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[1][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 303 bits (777), Expect = 5e-81
Identities = 145/145 (100%), Positives = 145/145 (100%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ
Sbjct: 450 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK
Sbjct: 510 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 569
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
NSYYLVSLVENDYINGDIFAVFADL
Sbjct: 570 NSYYLVSLVENDYINGDIFAVFADL 594
[2][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 263 bits (673), Expect = 6e-69
Identities = 122/143 (85%), Positives = 131/143 (91%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E WVSNT +
Sbjct: 260 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 319
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYPE DPSR LLEEVK
Sbjct: 320 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 379
Query: 237 NSYYLVSLVENDYINGDIFAVFA 169
NSYYLVSLV+N+YINGDIF+VFA
Sbjct: 380 NSYYLVSLVDNNYINGDIFSVFA 402
[3][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 263 bits (673), Expect = 6e-69
Identities = 122/143 (85%), Positives = 131/143 (91%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP +GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E WVSNT +
Sbjct: 450 SDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+DVNAVTWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYPE DPSR LLEEVK
Sbjct: 510 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 569
Query: 237 NSYYLVSLVENDYINGDIFAVFA 169
NSYYLVSLV+N+YINGDIF+VFA
Sbjct: 570 NSYYLVSLVDNNYINGDIFSVFA 592
[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 257 bits (657), Expect = 4e-67
Identities = 117/145 (80%), Positives = 132/145 (91%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAYLEFFCSKEKL+A+VE+CKA P +TYMAVN+G W+SN A
Sbjct: 464 SDSPSVGWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVAL 523
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
DVNAVTWGVFPAKEIIQPT+VDP SF+VWKDEAFE WSR WA+LYPE DPSR LLEEV+
Sbjct: 524 TDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQ 583
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
NSY+LVSLV+NDYI+GDIFAVFA+L
Sbjct: 584 NSYFLVSLVDNDYIHGDIFAVFAEL 608
[5][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 253 bits (645), Expect = 1e-65
Identities = 114/145 (78%), Positives = 131/145 (90%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAYLEFFCSK+KL+A+V+KCK+ P +TY+AVNKG W+SN A
Sbjct: 80 SDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVAL 139
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
DVNAVTWGVFP KEIIQPT+VDP SF+VWKDEAFE WSR WA+LYPE DPSR LLEEV+
Sbjct: 140 TDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQ 199
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
+SY+LVSLV+NDYI+GDIFAVFADL
Sbjct: 200 SSYFLVSLVDNDYIHGDIFAVFADL 224
[6][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 249 bits (637), Expect = 9e-65
Identities = 113/145 (77%), Positives = 130/145 (89%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAYLEFFCSK+KL+A+V+KCK+ P +TY+AVNKG W+SN A
Sbjct: 461 SDSPSVGWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVAL 520
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
DVNAVTWGVFP KEIIQPT+VDP SF+VWKDEAFE WSR WA+LYPE DPSR LLEEV+
Sbjct: 521 TDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQ 580
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
+SY+LVSLV+NDYI+GDIFAVFA L
Sbjct: 581 SSYFLVSLVDNDYIHGDIFAVFAAL 605
[7][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 246 bits (628), Expect = 1e-63
Identities = 112/145 (77%), Positives = 130/145 (89%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAY+EFFCS +KL A++EKCKALP +TYMAVN+G +SN Q
Sbjct: 465 SDSPSVGWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQ 524
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
DVNAVTWGVFP K+IIQPT+VDPASF+VWKDEAFE W+R WA+LYPE+DPSR LLEEV+
Sbjct: 525 NDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPSRKLLEEVQ 584
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
+SY+LVSLV+NDYI GDIFAVFADL
Sbjct: 585 SSYFLVSLVDNDYIQGDIFAVFADL 609
[8][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 237 bits (604), Expect = 6e-61
Identities = 108/144 (75%), Positives = 126/144 (87%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK PS+TYMAVNK W+SN
Sbjct: 450 SDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYPE DPSR LLEEV+
Sbjct: 510 GEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVFAD 166
NS++LVSLV+NDYINGD+FA+F +
Sbjct: 570 NSHFLVSLVDNDYINGDLFAIFME 593
[9][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 234 bits (596), Expect = 5e-60
Identities = 107/144 (74%), Positives = 125/144 (86%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK S+TYMAVNK W+SN
Sbjct: 450 SDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYPE DPSR LLEEV+
Sbjct: 510 GEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVFAD 166
NS++LVSLV+NDYINGD+FA+F +
Sbjct: 570 NSHFLVSLVDNDYINGDLFAIFME 593
[10][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 234 bits (596), Expect = 5e-60
Identities = 107/144 (74%), Positives = 125/144 (86%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCS+EKL+A+V+KCK S+TYMAVNK W+SN
Sbjct: 443 SDSLSVGWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGP 502
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+VNAVTWGVFPA+EIIQPT+VDP+SF VWKDEAFE WSR WA LYPE DPSR LLEEV+
Sbjct: 503 GEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPSRKLLEEVQ 562
Query: 237 NSYYLVSLVENDYINGDIFAVFAD 166
NS++LVSLV+NDYINGD+FA+F +
Sbjct: 563 NSHFLVSLVDNDYINGDLFAIFME 586
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 226 bits (575), Expect = 1e-57
Identities = 105/142 (73%), Positives = 119/142 (83%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSPTVGWGGP GYVYQKAYLEFFC+KEKLD ++EK KA PS+TY+AVNK + SN A
Sbjct: 450 SDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KEIIQPT+VDPASF VWKDEAFE W+R WA L+PE D SR LLE+V+
Sbjct: 510 NAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEGDSSRELLEKVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVF 172
SYYLVSLV+NDY+ GD+FA F
Sbjct: 570 KSYYLVSLVDNDYVQGDLFAAF 591
[12][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 223 bits (568), Expect = 9e-57
Identities = 99/145 (68%), Positives = 121/145 (83%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP++GWGG GYVYQKAY+EFFCS EKL+ +VEK K LP +TY+AVNK +N
Sbjct: 450 SDSPSIGWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
DVNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+ W + WA+LYP+ DPSR +LEEV+
Sbjct: 510 TDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYPDGDPSRKILEEVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
NSYYLVS+V+NDYI+GD+F+VF +L
Sbjct: 570 NSYYLVSVVDNDYIHGDLFSVFEEL 594
[13][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 220 bits (561), Expect = 6e-56
Identities = 99/143 (69%), Positives = 118/143 (82%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAY+EFFCS EKL AV+EK K PS+TY+AVN + SN
Sbjct: 450 SDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+ W + WA+LYPE D SR +L E+K
Sbjct: 510 TSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYPEDDASRKILSEIK 569
Query: 237 NSYYLVSLVENDYINGDIFAVFA 169
+SY+LVS+V+NDYINGD+F+VFA
Sbjct: 570 SSYFLVSMVDNDYINGDLFSVFA 592
[14][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 218 bits (555), Expect = 3e-55
Identities = 100/145 (68%), Positives = 120/145 (82%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S+SP+VGWGGP GYVYQKAY+EFFC+KEKL ++EK KA PS+TY+AVNK + +SN
Sbjct: 438 SESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPA 497
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KEIIQPT+VD ASF VWKDEAFE WSR WA L+PE D SR LLE+++
Sbjct: 498 NAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQIQ 557
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
SYYLVSLV+NDYI+GD+FA F ++
Sbjct: 558 KSYYLVSLVDNDYISGDLFAAFKEI 582
[15][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 218 bits (555), Expect = 3e-55
Identities = 100/142 (70%), Positives = 117/142 (82%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSPTVGWGGP GYVYQKAYLEFFC+KEKLD ++EK KA PS+TY+AVNK + SN +
Sbjct: 450 SDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KEIIQPT+VD ASF VWKDEAFE W+R W ++PE D SR LLE+V+
Sbjct: 510 NAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSSRELLEKVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVF 172
+YYLVSLV+NDY+ GD+FA F
Sbjct: 570 KTYYLVSLVDNDYVQGDLFAAF 591
[16][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 217 bits (553), Expect = 5e-55
Identities = 100/145 (68%), Positives = 119/145 (82%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+AVNK + SN
Sbjct: 93 SDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPT 152
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+PE D SR +L++V+
Sbjct: 153 NAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQ 212
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
SY+LVSLV+NDYINGD+FA F ++
Sbjct: 213 KSYFLVSLVDNDYINGDLFAAFKEI 237
[17][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 217 bits (553), Expect = 5e-55
Identities = 100/145 (68%), Positives = 119/145 (82%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+AVNK + SN
Sbjct: 450 SDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPT 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+PE D SR +L++V+
Sbjct: 510 NAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKVQ 569
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
SY+LVSLV+NDYINGD+FA F ++
Sbjct: 570 KSYFLVSLVDNDYINGDLFAAFKEI 594
[18][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 216 bits (551), Expect = 8e-55
Identities = 100/145 (68%), Positives = 118/145 (81%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDSP+VGWGGP GYVYQKAY+EFFCS EKL AV+EK K+ PS+T++AVN + SN
Sbjct: 450 SDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGP 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFPAKE+IQPT+VDP SF VWKDEAF+TW WA LY E D SR +L E+K
Sbjct: 510 NCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYSEEDSSRKILSEIK 569
Query: 237 NSYYLVSLVENDYINGDIFAVFADL 163
+SY+LVS+V+NDYINGD+FAVFA L
Sbjct: 570 DSYFLVSMVDNDYINGDLFAVFATL 594
[19][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 179 bits (454), Expect = 1e-43
Identities = 83/119 (69%), Positives = 96/119 (80%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SDS +VGWGGP GYVYQKAYLEFFCSKEKLD ++EK KA PS+TY+AVNK + SN
Sbjct: 450 SDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPT 509
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
VNAVTWGVFP KEI+QPT+VD ASF VWKDEAFE WS+ WA L+PE D SR +L++V
Sbjct: 510 NAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSSREILDKV 568
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 162 bits (409), Expect = 2e-38
Identities = 78/141 (55%), Positives = 93/141 (65%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD GWGGP GYVY KAY+EFFCS E + K A PSITY+A N A
Sbjct: 451 SDDAVHGWGGPGGYVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAP 510
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VNAVTWGVFP KE+IQPT+V SF VWKDEAFE W+ W LY E +R+LL +K
Sbjct: 511 DAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYEEGSAARDLLAGIK 570
Query: 237 NSYYLVSLVENDYINGDIFAV 175
+S+ LVS+V+NDY+ GD+F V
Sbjct: 571 DSWVLVSVVDNDYVAGDLFGV 591
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 154 bits (388), Expect = 7e-36
Identities = 76/143 (53%), Positives = 96/143 (67%), Gaps = 1/143 (0%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVN-KGEQWVSNTAQADVNA 403
GWGG G VY+KAY+EFF S E ++E K P ITY AVN KG+ S T NA
Sbjct: 464 GWGGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGD---SKTNTKGTNA 520
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYL 223
VTWG+FP KEIIQPT+VD SF VWKDEAF W W++ Y + SR LL+ + N+YYL
Sbjct: 521 VTWGIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTYSPSSTSRTLLDSMINNYYL 580
Query: 222 VSLVENDYINGDIFAVFADL*EN 154
+++V+N++ING+IF F DL N
Sbjct: 581 INIVDNNFINGNIFQSFTDLVNN 603
[22][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 150 bits (379), Expect = 7e-35
Identities = 70/134 (52%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y VN Q ++N A
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQNITNAA 546
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY E PSR +++ +
Sbjct: 547 DLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLYEEESPSRMIIQYI 606
Query: 240 KNSYYLVSLVENDY 199
++YYLV+LV+ND+
Sbjct: 607 HDNYYLVNLVDNDF 620
[23][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 149 bits (375), Expect = 2e-34
Identities = 72/155 (46%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y VN Q ++N A
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQNITNAA 546
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+AVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY E PSR +++ +
Sbjct: 547 DLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQYI 606
Query: 240 KNSYYLVSLVENDY-INGDIFAVFADL*ENQETTT 139
++YYLV+LV+ND+ + ++ V D + ++ T
Sbjct: 607 HDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDSPT 641
[24][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 148 bits (373), Expect = 4e-34
Identities = 71/147 (48%), Positives = 95/147 (64%), Gaps = 2/147 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVN-KGEQWVSNTA 421
S P VGWG P GYV+QKAYLEFF S+E + A+ + P++ Y + +G+ +N
Sbjct: 482 STDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNCD 541
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
Q AVTWGVFP KEIIQPT+VDP SF WKDEAF W+ W LY E SR L++ +
Sbjct: 542 QQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKSRELIQHI 601
Query: 240 KNSYYLVSLVENDYINGDI-FAVFADL 163
+++YLV+LV+ND+ +I F V D+
Sbjct: 602 HDTWYLVNLVDNDFPRDNILFTVIEDM 628
[25][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 147 bits (372), Expect = 5e-34
Identities = 69/131 (52%), Positives = 88/131 (67%), Gaps = 1/131 (0%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQW-VSNTAQADVNA 403
GWGGP GYVYQKAYLEFF S E+ ++E P I Y A++ E VSN+ A
Sbjct: 483 GWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIA 542
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYL 223
VTWGVFP +EI+QPT+VDP SF+ WKDEAF W+ WANLYPE SR ++ ++ L
Sbjct: 543 VTWGVFPGREILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAAVRNFVL 602
Query: 222 VSLVENDYING 190
V++V+ND+I G
Sbjct: 603 VNMVDNDFIQG 613
[26][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 147 bits (371), Expect = 6e-34
Identities = 66/138 (47%), Positives = 92/138 (66%), Gaps = 1/138 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQW-VSNTA 421
S P +GWGG GY+YQKAYLEFF S E + ++++ K P + Y VN + ++N
Sbjct: 438 STDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVDITNCD 497
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
AVTWGVFP +EI+QPT+VDP SF +WKDEAF W + W+ LY E SR ++ ++
Sbjct: 498 SQTPVAVTWGVFPGREIVQPTVVDPISFKIWKDEAFSLWEQQWSRLYTEDSKSRAIINKI 557
Query: 240 KNSYYLVSLVENDYINGD 187
N+Y LV+LV+ND+I G+
Sbjct: 558 MNTYCLVNLVDNDFIKGN 575
[27][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 147 bits (371), Expect = 6e-34
Identities = 76/143 (53%), Positives = 92/143 (64%), Gaps = 1/143 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD GWG P GYVYQKAYLEFF S + L ++ + + P ITY AVNK +NT
Sbjct: 445 SDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTHS 504
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAFE WA+LYP PSR L+ +
Sbjct: 505 ESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYPAESPSRKLITDTM 563
Query: 237 NSYYLVSLVENDYING-DIFAVF 172
N+ YLV++V ND+ +G IF F
Sbjct: 564 NTSYLVNIVANDFRDGMSIFEPF 586
[28][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 147 bits (371), Expect = 6e-34
Identities = 78/143 (54%), Positives = 93/143 (65%), Gaps = 1/143 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD GWG GYVYQKAYLEFF S E LDA++ + +A P ITY AVN +NT
Sbjct: 457 SDDKVHGWGPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNS 516
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP EIIQPTIV+ SF WKDEA+E R+WA +Y PSR LE++
Sbjct: 517 EAPNAVTWGVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYEPTSPSRKFLEDMF 575
Query: 237 NSYYLVSLVENDY-INGDIFAVF 172
NSY+LV++V ND+ N IF F
Sbjct: 576 NSYFLVNVVHNDFKANDSIFEPF 598
[29][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 146 bits (368), Expect = 1e-33
Identities = 68/138 (49%), Positives = 90/138 (65%), Gaps = 1/138 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNK-GEQWVSNTA 421
S+ P GWG P GYV+QKAYLEFF +E + + K I + VN GE +N
Sbjct: 467 SEDPNHGWGKPGGYVFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNAN 526
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWGVFP EI+QPT+VDP +F+ WKDEAF W + W LYPE SR++++ +
Sbjct: 527 MYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRSRDIIDSI 586
Query: 240 KNSYYLVSLVENDYINGD 187
+SYYLV+LV+NDY+ G+
Sbjct: 587 YDSYYLVNLVDNDYVGGN 604
[30][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 144 bits (362), Expect = 7e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 516 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 575
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 576 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 635
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 636 HDNYFLVNLVDNDF 649
[31][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 144 bits (362), Expect = 7e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 534 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 593
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 653
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 654 HDNYFLVNLVDNDF 667
[32][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 144 bits (362), Expect = 7e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 493 SSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 552
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 553 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYI 612
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 613 HDNYFLVNLVDNDF 626
[33][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 143 bits (361), Expect = 9e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 516 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 575
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 576 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 635
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 636 HDNYFLVNLVDNDF 649
[34][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 143 bits (361), Expect = 9e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 534 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 593
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 653
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 654 HDNYFLVNLVDNDF 667
[35][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 143 bits (361), Expect = 9e-33
Identities = 65/134 (48%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 493 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 552
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 553 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYI 612
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 613 HDNYFLVNLVDNDF 626
[36][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 143 bits (360), Expect = 1e-32
Identities = 68/134 (50%), Positives = 88/134 (65%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S E + A+++ K + Y VN Q ++N
Sbjct: 495 STDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQNITNAP 554
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY E PSR +++ +
Sbjct: 555 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 614
Query: 240 KNSYYLVSLVENDY 199
++YYLV+LV+ND+
Sbjct: 615 HDNYYLVNLVDNDF 628
[37][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 142 bits (358), Expect = 2e-32
Identities = 67/147 (45%), Positives = 95/147 (64%), Gaps = 2/147 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVNKGEQWVSNTA 421
S VGWG GYV+QKAYLEFF S E + A+++ K P + Y VN + ++N
Sbjct: 493 SSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAH 552
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY + PSR +++ +
Sbjct: 553 DMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYI 612
Query: 240 KNSYYLVSLVENDY-INGDIFAVFADL 163
++Y+LV+LV+ND+ ++ ++ V D+
Sbjct: 613 HDNYFLVNLVDNDFPLDNCLWQVIEDM 639
[38][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 142 bits (357), Expect = 3e-32
Identities = 64/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 492 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 612 HDNYFLVNLVDNDF 625
[39][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 141 bits (355), Expect = 5e-32
Identities = 67/134 (50%), Positives = 87/134 (64%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P GWG GYV+QKAYLEFF S E + A+++ K + Y VN Q ++N
Sbjct: 352 STDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP 411
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY E PSR +++ +
Sbjct: 412 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 471
Query: 240 KNSYYLVSLVENDY 199
++YYLV+LV+ND+
Sbjct: 472 HDNYYLVNLVDNDF 485
[40][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 141 bits (355), Expect = 5e-32
Identities = 62/135 (45%), Positives = 91/135 (67%), Gaps = 1/135 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 498 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 557
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EI+QPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 558 ELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 617
Query: 240 KNSYYLVSLVENDYI 196
++Y+LV+LV+N+++
Sbjct: 618 HDNYFLVNLVDNEFL 632
[41][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 141 bits (355), Expect = 5e-32
Identities = 62/135 (45%), Positives = 91/135 (67%), Gaps = 1/135 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EI+QPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652
Query: 240 KNSYYLVSLVENDYI 196
++Y+LV+LV+N+++
Sbjct: 653 HDNYFLVNLVDNEFL 667
[42][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 141 bits (355), Expect = 5e-32
Identities = 67/134 (50%), Positives = 87/134 (64%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P GWG GYV+QKAYLEFF S E + A+++ K + Y VN Q ++N
Sbjct: 484 STDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP 543
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W WA LY E PSR +++ +
Sbjct: 544 DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI 603
Query: 240 KNSYYLVSLVENDY 199
++YYLV+LV+ND+
Sbjct: 604 HDNYYLVNLVDNDF 617
[43][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 140 bits (354), Expect = 6e-32
Identities = 64/134 (47%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S E ++A+++ K + Y VN + ++N
Sbjct: 487 STDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAP 546
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 547 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 606
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 607 HDNYHLVNLVDNEF 620
[44][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 140 bits (354), Expect = 6e-32
Identities = 65/134 (48%), Positives = 88/134 (65%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVNKGEQWVSNTA 421
S P VGWG GYVYQKAYLEFF S E + A+++ K P + Y VN + ++N
Sbjct: 497 STDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAP 556
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+F +EI+QPT+VDP SF WKDEAF W WA LY + PSR +++ +
Sbjct: 557 DMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+ND+
Sbjct: 617 HDNYFLVNLVDNDF 630
[45][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 140 bits (354), Expect = 6e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 4 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 63
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 64 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 123
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 124 HDNYFLVNLVDNEF 137
[46][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 140 bits (354), Expect = 6e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEESPSRMIIQYI 652
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 653 HDNYFLVNLVDNEF 666
[47][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 140 bits (354), Expect = 6e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 653 HDNYFLVNLVDNEF 666
[48][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 140 bits (354), Expect = 6e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 533 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 592
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 593 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 652
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 653 HDNYFLVNLVDNEF 666
[49][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 140 bits (354), Expect = 6e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 492 SSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAP 551
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 612 HDNYFLVNLVDNEF 625
[50][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 140 bits (353), Expect = 8e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 492 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 612 HDNYFLVNLVDNEF 625
[51][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 140 bits (353), Expect = 8e-32
Identities = 63/134 (47%), Positives = 90/134 (67%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E ++A+++ K + Y V+ + ++N
Sbjct: 492 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAP 551
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 552 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 611
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 612 HDNYFLVNLVDNEF 625
[52][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 139 bits (350), Expect = 2e-31
Identities = 63/134 (47%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E + A+++ K + Y V+ + ++N
Sbjct: 618 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAP 677
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 678 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 737
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 738 HDNYFLVNLVDNEF 751
[53][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 139 bits (350), Expect = 2e-31
Identities = 63/134 (47%), Positives = 89/134 (66%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E + A+++ K + Y V+ + ++N
Sbjct: 534 SSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAP 593
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 594 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI 653
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 654 HDNYFLVNLVDNEF 667
[54][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 138 bits (348), Expect = 3e-31
Identities = 65/132 (49%), Positives = 85/132 (64%), Gaps = 1/132 (0%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNK-GEQWVSNTAQADVNA 403
GWGG GY+YQKAYLEFF K+ +D ++E P + Y ++ G +N + A
Sbjct: 477 GWGGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIA 536
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYL 223
VTWGVFP KEIIQPT+VDP SFN WKDEAF W W +LY S +++ + N +YL
Sbjct: 537 VTWGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFYL 596
Query: 222 VSLVENDYINGD 187
V+LV+NDYI G+
Sbjct: 597 VNLVDNDYIKGN 608
[55][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 138 bits (347), Expect = 4e-31
Identities = 70/133 (52%), Positives = 86/133 (64%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD P GWG GYVYQKAYLEFF S ++LD ++ + A P ITY AVN +NT
Sbjct: 366 SDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTS 425
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWG FP EI+QPTIV+ SF WKDEA+E R WA Y P+R LLE V
Sbjct: 426 DAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEPESPTRRLLEHVF 484
Query: 237 NSYYLVSLVENDY 199
++Y+LV++V ND+
Sbjct: 485 DTYFLVNVVHNDF 497
[56][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 137 bits (346), Expect = 5e-31
Identities = 64/134 (47%), Positives = 87/134 (64%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S E + A+++ K + Y VN + ++N
Sbjct: 490 SADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNVKGENITNAP 549
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+FP +EIIQPT+VDP SF WKDEAF W W LY E PSR +++ +
Sbjct: 550 DMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLYEEESPSRMIIQYI 609
Query: 240 KNSYYLVSLVENDY 199
++Y+LV+LV+N++
Sbjct: 610 HDNYHLVNLVDNEF 623
[57][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 137 bits (344), Expect = 8e-31
Identities = 72/145 (49%), Positives = 97/145 (66%), Gaps = 5/145 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA--LPSITYMAVNK-GEQWVSN 427
S P VGWG G+VYQKAY+EFFC + +L+ ++ +A SI+YMAV G + SN
Sbjct: 424 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 483
Query: 426 TA-QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEAD-PSRNL 253
Q VNAVTWGVFP EIIQPT+VD SF WKDEAF W+ W ++YPE D SR +
Sbjct: 484 IPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQV 542
Query: 252 LEEVKNSYYLVSLVENDYINGDIFA 178
L ++ Y+L ++V+ND++ GD+F+
Sbjct: 543 LNFIRQHYFLCTVVDNDFVAGDLFS 567
[58][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 137 bits (344), Expect = 8e-31
Identities = 72/145 (49%), Positives = 97/145 (66%), Gaps = 5/145 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA--LPSITYMAVNK-GEQWVSN 427
S P VGWG G+VYQKAY+EFFC + +L+ ++ +A SI+YMAV G + SN
Sbjct: 403 STDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSN 462
Query: 426 TA-QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEAD-PSRNL 253
Q VNAVTWGVFP EIIQPT+VD SF WKDEAF W+ W ++YPE D SR +
Sbjct: 463 IPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDDHQSRQV 521
Query: 252 LEEVKNSYYLVSLVENDYINGDIFA 178
L ++ Y+L ++V+ND++ GD+F+
Sbjct: 522 LNFIRQHYFLCTVVDNDFVAGDLFS 546
[59][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 135 bits (340), Expect = 2e-30
Identities = 66/135 (48%), Positives = 88/135 (65%), Gaps = 2/135 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALPSITYMAVNK-GEQWVSNT 424
S P GWG GY+ QKAYLEFF +K +A+ K P + Y +NK G +N
Sbjct: 466 STHPIYGWGDKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNA 525
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEE 244
+++ NAVTWG+F KEIIQPT+VDP SF VWKDEAF W WA+LY + SR ++ +
Sbjct: 526 DRSNPNAVTWGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKSREIIND 585
Query: 243 VKNSYYLVSLVENDY 199
+ ++YYLV+LV+NDY
Sbjct: 586 IADNYYLVNLVDNDY 600
[60][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 133 bits (334), Expect = 1e-29
Identities = 62/136 (45%), Positives = 85/136 (62%), Gaps = 1/136 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSN-TA 421
S + GWGGP GY+YQKAY E FCS E + +V K S+ AVN + T
Sbjct: 480 STHESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTE 539
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
V A+TWGVFP +EI+QPTI DP F VW +EAF W+ W+NLY S +L+E +
Sbjct: 540 LGGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDSFDLIETI 599
Query: 240 KNSYYLVSLVENDYIN 193
+++YYL ++++NDYI+
Sbjct: 600 RDTYYLCAIIDNDYIS 615
[61][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 133 bits (334), Expect = 1e-29
Identities = 69/146 (47%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S E + + ++ P +TY AV K +N
Sbjct: 440 STHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQF 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ WA Y PSR++L+E+
Sbjct: 500 EGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQL-GMEWARCYETGTPSRSILDEIM 558
Query: 237 NSYYLVSLVENDYINGD-IFAVFADL 163
N++YLV++V ND+ G+ IF V L
Sbjct: 559 NTWYLVNIVNNDFHRGETIFEVLKGL 584
[62][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 132 bits (333), Expect = 2e-29
Identities = 71/148 (47%), Positives = 89/148 (60%), Gaps = 1/148 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S E + ++ + P +TY AV K +N
Sbjct: 440 STHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPS 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ S WA Y PSR LLE++
Sbjct: 500 DAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGS-DWARCYEADTPSRLLLEDIM 558
Query: 237 NSYYLVSLVENDYINGD-IFAVFADL*E 157
S+YLV++V ND+ G+ ++ V DL E
Sbjct: 559 KSWYLVNIVNNDFHQGETLYEVLNDLQE 586
[63][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 132 bits (332), Expect = 2e-29
Identities = 68/146 (46%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + P +TY VNK + +NT
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA + + PSR ++++V
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+S+YLV++V ND+ DIF +F DL
Sbjct: 558 DSWYLVNIVNNDFHKTHDIFNIFKDL 583
[64][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 132 bits (331), Expect = 3e-29
Identities = 69/143 (48%), Positives = 89/143 (62%), Gaps = 1/143 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD P GWG GYVYQKAYLEFF + L+ ++ + +ITY +NK +NT
Sbjct: 441 SDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHS 500
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAFE + WA LY PS+ L+ E+
Sbjct: 501 DGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYEANSPSQKLITELM 559
Query: 237 NSYYLVSLVENDYINGD-IFAVF 172
++ +LV++V ND+ D IF F
Sbjct: 560 DTCFLVNVVHNDFHEPDAIFKPF 582
[65][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 131 bits (330), Expect = 4e-29
Identities = 68/146 (46%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + P +TY VNK + +NT
Sbjct: 331 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTD 390
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA + + PSR ++++V
Sbjct: 391 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPSRRIIQQVM 448
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+S+YLV++V ND+ DIF +F DL
Sbjct: 449 DSWYLVNIVNNDFHKTHDIFNIFKDL 474
[66][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 130 bits (327), Expect = 8e-29
Identities = 72/153 (47%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQK+YLE D ++ + + P +TY AV K + SN
Sbjct: 440 SSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTS 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ Y + PSR LLE V
Sbjct: 500 DGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDISSPSRALLEGVM 558
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL*ENQETT 142
N +YLV++V ND+ N IF + L N TT
Sbjct: 559 NDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTT 591
[67][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 130 bits (327), Expect = 8e-29
Identities = 66/146 (45%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE E + V+ + + P +TY A+NK + +NT+
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KE+IQPTIV+ SF WKDEAF WA + PSR L++ V
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+ +YLV++V ND+ DIF +F D+
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFNLFNDI 583
[68][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 130 bits (327), Expect = 8e-29
Identities = 67/146 (45%), Positives = 89/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S PT GWG GYVYQKAYLE S E + ++ + + P TY AVNK +N
Sbjct: 440 SSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPN 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDE F + WAN + A PSR ++++V
Sbjct: 500 EGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDE-FYRLGQQWANCHGGASPSRFVIQDVV 558
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YL+++V ND+ IF +F L
Sbjct: 559 DTWYLLNIVHNDFHATRGIFPIFDGL 584
[69][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 130 bits (327), Expect = 8e-29
Identities = 66/146 (45%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE E + V+ + + P +TY A+NK + +NT+
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KE+IQPTIV+ SF WKDEAF WA + PSR L++ V
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPSRQLIQRVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+ +YLV++V ND+ DIF +F D+
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFDLFNDI 583
[70][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 130 bits (327), Expect = 8e-29
Identities = 67/146 (45%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + P +TY VNK + +NT
Sbjct: 426 SSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTD 485
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA + + PSR ++++V
Sbjct: 486 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHGASSPSRRIIQQVM 543
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F DL
Sbjct: 544 DNWYLVNIVNNDFHKTHDIFNIFKDL 569
[71][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 129 bits (325), Expect = 1e-28
Identities = 65/146 (44%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE F S E + ++ + + P TY AVNK +N
Sbjct: 440 SSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPN 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDE F + WAN + PSR +++++
Sbjct: 500 EGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDE-FYRLGQQWANCHAGVSPSRYVIQDIV 558
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YL+++V ND+ IF +F L
Sbjct: 559 DTWYLLNIVHNDFHETRGIFPIFDGL 584
[72][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 128 bits (322), Expect = 3e-28
Identities = 68/146 (46%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S E + + + P ITY AV K +N
Sbjct: 440 STHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPS 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAF+ WA Y PSR L+EE+
Sbjct: 500 EGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQL-GLEWARCYDADTPSRLLIEEIM 558
Query: 237 NSYYLVSLVENDYIN-GDIFAVFADL 163
+ +YL+++V ND+ IF + DL
Sbjct: 559 DKWYLINIVNNDFHQPRTIFEILNDL 584
[73][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 128 bits (322), Expect = 3e-28
Identities = 69/143 (48%), Positives = 87/143 (60%), Gaps = 1/143 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
SD GWG GYVYQKAYLEFF L +++ + +ITY +NK +NT
Sbjct: 401 SDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHS 460
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEIIQPTIV+ SF WKDEA+E ++ WA LY PS+ L+ +
Sbjct: 461 EGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYEHDSPSQKLILNLM 519
Query: 237 NSYYLVSLVENDYINGD-IFAVF 172
+Y LV++V ND+ N D IF F
Sbjct: 520 ENYALVNVVHNDFHNPDAIFEPF 542
[74][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 128 bits (321), Expect = 4e-28
Identities = 68/146 (46%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE + E + +V+K + IT+ AVNK +N A
Sbjct: 440 STHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTN-AP 498
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWG++P KE+IQPTIV+ SF WK+EAF S WA YP SR L+++
Sbjct: 499 GGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYPAESESRKFLDDIF 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
N++YLV++V ND+ + IF +F+DL
Sbjct: 558 NNWYLVNIVHNDFHDSTGIFDLFSDL 583
[75][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 128 bits (321), Expect = 4e-28
Identities = 66/146 (45%), Positives = 89/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE E +D V+ + + +TY A NK + +NT+
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KE+IQPTIV+ SF WKDEA+ WA + PSR L++ V
Sbjct: 500 SP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDARSPSRQLIQRVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+ +YLV++V ND+ DIF +F DL
Sbjct: 558 DEWYLVNIVNNDFHKTHDIFDLFKDL 583
[76][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 128 bits (321), Expect = 4e-28
Identities = 66/146 (45%), Positives = 93/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S ++ V+ + + +TY VNK + +NT+
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P + PSR L+++V
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F +L
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLFKNL 583
[77][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 128 bits (321), Expect = 4e-28
Identities = 66/146 (45%), Positives = 93/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S ++ V+ + + +TY VNK + +NT+
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P + PSR L+++V
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F +L
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLFKNL 583
[78][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 127 bits (320), Expect = 5e-28
Identities = 67/135 (49%), Positives = 82/135 (60%), Gaps = 2/135 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGE--QWVSNT 424
S P VGWG P GY YQKAYLEFF S+ + + + + VN W +NT
Sbjct: 508 STDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDW-TNT 566
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEE 244
AVTWGVFP EI QPT+VDP SF VWKDEAF W +W+++Y E SR LLE+
Sbjct: 567 ETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSSRCLLEK 625
Query: 243 VKNSYYLVSLVENDY 199
+ N Y LV+LV+NDY
Sbjct: 626 IYNEYCLVTLVDNDY 640
[79][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 127 bits (320), Expect = 5e-28
Identities = 66/146 (45%), Positives = 92/146 (63%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S ++ V+ + + +TY VNK + +NT
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA +P + PSR L+++V
Sbjct: 500 SP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPSRRLIQQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F +L
Sbjct: 558 DTWYLVNIVNNDFHRTHDIFDLFKNL 583
[80][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 127 bits (318), Expect = 9e-28
Identities = 62/135 (45%), Positives = 90/135 (66%), Gaps = 2/135 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYMAVNKGEQWVSNT 424
S+ VGWG GYV+QKA++EFF ++++++ + EK + IT A N+ + +NT
Sbjct: 485 SEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNT 544
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEE 244
+ VNAVTWGVFP +EI Q TI++ SF WK+EAF+ W+ W+ LYP PSR LLE
Sbjct: 545 DKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EWSLLYPRNTPSRKLLEG 603
Query: 243 VKNSYYLVSLVENDY 199
+ N ++LVSL+ +DY
Sbjct: 604 IANEWWLVSLIHHDY 618
[81][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 126 bits (317), Expect = 1e-27
Identities = 64/146 (43%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE E +D ++ + + P +TY VNK + + + +
Sbjct: 441 STDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKARSDE 500
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWG+F +KEIIQPTIV+ SF WKDEA++ WA +P PSR L++ V
Sbjct: 501 GP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHPADSPSRKLIQRVM 558
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+ +Y++++V ND+ N DIF +F L
Sbjct: 559 DEWYILNIVNNDFHKNDDIFRLFDGL 584
[82][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 126 bits (316), Expect = 2e-27
Identities = 63/146 (43%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE F LD ++ + + P +TY AV K + +NT
Sbjct: 440 SSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EI+QPTIVD SF WKDEA+ WA + + PSR L++++
Sbjct: 500 SP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIM 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+++YLV++V ND+ N D+F +F L
Sbjct: 558 DNWYLVNIVNNDFHNTYDLFDLFNGL 583
[83][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 126 bits (316), Expect = 2e-27
Identities = 67/146 (45%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + +TY VNK + +NT
Sbjct: 440 SSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA + + SR L+E+V
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F DL
Sbjct: 558 DTWYLVNIVNNDFHKTHDIFNLFKDL 583
[84][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 126 bits (316), Expect = 2e-27
Identities = 67/146 (45%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + +TY VNK + +NT
Sbjct: 440 SSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NAVTWG+F +KEIIQPTIV+ SF WKDEA+ WA + + SR L+E+V
Sbjct: 500 SP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHAPSSLSRRLIEQVM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YLV++V ND+ DIF +F DL
Sbjct: 558 DTWYLVNIVNNDFHKTHDIFNLFKDL 583
[85][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 126 bits (316), Expect = 2e-27
Identities = 63/146 (43%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE F LD ++ + + P +TY AV K + +NT
Sbjct: 440 SSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EI+QPTIVD SF WKDEA+ WA + + PSR L++++
Sbjct: 500 SP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIM 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+++YLV++V ND+ N D+F +F L
Sbjct: 558 DNWYLVNIVNNDFHNTYDLFDLFNGL 583
[86][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 124 bits (312), Expect = 4e-27
Identities = 62/146 (42%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE F LD ++ + + P +TY AV K + +NT
Sbjct: 440 SSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA + + PSR L++++
Sbjct: 500 SP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHDASSPSRKLIQDIM 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+++YLV++V ND+ N D+F +F L
Sbjct: 558 DNWYLVNIVNNDFHNTYDLFDLFNGL 583
[87][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 124 bits (311), Expect = 6e-27
Identities = 57/128 (44%), Positives = 81/128 (63%), Gaps = 1/128 (0%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNK-GEQWVSNTAQADVNA 403
GWGG G VYQKAY E F S K + + + PS+ AVN G++ + V A
Sbjct: 447 GWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGGVTA 506
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYL 223
+TWGVFP +EI+QPTI DP +F +W +EAF W W NLY S +L++E++++YYL
Sbjct: 507 LTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLYEYGSESYDLVQEIRDTYYL 566
Query: 222 VSLVENDY 199
V+L++ND+
Sbjct: 567 VALIDNDF 574
[88][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 124 bits (310), Expect = 7e-27
Identities = 65/146 (44%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE F LD ++ + + +TY AV K + +NT
Sbjct: 440 SSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA + A PSR L++EV
Sbjct: 500 SP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAASPSRKLIQEVV 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+S+YLV++V ND+ N D+F +F L
Sbjct: 558 DSWYLVNIVNNDFHNTYDLFELFNGL 583
[89][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 124 bits (310), Expect = 7e-27
Identities = 65/143 (45%), Positives = 84/143 (58%), Gaps = 1/143 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG P GYV+QK Y+EFF L+ + E K L S++Y NK +N+
Sbjct: 443 SSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQY 502
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP +EIIQPTIV+ SF WKDEA+ + WAN Y SR LL +
Sbjct: 503 EIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAY-SLGMEWANAYSPDSISRKLLVSMM 561
Query: 237 NSYYLVSLVENDYING-DIFAVF 172
++L +V+ND+ NG +F VF
Sbjct: 562 KEWFLCVIVDNDFQNGQSLFDVF 584
[90][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 123 bits (309), Expect = 1e-26
Identities = 58/120 (48%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVNKGEQWVSNTA 421
S P VGWG GYVYQKAYLEFF S E + A+++ K P + Y VN + ++N
Sbjct: 497 STDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAP 556
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
NAVTWG+F +EI+QPT+VDP SF WKDEAF W WA LY + PSR +++ +
Sbjct: 557 DMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYI 616
[91][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 123 bits (308), Expect = 1e-26
Identities = 61/146 (41%), Positives = 91/146 (62%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE +D ++ + +A +TY AV K + +NT
Sbjct: 440 SSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +E++QPTIV+ SF WKDEA++ WA + + P+R LL+ +
Sbjct: 500 SP-NALTWGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEASSPTRKLLQGIM 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+S+YLV++V ND+ N D+F +F DL
Sbjct: 558 DSWYLVNIVNNDFHNTYDLFELFKDL 583
[92][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 123 bits (308), Expect = 1e-26
Identities = 67/148 (45%), Positives = 89/148 (60%), Gaps = 1/148 (0%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAV 400
GWG GYVYQK+YLE + + ++ + + P +T+ AV K + SN NAV
Sbjct: 446 GWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSDCPNAV 505
Query: 399 TWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLV 220
TWGVFP KEI+QPTIV+ SF WKDEAF WA+ Y PSR L++EV N +YLV
Sbjct: 506 TWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDANSPSRALIDEVMNEWYLV 564
Query: 219 SLVENDY-INGDIFAVFADL*ENQETTT 139
++V ND+ N IF + L E ++ TT
Sbjct: 565 NIVNNDFHQNATIFELLKGL-EVKDLTT 591
[93][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 122 bits (307), Expect = 2e-26
Identities = 61/146 (41%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE S +D V+ + + P +TY +NK + +N++
Sbjct: 440 SSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWG+F +KE+IQPTIV+ SF WKDEA+ WA + + PSR +++
Sbjct: 500 TP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDASSPSRKIIQNTM 557
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+++YL ++V ND+ DIF +F L
Sbjct: 558 DTWYLFNIVNNDFHKTHDIFDLFKGL 583
[94][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 122 bits (307), Expect = 2e-26
Identities = 62/146 (42%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE E ++ ++ + + P +TY +NK + + + +
Sbjct: 441 STDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRARSDE 500
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWG+F +KEIIQPTIV+ SF WKDEA++ WA +P PSR LL+ V
Sbjct: 501 GP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHPADSPSRKLLQRVM 558
Query: 237 NSYYLVSLVENDY-INGDIFAVFADL 163
+ +Y++++V ND+ N DIF +F L
Sbjct: 559 DEWYILNIVNNDFHKNDDIFRLFDGL 584
[95][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 122 bits (306), Expect = 2e-26
Identities = 59/136 (43%), Positives = 84/136 (61%), Gaps = 3/136 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALP-SITYMAVNKGEQW-VSN 427
S P VGWG P GY YQKAYLE F + E D +++ + P + Y A+NK + +N
Sbjct: 488 STDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTN 547
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W + YP+ S +++
Sbjct: 548 SEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIK 607
Query: 246 EVKNSYYLVSLVENDY 199
V + + LV+LV+ND+
Sbjct: 608 AVHDEFRLVTLVDNDF 623
[96][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 122 bits (306), Expect = 2e-26
Identities = 59/136 (43%), Positives = 84/136 (61%), Gaps = 3/136 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC-KALP-SITYMAVNKGEQW-VSN 427
S P VGWG P GY YQKAYLE F + E D +++ + P + Y A+NK + +N
Sbjct: 509 STDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTN 568
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W + YP+ S +++
Sbjct: 569 SEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIK 628
Query: 246 EVKNSYYLVSLVENDY 199
V + + LV+LV+ND+
Sbjct: 629 AVHDEFRLVTLVDNDF 644
[97][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 121 bits (304), Expect = 4e-26
Identities = 60/133 (45%), Positives = 78/133 (58%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG P GYVYQKAYLE + + E+ P +TY AV K +N
Sbjct: 435 STHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNATY 494
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPT+V+ SF WKDEAF+ WA + + PSR L++ +
Sbjct: 495 EGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQL-GMEWARCHDQNTPSRILIQSMM 553
Query: 237 NSYYLVSLVENDY 199
+YLV++V ND+
Sbjct: 554 QEWYLVNIVNNDF 566
[98][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 120 bits (302), Expect = 6e-26
Identities = 58/137 (42%), Positives = 86/137 (62%), Gaps = 4/137 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCS---KEKLDAVVEKCKALPSITYMAVNKGEQW-VS 430
S P VGWG P GY YQKAYLE F + EKL ++E+ + + Y A++K + +
Sbjct: 510 STDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPV-RVNYHAIDKDSSFDKT 568
Query: 429 NTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLL 250
N+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W + YP+ S ++
Sbjct: 569 NSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVI 628
Query: 249 EEVKNSYYLVSLVENDY 199
+ + +++ LV+LV+ND+
Sbjct: 629 KSIHDTFRLVTLVDNDF 645
[99][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 120 bits (302), Expect = 6e-26
Identities = 61/146 (41%), Positives = 89/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE LD ++ + + +TY AV+K + +NT
Sbjct: 440 SSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +E++QPTIV+ SF WKDEA+ WA + PSR L++ +
Sbjct: 500 SP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHAATSPSRKLIQGLV 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+S+YLV++V ND+ N D+F +F DL
Sbjct: 558 DSWYLVNIVNNDFHNTYDLFELFKDL 583
[100][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 120 bits (301), Expect = 8e-26
Identities = 59/128 (46%), Positives = 77/128 (60%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE + + + +V + + P +TY AV K +N
Sbjct: 440 SSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQS 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
NAVTWGVFP KEI+QPTIV+ SF WKDEAF WA+ + PSR L+E +
Sbjct: 500 DGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHSALSPSRGLIESIM 558
Query: 237 NSYYLVSL 214
+S+YLV++
Sbjct: 559 DSWYLVNI 566
[101][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 118 bits (296), Expect = 3e-25
Identities = 58/147 (39%), Positives = 87/147 (59%), Gaps = 14/147 (9%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCS---KEKLDAVVEKCKALPSITYMAVNKGEQWV-- 433
S P VGWG P GY YQKAYLE F + EKL ++E+ + + Y A++K ++
Sbjct: 560 STDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPV-RVNYHAIDKDVSYILN 618
Query: 432 ---------SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY 280
+N+ + AVTWGVFP EI QPT+VDP SF W+DEA++ W W + Y
Sbjct: 619 SHDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFY 678
Query: 279 PEADPSRNLLEEVKNSYYLVSLVENDY 199
P+ S +++ + +++ LV+LV+ND+
Sbjct: 679 PKESKSYGVIKSIHDTFRLVTLVDNDF 705
[102][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 118 bits (296), Expect = 3e-25
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 3/136 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---ITYMAVNKGEQWVSN 427
S P VG+G P G+V+QK+++E F S D +V + AL + ITY A N + SN
Sbjct: 538 STDPIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSN 597
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ N VTW VFP KEI+Q TI++ SF W++EAFE W+ W+ L+P+ SR L++
Sbjct: 598 LGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLLFPKKSASRQLID 656
Query: 246 EVKNSYYLVSLVENDY 199
E++ + +LV++V +DY
Sbjct: 657 EIREARWLVTVVHHDY 672
[103][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 118 bits (296), Expect = 3e-25
Identities = 53/129 (41%), Positives = 82/129 (63%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAV 400
GWG G+V+QKA++E F S +A+ ++ P ITY+A N ++ +N + NAV
Sbjct: 489 GWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAV 548
Query: 399 TWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLV 220
TWGVFP +EIIQ TI+ P SF W+DEA+ W WA LYP PS L++ ++ +LV
Sbjct: 549 TWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPAGTPSHKLIQSCIDNCWLV 607
Query: 219 SLVENDYIN 193
S++ +++++
Sbjct: 608 SVIHHNFLD 616
[104][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 117 bits (294), Expect = 5e-25
Identities = 59/146 (40%), Positives = 89/146 (60%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE LD ++ + + +TY AV+K + +NT
Sbjct: 440 SSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +E++QPTIV+ SF WKDEA+ WA + PSR L+++V
Sbjct: 500 SP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAGSPSRKLIQDVM 557
Query: 237 NSYYLVSLVENDYING-DIFAVFADL 163
+++YLV++V ND+ N ++F +F L
Sbjct: 558 DNWYLVNIVNNDFHNSFNLFELFDGL 583
[105][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 117 bits (294), Expect = 5e-25
Identities = 59/144 (40%), Positives = 85/144 (59%), Gaps = 2/144 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYMAVNKGEQWVSNT 424
S T GWG GYV+QK ++EFFC ++A+ ++ K + + Y N + SN
Sbjct: 466 SSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNV 525
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEE 244
+ NAVTWGVFP +EI Q TI++ SF WKDEA++ W+ SWA+LY R LL++
Sbjct: 526 PEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAYDIWN-SWASLYHPDSAERQLLQK 584
Query: 243 VKNSYYLVSLVENDYINGDIFAVF 172
V N +LVS+V ++Y N + F
Sbjct: 585 VANERWLVSIVHHEYKNPNALWTF 608
[106][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 117 bits (294), Expect = 5e-25
Identities = 60/146 (41%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQKAYLE +D ++ + + +TY AV+K + +NT
Sbjct: 440 SSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EI+QPTIV+ SF WKDEA+ WA + + PSR L++ V
Sbjct: 500 SP-NALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDTSSPSRKLIQGVM 557
Query: 237 NSYYLVSLVENDYIN-GDIFAVFADL 163
++++LV++V ND+ N ++F +F DL
Sbjct: 558 DNWHLVNIVNNDFHNTSNLFDLFKDL 583
[107][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 116 bits (291), Expect = 1e-24
Identities = 59/146 (40%), Positives = 86/146 (58%), Gaps = 1/146 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G+VYQKAYLE +D ++ + + +TY A NK + +NT
Sbjct: 440 SSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNTRD 499
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ NA+TWG+F +EIIQPTIV+ SF WKDEA+ W+ + A PSR L++ V
Sbjct: 500 SP-NALTWGIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHDAASPSRQLIQHVM 557
Query: 237 NSYYLVSLVENDYINGD-IFAVFADL 163
+YLV++V+ND+ + +F +F L
Sbjct: 558 EDWYLVNIVDNDFHRSNAVFELFNGL 583
[108][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 116 bits (290), Expect = 2e-24
Identities = 60/160 (37%), Positives = 98/160 (61%), Gaps = 21/160 (13%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP--------SITYMAVNKGEQWVSNT 424
GWG G+VYQK YLEFF + L ++ + L ++T+ AVN + ++N+
Sbjct: 444 GWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNS 503
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEAD-------- 268
+ D+NAVTWG+FP KE++QPTIV+ SF WKDEAF + ++W++L+ + D
Sbjct: 504 KEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KAWSSLFKDQDQDEFEVLR 562
Query: 267 --PSRNLLEEVKNSYYLVSLVENDYI---NGDIFAVFADL 163
+R +L+++ + Y+LV++V+N+Y+ N IF +F L
Sbjct: 563 DSKTRAVLDKLHDEYFLVNIVDNNYVQNPNVKIFDLFKTL 602
[109][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 114 bits (284), Expect = 8e-24
Identities = 54/135 (40%), Positives = 81/135 (60%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG G V+QKA++E F + + L + K P +TY A N ++++N +
Sbjct: 496 SADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPK 555
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+AVTWGV+P +EIIQ TI+ SF W E+F+ W WANLY + PSR LLE
Sbjct: 556 DGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSKNTPSRKLLENCI 614
Query: 237 NSYYLVSLVENDYIN 193
N +LV+++ +D+++
Sbjct: 615 NDRWLVTVIHHDFMD 629
[110][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 113 bits (283), Expect = 1e-23
Identities = 59/133 (44%), Positives = 82/133 (61%), Gaps = 3/133 (2%)
Frame = -3
Query: 582 VGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ-ADVN 406
VGWG GYVYQK YLEF K KL + + +PS+TY AV+ ++ SN N
Sbjct: 455 VGWGPNNGYVYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSNHPDDTAAN 514
Query: 405 AVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRN--LLEEVKNS 232
AVTWG+FP +E++QPTIV+ SF WK+E F+ W + E + S + LLE V +
Sbjct: 515 AVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDILD-EWKRIMGENNHSESVALLESVISD 573
Query: 231 YYLVSLVENDYIN 193
Y LV++V+NDY++
Sbjct: 574 YLLVNIVDNDYVS 586
[111][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 112 bits (279), Expect = 3e-23
Identities = 59/137 (43%), Positives = 79/137 (57%), Gaps = 4/137 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYMAVN--KGEQWVS 430
S VGWG GYV+QK ++EFFC ++ +D + + + + Y A N + S
Sbjct: 451 SGDKVVGWGPRGGYVFQKGFVEFFCEEKDMDVIERRVERNGHGWVHYFAGNYKADGECRS 510
Query: 429 NTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLL 250
N + NAVTWGVFP +EI Q TI++ SF WKDEAF WS WA+ Y R LL
Sbjct: 511 NVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWASFYRPGSEERKLL 569
Query: 249 EEVKNSYYLVSLVENDY 199
E V+N +LVS+V +DY
Sbjct: 570 EGVRNERWLVSIVHHDY 586
[112][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 111 bits (278), Expect = 4e-23
Identities = 61/139 (43%), Positives = 85/139 (61%), Gaps = 4/139 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS-ITYMAVNKGEQWVSNTA 421
S P VGWG GYVYQK YLEF +EKL E C+ +TY A++ + +N
Sbjct: 454 STDPVVGWGPTKGYVYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHP 513
Query: 420 Q-ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE--ADPSRNLL 250
+ + NAVTWGVFP EI+QPTIV+ ASF WK+E F T + W + E A S NL+
Sbjct: 514 EDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFF-TILKEWKLTFVEHKATESVNLV 572
Query: 249 EEVKNSYYLVSLVENDYIN 193
+ ++Y L+++V+ND+I+
Sbjct: 573 NHIIDNYVLINVVDNDFIS 591
[113][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 111 bits (278), Expect = 4e-23
Identities = 60/152 (39%), Positives = 83/152 (54%), Gaps = 15/152 (9%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---------ITYMAVNKG 445
S GWG GYVYQK YLEFFC K+ + +++ I+Y AVNK
Sbjct: 445 SSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKN 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEA---FETWSRSWANLYPE 274
+SN D+NAVTWGVFP +EI+QPTIV+ SF WKDE F WS+ E
Sbjct: 505 GNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFSEWSKISGMFDAE 564
Query: 273 ADPSRN---LLEEVKNSYYLVSLVENDYINGD 187
D ++ L+ ++ ++ L +LV ND++ G+
Sbjct: 565 KDKIQHFNELMSQITENFVLCNLVNNDFLQGN 596
[114][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 110 bits (276), Expect = 7e-23
Identities = 54/150 (36%), Positives = 83/150 (55%), Gaps = 13/150 (8%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITYMAVNKGEQWVSN 427
S PT GWG G+V+QKA++EFF + +K + + + A+N +VS+
Sbjct: 535 SSDPTFGWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSS 594
Query: 426 TA----------QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 277
+A NAVTWGVFP KEI+ PTI++ SF W +EAF W WA +Y
Sbjct: 595 DTAGSLEAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIYG 653
Query: 276 EADPSRNLLEEVKNSYYLVSLVENDYINGD 187
+ S LLE+++ +LV+++ +D+I+ D
Sbjct: 654 KGSESEKLLEKIRGDSWLVNIIHHDFIDSD 683
[115][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 110 bits (276), Expect = 7e-23
Identities = 63/149 (42%), Positives = 83/149 (55%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVN-KGE--- 442
SD PT GWG P G+V+QK ++EFFC + V++ A + + A N KGE
Sbjct: 543 SDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFES 602
Query: 441 QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
++ A AD VNAVTWGVF KEI+ PTI++ SF W +EAF W W
Sbjct: 603 SLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRR 661
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP P+ LLEEVKN +LV +V D+
Sbjct: 662 VYPRGTPTERLLEEVKNDVWLVCVVGQDF 690
[116][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 110 bits (274), Expect = 1e-22
Identities = 59/150 (39%), Positives = 81/150 (54%), Gaps = 13/150 (8%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSK---EKLDAVVEKCKALPSITYMAVNKGEQWVSN 427
S T GWG P G+V+QK+++EFF E L A + + + + A N +VS+
Sbjct: 516 SSDATFGWGPPNGFVFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSS 575
Query: 426 T----------AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 277
A NAVTWGVFP KEII PTI++ SF W +EAF W WA +Y
Sbjct: 576 DIGGHVDGSTEASPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYG 634
Query: 276 EADPSRNLLEEVKNSYYLVSLVENDYINGD 187
S LL +K+ Y+LV+L+ +DY+N D
Sbjct: 635 RGSESEKLLNGIKDDYWLVNLIHHDYVNRD 664
[117][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 110 bits (274), Expect = 1e-22
Identities = 54/134 (40%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEK---CKALPSITYMAVNKGEQWVSNTAQADV 409
GWG G+VYQKA++E F +++ +++ +Y A + + +N
Sbjct: 505 GWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPHSS 564
Query: 408 NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSY 229
N VTWGVFP ++IQ TI++ SF W+DEAF WS WA L+P PS LL EV + Y
Sbjct: 565 NVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPSNTLLREVHSDY 623
Query: 228 YLVSLVENDYINGD 187
YLVS+V +D+I D
Sbjct: 624 YLVSIVHHDFIETD 637
[118][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 110 bits (274), Expect = 1e-22
Identities = 63/149 (42%), Positives = 83/149 (55%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVN-KGE--- 442
SD PT GWG P G+V+QK ++EFFC + V++ A + + A N KGE
Sbjct: 516 SDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFES 575
Query: 441 QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
++ A AD VNAVTWGVF KEI+ PTI++ SF W +EAF W W
Sbjct: 576 SLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRR 634
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP P+ LLEEVKN +LV +V D+
Sbjct: 635 VYPRGTPTERLLEEVKNDVWLVCVVGQDF 663
[119][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 110 bits (274), Expect = 1e-22
Identities = 63/149 (42%), Positives = 83/149 (55%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVN-KGE--- 442
SD PT GWG P G+V+QK ++EFFC + V++ A + + A N KGE
Sbjct: 516 SDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFES 575
Query: 441 QWVSNTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
++ A AD VNAVTWGVF KEI+ PTI++ SF W +EAF W W
Sbjct: 576 SLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRR 634
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP P+ LLEEVKN +LV +V D+
Sbjct: 635 VYPRGTPTERLLEEVKNDVWLVCVVGQDF 663
[120][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 108 bits (270), Expect = 3e-22
Identities = 57/150 (38%), Positives = 81/150 (54%), Gaps = 13/150 (8%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA---LPSITYMAVNKGEQWVSN 427
S T GWG P G+V+QK+++EFF + + EK + S+ + A N +VS+
Sbjct: 518 SSDGTFGWGPPNGFVFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSS 577
Query: 426 T----------AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP 277
A NAVTWGVFP KEII PTI++ SF W +EAF W WA +Y
Sbjct: 578 DKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYG 636
Query: 276 EADPSRNLLEEVKNSYYLVSLVENDYINGD 187
S LL +K+ Y+LV+L+ +D++ D
Sbjct: 637 RGSDSEKLLSGIKDEYWLVNLIHHDFVEKD 666
[121][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 108 bits (270), Expect = 3e-22
Identities = 53/133 (39%), Positives = 82/133 (61%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALPS-ITYMAVNKGEQWVSNTAQADVN 406
GWG P GYVYQK+++E F K++ + ++ K + L S ++Y + E + +N + +
Sbjct: 521 GWGPPGGYVYQKSFVEMFVHKQQWELEIKPKLEPLGSKVSYYVGDSAETFYTNLDSSCSS 580
Query: 405 AVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYY 226
VTWGVFP E++Q TIV+ SF W+DEAF W W+ L+P S LL+++ YY
Sbjct: 581 VVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKLFPRNSRSNTLLKQMHRDYY 639
Query: 225 LVSLVENDYINGD 187
LVS+V +D+ + D
Sbjct: 640 LVSIVHHDFSDCD 652
[122][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 108 bits (270), Expect = 3e-22
Identities = 58/154 (37%), Positives = 88/154 (57%), Gaps = 17/154 (11%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL---------PSITYMAVNKG 445
S GWG GYVYQK YLEFFC K+ + ++++ + I+Y AV+K
Sbjct: 445 SSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKD 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEA---FETWSRSWANLYPE 274
+N D+NAVTWGVFP +EI+QPTIV+ SF WKDE F W++ ++ E
Sbjct: 505 GNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWAKIASSNLVE 564
Query: 273 ADPSR-----NLLEEVKNSYYLVSLVENDYINGD 187
AD ++ L+++ + + L +LV ND+++G+
Sbjct: 565 ADQTQVNEFVRLMKKFGDEFVLCNLVNNDFVDGN 598
[123][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 108 bits (269), Expect = 4e-22
Identities = 59/162 (36%), Positives = 88/162 (54%), Gaps = 25/162 (15%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEK---LDAVVEKCKALPSITYMAVNKGEQWVSN 427
SD T GWG G+V+QKA++EFF L+A +++ ++ + A N +VS
Sbjct: 513 SDDGTFGWGPENGFVFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVST 572
Query: 426 ---------------TAQAD-------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF 313
TA+AD NAVTWGVFP KEI+ PTI++ SF W +EAF
Sbjct: 573 DTINFRARMAAEAEGTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAF 632
Query: 312 ETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGD 187
WS WA +Y + ++ LLE++K +LV+++ +DY+ D
Sbjct: 633 GIWS-EWAKIYGKGSDTQKLLEDLKEDLWLVNVIHHDYLEKD 673
[124][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 107 bits (267), Expect = 7e-22
Identities = 51/137 (37%), Positives = 77/137 (56%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYV+QK ++EFF + A+ + A +TY A N + +++ +
Sbjct: 401 STDPVFGWGPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEE 460
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
+ VN VTWG F KEI+ PTI++ SF W +EAF W R W +YP S LL + +
Sbjct: 461 S-VNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPTKSASGKLLGQTR 518
Query: 237 NSYYLVSLVENDYINGD 187
+LV+++ D++ GD
Sbjct: 519 EDVWLVNVIWGDFVQGD 535
[125][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 107 bits (266), Expect = 9e-22
Identities = 53/134 (39%), Positives = 77/134 (57%), Gaps = 5/134 (3%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSN-----TAQA 415
GWG G +YQK+++E F KE ++ K + ++TY NK + SN +
Sbjct: 497 GWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKL 556
Query: 414 DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKN 235
NAVTWGVFP+KE++QPT++D SF W +EAF W WA Y + S LL +
Sbjct: 557 SKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYE 615
Query: 234 SYYLVSLVENDYIN 193
+Y LVS++ +D+IN
Sbjct: 616 NYVLVSMIHHDFIN 629
[126][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 107 bits (266), Expect = 9e-22
Identities = 53/134 (39%), Positives = 77/134 (57%), Gaps = 5/134 (3%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSN-----TAQA 415
GWG G +YQK+++E F KE ++ K + ++TY NK + SN +
Sbjct: 497 GWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKL 556
Query: 414 DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKN 235
NAVTWGVFP+KE++QPT++D SF W +EAF W WA Y + S LL +
Sbjct: 557 SKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKSFELLNSIYE 615
Query: 234 SYYLVSLVENDYIN 193
+Y LVS++ +D+IN
Sbjct: 616 NYVLVSMIHHDFIN 629
[127][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 106 bits (265), Expect = 1e-21
Identities = 59/167 (35%), Positives = 93/167 (55%), Gaps = 22/167 (13%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKE---KLDAVVEKC-----KALPSITYMAVNKGE 442
S+ GWG GYV+QK YLEFFC ++ KL +EK ++ +TY A +K
Sbjct: 185 SNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNG 244
Query: 441 QWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY------ 280
+ +NT + D+NAVTWGVFP +EI+QPTIV+ SF WKDE + + W ++Y
Sbjct: 245 ELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITS 303
Query: 279 ------PEADPSRNLLEEVKNSYYLVSLVENDYINGD--IFAVFADL 163
+ + L E + + L ++V N++++ D +F++F D+
Sbjct: 304 DETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDLVLFSIFDDI 350
[128][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 106 bits (265), Expect = 1e-21
Identities = 59/167 (35%), Positives = 93/167 (55%), Gaps = 22/167 (13%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKE---KLDAVVEKC-----KALPSITYMAVNKGE 442
S+ GWG GYV+QK YLEFFC ++ KL +EK ++ +TY A +K
Sbjct: 185 SNDKVYGWGPKNGYVFQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNG 244
Query: 441 QWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY------ 280
+ +NT + D+NAVTWGVFP +EI+QPTIV+ SF WKDE + + W ++Y
Sbjct: 245 ELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVYDSHITS 303
Query: 279 ------PEADPSRNLLEEVKNSYYLVSLVENDYINGD--IFAVFADL 163
+ + L E + + L ++V N++++ D +F++F D+
Sbjct: 304 DETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDSVLFSIFDDI 350
[129][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 106 bits (265), Expect = 1e-21
Identities = 59/153 (38%), Positives = 83/153 (54%), Gaps = 18/153 (11%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---------ITYMAVNKG 445
S GWG GYVYQK YLEFFC K+ L ++ + I+Y AV+K
Sbjct: 445 SSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKN 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYP---- 277
+N D+NAVTWGVFP +EI+QPTIV+ SF WKDE + ++ W N+
Sbjct: 505 GNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWTNILQSNLV 563
Query: 276 EADPSR-----NLLEEVKNSYYLVSLVENDYIN 193
+AD + +L+ N++ L +LV ND+I+
Sbjct: 564 DADKDKISGFVDLITNFSNNFVLCNLVNNDFID 596
[130][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 106 bits (264), Expect = 2e-21
Identities = 60/138 (43%), Positives = 78/138 (56%), Gaps = 4/138 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA-LPSITYMAVNKGEQWVSNTA 421
S P VGWG GYVYQK YLEF K L A A P++TY AV+ + SN
Sbjct: 453 SADPIVGWGPANGYVYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHP 512
Query: 420 Q-ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE--ADPSRNLL 250
NAVTWG+FP +E++QPTIV+ ASF WKDE + W + E A S LL
Sbjct: 513 DDTQANAVTWGIFPGREVLQPTIVEKASFLAWKDEFYRILD-DWRLSFDENGAADSAALL 571
Query: 249 EEVKNSYYLVSLVENDYI 196
+ + Y LV++V+ND++
Sbjct: 572 AHLTSDYALVNIVDNDFV 589
[131][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 106 bits (264), Expect = 2e-21
Identities = 54/138 (39%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWV-SNTA 421
SD GWG GYV+QK++ EFF S E+ + A + V K ++ V +N +
Sbjct: 480 SDDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVS 539
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
+ N VTWGVFP +EI+Q TI+ SF+ W++EAF WS W LY + S LL+++
Sbjct: 540 ERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALYKKNTASFKLLDKI 598
Query: 240 KNSYYLVSLVENDYINGD 187
N Y LV+++ +DY+ D
Sbjct: 599 INEYLLVTVIHHDYVEED 616
[132][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 105 bits (263), Expect = 2e-21
Identities = 57/154 (37%), Positives = 87/154 (56%), Gaps = 17/154 (11%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL---------PSITYMAVNKG 445
S GWG GYVYQK YLEFFC K+ + +++ + I+Y AV+K
Sbjct: 445 SSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAFISYYAVDKD 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEA---FETWSRSWANLYPE 274
+N D+NAVTWGVFP +EI+QPTIV+ SF WKDE F W++ ++ E
Sbjct: 505 GNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWAKIASSNLVE 564
Query: 273 ADPSR-----NLLEEVKNSYYLVSLVENDYINGD 187
A+ ++ L+++ + + L +LV ND+++G+
Sbjct: 565 ANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGN 598
[133][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 105 bits (263), Expect = 2e-21
Identities = 53/134 (39%), Positives = 78/134 (58%), Gaps = 5/134 (3%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSN-----TAQA 415
GWG G +YQK+++E F KE ++ K + ++TY +K + SN A+
Sbjct: 497 GWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKL 556
Query: 414 DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKN 235
NAVTWGVFP+KE++QPT++D SF W +EAF W WA Y + S LL +
Sbjct: 557 SKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWARCYKKNSKSFELLNSIYE 615
Query: 234 SYYLVSLVENDYIN 193
+Y LVS++ +D+IN
Sbjct: 616 NYVLVSIIHHDFIN 629
[134][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 105 bits (262), Expect = 3e-21
Identities = 54/139 (38%), Positives = 81/139 (58%), Gaps = 5/139 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSK---EKLDAVVEKCKALPSITYMAVNKGEQWVSN 427
S +GWG G ++QK+++EFF K E+L +++K + +ITY N + +N
Sbjct: 453 SSDSILGWGPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTN 512
Query: 426 TAQ--ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNL 253
+ A+TWGVFP+KE++QPT++D SF W +EAF W WA Y PS L
Sbjct: 513 MPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWARCYAPDSPSYRL 571
Query: 252 LEEVKNSYYLVSLVENDYI 196
L + + YYLVS+V N+Y+
Sbjct: 572 LAGIHSDYYLVSIVHNNYL 590
[135][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 105 bits (262), Expect = 3e-21
Identities = 52/137 (37%), Positives = 75/137 (54%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYV+QK ++EFF + A K +A +T+ A N + ++
Sbjct: 511 STDPIFGWGPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEASQED 570
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
VN VTWG F KEI+ PTI++ SF W DEAF W + W +YP S LL E+
Sbjct: 571 G-VNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYPPRSGSSVLLGELS 628
Query: 237 NSYYLVSLVENDYINGD 187
+LV+++ D++NG+
Sbjct: 629 KDVWLVNVIWGDFVNGE 645
[136][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 105 bits (261), Expect = 4e-21
Identities = 53/131 (40%), Positives = 78/131 (59%), Gaps = 2/131 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKL-DAVVEKCKALPSITYMAVNKGEQWVSNTA-QADVN 406
GWG GYVYQKA++E F +K++ + ++ + S+T+ + + +N N
Sbjct: 456 GWGPSEGYVYQKAFVEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSN 515
Query: 405 AVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYY 226
+VTWG FP KEI+Q TI+ SF W +EAF W R W LYP+ S NLL + N++Y
Sbjct: 516 SVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLYPKNTASYNLLGSIINNFY 574
Query: 225 LVSLVENDYIN 193
LV+L+ +DY N
Sbjct: 575 LVTLINHDYAN 585
[137][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 104 bits (260), Expect = 5e-21
Identities = 53/133 (39%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALPS-ITYMAVNKGEQWVSNTAQADVN 406
GWG G +YQKA++E F KE+ + V++ K ++ +Y + + +N N
Sbjct: 510 GWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTGYFETNLQPKSSN 569
Query: 405 AVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYY 226
AVTWGVFP E++Q TIV+ SF W+DEAF W W+ L+P+ P L ++ YY
Sbjct: 570 AVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTPENTFLRKMHRDYY 628
Query: 225 LVSLVENDYINGD 187
LVS+V +D+IN D
Sbjct: 629 LVSIVHHDFINPD 641
[138][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 103 bits (257), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVNKGEQWVS 430
SD P GWG P G+V+QK ++EFFC + ++ + + A N + S
Sbjct: 524 SDDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFES 583
Query: 429 N----TAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
+ T+ AD VNAVTWGVF KEI+ PTI++ SF W DEA+ W W
Sbjct: 584 SLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRR 642
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP P+ LEE KN +LV +V D+
Sbjct: 643 IYPRGSPTERFLEETKNDVWLVCVVGQDF 671
[139][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 103 bits (257), Expect = 1e-20
Identities = 55/134 (41%), Positives = 78/134 (58%), Gaps = 3/134 (2%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVE-KCKALP--SITYMAVNKGEQWVSNTAQADV 409
GWG GYVYQKA++E F K++ +A+V+ K P +Y + + SN
Sbjct: 505 GWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSS 564
Query: 408 NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSY 229
N VTWGVFP +IQ TIV+ SF W+DEAF W WA L+P + S + L++V ++Y
Sbjct: 565 NVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAKLFPSNELSNSFLKQVHSTY 623
Query: 228 YLVSLVENDYINGD 187
LVS+V +D+ D
Sbjct: 624 CLVSIVHHDFSETD 637
[140][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 103 bits (256), Expect = 1e-20
Identities = 57/139 (41%), Positives = 78/139 (56%), Gaps = 4/139 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYVYQK YLEF KEKL + + +TY AV+ +N
Sbjct: 451 SSHPVHGWGPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQD 510
Query: 417 AD-VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWANLYPEADPSRNLL 250
NAVTWG+FP +E++QPTIV+ SF WK E + E W ++ N D S LL
Sbjct: 511 GTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFIN--HRCDQSVKLL 568
Query: 249 EEVKNSYYLVSLVENDYIN 193
+ + + Y LV++V+ND+I+
Sbjct: 569 QHLIDDYVLVNIVDNDFIS 587
[141][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 102 bits (255), Expect = 2e-20
Identities = 54/133 (40%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ-ADVNA 403
GWG GYVYQK YLEF K KL +++ K +TY A++ +SN + NA
Sbjct: 458 GWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNA 517
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP-SRNLLEEVKNSYY 226
VTWG+FP +EI+QPTIV+ SF WK+E + + N+ P S ++ + + Y
Sbjct: 518 VTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYC 577
Query: 225 LVSLVENDYINGD 187
LV++V+NDYI+ D
Sbjct: 578 LVNIVDNDYISPD 590
[142][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 102 bits (255), Expect = 2e-20
Identities = 54/133 (40%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ-ADVNA 403
GWG GYVYQK YLEF K KL +++ K +TY A++ +SN + NA
Sbjct: 269 GWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNA 328
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP-SRNLLEEVKNSYY 226
VTWG+FP +EI+QPTIV+ SF WK+E + + N+ P S ++ + + Y
Sbjct: 329 VTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYC 388
Query: 225 LVSLVENDYINGD 187
LV++V+NDYI+ D
Sbjct: 389 LVNIVDNDYISPD 401
[143][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 102 bits (255), Expect = 2e-20
Identities = 54/133 (40%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ-ADVNA 403
GWG GYVYQK YLEF K KL +++ K +TY A++ +SN + NA
Sbjct: 458 GWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNA 517
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP-SRNLLEEVKNSYY 226
VTWG+FP +EI+QPTIV+ SF WK+E + + N+ P S ++ + + Y
Sbjct: 518 VTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYC 577
Query: 225 LVSLVENDYINGD 187
LV++V+NDYI+ D
Sbjct: 578 LVNIVDNDYISPD 590
[144][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 102 bits (255), Expect = 2e-20
Identities = 54/133 (40%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ-ADVNA 403
GWG GYVYQK YLEF K KL +++ K +TY A++ +SN + NA
Sbjct: 458 GWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNA 517
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP-SRNLLEEVKNSYY 226
VTWG+FP +EI+QPTIV+ SF WK+E + + N+ P S ++ + + Y
Sbjct: 518 VTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYC 577
Query: 225 LVSLVENDYINGD 187
LV++V+NDYI+ D
Sbjct: 578 LVNIVDNDYISPD 590
[145][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 101 bits (251), Expect = 5e-20
Identities = 55/145 (37%), Positives = 82/145 (56%), Gaps = 6/145 (4%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQAD-VNA 403
GWG GYVYQK YLEF EK++ + ++ +TY AV+ + SN NA
Sbjct: 458 GWGPKDGYVYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANA 517
Query: 402 VTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWANLYPEADPSRNLLEEVKNS 232
VTWG+FP +E++QPTIV+ SF WK+E + E W W S ++ + ++
Sbjct: 518 VTWGIFPGREVLQPTIVEKVSFLAWKEEFYRILEEW--KWNFQENNELKSAEFIQHIIDN 575
Query: 231 YYLVSLVENDYING--DIFAVFADL 163
Y LV++V+NDYI+ +I+ V +L
Sbjct: 576 YMLVNIVDNDYISSTDEIYNVLINL 600
[146][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 100 bits (250), Expect = 7e-20
Identities = 51/133 (38%), Positives = 73/133 (54%), Gaps = 2/133 (1%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS--ITYMAVNKGEQWVSNTAQADVN 406
GWG P G VYQKA++E F K + +A ++ P +Y + + SN A +
Sbjct: 496 GWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSS 555
Query: 405 AVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYY 226
VTWGVFP +I+Q TI++ SF W+DEAF W SW+ L+P P L + Y
Sbjct: 556 VVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWSKLFPRNSPHNAFLRGIHRDYC 614
Query: 225 LVSLVENDYINGD 187
LVS+V +D+ + D
Sbjct: 615 LVSIVHHDFSSVD 627
[147][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 100 bits (250), Expect = 7e-20
Identities = 51/135 (37%), Positives = 80/135 (59%), Gaps = 2/135 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS-ITYMAVN-KGEQWVSNT 424
S PT G+G GY++QKA++E F ++ +A+V+ + + +TY A + +N
Sbjct: 442 STDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNL 501
Query: 423 AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEE 244
+N VTWGVFP E+ Q TI++ ASF W+DEAF W R W L+P +R+LL
Sbjct: 502 TTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFPPNSATRSLLRR 560
Query: 243 VKNSYYLVSLVENDY 199
+ + +LV++V +DY
Sbjct: 561 IHDERWLVTVVHHDY 575
[148][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 100 bits (250), Expect = 7e-20
Identities = 56/142 (39%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA-VVEKCKALPS---ITYMAVNKGEQWVS 430
S GWG G+V+QK+++E F KE+ + K K + ITY A + + S
Sbjct: 490 SSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQS 549
Query: 429 NT-----AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP 265
N + NAVTWGVFP++E++QPTI+D SF W +EAF WS WA Y +
Sbjct: 550 NLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS-EWARCYKKNSV 608
Query: 264 SRNLLEEVKNSYYLVSLVENDY 199
S NLL + YYLVSL+ +++
Sbjct: 609 SYNLLNSINGDYYLVSLIYHNF 630
[149][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 100 bits (250), Expect = 7e-20
Identities = 57/149 (38%), Positives = 81/149 (54%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVN-KGEQWV 433
SD+ T GWG P G+V+QK ++EFFC + + V++ A + + A N KGE
Sbjct: 517 SDNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQS 576
Query: 432 S---NTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
S TA +D VNAVTWGVF KEI+ PTI++ SF W +EA+ W W
Sbjct: 577 SLPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWRR 635
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP + ++E KN +LV +V D+
Sbjct: 636 IYPRGSATERFIDETKNDVWLVCVVGQDF 664
[150][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 100 bits (249), Expect = 9e-20
Identities = 59/149 (39%), Positives = 86/149 (57%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA---VVEKCKALPS---ITYMAVNKGEQW 436
S+ GWG G+VYQK YLEF K+KL +VEK A + ITY AV+K
Sbjct: 447 SNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNL 506
Query: 435 VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETW-----SRSWANLY 280
+N+ D+NAVTWGVFP +EI+QPTIV+ SF WKDE + + W S++ ++
Sbjct: 507 HTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWITIFHSKAITDIV 566
Query: 279 PEADPSR--NLLEEVKNSYYLVSLVENDY 199
PE ++ +L++ ++ L + V ND+
Sbjct: 567 PEDKINKFDDLIKSFGENFVLCNFVNNDF 595
[151][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 100 bits (248), Expect = 1e-19
Identities = 49/108 (45%), Positives = 62/108 (57%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAV 400
GWG GYVYQK+YLE + ++ + + P +TY AV K N NAV
Sbjct: 154 GWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAV 213
Query: 399 TWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRN 256
TWGVFP KEI+QPTIV+ SF WKDEAF WA+ + ++ PS N
Sbjct: 214 TWGVFPGKEIVQPTIVEGISFVAWKDEAFRL-GLDWAHCFEQSSPSLN 260
[152][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 99.8 bits (247), Expect = 2e-19
Identities = 49/137 (35%), Positives = 73/137 (53%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S PT GWG G+V+QKA++EFF A+ ++ +N+ E +
Sbjct: 517 SSDPTFGWGPQNGFVFQKAFVEFFLPLADWAALEKR-----------LNRPEMEGRRERE 565
Query: 417 ADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVK 238
A NAV+WGVFP KEI+ PTI++ SF W +EAF W W +Y + S LE V
Sbjct: 566 ASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSESERFLERVL 624
Query: 237 NSYYLVSLVENDYINGD 187
+LV+++ +D++ D
Sbjct: 625 ADTWLVNIIHHDFLETD 641
[153][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 99.8 bits (247), Expect = 2e-19
Identities = 61/161 (37%), Positives = 81/161 (50%), Gaps = 24/161 (14%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS------------ITYMAV 454
S GWG GYVYQK YLEFFC K D +V+ + + I+Y AV
Sbjct: 446 SSEKIFGWGPKNGYVYQKQYLEFFCHK---DIIVKLLQTIDDYNNNQGDASSAIISYYAV 502
Query: 453 NKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSW-----A 289
+ +N D+NAVTWGVFP +EI+QPTIV+ SF WKDE + +S W +
Sbjct: 503 DLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFS-EWRKVLTS 561
Query: 288 NLYPEADPSR-------NLLEEVKNSYYLVSLVENDYINGD 187
NL D + L+ E Y L +LV ND+I+ +
Sbjct: 562 NLADVKDEDKKNLHKFEKLMTEFSEDYVLCNLVNNDFIDSN 602
[154][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 99.4 bits (246), Expect = 2e-19
Identities = 53/142 (37%), Positives = 73/142 (51%), Gaps = 5/142 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKE-----KLDAVVEKCKALPSITYMAVNKGEQWV 433
S + GWG G VYQKA++E F K + +E+ +TY A + +
Sbjct: 503 STNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKAIEQY-GRAKLTYYANDSQGNFE 561
Query: 432 SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNL 253
+N N VTWGVF ++IQ TIV SF W DEAF W WA L+P + +L
Sbjct: 562 TNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEWAKLFPRNTSTNSL 620
Query: 252 LEEVKNSYYLVSLVENDYINGD 187
L ++ Y L+S+V +DYIN D
Sbjct: 621 LRQIHQEYCLISIVHHDYINPD 642
[155][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 99.4 bits (246), Expect = 2e-19
Identities = 52/134 (38%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQ 418
S P GWG GYV+QKAYLEFF +++ +++E + ++ Y + E + +
Sbjct: 448 STDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY-ITDYEGSLETNGE 506
Query: 417 ADV-NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEV 241
DV +AVTWGVFP E+IQPT+V+ ASF WKDEA+ + SWA + LL +
Sbjct: 507 LDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAY-SLGLSWAKAHSSTSAPFKLLTNI 565
Query: 240 KNSYYLVSLVENDY 199
+ L +V+ND+
Sbjct: 566 VKEWKLCVIVDNDF 579
[156][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 99.4 bits (246), Expect = 2e-19
Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 19/150 (12%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC----KALPSITYMAVNKGEQWVSNTAQ-A 415
GWG GYVYQK YLEF + + + + ++ + S+TY+A + W SN A
Sbjct: 453 GWGPSDGYVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWWSNQPDGA 512
Query: 414 DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAF---ETWSRSWANLYPEAD-------- 268
AVTWGVFP +E++QPTIV+ SF W+DE + + W + + P+ D
Sbjct: 513 KATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRILQDWRDIFVHASPDGDQCDNGSAQ 572
Query: 267 ---PSRNLLEEVKNSYYLVSLVENDYINGD 187
PS L++ + + Y LV+L++ND+++ D
Sbjct: 573 RENPSAKLMQLMIDDYVLVNLIDNDFVSVD 602
[157][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 99.4 bits (246), Expect = 2e-19
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 4/135 (2%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKA---LPSITYMAVN-KGEQWVSNTAQAD 412
GWG G+V+QKA++E F +A+ K + ++++ A N KG+ S+ A
Sbjct: 522 GWGPKNGFVFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGS 581
Query: 411 VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNS 232
NAVTWG FP KEII PTI++ SF W +EAF W WA +Y + +R +++ +K
Sbjct: 582 TNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSETRKVIDGIKED 640
Query: 231 YYLVSLVENDYINGD 187
+LV+++ + Y+ G+
Sbjct: 641 VWLVNVIHHAYVEGE 655
[158][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 99.0 bits (245), Expect = 3e-19
Identities = 59/168 (35%), Positives = 86/168 (51%), Gaps = 23/168 (13%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---------ITYMAVNKG 445
S+ GWG GYVYQK YLEFF K+ + A++ + +TY AV++
Sbjct: 445 SNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQK 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY----- 280
+ SNT D+NAVTWGVFP +EI+QPTIV+ SF WKDE + + W ++
Sbjct: 505 GKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFV 563
Query: 279 -------PEADPSRNLLEEVKNSYYLVSLVENDYI--NGDIFAVFADL 163
+ D L+ + Y L ++V N++I N IF + +L
Sbjct: 564 KDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFIDDNQTIFKLIDEL 611
[159][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 99.0 bits (245), Expect = 3e-19
Identities = 59/168 (35%), Positives = 86/168 (51%), Gaps = 23/168 (13%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPS---------ITYMAVNKG 445
S+ GWG GYVYQK YLEFF K+ + A++ + +TY AV++
Sbjct: 445 SNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQK 504
Query: 444 EQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLY----- 280
+ SNT D+NAVTWGVFP +EI+QPTIV+ SF WKDE + + W ++
Sbjct: 505 GKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSDFV 563
Query: 279 -------PEADPSRNLLEEVKNSYYLVSLVENDYI--NGDIFAVFADL 163
+ D L+ + Y L ++V N++I N IF + +L
Sbjct: 564 KDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFIDDNQTIFKLIDEL 611
[160][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 99.0 bits (245), Expect = 3e-19
Identities = 50/141 (35%), Positives = 79/141 (56%), Gaps = 4/141 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFF---CSKEKLDAVVEKCKALPSITYMAVN-KGEQWVS 430
S GWG G+V+QKA++E F + L A + ++++ A N KG+ S
Sbjct: 516 SSDSIFGWGPKNGFVFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISS 575
Query: 429 NTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLL 250
+ A NAVTWG FP KEII PTI++ SF W +EAF W WA +Y + +R ++
Sbjct: 576 DEAVGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKDSQTRKII 634
Query: 249 EEVKNSYYLVSLVENDYINGD 187
+ +K +LV+++ + Y+ G+
Sbjct: 635 DGIKEDVWLVNVIHHAYVEGE 655
[161][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 98.6 bits (244), Expect = 3e-19
Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 9/158 (5%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKE----KLDAVVEKCKALPSITYMAVNKGEQWVS 430
S GWG G +YQKA++E F K+ KL ++K +ITY + + S
Sbjct: 488 SSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTS 547
Query: 429 NTA-----QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP 265
N NA+TWGVFP+KE++QPTI+D SF W +EAF W WA Y +
Sbjct: 548 NLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSK 606
Query: 264 SRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL*ENQ 151
+ LL + YYLVSL+ +D+ D +A++ L EN+
Sbjct: 607 TYELLNSIYKDYYLVSLISHDF--KDEYALWNILLENK 642
[162][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 98.6 bits (244), Expect = 3e-19
Identities = 53/132 (40%), Positives = 77/132 (58%), Gaps = 5/132 (3%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNT-AQADV-- 409
GWG G VYQKA++E F K+ + + +A SITY A +K + + A D+
Sbjct: 490 GWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKL 549
Query: 408 --NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLEEVKN 235
NAVTWGVFP+KE++QPT++D SF W +E+F W W+ Y + S LL +V
Sbjct: 550 TKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWSRCYKKNSKSFELLNKVYE 608
Query: 234 SYYLVSLVENDY 199
+Y LV L+ +D+
Sbjct: 609 NYVLVCLIYHDF 620
[163][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 97.8 bits (242), Expect = 6e-19
Identities = 55/142 (38%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDA-VVEKCKALPS---ITYMAVNKGEQWVS 430
S GWG G+V+QK+++E F KE+ + K K + ITY A + + S
Sbjct: 490 SSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQS 549
Query: 429 NT-----AQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP 265
N + NAVTWGVFP +E++QPTI+D SF W +EAF W WA Y +
Sbjct: 550 NLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW-LEWARCYKKNSV 608
Query: 264 SRNLLEEVKNSYYLVSLVENDY 199
S NLL + YYLVSL+ +++
Sbjct: 609 SYNLLNSINGDYYLVSLIYHNF 630
[164][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 97.8 bits (242), Expect = 6e-19
Identities = 59/158 (37%), Positives = 83/158 (52%), Gaps = 9/158 (5%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKE----KLDAVVEKCKALPSITYMAVNKGEQWVS 430
S GWG G +YQKA++E F K+ KL ++K +ITY + + S
Sbjct: 488 SSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTS 547
Query: 429 NTA-----QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADP 265
N NA+TWGVFP KE++QPTI+D SF W +EAF W WA Y +
Sbjct: 548 NLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW-LEWARCYKKTSK 606
Query: 264 SRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL*ENQ 151
+ LL + YYLVSL+ +D+ D +A++ L EN+
Sbjct: 607 TYELLNSIYKDYYLVSLISHDF--KDEYALWNILLENK 642
[165][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 97.8 bits (242), Expect = 6e-19
Identities = 54/150 (36%), Positives = 78/150 (52%), Gaps = 17/150 (11%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCS----KEKLDAVVEKCKALPSITYMAVNKGEQWV 433
SD P GWG P G+V+QK ++EFFC K L +++K + + A N +
Sbjct: 512 SDDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQK-HGHEKLAWFATNAAGDFE 570
Query: 432 SNTAQA------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 289
S+ +VNAVTWGVF KEI+ PTI++ SF W DEA+ W W
Sbjct: 571 SSLPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWR 629
Query: 288 NLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP++ + LE+ KN +LV +V D+
Sbjct: 630 RIYPKSSATEKFLEKTKNDVWLVCVVGQDF 659
[166][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 97.8 bits (242), Expect = 6e-19
Identities = 54/157 (34%), Positives = 80/157 (50%), Gaps = 23/157 (14%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSIT-YMAVNKGEQWVSNTA 421
S+ T GWG G+V+QKA++E F + A+ EK + + + A N + S+
Sbjct: 496 SNDRTFGWGPQNGFVFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDG 555
Query: 420 QADV----------------------NAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFET 307
D NAVTWGVFP KEI+ PTI++ SF W +EAF
Sbjct: 556 GGDAPDGAPTGNGFADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGI 615
Query: 306 WSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYI 196
W+ WA +Y + PS LLE ++ +LV+++ +DYI
Sbjct: 616 WA-EWAKVYGKDSPSEKLLESLRADLWLVNIIHHDYI 651
[167][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 97.4 bits (241), Expect = 7e-19
Identities = 46/92 (50%), Positives = 60/92 (65%), Gaps = 1/92 (1%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-SITYMAVNKGEQWVSNTA 421
S P VGWG GYV+QKAYLEFF S+E +A+++ K + Y VN + ++N
Sbjct: 523 SSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAP 582
Query: 420 QADVNAVTWGVFPAKEIIQPTIVDPASFNVWK 325
+ NAVTWG+FP +EIIQPT+VDP SF WK
Sbjct: 583 ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWK 614
[168][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 96.7 bits (239), Expect = 1e-18
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 12/146 (8%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVNKGEQW--- 436
S T GWG G+V+QKA++E F + E+ + ++ + A N +
Sbjct: 515 SRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATS 574
Query: 435 ------VSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPE 274
V A NAVTWGVFP KEII PTI++ SF W +EAF+ W W+ +Y
Sbjct: 575 DDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVYGR 633
Query: 273 ADPSRNLLEEVKNSYYLVSLVENDYI 196
S L+ VK Y+LV+++ +D++
Sbjct: 634 GHESEKFLKTVKEEYWLVNIIHHDFV 659
[169][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 96.7 bits (239), Expect = 1e-18
Identities = 53/161 (32%), Positives = 78/161 (48%), Gaps = 28/161 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVNKGEQWVS 430
+D P GWG G+V+QKA++EFFC+ L +++ + + A N + S
Sbjct: 520 NDHPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFES 579
Query: 429 NTAQAD------------------------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
++ D VNAVTWGVF KEI+ PTI++ SF W D
Sbjct: 580 SSPPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGD 639
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
EAF W W ++P P+ LL+++KN +LV +V Y
Sbjct: 640 EAFRIWD-EWRRVFPRGSPTEKLLDQLKNDVWLVCVVGQKY 679
[170][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVN-KGEQWV 433
SD P GWG P G+V+QK ++EFFC + ++++ + + A N KG+
Sbjct: 516 SDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFES 575
Query: 432 SNTAQA-----------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
S AQ +VN VTWGVF KEI+ PTI++ SF W DEAF W W
Sbjct: 576 SLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRR 634
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP + L ++K+ +LV +V D+
Sbjct: 635 IYPRNSATERFLNDIKDDVWLVCVVGQDF 663
[171][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 96.3 bits (238), Expect = 2e-18
Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 16/149 (10%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVN-KGEQWV 433
SD P GWG P G+V+QK ++EFFC + ++++ + + A N KG+
Sbjct: 564 SDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFES 623
Query: 432 SNTAQA-----------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWAN 286
S AQ +VN VTWGVF KEI+ PTI++ SF W DEAF W W
Sbjct: 624 SLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRR 682
Query: 285 LYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP + L ++K+ +LV +V D+
Sbjct: 683 IYPRNSATERFLNDIKDDVWLVCVVGQDF 711
[172][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 95.5 bits (236), Expect = 3e-18
Identities = 53/137 (38%), Positives = 77/137 (56%), Gaps = 10/137 (7%)
Frame = -3
Query: 579 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP-----SITYMAVN-----KGEQWVS 430
GWG G VYQKA++E F KE+ ++ + K P +ITY + + +V
Sbjct: 489 GWGPKNGIVYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVGDAEGNIESNLFVG 547
Query: 429 NTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLL 250
A NA+TWGVFP+KE++QPTI+D SF W +EAF W WA Y + + LL
Sbjct: 548 PDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWI-EWARCYKKNTKTFQLL 606
Query: 249 EEVKNSYYLVSLVENDY 199
+ ++Y LVSL+ +D+
Sbjct: 607 NSIYSNYVLVSLIHHDF 623
[173][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 94.7 bits (234), Expect = 5e-18
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 28/157 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVNKGEQWVS 430
SD P GWG P G+V+QKA++EFFCSK+ + ++ + A N + S
Sbjct: 522 SDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFES 581
Query: 429 NTAQA------------------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
+T+ + VNAVTWGVF KEII PTI++ SF W +
Sbjct: 582 STSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGE 641
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
EAF W W ++P P+ LL VK +LV ++
Sbjct: 642 EAFRIWD-EWRRIFPRGSPTEKLLNRVKEDTWLVCVI 677
[174][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 94.7 bits (234), Expect = 5e-18
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 28/157 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVNKGEQWVS 430
SD P GWG P G+V+QKA++EFFCSK+ + ++ + A N + S
Sbjct: 522 SDHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFES 581
Query: 429 NTAQA------------------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
+T+ + VNAVTWGVF KEII PTI++ SF W +
Sbjct: 582 STSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGE 641
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
EAF W W ++P P+ LL VK +LV ++
Sbjct: 642 EAFRIWD-EWRRIFPRGSPTEKLLNRVKEDTWLVCVI 677
[175][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 94.7 bits (234), Expect = 5e-18
Identities = 55/151 (36%), Positives = 76/151 (50%), Gaps = 18/151 (11%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVN-KGEQWV 433
+D P GWG G+V+QK ++EFFCS +++ A +T+ A N KG+
Sbjct: 515 NDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFES 574
Query: 432 SNTAQA-------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSW 292
S AQ VNAVTWGVF KEI+ PTI++ SF W +EAF W W
Sbjct: 575 SLPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EW 633
Query: 291 ANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP P+ L+ KN +LV +V +
Sbjct: 634 RRIYPRGSPTETYLDTTKNDSWLVCVVGQQF 664
[176][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 94.4 bits (233), Expect = 6e-18
Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 28/161 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
+D P GWG G+V+QKA++EFFC +++++ + + + A N ++S
Sbjct: 520 NDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMS 579
Query: 429 NTAQAD------------------------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
++ D V AVTWGVF KEI+ PTI++ SF W D
Sbjct: 580 SSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGD 639
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
EAF W W ++P P+ LL+++KN +L+ V Y
Sbjct: 640 EAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679
[177][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 94.4 bits (233), Expect = 6e-18
Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 28/161 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
+D P GWG G+V+QKA++EFFC +++++ + + + A N ++S
Sbjct: 519 NDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMS 578
Query: 429 NTAQAD------------------------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
++ D V AVTWGVF KEI+ PTI++ SF W D
Sbjct: 579 SSPATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGD 638
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
EAF W W ++P P+ LL+++KN +L+ V Y
Sbjct: 639 EAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 678
[178][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 94.4 bits (233), Expect = 6e-18
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 17/150 (11%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVN-KGEQWV 433
SD P GWG P G+V+QK ++EFFC + V++ + + A N KG+
Sbjct: 525 SDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFES 584
Query: 432 S----NTAQAD--------VNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWA 289
S NT D VNAVTWGVF KEI+ PTI++ SF W DEA+ W W
Sbjct: 585 SLPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWR 643
Query: 288 NLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
+YP+ + L++ KN +LV +V ++
Sbjct: 644 RIYPKNSATERFLDDTKNDVWLVCVVGQEF 673
[179][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 94.0 bits (232), Expect = 8e-18
Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 28/161 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
+D P GWG G+V+QKA++EFFC +++++ + + + A N ++S
Sbjct: 520 NDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMS 579
Query: 429 NTAQAD------------------------VNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
++ D V AVTWGVF KEI+ PTI++ SF W D
Sbjct: 580 SSPATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGD 639
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
EAF W W ++P P+ LL+++KN +L+ V Y
Sbjct: 640 EAFRIWD-EWRRIFPRGSPTERLLDQLKNDVWLICCVGQKY 679
[180][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 93.6 bits (231), Expect = 1e-17
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 23/152 (15%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
SD P GWG G+V+QKA++EFFCS + + +++ K +++ A N + S
Sbjct: 524 SDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQS 583
Query: 429 NTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFET 307
+++ VNAVTWGVF KEII PTI++ SF W DEAF
Sbjct: 584 SSSFTGITGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRI 643
Query: 306 WSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
W W ++ P+ LL+++K +L+ +V
Sbjct: 644 WD-EWRRIFRRGSPTEQLLDQLKKDAWLICVV 674
[181][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 90.9 bits (224), Expect = 7e-17
Identities = 50/152 (32%), Positives = 77/152 (50%), Gaps = 23/152 (15%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
SD P GWG G+V+QKA++EFFCS + + +++ K +++ A N + S
Sbjct: 524 SDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQS 583
Query: 429 NTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFET 307
+++ VNAVTWGVF KEII PTI++ SF W EAF
Sbjct: 584 SSSFTGTTGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRI 643
Query: 306 WSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
W W ++ P+ LL+++K +L+ +V
Sbjct: 644 WD-EWRRIFRRGSPTEQLLDQLKKDAWLICVV 674
[182][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 90.9 bits (224), Expect = 7e-17
Identities = 50/152 (32%), Positives = 77/152 (50%), Gaps = 23/152 (15%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVE---KCKALPSITYMAVNKGEQWVS 430
SD P GWG G+V+QKA++EFFCS + + +++ K +++ A N + S
Sbjct: 524 SDHPIFGWGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQS 583
Query: 429 NTA-------------------QADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFET 307
+++ VNAVTWGVF KEII PTI++ SF W EAF
Sbjct: 584 SSSFTGTTGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRI 643
Query: 306 WSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
W W ++ P+ LL+++K +L+ +V
Sbjct: 644 WD-EWRRIFRRGSPTEQLLDQLKKDAWLICVV 674
[183][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 90.9 bits (224), Expect = 7e-17
Identities = 49/138 (35%), Positives = 76/138 (55%), Gaps = 5/138 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQ-----WV 433
S+ GWG G VYQK+++E F + + K + + TY +K + +
Sbjct: 476 SNDNVFGWGPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGRIELSLFT 533
Query: 432 SNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNL 253
+ + + NAVTWGVFP KE++QPT++D SF W +EAF W WA Y + + L
Sbjct: 534 NESTRHLKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKTYEL 592
Query: 252 LEEVKNSYYLVSLVENDY 199
L V+++Y LVSL+ ++Y
Sbjct: 593 LNSVRDNYVLVSLIHHEY 610
[184][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITYMAVNKGEQWVSN 427
S GWG G +YQKA++E F +++ + ++ +Y A + + +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ VTWGVFP + Q TI++ SF W+DEAF WS WA L+P P+ LL
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627
Query: 246 EVKNSYYLVSLVENDYINGD 187
V Y LVS+V +D+ D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647
[185][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITYMAVNKGEQWVSN 427
S GWG G +YQKA++E F +++ + ++ +Y A + + +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ VTWGVFP + Q TI++ SF W+DEAF WS WA L+P P+ LL
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627
Query: 246 EVKNSYYLVSLVENDYINGD 187
V Y LVS+V +D+ D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647
[186][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITYMAVNKGEQWVSN 427
S GWG G +YQKA++E F +++ + ++ +Y A + + +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ VTWGVFP + Q TI++ SF W+DEAF WS WA L+P P+ LL
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627
Query: 246 EVKNSYYLVSLVENDYINGD 187
V Y LVS+V +D+ D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647
[187][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCK---ALPSITYMAVNKGEQWVSN 427
S GWG G +YQKA++E F +++ + ++ +Y A + + +N
Sbjct: 509 SSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETN 568
Query: 426 TAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLLE 247
+ VTWGVFP + Q TI++ SF W+DEAF WS WA L+P P+ LL
Sbjct: 569 LDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPANILLR 627
Query: 246 EVKNSYYLVSLVENDYINGD 187
V Y LVS+V +D+ D
Sbjct: 628 LVHKDYCLVSIVHHDFKETD 647
[188][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 88.6 bits (218), Expect = 3e-16
Identities = 55/158 (34%), Positives = 84/158 (53%), Gaps = 5/158 (3%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKAL-PSITYMAVN--KGEQWVSN 427
S P VGWG GYV+QKAYLEFF S E + A+++ K P + Y VN K Q +
Sbjct: 487 STDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHKHTQLLKL 546
Query: 426 TAQADVNAVTWGVFPAKEIIQPT-IVDPASFNVWKDEAFETWSRSWANLYPEADPSRNLL 250
+ +D G+ P + Q + ++ DEAF W WA LY E PSR ++
Sbjct: 547 LSSSDT-----GMGPVIQNAQDLGNLSVIWISITDDEAFALWIEQWAKLYEEESPSRMII 601
Query: 249 EEVKNSYYLVSLVENDY-INGDIFAVFADL*ENQETTT 139
+ + ++YYLV+LV+ND+ + ++ V D + ++ T
Sbjct: 602 QYIHDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDSPT 639
[189][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 86.7 bits (213), Expect = 1e-15
Identities = 51/157 (32%), Positives = 72/157 (45%), Gaps = 28/157 (17%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL---PSITYMAVNKGEQWVS 430
SD T GWG P G+V+QKA++EFFCS + ++ + A N + +
Sbjct: 520 SDDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFEA 579
Query: 429 NTAQA------------------------DVNAVTWGVFPAKEIIQPTIVDPASFNVWKD 322
+T + VNAVTWGVF KEII PTI++ SF W +
Sbjct: 580 STPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGE 639
Query: 321 EAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
EAF W W ++ P+ LL + K +LV +V
Sbjct: 640 EAFRIWD-EWRRIFARGSPTEKLLAQTKEDVWLVCVV 675
[190][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 86.7 bits (213), Expect = 1e-15
Identities = 54/169 (31%), Positives = 74/169 (43%), Gaps = 31/169 (18%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVN------- 451
SD P GWG P G+V+QKA++EFFC V+ ++ A+N
Sbjct: 525 SDHPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLES 584
Query: 450 ----------KGEQWVSNTAQADVN----------AVTWGVFPAKEIIQPTIVDPASFNV 331
K E S A AD AVTWG F +EI PTI++ SF
Sbjct: 585 SFLISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRA 644
Query: 330 WKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDI 184
W +EAF W W +YP + LL E KN +L+ ++ + Y G +
Sbjct: 645 WGEEAFRIWD-EWRRIYPRGSATERLLNETKNDVWLLCVIGHRYGAGTV 692
[191][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 84.7 bits (208), Expect = 5e-15
Identities = 52/161 (32%), Positives = 75/161 (46%), Gaps = 32/161 (19%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKCKAL------PSITYMAVNKGEQ 439
+D P GWG G+V+QKA++EFFC + + K K L + A+N
Sbjct: 481 NDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHS---KLKPLLNSYGHDEFAWFAMNAKGD 537
Query: 438 WVSNTA-------------------------QADVNAVTWGVFPAKEIIQPTIVDPASFN 334
+ S+T+ VNAVTWGVF KEI+ PTI++ SF
Sbjct: 538 FQSSTSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFR 597
Query: 333 VWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLV 211
W +EAF W W ++P S L+ +VK+ +LV +V
Sbjct: 598 AWGEEAFGIW-EEWRRIFPRGSASEKLIRDVKDDVWLVCVV 637
[192][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 83.2 bits (204), Expect = 1e-14
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 31/164 (18%)
Frame = -3
Query: 597 SDSPTVGWGGP-VGYVYQKAYLEFFCSKEKLDAVVEKC---KALPSITYMAVN------- 451
SD P GWG P G+V+QKA++EFFC V+ ++ A+N
Sbjct: 523 SDHPVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEFSWFAINATGHLES 582
Query: 450 ----------KGEQWVSNTAQADVN----------AVTWGVFPAKEIIQPTIVDPASFNV 331
K E S+T AD AVTWG F +EI PTI++ SF
Sbjct: 583 SFLLSASSSPKPED-ASSTIAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRA 641
Query: 330 WKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDY 199
W +EAF W W +YP + LL E KN +L+ ++ + Y
Sbjct: 642 WGEEAFRIWD-EWRRIYPRGSATERLLNETKNDAWLLCVIGHRY 684
[193][TOP]
>UniRef100_A7QB32 Chromosome chr5 scaffold_72, whole genome shotgun sequence n=1
Tax=Vitis vinifera RepID=A7QB32_VITVI
Length = 170
Score = 57.4 bits (137), Expect = 9e-07
Identities = 26/34 (76%), Positives = 32/34 (94%)
Frame = -3
Query: 267 PSRNLLEEVKNSYYLVSLVENDYINGDIFAVFAD 166
PSR LLEEV++SY+LVSLV+NDYI+GD+FAVF D
Sbjct: 110 PSRILLEEVQSSYFLVSLVDNDYIHGDLFAVFTD 143
[194][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 56.2 bits (134), Expect = 2e-06
Identities = 24/49 (48%), Positives = 32/49 (65%)
Frame = -3
Query: 597 SDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVN 451
S P +GWGG GY+YQKAYLEFF S E + ++++ K P + Y VN
Sbjct: 44 STDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQVNYHVVN 92