hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm08346/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0667  ( 1243 res)   mpm08346

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HEAT     HEAT repeat                                    137.3    2.7e-37  12
HEAT_PBS PBS lyase HEAT-like repeat                      18.1        0.2   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
HEAT       1/12     51    87 ..     1    36 []    19.9    0.061
HEAT       2/12     89   125 ..     1    36 []     6.1       34
HEAT       3/12    178   214 ..     1    36 []    15.1      1.7
HEAT_PBS   1/2     199   225 ..     1    27 []     6.9       72
HEAT       4/12    261   297 ..     1    36 []    18.8     0.13
HEAT       5/12    439   474 ..     1    36 []    11.7      5.5
HEAT       6/12    523   559 ..     1    36 []    20.8    0.031
HEAT       7/12    571   609 ..     1    36 []     2.3  1.2e+02
HEAT       8/12    654   690 ..     1    36 []     8.8       14
HEAT       9/12    863   899 ..     1    36 []    20.0    0.055
HEAT_PBS   2/2     884   913 ..     1    27 []    13.2      6.2
HEAT      10/12    938   974 ..     1    36 []    16.3     0.74
HEAT      11/12   1013  1049 ..     1    36 []    13.3      3.3
HEAT      12/12   1073  1108 ..     1    36 []     1.9  1.3e+02

Alignments of top-scoring domains:
HEAT: domain 1 of 12, from 51 to 87: score 19.9, E = 0.061
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      e+   +++ +ll+ll+D + eV+  A+++Lg l+ ++   
   mKIAA0667    51    EdSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKV    87   

HEAT: domain 2 of 12, from 89 to 125: score 6.1, E = 34
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      e  +++++ +l+  ++++ +  R+ A   L ++++ l   
   mKIAA0667    89    EyQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSEL    125  

HEAT: domain 3 of 12, from 178 to 214: score 15.1, E = 1.7
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                       +++ +ll +ll  l++p   VR+ ++ aLg+la  +   
   mKIAA0667   178    GtFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAAC    214  

HEAT_PBS: domain 1 of 2, from 199 to 225: score 6.9, E = 72
                   *->vRraAaraLgalgdpeAipaLleaLed<-*
                      vR + + aLg l +  + ++ +e+ ++   
   mKIAA0667   199    VRKRTVVALGHLAAACSTDLFVELADH    225  

HEAT: domain 4 of 12, from 261 to 297: score 18.8, E = 0.13
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                        +ld+l+p++ + +n +d+e Re++++a+ a+++++   
   mKIAA0667   261    GaHLDRLVPMVEEFCNLDDDELRESCLQAFEAFLRKC    297  

HEAT: domain 5 of 12, from 439 to 474: score 11.7, E = 5.5
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      +++   ++ +l++ l+D + + R+ +++ + +la vl   
   mKIAA0667   439    AqVP-LVIKALQRQLKDRNVRTRQGCFNLFTELAGVL    474  

HEAT: domain 6 of 12, from 523 to 559: score 20.8, E = 0.031
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                       ++l++llp+++ +  Dp ++V + A+  L++l++ l   
   mKIAA0667   523    HpHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTL    559  

HEAT: domain 7 of 12, from 571 to 609: score 2.3, E = 1.2e+02
                   *->e.lldellplllklln..DpdpeVReaAaeaLgalaevl<-*
                      e+++ e+  + l  l+ +D d eV+e A++++g+l+ +l   
   mKIAA0667   571    EpYVGEMSTATLARLRatDLDQEVKERAISCVGHLVGHL    609  

HEAT: domain 8 of 12, from 654 to 690: score 8.8, E = 14
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      +++l e lp+l + l+ +    R+a++ aL ala+     
   mKIAA0667   654    QpILAEALPILASFLRKNQRALRLATLAALDALAQSQ    690  

HEAT: domain 9 of 12, from 863 to 899: score 20.0, E = 0.055
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                       + + el  +ll++l++p+++VR+aAa+aLg++       
   mKIAA0667   863    PgPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGN    899  

HEAT_PBS: domain 2 of 2, from 884 to 913: score 13.2, E = 6.2
                   *->vRraAaraLgalgd...peAipaLleaLed<-*
                      vR+aAa+aLg+ g+++ p+ +p Ll+  e    
   mKIAA0667   884    VRAAAAYALGRVGAgnlPDFLPFLLAQIEA    913  

HEAT: domain 10 of 12, from 938 to 974: score 16.3, E = 0.74
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      +++++++  ll++ +++p++  R+ +ae++g+l+ v    
   mKIAA0667   938    KpYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVN    974  

HEAT: domain 11 of 12, from 1013 to 1049: score 13.3, E = 3.3
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      ++ll++++  +++ l+Dpd +VR+a++  + + + +    
   mKIAA0667  1013    DpLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNK    1049 

HEAT: domain 12 of 12, from 1073 to 1108: score 1.9, E = 1.3e+02
                   *->e.lldellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      + +++  + ++ +  +D   +VR+aA+e++ +l+e +   
   mKIAA0667  1073    DlIREVEMGPFKHTVDDGL-DVRKAAFECMYSLLESC    1108 

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