hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/mpm/mpm06042/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1113 ( 1071 res) mpm06042 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Bromodomain Bromodomain 95.1 1.4e-24 1 zf-B_box B-box zinc finger 92.0 1.2e-23 2 PHD PHD-finger 54.5 2.3e-12 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- zf-B_box 1/2 176 221 .. 1 46 [] 44.0 3.4e-09 zf-B_box 2/2 235 274 .. 1 46 [] 55.7 1e-12 PHD 1/1 850 895 .. 1 51 [] 54.5 2.3e-12 Bromodomain 1/1 923 1012 .. 1 92 [] 95.1 1.4e-24 Alignments of top-scoring domains: zf-B_box: domain 1 of 2, from 176 to 221: score 44.0, E = 3.4e-09 *->ervCpeHg..ekaslfCedDqalLCvvCdesgeHsanklargHtvvp e+vC+++++++ a fC++++++LC +C e+ H+++k +++H ++ mKIAA1113 176 EQVCTSCEdnASAVGFCVECGEWLCKTCIEA--HQRVKFTKDHLIRK 220 l<-* mKIAA1113 221 K 221 zf-B_box: domain 2 of 2, from 235 to 274: score 55.7, E = 1e-12 *->ervCpeHg.ekaslfCedDqalLCvvCdesgeHsanklargHtvvpl +++Cp+H++e+++lfCe+++ l+C++C++ eH + H++++l mKIAA1113 235 PVFCPVHKqEQLKLFCETCDRLTCRDCQLL-EH------KEHRYQFL 274 <-* mKIAA1113 - - PHD: domain 1 of 1, from 850 to 895: score 54.5, E = 2.3e-12 *->yCsvCgkpdddaggdllqCDgCdrwfHlaClgppleeppegkWlCpe +C+vC+ ggdll+C++C++ fHl C+ p+l p+g+W+C mKIAA1113 850 WCAVCQN-----GGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTF 891 Ctpk<-* C+ mKIAA1113 892 CRDI 895 Bromodomain: domain 1 of 1, from 923 to 1012: score 95.1, E = 1.4e-24 *->lnklllkvlealdehgpralpflfpVlpsklelPDYYeiIkkPMDLk ++ + +l++l h+ ++ f +pV +s +P+YY+iIkkPMDL+ mKIAA1113 923 DQRKCERLLLYLYCHE-LSIEFQEPVPVS---IPNYYKIIKKPMDLS 965 TIkkklkngk...YissleeFvaDfnLmfsNAktYNepdsevykdAkk<- T+kkkl++ ++++Y + +++FvaD++L+f+N+ +Ne dsev k++k mKIAA1113 966 TVKKKLQKKHsqhY-QIPDDFVADVRLIFKNCERFNEGDSEVAKAGKA 1012 * mKIAA1113 - - //