hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-06021157/chunk_1/iprscan-20080502-06021157.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1550 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF08337.2.ls Plexin cytoplasmic region 1380.5 0 1 PF08337.2.fs Plexin cytoplasmic region 1378.7 0 1 PF01833.14.ls IPT/TIG domain 193.8 3.8e-55 4 PF01833.14.fs IPT/TIG domain 193.2 4.3e-55 5 PF01437.15.fs Plexin repeat 160.4 7e-52 3 PF01437.15.ls Plexin repeat 165.7 1.1e-46 3 PF01403.10.fs Sema domain 33.2 3.6e-09 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF01403.10.fs 1/1 1 58 [. 420 490 .] 33.2 3.6e-09 PF01437.15.fs 1/3 77 127 .. 1 63 [] 68.4 8.8e-22 PF01437.15.ls 1/3 77 127 .. 1 63 [] 70.1 6.4e-18 PF01437.15.fs 2/3 223 270 .. 1 63 [] 41.5 5.3e-13 PF01437.15.ls 2/3 223 270 .. 1 63 [] 43.3 7.9e-10 PF01437.15.fs 3/3 371 424 .. 1 63 [] 50.5 6.3e-16 PF01437.15.ls 3/3 371 424 .. 1 63 [] 52.3 1.5e-12 PF01833.14.ls 1/4 426 519 .. 1 104 [] 62.2 1.6e-15 PF01833.14.fs 2/5 426 519 .. 1 104 [] 60.4 8.6e-17 PF01833.14.ls 2/4 522 604 .. 1 104 [] 61.8 2.1e-15 PF01833.14.fs 3/5 522 604 .. 1 104 [] 60.0 1.1e-16 PF01833.14.fs 4/5 608 706 .. 1 104 [] 45.1 2.1e-12 PF01833.14.ls 3/4 608 706 .. 1 104 [] 47.0 6e-11 PF01833.14.fs 5/5 710 774 .. 1 73 [. 23.9 2.9e-06 PF01833.14.ls 4/4 710 797 .. 1 104 [] 22.8 0.0011 PF08337.2.fs 1/1 878 1432 .. 1 586 [] 1378.7 0 PF08337.2.ls 1/1 878 1432 .. 1 586 [] 1380.5 0 Alignments of top-scoring domains: PF01403.10.fs: domain 1 of 1, from 1 to 58: score 33.2, E = 3.6e-09 *->TqIaVdkrVragdGqlYtVlFlGTddGtvlKkvvvlsrssssyeevv T+++++ + + + +F+GT++G+++K++v+ +r+ + ++ KIAA1550 1 TSVIAY---VYKN---HSLAFVGTKSGKLKKIRVDGPRGNA----LQ 37 leelqvfkdpriePvqnleisskq<-* +e +qv+ ++ Pv++++++sk+ KIAA1550 38 YETVQVVDPG---PVLRDMAFSKD 58 PF01437.15.fs: domain 1 of 3, from 77 to 127: score 68.4, E = 8.8e-22 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse. +C+qy+sC++CL++ dp +CgWC+++++Ctr++ C+rs++ KIAA1550 77 SCGQYQSCGECLGSGDP-HCGWCVLHNTCTRKE-------RCERSKe 115 pendqwldwswssskCp<-* p+ ++++ ++C+ KIAA1550 116 PR-----RFASEMKQCV 127 PF01437.15.ls: domain 1 of 3, from 77 to 127: score 70.1, E = 6.4e-18 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse. +C+qy+sC++CL++ dp +CgWC+++++Ctr++ C+rs++ KIAA1550 77 SCGQYQSCGECLGSGDP-HCGWCVLHNTCTRKE-------RCERSKe 115 pendqwldwswssskCp<-* p+ ++++ ++C+ KIAA1550 116 PR-----RFASEMKQCV 127 PF01437.15.fs: domain 2 of 3, from 223 to 270: score 41.5, E = 5.3e-13 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep nCs++ sC sC++++ +C+WC++++ Ct+ + C+ +e KIAA1550 223 NCSVHNSCLSCVESPY--RCHWCKYRHVCTHDPK------TCSFQE- 260 endqwldwswssskCp<-* +++ ++Cp KIAA1550 261 ------GRVKLPEDCP 270 PF01437.15.ls: domain 2 of 3, from 223 to 270: score 43.3, E = 7.9e-10 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep nCs++ sC sC++++ +C+WC++++ Ct+ + C+ +e KIAA1550 223 NCSVHNSCLSCVESPY--RCHWCKYRHVCTHDPK------TCSFQE- 260 endqwldwswssskCp<-* +++ ++Cp KIAA1550 261 ------GRVKLPEDCP 270 PF01437.15.fs: domain 3 of 3, from 371 to 424: score 50.5, E = 6.3e-16 *->nCsqy.tsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse +C++++ sC+ CL a++ f CgWC++ g+Ct+++ +Cp +e KIAA1550 371 KCGAMrESCGLCLKADPDFACGWCQGPGQCTLRQ-------HCPAQE 410 pendqwldwswssskCp<-* +qwl+ s + skC+ KIAA1550 411 ---SQWLELSGAKSKCT 424 PF01437.15.ls: domain 3 of 3, from 371 to 424: score 52.3, E = 1.5e-12 *->nCsqy.tsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse +C++++ sC+ CL a++ f CgWC++ g+Ct+++ +Cp +e KIAA1550 371 KCGAMrESCGLCLKADPDFACGWCQGPGQCTLRQ-------HCPAQE 410 pendqwldwswssskCp<-* +qwl+ s + skC+ KIAA1550 411 ---SQWLELSGAKSKCT 424 PF01833.14.ls: domain 1 of 4, from 426 to 519: score 62.2, E = 1.6e-15 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P+It+i P +gp +GGt +Ti+G+nlg f d +V+ KIAA1550 426 PRITEIIPVTGPREGGTKVTIRGENLG---------LEFRDIASHVK 463 fggtpvpCdvisssss..tqivCktPpva.ggpsppv..vtvsvdgggsg ++g++ C + ++ +++ +qivC+ +++ + +++ v + v +++ + KIAA1550 464 VAGVE--CSPLVDGYIpaEQIVCEMGEAKpSQ---HAgfVEICVAVCR-P 507 dgrssspvtFtY<-* ++ s++ +++ KIAA1550 508 EFMARSSQLYYF 519 PF01833.14.fs: domain 2 of 5, from 426 to 519: score 60.4, E = 8.6e-17 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P+It+i P +gp +GGt +Ti+G+nlg f d +V+ KIAA1550 426 PRITEIIPVTGPREGGTKVTIRGENLG---------LEFRDIASHVK 463 fggtpvpCdvisssss..tqivCktPpva.ggpsppv..vtvsvdgggsg ++g++ C + ++ +++ +qivC+ +++ + +++ v + v +++ + KIAA1550 464 VAGVE--CSPLVDGYIpaEQIVCEMGEAKpSQ---HAgfVEICVAVCR-P 507 dgrssspvtFtY<-* ++ s++ +++ KIAA1550 508 EFMARSSQLYYF 519 PF01833.14.ls: domain 2 of 4, from 522 to 604: score 61.8, E = 2.1e-15 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt ++ +++ Ps+gp sGGt++TitG+nl++gs ++ V KIAA1550 522 LTLSDLKPSRGPMSGGTQVTITGTNLNAGS------------NVVVM 556 fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs fg +p C ++++s + ivC t ++ + + v v+vd++ + KIAA1550 557 FGKQP--CLFHRRSP-SYIVCNTTSSDeVLEMK--VSVQVDRAK-----I 596 sspvtFtY<-* + F+Y KIAA1550 597 HQDLVFQY 604 PF01833.14.fs: domain 3 of 5, from 522 to 604: score 60.0, E = 1.1e-16 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt ++ +++ Ps+gp sGGt++TitG+nl++gs ++ V KIAA1550 522 LTLSDLKPSRGPMSGGTQVTITGTNLNAGS------------NVVVM 556 fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs fg +p C ++++s + ivC t ++ + + v v+vd++ + KIAA1550 557 FGKQP--CLFHRRSP-SYIVCNTTSSDeVLEMK--VSVQVDRAK-----I 596 sspvtFtY<-* + F+Y KIAA1550 597 HQDLVFQY 604 PF01833.14.fs: domain 4 of 5, from 608 to 706: score 45.1, E = 2.1e-12 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P+I +i+P+++ +sG+t i + G++l+ +++P+ir + KIAA1550 608 PTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIR----------AK 644 fggtpv..pCdvissssstqivCktPpva.ggpsppv.......vtvsvd gg++ + C+v + ++ ++C P++a g + +++++++ + +d KIAA1550 645 HGGKEHinICEVLNATE---MTCQAPALAlGPDHQSDlterpeeFGFILD 691 gggsgdgrssspvtFtY<-* +++ +++ + + FtY KIAA1550 692 NVQ--SLLILNKTNFTY 706 PF01833.14.ls: domain 3 of 4, from 608 to 706: score 47.0, E = 6e-11 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P+I +i+P+++ +sG+t i + G++l+ +++P+ir + KIAA1550 608 PTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIR----------AK 644 fggtpv..pCdvissssstqivCktPpva.ggpsppv.......vtvsvd gg++ + C+v + ++ ++C P++a g + +++++++ + +d KIAA1550 645 HGGKEHinICEVLNATE---MTCQAPALAlGPDHQSDlterpeeFGFILD 691 gggsgdgrssspvtFtY<-* +++ +++ + + FtY KIAA1550 692 NVQ--SLLILNKTNFTY 706 PF01833.14.fs: domain 5 of 5, from 710 to 774: score 23.9, E = 2.9e-06 *->PvItsisP.ssgplsGGteiTitGsnlgsgse.Prirk.ntfededi Pv+++++P+ l++Gt i+++G+nl + +++++ +++t KIAA1550 710 PVFEAFGPsGILELKPGTPIILKGKNLIPPVAgGNVKLnYT------ 750 kVtfggtpvpCdvissssstqivCktPpv<-* V++g++p C+v++s+ q+ C++P++ KIAA1550 751 -VLVGEKP--CTVTVSD--VQLLCESPNL 774 PF01833.14.ls: domain 4 of 4, from 710 to 797: score 22.8, E = 0.0011 *->PvItsisP.ssgplsGGteiTitGsnlgsgseP.rirk.ntfededi Pv+++++P+ l++Gt i+++G+nl + +++++ +++t KIAA1550 710 PVFEAFGPsGILELKPGTPIILKGKNLIPPVAGgNVKLnYT------ 750 kVtfggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgd V++g++p C+v++s+ q+ C++P++ + ++ v+ v+g + KIAA1550 751 -VLVGEKP--CTVTVSD--VQLLCESPNLIgRHK----VMARVGGME--- 788 grssspvtFtY<-* +s + + KIAA1550 789 --YSPGMVYIA 797 PF08337.2.fs: domain 1 of 1, from 878 to 1432: score 1378.7, E = 0 *->sGiPfLDYktYaeRvFFpkpGhedHPvLkdlevpesraptveegLtq +GiPfLDY+tY++Rv+F pG+edHPvL+dlevp+ r+++ve+gL++ KIAA1550 878 AGIPFLDYRTYTMRVLF--PGIEDHPVLRDLEVPGYRQERVEKGLKL 922 FsqLLnNKsFLltfIhTLEsQrsFSvRDRvnvASLLmvaLqgKLeYcTdI F qL+nNK+FLl fI+TLEsQrsFS+RDR+nvASL+m++Lq+KLeY+Td+ KIAA1550 923 FAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDV 972 LktLLrdLIeksvesKnnPKLmLRRTESVVEKMLTNWmSiCLYdfLKeta Lk+LL dLI+k++esKn+PKL+LRRTESV+EKMLTNW++++LY+fLKe+a KIAA1550 973 LKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECA 1022 GepLflLfkAIKqQieKGPVDAvTgkARYTLnEekLLReqveykpltlnC GepLf Lf+AIKqQ+eKGP+DA+Tg+ARY+L+E+kL+R+q++yk+l l+C KIAA1550 1023 GEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSC 1072 VilevqpegdeadgvrnvpVkVLDCDTItQVKeKiLdavYkgtPySqRPr V+ +++ ++ + vpVk L+CDTItQVKeKiLda++k++P+S RP+ KIAA1550 1073 VS--PDNANSPE-----VPVKILNCDTITQVKEKILDAIFKNVPCSHRPK 1115 vedldLEWrtGrrghliLqDveDvTskiegglwKRLNTLaHYgVpDGAtl + d+dLEWr+G+++++iLqD eD+T+kie++ wKRLNTLaHY+VpDG+++ KIAA1550 1116 AADMDLEWRQGSGARMILQD-EDITTKIEND-WKRLNTLAHYQVPDGSVV 1163 aLvpkqntassynisilStksekstsiltdnssryestlrldssddslgs aLv+kq+ +yn + ++ +++++ s+ye++ r++ s+dsl+s KIAA1550 1164 ALVSKQV--TAYNAV-------NNSTVSRTSASKYENMIRYTGSPDSLRS 1204 rsdlledgqesGvklwHLVkPtdelveqkkgkRqslklkeredrkKaipE r+++++++ esGvk wHLVk++++ +qk+g+R ++K+++E KIAA1550 1205 RTPMITPDLESGVKMWHLVKNHEH-GDQKEGDR----------GSKMVSE 1243 IYLTRLLstKGTLQKFVDDLFesILStaHrnsalPlAvKYfFDFLDeqAe IYLTRLL+tKGTLQKFVDDLFe+I+StaHr+salPlA+KY+FDFLDeqA+ KIAA1550 1244 IYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQAD 1293 khgIsDpDvvHiWKsNsLPLRFWVNiiKNPqFVFDIhKtdsvDAcLSViA khgI+Dp v+H+WKsN+LPLRFWVN iKNPqFVFDIhK++++DAcLSV+A KIAA1550 1294 KHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVA 1343 QTFMDACStsEhrLGKDSPSNKLLYAKDIPrYkkmVerYYkdIrdmppiS QTFMD+CStsEhrLGKDSPSNKLLYAKDIP Yk +VerYY dI +mp+iS KIAA1550 1344 QTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAIS 1393 dQEMnaaLaeeSrkhsnefntlvALnELYkYvkKYrdqI<-* dQ+Mna+Lae+Sr h nefnt +AL+E+ +Yv KY ++I KIAA1550 1394 DQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEI 1432 PF08337.2.ls: domain 1 of 1, from 878 to 1432: score 1380.5, E = 0 *->sGiPfLDYktYaeRvFFpkpGhedHPvLkdlevpesraptveegLtq +GiPfLDY+tY++Rv+F pG+edHPvL+dlevp+ r+++ve+gL++ KIAA1550 878 AGIPFLDYRTYTMRVLF--PGIEDHPVLRDLEVPGYRQERVEKGLKL 922 FsqLLnNKsFLltfIhTLEsQrsFSvRDRvnvASLLmvaLqgKLeYcTdI F qL+nNK+FLl fI+TLEsQrsFS+RDR+nvASL+m++Lq+KLeY+Td+ KIAA1550 923 FAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDV 972 LktLLrdLIeksvesKnnPKLmLRRTESVVEKMLTNWmSiCLYdfLKeta Lk+LL dLI+k++esKn+PKL+LRRTESV+EKMLTNW++++LY+fLKe+a KIAA1550 973 LKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECA 1022 GepLflLfkAIKqQieKGPVDAvTgkARYTLnEekLLReqveykpltlnC GepLf Lf+AIKqQ+eKGP+DA+Tg+ARY+L+E+kL+R+q++yk+l l+C KIAA1550 1023 GEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSC 1072 VilevqpegdeadgvrnvpVkVLDCDTItQVKeKiLdavYkgtPySqRPr V+ +++ ++ + vpVk L+CDTItQVKeKiLda++k++P+S RP+ KIAA1550 1073 VS--PDNANSPE-----VPVKILNCDTITQVKEKILDAIFKNVPCSHRPK 1115 vedldLEWrtGrrghliLqDveDvTskiegglwKRLNTLaHYgVpDGAtl + d+dLEWr+G+++++iLqD eD+T+kie++ wKRLNTLaHY+VpDG+++ KIAA1550 1116 AADMDLEWRQGSGARMILQD-EDITTKIEND-WKRLNTLAHYQVPDGSVV 1163 aLvpkqntassynisilStksekstsiltdnssryestlrldssddslgs aLv+kq+ +yn + ++ +++++ s+ye++ r++ s+dsl+s KIAA1550 1164 ALVSKQV--TAYNAV-------NNSTVSRTSASKYENMIRYTGSPDSLRS 1204 rsdlledgqesGvklwHLVkPtdelveqkkgkRqslklkeredrkKaipE r+++++++ esGvk wHLVk++++ +qk+g+R ++K+++E KIAA1550 1205 RTPMITPDLESGVKMWHLVKNHEH-GDQKEGDR----------GSKMVSE 1243 IYLTRLLstKGTLQKFVDDLFesILStaHrnsalPlAvKYfFDFLDeqAe IYLTRLL+tKGTLQKFVDDLFe+I+StaHr+salPlA+KY+FDFLDeqA+ KIAA1550 1244 IYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQAD 1293 khgIsDpDvvHiWKsNsLPLRFWVNiiKNPqFVFDIhKtdsvDAcLSViA khgI+Dp v+H+WKsN+LPLRFWVN iKNPqFVFDIhK++++DAcLSV+A KIAA1550 1294 KHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVA 1343 QTFMDACStsEhrLGKDSPSNKLLYAKDIPrYkkmVerYYkdIrdmppiS QTFMD+CStsEhrLGKDSPSNKLLYAKDIP Yk +VerYY dI +mp+iS KIAA1550 1344 QTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAIS 1393 dQEMnaaLaeeSrkhsnefntlvALnELYkYvkKYrdqI<-* dQ+Mna+Lae+Sr h nefnt +AL+E+ +Yv KY ++I KIAA1550 1394 DQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEI 1432 //