 276
[203][TOP]
>UniRef100_Q8Y389 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=Q8Y389_RALSO
Length = 276
Score = 65.1 bits (157), Expect = 3e-09
Identities = 32/84 (38%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C ++P I+ LE+ D+ E+++A+G+++ +C +LLA G
Sbjct: 194 GIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + AI ++LGL
Sbjct: 253 APGLHFYTLNAAAATRAIWQRLGL 276
[204][TOP]
>UniRef100_Q60CG9 Methylenetetrahydrofolate reductase n=1 Tax=Methylococcus
capsulatus RepID=Q60CG9_METCA
Length = 289
Score = 65.1 bits (157), Expect = 3e-09
Identities = 31/84 (36%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +P I LEA D+ +A++ +G+E+ +CR+LL G
Sbjct: 204 GIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDRKAIRTFGLEVVTELCRRLLEQG- 262
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN ++ + + + LGL
Sbjct: 263 APGLHFYTLNRAEACLEVWKALGL 286
[205][TOP]
>UniRef100_C6BI03 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12D
RepID=C6BI03_RALP1
Length = 276
Score = 65.1 bits (157), Expect = 3e-09
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C +VP I+ LE D+ E+++A+G+++ MC +LL G
Sbjct: 194 GIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN S AI ++LGL
Sbjct: 253 APGLHFYTLNAAGSTRAIWQRLGL 276
[206][TOP]
>UniRef100_B2U776 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia pickettii 12J
RepID=B2U776_RALPJ
Length = 276
Score = 65.1 bits (157), Expect = 3e-09
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C +VP I+ LE D+ E+++A+G+++ MC +LL G
Sbjct: 194 GIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN S AI ++LGL
Sbjct: 253 APGLHFYTLNAAGSTRAIWQRLGL 276
[207][TOP]
>UniRef100_A9KD99 Methylenetetrahydrofolate reductase n=1 Tax=Coxiella burnetii
Dugway 5J108-111 RepID=A9KD99_COXBN
Length = 290
Score = 65.1 bits (157), Expect = 3e-09
Identities = 33/91 (36%), Positives = 54/91 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + + + C T++P + LE+ K++ ++KAYG+E+ ++C L+A G
Sbjct: 197 GIMPISDFDKLVQFSKTCATEIPRWLYKRLESYKNDKASLKAYGVEVVTKLCEDLIAYG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ 274
VPG+H YTLN + I+E L + + R Q
Sbjct: 256 VPGLHFYTLNQCEPTQTIIENLQSITSFREQ 286
[208][TOP]
>UniRef100_B5S7H8 Methylenetetrahydrofolate reductase n=1 Tax=Ralstonia solanacearum
RepID=B5S7H8_RALSO
Length = 276
Score = 65.1 bits (157), Expect = 3e-09
Identities = 32/84 (38%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C ++P I+ LE+ D+ E+++A+G+++ +C +LLA G
Sbjct: 194 GIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + AI ++LGL
Sbjct: 253 APGLHFYTLNAAAATRAIWQRLGL 276
[209][TOP]
>UniRef100_UPI00016A8C43 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei DM98 RepID=UPI00016A8C43
Length = 276
Score = 64.7 bits (156), Expect = 4e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + + E+LGL
Sbjct: 253 VPGLHFYTLNGAAATKTVCERLGL 276
[210][TOP]
>UniRef100_Q3BXE0 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas campestris
pv. vesicatoria str. 85-10 RepID=Q3BXE0_XANC5
Length = 275
Score = 64.7 bits (156), Expect = 4e-09
Identities = 30/83 (36%), Positives = 50/83 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G E+ +C++L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAALCQRLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
P +H YTLNL K +L+ LG
Sbjct: 252 APALHFYTLNLAKPTTQVLQLLG 274
[211][TOP]
>UniRef100_A6GU55 Methylenetetrahydrofolate reductase n=1 Tax=Limnobacter sp. MED105
RepID=A6GU55_9BURK
Length = 286
Score = 64.7 bits (156), Expect = 4e-09
Identities = 28/83 (33%), Positives = 51/83 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMP+ + R + C ++P + + L+ D+ E+++A+G+E+ +C QL+ G
Sbjct: 204 GIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDRESIRAFGLEVVSNLCEQLIREG- 262
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YT+N + +AIL+Q+G
Sbjct: 263 APGLHFYTMNNAQPTLAILDQIG 285
[212][TOP]
>UniRef100_C4KXI8 Methylenetetrahydrofolate reductase n=23 Tax=pseudomallei group
RepID=C4KXI8_BURPS
Length = 276
Score = 64.7 bits (156), Expect = 4e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + + E+LGL
Sbjct: 253 VPGLHFYTLNGAAATKTVCERLGL 276
[213][TOP]
>UniRef100_A3RPV8 Methylenetetrahydrofolate reductase n=2 Tax=Ralstonia solanacearum
RepID=A3RPV8_RALSO
Length = 276
Score = 64.7 bits (156), Expect = 4e-09
Identities = 32/84 (38%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C ++P I+ LE+ D+ E+++A+G+++ +C +LLA G
Sbjct: 194 GIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDVVTALCDRLLAGG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + AI ++LGL
Sbjct: 253 APGLHFYTLNAAGATRAIWQRLGL 276
[214][TOP]
>UniRef100_A7QB31 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7QB31_VITVI
Length = 93
Score = 64.7 bits (156), Expect = 4e-09
Identities = 33/57 (57%), Positives = 39/57 (68%)
Frame = +2
Query: 8 MPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASG 178
MPI GF MTGFCKTKV A ALE IKDN++AV YGI LG MC+++L +G
Sbjct: 1 MPINNSKGFLGMTGFCKTKVTA----ALEPIKDNEKAVNTYGIHLGTEMCKKVLGNG 53
[215][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 64.7 bits (156), Expect = 4e-09
Identities = 32/87 (36%), Positives = 49/87 (56%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI TY F R + +P IS LEA ND+A+K+ G+E+ + + +
Sbjct: 217 GLMPITTYKVFTRASKLSHASIPKTISRKLEASVGNDDAIKSLGVEIVSDIINTITSKTS 276
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDT 262
+ G H YTLNLEK+ +IL+ ++ T
Sbjct: 277 IKGFHFYTLNLEKAVASILKNSTVMQT 303
[216][TOP]
>UniRef100_UPI00016AF3CB 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
thailandensis MSMB43 RepID=UPI00016AF3CB
Length = 276
Score = 64.3 bits (155), Expect = 5e-09
Identities = 31/84 (36%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP I+ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADVVTGLCRRLVDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + + E+LGL
Sbjct: 253 VPGLHFYTLNGAAATKIVCERLGL 276
[217][TOP]
>UniRef100_UPI00016A5F77 5,10-methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
oklahomensis EO147 RepID=UPI00016A5F77
Length = 276
Score = 64.3 bits (155), Expect = 5e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + + E+LGL
Sbjct: 253 VPGLHFYTLNGAAATKIVCERLGL 276
[218][TOP]
>UniRef100_Q8PP97 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas axonopodis
pv. citri RepID=Q8PP97_XANAC
Length = 275
Score = 64.3 bits (155), Expect = 5e-09
Identities = 30/83 (36%), Positives = 49/83 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G E+ +C +L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVVAALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
P +H YTLNL K +L+ LG
Sbjct: 252 APALHFYTLNLAKPTTQVLQLLG 274
[219][TOP]
>UniRef100_C1DIB8 Methylenetetrahydrofolate reductase n=1 Tax=Azotobacter vinelandii
DJ RepID=C1DIB8_AZOVD
Length = 281
Score = 64.3 bits (155), Expect = 5e-09
Identities = 33/84 (39%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P + LEA D+ E+++A+G ++ MC +LL G
Sbjct: 197 GIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFGEQVVTAMCEKLLEGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++AI LGL
Sbjct: 256 APGLHFYTLNQAEPSLAIWNNLGL 279
[220][TOP]
>UniRef100_B2I856 Methylenetetrahydrofolate reductase n=2 Tax=Xylella fastidiosa
RepID=B2I856_XYLF2
Length = 275
Score = 64.3 bits (155), Expect = 5e-09
Identities = 27/83 (32%), Positives = 52/83 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI + + + C ++P I+ ++A D+ ++++A+G ++ +C +L+A G
Sbjct: 193 GVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVVTALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLNL K + +L++LG
Sbjct: 252 APGLHFYTLNLAKPSTQVLQRLG 274
[221][TOP]
>UniRef100_A0K3F1 Methylenetetrahydrofolate reductase n=2 Tax=Burkholderia
cenocepacia RepID=A0K3F1_BURCH
Length = 276
Score = 64.3 bits (155), Expect = 5e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G ++ +C++L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTNLCQRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLNL + I E+L +
Sbjct: 253 VPGLHFYTLNLATATRTICERLAV 276
[222][TOP]
>UniRef100_Q3RB96 Methylenetetrahydrofolate reductase n=1 Tax=Xylella fastidiosa
subsp. sandyi Ann-1 RepID=Q3RB96_XYLFA
Length = 275
Score = 64.3 bits (155), Expect = 5e-09
Identities = 27/83 (32%), Positives = 52/83 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI + + + C ++P I+ ++A D+ ++++A+G ++ +C +L+A G
Sbjct: 193 GVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVVTALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLNL K + +L++LG
Sbjct: 252 APGLHFYTLNLAKPSTQVLQRLG 274
[223][TOP]
>UniRef100_B0U580 Methylenetetrahydrofolate reductase n=3 Tax=Xylella fastidiosa
RepID=B0U580_XYLFM
Length = 275
Score = 64.3 bits (155), Expect = 5e-09
Identities = 27/83 (32%), Positives = 52/83 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI + + + C ++P I+ ++A D+ ++++A+G ++ +C +L+A G
Sbjct: 193 GVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVVTALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLNL K + +L++LG
Sbjct: 252 APGLHFYTLNLAKPSTQVLQRLG 274
[224][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 64.3 bits (155), Expect = 5e-09
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLL---- 169
G+MPI +Y KR T K+P + D LEA++ +DE VK G+++ + Q+
Sbjct: 248 GLMPIQSYQMIKRTTKLSHAKIPDALMDRLEAVRGDDERVKEVGVDIVSELVEQIKEIKG 307
Query: 170 ASGEVP-GVHMYTLNLEKSAVAILEQLGLV 256
+ E P G H YTLNLEK+ I+E+ GL+
Sbjct: 308 RTAEGPKGFHFYTLNLEKAVSFIVERTGLI 337
[225][TOP]
>UniRef100_UPI00019EA439 5,10-methylenetetrahydrofolate reductase n=1 Tax=Nakamurella
multipartita DSM 44233 RepID=UPI00019EA439
Length = 94
Score = 63.9 bits (154), Expect = 6e-09
Identities = 32/89 (35%), Positives = 52/89 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMP+ + G R+ +VP +++D L A++++ EA +A G+E VRM + LL +G
Sbjct: 6 GIMPVTSEGRLMRIVELSGQRVPEQLADELYAVREDPEAGRAIGMEHAVRMSQDLLDAG- 64
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSR 268
P +H YT N K+ + +L LG+ R
Sbjct: 65 APCLHFYTFNRSKATIEVLSALGMTPAMR 93
[226][TOP]
>UniRef100_Q13T38 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia xenovorans
LB400 RepID=Q13T38_BURXL
Length = 276
Score = 63.9 bits (154), Expect = 6e-09
Identities = 31/84 (36%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP I+ LE+ D+ E+++A+G+++ +CR+L+ +
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDVVTDLCRRLI-DAK 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLN + AI E+L +
Sbjct: 253 VPGLHFYTLNGAAATKAICERLNV 276
[227][TOP]
>UniRef100_B1JTJ6 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
cenocepacia MC0-3 RepID=B1JTJ6_BURCC
Length = 276
Score = 63.9 bits (154), Expect = 6e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G ++ +C++L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTSLCQRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
VPG+H YTLNL + I E+L +
Sbjct: 253 VPGLHFYTLNLATATRTICERLAV 276
[228][TOP]
>UniRef100_A4XPF2 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas mendocina
ymp RepID=A4XPF2_PSEMY
Length = 281
Score = 63.9 bits (154), Expect = 6e-09
Identities = 31/84 (36%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P + LEA D+ ++++A+G ++ MC +LL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFGEQVITEMCERLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H Y++NL ++AI LGL
Sbjct: 256 APGLHFYSMNLAGPSLAIWNNLGL 279
[229][TOP]
>UniRef100_A2W5Y4 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia dolosa
AUO158 RepID=A2W5Y4_9BURK
Length = 276
Score = 63.9 bits (154), Expect = 6e-09
Identities = 31/82 (37%), Positives = 50/82 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G ++ +CR+LL +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTSLCRRLLDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
VPG+H YTLN + I E+L
Sbjct: 253 VPGLHFYTLNAAAATRTICERL 274
[230][TOP]
>UniRef100_Q5SLG6 Methylenetetrahydrofolate reductase n=2 Tax=Thermus thermophilus
RepID=Q5SLG6_THET8
Length = 296
Score = 63.5 bits (153), Expect = 8e-09
Identities = 34/84 (40%), Positives = 48/84 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMP+ +Y +R T C +P + LE +D+ +AV G+E VR +LL +G
Sbjct: 207 GIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQDDPKAVLEIGVEHAVRQVAELLEAG- 265
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
V GVH YTLN + +LE+LGL
Sbjct: 266 VEGVHFYTLNKSPATRMVLERLGL 289
[231][TOP]
>UniRef100_Q2NZD1 Methylenetetrahydrofolate reductase n=2 Tax=Xanthomonas oryzae pv.
oryzae RepID=Q2NZD1_XANOM
Length = 275
Score = 63.5 bits (153), Expect = 8e-09
Identities = 29/83 (34%), Positives = 49/83 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G ++ +C +L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVVAALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
P +H YTLNL K +L+ LG
Sbjct: 252 APALHFYTLNLAKPTTQVLQLLG 274
[232][TOP]
>UniRef100_Q21NJ7 Methylenetetrahydrofolate reductase n=1 Tax=Saccharophagus
degradans 2-40 RepID=Q21NJ7_SACD2
Length = 297
Score = 63.5 bits (153), Expect = 8e-09
Identities = 32/91 (35%), Positives = 49/91 (53%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI+ Y R + C +P + +E+ DN EA+ ++GI+ +C LL +G
Sbjct: 197 GIMPILNYRNLARFSDSCGADIPRWMRKRMESFGDNQEALISFGIDWISELCDTLLDAG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVDTSRVQ 274
PG+H YT+N + I++ LGL D Q
Sbjct: 256 APGLHFYTMNQTEPTATIIKNLGLEDAPDAQ 286
[233][TOP]
>UniRef100_B2SPM2 Methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae pv.
oryzae PXO99A RepID=B2SPM2_XANOP
Length = 275
Score = 63.5 bits (153), Expect = 8e-09
Identities = 29/83 (34%), Positives = 49/83 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G ++ +C +L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVVAALCERLMAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
P +H YTLNL K +L+ LG
Sbjct: 252 APALHFYTLNLAKPTTQVLQLLG 274
[234][TOP]
>UniRef100_C4KD22 Methylenetetrahydrofolate reductase n=1 Tax=Thauera sp. MZ1T
RepID=C4KD22_THASP
Length = 277
Score = 63.5 bits (153), Expect = 8e-09
Identities = 28/84 (33%), Positives = 51/84 (60%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI ++ R + C ++P + E+ D+ +A++A+G+++ R+C +LLA+G
Sbjct: 193 GIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVVTRLCEKLLAAG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H Y++N+ I +LGL
Sbjct: 252 APGLHFYSMNMAGPTTEICRRLGL 275
[235][TOP]
>UniRef100_A8UU31 Methylenetetrahydrofolate reductase n=1 Tax=Hydrogenivirga sp.
128-5-R1-1 RepID=A8UU31_9AQUI
Length = 298
Score = 63.5 bits (153), Expect = 8e-09
Identities = 29/78 (37%), Positives = 43/78 (55%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + K+ C +P + + +E ++D E V G+E V+ C LL +G
Sbjct: 207 GIMPITNFKQIKKFASMCGATIPQSLIEKMEPVEDKPEEVAKIGVEFAVKQCEDLLRNG- 265
Query: 182 VPGVHMYTLNLEKSAVAI 235
VPG+H YTLN K+ + I
Sbjct: 266 VPGLHFYTLNRSKATLNI 283
[236][TOP]
>UniRef100_UPI0001695145 5,10-methylenetetrahydrofolate reductase n=1 Tax=Xanthomonas oryzae
pv. oryzicola BLS256 RepID=UPI0001695145
Length = 275
Score = 63.2 bits (152), Expect = 1e-08
Identities = 29/83 (34%), Positives = 49/83 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + +R + C ++P I +++ D+ +AV+A+G ++ +C +L+A G
Sbjct: 193 GIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVVAALCERLMAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
P +H YTLNL K +L+ LG
Sbjct: 252 APALHFYTLNLAKPTTQVLQLLG 274
[237][TOP]
>UniRef100_Q9PEA7 Methylenetetrahydrofolate reductase n=1 Tax=Xylella fastidiosa
RepID=Q9PEA7_XYLFA
Length = 275
Score = 63.2 bits (152), Expect = 1e-08
Identities = 27/83 (32%), Positives = 51/83 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI + + C ++P I+ ++A D+ ++++A+G ++ +C +L+A G
Sbjct: 193 GVMPISNFDKLHHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVVTALCERLIAGG- 251
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLNL K + +L++LG
Sbjct: 252 APGLHFYTLNLAKPSTQVLQRLG 274
[238][TOP]
>UniRef100_A0LTK4 Methylenetetrahydrofolate reductase n=1 Tax=Acidothermus
cellulolyticus 11B RepID=A0LTK4_ACIC1
Length = 331
Score = 63.2 bits (152), Expect = 1e-08
Identities = 33/84 (39%), Positives = 47/84 (55%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
G+MPI + G +R + P E++D + A+ D AV+A GIE+ MCR+LL G
Sbjct: 219 GVMPITSIGQIERFALLSGDEFPPELADRILAVADQPAAVRAIGIEVATEMCRRLLDEG- 277
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + I + L L
Sbjct: 278 APGLHFYTLNRSTATREIYQNLRL 301
[239][TOP]
>UniRef100_C7HXI3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Thiomonas
intermedia K12 RepID=C7HXI3_THIIN
Length = 285
Score = 63.2 bits (152), Expect = 1e-08
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI R + C ++P I L++ D+ E+++A+G E+ +C +L+ASG
Sbjct: 203 GIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRESIRAFGREVVSSLCEELIASG- 261
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLN ++ +A+L+ LG
Sbjct: 262 APGLHFYTLNQAEATLAVLDDLG 284
[240][TOP]
>UniRef100_A9AD52 Methylenetetrahydrofolate reductase n=4 Tax=Burkholderia
multivorans RepID=A9AD52_BURM1
Length = 276
Score = 63.2 bits (152), Expect = 1e-08
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G ++ +C++L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADVVTGLCQRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
VPG+H YTLN + AI E+L
Sbjct: 253 VPGLHFYTLNAAAATKAICERL 274
[241][TOP]
>UniRef100_A4LN89 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia
pseudomallei 305 RepID=A4LN89_BURPS
Length = 276
Score = 63.2 bits (152), Expect = 1e-08
Identities = 29/83 (34%), Positives = 51/83 (61%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ ++++A+G ++ +CR+L+ +G
Sbjct: 194 GIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADVVTGLCRRLIDAG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
VPG+H YTLN + + E+LG
Sbjct: 253 VPGLHFYTLNGAAATKTVCERLG 275
[242][TOP]
>UniRef100_A0Y9Q7 Methylenetetrahydrofolate reductase n=1 Tax=marine gamma
proteobacterium HTCC2143 RepID=A0Y9Q7_9GAMM
Length = 276
Score = 63.2 bits (152), Expect = 1e-08
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LE+ ++ E+V+ +GIE+ ++C++LLA G
Sbjct: 194 GIMPITNYHNLARFSKSCGAEIPRWICQRLESFGNDSESVQEFGIEVVTQLCQRLLAEG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N + I + LG+
Sbjct: 253 APGIHFYTMNQVEPNRQIWKNLGI 276
[243][TOP]
>UniRef100_UPI0001AF5FB3 5,10-methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas
syringae pv. oryzae str. 1_6 RepID=UPI0001AF5FB3
Length = 281
Score = 62.8 bits (151), Expect = 1e-08
Identities = 32/84 (38%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ ++++A+G E+ +MC +LL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++A+ L L
Sbjct: 256 APGLHFYTLNQAEPSLAVWNNLQL 279
[244][TOP]
>UniRef100_Q4ZZ93 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. syringae B728a RepID=Q4ZZ93_PSEU2
Length = 281
Score = 62.8 bits (151), Expect = 1e-08
Identities = 32/84 (38%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ ++++A+G E+ +MC +LL G
Sbjct: 197 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGG- 255
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++A+ L L
Sbjct: 256 APGLHFYTLNQAEPSLAVWNNLQL 279
[245][TOP]
>UniRef100_Q48PB6 Methylenetetrahydrofolate reductase n=1 Tax=Pseudomonas syringae
pv. phaseolicola 1448A RepID=Q48PB6_PSE14
Length = 291
Score = 62.8 bits (151), Expect = 1e-08
Identities = 32/84 (38%), Positives = 49/84 (58%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I LEA D+ ++++A+G E+ +MC +LL G
Sbjct: 207 GIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGG- 265
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YTLN + ++A+ L L
Sbjct: 266 TPGLHFYTLNQAEPSLAVWNNLQL 289
[246][TOP]
>UniRef100_Q1D7X5 Methylenetetrahydrofolate reductase n=1 Tax=Myxococcus xanthus DK
1622 RepID=Q1D7X5_MYXXD
Length = 290
Score = 62.8 bits (151), Expect = 1e-08
Identities = 33/82 (40%), Positives = 44/82 (53%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y +R T C VP ++ LE +KDN EA+ G+ C +LL+ G
Sbjct: 206 GIMPITNYEQIQRFTRLCGATVPMRLALQLERVKDNPEAMAQLGVAHATVQCMELLSRG- 264
Query: 182 VPGVHMYTLNLEKSAVAILEQL 247
VPG+H YTLN + I+ L
Sbjct: 265 VPGIHFYTLNKSPATRMIVSAL 286
[247][TOP]
>UniRef100_C5BTQ6 Methylenetetrahydrofolate reductase n=1 Tax=Teredinibacter turnerae
T7901 RepID=C5BTQ6_TERTT
Length = 282
Score = 62.8 bits (151), Expect = 1e-08
Identities = 33/86 (38%), Positives = 46/86 (53%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C ++P I L DN E+++A+ +L +C LL +G
Sbjct: 198 GIMPITNYQNIARFSDACGAEIPRWIRKRLNDFGDNQESLQAFTTDLVTELCATLLENG- 256
Query: 182 VPGVHMYTLNLEKSAVAILEQLGLVD 259
PG+H YT+N + IL LGLVD
Sbjct: 257 APGLHFYTMNQVEPTRTILTNLGLVD 282
[248][TOP]
>UniRef100_B8GP49 Methylenetetrahydrofolate reductase n=1 Tax=Thioalkalivibrio sp.
HL-EbGR7 RepID=B8GP49_THISH
Length = 286
Score = 62.8 bits (151), Expect = 1e-08
Identities = 32/84 (38%), Positives = 46/84 (54%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI Y R + C +P I LE D+ A++A+G ++ R+C +LL +G
Sbjct: 201 GIMPITNYTQLARFSDACGADIPRWIRKRLEGFGDDSAAIRAFGEDVVTRLCEKLLEAG- 259
Query: 182 VPGVHMYTLNLEKSAVAILEQLGL 253
PG+H YT+N +AI LGL
Sbjct: 260 APGLHFYTMNQAGPTLAIWNNLGL 283
[249][TOP]
>UniRef100_C5A8X3 Methylenetetrahydrofolate reductase n=1 Tax=Burkholderia glumae
BGR1 RepID=C5A8X3_BURGB
Length = 276
Score = 62.8 bits (151), Expect = 1e-08
Identities = 29/83 (34%), Positives = 48/83 (57%)
Frame = +2
Query: 2 GIMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGE 181
GIMPI + R + C +VP ++ LE+ D+ E+++A+G ++ MC +L+ G
Sbjct: 194 GIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDKESIRAFGADVVTAMCERLIREG- 252
Query: 182 VPGVHMYTLNLEKSAVAILEQLG 250
PG+H YTLN + + E+LG
Sbjct: 253 APGLHFYTLNAATATKVVCERLG 275
[250][TOP]
>UniRef100_B5HCL5 Methylenetetrahydrofolate reductase n=1 Tax=Streptomyces
pristinaespiralis ATCC 25486 RepID=B5HCL5_STRPR
Length = 305
Score = 62.8 bits (151), Expect = 1e-08
Identities = 33/87 (37%), Positives = 48/87 (55%)
Frame = +2
Query: 5 IMPIMTYGGFKRMTGFCKTKVPAEISDALEAIKDNDEAVKAYGIELGVRMCRQLLASGEV 184
IMP+ + +R PAE+ + + A+KD+ AV++ GIE C +LLA G V
Sbjct: 220 IMPVTSVKQIERFATLSNAHFPAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEG-V 278
Query: 185 PGVHMYTLNLEKSAVAILEQLGLVDTS 265
PG+H TLN + + I E LGL + S
Sbjct: 279 PGLHFITLNNSTATLEIYENLGLHEQS 305