hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-19163148/chunk_1/iprscan-20080501-19163148.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1168 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF05994.2.ls Cytoplasmic Fragile-X interacting family 3663.4 0 1 PF05994.2.fs Cytoplasmic Fragile-X interacting family 3659.9 0 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF05994.2.fs 1/2 27 583 .. 1 565 [. 1623.9 0 PF05994.2.ls 1/1 27 1304 .] 1 1293 [] 3663.4 0 PF05994.2.fs 2/2 609 1304 .] 566 1293 .] 2036.0 0 Alignments of top-scoring domains: PF05994.2.fs: domain 1 of 2, from 27 to 583: score 1623.9, E = 0 *->MtakvTldDAlSNVelLdeLalPDdqPcIEarplsilYraNFDTNFE Mt++vTl+DAlSNV+lL+eL+lPD+qPcIE++p+si+Y+aNFDTNFE KIAA1168 27 MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFE 73 DRnaFVTGIAkYiEeATrHaqlNdmLeEglkhAvmlYTWRcCSRAiPqaK DRnaFVTGIA+YiE+AT+H+++N+mLeEg+++AvmlYTWR+CSRAiPq+K KIAA1168 74 DRNAFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVK 123 sNeQPNRvEIyEktVEVLkPEVsKLlkFMyFqrkAIerFceEVkRLCHaE +NeQPNRvEIyEktVEVL+PEV+KL+kFMyFqrkAIerFc+EVkRLCHaE KIAA1168 124 CNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAE 173 kRkDFVSEAYLLTLGkFINMFAVLDELKNMKaSvKNDfStyrRAaQFLka +RkDFVSEAYLLTLGkFINMFAVLDELKNMK+SvKND+S+y+RAaQFL++ KIAA1168 174 RRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRK 223 MsDtqavqesQNLSMFLAtqNkIkddlkdqletIeGYEeLLaDvVNICvh M+D+q++qesQNLSMFLA++N+I+++l++qle+I+GYEeLLaD+VNICv+ KIAA1168 224 MADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVD 273 mYEtklYLtPeEKHMlvKVmgFgLFLMDgdaaNiaKLDqKKrislsriDk +YE+k+YLtP+EKHMl+KVmgFgL+LMDg+++Ni+KLD+KKri+ls+iDk KIAA1168 274 YYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDK 323 iFKtLeVVPLfGDMQIepfayikrSsHYeenkSKWpLsdkesispqvniv +FK+L+VVPLfGDMQIe+++yi +S+HYeenkSKW+ ++++sispq+ni+ KIAA1168 324 FFKQLQVVPLFGDMQIELARYIETSAHYEENKSKWT-CTQSSISPQYNIC 372 eklqqIReDHvkYiselArysNevavtGsGldeqksDsEnReitdLALrG e+++qIR+DH+++iselArysN+++vtGsGld+qksD+E+Re++dLALrG KIAA1168 373 EQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRG 422 lQLLskWsaaVvEvySWKLlhPTdkkdNkeCPeeAEEYERATRYNYtseE lQLLskWsa+V+EvySWKL+hPTdk++Nk+CP++AEEYERATRYNYtseE KIAA1168 423 LQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEE 472 KfALievIAMIKGLQvllgriEsvlseaiRktiYveLQdFvqltlrEPLr KfA++evIAMIKGLQvl+gr+Esv+++aiR+tiY++LQdF+q+tlrEPLr KIAA1168 473 KFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLR 522 kAVkkKKdllaSilqsvrdtisDwekgleptdDvkGkkkspaakGdkdps +AV+kKK++l+S+lq++r+ti+Dwe+g+ep++D p+++G+kdp+ KIAA1168 523 QAVRKKKNVLISVLQAIRKTICDWEGGREPPND-------PCLRGEKDPK 565 ggfdIrvPRrtvgPsSTQ<-* ggfdI+vPRr+vgPsSTQ KIAA1168 566 GGFDIKVPRRAVGPSSTQ 583 PF05994.2.ls: domain 1 of 1, from 27 to 1304: score 3663.4, E = 0 *->MtakvTldDAlSNVelLdeLalPDdqPcIEarplsilYraNFDTNFE Mt++vTl+DAlSNV+lL+eL+lPD+qPcIE++p+si+Y+aNFDTNFE KIAA1168 27 MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFE 73 DRnaFVTGIAkYiEeATrHaqlNdmLeEglkhAvmlYTWRcCSRAiPqaK DRnaFVTGIA+YiE+AT+H+++N+mLeEg+++AvmlYTWR+CSRAiPq+K KIAA1168 74 DRNAFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVK 123 sNeQPNRvEIyEktVEVLkPEVsKLlkFMyFqrkAIerFceEVkRLCHaE +NeQPNRvEIyEktVEVL+PEV+KL+kFMyFqrkAIerFc+EVkRLCHaE KIAA1168 124 CNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAE 173 kRkDFVSEAYLLTLGkFINMFAVLDELKNMKaSvKNDfStyrRAaQFLka +RkDFVSEAYLLTLGkFINMFAVLDELKNMK+SvKND+S+y+RAaQFL++ KIAA1168 174 RRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRK 223 MsDtqavqesQNLSMFLAtqNkIkddlkdqletIeGYEeLLaDvVNICvh M+D+q++qesQNLSMFLA++N+I+++l++qle+I+GYEeLLaD+VNICv+ KIAA1168 224 MADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVD 273 mYEtklYLtPeEKHMlvKVmgFgLFLMDgdaaNiaKLDqKKrislsriDk +YE+k+YLtP+EKHMl+KVmgFgL+LMDg+++Ni+KLD+KKri+ls+iDk KIAA1168 274 YYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDK 323 iFKtLeVVPLfGDMQIepfayikrSsHYeenkSKWpLsdkesispqvniv +FK+L+VVPLfGDMQIe+++yi +S+HYeenkSKW+ ++++sispq+ni+ KIAA1168 324 FFKQLQVVPLFGDMQIELARYIETSAHYEENKSKWT-CTQSSISPQYNIC 372 eklqqIReDHvkYiselArysNevavtGsGldeqksDsEnReitdLALrG e+++qIR+DH+++iselArysN+++vtGsGld+qksD+E+Re++dLALrG KIAA1168 373 EQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRG 422 lQLLskWsaaVvEvySWKLlhPTdkkdNkeCPeeAEEYERATRYNYtseE lQLLskWsa+V+EvySWKL+hPTdk++Nk+CP++AEEYERATRYNYtseE KIAA1168 423 LQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEE 472 KfALievIAMIKGLQvllgriEsvlseaiRktiYveLQdFvqltlrEPLr KfA++evIAMIKGLQvl+gr+Esv+++aiR+tiY++LQdF+q+tlrEPLr KIAA1168 473 KFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLR 522 kAVkkKKdllaSilqsvrdtisDwekgleptdDvkGkkkspaakGdkdps +AV+kKK++l+S+lq++r+ti+Dwe+g+ep++D p+++G+kdp+ KIAA1168 523 QAVRKKKNVLISVLQAIRKTICDWEGGREPPND-------PCLRGEKDPK 565 ggfdIrvPRrtvgPsSTQ.........................LYMvRTm ggfdI+vPRr+vgPsSTQ + +++ +++++++++++ ++ LYMvRTm KIAA1168 566 GGFDIKVPRRAVGPSSTQacqwspralfhptggtqgrrgcrslLYMVRTM 615 LESLIaDKlsGgKktLRkelDgkiilkIevFhkkSfywsaLlnlSdslqe LESLIaDK sG+KktLR++lDg+i+l+Ie+Fhk+Sf++++Lln+S++lq+ KIAA1168 616 LESLIADK-SGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQ 664 ccdLSQLWFREFYLEmTMGrkvnkclvrhqhneeckdlitmekRIQFPIE ccdLSQLWFREF+LE+TMGr RIQFPIE KIAA1168 665 CCDLSQLWFREFFLELTMGR-----------------------RIQFPIE 691 MSMPWILTDhILetkEPSlmEyvLYpLDLYNDsAyYaltkFkKQFLYDEv MSMPWILTDhILetkEPS+mEyvLYpLDLYNDsAyYaltkFkKQFLYDE+ KIAA1168 692 MSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEI 741 EAEVNLCFDQFVYKLseqiFahYKqLAgsvLLDKRFraEckrlGviirsy EAEVNLCFDQFVYKL++qiFa+YK++AgsvLLDKRFraEck++Gvii+ y KIAA1168 742 EAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIP-Y 790 PsanRyEtLLkQRHVQLLGRSiDLNrlitQRinaallKsldaAIsrFEse P++nRyEtLLkQRHVQLLGRSiDLNrlitQRi+aa++Ksld+AIsrFEse KIAA1168 791 PPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESE 840 dltsIVELemLleiNRlcHkLLskvLhsldsFDdlfkEANHnVnaPyGRI dltsIVELe+LleiNRl+H+LL+k++ +ldsFD++f+EANHnV+aPyGRI KIAA1168 841 DLTSIVELEWLLEINRLTHRLLCKHM-TLDSFDAMFREANHNVSAPYGRI 889 TLHVFwELNYDFlpNycYNgsTnRFvRtkvvfssrqepqReKPpqvsqyY TLHVFwELN+DFlpNycYNgsTnRFvRt+++f +qepqR+KP++v++yY KIAA1168 890 TLHVFWELNFDFLPNYCYNGSTNRFVRTAIPF--TQEPQRDKPANVQPYY 937 lwGSKsLnaAysniynaYsqfvGtpHfkaicRLLgYQGIAVvldelLKdi l+GSK+Ln+Ays+iy++Y++fvG+pHfk+icRLLgYQGIAVv++elLK i KIAA1168 938 LYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLK-I 986 vkrLlqgkilqyvktlievMPKvCkLPRseYGSpgvLeYYvhhLedivkY vk+Llqg+ilqyvktlievMPK+C+LPR+eYGSpg+Le+++h+L+di++Y KIAA1168 987 VKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEY 1036 pelKtelfQsLRElGNaIvFClliEqALsQEEvcDLlhAAafqnilPrpy +elKt++fQsLRE+GNaI+FClliEqALsQEEvcDLlhAA+fqnilPr+y KIAA1168 1037 AELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVY 1086 ikeaekqekklkrLEakYarlhlveiiekigtddGQaaIAregdLlTkER ike+e++e+++krLEakYa+lhlv++ie++gt++ Q+aIAregdLlTkER KIAA1168 1087 IKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQ-QIAIAREGDLLTKER 1135 LCCGLsiFEviLvRiksyLaaDpiWtGppPtNGvihvDECvEfhRlwSAL LCCGLs+FEviL+Ri+syL +DpiW+GppPtNGv+hvDECvEfhRlwSA+ KIAA1168 1136 LCCGLSMFEVILTRIRSYL-QDPIWRGPPPTNGVMHVDECVEFHRLWSAM 1184 QFvyCiPvrddnEvtaEelFGdgLnWaGctlIvLLGQqRRFevLDFCYHl QFvyCiPv+ +nE+taE++FGdgLnWaGc++IvLLGQqRRF+++DFCYHl KIAA1168 1185 QFVYCIPVG-TNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHL 1233 lrVqraDGKDEvikgirLkkMvdRIRrFQvLNnqiFiILnkyLkenedds l+Vqr+DGKDE+ik+++LkkM+dRIR++Q+LNn++F+ILnky+k++e+ds KIAA1168 1234 LKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDS 1283 stVEhVRcFaPPvHpslassa<-* stVEhVRcF+PP+H+sla+++ KIAA1168 1284 STVEHVRCFQPPIHQSLATTC 1304 PF05994.2.fs: domain 2 of 2, from 609 to 1304: score 2036.0, E = 0 *->LYMvRTmLESLIaDKlsGgKktLRkelDgkiilkIevFhkkSfywsa LYMvRTmLESLIaDK sG+KktLR++lDg+i+l+Ie+Fhk+Sf++++ KIAA1168 609 LYMVRTMLESLIADK-SGSKKTLRSSLDGPIVLAIEDFHKQSFFFTH 654 LlnlSdslqeccdLSQLWFREFYLEmTMGrkvnkclvrhqhneeckdlit Lln+S++lq+ccdLSQLWFREF+LE+TMGr KIAA1168 655 LLNISEALQQCCDLSQLWFREFFLELTMGR-------------------- 684 mekRIQFPIEMSMPWILTDhILetkEPSlmEyvLYpLDLYNDsAyYaltk RIQFPIEMSMPWILTDhILetkEPS+mEyvLYpLDLYNDsAyYaltk KIAA1168 685 ---RIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTK 731 FkKQFLYDEvEAEVNLCFDQFVYKLseqiFahYKqLAgsvLLDKRFraEc FkKQFLYDE+EAEVNLCFDQFVYKL++qiFa+YK++AgsvLLDKRFraEc KIAA1168 732 FKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAEC 781 krlGviirsyPsanRyEtLLkQRHVQLLGRSiDLNrlitQRinaallKsl k++Gvii+ yP++nRyEtLLkQRHVQLLGRSiDLNrlitQRi+aa++Ksl KIAA1168 782 KNYGVIIP-YPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSL 830 daAIsrFEsedltsIVELemLleiNRlcHkLLskvLhsldsFDdlfkEAN d+AIsrFEsedltsIVELe+LleiNRl+H+LL+k++ +ldsFD++f+EAN KIAA1168 831 DQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHM-TLDSFDAMFREAN 879 HnVnaPyGRITLHVFwELNYDFlpNycYNgsTnRFvRtkvvfssrqepqR HnV+aPyGRITLHVFwELN+DFlpNycYNgsTnRFvRt+++f +qepqR KIAA1168 880 HNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPF--TQEPQR 927 eKPpqvsqyYlwGSKsLnaAysniynaYsqfvGtpHfkaicRLLgYQGIA +KP++v++yYl+GSK+Ln+Ays+iy++Y++fvG+pHfk+icRLLgYQGIA KIAA1168 928 DKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIA 977 VvldelLKdivkrLlqgkilqyvktlievMPKvCkLPRseYGSpgvLeYY Vv++elLK ivk+Llqg+ilqyvktlievMPK+C+LPR+eYGSpg+Le++ KIAA1168 978 VVMEELLK-IVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFF 1026 vhhLedivkYpelKtelfQsLRElGNaIvFClliEqALsQEEvcDLlhAA +h+L+di++Y+elKt++fQsLRE+GNaI+FClliEqALsQEEvcDLlhAA KIAA1168 1027 HHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAA 1076 afqnilPrpyikeaekqekklkrLEakYarlhlveiiekigtddGQaaIA +fqnilPr+yike+e++e+++krLEakYa+lhlv++ie++gt++ Q+aIA KIAA1168 1077 PFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQ-QIAIA 1125 regdLlTkERLCCGLsiFEviLvRiksyLaaDpiWtGppPtNGvihvDEC regdLlTkERLCCGLs+FEviL+Ri+syL +DpiW+GppPtNGv+hvDEC KIAA1168 1126 REGDLLTKERLCCGLSMFEVILTRIRSYL-QDPIWRGPPPTNGVMHVDEC 1174 vEfhRlwSALQFvyCiPvrddnEvtaEelFGdgLnWaGctlIvLLGQqRR vEfhRlwSA+QFvyCiPv+ +nE+taE++FGdgLnWaGc++IvLLGQqRR KIAA1168 1175 VEFHRLWSAMQFVYCIPVG-TNEFTAEQCFGDGLNWAGCSIIVLLGQQRR 1223 FevLDFCYHllrVqraDGKDEvikgirLkkMvdRIRrFQvLNnqiFiILn F+++DFCYHll+Vqr+DGKDE+ik+++LkkM+dRIR++Q+LNn++F+ILn KIAA1168 1224 FDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILN 1273 kyLkeneddsstVEhVRcFaPPvHpslassa<-* ky+k++e+dsstVEhVRcF+PP+H+sla+++ KIAA1168 1274 KYMKSVETDSSTVEHVRCFQPPIHQSLATTC 1304 //