# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/fh21239.fasta.nr -Q ../query/KIAA1551.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1551, 1249 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7824585 sequences Expectation_n fit: rho(ln(x))= 6.0849+/-0.000193; mu= 9.9293+/- 0.011 mean_var=103.8069+/-19.711, 0's: 36 Z-trim: 44 B-trim: 144 in 1/67 Lambda= 0.125881 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 40, opt: 28, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|119608944|gb|EAW88538.1| chromosome 12 open rea (1747) 8005 1465.6 0 gi|156630979|sp|Q9HCM1.2|CL035_HUMAN RecName: Full (1747) 8003 1465.2 0 gi|119608943|gb|EAW88537.1| chromosome 12 open rea (1580) 7998 1464.3 0 gi|187954969|gb|AAI40820.1| Chromosome 12 open rea (1747) 7989 1462.7 0 gi|109096099|ref|XP_001084139.1| PREDICTED: simila (1668) 7445 1363.9 0 gi|109096095|ref|XP_001084251.1| PREDICTED: simila (1745) 7445 1363.9 0 gi|7020957|dbj|BAA91330.1| unnamed protein product ( 993) 6411 1175.9 0 gi|194211820|ref|XP_001503163.2| PREDICTED: simila (1756) 4761 876.5 0 gi|11611577|dbj|BAB19003.1| hypothetical protein [ ( 762) 4579 843.1 0 gi|15208227|dbj|BAB63138.1| hypothetical protein [ ( 709) 3120 578.2 6.3e-162 gi|157279076|gb|AAI53278.1| LOC510651 protein [Bos (1661) 3001 556.8 3.9e-155 gi|154426096|gb|AAI51613.1| LOC510651 protein [Bos (1741) 3001 556.8 4e-155 gi|73997206|ref|XP_534845.2| PREDICTED: similar to (1739) 2976 552.3 9.4e-154 gi|26327797|dbj|BAC27639.1| unnamed protein produc (1020) 1096 210.7 3.7e-51 gi|148678820|gb|EDL10767.1| RIKEN cDNA 2810474O19, (1177) 1096 210.7 4.2e-51 gi|148678819|gb|EDL10766.1| RIKEN cDNA 2810474O19, (1445) 1096 210.8 4.9e-51 gi|156630980|sp|Q5DTW7.2|CL035_MOUSE RecName: Full (1521) 1096 210.8 5.1e-51 gi|149048910|gb|EDM01364.1| rCG29614 [Rattus norve (1432) 753 148.5 2.7e-32 gi|109472857|ref|XP_229579.4| PREDICTED: hypotheti (1509) 753 148.5 2.8e-32 gi|74198717|dbj|BAC27553.2| unnamed protein produc ( 405) 602 120.7 1.9e-24 gi|12850749|dbj|BAB28838.1| unnamed protein produc ( 362) 385 81.2 1.3e-12 gi|60544838|gb|AAX22757.1| gonad expressed transcr (1593) 320 69.9 1.4e-08 gi|118082943|ref|XP_416367.2| PREDICTED: similar t (1603) 295 65.4 3.3e-07 gi|221110189|ref|XP_002168424.1| PREDICTED: hypoth (1954) 292 64.9 5.5e-07 gi|70833424|gb|EAN78928.1| hypothetical protein, c (3452) 283 63.5 2.7e-06 gi|89298365|gb|EAR96353.1| hypothetical protein TT (3274) 270 61.1 1.3e-05 gi|12856585|dbj|BAB30717.1| unnamed protein produc ( 307) 255 57.6 1.4e-05 gi|89303110|gb|EAS01098.1| hypothetical protein TT (3459) 262 59.6 3.7e-05 gi|89301141|gb|EAR99129.1| hypothetical protein TT (6052) 264 60.2 4.5e-05 gi|89302359|gb|EAS00347.1| Protein kinase domain c (1896) 254 58.0 6.5e-05 gi|46444373|gb|EAL03648.1| potential cell surface (1409) 236 54.6 0.0005 gi|27370948|gb|AAH38922.1| 2810474O19Rik protein [ ( 230) 221 51.3 0.00082 gi|89299494|gb|EAR97482.1| hypothetical protein TT (1918) 229 53.5 0.0015 gi|12724625|gb|AAK05715.1|AE006392_1 UNKNOWN PROTE (1072) 225 52.5 0.0016 gi|121904759|gb|EAY09700.1| hypothetical protein T (3352) 230 53.8 0.0021 gi|194218864|ref|XP_001916050.1| PREDICTED: simila (1104) 222 52.0 0.0024 gi|60467767|gb|EAL65783.1| RabGAP/TBC domain-conta (1455) 220 51.7 0.0038 gi|116102027|gb|ABJ67170.1| Subtilisin-like serine (2334) 222 52.3 0.0043 gi|121900432|gb|EAY05469.1| viral A-type inclusion (1297) 217 51.1 0.0051 gi|190619551|gb|EDV35075.1| GF22558 [Drosophila an (1299) 216 51.0 0.0058 gi|115695762|ref|XP_001201322.1| PREDICTED: hypoth ( 959) 213 50.3 0.0067 gi|114188137|gb|EAU29837.1| predicted protein [Asp (3451) 219 51.8 0.0084 gi|89307116|gb|EAS05104.1| hypothetical protein TT (1311) 213 50.4 0.0085 >>gi|119608944|gb|EAW88538.1| chromosome 12 open reading (1747 aa) initn: 8111 init1: 8005 opt: 8005 Z-score: 7852.5 bits: 1465.6 E(): 0 Smith-Waterman score: 8005; 99.675% identity (99.837% similar) in 1230 aa overlap (1-1230:167-1396) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::::::::::::::::::::::::::: gi|119 SHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: gi|119 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT 680 690 700 710 720 730 580 590 600 610 620 630 KIAA15 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS 740 750 760 770 780 790 640 650 660 670 680 690 KIAA15 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ 800 810 820 830 840 850 700 710 720 730 740 750 KIAA15 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL 860 870 880 890 900 910 760 770 780 790 800 810 KIAA15 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE 920 930 940 950 960 970 820 830 840 850 860 870 KIAA15 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP 980 990 1000 1010 1020 1030 880 890 900 910 920 930 KIAA15 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 KIAA15 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 KIAA15 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: gi|119 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCCPLDTNSCK 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 1110 KIAA15 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA 1220 1230 1240 1250 1260 1270 1120 1130 1140 1150 1160 1170 KIAA15 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT 1280 1290 1300 1310 1320 1330 1180 1190 1200 1210 1220 1230 KIAA15 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDTQD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :. gi|119 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQE 1340 1350 1360 1370 1380 1390 1240 KIAA15 AEKNDLASKGHSPHPQRLK gi|119 QKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHK 1400 1410 1420 1430 1440 1450 >>gi|156630979|sp|Q9HCM1.2|CL035_HUMAN RecName: Full=Unc (1747 aa) initn: 8109 init1: 8003 opt: 8003 Z-score: 7850.6 bits: 1465.2 E(): 0 Smith-Waterman score: 8003; 99.675% identity (99.919% similar) in 1230 aa overlap (1-1230:167-1396) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::::::::::::::::::::::::::: gi|156 SHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: gi|156 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: gi|156 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDGVQTLAQTNEEKIMDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT 680 690 700 710 720 730 580 590 600 610 620 630 KIAA15 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS 740 750 760 770 780 790 640 650 660 670 680 690 KIAA15 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ 800 810 820 830 840 850 700 710 720 730 740 750 KIAA15 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL 860 870 880 890 900 910 760 770 780 790 800 810 KIAA15 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE 920 930 940 950 960 970 820 830 840 850 860 870 KIAA15 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP 980 990 1000 1010 1020 1030 880 890 900 910 920 930 KIAA15 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 KIAA15 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 KIAA15 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 1110 KIAA15 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA 1220 1230 1240 1250 1260 1270 1120 1130 1140 1150 1160 1170 KIAA15 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|156 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT 1280 1290 1300 1310 1320 1330 1180 1190 1200 1210 1220 1230 KIAA15 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDTQD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :. gi|156 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQE 1340 1350 1360 1370 1380 1390 1240 KIAA15 AEKNDLASKGHSPHPQRLK gi|156 QKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHK 1400 1410 1420 1430 1440 1450 >>gi|119608943|gb|EAW88537.1| chromosome 12 open reading (1580 aa) initn: 8104 init1: 7998 opt: 7998 Z-score: 7846.2 bits: 1464.3 E(): 0 Smith-Waterman score: 7998; 99.675% identity (99.837% similar) in 1229 aa overlap (2-1230:1-1229) 10 20 30 40 50 60 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 MIPSNSTRLPVAYQGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFL 10 20 30 40 50 70 80 90 100 110 120 KIAA15 PDSTIQKQNFIPHTSLQVKNSQLPNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PDSTIQKQNFIPHTSLQVKNSQLPNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRY 60 70 80 90 100 110 130 140 150 160 170 180 KIAA15 GSQPLQSTQHITKHLSMEVPQSQEMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNS ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: gi|119 GSQPLQSTQHITKHLSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNS 120 130 140 150 160 170 190 200 210 220 230 240 KIAA15 KQPFNGPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KQPFNGPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQK 180 190 200 210 220 230 250 260 270 280 290 300 KIAA15 FSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAE 240 250 260 270 280 290 310 320 330 340 350 360 KIAA15 RQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLT 300 310 320 330 340 350 370 380 390 400 410 420 KIAA15 SKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLA 360 370 380 390 400 410 430 440 450 460 470 480 KIAA15 LLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLD 420 430 440 450 460 470 490 500 510 520 530 540 KIAA15 NSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGIS 480 490 500 510 520 530 550 560 570 580 590 600 KIAA15 KPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPL 540 550 560 570 580 590 610 620 630 640 650 660 KIAA15 VLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTA 600 610 620 630 640 650 670 680 690 700 710 720 KIAA15 TSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVS 660 670 680 690 700 710 730 740 750 760 770 780 KIAA15 SDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNT 720 730 740 750 760 770 790 800 810 820 830 840 KIAA15 TENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKST 780 790 800 810 820 830 850 860 870 880 890 900 KIAA15 ANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGI 840 850 860 870 880 890 910 920 930 940 950 960 KIAA15 EAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPY 900 910 920 930 940 950 970 980 990 1000 1010 1020 KIAA15 VVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVP 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 KIAA15 QCQCNSIKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKS ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: gi|119 QCQCNSIKNSSSEEEKQKEQCCPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKS 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 KIAA15 HFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 HFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHS 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 KIAA15 SNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKL 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 KIAA15 KSVSFKQKRKLDQGNVLDMEVKKKKHDTQDAEKNDLASKGHSPHPQRLK ::::::::::::::::::::::::::: :. gi|119 KSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVS 1200 1210 1220 1230 1240 1250 >>gi|187954969|gb|AAI40820.1| Chromosome 12 open reading (1747 aa) initn: 8121 init1: 7989 opt: 7989 Z-score: 7836.8 bits: 1462.7 E(): 0 Smith-Waterman score: 7989; 99.593% identity (99.837% similar) in 1230 aa overlap (1-1230:167-1396) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::::::::::::::::::::::::::: gi|187 SHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: gi|187 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLLNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: gi|187 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: gi|187 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDGVQTLAQTNEEKIMDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT 680 690 700 710 720 730 580 590 600 610 620 630 KIAA15 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS 740 750 760 770 780 790 640 650 660 670 680 690 KIAA15 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ 800 810 820 830 840 850 700 710 720 730 740 750 KIAA15 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL 860 870 880 890 900 910 760 770 780 790 800 810 KIAA15 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE 920 930 940 950 960 970 820 830 840 850 860 870 KIAA15 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP 980 990 1000 1010 1020 1030 880 890 900 910 920 930 KIAA15 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 KIAA15 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 KIAA15 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 1110 KIAA15 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 QGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVA 1220 1230 1240 1250 1260 1270 1120 1130 1140 1150 1160 1170 KIAA15 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 GQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKT 1280 1290 1300 1310 1320 1330 1180 1190 1200 1210 1220 1230 KIAA15 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDTQD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :. gi|187 KTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQE 1340 1350 1360 1370 1380 1390 1240 KIAA15 AEKNDLASKGHSPHPQRLK gi|187 QKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHK 1400 1410 1420 1430 1440 1450 >>gi|109096099|ref|XP_001084139.1| PREDICTED: similar to (1668 aa) initn: 4367 init1: 3079 opt: 7445 Z-score: 7303.2 bits: 1363.9 E(): 0 Smith-Waterman score: 7445; 92.052% identity (97.486% similar) in 1233 aa overlap (1-1230:167-1393) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::: ::::..::::::::::::::::: gi|109 SHQTDFGTNAPNMPALQSQLVTSDTYSMQMQMIPSNPTRLPAVYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :::::::::::::::::::::::::::::: :::::::::.:.::::::::::::::::: gi|109 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLQDSTIQKQNFMPRTSLQVKNSQLPNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::.::.:::::::::::::::::::::::: :::::::::.:::::::::::.::::::: gi|109 PSKQTAAVPSQQYATQTDKRPPPPPYNCRYISQPLQSTQHVTKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC ::::::::::::::::::::::::::::.:::: : ::::::::.::::::::::: ::: gi|109 RTSFQQQWQNPNENVSTIGNFTNLKVNTSSKQPVNDPIRSSVDGIQTLAQTNEEKITDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE ::::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::. gi|109 NPTSNQVLDTNVTKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSK 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::.::::::.:::::::.::::::::::: ::::::.::::::::.::::::::::: gi|109 PAQNSQLSLKQTTKIQSGPQVTPVMPENAERQQPTVVESTETNKTQCMMNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::.::::::::::::::::::::.::::::::::.:::::::::::::: gi|109 FNQVDSVLPNPVYTEKRPMPDPSHDVKVLTSKTSTVEMTQAVLNTRLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::.:::::::::::::::::::::::.:::::::::::::::::: ::::: gi|109 AVCETISVPKSISTEEYKSKIQNENMLLLALLSQAHKTQKTVLKDANQTIQDSKLDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC ::::::::::::::.:::::::::::.::::::::::::::::::::::: ::::::::: gi|109 NPNTQMTGNQLNLKTMETPSTSNVSGKVLDNSFCSGQESSTKGMPAKSDS-CSMEVLATC 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT :::::::::.:.:::.:::::::::.::::::::::.::::::::::::::::::::::: gi|109 LSLWKKQPSETTKEKQCDKLRTNTTVVGISKPANIHIKSPCSVVGNSNSQNKISNPSQQT 680 690 700 710 720 730 580 590 600 610 620 630 KIAA15 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS :::::.::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|109 ALSMVVHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAALPETVYPVIKEGS 740 750 760 770 780 790 640 650 660 670 680 690 KIAA15 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ ::::::::::::::.:::::::::::::::::::::::::::::::::.::::::::::: gi|109 VCSLQNQLAENAKAAAALKVDVSGPVASTATSTKIFPLTQKEKQNESTHGNSEVTPNVNQ 800 810 820 830 840 850 700 710 720 730 740 750 KIAA15 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL :::::::::.:::::::: ::::::::.:::: ::::::::::::::::::::::::::: gi|109 GKHNKLESAMHSPMNDQQTSQESRNSTIVSSDILQIDNICSLVEGDTSYNSQIAKIFSSL 860 870 880 890 900 910 760 770 780 790 800 810 KIAA15 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE :::::::::::.::::: ::::::::::::.::::::::::::::::::::::::::: : gi|109 PLKMVEPQKPSVPNQQGNGSREPEKQLDNTAENKDFGFQKDKPVQCTDVSHKICDQSKLE 920 930 940 950 960 970 820 830 840 850 860 870 KIAA15 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP :::::: :.::::: ::::::. ::::::::::::: ::::::::::::::::::::::: gi|109 PPLESSCNDLETNRGILEKSSVGHATEKSTANDTCSLAAIQEDIYPQEIDASSNYTPQDP 980 990 1000 1010 1020 1030 880 890 900 910 920 930 KIAA15 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD ::::::.::::::::::::::::::::::::::::::.::::::.::::::::::::::: gi|109 ARNEIHNDKAPVLYLHDQLSELLKEFPYGIEAVNTRESSVGQQTAYQTSEDQTADKTSSD 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 KIAA15 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ :::::::::::.::::::::::::::::::::: :.::::.:::::::.: :::.:. gi|109 SKDPADQIQITVLSSEQMKEIFPEQDDQPYVVDDLTEPQKDEPITEVVTQ----APAGGE 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 KIAA15 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK :::::.::::::::::::::::::::::::::::::::::.::::::::::: :.::::: gi|109 SRDSVVLDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSTSEEEKQKEQCS-LETNSCK 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 KIAA15 QGERTSDRDVTVVQFKSLVNNPKTPP---DGKSHFPELQDDSRKDTPKTKHKSLPRTEQE :::::::::::::::::::::::::: :::::::::::..::.: ::::::::::::: gi|109 QGERTSDRDVTVVQFKSLVNNPKTPPTSPDGKSHFPELQDNNRKETSKTKHKSLPRTEQE 1220 1230 1240 1250 1260 1270 1110 1120 1130 1140 1150 1160 KIAA15 LVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRP :.::.::::::::.::::::.: ::::::::::::::::::::::::::::::.:::::: gi|109 LTAGEFSSKCDKLDPLQNHKKKPLRFHEVTFHSSNKMTASYEQASQETRQKKHITQNSRP 1280 1290 1300 1310 1320 1330 1170 1180 1190 1200 1210 1220 KIAA15 LKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHD ::.::.::::::.:::::::::: ::::.:::.:::::.:::::::::::: :::::::: gi|109 LKAKTTFLPNKDLYKKHSSLGQSSSPEKVKLKFKSVSFRQKRKLDQGNVLDTEVKKKKHD 1340 1350 1360 1370 1380 1390 1230 1240 KIAA15 TQDAEKNDLASKGHSPHPQRLK :. gi|109 KQEQKGSVGATFKLGDSLSNPNERAIVKEKIVSNTKSVDTKASSSKFSRILTPKEYLQRQ 1400 1410 1420 1430 1440 1450 >>gi|109096095|ref|XP_001084251.1| PREDICTED: similar to (1745 aa) initn: 4367 init1: 3079 opt: 7445 Z-score: 7302.9 bits: 1363.9 E(): 0 Smith-Waterman score: 7445; 92.052% identity (97.486% similar) in 1233 aa overlap (1-1230:167-1393) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::: ::::..::::::::::::::::: gi|109 SHQTDFGTNAPNMPALQSQLVTSDTYSMQMQMIPSNPTRLPAVYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :::::::::::::::::::::::::::::: :::::::::.:.::::::::::::::::: gi|109 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLQDSTIQKQNFMPRTSLQVKNSQLPNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::.::.:::::::::::::::::::::::: :::::::::.:::::::::::.::::::: gi|109 PSKQTAAVPSQQYATQTDKRPPPPPYNCRYISQPLQSTQHVTKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC ::::::::::::::::::::::::::::.:::: : ::::::::.::::::::::: ::: gi|109 RTSFQQQWQNPNENVSTIGNFTNLKVNTSSKQPVNDPIRSSVDGIQTLAQTNEEKITDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE ::::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::. gi|109 NPTSNQVLDTNVTKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSK 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::.::::::.:::::::.::::::::::: ::::::.::::::::.::::::::::: gi|109 PAQNSQLSLKQTTKIQSGPQVTPVMPENAERQQPTVVESTETNKTQCMMNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::.::::::::::::::::::::.::::::::::.:::::::::::::: gi|109 FNQVDSVLPNPVYTEKRPMPDPSHDVKVLTSKTSTVEMTQAVLNTRLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::.:::::::::::::::::::::::.:::::::::::::::::: ::::: gi|109 AVCETISVPKSISTEEYKSKIQNENMLLLALLSQAHKTQKTVLKDANQTIQDSKLDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC ::::::::::::::.:::::::::::.::::::::::::::::::::::: ::::::::: gi|109 NPNTQMTGNQLNLKTMETPSTSNVSGKVLDNSFCSGQESSTKGMPAKSDS-CSMEVLATC 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT :::::::::.:.:::.:::::::::.::::::::::.::::::::::::::::::::::: gi|109 LSLWKKQPSETTKEKQCDKLRTNTTVVGISKPANIHIKSPCSVVGNSNSQNKISNPSQQT 680 690 700 710 720 730 580 590 600 610 620 630 KIAA15 ALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGS :::::.::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|109 ALSMVVHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAALPETVYPVIKEGS 740 750 760 770 780 790 640 650 660 670 680 690 KIAA15 VCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQ ::::::::::::::.:::::::::::::::::::::::::::::::::.::::::::::: gi|109 VCSLQNQLAENAKAAAALKVDVSGPVASTATSTKIFPLTQKEKQNESTHGNSEVTPNVNQ 800 810 820 830 840 850 700 710 720 730 740 750 KIAA15 GKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSL :::::::::.:::::::: ::::::::.:::: ::::::::::::::::::::::::::: gi|109 GKHNKLESAMHSPMNDQQTSQESRNSTIVSSDILQIDNICSLVEGDTSYNSQIAKIFSSL 860 870 880 890 900 910 760 770 780 790 800 810 KIAA15 PLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSE :::::::::::.::::: ::::::::::::.::::::::::::::::::::::::::: : gi|109 PLKMVEPQKPSVPNQQGNGSREPEKQLDNTAENKDFGFQKDKPVQCTDVSHKICDQSKLE 920 930 940 950 960 970 820 830 840 850 860 870 KIAA15 PPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDP :::::: :.::::: ::::::. ::::::::::::: ::::::::::::::::::::::: gi|109 PPLESSCNDLETNRGILEKSSVGHATEKSTANDTCSLAAIQEDIYPQEIDASSNYTPQDP 980 990 1000 1010 1020 1030 880 890 900 910 920 930 KIAA15 ARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSD ::::::.::::::::::::::::::::::::::::::.::::::.::::::::::::::: gi|109 ARNEIHNDKAPVLYLHDQLSELLKEFPYGIEAVNTRESSVGQQTAYQTSEDQTADKTSSD 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 KIAA15 SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQ :::::::::::.::::::::::::::::::::: :.::::.:::::::.: :::.:. gi|109 SKDPADQIQITVLSSEQMKEIFPEQDDQPYVVDDLTEPQKDEPITEVVTQ----APAGGE 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 KIAA15 SRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCK :::::.::::::::::::::::::::::::::::::::::.::::::::::: :.::::: gi|109 SRDSVVLDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSTSEEEKQKEQCS-LETNSCK 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 KIAA15 QGERTSDRDVTVVQFKSLVNNPKTPP---DGKSHFPELQDDSRKDTPKTKHKSLPRTEQE :::::::::::::::::::::::::: :::::::::::..::.: ::::::::::::: gi|109 QGERTSDRDVTVVQFKSLVNNPKTPPTSPDGKSHFPELQDNNRKETSKTKHKSLPRTEQE 1220 1230 1240 1250 1260 1270 1110 1120 1130 1140 1150 1160 KIAA15 LVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRP :.::.::::::::.::::::.: ::::::::::::::::::::::::::::::.:::::: gi|109 LTAGEFSSKCDKLDPLQNHKKKPLRFHEVTFHSSNKMTASYEQASQETRQKKHITQNSRP 1280 1290 1300 1310 1320 1330 1170 1180 1190 1200 1210 1220 KIAA15 LKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHD ::.::.::::::.:::::::::: ::::.:::.:::::.:::::::::::: :::::::: gi|109 LKAKTTFLPNKDLYKKHSSLGQSSSPEKVKLKFKSVSFRQKRKLDQGNVLDTEVKKKKHD 1340 1350 1360 1370 1380 1390 1230 1240 KIAA15 TQDAEKNDLASKGHSPHPQRLK :. gi|109 KQEQKGSVGATFKLGDSLSNPNERAIVKEKIVSNTKSVDTKASSSKFSRILTPKEYLQRQ 1400 1410 1420 1430 1440 1450 >>gi|7020957|dbj|BAA91330.1| unnamed protein product [Ho (993 aa) initn: 6454 init1: 6411 opt: 6411 Z-score: 6291.4 bits: 1175.9 E(): 0 Smith-Waterman score: 6411; 99.597% identity (99.799% similar) in 993 aa overlap (137-1129:1-993) 110 120 130 140 150 160 KIAA15 TDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEIRTSFQQQWQNPNENVS ::::::.::::::::::::::::::::::: gi|702 MEVPQSREMLSSEIRTSFQQQWQNPNENVS 10 20 30 170 180 190 200 210 220 KIAA15 TIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 TIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEK 40 50 60 70 80 90 230 240 250 260 270 280 KIAA15 LVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 LVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQ 100 110 120 130 140 150 290 300 310 320 330 340 KIAA15 SGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 SGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEK 160 170 180 190 200 210 350 360 370 380 390 400 KIAA15 RPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 RPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEE 220 230 240 250 260 270 410 420 430 440 450 460 KIAA15 YKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 YKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNM 280 290 300 310 320 330 470 480 490 500 510 520 KIAA15 ETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 ETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKE 340 350 360 370 380 390 530 540 550 560 570 580 KIAA15 CDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 CDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINI 400 410 420 430 440 450 590 600 610 620 630 640 KIAA15 TKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 TKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATA 460 470 480 490 500 510 650 660 670 680 690 700 KIAA15 ALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 ALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMND 520 530 540 550 560 570 710 720 730 740 750 760 KIAA15 QQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 QQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQ 580 590 600 610 620 630 770 780 790 800 810 820 KIAA15 GIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 GIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVI 640 650 660 670 680 690 830 840 850 860 870 880 KIAA15 LEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 LEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLH 700 710 720 730 740 750 890 900 910 920 930 940 KIAA15 DQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 DQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSE 760 770 780 790 800 810 950 960 970 980 990 1000 KIAA15 QMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHC ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: gi|702 QMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQALAAGQSRDSVILDSEKDDIHC 820 830 840 850 860 870 1010 1020 1030 1040 1050 1060 KIAA15 CALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFK ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: gi|702 CALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCCPLDTNSCKQGERTSDRDVTVVQFK 880 890 900 910 920 930 1070 1080 1090 1100 1110 1120 KIAA15 SLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|702 SLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNH 940 950 960 970 980 990 1130 1140 1150 1160 1170 1180 KIAA15 KRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSS :.: gi|702 KKK >>gi|194211820|ref|XP_001503163.2| PREDICTED: similar to (1756 aa) initn: 2211 init1: 1565 opt: 4761 Z-score: 4668.5 bits: 876.5 E(): 0 Smith-Waterman score: 4761; 62.907% identity (80.461% similar) in 1259 aa overlap (1-1234:166-1406) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::.: ::.:::: :: .::.::: gi|194 SQQTSFGTNAPNVHPLQNQFVTSDTYSMQLQMIPSSSGSGPVTYQGNPRLNPPLSERQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :.:: :.:::::::: :: : :: .:.: : : :::. .: .:::::::. :::.::: gi|194 WAQQYPSNGLTYPDYRTLPKQYSYSSRSYLQDPT-QKQHSLPAASLQVKNSHPPNSALTL 200 210 220 230 240 250 100 110 120 130 140 KIAA15 PSRQTSAVPSQQYAT-QTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSE :.:.... : :::. :::.::::: :.:::.:::::::::: :: :.:::::::: : gi|194 QSKQAATIQSYQYAVAQTDRRPPPP-YDCRYASQPLQSTQHIIKHSSVEVPQSQEMHLPE 260 270 280 290 300 310 150 160 170 180 190 200 KIAA15 IRT----SFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEK .: .::::::: ::::: :: :::::.. .::.. :::::.:::::: ..: :: gi|194 MRKEFYRGFQQQWQNLNENVSRTGNSCNLKVNSSVSQPYSEPIRSSLDGVQTLPENNPEK 320 330 340 350 360 370 210 220 230 240 250 260 KIAA15 IMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTN .:.:: ::::::::::::::::::::::::::.:::::::::::::.:::::::.: :: gi|194 RVDACNLTSNQVLDTSVAKEKLVRDIKTLVEIKKKFSELARKIKINKNLLMAAGCVKTTN 380 390 400 410 420 430 270 280 290 300 310 320 KIAA15 TSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAE-TNKTQCMLNSDIQ ::::: ::::.:: .:::.::: : .::: : :. . : ..::.: ::.:. :::.:: gi|194 TSYSESAQNSELS-HQTAQIQSRPLVTPVTLEAAKDKPPPAMESVEETNRTHHTLNSNIQ 440 450 460 470 480 490 330 340 350 360 370 380 KIAA15 EVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTS-KTSAVEMTQAVLN-TQLSSENV ..::: ::::.:.: ::: ::: :.:. :..:..:: ::::::.:::.:: ::.:: : gi|194 DTNCRNFNQVNSILQNPVCSEKLPVPNQLHELKIMTSLKTSAVEITQATLNNTQFSSGNF 500 510 520 530 540 550 390 400 410 420 430 440 KIAA15 TKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQD ..:::: :. :: : :.: : ::: :. :.: :.:.::.:. :::. . ::::.:::: gi|194 VSVEQNVPTNSETTSFPQSTSFEEYVSRYPNKNKLILSLLTQGDKTQRKLSKDANKTIQD 560 570 580 590 600 610 450 460 470 480 490 500 KIAA15 SKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSC ::: : : :::::.: :: :::..::::: :..... :.::: .::..:: .:::: : gi|194 SKPHSFERNPNTQITDNQPNLKTVETPSTCNINAKISDDSFCLEGKSSANGMSSKSDSHC 620 630 640 650 660 670 510 520 530 540 550 560 KIAA15 SMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNK ::.::::::::::::: :..::.:. ::::::::::::..: ::: :.::: :::: gi|194 PMELLATCLSLWKKQPSGTTEEKQCNGSRTNTTAVGISKPVEICDKSPFSLVGN--SQNK 680 690 700 710 720 730 570 580 590 600 610 620 KIAA15 ISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETV : ::..:::::..: :::: ..:::::::::.::::.::.::::::: ::: . ::.. gi|194 KVNSSQESALSMVVQNSESSGATVTKGTELQIAIVSPLILSDVKTLSVKEITPEASPEAM 740 750 760 770 780 790 630 640 650 660 670 680 KIAA15 YPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNS ::::::::::::::::::: .::::::. :::::..::::::: :::::::::.:. gi|194 YPVIKEGSVCSLQNQLAENPGVTAALKVNE--PVASTTASTKIFPLFQKEKQNESTKGHL 800 810 820 830 840 690 700 710 720 730 740 KIAA15 EVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQ : :::.:::::.: : : :..: : : ::.: .:. :.:::::::::.::.:::::: gi|194 EGTPNTNQGKHTKSEPDILYPVGDWQASCTSRDSDIVNVDALQIDNICSLAEGNTSYNSQ 850 860 870 880 890 900 750 760 770 780 790 800 KIAA15 IAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHK :::::.: ::: :: :::::::.: :.: :.::::.:::.: :::::. ::::.: : gi|194 IAKIFNSPPLKKVEAQKPSLPNHQVISS---EQQLDNVTENRDSGFQKDNFGQCTDISDK 910 920 930 940 950 960 810 820 830 840 850 860 KIAA15 ICDQSKSEPPLESS-FNNLETNRVILEKSSLEHATE-KSTANDTCSSAAIQEDIYPQEID : ::::: ::: ..:.:.. :.:.:.::: :. .: ::: :: .: :.: . .::: gi|194 IPDQSKSLQLAESSSLKNVEADSGIVEESNLEHITKTESMANDLCSVVASQQDSFLEEID 970 980 990 1000 1010 1020 870 880 890 900 910 920 KIAA15 ASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSE : .:: :::::::. .::. .:::.:::::::::::::::::: :.:::... : : :. gi|194 MSCDYTAQDPARNEVLDDKTSILYLRDQLSELLKEFPYGIEAVNRRNGSVASKLTDQISK 1030 1040 1050 1060 1070 1080 930 940 950 960 970 KIAA15 DQTADKTSSDSKDPAD---QIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEV ::: :. . : :: .: ::::::::::.:::.::::::: .:::.:::::.:.:. gi|194 DQTCDEIGCDPKDSTDSTDQIQITILSSEEMKELFPEQDDQACEADKLTEPQKEKPVTKE 1090 1100 1110 1120 1130 1140 980 990 1000 1010 1020 1030 KIAA15 VSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQ :::: :: . :.: ::: .::::::..:::::::::::::::::::::.:: .::::: gi|194 GSQCDPQAHTDGESSDSVTVDSEKDDVRCCALGWLSMVYEGVPQCQCNSVKNLTSEEEKG 1150 1160 1170 1180 1190 1200 1040 1050 1060 1070 1080 1090 KIAA15 KEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNN----PKTPPDGKSHFPELQDDSRK-- :.:: ::.:::::::: .:::: . :.: .:: : .::::. ::: :.:.... gi|194 KDQCPPLETNSCKQGEGASDRD-DPIGFNSPLNNDPKVPLSPPDGREHFP-LMDQGKNIT 1210 1220 1230 1240 1250 1260 1100 1110 1120 1130 1140 KIAA15 DTPKTKHKSLPRTEQELVAGQFSSKCDK-LNPLQNHKRK-KLRFHEVTFHSSNKMTASYE : . : .: : .::: ..:: :: :: :. ::..::: ::.:::.::::..::: gi|194 DISQLKGNSSPSSEQE-SSSQFLSKGDKKLDSLQSYKRKGKLQFHEITFHSGHKMT---- 1270 1280 1290 1300 1310 1150 1160 1170 1180 1190 1200 KIAA15 QASQETRQKKHVTQNSRPLKTKTAFLPNK--DVYKKHSSLGQSLSPEKIKLKLKSVSFK- . :::. ::. .. :. ::::: .:: :: :.. :..:: :.:::: ::: . . : gi|194 KFSQESLQKRLMAPNACPLKTKMGFLTNKNKDLHMKKGSL-LSVSPEKRKLKAGGCTQKI 1320 1330 1340 1350 1360 1370 1210 1220 1230 1240 KIAA15 -QKRKLDQGNVLDMEVKKKKHDTQDAEKNDLASKGHSPHPQRLK .:::::.:: : :.:::: : .. ..: gi|194 LEKRKLDEGNQLVSEIKKKKCDKREQNRNVGGGTFKLCNFLATSNERANVKEKTVSNVKS 1380 1390 1400 1410 1420 1430 >>gi|11611577|dbj|BAB19003.1| hypothetical protein [Maca (762 aa) initn: 3499 init1: 2909 opt: 4579 Z-score: 4494.9 bits: 843.1 E(): 0 Smith-Waterman score: 4579; 92.318% identity (97.266% similar) in 768 aa overlap (349-1113:1-762) 320 330 340 350 360 370 KIAA15 LNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLS ::::::::::::::::.::::::::::.:: gi|116 MPDPSHDVKVLTSKTSTVEMTQAVLNTRLS 10 20 30 380 390 400 410 420 430 KIAA15 SENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQ :::::::::::::::::::::::.:::::::::::::::::::::::.:::::::::::: gi|116 SENVTKVEQNSPAVCETISVPKSISTEEYKSKIQNENMLLLALLSQAHKTQKTVLKDANQ 40 50 60 70 80 90 440 450 460 470 480 490 KIAA15 TIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKS :::::: :::::::::::::::::::.:::::::::::.::::::::::::::::::::: gi|116 TIQDSKLDSCEMNPNTQMTGNQLNLKTMETPSTSNVSGKVLDNSFCSGQESSTKGMPAKS 100 110 120 130 140 150 500 510 520 530 540 550 KIAA15 DSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSN :: ::::::::::::::::::.:.:::.:::::::::.::::::::::.::::::::::: gi|116 DS-CSMEVLATCLSLWKKQPSETTKEKQCDKLRTNTTVVGISKPANIHIKSPCSVVGNSN 160 170 180 190 200 560 570 580 590 600 610 KIAA15 SQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVL :::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.: gi|116 SQNKISNPSQQTALSMVVHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAAL 210 220 230 240 250 260 620 630 640 650 660 670 KIAA15 PETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNEST ::::::.:::::::::::::::::::.::::::::::::::::::::::::::::::::: gi|116 PETVYPIIKEGSVCSLQNQLAENAKAAAALKVDVSGPVASTATSTKIFPLTQKEKQNEST 270 280 290 300 310 320 680 690 700 710 720 730 KIAA15 NGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTS .::::::::::::::::::::.::: :::: ::::::::::::: ::::::::::::::: gi|116 HGNSEVTPNVNQGKHNKLESAMHSPTNDQQTSQESRNSTVVSSDILQIDNICSLVEGDTS 330 340 350 360 370 380 740 750 760 770 780 790 KIAA15 YNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTD :::::::::::::::::::::::.::::: ::::::::::::.::::::::::::::::: gi|116 YNSQIAKIFSSLPLKMVEPQKPSVPNQQGNGSREPEKQLDNTAENKDFGFQKDKPVQCTD 390 400 410 420 430 440 800 810 820 830 840 850 KIAA15 VSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQE :::::::::: ::::::: :.::::: ::::::.:::::::::::::: ::::::::::: gi|116 VSHKICDQSKLEPPLESSCNDLETNRGILEKSSVEHATEKSTANDTCSLAAIQEDIYPQE 450 460 470 480 490 500 860 870 880 890 900 910 KIAA15 IDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQT ::::::::::::::::::.::::::::::::::::::::::::::::::.::::::.::: gi|116 IDASSNYTPQDPARNEIHNDKAPVLYLHDQLSELLKEFPYGIEAVNTRESSVGQQTAYQT 510 520 530 540 550 560 920 930 940 950 960 970 KIAA15 SEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVV :::::::::::::::::::::::.::::::::::::::::::::: :.::::.::::::: gi|116 SEDQTADKTSSDSKDPADQIQITVLSSEQMKEIFPEQDDQPYVVDDLTEPQKDEPITEVV 570 580 590 600 610 620 980 990 1000 1010 1020 1030 KIAA15 SQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQK . :::.:.:::::.::::::::::::::::::::::::::::::::::.::::::: gi|116 TP----APAGGESRDSVVLDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSTSEEEKQK 630 640 650 660 670 680 1040 1050 1060 1070 1080 1090 KIAA15 EQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPP---DGKSHFPELQDDSRKDTPK :::: :.::::::::::::::::::::::::::::::: :::::::::::..::.: : gi|116 EQCS-LETNSCKQGERTSDRDVTVVQFKSLVNNPKTPPTSPDGKSHFPELQDNNRKETSK 690 700 710 720 730 740 1100 1110 1120 1130 1140 1150 KIAA15 TKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQET :::::::::::::.::.: gi|116 TKHKSLPRTEQELTAGEF 750 760 >>gi|15208227|dbj|BAB63138.1| hypothetical protein [Maca (709 aa) initn: 3084 init1: 3084 opt: 3120 Z-score: 3063.3 bits: 578.2 E(): 6.3e-162 Smith-Waterman score: 3120; 91.683% identity (97.679% similar) in 517 aa overlap (1-517:167-681) 10 20 30 KIAA15 QMIPSNSTRLPVAYQGNQGLNQSFSEQQVD :::::: ::::..::::::::::::::::: gi|152 SHQTDFGTNAPNMPALQSHLVTSDTYSMQMQMIPSNPTRLPAVYQGNQGLNQSFSEQQVD 140 150 160 170 180 190 40 50 60 70 80 90 KIAA15 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL :::::::::::::::::::::::::::::: :::::::::.:.::::::::::::::::: gi|152 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLQDSTIQKQNFMPRTSLQVKNSQLPNSVLTL 200 210 220 230 240 250 100 110 120 130 140 150 KIAA15 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSQEMLSSEI ::.::.:::::::::::::::::::::::: :::::::::.:::::::::::.::::::: gi|152 PSKQTAAVPSQQYATQTDKRPPPPPYNCRYISQPLQSTQHVTKHLSMEVPQSREMLSSEI 260 270 280 290 300 310 160 170 180 190 200 210 KIAA15 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNGPIRSSVDGVQTLAQTNEEKIMDSC ::::::::::::::::::::::::::::.:::: : ::::::::.::::::::::::::: gi|152 RTSFQQQWQNPNENVSTIGNFTNLKVNTSSKQPVNDPIRSSVDGIQTLAQTNEEKIMDSC 320 330 340 350 360 370 220 230 240 250 260 270 KIAA15 NPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSE ::::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::. gi|152 NPTSNQVLDTNVTKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSK 380 390 400 410 420 430 280 290 300 310 320 330 KIAA15 PAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRR :::::.::::::.:::::::.::::::::::: ::::::.::::::::.::::::::::: gi|152 PAQNSQLSLKQTTKIQSGPQVTPVMPENAERQPPTVVESTETNKTQCMMNSDIQEVNCRR 440 450 460 470 480 490 340 350 360 370 380 390 KIAA15 FNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSP :::::::::::::.::::::::::::::.:::::.::::::::::.:::::::::::::: gi|152 FNQVDSVLPNPVYTEKRPMPDPSHDVKVITSKTSTVEMTQAVLNTRLSSENVTKVEQNSP 500 510 520 530 540 550 400 410 420 430 440 450 KIAA15 AVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM :::::::::::.:::::::::::::::::::::::.:::::::::::::::::: ::::: gi|152 AVCETISVPKSISTEEYKSKIQNENMLLLALLSQAHKTQKTVLKDANQTIQDSKLDSCEM 560 570 580 590 600 610 460 470 480 490 500 510 KIAA15 NPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATC ::::::::::::::.:::::::::::.::::::::::::::::::::::: :::: : gi|152 NPNTQMTGNQLNLKTMETPSTSNVSGKVLDNSFCSGQESSTKGMPAKSDS-CSME-LEET 620 630 640 650 660 670 520 530 540 550 560 570 KIAA15 LSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQT ...::.. gi|152 IKVWKQRTHVMRFFHETEAPRPKDFLSKFYVGHDP 680 690 700 1249 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Thu Mar 5 02:04:50 2009 done: Thu Mar 5 02:08:15 2009 Total Scan time: 1749.160 Total Display time: 1.130 Function used was FASTA [version 34.26.5 April 26, 2007]