Result of FASTA (omim) for
pFN21AB5631
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5631, 1036 aa
1>>>pF1KB5631 1036 - 1036 aa - 1036 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2655+/-0.000489; mu= 21.8879+/- 0.030
mean_var=68.8143+/-13.987, 0's: 0 Z-trim(108.1): 30 B-trim: 425 in 1/53
Lambda= 0.154609
statistics sampled from 16197 (16214) to 16197 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.524), E-opt: 0.2 (0.19), width: 16
Scan time: 10.980
The best scores are: opt bits E(85289)
XP_005247591 (OMIM: 602382) PREDICTED: phospholipa (1036) 6974 1565.8 0
NP_001123553 (OMIM: 602382) phospholipase D1 isofo (1036) 6974 1565.8 0
XP_016862112 (OMIM: 602382) PREDICTED: phospholipa ( 933) 6224 1398.5 0
XP_011511200 (OMIM: 602382) PREDICTED: phospholipa ( 969) 3937 888.4 0
XP_011511199 (OMIM: 602382) PREDICTED: phospholipa ( 971) 3937 888.4 0
NP_002653 (OMIM: 602382) phospholipase D1 isoform (1074) 3937 888.4 0
XP_005247590 (OMIM: 602382) PREDICTED: phospholipa (1074) 3937 888.4 0
XP_016862113 (OMIM: 602382) PREDICTED: phospholipa ( 657) 3046 689.5 1.6e-197
XP_011511201 (OMIM: 602382) PREDICTED: phospholipa ( 657) 3046 689.5 1.6e-197
XP_005256753 (OMIM: 602384) PREDICTED: phospholipa ( 548) 1847 422.0 4.4e-117
NP_002654 (OMIM: 602384) phospholipase D2 isoform ( 933) 1847 422.2 6.7e-117
NP_001230037 (OMIM: 602384) phospholipase D2 isofo ( 922) 1801 411.9 8.2e-114
XP_016880253 (OMIM: 602384) PREDICTED: phospholipa ( 537) 1448 333.0 2.7e-90
>>XP_005247591 (OMIM: 602382) PREDICTED: phospholipase D (1036 aa)
initn: 6974 init1: 6974 opt: 6974 Z-score: 8399.5 bits: 1565.8 E(85289): 0
Smith-Waterman score: 6974; 100.0% identity (100.0% similar) in 1036 aa overlap (1-1036:1-1036)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL
970 980 990 1000 1010 1020
1030
pF1KB5 PSVGTKEAIVPMEVWT
::::::::::::::::
XP_005 PSVGTKEAIVPMEVWT
1030
>>NP_001123553 (OMIM: 602382) phospholipase D1 isoform b (1036 aa)
initn: 6974 init1: 6974 opt: 6974 Z-score: 8399.5 bits: 1565.8 E(85289): 0
Smith-Waterman score: 6974; 100.0% identity (100.0% similar) in 1036 aa overlap (1-1036:1-1036)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL
970 980 990 1000 1010 1020
1030
pF1KB5 PSVGTKEAIVPMEVWT
::::::::::::::::
NP_001 PSVGTKEAIVPMEVWT
1030
>>XP_016862112 (OMIM: 602382) PREDICTED: phospholipase D (933 aa)
initn: 6222 init1: 6222 opt: 6224 Z-score: 7496.1 bits: 1398.5 E(85289): 0
Smith-Waterman score: 6224; 99.1% identity (99.5% similar) in 933 aa overlap (1-932:1-933)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
850 860 870 880 890 900
910 920 930 940 950
pF1KB5 SVMDGKEYQAGRFARGLRLQCFRVVLGY-LDDPSEDIQDPVSDKFFKEVWVSTAARNATI
::::::::::::::::::::::: . ..::
XP_016 SVMDGKEYQAGRFARGLRLQCFRSKMTPGVEDP
910 920 930
960 970 980 990 1000 1010
pF1KB5 YDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESL
>>XP_011511200 (OMIM: 602382) PREDICTED: phospholipase D (969 aa)
initn: 3931 init1: 3931 opt: 3937 Z-score: 4738.9 bits: 888.4 E(85289): 0
Smith-Waterman score: 6131; 95.3% identity (95.7% similar) in 969 aa overlap (1-931:1-966)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
550 560 570 580 590 600
590 600 610 620
pF1KB5 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
.:::::::::::::::::::::::::::::::::::::
XP_011 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB5 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB5 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB5 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
790 800 810 820 830 840
810 820 830 840 850 860
pF1KB5 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
850 860 870 880 890 900
870 880 890 900 910 920
pF1KB5 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
910 920 930 940 950 960
930 940 950 960 970 980
pF1KB5 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
:..:.
XP_011 S---GFIDEEKN
>>XP_011511199 (OMIM: 602382) PREDICTED: phospholipase D (971 aa)
initn: 3931 init1: 3931 opt: 3937 Z-score: 4738.9 bits: 888.4 E(85289): 0
Smith-Waterman score: 6133; 95.2% identity (95.6% similar) in 971 aa overlap (1-932:1-971)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
550 560 570 580 590 600
590 600 610 620
pF1KB5 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
.:::::::::::::::::::::::::::::::::::::
XP_011 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB5 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB5 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB5 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
790 800 810 820 830 840
810 820 830 840 850 860
pF1KB5 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
850 860 870 880 890 900
870 880 890 900 910 920
pF1KB5 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
910 920 930 940 950 960
930 940 950 960 970 980
pF1KB5 RVVLGY-LDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDF
: . ..::
XP_011 RSKMTPGVEDP
970
>>NP_002653 (OMIM: 602382) phospholipase D1 isoform a [H (1074 aa)
initn: 3931 init1: 3931 opt: 3937 Z-score: 4738.2 bits: 888.4 E(85289): 0
Smith-Waterman score: 6835; 96.3% identity (96.4% similar) in 1068 aa overlap (1-1030:1-1068)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS----------------
::::::::::::::::::::::::::::::::::::::::::::
NP_002 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
550 560 570 580 590 600
590 600 610 620
pF1KB5 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
.:::::::::::::::::::::::::::::::::::::
NP_002 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB5 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB5 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB5 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
790 800 810 820 830 840
810 820 830 840 850 860
pF1KB5 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
850 860 870 880 890 900
870 880 890 900 910 920
pF1KB5 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
910 920 930 940 950 960
930 940 950 960 970 980
pF1KB5 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
970 980 990 1000 1010 1020
990 1000 1010 1020 1030
pF1KB5 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
1030 1040 1050 1060 1070
>>XP_005247590 (OMIM: 602382) PREDICTED: phospholipase D (1074 aa)
initn: 3931 init1: 3931 opt: 3937 Z-score: 4738.2 bits: 888.4 E(85289): 0
Smith-Waterman score: 6835; 96.3% identity (96.4% similar) in 1068 aa overlap (1-1030:1-1068)
10 20 30 40 50 60
pF1KB5 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
490 500 510 520 530 540
550 560 570 580
pF1KB5 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
550 560 570 580 590 600
590 600 610 620
pF1KB5 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
.:::::::::::::::::::::::::::::::::::::
XP_005 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB5 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB5 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB5 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
790 800 810 820 830 840
810 820 830 840 850 860
pF1KB5 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
850 860 870 880 890 900
870 880 890 900 910 920
pF1KB5 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
910 920 930 940 950 960
930 940 950 960 970 980
pF1KB5 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
970 980 990 1000 1010 1020
990 1000 1010 1020 1030
pF1KB5 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
1030 1040 1050 1060 1070
>>XP_016862113 (OMIM: 602382) PREDICTED: phospholipase D (657 aa)
initn: 3068 init1: 3040 opt: 3046 Z-score: 3667.3 bits: 689.5 E(85289): 1.6e-197
Smith-Waterman score: 4056; 94.1% identity (94.2% similar) in 657 aa overlap (418-1036:1-657)
390 400 410 420 430 440
pF1KB5 FLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKV
::::::::::::::::::::::::::::::
XP_016 MLYKEVELALGINSEYTKRTLMRLHPNIKV
10 20 30
450 460 470 480 490 500
pF1KB5 MRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGP
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB5 SLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLH
100 110 120 130 140 150
570 580
pF1KB5 RHHLHDADSISSIDSTS--------------------------------------NTGSI
::::::::::::::::: .::::
XP_016 RHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSI
160 170 180 190 200 210
590 600 610 620 630 640
pF1KB5 RSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHG
220 230 240 250 260 270
650 660 670 680 690 700
pF1KB5 KAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRS
280 290 300 310 320 330
710 720 730 740 750 760
pF1KB5 AADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILK
340 350 360 370 380 390
770 780 790 800 810 820
pF1KB5 AHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGN
400 410 420 430 440 450
830 840 850 860 870 880
pF1KB5 QWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEM
460 470 480 490 500 510
890 900 910 920 930 940
pF1KB5 AVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVW
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KB5 VSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQF
580 590 600 610 620 630
1010 1020 1030
pF1KB5 PFYFLSEESLLPSVGTKEAIVPMEVWT
:::::::::::::::::::::::::::
XP_016 PFYFLSEESLLPSVGTKEAIVPMEVWT
640 650
>>XP_011511201 (OMIM: 602382) PREDICTED: phospholipase D (657 aa)
initn: 3068 init1: 3040 opt: 3046 Z-score: 3667.3 bits: 689.5 E(85289): 1.6e-197
Smith-Waterman score: 4056; 94.1% identity (94.2% similar) in 657 aa overlap (418-1036:1-657)
390 400 410 420 430 440
pF1KB5 FLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKV
::::::::::::::::::::::::::::::
XP_011 MLYKEVELALGINSEYTKRTLMRLHPNIKV
10 20 30
450 460 470 480 490 500
pF1KB5 MRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGP
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB5 SLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLH
100 110 120 130 140 150
570 580
pF1KB5 RHHLHDADSISSIDSTS--------------------------------------NTGSI
::::::::::::::::: .::::
XP_011 RHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSI
160 170 180 190 200 210
590 600 610 620 630 640
pF1KB5 RSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHG
220 230 240 250 260 270
650 660 670 680 690 700
pF1KB5 KAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRS
280 290 300 310 320 330
710 720 730 740 750 760
pF1KB5 AADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILK
340 350 360 370 380 390
770 780 790 800 810 820
pF1KB5 AHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGN
400 410 420 430 440 450
830 840 850 860 870 880
pF1KB5 QWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEM
460 470 480 490 500 510
890 900 910 920 930 940
pF1KB5 AVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVW
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KB5 VSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQF
580 590 600 610 620 630
1010 1020 1030
pF1KB5 PFYFLSEESLLPSVGTKEAIVPMEVWT
:::::::::::::::::::::::::::
XP_011 PFYFLSEESLLPSVGTKEAIVPMEVWT
640 650
>>XP_005256753 (OMIM: 602384) PREDICTED: phospholipase D (548 aa)
initn: 2016 init1: 1041 opt: 1847 Z-score: 2223.1 bits: 422.0 E(85289): 4.4e-117
Smith-Waterman score: 2176; 53.6% identity (73.6% similar) in 633 aa overlap (404-1036:1-548)
380 390 400 410 420 430
pF1KB5 EEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEY
.:::::..:::. :.:.::::::::::: :
XP_005 MLKRKAEEGVRVSILLFKEVELALGINSGY
10 20 30
440 450 460 470 480 490
pF1KB5 TKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHR
.::.:: ::::::::::::.:. ::::::::...:: :::.::.::::::::: ..:
XP_005 SKRALMLLHPNIKVMRHPDQVT----LWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYR
40 50 60 70 80
500 510 520 530 540 550
pF1KB5 LTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGK
:::.:. :. : .: ::.
XP_005 LTDLGD-----SSESAASQPPT--------------------------------------
90 100
560 570 580 590 600 610
pF1KB5 PRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELHGETRFWHGKDYCN
:: :: .. : . : :: :::: :
XP_005 PRP------------------DSPATPDLSHNQ-----------------FFWLGKDYSN
110 120
620 630 640 650 660 670
pF1KB5 FVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKY
.. :::::::.:: ::::: .::::::.:.. .::: :::.:::::::::::: :.::
XP_005 LITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKY
130 140 150 160 170 180
680 690 700 710 720 730
pF1KB5 RSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIE
.. .::.::::: .::..: . .::. ..::.:::. :::: :.:: ::.:.:.
XP_005 KTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGT--LENSILNAYLHTIR
190 200 210 220 230 240
740 750 760 770 780 790
pF1KB5 NSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDI
.:.:..::::::::::.: ..:.::.:: :..::::::... :::::..::::::::::
XP_005 ESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDI
250 260 270 280 290 300
800 810 820 830 840 850
pF1KB5 STGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTE
::::::..:::.::.:::.:::: ::: .::: .:. : .:::.::::::.:: :. :.:
XP_005 STGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSE
310 320 330 340 350 360
860 870 880 890 900 910
pF1KB5 LIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRF
:::.:::.::::: :::::::::::::.:::::::.::...:::: ::.:.: :::::::
XP_005 LIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRF
370 380 390 400 410 420
920 930 940 950 960 970
pF1KB5 ARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVH
: .:: .:: :.:: :. :..::. : ::. .: . : ::.::...:::::.. ..
XP_005 ALSLRKHCFGVILGANTRPDLDLRDPICDDFFQ-LWQDMAESNANIYEQIFRCLPSNATR
430 440 450 460 470 480
980 990 1000 1010 1020 1030
pF1KB5 NLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPME
.: ::... :: .: :. :: ...: ::.::. :: .::::: .:.::...:.:
XP_005 SLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLE
490 500 510 520 530 540
pF1KB5 VWT
:::
XP_005 VWT
1036 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:46:08 2016 done: Thu Nov 3 17:46:10 2016
Total Scan time: 10.980 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]