# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/hg03758b.fasta.huge -Q ../query/KIAA1133.ptfa ./tmplib.24314 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1133, 891 aa
 vs ./tmplib.24314 library

1986614 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 7.5027+/-0.00786; mu= 6.7624+/- 0.534
 mean_var=258.9504+/-63.189, 0's: 0 Z-trim: 6  B-trim: 0 in 0/40
 Lambda= 0.079701

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1214  ( 462 res)   fh01431                     ( 462)  264 43.8 5.6e-05
KIAA1100  ( 444 res)   hk07907                     ( 444)  207 37.2  0.0051


>>KIAA1214  ( 462 res)   fh01431                          (462 aa)
 initn: 296 init1: 247 opt: 264  Z-score: 181.2  bits: 43.8 E(): 5.6e-05
Smith-Waterman score: 298;  26.129% identity (50.323% similar) in 310 aa overlap (13-305:107-360)

                                 10        20                30    
KIAA11                   AAAGPGAARAKETAFVEVVLFESSPS--------GDYTTYTT
                                     ::::...  : .:.        :    .: 
KIAA12 SLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYAEPAPDPGAGAAGGGGAELHTE
         80        90       100       110       120       130      

            40        50           60        70          80        
KIAA11 GLT-GRFSRAGATLSAEGEIVQM---HPLGLCNNNDEEDLYEYG--WVGVVKLEQPELDP
           ::... .   .:.::.:.    :    :. : .      :  :....        :
KIAA12 KTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPTRGKNWIALI--------P
        140       150       160       170       180                

       90       100        110        120       130       140      
KIAA11 KPCLTVLGKAKRAVQRGATAV-IFDVSENP-EAIDQLNQGSEDPLKRPVVYVKGADAIKL
       :   :   : . :  ..:.:: ::.:. :  :.: . . : :: .   .   :: . ..:
KIAA12 KGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIMIPEPKGKEIVSL
      190       200       210       220       230       240        

        150       160       170       180       190       200      
KIAA11 MNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSM
       .                         . .: ........   :        : ::    .
KIAA12 L-------------------------ERNITVTMYITIGTRNL-------QKYRR----L
                               250       260              270      

        210       220       230       240       250       260      
KIAA11 NRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPC
       .  : .:. :.. : ..   :: .:         . :. ..::.:.: :  .. .:..::
KIAA12 GDAAKKAISKLQIRTIK---KGDKE---------TESDFDNCAVCIEGYKPNDVVRILPC
            280          290                300       310       320

        270       280       290        300       310       320     
KIAA11 THRFHRKCVDPWLLQHHTCPHCRHNIIEQKG-NPSAVCVETSNLSRGRQQRVTLPVHYPG
        : ::..:::::::.:.::: :. ::..  :  :.: :..                    
KIAA12 RHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPTNQITG
              330       340       350       360       370       380

         330       340       350       360       370       380     
KIAA11 RVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAA
                                                                   
KIAA12 ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSDISLIM
              390       400       410       420       430       440

>>KIAA1100  ( 444 res)   hk07907                          (444 aa)
 initn: 203 init1: 163 opt: 207  Z-score: 146.0  bits: 37.2 E(): 0.0051
Smith-Waterman score: 207;  26.404% identity (52.247% similar) in 178 aa overlap (129-294:269-438)

      100       110       120       130       140       150        
KIAA11 KRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARA
                                     :::.. . .  :.   ..:    . .. : 
KIAA11 DQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQELSF--GVPYSHMMP--RRLSTQRY
      240       250       260       270         280         290    

      160            170       180        190       200       210  
KIAA11 RIQHR-----PPRQPTEYFDMGIFLAFFV-VVSLVCLILLVKIKLKQRRSQNSMNRLAVQ
       :.:.      ::  :  :.    :: .:. .. .    .   :.:    ..  :.    .
KIAA11 RLQQPLPPPPPPPPPPPYYPS--FLPYFLSMLPMSPTAMGPTISLDLDVDDVEMENY--E
          300       310         320       330       340         350

            220       230       240             250       260      
KIAA11 ALEKMETRKFNSKSKGRREGSCGALDTLS------SSSTSDCAICLEKYIDGEELRVIPC
       :: ..  :  ..: .:  ...   : .        .:  . :..:.  .   . :::.::
KIAA11 ALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPC
              360       370       380       390       400       410

        270       280       290       300       310       320      
KIAA11 THRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRGRQQRVTLPVHYPGR
       .:.:: :::: ::  ..::: :: .  :                                
KIAA11 NHEFHTKCVDKWLKANRTCPICRADASEVPREAE                          
              420       430       440                              




891 residues in 1 query   sequences
1986614 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:10:33 2008 done: Thu Dec 18 15:10:34 2008
 Total Scan time:  0.640 Total Display time:  0.020

Function used was FASTA [version 34.26.5 April 26, 2007]