hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm06042/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1113  ( 1071 res)   mpm06042

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
BBC      B-Box C-terminal domain                        163.6      2e-44   1
BROMO    bromo domain                                   132.1      6e-35   1
BBOX     B-Box-type zinc finger, protein interaction     89.7    3.4e-22   2
PHD      PHD zinc finger                                 49.3    4.9e-10   2
RING     Ring finger                                     30.3    0.00026   3

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RING       1/3      87   146 ..     1    23 []    42.6  5.3e-08
PHD        1/2      86   147 ..     1    39 []     3.3       17
BBOX       1/2     174   221 ..     1    51 []    47.3    2e-09
RING       2/3     179   241 ..     1    23 []     6.7      3.4
BBOX       2/2     233   274 ..     1    51 []    50.4  2.3e-10
BBC        1/1     281   407 ..     1   132 []   163.6    2e-44
RING       3/3     851   892 ..     1    23 []    -4.7       73
PHD        2/2     850   893 ..     1    39 []    52.1  7.4e-11
BROMO      1/1     920  1026 ..     1   118 []   132.1    6e-35

Alignments of top-scoring domains:
RING: domain 1 of 3, from 87 to 146: score 42.6, E = 5.3e-08
                   *->CpICle.........pvvlpCgH.FCr.Ci.................
                      C++C ++ +++++ +p++lpC H+FC +C+++++++ + + ++++++
   mKIAA1113    87    CAVCQQslqsrreaePKLLPCLHsFCLrCLpeperqlsvpipggsng 133  

                   .........CPlC<-*
                   + ++ +  +CP+C   
   mKIAA1113   134 dvqqvgvirCPVC    146  

PHD: domain 1 of 2, from 86 to 147: score 3.3, E = 17
                   *->yC.vCgk.........g.llqCdkgCdrwyHv.Clgpple.......
                      +C vC+++  ++++ + +ll C        H  Cl+  +e++++ + 
   mKIAA1113    86    TCaVCQQslqsrreaePkLLPCL-------HSfCLRCLPEperqlsv 125  

                   ..........epdg.wyCprCk<-*
                   + +++++++  + g  +Cp C+   
   mKIAA1113   126 pipggsngdvQQVGvIRCPVCR    147  

BBOX: domain 1 of 2, from 174 to 221: score 47.3, E = 2e-09
                   *->eraplCeeHgdeepaeffCveedgallCrdCdeageHqanklfrgHr
                      +++++C++++d++ a+ fC +e+g++lC++C ea  Hq++k++++H 
   mKIAA1113   174    KSEQVCTSCEDNASAVGFC-VECGEWLCKTCIEA--HQRVKFTKDHL 217  

                   vvll<-*
                   ++     
   mKIAA1113   218 IRKK    221  

RING: domain 2 of 3, from 179 to 241: score 6.7, E = 3.4
                   *->CpICle.....pvvlpCgH.FCr.Ci.....................
                      C+ C ++ +   ++ +Cg   C++Ci+ +++ + ++++  +++++ +
   mKIAA1113   179    CTSCEDnasavGFCVECGEwLCKtCIeahqrvkftkdhlirkkedvs 225  

                   ............CPlC<-*
                   ++ +++++++  CP+    
   mKIAA1113   226 esvgtsgqrpvfCPVH    241  

BBOX: domain 2 of 2, from 233 to 274: score 50.4, E = 2.3e-10
                   *->eraplCeeHgdeepaeffCveedgallCrdCdeageHqanklfrgHr
                      +r++ C++H+  e +++fC e+++ l CrdC +  eH      + Hr
   mKIAA1113   233    QRPVFCPVHK-QEQLKLFC-ETCDRLTCRDCQLL-EH------KEHR 270  

                   vvll<-*
                   +++l   
   mKIAA1113   271 YQFL    274  

BBC: domain 1 of 1, from 281 to 407: score 163.6, E = 2e-44
                   *->qreaLeelleklrkkaeelekalkqldsiiqevegGqvdenaeevea
                      q+ a+e ll+kl +k+++ ++a+ q++++i+ev+     e+ ++ve+
   mKIAA1113   281    QKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVN-----ETNKRVEQ 322  

                   eikaafdeLrnaLnerkkqLledLeevkenklkkLeqQlesltqkqekle
                   eik+a+++L+n++n+++k Ll++Le+v++++++kL qQ+ ++t+++++++
   mKIAA1113   323 EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVK 372  

                   hainfaeeaLnsgdptelLlskkliierlqellkq<-*
                   h++nf+++a+ sg++t+lL+sk+li+++l++ lk+   
   mKIAA1113   373 HVMNFTNWAIASGSSTALLYSKRLITFQLRHILKA    407  

RING: domain 3 of 3, from 851 to 892: score -4.7, E = 73
                   *->CpICle....pvvlpCgH.FCr.Ci.............CPlC<-*
                      C++C ++++ +++ +C   F+ +C  ++  + +++++ C +C   
   mKIAA1113   851    CAVCQNggdlLCCEKCPKvFHLtCHvptllsfpsgdwiCTFC    892  

PHD: domain 2 of 2, from 850 to 893: score 52.1, E = 7.4e-11
                   *->yC.vCgk.g.llqCdkgCdrwyHv.Clgpple.epdg.wyCprCk<-
                      +C vC+ +g+ll+C+ +C++ +H++C+ p+l++ p+g+w+C  C+  
   mKIAA1113   850    WCaVCQNgGdLLCCE-KCPKVFHLtCHVPTLLsFPSGdWICTFCR   893  

                   *
                    
   mKIAA1113     -   -    

BROMO: domain 1 of 1, from 920 to 1026: score 132.1, E = 6e-35
                   *->spk.qkklqellkallekldshgvpssrGrplawpFlepvdkkeLgv
                      sp +q+k+++ll  l++++ s              F+epv+++   +
   mKIAA1113   920    SPVdQRKCERLLLYLYCHELSI------------EFQEPVPVS---I 951  

                   PDYydiIkkPMDLktIkkklengkY...ssleeFvaDfnLmfsNAktYNe
                   P+Yy+iIkkPMDL+t+kkkl++ + ++ + +++FvaD++L+f+N+  +Ne
   mKIAA1113   952 PNYYKIIKKPMDLSTVKKKLQKKHSqhyQIPDDFVADVRLIFKNCERFNE 1001 

                   pdsevykdAkkLeklfeeklkelpp<-*
                    dsev k++k    +fe+kl e++    
   mKIAA1113  1002 GDSEVAKAGKAVALYFEDKLSEIYS    1026 

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