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[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 347 bits (891), Expect = 2e-94
Identities = 166/166 (100%), Positives = 166/166 (100%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI
Sbjct: 206 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 265
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV
Sbjct: 266 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 325
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS
Sbjct: 326 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 371
[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 347 bits (891), Expect = 2e-94
Identities = 166/166 (100%), Positives = 166/166 (100%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI
Sbjct: 396 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS
Sbjct: 516 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 561
[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 306 bits (783), Expect = 6e-82
Identities = 142/166 (85%), Positives = 152/166 (91%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFKELC+GNLKSSPWSELDGLQPET+IINEQL K+NS GFLTINSQPSVNA +SDSP +
Sbjct: 396 EKFKELCLGNLKSSPWSELDGLQPETRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGP GYVYQKAYLEFFCSK+KLD +VEK KA PSITYMAVNK E WVSNT ++DVNAV
Sbjct: 456 GWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPAKE+IQPTIVDPASF VWKDEAFE WSRSWANLYPE DPS
Sbjct: 516 TWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRSWANLYPEADPS 561
[4][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 290 bits (742), Expect = 4e-77
Identities = 131/166 (78%), Positives = 148/166 (89%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFK C+G LKSSPWSEL+GLQPETKIINEQLG+IN GFLTINSQP+VNA KSDSP++
Sbjct: 410 EKFKVYCLGKLKSSPWSELEGLQPETKIINEQLGRINLKGFLTINSQPAVNAEKSDSPSV 469
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSK+KL+ LVE+ KAFP +TYMAVN+ +W+SN +DVNAV
Sbjct: 470 GWGGPGGYVYQKAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALTDVNAV 529
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPAKE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPS
Sbjct: 530 TWGVFPAKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPS 575
[5][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 290 bits (741), Expect = 5e-77
Identities = 131/166 (78%), Positives = 146/166 (87%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFK C+G LKSSPWSELDGLQPETKIINEQLGKIN GFLTINSQP+VN KSDSP++
Sbjct: 407 EKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSV 466
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK +W+SN +DVNAV
Sbjct: 467 GWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAV 526
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPS
Sbjct: 527 TWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPS 572
[6][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 290 bits (741), Expect = 5e-77
Identities = 131/166 (78%), Positives = 146/166 (87%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFK C+G LKSSPWSELDGLQPETKIINEQLGKIN GFLTINSQP+VN KSDSP++
Sbjct: 26 EKFKVYCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSV 85
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSKDKL+ LV+K K+FP +TY+AVNK +W+SN +DVNAV
Sbjct: 86 GWGGPGGYVYQKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAV 145
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE+IQPT+VDP SF VWKDEAFEIWSR WA+LYPE DPS
Sbjct: 146 TWGVFPGKEIIQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPS 191
[7][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 283 bits (723), Expect = 6e-75
Identities = 127/166 (76%), Positives = 145/166 (87%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKFK+ C+G LK+SPWSELDGLQPETKIINEQLGKIN GFLTINSQP+VN KSDSP++
Sbjct: 411 EKFKKHCLGKLKTSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSV 470
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAY+EFFCS DKL L+EK KA P +TYMAVN+ +SN G++DVNAV
Sbjct: 471 GWGGPGGYVYQKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQNDVNAV 530
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP K++IQPT+VDPASF VWKDEAFEIW+R WA+LYPE DPS
Sbjct: 531 TWGVFPGKQIIQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPS 576
[8][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 278 bits (712), Expect = 1e-73
Identities = 126/166 (75%), Positives = 144/166 (86%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F + C+G LKSSPWSELDGLQPE+KIINE LG INS GFLTINSQP+VN KSDS ++
Sbjct: 396 ERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDSLSV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K PS+TYMAVNK W+SN G +VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHPSLTYMAVNKEGTWMSNVGPGEVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPS
Sbjct: 516 TWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPS 561
[9][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 275 bits (704), Expect = 9e-73
Identities = 125/166 (75%), Positives = 143/166 (86%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F + C+G LKSSPWSELDGLQPE+KIINE LG INS GFLTINSQP+VN KSDS ++
Sbjct: 396 ERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDSLSV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+SN G +VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPS
Sbjct: 516 TWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPS 561
[10][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 275 bits (704), Expect = 9e-73
Identities = 125/166 (75%), Positives = 143/166 (86%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F + C+G LKSSPWSELDGLQPE+KIINE LG INS GFLTINSQP+VN KSDS ++
Sbjct: 389 ERFIKFCLGKLKSSPWSELDGLQPESKIINELLGNINSKGFLTINSQPAVNGEKSDSLSV 448
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCS++KL+ LV+K K S+TYMAVNK W+SN G +VNAV
Sbjct: 449 GWGGPGGYVYQKAYLEFFCSREKLNALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAV 508
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPA+E+IQPT+VDP+SF VWKDEAFEIWSR WA LYPEDDPS
Sbjct: 509 TWGVFPAREIIQPTVVDPSSFMVWKDEAFEIWSRGWALLYPEDDPS 554
[11][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 263 bits (672), Expect = 5e-69
Identities = 122/166 (73%), Positives = 137/166 (82%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G L SSPWSELDGLQPETKII++QL KIN GFLTINSQP+VN KSDSP +
Sbjct: 396 ERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK SN + VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGESFSNIAPNAVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE+IQPT+VDPASF VWKDEAFEIW+R WA L+PE D S
Sbjct: 516 TWGVFPGKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEGDSS 561
[12][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 262 bits (669), Expect = 1e-68
Identities = 122/166 (73%), Positives = 140/166 (84%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G LKSSPWSELDGLQPET II++QL KINS GFLTINSQP+VNA KS+SP++
Sbjct: 384 ERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVNAEKSESPSV 443
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAY+EFFC+K+KL L+EKSKAFPS+TY+AVNK +SN + VNAV
Sbjct: 444 GWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAV 503
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE+IQPT+VD ASF VWKDEAFEIWSR WA L+PE D S
Sbjct: 504 TWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSS 549
[13][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 258 bits (660), Expect = 1e-67
Identities = 120/166 (72%), Positives = 137/166 (82%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G L SSPWSELDGLQPETKII++QL KIN GFLTINSQP+VN +SDS ++
Sbjct: 396 ERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D S
Sbjct: 516 TWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSS 561
[14][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 258 bits (660), Expect = 1e-67
Identities = 120/166 (72%), Positives = 137/166 (82%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G L SSPWSELDGLQPETKII++QL KIN GFLTINSQP+VN +SDS ++
Sbjct: 39 ERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSV 98
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAV
Sbjct: 99 GWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAV 158
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D S
Sbjct: 159 TWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSS 204
[15][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 258 bits (660), Expect = 1e-67
Identities = 120/166 (72%), Positives = 137/166 (82%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G L SSPWSELDGLQPETKII++QL KIN GFLTINSQP+VN +SDS ++
Sbjct: 396 ERFMNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFCSK+KLD L+EKSKAFPS+TY+AVNK SN + VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE++QPT+VD ASF VWKDEAFEIWS+ WA L+PE D S
Sbjct: 516 TWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKGWACLFPEGDSS 561
[16][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 256 bits (653), Expect = 7e-67
Identities = 118/166 (71%), Positives = 134/166 (80%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E+F C G L SSPWSELDGLQPETKII++QL IN GFLTINSQP+VN KSDSP +
Sbjct: 396 ERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVNGEKSDSPTV 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGGPGGYVYQKAYLEFFC+K+KLD L+EK KAFPS+TY+AVNK SN + VNAV
Sbjct: 456 GWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE+IQPT+VD ASF VWKDEAFEIW+R W ++PE D S
Sbjct: 516 TWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSS 561
[17][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 252 bits (644), Expect = 8e-66
Identities = 115/166 (69%), Positives = 135/166 (81%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
EKF C+G LKS+PWSELDGLQPET INE+L ++N GFLTINSQP+VN KSDSP+I
Sbjct: 396 EKFANFCVGKLKSNPWSELDGLQPETVKINEKLEQLNRKGFLTINSQPAVNGEKSDSPSI 455
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWGG GYVYQKAY+EFFCS +KL+ LVEK+K P +TY+AVNK +N G +DVNAV
Sbjct: 456 GWGGAAGYVYQKAYVEFFCSPEKLNELVEKAKNLPFVTYIAVNKKGATAANIGPTDVNAV 515
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFPAKEVIQPT+VDP SF VWKDEAF+ W + WA+LYP+ DPS
Sbjct: 516 TWGVFPAKEVIQPTVVDPVSFMVWKDEAFQAWEQEWASLYPDGDPS 561
[18][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 243 bits (620), Expect = 5e-63
Identities = 110/164 (67%), Positives = 130/164 (79%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + C G L + PWSEL+GLQPET INE+L +N GFLTINSQP+VN KSDSP++GW
Sbjct: 398 FAKYCQGTLSTHPWSELEGLQPETVQINEKLVALNQGGFLTINSQPAVNGEKSDSPSVGW 457
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
GGPGGYVYQKAY+EFFCS +KL ++EK+K PS+TY+AVN SN G + VNAVTW
Sbjct: 458 GGPGGYVYQKAYVEFFCSPEKLQAVIEKAKTSPSLTYIAVNAKGETKSNVGPTSVNAVTW 517
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFPAKEVIQPT+VDP SF VWKDEAF+ W + WA+LYPEDD S
Sbjct: 518 GVFPAKEVIQPTVVDPVSFMVWKDEAFQAWDQEWASLYPEDDAS 561
[19][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 234 bits (596), Expect = 3e-60
Identities = 106/164 (64%), Positives = 129/164 (78%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + C G L + PWSEL+GLQPET IN++L +N+ GFLTINSQP+VN KSDSP++GW
Sbjct: 398 FAKYCQGTLSTHPWSELEGLQPETSQINDKLVALNTQGFLTINSQPAVNGEKSDSPSVGW 457
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
GGPGGYVYQKAY+EFFCS +KL ++EK+K+ PS+T++AVN SN G + VNAVTW
Sbjct: 458 GGPGGYVYQKAYVEFFCSPEKLQAVIEKAKSNPSLTFIAVNAKGETQSNIGPNCVNAVTW 517
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFPAKEVIQPT+VDP SF VWKDEAF+ W WA LY E+D S
Sbjct: 518 GVFPAKEVIQPTVVDPVSFMVWKDEAFQTWDHEWAALYSEEDSS 561
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 178 bits (452), Expect = 2e-43
Identities = 88/155 (56%), Positives = 101/155 (65%), Gaps = 1/155 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDG-LQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGG 300
G + PW+ELDG L E I E L +N+NG+LTINSQP VN SD GWGGPGG
Sbjct: 404 GEVSLLPWAELDGGLTAEAAAIREPLAALNANGYLTINSQPRVNGVASDDAVHGWGGPGG 463
Query: 299 YVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPA 120
YVY KAY+EFFCS + TL K A PSITY+A + + N VNAVTWGVFP
Sbjct: 464 YVYGKAYVEFFCSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVFPG 523
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPE 15
KEVIQPT+V SF VWKDEAFE+W+ W LY E
Sbjct: 524 KEVIQPTVVCAPSFAVWKDEAFELWTSEWGALYEE 558
[21][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 177 bits (450), Expect = 3e-43
Identities = 91/167 (54%), Positives = 109/167 (65%), Gaps = 3/167 (1%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQP---ETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPA 324
F C G+L PWS QP ET +I EQL K+N G+LTINSQP+V+ +SD
Sbjct: 394 FARFCRGDLAKLPWST----QPPASETSLIIEQLAKMNELGYLTINSQPAVDGVRSDDKV 449
Query: 323 IGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNA 144
GWG PGGYVYQKAYLEFF S D L L+ + + P ITY AVNK + +NT NA
Sbjct: 450 HGWGPPGGYVYQKAYLEFFVSPDLLSPLIRRIEKDPRITYYAVNKQGDLRTNTHSESPNA 509
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VTWGVFP KE++QPTIV+ SF WKDEAFE+ WA+LYP + PS
Sbjct: 510 VTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GLQWAHLYPAESPS 555
[22][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 176 bits (445), Expect = 1e-42
Identities = 87/153 (56%), Positives = 103/153 (67%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWS D L ET I + L INS G LTINSQP+VNA S GWGGP GYVYQKAY
Sbjct: 438 PWSN-DALALETLFIKKSLEYINSKGILTINSQPNVNALPSTHEVFGWGGPNGYVYQKAY 496
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S ++ TL+E FP I Y A++ SE+ VSN+ AVTWGVFP +E++QP
Sbjct: 497 LEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIAVTWGVFPGREILQP 556
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W+ WANLYPE+ S
Sbjct: 557 TVVDPTSFSYWKDEAFALWTNQWANLYPEESKS 589
[23][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 175 bits (444), Expect = 1e-42
Identities = 87/164 (53%), Positives = 111/164 (67%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F++ C G +K+ PWSE + ET +I+++L K+N GFLTINSQP+V+ A+SD GW
Sbjct: 406 FQQFCAGQVKALPWSETP-VARETSVISDKLAKMNQLGFLTINSQPAVDGARSDDKVHGW 464
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYVYQKAYLEFF S + LD L+ + +A P ITY AVN + +NT NAVTW
Sbjct: 465 GPKNGYVYQKAYLEFFVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTW 524
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFP E+IQPTIV+ SF WKDEA+EI R+WA +Y PS
Sbjct: 525 GVFPHCEIIQPTIVESISFLAWKDEAYEI-GRNWAKVYEPTSPS 567
[24][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 174 bits (441), Expect = 3e-42
Identities = 80/157 (50%), Positives = 107/157 (68%), Gaps = 1/157 (0%)
Frame = -1
Query: 470 LKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVY 291
++ PW++ D L ET IN++L +INS G LTINSQP+VNAA S P +GWG PGGYV+
Sbjct: 439 VRKIPWND-DDLAAETSFINDKLARINSRGVLTINSQPNVNAAPSTDPVVGWGTPGGYVF 497
Query: 290 QKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVN-KSENWVSNTGESDVNAVTWGVFPAKE 114
QKAYLEFF S++ + L + +P++ Y + + ++ +N + AVTWGVFP KE
Sbjct: 498 QKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNCDQQQPIAVTWGVFPGKE 557
Query: 113 VIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+IQPT+VDP SFK WKDEAF +W+ W LY ED S
Sbjct: 558 IIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKS 594
[25][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 174 bits (441), Expect = 3e-42
Identities = 81/155 (52%), Positives = 106/155 (68%), Gaps = 1/155 (0%)
Frame = -1
Query: 464 SSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQK 285
S PW++ + L ET I E+L NSNG L+INSQPSVNAA S P +GWGG GGY+YQK
Sbjct: 397 SLPWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQK 455
Query: 284 AYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEVI 108
AYLEFF S + + L+++ K +P + Y VN + ++N AVTWGVFP +E++
Sbjct: 456 AYLEFFASPEVVYILLQELKNYPQVNYHVVNNHDTVDITNCDSQTPVAVTWGVFPGREIV 515
Query: 107 QPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SFK+WKDEAF +W + W+ LY ED S
Sbjct: 516 QPTVVDPISFKIWKDEAFSLWEQQWSRLYTEDSKS 550
[26][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 167 bits (424), Expect = 3e-40
Identities = 84/164 (51%), Positives = 105/164 (64%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F C L + PWS+ Q ET +I EQL +N GFLTINSQP+VN+A+SD P GW
Sbjct: 390 FSRFCTKKLSALPWSDQAPSQ-ETSVIAEQLATMNEFGFLTINSQPAVNSARSDDPVFGW 448
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYVYQKAYLEFF + L+ L+ + +ITY +NK + +NT NAVTW
Sbjct: 449 GPSNGYVYQKAYLEFFVNPTLLNLLLTHIERDSNITYYVINKRGDLRTNTHSDGPNAVTW 508
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFP KE++QPTIV+ SF WKDEAFE+ + WA LY + PS
Sbjct: 509 GVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQWAKLYEANSPS 551
[27][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 167 bits (424), Expect = 3e-40
Identities = 85/164 (51%), Positives = 102/164 (62%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F C G L PWS+ L ET +INE L +N GF TINSQP+V+ A+SD P GW
Sbjct: 315 FARFCTGELACLPWSDAP-LAKETSVINEPLRALNERGFFTINSQPAVDGARSDDPVHGW 373
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYVYQKAYLEFF S +LD L+ + A P ITY AVN + +NT NAVTW
Sbjct: 374 GPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMRTNTTSDAPNAVTW 433
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G FP E++QPTIV+ SF WKDEA+EI R WA Y + P+
Sbjct: 434 GCFPHCEILQPTIVESMSFLAWKDEAYEI-GRRWAAFYEPESPT 476
[28][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 167 bits (423), Expect = 3e-40
Identities = 76/153 (49%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L PET ++ +L K+N G LTINSQP+VN S P +GWG GYV+QKAY
Sbjct: 448 PWND-DPLAPETNLLKNELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAY 506
Query: 278 LEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + P + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 507 LEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPNAVTWGIFPGREIIQP 566
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY E+ PS
Sbjct: 567 TVVDPVSFVYWKDEAFALWIEQWAKLYEEESPS 599
[29][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 167 bits (422), Expect = 5e-40
Identities = 74/153 (48%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L PET ++ ++L K+N G LTINSQP++N S +GWG GGYV+QKAY
Sbjct: 454 PWND-DPLAPETNLLKDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAY 512
Query: 278 LEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + P + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 513 LEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQP 572
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY ++ PS
Sbjct: 573 TVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS 605
[30][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 166 bits (420), Expect = 8e-40
Identities = 85/164 (51%), Positives = 104/164 (63%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + C G L + PWS+ ET II QL K+N GFLTINSQP+VN A+SD GW
Sbjct: 350 FAKFCKGELDALPWSD-SAPSKETSIIATQLAKMNELGFLTINSQPAVNGARSDDKIFGW 408
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYVYQKAYLEFF L L++ + +ITY +NK + +NT NAVTW
Sbjct: 409 GPSNGYVYQKAYLEFFVDPALLQLLLKHLERDTNITYHVINKRGDLQTNTHSEGPNAVTW 468
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFP KE+IQPTIV+ SF WKDEA+E+ ++ WA LY D PS
Sbjct: 469 GVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ-WARLYEHDSPS 511
[31][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 165 bits (418), Expect = 1e-39
Identities = 75/153 (49%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L PET ++ +L K+N G LTINSQP+VN S P +GWG GYV+QKAY
Sbjct: 448 PWND-DPLAPETNLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAY 506
Query: 278 LEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + P + Y VN ++N + +AVTWG+FP +E+IQP
Sbjct: 507 LEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQP 566
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY E+ PS
Sbjct: 567 TVVDPVSFMYWKDEAFALWIEQWAKLYEEESPS 599
[32][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 165 bits (417), Expect = 2e-39
Identities = 78/156 (50%), Positives = 106/156 (67%), Gaps = 4/156 (2%)
Frame = -1
Query: 458 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 447 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 506
Query: 281 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEV 111
YLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTWGVFP E+
Sbjct: 507 YLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEI 566
Query: 110 IQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SF+ W+DEA+++W W + YP++ S
Sbjct: 567 AQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKS 602
[33][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 165 bits (417), Expect = 2e-39
Identities = 78/156 (50%), Positives = 106/156 (67%), Gaps = 4/156 (2%)
Frame = -1
Query: 458 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 468 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 527
Query: 281 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEV 111
YLE F + + D L++ + FP + Y A+NK + +N+ E+ AVTWGVFP E+
Sbjct: 528 YLECFMTAELSDKLIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEI 587
Query: 110 IQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SF+ W+DEA+++W W + YP++ S
Sbjct: 588 AQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKS 623
[34][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 164 bits (414), Expect = 4e-39
Identities = 76/164 (46%), Positives = 105/164 (64%), Gaps = 1/164 (0%)
Frame = -1
Query: 491 KELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWG 312
K LC+ PW++ + L PET ++ ++L K+N G LTINSQP++N S P +GWG
Sbjct: 453 KVLCL------PWND-EPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWG 505
Query: 311 GPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTW 135
GGYVYQKAYLEFF S + + L++ K + P + Y VN ++N + NAVTW
Sbjct: 506 PAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTW 565
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G+F +E++QPT+VDP SF WKDEAF +W WA LY ++ PS
Sbjct: 566 GIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPS 609
[35][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 164 bits (414), Expect = 4e-39
Identities = 76/164 (46%), Positives = 105/164 (64%), Gaps = 1/164 (0%)
Frame = -1
Query: 491 KELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWG 312
K LC+ PW++ + L PET ++ ++L K+N G LTINSQP++N S P +GWG
Sbjct: 453 KVLCL------PWND-EPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWG 505
Query: 311 GPGGYVYQKAYLEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENWVSNTGESDVNAVTW 135
GGYVYQKAYLEFF S + + L++ K + P + Y VN ++N + NAVTW
Sbjct: 506 PAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTW 565
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G+F +E++QPT+VDP SF WKDEAF +W WA LY ++ PS
Sbjct: 566 GIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPS 609
[36][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 163 bits (412), Expect = 7e-39
Identities = 74/153 (48%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L K+N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 448 PWND-EPLAAETSLMKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAY 506
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + ++ L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 507 LEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQP 566
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 567 TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS 599
[37][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 163 bits (412), Expect = 7e-39
Identities = 81/164 (49%), Positives = 101/164 (61%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F C GN+K PW++ L E++ I EQL +N NGFLTINSQP++N S GW
Sbjct: 407 FASYCSGNIKRLPWND-SPLSLESENIKEQLVFLNKNGFLTINSQPAINGLPSTDKQHGW 465
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
GG G VY+KAY+EFF S + L+E K P ITY AVN+ + S T NAVTW
Sbjct: 466 GGKNGIVYKKAYIEFFASPENTLKLIEYFKKCPMITYHAVNRKGD--SKTNTKGTNAVTW 523
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G+FP KE+IQPT+VD SF VWKDEAF +W W++ Y S
Sbjct: 524 GIFPGKEIIQPTVVDHNSFMVWKDEAFALWETQWSSTYSPSSTS 567
[38][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 162 bits (411), Expect = 9e-39
Identities = 75/153 (49%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L ET ++ +QL K+N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 456 PWND-DPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAY 514
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 515 LEFFTSSEIVTALLKVLKKYELRVNYHIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQP 574
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY E+ PS
Sbjct: 575 TVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS 607
[39][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 162 bits (411), Expect = 9e-39
Identities = 76/153 (49%), Positives = 99/153 (64%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L ET ++ EQL K+N G LTINSQP++N S P GWG GGYV+QKAY
Sbjct: 313 PWND-DPLATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAY 371
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 372 LEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQP 431
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY E+ PS
Sbjct: 432 TVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS 464
[40][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 162 bits (411), Expect = 9e-39
Identities = 76/153 (49%), Positives = 99/153 (64%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L ET ++ EQL K+N G LTINSQP++N S P GWG GGYV+QKAY
Sbjct: 445 PWND-DPLATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAY 503
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 504 LEFFTSNEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQP 563
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W WA LY E+ PS
Sbjct: 564 TVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS 596
[41][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 162 bits (410), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 477 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 535
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 536 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 595
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 596 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 628
[42][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 162 bits (410), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 495 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 553
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 554 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 613
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 614 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 646
[43][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 162 bits (410), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 454 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 512
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 513 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 572
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 573 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 605
[44][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 162 bits (409), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 477 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 535
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 536 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 595
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 596 TVVDPVSFMFWKDEAFALWIERWGKLYEEESPS 628
[45][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 162 bits (409), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 495 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 553
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 554 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 613
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 614 TVVDPVSFMFWKDEAFALWIERWGKLYEEESPS 646
[46][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 162 bits (409), Expect = 1e-38
Identities = 73/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 454 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 512
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 513 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 572
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 573 TVVDPVSFMFWKDEAFALWIERWGKLYEEESPS 605
[47][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 161 bits (408), Expect = 2e-38
Identities = 73/153 (47%), Positives = 102/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAY
Sbjct: 494 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAY 552
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 553 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 612
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 613 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 645
[48][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 161 bits (408), Expect = 2e-38
Identities = 73/153 (47%), Positives = 102/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAY
Sbjct: 494 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAY 552
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 553 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 612
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 613 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 645
[49][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 161 bits (408), Expect = 2e-38
Identities = 73/153 (47%), Positives = 102/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAY
Sbjct: 453 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAY 511
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 512 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 571
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 572 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 604
[50][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 161 bits (407), Expect = 2e-38
Identities = 80/159 (50%), Positives = 100/159 (62%), Gaps = 1/159 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW E LQPE+ +I +L +N GFLTINSQPSVNAA S + GWGGPGGY
Sbjct: 435 GKIPHIPWCEAT-LQPESFLIQTKLAALNRAGFLTINSQPSVNAALSTHESFGWGGPGGY 493
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVFPA 120
+YQKAY E FCS + + LV K S+ AVN + N + E V A+TWGVFP
Sbjct: 494 IYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTELGGVTALTWGVFPN 553
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+E++QPTI DP F VW +EAF +W+ W+NLY D S
Sbjct: 554 REILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDS 592
[51][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 160 bits (406), Expect = 3e-38
Identities = 73/153 (47%), Positives = 99/153 (64%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L K+N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 451 PWND-EPLAAETSLLKEELQKVNRRGILTINSQPNINGKPSADPVVGWGPSGGYVFQKAY 509
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S + + L++ K + + Y VN ++N + NAVTWG+FP +E+IQP
Sbjct: 510 LEFFTSSETVAALLKVLKKYELRVNYHIVNVKGENITNAPDMQPNAVTWGIFPGREIIQP 569
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 570 TVVDPVSFMSWKDEAFALWIEQWGKLYEEESPS 602
[52][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 160 bits (406), Expect = 3e-38
Identities = 75/156 (48%), Positives = 107/156 (68%), Gaps = 4/156 (2%)
Frame = -1
Query: 458 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 469 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 528
Query: 281 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKEV 111
YLE F + + + L++ + +P + Y A++K ++ +N+ E+ AVTWGVFP E+
Sbjct: 529 YLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPIAVTWGVFPGSEI 588
Query: 110 IQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SF+ W+DEA+++W W + YP++ S
Sbjct: 589 AQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKS 624
[53][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 160 bits (406), Expect = 3e-38
Identities = 72/153 (47%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 453 PWND-EPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 511
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 512 LEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 571
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 572 TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS 604
[54][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 160 bits (406), Expect = 3e-38
Identities = 72/153 (47%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 453 PWND-EPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 511
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 512 LEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 571
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 572 TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS 604
[55][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 160 bits (405), Expect = 4e-38
Identities = 72/153 (47%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 453 PWND-EPLAAETSLMKEELLRVNRQGVLTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 511
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 512 LEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 571
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 572 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 604
[56][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 160 bits (404), Expect = 6e-38
Identities = 78/151 (51%), Positives = 100/151 (66%), Gaps = 1/151 (0%)
Frame = -1
Query: 470 LKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVY 291
+KS P ++ D LQPET ++++QL +IN +GFLT NSQP+VNAA S GWGG GGY+Y
Sbjct: 428 VKSLPLND-DELQPETSLLSDQLYRINGHGFLTTNSQPAVNAALSTDERFGWGGAGGYIY 486
Query: 290 QKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENW-VSNTGESDVNAVTWGVFPAKE 114
QKAYLEFF K +D L+E P + Y ++ + +N AVTWGVFP KE
Sbjct: 487 QKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVTWGVFPGKE 546
Query: 113 VIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
+IQPT+VDP SF WKDEAF +W W +LY
Sbjct: 547 IIQPTVVDPISFNFWKDEAFSLWIEKWQSLY 577
[57][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 159 bits (403), Expect = 7e-38
Identities = 71/153 (46%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 459 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 517
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E++QP
Sbjct: 518 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQP 577
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 578 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 610
[58][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 159 bits (403), Expect = 7e-38
Identities = 72/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 579 PWND-EPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 637
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 638 LEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 697
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 698 TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS 730
[59][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 159 bits (403), Expect = 7e-38
Identities = 71/153 (46%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 494 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY 552
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E++QP
Sbjct: 553 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQP 612
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 613 TVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 645
[60][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 159 bits (403), Expect = 7e-38
Identities = 72/153 (47%), Positives = 100/153 (65%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 495 PWND-EPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 553
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 554 LEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 613
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 614 TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS 646
[61][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 159 bits (403), Expect = 7e-38
Identities = 73/153 (47%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++NA S P +GWG GGYV+QKAY
Sbjct: 494 PWND-EPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAY 552
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ ++ L++ K + + Y V+ ++N E NAVTWG+FP +E+IQP
Sbjct: 553 LEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQP 612
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP SF WKDEAF W W LY E+ PS
Sbjct: 613 TVVDPISFMFWKDEAFAPWIEQWGKLYEEESPS 645
[62][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 158 bits (400), Expect = 2e-37
Identities = 75/166 (45%), Positives = 108/166 (65%), Gaps = 14/166 (8%)
Frame = -1
Query: 458 PWSELD-GLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
PW+E + G+QPET +I+EQL N NG LT+NSQPSVN A S P +GWG PGGY YQKA
Sbjct: 519 PWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKA 578
Query: 281 YLEFFCSKDKLDTLVE-KSKAFP-SITYMAVNKSENWV-----------SNTGESDVNAV 141
YLE F + + + L++ + +P + Y A++K +++ +N+ E+ AV
Sbjct: 579 YLECFMTAELSEKLIDIIEREYPVRVNYHAIDKDVSYILNSHDSMQIFRTNSEETTPIAV 638
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP E+ QPT+VDP SF+ W+DEA+++W W + YP++ S
Sbjct: 639 TWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKS 684
[63][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 155 bits (392), Expect = 1e-36
Identities = 77/155 (49%), Positives = 98/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 461 SPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
+PW++ DGL PET +++ L + N G LTINSQP+VNA S P GWG GGY+ QKA
Sbjct: 426 TPWND-DGLSPETNVLSSTLSRYNELGVLTINSQPNVNAVPSTHPIYGWGDKGGYISQKA 484
Query: 281 YLEFFCSKDKLDTL-VEKSKAFPSITYMAVNK-SENWVSNTGESDVNAVTWGVFPAKEVI 108
YLEFF +K + L K P + Y +NK +N S+ NAVTWG+F KE+I
Sbjct: 485 YLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVTWGIFAGKEII 544
Query: 107 QPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SF VWKDEAF +W WA+LY + S
Sbjct: 545 QPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKS 579
[64][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 154 bits (390), Expect = 2e-36
Identities = 79/166 (47%), Positives = 106/166 (63%), Gaps = 4/166 (2%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + G +K PW + ET I +QL ++N LTINSQP VN A S P +GW
Sbjct: 373 FTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGW 431
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT--GESDVN 147
G GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V + + VN
Sbjct: 432 GPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVN 491
Query: 146 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 9
AVTWGVFP E+IQPT+VD SF WKDEAF +W+ W ++YPEDD
Sbjct: 492 AVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDD 536
[65][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 154 bits (390), Expect = 2e-36
Identities = 79/166 (47%), Positives = 106/166 (63%), Gaps = 4/166 (2%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + G +K PW + ET I +QL ++N LTINSQP VN A S P +GW
Sbjct: 352 FTDFIKGEVKRLPWCTEPPTE-ETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGW 410
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVE--KSKAFPSITYMAVNKSENWVSNT--GESDVN 147
G GG+VYQKAY+EFFC + +L+ L+ +++ + SI+YMAV + V + + VN
Sbjct: 411 GPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVN 470
Query: 146 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 9
AVTWGVFP E+IQPT+VD SF WKDEAF +W+ W ++YPEDD
Sbjct: 471 AVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN-EWMDVYPEDD 515
[66][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 154 bits (390), Expect = 2e-36
Identities = 79/155 (50%), Positives = 101/155 (65%), Gaps = 3/155 (1%)
Frame = -1
Query: 458 PWSEL-DGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
PW+E DG++ ET +I +QL NSNGFLTINSQPS+N A S P +GWG PGGY YQKA
Sbjct: 467 PWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKA 526
Query: 281 YLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSE--NWVSNTGESDVNAVTWGVFPAKEVI 108
YLEFF S+ + L ++ + VN +W +NT + AVTWGVFP E+
Sbjct: 527 YLEFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDW-TNTETTMPIAVTWGVFPGSEIA 585
Query: 107 QPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
QPT+VDP SF+VWKDEAF W +W+++Y E S
Sbjct: 586 QPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSS 619
[67][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 154 bits (388), Expect = 4e-36
Identities = 78/153 (50%), Positives = 97/153 (63%), Gaps = 1/153 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWS+ + L PET + E+L N NG LTINSQPS+NA S+ P GWG PGGYV+QKAY
Sbjct: 428 PWSDGE-LAPETIPLVEKLVHANQNGILTINSQPSLNAVPSEDPNHGWGKPGGYVFQKAY 486
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-ENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF ++ L + K I + VN S E+ +N NAVTWGVFP E++QP
Sbjct: 487 LEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNANMYSPNAVTWGVFPGSEILQP 546
Query: 101 TIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
T+VDP +F WKDEAF +W + W LYPE S
Sbjct: 547 TVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRS 579
[68][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 151 bits (381), Expect = 3e-35
Identities = 76/164 (46%), Positives = 98/164 (59%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F C + S PWS+L + E +I +QL +N N FLTINSQP++N KS P GW
Sbjct: 392 FARYCEKKISSLPWSDLP-ISDEADLIRDQLLSMNRNAFLTINSQPALNGEKSSHPVFGW 450
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G P GYV+QK Y+EFF L+ L E K S++Y NK+ + +N+ NAVTW
Sbjct: 451 GPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVTW 510
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFP +E+IQPTIV+ SF WKDEA+ + WAN Y D S
Sbjct: 511 GVFPNREIIQPTIVESTSFLAWKDEAYSL-GMEWANAYSPDSIS 553
[69][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 150 bits (379), Expect = 4e-35
Identities = 76/158 (48%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L S PWSE + E I L +N GFLTINSQP+VN AKS P GWG GY
Sbjct: 395 GKLDSLPWSE-QAITTEAGPIRSDLIDLNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE F S + + ++ + + P TY AVNK + +N NAVTWGVFP K
Sbjct: 454 VYQKAYLEVFVSPEYISEIITRLERDPEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGK 513
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIV+ SF WKDE + + + WAN + PS
Sbjct: 514 EIVQPTIVETVSFLAWKDEFYRL-GQQWANCHAGVSPS 550
[70][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 150 bits (378), Expect = 6e-35
Identities = 74/158 (46%), Positives = 98/158 (62%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G ++ PWS+ + PET I +L +N GFLTINSQP+VN KS P GWG GY
Sbjct: 396 GKVERLPWSD-SAVTPETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGY 454
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE + +D L+ + + P +TY VNK+ + + E NAVTWG+F +K
Sbjct: 455 VYQKAYLELLVPPEHVDELLRRIEKNPDLTYYCVNKTGELKARSDEGP-NAVTWGIFASK 513
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E+IQPTIV+ SF WKDEA+++ WA +P D PS
Sbjct: 514 EIIQPTIVESVSFMAWKDEAYQL-GEDWAKCHPADSPS 550
[71][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 148 bits (374), Expect = 2e-34
Identities = 75/156 (48%), Positives = 94/156 (60%)
Frame = -1
Query: 470 LKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVY 291
L+ PWSE + E ++I + L +N+ G +TINSQP+VN KS P GWG GYVY
Sbjct: 397 LEYLPWSEAP-ISSEAELIKDDLIALNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVY 455
Query: 290 QKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEV 111
QKAYLE S + + + + P ITY AV KS N +N NAVTWGVFP KE+
Sbjct: 456 QKAYLELLVSPELFPEIKRRIEDHPDITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEI 515
Query: 110 IQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+QPTIV+ SF WKDEAF++ WA Y D PS
Sbjct: 516 VQPTIVESISFLAWKDEAFQL-GLEWARCYDADTPS 550
[72][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 148 bits (374), Expect = 2e-34
Identities = 76/162 (46%), Positives = 103/162 (63%), Gaps = 11/162 (6%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+LKS PWS+ + +TK+I + L +N +GF T+NSQP++NA KS GWG GY
Sbjct: 400 GDLKSLPWSD-GPVGDDTKVIVDDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLV-----------EKSKAFPSITYMAVNKSENWVSNTGESDV 150
VYQK YLEFFC KD + L+ E S AF I+Y AV+K N +N + D+
Sbjct: 459 VYQKQYLEFFCHKDVVSKLLDHVEEFNVKGAESSSAF--ISYYAVDKDGNLSTNCKDDDI 516
Query: 149 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
NAVTWGVFP +E++QPTIV+ SF WKDE + +++ WA +
Sbjct: 517 NAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWAKI 557
[73][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 147 bits (372), Expect = 3e-34
Identities = 75/158 (47%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L+S PWSE + E I L +N GFLTINSQP+VN AKS P GWG GY
Sbjct: 395 GKLESLPWSE-QPITGEATSIRNDLIDLNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE S + + ++ + + P TY AVNK + +N NAVTWGVFP K
Sbjct: 454 VYQKAYLEVLVSPEYIAEIITRIERDPEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGK 513
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIV+ SF WKDE + + + WAN + PS
Sbjct: 514 EIVQPTIVETVSFLAWKDEFYRL-GQQWANCHGGASPS 550
[74][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 147 bits (372), Expect = 3e-34
Identities = 76/166 (45%), Positives = 97/166 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F ++S PWSE + E II L ++N GFLTINSQP+V+ KS P
Sbjct: 387 ELFVSYLENGIESLPWSEAP-ISSEADIIKSDLIELNRRGFLTINSQPAVDGVKSSDPVY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE + D + LV + + P +TY AV K+ + +N NAV
Sbjct: 446 GWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDLQTNAQSDGPNAV 505
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE++QPTIV+ SF WKDEAF + WA+ + PS
Sbjct: 506 TWGVFPGKEIVQPTIVETISFLAWKDEAFRL-GTDWAHCHSALSPS 550
[75][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 147 bits (372), Expect = 3e-34
Identities = 76/160 (47%), Positives = 102/160 (63%), Gaps = 9/160 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G LKS PWS+ + +T ++ E L +N GFLT+NSQP++NA KS GWG GY
Sbjct: 400 GELKSLPWSD-GPIGEDTSVMVENLINLNHKGFLTMNSQPALNAVKSSEKVYGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLV------EKSKAFPS---ITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFFC KD L L+ KS+ S I+Y AV+K+ N +N + D+NA
Sbjct: 459 VYQKQYLEFFCPKDLLPKLLHTIDSYNKSEGDASSSIISYYAVDKNGNLSTNCKDDDINA 518
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
VTWGVFP +E++QPTIV+ SF WKDE + +++ W N+
Sbjct: 519 VTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWTNI 557
[76][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 147 bits (371), Expect = 4e-34
Identities = 72/160 (45%), Positives = 103/160 (64%), Gaps = 9/160 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+LKS PWS+ + +T++I + L +N +GF T+NSQP++NA KS GWG GY
Sbjct: 400 GDLKSLPWSD-GPVGDDTRVIVDDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFFC KD + L+++ + F I+Y AV+K N +N + D+NA
Sbjct: 459 VYQKQYLEFFCHKDVVSKLLDQVEEFNIKGAESSSAFISYYAVDKDGNLSTNCKDDDINA 518
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
VTWGVFP +E++QPTIV+ SF WKDE + +++ WA +
Sbjct: 519 VTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EWAKI 557
[77][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 146 bits (369), Expect = 6e-34
Identities = 77/158 (48%), Positives = 100/158 (63%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L S PWS++ + E + I Q+ ++N+ G LTINSQP+VN AKS P GWG GY
Sbjct: 395 GKLASLPWSDVP-ISNEIETIKPQILELNNRGILTINSQPAVNGAKSTHPVHGWGPKNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE + + + LV+K + IT+ AVNK+ N +N NAVTWG++P K
Sbjct: 454 VYQKAYLELLVTPEVAEKLVKKLENQSEITFYAVNKTGNLQTN-APGGPNAVTWGIYPGK 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
EVIQPTIV+ SF WK+EAF + S WA YP + S
Sbjct: 513 EVIQPTIVEKISFLAWKEEAFRLGS-EWAKCYPAESES 549
[78][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 146 bits (369), Expect = 6e-34
Identities = 73/158 (46%), Positives = 98/158 (62%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWSE + E+ II + L +N+ GFLTINSQP++N AKS P GWG GY
Sbjct: 395 GKLDRLPWSE-SAITQESDIIKDDLIALNNRGFLTINSQPAINGAKSSHPIYGWGPKNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE S +D ++ + + P +TY +NK+ +N+ ++ NAVTWG+F +K
Sbjct: 454 VYQKAYLELLISPTLIDEVIRRIETNPDLTYHCINKNGELRTNSSDTP-NAVTWGIFASK 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
EVIQPTIV+ SF WKDEA+ + WA + PS
Sbjct: 513 EVIQPTIVETVSFLAWKDEAYRL-GDDWAKCHDASSPS 549
[79][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 144 bits (363), Expect = 3e-33
Identities = 72/159 (45%), Positives = 100/159 (62%), Gaps = 8/159 (5%)
Frame = -1
Query: 473 NLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYV 294
+LKS PWS+ + +T II ++L +N GFLT+NSQPS+N KS+ GWG GYV
Sbjct: 141 DLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDKVYGWGPKNGYV 199
Query: 293 YQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSENWVSNTGESDVNAVT 138
+QK YLEFFC +D L+E + F +TY A +K+ +NT E D+NAVT
Sbjct: 200 FQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTKEDDINAVT 259
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
WGVFP +E++QPTIV+ SF WKDE + + + W ++Y
Sbjct: 260 WGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVY 297
[80][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 144 bits (363), Expect = 3e-33
Identities = 70/164 (42%), Positives = 97/164 (59%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
FK +G + PW + ++ ETK I ++L K+ + T+ SQP+VNAA S GW
Sbjct: 432 FKRHVLGETTAIPWID-QPVEAETKTIGDKLAKLIEKKWWTVGSQPAVNAAPSSHAIFGW 490
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GG+V+QKA++E F S + L ++ P ITY+A N + +N NAVTW
Sbjct: 491 GPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNASLDSANAVTW 550
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GVFP +E+IQ TI+ P SF+ W+DEA+ IW WA LYP PS
Sbjct: 551 GVFPGREIIQSTIIAPVSFQAWRDEAYSIWG-EWARLYPAGTPS 593
[81][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 144 bits (363), Expect = 3e-33
Identities = 72/159 (45%), Positives = 100/159 (62%), Gaps = 8/159 (5%)
Frame = -1
Query: 473 NLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYV 294
+LKS PWS+ + +T II ++L +N GFLT+NSQPS+N KS+ GWG GYV
Sbjct: 141 DLKSLPWSD-GPIGEDTAIIVDKLISLNQRGFLTMNSQPSLNCVKSNDKVYGWGPKNGYV 199
Query: 293 YQKAYLEFFCSKDKLDTLVEKSKAFPS--------ITYMAVNKSENWVSNTGESDVNAVT 138
+QK YLEFFC +D L+E + F +TY A +K+ +NT E D+NAVT
Sbjct: 200 FQKQYLEFFCHRDIFPKLLESIEKFNEKGGESCSFLTYYAADKNGELNTNTKEDDINAVT 259
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
WGVFP +E++QPTIV+ SF WKDE + + + W ++Y
Sbjct: 260 WGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EWGSVY 297
[82][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 144 bits (362), Expect = 4e-33
Identities = 73/161 (45%), Positives = 93/161 (57%), Gaps = 1/161 (0%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G++ PW E LQPE+ +I QL K+N GFLT+NSQP V+ S
Sbjct: 388 EVFARYVEGSVPHIPWCETP-LQPESFLIQPQLAKLNRYGFLTVNSQPPVDGLPSCHKVF 446
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKS-ENWVSNTGESDVNA 144
GWGG GG VYQKAY E F S K + L + PS+ AVN + + E V A
Sbjct: 447 GWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDHPSLNMYAVNNAGQELRVGVEEGGVTA 506
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
+TWGVFP +E++QPTI DP +F +W +EAF +W W NLY
Sbjct: 507 LTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWGSMWLNLY 547
[83][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 144 bits (362), Expect = 4e-33
Identities = 70/160 (43%), Positives = 99/160 (61%), Gaps = 9/160 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L S PW + + +T II + L ++N N +T+NSQPS+N+ +S GWG GY
Sbjct: 400 GQLNSLPWFD-GAIGEDTNIILDHLIELNENSLITLNSQPSLNSVRSSDKVFGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFFC KD + L++ + I+Y AVNK+ N +SN + D+NA
Sbjct: 459 VYQKQYLEFFCHKDVVARLLDHIDQYNKNQGDSTSAVISYYAVNKNGNLISNCQDDDINA 518
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
VTWGVFP +E++QPTIV+ SF WKDE + ++S W+ +
Sbjct: 519 VTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS-EWSKI 557
[84][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 143 bits (360), Expect = 7e-33
Identities = 75/166 (45%), Positives = 92/166 (55%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F ++S PWSE L E I + L ++N G LTINSQP+VN KS P
Sbjct: 387 ELFVSYLNNKIESLPWSE-SPLTTEADEIRDDLIELNKRGLLTINSQPAVNGVKSSHPIH 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQK+YLE D ++ + + P +TY AV K SN NAV
Sbjct: 446 GWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYYAVTKDGELRSNVTSDGPNAV 505
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWGVFP KE++QPTIV+ SF WKDEAF + WA+ Y PS
Sbjct: 506 TWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GVDWAHCYDISSPS 550
[85][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 143 bits (360), Expect = 7e-33
Identities = 74/158 (46%), Positives = 95/158 (60%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWSE + ET I + L +N+ GFLTINSQP+VN S P GWG GY
Sbjct: 395 GGLDRLPWSE-SPITEETDDIKQDLIDLNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE + + ++ + + P +TY A+NK+ +NT +S NAVTWG+F +K
Sbjct: 454 VYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVTWGIFASK 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
EVIQPTIV+ SF WKDEAF + WA + PS
Sbjct: 513 EVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPS 549
[86][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 143 bits (360), Expect = 7e-33
Identities = 75/166 (45%), Positives = 97/166 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G L PWSE + ET II L +NS GFLTINSQP+++ S P
Sbjct: 387 EIFIHFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHPVY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA +P PS
Sbjct: 505 TWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPS 549
[87][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 143 bits (360), Expect = 7e-33
Identities = 75/166 (45%), Positives = 97/166 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G L PWSE + ET II L +NS GFLTINSQP+++ S P
Sbjct: 387 EIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHPVY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTSDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA +P PS
Sbjct: 505 TWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPS 549
[88][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 142 bits (359), Expect = 9e-33
Identities = 71/152 (46%), Positives = 92/152 (60%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWSE + E +I + L ++N+ G +T+NSQP+VN KS P GWG GYVYQKAY
Sbjct: 401 PWSEAP-VAEEADLIKDDLIELNNRGLITVNSQPAVNGVKSTHPIHGWGPANGYVYQKAY 459
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPT 99
LE S + + + ++ P +TY AV KS N +N NAVTWGVFP KE++QPT
Sbjct: 460 LEMLISPELFPQIKSRIESHPDLTYHAVTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPT 519
Query: 98 IVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
IV+ SF WKDEAF++ WA Y PS
Sbjct: 520 IVERISFLAWKDEAFQL-GMEWARCYETGTPS 550
[89][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 142 bits (359), Expect = 9e-33
Identities = 73/166 (43%), Positives = 97/166 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F GNL PWS+ + PET I + L ++N GF TINSQP+VN KS P
Sbjct: 387 EVFVRFLEGNLDRLPWSD-SPITPETSAIKDALVELNRRGFFTINSQPAVNGVKSSHPVF 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG G+VYQKAYLE +D L+ + +A +TY AV K +NT +S NA+
Sbjct: 446 GWGPKNGFVYQKAYLELLVPPYVIDELIARIEANEDLTYHAVTKKGELRTNTRDSP-NAL 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +EV+QPTIV+ SF WKDEA+++ WA + P+
Sbjct: 505 TWGIFAGREVVQPTIVETVSFLAWKDEAYQL-GEDWAKCHEASSPT 549
[90][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 142 bits (359), Expect = 9e-33
Identities = 71/158 (44%), Positives = 97/158 (61%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L+ PWS+ + ET I +L +N GFLTINSQP+VN KS P GWG G+
Sbjct: 396 GKLERLPWSD-SSVTLETSDIQNELLDLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGF 454
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE + ++ L+ + + P +TY +NK+ + + E NAVTWG+F +K
Sbjct: 455 VYQKAYLELLVPPEHVEELLRRIEKNPDLTYYCINKTGELRARSDEGP-NAVTWGIFASK 513
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E+IQPTIV+ SF WKDEA+++ WA +P D PS
Sbjct: 514 EIIQPTIVESVSFMAWKDEAYQL-GDDWAKCHPADSPS 550
[91][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 142 bits (358), Expect = 1e-32
Identities = 74/158 (46%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWSE + ET I L +N+ GFLTINSQP+VN S P GWG GY
Sbjct: 395 GGLDRLPWSE-SPITEETDDIKHDLIDLNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE + + ++ + + P +TY A+NK+ +NT +S NAVTWG+F +K
Sbjct: 454 VYQKAYLELLIPPEVIGEVIRRIEKNPDLTYYAINKNGELKTNTSDSP-NAVTWGIFASK 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
EVIQPTIV+ SF WKDEAF + WA + PS
Sbjct: 513 EVIQPTIVETVSFLAWKDEAFRL-GDDWAKCHDARSPS 549
[92][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 142 bits (358), Expect = 1e-32
Identities = 72/152 (47%), Positives = 94/152 (61%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWSE + ET II + L +N+ GFLTINSQP++N A S P GWG GYVYQKAY
Sbjct: 401 PWSE-SSITEETDIIKQDLIDLNNRGFLTINSQPAINGASSSHPVYGWGPKNGYVYQKAY 459
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPT 99
LE + +D ++ + + +TY A NK+ +NT +S NAVTWG+F +KEVIQPT
Sbjct: 460 LELLIPPEIIDEVITRIQKNADLTYYATNKNGELKTNTSDSP-NAVTWGIFASKEVIQPT 518
Query: 98 IVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
IV+ SF WKDEA+ + WA + PS
Sbjct: 519 IVETVSFLAWKDEAYRL-GDDWAKCHDARSPS 549
[93][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 142 bits (358), Expect = 1e-32
Identities = 75/166 (45%), Positives = 97/166 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G L PWSE + ET II L +NS GFLTINSQP+++ S P
Sbjct: 387 EIFIRFLNGKLDRLPWSE-GAVTEETDIIKRDLLDLNSRGFLTINSQPAIDGVHSSHPVY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S ++ ++ + + +TY VNK+ +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNADLTYYCVNKTGELRTNTTDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA +P PS
Sbjct: 505 TWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHPASSPS 549
[94][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 142 bits (358), Expect = 1e-32
Identities = 69/154 (44%), Positives = 98/154 (63%), Gaps = 9/154 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+LKS PWS+ + +TK+I + L ++N G LT+NSQP++N+ KS GWG GY
Sbjct: 401 GDLKSLPWSD-GSVGDDTKVIVDDLVELNKRGLLTMNSQPALNSIKSSEKIFGWGPKNGY 459
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPS---------ITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFFC KD + L++ + + I+Y AV+ N +N + D+NA
Sbjct: 460 VYQKQYLEFFCHKDIIVKLLQTIDDYNNNQGDASSAIISYYAVDLKGNLTTNCNDDDINA 519
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWS 42
VTWGVFP +E++QPTIV+ SF WKDE + ++S
Sbjct: 520 VTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFS 553
[95][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 142 bits (357), Expect = 2e-32
Identities = 72/152 (47%), Positives = 91/152 (59%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWSE L E + I + L +N G +TINSQP+VN +S P GWG P GYVYQKAY
Sbjct: 396 PWSE-SPLDAEAEQIRDDLIDLNLRGLITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAY 454
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPT 99
LE + L E+ P +TY AV KS N +N NAVTWGVFP KE++QPT
Sbjct: 455 LELLVHPAIFEQLKERIHDHPDLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPT 514
Query: 98 IVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+V+ SF WKDEAF++ WA + ++ PS
Sbjct: 515 VVENISFLAWKDEAFQL-GMEWARCHDQNTPS 545
[96][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 141 bits (356), Expect = 2e-32
Identities = 72/164 (43%), Positives = 99/164 (60%), Gaps = 8/164 (4%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
GNL S PWS+ + E ++ + L +N G LTINSQP VN S+ GWG G+
Sbjct: 393 GNLSSLPWSDGE-TSKEINVLLDDLLALNRQGILTINSQPCVNGLPSNHNVHGWGPSNGF 451
Query: 296 VYQKAYLEFFCSKDKLDTLVEK--------SKAFPSITYMAVNKSENWVSNTGESDVNAV 141
VYQK YLEFF L L+ S F ++T+ AVN ++N+ E D+NAV
Sbjct: 452 VYQKQYLEFFIPAKFLTKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNSKEDDINAV 511
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDD 9
TWG+FP KEV+QPTIV+ SF WKDEAF ++ ++W++L+ + D
Sbjct: 512 TWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KAWSSLFKDQD 554
[97][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 141 bits (356), Expect = 2e-32
Identities = 74/166 (44%), Positives = 96/166 (57%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F GNL PWSE + ET ++ L +N GFLTINSQP+++ S P
Sbjct: 387 EIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHPVY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKKGELRTNTTDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA + PS
Sbjct: 505 TWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPS 549
[98][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 141 bits (356), Expect = 2e-32
Identities = 72/152 (47%), Positives = 91/152 (59%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWSE + E +I + L +N G +T+NSQP+VN KS P GWG GYVYQKAY
Sbjct: 401 PWSEAP-VAEEADLIKDYLLDLNKRGLITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAY 459
Query: 278 LEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPT 99
LE S + + ++ + P +TY AV KS +N NAVTWGVFP KE++QPT
Sbjct: 460 LELLVSPEVYPEIKKRIENHPDLTYHAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPT 519
Query: 98 IVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
IV+ SF WKDEAF++ S WA Y D PS
Sbjct: 520 IVERISFLAWKDEAFQLGS-DWARCYEADTPS 550
[99][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 141 bits (356), Expect = 2e-32
Identities = 75/166 (45%), Positives = 96/166 (57%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F GNL PWSE + ET +I L +N GFLTINSQP+++ S P
Sbjct: 373 EIFVRFLNGNLDRLPWSE-GAVTEETDVIKLDLLDLNRRGFLTINSQPAIDGMPSSHPVY 431
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAV
Sbjct: 432 GWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAV 490
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA + PS
Sbjct: 491 TWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHGASSPS 535
[100][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 140 bits (354), Expect = 3e-32
Identities = 74/166 (44%), Positives = 96/166 (57%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F GNL PWSE + ET ++ L +N GFLTINSQP+++ S P
Sbjct: 278 EIFVRFLNGNLDRLPWSE-GAVTEETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHPVY 336
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S +D ++ + + P +TY VNK +NT +S NAV
Sbjct: 337 GWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELRTNTTDSP-NAV 395
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA + PS
Sbjct: 396 TWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCHVASSPS 440
[101][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 140 bits (352), Expect = 6e-32
Identities = 70/158 (44%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWS+ + E I + L ++NS G LT+NSQP+VN +S P GWG G+
Sbjct: 395 GKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGF 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIVD SF WKDEA+ + WA + PS
Sbjct: 513 EIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPS 549
[102][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 140 bits (352), Expect = 6e-32
Identities = 70/158 (44%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWS+ + E I + L ++NS G LT+NSQP+VN +S P GWG G+
Sbjct: 395 GKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGF 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIVD SF WKDEA+ + WA + PS
Sbjct: 513 EIVQPTIVDTISFLAWKDEAYRL-GEDWAKCHDASSPS 549
[103][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 139 bits (351), Expect = 8e-32
Identities = 70/164 (42%), Positives = 98/164 (59%), Gaps = 9/164 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L S PWS+ + +++II + L +N GF T+NSQPS+NA KS+ GWG GY
Sbjct: 400 GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSNDKVYGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFF KD + L+ + + +TY AV++ SNT + D+NA
Sbjct: 459 VYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNTKDDDINA 518
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
VTWGVFP +E++QPTIV+ SF WKDE + + + W ++ D
Sbjct: 519 VTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSD 561
[104][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 139 bits (351), Expect = 8e-32
Identities = 70/164 (42%), Positives = 98/164 (59%), Gaps = 9/164 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L S PWS+ + +++II + L +N GF T+NSQPS+NA KS+ GWG GY
Sbjct: 400 GKLNSLPWSD-SAIGQDSEIIVDNLIALNKKGFFTLNSQPSLNAIKSNDKVYGWGPKNGY 458
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAF---------PSITYMAVNKSENWVSNTGESDVNA 144
VYQK YLEFF KD + L+ + + +TY AV++ SNT + D+NA
Sbjct: 459 VYQKQYLEFFVHKDIIPALLHQIDNYNRGQGDSNSSVLTYYAVDQKGKLFSNTKDDDINA 518
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
VTWGVFP +E++QPTIV+ SF WKDE + + + W ++ D
Sbjct: 519 VTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EWIKIFQSD 561
[105][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 139 bits (349), Expect = 1e-31
Identities = 69/164 (42%), Positives = 99/164 (60%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F++ G L++ PWSE GL PET I +QL +N+ G+ T+ SQP+VN +S P GW
Sbjct: 350 FRKHLEGELEALPWSE-QGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGW 408
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYV+QK ++EFF + L + A +TY A N + ++ +++ ES VN VTW
Sbjct: 409 GPKNGYVFQKPFVEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEES-VNPVTW 467
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G F KE++ PTI++ SF+ W +EAF IW R W +YP S
Sbjct: 468 GTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REWQRIYPTKSAS 510
[106][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 138 bits (348), Expect = 2e-31
Identities = 69/158 (43%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWS+ + E I + L ++NS G LT+NSQP+VN +S P GWG G+
Sbjct: 395 GKLDRLPWSD-SPISGEANAIKDNLVQLNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGF 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE F LD L+ + + P +TY AV K+ +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELFVPPYLLDELIARIEKNPDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIV+ SF WKDEA+ + WA + PS
Sbjct: 513 EIVQPTIVETISFLAWKDEAYRL-GEDWAKCHDASSPS 549
[107][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 138 bits (347), Expect = 2e-31
Identities = 68/161 (42%), Positives = 99/161 (61%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+++S PW +L GL PET +I E+L ++N G+LT+ SQP NA+ S GWG G+
Sbjct: 454 GSIQSLPWCDL-GLSPETALIQEELIQLNYRGYLTLASQPCTNASSSTDKIFGWGPSKGH 512
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAF---PSITYMAVNKSENWVSNTGESDVNAVTWGVF 126
VYQKA++E F + + T+++ + +Y A + ++ +N N VTWGVF
Sbjct: 513 VYQKAFIEMFVHRQQWKTILKPKLDYYGRRKFSYYAGDSKGSFETNLDPHSSNVVTWGVF 572
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P +VIQ TI++ SFK W+DEAF IWS WA L+P + PS
Sbjct: 573 PNSQVIQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPS 612
[108][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 137 bits (346), Expect = 3e-31
Identities = 70/156 (44%), Positives = 90/156 (57%)
Frame = -1
Query: 470 LKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVY 291
+ S PWSE L E I + L ++N G LT+NSQP+VN KS GWG GYVY
Sbjct: 397 IDSLPWSE-SPLTSEADEIRDDLVELNKRGLLTVNSQPAVNGVKSSHAVHGWGPSNGYVY 455
Query: 290 QKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEV 111
QK+YLE D + ++ + + P +T+ AV K SN NAVTWGVFP KE+
Sbjct: 456 QKSYLELLVHPDVFNDMIGRIENHPDLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEI 515
Query: 110 IQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+QPTIV+ SF WKDEAF + WA+ Y + PS
Sbjct: 516 VQPTIVESISFLAWKDEAFRL-GVDWAHCYDANSPS 550
[109][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 137 bits (346), Expect = 3e-31
Identities = 75/159 (47%), Positives = 98/159 (61%), Gaps = 1/159 (0%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F C L PWS++ L E+ II ++L ++N G LTINSQP V AA S P GW
Sbjct: 397 FAAYCERKLACLPWSDIP-LSGESAIIADKLAELNRQGILTINSQPPVCAAPSTDPLFGW 455
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDV-NAVT 138
G GYV+QKAYLEFF D++ +L+E +F ++ Y + E + GE DV +AVT
Sbjct: 456 GPAHGYVFQKAYLEFFMHPDQVKSLLEVIPSFKTVQYY-ITDYEGSLETNGELDVPSAVT 514
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
WGVFP EVIQPT+V+ ASF WKDEA+ + SWA +
Sbjct: 515 WGVFPNSEVIQPTVVESASFLAWKDEAYSL-GLSWAKAH 552
[110][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 137 bits (345), Expect = 4e-31
Identities = 70/161 (43%), Positives = 101/161 (62%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+L++ PWS+L GL ET +I E+L ++N G+L++ SQP+ N+ S GWG PGGY
Sbjct: 470 GSLEALPWSDL-GLSAETALIQEELIQLNERGYLSLASQPATNSTPSTDKIFGWGPPGGY 528
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFP---SITYMAVNKSENWVSNTGESDVNAVTWGVF 126
VYQK+++E F K + + L K K P ++Y + +E + +N S + VTWGVF
Sbjct: 529 VYQKSFVEMFVHKQQWE-LEIKPKLEPLGSKVSYYVGDSAETFYTNLDSSCSSVVTWGVF 587
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P EV+Q TIV+ SFK W+DEAF IW W+ L+P + S
Sbjct: 588 PNSEVLQTTIVEEESFKAWRDEAFSIW-LEWSKLFPRNSRS 627
[111][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 137 bits (345), Expect = 4e-31
Identities = 65/164 (39%), Positives = 100/164 (60%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F++ + ++ + PW + + ++ ETK I + L K+N N + T+ SQP+VN A S P GW
Sbjct: 445 FQKHIMSDISAIPWID-EPVEVETKTIAKYLLKLNGNSWWTVGSQPAVNGAPSADPVFGW 503
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GG V+QKA++E F + L + K P +TY A N +++N + +AVTW
Sbjct: 504 GPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTYYAGNNKSEFLTNAPKDGASAVTW 563
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
GV+P +E+IQ TI+ SFK W E+F++W WANLY ++ PS
Sbjct: 564 GVYPGREIIQSTIIAEVSFKAWLSESFQVWG-EWANLYSKNTPS 606
[112][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 136 bits (343), Expect = 7e-31
Identities = 72/160 (45%), Positives = 94/160 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G+L PWSE + ET+II L +N GFLTINSQP+++ S P
Sbjct: 387 EIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHPIY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S +D ++ + + +TY VNK +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA +
Sbjct: 505 TWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCH 543
[113][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 136 bits (343), Expect = 7e-31
Identities = 72/160 (45%), Positives = 94/160 (58%)
Frame = -1
Query: 500 EKFKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAI 321
E F G+L PWSE + ET+II L +N GFLTINSQP+++ S P
Sbjct: 387 EIFIRFLNGSLDRLPWSE-GAVTEETEIIKSDLLDLNRKGFLTINSQPAIDGMPSSHPIY 445
Query: 320 GWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAV 141
GWG GYVYQKAYLE S +D ++ + + +TY VNK +NT +S NAV
Sbjct: 446 GWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKKGELKTNTTDSP-NAV 504
Query: 140 TWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
TWG+F +KE+IQPTIV+ SF WKDEA+ + WA +
Sbjct: 505 TWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDWAKCH 543
[114][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 136 bits (343), Expect = 7e-31
Identities = 71/158 (44%), Positives = 94/158 (59%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWS+ + E K I L ++N+ G LTINSQP+VN AKS P GWG G+
Sbjct: 395 GKLSRLPWSDTP-ISSEAKAIKPNLIELNNRGILTINSQPAVNGAKSSHPVYGWGPKNGF 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE LD L+ + + +TY AV+K+ +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
EV+QPTIV+ SF WKDEA+ + WA + PS
Sbjct: 513 EVVQPTIVETISFLAWKDEAYRL-GEDWAKCHAATSPS 549
[115][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 136 bits (343), Expect = 7e-31
Identities = 71/164 (43%), Positives = 93/164 (56%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F G L PWS+ + E I E L K+N GFLTINSQP+VN KS P GW
Sbjct: 389 FVNFLTGKLDRLPWSD-SPITTEAHEIQEDLLKLNQRGFLTINSQPAVNGVKSSHPVYGW 447
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G G+VYQKAYLE + +D L+ + + +TY A NK +NT +S NA+TW
Sbjct: 448 GPKNGFVYQKAYLELLVPSNLIDELITRIEKNDDLTYHATNKKGELKTNTRDSP-NALTW 506
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G+F +E+IQPTIV+ SF WKDEA+ + W+ + PS
Sbjct: 507 GIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHWSKCHDAASPS 549
[116][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 136 bits (342), Expect = 9e-31
Identities = 67/159 (42%), Positives = 95/159 (59%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F+ G+L++ PWSE GL PET I+ QL +N+ G+ T+ SQP+VN KS P GW
Sbjct: 460 FRRHIEGDLEAIPWSE-QGLSPETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGW 518
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G GYV+QK ++EFF + K +A +T+ A N + + ++ E VN VTW
Sbjct: 519 GPKNGYVFQKPFVEFFIPAAEFQAFKPKLQAHDQVTWFAGNAAGAFEASQ-EDGVNPVTW 577
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 18
G F KE++ PTI++ SF+ W DEAF IW + W +YP
Sbjct: 578 GTFAGKEIVTPTIIEAVSFRSWLDEAFSIW-KEWQRIYP 615
[117][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 136 bits (342), Expect = 9e-31
Identities = 71/161 (44%), Positives = 100/161 (62%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G++ + PW +L GL PET +I E+L ++N G+LT+ SQP+ NA+ S GWG GY
Sbjct: 454 GSISALPWCDL-GLSPETALIQEELIQLNQRGYLTLASQPATNASPSTDKIFGWGPKNGY 512
Query: 296 VYQKAYLEFFCSKDKLDTLVE-KSKAFP--SITYMAVNKSENWVSNTGESDVNAVTWGVF 126
VYQKA++E F K + + +V+ K +P +Y + S ++ SN + N VTWGVF
Sbjct: 513 VYQKAFVEMFILKKQWEAIVKPKLDHYPRGKFSYYVGDSSGSFESNLETNSSNVVTWGVF 572
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P VIQ TIV+ SFK W+DEAF IW WA L+P ++ S
Sbjct: 573 PNSPVIQTTIVEEESFKAWRDEAFCIW-LEWAKLFPSNELS 612
[118][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 135 bits (340), Expect = 1e-30
Identities = 62/132 (46%), Positives = 87/132 (65%), Gaps = 1/132 (0%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ + L ET ++ E+L ++N G LTINSQP++N S P +GWG GGYV+QKAY
Sbjct: 484 PWND-EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAY 542
Query: 278 LEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQP 102
LEFF S++ + L++ K + + Y VN ++N E NAVTWG+FP +E+IQP
Sbjct: 543 LEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQP 602
Query: 101 TIVDPASFKVWK 66
T+VDP SF WK
Sbjct: 603 TVVDPVSFMFWK 614
[119][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 135 bits (340), Expect = 1e-30
Identities = 65/159 (40%), Positives = 97/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G++++ PW +L GL PET +I E+L +N GFLT+ SQP+ N+ S GWG PGG
Sbjct: 445 GSIEALPWCDL-GLSPETALIQEELIGLNQRGFLTLASQPATNSTPSADKIFGWGPPGGV 503
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFP--SITYMAVNKSENWVSNTGESDVNAVTWGVFP 123
VYQKA++E F K + + ++ P +Y + + ++ SN + VTWGVFP
Sbjct: 504 VYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGDSAGSFASNMAPESSSVVTWGVFP 563
Query: 122 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
+++Q TI++ SFK W+DEAF IW SW+ L+P + P
Sbjct: 564 NSQILQTTIIEEESFKAWRDEAFSIW-LSWSKLFPRNSP 601
[120][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 135 bits (340), Expect = 1e-30
Identities = 70/158 (44%), Positives = 105/158 (66%), Gaps = 4/158 (2%)
Frame = -1
Query: 464 SSPWSELDGLQPETKIINEQLGKINSNGFL--TINSQPSVNAAKSDSPAIGWGGPGGYVY 291
++P+ +L L PE+ +I L +NS T+ SQP+V+AAKS+ +GWG GGYV+
Sbjct: 442 TTPFCDLP-LSPESHMILPHLLALNSANVQHWTVGSQPAVDAAKSEDEVVGWGPRGGYVF 500
Query: 290 QKAYLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
QKA++EFF ++D+++ L EK + IT A N+ ++ +NT + VNAVTWGVFP +
Sbjct: 501 QKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDFKTNTDKDSVNAVTWGVFPGQ 560
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E+ Q TI++ SF WK+EAF+IW+ W+ LYP + PS
Sbjct: 561 EIAQSTIIEETSFLAWKEEAFDIWA-EWSLLYPRNTPS 597
[121][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 134 bits (338), Expect = 2e-30
Identities = 71/165 (43%), Positives = 95/165 (57%), Gaps = 1/165 (0%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + +G L PWS+ L PET +I EQL ++N G T+ SQP+ NA KSD GW
Sbjct: 429 FADTIVGKLPFMPWSD-QTLSPETMLIQEQLMELNQKGIWTVASQPACNALKSDDNIFGW 487
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWV-SNTGESDVNAVT 138
G GGYV+QK++ EFF S ++ L A + V KS+ V +N E N VT
Sbjct: 488 GPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVSERASNGVT 547
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
WGVFP +E++Q TI+ SF W++EAF IWS W LY ++ S
Sbjct: 548 WGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALYKKNTAS 591
[122][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 134 bits (338), Expect = 2e-30
Identities = 72/167 (43%), Positives = 103/167 (61%), Gaps = 14/167 (8%)
Frame = -1
Query: 470 LKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVY 291
+K+ PWS+ + +T ++ + L +N G T+NSQP+++A +S+ GWG G+VY
Sbjct: 404 VKALPWSD-GPIGEDTTVLKDALIALNRKGLFTLNSQPALSAVRSNDKLYGWGPKNGFVY 462
Query: 290 QKAYLEFFCSKDKLDTL---VEKSKA---FPSITYMAVNKSENWVSNTGESDVNAVTWGV 129
QK YLEF KDKL L VEK A + ITY AV+KS N +N+ D+NAVTWGV
Sbjct: 463 QKQYLEFLVRKDKLKELLDIVEKHNAKDTYGLITYYAVDKSGNLHTNSKNDDINAVTWGV 522
Query: 128 FPAKEVIQPTIVDPASFKVWKDEAFEI---W-----SRSWANLYPED 12
FP +E++QPTIV+ SF WKDE + + W S++ ++ PED
Sbjct: 523 FPGEEILQPTIVEKVSFLAWKDEVYSLLDEWITIFHSKAITDIVPED 569
[123][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 134 bits (336), Expect = 4e-30
Identities = 70/145 (48%), Positives = 90/145 (62%), Gaps = 2/145 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+LK PWS++ L E + + L ++N + LTINSQP VN A S P +GWG GY
Sbjct: 408 GDLKCLPWSDVP-LHQEADALLDSLIRLNEHLVLTINSQPKVNGAPSADPIVGWGPANGY 466
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKA-FPSITYMAVNKSENWVSN-TGESDVNAVTWGVFP 123
VYQK YLEF K L A FP++TY AV+ +N SN ++ NAVTWG+FP
Sbjct: 467 VYQKQYLEFLLPKHHLPAFHAALTADFPTLTYFAVDADDNLASNHPDDTQANAVTWGIFP 526
Query: 122 AKEVIQPTIVDPASFKVWKDEAFEI 48
+EV+QPTIV+ ASF WKDE + I
Sbjct: 527 GREVLQPTIVEKASFLAWKDEFYRI 551
[124][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 134 bits (336), Expect = 4e-30
Identities = 67/145 (46%), Positives = 83/145 (57%)
Frame = -1
Query: 437 LQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSK 258
L E I E L +N G +TINSQP+VN KS GWG GYVYQK+YLE
Sbjct: 115 LTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHP 174
Query: 257 DKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASF 78
D ++ + + P +TY AV KS N N NAVTWGVFP KE++QPTIV+ SF
Sbjct: 175 DLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISF 234
Query: 77 KVWKDEAFEIWSRSWANLYPEDDPS 3
WKDEAF + WA+ + + PS
Sbjct: 235 VAWKDEAFRL-GLDWAHCFEQSSPS 258
[125][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 133 bits (335), Expect = 6e-30
Identities = 68/158 (43%), Positives = 92/158 (58%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L+ PWS+ + E I E L ++N G LT+NSQP+VN +S P GWG G+
Sbjct: 395 GKLERLPWSD-SPISAEANAIKENLIELNGRGLLTVNSQPAVNGVRSSHPVYGWGPKNGF 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE F LD L+ + + +TY AV K +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELFVPPYLLDELIARIEKNDDLTYHAVAKEGELRTNTRDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIV+ SF WKDEA+ + WA + PS
Sbjct: 513 EIVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAASPS 549
[126][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 132 bits (332), Expect = 1e-29
Identities = 69/164 (42%), Positives = 95/164 (57%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + G L PWS+ + E I ++L ++N G TINSQP+VN A+S P GW
Sbjct: 389 FVKFMQGELARLPWSDTP-ISGEANAIKDKLIELNKRGLFTINSQPAVNGARSSHPVYGW 447
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTW 135
G G+VYQKAYLE LD L+ + + +TY AV+K+ +NT +S NA+TW
Sbjct: 448 GPKNGFVYQKAYLELLVPPYLLDELIARIEKNEDLTYHAVSKTGELRTNTRDSP-NALTW 506
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
G+F +EV+QPTIV+ SF WKDEA+ + WA + PS
Sbjct: 507 GIFAGREVVQPTIVETISFLAWKDEAYRL-GEDWAKCHEAGSPS 549
[127][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 132 bits (332), Expect = 1e-29
Identities = 68/171 (39%), Positives = 99/171 (57%), Gaps = 13/171 (7%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE +G PET I +QL K+NS G+ ++ SQP+VN +S P GWG G+
Sbjct: 490 GELTTIPWSE-EGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTFGWGPANGF 548
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSK---AFPSITYMAVNKSENWVSN----------TGES 156
V+QKA++EFF L +K + + + A+N + ++VS+ E+
Sbjct: 549 VFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSLEAEGEKEA 608
Query: 155 DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
NAVTWGVFP KE++ PTI++ SF+ W +EAF IW WA +Y + S
Sbjct: 609 STNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIYGKGSES 658
[128][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 130 bits (326), Expect = 6e-29
Identities = 70/159 (44%), Positives = 92/159 (57%), Gaps = 1/159 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G LK PW ++ L E QL +N + LT+NSQP VN A S +GWG GY
Sbjct: 405 GKLKCLPWCDV-ALNHEVDTTMPQLLDLNKHMILTLNSQPRVNGASSADKIVGWGPNNGY 463
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVFPA 120
VYQK YLEF K KL L + PS+TY AV+ ++ SN ++ NAVTWG+FP
Sbjct: 464 VYQKQYLEFLLPKSKLSQLRDFVNDMPSLTYFAVDSADELHSNHPDDTAANAVTWGIFPG 523
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
+EV+QPTIV+ SF WK+E F+I W + E++ S
Sbjct: 524 REVLQPTIVEKVSFLAWKEEFFDILD-EWKRIMGENNHS 561
[129][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 129 bits (325), Expect = 8e-29
Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
GNLK PWS++ + E I L ++N + +TINSQP VN +S+ GWG GY
Sbjct: 407 GNLKCLPWSDIT-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGY 465
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVFPA 120
VYQK YLEF K KL L++ K +TY A++ + +SN S NAVTWG+FP
Sbjct: 466 VYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPG 525
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
+E++QPTIV+ SF WK+E + I + N+ D P
Sbjct: 526 REILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKP 563
[130][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 129 bits (325), Expect = 8e-29
Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
GNLK PWS++ + E I L ++N + +TINSQP VN +S+ GWG GY
Sbjct: 218 GNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGY 276
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVFPA 120
VYQK YLEF K KL L++ K +TY A++ + +SN S NAVTWG+FP
Sbjct: 277 VYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPG 336
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
+E++QPTIV+ SF WK+E + I + N+ D P
Sbjct: 337 REILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKP 374
[131][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 129 bits (325), Expect = 8e-29
Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
GNLK PWS++ + E I L ++N + +TINSQP VN +S+ GWG GY
Sbjct: 407 GNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGY 465
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVFPA 120
VYQK YLEF K KL L++ K +TY A++ + +SN S NAVTWG+FP
Sbjct: 466 VYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPG 525
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
+E++QPTIV+ SF WK+E + I + N+ D P
Sbjct: 526 REILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKP 563
[132][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 129 bits (325), Expect = 8e-29
Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
GNLK PWS++ + E I L ++N + +TINSQP VN +S+ GWG GY
Sbjct: 407 GNLKCLPWSDIP-INDEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGY 465
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-TGESDVNAVTWGVFPA 120
VYQK YLEF K KL L++ K +TY A++ + +SN S NAVTWG+FP
Sbjct: 466 VYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPG 525
Query: 119 KEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
+E++QPTIV+ SF WK+E + I + N+ D P
Sbjct: 526 REILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKP 563
[133][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 129 bits (324), Expect = 1e-28
Identities = 68/169 (40%), Positives = 98/169 (57%), Gaps = 5/169 (2%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + G + PW++ L PET +I E+L ++N G+ ++ SQP+ NA KS GW
Sbjct: 433 FIDYLSGKIDVIPWAD-QALSPETALIQEELFQLNEKGWFSVASQPAANACKSTDNIFGW 491
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNT-GESDV---- 150
G G VYQKA++E F KD + L +A SITY A +K+ + D+
Sbjct: 492 GPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAKVPAGHDIKLTK 551
Query: 149 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
NAVTWGVFP+KEV+QPT++D SFK W +E+F +W W+ Y ++ S
Sbjct: 552 NAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLW-LEWSRCYKKNSKS 599
[134][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 129 bits (324), Expect = 1e-28
Identities = 67/169 (39%), Positives = 98/169 (57%), Gaps = 5/169 (2%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + + S PW + L PET +I EQL ++NS G T+ SQP+V++ S +GW
Sbjct: 402 FIDYLSAKISSLPWVSTE-LSPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGW 460
Query: 314 GGPGGYVYQKAYLEFFCSK---DKLDTLVEKSKAFPSITYMAVNKSENWVSNT--GESDV 150
G G ++QK+++EFF K ++L L++K + +ITY N +N S
Sbjct: 461 GPRNGRIFQKSFVEFFVPKTEWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQR 520
Query: 149 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
A+TWGVFP+KEV+QPT++D SF+ W +EAF +W WA Y D PS
Sbjct: 521 TAITWGVFPSKEVLQPTVIDRQSFQAWNEEAFGLW-LDWARCYAPDSPS 568
[135][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 129 bits (324), Expect = 1e-28
Identities = 67/158 (42%), Positives = 89/158 (56%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L PWS+ + E I L +N G TINSQP+VN KS P GWG GY
Sbjct: 395 GKLARLPWSDTP-ITTEANAIKTSLIDLNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGY 453
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
VYQKAYLE +D L+ + + +TY AV+K+ +NT +S NA+TWG+F +
Sbjct: 454 VYQKAYLELLVPPYLIDELIARIEKNGDLTYHAVSKTGELRTNTRDSP-NALTWGIFAGR 512
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++QPTIV+ SF WKDEA+ + WA + PS
Sbjct: 513 EIVQPTIVETVSFLAWKDEAYRL-GDDWAKCHDTSSPS 549
[136][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 128 bits (321), Expect = 2e-28
Identities = 65/163 (39%), Positives = 94/163 (57%), Gaps = 5/163 (3%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW++ L PET +I E+L ++N G+ ++ SQP+VN KS GWG G
Sbjct: 446 GKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFGWGPRNGI 504
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-----TGESDVNAVTWG 132
+YQK+++E F K+ L+ K + ++TY NK SN + NAVTWG
Sbjct: 505 IYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLSKNAVTWG 564
Query: 131 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S
Sbjct: 565 VFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKS 606
[137][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 128 bits (321), Expect = 2e-28
Identities = 65/163 (39%), Positives = 94/163 (57%), Gaps = 5/163 (3%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW++ L PET +I E+L ++N G+ ++ SQP+VN KS GWG G
Sbjct: 446 GKVDVVPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAVNGCKSTDNIFGWGPRNGI 504
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-----TGESDVNAVTWG 132
+YQK+++E F K+ L+ K + ++TY NK SN + NAVTWG
Sbjct: 505 IYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNKDGEIKSNLPIGPNVKLSKNAVTWG 564
Query: 131 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S
Sbjct: 565 VFPSKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKS 606
[138][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 127 bits (320), Expect = 3e-28
Identities = 63/159 (39%), Positives = 97/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G++K+ PWS+L GL ET I E+L ++N G+L++ SQP+ N ++S GWG G
Sbjct: 459 GSMKALPWSDL-GLSAETAFIQEELIELNQRGYLSLASQPATNGSQSTDNIFGWGPANGL 517
Query: 296 VYQKAYLEFFCSKDKLDTLVEK--SKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFP 123
+YQKA++E F K++ + +++ +Y + + + +N NAVTWGVFP
Sbjct: 518 IYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSYYLGDYTGYFETNLQPKSSNAVTWGVFP 577
Query: 122 AKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
EV+Q TIV+ SFK W+DEAF IW W+ L+P++ P
Sbjct: 578 NSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTP 615
[139][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 127 bits (319), Expect = 4e-28
Identities = 56/116 (48%), Positives = 75/116 (64%), Gaps = 1/116 (0%)
Frame = -1
Query: 347 AAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP-SITYMAVNKSENWVS 171
A S P +GWG GGYV+QKAYLEFF S++ ++ L++ K + + Y V+ ++
Sbjct: 1 AKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENIT 60
Query: 170 NTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
N E NAVTWG+FP +E+IQPT+VDP SF WKDEAF +W W LY E+ PS
Sbjct: 61 NAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPS 116
[140][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 126 bits (316), Expect = 9e-28
Identities = 67/160 (41%), Positives = 93/160 (58%), Gaps = 5/160 (3%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G++ + PW +L GL PET +I E+L ++N GFLT+ SQP+ N + S + GWG G
Sbjct: 458 GSIDALPWCDL-GLSPETALIQEELIQLNERGFLTLASQPATNGSPSTNKIFGWGPAYGV 516
Query: 296 VYQKAYLEFFCSKD-----KLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWG 132
VYQKA++E F K+ + +E+ +TY A + N+ +N + N VTWG
Sbjct: 517 VYQKAFIEMFVPKNIWENGNMKKAIEQ-YGRAKLTYYANDSQGNFETNLESNSSNVVTWG 575
Query: 131 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
VF +VIQ TIV SFK W DEAF IW WA L+P +
Sbjct: 576 VFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEWAKLFPRN 614
[141][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 126 bits (316), Expect = 9e-28
Identities = 63/163 (38%), Positives = 94/163 (57%), Gaps = 5/163 (3%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW++ L PET +I E+L ++N G+ ++ SQP++N KS GWG G
Sbjct: 446 GKVDVIPWAD-SSLSPETALIQEELFQLNEKGWFSVASQPAINGCKSTDNIFGWGPRNGT 504
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN-----TGESDVNAVTWG 132
+YQK+++E F K+ L+ K + ++TY +K SN + NAVTWG
Sbjct: 505 IYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDKDGEIRSNLPIGPNAKLSKNAVTWG 564
Query: 131 VFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VFP+KEV+QPT++D SFK W +EAF +W WA Y ++ S
Sbjct: 565 VFPSKEVVQPTVIDYESFKAWNEEAFLLWV-EWARCYKKNSKS 606
[142][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 124 bits (311), Expect = 3e-27
Identities = 67/145 (46%), Positives = 85/145 (58%), Gaps = 2/145 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G LK PWS++ L E I + L +N + TINSQP VN S P +GWG GY
Sbjct: 409 GKLKCLPWSDVP-LNHEVDDILKHLIDLNKHHIFTINSQPKVNGKPSTDPVVGWGPTKGY 467
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVNKSENWVSNTGE-SDVNAVTWGVFP 123
VYQK YLEF ++KL E + +TY A++ +N +N E S NAVTWGVFP
Sbjct: 468 VYQKEYLEFLLPREKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDSRANAVTWGVFP 527
Query: 122 AKEVIQPTIVDPASFKVWKDEAFEI 48
E++QPTIV+ ASF WK+E F I
Sbjct: 528 GSEILQPTIVEKASFLAWKEEFFTI 552
[143][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 124 bits (311), Expect = 3e-27
Identities = 66/159 (41%), Positives = 93/159 (58%), Gaps = 4/159 (2%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE +GL ET I +QL +N G+ T+ SQP+VN KS GWG G+
Sbjct: 471 GQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGPKNGF 529
Query: 296 VYQKAYLEFFCSKDKLDTLVEK--SKAF-PSITYMAVNKSENWV-SNTGESDVNAVTWGV 129
V+QKA++E F + L K S A ++++ A N +++ S+ NAVTWG
Sbjct: 530 VFQKAFVELFLPTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGSTNAVTWGA 589
Query: 128 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
FP KE+I PTI++ SF+ W +EAF IW WA +Y +D
Sbjct: 590 FPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKD 627
[144][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri NRRL
181 RepID=A1CZX0_NEOFI
Length = 716
Score = 124 bits (311), Expect = 3e-27
Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 23/187 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKS 336
F+ G+L PWSE GL ET++I +L K I+S G+ T+ SQP+VN +S
Sbjct: 484 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRS 543
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN 168
D P GWG PG G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 544 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESS 603
Query: 167 T------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +
Sbjct: 604 LPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRV 662
Query: 23 YPEDDPS 3
YP P+
Sbjct: 663 YPRGTPT 669
[145][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 124 bits (310), Expect = 4e-27
Identities = 64/164 (39%), Positives = 95/164 (57%), Gaps = 12/164 (7%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE +GL PET II EQL ++N+ G+ T+ SQP+VN S GWG G+
Sbjct: 470 GELSAIPWSE-EGLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGF 528
Query: 296 VYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSNTGE---------SD 153
V+QKA++E F L E+ + ++ + A N + ++ ++ +
Sbjct: 529 VFQKAFVELFLPAADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPAS 588
Query: 152 VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
NAVTWGVFP KE+I PTI++ SF+ W +EAF+IW W+ +Y
Sbjct: 589 TNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVY 631
[146][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 124 bits (310), Expect = 4e-27
Identities = 64/161 (39%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+ + PWS+L GL ET +I E+L ++N G+LT+ SQP+ NA S GWG G
Sbjct: 464 GSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGR 522
Query: 296 VYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 126
+YQKA++E F + + +T ++ +Y A + S ++ +N + VTWGVF
Sbjct: 523 LYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVF 582
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P V Q TI++ SFK W+DEAF IWS WA L+P + P+
Sbjct: 583 PNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPA 622
[147][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 124 bits (310), Expect = 4e-27
Identities = 64/161 (39%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+ + PWS+L GL ET +I E+L ++N G+LT+ SQP+ NA S GWG G
Sbjct: 464 GSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGR 522
Query: 296 VYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 126
+YQKA++E F + + +T ++ +Y A + S ++ +N + VTWGVF
Sbjct: 523 LYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVF 582
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P V Q TI++ SFK W+DEAF IWS WA L+P + P+
Sbjct: 583 PNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPA 622
[148][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 124 bits (310), Expect = 4e-27
Identities = 64/161 (39%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+ + PWS+L GL ET +I E+L ++N G+LT+ SQP+ NA S GWG G
Sbjct: 464 GSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGR 522
Query: 296 VYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 126
+YQKA++E F + + +T ++ +Y A + S ++ +N + VTWGVF
Sbjct: 523 LYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVF 582
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P V Q TI++ SFK W+DEAF IWS WA L+P + P+
Sbjct: 583 PNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPA 622
[149][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 124 bits (310), Expect = 4e-27
Identities = 65/159 (40%), Positives = 92/159 (57%), Gaps = 4/159 (2%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE +GL ET I +QL +N G+ T+ SQP+VN KS GWG G+
Sbjct: 471 GQLTAIPWSE-EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGF 529
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWV-SNTGESDVNAVTWGV 129
V+QKA++E F TL K + ++++ A N +++ S+ NAVTWG
Sbjct: 530 VFQKAFVELFIPVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTWGA 589
Query: 128 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
FP KE+I PTI++ SF+ W +EAF IW WA +Y +D
Sbjct: 590 FPGKEIITPTIIEEVSFRAWAEEAFGIWG-EWARVYGKD 627
[150][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 124 bits (310), Expect = 4e-27
Identities = 64/161 (39%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G+ + PWS+L GL ET +I E+L ++N G+LT+ SQP+ NA S GWG G
Sbjct: 464 GSTDAIPWSDL-GLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGR 522
Query: 296 VYQKAYLEFFCSKDKLDTLVEKS---KAFPSITYMAVNKSENWVSNTGESDVNAVTWGVF 126
+YQKA++E F + + +T ++ +Y A + S ++ +N + VTWGVF
Sbjct: 523 LYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVF 582
Query: 125 PAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
P V Q TI++ SFK W+DEAF IWS WA L+P + P+
Sbjct: 583 PNSPVKQTTIIEEESFKAWRDEAFSIWS-EWAKLFPRNTPA 622
[151][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 123 bits (309), Expect = 6e-27
Identities = 65/154 (42%), Positives = 92/154 (59%), Gaps = 2/154 (1%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PWSEL GL PET +I E+L ++N TI+SQPS N KS GWG GYVYQKA+
Sbjct: 411 PWSEL-GLNPETGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVYQKAF 469
Query: 278 LEFFCSKDKL-DTLVEKSKAFPSITYMAVNKSENWVSNTG-ESDVNAVTWGVFPAKEVIQ 105
+E F +K + + ++ + S+T+ + + + +N N+VTWG FP KE++Q
Sbjct: 470 VEVFINKKQWNEEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFPDKEIVQ 529
Query: 104 PTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
TI+ SF+ W +EAF IW R W LYP++ S
Sbjct: 530 TTIIGEESFQAWNEEAFNIW-REWQKLYPKNTAS 562
[152][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 123 bits (308), Expect = 7e-27
Identities = 75/200 (37%), Positives = 102/200 (51%), Gaps = 36/200 (18%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGFLTINSQPSVNAAKS 336
F++ G L + PWSE GL PET I L I G+ TI SQP+V+ +S
Sbjct: 463 FRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRS 522
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENWVS 171
D P GWG PG G+V+QKA++EFFCSKD L L+++ + A N + ++ S
Sbjct: 523 DHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFES 581
Query: 170 NTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKD 63
+T S VNAVTWGVF KE+I PTI++ SF+ W +
Sbjct: 582 STSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGE 641
Query: 62 EAFEIWSRSWANLYPEDDPS 3
EAF IW W ++P P+
Sbjct: 642 EAFRIWD-EWRRIFPRGSPT 660
[153][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 123 bits (308), Expect = 7e-27
Identities = 73/185 (39%), Positives = 102/185 (55%), Gaps = 24/185 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGFLTINSQPSVNAAKS 336
F+ G L PWSE +GL ET II E L I+ G+ T+ SQP++N +S
Sbjct: 466 FRRHVSGELHMVPWSEGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRS 525
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFC-SKDKLDTL--VEKSKAFPSITYMAVNKSENWVS- 171
D P GWG PG G+V+QK ++EFFC +KD L L + + + + A N ++ S
Sbjct: 526 DDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESS 585
Query: 170 ----NTGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 27
NT + D VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W
Sbjct: 586 LPGPNTDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRR 644
Query: 26 LYPED 12
+YP++
Sbjct: 645 IYPKN 649
[154][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 122 bits (307), Expect = 1e-26
Identities = 68/177 (38%), Positives = 101/177 (57%), Gaps = 25/177 (14%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE +G ET+ I + L ++NS G+ ++ SQP+VN +SD GWG G+
Sbjct: 468 GELSAIPWSE-EGFNDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGPENGF 526
Query: 296 VYQKAYLEFFC-SKD--KLDTLVEKSKAFPSITYMAVNKSENWVS--------------- 171
V+QKA++EFF S D L+ +++ ++ + A N + ++VS
Sbjct: 527 VFQKAFVEFFIPSADWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMAAEAE 586
Query: 170 NTGESD-------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
T E+D NAVTWGVFP KE++ PTI++ SF+ W +EAF IWS WA +Y
Sbjct: 587 GTAEADHRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWS-EWAKIY 642
[155][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 122 bits (306), Expect = 1e-26
Identities = 64/165 (38%), Positives = 97/165 (58%), Gaps = 13/165 (7%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKIN----------SNGFLTINSQPSVNAAKSDSPAIGWGG 309
PW + L ET I + L +N G+ ++ SQP+V+ A S P +G+G
Sbjct: 489 PWCDAP-LMNETLQIRDHLLTLNRLAENASQSAGKGWWSVGSQPAVDGAPSTDPIVGFGP 547
Query: 308 PGGYVYQKAYLEFFCS---KDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVT 138
PGG+V+QK+++E F S KD+L ++ A ITY A N ++ SN G+ + N VT
Sbjct: 548 PGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSNLGDEEANTVT 607
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
W VFP KE++Q TI++ SF+ W++EAFEIW+ W+ L+P+ S
Sbjct: 608 WAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EWSLLFPKKSAS 651
[156][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 122 bits (306), Expect = 1e-26
Identities = 70/187 (37%), Positives = 100/187 (53%), Gaps = 23/187 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGFLTINSQPSVNAAKS 336
F+ G L PWSE GL PET+ I E L I+ G+ T+ SQP+VN +S
Sbjct: 465 FRRHVSGELHMVPWSEGGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVRS 524
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN 168
D P GWG P G+V+QK ++EFFC T ++ + + + A N + ++ S+
Sbjct: 525 DDPIFGWGPPREGFVFQKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFESS 584
Query: 167 ----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
T ++D VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W +
Sbjct: 585 LPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRI 643
Query: 23 YPEDDPS 3
YP P+
Sbjct: 644 YPRGSPT 650
[157][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 122 bits (306), Expect = 1e-26
Identities = 67/165 (40%), Positives = 94/165 (56%), Gaps = 13/165 (7%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE + L E+ I L ++N G+ T+ SQP+VN +S GWG P G+
Sbjct: 473 GQLSAIPWSE-EELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGF 531
Query: 296 VYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSN------TGES---- 156
V+QK+++EFF + L EK S+ S+ + A N ++VS+ G S
Sbjct: 532 VFQKSFVEFFIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSGAGP 591
Query: 155 DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
NAVTWGVFP KE+I PTI++ SF+ W +EAF IW WA +Y
Sbjct: 592 STNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVY 635
[158][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 122 bits (306), Expect = 1e-26
Identities = 74/200 (37%), Positives = 102/200 (51%), Gaps = 36/200 (18%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGFLTINSQPSVNAAKS 336
F++ G L + PWSE GL PET I L I G+ T+ SQP+V+ +S
Sbjct: 463 FRQHVSGGLHAVPWSEGGAAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRS 522
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDK----LDTLVEKSKAFPSITYMAVNKSENWVS 171
D P GWG PG G+V+QKA++EFFCSKD L L+++ + A N + ++ S
Sbjct: 523 DHPIFGWGPPGEGFVFQKAFVEFFCSKDDYRSHLKPLLQRY-GHDEFAWFATNAAGDFES 581
Query: 170 NTGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKD 63
+T S VNAVTWGVF KE+I PTI++ SF+ W +
Sbjct: 582 STSSSIPVPTGPVDAVFDDMDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGE 641
Query: 62 EAFEIWSRSWANLYPEDDPS 3
EAF IW W ++P P+
Sbjct: 642 EAFRIWD-EWRRIFPRGSPT 660
[159][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 122 bits (306), Expect = 1e-26
Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 9/167 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW + L ET +I E+L ++N G+ ++ SQPSVN A+S GWG G+
Sbjct: 445 GKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFGWGPSNGF 503
Query: 296 VYQKAYLEFFCSKDKLDT-LVEKSKAF---PSITYMAVNKSENWVSN-----TGESDVNA 144
V+QK+++E F K++ T L K K ITY A + S SN + NA
Sbjct: 504 VFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPDSHNSKNA 563
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VTWGVFP++EV+QPTI+D SF+ W +EAF +WS WA Y ++ S
Sbjct: 564 VTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWS-EWARCYKKNSVS 609
[160][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 122 bits (305), Expect = 2e-26
Identities = 69/187 (36%), Positives = 100/187 (53%), Gaps = 23/187 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKS 336
F+ G+L PWSE GL ET++I +L K I+ G+ T+ SQP+VN +S
Sbjct: 457 FRHHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN 168
D P GWG PG G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 167 T------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRV 635
Query: 23 YPEDDPS 3
YP P+
Sbjct: 636 YPRGTPT 642
[161][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 122 bits (305), Expect = 2e-26
Identities = 69/187 (36%), Positives = 100/187 (53%), Gaps = 23/187 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKS 336
F+ G+L PWSE GL ET++I +L K I+ G+ T+ SQP+VN +S
Sbjct: 457 FRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 516
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN 168
D P GWG PG G+V+QK ++EFFC T+++ A + + A N + S+
Sbjct: 517 DDPTFGWGPPGEGFVFQKPFVEFFCPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESS 576
Query: 167 T------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
++VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W +
Sbjct: 577 LPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRV 635
Query: 23 YPEDDPS 3
YP P+
Sbjct: 636 YPRGTPT 642
[162][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 121 bits (304), Expect = 2e-26
Identities = 66/161 (40%), Positives = 91/161 (56%), Gaps = 9/161 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + S PW + L PET +I E+L ++N+ G+ ++ SQP+VN S GWG G
Sbjct: 443 GKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFGWGPGNGI 501
Query: 296 VYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDVNA 144
+YQKA++E F KD KL ++K +ITY + SN + NA
Sbjct: 502 IYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQEHYNSKNA 561
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
+TWGVFP+KEV+QPTI+D SFK W +EAF +W WA Y
Sbjct: 562 ITWGVFPSKEVLQPTIIDLESFKAWNEEAFILW-LEWARCY 601
[163][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 121 bits (303), Expect = 3e-26
Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 1/144 (0%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G +K PWS+ L E I + L +N +TINSQP +N +S+ GWG GY
Sbjct: 407 GQIKCLPWSDTS-LDEEIDPILDHLLDLNRKMIITINSQPQINGIRSNHKVHGWGPKDGY 465
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVTWGVFPA 120
VYQK YLEF +K++ L ++ +TY AV+ +N SN + S NAVTWG+FP
Sbjct: 466 VYQKQYLEFLLPNEKVEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANAVTWGIFPG 525
Query: 119 KEVIQPTIVDPASFKVWKDEAFEI 48
+EV+QPTIV+ SF WK+E + I
Sbjct: 526 REVLQPTIVEKVSFLAWKEEFYRI 549
[164][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 121 bits (303), Expect = 3e-26
Identities = 67/183 (36%), Positives = 98/183 (53%), Gaps = 23/183 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGFLTINSQPSVNAAKS 336
F+ G+L PWSE GL ET+ I E L I+ G+ T+ SQP+VN +S
Sbjct: 453 FRRHVSGDLHMVPWSEGGAEENTSGLNAETETIRPELLALIDKKGWWTLASQPAVNGVRS 512
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN 168
D P GWG PG G+V+QK ++EFFC T ++ + + + A N + ++ S+
Sbjct: 513 DDPIFGWGPPGEGFVFQKPFVEFFCPASDFKTTLKPLLQKHGHEKLAWFATNAAGDFESS 572
Query: 167 T------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
++VNAVTWGVF KE++ PTI++ SF+ W DEA+ IW W +
Sbjct: 573 LPAETSDTEPVEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRI 631
Query: 23 YPE 15
YP+
Sbjct: 632 YPK 634
[165][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 120 bits (302), Expect = 4e-26
Identities = 66/161 (40%), Positives = 90/161 (55%), Gaps = 9/161 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + S PW + L PET +I E+L ++N+ G+ ++ SQP+VN S GWG G
Sbjct: 443 GKIDSLPWVDA-ALSPETALIQEELFEVNNKGWFSLASQPAVNGCLSSDKIFGWGPGNGI 501
Query: 296 VYQKAYLEFFCSKD----KLDTLVEKSKAFPSITYMAVNKSENWVSNTG-----ESDVNA 144
+YQKA++E F KD KL ++K +ITY + SN + NA
Sbjct: 502 IYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGDAEGRLTSNLNIDQEHYNSKNA 561
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
+TWGVFP KEV+QPTI+D SFK W +EAF +W WA Y
Sbjct: 562 ITWGVFPLKEVLQPTIIDLESFKAWNEEAFILW-LEWARCY 601
[166][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces dermatitidis
RepID=C5GI01_AJEDR
Length = 713
Score = 120 bits (302), Expect = 4e-26
Identities = 69/198 (34%), Positives = 105/198 (53%), Gaps = 34/198 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSD 333
F+ G+L PWSE GL ET I ++L + IN G+ T+ SQP+VN ++D
Sbjct: 462 FQRHVSGDLHIVPWSEGGTQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT 165
P GWG G G+V+QKA++EFFC+ L T+++ ++ + + A N + ++ S++
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSS 581
Query: 164 GESD------------------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 57
+D VNAVTWGVF KE++ PTI++ SF+ W DEA
Sbjct: 582 PPTDDSANDYSGPVDVYLDSNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEA 641
Query: 56 FEIWSRSWANLYPEDDPS 3
F IW W ++P P+
Sbjct: 642 FRIWD-EWRRVFPRGSPT 658
[167][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 120 bits (302), Expect = 4e-26
Identities = 68/160 (42%), Positives = 90/160 (56%), Gaps = 10/160 (6%)
Frame = -1
Query: 476 GNLKSSPWS------ELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
G LK PWS E+D + PE +N++L +TINSQP +N KS P GW
Sbjct: 406 GELKYLPWSDTSLNHEVDDILPELVTLNQKL-------IITINSQPQLNGVKSSHPVHGW 458
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE-SDVNAVT 138
G GYVYQK YLEF K+KL L + +TY AV+ + N +N + + NAVT
Sbjct: 459 GPRDGYVYQKMYLEFLLPKEKLSKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTRANAVT 518
Query: 137 WGVFPAKEVIQPTIVDPASFKVWKDEAFEI---WSRSWAN 27
WG+FP +EV+QPTIV+ SF WK E + I W ++ N
Sbjct: 519 WGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEWKLNFIN 558
[168][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 120 bits (302), Expect = 4e-26
Identities = 68/182 (37%), Positives = 100/182 (54%), Gaps = 23/182 (12%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKS 336
F+ G L PWSE GL ET++I +L K I+ G+ T+ SQP+VN +S
Sbjct: 458 FRRHVSGELYIVPWSEGGAEENTSGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRS 517
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSN 168
D+ GWG PG G+V+QK ++EFFC +T+++ + + + A N + S+
Sbjct: 518 DNSTFGWGPPGEGFVFQKPFVEFFCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSS 577
Query: 167 ----TGESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANL 24
T +SD VNAVTWGVF KE++ PTI++ SF+ W +EA+ IW W +
Sbjct: 578 LPAETADSDALEPNPDNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWRRI 636
Query: 23 YP 18
YP
Sbjct: 637 YP 638
[169][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 120 bits (301), Expect = 5e-26
Identities = 61/158 (38%), Positives = 88/158 (55%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L++ PWSE + ET I +QL +NS G+ T+ SQP+VN +S P GWG G+
Sbjct: 472 GELQTIPWSE-ESFSAETDKIRDQLVALNSKGWWTLASQPAVNGLRSSDPTFGWGPQNGF 530
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAK 117
V+QKA++EFF L ++ +N+ E E+ NAV+WGVFP K
Sbjct: 531 VFQKAFVEFFLPLADWAALEKR-----------LNRPEMEGRREREASTNAVSWGVFPGK 579
Query: 116 EVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
E++ PTI++ SF+ W +EAF IW W +Y + S
Sbjct: 580 EIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSES 616
[170][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 119 bits (299), Expect = 8e-26
Identities = 66/165 (40%), Positives = 94/165 (56%), Gaps = 10/165 (6%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW++ L ET +I E+L +N G+ ++ SQP+VN KS GWG G
Sbjct: 438 GKIDILPWTD-SSLSAETTLIQEELFDLNDRGWFSLASQPAVNGCKSTDRIFGWGPKNGI 496
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFP-----SITYMAVNKSENWVSNT-----GESDVN 147
VYQKA++E F K++ ++ + KS P +ITY + N SN + N
Sbjct: 497 VYQKAFVEIFVPKEQWESEL-KSSLKPHFEEKTITYYVGDAEGNIESNLFVGPDAHNSKN 555
Query: 146 AVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
A+TWGVFP+KEV+QPTI+D SFK W +EAF +W WA Y ++
Sbjct: 556 AITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWI-EWARCYKKN 599
[171][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 119 bits (298), Expect = 1e-25
Identities = 67/167 (40%), Positives = 94/167 (56%), Gaps = 9/167 (5%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G + PW + L ET +I E+L ++N G+ ++ SQPSVN A+S GWG G+
Sbjct: 445 GKINILPWVDAP-LSAETALIQEELFELNDKGWFSLASQPSVNGARSSDKIFGWGPSNGF 503
Query: 296 VYQKAYLEFFCSKDKLDT-LVEKSKAF---PSITYMAVNKSENWVSN-----TGESDVNA 144
V+QK+++E F K++ T L K K ITY A + S SN + NA
Sbjct: 504 VFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYAGDSSGKIQSNLPVGPDSHNSKNA 563
Query: 143 VTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VTWGVFP +EV+QPTI+D SF+ W +EAF +W WA Y ++ S
Sbjct: 564 VTWGVFPLQEVLQPTIIDIESFRAWNEEAFHLW-LEWARCYKKNSVS 609
[172][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 119 bits (298), Expect = 1e-25
Identities = 63/165 (38%), Positives = 93/165 (56%), Gaps = 13/165 (7%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE + L+ E+ I L ++N G+ T+ SQP+VN +S GWG P G+
Sbjct: 471 GELSAIPWSE-EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGF 529
Query: 296 VYQKAYLEFFCSKDKLDTLVEK---SKAFPSITYMAVNKSENWVSN----------TGES 156
V+QK+++EFF ++ + L K S+ + + A N ++VS+
Sbjct: 530 VFQKSFVEFFIPANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASP 589
Query: 155 DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 21
NAVTWGVFP KE+I PTI++ SF+ W +EAF IW WA +Y
Sbjct: 590 STNAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVY 633
[173][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 119 bits (298), Expect = 1e-25
Identities = 73/179 (40%), Positives = 100/179 (55%), Gaps = 24/179 (13%)
Frame = -1
Query: 476 GNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGFLTINSQPSVNAAKSDSPAIG 318
G L PWSE GL ET++I E L I+ NG+ T+ SQP+VN +SD P G
Sbjct: 463 GELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYG 522
Query: 317 WGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENWVSN----T 165
WG P G+V+QK ++EFFC SKD L L++K + + A N ++ S+ T
Sbjct: 523 WGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQT 581
Query: 164 GESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
++D VN VTWGVF KE++ PTI++ SF+ W DEAF IW W +YP +
Sbjct: 582 SDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRN 639
[174][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 119 bits (298), Expect = 1e-25
Identities = 73/179 (40%), Positives = 100/179 (55%), Gaps = 24/179 (13%)
Frame = -1
Query: 476 GNLKSSPWSE------LDGLQPETKIIN-EQLGKINSNGFLTINSQPSVNAAKSDSPAIG 318
G L PWSE GL ET++I E L I+ NG+ T+ SQP+VN +SD P G
Sbjct: 511 GELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYG 570
Query: 317 WGGPG-GYVYQKAYLEFFC-SKDK---LDTLVEKSKAFPSITYMAVNKSENWVSN----T 165
WG P G+V+QK ++EFFC SKD L L++K + + A N ++ S+ T
Sbjct: 571 WGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKH-GHEKLAWFAANVKGDFESSLPAQT 629
Query: 164 GESD--------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
++D VN VTWGVF KE++ PTI++ SF+ W DEAF IW W +YP +
Sbjct: 630 SDADPIEMNPNNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRN 687
[175][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 119 bits (298), Expect = 1e-25
Identities = 66/181 (36%), Positives = 95/181 (52%), Gaps = 23/181 (12%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGY 297
G L + PWSE + ET+ I + L +NS G+ T+ SQP+VN +S+ GWG G+
Sbjct: 451 GALPAIPWSE-EEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGF 509
Query: 296 VYQKAYLEFFCSKDKLDTLVEKSKAFPSIT-YMAVNKSENWVSNTGESDV---------- 150
V+QKA++E F L EK + + + A N ++ S+ G D
Sbjct: 510 VFQKAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGNGF 569
Query: 149 ------------NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
NAVTWGVFP KE++ PTI++ SF+ W +EAF IW+ WA +Y +D P
Sbjct: 570 ADEQPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWA-EWAKVYGKDSP 628
Query: 5 S 3
S
Sbjct: 629 S 629
[176][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 118 bits (296), Expect = 2e-25
Identities = 72/188 (38%), Positives = 100/188 (53%), Gaps = 30/188 (15%)
Frame = -1
Query: 476 GNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSDSPAIG 318
G L PWSE GL ET I E+L + I+ G+ T+ SQP+VN +SD P G
Sbjct: 471 GELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFG 530
Query: 317 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------ 168
WG G G+V+QKA++EFFCS + +++ K +++ A N S ++ S+
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGI 590
Query: 167 TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 27
TG D VNAVTWGVF KE+I PTI++ SF+ W DEAF IW W
Sbjct: 591 TGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWD-EWRR 649
Query: 26 LYPEDDPS 3
++ P+
Sbjct: 650 IFRRGSPT 657
[177][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 118 bits (296), Expect = 2e-25
Identities = 67/198 (33%), Positives = 103/198 (52%), Gaps = 34/198 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSD 333
F+ G L PWSE GL ET I ++L + IN G+ T+ SQP+VN ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT 165
P GWG G G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 581
Query: 164 ------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 57
G + V AVTWGVF KE++ PTI++ SF+ W DEA
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEA 641
Query: 56 FEIWSRSWANLYPEDDPS 3
F IW W ++P P+
Sbjct: 642 FRIWD-EWRRIFPRGSPT 658
[178][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 118 bits (295), Expect = 2e-25
Identities = 67/198 (33%), Positives = 103/198 (52%), Gaps = 34/198 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSD 333
F+ G L PWSE GL ET I ++L + IN G+ T+ SQP+VN ++D
Sbjct: 462 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRND 521
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT 165
P GWG G G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 522 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSS 581
Query: 164 ------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 57
G + V AVTWGVF KE++ PTI++ SF+ W DEA
Sbjct: 582 PATDATTEDSSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEA 641
Query: 56 FEIWSRSWANLYPEDDPS 3
F IW W ++P P+
Sbjct: 642 FRIWD-EWRRIFPRGSPT 658
[179][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 118 bits (295), Expect = 2e-25
Identities = 70/199 (35%), Positives = 98/199 (49%), Gaps = 35/199 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE-----LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSD 333
F+ L G L + PWSE GL PET I +L K + G+ T+ SQPSVN ++D
Sbjct: 423 FRRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWWTLASQPSVNGVRND 482
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT 165
P GWG G G+V+QKA++EFFC D + ++ S + A+N ++ S+T
Sbjct: 483 HPIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFAWFAMNAKGDFQSST 542
Query: 164 G-------------------------ESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 60
VNAVTWGVF KE++ PTI++ SF+ W +E
Sbjct: 543 SPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEE 602
Query: 59 AFEIWSRSWANLYPEDDPS 3
AF IW W ++P S
Sbjct: 603 AFGIW-EEWRRIFPRGSAS 620
[180][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 118 bits (295), Expect = 2e-25
Identities = 67/198 (33%), Positives = 102/198 (51%), Gaps = 34/198 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE-----LDGLQPETKIINEQL-GKINSNGFLTINSQPSVNAAKSD 333
F+ G L PWSE GL ET I ++L IN G+ T+ SQP+VN ++D
Sbjct: 461 FQRHVSGELHLVPWSEGGAQDTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRND 520
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSNT 165
P GWG G G+V+QKA++EFFC +++++ +S + + A N + +++S++
Sbjct: 521 HPIFGWGPRGEGFVFQKAFVEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSS 580
Query: 164 ------------------------GESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEA 57
G + V AVTWGVF KE++ PTI++ SF+ W DEA
Sbjct: 581 PATDAATEDFSGPVDVFLDSNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEA 640
Query: 56 FEIWSRSWANLYPEDDPS 3
F IW W ++P P+
Sbjct: 641 FRIWD-EWRRIFPRGSPT 657
[181][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 117 bits (293), Expect = 4e-25
Identities = 60/152 (39%), Positives = 89/152 (58%), Gaps = 2/152 (1%)
Frame = -1
Query: 461 SPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKA 282
+P+S + L PE+ I L ++ G+ T+ SQP+V+ S GWG GYV+QK
Sbjct: 426 TPFSPTE-LCPESITILPHLERLTKRGWWTVGSQPAVDGISSSDETFGWGPRAGYVFQKG 484
Query: 281 YLEFFCSKDKLDTLVEKSKAFPS--ITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVI 108
++EFFC ++ + ++ K + + Y N + SN E NAVTWGVFP +E+
Sbjct: 485 FVEFFCDFHDVEAIEQRIKQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFPGQEIQ 544
Query: 107 QPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
Q TI++ SF WKDEA++IW+ SWA+LY D
Sbjct: 545 QTTIIEKESFLTWKDEAYDIWN-SWASLYHPD 575
[182][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 117 bits (293), Expect = 4e-25
Identities = 63/163 (38%), Positives = 92/163 (56%), Gaps = 6/163 (3%)
Frame = -1
Query: 476 GNLKSSPWSELDGLQPETKIINEQLGKINSNGFL-TINSQPSVNAAKSDSPAIGWGGPGG 300
G L+ PWS+ + E +I QL +N + TINSQP VN +S+ GWG G
Sbjct: 401 GELRCLPWSDTP-VSSEVDVIRRQLIALNEQQLIVTINSQPQVNGLRSNVKGFGWGPSDG 459
Query: 299 YVYQKAYLEFFCSKDKLDTLVEK----SKAFPSITYMAVNKSENWVSNTGE-SDVNAVTW 135
YVYQK YLEF + + + L ++ ++ S+TY+A + W SN + + AVTW
Sbjct: 460 YVYQKQYLEFLLPRARFERLQQELSKTNETTSSLTYLAADSHGGWWSNQPDGAKATAVTW 519
Query: 134 GVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDP 6
GVFP +EV+QPTIV+ SF W+DE + I + W +++ P
Sbjct: 520 GVFPGREVLQPTIVEKISFLAWRDEFYRI-LQDWRDIFVHASP 561
[183][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 116 bits (290), Expect = 9e-25
Identities = 67/189 (35%), Positives = 99/189 (52%), Gaps = 25/189 (13%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSEL------DGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKS 336
F+ G L PWSE +GL ET++I +L K I+ G+ T+ SQP+VN +
Sbjct: 456 FRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQPAVNGVHN 515
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVEKSKA---FPSITYMAVNKSENWVSN 168
D P GWG G+V+QK ++EFFCS + +++ A +T+ A N ++ S+
Sbjct: 516 DHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESS 575
Query: 167 --------------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWA 30
+ VNAVTWGVF KE++ PTI++ SF+ W +EAF IW W
Sbjct: 576 LPAQPADMDLDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWR 634
Query: 29 NLYPEDDPS 3
+YP P+
Sbjct: 635 RIYPRGSPT 643
[184][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 116 bits (290), Expect = 9e-25
Identities = 65/166 (39%), Positives = 93/166 (56%), Gaps = 5/166 (3%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGW 315
F + G + PW++ L PET +I E+L ++N G+ ++ SQP+VN +S+ GW
Sbjct: 425 FVDYLSGKIDVVPWADTS-LSPETALIQEELFELNQKGWFSVASQPAVNGCRSNDNVFGW 483
Query: 314 GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSN--TGESD---V 150
G G VYQK+++E F L K + + TY +KS + T ES
Sbjct: 484 GPGNGVVYQKSFVELFIPAKDWKEL--KPRLDDATTYYVGDKSGRIELSLFTNESTRHLK 541
Query: 149 NAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 12
NAVTWGVFP KEV+QPT++D SFK W +EAF +W WA Y ++
Sbjct: 542 NAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKN 586
[185][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 115 bits (289), Expect = 1e-24
Identities = 71/188 (37%), Positives = 99/188 (52%), Gaps = 30/188 (15%)
Frame = -1
Query: 476 GNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSDSPAIG 318
G L PWSE GL ET I E+L + I+ G+ T+ SQP+VN +SD P G
Sbjct: 471 GELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFG 530
Query: 317 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------ 168
WG G G+V+QKA++EFFCS + +++ K +++ A N S ++ S+
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGT 590
Query: 167 TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 27
TG D VNAVTWGVF KE+I PTI++ SF+ W EAF IW W
Sbjct: 591 TGLDDAVPDYNGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRR 649
Query: 26 LYPEDDPS 3
++ P+
Sbjct: 650 IFRRGSPT 657
[186][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 115 bits (289), Expect = 1e-24
Identities = 71/188 (37%), Positives = 99/188 (52%), Gaps = 30/188 (15%)
Frame = -1
Query: 476 GNLKSSPWSE------LDGLQPETKIINEQLGK-INSNGFLTINSQPSVNAAKSDSPAIG 318
G L PWSE GL ET I E+L + I+ G+ T+ SQP+VN +SD P G
Sbjct: 471 GELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFG 530
Query: 317 WGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN------ 168
WG G G+V+QKA++EFFCS + +++ K +++ A N S ++ S+
Sbjct: 531 WGPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGT 590
Query: 167 TGESD-------------VNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWAN 27
TG D VNAVTWGVF KE+I PTI++ SF+ W EAF IW W
Sbjct: 591 TGLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRR 649
Query: 26 LYPEDDPS 3
++ P+
Sbjct: 650 IFRRGSPT 657
[187][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JM22_UNCRE
Length = 709
Score = 112 bits (279), Expect = 2e-23
Identities = 68/199 (34%), Positives = 98/199 (49%), Gaps = 35/199 (17%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSE------LDGLQPETKIINEQL-GKINSNGFLTINSQPSVNAAKS 336
F+ G L + PWSE GL PET I L I+ G+ T+ SQP+VN +S
Sbjct: 461 FRRHVSGALHAVPWSEGGAAEESGGLNPETATIRPYLLDLIDKRGWWTLASQPAVNGVRS 520
Query: 335 DSPAIGWGGPG-GYVYQKAYLEFFCSKDKLDTLVE---KSKAFPSITYMAVNKSENWVSN 168
D GWG PG G+V+QKA++EFFCS + + ++ + + A N + ++ ++
Sbjct: 521 DDTTFGWGPPGEGFVFQKAFVEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFEAS 580
Query: 167 TGES------------------------DVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 60
T S VNAVTWGVF KE+I PTI++ SF+ W +E
Sbjct: 581 TPPSAHSPTEPVDAGFEDPSSPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEE 640
Query: 59 AFEIWSRSWANLYPEDDPS 3
AF IW W ++ P+
Sbjct: 641 AFRIWD-EWRRIFARGSPT 658
[188][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 111 bits (278), Expect = 2e-23
Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 4/143 (2%)
Frame = -1
Query: 437 LQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSK 258
L E+ +I L ++ + T+ SQP+V+ S +GWG GGYV+QK ++EFFC +
Sbjct: 418 LSSESLMILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEE 477
Query: 257 DKLDTLVEKSK--AFPSITYMAVNKSENWV--SNTGESDVNAVTWGVFPAKEVIQPTIVD 90
+D + + + + Y A N + SN E NAVTWGVFP +E+ Q TI++
Sbjct: 478 KDMDVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIE 537
Query: 89 PASFKVWKDEAFEIWSRSWANLY 21
SF WKDEAF IWS WA+ Y
Sbjct: 538 KESFLTWKDEAFSIWS-EWASFY 559
[189][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 107 bits (267), Expect = 4e-22
Identities = 66/162 (40%), Positives = 87/162 (53%), Gaps = 10/162 (6%)
Frame = -1
Query: 458 PWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAY 279
PW++ D L PET ++ +L K+N G LTINSQP+VN S P +GWG GYV+QKAY
Sbjct: 448 PWND-DPLAPETNLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAY 506
Query: 278 LEFFCSKDKLDTLVEKSKAF-PSITYMAVNKSENW-------VSNTGESDV--NAVTWGV 129
LEFF S + + L++ K + P + Y VN ++ S+TG V NA G
Sbjct: 507 LEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHKHTQLLKLLSSSDTGMGPVIQNAQDLGN 566
Query: 128 FPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPS 3
VI +I D DEAF +W WA LY E+ PS
Sbjct: 567 L---SVIWISITD--------DEAFALWIEQWAKLYEEESPS 597
[190][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 105 bits (263), Expect = 1e-21
Identities = 60/167 (35%), Positives = 91/167 (54%), Gaps = 8/167 (4%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDGLQPETKIINEQLGKINS------NGFLTINSQPSVNAAKSD 333
F G L PW ++ + ET + L +NS + T+ SQP+V+ S
Sbjct: 385 FSRFVDGRLACMPWCDIP-VWDETMQLLPALLHLNSPPSAGGKAWWTVGSQPAVDGCDST 443
Query: 332 SPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPS-ITYMAVN-KSENWVSNTGE 159
P G+G GGY++QKA++E F +++ + LV+ + + +TY A + +N
Sbjct: 444 DPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQGSSTPVTYFAGKCDPTTFETNLTT 503
Query: 158 SDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRSWANLYP 18
+ +N VTWGVFP EV Q TI++ ASF+ W+DEAF IW R W L+P
Sbjct: 504 NGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFP 549
[191][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 102 bits (255), Expect = 1e-20
Identities = 69/196 (35%), Positives = 92/196 (46%), Gaps = 37/196 (18%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDG-----LQPETKIINEQLGKI-NSNGFLTINSQPSVNAAKSD 333
F++ G L PWSE L ET+ I QL +I + T+ SQP+VN +SD
Sbjct: 467 FRKHVSGELYIVPWSEGGAAEDANLNAETETIKPQLLQIIEKKNWWTLASQPAVNGVRSD 526
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAF--------------- 219
P GWG PG G+V+QKA++EFFC +K K L S+ F
Sbjct: 527 HPVFGWGPPGEGFVFQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLESSF 586
Query: 218 ---------PSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK 66
P T AV ++ ES AVTWG F +E+ PTI++ SF+ W
Sbjct: 587 LISTSSSPKPEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWG 646
Query: 65 DEAFEIWSRSWANLYP 18
+EAF IW W +YP
Sbjct: 647 EEAFRIWD-EWRRIYP 661
[192][TOP]
>UniRef100_A7S359 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
RepID=A7S359_NEMVE
Length = 102
Score = 102 bits (254), Expect = 1e-20
Identities = 52/102 (50%), Positives = 68/102 (66%)
Frame = -1
Query: 464 SSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQK 285
S PW++ + L ET I E+L NSNG L+INSQPSVNAA S P +GWGG GGY+YQK
Sbjct: 3 SLPWND-EELALETSFIKEKLIHFNSNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQK 61
Query: 284 AYLEFFCSKDKLDTLVEKSKAFPSITYMAVNKSENWVSNTGE 159
AYLEFF S + + L+++ K +P + Y VN N + N G+
Sbjct: 62 AYLEFFASPEVVYILLQELKNYPQVNYHVVN---NHLRNLGK 100
[193][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 102 bits (254), Expect = 1e-20
Identities = 69/198 (34%), Positives = 96/198 (48%), Gaps = 39/198 (19%)
Frame = -1
Query: 494 FKELCIGNLKSSPWSELDG-----LQPETKIINEQLGKI-NSNGFLTINSQPSVNAAKSD 333
F++ G L PWSE L ET+II QL +I + T+ SQP+VN +SD
Sbjct: 465 FRKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSD 524
Query: 332 SPAIGWGGPG-GYVYQKAYLEFFC------SKDKLDTLVEKSKAFPSITYMAVNKSENWV 174
P GWG PG G+V+QKA++EFFC +K K L S+ F ++ A+N + +
Sbjct: 525 HPVFGWGPPGEGFVFQKAFVEFFCPNADYQNKVKPTLLKHGSEEF---SWFAINATGHLE 581
Query: 173 SN--------------------------TGESDVNAVTWGVFPAKEVIQPTIVDPASFKV 72
S+ ES AVTWG F +E+ PTI++ SF+
Sbjct: 582 SSFLLSASSSPKPEDASSTIAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRA 641
Query: 71 WKDEAFEIWSRSWANLYP 18
W +EAF IW W +YP
Sbjct: 642 WGEEAFRIWD-EWRRIYP 658
[194][TOP]
>UniRef100_UPI00016DFE38 UPI00016DFE38 related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016DFE38
Length = 514
Score = 68.2 bits (165), Expect = 3e-10
Identities = 32/69 (46%), Positives = 44/69 (63%)
Frame = -1
Query: 491 KELCIGNLKSSPWSELDGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWG 312
K LC+ PW++ + L ET ++ ++L K+N G LTINSQP++N S P +GWG
Sbjct: 453 KVLCL------PWND-EPLAQETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWG 505
Query: 311 GPGGYVYQK 285
GGYVYQK
Sbjct: 506 PAGGYVYQK 514