hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbf/mbf03424/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0621  ( 847 res)   mbf03424

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGAP   GTPase-activator protein for Rho-like GTPase   231.4    7.6e-65   1
SH3      Src homology 3 domains                          61.8    8.8e-14   1
PH       Pleckstrin homology domain.                     43.0      4e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/1     299   404 ..     1    82 []    43.0    4e-08
RhoGAP     1/1     420   598 ..     1   193 []   231.4  7.6e-65
SH3        1/1     792   847 .]     1    58 []    61.8  8.8e-14

Alignments of top-scoring domains:
PH: domain 1 of 1, from 299 to 404: score 43.0, E = 4e-08
                   *->vikeGwLlkks....k.swkkryfvLfn....gvLlyyksk.....k
                       ++eG+L+++++++ ++sw k+y++  +++++ +++ +++k+++++ 
   mKIAA0621   299    YTMEGYLYVQEkrhfGtSWVKHYCTYQRdskqITMVPFDQKsggkgG 345  

                   pkgsipLsgcsvre.p......cFeivt.dr..tlllqAeseeereeWve
                     +s+ L++c+ r++++ +++ cF +   dr++++++qA see+r+ W+e
   mKIAA0621   346 EDESVTLKSCTRRKtDsiekrfCFDVEAvDRpgVITMQALSEEDRRLWME 395  

                   alqsaiaka<-*
                   a+      +   
   mKIAA0621   396 AMDGREPVY    404  

RhoGAP: domain 1 of 1, from 420 to 598: score 231.4, E = 7.6e-65
                   *->spiPiivekCieylekrGldteGIYRvsGsksrvkeLreafdsged.
                      s   +i++kCi+++e+rG++++G+YR+ G++srv++L++ +  ++  
   mKIAA0621   420    SIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKAa 466  

                   dldsldesiteesedleeydvhdvAglLKlyLReLPePLltfelyeefie
                   +++++d         + e+++ +v+++LK+yLR LP PL+ ++ ++ fi+
   mKIAA0621   467 SETETD--------ICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFIK 508  

                   aaklyqieatsrkqseksedeeerlralrellslLPpanratLryLl.HL
                   aakl              e+ e+r+ +++ l+++LP+ nr++L++L++HL
   mKIAA0621   509 AAKL--------------ENQETRVSEIHSLVHRLPEKNRQMLQLLMnHL 544  

                   nrVaehsevNkMtarNLAivFgPtLlrpp......ltdikhqnkvvetli
                   ++Va+++++N+Mt+ NL++vFgPtLlrp++++   ++dik+qn+v+e+li
   mKIAA0621   545 ANVANNHKQNLMTVANLGVVFGPTLLRPQeetvaaIMDIKFQNIVIEILI 594  

                   enad<-*
                   en++   
   mKIAA0621   595 ENHE    598  

SH3: domain 1 of 1, from 792 to 847: score 61.8, E = 8.8e-14
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleks.ddgWweGelnrtGke
                      ++++AlY+++a+++ ELsF++G ++  +  s+++gW+eG+ln  Gk+
   mKIAA0621   792    RKAKALYACQAEHDSELSFTAGTVFDNVHPSqEPGWLEGTLN--GKT 836  

                   GlfPsnYVeeie<-*
                   Gl+P nYV e     
   mKIAA0621   837 GLIPENYV-EFL    847  

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