Result of FASTA (omim) for
pFN21AB9000
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9000, 418 aa
1>>>pF1KB9000 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4032+/-0.000363; mu= 22.9656+/- 0.023
mean_var=94.4118+/-23.739, 0's: 0 Z-trim(114.3): 522 B-trim: 2611 in 2/53
Lambda= 0.131996
statistics sampled from 23291 (24036) to 23291 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.282), width: 16
Scan time: 6.400
The best scores are: opt bits E(85289)
NP_000697 (OMIM: 600821) vasopressin V1a receptor ( 418) 2878 558.7 9.7e-159
NP_000698 (OMIM: 600264) vasopressin V1b receptor ( 424) 1252 249.1 1.6e-65
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389) 1249 248.4 2.3e-65
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389) 1249 248.4 2.3e-65
NP_001139623 (OMIM: 300538,300539,304800) vasopres ( 309) 784 159.8 8.9e-39
XP_006724891 (OMIM: 300538,300539,304800) PREDICTE ( 371) 784 159.9 9.9e-39
NP_000045 (OMIM: 300538,300539,304800) vasopressin ( 371) 784 159.9 9.9e-39
NP_997055 (OMIM: 608584,608595) neuropeptide S rec ( 371) 409 88.5 3.1e-17
NP_997056 (OMIM: 608584,608595) neuropeptide S rec ( 377) 409 88.5 3.1e-17
NP_001287864 (OMIM: 608584,608595) neuropeptide S ( 390) 409 88.5 3.2e-17
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 348 76.8 9.1e-14
NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 320 71.5 4e-12
NP_001287862 (OMIM: 608584,608595) neuropeptide S ( 366) 313 70.2 9.9e-12
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 311 69.8 1.3e-11
NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 300 67.8 5.9e-11
XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 292 66.2 1.7e-10
NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 292 66.2 1.7e-10
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 291 66.0 1.8e-10
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 291 66.0 1.8e-10
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 290 65.8 2.1e-10
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 290 65.8 2.1e-10
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 290 65.8 2.2e-10
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 290 65.8 2.2e-10
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 290 65.8 2.2e-10
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 290 65.8 2.2e-10
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 290 65.9 2.2e-10
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 290 65.9 2.2e-10
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 290 65.9 2.2e-10
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 290 65.9 2.3e-10
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 290 66.0 2.4e-10
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 290 66.0 2.4e-10
NP_001012781 (OMIM: 138850,146110) gonadotropin-re ( 249) 286 64.8 2.8e-10
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 286 65.0 3.6e-10
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 286 65.1 3.7e-10
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 284 64.5 3.8e-10
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 284 64.7 5e-10
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 282 64.2 5.7e-10
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 282 64.3 6.1e-10
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 279 63.8 9.8e-10
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 279 63.8 1e-09
NP_061822 (OMIM: 600896) urotensin-2 receptor [Hom ( 389) 274 62.8 1.8e-09
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 270 62.0 2.9e-09
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 270 62.0 2.9e-09
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 270 62.0 2.9e-09
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 270 62.0 2.9e-09
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 270 62.0 2.9e-09
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 270 62.0 3e-09
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 270 62.0 3e-09
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 270 62.0 3e-09
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 270 62.0 3e-09
>>NP_000697 (OMIM: 600821) vasopressin V1a receptor [Hom (418 aa)
initn: 2878 init1: 2878 opt: 2878 Z-score: 2970.8 bits: 558.7 E(85289): 9.7e-159
Smith-Waterman score: 2878; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB9 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
310 320 330 340 350 360
370 380 390 400 410
pF1KB9 QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
370 380 390 400 410
>>NP_000698 (OMIM: 600264) vasopressin V1b receptor [Hom (424 aa)
initn: 1257 init1: 844 opt: 1252 Z-score: 1297.3 bits: 249.1 E(85289): 1.6e-65
Smith-Waterman score: 1254; 51.4% identity (75.5% similar) in 383 aa overlap (14-386:2-377)
10 20 30 40 50 60
pF1KB9 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
.:.: : :. : : . . ... : :.:::::.::.:::.
NP_000 MDSGPLWD----ANPTPRGTLSAPNATTPWLG-RDEELAKVEIGVLAT
10 20 30 40
70 80 90 100 110 120
pF1KB9 TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
....:. :: .:::.: . :: ::::::. ::.:.:::::.::::::. :::::::.::
NP_000 VLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
: :::.::.:::..::::.:::..:: :::.::::::..::::.. . :.::: :.:. .
NP_000 DLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
.: :: :.::. :: . . . :::: : ::: :::.:: : .::: ::..: .::..::
NP_000 FSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLIC
170 180 190 200 210 220
250 260 270 280 290
pF1KB9 YNIWCNVRGKTASRQSKG---------AEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVK
..: :.. :: . . : . .. .: .: : :::...::::::::::
NP_000 HEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRG--LPSRVSSINTISRAKIRTVK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 MTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFF
:::::: :::.:::::: .::::::: . .: : ..::. :::.::::::::::: :
NP_000 MTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB9 SGHLLQDCVQSFPCCQNMKEKFNKEDTD-SMSRRQTFYSNNRSPTNSTGMWKDSPKSSKS
..::: .. . :: . . .. .. .: :.: :.:
NP_000 NSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRP
350 360 370 380 390 400
pF1KB9 IKFIPVST
NP_000 RPEESPRDLELADGEGTAETIIF
410 420
>>XP_011532064 (OMIM: 167055) PREDICTED: oxytocin recept (389 aa)
initn: 1060 init1: 504 opt: 1249 Z-score: 1294.6 bits: 248.4 E(85289): 2.3e-65
Smith-Waterman score: 1249; 49.7% identity (75.5% similar) in 380 aa overlap (25-398:13-382)
10 20 30 40 50
pF1KB9 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGN---GPPRDVRNEELAKLEIAV
:.:.: : .::: :::: ::: ::..:.::
XP_011 MEGALAANWSAEAANAS-AAPPGAEGNRTAGPPR--RNEALARVEVAV
10 20 30 40
60 70 80 90 100 110
pF1KB9 LAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRF
: . . .:. ::. :::::. : .: ::. .:..:::.:::.:: ::::::. ::::.::
XP_011 LCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 RGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVL
::: :::.::.::: :::::.:.:..:. :: .:.:.::..:.. : .:: . :.:.
XP_011 YGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 SFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYG
.: :.:: .::. :: . . ::::.:::::: .::.::.: .....::..:..:::
XP_011 CLVASAPQVHIFSLREVAD--GVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 FICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIV
.: ..:: :.: :::. . : ....: . : . ::::: ::.::::::::::.::
XP_011 LISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 TAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQ
:.::::.:::..::::::: . .: .. :. ::.::::::::::::.:.:::..
XP_011 LAFIVCWTPFFFVQMWSVWDANA---PKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFH
290 300 310 320 330
360 370 380 390 400 410
pF1KB9 DCVQSFPCCQNMKEKFNKEDTDSMSRRQ---TFYSNNRSPTNSTGMWKDSPKSSKSIKFI
. :: : ::. : . : :... .: ..:: .. .
XP_011 ELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
340 350 360 370 380
pF1KB9 PVST
>>NP_000907 (OMIM: 167055) oxytocin receptor [Homo sapie (389 aa)
initn: 1060 init1: 504 opt: 1249 Z-score: 1294.6 bits: 248.4 E(85289): 2.3e-65
Smith-Waterman score: 1249; 49.7% identity (75.5% similar) in 380 aa overlap (25-398:13-382)
10 20 30 40 50
pF1KB9 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGN---GPPRDVRNEELAKLEIAV
:.:.: : .::: :::: ::: ::..:.::
NP_000 MEGALAANWSAEAANAS-AAPPGAEGNRTAGPPR--RNEALARVEVAV
10 20 30 40
60 70 80 90 100 110
pF1KB9 LAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRF
: . . .:. ::. :::::. : .: ::. .:..:::.:::.:: ::::::. ::::.::
NP_000 LCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 RGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVL
::: :::.::.::: :::::.:.:..:. :: .:.:.::..:.. : .:: . :.:.
NP_000 YGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 SFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYG
.: :.:: .::. :: . . ::::.:::::: .::.::.: .....::..:..:::
NP_000 CLVASAPQVHIFSLREVAD--GVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 FICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIV
.: ..:: :.: :::. . : ....: . : . ::::: ::.::::::::::.::
NP_000 LISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 TAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQ
:.::::.:::..::::::: . .: .. :. ::.::::::::::::.:.:::..
NP_000 LAFIVCWTPFFFVQMWSVWDANA---PKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFH
290 300 310 320 330
360 370 380 390 400 410
pF1KB9 DCVQSFPCCQNMKEKFNKEDTDSMSRRQ---TFYSNNRSPTNSTGMWKDSPKSSKSIKFI
. :: : ::. : . : :... .: ..:: .. .
NP_000 ELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
340 350 360 370 380
pF1KB9 PVST
>>NP_001139623 (OMIM: 300538,300539,304800) vasopressin (309 aa)
initn: 732 init1: 336 opt: 784 Z-score: 817.1 bits: 159.8 E(85289): 8.9e-39
Smith-Waterman score: 784; 43.1% identity (73.7% similar) in 281 aa overlap (42-318:28-298)
20 30 40 50 60 70
pF1KB9 SGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSS
: :.:. ::. :.:.:...:....:.:.
NP_001 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGL
10 20 30 40 50
80 90 100 110 120
pF1KB9 VLLALHRTPRKT--SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKH
:: :: : :. . .:.:: :: :::::::.::::::. : : :::::: :::.::.
NP_001 VLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQP--ARRSRLMIAAAWVLSFVLSTPQYF
::. ::.::.::...:: ::. :.:.:. . .. :. .: . .::..:..:: :: :
NP_001 LQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNR-PVLVAWAFSLLLSLPQLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 VFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNV
.:.. .:.. . . :::: : .::: :.::::.. .::::.. ...: .: .: ..
NP_001 IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 RGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPF
. : :... : . : .: .. .: : .::.::.:::..:..:::::
NP_001 VPGPSER--PGGRRRG--RRTG---SPGEGA--HVSAAVAKTVRMTLVIVVVYVLCWAPF
240 250 260 270 280
310 320 330 340 350 360
pF1KB9 FIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQ
:..:.:..:::
NP_001 FLVQLWAAWDPEAPLEGGCSRG
290 300
>>XP_006724891 (OMIM: 300538,300539,304800) PREDICTED: v (371 aa)
initn: 820 init1: 336 opt: 784 Z-score: 816.3 bits: 159.9 E(85289): 9.9e-39
Smith-Waterman score: 882; 42.2% identity (72.6% similar) in 329 aa overlap (42-366:28-342)
20 30 40 50 60 70
pF1KB9 SGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSS
: :.:. ::. :.:.:...:....:.:.
XP_006 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGL
10 20 30 40 50
80 90 100 110 120
pF1KB9 VLLALHRTPRKT--SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKH
:: :: : :. . .:.:: :: :::::::.::::::. : : :::::: :::.::.
XP_006 VLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQP--ARRSRLMIAAAWVLSFVLSTPQYF
::. ::.::.::...:: ::. :.:.:. . .. :. .: ...: :..:..:: :: :
XP_006 LQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVA-WAFSLLLSLPQLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 VFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNV
.:.. .:.. . . :::: : .::: :.::::.. .::::.. ...: .: .: ..
XP_006 IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 RGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPF
. : :... : . : .: .. .: : .::.::.:::..:..:::::
XP_006 VPGPSERP--GGRRRG--RRTG---SPGEGA--HVSAAVAKTVRMTLVIVVVYVLCWAPF
240 250 260 270 280
310 320 330 340 350 360
pF1KB9 FIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQ
:..:.:..::: . :. ... ::.::::: ::::: ::. . .. ..:. ::
XP_006 FLVQLWAAWDPEA---PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSE-LRSLLCCA
290 300 310 320 330 340
370 380 390 400 410
pF1KB9 NMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
XP_006 RGRTPPSLGPQDESCTTASSSLAKDTSS
350 360 370
>>NP_000045 (OMIM: 300538,300539,304800) vasopressin V2 (371 aa)
initn: 820 init1: 336 opt: 784 Z-score: 816.3 bits: 159.9 E(85289): 9.9e-39
Smith-Waterman score: 882; 42.2% identity (72.6% similar) in 329 aa overlap (42-366:28-342)
20 30 40 50 60 70
pF1KB9 SGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSS
: :.:. ::. :.:.:...:....:.:.
NP_000 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGL
10 20 30 40 50
80 90 100 110 120
pF1KB9 VLLALHRTPRKT--SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKH
:: :: : :. . .:.:: :: :::::::.::::::. : : :::::: :::.::.
NP_000 VLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQP--ARRSRLMIAAAWVLSFVLSTPQYF
::. ::.::.::...:: ::. :.:.:. . .. :. .: ...: :..:..:: :: :
NP_000 LQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVA-WAFSLLLSLPQLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 VFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNV
.:.. .:.. . . :::: : .::: :.::::.. .::::.. ...: .: .: ..
NP_000 IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 RGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPF
. : :... : . : .: .. .: : .::.::.:::..:..:::::
NP_000 VPGPSERP--GGRRRG--RRTG---SPGEGA--HVSAAVAKTVRMTLVIVVVYVLCWAPF
240 250 260 270 280
310 320 330 340 350 360
pF1KB9 FIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQ
:..:.:..::: . :. ... ::.::::: ::::: ::. . .. ..:. ::
NP_000 FLVQLWAAWDPEA---PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSE-LRSLLCCA
290 300 310 320 330 340
370 380 390 400 410
pF1KB9 NMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
NP_000 RGRTPPSLGPQDESCTTASSSLAKDTSS
350 360 370
>>NP_997055 (OMIM: 608584,608595) neuropeptide S recepto (371 aa)
initn: 521 init1: 238 opt: 409 Z-score: 430.4 bits: 88.5 E(85289): 3.1e-17
Smith-Waterman score: 551; 31.9% identity (62.3% similar) in 313 aa overlap (54-365:52-341)
30 40 50 60 70 80
pF1KB9 GAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT
.. .: : :. ...::: ::.. : .:
NP_997 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKK-
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLV
::: .:. .:...: ... ..: .. : .: : .:: .::::..::: ..::.:.::
NP_997 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB9 VMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDC
.. ::: :. .:.: :: ...:..:. :: :::..: : ..:. ..: .:
NP_997 SLSIDRYHAIVYPMKFLQGE-KQARVLIVIAWSLSFLFSIPTLIIFGKRTLSN--GEVQC
150 160 170 180 190
210 220 230 240 250 260
pF1KB9 WATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAG
:: . . :.: .. .. :..:.. ::.. .:: .:: : .
NP_997 WALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWI---------KSKTYETVI
200 210 220 230 240
270 280 290 300 310 320
pF1KB9 VAFQKGFLLAPCVSSVKS-ISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVW
. : : : : .. ::.:::...:....:. :.: ::.:.:.... . .. .
NP_997 SNCSDGKL---CSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDT
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB9 TESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMS
: .. : : .::: :: :: ::. . ::::
NP_997 QERFYASVIIQNL-PALNSAINPLIYCVFSSSI------SFPCREQRSQDSRMTFRERTE
310 320 330 340 350
390 400 410
pF1KB9 RRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
NP_997 RHEMQILSKPEFI
360 370
>>NP_997056 (OMIM: 608584,608595) neuropeptide S recepto (377 aa)
initn: 521 init1: 238 opt: 409 Z-score: 430.3 bits: 88.5 E(85289): 3.1e-17
Smith-Waterman score: 551; 31.9% identity (62.3% similar) in 313 aa overlap (54-365:52-341)
30 40 50 60 70 80
pF1KB9 GAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT
.. .: : :. ...::: ::.. : .:
NP_997 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKK-
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLV
::: .:. .:...: ... ..: .. : .: : .:: .::::..::: ..::.:.::
NP_997 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB9 VMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDC
.. ::: :. .:.: :: ...:..:. :: :::..: : ..:. ..: .:
NP_997 SLSIDRYHAIVYPMKFLQGE-KQARVLIVIAWSLSFLFSIPTLIIFGKRTLSN--GEVQC
150 160 170 180 190
210 220 230 240 250 260
pF1KB9 WATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAG
:: . . :.: .. .. :..:.. ::.. .:: .:: : .
NP_997 WALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWI---------KSKTYETVI
200 210 220 230 240
270 280 290 300 310 320
pF1KB9 VAFQKGFLLAPCVSSVKS-ISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVW
. : : : : .. ::.:::...:....:. :.: ::.:.:.... . .. .
NP_997 SNCSDGKL---CSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDT
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB9 TESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMS
: .. : : .::: :: :: ::. . ::::
NP_997 QERFYASVIIQNL-PALNSAINPLIYCVFSSSI------SFPCRVIRLRQLQEAALMLCP
310 320 330 340 350
390 400 410
pF1KB9 RRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
NP_997 QRENWKGTWPGVPSWALPR
360 370
>>NP_001287864 (OMIM: 608584,608595) neuropeptide S rece (390 aa)
initn: 508 init1: 238 opt: 409 Z-score: 430.1 bits: 88.5 E(85289): 3.2e-17
Smith-Waterman score: 564; 30.4% identity (60.7% similar) in 359 aa overlap (54-405:52-387)
30 40 50 60 70 80
pF1KB9 GAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT
.. .: : :. ...::: ::.. : .:
NP_001 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRR-KKK
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 SRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLV
::: .:. .:...: ... ..: .. : .: : .:: .::::..::: ..::.:.::
NP_001 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB9 VMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDC
.. ::: :. .:.: :: ...:..:. :: :::..: : ..:. ..: .:
NP_001 SLSIDRYHAIVYPMKFLQGE-KQARVLIVIAWSLSFLFSIPTLIIFGKRTLSN--GEVQC
150 160 170 180 190
210 220 230 240 250 260
pF1KB9 WATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAG
:: . . :.: .. .. :..:.. ::.. .:: .:: : .
NP_001 WALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWI---------KSKTYETVI
200 210 220 230 240
270 280 290 300 310 320
pF1KB9 VAFQKGFLLAPCVSSVKS-ISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVW
. : : : : .. ::.:::...:....:. :.: ::.:.:.... . .. .
NP_001 SNCSDGKL---CSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDT
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB9 TESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSM-
: .. : : .::: :: :: ::. . :::: : . . :.. .
NP_001 QERFYASVIIQNL-PALNSAINPLIYCVFSSSI------SFPCRANSSVYLLACDVSVLW
310 320 330 340 350
390 400 410
pF1KB9 -----SRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
:.... : :. .. ::. .: :
NP_001 ALVLTSEKESCESWRRKGAKITGFQNDVPGEN
360 370 380 390
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:57:17 2016 done: Fri Nov 4 16:57:18 2016
Total Scan time: 6.400 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]