hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-15331336/chunk_1/iprscan-20080502-15331336.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1885 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00133.12.ls tRNA synthetases class I (I, L, M and V) 805.6 2.6e-239 1 PF00133.12.fs tRNA synthetases class I (I, L, M and V) 803.9 8.1e-239 1 PF08264.3.ls Anticodon-binding domain 132.1 1.5e-36 1 PF08264.3.fs Anticodon-binding domain 130.2 3e-36 1 PF09334.1.fs tRNA synthetases class I (M) 42.3 4e-13 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00133.12.ls 1/1 147 770 .. 1 724 [] 805.6 2.6e-239 PF00133.12.fs 1/1 147 770 .. 1 724 [] 803.9 8.1e-239 PF09334.1.fs 1/2 183 219 .. 10 48 .. 27.1 1.7e-08 PF09334.1.fs 2/2 691 708 .. 354 371 .. 15.1 8.2e-05 PF08264.3.ls 1/1 814 967 .. 1 176 [] 132.1 1.5e-36 PF08264.3.fs 1/1 814 967 .. 1 176 [] 130.2 3e-36 Alignments of top-scoring domains: PF00133.12.ls: domain 1 of 1, from 147 to 770: score 805.6, E = 2.6e-239 *->qiyefWdeqgyFkkslenrKgskps...FvlhDGPPnATGllHiGHA ++y +W +g+Fk++ +r + + ++++F+ ++PPn+TG+lHiGHA KIAA1885 147 AWYPWWVREGFFKPEYQARLP-QATgetFSMCIPPPNVTGSLHIGHA 192 LnktLKDiviRykrmqGfdvlwvpGwDhHGLPiElkVEkKLGikekkdrh L+ ++D ++R++rm G vlwvpG Dh+G++++++VEk+L+++++ rh KIAA1885 193 LTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLWKERGVRRH 242 klGrekFrekCrewkaeyadeirsqfkrLGvsvDwdreYfTLdpeleaav +l+re+F+ ++++wk+ ++ei +q + LG s+Dwdre fT+d + + av KIAA1885 243 ELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAV 292 wrvFveLhdkGLiYRGkKvVnWspklnTALSeaEVqQeYKDvk.RTLLdV ++Fv+L++ GL+YR + +VnWs +l++A+S++EV e++ + T L KIAA1885 293 TEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEV--ENRPLPgHTQLRL 340 PGYDkKVEFdpsihvaFplaDdakladgkgvkdvdspaslviWTTTPWTL PG V F+++ vaFp+ ++ ++ a v+ TT+P+TL KIAA1885 341 PGCPTPVSFGLLFSVAFPV------DGEPD-------AEVVVGTTRPETL 377 pgNtAvAVnPefnYvkvkDavtgellILAeaLleslykkkkeskyiIled pg++AvAV+P+ d KIAA1885 378 PGDVAVAVHPD--------------------------------------D 389 frgkeLegkkyihPFpYFlsdkldReipiiaddyVdmefGTGaVHiAPAH r+++L+g+ +hP+ ++ p i+d V GTGaV+ +PAH KIAA1885 390 SRYTHLHGRQLRHPL-------MGQPLPLITDYAVQPHVGTGAVKVTPAH 432 GedDYevGkkhnLIskddefinpvdddGtyneeaviTGraglypseilpe + D e G +h+L ++n++ +dGt++ + + KIAA1885 433 SPADAEMGARHGL-----SPLNVIAEDGTMTSLC-------------GDW 464 FqGlkrFkAdkkIvelLkEkGlLlkiekieHsYPhCWRsgtPiiyratpQ +qGl+rF A++kI L+E Gl+ + +++ P C Rsg++i+y ++ Q KIAA1885 465 LQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQ 514 WFVrmkeeklqGktLredalkavedGkvqfvPksigekrygnWleNiqDW WFVr +e + ++a kave G + P++ +k +W i DW KIAA1885 515 WFVRCQE-------MGARAAKAVESGALELSPSF-HQKNWQHWFSHIGDW 556 CISRQRwWGhPIPawy...skdtgEvyvreelkelvagreeeegeeawlh C+SRQ+wWGh+IPa++ ++ gE+ + +v+gr e e++e +++ KIAA1885 557 CVSRQLWWGHQIPAYLvveDHAQGEEDC------WVVGRSEAEAREVAAE 600 r..dakdlLTipSgkgagtLeqdeDVLDvWFdSGswpfsvlgwPftntke +++ ++ L tLe+d+DVLD+WF+S++ pfs lgwP + t++ KIAA1885 601 LtgRPGAEL---------TLERDPDVLDTWFSSALFPFSALGWPQE-TPD 640 fkkffPADmllEGsDQtRGWFysmivlgtaltGsaNGKPQVPYkevLvhG +++f+P ++l++GsD + +W+ +m +lgt ltG+ P+ vL h KIAA1885 641 LARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQL------PFSKVLLHP 684 lvrDeqGrKMSKSlGNvIdPldvidGIsLeDLhaKllggnlqpqeveKak vrD qGrKMSKSlGNv dP d+i+G++ L +Kl gnl+p e + ++ KIAA1885 685 MVRDRQGRKMSKSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVA 734 kaqkksFPnGIpkyGADALRlwLiassdygrDinfS<-* aqkk FP GIp++G+DALR++L++ +D+ +S KIAA1885 735 AAQKKDFPHGIPECGTDALRFTLCSHGVQAGDLHLS 770 PF00133.12.fs: domain 1 of 1, from 147 to 770: score 803.9, E = 8.1e-239 *->qiyefWdeqgyFkkslenrKgskps...FvlhDGPPnATGllHiGHA ++y +W +g+Fk++ +r + + ++++F+ ++PPn+TG+lHiGHA KIAA1885 147 AWYPWWVREGFFKPEYQARLP-QATgetFSMCIPPPNVTGSLHIGHA 192 LnktLKDiviRykrmqGfdvlwvpGwDhHGLPiElkVEkKLGikekkdrh L+ ++D ++R++rm G vlwvpG Dh+G++++++VEk+L+++++ rh KIAA1885 193 LTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLWKERGVRRH 242 klGrekFrekCrewkaeyadeirsqfkrLGvsvDwdreYfTLdpeleaav +l+re+F+ ++++wk+ ++ei +q + LG s+Dwdre fT+d + + av KIAA1885 243 ELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAV 292 wrvFveLhdkGLiYRGkKvVnWspklnTALSeaEVqQeYKDvk.RTLLdV ++Fv+L++ GL+YR + +VnWs +l++A+S++EV e++ + T L KIAA1885 293 TEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEV--ENRPLPgHTQLRL 340 PGYDkKVEFdpsihvaFplaDdakladgkgvkdvdspaslviWTTTPWTL PG V F+++ vaFp+ ++ ++ a v+ TT+P+TL KIAA1885 341 PGCPTPVSFGLLFSVAFPV------DGEPD-------AEVVVGTTRPETL 377 pgNtAvAVnPefnYvkvkDavtgellILAeaLleslykkkkeskyiIled pg++AvAV+P+ d KIAA1885 378 PGDVAVAVHPD--------------------------------------D 389 frgkeLegkkyihPFpYFlsdkldReipiiaddyVdmefGTGaVHiAPAH r+++L+g+ +hP+ ++ p i+d V GTGaV+ +PAH KIAA1885 390 SRYTHLHGRQLRHPL-------MGQPLPLITDYAVQPHVGTGAVKVTPAH 432 GedDYevGkkhnLIskddefinpvdddGtyneeaviTGraglypseilpe + D e G +h+L ++n++ +dGt++ + + KIAA1885 433 SPADAEMGARHGL-----SPLNVIAEDGTMTSLC-------------GDW 464 FqGlkrFkAdkkIvelLkEkGlLlkiekieHsYPhCWRsgtPiiyratpQ +qGl+rF A++kI L+E Gl+ + +++ P C Rsg++i+y ++ Q KIAA1885 465 LQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQ 514 WFVrmkeeklqGktLredalkavedGkvqfvPksigekrygnWleNiqDW WFVr +e + ++a kave G + P++ +k +W i DW KIAA1885 515 WFVRCQE-------MGARAAKAVESGALELSPSF-HQKNWQHWFSHIGDW 556 CISRQRwWGhPIPawy...skdtgEvyvreelkelvagreeeegeeawlh C+SRQ+wWGh+IPa++ ++ gE+ + +v+gr e e++e +++ KIAA1885 557 CVSRQLWWGHQIPAYLvveDHAQGEEDC------WVVGRSEAEAREVAAE 600 r..dakdlLTipSgkgagtLeqdeDVLDvWFdSGswpfsvlgwPftntke +++ ++ L tLe+d+DVLD+WF+S++ pfs lgwP + t++ KIAA1885 601 LtgRPGAEL---------TLERDPDVLDTWFSSALFPFSALGWPQE-TPD 640 fkkffPADmllEGsDQtRGWFysmivlgtaltGsaNGKPQVPYkevLvhG +++f+P ++l++GsD + +W+ +m +lgt ltG+ P+ vL h KIAA1885 641 LARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQL------PFSKVLLHP 684 lvrDeqGrKMSKSlGNvIdPldvidGIsLeDLhaKllggnlqpqeveKak vrD qGrKMSKSlGNv dP d+i+G++ L +Kl gnl+p e + ++ KIAA1885 685 MVRDRQGRKMSKSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVA 734 kaqkksFPnGIpkyGADALRlwLiassdygrDinfS<-* aqkk FP GIp++G+DALR++L++ +D+ +S KIAA1885 735 AAQKKDFPHGIPECGTDALRFTLCSHGVQAGDLHLS 770 PF09334.1.fs: domain 1 of 2, from 183 to 219: score 27.1, E = 1.7e-08 *->vNGppHiGHlyGttipADvyaRYkRLrYGydVlFvtGTD<-* v G++HiGH++ t+ + D+++R++R+r G++Vl v G+D KIAA1885 183 VTGSLHIGHAL-TVAIQDALVRWHRMR-GDQVLWVPGSD 219 PF09334.1.fs: domain 2 of 2, from 691 to 708: score 15.1, E = 8.2e-05 *->GgKMSKSrGnvVdpdell<-* G+KMSKS+Gnv dp +++ KIAA1885 691 GRKMSKSLGNVLDPRDII 708 PF08264.3.ls: domain 1 of 1, from 814 to 967: score 132.1, E = 1.5e-36 *->DrWiLsrLnelikevteayenYdFnkAaralyeFiwndlcdwYlels D WiLsrL+ +++e + + +++ +++al++F+ + lcd+Yle + KIAA1885 814 DAWILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAV 860 KdrlygeeeegeGsaadddks......eapakraAqttLyevLeallrLL K++l+ +s+++ ++++ +L+ + + lrLL KIAA1885 861 KPVLW--------------HSprplgpPQ--------VLFSCADLGLRLL 888 aPfmPFitEEiWqrLpg.....eeeSvhladwPvdelevdgfdeake.we aP mPF++EE+WqrLp++++ +++ S+ +a++P a + + KIAA1885 889 APLMPFLAEELWQRLPPrpgcpPAPSISVAPYP----------SACSlEH 928 lidlekleaemellkevikaiRslRaeknikpslplkvliv<-* ++ ++le+++ ++ev+ +R+lRa + + +++ +vl+ KIAA1885 929 WRQ-PELERRFSRVQEVVQVLRALRATYQL-TKARPRVLLQ 967 PF08264.3.fs: domain 1 of 1, from 814 to 967: score 130.2, E = 3e-36 *->DrWiLsrLnelikevteayenYdFnkAaralyeFiwndlcdwYlels D WiLsrL+ +++e + + +++ +++al++F+ + lcd+Yle + KIAA1885 814 DAWILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAV 860 KdrlygeeeegeGsaadddks......eapakraAqttLyevLeallrLL K++l+ +s+++ ++++ +L+ + + lrLL KIAA1885 861 KPVLW--------------HSprplgpPQ--------VLFSCADLGLRLL 888 aPfmPFitEEiWqrLpg.....eeeSvhladwPvdelevdgfdeake.we aP mPF++EE+WqrLp++++ +++ S+ +a++P a + + KIAA1885 889 APLMPFLAEELWQRLPPrpgcpPAPSISVAPYP----------SACSlEH 928 lidlekleaemellkevikaiRslRaeknikpslplkvliv<-* ++ ++le+++ ++ev+ +R+lRa + + +++ +vl+ KIAA1885 929 WRQ-PELERRFSRVQEVVQVLRALRATYQL-TKARPRVLLQ 967 //