# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/fk12643.fasta.nr -Q ../query/KIAA1957.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1957, 481 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7822758 sequences Expectation_n fit: rho(ln(x))= 5.7818+/-0.000197; mu= 9.5872+/- 0.011 mean_var=104.5054+/-20.033, 0's: 37 Z-trim: 47 B-trim: 83 in 1/65 Lambda= 0.125460 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|119581604|gb|EAW61200.1| hCG1659953, isoform CR ( 613) 3084 568.8 1.4e-159 gi|21739976|emb|CAD39008.1| hypothetical protein [ ( 405) 2671 493.8 3.3e-137 gi|149034681|gb|EDL89418.1| rCG29198 [Rattus norve ( 422) 2531 468.5 1.5e-129 gi|81889002|sp|Q5HZI2.1|NLF3_MOUSE RecName: Full=N ( 419) 2518 466.2 7.4e-129 gi|26325880|dbj|BAC26694.1| unnamed protein produc ( 419) 2502 463.3 5.5e-128 gi|194668533|ref|XP_597854.4| PREDICTED: similar t ( 420) 2467 456.9 4.5e-126 gi|73987619|ref|XP_542222.2| PREDICTED: similar to ( 423) 2388 442.6 9e-122 gi|126323770|ref|XP_001376103.1| PREDICTED: simila ( 438) 1708 319.6 1e-84 gi|118103197|ref|XP_425894.2| PREDICTED: similar t ( 413) 1646 308.3 2.4e-81 gi|125865234|ref|XP_697197.2| PREDICTED: similar t ( 421) 1440 271.0 4.1e-70 gi|149578736|ref|XP_001506634.1| PREDICTED: simila ( 437) 1439 270.9 4.7e-70 gi|189546677|ref|XP_685829.3| PREDICTED: similar t ( 437) 1418 267.1 6.6e-69 gi|47225609|emb|CAG07952.1| unnamed protein produc ( 436) 1403 264.4 4.3e-68 gi|197246711|gb|AAI68583.1| Unknown (protein for M ( 438) 900 173.3 1.1e-40 gi|47228372|emb|CAG07767.1| unnamed protein produc ( 429) 693 135.8 2.1e-29 gi|122136139|sp|Q2KJ18.1|NLF1_BOVIN RecName: Full= ( 364) 546 109.2 1.9e-21 gi|194035062|ref|XP_001926398.1| PREDICTED: simila ( 372) 532 106.6 1.1e-20 gi|109081370|ref|XP_001101238.1| PREDICTED: simila ( 364) 516 103.7 8.1e-20 gi|109081368|ref|XP_001101156.1| PREDICTED: simila ( 371) 514 103.4 1.1e-19 gi|172048843|sp|A6NLJ0.1|NLF2_HUMAN RecName: Full= ( 364) 504 101.6 3.6e-19 gi|119598015|gb|EAW77609.1| nuclear localized fact ( 369) 498 100.5 7.8e-19 gi|74715236|sp|Q8NCU7.1|NLF1_HUMAN RecName: Full=N ( 369) 498 100.5 7.8e-19 gi|118095640|ref|XP_425063.2| PREDICTED: hypotheti ( 431) 496 100.2 1.1e-18 gi|114657351|ref|XP_523091.2| PREDICTED: nuclear l ( 369) 492 99.4 1.7e-18 gi|194035066|ref|XP_001924556.1| PREDICTED: simila ( 367) 491 99.2 1.9e-18 gi|114657423|ref|XP_001173423.1| PREDICTED: nuclea ( 363) 478 96.9 9.5e-18 gi|47225823|emb|CAF98303.1| unnamed protein produc ( 386) 450 91.8 3.3e-16 gi|126277287|ref|XP_001374439.1| PREDICTED: simila ( 406) 450 91.8 3.5e-16 gi|126631736|gb|AAI34040.1| Zgc:162595 protein [Da ( 457) 435 89.2 2.5e-15 gi|126313879|ref|XP_001372067.1| PREDICTED: simila ( 452) 433 88.8 3.2e-15 gi|187957312|gb|AAI57848.1| Unknown (protein for M ( 353) 383 79.7 1.4e-12 gi|126277290|ref|XP_001374460.1| PREDICTED: simila ( 441) 381 79.4 2.1e-12 gi|119889366|ref|XP_001254823.1| PREDICTED: simila ( 470) 379 79.0 2.8e-12 gi|109016665|ref|XP_001108285.1| PREDICTED: simila ( 353) 376 78.4 3.4e-12 gi|221039604|dbj|BAH11565.1| unnamed protein produ ( 353) 374 78.0 4.3e-12 gi|209870113|ref|NP_001129589.1| hypothetical prot ( 341) 367 76.7 1e-11 gi|194036206|ref|XP_001927719.1| PREDICTED: simila ( 563) 368 77.1 1.3e-11 gi|189536412|ref|XP_001919191.1| PREDICTED: simila ( 390) 331 70.3 1e-09 gi|194210802|ref|XP_001916080.1| PREDICTED: simila ( 779) 262 58.1 9.7e-06 gi|210084566|gb|EEA33084.1| hypothetical protein B ( 602) 254 56.5 2.2e-05 gi|149251621|ref|XP_195466.5| PREDICTED: hypotheti ( 322) 249 55.4 2.6e-05 gi|26348653|dbj|BAC37966.1| unnamed protein produc ( 222) 245 54.5 3.3e-05 gi|109484978|ref|XP_001056193.1| PREDICTED: simila ( 298) 221 50.3 0.00083 gi|74000841|ref|XP_535504.2| PREDICTED: similar to ( 215) 219 49.8 0.00084 gi|109483671|ref|XP_001079329.1| PREDICTED: simila ( 404) 221 50.4 0.001 gi|82930340|ref|XP_146937.4| PREDICTED: hypothetic ( 334) 216 49.4 0.0017 gi|94385775|ref|XP_001004252.1| PREDICTED: hypothe ( 340) 216 49.4 0.0017 gi|149028883|gb|EDL84224.1| rCG56585 [Rattus norve ( 176) 205 47.2 0.0042 gi|109483669|ref|XP_576426.2| PREDICTED: similar t ( 340) 205 47.4 0.0068 gi|47216747|emb|CAG03751.1| unnamed protein produc ( 302) 204 47.2 0.0071 >>gi|119581604|gb|EAW61200.1| hCG1659953, isoform CRA_c (613 aa) initn: 3068 init1: 3068 opt: 3084 Z-score: 3021.1 bits: 568.8 E(): 1.4e-159 Smith-Waterman score: 3084; 97.890% identity (98.523% similar) in 474 aa overlap (9-481:140-613) 10 20 30 KIAA19 VRLRCRRRRRP-HRSSGRVPRASPGSLRAETPACLRTD : : :.. : :.::::::::::::::: gi|119 WGLPRLPGGGGGEGENSSVSASLSDFGAASRLPQHKNEGSSTFAGPGSLRAETPACLRTD 110 120 130 140 150 160 40 50 60 70 80 90 KIAA19 LRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPL 170 180 190 200 210 220 100 110 120 130 140 150 KIAA19 YSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLA 230 240 250 260 270 280 160 170 180 190 200 210 KIAA19 AESKSLLKAATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AESKSLLKAATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESP 290 300 310 320 330 340 220 230 240 250 260 270 KIAA19 HTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 HTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESD 350 360 370 380 390 400 280 290 300 310 320 330 KIAA19 TGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSR 410 420 430 440 450 460 340 350 360 370 380 390 KIAA19 RRLTRRAPPEPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RRLTRRAPPEPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLC 470 480 490 500 510 520 400 410 420 430 440 450 KIAA19 DARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNK 530 540 550 560 570 580 460 470 480 KIAA19 GSSLKRDTLLGEKELPLTSLLPFL :::::::::::::::::::::::: gi|119 GSSLKRDTLLGEKELPLTSLLPFL 590 600 610 >>gi|21739976|emb|CAD39008.1| hypothetical protein [Homo (405 aa) initn: 2671 init1: 2671 opt: 2671 Z-score: 2619.5 bits: 493.8 E(): 3.3e-137 Smith-Waterman score: 2671; 100.000% identity (100.000% similar) in 405 aa overlap (77-481:1-405) 50 60 70 80 90 100 KIAA19 RRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDK :::::::::::::::::::::::::::::: gi|217 ENGAARGVGSEAGDKASKGPLYSNVLTPDK 10 20 30 110 120 130 140 150 160 KIAA19 IPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 IPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKA 40 50 60 70 80 90 170 180 190 200 210 220 KIAA19 ATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 ATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLF 100 110 120 130 140 150 230 240 250 260 270 280 KIAA19 HSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 HSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSP 160 170 180 190 200 210 290 300 310 320 330 340 KIAA19 FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPP 220 230 240 250 260 270 350 360 370 380 390 400 KIAA19 EPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 EPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCV 280 290 300 310 320 330 410 420 430 440 450 460 KIAA19 GLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 GLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTL 340 350 360 370 380 390 470 480 KIAA19 LGEKELPLTSLLPFL ::::::::::::::: gi|217 LGEKELPLTSLLPFL 400 >>gi|149034681|gb|EDL89418.1| rCG29198 [Rattus norvegicu (422 aa) initn: 1778 init1: 1778 opt: 2531 Z-score: 2482.3 bits: 468.5 E(): 1.5e-129 Smith-Waterman score: 2531; 90.521% identity (97.393% similar) in 422 aa overlap (61-481:1-422) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD ::::::::::::::::::::.::::.:::: gi|149 MRKTNMWFLERLRGSGENGASRGVGGEAGD 10 20 30 100 110 120 130 140 150 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSP :.:::::::::::::::::::::::::::: :.:::: :::::::::::: .::..:::: gi|149 KTSKGPLYSNVLTPDKIPDFFIPPKLPSGPPEAEGQADLGPSTSEQNLASPGPRRAPRSP 40 50 60 70 80 90 160 170 180 190 200 210 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGF :::.:::.::..:::::::::::::::::: .::::.::::::::::::::::::::::: gi|149 RLPVKLASESRNLLKAATRHVIQIESAEDWTAEEATNADPQAQGAMSLPSVPKAQTSYGF 100 110 120 130 140 150 220 230 240 250 260 270 KIAA19 AMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRY : :::::::::::::::::::::::::::::.::::.::::::::: ::.::.::::.:: gi|149 ATLAESPHTRRKESLFHSEHGALAQVGSPGASRRRAGAKANGGDGGSREVGGGLMSPSRY 160 170 180 190 200 210 280 290 300 310 320 330 KIAA19 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTP :::::::::::::::::::::::::::::::::::::::::::..::::::::::::::: gi|149 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKQSVGRHGSLSADDSTP 220 230 240 250 260 270 340 350 360 370 380 KIAA19 DASPGSRRRLTRRAPPEPGPESGQA-RGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAA :.::: :::::::: :::::::::: ::::::..: ::::::::::::.::::::.:::: gi|149 DTSPGVRRRLTRRATPEPGPESGQAPRGEHTVRMGTRGSVRLLAEYEAAQARLRVRLLAA 280 290 300 310 320 330 390 400 410 420 430 440 KIAA19 EGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLA :::::: ::::::::::::::::::::::::::.::::.:.::::::::::::::::::: gi|149 EGLYDRPCDARSINCCVGLCLVPGKLQKQRSTIIKNSRHPIFNEDFFFDGLGPASVRKLA 340 350 360 370 380 390 450 460 470 480 KIAA19 LRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL ::::::::::::::::::::.::::::::::: gi|149 LRIKVVNKGSSLKRDTLLGEEELPLTSLLPFL 400 410 420 >>gi|81889002|sp|Q5HZI2.1|NLF3_MOUSE RecName: Full=Nucle (419 aa) initn: 1626 init1: 1626 opt: 2518 Z-score: 2469.6 bits: 466.2 E(): 7.4e-129 Smith-Waterman score: 2518; 90.521% identity (96.919% similar) in 422 aa overlap (61-481:1-419) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD ::::::::::::::::::::.:: :::: gi|818 MRKTNMWFLERLRGSGENGASRG---EAGD 10 20 100 110 120 130 140 150 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSP :.::::::::::::::::::::::::::::.:.:::: :::::::::::: .::..:::: gi|818 KSSKGPLYSNVLTPDKIPDFFIPPKLPSGPTEAEGQADLGPSTSEQNLASPGPRRAPRSP 30 40 50 60 70 80 160 170 180 190 200 210 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGF :::::::.::.::::::::::::::::::: .::::.::::::::::::::::::::::: gi|818 RLPAKLASESRSLLKAATRHVIQIESAEDWTAEEATNADPQAQGAMSLPSVPKAQTSYGF 90 100 110 120 130 140 220 230 240 250 260 270 KIAA19 AMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRY : ::::::::::::::::::::::::::::::::::.::.:::::: ::.:::::::.:: gi|818 ATLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAGAKGNGGDGGSREVGGALMSPSRY 150 160 170 180 190 200 280 290 300 310 320 330 KIAA19 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTP :::::::::::::::::::::::::::::::::::::::::::..::::::::::::::: gi|818 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKQSVGRHGSLSADDSTP 210 220 230 240 250 260 340 350 360 370 380 KIAA19 DASPGSRRRLTRRAPPEPGPESGQA-RGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAA :.::: ::::.::: :::::::::: ::::::..: ::::::::::::.::::::.:::: gi|818 DTSPGVRRRLSRRATPEPGPESGQAPRGEHTVKMGTRGSVRLLAEYEAAQARLRVRLLAA 270 280 290 300 310 320 390 400 410 420 430 440 KIAA19 EGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLA :::::: ::::::::::::::::::::::::::.::::.:.::::::::::::::::::: gi|818 EGLYDRPCDARSINCCVGLCLVPGKLQKQRSTIIKNSRHPIFNEDFFFDGLGPASVRKLA 330 340 350 360 370 380 450 460 470 480 KIAA19 LRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL ::::::::::::::::::::.::::::::::: gi|818 LRIKVVNKGSSLKRDTLLGEEELPLTSLLPFL 390 400 410 >>gi|26325880|dbj|BAC26694.1| unnamed protein product [M (419 aa) initn: 1610 init1: 1610 opt: 2502 Z-score: 2453.9 bits: 463.3 E(): 5.5e-128 Smith-Waterman score: 2502; 90.047% identity (96.682% similar) in 422 aa overlap (61-481:1-419) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD ::::::::::::::::::::.:: :::: gi|263 MRKTNMWFLERLRGSGENGASRG---EAGD 10 20 100 110 120 130 140 150 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSP :.::::::::::::::::::::::::::::.:.:::: :::::::::::: .::..:::: gi|263 KSSKGPLYSNVLTPDKIPDFFIPPKLPSGPTEAEGQADLGPSTSEQNLASPGPRRAPRSP 30 40 50 60 70 80 160 170 180 190 200 210 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGF :::::::.::.::::::::::::::::::: ..:::.:::::::::::::: :::::::: gi|263 RLPAKLASESRSLLKAATRHVIQIESAEDWTADEATNADPQAQGAMSLPSVHKAQTSYGF 90 100 110 120 130 140 220 230 240 250 260 270 KIAA19 AMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRY : ::::::::::::::::::::::::::::::::::.::.:::::: ::.:::::::.:: gi|263 ATLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAGAKGNGGDGGSREVGGALMSPSRY 150 160 170 180 190 200 280 290 300 310 320 330 KIAA19 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTP :::::::::::::::::::::::::::::::::::::::::::..::::::::::::::: gi|263 FSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKQSVGRHGSLSADDSTP 210 220 230 240 250 260 340 350 360 370 380 KIAA19 DASPGSRRRLTRRAPPEPGPESGQA-RGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAA :.::: ::::.::: :::::::::: ::::::..: ::::::::::::.::::::.:::: gi|263 DTSPGVRRRLSRRATPEPGPESGQAPRGEHTVKMGTRGSVRLLAEYEAAQARLRVRLLAA 270 280 290 300 310 320 390 400 410 420 430 440 KIAA19 EGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLA :::::: ::::::::::::::::::::::::::.::::.:.::::::::::::::::::: gi|263 EGLYDRPCDARSINCCVGLCLVPGKLQKQRSTIIKNSRHPIFNEDFFFDGLGPASVRKLA 330 340 350 360 370 380 450 460 470 480 KIAA19 LRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL ::::::::::::::::::::.::::::::::: gi|263 LRIKVVNKGSSLKRDTLLGEEELPLTSLLPFL 390 400 410 >>gi|194668533|ref|XP_597854.4| PREDICTED: similar to RI (420 aa) initn: 1354 init1: 1019 opt: 2467 Z-score: 2419.7 bits: 456.9 E(): 4.5e-126 Smith-Waterman score: 2467; 89.598% identity (96.217% similar) in 423 aa overlap (61-481:1-420) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD :.:::::::::.::::::::: :.:.:: gi|194 MKKTNMWFLERFRGSGENGAA---GGEGGD 10 20 100 110 120 130 140 150 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSP ::.::::::::::::::::::::::::.:::: :.:: ::::::::::::::::..:::: gi|194 KAAKGPLYSNVLTPDKIPDFFIPPKLPAGPAEPEAQAELGPSTSEQNLASAAPRRAPRSP 30 40 50 60 70 80 160 170 180 190 200 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEE-ATDADPQAQGAMSLPSVPKAQTSYG :::::::::::::::::::::::::::::: .:: ::.:::::::::::::::::::::: gi|194 RLPAKLAAESKSLLKAATRHVIQIESAEDWPAEETATNADPQAQGAMSLPSVPKAQTSYG 90 100 110 120 130 140 210 220 230 240 250 260 KIAA19 FAMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGR :: ::::::::::::::::::::::::::::. :::...::::::::::::::.:::::: gi|194 FATLAESPHTRRKESLFHSEHGALAQVGSPGTRRRRGGVKANGGDGGPREAGGTLMSPGR 150 160 170 180 190 200 270 280 290 300 310 320 KIAA19 YFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDST ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: gi|194 CVSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKHSVGRHGSLSADDST 210 220 230 240 250 260 330 340 350 360 370 380 KIAA19 PDASPGSRRRLTRRAPPEPGPESGQA-RGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLA ::.:::.:::: ::: :::: ::: : :.::.:..::::::.:::::::.::::::.::: gi|194 PDTSPGARRRLHRRATPEPGRESGPASRAEHAVRMGPRGSVHLLAEYEAAQARLRVRLLA 270 280 290 300 310 320 390 400 410 420 430 440 KIAA19 AEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKL :::::::.:::::::::::::::::::::::::::::::.:::::::::::::::::::: gi|194 AEGLYDRMCDARSINCCVGLCLVPGKLQKQRSTIVKNSRHPVFNEDFFFDGLGPASVRKL 330 340 350 360 370 380 450 460 470 480 KIAA19 ALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL ::::::::::::::::::::::::::::::::: gi|194 ALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL 390 400 410 420 >>gi|73987619|ref|XP_542222.2| PREDICTED: similar to nuc (423 aa) initn: 1399 init1: 775 opt: 2388 Z-score: 2342.4 bits: 442.6 E(): 9e-122 Smith-Waterman score: 2388; 86.620% identity (95.305% similar) in 426 aa overlap (61-481:1-423) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD :::::::::::::::::.:. :::::: gi|739 MRKTNMWFLERLRGSGEHGTP---GSEAGD 10 20 100 110 120 130 140 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTS--EQNLASAAPRQTPR ::.::::::::::::::::::::::::.::...:::: ::... ::: ::. ::..:: gi|739 KAAKGPLYSNVLTPDKIPDFFIPPKLPAGPTDAEGQAEPGPAAAAAEQNPASGPPRRAPR 30 40 50 60 70 80 150 160 170 180 190 200 KIAA19 SPRLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEA-TDADPQAQGAMSLPSVPKAQTS :::::::::::::.:::::::::::::::::: ::: :.:::::::::::::::::::: gi|739 SPRLPAKLAAESKNLLKAATRHVIQIESAEDWPVEEAATNADPQAQGAMSLPSVPKAQTS 90 100 110 120 130 140 210 220 230 240 250 260 KIAA19 YGFAMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAA-KANGGDGGPREAGGALMS :::: :::::::::::::::::::::::::::::::::..: ::::::: ::::.::::: gi|739 YGFATLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRGGATKANGGDGVPREAAGALMS 150 160 170 180 190 200 270 280 290 300 310 320 KIAA19 PGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSAD :.:::::::::::::::::::::::::::::::::::::::::::::..:.::::::.:. gi|739 PSRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKQSAGRHGSLAAE 210 220 230 240 250 260 330 340 350 360 370 380 KIAA19 DSTPDASPGSRRRLTRRAPPEPGPESGQA-RGEHTVHVGPRGSVRLLAEYEAGQARLRVH :..::.:::.:::::::: ::::::.::. :.::.:.:::::::::::::::.::::::. gi|739 DGAPDTSPGARRRLTRRAAPEPGPETGQVPRAEHAVRVGPRGSVRLLAEYEAAQARLRVR 270 280 290 300 310 320 390 400 410 420 430 440 KIAA19 LLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASV ::::::::: :::::::::::::::::::::::::::.::::.::::::::::::::::: gi|739 LLAAEGLYDCLCDARSINCCVGLCLVPGKLQKQRSTIIKNSRHPVFNEDFFFDGLGPASV 330 340 350 360 370 380 450 460 470 480 KIAA19 RKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL :::::::::::::::::::::::::::::::::: : gi|739 RKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPSL 390 400 410 420 >>gi|126323770|ref|XP_001376103.1| PREDICTED: similar to (438 aa) initn: 1252 init1: 701 opt: 1708 Z-score: 1677.0 bits: 319.6 E(): 1e-84 Smith-Waterman score: 2002; 73.154% identity (84.116% similar) in 447 aa overlap (61-481:1-438) 40 50 60 70 80 90 KIAA19 PACLRTDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGD :.:::::.:.::::::::::.::. :: gi|126 MKKTNMWLLDRLRGSGENGASRGAD---GD 10 20 100 110 120 130 KIAA19 KASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAA----------------LGPSTS ..:::::::::::::::::::::::: .::.:.:: :: :: ::: gi|126 RSSKGPLYSNVLTPDKIPDFFIPPKLTTGPGEAEGAAAGSGSGSGSGSGSGSPHLGSSTS 30 40 50 60 70 80 140 150 160 170 180 KIAA19 EQNLAS--AAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDWLSEE-----ATD :::::: ..::.. ::::: ::::::::.:::::.:::::::::::: :: ::. gi|126 EQNLASGGSGPRKAQRSPRLTAKLAAESKNLLKAASRHVIQIESAEDWHPEEEEEAVATN 90 100 110 120 130 140 190 200 210 220 230 240 KIAA19 ADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAA :::::: ::::: ::::::::::: : :::::::::::::::: .:::.::::: :: gi|126 ADPQAQTAMSLPYVPKAQTSYGFATLMESPHTRRKESLFHSEHTGLAQAGSPGALRR--- 150 160 170 180 190 200 250 260 270 280 290 300 KIAA19 AKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQ ::::: .: : ::::: :::::::::::::::::::::::::::::::: ::::.: gi|126 AKANG-EGTSRAE--ALMSPYRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKVFAQDGQ 210 220 230 240 250 260 310 320 330 340 350 360 KIAA19 AKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEP---GPESGQARGEHTVHVG :::::::::::::.:::.:::. :.::..::: : .: : : :.. ::::::..: gi|126 AKVSQLRHSVGRHSSLSTDDSSADVSPSARRRARRATPTGPEASGDPSSSPRGEHTVRLG 270 280 290 300 310 320 370 380 390 400 410 420 KIAA19 PRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVK :::.:: :::. ..:::::.::::::::::: :.:::::::::::.:::::::::::.: gi|126 KRGSLRLAAEYDPARARLRVRLLAAEGLYDRLFDTRSINCCVGLCLTPGKLQKQRSTIIK 330 340 350 360 370 380 430 440 450 460 470 480 KIAA19 NSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL :. .:.:::::::::: :.:.:::::..::::::.::::::::::::.::: ::::: gi|126 NTWHPIFNEDFFFDGLCPSSARKLALKLKVVNKGGSLKRDTLLGEKEVPLTVLLPFL 390 400 410 420 430 >>gi|118103197|ref|XP_425894.2| PREDICTED: similar to RI (413 aa) initn: 1341 init1: 577 opt: 1646 Z-score: 1616.7 bits: 308.3 E(): 2.4e-81 Smith-Waterman score: 1646; 63.869% identity (80.420% similar) in 429 aa overlap (66-478:1-413) 40 50 60 70 80 90 KIAA19 TDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGDKASKG ::.:::::: .::..::: : : . .: gi|118 MWLLERLRGMAENSGARGSGP---DDSPRG 10 20 100 110 120 130 140 150 KIAA19 PLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAA-----LGPSTSEQNLASAAPRQTPRSP ::::::::::::::::::: ..:::.:: ::::.:::.:.. :.::::: gi|118 SRYSNVLTPDKIPDFFIPPKLSAAPAEAEGTEPTAPPILGPSVSEQDLTD---RKTPRSP 30 40 50 60 70 80 160 170 180 190 200 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEA--TDADPQAQGAMSLPSVPKAQTSY : :.. : ::. ::.::::::::: .: . :..::::: ::::: :::::::: gi|118 RPPSRPRA------KASGRHIIQIESAEDWTAEGGFGTNVDPQAQTAMSLPYVPKAQTSY 90 100 110 120 130 210 220 230 240 250 260 KIAA19 GFAMLAESPHTRRKESLFHSEHGAL--AQVGSPGAGRRRAAAKANGGD--GGPREAGGAL ::: :.::::::::::::::::..: . . ::.: :: :: :: . .: . :.:: gi|118 GFATLVESPHTRRKESLFHSEHSSLCPSPATSPSAQRR---AKLNGESRAQAPSDLGAAL 140 150 160 170 180 190 270 280 290 300 310 320 KIAA19 MSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLS : :::::::::::: ::::::::::::::::::::: :.:.::.:: .:.:::.:..::: gi|118 MHPGRYFSGGESDTCSSAESSPFGSPLLSRSVSLLKIFSQESQSKVIKLKHSVARNSSLS 200 210 220 230 240 250 330 340 350 360 370 KIAA19 ADDSTPDASPGSRRRLTRRAP----PEPGPESGQARG-EHTVHVGPRGSVRLLAEYEAGQ .:::. :.::...:: .: :: : : : :.: ::..... : .:: :.:. .. gi|118 TDDSSADTSPSAQRR-SRSAPAGGQPAAGTELPQGRPREHSLRLSRGGRLRLTADYDPSN 260 270 280 290 300 310 380 390 400 410 420 430 KIAA19 ARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDG :::::.:. :: ::: : :.:.:.:::.::: :::::::::::.:::: ::::::::::: gi|118 ARLRVQLICAEDLYDALVDVRGIHCCVSLCLNPGKLQKQRSTIIKNSRNPVFNEDFFFDG 320 330 340 350 360 370 440 450 460 470 480 KIAA19 LGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL :::. ::::.:..::::::::::::::::::::::..:: gi|118 LGPSHVRKLSLKLKVVNKGSSLKRDTLLGEKELPLSALL 380 390 400 410 >>gi|125865234|ref|XP_697197.2| PREDICTED: similar to Nu (421 aa) initn: 1207 init1: 518 opt: 1440 Z-score: 1415.1 bits: 271.0 E(): 4.1e-70 Smith-Waterman score: 1440; 55.944% identity (77.855% similar) in 429 aa overlap (66-478:1-418) 40 50 60 70 80 90 KIAA19 TDLRPRAITPGRRCSPCPGLLPAAPMRKTNMWFLERLRGSGENGAARGVGSEAGDKASKG ::.::..::: :... : ....:: ::. gi|125 MWLLEKIRGSVEGNVLRQ--GDSADKQSKA 10 20 100 110 120 130 140 150 KIAA19 PLYSNVLTPDKIPDFFIPPKLPSGPAEGEG-----QAALGPSTSEQNLASAAPRQTPRSP : ::::::::::::::::::: : : : . .: :::::.. .:. .:::: gi|125 PTYSNVLTPDKIPDFFIPPKLVCCPPEEETPEMKPKNGLHSSTSEQTICCKTPQGSPRSP 30 40 50 60 70 80 160 170 180 190 200 KIAA19 RLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEA----TDADPQAQGAMSLPSVPKAQT :: :::...:.:::::.::.::::::.: . .: :.::::.: ::::: :::::: gi|125 RLINKLAGDTKNLLKAANRHIIQIESADDLVVGDAGNLTTNADPQSQTAMSLPYVPKAQT 90 100 110 120 130 140 210 220 230 240 250 260 KIAA19 SYGFAMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMS ::::: : ::::::::::::::. . . ::.. : :..:. .: . . . . gi|125 SYGFATLMESPHTRRKESLFHSD--PTSPLTSPNTQR-----KSQGNHLNPSDCNTSHSN 150 160 170 180 190 200 270 280 290 300 310 320 KIAA19 PGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSAD : :::::::::: ::::::::.:::::::.:::: :....:::::. ..: .::.:::.: gi|125 PYRYFSGGESDTCSSAESSPFNSPLLSRSASLLKMFTHETQAKVSRAKRSFARHSSLSTD 210 220 230 240 250 260 330 340 350 360 370 KIAA19 D-STPDASPGSRRRLTRRAPPEPGPESGQARG------EHTVHVGPRGSVRLLAEYEAGQ . :. ..::. .::. : :: :. .. . : .:::.. :..:. ..:. gi|125 ECSSVETSPNIQRRF--RCPPSPAFRGRKYGGNMDRFTQHTVNLHKGGTLRICTDYDIDA 270 280 290 300 310 380 390 400 410 420 430 KIAA19 ARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDG :::....:::: :::. :::.::::::.: : :::::::::::.:::: :::::::.::. gi|125 ARLHIRVLAAEDLYDKQCDAKSINCCVSLYLNPGKLQKQRSTIIKNSRNPVFNEDFYFDS 320 330 340 350 360 370 440 450 460 470 480 KIAA19 LGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPFL : :.:..::...::::::.:::::.::::.:.:: :: gi|125 LPVAQVKNLAIKMKVVNKGTSLKRDNLLGEREVPLKELLSGI 380 390 400 410 420 481 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Fri Mar 6 05:52:01 2009 done: Fri Mar 6 05:56:14 2009 Total Scan time: 1530.310 Total Display time: 0.160 Function used was FASTA [version 34.26.5 April 26, 2007]