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[1][TOP]
>UniRef100_Q9C509 Sphingosine-1-phosphate lyase n=2 Tax=Arabidopsis thaliana
RepID=SGPL_ARATH
Length = 544
Score = 270 bits (691), Expect = 5e-71
Identities = 134/134 (100%), Positives = 134/134 (100%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL
Sbjct: 411 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 470
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG
Sbjct: 471 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 530
Query: 177 MVNELLVSFMDSQY 136
MVNELLVSFMDSQY
Sbjct: 531 MVNELLVSFMDSQY 544
[2][TOP]
>UniRef100_B9GZM5 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GZM5_POPTR
Length = 540
Score = 228 bits (581), Expect = 3e-58
Identities = 107/132 (81%), Positives = 122/132 (92%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+NT IME SKR+++G++EI ELF+IG+PDMTIVAFGS LDIFEVNDIMSSKGWHL
Sbjct: 407 GYLENTKAIMEVSKRIQKGIKEIPELFIIGRPDMTIVAFGSNDLDIFEVNDIMSSKGWHL 466
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNSIHICITLQH PVV+DFLRDL+E+V+TVK NPGPI GGLAPIYGAAGK+PDRG
Sbjct: 467 NALQRPNSIHICITLQHAPVVEDFLRDLKESVQTVKENPGPINGGLAPIYGAAGKIPDRG 526
Query: 177 MVNELLVSFMDS 142
MV ELLV++MDS
Sbjct: 527 MVQELLVNYMDS 538
[3][TOP]
>UniRef100_A7R367 Chromosome undetermined scaffold_488, whole genome shotgun sequence
n=1 Tax=Vitis vinifera RepID=A7R367_VITVI
Length = 537
Score = 220 bits (561), Expect = 6e-56
Identities = 102/132 (77%), Positives = 120/132 (90%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL NT + ME SK+L+ G+++I ELFVIG+PDMTIVAFGS +DIFEVNDI+SSKGWHL
Sbjct: 404 GYLNNTRETMEVSKKLQRGIKDIPELFVIGRPDMTIVAFGSNVVDIFEVNDILSSKGWHL 463
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNSIHIC+TLQHV +++DFL+DL+E+V+TVK NPGPI GGLAPIYGAAGKMPDRG
Sbjct: 464 NALQRPNSIHICLTLQHVTILEDFLKDLKESVQTVKQNPGPINGGLAPIYGAAGKMPDRG 523
Query: 177 MVNELLVSFMDS 142
MV ELLV+FMDS
Sbjct: 524 MVGELLVNFMDS 535
[4][TOP]
>UniRef100_B9RMB8 Sphingosine phosphate lyase, putative n=1 Tax=Ricinus communis
RepID=B9RMB8_RICCO
Length = 541
Score = 214 bits (545), Expect = 4e-54
Identities = 99/132 (75%), Positives = 118/132 (89%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+NT IME +K++++G+ E+ ELFVIG+PDMTIVAFGS LDIFEVNDI+SSKGWHL
Sbjct: 408 GYLKNTKVIMEVTKKIQKGIEEMPELFVIGRPDMTIVAFGSNVLDIFEVNDILSSKGWHL 467
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH V +DFL+DLRE+V+TVK NPGPI GGLAPIYGAAGK+PDR
Sbjct: 468 NALQRPNSLHICVTLQHASVYEDFLQDLRESVQTVKQNPGPINGGLAPIYGAAGKIPDRS 527
Query: 177 MVNELLVSFMDS 142
MV ELLV++MDS
Sbjct: 528 MVQELLVNYMDS 539
[5][TOP]
>UniRef100_UPI0000DD88F6 Os01g0100900 n=1 Tax=Oryza sativa Japonica Group
RepID=UPI0000DD88F6
Length = 537
Score = 212 bits (540), Expect = 2e-53
Identities = 96/132 (72%), Positives = 118/132 (89%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++NT IME SK+++ G+ +I LFVIGKPDMT+VAFGS ++DIFEVNDIMSSKGWHL
Sbjct: 404 GYMENTGHIMEVSKKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHL 463
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH + ++FL+DL+++V+TVKANPGPI+GG APIYGAAGKMPDRG
Sbjct: 464 NALQRPNSLHICVTLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRG 523
Query: 177 MVNELLVSFMDS 142
MV ELLV FMD+
Sbjct: 524 MVRELLVEFMDA 535
[6][TOP]
>UniRef100_C5XFN1 Putative uncharacterized protein Sb03g009170 n=1 Tax=Sorghum
bicolor RepID=C5XFN1_SORBI
Length = 533
Score = 212 bits (540), Expect = 2e-53
Identities = 99/132 (75%), Positives = 115/132 (87%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL NT +ME SK+++ G+ EI LFVIGKPDMTIVAFGS +DIFEVNDIMSSKGWHL
Sbjct: 400 GYLDNTRCVMEVSKKIQRGIGEIPGLFVIGKPDMTIVAFGSDVVDIFEVNDIMSSKGWHL 459
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH + D FL+DL+++V+TVKANPGPI+GG+APIYGAAGKMPDRG
Sbjct: 460 NALQRPNSLHICVTLQHTTIYDQFLKDLQDSVDTVKANPGPISGGMAPIYGAAGKMPDRG 519
Query: 177 MVNELLVSFMDS 142
V ELLV FMDS
Sbjct: 520 TVRELLVEFMDS 531
[7][TOP]
>UniRef100_B7FAK6 Os01g0100900 protein n=2 Tax=Oryza sativa RepID=B7FAK6_ORYSJ
Length = 539
Score = 212 bits (540), Expect = 2e-53
Identities = 96/132 (72%), Positives = 118/132 (89%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++NT IME SK+++ G+ +I LFVIGKPDMT+VAFGS ++DIFEVNDIMSSKGWHL
Sbjct: 406 GYMENTGHIMEVSKKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHL 465
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH + ++FL+DL+++V+TVKANPGPI+GG APIYGAAGKMPDRG
Sbjct: 466 NALQRPNSLHICVTLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRG 525
Query: 177 MVNELLVSFMDS 142
MV ELLV FMD+
Sbjct: 526 MVRELLVEFMDA 537
[8][TOP]
>UniRef100_Q52RG7 Sphingosine-1-phosphate lyase n=1 Tax=Oryza sativa Japonica Group
RepID=SGPL_ORYSJ
Length = 539
Score = 212 bits (540), Expect = 2e-53
Identities = 96/132 (72%), Positives = 118/132 (89%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++NT IME SK+++ G+ +I LFVIGKPDMT+VAFGS ++DIFEVNDIMSSKGWHL
Sbjct: 406 GYMENTGHIMEVSKKIQRGIEDIPGLFVIGKPDMTVVAFGSDSVDIFEVNDIMSSKGWHL 465
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH + ++FL+DL+++V+TVKANPGPI+GG APIYGAAGKMPDRG
Sbjct: 466 NALQRPNSLHICVTLQHTVIYEEFLKDLKDSVDTVKANPGPISGGRAPIYGAAGKMPDRG 525
Query: 177 MVNELLVSFMDS 142
MV ELLV FMD+
Sbjct: 526 MVRELLVEFMDA 537
[9][TOP]
>UniRef100_B6SZI2 Sphingosine-1-phosphate lyase n=1 Tax=Zea mays RepID=B6SZI2_MAIZE
Length = 533
Score = 211 bits (537), Expect = 4e-53
Identities = 99/132 (75%), Positives = 115/132 (87%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL +TS+IM+ SK+++ G+ EI LFVIGKPDMT+VAFGS +DIFEVNDIMSSKGWHL
Sbjct: 400 GYLDSTSRIMDVSKKIQRGIGEIPGLFVIGKPDMTVVAFGSDVVDIFEVNDIMSSKGWHL 459
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNS+HIC+TLQH V D FL+DL+++V TVKANPGPI+GG APIYGAAGKMPDRG
Sbjct: 460 NALQRPNSLHICVTLQHTTVYDQFLKDLQDSVNTVKANPGPISGGKAPIYGAAGKMPDRG 519
Query: 177 MVNELLVSFMDS 142
V ELLV FMDS
Sbjct: 520 TVRELLVEFMDS 531
[10][TOP]
>UniRef100_A5BC55 Putative uncharacterized protein n=1 Tax=Vitis vinifera
RepID=A5BC55_VITVI
Length = 133
Score = 208 bits (530), Expect = 2e-52
Identities = 96/122 (78%), Positives = 113/122 (92%)
Frame = -1
Query: 510 MEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSI 331
ME SK+L+ G+++I ELFVIG+PDMTIVAFGS +DIFEVNDI+SSKGWHLNALQRPNSI
Sbjct: 1 MEVSKKLQRGIKDIPELFVIGRPDMTIVAFGSNVVDIFEVNDILSSKGWHLNALQRPNSI 60
Query: 330 HICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRGMVNELLVSF 151
HIC+TLQHV +++DFL+DL+E+V+TVK NPGPI GGLAPIYGAAGKMPDRGMV ELLV+F
Sbjct: 61 HICLTLQHVTILEDFLKDLKESVQTVKQNPGPINGGLAPIYGAAGKMPDRGMVGELLVNF 120
Query: 150 MD 145
MD
Sbjct: 121 MD 122
[11][TOP]
>UniRef100_A9NUF1 Putative uncharacterized protein n=1 Tax=Picea sitchensis
RepID=A9NUF1_PICSI
Length = 544
Score = 189 bits (480), Expect = 1e-46
Identities = 81/132 (61%), Positives = 111/132 (84%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ K+ME SK +++G+++I ELF++G+PDMT++AFGS LDIF+VND++S++GWHL
Sbjct: 411 GYLEAVRKVMEVSKTIQQGIKQIPELFIVGRPDMTVIAFGSDKLDIFKVNDVLSTQGWHL 470
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
NALQRPNSIHIC+TLQH + +DFL+DL++AV TV+ NP G+APIYGAA KMPDRG
Sbjct: 471 NALQRPNSIHICLTLQHTLIAEDFLKDLKKAVTTVQENPSAFEDGMAPIYGAAAKMPDRG 530
Query: 177 MVNELLVSFMDS 142
MV +LL+ +MD+
Sbjct: 531 MVQDLLIEYMDN 542
[12][TOP]
>UniRef100_A9SKK9 Predicted protein n=1 Tax=Physcomitrella patens subsp. patens
RepID=A9SKK9_PHYPA
Length = 537
Score = 164 bits (416), Expect = 4e-39
Identities = 74/133 (55%), Positives = 103/133 (77%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY Q T K+MEA++ ++ G+ +I L+V+GKPDMT+VAF SK L+I++VN+ M+ KGW
Sbjct: 403 SGYTQITRKLMEAARNIKLGIPDIEGLYVLGKPDMTVVAFASKELNIYKVNEAMAEKGWS 462
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDR 181
LNAL +P+S+HIC+TLQHV VVD FL DL+ AV+ V+ NPG G+APIYGA +PDR
Sbjct: 463 LNALHKPSSVHICVTLQHVDVVDKFLDDLKAAVKYVRDNPGKYEDGMAPIYGAGATLPDR 522
Query: 180 GMVNELLVSFMDS 142
G + ++LV +MDS
Sbjct: 523 GTIRDILVDYMDS 535
[13][TOP]
>UniRef100_B9GMN2 Predicted protein n=1 Tax=Populus trichocarpa RepID=B9GMN2_POPTR
Length = 107
Score = 163 bits (412), Expect = 1e-38
Identities = 84/123 (68%), Positives = 96/123 (78%)
Frame = -1
Query: 510 MEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSI 331
ME SKR+++G PDMTIVA S LDIFEVNDIM+SKGWHLNALQRPNSI
Sbjct: 1 MEVSKRIQKG------------PDMTIVAIRSNDLDIFEVNDIMASKGWHLNALQRPNSI 48
Query: 330 HICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRGMVNELLVSF 151
HIC+TLQH PV +DFLRDLRE+V TV I+GGLAPIYGAAGK+PDRGM+ ELLV++
Sbjct: 49 HICVTLQHAPVFEDFLRDLRESVRTV------ISGGLAPIYGAAGKIPDRGMLEELLVNY 102
Query: 150 MDS 142
MDS
Sbjct: 103 MDS 105
[14][TOP]
>UniRef100_UPI00006A2233 Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL)
(Sphingosine-1-phosphate aldolase). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A2233
Length = 502
Score = 133 bits (334), Expect = 1e-29
Identities = 64/149 (42%), Positives = 101/149 (67%), Gaps = 4/149 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T KI++A++ +E +R+I E+F+ GKP+++++A GS DIF +++ +++KGW+L
Sbjct: 351 GYIEATKKIIKAARFIETELRKIKEIFIFGKPEVSVIALGSNKFDIFRLSNSLTAKGWNL 410
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+SIHIC+TL H V F++D++E+VE + +PG T GL IYG A +PD
Sbjct: 411 NTLQFPSSIHICLTLLHTKSGVAQQFVKDVKESVEVIMQDPGAKTTGLGAIYGMAQTIPD 470
Query: 183 RGMVNELLVSFMDSQY*VS*R--LKHLVG 103
R MV E+ +F+D Y R KH+ G
Sbjct: 471 RSMVTEISQAFLDCLYSTENRCSAKHING 499
[15][TOP]
>UniRef100_Q08VE4 Sphingosine-1-phosphate lyase 1 n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08VE4_STIAU
Length = 506
Score = 128 bits (322), Expect = 3e-28
Identities = 64/136 (47%), Positives = 95/136 (69%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ + I+E +K L+EG+ I EL V+G P + ++AFGSK LDI++V + M ++GW L
Sbjct: 371 GYLEASRHILETAKALKEGIAAIPELHVLGDP-LFVIAFGSKTLDIYKVMERMGARGWDL 429
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N L +P ++H+C+TL+H V + FL DLR AV V+ANPG G +AP+YG AG +P
Sbjct: 430 NGLHKPPAVHLCVTLRHTQPGVAERFLEDLRAAVAHVQANPGE-KGTMAPVYGMAGTVPF 488
Query: 183 RGMVNELLVSFMDSQY 136
RG++++LL +MD Y
Sbjct: 489 RGVLSDLLKKYMDLLY 504
[16][TOP]
>UniRef100_Q1D8D2 Putative sphingosine-1-phosphate lyase n=1 Tax=Myxococcus xanthus
DK 1622 RepID=Q1D8D2_MYXXD
Length = 509
Score = 127 bits (319), Expect = 7e-28
Identities = 61/136 (44%), Positives = 97/136 (71%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL T I+E + +++G+R+I EL V+G P + ++AFGS+++DIF+V + MS GW+L
Sbjct: 374 GYLDATRSILETAAAIKKGIRDIPELHVLGDP-LFVIAFGSESVDIFQVMERMSEHGWNL 432
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N L +P+++H+C+TL+H V + FL DLR+AV+ VK++P G +AP+YG A +P
Sbjct: 433 NGLHKPSAVHLCVTLRHTQPGVAEQFLVDLRDAVDYVKSHPS-AKGTMAPVYGMAASVPF 491
Query: 183 RGMVNELLVSFMDSQY 136
RG+V++LL +MD Y
Sbjct: 492 RGLVSDLLKKYMDLLY 507
[17][TOP]
>UniRef100_A7RKY4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RKY4_NEMVE
Length = 584
Score = 125 bits (313), Expect = 3e-27
Identities = 57/137 (41%), Positives = 91/137 (66%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T K+++ +R+E+G+R++ L+V G+P +++VAFGS DI+ + ++ +GW
Sbjct: 435 SGYVECTKKVLQTRERIEKGLRDVPGLYVFGEPIVSVVAFGSDKFDIYALGTALTGRGWC 494
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN+LQ P +IH+C+TL + V D FL+D+RE + A+P T GL IYG A +P
Sbjct: 495 LNSLQYPPAIHLCVTLLNTQPGVADRFLKDVRECAAKLLADPNAKTAGLGAIYGMAANIP 554
Query: 186 DRGMVNELLVSFMDSQY 136
DR +VNEL F+D Y
Sbjct: 555 DRSIVNELACGFLDCMY 571
[18][TOP]
>UniRef100_A4QNU7 Sphingosine-1-phosphate lyase 1 n=1 Tax=Danio rerio
RepID=A4QNU7_DANRE
Length = 572
Score = 124 bits (311), Expect = 6e-27
Identities = 56/136 (41%), Positives = 91/136 (66%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T K++E +++++ G+R+I +FV G P++++VA GS DIF +++ ++SKGW+L
Sbjct: 411 GYVEATRKVVETTRKIKTGIRKIDGVFVFGDPEVSVVALGSDDFDIFRLSNALTSKGWNL 470
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+SIHIC+T+ H V + F+ D+++ V + NP T G+ IYG A +PD
Sbjct: 471 NTLQFPSSIHICVTMLHTQSGVAEQFISDVKKEVAIIMKNPKEKTTGMGAIYGMAQSIPD 530
Query: 183 RGMVNELLVSFMDSQY 136
R MV E+ F+D Y
Sbjct: 531 RSMVTEVSQGFLDCLY 546
[19][TOP]
>UniRef100_B3S4N5 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
RepID=B3S4N5_TRIAD
Length = 426
Score = 124 bits (310), Expect = 8e-27
Identities = 57/137 (41%), Positives = 93/137 (67%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY+++T KI++A++R+++ ++E+ L+V+G P ++++A GSK DI+++N +MS KGW+
Sbjct: 288 SGYVKSTKKIIKAAQRIKDRIKEVDGLYVLGDPKLSVIAIGSKDFDIYQLNQLMSDKGWN 347
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LNALQ P SIHIC T+ H VV FLRD++E + P G A +YG A +P
Sbjct: 348 LNALQFPPSIHICCTMTHTQPGVVTKFLRDIKEVAAQLIQEPRKTPIGSAAMYGMAQTIP 407
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ +L +F+D Y
Sbjct: 408 DRSIITDLTNAFLDGIY 424
[20][TOP]
>UniRef100_UPI000155C7D7 PREDICTED: similar to sphingosine-1-phosphate lyase, partial n=1
Tax=Ornithorhynchus anatinus RepID=UPI000155C7D7
Length = 560
Score = 120 bits (301), Expect = 8e-26
Identities = 57/137 (41%), Positives = 91/137 (66%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T KI++ ++ L+ + I +F+ G P ++++A GS+ DIF +++++++KGW+
Sbjct: 406 SGYVEATKKIIKTARYLKSELETIKGIFIFGDPQVSVIALGSRDFDIFRLSNVLTAKGWN 465
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P+SIHIC+T H V FL+D+RE+V + NP T G+ IYG A +P
Sbjct: 466 LNQLQFPSSIHICLTQLHTKPGVATQFLKDVRESVTQIMKNPKAKTTGMGAIYGMAQGVP 525
Query: 186 DRGMVNELLVSFMDSQY 136
DR MV EL +F+DS Y
Sbjct: 526 DRKMVAELSQAFLDSLY 542
[21][TOP]
>UniRef100_Q54RV9 Sphingosine-1-phosphate lyase n=1 Tax=Dictyostelium discoideum
RepID=SGPL_DICDI
Length = 528
Score = 120 bits (300), Expect = 1e-25
Identities = 58/132 (43%), Positives = 89/132 (67%), Gaps = 1/132 (0%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
G+L+ +ME +K++ +G++ I+ + +IG P +VAF +IF VND MS KGWHL
Sbjct: 386 GFLEKAKGVMETTKKIIKGLQSINGVKIIGDPKAMVVAFTCD--NIFYVNDYMSKKGWHL 443
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPI-TGGLAPIYGAAGKMPDR 181
NALQRPNS+H+C+T + + + F+ DL+++++ VK N G + G APIYG+A +PDR
Sbjct: 444 NALQRPNSLHVCVTAKMIGMESLFIEDLKDSIKLVKDNSGSLPKDGTAPIYGSAHSVPDR 503
Query: 180 GMVNELLVSFMD 145
MV +L F+D
Sbjct: 504 EMVGTILSDFID 515
[22][TOP]
>UniRef100_UPI00016E6E7B UPI00016E6E7B related cluster n=1 Tax=Takifugu rubripes
RepID=UPI00016E6E7B
Length = 568
Score = 119 bits (297), Expect = 2e-25
Identities = 56/136 (41%), Positives = 87/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ T KI+ +++++ +R+I + V+G P++++VA GS DIF +++ ++SKGW+L
Sbjct: 416 GYIDATKKIISTARKIKTEIRKIKGVIVLGDPEISVVALGSDDFDIFRLSNALTSKGWNL 475
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIHIC T+ H V D F+RD++E V + NP T G+ IYG A +PD
Sbjct: 476 NTLQFPASIHICCTVLHTQPGVADHFIRDVKEQVAIIMKNPKERTTGMGAIYGMAQAIPD 535
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 536 RSLVTEISQGFLDCLY 551
[23][TOP]
>UniRef100_A7NKD8 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus castenholzii
DSM 13941 RepID=A7NKD8_ROSCS
Length = 498
Score = 118 bits (296), Expect = 3e-25
Identities = 60/136 (44%), Positives = 89/136 (65%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I+E ++R+ G+ I EL V+G P + ++AF S LDI+ V D M+ +GW+L
Sbjct: 363 GYLEATRRILETARRIRCGIESIPELRVLGDP-LWVIAFASMRLDIYRVLDQMAQRGWNL 421
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N L P +IHIC+TL H V D F+ DLR+AV V+ P GG+AP+YG A +P
Sbjct: 422 NGLHHPPAIHICVTLLHTQPGVADRFIADLRDAVAAVRREP-RARGGMAPVYGMAASLPF 480
Query: 183 RGMVNELLVSFMDSQY 136
R +V++LL ++D+ Y
Sbjct: 481 RSVVSDLLRRYLDAVY 496
[24][TOP]
>UniRef100_UPI0000F2AF77 PREDICTED: similar to sphingosine-1-phosphate lyase n=1
Tax=Monodelphis domestica RepID=UPI0000F2AF77
Length = 565
Score = 118 bits (295), Expect = 4e-25
Identities = 58/136 (42%), Positives = 89/136 (65%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T I+ ++ L+ + +I +FV G P ++++A GS+ DIF ++++M++KGW+L
Sbjct: 413 GYVEATKSIIRTARFLKSELEKIKGIFVFGNPQLSVIALGSRDFDIFRLSNLMTAKGWNL 472
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+SIHICIT+ H V FL+D+RE+V + NP T GL IYG + + D
Sbjct: 473 NILQFPSSIHICITMLHTRPKVSMQFLKDVRESVTQIMKNPKARTTGLGAIYGMSQTVSD 532
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL +F+DS Y
Sbjct: 533 RKMVAELTEAFLDSLY 548
[25][TOP]
>UniRef100_B3MD62 GF13423 n=1 Tax=Drosophila ananassae RepID=B3MD62_DROAN
Length = 545
Score = 117 bits (294), Expect = 5e-25
Identities = 54/136 (39%), Positives = 84/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I+ +FV GKP +++A GSK DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARHIERGVRDINGIFVFGKPATSVIALGSKKFDIFRLSDALCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
NALQ P+ IHIC+T H V D F+ D++ + +PG G +YG A +PD
Sbjct: 464 NALQFPSGIHICVTDMHTQPGVADKFIADVKSCTAEIMKDPGQPVQGKFALYGMAQSIPD 523
Query: 183 RGMVNELLVSFMDSQY 136
R ++ E+ F+ S Y
Sbjct: 524 RSVIGEVTRLFLHSMY 539
[26][TOP]
>UniRef100_UPI000180C1A9 PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Ciona
intestinalis RepID=UPI000180C1A9
Length = 562
Score = 117 bits (293), Expect = 7e-25
Identities = 55/136 (40%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ T KI+ ++ +E+G+R+I ++V+GKP+M++VA GS D+F ++ + +GW+L
Sbjct: 412 GYVNRTKKIITTARYIEQGLRKIEYIYVLGKPEMSVVALGSLDFDVFRLSTELVKRGWNL 471
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIHIC T+ H V D L+D+RE+V+ + ++P G IYG A +PD
Sbjct: 472 NNLQFPASIHICCTMPHTHPGVADRLLQDIRESVDIIMSDPKAKATGAGAIYGMAQSIPD 531
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D+ Y
Sbjct: 532 RSIVTEISHGFIDALY 547
[27][TOP]
>UniRef100_Q5ZMK8 Putative uncharacterized protein n=2 Tax=Gallus gallus
RepID=Q5ZMK8_CHICK
Length = 561
Score = 117 bits (293), Expect = 7e-25
Identities = 50/137 (36%), Positives = 94/137 (68%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T +I++ ++ LE +R+I +F+ GKP++++++ GS DI+ +++++++KGW+
Sbjct: 407 SGYVEATKRIIKTARFLESELRKIDSIFIFGKPEVSVLSIGSDTFDIYRLSNLLAAKGWN 466
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIH+CIT H V + FL+D+++++E + N T G+ IYG A +P
Sbjct: 467 LNILQFPPSIHLCITQLHTKSGVAEQFLKDVKDSIEDIMNNLNAKTTGMGAIYGMAQSIP 526
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V E+ ++++D Y
Sbjct: 527 DRSLVAEISLAYLDGLY 543
[28][TOP]
>UniRef100_B4N5T0 GK17932 n=1 Tax=Drosophila willistoni RepID=B4N5T0_DROWI
Length = 545
Score = 117 bits (293), Expect = 7e-25
Identities = 57/136 (41%), Positives = 83/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +FV GKP ++VA GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRQIDGVFVFGKPVTSVVAIGSTVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
NALQ P+ IHIC+T H V D F+ DLR V + +PG G +YG A +PD
Sbjct: 464 NALQFPSGIHICVTDMHTKPGVADKFIADLRSCVAEIMKDPGVPVEGKMALYGMAQSIPD 523
Query: 183 RGMVNELLVSFMDSQY 136
R ++ E+ F+ S Y
Sbjct: 524 RSVIGEVTRLFLHSMY 539
[29][TOP]
>UniRef100_B4KQG4 GI21004 n=1 Tax=Drosophila mojavensis RepID=B4KQG4_DROMO
Length = 544
Score = 117 bits (293), Expect = 7e-25
Identities = 58/137 (42%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +FV GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRQIDGIFVFGKPATSVIAIGSNVFDIFRLSDALCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IHIC+T H V D FL DLR + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHICVTDMHTRPGVADKFLADLRTCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[30][TOP]
>UniRef100_C3Y062 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3Y062_BRAFL
Length = 566
Score = 117 bits (292), Expect = 9e-25
Identities = 54/136 (39%), Positives = 93/136 (68%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+++T KI++A++ + + +R+I +FV G+P++++VAFGS+ DI+ V++ +++KGW+L
Sbjct: 415 GYVESTKKIVKAARYIAKELRKIDGIFVFGEPEVSVVAFGSEVFDIYRVSNTLTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+SIH+C TL H V D F+ D++ AV A+P T G IYG A +PD
Sbjct: 475 NSLQFPSSIHLCCTLCHTLPGVTDRFINDVKNAVADALADPQAKTTGQGAIYGMAQSVPD 534
Query: 183 RGMVNELLVSFMDSQY 136
R ++ ++ ++D Y
Sbjct: 535 RKIIADIAWGYLDCVY 550
[31][TOP]
>UniRef100_UPI000194C945 PREDICTED: sphingosine-1-phosphate lyase 1 n=1 Tax=Taeniopygia
guttata RepID=UPI000194C945
Length = 700
Score = 116 bits (291), Expect = 1e-24
Identities = 50/137 (36%), Positives = 93/137 (67%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T +I++ ++ LE +R+I +F+ GKP++++++ GS DI+ +++ +++KGW+
Sbjct: 546 SGYVEATKRIIKTARFLESELRKIDSIFIFGKPEVSVLSIGSDTFDIYRLSNFLAAKGWN 605
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIH+CIT H V + FL+D+R++++ + + G T G+ IYG A +P
Sbjct: 606 LNVLQFPPSIHLCITQLHTKPGVAEQFLKDVRDSIQDIMKDLGAKTTGMGAIYGMAQSVP 665
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V E+ +++D Y
Sbjct: 666 DRSLVAEISQAYLDGLY 682
[32][TOP]
>UniRef100_Q290S2 GA21426 n=1 Tax=Drosophila pseudoobscura pseudoobscura
RepID=Q290S2_DROPS
Length = 545
Score = 116 bits (291), Expect = 1e-24
Identities = 57/137 (41%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I LFV GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRDIDGLFVFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IHIC+T H V D F+ D+R + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHICVTDMHTQAGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[33][TOP]
>UniRef100_B4GBB4 GL10551 n=1 Tax=Drosophila persimilis RepID=B4GBB4_DROPE
Length = 527
Score = 116 bits (291), Expect = 1e-24
Identities = 57/137 (41%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I LFV GKP +++A GS DIF ++D + GW+L
Sbjct: 386 GYLEATKRIVDTARYIERGVRDIDGLFVFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 445
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IHIC+T H V D F+ D+R + +PG P+ G +A +YG A +P
Sbjct: 446 NALQFPSGIHICVTDMHTQAGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIP 504
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 505 DRSVIGEVTRLFLHSMY 521
[34][TOP]
>UniRef100_B4LKG7 GJ20717 n=1 Tax=Drosophila virilis RepID=B4LKG7_DROVI
Length = 544
Score = 116 bits (290), Expect = 2e-24
Identities = 58/137 (42%), Positives = 85/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +FV GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRQIDGIFVFGKPATSVIAMGSNVFDIFRLSDALCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
N LQ P+ IHICIT H V D FL DLR + +PG P+ G +A +YG A +P
Sbjct: 464 NPLQFPSGIHICITDMHTQAGVADKFLADLRTCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[35][TOP]
>UniRef100_UPI00017B2759 UPI00017B2759 related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B2759
Length = 567
Score = 115 bits (288), Expect = 3e-24
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T K++ +++++ +R+I + V+G P++++VA GS DIF +++ +++KGW+L
Sbjct: 415 GYVEATKKVISTARKIKTEIRKIKGVMVLGDPEVSVVALGSDHFDIFRLSNALTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+SIHIC T+ H V D F+ D++E V + NP T G+ IYG A +PD
Sbjct: 475 NTLQFPSSIHICCTVLHTQPGVADRFIGDVKEEVAIIMKNPEERTTGMGAIYGMAQAIPD 534
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 535 RSLVTEISRGFLDCLY 550
[36][TOP]
>UniRef100_Q4S3S0 Chromosome 17 SCAF14747, whole genome shotgun sequence. (Fragment)
n=1 Tax=Tetraodon nigroviridis RepID=Q4S3S0_TETNG
Length = 595
Score = 115 bits (288), Expect = 3e-24
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T K++ +++++ +R+I + V+G P++++VA GS DIF +++ +++KGW+L
Sbjct: 445 GYVEATKKVISTARKIKTEIRKIKGVMVLGDPEVSVVALGSDHFDIFRLSNALTAKGWNL 504
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+SIHIC T+ H V D F+ D++E V + NP T G+ IYG A +PD
Sbjct: 505 NTLQFPSSIHICCTVLHTQPGVADRFIGDVKEEVAIIMKNPEERTTGMGAIYGMAQAIPD 564
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 565 RSLVTEISRGFLDCLY 580
[37][TOP]
>UniRef100_B3NP20 GG22218 n=1 Tax=Drosophila erecta RepID=B3NP20_DROER
Length = 545
Score = 115 bits (288), Expect = 3e-24
Identities = 54/137 (39%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I+ +F+ GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRDINGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IH+C+T H V D F+ D+R + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[38][TOP]
>UniRef100_UPI0000E224B9 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 2 n=1 Tax=Pan
troglodytes RepID=UPI0000E224B9
Length = 488
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 335 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 394
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 395 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 454
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 455 RNMVAELSSVFLDSLY 470
[39][TOP]
>UniRef100_UPI0000E224B8 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 6 n=1 Tax=Pan
troglodytes RepID=UPI0000E224B8
Length = 568
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 534
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 535 RNMVAELSSVFLDSLY 550
[40][TOP]
>UniRef100_UPI0000E224B7 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 1 n=1 Tax=Pan
troglodytes RepID=UPI0000E224B7
Length = 569
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 416 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 475
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 476 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 535
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 536 RNMVAELSSVFLDSLY 551
[41][TOP]
>UniRef100_UPI0000D9C37C PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1
Tax=Macaca mulatta RepID=UPI0000D9C37C
Length = 633
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 480 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 539
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 540 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 599
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 600 RNMVAELSSVFLDSLY 615
[42][TOP]
>UniRef100_A5UWH0 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus sp. RS-1
RepID=A5UWH0_ROSS1
Length = 498
Score = 114 bits (286), Expect = 5e-24
Identities = 55/136 (40%), Positives = 87/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I+E + R+ G+ I EL ++G P + ++AF + LDI+ + D M+ +GW+L
Sbjct: 363 GYLEATRRILETAHRIRTGIEAIPELRILGDP-LWVIAFTATRLDIYRILDRMAQRGWNL 421
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N L P ++HIC+TL H V D F+ DLR++V V+ P GG+AP+YG A +P
Sbjct: 422 NGLHHPPAVHICVTLPHTAPGVADRFIADLRDSVAAVRREP-RARGGMAPVYGMAASLPF 480
Query: 183 RGMVNELLVSFMDSQY 136
RG++ +LL ++D Y
Sbjct: 481 RGVIGDLLRRYLDVVY 496
[43][TOP]
>UniRef100_B4P8H4 GE14215 n=1 Tax=Drosophila yakuba RepID=B4P8H4_DROYA
Length = 545
Score = 114 bits (286), Expect = 5e-24
Identities = 54/137 (39%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E G+R+I +F+ GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGLRDIDGVFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IH+C+T H V D F+ D+R V + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHLCVTDMHTQPGVADKFIADVRSCVAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[44][TOP]
>UniRef100_B4QIK3 GD25496 n=2 Tax=melanogaster subgroup RepID=B4QIK3_DROSI
Length = 545
Score = 114 bits (286), Expect = 5e-24
Identities = 54/137 (39%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +F+ GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IH+C+T H V D F+ D+R + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[45][TOP]
>UniRef100_Q9V7Y2 Sphingosine-1-phosphate lyase n=1 Tax=Drosophila melanogaster
RepID=SGPL_DROME
Length = 545
Score = 114 bits (286), Expect = 5e-24
Identities = 54/137 (39%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +F+ GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
NALQ P+ IH+C+T H V D F+ D+R + +PG P+ G +A +YG A +P
Sbjct: 464 NALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQSIP 522
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ E+ F+ S Y
Sbjct: 523 DRSVIGEVTRLFLHSMY 539
[46][TOP]
>UniRef100_Q5R4G0 Sphingosine-1-phosphate lyase 1 n=1 Tax=Pongo abelii
RepID=SGPL1_PONAB
Length = 568
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 534
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 535 RNMVAELSSVFLDSLY 550
[47][TOP]
>UniRef100_O95470 Sphingosine-1-phosphate lyase 1 n=1 Tax=Homo sapiens
RepID=SGPL1_HUMAN
Length = 568
Score = 114 bits (286), Expect = 5e-24
Identities = 57/136 (41%), Positives = 86/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ ++++M++KGW+L
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTVD 534
Query: 183 RGMVNELLVSFMDSQY 136
R MV EL F+DS Y
Sbjct: 535 RNMVAELSSVFLDSLY 550
[48][TOP]
>UniRef100_A6GEB7 Putative sphingosine-1-phosphate lyase n=1 Tax=Plesiocystis
pacifica SIR-1 RepID=A6GEB7_9DELT
Length = 509
Score = 114 bits (285), Expect = 6e-24
Identities = 62/138 (44%), Positives = 89/138 (64%), Gaps = 4/138 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF--GSKALDIFEVNDIMSSKGW 364
GYL T +I+E +++ G+ I L V+G P + +V+F G + L+I+EV D M K W
Sbjct: 372 GYLDATKRIVETGQKIRRGIDAILGLKVLGDP-LWVVSFASGEEGLNIYEVLDAMGKKHW 430
Query: 363 HLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM 190
+LN L RP +H+ +TL+H V + FL DLREAVE +ANPG G+APIYG AG +
Sbjct: 431 NLNGLHRPPCVHLAVTLRHTKEGVAERFLDDLREAVEHTRANPGE-GSGMAPIYGLAGTI 489
Query: 189 PDRGMVNELLVSFMDSQY 136
P RG V++LL ++D+ Y
Sbjct: 490 PARGAVSDLLEMYLDAVY 507
[49][TOP]
>UniRef100_UPI00018614E7 hypothetical protein BRAFLDRAFT_277715 n=1 Tax=Branchiostoma
floridae RepID=UPI00018614E7
Length = 566
Score = 113 bits (283), Expect = 1e-23
Identities = 52/136 (38%), Positives = 92/136 (67%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+++T KI++A++ + + +++I +FV G+P++++VAFGS+ DI+ V++ +++KGW+L
Sbjct: 415 GYVESTKKIVKAARYIAKELKKIDGIFVFGEPEVSVVAFGSEVFDIYRVSNTLTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+ Q P+SIH+C TL H V D F+ D++ AV A+P T G IYG A +PD
Sbjct: 475 NSQQFPSSIHLCCTLCHTLPGVTDRFINDVKNAVADALADPQAKTTGQGAIYGMAQSVPD 534
Query: 183 RGMVNELLVSFMDSQY 136
R ++ ++ ++D Y
Sbjct: 535 RKIIADIAWGYLDCVY 550
[50][TOP]
>UniRef100_C1FD78 Sphingosine-1-phosphate lyase n=1 Tax=Micromonas sp. RCC299
RepID=C1FD78_9CHLO
Length = 561
Score = 113 bits (283), Expect = 1e-23
Identities = 63/134 (47%), Positives = 83/134 (61%), Gaps = 3/134 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSSKGW 364
GY T KI AS RL G+ +I L V+G +VA+GS LDI+ VNDIM +KGW
Sbjct: 422 GYKVMTEKICSASARLRAGISQIRGLQVLGSDVTMVVAWGSTDPLLDIYVVNDIMITKGW 481
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAV-ETVKANPGPITGGLAPIYGAAGKMP 187
HL+ L P ++H+CIT ++ V + L DLREAV E +N I+GG APIYG AG +P
Sbjct: 482 HLSVLHTPAALHMCITPANLERVPELLSDLREAVDEAQNSNDEGISGGKAPIYGLAGALP 541
Query: 186 DRGMVNELLVSFMD 145
DR +V ++L D
Sbjct: 542 DRDLVGDILKDVQD 555
[51][TOP]
>UniRef100_B2W874 Sphingosine-1-phosphate lyase 1 n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2W874_PYRTR
Length = 567
Score = 113 bits (282), Expect = 1e-23
Identities = 62/149 (41%), Positives = 87/149 (58%), Gaps = 15/149 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELF----VIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
GYL KI+ K++E +RE EL +IG+P +++VAF S LDI+++ D MSSK
Sbjct: 417 GYLDACHKIVGGMKQIETAIREKPELSSDLKIIGRPLVSVVAFLSNTLDIYDIADGMSSK 476
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-----------KANPGPITGG 223
GWHLNALQ P +IH+ +TL V VVD + DL E E V K G + G
Sbjct: 477 GWHLNALQSPPAIHVAVTLPIVAVVDKLIEDLVEVTEDVREKERKRIAEGKGAKGAVKGD 536
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V +L F+D+ Y
Sbjct: 537 AAALYGVAGSLPNKSVVEDLAKGFLDTLY 565
[52][TOP]
>UniRef100_UPI0001B79B0A Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (SPL)
(Sphingosine-1-phosphate aldolase). n=1 Tax=Rattus
norvegicus RepID=UPI0001B79B0A
Length = 568
Score = 112 bits (280), Expect = 2e-23
Identities = 55/136 (40%), Positives = 85/136 (62%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +F++G P ++++A GS DI+ ++++MS+KGW+
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNF 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R MV E+ F+DS Y
Sbjct: 535 RKMVAEISSVFLDSLY 550
[53][TOP]
>UniRef100_B4J547 GH20882 n=1 Tax=Drosophila grimshawi RepID=B4J547_DROGR
Length = 544
Score = 112 bits (280), Expect = 2e-23
Identities = 53/136 (38%), Positives = 81/136 (59%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ T +I++ ++ +E GVR+I +F+ GKP +++A GS DIF ++D + GW+L
Sbjct: 404 GYLEATKRIVDTARYIERGVRQIDGIFIFGKPATSVIAMGSNVFDIFRLSDALCKLGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+ IHICIT H V D F+ DLR + +PG G +YG A +PD
Sbjct: 464 NPLQFPSGIHICITDMHTKPGVADKFVADLRTCTAEIMKDPGQPVVGKFALYGMAQSIPD 523
Query: 183 RGMVNELLVSFMDSQY 136
R ++ E+ ++ S Y
Sbjct: 524 RSVIGEVTRLYIHSMY 539
[54][TOP]
>UniRef100_Q8CHN6 Sphingosine-1-phosphate lyase 1 n=1 Tax=Rattus norvegicus
RepID=SGPL1_RAT
Length = 568
Score = 112 bits (280), Expect = 2e-23
Identities = 55/136 (40%), Positives = 85/136 (62%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +F++G P ++++A GS DI+ ++++MS+KGW+
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNF 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R MV E+ F+DS Y
Sbjct: 535 RKMVAEISSVFLDSLY 550
[55][TOP]
>UniRef100_UPI00005872F7 PREDICTED: hypothetical protein n=1 Tax=Strongylocentrotus
purpuratus RepID=UPI00005872F7
Length = 422
Score = 111 bits (278), Expect = 4e-23
Identities = 48/136 (35%), Positives = 87/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++NT KI+ ++++ E V +I LFV G P++++V GSK +I+ ++ ++ +GW+L
Sbjct: 281 GYVENTRKIVSTTRKVAEEVGKIPGLFVYGNPEVSVVGVGSKVFNIYRLSGALTERGWNL 340
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+S H+C+TL+ V + F++D++E E + P G A +YG A +PD
Sbjct: 341 NSLQFPSSFHLCVTLRQTFPGVAEQFIQDVKECTEEIMKTPNEKASGSAALYGTAQAIPD 400
Query: 183 RGMVNELLVSFMDSQY 136
R +V ++ ++D+ Y
Sbjct: 401 RSLVTDMARGYLDAYY 416
[56][TOP]
>UniRef100_Q6FSD9 Strain CBS138 chromosome H complete sequence n=1 Tax=Candida
glabrata RepID=Q6FSD9_CANGA
Length = 565
Score = 111 bits (278), Expect = 4e-23
Identities = 51/138 (36%), Positives = 93/138 (67%), Gaps = 3/138 (2%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVR-EIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW 364
+GY + ++I+ +++L++ +R ++ +L V+G P +++V+F S L+I+E+ D ++ GW
Sbjct: 423 SGYKDSCTRIVSTARKLKDHIRNKLPQLEVLGDPKLSVVSFSSNKLNIYELADRLAKSGW 482
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANP--GPITGGLAPIYGAAGKM 190
HLNALQ+P ++H+ IT VP +D F+ L EAVE + A+P P T G + +YG AG +
Sbjct: 483 HLNALQKPAALHLAITTLSVPTIDTFIETLTEAVEQMSADPTSTPSTEGTSALYGVAGSV 542
Query: 189 PDRGMVNELLVSFMDSQY 136
G+ ++L+ +F+D+ Y
Sbjct: 543 KTTGVADKLITAFLDTLY 560
[57][TOP]
>UniRef100_UPI000155D8B9 PREDICTED: sphingosine-1-phosphate lyase 1 n=1 Tax=Equus caballus
RepID=UPI000155D8B9
Length = 568
Score = 111 bits (277), Expect = 5e-23
Identities = 55/137 (40%), Positives = 87/137 (63%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T +I++ ++ L+ + +I +FV G P ++++A GS+ DI+ + ++M++KGW+
Sbjct: 414 SGYVEATKQIIKTARFLKSELEKIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWN 473
Query: 360 LNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A
Sbjct: 474 LNQLQFPPSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTV 533
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V EL F+DS +
Sbjct: 534 DRNLVAELSSVFLDSLF 550
[58][TOP]
>UniRef100_UPI00017F051B PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Sus
scrofa RepID=UPI00017F051B
Length = 568
Score = 110 bits (276), Expect = 7e-23
Identities = 56/136 (41%), Positives = 85/136 (62%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DIF + ++M++KGW+L
Sbjct: 415 GYVEATKQIIKTTRFLKAELENIKGIFVFGNPQLSVIALGSRDFDIFRLFNLMTAKGWNL 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NQLQFPPSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R +V EL F+DS +
Sbjct: 535 RNLVAELSSFFLDSLF 550
[59][TOP]
>UniRef100_UPI0000EB3D58 Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL)
(Sphingosine-1-phosphate aldolase). n=1 Tax=Canis lupus
familiaris RepID=UPI0000EB3D58
Length = 568
Score = 110 bits (275), Expect = 9e-23
Identities = 55/137 (40%), Positives = 86/137 (62%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ + ++M++KGW+
Sbjct: 414 SGYVEATKQIIKTTRFLKSELETIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWN 473
Query: 360 LNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A
Sbjct: 474 LNQLQFPPSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTV 533
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V EL F+DS +
Sbjct: 534 DRNLVAELSSVFLDSLF 550
[60][TOP]
>UniRef100_UPI00005A07E0 PREDICTED: similar to sphingosine-1-phosphate lyase 1 n=1 Tax=Canis
lupus familiaris RepID=UPI00005A07E0
Length = 568
Score = 110 bits (275), Expect = 9e-23
Identities = 55/137 (40%), Positives = 86/137 (62%), Gaps = 2/137 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ + ++M++KGW+
Sbjct: 414 SGYVEATKQIIKTTRFLKSELETIKGIFVFGNPQLSVIALGSRDFDIYRLFNLMTAKGWN 473
Query: 360 LNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A
Sbjct: 474 LNQLQFPPSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQTTV 533
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V EL F+DS +
Sbjct: 534 DRNLVAELSSVFLDSLF 550
[61][TOP]
>UniRef100_A5D788 SGPL1 protein n=1 Tax=Bos taurus RepID=A5D788_BOVIN
Length = 568
Score = 110 bits (275), Expect = 9e-23
Identities = 55/144 (38%), Positives = 89/144 (61%), Gaps = 2/144 (1%)
Frame = -1
Query: 561 SVCFCCSTGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDI 382
S+ + +GY++ T +I++ ++ L+ + I +FV G P ++++A GS+ DI+ + ++
Sbjct: 407 SLMYFGESGYVEATKQIIKTTRFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLFNL 466
Query: 381 MSSKGWHLNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIY 208
M++KGW+LN LQ P S+H CITL H V FL+D+RE+V + NP T G+ IY
Sbjct: 467 MNAKGWNLNQLQFPPSLHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIY 526
Query: 207 GAAGKMPDRGMVNELLVSFMDSQY 136
G A DR +V EL F+DS +
Sbjct: 527 GMAQATIDRNLVAELSSVFLDSLF 550
[62][TOP]
>UniRef100_Q0UKS0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UKS0_PHANO
Length = 580
Score = 110 bits (275), Expect = 9e-23
Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 15/149 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELF----VIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
GY+ KI+ K++E +RE EL VIGKP +++V+F S +DI+++ D MS K
Sbjct: 430 GYIDACHKIVGGMKKIESAIRERPELASDLKVIGKPLVSVVSFLSDTIDIYDIADGMSGK 489
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-----------KANPGPITGG 223
GWHLNALQ P +IHI +TL V VVD + DL E E V K G + G
Sbjct: 490 GWHLNALQNPPAIHIAVTLPIVAVVDKLIEDLVEVTEDVKDKERRRIAEGKGAKGAVKGD 549
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V +L F+D+ Y
Sbjct: 550 AAALYGVAGSLPNKSVVVDLAKGFLDTLY 578
[63][TOP]
>UniRef100_Q8R0X7 Sphingosine-1-phosphate lyase 1 n=2 Tax=Mus musculus
RepID=SGPL1_MOUSE
Length = 568
Score = 108 bits (270), Expect = 3e-22
Identities = 53/136 (38%), Positives = 83/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +F+ G P ++++A GS DI+ ++++MS+KGW+
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNF 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 535 RKLVAEISSVFLDCLY 550
[64][TOP]
>UniRef100_Q4FK38 Sgpl1 protein n=1 Tax=Mus musculus RepID=Q4FK38_MOUSE
Length = 568
Score = 108 bits (270), Expect = 3e-22
Identities = 53/136 (38%), Positives = 83/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +F+ G P ++++A GS DI+ ++++MS+KGW+
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNF 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 535 RKLVAEISSVFLDCLY 550
[65][TOP]
>UniRef100_Q3UDJ2 Putative uncharacterized protein n=1 Tax=Mus musculus
RepID=Q3UDJ2_MOUSE
Length = 568
Score = 108 bits (270), Expect = 3e-22
Identities = 53/136 (38%), Positives = 83/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ L+ + I +F+ G P ++++A GS DI+ ++++MS+KGW+
Sbjct: 415 GYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNF 474
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P SIH CITL H V FL+D+RE+V + NP T G+ IYG A D
Sbjct: 475 NYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATID 534
Query: 183 RGMVNELLVSFMDSQY 136
R +V E+ F+D Y
Sbjct: 535 RKLVAEISSVFLDCLY 550
[66][TOP]
>UniRef100_Q17G38 Sphingosine phosphate lyase n=1 Tax=Aedes aegypti
RepID=Q17G38_AEDAE
Length = 538
Score = 108 bits (269), Expect = 4e-22
Identities = 51/136 (37%), Positives = 82/136 (60%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ +E +R++ ++V G P ++VA GSK DIF ++ ++S GW+L
Sbjct: 397 GYVEATKRIIDTARYIEAQLRKVDSIYVFGTPATSVVAIGSKDFDIFRLSAELNSLGWNL 456
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+ IHIC+T H + D F+ D+R V V NP G IYG A +PD
Sbjct: 457 NSLQFPSGIHICVTYMHTQDGIADKFVNDVRTKVALVMKNPEKPVEGKMAIYGVAQAVPD 516
Query: 183 RGMVNELLVSFMDSQY 136
R ++ + F+DS Y
Sbjct: 517 REVIGDFTKCFIDSMY 532
[67][TOP]
>UniRef100_Q7PY31 AGAP001724-PA n=1 Tax=Anopheles gambiae RepID=Q7PY31_ANOGA
Length = 519
Score = 107 bits (267), Expect = 7e-22
Identities = 49/136 (36%), Positives = 81/136 (59%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ +E+ +R I +F+ G P +++ GS+ DIF + +S+ GW+L
Sbjct: 374 GYVEATKRIIDTTRYIEQELRAIKNIFIFGTPATSVIGIGSRDFDIFLLGGELSNLGWNL 433
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+ IHIC+T H V D F++D+R V + NP G IYG A +PD
Sbjct: 434 NSLQFPSGIHICVTYMHTEAGVADKFIQDVRSKVALIMKNPTKPVEGKMAIYGVAQSVPD 493
Query: 183 RGMVNELLVSFMDSQY 136
R ++ + F+DS Y
Sbjct: 494 RELIGDFTKCFIDSMY 509
[68][TOP]
>UniRef100_B0XFI0 Sphingosine-1-phosphate lyase n=1 Tax=Culex quinquefasciatus
RepID=B0XFI0_CULQU
Length = 539
Score = 107 bits (266), Expect = 1e-21
Identities = 51/136 (37%), Positives = 81/136 (59%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T +I++ ++ +E +R+I +++ G P ++VA GSK DIF ++ ++ GW+L
Sbjct: 397 GYVERTRRIIDTARYIETELRKIDNIYIFGTPATSVVAIGSKDFDIFRLSGELNGLGWNL 456
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+ IHIC+T H + D F+ D+R V NP G IYG A ++PD
Sbjct: 457 NSLQFPSGIHICVTHMHTQNGIADKFVADVRSKVALCMQNPEKPVEGKMAIYGVAQEVPD 516
Query: 183 RGMVNELLVSFMDSQY 136
R +V E F+DS Y
Sbjct: 517 REVVGEFTKCFIDSMY 532
[69][TOP]
>UniRef100_C1US47 PLP-dependent enzyme, glutamate decarboxylase n=1 Tax=Haliangium
ochraceum DSM 14365 RepID=C1US47_9DELT
Length = 513
Score = 106 bits (265), Expect = 1e-21
Identities = 54/136 (39%), Positives = 80/136 (58%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSSKGW 364
GYL + +IMEA+ R G+ I L + G P M++V FG++ LDIF V D + +GW
Sbjct: 327 GYLDSARQIMEATDRFVAGIHTIDGLQIFGAPHMSLVCFGARDPELDIFAVADALERRGW 386
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
H++ Q PNSIH+ + QH+ V++ +L D+ EAV+ V+A+P T G A +YG KMP
Sbjct: 387 HIDRQQSPNSIHVTLMPQHLEVLERYLSDIAEAVDEVRADPSLRTQGQAAMYGMMAKMPF 446
Query: 183 RGMVNELLVSFMDSQY 136
+ +V M Y
Sbjct: 447 ARITRRGVVELMKQMY 462
[70][TOP]
>UniRef100_Q4JSA1 Sply, Sphingosine-phosphate lyase n=1 Tax=Anopheles gambiae
RepID=Q4JSA1_ANOGA
Length = 519
Score = 106 bits (264), Expect = 2e-21
Identities = 49/136 (36%), Positives = 80/136 (58%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T I++ ++ +E+ +R I +F+ G P +++ GS+ DIF + +S+ GW+L
Sbjct: 374 GYVEATKHIIDTTRYIEQELRAIKNIFIFGTPATSVIGIGSRDFDIFLLGGELSNLGWNL 433
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N+LQ P+ IHIC+T H V D F++D+R V + NP G IYG A +PD
Sbjct: 434 NSLQFPSGIHICVTYMHTEAGVADKFIQDVRSKVALIMKNPTKPVEGKMAIYGVAQSVPD 493
Query: 183 RGMVNELLVSFMDSQY 136
R ++ + F+DS Y
Sbjct: 494 RELIGDFTKCFIDSMY 509
[71][TOP]
>UniRef100_Q67PY4 Putative sphingosine-1-phosphate lyase n=1 Tax=Symbiobacterium
thermophilum RepID=Q67PY4_SYMTH
Length = 507
Score = 105 bits (263), Expect = 2e-21
Identities = 57/136 (41%), Positives = 87/136 (63%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL T +I++A+ RL+ GVR I L ++G P + ++A S L+I++V + M+ +GW L
Sbjct: 373 GYLDATRRILQAADRLKAGVRAIPSLKILGDP-LWVIAVASDELNIYQVMEEMAGRGWRL 431
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N L RP + H+ +TL+H VVD FL DL++AV V+A+P T G+AP+YG A P
Sbjct: 432 NGLHRPPAFHVALTLRHTEPGVVDRFLADLQDAVAQVRAHPEKAT-GMAPVYGMAAAAPP 490
Query: 183 RGMVNELLVSFMDSQY 136
+V ++L F+D Y
Sbjct: 491 E-LVRQVLTGFIDLLY 505
[72][TOP]
>UniRef100_A7EYG6 Putative uncharacterized protein n=1 Tax=Sclerotinia sclerotiorum
1980 UF-70 RepID=A7EYG6_SCLS1
Length = 529
Score = 105 bits (261), Expect = 4e-21
Identities = 58/150 (38%), Positives = 90/150 (60%), Gaps = 15/150 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH----ELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
TGY+ ++I+ A+K++ E + E +L ++GKP +++VAF SK LDI+++ D MS+
Sbjct: 378 TGYINACAEIVGATKKIIEAINENPSLNGDLHILGKPLVSVVAFTSKTLDIYDIADAMSA 437
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDL---------REAVETV--KANPGPITG 226
KGWHLN+LQ P +IH+ +TL V V + + DL +E V V K G G
Sbjct: 438 KGWHLNSLQSPPAIHVAVTLPIVKVREKLIEDLIAVVEGEKEKERVRIVEGKGAKGKSLG 497
Query: 225 GLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V EL F+D+ Y
Sbjct: 498 DSAALYGVAGSLPNKSVVVELASGFLDTLY 527
[73][TOP]
>UniRef100_A6SSH1 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6SSH1_BOTFB
Length = 157
Score = 105 bits (261), Expect = 4e-21
Identities = 58/150 (38%), Positives = 90/150 (60%), Gaps = 15/150 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH----ELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
TGY+ + ++I+ A+K++ + + E +L V+GKP +++VAF SK LDI+++ D MS
Sbjct: 6 TGYINSCNEIVGATKKIIDSISENPSLNADLHVLGKPLVSVVAFTSKTLDIYDIADAMSG 65
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDL---------REAVETV--KANPGPITG 226
KGWHLN+LQ P +IH+ +TL V V + + DL +E V V K G G
Sbjct: 66 KGWHLNSLQNPPAIHVAVTLPIVKVWEKLIEDLIAVVEGEKEKERVRIVEGKGAKGKSLG 125
Query: 225 GLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V EL F+D+ Y
Sbjct: 126 DSAALYGVAGSLPNKSVVVELASGFLDTLY 155
[74][TOP]
>UniRef100_C1UZK8 PLP-dependent enzyme, glutamate decarboxylase n=1 Tax=Haliangium
ochraceum DSM 14365 RepID=C1UZK8_9DELT
Length = 514
Score = 104 bits (260), Expect = 5e-21
Identities = 54/140 (38%), Positives = 88/140 (62%), Gaps = 4/140 (2%)
Frame = -1
Query: 543 STGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSSK 370
+ GY ++I++A++R++ G+R + + ++G P + ++AF ++ +DI+ V MS +
Sbjct: 375 AAGYRDAAARILDAAERIKTGLRALPAIEILGDP-LWVIAFAARDERVDIYRVMARMSQR 433
Query: 369 GWHLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAG 196
GW LN L RP +H+C+TL+H V + F+ DL EA+ V+A PG G AP+YG A
Sbjct: 434 GWSLNGLHRPACVHLCVTLRHAEPGVAERFVADLGEAIAEVEAAPGEAEGA-APVYGMAA 492
Query: 195 KMPDRGMVNELLVSFMDSQY 136
+P RGMV E+L +MD Y
Sbjct: 493 TIPVRGMVGEMLRRYMDLLY 512
[75][TOP]
>UniRef100_UPI000051A46E PREDICTED: similar to Sphingosine-1-phosphate lyase CG8946-PA,
isoform A n=1 Tax=Apis mellifera RepID=UPI000051A46E
Length = 549
Score = 104 bits (259), Expect = 6e-21
Identities = 47/135 (34%), Positives = 82/135 (60%), Gaps = 2/135 (1%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLN 355
YL++T KI++ ++ +E+ +R++ +F+ G P +++A GS I+++++ +++KGW+LN
Sbjct: 401 YLESTKKIIKTTRYIEQRLRKLKGIFIFGTPATSVIALGSNDFHIYKLSEALNAKGWNLN 460
Query: 354 ALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDR 181
LQ P IH+C+T H V D FL D+ +E + NP G IYG + +PDR
Sbjct: 461 TLQFPCGIHLCVTYVHTQSGVADQFLSDVETELEEILKNPETPVEGKFAIYGMSQSIPDR 520
Query: 180 GMVNELLVSFMDSQY 136
+V + F+DS Y
Sbjct: 521 SIVGDFAKCFLDSMY 535
[76][TOP]
>UniRef100_Q6C4B5 YALI0E28237p n=1 Tax=Yarrowia lipolytica RepID=Q6C4B5_YARLI
Length = 448
Score = 102 bits (254), Expect = 2e-20
Identities = 50/136 (36%), Positives = 82/136 (60%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGV-REIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GYL++ +I+ A+++ + V EI +L +IG P +++AFGS +++I++++D MS KGWH
Sbjct: 311 GYLESCKEIVGAARKFRKAVDEEIPDLQIIGDPRASVIAFGSDSVNIYDLSDAMSKKGWH 370
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREA-VETVKANPGPITGGLAPIYGAAGKMPD 184
L+ LQ P + H+ T V VDD + DL+ +E KA + G A YG AG +
Sbjct: 371 LSTLQNPPAAHVAFTKPAVAAVDDLVSDLKSCIIEMKKAGNTKVEDGTAAFYGVAGSIKT 430
Query: 183 RGMVNELLVSFMDSQY 136
G+ + L+ F+D Y
Sbjct: 431 AGVADRLVCGFLDGLY 446
[77][TOP]
>UniRef100_UPI000186EA0D Sply, sphingosine-phosphate lyase, putative n=1 Tax=Pediculus
humanus corporis RepID=UPI000186EA0D
Length = 554
Score = 101 bits (251), Expect = 5e-20
Identities = 47/135 (34%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY++ T I+ +K +E ++EI E+FV G P ++VA GS I+ ++D +S GW+
Sbjct: 401 SGYVETTKAIISTTKYIENKLKEIDEIFVFGSPITSVVAIGSNTFHIYRLSDALSKCGWN 460
Query: 360 LNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P IH+C+T H V + F+ D++ V + NP G +YG + +P
Sbjct: 461 LNPLQYPPGIHLCVTNLHTRKGVAESFIEDVKREVAVIMKNPDEEVKGKMAMYGTSANLP 520
Query: 186 DRGMVNELLVSFMDS 142
DR +V + F+D+
Sbjct: 521 DRTVVGDFARIFLDA 535
[78][TOP]
>UniRef100_UPI0000D555CD PREDICTED: similar to sphingosine phosphate lyase isoform 1 n=1
Tax=Tribolium castaneum RepID=UPI0000D555CD
Length = 543
Score = 100 bits (250), Expect = 7e-20
Identities = 47/136 (34%), Positives = 77/136 (56%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+Q T I+ ++ +E+G+R + +F+ G+P +++A GS I+ + ++ GW+L
Sbjct: 402 GYVQATRDIIHTTRYIEKGLRRMKGIFIFGQPATSVIALGSNDFHIYRLGSALNKLGWNL 461
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P+ IHIC+T H V D FL D++ ++ + P G IYG A +PD
Sbjct: 462 NVLQFPSGIHICVTHMHTQQGVADKFLNDVQNSLAEILKEPDVPVEGKMAIYGVAQSVPD 521
Query: 183 RGMVNELLVSFMDSQY 136
R +V + F+DS Y
Sbjct: 522 RSIVTDFTRLFLDSMY 537
[79][TOP]
>UniRef100_C1MXR5 Sphingosine-1-phosphate lyase n=1 Tax=Micromonas pusilla CCMP1545
RepID=C1MXR5_9CHLO
Length = 561
Score = 100 bits (250), Expect = 7e-20
Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 3/134 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSSKGW 364
GY + ++ + L G+ EI L V+G+ +VA+GS +L+I+ VND+M KGW
Sbjct: 422 GYQRVADDVIAGANELRAGLSEIDGLKVLGEDVSMVVAWGSSDPSLNIYTVNDVMVKKGW 481
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA-NPGPITGGLAPIYGAAGKMP 187
HL+ LQ P ++H+C+T +V V DL AV+ +A G + GG APIYG AG +P
Sbjct: 482 HLSVLQAPPALHMCLTSANVASVRQLCVDLAIAVKETRALGKGKVDGGKAPIYGLAGGLP 541
Query: 186 DRGMVNELLVSFMD 145
DRG V ++L D
Sbjct: 542 DRGTVGDILKDVQD 555
[80][TOP]
>UniRef100_C5DM58 KLTH0G06182p n=1 Tax=Lachancea thermotolerans CBS 6340
RepID=C5DM58_LACTC
Length = 561
Score = 100 bits (250), Expect = 7e-20
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+ + +I+ ++ L++ + E I EL +IG P ++VAF S +D+ E++D ++ +GWH
Sbjct: 419 GYINSCKEIVSTARELKKFIHEEIPELCIIGDPLCSVVAFTSDQIDVHELSDKLAKQGWH 478
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG--PITGGLAPIYGAAGKMP 187
L+ALQ P ++H+ +T P + + +R L+E V+ + + P P + G + +YG AG +
Sbjct: 479 LSALQNPPALHLAVTWLTRPALPELMRTLQEVVKELSSEPNKKPSSDGTSALYGVAGSVK 538
Query: 186 DRGMVNELLVSFMDSQY 136
G+V+ LLV F+D+ Y
Sbjct: 539 TSGVVDRLLVGFLDTLY 555
[81][TOP]
>UniRef100_UPI0001792440 PREDICTED: similar to Sphingosine-1-phosphate lyase CG8946-PA n=1
Tax=Acyrthosiphon pisum RepID=UPI0001792440
Length = 552
Score = 100 bits (249), Expect = 9e-20
Identities = 51/137 (37%), Positives = 85/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ +T ++M+ +EE +R + +F+ GKP +++A GS +I+ ++D ++S+GW+L
Sbjct: 413 GYITSTKEVMDTKIFIEEQLRSMKGIFIFGKPTTSVIAIGSDDFNIYRLSDALNSRGWNL 472
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLR-EAVETVKANPGPITGGLAPIYGAAGKMP 187
N LQ P IHICIT H V F+ DLR E +E +K +TG +A +YG + +P
Sbjct: 473 NTLQFPIGIHICITHLHTKPGVASLFIEDLRQELIEILKTPNVELTGKMA-MYGMSATLP 531
Query: 186 DRGMVNELLVSFMDSQY 136
DR +V ++ F+D+ Y
Sbjct: 532 DRTIVGDITRYFIDAMY 548
[82][TOP]
>UniRef100_A9UYY0 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UYY0_MONBE
Length = 574
Score = 100 bits (249), Expect = 9e-20
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEV-NDIMSSKGWH 361
GY++ T KI++A++ + EG+++I L ++ +PD +V++ S D++ + + ++ GW
Sbjct: 434 GYVKCTQKIIKAAREIAEGIKKIPGLRLMCEPDGPVVSWTSDVFDVYRMTHGLIEEHGWD 493
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
LN LQ P SIHIC+TL H +V+ FL D+ + + ANPG G A +YG A +P
Sbjct: 494 LNVLQFPPSIHICVTLAHTREGIVESFLNDMAKVAAPLFANPGVKAEGGAAVYGMAQSIP 553
Query: 186 DRGMVNELLVSFMDSQY 136
DR ++ +++ +++D+ Y
Sbjct: 554 DRTIIEDVVKTYLDTTY 570
[83][TOP]
>UniRef100_UPI000180C693 PREDICTED: similar to predicted protein n=1 Tax=Ciona intestinalis
RepID=UPI000180C693
Length = 543
Score = 99.8 bits (247), Expect = 2e-19
Identities = 50/136 (36%), Positives = 78/136 (57%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGS--KALDIFEVNDIMSSKGW 364
GY+ K+ME +++++EGVR I L V+G P MT F + ++L IF + D+M KGW
Sbjct: 406 GYIDMARKLMETTEKMKEGVRSIEGLKVLGSPLMTAFGFSTSDESLSIFGIVDVMEEKGW 465
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
+ A + P+S+H I H+ D+++ DL+++VE VK N G + IYG +P
Sbjct: 466 KMEAQRGPDSVHCSILPNHIKSCDEWVSDLKQSVEQVKKNGTNPKNGTSAIYGMLSMVPS 525
Query: 183 RGMVNELLVSFMDSQY 136
G+V+ LV D Y
Sbjct: 526 DGIVDNFLVDLFDEIY 541
[84][TOP]
>UniRef100_UPI00015B42F4 PREDICTED: similar to sphingosine phosphate lyase n=1 Tax=Nasonia
vitripennis RepID=UPI00015B42F4
Length = 567
Score = 99.8 bits (247), Expect = 2e-19
Identities = 45/136 (33%), Positives = 84/136 (61%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T I++ ++ +E +R ++ ++V G P +++A GS +I+ ++ ++++GW+L
Sbjct: 404 GYVKATKDIIDTTQYIERELRGMNNIYVFGTPMTSVIAVGSHDFEIYRLSQALNARGWNL 463
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
N LQ P++IHIC+T H V F+ D+R +E + P G+ +YG+A +PD
Sbjct: 464 NTLQFPSAIHICVTHVHTEPGVAQQFVDDVRFELEKIMQTPKEEAEGIYALYGSAQTIPD 523
Query: 183 RGMVNELLVSFMDSQY 136
R +V ++ SF+DS Y
Sbjct: 524 RSVVGDITKSFIDSMY 539
[85][TOP]
>UniRef100_Q0CJA5 Putative uncharacterized protein n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CJA5_ASPTN
Length = 565
Score = 99.8 bits (247), Expect = 2e-19
Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 15/149 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
GYLQ ++I+ +K + +R ELFV+G P +++VAFG++ LD++ + D M +K
Sbjct: 416 GYLQACTQIVGTAKEIATAIRTNPLLASELFVLGNPLVSVVAFGARHLDVYRIADGMLNK 475
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKAN-----------PGPITGG 223
GWHLNA+Q P +IH+ +T+ V V + DL V++ + P P TG
Sbjct: 476 GWHLNAMQDPPAIHVAVTMPIVKVWMRLIADLEAVVQSERKEVEKRLEAGESIPEP-TGN 534
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++G+V EL F+D Y
Sbjct: 535 SATLYGVAGSLPNKGIVVELTRGFLDLLY 563
[86][TOP]
>UniRef100_A8N7P6 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N7P6_COPC7
Length = 569
Score = 99.8 bits (247), Expect = 2e-19
Identities = 55/140 (39%), Positives = 84/140 (60%), Gaps = 6/140 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIMSSKG 367
GYL++ I+ ++++ + + I EL+V+G P ++VAFGSK +++ EV D MS KG
Sbjct: 431 GYLESCRAIVLGARQIADAITSSIPELYVLGDPPASVVAFGSKHPNVNVLEVGDAMSKKG 490
Query: 366 WHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM- 190
WHLN L P ++HI +T VP+VD F+ DL++AV K +P G + +YG
Sbjct: 491 WHLNGLSGPPAVHIAVTRLTVPLVDQFIADLKDAVREAKVSPSG-QGTMVALYGLGNSSA 549
Query: 189 --PDRGMVNELLVSFMDSQY 136
PD MV EL +F+D+ Y
Sbjct: 550 VGPD--MVGELATAFLDALY 567
[87][TOP]
>UniRef100_A2QJ87 Contig An04c0180, complete genome n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QJ87_ASPNC
Length = 636
Score = 99.0 bits (245), Expect = 3e-19
Identities = 57/151 (37%), Positives = 85/151 (56%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+++ IM A+K+ E ++E L ++GKP +++VAF SK A+DI+++ D +
Sbjct: 484 SGYIKSCLDIMGAAKKFESSIKEHPVLSKSLDIVGKPMVSVVAFYSKNDAVDIYDIADSL 543
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGP----------IT 229
S+KGWHLNALQ P +IH+ T+ VD DL AVE A
Sbjct: 544 SAKGWHLNALQSPPAIHVAFTVPTAAAVDALTTDLVVAVEAELAKAEERKQQGKSYVVKR 603
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG MPD+ +V+ L F+D+ Y
Sbjct: 604 GDTAALYGVAGSMPDKSIVSRLAEGFLDTLY 634
[88][TOP]
>UniRef100_C9SKG3 Sphingosine-1-phosphate lyase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9SKG3_9PEZI
Length = 566
Score = 98.6 bits (244), Expect = 3e-19
Identities = 52/149 (34%), Positives = 85/149 (57%), Gaps = 15/149 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREI----HELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
GY+ KI+ +K++ E + E+ EL ++G+P ++++AF ++ LDI+++ D MS+K
Sbjct: 416 GYVDACVKIVGTTKKMIERIHEVPALESELEIVGRPLVSVMAFTARNLDIYDIADAMSTK 475
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-----------KANPGPITGG 223
GWHLNALQ P +IH+ +TL V + + DL VE K G G
Sbjct: 476 GWHLNALQNPPAIHVAVTLPITKVWEKLMADLEAVVEAEREKERVRIVEGKGAKGTAKGD 535
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V +L+ F+D Y
Sbjct: 536 SAALYGVAGSLPNKSVVVDLVNGFLDLLY 564
[89][TOP]
>UniRef100_B5VGH2 YDR294Cp-like protein n=1 Tax=Saccharomyces cerevisiae AWRI1631
RepID=B5VGH2_YEAS6
Length = 457
Score = 98.6 bits (244), Expect = 3e-19
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ A+ + ++ ++E I +L ++G P ++++F SK L+I E++D +S KGWH
Sbjct: 310 GYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWH 369
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK--ANPGPITGGLAPIYGAAGKMP 187
NALQ+P ++H+ T VVD+ LR V+ +K +N P G + +YG AG +
Sbjct: 370 FNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVK 429
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++L+V F+D+ Y
Sbjct: 430 TAGVADKLIVGFLDALY 446
[90][TOP]
>UniRef100_B3LG01 Dihydrosphingosine phosphate lyase n=1 Tax=Saccharomyces cerevisiae
RM11-1a RepID=B3LG01_YEAS1
Length = 589
Score = 98.6 bits (244), Expect = 3e-19
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ A+ + ++ ++E I +L ++G P ++++F SK L+I E++D +S KGWH
Sbjct: 442 GYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWH 501
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK--ANPGPITGGLAPIYGAAGKMP 187
NALQ+P ++H+ T VVD+ LR V+ +K +N P G + +YG AG +
Sbjct: 502 FNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVK 561
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++L+V F+D+ Y
Sbjct: 562 TAGVADKLIVGFLDALY 578
[91][TOP]
>UniRef100_A6ZYP2 Dihydrosphingosine phosphate lyase n=1 Tax=Saccharomyces cerevisiae
YJM789 RepID=A6ZYP2_YEAS7
Length = 589
Score = 98.6 bits (244), Expect = 3e-19
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ A+ + ++ ++E I +L ++G P ++++F SK L+I E++D +S KGWH
Sbjct: 442 GYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWH 501
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK--ANPGPITGGLAPIYGAAGKMP 187
NALQ+P ++H+ T VVD+ LR V+ +K +N P G + +YG AG +
Sbjct: 502 FNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVK 561
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++L+V F+D+ Y
Sbjct: 562 TAGVADKLIVGFLDALY 578
[92][TOP]
>UniRef100_Q05567 Sphingosine-1-phosphate lyase n=2 Tax=Saccharomyces cerevisiae
RepID=SGPL_YEAST
Length = 589
Score = 98.6 bits (244), Expect = 3e-19
Identities = 48/137 (35%), Positives = 87/137 (63%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ A+ + ++ ++E I +L ++G P ++++F SK L+I E++D +S KGWH
Sbjct: 442 GYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWH 501
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK--ANPGPITGGLAPIYGAAGKMP 187
NALQ+P ++H+ T VVD+ LR V+ +K +N P G + +YG AG +
Sbjct: 502 FNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVK 561
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++L+V F+D+ Y
Sbjct: 562 TAGVADKLIVGFLDALY 578
[93][TOP]
>UniRef100_Q6CTS1 KLLA0C10505p n=1 Tax=Kluyveromyces lactis RepID=Q6CTS1_KLULA
Length = 582
Score = 98.2 bits (243), Expect = 5e-19
Identities = 48/137 (35%), Positives = 85/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGV-REIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+ + I+ ++ L+E + +EI EL ++G P ++++F S +DI+E++D +S GWH
Sbjct: 438 GYINSCKDIVGKARELKEFIQKEIPELQILGDPLCSVISFTSNKIDIYELSDTLSKSGWH 497
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG--PITGGLAPIYGAAGKMP 187
L+ALQ P+SIH+ +T + VD+ L+ V+ +K +P P + G + +YG AG +
Sbjct: 498 LSALQNPSSIHLALTKLSLKSVDELKHLLKSTVDKMKQSPDAKPSSDGTSALYGVAGSVK 557
Query: 186 DRGMVNELLVSFMDSQY 136
G+ + L+ F+DS Y
Sbjct: 558 TVGVADRLIEGFLDSLY 574
[94][TOP]
>UniRef100_A7TJC3 Putative uncharacterized protein n=1 Tax=Vanderwaltozyma polyspora
DSM 70294 RepID=A7TJC3_VANPO
Length = 583
Score = 98.2 bits (243), Expect = 5e-19
Identities = 44/136 (32%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVR-EIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ A+++L + + E+ EL +IG P ++ AF S +D++E++D ++ +GWH
Sbjct: 425 GYIKSCKEIVSAARKLRKYIENELPELQIIGNPQCSVTAFKSDVIDVYELSDKLAKEGWH 484
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMPD 184
L+ LQ+P ++H+ +T + VD+ L+ +E +K +N P + G + +YG AG +
Sbjct: 485 LSTLQKPAALHLAVTKLSINSVDELCTVLKRNIEEMKESNSTPASDGTSALYGIAGSIKT 544
Query: 183 RGMVNELLVSFMDSQY 136
G+ ++L+V F+DS +
Sbjct: 545 TGVADKLVVGFIDSLF 560
[95][TOP]
>UniRef100_Q2UJL4 Glutamate decarboxylase/sphingosine phosphate lyase n=1
Tax=Aspergillus oryzae RepID=Q2UJL4_ASPOR
Length = 572
Score = 97.8 bits (242), Expect = 6e-19
Identities = 58/152 (38%), Positives = 87/152 (57%), Gaps = 17/152 (11%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELF-----VIGKPDMTIVAFGSK--ALDIFEVNDI 382
+GY+++ I+ A+K+ E +RE H L V+GKP +++VAF SK A+DI+++ D
Sbjct: 420 SGYIKSCLDIVGAAKKFEASIRE-HPLLSKNLDVVGKPMISVVAFQSKNGAVDIYDMADA 478
Query: 381 MSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------TVKANPGPI---- 232
+S+KGWHLNALQ P +IH+ T+ +D DL E VE + G
Sbjct: 479 LSAKGWHLNALQSPAAIHVAFTIPTASALDKLTADLVEVVEKELDKAEERKRQGKSYIIK 538
Query: 231 TGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG MPD+ +V+ L F+D+ Y
Sbjct: 539 RGDTAALYGVAGSMPDKSIVSRLAEGFLDTLY 570
[96][TOP]
>UniRef100_B8N0W9 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Aspergillus
flavus NRRL3357 RepID=B8N0W9_ASPFN
Length = 438
Score = 97.8 bits (242), Expect = 6e-19
Identities = 58/152 (38%), Positives = 87/152 (57%), Gaps = 17/152 (11%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELF-----VIGKPDMTIVAFGSK--ALDIFEVNDI 382
+GY+++ I+ A+K+ E +RE H L V+GKP +++VAF SK A+DI+++ D
Sbjct: 286 SGYIKSCLDIVGAAKKFEASIRE-HPLLSKNLDVVGKPMISVVAFQSKNGAVDIYDMADA 344
Query: 381 MSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------TVKANPGPI---- 232
+S+KGWHLNALQ P +IH+ T+ +D DL E VE + G
Sbjct: 345 LSAKGWHLNALQSPAAIHVAFTIPTASALDKLTADLVEVVEKELDKAEERKRQGKSYIIK 404
Query: 231 TGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG MPD+ +V+ L F+D+ Y
Sbjct: 405 RGDTAALYGVAGSMPDKSIVSRLAEGFLDTLY 436
[97][TOP]
>UniRef100_B8C894 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
RepID=B8C894_THAPS
Length = 203
Score = 97.1 bits (240), Expect = 1e-18
Identities = 53/135 (39%), Positives = 81/135 (60%), Gaps = 3/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIMSSKG 367
GYL T I++ ++ ++ G+R+ I L VIG P ++VAF S L+I+ + M+ KG
Sbjct: 65 GYLDITEGIIKTARAIKRGIRDGIDGLEVIGDPLSSVVAFRSTVPTLNIYGIGQAMTHKG 124
Query: 366 WHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
W+LN+LQ P+ +HIC T H FL DLR+AV VK++P + G A IYG A +P
Sbjct: 125 WNLNSLQYPSCLHICCTNLHRGKDKQFLNDLRDAVHEVKSHPSKYSQGTAAIYGMAHSLP 184
Query: 186 DRGMVNELLVSFMDS 142
D ++ + F+D+
Sbjct: 185 DSTLLEPIARGFVDA 199
[98][TOP]
>UniRef100_C8Z5K6 Dpl1p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z5K6_YEAST
Length = 589
Score = 97.1 bits (240), Expect = 1e-18
Identities = 47/137 (34%), Positives = 86/137 (62%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY+++ +I+ + + ++ ++E I +L ++G P ++++F SK L+I E++D +S KGWH
Sbjct: 442 GYIESCQEIVGVAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWH 501
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK--ANPGPITGGLAPIYGAAGKMP 187
NALQ+P ++H+ T VVD+ LR V+ +K +N P G + +YG AG +
Sbjct: 502 FNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVK 561
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++L+V F+D+ Y
Sbjct: 562 TAGVADKLIVGFLDALY 578
[99][TOP]
>UniRef100_C5PGG5 Sphingosine-1-phosphate lyase, putative n=1 Tax=Coccidioides
posadasii C735 delta SOWgp RepID=C5PGG5_COCP7
Length = 565
Score = 97.1 bits (240), Expect = 1e-18
Identities = 53/151 (35%), Positives = 84/151 (55%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY + +I+ A+K+ E +RE +L VIG+P +++VAF + +DI+++ D M
Sbjct: 413 SGYKDSCHQIVSAAKKFETSIREDPVLSRDLKVIGEPMVSVVAFATTTAEIDIYDIADAM 472
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P ++H+ T+ VD DL E VE +A
Sbjct: 473 SAKGWHLNALQNPAAMHVAFTVPTANAVDQLTADLTEVVEIKRAKADERKRLGQKVEKER 532
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 533 GDTSALYGVAGSIPDKSIVSRLAEGFLDTLY 563
[100][TOP]
>UniRef100_B0D1E7 Predicted protein n=1 Tax=Laccaria bicolor S238N-H82
RepID=B0D1E7_LACBS
Length = 564
Score = 97.1 bits (240), Expect = 1e-18
Identities = 55/140 (39%), Positives = 83/140 (59%), Gaps = 6/140 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE-IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIMSSKG 367
GYL + I+ A++ + + E I EL+V+G P ++VAFGSK +++ EV D MS +G
Sbjct: 426 GYLDSCRSIVLAARTIANAITETIPELYVLGDPPASVVAFGSKHPNVNVLEVGDAMSLRG 485
Query: 366 WHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM- 190
WHLN L P ++HI T +PVVD F+ DL++AV K +P +G + +YG
Sbjct: 486 WHLNGLSDPPAVHIACTRLTLPVVDAFIADLKDAVREAKVSPSG-SGTMVAVYGLGNSSA 544
Query: 189 --PDRGMVNELLVSFMDSQY 136
PD MV +L +F+D+ Y
Sbjct: 545 VGPD--MVGQLATAFLDALY 562
[101][TOP]
>UniRef100_Q1E7L0 Putative uncharacterized protein n=1 Tax=Coccidioides immitis
RepID=Q1E7L0_COCIM
Length = 572
Score = 96.7 bits (239), Expect = 1e-18
Identities = 53/151 (35%), Positives = 84/151 (55%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY + +I+ A+K+ E +RE +L VIG+P +++VAF + +DI+++ D M
Sbjct: 420 SGYKDSCHQIVSAAKKFETSIREDPVLSRDLKVIGEPMVSVVAFATTTAEIDIYDIADAM 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P ++H+ T+ VD DL E VE +A
Sbjct: 480 SAKGWHLNALQNPAAMHVAFTVPTANAVDHLTADLTEVVEIERAKADERKRLGQKVEKER 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 540 GDTSALYGVAGSIPDKSIVSRLAEGFLDTLY 570
[102][TOP]
>UniRef100_B2B105 Predicted CDS Pa_3_7920 n=1 Tax=Podospora anserina
RepID=B2B105_PODAN
Length = 570
Score = 96.7 bits (239), Expect = 1e-18
Identities = 56/150 (37%), Positives = 83/150 (55%), Gaps = 16/150 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREI-----HELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
GYLQ+ +I+ A+K+L + EL ++G P ++++AF SK L+I+++ D MS+
Sbjct: 419 GYLQSCIEIVGATKKLIAHITTTSPVLAQELEILGNPLVSVIAFKSKTLNIYDIADGMSA 478
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKAN-----------PGPITG 226
KGWHLNALQ P +IH+ +TL V V + DL VE K G G
Sbjct: 479 KGWHLNALQNPPAIHVALTLPIVKVWEKLAADLEAVVEQEKEKERARVAEGKGAKGKEVG 538
Query: 225 GLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V EL F+D Y
Sbjct: 539 DSAALYGVAGSLPNKSVVVELARGFLDILY 568
[103][TOP]
>UniRef100_A0DUU2 Chromosome undetermined scaffold_65, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0DUU2_PARTE
Length = 546
Score = 96.3 bits (238), Expect = 2e-18
Identities = 46/134 (34%), Positives = 82/134 (61%), Gaps = 3/134 (2%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKA-LDIFEVNDIMSSKGWHL 358
Y + + +I+ A+ +L + + EI EL V G+P + V F SK ++++ ++ I++SKGW+L
Sbjct: 409 YAELSKQIINATIQLAKQINEIPELEVCGQPRINCVCFKSKGNINVYSIHQILTSKGWNL 468
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPIT--GGLAPIYGAAGKMPD 184
N Q PN IHI +T Q++ + F+++++EA++ +KANP G + +YG K+PD
Sbjct: 469 NTTQNPNGIHISVTQQNIQNLKQFVQEIKEAIQEIKANPSQYKKGGDMGALYGTTQKIPD 528
Query: 183 RGMVNELLVSFMDS 142
L ++DS
Sbjct: 529 SKFAGNALKLYLDS 542
[104][TOP]
>UniRef100_Q2GNQ0 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
RepID=Q2GNQ0_CHAGB
Length = 570
Score = 96.3 bits (238), Expect = 2e-18
Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 17/152 (11%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
TGYL++ ++I+ A+KRL ++ EL ++G P +++VAF +++L+I++V D MS+
Sbjct: 417 TGYLKSCTQIVGATKRLLSHIQTHPTLSTELEILGNPLVSVVAFRARSLNIYDVADAMSA 476
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLR------------EAVETVKANPG-PI 232
+GWHLNALQ P +IH+ +TL V V + DL VE K G +
Sbjct: 477 RGWHLNALQDPPAIHVAVTLPIVKVWERLAADLEAVVDAEREKERARQVEGKKTRGGEAV 536
Query: 231 TGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
TG A +YG AG +P++ +V +L F+D Y
Sbjct: 537 TGDAAALYGVAGSLPNKSVVVDLASGFLDLLY 568
[105][TOP]
>UniRef100_C5E100 ZYRO0G16918p n=1 Tax=Zygosaccharomyces rouxii CBS 732
RepID=C5E100_ZYGRC
Length = 570
Score = 96.3 bits (238), Expect = 2e-18
Identities = 45/137 (32%), Positives = 84/137 (61%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGV-REIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
GY ++ +I+ A+++L+ + +E+ EL +IG P +V+F S L+++E+ D +S GWH
Sbjct: 427 GYTDSSREIITAARKLKSSIAKELPELQIIGDPLCCVVSFKSDQLNVYELGDKLSKMGWH 486
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG--PITGGLAPIYGAAGKMP 187
L+ALQ+P ++HI +T V +D + DL+ V +K NP P G + +YG A +
Sbjct: 487 LSALQKPPALHIAVTKLSVSSIDKLVSDLKTMVNEMKKNPNQKPANDGTSALYGVASSIK 546
Query: 186 DRGMVNELLVSFMDSQY 136
G+ ++++ ++D+ Y
Sbjct: 547 TTGVADKVVAGYLDTLY 563
[106][TOP]
>UniRef100_A4RSX4 Sphingosine-1-phosphate lyase n=1 Tax=Ostreococcus lucimarinus
CCE9901 RepID=A4RSX4_OSTLU
Length = 532
Score = 95.9 bits (237), Expect = 2e-18
Identities = 52/133 (39%), Positives = 83/133 (62%), Gaps = 2/133 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGS--KALDIFEVNDIMSSKGW 364
GY + +I+E++ +L + V + L +IG+ +VA+ + + +++ +NDI+SSKGW
Sbjct: 395 GYSRVAHEIIESAIKLRKAVADTDGLELIGRHATMVVAWRTTDRTNNVYVLNDILSSKGW 454
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
L LQ P+++H CIT ++ VD + DL++AV+T + I GG APIYG A +PD
Sbjct: 455 RLAVLQNPSALHFCITPANISSVDALIDDLKQAVQTSR-TLDKIPGGKAPIYGLAHGLPD 513
Query: 183 RGMVNELLVSFMD 145
RG+V ELL D
Sbjct: 514 RGVVKELLRDIQD 526
[107][TOP]
>UniRef100_Q5BZ75 SJCHGC05403 protein (Fragment) n=1 Tax=Schistosoma japonicum
RepID=Q5BZ75_SCHJA
Length = 207
Score = 95.5 bits (236), Expect = 3e-18
Identities = 47/141 (33%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVN----DIMSS 373
+GY ++T +I+ ++ + + +R+I + ++G+P+++IVAFGS +I+++ D +
Sbjct: 61 SGYCKSTKRIISTTRYITDELRKIPGINILGQPNVSIVAFGSNNFNIYKLGHALLDKPNG 120
Query: 372 KGWHLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAA 199
+GW+LN LQ P +IH C+T H D F+ D++EAV+ + P G A +YG +
Sbjct: 121 RGWNLNNLQFPPAIHFCVTDMHTVKGCADKFIHDVKEAVKELMKTPNTKPEGSAALYGLS 180
Query: 198 GKMPDRGMVNELLVSFMDSQY 136
+PDR +V EL ++D+ Y
Sbjct: 181 HMIPDRSIVEELAHCYLDAYY 201
[108][TOP]
>UniRef100_C4JRQ4 Sphingosine-1-phosphate lyase n=1 Tax=Uncinocarpus reesii 1704
RepID=C4JRQ4_UNCRE
Length = 571
Score = 95.1 bits (235), Expect = 4e-18
Identities = 52/151 (34%), Positives = 84/151 (55%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY + +I+ A+K+ E +RE +L V+G+P +++VAF + +DI+++ D M
Sbjct: 419 SGYKDSCHQIVGAAKKFEASIREDPVLSRDLKVVGEPMVSVVAFAATTAEIDIYDIADAM 478
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P ++H+ T+ VD DL E VE +A
Sbjct: 479 SAKGWHLNALQNPPAMHVAFTIPTANAVDKLTTDLVEVVELERAKADERRRLGQKVEKER 538
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 539 GDTSALYGVAGSIPDKSIVSRLAEGFLDTLY 569
[109][TOP]
>UniRef100_B7PHK6 Sphingosine phosphate lyase, putative n=1 Tax=Ixodes scapularis
RepID=B7PHK6_IXOSC
Length = 475
Score = 94.7 bits (234), Expect = 5e-18
Identities = 48/118 (40%), Positives = 73/118 (61%), Gaps = 3/118 (2%)
Frame = -1
Query: 480 VREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMS-SKGWHLNALQRPNSIHICITLQHV 304
V E+ ++VIG PD ++VA GS DIF++ + ++ +GW+LN LQ P H+C+TL HV
Sbjct: 350 VSEVPGIYVIGSPDTSVVAIGSHVFDIFQLMEKLTHQRGWNLNPLQYPAGFHLCVTLLHV 409
Query: 303 P--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
V D F+ D+RE + +P + G A IYG A +PDR +V +L +++DS Y
Sbjct: 410 SEKVADRFVNDVRELTAEIMKDPPKPSTGQAAIYGMAQSLPDRTVVEDLARAYIDSCY 467
[110][TOP]
>UniRef100_C7YZN5 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YZN5_NECH7
Length = 571
Score = 94.7 bits (234), Expect = 5e-18
Identities = 49/149 (32%), Positives = 84/149 (56%), Gaps = 14/149 (9%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH---ELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
TGY++ + I+ +K++ ++ EL ++GKP +++VAF ++ L+++++ D MS+K
Sbjct: 421 TGYIEACTNIVGTAKKIANAIQSTPLGGELEILGKPLVSVVAFTARNLNVYDIADGMSAK 480
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-----------KANPGPITGG 223
GWHLNALQ P +IH+ +TL V + + DL VE K G G
Sbjct: 481 GWHLNALQNPPAIHVAVTLPITKVWEKLIADLEAVVEEEREKERVRIVEGKTAHGKAMGD 540
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
+ +YG AG +P++ +V +L F+D Y
Sbjct: 541 TSALYGVAGSLPNKSVVVDLATGFLDLLY 569
[111][TOP]
>UniRef100_C6H2K0 Sphingosine-1-phosphate lyase n=1 Tax=Ajellomyces capsulatus H143
RepID=C6H2K0_AJECH
Length = 573
Score = 94.7 bits (234), Expect = 5e-18
Identities = 53/151 (35%), Positives = 84/151 (55%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY+ +IM A++ E+ +RE L VIGKP +++VA+ S +DI+++ D +
Sbjct: 421 SGYIDCCHQIMAAARTFEQAIREHPALSTALAVIGKPSVSVVAWQSATPEIDIYDIADAL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P +IH+ T+ V+ + DL VE KA
Sbjct: 481 SAKGWHLNALQTPPAIHVAFTVPTAAAVEKLIADLVAVVEQEKAKVAERKKLGLKVEKER 540
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G ++ +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 541 GDVSALYGVAGSIPDKSIVSRLAEGFLDTLY 571
[112][TOP]
>UniRef100_B8LWR8 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Talaromyces
stipitatus ATCC 10500 RepID=B8LWR8_TALSN
Length = 574
Score = 94.7 bits (234), Expect = 5e-18
Identities = 57/151 (37%), Positives = 83/151 (54%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY + +IM A+K+ E +RE L VIGKP++++VAF SK +D +++ D M
Sbjct: 422 SGYTASCHQIMGAAKQFETAIREDPILSANLEVIGKPEVSVVAFASKNVGIDTYDIADAM 481
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--ETVKANP--------GPIT 229
S+KGWHLNALQ P +IH+ T V+ +L E V E KA
Sbjct: 482 SAKGWHLNALQDPPAIHMAFTRPTALAVEKLQTELTEVVSAELAKAEERQRQGKSYAKQR 541
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 542 GDTAALYGVAGSLPDKSIVSRLAEGFLDALY 572
[113][TOP]
>UniRef100_UPI000023DDAA hypothetical protein FG04413.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023DDAA
Length = 572
Score = 94.4 bits (233), Expect = 6e-18
Identities = 49/150 (32%), Positives = 85/150 (56%), Gaps = 15/150 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH----ELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
+GY+ + +KI+ +K++ E ++ EL ++GKP +++VAF ++ L+++++ D M +
Sbjct: 421 SGYIDSCTKIVGTAKKIAEAIQTTPALGGELEIMGKPLVSVVAFTARNLNVYDIADGMGT 480
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-----------KANPGPITG 226
KGWHLNALQ P +IH+ +TL V + + DL VE K G G
Sbjct: 481 KGWHLNALQSPPAIHVAVTLPITKVWEKLITDLEAVVEEEREKERVRLVEGKGTHGKAMG 540
Query: 225 GLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
+ +YG AG +P++ +V +L F+D Y
Sbjct: 541 DASALYGVAGSLPNKSVVVDLASGFLDLLY 570
[114][TOP]
>UniRef100_B7G9X7 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
1055/1 RepID=B7G9X7_PHATR
Length = 442
Score = 94.4 bits (233), Expect = 6e-18
Identities = 48/132 (36%), Positives = 78/132 (59%), Gaps = 1/132 (0%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + I+ A++ + +G++ + + ++ +V+F S +DI+ + D M+ GW+L
Sbjct: 307 GYRERSHLIVNAARAIADGIQLVRGVKLLTPKPFMVVSFTSNEMDIYRIQDYMTKAGWNL 366
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMPDR 181
NALQ P S+HIC+TL VP VD FLRDL+ ++ V+ G G A +YG G +P
Sbjct: 367 NALQSPASVHICVTLNVVPKVDSFLRDLKMSINQVRNEGKGGRKKGTAGVYGTVGSLP-A 425
Query: 180 GMVNELLVSFMD 145
G V+ L +F D
Sbjct: 426 GPVDYSLRAFTD 437
[115][TOP]
>UniRef100_A1CHZ0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Aspergillus
clavatus RepID=A1CHZ0_ASPCL
Length = 572
Score = 94.4 bits (233), Expect = 6e-18
Identities = 54/151 (35%), Positives = 86/151 (56%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+ + +I+ A+K+ E ++E L V+GKP +++VAF S+ A+DI++V D +
Sbjct: 420 SGYINSCLEIIGAAKKFEASIKEHPVLSKNLTVVGKPMVSVVAFQSQNGAIDIYDVADGL 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------TVKANPGPI----T 229
S+KGWHLNALQ P +IH+ T+ V+ DL + VE + G
Sbjct: 480 SAKGWHLNALQSPPAIHVAFTIPTAAAVEKLTSDLVDTVEKELEKAEERRRQGKAYVLKR 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +VN L F+D+ Y
Sbjct: 540 GDTSALYGVAGSIPDKSIVNRLAEGFLDTLY 570
[116][TOP]
>UniRef100_Q08TY4 Sphingosine-1-phosphate lyase 1 n=1 Tax=Stigmatella aurantiaca
DW4/3-1 RepID=Q08TY4_STIAU
Length = 440
Score = 94.0 bits (232), Expect = 8e-18
Identities = 45/134 (33%), Positives = 75/134 (55%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+N +++ A+ L G+ I L V+G P + + AF S +L+++E+ D M ++GW +
Sbjct: 305 GYLENARRVLSATDTLVAGINAIPGLRVLGAPQVGVFAFSSDSLNVYELGDAMEARGWKM 364
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRG 178
+ Q P ++H IT H +V+ L DLR+ + A P G A +YG G +PD
Sbjct: 365 DRQQNPPALHCMITPSHERIVEPLLADLRDCASKLAAGE-PAPEGSAAMYGMVGAIPDSK 423
Query: 177 MVNELLVSFMDSQY 136
V+ L+ F+D +
Sbjct: 424 QVDGFLLEFLDGVF 437
[117][TOP]
>UniRef100_C0NMW5 Sphingosine-1-phosphate lyase n=1 Tax=Ajellomyces capsulatus G186AR
RepID=C0NMW5_AJECG
Length = 573
Score = 94.0 bits (232), Expect = 8e-18
Identities = 53/151 (35%), Positives = 83/151 (54%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY+ +IM A++ E+ +RE L VIGKP +++VA+ S +DI+++ D +
Sbjct: 421 SGYIDCCHQIMAAARTFEQAIREHPALSTALAVIGKPSVSVVAWQSATPEIDIYDIADAL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P +IH+ T+ V+ + DL VE KA
Sbjct: 481 SAKGWHLNALQTPPAIHVAFTVPTAAAVEKLIADLVAVVEQEKAKVAERKKLGLKVEKER 540
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 541 GDASALYGVAGSIPDKSIVSRLAEGFLDTLY 571
[118][TOP]
>UniRef100_B0Y6N4 Sphinganine-1-phosphate aldolase BST1, putative n=2 Tax=Aspergillus
fumigatus RepID=B0Y6N4_ASPFC
Length = 572
Score = 94.0 bits (232), Expect = 8e-18
Identities = 54/151 (35%), Positives = 86/151 (56%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
TGY+ + +I+ A+K+ E ++E L ++GKP +++VAF S+ A+DI++V D +
Sbjct: 420 TGYINSCLEIIGAAKKFEASIKEHPVLSKNLGIVGKPMVSVVAFQSQNGAVDIYDVADGL 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------TVKANPGPI----T 229
S+KGWHLNALQ P +IH+ T+ V+ DL E VE + G
Sbjct: 480 SAKGWHLNALQSPPAIHVAFTIPTAAAVEKLTTDLVETVEKELEKAEERKRQGKSYVLKR 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 540 GDTSALYGVAGSLPDKSIVSRLAEGFLDTLY 570
[119][TOP]
>UniRef100_C4QDT2 Sphingosine phosphate lyase, putative n=1 Tax=Schistosoma mansoni
RepID=C4QDT2_SCHMA
Length = 1239
Score = 93.6 bits (231), Expect = 1e-17
Identities = 44/140 (31%), Positives = 85/140 (60%), Gaps = 6/140 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK---- 370
GY ++T +I+ ++ + + +R+I +FV G+P++++VAF S DI++++ +S K
Sbjct: 1095 GYCKSTKRIISTTRYIIDELRKIPGIFVFGEPNVSVVAFSSNNFDIYKLSHSLSDKPNGR 1154
Query: 369 GWHLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAG 196
GW+LN LQ P ++H+C+T H + F++D++E + + P + G +YG +
Sbjct: 1155 GWNLNNLQFPPAVHLCVTDMHTTKGCAERFIQDVKEIAKELMKKPNKKSKGSVALYGLSQ 1214
Query: 195 KMPDRGMVNELLVSFMDSQY 136
+PDR +V EL ++D+ Y
Sbjct: 1215 MIPDRSIVTELAHCYLDAYY 1234
[120][TOP]
>UniRef100_A5DBE5 Putative uncharacterized protein n=1 Tax=Pichia guilliermondii
RepID=A5DBE5_PICGU
Length = 588
Score = 93.2 bits (230), Expect = 1e-17
Identities = 49/140 (35%), Positives = 85/140 (60%), Gaps = 6/140 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE---IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSS 373
GY ++ I+ A+ +L+E ++ L V+G P +++AF SK +++I+++ D +++
Sbjct: 447 GYRESCFDIVTATMKLKEEIKSGKLSQYLEVLGDPIASVIAFKSKNASVNIYDLGDALTA 506
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKAN-PGPITGGLAPIYGAAG 196
KGWH ALQ+P ++H T VP+V++ +RDL E E + AN G A IYG AG
Sbjct: 507 KGWHFAALQKPAALHFAFTRLTVPIVNELIRDLIECTEELAANKSGNKKNDTAAIYGVAG 566
Query: 195 KMPDRGMVNELLVSFMDSQY 136
+ G+ N ++V+F+D+ Y
Sbjct: 567 SVSTSGVANRIIVAFLDALY 586
[121][TOP]
>UniRef100_C8VL65 Putative uncharacterized protein n=2 Tax=Emericella nidulans
RepID=C8VL65_EMENI
Length = 572
Score = 92.8 bits (229), Expect = 2e-17
Identities = 51/151 (33%), Positives = 86/151 (56%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELF----VIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+++ I+ A+K+ E + E L V+G+P ++++AF SK A+DI+++ D +
Sbjct: 420 SGYIKSCLDIVNAAKKFESAINEDARLSPNLQVVGQPMVSVIAFESKNDAVDIYDIADDL 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRD--------LREAVETVKANPGPIT-- 229
S+KGWHLNALQ P ++H+ T+ VD + D L +A E + +
Sbjct: 480 SAKGWHLNALQSPPAMHVAFTIPTAAAVDTLISDLVAVVEKELEKAEERKRQGKSYVVKR 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG MPD+ +V+ L F+D+ Y
Sbjct: 540 GDTSALYGVAGSMPDKSIVSRLAEGFLDTLY 570
[122][TOP]
>UniRef100_B6HST2 Pc22g13200 protein n=1 Tax=Penicillium chrysogenum Wisconsin
54-1255 RepID=B6HST2_PENCW
Length = 572
Score = 92.4 bits (228), Expect = 2e-17
Identities = 55/151 (36%), Positives = 85/151 (56%), Gaps = 17/151 (11%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVR-----EIHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
GY+ + + I+ A+++ E VR +H + VIG P +++VAF SK A+DI+++ D +
Sbjct: 421 GYVNSCTDIINAARKFETAVRTDTTISLH-MEVIGNPIVSVVAFRSKNGAIDIYDIADDL 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--ETVKANPGP--------IT 229
S+KGWHLNALQ P +IH T+ VD + DL E + E KA
Sbjct: 480 SAKGWHLNALQSPAAIHCAFTIPTAKAVDQLIADLSEVIGKELEKAEQRKREGKSYILKR 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 540 GDTSALYGVAGSIPDKSVVSRLAEGFLDTLY 570
[123][TOP]
>UniRef100_A1CWS0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Neosartorya
fischeri NRRL 181 RepID=A1CWS0_NEOFI
Length = 572
Score = 92.4 bits (228), Expect = 2e-17
Identities = 54/151 (35%), Positives = 84/151 (55%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
TGY+ + +I+ A+K+ E + E L ++GKP +++VAF S+ A+DI++V D +
Sbjct: 420 TGYINSCLEIIGAAKKFEASIEEHPVLSKNLGIVGKPMVSVVAFQSQNGAVDIYDVADGL 479
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------TVKANPGPI----T 229
S KGWHLNALQ P +IH+ T+ V+ DL E VE + G
Sbjct: 480 SGKGWHLNALQSPPAIHVAFTIPTAAAVEKLTTDLVETVEKELEKAEERKRQGKSYVLKR 539
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 540 GDTSALYGVAGSIPDKSIVSRLAEGFLDTLY 570
[124][TOP]
>UniRef100_Q0CZH7 Putative uncharacterized protein n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CZH7_ASPTN
Length = 572
Score = 92.0 bits (227), Expect = 3e-17
Identities = 55/150 (36%), Positives = 81/150 (54%), Gaps = 16/150 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMS 376
GY+ + +I+ A+K+ E +RE L V+GKP +++VAF S +D +++ D +S
Sbjct: 421 GYINSCLEIVGAAKKFELSIREHPVLSKNLGVVGKPMVSVVAFESTNPGVDTYDLADGLS 480
Query: 375 SKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGP----------ITG 226
+KGWHLNALQ P +IH+ TL VD DL E +E A G
Sbjct: 481 AKGWHLNALQSPPAIHVAFTLPTAAAVDKLTADLVEVLEKELAKAEERKRQGKSYVIKRG 540
Query: 225 GLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG MPD+ +V+ L F+D+ Y
Sbjct: 541 DTAALYGVAGSMPDKSVVSRLAEGFLDTLY 570
[125][TOP]
>UniRef100_B6QPY0 Sphinganine-1-phosphate aldolase BST1, putative n=1 Tax=Penicillium
marneffei ATCC 18224 RepID=B6QPY0_PENMQ
Length = 574
Score = 92.0 bits (227), Expect = 3e-17
Identities = 55/151 (36%), Positives = 82/151 (54%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+ + +IM A+K+ E +RE L VIG P +++VAF SK +D +++ D M
Sbjct: 422 SGYVASCHQIMGAAKQFETAIREDPILSANLEVIGNPQVSVVAFASKNVGIDTYDIADAM 481
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--ETVKANP--------GPIT 229
S+KGWHLNALQ P +IH+ T V+ +L E V E KA
Sbjct: 482 SAKGWHLNALQDPAAIHVAFTRPTALAVEKLQSELTEVVSAELAKAEERQRQGKSYARQR 541
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 542 GDTSALYGVAGSLPDKSIVSRLAEGFLDTLY 572
[126][TOP]
>UniRef100_A8PYD7 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
7966 RepID=A8PYD7_MALGO
Length = 263
Score = 92.0 bits (227), Expect = 3e-17
Identities = 54/138 (39%), Positives = 86/138 (62%), Gaps = 4/138 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVR-EIHELFVIGKPDMTIVAFGSKA-LDIFEVNDIMSSKGW 364
GY+Q+ +I+ A+K +E+ VR EI EL ++GKP ++++AF S ++I++V D MS +GW
Sbjct: 121 GYIQSCREIVGAAKEIEKRVRAEIPELVILGKPLVSVLAFASAGNVNIYDVGDQMSRRGW 180
Query: 363 HLNALQRP-NSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMP 187
HLNAL + HI T VPVVD F+ DL+E+V ++ P +G +A +YG P
Sbjct: 181 HLNALSGDMPAFHIACTRLTVPVVDRFVHDLKESVAASRSRPSK-SGAMATVYGLHTTTP 239
Query: 186 DRGM-VNELLVSFMDSQY 136
M + E+ ++D+ Y
Sbjct: 240 VAPMLLKEMAARYIDTMY 257
[127][TOP]
>UniRef100_Q01EF2 Putative sphingosine-1-phosphate lyase (ISS) n=1 Tax=Ostreococcus
tauri RepID=Q01EF2_OSTTA
Length = 498
Score = 91.7 bits (226), Expect = 4e-17
Identities = 53/135 (39%), Positives = 76/135 (56%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFG-SKALDIFEVNDIMSSKGWH 361
GY + I +K+L E + L +IG IVA+ S +I+ +NDI++SKGW
Sbjct: 362 GYSKAAHDIFAGAKKLREAIAATEGLELIGTHITMIVAWHTSTGSNIYVLNDILTSKGWR 421
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAV---ETVKANPGPITGGLAPIYGAAGKM 190
L LQ P ++H CIT ++ +D+ + DLR AV +T+K P GG APIYG A +
Sbjct: 422 LAVLQNPKALHFCITPANLSAIDELITDLRSAVRLSQTLKTVP----GGKAPIYGLAHGL 477
Query: 189 PDRGMVNELLVSFMD 145
PDRG++ LL D
Sbjct: 478 PDRGVIKALLKDVQD 492
[128][TOP]
>UniRef100_C5GFQ5 Sphinganine-1-phosphate aldolase BST1 n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GFQ5_AJEDR
Length = 573
Score = 91.3 bits (225), Expect = 6e-17
Identities = 52/153 (33%), Positives = 85/153 (55%), Gaps = 18/153 (11%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY+ + +I+ A++ E+ +RE L V+GKP +++VA+ S +DI+++ D +
Sbjct: 421 SGYIDSCHQIITAARTFEQAIREHPTLSSALKVLGKPMVSVVAWDSATPEIDIYDIADAL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVET------------VKANPGP 235
S+KGWHLNALQ P +IH+ T+ V+ + DL VE +K G
Sbjct: 481 SAKGWHLNALQAPPAIHVAFTVPTAGAVEKLIADLVAVVEQEREKAAERKRLGLKVEKG- 539
Query: 234 ITGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG +PD+ +V+ L F+D+ Y
Sbjct: 540 -KGDAAALYGVAGSIPDKSIVSRLAEGFLDTLY 571
[129][TOP]
>UniRef100_UPI000151AD88 hypothetical protein PGUG_00600 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151AD88
Length = 588
Score = 90.1 bits (222), Expect = 1e-16
Identities = 48/140 (34%), Positives = 83/140 (59%), Gaps = 6/140 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE---IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIMSS 373
GY ++ I+ A+ +L+E ++ L V+G P ++AF K +++I+++ D +++
Sbjct: 447 GYRESCFDIVTATMKLKEEIKSGKLSQYLEVLGDPIALVIAFKLKNASVNIYDLGDALTA 506
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKAN-PGPITGGLAPIYGAAG 196
KGWH ALQ+P ++H T VP+V++ +RDL E E + AN G A IYG AG
Sbjct: 507 KGWHFAALQKPAALHFAFTRLTVPIVNELIRDLIECTEELAANKSGNKKNDTAAIYGVAG 566
Query: 195 KMPDRGMVNELLVSFMDSQY 136
+ G+ N ++V+F+D+ Y
Sbjct: 567 SVSTSGVANRIIVAFLDALY 586
[130][TOP]
>UniRef100_A0D650 Chromosome undetermined scaffold_39, whole genome shotgun sequence
n=1 Tax=Paramecium tetraurelia RepID=A0D650_PARTE
Length = 559
Score = 89.7 bits (221), Expect = 2e-16
Identities = 43/135 (31%), Positives = 83/135 (61%), Gaps = 4/135 (2%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKA--LDIFEVNDIMSSKGWH 361
Y++ + KIM+A++ L + + EI E+ V G P + VAF SK L+ + +++I++ +GW
Sbjct: 421 YVEYSKKIMDATQSLAKQLSEIPEIKVFGNPQINCVAFMSKESWLNAYSIHEILTHQGWT 480
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPIT--GGLAPIYGAAGKMP 187
++++Q P +HI +T Q++ + ++ D++ A+E +KANP G + +YG K+P
Sbjct: 481 ISSVQNPAGVHISLTQQNIVNLKQYVHDIKAAIEKIKANPQVYQKGGEMGTLYGTTQKIP 540
Query: 186 DRGMVNELLVSFMDS 142
D + + L ++DS
Sbjct: 541 DSKLAGQALKVYLDS 555
[131][TOP]
>UniRef100_Q5KCC8 Sphinganine-1-phosphate aldolase, putative n=1 Tax=Filobasidiella
neoformans RepID=Q5KCC8_CRYNE
Length = 546
Score = 89.7 bits (221), Expect = 2e-16
Identities = 46/136 (33%), Positives = 76/136 (55%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIH--ELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW 364
GY + +I+ A++ L +R + +L+V+G P +VAF SK ++I+ V D+MS KGW
Sbjct: 410 GYTSSCRQIISAARYLTSSLRTLFPDDLYVLGDPKGPVVAFNSKTINIYAVGDVMSKKGW 469
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
HL+AL +H+ T VD + DL +A++ VKA+P G + +YG
Sbjct: 470 HLSALGGDGGLHMAFTRLSAKSVDKLIEDLGDALKEVKASPQGAGGDMVALYGLGQTSAG 529
Query: 183 RGMVNELLVSFMDSQY 136
+V +L +F+D+ Y
Sbjct: 530 PHVVGKLAETFLDTLY 545
[132][TOP]
>UniRef100_Q55JD1 Putative uncharacterized protein n=1 Tax=Filobasidiella neoformans
RepID=Q55JD1_CRYNE
Length = 546
Score = 89.7 bits (221), Expect = 2e-16
Identities = 46/136 (33%), Positives = 76/136 (55%), Gaps = 2/136 (1%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIH--ELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW 364
GY + +I+ A++ L +R + +L+V+G P +VAF SK ++I+ V D+MS KGW
Sbjct: 410 GYTSSCRQIISAARYLTSSLRTLFPDDLYVLGDPKGPVVAFNSKTINIYAVGDVMSKKGW 469
Query: 363 HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPD 184
HL+AL +H+ T VD + DL +A++ VKA+P G + +YG
Sbjct: 470 HLSALGGDGGLHMAFTRLSAKSVDKLIEDLGDALKEVKASPQGAGGDMVALYGLGQTSAG 529
Query: 183 RGMVNELLVSFMDSQY 136
+V +L +F+D+ Y
Sbjct: 530 PHVVGKLAETFLDTLY 545
[133][TOP]
>UniRef100_A4RHU4 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
RepID=A4RHU4_MAGGR
Length = 567
Score = 88.6 bits (218), Expect = 4e-16
Identities = 52/149 (34%), Positives = 78/149 (52%), Gaps = 15/149 (10%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK 370
GYL +I+ A+K+L + + EL +IGKP ++VAF ++ L+I+++ D M K
Sbjct: 417 GYLAACVEIVGAAKKLVDHINASPSLAAELEIIGKPLSSVVAFRARNLNIYDIADAMGEK 476
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE-----------TVKANPGPITGG 223
GWHLN+LQ P ++H+ TL V + DL VE K G G
Sbjct: 477 GWHLNSLQNPPAMHVAFTLPTAKVWERLATDLEACVEGEREKERARIAEGKGAKGAAVGD 536
Query: 222 LAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG +P++ +V EL F+D Y
Sbjct: 537 SAALYGVAGSLPNKSVVVELANGFLDLLY 565
[134][TOP]
>UniRef100_C1G3V6 Sphingosine-1-phosphate lyase n=1 Tax=Paracoccidioides brasiliensis
Pb18 RepID=C1G3V6_PARBD
Length = 573
Score = 87.4 bits (215), Expect = 8e-16
Identities = 49/151 (32%), Positives = 80/151 (52%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKALDI--FEVNDIM 379
+GY+ + +I+ A++ E+ +RE L +IGKP +++VA+ SK DI +++ D +
Sbjct: 421 SGYVNSCHQIISATRTFEQAIREHPVLSSSLKIIGKPLVSVVAWESKTPDINIYDIADAL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
+ KGWHLNALQ P +H+ T+ V+ + DL VE K
Sbjct: 481 ADKGWHLNALQSPPGMHVAFTVPTAAAVERLVADLVAVVEREKEKVAEQKRMGQKVEKHR 540
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +VN F+D+ Y
Sbjct: 541 GDTSALYGVAGSIPDKSIVNRFAEGFLDTLY 571
[135][TOP]
>UniRef100_C0S546 Sphingosine-1-phosphate lyase n=1 Tax=Paracoccidioides brasiliensis
Pb03 RepID=C0S546_PARBP
Length = 558
Score = 87.4 bits (215), Expect = 8e-16
Identities = 49/151 (32%), Positives = 80/151 (52%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKALDI--FEVNDIM 379
+GY+ + +I+ A++ E+ +RE L +IGKP +++VA+ SK DI +++ D +
Sbjct: 406 SGYVNSCHQIISATRTFEQAIREHPVLSSSLKIIGKPLVSVVAWESKTPDINIYDIADAL 465
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
+ KGWHLNALQ P +H+ T+ V+ + DL VE K
Sbjct: 466 ADKGWHLNALQSPPGMHVAFTVPTAAAVERLVADLVAVVEREKEKVAEQKRMGQKVEKHR 525
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +VN F+D+ Y
Sbjct: 526 GDTSALYGVAGSIPDKSIVNRFAEGFLDTLY 556
[136][TOP]
>UniRef100_A8PQP1 Pyridoxal-dependent decarboxylase conserved domain containing
protein n=1 Tax=Brugia malayi RepID=A8PQP1_BRUMA
Length = 570
Score = 87.0 bits (214), Expect = 1e-15
Identities = 47/137 (34%), Positives = 80/137 (58%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ T I+ A + + G+ + + ++ + D+T VAF ++ L+++ + D M+ GW L
Sbjct: 413 GYVKRTEAIINAVREIRTGIEKCLHIQLLCESDVTTVAFTTRGLNVYALADRMNKLGWVL 472
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGKMP 187
+ LQ P ++HIC+TL H VV++FLR+L A E + +NP A IYG +P
Sbjct: 473 STLQNPPAVHICVTLNHTKSGVVENFLRELNMACEDLVSNPEFSHQSRTAAIYGMVSAVP 532
Query: 186 DRGMVNELLVSFMDSQY 136
D +V E+ ++DS Y
Sbjct: 533 D--LVEEISQMYLDSCY 547
[137][TOP]
>UniRef100_UPI00006CC4BC Pyridoxal-dependent decarboxylase conserved domain containing
protein n=1 Tax=Tetrahymena thermophila
RepID=UPI00006CC4BC
Length = 547
Score = 86.7 bits (213), Expect = 1e-15
Identities = 45/139 (32%), Positives = 77/139 (55%), Gaps = 5/139 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKA---LDIFEVNDIMSS-K 370
G++ T KI++ + + + +R+I EL ++G P TI+AF K ++I+ ++D +
Sbjct: 400 GFMDVTKKIIDGANYIRDEIRKIEELEILGNPVTTIIAFRVKKNQEINIYHISDALKDIN 459
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPIT-GGLAPIYGAAGK 193
W + + P IHI QH+ + + F+ DL++A+ VK NP G A +YG G
Sbjct: 460 DWQVENQRFPECIHISFMPQHLQIKEQFIIDLKKAINIVKENPKKYAKDGTAAMYGMMGM 519
Query: 192 MPDRGMVNELLVSFMDSQY 136
+PD ++ E + FMDS Y
Sbjct: 520 VPDEEVLEEFMAHFMDSVY 538
[138][TOP]
>UniRef100_C5FUQ1 Sphingosine-1-phosphate lyase n=1 Tax=Microsporum canis CBS 113480
RepID=C5FUQ1_NANOT
Length = 574
Score = 86.7 bits (213), Expect = 1e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+ + +I+ A+++ E VR+ L V+G+P +++V F S +DI++V D M
Sbjct: 422 SGYIDSCHQIISAARKFEAAVRKNPGLSSTLEVVGRPMVSVVGFTSTNPEVDIYDVADAM 481
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDL-----REAVETVKANPGPI-----T 229
S+ GWHLNALQ P ++H+ TL VD + DL +E + + I
Sbjct: 482 SNMGWHLNALQSPPAMHVAFTLPTANAVDKLIEDLTTVVQQELTKIAERKAAGIKVEKKR 541
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G + +YG AG +PD+ +V L F+D+ Y
Sbjct: 542 GDTSALYGVAGSIPDKSIVRRLAEGFLDTLY 572
[139][TOP]
>UniRef100_A8XBE1 C. briggsae CBR-SPL-1 protein n=1 Tax=Caenorhabditis briggsae
RepID=A8XBE1_CAEBR
Length = 552
Score = 85.5 bits (210), Expect = 3e-15
Identities = 47/137 (34%), Positives = 86/137 (62%), Gaps = 4/137 (2%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLN 355
Y++ ++I++ ++ L E +++I + G D+++VAF ++I+EV+D M GW+LN
Sbjct: 410 YVRRCAQIVKHTRVLAEKIQKIKWVKPYGSSDVSLVAFSGNGINIYEVSDRMMKLGWNLN 469
Query: 354 ALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKA--NPGPITGGLAPIYGAAGKMP 187
LQ P +IHIC+T+ VV+ F+ DL++ E V A N P G+A +YG A ++P
Sbjct: 470 TLQNPAAIHICLTINQANEEVVNAFVSDLQKTCEDVAAAGNQKP-DHGMAAMYGMAAQVP 528
Query: 186 DRGMVNELLVSFMDSQY 136
+ +V+E++ ++D+ Y
Sbjct: 529 -KSVVDEVIALYIDATY 544
[140][TOP]
>UniRef100_A8Q048 Pyridoxal-dependent decarboxylase conserved domain containing
protein n=1 Tax=Brugia malayi RepID=A8Q048_BRUMA
Length = 557
Score = 84.7 bits (208), Expect = 5e-15
Identities = 45/139 (32%), Positives = 80/139 (57%), Gaps = 4/139 (2%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGV-REIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW 364
+GY+Q T +I++ ++R+ + +I L ++G PD++IVAF S +I+ + D MS+ GW
Sbjct: 409 SGYVQRTREIIKCARRISSAIMNDIDGLRLLGSPDISIVAFTSDVFNIYALVDDMSALGW 468
Query: 363 HLNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPG-PITGGLAPIYGAAGK 193
+LN++Q P HIC+T V F+ DLR+ + +P +A IYG
Sbjct: 469 NLNSIQNPAGAHICVTYNTVLANAWRTFIDDLRKVAFALMNDPDREKYSNMAAIYGLTAN 528
Query: 192 MPDRGMVNELLVSFMDSQY 136
+PD+ +++ L ++D+ Y
Sbjct: 529 IPDKQLISNLAYCYLDACY 547
[141][TOP]
>UniRef100_Q9Y194 Sphingosine-1-phosphate lyase n=1 Tax=Caenorhabditis elegans
RepID=SGPL_CAEEL
Length = 552
Score = 84.3 bits (207), Expect = 7e-15
Identities = 45/136 (33%), Positives = 82/136 (60%), Gaps = 3/136 (2%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLN 355
Y++ ++I++ ++ L E + +I + GK D+++VAF ++I+EV+D M GW+LN
Sbjct: 410 YVRRCAQIVKHTRMLAEKIEKIKWIKPYGKSDVSLVAFSGNGVNIYEVSDKMMKLGWNLN 469
Query: 354 ALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKA-NPGPITGGLAPIYGAAGKMPD 184
LQ P +IHIC+T+ VV+ F DL + E + A G+A +YG A ++P
Sbjct: 470 TLQNPAAIHICLTINQANEEVVNAFAVDLEKICEELAAKGEQKADSGMAAMYGMAAQVP- 528
Query: 183 RGMVNELLVSFMDSQY 136
+ +V+E++ ++D+ Y
Sbjct: 529 KSVVDEVIALYIDATY 544
[142][TOP]
>UniRef100_UPI00003BDB49 hypothetical protein DEHA0D17589g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BDB49
Length = 596
Score = 83.2 bits (204), Expect = 1e-14
Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 10/143 (6%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELF-----VIGKPDMTIVAFG-----SKALDIFEVND 385
Y ++ I+ AS +L+ ++E HE+ VIG P ++VAFG L I+++ +
Sbjct: 453 YAESCRTIVGASMKLKCAIKE-HEMLSKYLEVIGDPIGSVVAFGVTKNYRSTLSIYKIGE 511
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYG 205
+SSKGWH + LQ P ++H +T VPV+ + + DL E + +A +YG
Sbjct: 512 CLSSKGWHFSTLQNPAALHFALTRLTVPVIGELISDLVEVTSAALKDESNSESEIAALYG 571
Query: 204 AAGKMPDRGMVNELLVSFMDSQY 136
AG + G+ ++V+F+D+ Y
Sbjct: 572 VAGSVKTTGVAERVVVAFLDTLY 594
[143][TOP]
>UniRef100_Q8X074 Probable sphingosine-1-phosphate lyase n=1 Tax=Neurospora crassa
RepID=Q8X074_NEUCR
Length = 576
Score = 83.2 bits (204), Expect = 1e-14
Identities = 50/157 (31%), Positives = 84/157 (53%), Gaps = 23/157 (14%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREI----HELFVIGKPDMTIVAFGSKA-LDIFEVNDIMSS 373
GYL++ ++I+ A+K+L E +R EL ++G P ++++AF ++ L+I+++ D MSS
Sbjct: 418 GYLKSCTQIVGATKKLAEHIRSHPTLQQELEILGNPLVSVLAFQARGDLNIYDIADGMSS 477
Query: 372 KGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVE------------------TVKA 247
+GWHLNALQ P +IH+ +T + +DL VE + K
Sbjct: 478 RGWHLNALQNPPAIHVAVTAPVAKNWERLAQDLEGVVEEEREKERVRQVEALKMGISGKT 537
Query: 246 NPGPITGGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG +P++ +V +L F+D Y
Sbjct: 538 GKQKAAGDTAALYGVAGSLPNKSVVVDLARGFLDLLY 574
[144][TOP]
>UniRef100_Q6BRI1 DEHA2D16192p n=1 Tax=Debaryomyces hansenii RepID=Q6BRI1_DEBHA
Length = 596
Score = 83.2 bits (204), Expect = 1e-14
Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 10/143 (6%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIHELF-----VIGKPDMTIVAFG-----SKALDIFEVND 385
Y ++ I+ AS +L+ ++E HE+ VIG P ++VAFG L I+++ +
Sbjct: 453 YAESCRTIVGASMKLKCAIKE-HEMLSKYLEVIGDPIGSVVAFGVTKNYRSTLSIYKIGE 511
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYG 205
+SSKGWH + LQ P ++H +T VPV+ + + DL E + +A +YG
Sbjct: 512 CLSSKGWHFSTLQNPAALHFALTRLTVPVIGELISDLVEVTSAALKDESNSESEIAALYG 571
Query: 204 AAGKMPDRGMVNELLVSFMDSQY 136
AG + G+ ++V+F+D+ Y
Sbjct: 572 VAGSVKTTGVAERVVVAFLDTLY 594
[145][TOP]
>UniRef100_C4R8D3 Dihydrosphingosine phosphate lyase n=1 Tax=Pichia pastoris GS115
RepID=C4R8D3_PICPG
Length = 571
Score = 83.2 bits (204), Expect = 1e-14
Identities = 41/141 (29%), Positives = 78/141 (55%), Gaps = 7/141 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ + I+ +++++ ++ I L +IG P ++VAF S+ I+++ D +S+KGWHL
Sbjct: 429 GYIDSCKLIINTARKIKSEIQSIKGLSIIGDPIGSVVAFTSENYSIYDITDRLSAKGWHL 488
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAV-------ETVKANPGPITGGLAPIYGAA 199
+ LQRP +IHI +T+ V ++ + DL+ + E K A +YG A
Sbjct: 489 STLQRPPAIHIAVTIPTCKVSNELISDLKNIMTEIERDAEDPKIGKKENKNDTAALYGIA 548
Query: 198 GKMPDRGMVNELLVSFMDSQY 136
G + + + ++ +F+D+ Y
Sbjct: 549 GSVKTGPIADRVIEAFLDTMY 569
[146][TOP]
>UniRef100_A6RAW5 Putative uncharacterized protein n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RAW5_AJECN
Length = 593
Score = 83.2 bits (204), Expect = 1e-14
Identities = 49/140 (35%), Positives = 76/140 (54%), Gaps = 16/140 (11%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY+ +IM A++ E+ +RE L VIGKP ++VA+ S +DI+++ D +
Sbjct: 421 SGYIDCCHQIMAAARTFEQAIREHPALSTALAVIGKPMASVVAWQSATPEIDIYDIADAL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG----------PIT 229
S+KGWHLNALQ P +IH+ T+ V+ + DL VE KA
Sbjct: 481 SAKGWHLNALQTPPAIHVAFTVPTAAAVEKLIVDLVAVVEQEKAKVAERKKLGLKVEKER 540
Query: 228 GGLAPIYGAAGKMPDRGMVN 169
G + +YG AG +PD+ +V+
Sbjct: 541 GDASALYGVAGSIPDKSIVS 560
[147][TOP]
>UniRef100_A9UT87 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UT87_MONBE
Length = 456
Score = 81.3 bits (199), Expect = 6e-14
Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Frame = -1
Query: 552 FCCSTGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF--GSKALDIFEVNDIM 379
F GY+ +ME ++ ++ V EI + ++G P MT ++ S +++ + D+M
Sbjct: 316 FLGQEGYMAKAKAVMETTEAIKRAVGEIEGIKILGTPHMTGISIVSASPQINVLILGDMM 375
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAA 199
+GW L Q P+S+H+ I HV V D + DLRE KA+ G+A +YG
Sbjct: 376 EKRGWKLEMQQNPSSLHLSIMPHHVARVQDLVADLRELAMGKKAD----DEGMAAMYGMT 431
Query: 198 GKMPDRGMVNELLVSFMDSQY 136
+PD +V++ L M Y
Sbjct: 432 ANIPDSSIVSDFLAKLMSDVY 452
[148][TOP]
>UniRef100_A8XV29 C. briggsae CBR-TAG-38 protein n=1 Tax=Caenorhabditis briggsae
RepID=A8XV29_CAEBR
Length = 543
Score = 80.9 bits (198), Expect = 7e-14
Identities = 41/139 (29%), Positives = 81/139 (58%), Gaps = 5/139 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKA-LDIFEVNDIMSSKGWH 361
GY N KI++ ++++ +G+ +I + + G D+ IV++ + + ++++ ++ M + W
Sbjct: 401 GYKANAKKIVDTTRKIRDGLSKIKGIKLQGPSDVCIVSWTTDSGVELYRFHNYMKERHWQ 460
Query: 360 LNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITG--GLAPIYGAAGK 193
LN LQ P+ +HI +T+ H + + F+ D + A + V+ NP + A IYG A
Sbjct: 461 LNGLQFPSGVHIMVTMNHTQPGLAESFIADCQAAADFVRQNPVTESDKKSEAAIYGLAQS 520
Query: 192 MPDRGMVNELLVSFMDSQY 136
+PDR +V+E S++D+ Y
Sbjct: 521 IPDRSLVHEFAHSYLDAVY 539
[149][TOP]
>UniRef100_C5M7V2 Sphingosine-1-phosphate lyase n=1 Tax=Candida tropicalis MYA-3404
RepID=C5M7V2_CANTT
Length = 596
Score = 80.9 bits (198), Expect = 7e-14
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 17/151 (11%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELF----VIGKPDMTIVAFGSKA-----LDIFEVND 385
GY + I+ A+ +L+ ++E L +IG P ++VAF + L I+E++D
Sbjct: 444 GYTKFCYDIVSAAMKLKSAIKENPSLAKYLEIIGDPIGSVVAFKVRLDQEDHLSIYEISD 503
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDL--------REAVETVKANPGPIT 229
++S KGWH + LQ P+++H IT VPV+D + DL R A E N
Sbjct: 504 LLSKKGWHFSTLQNPSALHFAITRLTVPVIDQLIEDLAGCTEEAVRIAEEQRNGNIKKKQ 563
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
A +YG AG + G+ + L+ +F+D+ Y
Sbjct: 564 SDTAALYGIAGSVHTAGLADRLIAAFLDTLY 594
[150][TOP]
>UniRef100_Q17456 Temporarily assigned gene name protein 38 n=1 Tax=Caenorhabditis
elegans RepID=Q17456_CAEEL
Length = 542
Score = 79.3 bits (194), Expect = 2e-13
Identities = 44/139 (31%), Positives = 78/139 (56%), Gaps = 5/139 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK-ALDIFEVNDIMSSKGWH 361
GY N KI++ ++++ G+ I + + G D+ IV++ + ++++ ++ M K W
Sbjct: 400 GYKANARKIVDTTRKIRNGLSNIKGIKLQGPSDVCIVSWTTNDGVELYRFHNFMKEKHWQ 459
Query: 360 LNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPITG--GLAPIYGAAGK 193
LN LQ P +HI +T+ H + + F+ D R AVE VK++ + A IYG A
Sbjct: 460 LNGLQFPAGVHIMVTMNHTHPGLAEAFVADCRAAVEFVKSHKPSESDKTSEAAIYGLAQS 519
Query: 192 MPDRGMVNELLVSFMDSQY 136
+PDR +V+E S++D+ Y
Sbjct: 520 IPDRSLVHEFAHSYIDAVY 538
[151][TOP]
>UniRef100_A3LPY6 Dihydrosphingosine-1-phosphate lyase n=1 Tax=Pichia stipitis
RepID=A3LPY6_PICST
Length = 603
Score = 79.3 bits (194), Expect = 2e-13
Identities = 42/147 (28%), Positives = 80/147 (54%), Gaps = 13/147 (8%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELF----VIGKPDMTIVAF------GSKALDIFEVN 388
GY ++ I+ ++ ++++ +R L VIG+P ++++F K ++E+
Sbjct: 455 GYEKSCRDIVSSAMKVKKAIRSDKVLSTYLEVIGEPVASVISFKVKDEYAKKKFSVYELG 514
Query: 387 DIMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK---ANPGPITGGLA 217
DI+ KGWH + LQ P ++H T +P+VD+ L DL +V + N + +A
Sbjct: 515 DILKKKGWHFSTLQHPPALHFAFTKLTIPIVDEMLADLVSSVHELVDHWENSTTPSSDVA 574
Query: 216 PIYGAAGKMPDRGMVNELLVSFMDSQY 136
IYG AG + G+ ++++V+F+D+ Y
Sbjct: 575 TIYGVAGSVRTAGVADKVIVAFLDTLY 601
[152][TOP]
>UniRef100_C4I9Q9 Sphingosine-1-phosphate lyase (SP-lyase)
(SPL)(Sphingosine-1-phosphate aldolase) n=1
Tax=Burkholderia pseudomallei MSHR346 RepID=C4I9Q9_BURPS
Length = 493
Score = 78.6 bits (192), Expect = 4e-13
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 353 GYLARAKAIFETAFDMQAAVRSIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRF 411
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 412 NGLQHPDALHMCVTGPQTQPGVAEQFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468
[153][TOP]
>UniRef100_Q3JJF7 Pyridoxal-dependent decarboxylase conserved domain n=3
Tax=Burkholderia pseudomallei RepID=Q3JJF7_BURP1
Length = 473
Score = 78.6 bits (192), Expect = 4e-13
Identities = 50/120 (41%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 333 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N L+RP+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 392 NGLRRPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448
[154][TOP]
>UniRef100_Q59SV5 Putative uncharacterized protein DPL1 n=1 Tax=Candida albicans
RepID=Q59SV5_CANAL
Length = 589
Score = 78.6 bits (192), Expect = 4e-13
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 17/151 (11%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFG-----SKALDIFEVND 385
GY + I+ AS +++ + L +IG P ++++F S L I+E++D
Sbjct: 437 GYTKFCYDIVSASMKVKRAIETDPILSKHLQIIGDPIGSVISFQLAPQQSGNLSIYEISD 496
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--------ETVKANPGPIT 229
+++ KGWH LQ P+++H T VPVVD+ + DL EA E K
Sbjct: 497 LLTKKGWHFATLQNPSALHFAFTRLTVPVVDELIADLVEATKEAVAIAEEHKKNGVTKAP 556
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG + G+ + L+V+F+D+ Y
Sbjct: 557 GDTAALYGIAGSVHTAGLADRLIVAFLDTLY 587
[155][TOP]
>UniRef100_Q59SR8 Putative uncharacterized protein DPL1 n=1 Tax=Candida albicans
RepID=Q59SR8_CANAL
Length = 589
Score = 78.6 bits (192), Expect = 4e-13
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 17/151 (11%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFG-----SKALDIFEVND 385
GY + I+ AS +++ + L +IG P ++++F S L I+E++D
Sbjct: 437 GYTKFCYDIVSASMKVKRAIETDPILSKHLQIIGDPIGSVISFQLAPQQSGNLSIYEISD 496
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--------ETVKANPGPIT 229
+++ KGWH LQ P+++H T VPVVD+ + DL EA E K
Sbjct: 497 LLTKKGWHFATLQNPSALHFAFTRLTVPVVDELIADLVEATKEAVAIAEEHKKNGVTKAP 556
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG + G+ + L+V+F+D+ Y
Sbjct: 557 GDTAALYGIAGSVHTAGLADRLIVAFLDTLY 587
[156][TOP]
>UniRef100_Q2TW35 Glutamate decarboxylase/sphingosine phosphate lyase n=1
Tax=Aspergillus oryzae RepID=Q2TW35_ASPOR
Length = 566
Score = 78.6 bits (192), Expect = 4e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH----ELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+ + +I+ A+K+ E + + +IG P ++++AF SK ++ +++ D M
Sbjct: 414 SGYISSCRQIVGAAKKFEAAILTNPILKPHIEIIGYPMVSVIAFTSKNDEIETYDIADAM 473
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-------KANPGPIT--- 229
++GWHLNALQ P +IH T+ VD + DL + + + K I
Sbjct: 474 DARGWHLNALQSPPAIHCAFTIPTAEAVDGLISDLIDVISEILLQIQEQKQKGEHIVRQR 533
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG G + DR MVN+ F+D+ Y
Sbjct: 534 GKSAALYGVGGSIADRTMVNQFAEGFLDTLY 564
[157][TOP]
>UniRef100_C4YQC8 Sphingosine-1-phosphate lyase n=1 Tax=Candida albicans
RepID=C4YQC8_CANAL
Length = 589
Score = 78.6 bits (192), Expect = 4e-13
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 17/151 (11%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFG-----SKALDIFEVND 385
GY + I+ AS +++ + L +IG P ++++F S L I+E++D
Sbjct: 437 GYTKFCYDIVSASMKVKRAIETDPILSKHLQIIGDPIGSVISFQLAPQQSGNLSIYEISD 496
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--------ETVKANPGPIT 229
+++ KGWH LQ P+++H T VPVVD+ + DL EA E K
Sbjct: 497 LLTKKGWHFATLQNPSALHFAFTRLTVPVVDELIADLVEATKEAVAIAEEHKKNGVTKAP 556
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG AG + G+ + L+V+F+D+ Y
Sbjct: 557 GDTAALYGIAGSVHTAGLADRLIVAFLDTLY 587
[158][TOP]
>UniRef100_B8NX23 Sphingosine phosphate lyase, putative n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NX23_ASPFN
Length = 566
Score = 78.6 bits (192), Expect = 4e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIH----ELFVIGKPDMTIVAFGSK--ALDIFEVNDIM 379
+GY+ + +I+ A+K+ E + + +IG P ++++AF SK ++ +++ D M
Sbjct: 414 SGYISSCRQIVGAAKKFEAAILTNPILKPHIEIIGYPMVSVIAFTSKNDEIETYDIADAM 473
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETV-------KANPGPIT--- 229
++GWHLNALQ P +IH T+ VD + DL + + + K I
Sbjct: 474 DARGWHLNALQSPPAIHCAFTIPTAEAVDGLISDLIDVISEILLQIQEQKQKGEHIVRQR 533
Query: 228 GGLAPIYGAAGKMPDRGMVNELLVSFMDSQY 136
G A +YG G + DR MVN+ F+D+ Y
Sbjct: 534 GKSAALYGVGGSIADRTMVNQFAEGFLDTLY 564
[159][TOP]
>UniRef100_A5DZL7 Sphingosine-1-phosphate lyase n=1 Tax=Lodderomyces elongisporus
RepID=A5DZL7_LODEL
Length = 584
Score = 78.6 bits (192), Expect = 4e-13
Identities = 47/147 (31%), Positives = 77/147 (52%), Gaps = 13/147 (8%)
Frame = -1
Query: 537 GYLQNTSKI----MEASKRLEEGVREIHELFVIGKPDMTIVAFG-----SKALDIFEVND 385
GY Q+ I ++ K +E+ L +IG P ++V+F K L I+E+ D
Sbjct: 437 GYRQSCFDIVLTMLKVKKAIEKDSTLSEYLEIIGNPIGSVVSFKVKTSKKKELSIYELGD 496
Query: 384 IMSSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDL----REAVETVKANPGPITGGLA 217
+++ KGWH LQ P ++H T PVVD+ + DL +EA+E K G A
Sbjct: 497 LLTKKGWHFATLQNPAALHFAFTRLTTPVVDELIDDLVGCTKEAIELTK-KTGKKQSDTA 555
Query: 216 PIYGAAGKMPDRGMVNELLVSFMDSQY 136
+YG AG + G+ ++++V+F+D+ Y
Sbjct: 556 ALYGIAGSVHTAGLADKIIVAFLDTLY 582
[160][TOP]
>UniRef100_B2HAT7 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
1655 RepID=B2HAT7_BURPS
Length = 493
Score = 77.4 bits (189), Expect = 8e-13
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 353 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRF 411
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 412 NGLQHPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468
[161][TOP]
>UniRef100_A3NNI2 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 668
RepID=A3NNI2_BURP6
Length = 473
Score = 76.6 bits (187), Expect = 1e-12
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 333 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 392 NGLQHPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448
[162][TOP]
>UniRef100_A3P8X5 Sphingosine-1-phosphate lyase n=5 Tax=Burkholderia pseudomallei
RepID=A3P8X5_BURP0
Length = 473
Score = 76.6 bits (187), Expect = 1e-12
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 333 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 392 NGLQHPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448
[163][TOP]
>UniRef100_B1H9D7 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
RepID=B1H9D7_BURPS
Length = 493
Score = 76.6 bits (187), Expect = 1e-12
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 353 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRF 411
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 412 NGLQHPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 468
[164][TOP]
>UniRef100_A4LG68 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 305
RepID=A4LG68_BURPS
Length = 473
Score = 76.6 bits (187), Expect = 1e-12
Identities = 49/120 (40%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 333 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETV--KANPGPITGGLAPIYG--AAG 196
N LQ P+++H+C+T V + F +DL EAVE +A+ P + G +YG AAG
Sbjct: 392 NGLQHPDALHMCVTGPQTQPGVAERFRQDLGEAVEHARHRAHARPQSSG---VYGGDAAG 448
[165][TOP]
>UniRef100_C5JIJ1 Sphinganine-1-phosphate aldolase BST1 n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JIJ1_AJEDS
Length = 569
Score = 75.5 bits (184), Expect = 3e-12
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 18/140 (12%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVRE----IHELFVIGKPDMTIVAFGSKA--LDIFEVNDIM 379
+GY+ + +I+ A++ E+ +RE L V+GKP +++VA+ S +DI+++ D +
Sbjct: 432 SGYIDSCHQIITAARTFEQAIREHPTLSSALKVLGKPMVSVVAWDSATPEIDIYDIADAL 491
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVET------------VKANPGP 235
S+KGWHLNALQ P +IH+ T+ V+ + DL VE +K G
Sbjct: 492 SAKGWHLNALQAPPAIHVAFTVPTAGAVEKLIADLVAVVEQEREKAAERKRLGLKVEKG- 550
Query: 234 ITGGLAPIYGAAGKMPDRGM 175
G A +YG AG + R +
Sbjct: 551 -KGDAAALYGVAGSILIRAL 569
[166][TOP]
>UniRef100_Q585W1 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Trypanosoma brucei RepID=Q585W1_9TRYP
Length = 538
Score = 75.1 bits (183), Expect = 4e-12
Identities = 43/145 (29%), Positives = 74/145 (51%), Gaps = 11/145 (7%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ KI++ R+ + + ++ + +IGKP + AFGS +DIF +N+ + S+GW L
Sbjct: 390 GYVDCCRKIVQTRIRITDALSKLPYIHIIGKPTACVFAFGSNIIDIFVLNEELRSRGWVL 449
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPIT---------GGLAPI 211
N LQ P+ + +TL V D F+ D+ E + A T + I
Sbjct: 450 NCLQFPSGLQFSVTLLQTVGEVADRFIEDVTEIGGRMFAEYEDATKNGRRHGAVNAKSTI 509
Query: 210 YGAAGKMPDRGMVNELLVSFMDSQY 136
YG+ K+ DR ++ ++L F++ Y
Sbjct: 510 YGSQQKVSDRTIIKDVLKEFLNKYY 534
[167][TOP]
>UniRef100_C9ZR31 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Trypanosoma brucei gambiense DAL972
RepID=C9ZR31_TRYBG
Length = 538
Score = 75.1 bits (183), Expect = 4e-12
Identities = 43/145 (29%), Positives = 74/145 (51%), Gaps = 11/145 (7%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ KI++ R+ + + ++ + +IGKP + AFGS +DIF +N+ + S+GW L
Sbjct: 390 GYVDCCRKIVQTRIRITDALSKLPYIHIIGKPTACVFAFGSNIIDIFVLNEELRSRGWVL 449
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVKANPGPIT---------GGLAPI 211
N LQ P+ + +TL V D F+ D+ E + A T + I
Sbjct: 450 NCLQFPSGLQFSVTLLQTVGEVADRFIEDVTEIGGRMFAEYEDATKNGRRHGAVNAKSTI 509
Query: 210 YGAAGKMPDRGMVNELLVSFMDSQY 136
YG+ K+ DR ++ ++L F++ Y
Sbjct: 510 YGSQQKVSDRTIIKDVLKEFLNKYY 534
[168][TOP]
>UniRef100_B9WDX2 Sphingosine-1-phosphate lyase, putative (Sphingosine-1-phosphate
aldolase, putative) (Dihydrosphingosine phosphate lyase,
putative) n=1 Tax=Candida dubliniensis CD36
RepID=B9WDX2_CANDC
Length = 589
Score = 75.1 bits (183), Expect = 4e-12
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Frame = -1
Query: 519 SKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKA-----LDIFEVNDIMSSKGWHLN 355
S M+ + +E L +IG P ++++F L I+E++D+++ KGWH
Sbjct: 447 SAAMKVKRAIENDPILSKHLQIIGDPIGSVISFQLAPQQLGNLSIYEISDLLTKKGWHFA 506
Query: 354 ALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA-----NPGPIT---GGLAPIYGAA 199
LQ P+++H T VPVVD+ + DL +A + A +T G A +YG A
Sbjct: 507 TLQNPSALHFAFTRLTVPVVDELIADLVDATKEAAAIAEEHKKNGVTKPPGDTAALYGIA 566
Query: 198 GKMPDRGMVNELLVSFMDSQY 136
G + G+ + L+V+F+D+ Y
Sbjct: 567 GSVHTAGLADRLIVAFLDTLY 587
[169][TOP]
>UniRef100_A3NNI8 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 668
RepID=A3NNI8_BURP6
Length = 485
Score = 74.7 bits (182), Expect = 5e-12
Identities = 46/135 (34%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 345 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRL 403
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F RDL A + +A+ P T G+ A +
Sbjct: 404 NGLRRPDALQMCVTGPQTQPGVAEQFRRDLGAAADYARAHAQERPKTSGVYASDAAGVDL 463
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 464 SDDARTRAFFTQVID 478
[170][TOP]
>UniRef100_A4LG74 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei 305
RepID=A4LG74_BURPS
Length = 507
Score = 74.7 bits (182), Expect = 5e-12
Identities = 46/135 (34%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 367 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRL 425
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F RDL A + +A+ P T G+ A +
Sbjct: 426 NGLRRPDALQMCVTGPQTQPGVAEQFRRDLGAAADYARAHAQERPKTSGVYASDAAGVDL 485
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 486 SDDARTRAFFTQVID 500
[171][TOP]
>UniRef100_C4M8C7 S phingosine-1-phosphate lyase 1, putative n=1 Tax=Entamoeba
histolytica HM-1:IMSS RepID=C4M8C7_ENTHI
Length = 514
Score = 74.7 bits (182), Expect = 5e-12
Identities = 41/147 (27%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Frame = -1
Query: 561 SVCFCCSTGYLQNTSKIMEASKRLEEGVREIHELFVIG--KPDMTIVAFGSKALDIFEVN 388
S+ F GY+ T I+ SK L+ + ++ + ++ + D +VAF + L+I++V+
Sbjct: 366 SLLFTGKQGYIDATRGILTTSKNLKNELSKMSNIKILNDMEQDTPVVAFTTTDLNIYKVS 425
Query: 387 DIMSSK-GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANP-GPITGGLAP 214
D M+ + W N LQ P ++H C+T + + F+ DL +A++ ++ +P P AP
Sbjct: 426 DCMNKEFQWEFNTLQFPAAVHFCVTEKTIGCEKQFMEDLNKALDIIRKDPKNPKYNVWAP 485
Query: 213 IYGAAGKMPD----RGMVNELLVSFMD 145
+YG +PD MV++++ + D
Sbjct: 486 VYGMTSSLPDIDTLEDMVSQVIAQYCD 512
[172][TOP]
>UniRef100_B0EIY0 Sphingosine-1-phosphate lyase, putative n=1 Tax=Entamoeba dispar
SAW760 RepID=B0EIY0_ENTDI
Length = 514
Score = 74.7 bits (182), Expect = 5e-12
Identities = 41/147 (27%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Frame = -1
Query: 561 SVCFCCSTGYLQNTSKIMEASKRLEEGVREIHELFVIG--KPDMTIVAFGSKALDIFEVN 388
S+ F GY+ T I+ SK L+ + ++ + ++ + D +VAF + L+I++V+
Sbjct: 366 SLLFTGKQGYIDATRGILTTSKNLKNELSKMSNIKILNDMEQDTPVVAFTTTDLNIYKVS 425
Query: 387 DIMSSK-GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANP-GPITGGLAP 214
D M+ + W N LQ P ++H C+T + + F+ DL +A++ ++ +P P AP
Sbjct: 426 DCMNKEFQWEFNTLQFPAAVHFCVTEKTIGCEKQFIEDLNKALDIIRKDPKNPKYNVWAP 485
Query: 213 IYGAAGKMPD----RGMVNELLVSFMD 145
+YG +PD MV++++ + D
Sbjct: 486 VYGMTSSLPDIDTLEDMVSQVIAQYCD 512
[173][TOP]
>UniRef100_A4I5R3 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Leishmania infantum RepID=A4I5R3_LEIIN
Length = 537
Score = 74.7 bits (182), Expect = 5e-12
Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 11/145 (7%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ KI+ + + + ++ + +IG+P ++ AF S +DIF + D + +GW L
Sbjct: 391 GYIDCCHKIVTTRETMTTELSKLPYIRIIGEPTASVFAFTSNVIDIFRLGDDLKLRGWVL 450
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGP-ITGGLAPI-------- 211
N LQ P+ + +TL P V FL D++E +T+ A I G P+
Sbjct: 451 NTLQFPSGLQFSVTLLQTPTAVTARFLSDVKEIGDTLFAESEKLIADGKKPVLGESSGTL 510
Query: 210 YGAAGKMPDRGMVNELLVSFMDSQY 136
YG A ++PDR ++ ++L F+++ Y
Sbjct: 511 YGTAQRVPDRTIIKDVLREFLNTYY 535
[174][TOP]
>UniRef100_A4HIG7 Sphingosine phosphate lyase-like protein,putative n=1
Tax=Leishmania braziliensis RepID=A4HIG7_LEIBR
Length = 537
Score = 74.7 bits (182), Expect = 5e-12
Identities = 45/145 (31%), Positives = 77/145 (53%), Gaps = 11/145 (7%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++ KI+ A + + +R++ + +IG+P ++ AF S +DIF + + + +GW L
Sbjct: 391 GYVECCHKIVLARETMTTELRKLPYIRIIGEPTASVFAFTSSEIDIFLLGEALKLRGWVL 450
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVET--------VKANPGPITG-GLAPI 211
N LQ P + +TL P V FLRD++E T + A PI G + +
Sbjct: 451 NKLQFPCGLQFSVTLLQTPPAVTARFLRDVKEIGATLFAENKKLIAAGKKPIVGESSSTL 510
Query: 210 YGAAGKMPDRGMVNELLVSFMDSQY 136
YG A ++PD +V ++L F+ + Y
Sbjct: 511 YGTAQRIPDGTIVKDVLREFLSTYY 535
[175][TOP]
>UniRef100_UPI00016A8CCF sphingosine-1-phosphate lyase n=1 Tax=Burkholderia oklahomensis
EO147 RepID=UPI00016A8CCF
Length = 473
Score = 73.2 bits (178), Expect = 2e-11
Identities = 46/115 (40%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I + + ++ V I EL V+GKP AF S A DI+ VND M GW
Sbjct: 333 GYLARAQPIFDTAFDIQAAVLAIPELRVLGKPTFCF-AFTSDAFDIYHVNDCMRRHGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVK--ANPGPITGGLAPIYG 205
N LQ P+++H+C+T VV+ F DL EAVE + AN P + G +YG
Sbjct: 392 NGLQHPDALHLCVTGPQTQPGVVERFRDDLGEAVEYARRHANARPKSSG---VYG 443
[176][TOP]
>UniRef100_Q4DT68 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DT68_TRYCR
Length = 545
Score = 73.2 bits (178), Expect = 2e-11
Identities = 43/147 (29%), Positives = 78/147 (53%), Gaps = 13/147 (8%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++N KI+ A ++ + ++ + ++G P ++ AF S+ +DIF + D +S +GW L
Sbjct: 397 GYVENCRKIVNARIKMTAALSKLPYITILGDPITSVFAFNSECIDIFILGDRLSERGWAL 456
Query: 357 NALQRPNSIHICITL--QHVPVVDDFLRD-----------LREAVETVKANPGPITGGLA 217
N LQ P+ + +TL + VVD F++D ++EA + + GG
Sbjct: 457 NRLQFPSGLQFSVTLLQTNEGVVDRFIKDVTSIGEEMYMAVKEAEKEHRVVKKDEAGG-- 514
Query: 216 PIYGAAGKMPDRGMVNELLVSFMDSQY 136
IY + ++ DR +V ++L F+D Y
Sbjct: 515 SIYASQQRVSDRSIVKDILREFLDQYY 541
[177][TOP]
>UniRef100_Q2T8I9 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
E264 RepID=Q2T8I9_BURTA
Length = 473
Score = 72.8 bits (177), Expect = 2e-11
Identities = 43/110 (39%), Positives = 58/110 (52%), Gaps = 4/110 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY I + + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 333 GYRARARAIFDTAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRL 391
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVK--ANPGPITGGL 220
N L+ P+++ +C+T V D F RDL AVE + A P T G+
Sbjct: 392 NGLRHPDALQMCVTEPQTRPGVADQFRRDLGAAVEHARRHARERPKTSGI 441
[178][TOP]
>UniRef100_C5KK69 Sphingosine-1-phosphate lyase, putative n=1 Tax=Perkinsus marinus
ATCC 50983 RepID=C5KK69_9ALVE
Length = 424
Score = 72.8 bits (177), Expect = 2e-11
Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 8/142 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF----GSKALDIFEVNDIMSSK 370
GY ++ I+ A+K LE+G+ +I + V+G+P +++VA G D E +
Sbjct: 282 GYKESCKTIVSAAKHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKT 341
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAV--ETVKANPGPITG--GLAPIYGA 202
W+LN LQ P+ +HIC+T + +D+ L D+ + E K + G +G G A +YG+
Sbjct: 342 HWNLNMLQMPSGVHICVTRLNAEKMDELLTDIEAGLKAEKAKLDAGVKSGHSGNAAVYGS 401
Query: 201 AGKMPDRGMVNELLVSFMDSQY 136
A +P + + + ++ ++D+ Y
Sbjct: 402 AASVP-KELADIVVAKYLDTCY 422
[179][TOP]
>UniRef100_C2AHR3 PLP-dependent enzyme, glutamate decarboxylase n=1
Tax=Thermomonospora curvata DSM 43183 RepID=C2AHR3_THECU
Length = 468
Score = 72.4 bits (176), Expect = 3e-11
Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 9/142 (6%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY KI E S R+++ VR +L ++G+P + +F S DI+ V D M+ +GW
Sbjct: 321 GYRARVKKIFETSARMQQAVRSHPQLRILGEPTF-LFSFTSDEFDIYHVYDFMAGRGWRF 379
Query: 357 NALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVK----ANPGPITGGLAPIYGAA- 199
N Q PN+IH+ +TL V ++F DL EAV + A P +G IYG
Sbjct: 380 NGQQYPNAIHMAVTLPQTRPGVTEEFAADLAEAVAYAQKQHAAGARPHSGA---IYGGVP 436
Query: 198 GKMPDRG--MVNELLVSFMDSQ 139
G + D + +++ +D+Q
Sbjct: 437 GGLTDEADEFIRQIMADMLDAQ 458
[180][TOP]
>UniRef100_UPI00016A8008 sphingosine-1-phosphate lyase n=1 Tax=Burkholderia oklahomensis
C6786 RepID=UPI00016A8008
Length = 473
Score = 71.6 bits (174), Expect = 5e-11
Identities = 45/115 (39%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I + + ++ V I EL V+GKP AF S A DI+ VND M GW
Sbjct: 333 GYLARAQPIFDTAFDMQAAVLAIPELRVLGKPTFCF-AFTSDAFDIYHVNDCMRRHGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVK--ANPGPITGGLAPIYG 205
N LQ P+++H+C+T VV+ F DL EA E + AN P + G +YG
Sbjct: 392 NGLQHPDALHLCVTGPQTQPGVVERFRDDLGEAAEYARRHANARPKSSG---VYG 443
[181][TOP]
>UniRef100_B2HAT2 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
1655 RepID=B2HAT2_BURPS
Length = 485
Score = 71.6 bits (174), Expect = 5e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 345 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRQRGWRL 403
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 404 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 463
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 464 SDDARTRAFFTQVID 478
[182][TOP]
>UniRef100_Q54VR5 Sphingosine-1-phosphate lyase n=1 Tax=Dictyostelium discoideum
RepID=Q54VR5_DICDI
Length = 531
Score = 71.2 bits (173), Expect = 6e-11
Identities = 40/138 (28%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIH--ELFVIGK-PDMTIVAFGSKALDIFEVNDIMSSK- 370
G+++ KIM+ S +++G+ + + +IG P M+I++ SK ++I V D M
Sbjct: 392 GFMEYVDKIMKTSIAIQKGIVSLPLGNVEIIGSNPVMSIISLRSKVVNIHAVADSMEKHF 451
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM 190
W L RPNSIH+ +T H+ + FL +L+ +++ V A+P G A +Y +
Sbjct: 452 SWKLERQHRPNSIHMTLTPSHIGIEKVFLENLKFSIQEVMADPNLSKKGSAAMYNGINNI 511
Query: 189 PDRGMVNELLVSFMDSQY 136
P + ++ L+ F+ Y
Sbjct: 512 PLTAIADDFLIEFLSKTY 529
[183][TOP]
>UniRef100_Q22UE1 Pyridoxal-dependent decarboxylase conserved domain containing
protein n=1 Tax=Tetrahymena thermophila SB210
RepID=Q22UE1_TETTH
Length = 575
Score = 71.2 bits (173), Expect = 6e-11
Identities = 45/138 (32%), Positives = 73/138 (52%), Gaps = 7/138 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVRE---IHELFVIGKPDMTIVAFGSKA---LDIFEVNDIMS 376
GY++ + I K+L + ++E + E+ VIG P +VA K +I+ + +S
Sbjct: 433 GYIEKSKSISGCVKQLVQAIKESPELQEIDVIGNPKTVVVAIVYKKGVNRNIYHLEGALS 492
Query: 375 SKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPI-TGGLAPIYGAA 199
KGW +QRP +IHI IT V D +RDL+ AV+ V NP + IYGA+
Sbjct: 493 QKGWAFAGVQRPAAIHISITHGIANRVKDLIRDLKLAVKEVAENPEKFKNSSSSSIYGAS 552
Query: 198 GKMPDRGMVNELLVSFMD 145
++PD +++ +L +D
Sbjct: 553 VQVPDTRILDSMLEICVD 570
[184][TOP]
>UniRef100_A3P8Y1 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
RepID=A3P8Y1_BURP0
Length = 498
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 358 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 416
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 417 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 476
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 477 SDDARTRAFFTQVID 491
[185][TOP]
>UniRef100_C4I9R5 Sphinganine-1-phosphate aldolase n=1 Tax=Burkholderia pseudomallei
MSHR346 RepID=C4I9R5_BURPS
Length = 485
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 345 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 403
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 404 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 463
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 464 SDDARTRAFFTQVID 478
[186][TOP]
>UniRef100_C0Y786 Putative sphinganine-1-phosphate aldolase n=2 Tax=Burkholderia
pseudomallei RepID=C0Y786_BURPS
Length = 507
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 367 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 425
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 426 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 485
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 486 SDDARTRAFFTQVID 500
[187][TOP]
>UniRef100_B1H9E3 Sphingosine-1-phosphate lyase n=2 Tax=Burkholderia pseudomallei
RepID=B1H9E3_BURPS
Length = 485
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 345 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 403
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 404 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 463
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 464 SDDARTRAFFTQVID 478
[188][TOP]
>UniRef100_Q3JJF3 Pyridoxal-dependent decarboxylase conserved domain n=3
Tax=Burkholderia pseudomallei RepID=Q3JJF3_BURP1
Length = 473
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 333 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 392 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 451
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 452 SDDARTRAFFTQVID 466
[189][TOP]
>UniRef100_A8EMW8 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia pseudomallei
406e RepID=A8EMW8_BURPS
Length = 485
Score = 70.9 bits (172), Expect = 8e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL I E + ++ VR I EL V+GKP AF S A DI+ VND M +GW L
Sbjct: 345 GYLARAKAIFETAFDMQAAVRAIPELRVLGKPTFCF-AFTSDAFDIYHVNDFMRQRGWRL 403
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKAN--PGPITGGLAPIYGAAGKM 190
N L+RP+++ +C+T V + F DL A + +A+ P T G+ A +
Sbjct: 404 NGLRRPDALQMCVTGPQTQPGVAEQFRCDLGAAADYARAHAQERPKTSGVYASDAAGVDL 463
Query: 189 PDRGMVNELLVSFMD 145
D +D
Sbjct: 464 SDDARTRAFFTQVID 478
[190][TOP]
>UniRef100_Q5ZTI6 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
pneumophila subsp. pneumophila str. Philadelphia 1
RepID=SGPL_LEGPH
Length = 601
Score = 70.5 bits (171), Expect = 1e-10
Identities = 43/112 (38%), Positives = 58/112 (51%), Gaps = 5/112 (4%)
Frame = -1
Query: 507 EASKRLEEGVREIHE-LFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSI 331
E + LEEG E ++V G P +I+ F S + + D + +GW LN LQ P+
Sbjct: 440 ELTTLLEEGNGLTSEDIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGF 499
Query: 330 HICITLQHVPV---VDDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMP 187
H+C+T H V F++DLREAV VK PG G +YGA G MP
Sbjct: 500 HLCLTHVHTLVKGFETQFIKDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551
[191][TOP]
>UniRef100_A5IDX4 Sphingosine-1-phosphate lyase I n=1 Tax=Legionella pneumophila str.
Corby RepID=A5IDX4_LEGPC
Length = 605
Score = 70.1 bits (170), Expect = 1e-10
Identities = 42/112 (37%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Frame = -1
Query: 507 EASKRLEEGVREIHE-LFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSI 331
E + +EEG E ++V G P +I+ F S + + D + +GW LN LQ P+
Sbjct: 440 ELTTLVEEGAGLTSEDIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGF 499
Query: 330 HICITLQHVPV---VDDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMP 187
H+C+T H V F+ DLREAV VK PG G +YGA G MP
Sbjct: 500 HLCLTHVHTVVKGFETQFINDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551
[192][TOP]
>UniRef100_Q4Q758 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Leishmania major RepID=Q4Q758_LEIMA
Length = 537
Score = 70.1 bits (170), Expect = 1e-10
Identities = 42/145 (28%), Positives = 74/145 (51%), Gaps = 11/145 (7%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ KI+ + + + ++ + +IG+P ++ AF S +DIF + D + +GW L
Sbjct: 391 GYVDCCHKIVTTRETMTRELSKLPYIRIIGEPAASVFAFTSNVIDIFRLGDDLKLRGWVL 450
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGP-ITGGLAPI-------- 211
N LQ P + +TL P V FL D++E + + A I G P+
Sbjct: 451 NTLQFPPGLQFSVTLLQTPPAVTARFLSDVKEIGDILFAESEKLIADGKKPVLGESSGTL 510
Query: 210 YGAAGKMPDRGMVNELLVSFMDSQY 136
YG A ++PDR ++ ++L F+++ Y
Sbjct: 511 YGTAQRVPDRTIMQDVLREFLNTYY 535
[193][TOP]
>UniRef100_C6ZD42 Sphingosine 1-phosphate lyase n=1 Tax=Fluoribacter dumoffii
RepID=C6ZD42_9GAMM
Length = 597
Score = 69.7 bits (169), Expect = 2e-10
Identities = 37/128 (28%), Positives = 69/128 (53%), Gaps = 12/128 (9%)
Frame = -1
Query: 534 YLQNTSKIMEASKRLEEGVREIH--------ELFVIGKPDMTIVAFGSKALDIFEVNDIM 379
Y + + I+ +RL++ V E++ ++++ G P +++ F S L+ + + +
Sbjct: 421 YQEISRSIITMRQRLQDKVAELYKPDASGKRDIYIFGNPQWSVLGFRSDTLNPHFIANEL 480
Query: 378 SSKGWHLNALQRPNSIHICITLQHVPV---VDDFLRDLREAVETVKANPG-PITGGLAPI 211
+GW LN+LQ+P+ H+C+T H V D F++DL+E++E VK P G +
Sbjct: 481 DKRGWKLNSLQKPDGFHLCLTHVHTLVDRFEDKFIKDLQESIEAVKQYPADKKPEGNVKV 540
Query: 210 YGAAGKMP 187
YG G +P
Sbjct: 541 YGTIGILP 548
[194][TOP]
>UniRef100_Q4DXI1 Sphingosine phosphate lyase-like protein, putative n=1
Tax=Trypanosoma cruzi RepID=Q4DXI1_TRYCR
Length = 545
Score = 69.7 bits (169), Expect = 2e-10
Identities = 41/147 (27%), Positives = 76/147 (51%), Gaps = 13/147 (8%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY++N KI+ A ++ + ++ + ++G P ++ AF S+ +DIF + D + +GW L
Sbjct: 397 GYVENCRKIVNARIKMTAALSKLPYITILGDPITSVFAFNSECIDIFLLGDRLRERGWAL 456
Query: 357 NALQRPNSIHICITL--QHVPVVDDFLRD-----------LREAVETVKANPGPITGGLA 217
N LQ P+ + +TL + V D F++D ++EA + + GG
Sbjct: 457 NRLQFPSGLQFSVTLLQTNEGVADRFIKDVTSIGEEMYIAVKEAEKEHRVVKKDEAGG-- 514
Query: 216 PIYGAAGKMPDRGMVNELLVSFMDSQY 136
IY + ++ DR +V ++L F+D Y
Sbjct: 515 SIYASQQRVSDRSIVKDILREFLDQYY 541
[195][TOP]
>UniRef100_Q5WUR6 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
pneumophila str. Lens RepID=SGPL_LEGPL
Length = 605
Score = 69.7 bits (169), Expect = 2e-10
Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 4/97 (4%)
Frame = -1
Query: 465 ELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHVPV---V 295
+++V G P +I+ F S + + D + +GW LN LQ P+ H+C+T H V
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVRGFE 514
Query: 294 DDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMP 187
F++DLREAV VK PG G +YGA G MP
Sbjct: 515 TQFIKDLREAVIDVKNYPPGKKASGNVKVYGAVGMMP 551
[196][TOP]
>UniRef100_Q5X3A8 Probable sphingosine-1-phosphate lyase n=1 Tax=Legionella
pneumophila str. Paris RepID=SGPL_LEGPA
Length = 605
Score = 69.3 bits (168), Expect = 2e-10
Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 4/97 (4%)
Frame = -1
Query: 465 ELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHVPV---V 295
+++V G P +I+ F S + + D + +GW LN LQ P+ H+C+T H V
Sbjct: 455 DIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVGSFE 514
Query: 294 DDFLRDLREAVETVK-ANPGPITGGLAPIYGAAGKMP 187
F++DLREAV VK PG G +YGA G MP
Sbjct: 515 TQFIKDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMP 551
[197][TOP]
>UniRef100_O28946 Group II decarboxylase n=1 Tax=Archaeoglobus fulgidus
RepID=O28946_ARCFU
Length = 488
Score = 68.9 bits (167), Expect = 3e-10
Identities = 42/136 (30%), Positives = 78/136 (57%), Gaps = 8/136 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ K + A KRL +G+ E+ L ++G P+ ++AF S+ ++F+V+ +M+ KGW++
Sbjct: 334 GYLKLAKKTLYAKKRLIDGLTELG-LELLGSPEGAVLAFTSERHNLFKVSTLMAEKGWYV 392
Query: 357 NA------LQRPNSIHICITLQHVPVVDDFLRDLREAVETVKAN-PGPITGGLAPI-YGA 202
+ L P S+H + H VVD+FL D+RE + + + P + ++ + +G
Sbjct: 393 QSQPGSKKLGFPRSLHFSVIPGHAEVVDEFLEDMREVLPECECSYPEMSSFDVSKLKFGE 452
Query: 201 AGKMPDRGMVNELLVS 154
G D +++EL+ S
Sbjct: 453 DGLPEDSELISELIHS 468
[198][TOP]
>UniRef100_UPI00016ACD98 sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
MSMB43 RepID=UPI00016ACD98
Length = 473
Score = 68.6 bits (166), Expect = 4e-10
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + + ++ VR I EL V+GKP AF S A D++ VND M GW
Sbjct: 333 GYRARAKAVFDTAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDVYHVNDYMRRHGWRF 391
Query: 357 NALQRPNSIHICIT--LQHVPVVDDFLRDLREAVE 259
N LQ P+++H+C+T V + F +DL EAV+
Sbjct: 392 NGLQHPDALHMCVTGPQTRPGVAERFRQDLGEAVD 426
[199][TOP]
>UniRef100_Q966E7 Putative uncharacterized protein n=1 Tax=Caenorhabditis elegans
RepID=Q966E7_CAEEL
Length = 606
Score = 68.2 bits (165), Expect = 5e-10
Identities = 39/137 (28%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY+ +I+EA+++L ++ + + + G D+ +VAF + ++++ + D+M KGWH+
Sbjct: 410 GYINAAQRIIEATRQLAYRLQGLDGVSLRGSADLCVVAFTTSEVNVYNLVDVMVQKGWHV 469
Query: 357 NALQRPNSIHICITLQ--HVPVVDDFLRDLREAVETVKA-NPGPITGGLAPIYGAAGKMP 187
+ L P + + I+L V+D FL DL A+ +K+ P G A Y K+
Sbjct: 470 DPLLSPAAARVPISLSMCEEGVLDHFLEDLEMAICNLKSMEPAEKLGTTASFYQMLQKVN 529
Query: 186 DRGMVNELLVSFMDSQY 136
D+ +V+EL + + + Y
Sbjct: 530 DKTLVDELSLIRLAAHY 546
[200][TOP]
>UniRef100_Q2T8I7 Sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
E264 RepID=Q2T8I7_BURTA
Length = 473
Score = 67.0 bits (162), Expect = 1e-09
Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY I + + ++ VR I EL V+GKP AF S A DI+ VND M +GW
Sbjct: 333 GYRARARAIFDTAFDMQAAVRAIPELRVLGKPTFCF-AFASDAFDIYHVNDFMRRQGWRF 391
Query: 357 NALQRPNSIHICITLQHVP--VVDDFLRDLREAVE 259
N LQ P+++H+C+T V F +DL AV+
Sbjct: 392 NGLQHPDALHMCVTGPQTQPGVAKRFRQDLGAAVD 426
[201][TOP]
>UniRef100_C5L2Y7 Sphingosine phosphate lyase, putative n=1 Tax=Perkinsus marinus
ATCC 50983 RepID=C5L2Y7_9ALVE
Length = 393
Score = 67.0 bits (162), Expect = 1e-09
Identities = 39/133 (29%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = -1
Query: 510 MEASKRLEEGVREIHELFVIGKPDMTIVAF----GSKALDIFEVNDIMSSKGWHLNALQR 343
+ A+K LE+G+ +I + V+G+P +++VA G D E + W+LN LQ
Sbjct: 260 LSAAKHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKTHWNLNMLQM 319
Query: 342 PNSIHICITLQHVPVVDDFLRDLREAV--ETVKANPGPITG--GLAPIYGAAGKMPDRGM 175
P+ +HIC+T + +D+ L D+ + E K + G +G G A +YG+A +P + +
Sbjct: 320 PSGVHICVTRLNAKKMDELLTDIEAGLKAEKAKLDAGVKSGHSGNAAVYGSAASVP-KEL 378
Query: 174 VNELLVSFMDSQY 136
+ ++ ++D+ Y
Sbjct: 379 ADIVVAKYLDTCY 391
[202][TOP]
>UniRef100_A7NLA0 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus castenholzii
DSM 13941 RepID=A7NLA0_ROSCS
Length = 474
Score = 65.9 bits (159), Expect = 2e-09
Identities = 42/159 (26%), Positives = 83/159 (52%), Gaps = 27/159 (16%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + A++RL GV I L+V+G+P M++ +F S+A+++F++ D + +GW+L
Sbjct: 304 GYRDLVATVQAATERLMAGVDAIDGLYVLGRPAMSMFSFASQAINVFQLADALRRRGWYL 363
Query: 357 ----NALQRPNSIHICIT--------------------LQHVPVVDDFLRDLREAVETVK 250
+ + P ++H+ IT ++H+P +D L +R VE +
Sbjct: 364 QPQFSTPRSPRNLHVSITYGVAHNVDALIADIAACVEEVRHMPPID--LALVRSVVEALT 421
Query: 249 ANPGP--ITGGLAPIYGAAGKMP-DRGMVNELLVSFMDS 142
+P P + G +A + G +P + ++NE+L + D+
Sbjct: 422 QDPSPAVVEGLMAAVGLQPGALPQEMALINEVLDTLPDA 460
[203][TOP]
>UniRef100_A3W9L7 Putative sphingosine-1-phosphate lyase n=1 Tax=Erythrobacter sp.
NAP1 RepID=A3W9L7_9SPHN
Length = 412
Score = 65.9 bits (159), Expect = 2e-09
Identities = 34/97 (35%), Positives = 55/97 (56%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + E +R E+G+ ++ V+GKP + ++AF D F + M KGW
Sbjct: 305 GYREKQGLVCETRERAEKGLAQLR-FEVLGKPMLGLIAFRHPEHDSFALYSEMYRKGWFT 363
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA 247
+ P S+H+ ++ +H V+D +L DLREA ETV+A
Sbjct: 364 SITIDPPSLHLMLSPKHAEVIDQYLDDLREACETVEA 400
[204][TOP]
>UniRef100_C3YZ31 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
RepID=C3YZ31_BRAFL
Length = 112
Score = 65.1 bits (157), Expect = 4e-09
Identities = 31/76 (40%), Positives = 42/76 (55%)
Frame = -1
Query: 471 IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHVPVVD 292
I L ++G+P MT A GSK ++I + D M SKGW + Q PN +H + H V D
Sbjct: 9 IQGLCILGEPHMTAFAIGSKGINILALADEMESKGWRMERTQNPNGLHCTVMPSHTNVRD 68
Query: 291 DFLRDLREAVETVKAN 244
F+ DL A E VK +
Sbjct: 69 KFVEDLTAAAEYVKVS 84
[205][TOP]
>UniRef100_B8FMJ7 Pyridoxal-dependent decarboxylase n=1 Tax=Desulfatibacillum
alkenivorans AK-01 RepID=B8FMJ7_DESAA
Length = 478
Score = 64.7 bits (156), Expect = 6e-09
Identities = 35/114 (30%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GYL+ K +EA K++ G+ +I L ++ +P MT++AF S ++++F + D M+S+GW++
Sbjct: 304 GYLEIARKKLEAVKKITAGIPKIKGLRLLAQPQMTLIAFTSDSVNVFHIIDEMNSRGWYI 363
Query: 357 NAL----QRPNSIHICITLQHVPVVDDFLRDLREAVETVKANP-GPITGGLAPI 211
P IH+ ++ +V D L DL E P G + L P+
Sbjct: 364 QPALSYDNCPAHIHLSVSASNVGWEDKLLEDLEECTAIAAGMPEGELVTSLRPM 417
[206][TOP]
>UniRef100_C5KK71 Sphingosine-1-phosphate lyase, putative n=1 Tax=Perkinsus marinus
ATCC 50983 RepID=C5KK71_9ALVE
Length = 535
Score = 63.9 bits (154), Expect = 9e-09
Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 4/101 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF----GSKALDIFEVNDIMSSK 370
GY ++ I+ A+K LE+G+ +I + V+G+P +++VA G D E +
Sbjct: 414 GYKESCKTIVSAAKHLEKGINDIEGVRVLGRPSVSVVAITCTNGVNDYDFAEWLKNNTKT 473
Query: 369 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA 247
W+LN LQ P+ +HIC+T + +D+ L D+ ++ KA
Sbjct: 474 HWNLNMLQMPSGVHICVTRLNAKKMDELLTDIEAGLKAEKA 514
[207][TOP]
>UniRef100_UPI0001B54B0B Pyridoxal-dependent decarboxylase n=1 Tax=Streptomyces sp. AA4
RepID=UPI0001B54B0B
Length = 471
Score = 63.5 bits (153), Expect = 1e-08
Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 5/107 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF-GSKALDIFEVNDIMSSKGWH 361
GYL+ ++ EA R+ GV EI L V+G P T+VAF GS D+F V D M ++GW+
Sbjct: 292 GYLKLAARAREAVDRIRAGVAEIPGLRVLGDPVSTLVAFTGSDGFDLFTVADEMKARGWY 351
Query: 360 LNAL----QRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPI 232
+ P ++H+ +T + +FL DL +VE +A GP+
Sbjct: 352 VQPQFAHGTSPLNLHLTVTAANHGSEPEFLADLAASVEAARAE-GPV 397
[208][TOP]
>UniRef100_UPI000186B165 hypothetical protein BRAFLDRAFT_112656 n=1 Tax=Branchiostoma
floridae RepID=UPI000186B165
Length = 166
Score = 63.5 bits (153), Expect = 1e-08
Identities = 30/74 (40%), Positives = 41/74 (55%)
Frame = -1
Query: 471 IHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHVPVVD 292
I L ++G+P MT A GS+ ++I + D M SKGW + Q PN +H + H V D
Sbjct: 9 IQGLCILGEPHMTAFAIGSRGINILALADEMESKGWRMERTQNPNGLHCTVMPSHTNVRD 68
Query: 291 DFLRDLREAVETVK 250
F+ DL A E VK
Sbjct: 69 KFVEDLTAAAEYVK 82
[209][TOP]
>UniRef100_A5US78 Pyridoxal-dependent decarboxylase n=1 Tax=Roseiflexus sp. RS-1
RepID=A5US78_ROSS1
Length = 474
Score = 63.5 bits (153), Expect = 1e-08
Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 4/132 (3%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + + A++RL G+ I LFV+G+P M++ +F S +++F + D + +GW+L
Sbjct: 304 GYREIVATVQAATERLIAGINAIDGLFVLGQPAMSMFSFASNNINVFHLADALRRRGWYL 363
Query: 357 ----NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM 190
+ P ++H+ +T V+ L DL VE V+ P + + A +
Sbjct: 364 QPQFSTPLSPRNLHVSVTYGVAHNVEALLADLAACVEEVRQAPPTDPTLIQTLVSAIARD 423
Query: 189 PDRGMVNELLVS 154
P + EL+ +
Sbjct: 424 PSPATIMELMAA 435
[210][TOP]
>UniRef100_C6ZD45 Sphingosine 1-phosphate lyase n=1 Tax=Legionella jamestowniensis
RepID=C6ZD45_9GAMM
Length = 601
Score = 63.5 bits (153), Expect = 1e-08
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 17/131 (12%)
Frame = -1
Query: 528 QNTSKIMEASKRLEEGVR-------------EIHELFVIGKPDMTIVAFGSKALDIFEVN 388
QN KI E+ +L + ++ + +++V G P +++ F S L+ +
Sbjct: 419 QNYQKIAESIVKLRQNLQSKSRWLSYTTTNIQPKDIYVYGNPKWSVLGFRSDTLNPHLIA 478
Query: 387 DIMSSKGWHLNALQRPNSIHICITLQHV---PVVDDFLRDLREAVETVKANPG-PITGGL 220
D + +GW LN LQ P H+C+T H D F+ DL +AV VK P G
Sbjct: 479 DELEKRGWKLNLLQNPAGFHLCLTHVHTLAEGFEDKFISDLGDAVIAVKQYPADKKPSGN 538
Query: 219 APIYGAAGKMP 187
+YGA G MP
Sbjct: 539 VKVYGAVGTMP 549
[211][TOP]
>UniRef100_B1N3J5 Sphingosine-1-phosphate lyase, putative n=1 Tax=Entamoeba
histolytica HM-1:IMSS RepID=B1N3J5_ENTHI
Length = 110
Score = 63.5 bits (153), Expect = 1e-08
Identities = 32/105 (30%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Frame = -1
Query: 441 DMTIVAFGSKALDIFEVNDIMSSK-GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREA 265
D +VAF + L+I++V+D M+ + W N LQ P ++H C+T + + F+ DL +A
Sbjct: 4 DTPVVAFTTTDLNIYKVSDCMNKEFQWEFNTLQFPAAVHFCVTEKTIGCEKQFMEDLNKA 63
Query: 264 VETVKANP-GPITGGLAPIYGAAGKMPD----RGMVNELLVSFMD 145
++ ++ +P P AP+YG +PD MV++++ + D
Sbjct: 64 LDIIRKDPKNPKYNVWAPVYGMTSSLPDIDTLEDMVSQVIAQYCD 108
[212][TOP]
>UniRef100_A9WEY1 Pyridoxal-dependent decarboxylase n=2 Tax=Chloroflexus
RepID=A9WEY1_CHLAA
Length = 474
Score = 62.4 bits (150), Expect = 3e-08
Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 25/159 (15%)
Frame = -1
Query: 543 STGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW 364
+ GY Q + + +A+ RL G+ I +L V+G+P M++VA S +++F++ D M +GW
Sbjct: 302 AVGYRQIVAVVQDATDRLIAGIAAIPDLQVLGQPVMSMVAVASPTINVFQLADAMRRRGW 361
Query: 363 H----LNALQRPNSIHICITLQHVPVVDDFLRDL--------------REAVE------T 256
+ L+A P +IH ++ VD L DL R VE T
Sbjct: 362 YVQPQLSAPHSPRNIHFSVSYGVAGYVDALLADLAACVAEVRHWPPVDRNLVEMAVRSLT 421
Query: 255 VKANPGPITGGLAPIYGAAGKMP-DRGMVNELLVSFMDS 142
V +P + I A G++P D ++NE+L + D+
Sbjct: 422 VDHSPSAVQQLWQAIGLAEGRLPTDMALINEVLDALPDA 460
[213][TOP]
>UniRef100_Q0BY09 Pyridoxal-dependent decarboxylase conserved domain protein n=1
Tax=Hyphomonas neptunium ATCC 15444 RepID=Q0BY09_HYPNA
Length = 412
Score = 61.2 bits (147), Expect = 6e-08
Identities = 31/98 (31%), Positives = 52/98 (53%)
Frame = -1
Query: 540 TGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWH 361
+GY + + + +R+E GV + V+GKP + +VAF D + M +GW
Sbjct: 304 SGYREKQGLVCQTRERIEAGVNALG-FEVLGKPLLGLVAFRHPQADTLALYSAMRQRGWF 362
Query: 360 LNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA 247
+ P S+H+ ++ +H V DD+L DL ++E VKA
Sbjct: 363 TSFTVEPPSLHLMLSPKHAEVADDYLADLAASLEAVKA 400
[214][TOP]
>UniRef100_B4RF80 Putative sphingosine-1-phosphate lyase n=1 Tax=Phenylobacterium
zucineum HLK1 RepID=B4RF80_PHEZH
Length = 408
Score = 61.2 bits (147), Expect = 6e-08
Identities = 30/100 (30%), Positives = 52/100 (52%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + ++ A +R+E GVRE+ VIG+P + ++AF + +D V + +GW
Sbjct: 304 GYRRKHGQVTRARERIEAGVRELG-FSVIGRPQLGLLAFARQDVDCLAVWAKLRERGWFT 362
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPG 238
+ P +H+ ++ H + D +L DL AVE + G
Sbjct: 363 SVTTEPRGLHLMLSPVHAEIADSYLADLAWAVEAARGAAG 402
[215][TOP]
>UniRef100_A0YDC8 Putative sphingosine-1-phosphate lyase n=1 Tax=marine gamma
proteobacterium HTCC2143 RepID=A0YDC8_9GAMM
Length = 410
Score = 60.1 bits (144), Expect = 1e-07
Identities = 30/97 (30%), Positives = 55/97 (56%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY ++ +A K +E GVRE+ ++G P + I+AF +D+F + M +GW
Sbjct: 303 GYKNKHQQVTDARKAIELGVRELG-FTILGTPLLGIIAFQHPDVDVFAIYKQMYDRGWVT 361
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA 247
+ +P ++H+ ++ H V + +L DL E++E VK+
Sbjct: 362 SLTTQPKALHLMLSPFHKTVTNLYLSDLTESIEQVKS 398
[216][TOP]
>UniRef100_Q2NDU7 Putative sphingosine-1-phosphate lyase n=1 Tax=Erythrobacter
litoralis HTCC2594 RepID=Q2NDU7_ERYLH
Length = 412
Score = 59.7 bits (143), Expect = 2e-07
Identities = 31/97 (31%), Positives = 52/97 (53%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY + + +R+E GVRE+ V+G P + ++AF D + + M KGW
Sbjct: 305 GYREKQGLVCATRERVEAGVRELG-FEVLGNPLLGLIAFRHPEHDNYAIYSEMYRKGWFT 363
Query: 357 NALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKA 247
+ P ++H+ ++ +H V+DD+L DL +ETV A
Sbjct: 364 SLTIEPPALHLMLSPKHAEVIDDYLVDLAAGLETVAA 400
[217][TOP]
>UniRef100_A4WKY9 Pyridoxal-dependent decarboxylase n=1 Tax=Pyrobaculum arsenaticum
DSM 13514 RepID=A4WKY9_PYRAR
Length = 500
Score = 58.9 bits (141), Expect = 3e-07
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Frame = -1
Query: 552 FCCSTGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSS 373
F GY + +I+ A ++ G+RE+ ++G+P + I AF S L++F ++D M
Sbjct: 302 FLGEEGYTELARRIIVARNKIVRGLRELG-YNIMGEPTV-IAAFTSSELNLFRLSDEMGK 359
Query: 372 KGWHLNA------LQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPI 211
+GW L + P SIH+ IT H + D L DL+ A E VK P GL I
Sbjct: 360 RGWLLLPQKGIPNMNIPPSIHLTITPIHDKLADIMLGDLKTATEEVKRLPPSEAEGLLEI 419
Query: 210 YGAAGKM 190
+ A M
Sbjct: 420 FTAVFSM 426
[218][TOP]
>UniRef100_C4EIP7 PLP-dependent enzyme, glutamate decarboxylase n=1
Tax=Streptosporangium roseum DSM 43021
RepID=C4EIP7_STRRS
Length = 472
Score = 57.0 bits (136), Expect = 1e-06
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGW-- 364
GYL+ + A++RL EG+ I L V+G P+ +VAFGS +++F ++D +GW
Sbjct: 298 GYLELGRATLAAARRLREGIAGIPGLRVLGDPESALVAFGSDEVNVFVLSDEARKRGWFL 357
Query: 363 --HLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVK-ANPGPITGGLAPI 211
L+ P +IHI +T + V+ L + E+ E + P + GL +
Sbjct: 358 QPQLSYAGIPANIHITVTGVTLRGVEAMLEVIAESAEAARERGPAALPDGLVDL 411
[219][TOP]
>UniRef100_UPI00016A690A sphingosine-1-phosphate lyase n=1 Tax=Burkholderia thailandensis
TXDOH RepID=UPI00016A690A
Length = 104
Score = 56.6 bits (135), Expect = 2e-06
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Frame = -1
Query: 423 FGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVK 250
F S A DI+ VND M +GW N LQ P+++H+C+T V D F +DL EAV+ +
Sbjct: 1 FASDAFDIYHVNDFMRRQGWRFNGLQHPDALHMCVTGPQTQPGVADRFRQDLGEAVDYAR 60
Query: 249 ANPGPITGGLAPIYG 205
+ P + +YG
Sbjct: 61 RHT-PARAQSSGVYG 74
[220][TOP]
>UniRef100_Q23K59 Pyridoxal-dependent decarboxylase conserved domain containing
protein n=1 Tax=Tetrahymena thermophila SB210
RepID=Q23K59_TETTH
Length = 585
Score = 56.2 bits (134), Expect = 2e-06
Identities = 37/139 (26%), Positives = 69/139 (49%), Gaps = 7/139 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREI---HELFVIGKP---DMTIVAFGSKALDIFEVNDIMS 376
GY++ + I A++ + + +RE+ EL VIG P + I+ +I+ + +S
Sbjct: 443 GYVEKSKAISTATQAIVKAIRELPELQELDVIGNPCTCSLAIIYKKETKRNIYHLEGALS 502
Query: 375 SKGWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPI-TGGLAPIYGAA 199
GW + +Q P +I I + + ++DL+ V+ V NP A +YGA+
Sbjct: 503 KLGWKFSGIQLPPAIQISMNHGIANRTKELIKDLKNCVKDVAENPEKYKDSSSASMYGAS 562
Query: 198 GKMPDRGMVNELLVSFMDS 142
K+PD ++ +L + +DS
Sbjct: 563 VKVPDIKTLDRVLDAVVDS 581
[221][TOP]
>UniRef100_UPI000038E421 glutamate decarboxylase n=1 Tax=Ferroplasma acidarmanus fer1
RepID=UPI000038E421
Length = 466
Score = 55.8 bits (133), Expect = 3e-06
Identities = 39/110 (35%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSKGWHL 358
GY SK + A K L +G+ I + GKPD TI AF IF M KGW+
Sbjct: 303 GYTDLASKTLSAYKTLTKGIENIG-YEITGKPDATIFAFQDNNNSIFTTGVNMIEKGWYP 361
Query: 357 N------ALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITG 226
L P++IH+ + HV V D+FL DL E + N G +G
Sbjct: 362 QIQPSNLELGLPSTIHLNVCPVHVEVADEFLSDL----ENIHKNAGKDSG 407
[222][TOP]
>UniRef100_UPI00016A6907 sphingosine-1-phosphate lyase n=2 Tax=Burkholderia thailandensis
RepID=UPI00016A6907
Length = 104
Score = 55.5 bits (132), Expect = 3e-06
Identities = 30/72 (41%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Frame = -1
Query: 423 FGSKALDIFEVNDIMSSKGWHLNALQRPNSIHICITLQHV--PVVDDFLRDLREAVETVK 250
F S A DI+ VND M +GW LN L+ P+++ +C+T V D F RDL AVE +
Sbjct: 1 FTSDAFDIYHVNDFMRQRGWRLNGLRHPDALQMCVTEPQTRPGVADQFRRDLGAAVEHAR 60
Query: 249 --ANPGPITGGL 220
A P T G+
Sbjct: 61 RHARERPKTSGI 72
[223][TOP]
>UniRef100_UPI0001AF1995 pyridoxal-dependent decarboxylase n=1 Tax=Streptomyces ghanaensis
ATCC 14672 RepID=UPI0001AF1995
Length = 493
Score = 55.1 bits (131), Expect = 4e-06
Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 11/129 (8%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAF------GSKALD-IFEVNDIM 379
GY + ++ EA++RL G+RE+ L V+G+PD ++VAF G L + D M
Sbjct: 311 GYTELARRVAEAAERLVPGLREMDGLRVLGEPDGSLVAFTVTGPEGDPDLGLVLHTADEM 370
Query: 378 SSKGWHLNAL----QRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPI 211
++GW+L P ++H+ +T V L DL ++++ +A GP+ A +
Sbjct: 371 RARGWYLQPQLSFDGMPPNLHLTLTPATGDRVGALLADLAQSLKAARA-AGPVVADPALV 429
Query: 210 YGAAGKMPD 184
AAG PD
Sbjct: 430 ALAAGLDPD 438
[224][TOP]
>UniRef100_UPI00019247B9 PREDICTED: similar to predicted protein n=1 Tax=Hydra
magnipapillata RepID=UPI00019247B9
Length = 507
Score = 55.1 bits (131), Expect = 4e-06
Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Frame = -1
Query: 333 IHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKMPDRGMVNELL 160
IHI IT++H V D F+ D++E + NP G IYG + ++PDR ++ E+
Sbjct: 424 IHIAITMRHTKDGVADRFVNDIKEVAARLIKNPSEKAEGQGAIYGLSQQIPDRSIITEIT 483
Query: 159 VSFMDSQY*VS 127
+F+DS Y VS
Sbjct: 484 TAFLDSYYSVS 494
[225][TOP]
>UniRef100_C7MXJ5 PLP-dependent enzyme, glutamate decarboxylase n=1
Tax=Saccharomonospora viridis DSM 43017
RepID=C7MXJ5_SACVD
Length = 483
Score = 54.3 bits (129), Expect = 7e-06
Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 10/113 (8%)
Frame = -1
Query: 537 GYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSK------ALDIFEVNDIMS 376
GYL+ + + A + + G+ I L ++G+PD T++A ++ D+F V D M
Sbjct: 294 GYLRLARETLFAVREIRHGIESIEGLRILGEPDSTLLAVATRGTPEEVGFDLFTVADEMR 353
Query: 375 SKGWHLNAL----QRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPIT 229
+GW++ P ++H+ +T + +F+ DLR++VE A GP++
Sbjct: 354 DRGWYVQPQFAHGHSPVNLHLTVTAANRGSEQEFVVDLRDSVEAACA-AGPVS 405