[UP]
[1][TOP]
>UniRef100_B9DHL6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Arabidopsis
thaliana RepID=B9DHL6_ARATH
Length = 402
Score = 219 bits (557), Expect = 1e-55
Identities = 105/110 (95%), Positives = 107/110 (97%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
VEKSKA PSITYMAVNKSENWVSN GESDVNAVTWGVFPAK+VIQPTIVDPASFKVWKDE
Sbjct: 293 VEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 352
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIWSRSWANLYPEDDPSRKLLEEVK+SYYLVSLVD NYINGDIFSVFA
Sbjct: 353 AFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVFA 402
[2][TOP]
>UniRef100_Q9SE60 Methylenetetrahydrofolate reductase 1 n=1 Tax=Arabidopsis thaliana
RepID=MTHR1_ARATH
Length = 592
Score = 219 bits (557), Expect = 1e-55
Identities = 105/110 (95%), Positives = 107/110 (97%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
VEKSKA PSITYMAVNKSENWVSN GESDVNAVTWGVFPAK+VIQPTIVDPASFKVWKDE
Sbjct: 483 VEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIWSRSWANLYPEDDPSRKLLEEVK+SYYLVSLVD NYINGDIFSVFA
Sbjct: 543 AFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVFA 592
[3][TOP]
>UniRef100_O80585 Methylenetetrahydrofolate reductase 2 n=1 Tax=Arabidopsis thaliana
RepID=MTHR2_ARATH
Length = 594
Score = 195 bits (496), Expect = 1e-48
Identities = 91/110 (82%), Positives = 100/110 (90%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
VEK KA+PSITYMAVNK E WVSN ++DVNAVTWGVFPAK++IQPTIVDPASF VWKDE
Sbjct: 483 VEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFE WSRSWANLYPE DPSR LLEEVK+SYYLVSLV+ +YINGDIF+VFA
Sbjct: 543 AFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFA 592
[4][TOP]
>UniRef100_B9STA4 Methylenetetrahydrofolate reductase n=1 Tax=Ricinus communis
RepID=B9STA4_RICCO
Length = 609
Score = 182 bits (462), Expect = 1e-44
Identities = 82/110 (74%), Positives = 98/110 (89%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK KA+P +TYMAVN+ +SN+G++DVNAVTWGVFP KQ+IQPT+VDPASF VWKDE
Sbjct: 498 LEKCKALPQLTYMAVNRGGTLLSNVGQNDVNAVTWGVFPGKQIIQPTVVDPASFSVWKDE 557
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIW+R WA+LYPE DPSRKLLEEV+SSY+LVSLVD +YI GDIF+VFA
Sbjct: 558 AFEIWTRGWASLYPESDPSRKLLEEVQSSYFLVSLVDNDYIQGDIFAVFA 607
[5][TOP]
>UniRef100_B9HG95 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9HG95_POPTR
Length = 608
Score = 179 bits (455), Expect = 7e-44
Identities = 80/110 (72%), Positives = 97/110 (88%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
VE+ KA P +TYMAVN+ +W+SN+ +DVNAVTWGVFPAK++IQPT+VDP SF VWKDE
Sbjct: 497 VERCKAFPLVTYMAVNRGGSWISNVALTDVNAVTWGVFPAKEIIQPTVVDPTSFSVWKDE 556
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIWSR WA+LYPE DPSR LLEEV++SY+LVSLVD +YI+GDIF+VFA
Sbjct: 557 AFEIWSRGWASLYPEGDPSRTLLEEVQNSYFLVSLVDNDYIHGDIFAVFA 606
[6][TOP]
>UniRef100_A5ATB7 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A5ATB7_VITVI
Length = 594
Score = 179 bits (455), Expect = 7e-44
Identities = 79/109 (72%), Positives = 97/109 (88%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K K PS+TYMAVNK W+SN+G +VNAVTWGVFPA+++IQPT+VDP+SF VWKDE
Sbjct: 483 VDKCKGHPSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWSR WA LYPEDDPSRKLLEEV++S++LVSLVD +YINGD+F++F
Sbjct: 543 AFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDNDYINGDLFAIF 591
[7][TOP]
>UniRef100_B9N8L0 Methylenetetrahydrofolate reductase n=1 Tax=Populus trichocarpa
RepID=B9N8L0_POPTR
Length = 606
Score = 177 bits (450), Expect = 3e-43
Identities = 79/110 (71%), Positives = 96/110 (87%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K K+ P +TY+AVNK +W+SN+ +DVNAVTWGVFP K++IQPT+VDP SF VWKDE
Sbjct: 494 VDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDE 553
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIWSR WA+LYPE DPSR LLEEV+SSY+LVSLVD +YI+GDIF+VFA
Sbjct: 554 AFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVSLVDNDYIHGDIFAVFA 603
[8][TOP]
>UniRef100_A9P8D1 Putative uncharacterized protein n=1 Tax=Populus trichocarpa
RepID=A9P8D1_POPTR
Length = 224
Score = 177 bits (450), Expect = 3e-43
Identities = 79/110 (71%), Positives = 96/110 (87%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K K+ P +TY+AVNK +W+SN+ +DVNAVTWGVFP K++IQPT+VDP SF VWKDE
Sbjct: 113 VDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPGKEIIQPTVVDPTSFSVWKDE 172
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AFEIWSR WA+LYPE DPSR LLEEV+SSY+LVSLVD +YI+GDIF+VFA
Sbjct: 173 AFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVSLVDNDYIHGDIFAVFA 222
[9][TOP]
>UniRef100_UPI00019838C7 PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera
RepID=UPI00019838C7
Length = 594
Score = 176 bits (447), Expect = 6e-43
Identities = 78/109 (71%), Positives = 96/109 (88%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K K S+TYMAVNK W+SN+G +VNAVTWGVFPA+++IQPT+VDP+SF VWKDE
Sbjct: 483 VDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWSR WA LYPEDDPSRKLLEEV++S++LVSLVD +YINGD+F++F
Sbjct: 543 AFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDNDYINGDLFAIF 591
[10][TOP]
>UniRef100_A7PSQ4 Methylenetetrahydrofolate reductase n=1 Tax=Vitis vinifera
RepID=A7PSQ4_VITVI
Length = 587
Score = 176 bits (447), Expect = 6e-43
Identities = 78/109 (71%), Positives = 96/109 (88%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K K S+TYMAVNK W+SN+G +VNAVTWGVFPA+++IQPT+VDP+SF VWKDE
Sbjct: 476 VDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWKDE 535
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWSR WA LYPEDDPSRKLLEEV++S++LVSLVD +YINGD+F++F
Sbjct: 536 AFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDNDYINGDLFAIF 584
[11][TOP]
>UniRef100_A9U4S7 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9U4S7_PHYPA
Length = 592
Score = 168 bits (426), Expect = 2e-40
Identities = 75/110 (68%), Positives = 92/110 (83%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK+K PS+TY+AVN SN+G + VNAVTWGVFPAK+VIQPT+VDP SF VWKDE
Sbjct: 483 IEKAKTSPSLTYIAVNAKGETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AF+ W + WA+LYPEDD SRK+L E+KSSY+LVS+VD +YINGD+FSVFA
Sbjct: 543 AFQAWDQEWASLYPEDDASRKILSEIKSSYFLVSMVDNDYINGDLFSVFA 592
[12][TOP]
>UniRef100_B8LKP0 Methylenetetrahydrofolate reductase n=1 Tax=Picea sitchensis
RepID=B8LKP0_PICSI
Length = 594
Score = 168 bits (425), Expect = 2e-40
Identities = 75/109 (68%), Positives = 94/109 (86%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
VEK+K +P +TY+AVNK +NIG +DVNAVTWGVFPAK+VIQPT+VDP SF VWKDE
Sbjct: 483 VEKAKNLPFVTYIAVNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AF+ W + WA+LYP+ DPSRK+LEEV++SYYLVS+VD +YI+GD+FSVF
Sbjct: 543 AFQAWEQEWASLYPDGDPSRKILEEVQNSYYLVSVVDNDYIHGDLFSVF 591
[13][TOP]
>UniRef100_A6XMY8 Methylenetetrahydrofolate reductase n=1 Tax=Triticum monococcum
RepID=A6XMY8_TRIMO
Length = 582
Score = 162 bits (410), Expect = 1e-38
Identities = 74/109 (67%), Positives = 91/109 (83%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EKSKA PS+TY+AVNK +SNI + VNAVTWGVFP K++IQPT+VD ASF VWKDE
Sbjct: 471 IEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDE 530
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWSR WA L+PE D SR+LLE+++ SYYLVSLVD +YI+GD+F+ F
Sbjct: 531 AFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAF 579
[14][TOP]
>UniRef100_C5WVY7 Methylenetetrahydrofolate reductase n=1 Tax=Sorghum bicolor
RepID=C5WVY7_SORBI
Length = 593
Score = 160 bits (405), Expect = 4e-38
Identities = 73/109 (66%), Positives = 89/109 (81%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK KA PS+TY+AVNK SNI + VNAVTWGVFP K++IQPT+VDPASF VWKDE
Sbjct: 483 IEKIKAFPSLTYIAVNKDGESFSNIAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIW+R WA L+PE D SR+LLE+V+ SYYLVSLVD +Y+ GD+F+ F
Sbjct: 543 AFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVSLVDNDYVQGDLFAAF 591
[15][TOP]
>UniRef100_A6N158 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Oryza sativa
Indica Group RepID=A6N158_ORYSI
Length = 237
Score = 157 bits (398), Expect = 3e-37
Identities = 71/109 (65%), Positives = 90/109 (82%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EKSKA PS+TY+AVNK SNI + VNAVTWGVFP K+++QPT+VD ASF VWKDE
Sbjct: 126 IEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDE 185
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWS+ WA L+PE D SR++L++V+ SY+LVSLVD +YINGD+F+ F
Sbjct: 186 AFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAF 234
[16][TOP]
>UniRef100_Q75HE6 Probable methylenetetrahydrofolate reductase n=3 Tax=Oryza sativa
RepID=MTHR_ORYSJ
Length = 594
Score = 157 bits (398), Expect = 3e-37
Identities = 71/109 (65%), Positives = 90/109 (82%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EKSKA PS+TY+AVNK SNI + VNAVTWGVFP K+++QPT+VD ASF VWKDE
Sbjct: 483 IEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIWS+ WA L+PE D SR++L++V+ SY+LVSLVD +YINGD+F+ F
Sbjct: 543 AFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAF 591
[17][TOP]
>UniRef100_A9RW65 Methylenetetrahydrofolate reductase n=1 Tax=Physcomitrella patens
subsp. patens RepID=A9RW65_PHYPA
Length = 594
Score = 157 bits (397), Expect = 4e-37
Identities = 71/110 (64%), Positives = 89/110 (80%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK+K+ PS+T++AVN SNIG + VNAVTWGVFPAK+VIQPT+VDP SF VWKDE
Sbjct: 483 IEKAKSNPSLTFIAVNAKGETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVFA 164
AF+ W WA LY E+D SRK+L E+K SY+LVS+VD +YINGD+F+VFA
Sbjct: 543 AFQTWDHEWAALYSEEDSSRKILSEIKDSYFLVSMVDNDYINGDLFAVFA 592
[18][TOP]
>UniRef100_Q9SE94 Methylenetetrahydrofolate reductase 1 n=1 Tax=Zea mays
RepID=MTHR1_MAIZE
Length = 593
Score = 154 bits (388), Expect = 4e-36
Identities = 69/109 (63%), Positives = 87/109 (79%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK KA PS+TY+AVNK SNI + VNAVTWGVFP K++IQPT+VD ASF VWKDE
Sbjct: 483 IEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AFEIW+R W ++PE D SR+LLE+V+ +YYLVSLVD +Y+ GD+F+ F
Sbjct: 543 AFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAF 591
[19][TOP]
>UniRef100_Q10BJ6 Methylenetetrahydrofolate reductase n=1 Tax=Oryza sativa Japonica
Group RepID=Q10BJ6_ORYSJ
Length = 573
Score = 124 bits (312), Expect = 3e-27
Identities = 56/86 (65%), Positives = 70/86 (81%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EKSKA PS+TY+AVNK SNI + VNAVTWGVFP K+++QPT+VD ASF VWKDE
Sbjct: 483 IEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDE 542
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEV 236
AFEIWS+ WA L+PE D SR++L++V
Sbjct: 543 AFEIWSKGWACLFPEGDSSREILDKV 568
[20][TOP]
>UniRef100_A8IAY6 Methylenetetrahydrofolate reductase n=1 Tax=Chlamydomonas
reinhardtii RepID=A8IAY6_CHLRE
Length = 594
Score = 119 bits (297), Expect = 1e-25
Identities = 56/106 (52%), Positives = 71/106 (66%)
Frame = -1
Query: 487 KSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAF 308
K A PSITY+A + + N+ VNAVTWGVFP K+VIQPT+V SF VWKDEAF
Sbjct: 486 KLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCAPSFAVWKDEAF 545
Query: 307 EIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSV 170
E+W+ W LY E +R LL +K S+ LVS+VD +Y+ GD+F V
Sbjct: 546 ELWTSEWGALYEEGSAARDLLAGIKDSWVLVSVVDNDYVAGDLFGV 591
[21][TOP]
>UniRef100_Q54X84 Methylenetetrahydrofolate reductase n=1 Tax=Dictyostelium
discoideum RepID=Q54X84_DICDI
Length = 627
Score = 116 bits (291), Expect = 7e-25
Identities = 53/109 (48%), Positives = 72/109 (66%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+E K P ITY AVN+ + S NAVTWG+FP K++IQPT+VD SF VWKDE
Sbjct: 491 IEYFKKCPMITYHAVNRKGD--SKTNTKGTNAVTWGIFPGKEIIQPTVVDHNSFMVWKDE 548
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
AF +W W++ Y SR LL+ + ++YYL+++VD N+ING+IF F
Sbjct: 549 AFALWETQWSSTYSPSSTSRTLLDSMINNYYLINIVDNNFINGNIFQSF 597
[22][TOP]
>UniRef100_A7S360 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S360_NEMVE
Length = 612
Score = 108 bits (271), Expect = 1e-22
Identities = 45/105 (42%), Positives = 71/105 (67%), Gaps = 1/105 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENW-VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKD 317
+++ K P + Y VN + ++N AVTWGVFP ++++QPT+VDP SFK+WKD
Sbjct: 471 LQELKNYPQVNYHVVNNHDTVDITNCDSQTPVAVTWGVFPGREIVQPTVVDPISFKIWKD 530
Query: 316 EAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
EAF +W + W+ LY ED SR ++ ++ ++Y LV+LVD ++I G+
Sbjct: 531 EAFSLWEQQWSRLYTEDSKSRAIINKIMNTYCLVNLVDNDFIKGN 575
[23][TOP]
>UniRef100_Q7ZWU2 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus laevis
RepID=Q7ZWU2_XENLA
Length = 643
Score = 108 bits (270), Expect = 2e-22
Identities = 44/93 (47%), Positives = 63/93 (67%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P + Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W
Sbjct: 528 PRVNYHIVNVHGQNITNAADLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIE 587
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 588 QWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 620
[24][TOP]
>UniRef100_B0V153 Methylenetetrahydrofolate reductase n=1 Tax=Danio rerio
RepID=B0V153_DANRE
Length = 656
Score = 107 bits (266), Expect = 5e-22
Identities = 42/93 (45%), Positives = 63/93 (67%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P + Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W
Sbjct: 534 PRVNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIE 593
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA LY ++ PSR +++ + +Y+LV+LVD ++
Sbjct: 594 QWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDF 626
[25][TOP]
>UniRef100_A4IIX8 Methylenetetrahydrofolate reductase n=1 Tax=Xenopus (Silurana)
tropicalis RepID=A4IIX8_XENTR
Length = 643
Score = 107 bits (266), Expect = 5e-22
Identities = 43/93 (46%), Positives = 63/93 (67%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P + Y VN ++N + +AVTWG+FP +++IQPT+VDP SF WKDEAF +W
Sbjct: 528 PRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIE 587
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 588 QWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 620
[26][TOP]
>UniRef100_UPI000194DA90 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Taeniopygia guttata RepID=UPI000194DA90
Length = 651
Score = 105 bits (262), Expect = 2e-21
Identities = 43/91 (47%), Positives = 62/91 (68%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 538 VNYHIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQW 597
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
A LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 598 AKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 628
[27][TOP]
>UniRef100_UPI0000E814FF PREDICTED: similar to Mthfr-prov protein n=1 Tax=Gallus gallus
RepID=UPI0000E814FF
Length = 508
Score = 105 bits (262), Expect = 2e-21
Identities = 43/91 (47%), Positives = 62/91 (68%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 395 VNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQW 454
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
A LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 455 AKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 485
[28][TOP]
>UniRef100_UPI0000ECA34F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Gallus
gallus RepID=UPI0000ECA34F
Length = 640
Score = 105 bits (262), Expect = 2e-21
Identities = 43/91 (47%), Positives = 62/91 (68%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 527 VNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQW 586
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
A LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 587 AKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 617
[29][TOP]
>UniRef100_B3S098 Methylenetetrahydrofolate reductase n=1 Tax=Trichoplax adhaerens
RepID=B3S098_TRIAD
Length = 633
Score = 105 bits (262), Expect = 2e-21
Identities = 47/97 (48%), Positives = 67/97 (69%), Gaps = 1/97 (1%)
Frame = -1
Query: 472 PSITYMAVNKSENW-VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
P I Y A++ SE+ VSN AVTWGVFP ++++QPT+VDP SF WKDEAF +W+
Sbjct: 517 PMINYHALDLSESINVSNSDHHQPIAVTWGVFPGREILQPTVVDPTSFSYWKDEAFALWT 576
Query: 295 RSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING 185
WANLYPE+ SR+++ ++ LV++VD ++I G
Sbjct: 577 NQWANLYPEESKSRQVITAAVRNFVLVNMVDNDFIQG 613
[30][TOP]
>UniRef100_A7S5W8 Methylenetetrahydrofolate reductase n=1 Tax=Nematostella vectensis
RepID=A7S5W8_NEMVE
Length = 619
Score = 105 bits (262), Expect = 2e-21
Identities = 46/96 (47%), Positives = 64/96 (66%), Gaps = 1/96 (1%)
Frame = -1
Query: 466 ITYMAVNKS-ENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
I + VN S E+ +N NAVTWGVFP +++QPT+VDP +F WKDEAF +W +
Sbjct: 509 INFHLVNSSGESDFTNANMYSPNAVTWGVFPGSEILQPTVVDPIAFHYWKDEAFGLWKQQ 568
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
W LYPE SR +++ + SYYLV+LVD +Y+ G+
Sbjct: 569 WGRLYPEGSRSRDIIDSIYDSYYLVNLVDNDYVGGN 604
[31][TOP]
>UniRef100_UPI0000E1E642 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
3 n=2 Tax=Pan troglodytes RepID=UPI0000E1E642
Length = 679
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 559 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERW 618
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 619 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 649
[32][TOP]
>UniRef100_UPI0000E1E641 PREDICTED: 5,10-methylenetetrahydrofolate reductase (NADPH) isoform
4 n=1 Tax=Pan troglodytes RepID=UPI0000E1E641
Length = 697
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 577 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERW 636
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 637 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 667
[33][TOP]
>UniRef100_UPI0000D99720 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 2 n=2 Tax=Macaca mulatta RepID=UPI0000D99720
Length = 679
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 559 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 618
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 619 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 649
[34][TOP]
>UniRef100_UPI0000D9971F PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
isoform 3 n=1 Tax=Macaca mulatta RepID=UPI0000D9971F
Length = 697
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 577 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 636
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 637 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 667
[35][TOP]
>UniRef100_P42898 Methylenetetrahydrofolate reductase n=2 Tax=Homo sapiens
RepID=MTHR_HUMAN
Length = 656
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 536 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERW 595
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 596 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626
[36][TOP]
>UniRef100_Q60HE5 Methylenetetrahydrofolate reductase n=1 Tax=Macaca fascicularis
RepID=MTHR_MACFA
Length = 656
Score = 103 bits (258), Expect = 5e-21
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 536 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 595
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD ++
Sbjct: 596 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626
[37][TOP]
>UniRef100_UPI0000F2D0FD PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Monodelphis domestica RepID=UPI0000F2D0FD
Length = 642
Score = 103 bits (257), Expect = 6e-21
Identities = 42/91 (46%), Positives = 60/91 (65%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 530 VNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW 589
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD +
Sbjct: 590 GKLYEEESPSRMIIQYIHDNYHLVNLVDNEF 620
[38][TOP]
>UniRef100_C5L500 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5L500_9ALVE
Length = 631
Score = 103 bits (257), Expect = 6e-21
Identities = 52/102 (50%), Positives = 73/102 (71%), Gaps = 3/102 (2%)
Frame = -1
Query: 469 SITYMAVNKSENWV-SNIG-ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
SI+YMAV + V SNI + VNAVTWGVFP ++IQPT+VD SF WKDEAF +W+
Sbjct: 467 SISYMAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN 526
Query: 295 RSWANLYPEDD-PSRKLLEEVKSSYYLVSLVDTNYINGDIFS 173
W ++YPEDD SR++L ++ Y+L ++VD +++ GD+FS
Sbjct: 527 -EWMDVYPEDDHQSRQVLNFIRQHYFLCTVVDNDFVAGDLFS 567
[39][TOP]
>UniRef100_C5K575 Methylenetetrahydrofolate reductase n=1 Tax=Perkinsus marinus ATCC
50983 RepID=C5K575_9ALVE
Length = 583
Score = 103 bits (257), Expect = 6e-21
Identities = 52/102 (50%), Positives = 73/102 (71%), Gaps = 3/102 (2%)
Frame = -1
Query: 469 SITYMAVNKSENWV-SNIG-ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
SI+YMAV + V SNI + VNAVTWGVFP ++IQPT+VD SF WKDEAF +W+
Sbjct: 446 SISYMAVTADGSKVRSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWN 505
Query: 295 RSWANLYPEDD-PSRKLLEEVKSSYYLVSLVDTNYINGDIFS 173
W ++YPEDD SR++L ++ Y+L ++VD +++ GD+FS
Sbjct: 506 -EWMDVYPEDDHQSRQVLNFIRQHYFLCTVVDNDFVAGDLFS 546
[40][TOP]
>UniRef100_Q5K8Q9 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5K8Q9_CRYNE
Length = 617
Score = 103 bits (257), Expect = 6e-21
Identities = 51/103 (49%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P ITY AVNK + +N NAVTWGVFP K+++QPTIV+ SF WKDEAFE+
Sbjct: 485 PRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFEL-GL 543
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
WA+LYP + PSRKL+ + ++ YLV++V ++ +G IF F
Sbjct: 544 QWAHLYPAESPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPF 586
[41][TOP]
>UniRef100_UPI00006A3477 PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase
(NADPH) n=1 Tax=Ciona intestinalis RepID=UPI00006A3477
Length = 644
Score = 103 bits (256), Expect = 8e-21
Identities = 45/94 (47%), Positives = 64/94 (68%), Gaps = 1/94 (1%)
Frame = -1
Query: 472 PSITYMAVNKSENWV-SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
P + Y +NK +N S+ NAVTWG+F K++IQPT+VDP SF VWKDEAF +W
Sbjct: 507 PRVNYHMINKCGTTDHTNADRSNPNAVTWGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWH 566
Query: 295 RSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA+LY + SR+++ ++ +YYLV+LVD +Y
Sbjct: 567 ERWASLYEKGSKSREIINDIADNYYLVNLVDNDY 600
[42][TOP]
>UniRef100_C3XPI2 Methylenetetrahydrofolate reductase n=2 Tax=Branchiostoma floridae
RepID=C3XPI2_BRAFL
Length = 686
Score = 103 bits (256), Expect = 8e-21
Identities = 44/99 (44%), Positives = 67/99 (67%), Gaps = 1/99 (1%)
Frame = -1
Query: 472 PSITYMAVN-KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
P++ Y + + ++ +N + AVTWGVFP K++IQPT+VDP SFK WKDEAF +W+
Sbjct: 522 PNVNYHIIKFEGDDDYTNCDQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWT 581
Query: 295 RSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDI 179
W LY ED SR+L++ + ++YLV+LVD ++ +I
Sbjct: 582 EYWGQLYAEDSKSRELIQHIHDTWYLVNLVDNDFPRDNI 620
[43][TOP]
>UniRef100_UPI0001555C53 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Ornithorhynchus anatinus RepID=UPI0001555C53
Length = 646
Score = 102 bits (254), Expect = 1e-20
Identities = 41/91 (45%), Positives = 60/91 (65%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+ Y VN ++N + NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W
Sbjct: 533 VNYHIVNVKGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQW 592
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
LY E+ PSR +++ + +Y+LV+LVD +
Sbjct: 593 GKLYEEESPSRMIIQYIHDNYHLVNLVDNEF 623
[44][TOP]
>UniRef100_UPI000155DDC5 PREDICTED: similar to methylenetetrahydrofolate reductase n=1
Tax=Equus caballus RepID=UPI000155DDC5
Length = 655
Score = 102 bits (253), Expect = 2e-20
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 543 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 601
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD ++
Sbjct: 602 SPSRMIIQYIHDNYFLVNLVDNDF 625
[45][TOP]
>UniRef100_UPI0000DA28B6 PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Rattus norvegicus RepID=UPI0000DA28B6
Length = 660
Score = 102 bits (253), Expect = 2e-20
Identities = 41/85 (48%), Positives = 60/85 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP ++++QPT+VDP SF WKDEAF +W W LY E+
Sbjct: 549 KGEN-ITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 607
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNYI 191
PSR +++ + +Y+LV+LVD ++
Sbjct: 608 SPSRMIIQYIHDNYFLVNLVDNEFL 632
[46][TOP]
>UniRef100_UPI00005A03BF PREDICTED: similar to Methylenetetrahydrofolate reductase n=1
Tax=Canis lupus familiaris RepID=UPI00005A03BF
Length = 780
Score = 102 bits (253), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 669 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE 727
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 728 SPSRMIIQYIHDNYFLVNLVDNEF 751
[47][TOP]
>UniRef100_UPI0000DBFF71 Methylenetetrahydrofolate reductase n=1 Tax=Rattus norvegicus
RepID=UPI0000DBFF71
Length = 695
Score = 102 bits (253), Expect = 2e-20
Identities = 41/85 (48%), Positives = 60/85 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP ++++QPT+VDP SF WKDEAF +W W LY E+
Sbjct: 584 KGEN-ITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 642
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNYI 191
PSR +++ + +Y+LV+LVD ++
Sbjct: 643 SPSRMIIQYIHDNYFLVNLVDNEFL 667
[48][TOP]
>UniRef100_UPI0000EB3A6F Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Canis
lupus familiaris RepID=UPI0000EB3A6F
Length = 696
Score = 102 bits (253), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 585 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE 643
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 644 SPSRMIIQYIHDNYFLVNLVDNEF 667
[49][TOP]
>UniRef100_UPI0000614ECA Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=2 Tax=Bos
taurus RepID=UPI0000614ECA
Length = 655
Score = 102 bits (253), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 543 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE 601
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 602 SPSRMIIQYIHDNYFLVNLVDNEF 625
[50][TOP]
>UniRef100_Q5I598 Methylenetetrahydrofolate reductase n=1 Tax=Bos taurus
RepID=MTHR_BOVIN
Length = 655
Score = 102 bits (253), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 543 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE 601
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 602 SPSRMIIQYIHDNYFLVNLVDNEF 625
[51][TOP]
>UniRef100_Q497H7 Mthfr protein (Fragment) n=2 Tax=Mus musculus RepID=Q497H7_MOUSE
Length = 166
Score = 101 bits (252), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 55 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 113
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 114 SPSRMIIQYIHDNYFLVNLVDNEF 137
[52][TOP]
>UniRef100_B2KFL4 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=B2KFL4_MOUSE
Length = 695
Score = 101 bits (252), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 584 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 642
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 643 SPSRMIIQYIHDNYFLVNLVDNEF 666
[53][TOP]
>UniRef100_A2A7F7 Methylenetetrahydrofolate reductase n=2 Tax=Mus musculus
RepID=A2A7F7_MOUSE
Length = 695
Score = 101 bits (252), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 584 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 642
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 643 SPSRMIIQYIHDNYFLVNLVDNEF 666
[54][TOP]
>UniRef100_Q9WU20 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=MTHR_MOUSE
Length = 654
Score = 101 bits (252), Expect = 2e-20
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF +W W LY E+
Sbjct: 543 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEE 601
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 602 SPSRMIIQYIHDNYFLVNLVDNEF 625
[55][TOP]
>UniRef100_UPI00017B529C UPI00017B529C related cluster n=1 Tax=Tetraodon nigroviridis
RepID=UPI00017B529C
Length = 660
Score = 101 bits (251), Expect = 3e-20
Identities = 40/93 (43%), Positives = 62/93 (66%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P + Y VN ++N + NAVTWG+F ++++QPT+VDP SF WKDEAF +W
Sbjct: 538 PRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIE 597
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA LY ++ PSR +++ + +Y+LV+LVD ++
Sbjct: 598 QWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDF 630
[56][TOP]
>UniRef100_Q4P5K1 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P5K1_USTMA
Length = 650
Score = 101 bits (251), Expect = 3e-20
Identities = 52/110 (47%), Positives = 71/110 (64%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+ + +A P ITY AVN + +N NAVTWGVFP ++IQPTIV+ SF WKDE
Sbjct: 490 IARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVESISFLAWKDE 549
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A+EI R+WA +Y PSRK LE++ +SY+LV++V ++ N IF F
Sbjct: 550 AYEI-GRNWAKVYEPTSPSRKFLEDMFNSYFLVNVVHNDFKANDSIFEPF 598
[57][TOP]
>UniRef100_B2B2M5 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B2M5_PODAN
Length = 610
Score = 100 bits (250), Expect = 4e-20
Identities = 48/97 (49%), Positives = 65/97 (67%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV KS +N NAVTWGVFP K+++QPTIV+ SF WKDEAF++ S
Sbjct: 480 PDLTYHAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGS- 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
WA Y D PSR LLE++ S+YLV++V+ ++ G+
Sbjct: 539 DWARCYEADTPSRLLLEDIMKSWYLVNIVNNDFHQGE 575
[58][TOP]
>UniRef100_Q7S830 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S830_NEUCR
Length = 613
Score = 100 bits (249), Expect = 5e-20
Identities = 46/93 (49%), Positives = 62/93 (66%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P ITY AV KS N +N NAVTWGVFP K+++QPTIV+ SF WKDEAF++
Sbjct: 480 PDITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQL-GL 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA Y D PSR L+EE+ +YL+++V+ ++
Sbjct: 539 EWARCYDADTPSRLLIEEIMDKWYLINIVNNDF 571
[59][TOP]
>UniRef100_Q3UDB2 Methylenetetrahydrofolate reductase n=1 Tax=Mus musculus
RepID=Q3UDB2_MOUSE
Length = 695
Score = 99.8 bits (247), Expect = 9e-20
Identities = 42/84 (50%), Positives = 58/84 (69%)
Frame = -1
Query: 445 KSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPED 266
K EN ++N E NAVTWG+FP +++IQPT+VDP SF WKDEAF W W LY E+
Sbjct: 584 KGEN-ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEE 642
Query: 265 DPSRKLLEEVKSSYYLVSLVDTNY 194
PSR +++ + +Y+LV+LVD +
Sbjct: 643 SPSRMIIQYIHDNYFLVNLVDNEF 666
[60][TOP]
>UniRef100_Q2H0T7 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2H0T7_CHAGB
Length = 616
Score = 99.0 bits (245), Expect = 1e-19
Identities = 48/102 (47%), Positives = 68/102 (66%), Gaps = 1/102 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV KS N +N NAVTWGVFP K+++QPTIV+ SF WKDEAF++
Sbjct: 480 PDLTYHAVTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQL-GM 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD-IFSV 170
WA Y PSR +L+E+ +++YLV++V+ ++ G+ IF V
Sbjct: 539 EWARCYETGTPSRSILDEIMNTWYLVNIVNNDFHRGETIFEV 580
[61][TOP]
>UniRef100_Q6FNS2 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FNS2_CANGA
Length = 645
Score = 98.2 bits (243), Expect = 3e-19
Identities = 47/94 (50%), Positives = 61/94 (64%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y A + ++ +N+ N VTWGVFP QVIQ TI++ SFK W+DEAF IWS WA
Sbjct: 545 SYYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS-EWA 603
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + PS LL EV S YYLVS+V ++I D
Sbjct: 604 KLFPRNTPSNTLLREVHSDYYLVSIVHHDFIETD 637
[62][TOP]
>UniRef100_UPI00019265CF PREDICTED: similar to 5,10-methylenetetrahydrofolate reductase n=1
Tax=Hydra magnipapillata RepID=UPI00019265CF
Length = 623
Score = 97.1 bits (240), Expect = 6e-19
Identities = 39/73 (53%), Positives = 54/73 (73%)
Frame = -1
Query: 400 AVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYY 221
AVTWGVFP K++IQPT+VDP SF WKDEAF +W W +LY + S K+++ + + +Y
Sbjct: 536 AVTWGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFY 595
Query: 220 LVSLVDTNYINGD 182
LV+LVD +YI G+
Sbjct: 596 LVNLVDNDYIKGN 608
[63][TOP]
>UniRef100_C4R2Q6 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2Q6_PICPG
Length = 603
Score = 97.1 bits (240), Expect = 6e-19
Identities = 46/114 (40%), Positives = 74/114 (64%), Gaps = 13/114 (11%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
++T+ AVN ++N E D+NAVTWG+FP K+V+QPTIV+ SF WKDEAF ++ ++
Sbjct: 487 TLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAFRVF-KA 545
Query: 289 WANLYPE----------DDPSRKLLEEVKSSYYLVSLVDTNYI---NGDIFSVF 167
W++L+ + D +R +L+++ Y+LV++VD NY+ N IF +F
Sbjct: 546 WSSLFKDQDQDEFEVLRDSKTRAVLDKLHDEYFLVNIVDNNYVQNPNVKIFDLF 599
[64][TOP]
>UniRef100_Q5KN82 Methylenetetrahydrofolate reductase n=1 Tax=Filobasidiella
neoformans RepID=Q5KN82_CRYNE
Length = 633
Score = 96.7 bits (239), Expect = 7e-19
Identities = 43/91 (47%), Positives = 64/91 (70%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
IT A N+ ++ +N + VNAVTWGVFP +++ Q TI++ SF WK+EAF+IW+ W
Sbjct: 529 ITMYAANRKGDFKTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWA-EW 587
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
+ LYP + PSRKLLE + + ++LVSL+ +Y
Sbjct: 588 SLLYPRNTPSRKLLEGIANEWWLVSLIHHDY 618
[65][TOP]
>UniRef100_B6JY06 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6JY06_SCHJY
Length = 626
Score = 96.3 bits (238), Expect = 1e-18
Identities = 42/95 (44%), Positives = 61/95 (64%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P ITY+A N + +N NAVTWGVFP +++IQ TI+ P SF+ W+DEA+ IW
Sbjct: 523 PQITYLAGNNKGEFKTNASLDSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWG- 581
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
WA LYP PS KL++ + +LVS++ N+++
Sbjct: 582 EWARLYPAGTPSHKLIQSCIDNCWLVSVIHHNFLD 616
[66][TOP]
>UniRef100_A8N945 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8N945_COPC7
Length = 574
Score = 95.9 bits (237), Expect = 1e-18
Identities = 48/102 (47%), Positives = 67/102 (65%), Gaps = 1/102 (0%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+ITY +NK + +N NAVTWGVFP K++IQPTIV+ SF WKDEA+E+ ++
Sbjct: 442 NITYHVINKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ- 500
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD-IFSVF 167
WA LY D PS+KL+ + +Y LV++V ++ N D IF F
Sbjct: 501 WARLYEHDSPSQKLILNLMENYALVNVVHNDFHNPDAIFEPF 542
[67][TOP]
>UniRef100_B8M3Q9 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8M3Q9_TALSN
Length = 607
Score = 95.5 bits (236), Expect = 2e-18
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY VNK+ + E NAVTWG+F +K++IQPTIV+ SF WKDEA+++
Sbjct: 481 PDLTYYCVNKTGELKARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GE 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA +P D PSRKL++ V +Y++++V+ ++ N DIF +F
Sbjct: 539 DWAKCHPADSPSRKLIQRVMDEWYILNIVNNDFHKNDDIFRLF 581
[68][TOP]
>UniRef100_UPI000023D9F4 hypothetical protein FG09572.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023D9F4
Length = 621
Score = 94.7 bits (234), Expect = 3e-18
Identities = 45/93 (48%), Positives = 60/93 (64%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV K SN+ NAVTWGVFP K+++QPTIV+ SF WKDEAF +
Sbjct: 480 PDLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GV 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA+ Y PSR LLE V + +YLV++V+ ++
Sbjct: 539 DWAHCYDISSPSRALLEGVMNDWYLVNIVNNDF 571
[69][TOP]
>UniRef100_B6QPH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QPH8_PENMQ
Length = 607
Score = 94.7 bits (234), Expect = 3e-18
Identities = 45/103 (43%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY +NK+ + E NAVTWG+F +K++IQPTIV+ SF WKDEA+++
Sbjct: 481 PDLTYYCINKTGELRARSDEGP-NAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQL-GD 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA +P D PSRKLL+ V +Y++++V+ ++ N DIF +F
Sbjct: 539 DWAKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKNDDIFRLF 581
[70][TOP]
>UniRef100_Q4P1E8 Methylenetetrahydrofolate reductase n=1 Tax=Ustilago maydis
RepID=Q4P1E8_USTMA
Length = 684
Score = 94.4 bits (233), Expect = 4e-18
Identities = 39/91 (42%), Positives = 66/91 (72%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
ITY A N ++ SN+G+ + N VTW VFP K+++Q TI++ SF+ W++EAFEIW+ W
Sbjct: 583 ITYFAGNAKGDFQSNLGDEEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWA-EW 641
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
+ L+P+ SR+L++E++ + +LV++V +Y
Sbjct: 642 SLLFPKKSASRQLIDEIREARWLVTVVHHDY 672
[71][TOP]
>UniRef100_B0CU22 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CU22_LACBS
Length = 602
Score = 94.0 bits (232), Expect = 5e-18
Identities = 46/102 (45%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+ITY +NK + +N NAVTWGVFP K+++QPTIV+ SF WKDEAFE+ +
Sbjct: 482 NITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFEL-GQQ 540
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD-IFSVF 167
WA LY + PS+KL+ E+ + +LV++V ++ D IF F
Sbjct: 541 WAKLYEANSPSQKLITELMDTCFLVNVVHNDFHEPDAIFKPF 582
[72][TOP]
>UniRef100_B7G287 Methylenetetrahydrofolate reductase n=1 Tax=Phaeodactylum
tricornutum CCAP 1055/1 RepID=B7G287_PHATR
Length = 634
Score = 93.6 bits (231), Expect = 6e-18
Identities = 43/103 (41%), Positives = 64/103 (62%), Gaps = 1/103 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKD 317
V K S+ AVN + N + E V A+TWGVFP ++++QPTI DP F VW +
Sbjct: 513 VNMVKQNQSMNVYAVNNAGNCIQEGTELGGVTALTWGVFPNREILQPTIFDPRIFLVWAE 572
Query: 316 EAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
EAF +W+ W+NLY D S L+E ++ +YYL +++D +YI+
Sbjct: 573 EAFSLWTSMWSNLYDYDSDSFDLIETIRDTYYLCAIIDNDYIS 615
[73][TOP]
>UniRef100_C7Z4M2 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7Z4M2_NECH7
Length = 618
Score = 93.2 bits (230), Expect = 8e-18
Identities = 46/102 (45%), Positives = 65/102 (63%), Gaps = 1/102 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +T+ AV K SN NAVTWGVFP K+++QPTIV+ SF WKDEAF +
Sbjct: 480 PDLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRL-GV 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSV 170
WA+ Y + PSR L++EV + +YLV++V+ ++ N IF +
Sbjct: 539 DWAHCYDANSPSRALIDEVMNEWYLVNIVNNDFHQNATIFEL 580
[74][TOP]
>UniRef100_Q6CG63 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CG63_YARLI
Length = 583
Score = 92.8 bits (229), Expect = 1e-17
Identities = 48/111 (43%), Positives = 73/111 (65%), Gaps = 1/111 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
V+K + IT+ AVNK+ N +N NAVTWG++P K+VIQPTIV+ SF WK+E
Sbjct: 473 VKKLENQSEITFYAVNKTGNLQTN-APGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEE 531
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVFA 164
AF + S WA YP + SRK L+++ +++YLV++V ++ + IF +F+
Sbjct: 532 AFRLGS-EWAKCYPAESESRKFLDDIFNNWYLVNIVHNDFHDSTGIFDLFS 581
[75][TOP]
>UniRef100_B8BRT9 Methylenetetrahydrofolate reductase (Fragment) n=1
Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRT9_THAPS
Length = 574
Score = 92.0 bits (227), Expect = 2e-17
Identities = 39/94 (41%), Positives = 61/94 (64%), Gaps = 1/94 (1%)
Frame = -1
Query: 472 PSITYMAVNKSENWVS-NIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
PS+ AVN + + + E V A+TWGVFP ++++QPTI DP +F +W +EAF +W
Sbjct: 481 PSLNMYAVNNAGQELRVGVEEGGVTALTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWG 540
Query: 295 RSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
W NLY S L++E++ +YYLV+L+D ++
Sbjct: 541 SMWLNLYEYGSESYDLVQEIRDTYYLVALIDNDF 574
[76][TOP]
>UniRef100_Q1DNB1 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DNB1_COCIM
Length = 629
Score = 92.0 bits (227), Expect = 2e-17
Identities = 46/103 (44%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY A+NK+ +N +S NAVTWG+F +K+VIQPTIV+ SF WKDEAF +
Sbjct: 480 PDLTYYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GD 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA + PSR+L++ V +YLV++V+ ++ DIF++F
Sbjct: 538 DWAKCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFNLF 580
[77][TOP]
>UniRef100_A4RJT6 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RJT6_MAGGR
Length = 626
Score = 92.0 bits (227), Expect = 2e-17
Identities = 41/93 (44%), Positives = 62/93 (66%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV KS N +N NAVTWGVFP K+++QPT+V+ SF WKDEAF++
Sbjct: 475 PDLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQL-GM 533
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA + ++ PSR L++ + +YLV++V+ ++
Sbjct: 534 EWARCHDQNTPSRILIQSMMQEWYLVNIVNNDF 566
[78][TOP]
>UniRef100_Q10258 Methylenetetrahydrofolate reductase 1 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR1_SCHPO
Length = 603
Score = 92.0 bits (227), Expect = 2e-17
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
Frame = -1
Query: 490 EKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEA 311
E K + S++Y NK+ + +N NAVTWGVFP +++IQPTIV+ SF WKDEA
Sbjct: 477 ETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEA 536
Query: 310 FEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
+ + WAN Y D SRKLL + ++L +VD ++ NG +F VF
Sbjct: 537 YSL-GMEWANAYSPDSISRKLLVSMMKEWFLCVIVDNDFQNGQSLFDVF 584
[79][TOP]
>UniRef100_C5PJM0 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5PJM0_COCP7
Length = 629
Score = 91.7 bits (226), Expect = 2e-17
Identities = 46/103 (44%), Positives = 67/103 (65%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY A+NK+ +N +S NAVTWG+F +K+VIQPTIV+ SF WKDEAF +
Sbjct: 480 PDLTYYAINKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRL-GD 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA + PSR+L++ V +YLV++V+ ++ DIF +F
Sbjct: 538 DWAKCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLF 580
[80][TOP]
>UniRef100_C4Y9Q4 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y9Q4_CLAL4
Length = 601
Score = 91.7 bits (226), Expect = 2e-17
Identities = 44/103 (42%), Positives = 63/103 (61%), Gaps = 2/103 (1%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGE--SDVNAVTWGVFPAKQVIQPTIVDPASFKVWK 320
++K + +ITY N +N+ S A+TWGVFP+K+V+QPT++D SF+ W
Sbjct: 489 MDKDISDKTITYFCGNSKGEITTNMPHKSSQRTAITWGVFPSKEVLQPTVIDRQSFQAWN 548
Query: 319 DEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYI 191
+EAF +W WA Y D PS +LL + S YYLVS+V NY+
Sbjct: 549 EEAFGLW-LDWARCYAPDSPSYRLLAGIHSDYYLVSIVHNNYL 590
[81][TOP]
>UniRef100_A8Q9P3 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8Q9P3_MALGO
Length = 515
Score = 91.7 bits (226), Expect = 2e-17
Identities = 45/100 (45%), Positives = 63/100 (63%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+ + A P ITY AVN + +N NAVTWG FP +++QPTIV+ SF WKDE
Sbjct: 399 IARFDAHPQITYHAVNAQGDMRTNTTSDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDE 458
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
A+EI R WA Y + P+R+LLE V +Y+LV++V ++
Sbjct: 459 AYEI-GRRWAAFYEPESPTRRLLEHVFDTYFLVNVVHNDF 497
[82][TOP]
>UniRef100_Q0U6C4 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0U6C4_PHANO
Length = 657
Score = 90.9 bits (224), Expect = 4e-17
Identities = 46/119 (38%), Positives = 71/119 (59%), Gaps = 1/119 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P TY AVNK + +N NAVTWGVFP K+++QPTIV+ SF WKDE + + +
Sbjct: 480 PEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQ 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVFA*SPRKPPAKRNHSIS 119
WAN + PSR ++++V ++YL+++V ++ IF +F K K+ HS++
Sbjct: 539 QWANCHGGASPSRFVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLQVKDIDKKLHSVN 597
[83][TOP]
>UniRef100_C1GYS1 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1GYS1_PARBA
Length = 629
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/101 (43%), Positives = 68/101 (67%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY VNK+ +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A +P PSR+L+++V ++YLV++V+ ++ DIF +F
Sbjct: 540 AKCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLF 580
[84][TOP]
>UniRef100_C0RZ73 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0RZ73_PARBP
Length = 629
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/101 (43%), Positives = 68/101 (67%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY VNK+ +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYCVNKTGELRTNTSDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A +P PSR+L+++V ++YLV++V+ ++ DIF +F
Sbjct: 540 AKCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLF 580
[85][TOP]
>UniRef100_C0NNE8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NNE8_AJECG
Length = 633
Score = 90.5 bits (223), Expect = 5e-17
Identities = 44/103 (42%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY VNK +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ +
Sbjct: 480 PDLTYYCVNKKGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GD 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA + PSR+++++V S+YLV++V+ ++ DIF++F
Sbjct: 538 DWAKCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIF 580
[86][TOP]
>UniRef100_Q4X140 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4X140_ASPFU
Length = 615
Score = 90.1 bits (222), Expect = 7e-17
Identities = 42/103 (40%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV K+ +N +S NA+TWG+F ++++QPTIVD SF WKDEA+ +
Sbjct: 480 PDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GE 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
WA + PSRKL++++ ++YLV++V+ ++ N D+F +F
Sbjct: 538 DWAKCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLF 580
[87][TOP]
>UniRef100_B0XSG0 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0XSG0_ASPFC
Length = 615
Score = 90.1 bits (222), Expect = 7e-17
Identities = 42/103 (40%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV K+ +N +S NA+TWG+F ++++QPTIVD SF WKDEA+ +
Sbjct: 480 PDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVDTISFLAWKDEAYRL-GE 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
WA + PSRKL++++ ++YLV++V+ ++ N D+F +F
Sbjct: 538 DWAKCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLF 580
[88][TOP]
>UniRef100_O74927 Methylenetetrahydrofolate reductase 2 n=1 Tax=Schizosaccharomyces
pombe RepID=MTHR2_SCHPO
Length = 641
Score = 90.1 bits (222), Expect = 7e-17
Identities = 38/95 (40%), Positives = 63/95 (66%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY A N +++N + +AVTWGV+P +++IQ TI+ SFK W E+F++W
Sbjct: 536 PQVTYYAGNNKSEFLTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWG- 594
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
WANLY ++ PSRKLLE + +LV+++ ++++
Sbjct: 595 EWANLYSKNTPSRKLLENCINDRWLVTVIHHDFMD 629
[89][TOP]
>UniRef100_C6H337 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6H337_AJECH
Length = 524
Score = 89.7 bits (221), Expect = 9e-17
Identities = 44/103 (42%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY VNK +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ +
Sbjct: 371 PDLTYYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GD 428
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA + PSR+++++V S+YLV++V+ ++ DIF++F
Sbjct: 429 DWAKCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIF 471
[90][TOP]
>UniRef100_C5DPF1 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5DPF1_ZYGRC
Length = 650
Score = 89.7 bits (221), Expect = 9e-17
Identities = 43/95 (45%), Positives = 57/95 (60%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A + N+ +N+ + N VTWGVF QVIQ TIV SFK W DEAF IW W
Sbjct: 549 LTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEAFSIW-LEW 607
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
A L+P + + LL ++ Y L+S+V +YIN D
Sbjct: 608 AKLFPRNTSTNSLLRQIHQEYCLISIVHHDYINPD 642
[91][TOP]
>UniRef100_C1G7L7 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1G7L7_PARBD
Length = 629
Score = 89.7 bits (221), Expect = 9e-17
Identities = 44/101 (43%), Positives = 68/101 (67%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY VNK+ +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYCVNKTGELRTNTTDSP-NAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A +P PSR+L+++V ++YLV++V+ ++ DIF +F
Sbjct: 540 AKCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLF 580
[92][TOP]
>UniRef100_A7EWQ5 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7EWQ5_SCLS1
Length = 590
Score = 89.7 bits (221), Expect = 9e-17
Identities = 42/93 (45%), Positives = 59/93 (63%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV K+ + +N NAVTWGVFP K+++QPTIV+ SF WKDEAF +
Sbjct: 480 PDLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRL-GT 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WA+ + PSR L+E + S+YLV++ N+
Sbjct: 539 DWAHCHSALSPSRGLIESIMDSWYLVNIGRANF 571
[93][TOP]
>UniRef100_Q8MQE7 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis elegans
RepID=Q8MQE7_CAEEL
Length = 642
Score = 89.4 bits (220), Expect = 1e-16
Identities = 37/92 (40%), Positives = 60/92 (65%), Gaps = 1/92 (1%)
Frame = -1
Query: 466 ITYMAVNKSENW-VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+ Y A+NK + +N E+ AVTWGVFP ++ QPT+VDP SF+ W+DEA+++W
Sbjct: 532 VNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQ 591
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
W + YP++ S +++ V + LV+LVD ++
Sbjct: 592 WGDFYPKESKSYGVIKAVHDEFRLVTLVDNDF 623
[94][TOP]
>UniRef100_A8NEV2 Methylenetetrahydrofolate reductase n=1 Tax=Coprinopsis cinerea
okayama7#130 RepID=A8NEV2_COPC7
Length = 617
Score = 89.4 bits (220), Expect = 1e-16
Identities = 44/107 (41%), Positives = 64/107 (59%)
Frame = -1
Query: 487 KSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAF 308
K + + Y N + SN+ E NAVTWGVFP +++ Q TI++ SF WKDEA+
Sbjct: 503 KQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAY 562
Query: 307 EIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFSVF 167
+IW+ SWA+LY D R+LL++V + +LVS+V Y N + F
Sbjct: 563 DIWN-SWASLYHPDSAERQLLQKVANERWLVSIVHHEYKNPNALWTF 608
[95][TOP]
>UniRef100_Q17693 Probable methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis
elegans RepID=MTHR_CAEEL
Length = 663
Score = 89.4 bits (220), Expect = 1e-16
Identities = 37/92 (40%), Positives = 60/92 (65%), Gaps = 1/92 (1%)
Frame = -1
Query: 466 ITYMAVNKSENW-VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+ Y A+NK + +N E+ AVTWGVFP ++ QPT+VDP SF+ W+DEA+++W
Sbjct: 553 VNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQ 612
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
W + YP++ S +++ V + LV+LVD ++
Sbjct: 613 WGDFYPKESKSYGVIKAVHDEFRLVTLVDNDF 644
[96][TOP]
>UniRef100_A8PV87 Methylenetetrahydrofolate reductase n=1 Tax=Brugia malayi
RepID=A8PV87_BRUMA
Length = 656
Score = 88.6 bits (218), Expect = 2e-16
Identities = 39/69 (56%), Positives = 52/69 (75%)
Frame = -1
Query: 400 AVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYY 221
AVTWGVFP ++ QPT+VDP SF+VWKDEAF W +W+++Y E SR LLE++ + Y
Sbjct: 573 AVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAW-LNWSSIYAEGTSSRCLLEKIYNEYC 631
Query: 220 LVSLVDTNY 194
LV+LVD +Y
Sbjct: 632 LVTLVDNDY 640
[97][TOP]
>UniRef100_A6RBU9 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6RBU9_AJECN
Length = 619
Score = 88.6 bits (218), Expect = 2e-16
Identities = 43/103 (41%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY VNK +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ +
Sbjct: 466 PDLTYYCVNKIGELRTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GD 523
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
WA + PSR+++++V ++YLV++V+ ++ DIF++F
Sbjct: 524 DWAKCHGASSPSRRIIQQVMDNWYLVNIVNNDFHKTHDIFNIF 566
[98][TOP]
>UniRef100_A1DH45 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1DH45_NEOFI
Length = 615
Score = 88.6 bits (218), Expect = 2e-16
Identities = 41/103 (39%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV K+ +N +S NA+TWG+F ++++QPTIV+ SF WKDEA+ +
Sbjct: 480 PDLTYHAVAKNRELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GE 537
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
WA + PSRKL++++ ++YLV++V+ ++ N D+F +F
Sbjct: 538 DWAKCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLF 580
[99][TOP]
>UniRef100_UPI0000123E6B Hypothetical protein CBG12960 n=1 Tax=Caenorhabditis briggsae AF16
RepID=UPI0000123E6B
Length = 662
Score = 88.2 bits (217), Expect = 3e-16
Identities = 35/92 (38%), Positives = 62/92 (67%), Gaps = 1/92 (1%)
Frame = -1
Query: 466 ITYMAVNKSENW-VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+ Y A++K ++ +N E+ AVTWGVFP ++ QPT+VDP SF+ W+DEA+++W
Sbjct: 554 VNYHAIDKDSSFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQ 613
Query: 289 WANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
W + YP++ S +++ + ++ LV+LVD ++
Sbjct: 614 WGDFYPKESKSYGVIKSIHDTFRLVTLVDNDF 645
[100][TOP]
>UniRef100_A4RH85 Methylenetetrahydrofolate reductase n=1 Tax=Magnaporthe grisea
RepID=A4RH85_MAGGR
Length = 662
Score = 87.8 bits (216), Expect = 3e-16
Identities = 36/74 (48%), Positives = 54/74 (72%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
S NAVTWGVFP K+++ PTI++ SF+ W +EAF IW+ WA +Y +D PS KLLE ++
Sbjct: 579 SSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWA-EWAKVYGKDSPSEKLLESLR 637
Query: 232 SSYYLVSLVDTNYI 191
+ +LV+++ +YI
Sbjct: 638 ADLWLVNIIHHDYI 651
[101][TOP]
>UniRef100_Q6CR34 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CR34_KLULA
Length = 649
Score = 87.4 bits (215), Expect = 4e-16
Identities = 39/82 (47%), Positives = 54/82 (65%)
Frame = -1
Query: 427 SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
+N+ NAVTWGVFP +V+Q TIV+ SFK W+DEAF IW W+ L+P++ P
Sbjct: 561 TNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWI-EWSKLFPKNTPENTF 619
Query: 247 LEEVKSSYYLVSLVDTNYINGD 182
L ++ YYLVS+V ++IN D
Sbjct: 620 LRKMHRDYYLVSIVHHDFINPD 641
[102][TOP]
>UniRef100_C8UZX0 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5B0P7] n=2 Tax=Emericella
nidulans RepID=C8UZX0_EMENI
Length = 627
Score = 87.4 bits (215), Expect = 4e-16
Identities = 43/110 (39%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+ + +A +TY AV K +N +S NA+TWG+F ++V+QPTIV+ SF WKDE
Sbjct: 473 IARIEANEDLTYHAVTKKGELRTNTRDSP-NALTWGIFAGREVVQPTIVETVSFLAWKDE 531
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
A+++ WA + P+RKLL+ + S+YLV++V+ ++ N D+F +F
Sbjct: 532 AYQL-GEDWAKCHEASSPTRKLLQGIMDSWYLVNIVNNDFHNTYDLFELF 580
[103][TOP]
>UniRef100_B2WMV1 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WMV1_PYRTR
Length = 646
Score = 87.4 bits (215), Expect = 4e-16
Identities = 38/93 (40%), Positives = 60/93 (64%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P TY AVNK + +N NAVTWGVFP K+++QPTIV+ SF WKDE + + +
Sbjct: 480 PEFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRL-GQ 538
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WAN + PSR +++++ ++YL+++V ++
Sbjct: 539 QWANCHAGVSPSRYVIQDIVDTWYLLNIVHNDF 571
[104][TOP]
>UniRef100_Q4T956 Methylenetetrahydrofolate reductase n=1 Tax=Tetraodon nigroviridis
RepID=Q4T956_TETNG
Length = 845
Score = 87.0 bits (214), Expect = 6e-16
Identities = 34/79 (43%), Positives = 51/79 (64%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P + Y VN ++N + NAVTWG+F ++++QPT+VDP SF WKDEAF +W
Sbjct: 538 PRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIE 597
Query: 292 SWANLYPEDDPSRKLLEEV 236
WA LY ++ PSR +++ +
Sbjct: 598 QWAKLYEDESPSRMIIQYI 616
[105][TOP]
>UniRef100_C4JG55 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JG55_UNCRE
Length = 625
Score = 86.7 bits (213), Expect = 8e-16
Identities = 44/101 (43%), Positives = 65/101 (64%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A NK+ +N +S NAVTWG+F +K+VIQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYATNKNGELKTNTSDSP-NAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A + PSR+L++ V +YLV++V+ ++ DIF +F
Sbjct: 540 AKCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLF 580
[106][TOP]
>UniRef100_A5DE00 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DE00_PICGU
Length = 642
Score = 86.7 bits (213), Expect = 8e-16
Identities = 43/96 (44%), Positives = 59/96 (61%), Gaps = 5/96 (5%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNI-----GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI 302
ITY A + S SN+ + NAVTWGVFP+++V+QPTI+D SF+ W +EAF +
Sbjct: 536 ITYYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHL 595
Query: 301 WSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
WS WA Y ++ S LL + YYLVSL+ N+
Sbjct: 596 WS-EWARCYKKNSVSYNLLNSINGDYYLVSLIYHNF 630
[107][TOP]
>UniRef100_A1C6H3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C6H3_ASPCL
Length = 619
Score = 86.3 bits (212), Expect = 1e-15
Identities = 43/101 (42%), Positives = 66/101 (65%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY AV K +N +S NA+TWG+F ++++QPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYHAVAKEGELRTNTRDSP-NALTWGIFAGREIVQPTIVETISFLAWKDEAYRL-GEDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
A + PSRKL++EV S+YLV++V+ ++ N D+F +F
Sbjct: 540 AKCHEAASPSRKLIQEVVDSWYLVNIVNNDFHNTYDLFELF 580
[108][TOP]
>UniRef100_A8XGR9 Methylenetetrahydrofolate reductase n=1 Tax=Caenorhabditis briggsae
RepID=A8XGR9_CAEBR
Length = 724
Score = 85.9 bits (211), Expect = 1e-15
Identities = 35/102 (34%), Positives = 63/102 (61%), Gaps = 11/102 (10%)
Frame = -1
Query: 466 ITYMAVNKSENWV-----------SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWK 320
+ Y A++K +++ +N E+ AVTWGVFP ++ QPT+VDP SF+ W+
Sbjct: 604 VNYHAIDKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWR 663
Query: 319 DEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
DEA+++W W + YP++ S +++ + ++ LV+LVD ++
Sbjct: 664 DEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDF 705
[109][TOP]
>UniRef100_Q0CXY7 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CXY7_ASPTN
Length = 619
Score = 85.9 bits (211), Expect = 1e-15
Identities = 43/110 (39%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+EK++ +TY AV+K+ +N +S NA+TWG+F ++V+QPTIV+ SF WKDE
Sbjct: 476 IEKNE---DLTYHAVSKTGELRTNTRDSP-NALTWGIFAGREVVQPTIVETISFLAWKDE 531
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
A+ + WA + PSRKL+++V ++YLV++V+ ++ N ++F +F
Sbjct: 532 AYRL-GEDWAKCHEAGSPSRKLIQDVMDNWYLVNIVNNDFHNSFNLFELF 580
[110][TOP]
>UniRef100_C5DIA7 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5DIA7_LACTC
Length = 660
Score = 85.9 bits (211), Expect = 1e-15
Identities = 39/95 (41%), Positives = 61/95 (64%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
++Y + +E + +N+ S + VTWGVFP +V+Q TIV+ SFK W+DEAF IW W
Sbjct: 559 VSYYVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIW-LEW 617
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
+ L+P + S LL+++ YYLVS+V ++ + D
Sbjct: 618 SKLFPRNSRSNTLLKQMHRDYYLVSIVHHDFSDCD 652
[111][TOP]
>UniRef100_C5FFF6 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FFF6_NANOT
Length = 623
Score = 85.5 bits (210), Expect = 2e-15
Identities = 41/110 (37%), Positives = 68/110 (61%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDE 314
+ + + P +TY +NK+ +N ++ NAVTWG+F +K+VIQPTIV+ SF WKDE
Sbjct: 473 IRRIETNPDLTYHCINKNGELRTNSSDTP-NAVTWGIFASKEVIQPTIVETVSFLAWKDE 531
Query: 313 AFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A+ + WA + PSRK+++ ++YL ++V+ ++ DIF +F
Sbjct: 532 AYRL-GDDWAKCHDASSPSRKIIQNTMDTWYLFNIVNNDFHKTHDIFDLF 580
[112][TOP]
>UniRef100_UPI000023F2EE hypothetical protein FG07127.1 n=1 Tax=Gibberella zeae PH-1
RepID=UPI000023F2EE
Length = 672
Score = 85.1 bits (209), Expect = 2e-15
Identities = 37/74 (50%), Positives = 50/74 (67%)
Frame = -1
Query: 403 NAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSY 224
NAVTWGVFP K++I PTI++ SF+ W +EAF IW WA +Y S KLL +K Y
Sbjct: 592 NAVTWGVFPGKEIITPTIIEEVSFRAWCEEAFGIWG-EWAKVYGRGSESEKLLNGIKDDY 650
Query: 223 YLVSLVDTNYINGD 182
+LV+L+ +Y+N D
Sbjct: 651 WLVNLIHHDYVNRD 664
[113][TOP]
>UniRef100_C5JE18 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis SLH14081 RepID=C5JE18_AJEDS
Length = 633
Score = 84.7 bits (208), Expect = 3e-15
Identities = 43/101 (42%), Positives = 66/101 (65%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY VNK +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A + SR+L+E+V ++YLV++V+ ++ DIF++F
Sbjct: 540 AKCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLF 580
[114][TOP]
>UniRef100_C5GPB7 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces
dermatitidis ER-3 RepID=C5GPB7_AJEDR
Length = 633
Score = 84.7 bits (208), Expect = 3e-15
Identities = 43/101 (42%), Positives = 66/101 (65%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY VNK +N +S NAVTWG+F +K++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYYCVNKKGELKTNTTDSP-NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY-INGDIFSVF 167
A + SR+L+E+V ++YLV++V+ ++ DIF++F
Sbjct: 540 AKCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLF 580
[115][TOP]
>UniRef100_B8NG74 Methylenetetrahydrofolate reductase n=2 Tax=Aspergillus
RepID=B8NG74_ASPFN
Length = 612
Score = 84.7 bits (208), Expect = 3e-15
Identities = 42/101 (41%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY AV+K+ +N +S NA+TWG+F ++V+QPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYHAVSKNGELRTNTHDSP-NALTWGIFAGREVVQPTIVETISFLAWKDEAYRL-GEDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYING-DIFSVF 167
A + PSRKL++ + S+YLV++V+ ++ N D+F +F
Sbjct: 540 AKCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELF 580
[116][TOP]
>UniRef100_Q7S2B6 Methylenetetrahydrofolate reductase n=1 Tax=Neurospora crassa
RepID=Q7S2B6_NEUCR
Length = 681
Score = 84.3 bits (207), Expect = 4e-15
Identities = 35/78 (44%), Positives = 54/78 (69%)
Frame = -1
Query: 415 ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
E NAVTWGVFP K+++ PTI++ SF+ W +EAF IWS WA +Y + ++KLLE++
Sbjct: 597 EPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWS-EWAKIYGKGSDTQKLLEDL 655
Query: 235 KSSYYLVSLVDTNYINGD 182
K +LV+++ +Y+ D
Sbjct: 656 KEDLWLVNVIHHDYLEKD 673
[117][TOP]
>UniRef100_C5M851 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M851_CANTT
Length = 609
Score = 84.3 bits (207), Expect = 4e-15
Identities = 38/102 (37%), Positives = 66/102 (64%), Gaps = 7/102 (6%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
I+Y AVNK+ N +SN + D+NAVTWGVFP ++++QPTIV+ SF WKDE + ++S W
Sbjct: 496 ISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYTLFS-EW 554
Query: 286 ANLYPEDDPSR-------KLLEEVKSSYYLVSLVDTNYINGD 182
+ + D + +L+ ++ ++ L +LV+ +++ G+
Sbjct: 555 SKISGMFDAEKDKIQHFNELMSQITENFVLCNLVNNDFLQGN 596
[118][TOP]
>UniRef100_B2B6X0 Methylenetetrahydrofolate reductase n=1 Tax=Podospora anserina
RepID=B2B6X0_PODAN
Length = 691
Score = 84.3 bits (207), Expect = 4e-15
Identities = 34/78 (43%), Positives = 54/78 (69%)
Frame = -1
Query: 415 ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
E+ NAVTWGVFP K+++ PTI++ SF+ W +EAF IW WA +Y + S KLLE++
Sbjct: 607 EASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWG-EWAKIYGKGSESEKLLEKI 665
Query: 235 KSSYYLVSLVDTNYINGD 182
+ +LV+++ ++I+ D
Sbjct: 666 RGDSWLVNIIHHDFIDSD 683
[119][TOP]
>UniRef100_B0CSW4 Methylenetetrahydrofolate reductase n=1 Tax=Laccaria bicolor
S238N-H82 RepID=B0CSW4_LACBS
Length = 602
Score = 84.3 bits (207), Expect = 4e-15
Identities = 40/78 (51%), Positives = 52/78 (66%)
Frame = -1
Query: 427 SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
SN+ E NAVTWGVFP +++ Q TI++ SF WKDEAF IWS WA+ Y RKL
Sbjct: 510 SNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWS-EWASFYRPGSEERKL 568
Query: 247 LEEVKSSYYLVSLVDTNY 194
LE V++ +LVS+V +Y
Sbjct: 569 LEGVRNERWLVSIVHHDY 586
[120][TOP]
>UniRef100_Q5A5S8 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5A5S8_CANAL
Length = 640
Score = 84.0 bits (206), Expect = 5e-15
Identities = 41/99 (41%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIG-----ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
++TY NK SN+ + NAVTWGVFP+K+V+QPT++D SFK W +EAF
Sbjct: 532 TVTYYVGNKDGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFL 591
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
+W WA Y ++ S +LL + +Y LVS++ ++IN
Sbjct: 592 LW-LEWARCYKKNSKSFELLNSIYENYVLVSMIHHDFIN 629
[121][TOP]
>UniRef100_C4YKV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=C4YKV3_CANAL
Length = 640
Score = 84.0 bits (206), Expect = 5e-15
Identities = 41/99 (41%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIG-----ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
++TY NK SN+ + NAVTWGVFP+K+V+QPT++D SFK W +EAF
Sbjct: 532 TVTYYVGNKDGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFL 591
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
+W WA Y ++ S +LL + +Y LVS++ ++IN
Sbjct: 592 LW-LEWARCYKKNSKSFELLNSIYENYVLVSMIHHDFIN 629
[122][TOP]
>UniRef100_A7TRT4 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TRT4_VANPO
Length = 645
Score = 84.0 bits (206), Expect = 5e-15
Identities = 42/94 (44%), Positives = 59/94 (62%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y + S ++ SN+ + N VTWGVFP VIQ TIV+ SFK W+DEAF IW WA
Sbjct: 545 SYYVGDSSGSFESNLETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIW-LEWA 603
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P ++ S L++V S+Y LVS+V ++ D
Sbjct: 604 KLFPSNELSNSFLKQVHSTYCLVSIVHHDFSETD 637
[123][TOP]
>UniRef100_UPI000151A866 hypothetical protein PGUG_01501 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151A866
Length = 642
Score = 83.6 bits (205), Expect = 6e-15
Identities = 42/96 (43%), Positives = 57/96 (59%), Gaps = 5/96 (5%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNI-----GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI 302
ITY A + S SN+ + NAVTWGVFP ++V+QPTI+D SF+ W +EAF +
Sbjct: 536 ITYYAGDSSGKIQSNLPVGPDSHNSKNAVTWGVFPLQEVLQPTIIDIESFRAWNEEAFHL 595
Query: 301 WSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
W WA Y ++ S LL + YYLVSL+ N+
Sbjct: 596 W-LEWARCYKKNSVSYNLLNSINGDYYLVSLIYHNF 630
[124][TOP]
>UniRef100_C5E2N6 Methylenetetrahydrofolate reductase n=1 Tax=Lachancea
thermotolerans CBS 6340 RepID=C5E2N6_LACTC
Length = 599
Score = 83.6 bits (205), Expect = 6e-15
Identities = 43/99 (43%), Positives = 65/99 (65%), Gaps = 3/99 (3%)
Frame = -1
Query: 475 IPSITYMAVNKSENWVSNI-GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIW 299
+PS+TY AV+ ++ SN ++ NAVTWG+FP ++V+QPTIV+ SF WK+E F+I
Sbjct: 489 MPSLTYFAVDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFFDIL 548
Query: 298 SRSWANLYPEDDPSRK--LLEEVKSSYYLVSLVDTNYIN 188
W + E++ S LLE V S Y LV++VD +Y++
Sbjct: 549 D-EWKRIMGENNHSESVALLESVISDYLLVNIVDNDYVS 586
[125][TOP]
>UniRef100_A7E9M9 Methylenetetrahydrofolate reductase n=1 Tax=Sclerotinia
sclerotiorum 1980 UF-70 RepID=A7E9M9_SCLS1
Length = 663
Score = 83.2 bits (204), Expect = 8e-15
Identities = 37/99 (37%), Positives = 65/99 (65%), Gaps = 3/99 (3%)
Frame = -1
Query: 469 SITYMAVNKSENWVSN---IGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIW 299
++++ A N +++S+ IG + NAVTWG FP K++I PTI++ SF+ W +EAF IW
Sbjct: 560 TVSFYASNAKGDFISSDEAIGST--NAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIW 617
Query: 298 SRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
WA +Y +D +RK+++ +K +LV+++ Y+ G+
Sbjct: 618 G-EWARVYGKDSETRKVIDGIKEDVWLVNVIHHAYVEGE 655
[126][TOP]
>UniRef100_A6RQJ7 Methylenetetrahydrofolate reductase n=1 Tax=Botryotinia fuckeliana
B05.10 RepID=A6RQJ7_BOTFB
Length = 663
Score = 83.2 bits (204), Expect = 8e-15
Identities = 35/97 (36%), Positives = 62/97 (63%), Gaps = 1/97 (1%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNI-GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
++++ A N +++S+ NAVTWG FP K++I PTI++ SF+ W +EAF IW
Sbjct: 560 TVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWG- 618
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
WA +Y +D +RK+++ +K +LV+++ Y+ G+
Sbjct: 619 EWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGE 655
[127][TOP]
>UniRef100_B9WCV3 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WCV3_CANDC
Length = 640
Score = 82.4 bits (202), Expect = 1e-14
Identities = 40/99 (40%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNI-----GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
++TY +K SN+ + NAVTWGVFP+K+V+QPT++D SFK W +EAF
Sbjct: 532 TVTYYVGDKDGEIRSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFL 591
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
+W WA Y ++ S +LL + +Y LVS++ ++IN
Sbjct: 592 LWV-EWARCYKKNSKSFELLNSIYENYVLVSIIHHDFIN 629
[128][TOP]
>UniRef100_C7YTQ6 Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4
RepID=C7YTQ6_NECH7
Length = 674
Score = 81.6 bits (200), Expect = 2e-14
Identities = 42/114 (36%), Positives = 63/114 (55%), Gaps = 10/114 (8%)
Frame = -1
Query: 493 VEKSKAIPSITYMAVNKSENWVSNIGESDV----------NAVTWGVFPAKQVIQPTIVD 344
+ S+ S+ + A N ++VS+ V NAVTWGVFP K++I PTI++
Sbjct: 554 LNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSGAGPSTNAVTWGVFPGKEIITPTIIE 613
Query: 343 PASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
SF+ W +EAF IW WA +Y S KLL +K Y+LV+L+ +++ D
Sbjct: 614 EVSFRAWCEEAFGIWG-EWAKVYGRGSDSEKLLSGIKDEYWLVNLIHHDFVEKD 666
[129][TOP]
>UniRef100_A2QCE3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QCE3_ASPNC
Length = 626
Score = 81.6 bits (200), Expect = 2e-14
Identities = 39/101 (38%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY AV+K+ +N +S NA+TWG+F ++++QPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYHAVSKTGELRTNTRDSP-NALTWGIFAGREIVQPTIVETVSFLAWKDEAYRL-GDDW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN-GDIFSVF 167
A + PSRKL++ V +++LV++V+ ++ N ++F +F
Sbjct: 540 AKCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLF 580
[130][TOP]
>UniRef100_Q4WEL9 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
RepID=Q4WEL9_ASPFU
Length = 689
Score = 81.3 bits (199), Expect = 3e-14
Identities = 34/73 (46%), Positives = 51/73 (69%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VNAVTWGVF K+++ PTI++ SF+ W +EAF IW W +YP P+ +LLEEVK
Sbjct: 592 NNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLEEVK 650
Query: 232 SSYYLVSLVDTNY 194
+ +LV +V ++
Sbjct: 651 NDVWLVCVVGQDF 663
[131][TOP]
>UniRef100_C5GI01 Methylenetetrahydrofolate reductase n=2 Tax=Ajellomyces
dermatitidis RepID=C5GI01_AJEDR
Length = 713
Score = 81.3 bits (199), Expect = 3e-14
Identities = 34/75 (45%), Positives = 50/75 (66%)
Frame = -1
Query: 418 GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
G + VNAVTWGVF K+++ PTI++ SF+ W DEAF IW W ++P P+ KLL++
Sbjct: 606 GGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRVFPRGSPTEKLLDQ 664
Query: 238 VKSSYYLVSLVDTNY 194
+K+ +LV +V Y
Sbjct: 665 LKNDVWLVCVVGQKY 679
[132][TOP]
>UniRef100_B0Y2U3 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus fumigatus
A1163 RepID=B0Y2U3_ASPFC
Length = 689
Score = 81.3 bits (199), Expect = 3e-14
Identities = 34/73 (46%), Positives = 51/73 (69%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VNAVTWGVF K+++ PTI++ SF+ W +EAF IW W +YP P+ +LLEEVK
Sbjct: 592 NNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLEEVK 650
Query: 232 SSYYLVSLVDTNY 194
+ +LV +V ++
Sbjct: 651 NDVWLVCVVGQDF 663
[133][TOP]
>UniRef100_A1CZX0 Methylenetetrahydrofolate reductase n=1 Tax=Neosartorya fischeri
NRRL 181 RepID=A1CZX0_NEOFI
Length = 716
Score = 81.3 bits (199), Expect = 3e-14
Identities = 34/73 (46%), Positives = 51/73 (69%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VNAVTWGVF K+++ PTI++ SF+ W +EAF IW W +YP P+ +LLEEVK
Sbjct: 619 NNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRVYPRGTPTERLLEEVK 677
Query: 232 SSYYLVSLVDTNY 194
+ +LV +V ++
Sbjct: 678 NDVWLVCVVGQDF 690
[134][TOP]
>UniRef100_Q0UB79 Methylenetetrahydrofolate reductase n=1 Tax=Phaeosphaeria nodorum
RepID=Q0UB79_PHANO
Length = 543
Score = 80.9 bits (198), Expect = 4e-14
Identities = 37/95 (38%), Positives = 60/95 (63%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A N + ++ ++ ES VN VTWG F K+++ PTI++ SF+ W +EAF IW R W
Sbjct: 443 VTYFAGNANGDFEASSEES-VNPVTWGTFAGKEIVTPTIIEAVSFRSWLEEAFSIW-REW 500
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
+YP S KLL + + +LV+++ +++ GD
Sbjct: 501 QRIYPTKSASGKLLGQTREDVWLVNVIWGDFVQGD 535
[135][TOP]
>UniRef100_B6H6J4 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6H6J4_PENCW
Length = 610
Score = 80.9 bits (198), Expect = 4e-14
Identities = 39/101 (38%), Positives = 63/101 (62%), Gaps = 1/101 (0%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A NK +N +S NA+TWG+F +++IQPTIV+ SF WKDEA+ + W
Sbjct: 482 LTYHATNKKGELKTNTRDSP-NALTWGIFAGREIIQPTIVETVSFLAWKDEAY-LLGEHW 539
Query: 286 ANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD-IFSVF 167
+ + PSR+L++ V +YLV++VD ++ + +F +F
Sbjct: 540 SKCHDAASPSRQLIQHVMEDWYLVNIVDNDFHRSNAVFELF 580
[136][TOP]
>UniRef100_A3LW82 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LW82_PICST
Length = 635
Score = 80.5 bits (197), Expect = 5e-14
Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNI-----GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
+ITY + N SN+ + NA+TWGVFP+K+V+QPTI+D SFK W +EAF
Sbjct: 528 TITYYVGDAEGNIESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFL 587
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
+W WA Y ++ + +LL + S+Y LVSL+ ++
Sbjct: 588 LWI-EWARCYKKNTKTFQLLNSIYSNYVLVSLIHHDF 623
[137][TOP]
>UniRef100_Q6CEM7 Methylenetetrahydrofolate reductase n=1 Tax=Yarrowia lipolytica
RepID=Q6CEM7_YARLI
Length = 625
Score = 80.1 bits (196), Expect = 7e-14
Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Frame = -1
Query: 451 VNKSENWV-SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLY 275
V KS+ V +N+ E N VTWGVFP ++++Q TI+ SF W++EAF IWS W LY
Sbjct: 527 VAKSDKLVDTNVSERASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWS-EWRALY 585
Query: 274 PEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
++ S KLL+++ + Y LV+++ +Y+ D
Sbjct: 586 KKNTASFKLLDKIINEYLLVTVIHHDYVEED 616
[138][TOP]
>UniRef100_Q6BM19 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=Q6BM19_DEBHA
Length = 642
Score = 80.1 bits (196), Expect = 7e-14
Identities = 39/97 (40%), Positives = 57/97 (58%), Gaps = 5/97 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIG-----ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
+ITY + SN+ + NA+TWGVFP+K+V+QPTI+D SFK W +EAF
Sbjct: 533 TITYYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFI 592
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
+W WA Y + + +LL + YYLVSL+ ++
Sbjct: 593 LW-LEWARCYKKTSKTYELLNSIYKDYYLVSLISHDF 628
[139][TOP]
>UniRef100_C7GU28 Met12p n=2 Tax=Saccharomyces cerevisiae RepID=C7GU28_YEAS2
Length = 657
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/94 (42%), Positives = 56/94 (59%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y A + S ++ +N+ + VTWGVFP V Q TI++ SFK W+DEAF IWS WA
Sbjct: 555 SYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWA 613
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + P+ LL V Y LVS+V ++ D
Sbjct: 614 KLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647
[140][TOP]
>UniRef100_B5VTD9 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VTD9_YEAS6
Length = 657
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/94 (42%), Positives = 56/94 (59%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y A + S ++ +N+ + VTWGVFP V Q TI++ SFK W+DEAF IWS WA
Sbjct: 555 SYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWA 613
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + P+ LL V Y LVS+V ++ D
Sbjct: 614 KLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647
[141][TOP]
>UniRef100_B3LL40 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LL40_YEAS1
Length = 657
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/94 (42%), Positives = 56/94 (59%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y A + S ++ +N+ + VTWGVFP V Q TI++ SFK W+DEAF IWS WA
Sbjct: 555 SYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWA 613
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + P+ LL V Y LVS+V ++ D
Sbjct: 614 KLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647
[142][TOP]
>UniRef100_P46151 Methylenetetrahydrofolate reductase 1 n=1 Tax=Saccharomyces
cerevisiae RepID=MTHR1_YEAST
Length = 657
Score = 80.1 bits (196), Expect = 7e-14
Identities = 40/94 (42%), Positives = 56/94 (59%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y A + S ++ +N+ + VTWGVFP V Q TI++ SFK W+DEAF IWS WA
Sbjct: 555 SYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWS-EWA 613
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + P+ LL V Y LVS+V ++ D
Sbjct: 614 KLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647
[143][TOP]
>UniRef100_Q75EA7 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q75EA7_ASHGO
Length = 603
Score = 79.7 bits (195), Expect = 9e-14
Identities = 41/97 (42%), Positives = 61/97 (62%), Gaps = 3/97 (3%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNI-GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWS 296
P++TY AV+ +N SN ++ NAVTWG+FP ++V+QPTIV+ ASF WKDE + I
Sbjct: 494 PTLTYFAVDADDNLASNHPDDTQANAVTWGIFPGREVLQPTIVEKASFLAWKDEFYRILD 553
Query: 295 RSWANLYPEDD--PSRKLLEEVKSSYYLVSLVDTNYI 191
W + E+ S LL + S Y LV++VD +++
Sbjct: 554 -DWRLSFDENGAADSAALLAHLTSDYALVNIVDNDFV 589
[144][TOP]
>UniRef100_Q752W6 Methylenetetrahydrofolate reductase n=1 Tax=Eremothecium gossypii
RepID=Q752W6_ASHGO
Length = 635
Score = 79.7 bits (195), Expect = 9e-14
Identities = 36/94 (38%), Positives = 56/94 (59%)
Frame = -1
Query: 463 TYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWA 284
+Y + + ++ SN+ + VTWGVFP Q++Q TI++ SFK W+DEAF IW SW+
Sbjct: 535 SYYFGDSAGSFASNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIW-LSWS 593
Query: 283 NLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
L+P + P L + Y LVS+V ++ + D
Sbjct: 594 KLFPRNSPHNAFLRGIHRDYCLVSIVHHDFSSVD 627
[145][TOP]
>UniRef100_C9S8T9 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S8T9_9PEZI
Length = 670
Score = 79.7 bits (195), Expect = 9e-14
Identities = 32/74 (43%), Positives = 50/74 (67%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
+ NAVTWGVFP K++I PTI++ SF+ W +EAF+IW W+ +Y S K L+ VK
Sbjct: 587 ASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFKIWG-EWSRVYGRGHESEKFLKTVK 645
Query: 232 SSYYLVSLVDTNYI 191
Y+LV+++ +++
Sbjct: 646 EEYWLVNIIHHDFV 659
[146][TOP]
>UniRef100_A5DZ35 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DZ35_LODEL
Length = 622
Score = 79.7 bits (195), Expect = 9e-14
Identities = 35/70 (50%), Positives = 48/70 (68%)
Frame = -1
Query: 403 NAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSY 224
NAVTWGVFP K+V+QPT++D SFK W +EAF +W WA Y ++ + +LL V+ +Y
Sbjct: 542 NAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLW-LEWARCYKKNSKTYELLNSVRDNY 600
Query: 223 YLVSLVDTNY 194
LVSL+ Y
Sbjct: 601 VLVSLIHHEY 610
[147][TOP]
>UniRef100_UPI00003BE162 hypothetical protein DEHA0F09867g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE162
Length = 642
Score = 79.3 bits (194), Expect = 1e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIG-----ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFE 305
+ITY + SN+ + NA+TWGVFP K+V+QPTI+D SFK W +EAF
Sbjct: 533 TITYYCGDAEGRLTSNLNIDQEHYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFI 592
Query: 304 IWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
+W WA Y + + +LL + YYLVSL+ ++
Sbjct: 593 LW-LEWARCYKKTSKTYELLNSIYKDYYLVSLISHDF 628
[148][TOP]
>UniRef100_Q0CE17 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus terreus
NIH2624 RepID=Q0CE17_ASPTN
Length = 696
Score = 79.3 bits (194), Expect = 1e-13
Identities = 32/73 (43%), Positives = 49/73 (67%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VNAVTWGVF K+++ PTI++ SF+ W DEA+ IW W +YP P+ + LEE K
Sbjct: 600 NNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPRGSPTERFLEETK 658
Query: 232 SSYYLVSLVDTNY 194
+ +LV +V ++
Sbjct: 659 NDVWLVCVVGQDF 671
[149][TOP]
>UniRef100_C4R2L4 Methylenetetrahydrofolate reductase n=1 Tax=Pichia pastoris GS115
RepID=C4R2L4_PICPG
Length = 596
Score = 78.6 bits (192), Expect = 2e-13
Identities = 33/72 (45%), Positives = 50/72 (69%)
Frame = -1
Query: 403 NAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSSY 224
N+VTWG FP K+++Q TI+ SF+ W +EAF IW R W LYP++ S LL + +++
Sbjct: 515 NSVTWGCFPDKEIVQTTIIGEESFQAWNEEAFNIW-REWQKLYPKNTASYNLLGSIINNF 573
Query: 223 YLVSLVDTNYIN 188
YLV+L++ +Y N
Sbjct: 574 YLVTLINHDYAN 585
[150][TOP]
>UniRef100_A5DXM5 Methylenetetrahydrofolate reductase n=1 Tax=Lodderomyces
elongisporus RepID=A5DXM5_LODEL
Length = 618
Score = 78.2 bits (191), Expect = 3e-13
Identities = 39/106 (36%), Positives = 63/106 (59%), Gaps = 11/106 (10%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR-- 293
I+Y AV+ N +N + D+NAVTWGVFP ++++QPTIV+ SF WKDE + ++S
Sbjct: 497 ISYYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFSEWR 556
Query: 292 -----SWANLYPEDDPS----RKLLEEVKSSYYLVSLVDTNYINGD 182
+ A++ ED + KL+ E Y L +LV+ ++I+ +
Sbjct: 557 KVLTSNLADVKDEDKKNLHKFEKLMTEFSEDYVLCNLVNNDFIDSN 602
[151][TOP]
>UniRef100_UPI000151BABB hypothetical protein PGUG_04648 n=1 Tax=Pichia guilliermondii ATCC
6260 RepID=UPI000151BABB
Length = 355
Score = 77.8 bits (190), Expect = 4e-13
Identities = 40/114 (35%), Positives = 66/114 (57%), Gaps = 14/114 (12%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A +K+ +N E D+NAVTWGVFP ++++QPTIV+ SF WKDE + + + W
Sbjct: 235 LTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EW 293
Query: 286 ANLY----PEDDPSRK--------LLEEVKSSYYLVSLVDTNYINGD--IFSVF 167
++Y D+ +K L E + L ++V+ N+++ D +FS+F
Sbjct: 294 GSVYDSHITSDETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDLVLFSIF 347
[152][TOP]
>UniRef100_C6HED8 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
H143 RepID=C6HED8_AJECH
Length = 713
Score = 77.8 bits (190), Expect = 4e-13
Identities = 31/75 (41%), Positives = 48/75 (64%)
Frame = -1
Query: 418 GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
G + V AVTWGVF K+++ PTI++ SF+ W DEAF IW W ++P P+ +LL++
Sbjct: 606 GNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPTERLLDQ 664
Query: 238 VKSSYYLVSLVDTNY 194
+K+ +L+ V Y
Sbjct: 665 LKNDVWLICCVGQKY 679
[153][TOP]
>UniRef100_C5M548 Methylenetetrahydrofolate reductase n=1 Tax=Candida tropicalis
MYA-3404 RepID=C5M548_CANTT
Length = 633
Score = 77.8 bits (190), Expect = 4e-13
Identities = 40/97 (41%), Positives = 61/97 (62%), Gaps = 5/97 (5%)
Frame = -1
Query: 481 KAIPSITYMAVNKSENWVSNIGES-DV----NAVTWGVFPAKQVIQPTIVDPASFKVWKD 317
+A SITY A +K+ + + D+ NAVTWGVFP+K+V+QPT++D SFK W +
Sbjct: 521 EASDSITYYAADKTNKIEAKVPAGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNE 580
Query: 316 EAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLV 206
E+F +W W+ Y ++ S +LL +V +Y LV L+
Sbjct: 581 ESFLLW-LEWSRCYKKNSKSFELLNKVYENYVLVCLI 616
[154][TOP]
>UniRef100_C0NTN2 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
G186AR RepID=C0NTN2_AJECG
Length = 713
Score = 77.8 bits (190), Expect = 4e-13
Identities = 31/75 (41%), Positives = 48/75 (64%)
Frame = -1
Query: 418 GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
G + V AVTWGVF K+++ PTI++ SF+ W DEAF IW W ++P P+ +LL++
Sbjct: 606 GNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPTERLLDQ 664
Query: 238 VKSSYYLVSLVDTNY 194
+K+ +L+ V Y
Sbjct: 665 LKNDVWLICCVGQKY 679
[155][TOP]
>UniRef100_A6QT35 Methylenetetrahydrofolate reductase n=1 Tax=Ajellomyces capsulatus
NAm1 RepID=A6QT35_AJECN
Length = 712
Score = 77.8 bits (190), Expect = 4e-13
Identities = 31/75 (41%), Positives = 48/75 (64%)
Frame = -1
Query: 418 GESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEE 239
G + V AVTWGVF K+++ PTI++ SF+ W DEAF IW W ++P P+ +LL++
Sbjct: 605 GNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIFPRGSPTERLLDQ 663
Query: 238 VKSSYYLVSLVDTNY 194
+K+ +L+ V Y
Sbjct: 664 LKNDVWLICCVGQKY 678
[156][TOP]
>UniRef100_A5DMZ7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia guilliermondii
RepID=A5DMZ7_PICGU
Length = 355
Score = 77.8 bits (190), Expect = 4e-13
Identities = 40/114 (35%), Positives = 66/114 (57%), Gaps = 14/114 (12%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY A +K+ +N E D+NAVTWGVFP ++++QPTIV+ SF WKDE + + + W
Sbjct: 235 LTYYAADKNGELNTNTKEDDINAVTWGVFPGEEILQPTIVEKTSFFAWKDEVYRLLA-EW 293
Query: 286 ANLY----PEDDPSRK--------LLEEVKSSYYLVSLVDTNYINGD--IFSVF 167
++Y D+ +K L E + L ++V+ N+++ D +FS+F
Sbjct: 294 GSVYDSHITSDETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDSVLFSIF 347
[157][TOP]
>UniRef100_B9WDQ7 Methylenetetrahydrofolate reductase n=1 Tax=Candida dubliniensis
CD36 RepID=B9WDQ7_CANDC
Length = 614
Score = 77.4 bits (189), Expect = 5e-13
Identities = 36/103 (34%), Positives = 66/103 (64%), Gaps = 8/103 (7%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI---WS 296
I+Y AV+K N +N + D+NAVTWGVFP ++++QPTIV+ SF WKDE + + W+
Sbjct: 496 ISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFTEWA 555
Query: 295 RSWANLYPEDDPSR-----KLLEEVKSSYYLVSLVDTNYINGD 182
+ ++ E D ++ +L+++ + L +LV+ ++++G+
Sbjct: 556 KIASSNLVEADQTQVNEFVRLMKKFGDEFVLCNLVNNDFVDGN 598
[158][TOP]
>UniRef100_A8QAM7 Methylenetetrahydrofolate reductase n=1 Tax=Malassezia globosa CBS
7966 RepID=A8QAM7_MALGO
Length = 589
Score = 77.4 bits (189), Expect = 5e-13
Identities = 34/78 (43%), Positives = 51/78 (65%)
Frame = -1
Query: 427 SNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKL 248
+N+ + +N VTWGVFP +V Q TI++ ASF+ W+DEAF IW R W L+P + +R L
Sbjct: 499 TNLTTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAIW-REWELLFPPNSATRSL 557
Query: 247 LEEVKSSYYLVSLVDTNY 194
L + +LV++V +Y
Sbjct: 558 LRRIHDERWLVTVVHHDY 575
[159][TOP]
>UniRef100_Q5AEI0 Methylenetetrahydrofolate reductase n=1 Tax=Candida albicans
RepID=Q5AEI0_CANAL
Length = 614
Score = 77.0 bits (188), Expect = 6e-13
Identities = 36/104 (34%), Positives = 64/104 (61%), Gaps = 9/104 (8%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
I+Y AV+K N +N + D+NAVTWGVFP ++++QPTIV+ SF WKDE + +++ W
Sbjct: 496 ISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EW 554
Query: 286 ANLYPED---------DPSRKLLEEVKSSYYLVSLVDTNYINGD 182
A + + D +L+++ + L +LV+ ++++G+
Sbjct: 555 AKIASSNLVEANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGN 598
[160][TOP]
>UniRef100_B2WHR5 Methylenetetrahydrofolate reductase n=1 Tax=Pyrenophora
tritici-repentis Pt-1C-BFP RepID=B2WHR5_PYRTR
Length = 653
Score = 77.0 bits (188), Expect = 6e-13
Identities = 37/102 (36%), Positives = 61/102 (59%)
Frame = -1
Query: 487 KSKAIPSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAF 308
K +A +T+ A N + + ++ E VN VTWG F K+++ PTI++ SF+ W DEAF
Sbjct: 546 KLQAHDQVTWFAGNAAGAFEAS-QEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAF 604
Query: 307 EIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGD 182
IW + W +YP S LL E+ +LV+++ +++NG+
Sbjct: 605 SIW-KEWQRIYPPRSGSSVLLGELSKDVWLVNVIWGDFVNGE 645
[161][TOP]
>UniRef100_C9S7I3 Methylenetetrahydrofolate reductase n=1 Tax=Verticillium albo-atrum
VaMs.102 RepID=C9S7I3_9PEZI
Length = 312
Score = 76.6 bits (187), Expect = 8e-13
Identities = 36/72 (50%), Positives = 45/72 (62%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P +TY AV KS N N NAVTWGVFP K+++QPTIV+ SF WKDEAF +
Sbjct: 188 PDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRL-GL 246
Query: 292 SWANLYPEDDPS 257
WA+ + + PS
Sbjct: 247 DWAHCFEQSSPS 258
[162][TOP]
>UniRef100_C8V780 Methylenetetrahydrofolate reductase (EC 1.5.1.20)
[Source:UniProtKB/TrEMBL;Acc:Q5AU15] n=2 Tax=Emericella
nidulans RepID=C8V780_EMENI
Length = 684
Score = 76.6 bits (187), Expect = 8e-13
Identities = 31/73 (42%), Positives = 49/73 (67%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VNAVTWGVF K+++ PTI++ SF+ W DEA+ IW W +YP+ + K LE+ K
Sbjct: 588 NNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKSSATEKFLEKTK 646
Query: 232 SSYYLVSLVDTNY 194
+ +LV +V ++
Sbjct: 647 NDVWLVCVVGQDF 659
[163][TOP]
>UniRef100_A2QUJ5 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus niger CBS
513.88 RepID=A2QUJ5_ASPNC
Length = 699
Score = 76.3 bits (186), Expect = 1e-12
Identities = 30/77 (38%), Positives = 51/77 (66%)
Frame = -1
Query: 424 NIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLL 245
+I ++VNAVTWGVF K+++ PTI++ SF+ W DEA+ IW W +YP++ + + L
Sbjct: 598 DINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD-EWRRIYPKNSATERFL 656
Query: 244 EEVKSSYYLVSLVDTNY 194
++ K+ +LV +V +
Sbjct: 657 DDTKNDVWLVCVVGQEF 673
[164][TOP]
>UniRef100_UPI00003BE4A8 hypothetical protein DEHA0G01551g n=1 Tax=Debaryomyces hansenii
CBS767 RepID=UPI00003BE4A8
Length = 617
Score = 75.9 bits (185), Expect = 1e-12
Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 12/105 (11%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY AV++ SN + D+NAVTWGVFP ++++QPTIV+ SF WKDE + + + W
Sbjct: 496 LTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EW 554
Query: 286 ANLYPED------------DPSRKLLEEVKSSYYLVSLVDTNYIN 188
++ D D KL+ Y L ++V+ N+I+
Sbjct: 555 IKIFQSDFVKDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFID 599
[165][TOP]
>UniRef100_Q2HBA5 Methylenetetrahydrofolate reductase n=1 Tax=Chaetomium globosum
RepID=Q2HBA5_CHAGB
Length = 643
Score = 75.9 bits (185), Expect = 1e-12
Identities = 30/78 (38%), Positives = 50/78 (64%)
Frame = -1
Query: 415 ESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEV 236
E+ NAV+WGVFP K+++ PTI++ SF+ W +EAF IW W +Y + S + LE V
Sbjct: 565 EASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAFGIWG-EWVKIYEKGSESERFLERV 623
Query: 235 KSSYYLVSLVDTNYINGD 182
+ +LV+++ +++ D
Sbjct: 624 LADTWLVNIIHHDFLETD 641
[166][TOP]
>UniRef100_Q1DT03 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides immitis
RepID=Q1DT03_COCIM
Length = 711
Score = 75.9 bits (185), Expect = 1e-12
Identities = 32/71 (45%), Positives = 45/71 (63%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W +EAF IW W ++P P+ KLL VK
Sbjct: 612 VNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRRIFPRGSPTEKLLNRVKED 670
Query: 226 YYLVSLVDTNY 194
+LV ++ +
Sbjct: 671 TWLVCVIGQRF 681
[167][TOP]
>UniRef100_C5P4Q4 Methylenetetrahydrofolate reductase n=1 Tax=Coccidioides posadasii
C735 delta SOWgp RepID=C5P4Q4_COCP7
Length = 711
Score = 75.9 bits (185), Expect = 1e-12
Identities = 32/71 (45%), Positives = 45/71 (63%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W +EAF IW W ++P P+ KLL VK
Sbjct: 612 VNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRRIFPRGSPTEKLLNRVKED 670
Query: 226 YYLVSLVDTNY 194
+LV ++ +
Sbjct: 671 TWLVCVIGQRF 681
[168][TOP]
>UniRef100_B5RV11 Methylenetetrahydrofolate reductase n=1 Tax=Debaryomyces hansenii
RepID=B5RV11_DEBHA
Length = 617
Score = 75.9 bits (185), Expect = 1e-12
Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 12/105 (11%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
+TY AV++ SN + D+NAVTWGVFP ++++QPTIV+ SF WKDE + + + W
Sbjct: 496 LTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLIT-EW 554
Query: 286 ANLYPED------------DPSRKLLEEVKSSYYLVSLVDTNYIN 188
++ D D KL+ Y L ++V+ N+I+
Sbjct: 555 IKIFQSDFVKDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFID 599
[169][TOP]
>UniRef100_A7TTE9 Methylenetetrahydrofolate reductase n=1 Tax=Vanderwaltozyma
polyspora DSM 70294 RepID=A7TTE9_VANPO
Length = 612
Score = 75.5 bits (184), Expect = 2e-12
Identities = 40/111 (36%), Positives = 63/111 (56%), Gaps = 15/111 (13%)
Frame = -1
Query: 469 SITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI--- 302
S+TY+A + W SN + + AVTWGVFP ++V+QPTIV+ SF W+DE + I
Sbjct: 492 SLTYLAADSHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLAWRDEFYRILQD 551
Query: 301 WSRSWANLYPEDD-----------PSRKLLEEVKSSYYLVSLVDTNYINGD 182
W + + P+ D PS KL++ + Y LV+L+D ++++ D
Sbjct: 552 WRDIFVHASPDGDQCDNGSAQRENPSAKLMQLMIDDYVLVNLIDNDFVSVD 602
[170][TOP]
>UniRef100_Q6FU20 Methylenetetrahydrofolate reductase n=1 Tax=Candida glabrata
RepID=Q6FU20_CANGA
Length = 600
Score = 75.1 bits (183), Expect = 2e-12
Identities = 40/104 (38%), Positives = 66/104 (63%), Gaps = 5/104 (4%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY AV+ +N SN + S NAVTWG+FP ++V+QPTIV+ SF WK+E + I
Sbjct: 494 LTYFAVDNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFLAWKEEFYRI-LEE 552
Query: 289 WANLYPEDD--PSRKLLEEVKSSYYLVSLVDTNYING--DIFSV 170
W + E++ S + ++ + +Y LV++VD +YI+ +I++V
Sbjct: 553 WKWNFQENNELKSAEFIQHIIDNYMLVNIVDNDYISSTDEIYNV 596
[171][TOP]
>UniRef100_C4Y415 Methylenetetrahydrofolate reductase n=1 Tax=Clavispora lusitaniae
ATCC 42720 RepID=C4Y415_CLAL4
Length = 614
Score = 75.1 bits (183), Expect = 2e-12
Identities = 43/106 (40%), Positives = 63/106 (59%), Gaps = 8/106 (7%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI---W- 299
ITY AV+KS N +N D+NAVTWGVFP ++++QPTIV+ SF WKDE + + W
Sbjct: 495 ITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWI 554
Query: 298 ----SRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDIFS 173
S++ ++ PE D K + +KS + + V N++N D S
Sbjct: 555 TIFHSKAITDIVPE-DKINKFDDLIKS--FGENFVLCNFVNNDFTS 597
[172][TOP]
>UniRef100_C8Z8C5 Met13p n=1 Tax=Saccharomyces cerevisiae EC1118 RepID=C8Z8C5_YEAST
Length = 600
Score = 74.7 bits (182), Expect = 3e-12
Identities = 37/97 (38%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY A++ + +SN + S NAVTWG+FP ++++QPTIV+ SF WK+E + I +
Sbjct: 494 LTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEW 553
Query: 289 WANLYPEDDP-SRKLLEEVKSSYYLVSLVDTNYINGD 182
N+ D P S + ++ + Y LV++VD +YI+ D
Sbjct: 554 KLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 590
[173][TOP]
>UniRef100_C5FI42 Methylenetetrahydrofolate reductase n=1 Tax=Microsporum canis CBS
113480 RepID=C5FI42_NANOT
Length = 715
Score = 74.7 bits (182), Expect = 3e-12
Identities = 31/79 (39%), Positives = 49/79 (62%)
Frame = -1
Query: 430 VSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRK 251
++++ VNAVTWGVF K+++ PTI++ SF+ W +EAF IW W ++P S K
Sbjct: 564 LTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIW-EEWRRIFPRGSASEK 622
Query: 250 LLEEVKSSYYLVSLVDTNY 194
L+ +VK +LV +V +
Sbjct: 623 LIRDVKDDVWLVCVVGQRF 641
[174][TOP]
>UniRef100_B5VIK4 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae AWRI1631 RepID=B5VIK4_YEAS6
Length = 411
Score = 74.7 bits (182), Expect = 3e-12
Identities = 37/97 (38%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY A++ + +SN + S NAVTWG+FP ++++QPTIV+ SF WK+E + I +
Sbjct: 305 LTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEW 364
Query: 289 WANLYPEDDP-SRKLLEEVKSSYYLVSLVDTNYINGD 182
N+ D P S + ++ + Y LV++VD +YI+ D
Sbjct: 365 KLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 401
[175][TOP]
>UniRef100_B3LHI5 Methylenetetrahydrofolate reductase n=1 Tax=Saccharomyces
cerevisiae RM11-1a RepID=B3LHI5_YEAS1
Length = 600
Score = 74.7 bits (182), Expect = 3e-12
Identities = 37/97 (38%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY A++ + +SN + S NAVTWG+FP ++++QPTIV+ SF WK+E + I +
Sbjct: 494 LTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEW 553
Query: 289 WANLYPEDDP-SRKLLEEVKSSYYLVSLVDTNYINGD 182
N+ D P S + ++ + Y LV++VD +YI+ D
Sbjct: 554 KLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 590
[176][TOP]
>UniRef100_P53128 Methylenetetrahydrofolate reductase 2 n=3 Tax=Saccharomyces
cerevisiae RepID=MTHR2_YEAST
Length = 600
Score = 74.7 bits (182), Expect = 3e-12
Identities = 37/97 (38%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY A++ + +SN + S NAVTWG+FP ++++QPTIV+ SF WK+E + I +
Sbjct: 494 LTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEW 553
Query: 289 WANLYPEDDP-SRKLLEEVKSSYYLVSLVDTNYINGD 182
N+ D P S + ++ + Y LV++VD +YI+ D
Sbjct: 554 KLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 590
[177][TOP]
>UniRef100_Q2UA39 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus oryzae
RepID=Q2UA39_ASPOR
Length = 690
Score = 74.3 bits (181), Expect = 4e-12
Identities = 29/73 (39%), Positives = 47/73 (64%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VN VTWGVF K+++ PTI++ SF+ W DEAF IW W +YP + + + L ++K
Sbjct: 592 NNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNSATERFLNDIK 650
Query: 232 SSYYLVSLVDTNY 194
+LV +V ++
Sbjct: 651 DDVWLVCVVGQDF 663
[178][TOP]
>UniRef100_B8NQE8 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus flavus
NRRL3357 RepID=B8NQE8_ASPFN
Length = 738
Score = 74.3 bits (181), Expect = 4e-12
Identities = 29/73 (39%), Positives = 47/73 (64%)
Frame = -1
Query: 412 SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVK 233
++VN VTWGVF K+++ PTI++ SF+ W DEAF IW W +YP + + + L ++K
Sbjct: 640 NNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD-EWRRIYPRNSATERFLNDIK 698
Query: 232 SSYYLVSLVDTNY 194
+LV +V ++
Sbjct: 699 DDVWLVCVVGQDF 711
[179][TOP]
>UniRef100_A3LUC7 Methylenetetrahydrofolate reductase n=1 Tax=Pichia stipitis
RepID=A3LUC7_PICST
Length = 613
Score = 74.3 bits (181), Expect = 4e-12
Identities = 36/102 (35%), Positives = 63/102 (61%), Gaps = 9/102 (8%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSW 287
I+Y AV+K+ N +N + D+NAVTWGVFP ++++QPTIV+ SF WKDE + +++ W
Sbjct: 496 ISYYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSFLAWKDEVYRLFT-EW 554
Query: 286 ANLYPED--DPSR-------KLLEEVKSSYYLVSLVDTNYIN 188
N+ + D + L+ +++ L +LV+ ++I+
Sbjct: 555 TNILQSNLVDADKDKISGFVDLITNFSNNFVLCNLVNNDFID 596
[180][TOP]
>UniRef100_Q6CKM1 Methylenetetrahydrofolate reductase n=1 Tax=Kluyveromyces lactis
RepID=Q6CKM1_KLULA
Length = 604
Score = 73.2 bits (178), Expect = 9e-12
Identities = 38/96 (39%), Positives = 59/96 (61%), Gaps = 3/96 (3%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGE-SDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRS 290
+TY A++ +N +N E S NAVTWGVFP +++QPTIV+ ASF WK+E F I +
Sbjct: 497 LTYFAIDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKASFLAWKEEFFTI-LKE 555
Query: 289 WANLYPED--DPSRKLLEEVKSSYYLVSLVDTNYIN 188
W + E S L+ + +Y L+++VD ++I+
Sbjct: 556 WKLTFVEHKATESVNLVNHIIDNYVLINVVDNDFIS 591
[181][TOP]
>UniRef100_C1H0K0 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb01 RepID=C1H0K0_PARBA
Length = 713
Score = 73.2 bits (178), Expect = 9e-12
Identities = 30/71 (42%), Positives = 46/71 (64%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W DEAF IW W ++ P+ +LL+++K
Sbjct: 609 VNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWD-EWRRIFRRGSPTEQLLDQLKKD 667
Query: 226 YYLVSLVDTNY 194
+L+ +V +
Sbjct: 668 AWLICVVGQKF 678
[182][TOP]
>UniRef100_C5E412 Methylenetetrahydrofolate reductase n=1 Tax=Zygosaccharomyces
rouxii CBS 732 RepID=C5E412_ZYGRC
Length = 599
Score = 72.8 bits (177), Expect = 1e-11
Identities = 39/97 (40%), Positives = 59/97 (60%), Gaps = 4/97 (4%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESD-VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEI---W 299
+TY AV+ + N +N + NAVTWG+FP ++V+QPTIV+ SF WK E + I W
Sbjct: 493 LTYFAVDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLAWKQEFYHICEEW 552
Query: 298 SRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYIN 188
++ N D S KLL+ + Y LV++VD ++I+
Sbjct: 553 KLNFIN--HRCDQSVKLLQHLIDDYVLVNIVDNDFIS 587
[183][TOP]
>UniRef100_C4JM22 Methylenetetrahydrofolate reductase n=1 Tax=Uncinocarpus reesii
1704 RepID=C4JM22_UNCRE
Length = 709
Score = 72.4 bits (176), Expect = 1e-11
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W +EAF IW W ++ P+ KLL + K
Sbjct: 610 VNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWD-EWRRIFARGSPTEKLLAQTKED 668
Query: 226 YYLVSLVDTNY 194
+LV +V +
Sbjct: 669 VWLVCVVGQRF 679
[184][TOP]
>UniRef100_B6HK87 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium chrysogenum
Wisconsin 54-1255 RepID=B6HK87_PENCW
Length = 691
Score = 72.4 bits (176), Expect = 1e-11
Identities = 30/71 (42%), Positives = 44/71 (61%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K+++ PTI++ SF+ W +EAF IW W +YP P+ L+ K+
Sbjct: 595 VNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWD-EWRRIYPRGSPTETYLDTTKND 653
Query: 226 YYLVSLVDTNY 194
+LV +V +
Sbjct: 654 SWLVCVVGQQF 664
[185][TOP]
>UniRef100_A1C4Z1 Methylenetetrahydrofolate reductase n=1 Tax=Aspergillus clavatus
RepID=A1C4Z1_ASPCL
Length = 690
Score = 72.4 bits (176), Expect = 1e-11
Identities = 28/72 (38%), Positives = 47/72 (65%)
Frame = -1
Query: 409 DVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKS 230
+VNAVTWGVF K+++ PTI++ SF+ W +EA+ IW W +YP + + ++E K+
Sbjct: 594 NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIW-EEWRRIYPRGSATERFIDETKN 652
Query: 229 SYYLVSLVDTNY 194
+LV +V ++
Sbjct: 653 DVWLVCVVGQDF 664
[186][TOP]
>UniRef100_B8MDD4 Methylenetetrahydrofolate reductase n=1 Tax=Talaromyces stipitatus
ATCC 10500 RepID=B8MDD4_TALSN
Length = 713
Score = 71.2 bits (173), Expect = 3e-11
Identities = 34/98 (34%), Positives = 52/98 (53%)
Frame = -1
Query: 472 PSITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSR 293
P T AV ++ I ES AVTWG F +++ PTI++ SF+ W +EAF IW
Sbjct: 596 PEDTSSAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWD- 654
Query: 292 SWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNYINGDI 179
W +YP + +LL E K+ +L+ ++ Y G +
Sbjct: 655 EWRRIYPRGSATERLLNETKNDVWLLCVIGHRYGAGTV 692
[187][TOP]
>UniRef100_C1GJU2 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb18 RepID=C1GJU2_PARBD
Length = 712
Score = 70.5 bits (171), Expect = 6e-11
Identities = 29/71 (40%), Positives = 45/71 (63%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W EAF IW W ++ P+ +LL+++K
Sbjct: 609 VNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRRIFRRGSPTEQLLDQLKKD 667
Query: 226 YYLVSLVDTNY 194
+L+ +V +
Sbjct: 668 AWLICVVGQKF 678
[188][TOP]
>UniRef100_C0S8C4 Methylenetetrahydrofolate reductase n=1 Tax=Paracoccidioides
brasiliensis Pb03 RepID=C0S8C4_PARBP
Length = 712
Score = 70.5 bits (171), Expect = 6e-11
Identities = 29/71 (40%), Positives = 45/71 (63%)
Frame = -1
Query: 406 VNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLEEVKSS 227
VNAVTWGVF K++I PTI++ SF+ W EAF IW W ++ P+ +LL+++K
Sbjct: 609 VNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWD-EWRRIFRRGSPTEQLLDQLKKD 667
Query: 226 YYLVSLVDTNY 194
+L+ +V +
Sbjct: 668 AWLICVVGQKF 678
[189][TOP]
>UniRef100_B6K4Z7 Methylenetetrahydrofolate reductase n=1 Tax=Schizosaccharomyces
japonicus yFS275 RepID=B6K4Z7_SCHJY
Length = 605
Score = 68.2 bits (165), Expect = 3e-10
Identities = 35/76 (46%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
Frame = -1
Query: 418 GESDV-NAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
GE DV +AVTWGVFP +VIQPT+V+ ASF WKDEA+ + SWA + KLL
Sbjct: 505 GELDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDEAYSL-GLSWAKAHSSTSAPFKLLT 563
Query: 241 EVKSSYYLVSLVDTNY 194
+ + L +VD ++
Sbjct: 564 NIVKEWKLCVIVDNDF 579
[190][TOP]
>UniRef100_B6QFH8 Methylenetetrahydrofolate reductase n=1 Tax=Penicillium marneffei
ATCC 18224 RepID=B6QFH8_PENMQ
Length = 710
Score = 67.0 bits (162), Expect = 6e-10
Identities = 28/76 (36%), Positives = 44/76 (57%)
Frame = -1
Query: 421 IGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWKDEAFEIWSRSWANLYPEDDPSRKLLE 242
+ ES AVTWG F +++ PTI++ SF+ W +EAF IW W +YP + +LL
Sbjct: 610 VRESKGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWD-EWRRIYPRGSATERLLN 668
Query: 241 EVKSSYYLVSLVDTNY 194
E K+ +L+ ++ Y
Sbjct: 669 ETKNDAWLLCVIGHRY 684
[191][TOP]
>UniRef100_Q59GJ6 Methylenetetrahydrofolate reductase (Fragment) n=1 Tax=Homo sapiens
RepID=Q59GJ6_HUMAN
Length = 672
Score = 58.9 bits (141), Expect = 2e-07
Identities = 24/49 (48%), Positives = 32/49 (65%)
Frame = -1
Query: 466 ITYMAVNKSENWVSNIGESDVNAVTWGVFPAKQVIQPTIVDPASFKVWK 320
+ Y VN ++N E NAVTWG+FP +++IQPT+VDP SF WK
Sbjct: 566 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWK 614
[192][TOP]
>UniRef100_UPI00006A0177 Methylenetetrahydrofolate reductase (EC 1.5.1.20). n=1 Tax=Xenopus
(Silurana) tropicalis RepID=UPI00006A0177
Length = 641
Score = 53.1 bits (126), Expect = 9e-06
Identities = 20/42 (47%), Positives = 30/42 (71%)
Frame = -1
Query: 319 DEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDTNY 194
DEAF +W WA LY E+ PSR +++ + +YYLV+LVD ++
Sbjct: 577 DEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDF 618